The StethoSCOOP - University of Cincinnati College of Medicine
Transcription
The StethoSCOOP - University of Cincinnati College of Medicine
UCMC INTERNAL MEDICINE The StethoSCOOP RESIDENCY V O L U M E 3 , I S S U E 8 A U G U S T 7 , 2 0 1 5 Weekly Calendar SPECIAL POINTS OF INTEREST: 8/10: Noon Report: Yellow team Research Pathway High Yield 8/11 Noon Report: Red Team Review! Neurohormonal what? 8/12: Grand Rounds: Anumeha Gupta, MD: “Incorporating palliative care in Oncology: A new paradigm in comprehensive cancer care 8/13: Weesner Prep: Anemia with Courtney Academic Half-Day: High Yield Topics with Dr. Mathis Optimizing care of patients with Sickle Cell 8/14: Intern and Senior Noon Reports: Heme/Onc Team Big thanks to Dr. Warm and his family for providing for an awesome ice cream social. Thanks to everyone who turned out to enjoy it! Suggestions for next month? Disease INSIDE THIS ISSUE: Heart Failure 2 NO SPORTS 2 Hyponatremia 3 Board Review 4 Sickle Cell Updates 4 Weekend to-do 6 Medical Trivia 6 Shoutouts 6 Anonymous Feedback Our website has a section for anonymous feedback. Think of this like an electronic suggestion box that you can use at any time. The message will be sent directly to Dr. Warm, and is completely anonymous. If you have constructive feedback that you would like to share, please use this tool. The link is: http://intmed.uc.edu/education/residency/feedback.aspx VOLUME 3, ISSUE 8 PAGE Heart Failure QUICK HITS! 1. Quick hemodynamic assessment 2. Neurohormal pathophysiology model 3. 5 things you can do for the heart No sports this Sunday, but start preparing for the annual RESIDENT v. FACULTY SOCCER game. Look to take the field sometime in September. THE STETHOSCOOP 2 VOLUME 3, ISSUE 8 PAGE 3 Hyponatremia! Plasma Na+ concentration is a measure of concentration and NOT of VOLUME Disorders of plasma sodium concentration reflect an underlying disorder involving water homeostasis: an impaired ability of the kidneys to excrete free water due to the action of ADH Urine Osmolarity: the appropriate response to hypo-osmolar serum (<275) is to excrete a maximally dilute urine (Uosm <100); non-dilute urine (Uosm> 100) is evidence of impaired free water exchange via appropriate or inappropriate ADH Urine Na: appropriate renal response is to enhance Na reabsorption (UNa <10); when UNa >20– evidence of either normal effective circulating volume or an intrinsic Na-wasting problem Hyponatremia. Horacio J. Adrogué, M.D., and Nicolaos E. Madias, M.D. N Engl J Med 2000; 342:1581 -1589May 25, 2000DOI: 10.1056/NEJM200005253422107 THE STETHOSCOOP VOLUME 3, ISSUE 8 PAGE 4 BOARD REVIEW WITH THE CHIEFS DUST OFF THOSE OLD STETHOSCOPES, FOLKS. IT’S TIME TO START GEARING UP FOR BOARDS. HERE IS A QUICK PEARL WE LEARNED THIS WEEK: Q: 76 y/o female is admitted for a 1-week history of progressive weakness, nausea, and anorexia. She lives independently but has become bedridden and confused during the past 3 days. Her past medical history is notable for hypertension for which she takes enalapril and chlorthalidone, which was started 2 weeks ago. Physical exam and laboratory studies are consistent with hypotonic hyponatremia with a serum sodium of 111 meq/L. Therapy with 3% saline initiated and her mentation rapidly improves to baseline. Repeat labwork 10 hours later reveals the following: Serum Na of 121, Urine Na of 48 (from 82 on admission), Urine osmolality of 206 (from 486 on admission) and a urine output of 400mL/h since admission. What is the next most appropriate treatment? 5% dextrose in water. This patient has hypotonic hyponatremia associated with altered mentation, which typically warrants prompt correction with 3% saline. However, the increase in her serum sodium level following treatment exceeds the recommended initial target of 4 to 6 meq/L (4-6 mmol/L) over the first 24 hours. The high urine volume and decreasing urine osmolality following hypertonic saline administration reflect a rapid water diuresis and suggest that the serum sodium level will likely continue to increase, placing the patient at increased risk for osmotic demyelination syndrome (ODS). Therefore, hypotonic solutions such as 5% dextrose in water should be administered with close follow-up of the serum sodium level, with the goal of maintaining the serum sodium level in the range of 114 to 116 meq/L (114-116 mmol/L) in the first 24 hours. Sterns RH, Hix JK. Overcorrection of hyponatremia is a medical emergency. Kidney Int. 2009;76 (6):587-589. PMID: 19721422 Sickle Cell Care Updates 1. Watch for Epic patient alerts describing individualized care plans unique to some patients 2. The recommended safe maximum bolus of IV hydromorphone is 2mg every 30 minutes for up to 4 doses 3. Keep an eye out for a new and improved order set coming soon. Please direct questions about care of patients with Sickle Cell Disease at UCMC to Dr. Hyon Kim at kim2ho@ucmail.uc.edu. THE STETHOSCOOP VOLUME 3, ISSUE 8 PAGE 5 Weekend To-Do: Aug. 7-9: Lumenocity, 4-11 p.m. Friday, 3-11 p.m. Saturday, 3-11 p.m. Sunday, Washington Park, 1230 Elm St.,Over-the-Rhine. Live illuminated concert experience. Features music, new animations, LumenoCity Village and more. Show tickets are sold out. 513-744-3372; lumenocity2015.com. Aug. 7: Shakespeare in the Park, 7 p.m., Cottell Park, 5847 Irwin Simpson Road,Deerfield Township. New production of “Romeo and Juliet.” Bring lawn chairs or blankets. Presented by Cincinnati Shakespeare Company. Free. 513-683-5805;www.cincyshakes.com. Aug. 8-9: Slide the City, 9 a.m. Saturday-Sunday, University of Cincinnati, 2624 Clifton Ave., University Heights. Event organizers set up 1,000-plus feet of padded vinyl to transform city into one giant party. Food vendors and live music. $45, $40 advance. Spectators free. No phone; www.slidethecity.com. Aug. 8: Northside Second Saturdays, noon-midnight, Hamilton Avenue, Northside. Promotional deals, art, exhibits, fashion, food and music. Free. 513-721-0200. Aug. 9: Second Sunday on Main, noon-5 p.m., Main Street, 14th and Main streets, Over-theRhine. Street fair on Main featuring craft and food vendors, entertainment, demonstrations and more. EcoMAINia. Free. 513-910-8845; www.secondsundayonmain.org. TRIVIA How does the compound derived from the plant at right execute its mechanism of action? Congratulations to Leslie Applegate for identifying mycosis fungoides! First correct answer to Stephen wins a Starbucks or Copper Moon gift card! SHOUT OUTS!!! (Let us know who Rocks) -Shout out to Leila Borders for doing awesome work as our nocturnal cardiology resident this past week! -Shout out from the AOD: night float seniors for making an AOD's job easy? Robin Wright, Darek Sanford, and Denada Palm were great and we ran some smooth rapids together last weekend. Thanks! -Shout out to Cody Lee for running his first code ever like a boss. THE STETHOSCOOP