Program

53rd Symposium of
International
Society for
Clinical
Electrophysiology of
Vision
24–27 June 2015
Ljubljana, Slovenia
Programme and
Book of Abstracts
http://www.iscev2015.org/
Organised by:
International Society for Clinical Electrophysiology of Vision – ISCEV
Slovenian Society of Ophthalmology
Editors: Marko Hawlina, Jelka Brecelj (Chairs), Maja Šuštar, Martina Jarc Vidmar, Manca Tekavčič Pompe
Design: Brane Žalar
Published by: International Society for Clinical Electrophysiology of Vision - ISCEV
Slovenian Society of Ophthalmology
Printing:
CIP - Kataložni zapis o publikaciji
Narodna in univerzitetna knjižnica, Ljubljana
612.84.014.42(082)
617.7(082)
INTERNATIONAL Society for Clinical Electrophysiology of Vision. Symposium (53 ; 2015 ; Ljubljana)
Programme and book of abstracts / 53rd Symposium of International Society for Clinical Electrophysiology of
Vision, 24-27 June 2015, Ljubljana, Slovenia ; [organised by International Society for Clinical Electrophysiology of
Vision - ISCEV [and] Slovenian Society of Ophthalmology ; editors Marko Hawlina ... et al.]. - Europe : International
Society for Clinical Electrophysiology of Vision - ISCEV ; Ljubljana : Slovenian Society of Ophthalmology, 2015
ISBN 978-961-91886-4-4 (Slovenian Society of Ophthalmology)
1. Hawlina, Marko 2. Slovensko združenje oftalmologov
279868672
CONTENTS
Welcome Addresses .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. iii
Committees and Organisation.. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. iv
Programme at a Glance.. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. ..vi
Scientific Programme .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. vii
Information for Speakers and Poster Presenters.. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. xix
Registration and Fees .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. xix
Social Programme .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. ..xx
General Information .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. xxi
ISCEV Conference Abstracts .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. 1
Index of Authors .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. . 93
WELCOME ADDRESS
Dear members, friends, newcomers!
You are warmly invited to the 53rd ISCEV Symposium to be held in Ljubljana, the capital of Slovenia,
on 24–27 June 2015. We are very honoured to host the distinguished annual meeting of the Society for
Clinical Electrophysiology of Vision.
We have attended many ISCEV symposia, from our first – in Budapest in 1983 – to the most recent one, in
Boston last year, which gave us the opportunity to learn visual electrophysiology from the experts. This
experience enabled us to transfer the latest knowledge into our own routine work with the patients, as
well as encouraged our research endeavours. We sincerely hope that the mission of ISCEV 2015, which
is to present studies on ‘new findings in basic and clinical visual electrophysiology’, will attract many old
members and newcomers to share their experience and gain new knowledge. Throughout the years,
visual electrophysiology has become an important medical field, providing valuable diagnostic tools.
Nowadays, it is dealt with in ophthalmological textbooks and is relevant to many basic physiological,
pharmacological and veterinary aspects. Furthermore, electroretinography has been included in
neurological recommendations of the International Federation of Clinical Neurophysiology (IFCN). We
plan to devote one day of our Symposium, Wednesday, 24 June, to a joint meeting with the European
Neuroophthalmological Society (EUNOS) and thus create new opportunity for presentation of topics
that are relevant to both societies.
We shall do our best to assure the Ljubljana ISCEV Symposium provides you with new scientific and
practical knowledge, enrich you with a variety of new social contacts, and, as much as possible, also
with the beauties of Slovenian culture and country. We do hope you will leave Ljubljana with the same
good feelings and memories as we have cherished after attending the previous Symposia.
We look forward to welcoming you!
Marko Hawlina and Jelka Brecelj
iii
COMMITTEES AND ORGANISATION
Honorary Committee
Tine S Prevec
Martin Štrucl
Hisako Ikeda
Colin Barber
Günter Niemeyer
Eberhart Zrenner
Organising Committee
Marko Hawlina (Chair)
Jelka Brecelj (Chair)
Martina Jarc-Vidmar
Manca Tekavčič-Pompe
Maja Šuštar
Zoran Rodi
Scientific Committee:
Jelka Brecelj Scott Brodie
Marko Hawlina
Karen Holopigian
Zoran Rodi
Branka Stirn-Kranjc
Invited Speakers
Adachi Lecture: Richard Weleber, USA
Metabolic Disease with Choroidal Atrophy: Gyrate Atrophy and LCHADD
Dawson Lecture: Graham E. Holder, United Kingdom
The Role of Visual Electrophysiology in Neuro-ophthalmology.
Congress Secretariat
CANKARJEV DOM, Cultural and Congress Centre
Mrs. Alenka Kregar
Prešernova 10, SI-1000 Ljubljana, Slovenia
Phone: +386 1 24 17 133
Fax: +386 1 24 17 296
E-mail: alenka.kregar@cd-cc.si
Venue
Cankarjev dom, Cultural and Congress Centre
Prešernova 10, SI-1000 Ljubljana, Slovenia
Phone: +386 1 241 7100
Fax: +386 1 241 7296
iv
ACKNOWLEDGEMENTS
The Organising Committee is deeply appreciative of the sponsorship generously provided by the following
companies:
General Sponsor
Golden Sponsor
Silver Sponsors
Bronze Sponsor
Exhibitor
v
PROGRAMME AT A GLANCE
Time
7:30
9:00
9:30
10:00
10:30
11:00
11:30
12:00
12:30
13:00
13:30
14:00
14:30
15:00
15:30
16:00
16:30
17:00
17:30
Sunday, June 21
EUNOS
Monday, June 22
EUNOS
Headache and
intracranial
hypertension
Jay
Kesler
Digre
Tuesday, June 23
EUNOS
Research Ctee
Symposium
Trauzettel
Klosinski
Wednesday, June 24
EUNOS/ISCEV
ISCEV
Case
Reports
Session
Coffee break
Coffee break
Coffee break
Registration
Eye movements
and Pupil
Kennard
Antoniades
Zrenner
Bremner
Mitochondrial
diseases
Symposium
Yu Wai Man
Buffet Lunch
with Posters
1
Buffet Lunch
with Posters
2
Pediatric NeuroOphthalmological
Symposium
Landau,
Brodsky, Gottlob, Leiba,
Gerth Kahlert
Illusisons,
Hallucinations,
Neglect and
Rehabilitation
Plant, Malhotra,
Trauzettel Klosinski,
Rowe
Coffee break
Coffee break
Optic Neuropathies I
Arnold: NAION
Arndt: TC in NAION
Frederiksen: ON
Hickman: Phenytoin
Optic Neuropathies II
Hedges: GCC
Dotan: Toxic
Akdal: Behcet
De Keizer: Orbit
Course 1
Eye Movements
Kennard
Antoniades
Ji-Soo Kim
Coffee break
Course 2
Electrophysiology
Holder, Hawlina,
Brecelj
Break
Course 3
18:00
Nystagmus
Gottlob,
18:30 Proudlock, Pilat, McLean
19:00
19:30
20:00
20:30
21:00
21:30
22:00
Controversy debate
US or biopsy in GCA
Landau vs. Jay
Group photo
Opening and
Welcome Party
Club CD
Membership
Meeting
Friday, June 26
ISCEV
Paper
Session
5
Toxicology &
Treatment
Saturday, June 27
ISCEV
Paper
Session
8
Retinal
Function &
Structure
Coffee break
Coffee break
Paper
Session
6
Retinal
Diseases
Coffee break
Dodt &
Marmor
Award
Introductory Lecture
D. McCulloch
Paper
Session
EUNOS
Electrophysiology
Paper
Session
3
Pediatric
Electrophysiology
Lunch
Symposium
with Sponsors
Lunch
Lunch
Joint Poster
Session 1
EUNOS/ISCEV
Poster
Session 2
Introductory L.
P. Lachapelle
Coffee break
Coffee break
Introductory Lecture
R. Weleber
Paper
Session
4
Methodological
aspects of
Electrophysiology
ISCEV Paper
Session
1
NeuroOphthalmology
Paper
Session
7
Animal Electrophy.
Coffee break
Membership
Meeting
Congress Closing
Lunch
ISCEV
Olympics
& Picnic
Lake Bled
Group photo
Adachi
Award
Lecture
R. Weleber
Free
evening
Free
evening
ISCEV COURSES
Monday, June 22, 2015
8:30 – 17:30
Tuesday, June 23, 2015
8:30 – 16:00
vi
Congress Opening
W. Dawson
Memorial
Lecture
G.E. Holder
Thursday, June 25
ISCEV
Paper
Session
2
Retinal &
Optic Nerve
Function &
Treatment
ISCEV
Welcome
Reception
Ljubljana
Castle
EUNOS
Conference Dinner
Free
evening
ISCEV
Conference
Dinner
Club CD
ISCEV COURSES TIMETABLE
Monday, June 22, 2015
Human Course – Hall M3,4
08:30 – 08:45
Animal Course – Hall M3,4
Introduction to the course, faculty, expectations and structure
Dorothy Thompson
08:45 – 09:30
Introduction to full field ERGs
Suresh Viswanathan
Physiology of ERGs ( Basic components, Cellular sources, Functional relationships (Naka-Rushton))
ISCEV Full field ERG Standard (Recording protocols and their physiological basis)
Additional diagnostic resources (a-wave modelling, PhNR, On-Off-, chromatic and S-cone stimulation)
09:30 – 10:15
Clinical application of full field ERG
Tony Robson
Interpreting ISCEV Full field standard ERGs (Patterns of change to track down the underlying pathophysiology)
Diagnostic challenges in health and disease (Distinguishing rod and cone photoreceptor contributions, limited vs.
generalised disease, negative ERGs)
Human Course – Hall M3,4
Animal Course – Hall M2
10:15 – 10:45
Coffee break
10:45 – 11:30
Techniques to localise retinal stimulation PERG & mfERG Imaging (practical demonstration)
Michael Bach
Travel to demonstration site – Medical Faculty
11:30 – 12:15
Clinical application of mfERG and PERG
Imaging (practical demonstration)
Tony Robson
Mathias Seeliger + faculty
Demonstrations of SLO/OCT experimental in vivo
imaging
12:15 – 13:00
Sandwich lunch
13:00 – 13:30
Techniques of VEP recording
Imaging (practical demonstration)
Michael Bach
Travel from demonstration site (extd. lunch) – Medical
Faculty
Clinical applications of the VEP
Preclinical imaging (OCT, SLO)
Jelka Brecelj
Mathias Seeliger
13:30– 14:10
OCT, SLO & angiography as structural biomarkers,
preclinical models & therapeutic interventions
14:10 – 14:35
14:35 – 15:00
EOG recording and its clinical applications
ERG in retinal research 1 (inner retina)
Dorothy Thompson
Suresh Viswanathan
Non-standard ERGs (red flash & S-cone)
Experimental use of ERG, PHNR& PERG with focus on
Glaucoma & ON disease in rats & large animals
Chris Hogg
15:00 – 15:30
Coffee break
15:30 – 16:15
Recognising everyday common artefacts
ERG in retinal research 2 (outer retina)
Ruth Hamilton
Mathias Seeliger
Experimental use of ERG in inherited diseases affecting
RPE, photoreceptors and bipolar cellst
16:15 – 17:30
19:00
Clinical practical demonstrations – Second Foyer
Extraction of specific ERG components
Dorothy Thompson, Tony Robson, Chris Hogg, Manca
Tekavcic Pompe, Ruth Hamilton, Maja Šuštar
Christoph Friedburg
6 equipment stations demonstrating
1) Full field ERG
2) MfERG/PERG
3) PERG/PVEP
& range of electrodes: DTL, GF, HK loop, skin
Approaches to unravel rod and cone contributions to the
ERG via methods, like a-wave analysis and paired flash
paradigms
Course dinner with faculty
vii
Tuesday, June 23, 2015
Human Course – Hall M3,4
08:30 – 09:00
Animal Course – Hall M3,4
A diagnostic approach to retinal disorders
Tony Robson
09:00 – 09:40
Part 1: Experimental ERG in the discovery of novel aspects of retinal function & pathophysiology
Mineo Kondo
Experimental ERG in the discovery of novel aspects of retinal function
Diagnostic insights to better understand the underlying pathophysiology
09:45 – 10:15
Part 2: ERG in Preclinical Therapy Assessment
Mathias Seeliger
ERG recordings as functional biomarker
Follow up of therapeutic interventions in pre-clinical models of rod (RP) and cone (ACHM2) disease
Human Course – Hall M3,4
Animal Course – Hall M2
10:15 – 10:45
Coffee break
10:45 – 11:05
Maturation of visual electrophysiological measures
Fundamentals of ERG in animal models
Ruth Hamilton
Bo Lei
Recording in animals (equipment and materials)
‘ISCEV’ standard (basic and extended tests)
11:05 – 11:25
11:30 – 12:15
The chiasm and the VEP
ERG (practical demonstrations)
albinism /achiasmia
Mathias Seeliger & faculty
Jelka Brecelj
ERG demonstrations with a rodent phantom
(light-sensitive, “artificial” mouse/ra)
Paediatric techniques in an outpatient setting
Dorothy Thompson
12:15 – 13:00
Sandwich lunch
Hall M3,4
13:00 – 14:00
System overview and calibration
Chris Hogg
What do I need to do to set up a lab
General considerations (shielded room, isolation, power cables, accessibility)
Scope of diagnostics (which test equipment, which age group)
Equipment comparison
What do I need to know before I buy?
Technical considerations (amplifiers, filters, flexibility of programming, stimulators, external triggers)
How to make a dummy patient photocell
Equipment questionnaire
14:00 – 15:00
Human Course – Hall M3,4
Animal Course – Hall M2
Comprehensive clinical visual electrodiagnostics
Comprehensive animal diagnostics
Graham Holder
Mathias Seeliger, Bo Lei, Suresh Viswanathan
An overview and integration of the clinical test findings
Complementary phenotyping of animal models based
on ERG and imaging techniques
15:00 – 15:30
Coffee break
15:30 – 16:00
Time with manufacturers
Time with imaging manufacturers
Comparison of specifications & practise
Comparison of specifications & practise
16:00
viii
Course finish and feedback
ISCEV CONFERENCE TIMETABLE
53rd ISCEV Symposium and 12th EUNOS Congress joint day
Wednesday, June 24, 2015
Linhart hall
09:00 – 10:15
Case reports session
Moderators: Michael Marmor, Richard Smith
10:15 – 10:45
Coffee break
10:45 – 11:00
Opening ceremony of the congress
11:00 – 11:50
William Dawson memorial lecture
Electrophysiology in neuro-ophthalmology
Graham E. Holder (UNITED KINGDOM)
Introduction: Marko Hawlina (SLOVENIA)
11:50 – 13:00
Electrophysiology - EUNOS
Moderators: Shuichi Yamamoto, Eberhart Zrenner
11:50
Introductory lecture: Current status of microelectronic aids in fighting blindness
Eberhart Zrenner (GERMANY)
12:20
Follow-up of a new automated perimetry protocol based on the multifocal ERG compared to the G2 perimetry
Livia Brandao, Matthias Monhart, Andreas Schötzau, Anna Ledolter, Anja Palmowski-Wolfe (SWITZERLAND)
12:30
Multifocal visual evoked potentials in patients with optic disc drusen
Lasse Malmqvist, Clare Fraser, Luis De Santiago, Alexander Klistorner, Steffen Hamann (DENMARK)
12:40
Presumable persistent placoid maculopathy: A case report after 1-year follow-up with
multimodal imaging and electroretinography
Andre Messias, Katharina Messias, Fernanda Crotti, Rogério Costa (BRAZIL)
12:50
Retrograde maculopathy
Mathias Abegg (SWITZERLAND)
13:00 – 13:10
Break
13:10 – 14:30
Lunch symposium with sponsors
Moderators: Jorge Arruga Ginebreda (SPAIN), Mathias Seeliger (GERMANY)
13:10
Clinical experience with Idebenone (Raxone®) in the treatment of patients with Leber’s hereditary optic
neuropathy (LHON)
Günther Metz, Santhera (SWITZERLAND)
13:20
Identification of aqueous and lipid deficient dry eye - Optive Family of Allergan
Špela Štunf, Eye Hospital, University Medical Centre Ljubljana (SLOVENIA)
13:30
Innovations in the Roland Product line
Joachim Finger, Roland Consult (GERMANY)
13:40
About animal research with RETImap ERG, mf ERG OCT, AF results and technique
M. M. Mai, Roland Consult (GERMANY)
13:50
New developments in animal testing
Diagnosys Ltd. (UNITED KINGDOM)
14:00
LKC RETeval and it's use around the world
James J. Datovech, LKC Technologies Inc. (UNITED STATES)
14:10
CSO-Advanced diagnostic systems in ophthalmology
Claudio Baglini, CSO, Florence (ITALY)
14:20
Discussion
ix
14:30 – 15:30
Poster session 1 - Neuro-ophthalmology - Poster/Second foyer
Moderators: Martina Jarc-Vidmar, Manca Tekavcic-Pompe, Anthony G. Robson
P01
Longitudinal study of retinal and optic nerve function in patients with multiple sclerosis – a baseline report
Christina Gerth-Kahlert, Klara Landau, James V.M. Hanson (SWITZERLAND)
P02
Visual evoked potentials in ON-pathway disorders
Dennis Fritsch, Valeria Ricotti, Francesco Muntoni, Stephanie Grunewald, Jane Sowden, Dorothy Thompson (UNITED KINGDOM)
P03
A BOLD venture: comparison of VEP with functional near-infrared spectroscopy and functional magnetic
resonance imaging for assessment of visual acuity
Torsten Straßer, Dominic Hillerkuss, Lukasz Lisowski, Sabrina Schneider, Florian Häußinger, Michael Erb, Andreas J.
Fallgatter, Klaus Scheffler, Eberhart Zrenner, Ditta Zobor (GERMANY)
P04
A case of optic atrophy and retinal degeneration with low mitochondrial respiratory enzyme V activity
Hiroko Yamazaki, Yuzhu Chai, Yasushi Ooya (JAPAN)
P05
Electrophysiologic analysis of visual complications, specifically optic atrophy, from graft vs host disease
Stephanie Lao, Margaret C. Hubbell, Amanda Selchau, Terry Wood (UNITED STATES)
P06
Comparison of electroretinographical responses in albinism, idiopathic infantile nystagmus and healthy controls
Zhanhan Tu, Christopher Degg, Viral Sheth, Irene Gottlob, Frank Proudlock (UNITED KINGDOM)
P07
Vitamin A deficiency retinopathy: one year follow up
Evelyn Longhin, Elisabetta Pilotto, Enrica Convento, Alma Patrizia Tormene, Edoardo Midena (ITALY)
P08
Clinical case: multifocal ERG demonstrates residual abnormality years after traumatic macular injury in an eye
with 20/20 vision
Linden Doss, Terry Wood (UNITED STATES)
P09
High-resolution imaging of patients with Bietti crystalline dystrophy with CYP4V2 mutation
Kiyoko Gocho, Shuhei Kameya, Keiichiro Akeo, Sachiko Kikuchi, Ayumi Usui, Kunihiko Yamaki, Takaaki Hayashi, Hiroshi
Tsuneoka, Atsushi Mizota, Hiroshi Takahashi (JAPAN)
14:30 – 15:30
Poster session 1 - Inner retinal function and the optic nerve – Poster/Second foyer
Moderators: Martina Jarc-Vidmar, Manca Tekavcic-Pompe, Anthony G. Robson
P10
Functional and structural characteristics of early glaucoma
Maja Šuštar, Darko Perovšek, Barbara Cvenkel (SLOVENIA)
P11
Can variability of pattern ERG signal help to detect retinal ganglion cells dysfunction in glaucomatous eyes?
Alberto Mavilio, Francesca Scrimieri, Donato Errico (ITALY)
P12
Comparison of pattern ERG and focal macular PhNR to evaluate the ganglion cell function
Souichi Matsumoto, Kazuma Yagura, Kei Shinoda, Harue Matsumoto, Atsushi Mizota (JAPAN)
P13
Functional assessment of pre-ganglion and ganglion cell level in autosomal dominant optic atrophy by PERGLA,
PERG and MULTIFOCAL ERG
Gabriella Cammarata, Gemma Tremolada, Paola Ciasca, Chiara Manclossi, Costanza Lamperti, Eleonora Lamantea,
Stefania Bianchi Marzoli (ITALY)
P14
Red-blue pupil reaction and the melanotic ganglion cell response
Audrey Chia, Daniel Kai Peng Chua, Li Yu Chen, Rena Png (SINGAPORE)
14:30 – 15:30
Poster session 1 – Pediatric electrophysiology – Poster/Second foyer
Moderators: Martina Jarc-Vidmar, Manca Tekavcic-Pompe, Anthony G. Robson
P15
Paediatric electrodiagnosis in Hong Kong
Carol Po-Sang Lam, Winnie Wai Ying Lau, Carmen Kar Mun Chan, Andrew Chung Tin Fok (HONG KONG)
P16
Electroretinogram changes in retinopathy of prematurity after photocoagulation
Hongbo Cheng, Guoming Zhang, Feng Wen, Shizhou Huang, Dezheng Wu (CHINA)
P17
Evaluation of visual function by visual evoked potentials prior to surgery for congenital cataract
Hande Taylan Sekeroglu, Kadriye Erkan Turan, Ali Sefik Sanac (TURKEY)
P18
Comparison between ERG after photocoagulation and ERG after intravitreal injection of ranibizumab for treating
retinopathy of prematurity
Guoming Zhang, Hongbo Cheng, Jun Mei, Linli Wang, Honghui He (CHINA)
x
P19
Electroretinograms in idiopathic infantile nystagmus, optic nerve hypoplasia, and albinism, in comparison to
healthy controls and early-onset retinal dystrophies
Alma Kurent, Branka Stirn-Kranjc, Jelka Brecelj (SLOVENIA)
14:30 – 15:30
Poster session 1 – Toxicology and treatment - Poster/Second foyer
Moderators: Martina Jarc-Vidmar, Manca Tekavcic-Pompe, Anthony G. Robson
P20
Aripiprazole induced chorioretinopathy
Matthieu Robert, Isabelle Audo, Christina Zeitz, Jean-Bernard Letessier, Celine Faure (FRANCE)
P21
Photopic response before and after vitreous removal during vitreous surgery
Kei Shinoda, Soiti Matsumoto, Gaku Terauchi, Goichi Akiyama, Harue Matsumoto, Atsushi Mizota, Yozo Miyake (JAPAN)
P22
MfERG assessment of hydroxychloroquine toxicity
Enid Chelva, Monika Dolliver, Sarina Laurin, Terri Mclaren, John De Roach (AUSTRALIA)
P23
Multifocal ERG analysis of primary CNS lymphoma with ocular manifestations
Margaret Hubbell, Amanda Selchau, Stephanie Lao, John Hamilton, Mark Pennesi, Terry Wood (UNITED STATES)
P24
Retinal functional changes associated with anti- VEGF treatment in subjects with wet ARMD
Güliz Fatma Yavas, Tuncay Kusbeci, Umit Ubeyt Inan (TURKEY)
P25
Insidious hydroxychloroquine macular toxicity: a case report
Livia Brandao, Anja Palmowski-Wolfe (SWITZERLAND)
15:30 – 16:00
Coffee break
16:00 – 18:00
Paper session 1 – Neuro-ophthalmology – Oral/Linhart hall
Moderators: Graham E. Holder, Marko Hawlina
16:00
Introductory lecture: Paraneoplastic and autoimmune retinopathy
Richard Weleber (UNITED STATES)
16:30
Retrospective analysis of the progression of electrophysiological changes after the first visual symptoms in
juvenile onset optic neuritis
Márta Janáky, Imre Fejes, Rita Alács, György Benedek, Gábor Braunitzer (HUNGARY)
16:45
Visual pathways in humans with ephrin-B1 deficiency
Michael Hoffmann, Hagen Thieme, Karin Liedecke, Synke Meltendorf, Juliane Reupsch, Martin Zenker, Ilse Wieland (GERMANY)
17:00
Genetic associations to the ERG in autism spectrum disorder
Paul Constable, Sebastian Gaigg, Dermot Bowler, Dorothy Thompson (UNITED KINGDOM)
17:15
Structural and functional effects of dysmyelination in a large animal model
James Verhoeve, Michael Nork, Leandro Teixeira, Richard Dubielzig, Abigail Radcliff, Ian Duncan (UNITED STATES)
17:30
Naso-temporal thickness of the retinal ganglion cell layer by OCT-segmentation in lesions of the visual pathway
Hannes G. H. Wildberger, Werner Wichmann, Klara Landau, Luca Regli, Christina Gerth-Kahlert (SWITZERLAND)
17:45
Evidence for compartment syndrome damage in a primate model of non-arteritic anterior ischemic optic
neuropathy (pNAION)
20:00 – 23:00
Welcome reception/Ljubljana castle (together with EUNOS)
Mary Johnson, Neil Miller, Steven Bernstein (UNITED STATES)
xi
EUNOS Poster session 3
Electrophysiology, toxic states, methods (Second foyer)
Moderators: Gabriella Szatmary (UNITED STATES), Jan Willem Pott (NETHERLANDS), Anja Palmowski-Wolfe
(SWITZERLAND)
PE094
Comparison of electroretinographical responses in albinism, idiopathic infantile nystagmus and healthy controls
Zhanhan Tu, Christopher Degg, Viral Sheth, Irene Gottlob, Frank Proudlock (UNITED KINGDOM)
PE095
Retinal ganglion cell volume correlates with pattern electroretinogram in acute optic neuritis
Justin Mckee, Charles Cottriall, John Elston, Lars Fugger, Chris Kennard, Nikos Evangelou, Jacqueline Palace, Matthew
Craner (UNITED KINGDOM)
PE96
Methanol toxicity: Bangladesh perspective
Sarwat Rahman (BANGLADESH)
PE97
Ketamine affects single vesicle exocytosis in cultured rat astrocytes
Eva Lasič, Matjaž Stenovec, Mićo Božić, Saša Trkov, Marko Kreft, Vladimir Grubišić, Vladimir Parpura, Robert Zorec
(SLOVENIA)
PE98
Tamoxifen-induced optic neuropathy or NAION?
Idit Maharshak (ISRAEL)
PE99
Intracellular cAMP and Ca2+ signalling in cultured rat astrocytes
Anemari Horvat, Nina Vardjan, Robert Zorec (SLOVENIA)
PE100
Low vision in multiple sclerosis
Andreia Soares, João Cerqueira, Cristina Almeida, Fernando Vaz (PORTUGAL)
PE101
Novel update 2015: It is more than a library
Kathleen Digre, Nancy Lombardo, Chrisy Jarvis, Valerie Biousse, Aki Kawasaki (UNITED STATES)
PE102
Use of non-mydriatic wide-field retinography for periphlebitis detection in patients with multiple sclerosis
Ruben Torres-Torres, Elena Fraga-Pumar, Elena H. Martínez-Lapiscina, Pablo Villoslada, Bernardo F. Sanchez-Dalmau
(SPAIN)
PE103
Visual dysfunction induced by cobalt toxicity
Bernardo Sanchez Dalmau, Amélia Maria De Carvalho, Cristina Nieto, Christian Fontecilla, Ruben Torres Torres,
Santiago Nogués, Jenaro Angel Fernández-Valencia (SPAIN)
PE104
Quantification of retinal ganglion cell loss detected by spectral domain optical coherence tomography in
patients with stroke
Stefania Bianchi Marzoli, Lisa Melzi, Ciasca Paola, Gabriella Cammarata, Carlotta Casati, Giuseppe Vallar, Nadia
Bolognini (ITALY)
PE105
Abnormal optic nerve head morphology in albinism imaged using high resolution spectral domain optical
coherence tomography
Frank Proudlock, Sarim Mohammad, Viral Sheth, Anastasia Pilat, Helena Lee, Ellen Pollheimer, Irene Gottlob (UNITED
KINGDOM)
PE106
High resolution imaging of the optic nerve and retina in optic nerve hypoplasia
Anastasia Pilat, Daniel Sibley, Rebecca McLean, Frank Proudlock, Irene Gottlob (UNITED KINGDOM)
PE107
A prospective study on the prevalence of microcystic macular changes on optical coherence tomography of the
macular region in optic nerve atrophy of non-neuritis origin
Jan Willem Pott, Willemien De Vries, Axel Petzold (NETHERLANDS)
PE108
Analysis of the macular ganglion cell layer of patients with vascular lesions of the posterior pathway
Rita Anjos, André Vicente, Livio Costa, Arnaldo Santos, Duarte Amado, Joana Ferreira, João Paulo Cunha (PORTUGAL)
PE109
Unusual acquired temporal sectoral scotomas
M.J. Gilhooley, Clare Fraser, Gordon T. Plant (UNITED KINGDOM)
PE110
The role of B-cells in early onset acute optic neuritis
Ruth Huna-Baron, Anna Feldman, Michael Gurevich, Anat Achiron (ISRAEL)
PE111
Unilateral optic neuritis and venous sinus thrombosis related to myelin-oligodendrocyte glycoprotein
antibodies: A case report
Maribel Acuna Salles, Pedro Pascual Ruiz, Laura Cabrejas Martínez, Miguel Ángel Alonso Peralta, Viviana Lezcano
Carduz, Cristina Molero Langa (SPAIN)
xii
PE112
Adult malignant optic pathway glioma mimics a bilateral sequential anterior ischaemic optic neuropathy
Viviana Lezcano Carduz, Miguel Ángel Alonso Peralta, Cristina Molero Langa, Maribel Acuña Salles, Laura Cabrejas
Martinez (SPAIN)
PE113
Changes in macular layers in the early course of non-arteritic ischaemic optic neuropathy
Bernardo Sanchez Dalmau, Johannes Keller, Pablo Villoslada (SPAIN)
PE114
Steroid-dependent autoimmune optic neuropathy: Case series
Ainat Klein, Anat Kesler (ISRAEL)
PE115
Association of 25-hydroxyvitamin D levels with RNFL and GCL thickness and clinical tests of visual function in
acute optic neuritis
Gorm Pihl-Jensen, Kiren Farooq, Jette Frederiksen (DENMARK)
PE116
The time course of retinal ganglion cell layer loss after non-arteritic anterior ischaemic optic neuropathy
Bao-Khanh Tran, François-Xavier Borruat (SWITZERLAND)
PE117
My wife says I can´t drive …
Mónica Loureiro, Lígia Ribeiro, David Tente, António Figueiredo Lopes, Óscar Alves, Dália Meira (PORTUGAL)
PE118
Retrobulbar optic neuritis in neuroborreliosis: A case report
Monika Sarnat-Kucharczyk, Dorota Pojda-Wilczek, Ewa Mrukwa-Kominek (POLAND)
Thursday, June 25, 2015
Linhart hall
09:00 – 10:45
Paper session 2 – Retinal and optic nerve function and treatment – Oral
Moderators: Márta Janáky, Enid Chelva
09:00
Detecting glaucoma with photopic negative response
Marta Kiszkielis, Wojciech Lubiński, Krzysztof Penkala (POLAND)
09:15
Exploring the methods of data analysis in multi focal visual evoked potentials (mfVEP)
Lasse Malmqvist, Clare Fraser, Luis De Santiago, Alexander Klistorner, Steffen Hamann (DENMARK)
09:30
Interocular difference of retinal ganglion cell function measured by objective and subjective methods
Imre Fejes, Péter Balázs Kocsis, Márta Janáky (HUNGARY)
09:45
Electrophysiology and colour: a comparison of methods to evaluate inner retinal function
Anne Kurtenbach, Christoph Kernstock, Eberhart Zrenner, Hana Langrová (GERMANY)
10:00
Electroretinographic evidence supportive of an organic cause in some forms of functional amblyopia
Raquel Beneish, Allison Dorfman, Ayesha Khan, Robert Polomeno, Robert Koenekoop, Pierre Lachapelle (CANADA)
10:15
Quality and quantity of rescue in retinal gene therapy: implications for vision
Mathias Seeliger, Vithiyanjali Sothilingam, Naoyuki Tanimoto, Marina Garcia Garrido, Susanne C Beck, Christian Schoen,
Martin Biel, Stylianos Michalakis, Regine Mühlfriedel (GERMANY)
10:30
Treatment with transcorneal electric stimulation (TES) in hereditary retinal degeneration
Eberhart Zrenner, Florian Gekeler, Mariya Gosheva, Andreas Schatz (GERMANY)
10:45 – 11:15
Coffee break
11:15 – 13:00
Paper session 3 – Pediatric electrophysiology – Oral
Moderators: Dorothy Thompson, Jelka Brecelj
11:15
Introductory lecture: Electrophysiologic exploration of early visual development in human infants
Daphne L. McCulloch (CANADA)
11:45
Retinal dystrophy in young patients presenting as refractory intermediate uveitis
Ymkje Marije Hettinga, Maria van Genderen, Wietse Wieringa, Annette Ossewaarde, Joke De Boer (NETHERLANDS)
xiii
12:00
Decreased foveal function causing faster myopic progression in children
Serena Zhe Chuang Li, Allen Ming Yan Cheong, Chea Su Kee, Henry Ho Lung Chan (CHINA)
12:15
Electrophysiological evaluation of superior and inferior visual fields in healthy schoolchildren
Manca Tekavcic Pompe, Maja Šuštar, Branka Stirn Kranjc, Jelka Brecelj, Katja Groleger Sršen (SLOVENIA)
12:30
Flash VEP in children with meningitis
Raman Prasad Sah, Jyoti Baba Shrestha (NEPAL)
12:45
Follow-up of electroretinogram and visual evoked potentials as markers of retinal dystrophy and phenotypegenotype relationship in a large sample of children affected by Joubert syndrome
Alice Tarantola, Giulio Ruberto, Enza Maria Valente, Chiara Bertone, Mauro Antonini, Sabrina Signorini, Carmine Tinelli,
Umberto Balottin, Paolo Emilio Bianchi (ITALY)
13:00 – 14:30
Lunch
14:30 – 15:30
Poster session 2 – Methodological aspects of electrophysiology – Poster/Second foyer
Moderators: Ruth Hamilton, Mineo Kondo, Serge G. Rosolen
P26
Four decades of visual electrophysiology in Slovenia
Jelka Brecelj (SLOVENIA)
P27
LED-based tunable light source for visual electrophysiology
Gregor Belušič, Marko Ilić, Katja Horvat, Primož Pirih (SLOVENIA)
P28
Scotopic red ERG findings
Li Yu Chen, Rena Png, Ranjana Mathur, Audrey Chia (SINGAPORE)
P29
Multi-stage ANC filter applied to mfVEP recordings
Miguel Ortiz, Luis De Santiago, Luciano Boquete, Román Blanco (SPAIN)
P30
Using a novel electrode based on a super absorbent polymer for preparation-free recording of visual evoked
potentials
Susanne Kramer, Torsten Strasser, Tobias Peters, Eberhart Zrenner (GERMANY)
P31
Recording the steady-state pattern ERG responses using lock-in amplifier
Kazuma Yagura, Soiti Matsumoto, Kei Shinoda, Harue Matsumoto, Atsushi Mizota (JAPAN)
P32
Grouped responses of multifocal visual evoked potentials and their sensitivity in the detection of simulated
visual field defects
Maja Šuštar, Jelka Brecelj (SLOVENIA)
14:30 – 15:30
Poster session 2 – Retinal diseases – Poster/Second foyer
Moderators: Ruth Hamilton, Mineo Kondo, Serge G. Rosolen
P33
A case of peripheral cone dystrophy with different cone dysfunction on each eye
Rei Arai, Yujin Mochizuki, Nobuo Ishida, Atsushi Mizota, Nobuyuki Ebihara (JAPAN)
P34
Electroretinographic follow-up in cone and cone–rod dystrophies
Cornelia Andreea Corici, Maja Šuštar, Martina Jarc-Vidmar, Branka Stirn-Kranjc, Marko Hawlina, Jelka Brecelj
(SLOVENIA)
P35
Retina-wide disease and foveal sparing in ABCA4-related retinopathy
Ana Fakin, Anthony G. Robson, Kaoru Fujinami, Anthony T. Moore, Andrew R. Webster, Michel Michaelides, Graham E.
Holder (UNITED KINGDOM)
P36
Clinical and genetic characteristics of a Japanese family with autosomal dominant retinitis pigments
Miki Hata, Kaoru Fujinami, Takeshi Iwata, Toru Noda, Kazushige Tsunoda (JAPAN)
P37
Characteristics of global flash mfERG in patients with retinitis pigmentosa
Christie Hang I Lam, Serena Zhe Chuang Li, Man Pan Chin, Henry Ho Lung Chan (HONG KONG)
P38
Foveal hypoplasia and atypical retinitis pigmentosa in a family: clinical phenotype and genetic investigations
Ajoy Vincent, Heather Macdonald, Jeffrey Locke, Anupreet Tumber, Carol Westall, Elise Heon (CANADA)
P39
Clinical and electrophysiological findings in two siblings with mutations in the USH2A gene
Eva Lenassi, Maria Bitner-Glindzicz, Linda M. Luxon, Graham E. Holder, Andrew R. Webster, Anthony G. Robson (UNITED
KINGDOM)
xiv
P40
Analysis of patients with electronegative b-waves (2008–2014): a case series
Ranjana Mathur, Li Yu Chen, Rena Png, Gemmy Cheung Cm, Audrey Chia (SINGAPORE)
P41
Geographic atrophy secondary to age-related macular degeneration: functional and morphological evaluation
Elisabetta Pilotto, Evelyn Longhin, Francesca Guidolin, Enrica Convento, Alma Patrizia Tormene, Edoardo Midena (ITALY)
P42
Autoimmune retinopathy in the fellow eye 10 years after initial presentation
Takehito Iwase, Yosuhe Nakamura, Gen Miura, Hisao Ode, Atsuhiro Kanda, Wataru Saito, Shuichi Yamamoto (JAPAN)
P43
Maculopathy following exposure to visible and infra-red laser radiation
James Hanson, Julian Sromicki, Mario Mangold, Matthias Golling, Christina Gerth-Kahlert (SWITZERLAND)
P44
Clinical and electrodiagnostic findings in a family with autosomal dominant RGR mutation
Monique Leys, J. Vernon Odom, Xinjing Wang (UNITED STATES)
P45
Why am I losing my vision? LORD or something else. A case report
Rena Png, Ranjana Mathur, Edmund YM Wong (SINGAPORE)
14:30 – 15:30
Poster session 2 – Animal electrophysiology – Poster/Second foyer
Moderators: Ruth Hamilton, Mineo Kondo, Serge G. Rosolen
P46
Comparison of waveforms of the scotopic threshold response elicited by different methods of stimulation
Takako Hidaka, Hideki Chuman, Nobuhisa Nao-I (JAPAN)
P47
Pivotal roles of Fezf2 in differentiation of cone OFF bipolar cells and functional maturation of cone ON bipolar
cells in retina
Yujin Mochizuki, Atsushi Mizota, Sumiko Watanabe, Nobuyuki Ebihara (JAPAN)
P48
Assessment of the pupillary light reflex in monkey using a new portable device designed for clinical use
Serge Rosolen, Nadège Sarrazin, Youssef Lourhzal, Pierre Moissonnier, Sophie Gilardeau, Cedric Lamirel, Pierre Pouget,
Jean Lorenceau, Anne Baron-Van Evercooren, Serge Picaud (FRANCE)
14:30 – 15:30
P49
Poster session 2 – Retinal function and structure – Poster/Second foyer
Moderators: Ruth Hamilton, Mineo Kondo, Serge G. Rosolen
»En face« spectral domain optical coherence tomography compared with functional tests in patients treated
with anti-malarial drugs
Carl Arndt, Mathieu Costantini, Sylvie Berthemy, Alain Ducasse, Christophe Chiquet, Martine Mauget (FRANCE)
P50
Multimodal imaging of a case of peripheral cone dystrophy
Shuhei Kameya, Naoko Ito, Kiyoko Gocho, Takaaki Hayashi, Sachiko Kikuchi, Satoshi Katagiri, Tamaki Gekka, Kunihiko
Yamaki, Hiroshi Takahashi, Hiroshi Tsuneoka (JAPAN)
P51
Simultaneous recording of electroretinography and visual evoked potential in normal subjects and patients with
vitreous hemorrhage
Young-Hoon Ohn, Tae Kwann Park, Hoon Dong Kim, Yoon Kyung Kim, Jung Woo Han (REPUBLIC OF KOREA)
P52
The effect of sustained bedrest and hypoxia on electroretinographic responses
Maja Potrč, Maja Šuštar, Polona Jaki-Mekjavić, Marko Hawlina, Ola Eiken, Igor Mekjavić (SLOVENIA)
P53
Screening of cone dysfunction by the RETeval (TM) handheld ERG device
Soichiro Tamaki, Natsuko Nakamura, Kaoru Fujinami, Yoshinobu Mizuno, Toru Noda, Yozo Miyake, Kazushige Tsunoda
(JAPAN)
15:30 – 16:00
Coffee break
16:00 – 18:15
Paper session 4 – Methodological aspects of electrophysiology – Oral
Moderators: Daphne L. McCulloch, Michael Bach
16:00
Plagiarism dangers lurking in scientific publishing
Michael Bach (GERMANY)
16:15
Effect of shorter dark-adaptation on ISCEV standard ERGs and an exploration of the dark-adapted red flash ERG
Ruth Hamilton, Kirsten Graham (UNITED KINGDOM)
16:30
Comparison between two types of skin electrode ERG recording system
Atsuhiro Tanikawa, Iyo Ueda, Ryota Sakurai, Yoshiaki Shimada, Masayuki Horiguchi (JAPAN)
16:45
Effect of cataract on flicker electroretinogram (ERG) recorded with RETeval
Takayuki Koike, Yosuke Nakamura, Junki Azuma, Yumi Tanaka, Gen Miura, Takeshi Sugawara, Shuichi Yamamoto (JAPAN)
xv
17:00
Functional imaging of the retina with multi-angular electroretinography (maERG)
Antoine Brassard Simard, Mathieu Gauvin, Bing Yu Chen, Pierre Lachapelle, Jean-Marc Lina (CANADA)
17:15
Effect of pupil size on flicker ERGs recorded with RETeval System: experiments using mydriatics and artificial
pupils
Mineo Kondo, Kumiko Kato, Masahiko Sugimoto, Kengo Ikesugi, Hisashi Matsubara (JAPAN)
17:30
Comparison of constant luminance (cd•s/m2) versus constant retinal illuminance (Td-s) stimulation in the
flicker ERG
Quentin Davis, Olga Kraszewska, Colette Manning (UNITED STATES)
17:45
The topography of spatial-frequency tuning of the steady-state pattern-onset VEP
Sven P. Heinrich, Lisa Herold, David J. Marhöfer, Michael Bach (GERMANY)
18:00
iSim: a smart ERG signal generator for calibration of instruments and alignment of recording regimes across
clinical laboratories
Anthony C. Fisher, Rasam Teymouri, Matthew Elt (UNITED KINGDOM)
18:15
Group photo
Friday, June 26, 2015
Linhart hall
09:00 – 10:45
Paper session 5 – Toxicology and treatment – Oral
Moderators: Karen Holopigian, Mitchell Brigell
09:00
Contribution of the wide field imaging in the screening for Vigabatrin related retinopathy
Carl Arndt, Kim Vardi, Jacques Motte, Nathalie Bednarek, Joseph Bursztyn, Alain Ducasse, Catherine Brugniart
(FRANCE)
09:15
Diagnostic methods in ocular argyrosis
Monika Sarnat-Kucharczyk, Ewa Mrukwa-Kominek, Dorota Pojda-Wilczek (POLAND)
09:30
Multifocal ERG in eyes subjected to inverted ILM flap technique for treating macular hole
Masayuki Horiguchi, Yoshiaki Shimada, Mitsuo Sugimoto, Atsuhiro Tanikawa (JAPAN)
09:45
ERG findings after one year intravitreal ranibizumab and single or multiple spot panphotocoagulation treatment
for proliferative diabetic retinopathy
Katharina Messias, Rafael De Montier Barroso, Fabiano Sakamoto, Vinicius Castro, Amanda Marega, Rodrigo Jorge,
Andre Messias (BRAZIL)
10:00
Functional outcome in prospective intravitreal bevacizumab treatment of macular edema secondary to central
retinal vein occlusion
Ivana Gardašević Topčić, Maja Šuštar, Marko Hawlina, Polona Jaki Mekjavić (SLOVENIA)
10:15
Neuroprotective effect of angiotensin receptor blockers and angiotensin converting enzyme inhibitors, used for
high blood pressure, on the retina of diabetes mellitus type 2 patients studied by mfERG
Graciela Garcia Briones, Mario Alberto Rendon M, Bruno Estañol Vidal (MEXICO)
10:30
Multifocal ERG before and after pars plana vitrectomy in ILM peeling – one-year follow-up
Andre Messias, Ana Claudia De Lucca Perches, Felipe Almeida, Katharina Messias, Rodrigo Jorge (BRAZIL)
10:45 – 11:15
Coffee break
11:15 – 13:00
Paper session 6 – Retinal diseases – Oral
Moderators: Alma Patrizia Tormene, Vernon Odom
11:15
The clinical and electrophysiological features of unilateral pigmentary retinopathy
Anthony G. Robson, Marie-Helene Errera, Tracy Wong, Philip G. Hykin, Bishwanath Pal, Mandeep S. Sagoo, Carlos E.
Pavesio, Anthony T. Moore, Andrew R. Webster, Graham E. Holder (UNITED KINGDOM)
11:30
Electrodiagnostic testing facilitates the identification of two novel retinal dystrophy genes: a new paradigm for
disease gene discovery
Panagiotis I. Sergouniotis, Anthony G. Robson, Uwe Wolfrum, Eva Lenassi, Ucl-Exomes Consortium , Martin Mckibbin,
Manir Ali, Vincent Plagnol, Andrew R. Webster, Graham E. Holder (UNITED KINGDOM)
xvi
11:45
Japan whole exome project for inherited retinal diseases 2014
Kaoru Fujinami, Takaaki Hayashi, Kazuki Kuniyoshi, Mineo Kondo, Shinji Ueno, Kei Shinoda, Kazuo Tsubota, Yozo Miyake,
Kazushige Tsunoda, Takeshi Iwata (JAPAN)
12:00
ERG in Slovenian patients with Usher syndrome
Ana Fakin, Martina Jarc-Vidmar, Branka Stirn Kranjc, Maja Šuštar, Jelka Brecelj, Marko Hawlina (SLOVENIA)
12:15
Interesting phenotype and electrophysiological findings in Slovene family with ABCA4 mutation
Martina Jarc-Vidmar, Ana Fakin, Maja Šuštar, Jelka Brecelj, Branka Stirn-Kranjc, Damjan Glavač, Marko Hawlina
(SLOVENIA)
12:30
Inner retinal dysfunction at the macula in patients with ‘macula-on’ rhegmatogenous retinal detachment
Kunihiko Akiyama, Kaoru Fujinami, Ken Watanabe, Natsuko Nakamura, Toru Noda, Yozo Miyake, Kazushige Tsunoda
(JAPAN)
12:45
Retinal dystrophy with supernormal and delayed rod ERG b-waves: a possible explanation
John Robson (UNITED STATES)
13:00 – 14:30
Lunch
14:30 – 16:00
Paper session 7 – Animal electrophysiology – Oral
Moderators: Pierre Lachapelle, Mathias W. Seeliger
14:30
Introductory lecture: Oxidative retinopathies in neonatal rats: subtle onset with long-term devastating
consequences
Pierre Lachapelle, Anna Polosa, Allison L. Dorfman, Samaneh Chaychi, Xiaojuan Yang (CANADA)
15:00
Bright light exposure in photoreceptor-only rodent model: unexpected findings
Anna Polosa, Suna Jung, Fares Antaki, Hyba Bessaklia, Pia Wintermark, Pierre Lachapelle (CANADA)
15:15
Silent substitution isolation of rod and cone function in mice transgenic for human L-opsin
Tina Tsai, Jenny Atorf, Maureen Neitz, Jay Neitz, Jan Kremers (GERMANY)
15:30
Sildenafil as a potential therapy for visual impairments associated with birth asphyxia: a rat study
Suna Jung, Zehra Khoja, Aaron Johnstone, Pierre Lachapelle, Pia Wintermark (CANADA)
15:45
Modulating of ocular inflammation with macrophage migration inhibitory factor is associated with notch
signaling in experimental autoimmune uveitis
Bo Lei, Hongxia Yang, Shijie Zheng, Yingying Mao, Hongwei Li, Zihe Chen (CHINA)
16:00 – 16:15
Coffee break
16:15 – 17:45
Membership meeting
19:00 – 20:00
Adachi award lecture
Metabolic disease with choroidal atrophy: gyrate atrophy and LCHADD
Richard Weleber (UNITED STATES)
Introduction: Colin Barber (UNITED KINGDOM)
20:00 – 23:00
Conference dinner (Club CD)
xvii
Saturday, June 27, 2015
Linhart hall
09:00 – 10:45
Paper session 8 – Retinal function and structure – Oral
Moderators: Mary Johnson, Audrey Chia Wei Lin
09:00
Evidence for an asymmetrical effect of type 1 diabetes on retinal structure and function
Thomas Wright, Alan Poon, Ahmed Salem, Carol Westall (CANADA)
09:15
Comparing the retinal structure, function and biochemistry in a animal model of spontaneous diabetes
Serge Rosolen, Sylvie Lavillegrand, Stephanie Lafarge-Beurlet, Pierre-Francois Isard, Charles Cassagnes, Thomas
Dulaurent, Serge Picaud, Patricia Crissanti, Marianne Berdugo (FRANCE)
09:30
Assessment of macular function and structure in patients with idiopathic epiretinal membrane treated by pars
plana vitrectomy
Wojciech Lubiński, Wojciech Gosławski, Leszek Kuprjanowicz, Karol Krzystolik, Maciej Mularczyk (POLAND)
09:45
Unmasking ERG ON-OFF interactions with the discrete wavelet transform (DWT)
Mathieu Gauvin, Maja Šuštar, Jean-Marc Lina, John M. Little, Robert K. Koenekoop, Pierre Lachapelle (CANADA)
10:00
Does flicker ERG depend on stimulus color?
Olga Kraszewska, Quentin Davis, Colette Manning (UNITED STATES)
10:15
Correlation between macular cone density and focal macular electroretinogram in normal eyes
Hiroko Terasaki, Kennichi Kawano, Yasuki Ito, Taro Kominami, Shinji Ueno (JAPAN)
10:30
When function, structure and electrophysiology don’t agree
Michael Marmor (UNITED STATES)
10:45 – 11:15
Coffee break
11:15 – 12:00
Dodt and Marmor award
12:00 – 12:10
Closing ceremony
12:15 – 13:30
Lunch
15:00 – 21:00
ISCEV Olympics and picnic at lake Bled
xviii
INFORMATION FOR SPEAKERS AND POSTER PRESENTERS
Poster presentations
Posters will be displayed in Foyer II. Display boards will be numbered. Presenting authors are requested to be
available for discussion next to their posters during the scheduled time. Posters will be displayed all the time
during the congress. Cankarjev dom is not responsible for any poster left behind at the end of the day.
Speakers’ Centre
The technical organizer will give you additional instructions concerning your session and the presentation
of your paper in the Speakers’ Centre. The Congress staff will ensure that your presentation is downloaded
on the computer in your specific session room. Please make sure that your computer presentation is fully
operational before your talk. Only Power Point presentations, CDROM, ZIP disk USB1 Memory cards will be
accepted. Version MS PowerPoint 2007 is recommended. We recommend installing and testing your computer
presentation at least two hours before your talk. A technician and a room attendant will be in every room to
provide assistance when needed.
The Speakers’ Centre will have the same opening hours as the registration desk.
Internet
Wireless internet connection is available in Foyer II. The name of the network is CDWLAN. No login or
password is required.
REGISTRATION AND FEES
Participant’s registration fee includes:
•
Participation in all lectures •
Congress bag including programme and abstract book
•
Electronic Abstract Book
•
Certificate of Attendance
•
Welcome Reception •
Coffee during breaks
•
Lunches
•
Conference Dinner
•
Sports Game & Outdoor Party at Bled
The registration fee for Accompanying Person’s includes:
•
Welcome Reception / Wednesday, June 24
•
Sightseeing of Ljubljana / Thursday, June 25, 10.00–12.00
•
Excursion to Postojna and Predjama Castle - half day/ Friday, June 26, 9.00–14.30
•
Conference Dinner / Friday, June 26, 20.00–24.00
•
Sports Game & Outdoor Party at Bled / Saturday, June 27, 15.00–19.00
Registration and Information Desk
The ISCEV 2015 Registration Desk is located in Foyer II of Cankarjev dom and is open as follows:
Wednesday, June 24
17.00–20.00 Thursday, June 25
8.00–19.00 Friday, June 26
8.00–19.00
Saturday, June 27
8.00–14.00
xix
SOCIAL PROGRAMME
WEDNESDAY, JUNE 24, 2015
20.00–23.00 Welcome Reception/Ljubljana Castle
Included in the fee for participants and accompanying persons.
Meeting point: 19.45 at Cankarjev dom, Erjavčeva Street (by bus), returning at 23.00
Please note that you can take a funicular train to the Ljubljana Castle.
Price:
• Return ticket à EUR 4.00
•
Single ticket à EUR 2.20
FRIDAY, JUNE 26, 2015
20.00–23.00 Conference Dinner/Cankarjev dom – CD Club
Included in the fee for participants and accompanying persons.
xx
SATURDAY, JUNE 27, 2015
15.00–21.00 Sports game and Outdoor Party at Bled
Included in the fee for participants and accompanying persons.
Meeting point: 14.45 at Cankarjev dom, Erjavčeva Street (by bus), returning at 21.00
GENERAL INFORMATION
Conference Identification Badge
A conference identification badge will be included in the conference material provided at registration. There
will be no admittance to the Scientific Sessions without the conference badge. Invitations to social events will
be collected at the entrance.
Attendance Certificate
A Certificate of Attendance will be issued to all registered participants.
Coffee Breaks
During breaks, refreshments will be served free of charge to participants wearing congress badges.
Lunches
Working lunches (standing buffet) are included in the registration fee and will be served at lunchtime in Foyer II.
xxi
RETImap animal®
ABSTRACTS
……………
Scanning laser ophthalmoscope and modules:
mfERG
GFP
VEP
OCT
Angiography
xxiv
3 Friedrich-Franz-Str.19,
D-14770 Brandenburg/Germany, www.roland-consult.de
ROLAND
CONSULT
Electrophysiological diagnostic systems
M
Operator unit
Macula Module
Ganzfeld ERG
AUTHOR’S INDEX
Stimulator Monitor
2,5µV/div
RETImap® Model 520
R
Electrophysiology & Imaging for Retina Diagnostic
25 ms/div
VEP
ALL IN ONE
peak time
(t)
Dark-adapted 0.01 ERG
b-wave: rod-initiated
on pathways
Dark-adapted 3.0 ERG
a-wave: photoreceptors
& postreceptoral on
pathways b-wave:
on & off bipolar cells
b
a
t
Dark-adapted 10.0 ERG
a-wave: photoreceptors
& postreceptoral on
pathways b-wave:
predominantly rod bipolar cells (on pathways)
mfERG
b
a
t
Dark-adapted 3.0
oscillatory potentials
On & off pathways
reflecting middle
retinal layers & vascular
function
cSLO
b
Light-adapted 3.0 ERG
a-wave: cones with
post-receptoral on & off
pathways b-wave: on &
off bipolar cells
VEP
a
t
Light-adapted 3.0 flicker
Cone systems with
post-receptoral on & off
pathways
b
N
e
OCT
c
a
d
ON-OFF response
b
i
a
Angiography
Friedrich-Franz-Str.19, D-14770 Brandenburg/Germany, www.roland-consult.de
4
PhNR
PhNR response
ROLAND
CONSULT
Electrophysiological diagnostic systems
xxv
RETIcompact II®
OGLASI
C
Electrophysiological Diagnostic for Macula, Retina and Diabetic
ALL IN ONE
nostic for Macula
g
a
i
, Re
d: D
r
tin
a
d
n
aa
a
t
n
S
mfERG
dD
etic
iab
ISC
EV
mfERG 3D-plot
VEP
ERG
os
tic
Too
l!
EOG
Special tools for children:
MINIganzfeld
je
Your Ob
Pattern Handheld
ia
D
e
ct i v
gn
BABYflash
Friedrich-Franz-Str.19, D-14770 Brandenburg/Germany, www.roland-consult.de
xxvi
Visual
Acuity
Glaucoma
Screening
Pupillometry
ROLAND
CONSULT
Electrophysiological diagnostic systems
ROLAND DARKadaptometer
and Pupillometer
H
ita
d
e
er
inopathies . Immune
t
e
r
&
ry
I nf
am
D
ma
e
ry
to
Patients view
ye
ases
dise
to
ret
ino
toxi
c ag
ents
Normal patient
u
os
re
M
e ta
bo l
ic d
ncy
e
i
isord
c
ers . Vitamin A-Def
. Ex
p
Friedrich-Franz-Str.19, D-14770 Brandenburg/Germany, www.roland-consult.de
Pupillometry measurement
Specifications:
. Maximum bleaching luminance between
6500 - 7000 cd/m²
. Stimulus spot colors: red (625nm)
and green (527nm)
. Maximum spot brightness 250 cd/m²
. Minimum spot brightness 2.5 * 10-8 cd/m²
. Fixation target brightness: 50
. Stimulus impulse with a PWM of 225Hz
. Stimulus spot size: 2°
. Fixations: Center (5°), 10°, 20°(default), 30°, 40°
ROLAND
CONSULT
Electrophysiological diagnostic systems
xxvii
leading the wave
Welcome to ISCEV!
Introducing the ColorLens: a compact,
high-throughput ERG solution for mice
• Reproducible results
• Runs various phenotyping protocols
• Simple to use
xxviii
Come see our full suite of
electrophysiology systems
• ERG
• EOG
• PERG
• Flash VEP
• Pattern VEP
• Multifocal/Focal
• Dark Adaptometry
• Pupillometry
xxix
RETeval
TM
www.lkc.com
Visual Electrodiagnostic System – like having your current flash based system in the palm of your hand
•
•
•
•
•
•
•
•
Fully ISCEV compliant – Flash ERG – Flash VEP
Non-mydriatic ‒ patented dynamically controlled flash intensities utilizing pupilography
Non-invasive skin electrodes or traditional corneal electrodes ‒ your choice
Fixed flash intensities or troland base flash intensities per the ISCEV protocol for dilated eyes - your choice
Hand-held ‒ easy to use ‒ easy to learn ‒ comprehensive reporting ‒ outstanding performance
Easy to create custom protocols
Innovative file structure retains all raw data on each test for easy and comprehensive analysis ‒ researcher’s dream
A clinically validated diabetic retinopathy (DR) and clinically significant macular edema (CSME) protocol is available in the RETeval
Complete system from LKC, or in standalone form exclusively through Welch Allyn® as Welch Allyn® RETeval - DRTM.
Easy to Use
• Instant results displayed on screen
• Built-in pupillometry adjusts flash
and background intensity, enabling
testing without pupil dilation
• Single electrode array is placed on skin for
each eye (Patent Pending)
• IR camera allows visualization of eye during
test
• Simple joystick control
• Multi-lingual user interface
• Fixation LED for the patient
• Blink and electrode-disconnected detection for more
reliable results
• Built-in photometer ensures correct brightness and color of
stimulation
• EMR interface available
• Reports viewable on the device or on a PC using the USB interface in the base unit
Available in two separately priced configurations:
DR/CSME Assessment using skin Electrodes: The Welch Allyn® RETeval – DR
, manufactured by
LKC Technologies for Welch Allyn®, is available exclusively through Welch Allyn® outside of the United States.
TM
OR
RETeval complete option: In addition to the flicker and DR testing, the complete option enable ISCEV-compliant 5
and 6 step protocols, flash VEP, photopic negative response, s-cone, and much more! Use the LKC Sensor Strip skin electrode
[95-068] or, with an optional adapting cable, you can use any electrode type.
This project described was supported by Award Number R44EY021121 from the National Eye Institute. The content is solely the responsibility of LKC and does not
necessarily represent the official views of the National Eye Institute of the National Institutes of Health.
The device is CE Marked and licensed for sale in Canada, Australia, Japan, Israel and Saudi Arabia. In the United States, it is currently available for research investigational
use only under IRB approval and control.
The device may be covered by one or more of the following US patents and their foreign counterparts: 7,540,613. Additional patents are pending. RETeval™ and RETeval
– DR™ are registered trademarks of LKC Technologies, Inc. Welch Allyn is a registered trademark of Welch Allyn, Inc. RETeval™ is a registered trademark in the following
countries:
xxxCanada, China, Japan, Mexico, Russian Federation, South Korea, Brazil, the E.U. and the United States of America.
COSTRUZIONE STRUMENTI OF TALMICI
RETIMAX
ADVANCED
E ADVANCED PLUS
RETIMAXBASIC,
ADVANCED
& ADVANCED
PLUS
Conform toPERG
ISCEV
standardTest
(International Society for Clinical
Glaucoma
Hemifield
Electrophysiology of Vision) Compact and user friendly RETIMAX.
Diagnosi precoce del Glaucoma.
Useful for the functional assessment of retina, ganglion cells and Optic
Database normativo correlato all’età per i
Nerve. RETIMAX plus COBRA fundus camera adds new attractive
test
ERG, PERG, VEP, EOG.
feature at the Multifocal ERG, PERG and VEP, the combination
Vision
Trainer
Riabilitazione
visiva
Between
Multifocal
ERG and photographic
image of the Retina.
Biofeedback
Via degli Stagnacci 12/E
50018 Scandicci, Firenze (Italy)
Tel. ++39 055.722191 – www.csoitalia.it
ELECTROPHYSIOLOGY EP-1000
Standardised, compact
and multifunctional.
LED colour flash and
background illumination
Programme editor for
individual examinations
Multifocal ERG
ISCEV conform standard tests
S-Cone analysis, PERG Ratio
EP-1000 Multifocal
Normal data overlay
Measurement display
PERG Ratio
VEP Children ext.
TOMEY GmbH | Am Weichselgarten 19a | 91058 Erlangen, Germany | Phone +49 9131 777 10
Fax +49 9131 777 1 20 | Email info@tomey.de | www.tomey.de
xxxii
xxxiii
EXHIBITION PLAN
NOTES
NOTES