Winter Newsletter 2012 - The Humane Research Trust
Transcription
Winter Newsletter 2012 - The Humane Research Trust
The Humane Research Trust Newsletter Winter 2012 Registered Charity No. 267779 GROUP NEWS This year has been a difficult one for fundraising, not only does the economic situation continue to be very challenging, but the extreme wet summer we experienced also put a lot of our fundraisers to the test. However, come rain or shine, our supporters manned stalls both inside and out, they continued to hold collections outside supermarkets and in the high street, and never failed to be anything but positive and cheerful – what a great team! BOURNEMOUTH GROUP Betty at Highcliffe Castle Christmas Fayre Our Bournemouth group were hit hard this summer after several events had to be cancelled due to inclement weather conditions. However, Pam and the team battled on and managed to organise two lovely Teddy Bear Tombolas, as well as holding stalls at both the Christmas Fayre at Highcliffe Castle and the Festive Gift Fair at the Bournemouth Pavilion. Thank you Pam and the rest of the Bournemouth group for fighting the elements and continuing to work hard to support The Trust. CHESHIRE GROUP Both Jacqui and Valerie have played an active part in our fundraising this year. Not only do they continue to volunteer at mail out times, giving up several of their days, 3 times a year, but they have also held stalls selling brick-a-brac at car boot and table top events. Thanks ladies, we really do appreciate everything you do to help The Trust. Janet and Hazel have joined other volunteers in giving up valuable spare time to help staff the Charity Christmas card shops held in several of our local libraries. Hazel has also managed to fundraise for us whilst attending the Northwest Working One of the Charity Christmas Dog Trials, selling some of our gifts and cards card shops held in a local library on a stall. The girls from the office also played their part by manning stalls at a local school fashion show, summer and Christmas fairs, as well as visiting a local nursing home to meet and chat with the residents whilst selling Christmas cards and gifts.They also attended both the Cheadle Hulme and Bramhall Methodist Church Christmas card sale and coffee mornings, which were extremely busy and sales of cards were the best ever! OBITUARY MR RICHARD GRENVILLE HAWKINS It is with deep sorrow that we have to report that Grenville Hawkins died peacefully in July 2012, aged 83. Grenvillle was a valued Trustee from 1976 to 1992 and kept in contact with The Trust after retiring. He always said he would be carried out in a cardboard box and his two nephews arranged a white cardboard coffin for him. He will be sadly missed by his nephews and many friends. COLCHESTER GROUP 2012 has been another extremely busy year for Elaine Watts, who heads up the Colchester Group. Not only does she hold a stall most Saturdays at the Mini Market, West Mersea, selling homemade cakes, vegetarian savouries and gifts, she also finds time to attend as many fetes, carnivals and table top sales as she can possibly fit in. She Mini market - West Mersea has attended The Aldham Old Time Rally, the Table Top Sale at the MICA Centre, the Wimpole Church Summer Fete, the East Mersea Summer Fete, the 80th Five Parishes Show, and the Mersea Island Summer Festival to name but a few. Thank you so much Elaine for all that you do for The Trust, and for giving up so much of your spare time to help raise funds! Brook House, 29 Bramhall Lane South, Bramhall, Cheshire SK7 2DN Telephone: 0161 439 8041 Fax: 0161 439 3713 E-mail: info@humaneresearch.org.uk Website: www.humaneresearch.org.uk MANAGEMENT CHANGES WITHIN THE TRUST Dear Supporter, I would inform you that Mr. Ken Cholerton retired as chairman of The Trust in May 2012. His term as chairman spanned 22 years and throughout that time his contribution to The Humane Research Trust has been one of commitment, leadership, dedication and promotion of our objectives, activities and strategic aims. During his chairmanship, the charity has become recognised and respected by university medical research institutions as well as by UK hospitals. Thankfully, Ken remains a Trustee and, therefore, his experience and wise counsel will still be available to us. ST ASAPH GROUP Pearl Davies, Group Secretary for the St Asaph group, has continued to work tirelessly for The Trust throughout the year, from organising coffee mornings, to attending fairs and carnivals such as the Gwrych Castle Fete, St Asaph Country Fair and the Abergele Carnival. One special evening event organised by Pearl involved a talk given by Dr’s Ian and Lynne Hampson, Abergele Carnival - August who work with The Trust. It was a great success and money was raised towards research into Ovarian Cancer. At the time of going to press, Pearl was in the throws of planning her next stall at the Christmas Party in the Street. Thank you Pearl for all you do and for helping to spread the word about the work we do. SUPPORTERS Thanks again to all of our head office volunteers (some of whom have already been mentioned above) for continuing to help us at mail out times. We couldn’t manage without them, plus it gives us the chance to chat and catch up with them all, which is always great fun! Jacqui Clarke, Sima Halimi, Hazel Holt, Eleanor Oatway,Valerie Woodward. Les Rhoades, Chairman of The Humane Research Trust I have a hard act to follow. I first became involved with the charity in 1995, having retired as a partner in a major accounting firm. As a volunteer, I became involved in the financial management of The Trust and I continued in this role becoming a Trustee in March 2012 and the chairman in the following May. I look forward to the challenges ahead and to continue the success that my predecessor has achieved over the years. Together with your support, which has been immense, I know that we can face the future with confidence. May I wish you a happy Christmas and fulfilling 2013 Best wishes Les Rhoades Chairman FUNDING LEADS TO LONG TERM DEVELOPMENT Professor Michael Coleman School of Life and Health Sciences, Aston University We would also like to thank Elaine Jacklin for arranging several collections outside Asda, Spondon, Tesco, Beeston and Long Easton and the Co-op, Stapleford. Thank you so much Elaine for all of your support and time throughout the year! STATISTICS OF SCIENTIFIC PROCEDURES ON LIVING ANIMALS GREAT BRITAIN 2011 CINDERELLA AND JASON FUND The following pets have been included with their personal message in our Book of Remembrance for pets here at Trust HQ. If you would like to include any animal please ask for our special Cinderella and Jason form. You will receive a comforting remembrance card confirming your personal message. Amber Briar LEGACIES FROM IN MEMORIAM Mrs Joyce Jellett – Chichester, West Sussex Miss Olive Campbell Mc Gregor – Maldon, Essex Mrs Jean Florence (Alex) Felgate – Lydney, Gloucestershire Mrs Esme Anne Maxfield Cotter – Kidlington, Oxfordshire Miss Ivy Jean Agnes Corney – Tywyn, Gwynedd Miss Robina (Rona)Stewart Hunter – Biggar, Larnarkshire Mrs Joan Lee – Compton, Surrey Miss Marion Beatrice Farley – Felixstow, Suffolk Miss Leanne Peace Mr Edgar Priestley Mrs Peggy Dorow Marjorie Crawley Mr John Skellet Mrs Frances Povey Mr William Arthur Bonner Norah Plant Holly Rowan Ellice Howard Mrs Grace Speight Mrs Ada Ions Mrs Anna Smith Mr Samuel Frank Jordan Mr Malcolm Wilcox Mrs Audrey Baldock Mr Victor Hale Marjorie Johnson important to note that the processes of developing ideas is costly in terms of time, so sustained support is essential to enable committed non-animal researchers to advance alternative methods to the point that they can appear to be viable to other scientists who currently work with animals.This sustained support from the Trust over the years has enabled us not only to design, test and develop experimental methods that are more relevant to man whilst eliminating animal suffering, but also we have been able to publish and provide human-based methods for other scientists to use. This will, in the intermediate and long term, benefit both man and animals. Tom Flowchart summary of Aston in vitro central nervous system (CNS) Research Support from The Trust was invaluable to the long-term development of our research group at Aston. The Trust’s funding allowed us to build a research ‘platform’ of important methods and published papers which enabled us to be successful in research council grant funding. Laboratory research requires personnel and material consumables and it is extremely labour intensive. No research development, no matter how vital or interesting, can be carried out without financial support. It is also Just over 3.79 million scientific procedures were started in Great Britain in 2011, an increase of 2 per cent. There were increases in the numbers of procedures for several species, for example, cats, pigs, birds and fish. There were falls in several species, for example, rats, guinea pigs, dogs and non-human primates. Breeding of genetically modified and harmful mutants - mainly mice remained stable, accounting for 1.62 million procedures. The number of non-toxicological procedures increased by 2 per cent to 3.39 million, reflecting the higher number of procedures carried out in universities (+7%). There were falls in the number of procedures used in ecology, anatomy, biochemistry, and cancer research, but increases in physiology, immunology and parasitology. London: The Stationery Office HC345 Crown Copyright 2012 MARGARET PRITCHARD MEMORIAL PRIZE October 2012 saw the second Margaret Pritchard Memorial Prize talks taking place at the University of Manchester. Like last year, PhD and MD candidates were invited to submit a short abstract describing the scientific and medical studies they were undertaking. We specifically asked that they be based around the topic of Cancer and that human models were used for all aspects of the study. year. The letter was submitted to, approved and supported by a wide selection of scientists, including Professor Michael Coleman and Dr Lindsay Marshall, School of Life and Health Sciences, Aston University who work with The Humane Research Trust. We welcome such informed and encouraging comment. Dr Ian Hampson, Dr Zhangjie Su, (second prize winner) and Mr Les Rhoades Dr Ian Hampson, Miss Manjula Doddananjaiah, (first prize winner) and Mr Les Rhoades Applicants were shortlisted and two were subsequently invited to come along and give a talk in the seminar room at St Mary’s Hospital.The successful students were Miss Manjula Doddananjaiah who described her work on the functions of a tumour suppressor protein known as p53 and Dr Zhangjie Su (recipient of last year’s award) who presented further data on his development of a new experimental approach for the imaging of brain tumours. There was a good audience for the talks and both speakers received many interesting questions regarding their projects. The hard and unenviable task of judging fell to Dr Ian Hampson (Viral Oncology Group Head), Mr Les Rhoades (Chairman of The Humane Research Trust) and Dr Anthony Oliver (The Humane Research Trust Monica Lumsden Research Fellow). With such a high standard of work it was an extremely close decision but this year the main prize went to Manjula and the runner up prize to Zhangiie. Both speakers were delighted with their awards, which were presented by Les and Ian. Everyone present thoroughly enjoyed the occasion and were unanimous in wishing Manjula and Zhangiie every success for the future. BRINGING COMMUNITIES TOGETHER: A CLEAR VIEW FOR ALL Dr Michael Wormstone – The University of East Anglia As group leader I believe it is important to present the findings of the laboratory. This not only promotes our work, but also engages different audiences, which can develop our research programme.Therefore, whenever an appropriate opportunity has come along I have attended meetings and presented our Immunofluorescence images latest findings. This has meant of human lens epithelial cells travelling as far as Hawaii to (200x magnification) speak at a meeting on cataract and the lens, which was established to engage scientists from the USA and Asia. In May, several members of the eye research group and I attended the ARVO meeting in Florida, which is the largest eye research conference in the world. More than 10,000 delegates attended this meeting. In July I attended the biannual ISER meeting in Berlin that had more than 1,000 participants from around the world. On this occasion, I organised a symposium on the major complication of cataract surgery known as Posterior Capsule Opacification.The majority of those attending these meetings were scientists, but I strongly believe that to make serious medical advances, clinicians need to be involved. Engagement of our laboratory with surgeons has been a key element in our general philosophy and I feel that much of our success has resulted from this approach. It is my feeling that scientists fundamentally perform the experiments, but through discussions with clinicians we determine the key questions that need to be answered. We can then in turn devise the best experimental methods to address these challenges. I therefore feel it is vitally important to attend clinical meetings to ensure that we do not lose touch with the LETTER PUBLISHED IN THE CHRIS PACKHAM TO HELP GUARDIAN JUDGE THE 2014 PET PHOTO The following letter was published in The Guardian earlier this CALENDAR COMPETITION medical problems we are trying to resolve. I was therefore thrilled when invited to speak at a one day symposium on ‘New Horizons in Cataract Surgery’, which was organised to celebrate the careers of two distinguished clinicians, Mr David Spalton and Mr Richard Packard who have recently retired.The speakers were a collection of world leaders in ophthalmology and it was an honour to be recognised in such company. The meeting was superb and I learnt a lot, but as a scientist the venue meant a great deal. The meeting was held in the main lecture theatre of the Royal Society, which is often regarded as the spiritual home of modern science. Isaac Newton, Michael Faraday and Charles Darwin have all graced the building and history is infused within its walls. To speak in such a place was a great honour and source of pride. Following the meeting, speakers and selected guests attended a celebratory meal at the Garrick Club, another grand setting. The walls were adorned with portraits by Millais and other great artists, but my lasting thought was a club rule. In the main dining room A suspended in vitro human there is a long table.Those wishing capsular bag to eat dinner there do not wander off and find their favourite table and limit themselves to a social group, but simply sit at the next available space and introduce themselves to the adjacent person. Thus the purpose of this rule is to engage with others that you otherwise may not. I believe interaction between scientists, clinicians, industry and the public are too disparate, with only a few attempting to bridge these gaps. I am proud that the laboratory reaches out to all these groups and hope that it is a model that others will follow in the future. Non-animal research needs more support This week the Home Office publishes its annual statistics for scientific procedures on animals. If recent trends are repeated, we are likely to see yet another increase in animal use. As scientists, we believe reducing and replacing animal use is not simply a legal or ethical imperative. Other compelling drivers include the urgent need for more human-relevant research results to improve disappointing clinical success rates for new medicines, innovation as an economic stimulus, and remaining competitive with global science leaders. A host of powerful human-biology-based cellular, genomic and computational tools are available that can often better predict people’s real-world reactions to drugs and chemicals than conventional animal tests. For many of us, replacing, reducing and refining animal experiments is driven by a desire to develop better approaches to researching human illness. Research innovation can bring huge societal benefits by improving the speed, reliability and human-relevance of the tools we use to answer biomedical questions. Britain has, in recent years, increased investment in non-animal research. But there is still much more we could do to lead the world. The EU’s Horizon 2020 framework programme for research and innovation funding provides an opportunity for Britain to demonstrate that leadership. We urge the UK government to support substantial, dedicated funding for emerging and future alternative technologies including such endeavours as mapping the “human toxome”. While there remains much vital debate within the scientific community about the efficacy of animal use, we scientists will undoubtedly be better equipped to tackle the major human health challenges of the 21st century if there is increased funding and support for sophisticated, human-relevant research. The Guardian, Monday 9 July 2012 Pet Photo Calendar The Competition held this year was a great success. Both the entry donations and large increase in sales of the calendar proved to be a great fundraiser, and ensured that The Humane Research Trust Pet Photo Calendar Competition is here to stay for years to come! The exciting news for our next competition is that one of our patrons, Chris Packham (English naturalist, nature photographer, television presenter and author), has very kindly agreed to help judge the competition and pick the final 12 winners and runners up. We are so grateful to Chris for agreeing to help as he is exceptionally busy with various television commitments, including the very popular Spring Watch. So in preparation for the competition, (full details to be announced in our Spring 2013 newsletter), please can you all look to take or find your favourite picture of your pet/pets that you think will best portray a month in the calendar i.e. for summer, a picture taken on a lovely sunny day, a leafy scene for autumn a wintery scene for our colder months and of course a nice festive scene for Christmas. Many thanks and let’s look forward to receiving lots of interest! CHRISTMAS CARD PHOTO COMPETITION As a result of the success of the Pet Photo Calendar Competition, we are also looking to run a Christmas Card Photo competition. The winner will see their photo as a Christmas card to be sold as part of our Christmas card range for 2013. Full details again will be printed in our Spring 2013 newsletter, but in the meantime, please can all those supporters looking to take part, start to think about what photo to enter. We will be looking for a photo that portrays the festive season at its best, i.e. a snowy scene, deer in the woods, festive pets or decoration etc etc. And who knows, Chris Packham may well help us to judge this too. PLEASE HELP - NEW GIFT AID RULES HM Revenue & Customs (HMRC) Charities have published new rules on Gift Aid declarations, without your help The Humane Research Trust could lose £1000’s each year. Please read the enclosed form carefully, and if we are able to claim Gift Aid on your donations, please complete it, and return to The Humane Research Trust as soon as possible. After 31 December 2012, The Humane REMEMBER to complete a new Gift Aid form if; Research Trust can only claim Gift Aid on GG You have a regular standing order You are planning to make one or more donations after the your donations if you have completed a new end of 2012 Gift Aid declaration form. If you are eligible G You add donations to your catalogue orders for Gift Aid and you are planning on making a donation to The Trust after this date you PREVIOUS GIFT AID FORMS WILL NOT BE VALID AFTER MUST complete the enclosed Gift Aid form. 31 DECEMBER 2012 PLEASE COMPLETE THE ENCLOSED NEW FORM MARGARET PRITCHARD MEMORIAL PRIZE October 2012 saw the second Margaret Pritchard Memorial Prize talks taking place at the University of Manchester. Like last year, PhD and MD candidates were invited to submit a short abstract describing the scientific and medical studies they were undertaking. We specifically asked that they be based around the topic of Cancer and that human models were used for all aspects of the study. year. The letter was submitted to, approved and supported by a wide selection of scientists, including Professor Michael Coleman and Dr Lindsay Marshall, School of Life and Health Sciences, Aston University who work with The Humane Research Trust. We welcome such informed and encouraging comment. Dr Ian Hampson, Dr Zhangjie Su, (second prize winner) and Mr Les Rhoades Dr Ian Hampson, Miss Manjula Doddananjaiah, (first prize winner) and Mr Les Rhoades Applicants were shortlisted and two were subsequently invited to come along and give a talk in the seminar room at St Mary’s Hospital.The successful students were Miss Manjula Doddananjaiah who described her work on the functions of a tumour suppressor protein known as p53 and Dr Zhangjie Su (recipient of last year’s award) who presented further data on his development of a new experimental approach for the imaging of brain tumours. There was a good audience for the talks and both speakers received many interesting questions regarding their projects. The hard and unenviable task of judging fell to Dr Ian Hampson (Viral Oncology Group Head), Mr Les Rhoades (Chairman of The Humane Research Trust) and Dr Anthony Oliver (The Humane Research Trust Monica Lumsden Research Fellow). With such a high standard of work it was an extremely close decision but this year the main prize went to Manjula and the runner up prize to Zhangiie. Both speakers were delighted with their awards, which were presented by Les and Ian. Everyone present thoroughly enjoyed the occasion and were unanimous in wishing Manjula and Zhangiie every success for the future. BRINGING COMMUNITIES TOGETHER: A CLEAR VIEW FOR ALL Dr Michael Wormstone – The University of East Anglia As group leader I believe it is important to present the findings of the laboratory. This not only promotes our work, but also engages different audiences, which can develop our research programme.Therefore, whenever an appropriate opportunity has come along I have attended meetings and presented our Immunofluorescence images latest findings. This has meant of human lens epithelial cells travelling as far as Hawaii to (200x magnification) speak at a meeting on cataract and the lens, which was established to engage scientists from the USA and Asia. In May, several members of the eye research group and I attended the ARVO meeting in Florida, which is the largest eye research conference in the world. More than 10,000 delegates attended this meeting. In July I attended the biannual ISER meeting in Berlin that had more than 1,000 participants from around the world. On this occasion, I organised a symposium on the major complication of cataract surgery known as Posterior Capsule Opacification.The majority of those attending these meetings were scientists, but I strongly believe that to make serious medical advances, clinicians need to be involved. Engagement of our laboratory with surgeons has been a key element in our general philosophy and I feel that much of our success has resulted from this approach. It is my feeling that scientists fundamentally perform the experiments, but through discussions with clinicians we determine the key questions that need to be answered. We can then in turn devise the best experimental methods to address these challenges. I therefore feel it is vitally important to attend clinical meetings to ensure that we do not lose touch with the LETTER PUBLISHED IN THE CHRIS PACKHAM TO HELP GUARDIAN JUDGE THE 2014 PET PHOTO The following letter was published in The Guardian earlier this CALENDAR COMPETITION medical problems we are trying to resolve. I was therefore thrilled when invited to speak at a one day symposium on ‘New Horizons in Cataract Surgery’, which was organised to celebrate the careers of two distinguished clinicians, Mr David Spalton and Mr Richard Packard who have recently retired.The speakers were a collection of world leaders in ophthalmology and it was an honour to be recognised in such company. The meeting was superb and I learnt a lot, but as a scientist the venue meant a great deal. The meeting was held in the main lecture theatre of the Royal Society, which is often regarded as the spiritual home of modern science. Isaac Newton, Michael Faraday and Charles Darwin have all graced the building and history is infused within its walls. To speak in such a place was a great honour and source of pride. Following the meeting, speakers and selected guests attended a celebratory meal at the Garrick Club, another grand setting. The walls were adorned with portraits by Millais and other great artists, but my lasting thought was a club rule. In the main dining room A suspended in vitro human there is a long table.Those wishing capsular bag to eat dinner there do not wander off and find their favourite table and limit themselves to a social group, but simply sit at the next available space and introduce themselves to the adjacent person. Thus the purpose of this rule is to engage with others that you otherwise may not. I believe interaction between scientists, clinicians, industry and the public are too disparate, with only a few attempting to bridge these gaps. I am proud that the laboratory reaches out to all these groups and hope that it is a model that others will follow in the future. Non-animal research needs more support This week the Home Office publishes its annual statistics for scientific procedures on animals. If recent trends are repeated, we are likely to see yet another increase in animal use. As scientists, we believe reducing and replacing animal use is not simply a legal or ethical imperative. Other compelling drivers include the urgent need for more human-relevant research results to improve disappointing clinical success rates for new medicines, innovation as an economic stimulus, and remaining competitive with global science leaders. A host of powerful human-biology-based cellular, genomic and computational tools are available that can often better predict people’s real-world reactions to drugs and chemicals than conventional animal tests. For many of us, replacing, reducing and refining animal experiments is driven by a desire to develop better approaches to researching human illness. Research innovation can bring huge societal benefits by improving the speed, reliability and human-relevance of the tools we use to answer biomedical questions. Britain has, in recent years, increased investment in non-animal research. But there is still much more we could do to lead the world. The EU’s Horizon 2020 framework programme for research and innovation funding provides an opportunity for Britain to demonstrate that leadership. We urge the UK government to support substantial, dedicated funding for emerging and future alternative technologies including such endeavours as mapping the “human toxome”. While there remains much vital debate within the scientific community about the efficacy of animal use, we scientists will undoubtedly be better equipped to tackle the major human health challenges of the 21st century if there is increased funding and support for sophisticated, human-relevant research. The Guardian, Monday 9 July 2012 Pet Photo Calendar The Competition held this year was a great success. Both the entry donations and large increase in sales of the calendar proved to be a great fundraiser, and ensured that The Humane Research Trust Pet Photo Calendar Competition is here to stay for years to come! The exciting news for our next competition is that one of our patrons, Chris Packham (English naturalist, nature photographer, television presenter and author), has very kindly agreed to help judge the competition and pick the final 12 winners and runners up. We are so grateful to Chris for agreeing to help as he is exceptionally busy with various television commitments, including the very popular Spring Watch. So in preparation for the competition, (full details to be announced in our Spring 2013 newsletter), please can you all look to take or find your favourite picture of your pet/pets that you think will best portray a month in the calendar i.e. for summer, a picture taken on a lovely sunny day, a leafy scene for autumn a wintery scene for our colder months and of course a nice festive scene for Christmas. Many thanks and let’s look forward to receiving lots of interest! CHRISTMAS CARD PHOTO COMPETITION As a result of the success of the Pet Photo Calendar Competition, we are also looking to run a Christmas Card Photo competition. The winner will see their photo as a Christmas card to be sold as part of our Christmas card range for 2013. Full details again will be printed in our Spring 2013 newsletter, but in the meantime, please can all those supporters looking to take part, start to think about what photo to enter. We will be looking for a photo that portrays the festive season at its best, i.e. a snowy scene, deer in the woods, festive pets or decoration etc etc. And who knows, Chris Packham may well help us to judge this too. PLEASE HELP - NEW GIFT AID RULES HM Revenue & Customs (HMRC) Charities have published new rules on Gift Aid declarations, without your help The Humane Research Trust could lose £1000’s each year. Please read the enclosed form carefully, and if we are able to claim Gift Aid on your donations, please complete it, and return to The Humane Research Trust as soon as possible. After 31 December 2012, The Humane REMEMBER to complete a new Gift Aid form if; Research Trust can only claim Gift Aid on GG You have a regular standing order You are planning to make one or more donations after the your donations if you have completed a new end of 2012 Gift Aid declaration form. If you are eligible G You add donations to your catalogue orders for Gift Aid and you are planning on making a donation to The Trust after this date you PREVIOUS GIFT AID FORMS WILL NOT BE VALID AFTER MUST complete the enclosed Gift Aid form. 31 DECEMBER 2012 PLEASE COMPLETE THE ENCLOSED NEW FORM The Humane Research Trust Newsletter Winter 2012 Registered Charity No. 267779 GROUP NEWS This year has been a difficult one for fundraising, not only does the economic situation continue to be very challenging, but the extreme wet summer we experienced also put a lot of our fundraisers to the test. However, come rain or shine, our supporters manned stalls both inside and out, they continued to hold collections outside supermarkets and in the high street, and never failed to be anything but positive and cheerful – what a great team! BOURNEMOUTH GROUP Betty at Highcliffe Castle Christmas Fayre Our Bournemouth group were hit hard this summer after several events had to be cancelled due to inclement weather conditions. However, Pam and the team battled on and managed to organise two lovely Teddy Bear Tombolas, as well as holding stalls at both the Christmas Fayre at Highcliffe Castle and the Festive Gift Fair at the Bournemouth Pavilion. Thank you Pam and the rest of the Bournemouth group for fighting the elements and continuing to work hard to support The Trust. CHESHIRE GROUP Both Jacqui and Valerie have played an active part in our fundraising this year. Not only do they continue to volunteer at mail out times, giving up several of their days, 3 times a year, but they have also held stalls selling brick-a-brac at car boot and table top events. Thanks ladies, we really do appreciate everything you do to help The Trust. Janet and Hazel have joined other volunteers in giving up valuable spare time to help staff the Charity Christmas card shops held in several of our local libraries. Hazel has also managed to fundraise for us whilst attending the Northwest Working One of the Charity Christmas Dog Trials, selling some of our gifts and cards card shops held in a local library on a stall. The girls from the office also played their part by manning stalls at a local school fashion show, summer and Christmas fairs, as well as visiting a local nursing home to meet and chat with the residents whilst selling Christmas cards and gifts.They also attended both the Cheadle Hulme and Bramhall Methodist Church Christmas card sale and coffee mornings, which were extremely busy and sales of cards were the best ever! OBITUARY MR RICHARD GRENVILLE HAWKINS It is with deep sorrow that we have to report that Grenville Hawkins died peacefully in July 2012, aged 83. Grenvillle was a valued Trustee from 1976 to 1992 and kept in contact with The Trust after retiring. He always said he would be carried out in a cardboard box and his two nephews arranged a white cardboard coffin for him. He will be sadly missed by his nephews and many friends. COLCHESTER GROUP 2012 has been another extremely busy year for Elaine Watts, who heads up the Colchester Group. Not only does she hold a stall most Saturdays at the Mini Market, West Mersea, selling homemade cakes, vegetarian savouries and gifts, she also finds time to attend as many fetes, carnivals and table top sales as she can possibly fit in. She Mini market - West Mersea has attended The Aldham Old Time Rally, the Table Top Sale at the MICA Centre, the Wimpole Church Summer Fete, the East Mersea Summer Fete, the 80th Five Parishes Show, and the Mersea Island Summer Festival to name but a few. Thank you so much Elaine for all that you do for The Trust, and for giving up so much of your spare time to help raise funds! Brook House, 29 Bramhall Lane South, Bramhall, Cheshire SK7 2DN Telephone: 0161 439 8041 Fax: 0161 439 3713 E-mail: info@humaneresearch.org.uk Website: www.humaneresearch.org.uk MANAGEMENT CHANGES WITHIN THE TRUST Dear Supporter, I would inform you that Mr. Ken Cholerton retired as chairman of The Trust in May 2012. His term as chairman spanned 22 years and throughout that time his contribution to The Humane Research Trust has been one of commitment, leadership, dedication and promotion of our objectives, activities and strategic aims. During his chairmanship, the charity has become recognised and respected by university medical research institutions as well as by UK hospitals. Thankfully, Ken remains a Trustee and, therefore, his experience and wise counsel will still be available to us. ST ASAPH GROUP Pearl Davies, Group Secretary for the St Asaph group, has continued to work tirelessly for The Trust throughout the year, from organising coffee mornings, to attending fairs and carnivals such as the Gwrych Castle Fete, St Asaph Country Fair and the Abergele Carnival. One special evening event organised by Pearl involved a talk given by Dr’s Ian and Lynne Hampson, Abergele Carnival - August who work with The Trust. It was a great success and money was raised towards research into Ovarian Cancer. At the time of going to press, Pearl was in the throws of planning her next stall at the Christmas Party in the Street. Thank you Pearl for all you do and for helping to spread the word about the work we do. SUPPORTERS Thanks again to all of our head office volunteers (some of whom have already been mentioned above) for continuing to help us at mail out times. We couldn’t manage without them, plus it gives us the chance to chat and catch up with them all, which is always great fun! Jacqui Clarke, Sima Halimi, Hazel Holt, Eleanor Oatway,Valerie Woodward. Les Rhoades, Chairman of The Humane Research Trust I have a hard act to follow. I first became involved with the charity in 1995, having retired as a partner in a major accounting firm. As a volunteer, I became involved in the financial management of The Trust and I continued in this role becoming a Trustee in March 2012 and the chairman in the following May. I look forward to the challenges ahead and to continue the success that my predecessor has achieved over the years. Together with your support, which has been immense, I know that we can face the future with confidence. May I wish you a happy Christmas and fulfilling 2013 Best wishes Les Rhoades Chairman FUNDING LEADS TO LONG TERM DEVELOPMENT Professor Michael Coleman School of Life and Health Sciences, Aston University We would also like to thank Elaine Jacklin for arranging several collections outside Asda, Spondon, Tesco, Beeston and Long Easton and the Co-op, Stapleford. Thank you so much Elaine for all of your support and time throughout the year! STATISTICS OF SCIENTIFIC PROCEDURES ON LIVING ANIMALS GREAT BRITAIN 2011 CINDERELLA AND JASON FUND The following pets have been included with their personal message in our Book of Remembrance for pets here at Trust HQ. If you would like to include any animal please ask for our special Cinderella and Jason form. You will receive a comforting remembrance card confirming your personal message. Amber Briar LEGACIES FROM IN MEMORIAM Mrs Joyce Jellett – Chichester, West Sussex Miss Olive Campbell Mc Gregor – Maldon, Essex Mrs Jean Florence (Alex) Felgate – Lydney, Gloucestershire Mrs Esme Anne Maxfield Cotter – Kidlington, Oxfordshire Miss Ivy Jean Agnes Corney – Tywyn, Gwynedd Miss Robina (Rona)Stewart Hunter – Biggar, Larnarkshire Mrs Joan Lee – Compton, Surrey Miss Marion Beatrice Farley – Felixstow, Suffolk Miss Leanne Peace Mr Edgar Priestley Mrs Peggy Dorow Marjorie Crawley Mr John Skellet Mrs Frances Povey Mr William Arthur Bonner Norah Plant Holly Rowan Ellice Howard Mrs Grace Speight Mrs Ada Ions Mrs Anna Smith Mr Samuel Frank Jordan Mr Malcolm Wilcox Mrs Audrey Baldock Mr Victor Hale Marjorie Johnson important to note that the processes of developing ideas is costly in terms of time, so sustained support is essential to enable committed non-animal researchers to advance alternative methods to the point that they can appear to be viable to other scientists who currently work with animals.This sustained support from the Trust over the years has enabled us not only to design, test and develop experimental methods that are more relevant to man whilst eliminating animal suffering, but also we have been able to publish and provide human-based methods for other scientists to use. This will, in the intermediate and long term, benefit both man and animals. Tom Flowchart summary of Aston in vitro central nervous system (CNS) Research Support from The Trust was invaluable to the long-term development of our research group at Aston. The Trust’s funding allowed us to build a research ‘platform’ of important methods and published papers which enabled us to be successful in research council grant funding. Laboratory research requires personnel and material consumables and it is extremely labour intensive. No research development, no matter how vital or interesting, can be carried out without financial support. It is also Just over 3.79 million scientific procedures were started in Great Britain in 2011, an increase of 2 per cent. There were increases in the numbers of procedures for several species, for example, cats, pigs, birds and fish. There were falls in several species, for example, rats, guinea pigs, dogs and non-human primates. Breeding of genetically modified and harmful mutants - mainly mice remained stable, accounting for 1.62 million procedures. The number of non-toxicological procedures increased by 2 per cent to 3.39 million, reflecting the higher number of procedures carried out in universities (+7%). There were falls in the number of procedures used in ecology, anatomy, biochemistry, and cancer research, but increases in physiology, immunology and parasitology. London: The Stationery Office HC345 Crown Copyright 2012