Tufts University School of Medicine
Transcription
Tufts University School of Medicine
MAGAZINE OF THE TUFTS UNIVERSITY MEDICAL AND SACKLER ALUMNI ASSOCIATIONS VOL. 66 NO. 1 MEDICINE Have we gone too far with hygiene? P L U S : A M U S TA C H E C O N T E S T ■ PERUVIAN RESCUE ■ MY TEXAS HOME WINTER 2007 V I TA L S I G N S Type cast APPARENTLY THE FIRST PERSON TO USE THE MANUAL TYPEWRITER AS A MUSICAL instrument was American composer Leroy Anderson, who featured the clackety, dinging office machine in a piece he wrote back in 1950. The Boston Typewriter Orchestra, a five-member ensemble of graduate students and their pals, is building on what they call that “cheerful and enjoyable” historic moment and carrying its promise forward through their antic performances of keyboard syncopation. The birth of the BTO came a couple of years ago in a barroom. Tim, one of the original members, was idly tapping out a rhythm on a kid’s typewriter in time to some tune playing on the radio. When a waitress asked him to desist, he replied that it was OK because he was, after all, the conductor of the Boston Typewriter Orchestra. His improvised claim soon became the level truth. Alex Holman, 27, a doctoral student in genetics at the Sackler School of Graduate Biomedical Sciences, signed on about a year ago. He is plainly a natural at it. Asked to describe his favorite instrument of the 15 or 20 vintage machines that the BTO keeps on hand—typewriters generally found after being discarded somewhere along the road—he replies, “I do like that Underwood Five model. They have a good, solid bass sound to them.” Other typewriters in the collection tend to ring more in an alto or tenor range, says Holman (below left), a pony- tailed young man with flashing dark eyes and energy to burn. Picture a half-dozen 20-something guys seated around a table, dressed in shirts and ties and whaling away at their machines, with rhythmic patterns repeating like the drumming of fingers on a countertop, and you have the heart of a BTO performance. (For more, see http://go.tufts.edu/typewriter.) The band has seven or eight original compositions that they play, in the process creating a droll tableau of pre-1965 office productivity. It’s the Marx Brothers on company time. The group has performed at street fairs in Worcester and Somerville and at a handful of clubs around Boston, in addition to an appearance on Fox News. What does the group sound like? If their CD, The Revolution Will Be Typewritten, is any clue, they sound like a tap dance, like car keys tossed on a table or like an ice cream truck crossed with machinegun fire. PHOTO: MELODY KO CONTENTS W I N T E R 2 0 0 7 I V O L U M E 6 6 , N O. 1 F E AT U R E S 6 Local hero Barbara Talamo, Ph.D., steps down after 11 years as chair of neuroscience, a department she helped to build from scratch. 8 8 Deliverance by Joseph Donroe, A98, M.D./M.P.H., ’07 This guy became a hero to kids with no future. 15 Close encounters of the healing kind by Lisa Y. Livshin, Ed.D., and Jacqueline Mitchell How Tufts is teaching students to be more effective doctors, one patient at a time. COVER STORY 22 The good worms Dr. Joel Weinstock argues that intestinal parasites may be essential to a healthy human immune system. illustrations by Ken Orvidas 28 Deep in the heart by Lauro F. Cavazos, Ph.D. A former dean of the medical school describes growing up on the King Ranch in Texas. D E PA R T M E N T S 2 Letters 3 From the Dean 4 Pulse I A scan of people and events 34 On Campus 38 University News 40 Beyond Boundaries 44 Alumni News winter 2007 tufts medicine 1 LETTERS MEDICINE WHAT HE TAUGHT I was so saddened to hear about Dr. Ernest Grable’s death (Spring 2006). He is responsible for so many of us from Tufts becoming surgeons. His spirit, humor and dedication to excellent surgical care and teaching were exemplary. I think of him almost daily and remember his teachings, not only about surgery but on how to be a good surgeon and person. He and his wife, Cecily, mentored me in the OR and even on parenting and combining surgical life with home life. He encouraged me to be good at listening, studying, operating and teaching. His spirit, voice and legacy will continue through the thousands of students he taught. kerry bennett, j89, m.d./m.p.h.93, facs attending surgeon, caritas st. elizabeth’s medical center boston, mass. MY TIME IN AFRICA I appreciated the “Letter from Zambia” by Jeffrey Lazar, M.D./M.P.H. ’03, in the recent issue of Tufts Medicine (Summer 2006). I am a Tufts alumnus who went on, after surgical residency and two years in the Army, including Vietnam, to spend 32 wonderful years in Zambia in a rural 200-bed general mission hospital. During those years, HIV arrived about 1986, and several other diseases morphed very noticeably. TB and malaria became progressively resistant to treatment. Deadly African trypanasomiasis quickly and mysteriously vanished from our highly endemic area in the 1980s, and our once-packed leprosy settlement was bulldozed after several years of sitting empty for lack of patients. Africa is at the same time a place of untold hardship and suffering and a wonderland of medical diversity and challenge. Our rural Mukinge Hospital became a referral hospital for six other hospitals in our vast province during my years there. What a privilege it was to make that fascinating journey, and never a dime of malpractice insurance to pay! Thank you for featuring Dr. Lazar’s article. Zambia needs an army like him, but even more, it needs to find a way to keep incountry the medical graduates from Zambia’s own medical school. robert l. wenninger, ’63 cranston, r.i. LOOKING FORWARD I feel I would be remiss if I did not write to congratulate all those involved in the production of Tufts Medicine. It is a magnificent magazine, both in its extremely attractive format as well as in content. The articles span many fields of interest and serve to keep all of the Tufts Medical family informed of the activities of the student body, faculty and alumni. I look forward to each issue. The magazine continues to help continue my bond with the school 52 years after graduation. theodore a. labow, ’55 massapequa, n.y. TALK TO US Tufts Medicine welcomes letters, concerns and suggestions from all its readers. Address your correspondence, which may be edited for space, to Bruce Morgan, Editor, Tufts Medicine, Tufts University Office of Publications, 136 Harrison Ave., Boston, MA 02111. You can also fax us at 617.636.4075 or e-mail bruce.morgan@tufts.edu 2 tufts medicine winter 2007 volume 66, no. 1 winter 2007 Medical Editor Dr. John K. Erban, ’81 Editor Bruce Morgan Editorial Director Karen Bailey Art Director Margot Grisar Designer Betsy Hayes Contributing Writers Marjorie Howard, Jacqueline Mitchell Mark Sullivan Alumni Association President Dr. Betsy Busch, ’75 Vice President Dr. David Wong, ’87 Secretary-Treasurer Dr. David S. Rosenthal, ’63 Medical School Dean Dr. Michael Rosenblatt Executive Council Drs. Joseph Abate, ’62, David Atkin, ’60, Mark Aranson, ’78, Fred G. Arrigg Sr., ’47, Paul Arrigg, ’82, Laurence Bailen, ’93, Henry H. Banks, ’45, Richard A. Binder, ’64, Kenneth E. Blotner, ’64, Leonard M. Bornstein, ’58, Alphonse Calvanese, ’78, Stephen J. Camer, ’65, Gina Ruth Carter, ’87, Barbara A. Chase, ’73, Bart Cilento, ’87, Eric Cohen, ’86, Michael F. Collins, ’81, Jeffery Cooley, ’84, Francis A. D’Ambrosio, ’45, Paul D’Ambrosio, ’88, Giacomo A. DeLaria, ’68, Salvatore A. DeLuca, ’58, Gerard Desforges, ’45, Jane F. Desforges, ’45, Elias C. Dow, ’53, Scott K. Epstein, ’84, John K. Erban, ’81, Emil M. Ferris, ’46, David A. Fisher, ’63, Charles Glassman, ’73, Brian M. Golden, ’65, Sherwood L. Gorbach, ’62, Edward T. Gordon, ’47, Michael A. Gordon, ’76, Thomas R. Hedges, ’75, Joseph L. Kennedy Jr., ’59, Robert Kennison, ’60, Frederic Little, ’93, Kathleen M. Mark, ’80, Philip E. McCarthy, ’59, Bruce M. Pastor, ’68, Richard A. Reines, ’76, Karen Reuter, ’74, Barbara A.P. Rockett, ’57, Robert C. Sarno, ’70, Laura K. Snydman, ’04, Paul Sorgi, ’81, Susan J. Stein, ’85, Elliot W. Strong, ’56, John G. Sullivan, ’66, Gerard A. Sweeney, ’67, James A. York, ’92 Tufts Medicine is published three times a year by the Tufts University School of Medicine, Tufts Medical Alumni Association and Tufts University Office of Publications. Send correspondence to Bruce Morgan, Editor, Tufts Medicine, 136 Harrison Avenue, Boston, MA 02111 or e-mail bruce.morgan@tufts.edu. The medical school’s website is www.tufts.edu/med FROM THE DEAN The next step as we embark on our capital campaign for the medical school, this seems an opportune moment to reflect on where we’ve been, what we’ve become and where our aspirations lie. We have come a long way, but we have a great distance yet to go. Although the chief mission for the medical school at its founding in 1893 was to produce practicing doctors for New England cities and towns, we have long since transcended that simple model. In the 21st century we are engaged in creating a multifaceted brand of medicine that touches and transforms the world. We still turn out our share of excellent, caring physicians, of course. That will always be our hallmark. But in recent years, we have steadily broadened the scope of our mission. In 2007, in addition to fine doctors, we also take pride in creating superb policymakers, MBAs and talented researchers and leaders of academic medicine who will have an impact wherever they are. This is medicine whose meaning and impact extends far beyond the tumbled stone walls of New England. Consider research as one example. Working within the tradition of faculty members Drs. Robert S. Schwartz, whose groundbreaking work on immunosuppression in the 1950s made successful organ transplants possible, and William Dameshek, recognized as one of the founders of modern hematology, our medical school has grown into a powerful research enterprise, with special strength in infectious diseases and microbiology. We have found a critical new role for ourselves in translational research that touches more lives and serves more communities than ever before as we strive to improve human health. The composition of our student body has undergone parallel dramatic shifts. From the start, Tufts Medical School has made an effort to forge classes as diverse as the world our doctors serve. We enrolled women in our first class, giving them the chance to find a satisfying life in medicine at a time when this opportunity was rare for women. Now our classes are approximately half female. Racial diversity is another recurring challenge. Dorothy Boulding Feribee, a member of the Class of 1924, was a granddaughter of slaves who later founded the Mississippi Health Project to provide health care for indigent blacks. We continue to make enrolling well-qualified minorities a goal of our outreach. As I’m sure you know, the challenges we face as a medical school are multiple. We need funds to alleviate the financial pressure on the hospital-based faculty who volunteer to teach our students for little or no remuneration. We need to preserve the studentcentered culture for which we are known by continuing to provide ready access to a rich network of services and facilities for them. We need to resist the tendency to become a school solely for children of privilege by providing more scholarship money for those students we do want to enroll, but who cannot afford the high cost of attending medical school at Tufts. There’s more. As many of our senior faculty members retire over the next decade, we will need to replenish the faculty. We must stay competitive in the packages we offer new faculty if we are to remain in the front rank of American medical schools. This, too, will require enhanced funding. It’s easy to think a capital campaign is all about money. But when you come right down to it, it’s really about people and vision. How do we go from where we are to where we want to be? That’s the question that drives and sustains us in our work. The answers to that question go off in a thousand directions and involve you if you will let them. Tufts University President Lawrence S. Bacow has said that great universities consist of great faculty and great students, and the same is true of medical schools. One example of the sort of extraordinary student that we attract these days is Joseph Donroe, A98, M.D./M.P.H. ’07, whose story appears on page 8 of this issue. Donroe, former captain of the Tufts basketball team and an Academic All-American when he was an undergraduate, has created an organization that addresses the physical and mental health of street children and orphans in Lima, Peru. Over the past two years, during an extended leave of absence from the medical school, he has managed to bring purpose and hope to hundreds of kids who were bereft of both when he arrived. I am proud of the values exhibited by students like Joe Donroe. I am proud of what our school has become and what it aspires to be in the coming years. Won’t you join us as we seek to move to the next level of excellence? Michael Rosenblatt, M.D. winter 2007 tufts medicine 3 PULSE A S C A N O F P E O P L E & EV E NT S Jackie Moss and Michael Hall rev it up at The Kells. Ashwin Sridharan (right) won in the “Sketchiest Mustache” category. Student mustache contest has a philanthropic goal Hair we are malnourished kids adrift in the slums of bombay, india, owe a small debt to students at Tufts Medical School, courtesy of something called the Mustache Bash. Two first-year students, Peter Acker and Pritesh Gandhi, were the co-organizers of the event, which solicited men on the Boston campus, together with their female “coaches,” to compete for tonsorial greatness this fall. Funds raised by the contest have been sent to a site in India to help defray the costs of supplying basic medical services to a population of desperately poor children. The competition was born as a blend of fun and sober purpose. “We thought it was just something novel that people would be entertained by and maybe raise some money for a good cause, too,” said Acker, before admitting, “it’s been more popular than we thought it would be.” Some 60 students paid $10 each to enter the fray. That’s counting the coaches, who played a largely inspirational role. “We didn’t want to leave the women out, since they don’t really grow mustaches,” Acker explained. “The coach is there as an encourager, to offer words of advice and support you in your mustache-growing endeavor.” The final judging was held at The Kells, an Irish bar near Boston University, on the night of October 28. Three volunteer faculty judges—John Castellot, professor of anatomy; Peter Brodeur, associate professor of pathology; and Andrew Wright, professor of microbiology—surveyed the contestants, who each got 30 seconds or so to flash their ’stache and vie 4 tufts medicine winter 2007 for honors in categories ranging from creativity and effort to style and presentation. For his part, co-organizer Gandhi had a luxuriant mustache under cultivation and sounded ready to take the stage when contacted in late October. “Oh, it’s growing,” he said, laughing. “I haven’t shaved for about six weeks now.” Gandhi hadn’t decided what his final look would be—a triple Mohawk, maybe, making full use of his beard?—and quickly referred all such stylistic questions to his coach, Kate Anderson, ’10. Anderson was smiling through it all. “There’s a lot of responsibility—mainly encouraging him not to shave off any facial hair, because he’s getting kind of scrubby,” she joked. Gandhi’s exact mode of presentation was still up in the air two days before the judging. The total receipts for the first-ever ’Stash Bash, counting entry fees and a $5 cover charge assessed at the door, came to about $1,200. Money like that will go a long way in India, said Gandhi, who spent last year in Bombay on a Fulbright grant helping to supply elemental health care to slum residents through the auspices of the Niramaya Health Foundation, a local nonprofit provider. The need for medical intervention is especially acute among children two to six years old, while the costs of this intervention are slight. For less than $2, an Indian child can receive a year’s worth of micronutrient supplementation—meaning that the donation stemming from this one well-groomed event had a shot at covering as many as 600 kids for a year. “That’s significant,” said Gandhi. PHOTOS: MELODY KO NAVAJO TRAGEDY Dr. Cannonball doug brugge, ph.d., associate professor of public health and family medicine, served as editor for a book published this fall that reflects his long engagement with the legacy of uranium mining on Navajo reservations out West. The Navajo People and Uranium Mining (University of New Mexico Press, 2006) charts decades of neglect dating from World War II, when the hazards of uranium exposure on the part of miners and their families were brushed aside in a race to build atomic bombs. “This book is the documented history of how these Navajo people lived, how they worked, and now, sadly, how they died waiting for compassionate federal compensation for laboring in the most hazardous conditions imaginable, and which were known at the time yet concealed from them,” writes Joe Shirley Jr., president of the Navajo Nation. “These Navajo miners and their families became expendable people.” JEFFREY WILLIAM, ’10, PICKED UP A CHE C K I T O U T The website for the medical school has a whole new look and feel. This fall, the school’s Creative Services team, in partnership with University Web Communications, launched a fully redesigned and restructured site at www.tufts.edu/med. Aimed primarily at prospective students, the new site features a dropdown-style navigation menu that simplifies a user’s search for information by grouping content under one of five categories: About Us, Education, Admissions, Research and Clinical Affiliates. Visitors to the site can now readily find the information they want. ILLUSTRATION: ELVIS SWIFT; PHOTO: MELODY KO saxophone at age eight—and two years later, the oboe—and has been playing music ever since. It’s been a good gig. As president of a 20-member jazz ensemble at the University of Pennsylvania, he got the chance to swing and rub shoulders with the likes of Wynton Marsalis, John Scofield and Christian McBride, jazzmen who stopped by campus to give clinics and provide instruction. It’s unusual for a person to master two such differently flavored instruments, but William says he’s found less distinction between the oboe and the sax than between musicians and the rest of the world. “You have to concentrate on listening more than you might otherwise,” is how he puts it. One of the nicest compliments William ever got came when he was in college and had just finished playing a jazz fund-raiser for a senior citizens’ home. A resident approached and asked him who he thought he sounded like. William volunteered that he was a big fan of Cannonball Adderley. “You sound just like him,” said the man. Soft drinks, soft bones middle-age-and-older women may want to limit their consumption of colaflavored soft drinks, suggest the results of a recent study led by Katherine L. Tucker of the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts. Her study linked regular consumption of such beverages with reduced mineral density of hip bones in women past menopause. No similar hip vulnerability to cola appeared in men of the same age. Researchers took bone-density readings at the spine and three sites in the hip for 1,413 women and 1,125 men, all in their 50s and 60s. They correlated the bone data with each individual’s diet patterns and lifestyle factors, including smoking, physical exercise and coffee and alcohol consumption. Tucker’s group reported in the American Journal of Clinical Nutrition that only consumption of cola carried a risk of low bone density. Tucker noted that cola’s health impact could be important, given that carbonated beverage consumption has more than tripled between 1960 and 1990. More than 70 percent of the beverages consumed by participants in the study were colas, which contain phosphoric acid. It’s possible, Tucker said, that low, regular consumption of phosphoric acid, which reacts with calcium in a way that neutralizes the acid, might slowly leach calcium from bone. Men have more bone and calcium to start with, which may explain the gender effect seen in her study. winter 2007 tufts medicine 5 the Builder her voice is temperate and measured, while her eyes hold a peaceful, far-away look, like someone gazing out to sea. “She’s a person who people rely on for her reasoned opinions, even if she doesn’t agree with them,” a colleague observes. “She’s a bridge builder.” Barbara Talamo, 67, professor of neuroscience and physiology, stepped down in July from her 11-year tenure as chair of the neuroscience department. ■ After earning her Ph.D. in biochemistry from Harvard University in 1972, Talamo taught for six years at Johns Hopkins Medical School. Widowed in her first marriage, she has been wed to John Kauer, professor of neuroscience, for the past 21 years. Q: How early did you want to be a scientist? I think that I was always interested in science. My father was a mechanical engineer and inventor, and he loved to fool around making things, fixing things and explaining things, and I liked to be with him. He built crystal radios, and he was interested in astronomy and the stars. He was probably the greatest influence on me in my early years. Q: What were conditions like when you came to Tufts? In 1980, when I arrived, there was a neurology department and a neuroscience lab, but nothing in terms of a real neuroscience research presence. There were a lot of things missing. I decided, with a couple of other people, to make the best of it and build something. In 1981 we started a seminar series. The graduate program began in 1983. And then we were successful in bringing in a big neuroscience grant from the Pew Charitable Trust. They had a competition that was a million-dollar grant, provided the institution matched it, and the focus was on disease. And so we decided to work on Alzheimer’s disease. We came up with a program, and we got the grant, and Tufts Medical School kept the promises that they’d made. We’re ever grateful. Neuroscience became a separate department in 1994. By that time, we had seven or eight faculty and an active graduate program and a very visible research program with national and international recognition. What’s been important for me is the collegial atmosphere I’ve found and the possibility of building an intellectual group and a department in a place that hadn’t planned it that way. The school was very open to recognizing good ideas. Q: Can you describe your own research? I have focused it on regulation by the nervous system of signaling and secretory cells and hormonal cells, and how the history of the signaling alters the function and response of the cells. In recent years, beginning with the work on Alzheimer’s, 6 tufts medicine winter 2007 I began to work on the olfactory system in the nose as a model for looking at Alzheimer’s in the brain. I soon expanded my interest into looking at how nerve cells in the nose detect odor molecules in the air. That’s carried on to a continued interest in a company that my husband and his colleague [Research Assistant Professor] Joel White have set up where they’ve built an electronic nose as a “sniffer” device that can detect molecules in the air the same way dogs do. It began as a project to detect buried land mines. Q: What’s your role in the company? I’m the vice president for business. We’re in a very active stage right now, trying to get a product into market within the next six to eight months. Q: How about working with your husband—what’s that been like? It’s been a wonderful thing to come in to work, talk about science on the way in, meet during the day and talk about science or department problems, go home and talk about science again [laughs], among other things, like sailing and family and other delights. It’s like a conversation that never stops. Q: Have you encountered much sexism in your career? Not a lot. I’m aware that it happens, but I really haven’t encountered a lot. Tufts has been remarkably free of it. We’ve had perhaps 50 percent of our division and faculty members who have been women throughout my time here. Q: You mentioned sailing as a hobby? We have done a lot of sailing, and we’re doing a lot more in our new boat. We’re looking forward to spending a lot of time doing that. We have a farmhouse on an island up in Maine, on Penobscot Bay. We love to sail up around Penobscot Bay and Down East—it’s just spectacular coastline. So there’s that, and continuing to build a company is fun. PHOTO: JOHN SOARES LOCAL HERO Delivera photos by karel navarro pando ⁄ getty images 8 tufts medicine winter 2007 nce Getting orphans and children living on the streets in Lima, Peru, to kick a soccer ball around was just the start by joseph donroe, a98, m.d. ⁄ m.p.h. ’07 as an undergraduate at tufts university, i held many jobs—from pizza delivery to construction worker, security monitor to event staff coordinator—but none was quite so influential as my work as a furniture mover, a job that I began my sophomore year. ■ Not your typical bunch of movers, the men and women at Gentle Giant Moving and Storage were an adventurous lot, many of them highly educated individuals who moved furniture to support their travels around the world. It was because of their stories of adventures in far-off places that, after finishing college, I, too, decided to take time to travel. I did what many of my Giant friends had done, move furniture, doing as much overtime as possible to quickly make enough money to throw on a backpack and shoestring around the world. When the money ran out, I would return to the United States and lug pianos and sofas around the greater Boston area until once again there were sufficient funds to get back out on the road. winter 2007 tufts medicine 9 m y trips were always a mixture of adventures and volunteer experiences, whether that meant building homes on a remote island in the Philippines, summiting Mount Kilimanjaro and then scuba diving with the hammerhead sharks off the coast of Tanzania, interpreting for medical teams in Ecuador or canoeing through the Brazilian Amazon. In early 2001, I found myself hitchhiking across the Chilean Patagonia, fly-fishing and mountain climbing along the way. When the season turned to winter, I quickly escaped north to Guatemala. There, I was immediately struck by the impressive backdrop of colors—the greens of the landscape, the rainbows of fabric woven and worn by the Quiche women, the bright yellows, oranges and reds of cement houses that line 10 t u f t s m e d i c i n e winter 2007 the streets, accentuated by explosions of bougainvillea. I was also struck by the number of children I saw working and living on the streets. Perhaps more than in any other place that I had traveled, the street children of Guatemala stood out. They were a constant presence, asking for food or money, and above all making you feel guilty as hell for not handing over your quetzals. One could not walk peacefully down the street or enjoy a coffee in an outdoor café without the constant hassling of begging children. Eventually you learn to ignore them. You can’t keep giving away your pocket change, and you soon get tired of feeling bad about your inability to really help. It is human nature to protect ourselves emotionally, and, like most constant things, one becomes accustomed to seeing the kids, and they soon become part of the normal background, much like the brightly colored houses and bougainvillea. As they become part of the normal landscape, they become less human, and it is much easier to tolerate their presence and feel OK about ourselves. So powerful was this reaction that it even happened to someone like me, who had entered medicine precisely to help such children. And so I passed my time in Guatemala, with a backdrop of colors and street children, the one seeming just as normal as the other, until an eight-year-old boy changed my view of the world. THE UNHAPPY MEAL On the morning of Good Friday, I awoke early and with camera in hand walked through the city. I wandered the unusually quiet, cobbled streets aimlessly, meandering between the brightly painted houses. Shops were closed. People were in their homes or in church. The normally bustling city was virtually empty. Without the pandering, shoe-shining and soliciting, my pueblo took on a whole new texture. I walked past a crying young boy in a tattered beige jacket, which contrasted starkly with the bright yellow wall that he sat against. His shoeshine box lay on the ground beside him, and he did not even look up to see if I needed my sneakers polished. I caught myself having walked several feet beyond him, surprised by my own indifference. At eight years old, he was crying, he told me, because he could not earn enough money to return home. He lived in a small village an hour and 40 cents away by bus, and he commuted here every day to shine shoes. At worst he would make enough money for his fare home and then back again the next day; at best he would also have money to eat. He lived with his 11-year-old brother somewhere on the streets of that far-off village, abandoned by a family who could not afford to raise them. On this Good Friday holiday, he had no business; there were no shoes to shine. He sat and silently wept because at eight years old, he Donroe plays with a child at the LimaKids Street Clinic. “A healthy childhood is something that all are entitled to,” he says. could not earn enough money to go home. I hoisted him up and together we walked toward a nearby McDonalds. I made jokes along the way to cheer him up, but he had a sadness and a seriousness that no child should know. We made it to the restaurant, and I offered to buy him anything on the menu he desired. He whispered, “Una cajita feliz.” I had no idea what he meant, but the woman at the register did and promptly prepared him a Happy Meal, complete with toy inside. The boy sat, opened his toy, and despite the fact that he had not eaten today, despite the fact that he had the outward maturity of someone forced to relinquish everything good about being a child, of someone who commuted two hours round trip a day to work in the city streets—despite all this, he unwrapped his toy, and it became at that moment the most important thing in his world. I fought back the tears and sat, silenced by what I had seen. In that instant, the street kids who had become such a normal part of the landscape suddenly became children. I saw the images of every child I had allowed myself to look beyond—how easily I had succumbed to viewing their plight as normal. How quickly I became so tolerant. I was brought back and taught such a lesson from an 8-year-old child. Their childhoods are stripped from them due to nothing more than the unfortunate circumstances in which they were born. They are forced to fend for themselves, to endure beatings, rape, hunger and abandonment. But given something as simple as a small plastic toy from a Happy Meal, a glimmer of what makes childhood good can be seen in their eyes, at least for a moment. LimaKids had its roots on that day as the search for solutions began. I learned that street kids were not as uncommon as they might seem from the vantage of Boston, Mass. They number in the millions, globally, including right here in the United States. They have been called the world’s forgotten children, and that they exist at all gives testament to the fact that they have been abandoned by both family and society. I bore witness to communities of children living on a garbage dump in Guatemala City, read the reports of street children in Brazil literally being exterminated by police and of countless human rights abuses to which the world seems to have turned a blind eye. Sickness and disease is common—much more common, not unexpectedly, than in their home-dwelling peers. Parasitic infections, sexually transmitted diseases, malnutrition, skin infections and psychological problems are the norm. This is a truly vulnerable population, yet direct access to health-care services is rarely available to them. winter 2007 t u f t s m e d i c i n e 11 SOCCER AS CURE Our mission became to create a program so exciting that children would choose to participate and one so passive that they would quickly forget that what they were involved in what was actually a health intervention. After having traveled through the developing world, it was clear that sports could provide such a medium—sports were the common thread between children of Dar es Salaam, Mindanao, Guayaquil and Quetzaltenango. Sports connected children living on the streets and children from poor, middle-class and wealthy families, literally leveling the social playing field. In Latin America, the love that children have for soccer could make this sport an ideal intervention medium. Sports had played an important role in my own development, having grown up playing multiple team sports and then later serving as captain of the Tufts basketball team. Aside from being a form of recreation in which all kids should at least have the option to participate, organized sports provide many other benefits. They can increase self-esteem and psychological well-being and can improve the symptoms of anxiety and depression commonly associated with childhood abuse. 12 t u f t s m e d i c i n e winter 2007 PARTNERS FOR CHANGE In the fall of 2001, I entered Tufts Medical School, but it was not very long before I found myself missing my work in those faroff places. Therefore, upon completing my first clinical year of school, I traded in my role as medical student for one of public health researcher. There was a position open to work with a non-governmental organization in Lima, Peru, and I quickly accepted the opportunity. Once again I found myself in the familiar position of working as a furniture mover to make enough money to sustain myself abroad before heading off. I did not go to Peru intending to work with street children, but when offered the chance to develop a project, the timing seemed right to try to implement the ideas that had been circulating in me since that day in Guatemala. By a fortunate turn of events, my mentor through it all became David Moore, a British physician and sports enthusiast working for the same research group. He had been touched in his own way by the children on the streets of Lima, and he, too, had been thinking of ways to make a difference. Together we began to plan the early elements of the intended intervention. Not long after, we met Rosario Arroyo, a Peruvian physical education teacher who already had years of experience working with the street children and orphans of Lima. The three of us worked to create the “PRISMA Championship,” a mental health intervention using soccer as our rehabilitation vehicle. We became partners, not knowing quite how far it all would go. Our program was designed to address both mental health and quality-of-life issues of orphaned children in Lima, the capital city. These children are a mixture of those who have spent time living on the streets and those who have not, but all have tragic histories of childhood victimization. Despite the number of different medical problems that these children enter into their orphanages with, we chose to focus on their mental health. BIGGER AND BETTER The original PRISMA Championship turned out to be a great success, with 13 orphanages and more than 150 boys and girls participating. We were able to show that when kids participated under the rules of the intervention, their self-esteem improved and, despite the very transient nature of our kids, we managed to attain a more-than-90-percent participation rate. The anecdotal evidence of the program’s success was even more telling. As one orphanage administrator commented, “These kids go through life looked upon as being different—they live in orphanages; many lived on the streets; they consumed drugs. The ability to participate allows them to feel like regular kids.” Since our beginnings in 2005, LimaKids to health care. The most important element Personally, I believe there was something has begun several projects in addition to the of the health clinic is our focus on transispecial about just giving kids a chance to play soccer league. We have increased our efforts tioning kids off the streets. The medical and be surrounded by positive and caring to improve quality of life within orphanages services that we offer set the stage for the role models. Whatever the case, we could not by financing and organizing recreational educational and social services provided to visit an orphanage afterward without hearactivities such as birthday parties, trips to the meet that end. While still very early in its ing kids cry out, “When can we play again?” movies and Christmas events. As a result, development, the LimaKids Street Clinic is This notion of givfast being recognized by ing our kids the children on the streets of to encompass more chance at a more norLima as a safe and caring mal childhood is what than sports and physical health. The organization place. drove us to continue LimaKids continues has provided birthday parties, trips to the movies to grow and positively our work. We since have grown, and the impact more and more and Christmas gifts as well. PRISMA Championchildren in Peru. I have ship has become the come to know many. I’ve LimaKids organization. Our championship some of these children have had their first listened to terrible stories of lost childhoods, has become a league, and the children opportunity to celebrate a birthday or receive and kids no more than half my size have involved now number more than 350. We a present on Christmas day. become some of my greatest teachers. One have developed a new set of rules whereby Our newest project is the LimaKids such child is Josue, a young boy with whom games are won or lost not simply by countStreet Clinic, designed to bring health servI became very close while in Peru, who was ing goals, but by playing in a fair and sportsices directly and free of charge to children placed in an orphanage due to the abuse and man-like manner. Some of our kids have living on the streets. Like the right to a neglect in his home. Last May, Josue invited even gone on to play with semi-professional happy childhood, a healthy childhood is me to visit his home and meet his mother. club teams, the scouts for which are consissomething that all are entitled to. In the Having spent every other Sunday with Josue, tently surprised by the level of skill and disclinic we see the most vulnerable of chilI looked forward to the chance to get to cipline displayed by our children. dren, children who otherwise have no access learn more about his family. LimaKids has grown winter 2007 t u f t s m e d i c i n e 13 WHAT HARD MEANS As I stepped down from the bus in one of the poorest districts of Lima, Josue excitedly met me and guided me through the dirt roads to his uncle’s house. In a small home, unkempt and with dirt floors and swarming flies, we ate lunch, and I noticed that Josue’s expression turned from excitement to shame. His three younger siblings still live at home, and from their physical appearances and interactions with their mother, it was apparent that abuse and neglect still continued. I listened to the mother’s own harrowing story of having grown up with abuse and extreme poverty and reflected on the terrible cycle that was being revealed. I escaped to the backyard to play with 14 t u f t s m e d i c i n e winter 2007 Josue and his younger siblings, and as I threw each child high in the air, the view up the side of the hill on which their home was located gave me pause. I saw shacks stacked upon other shacks, each additional level representing a deeper stratum of poverty, and children, dozens of children, dirty and with ragged clothes, working or playing in the few open areas along the hillside. This is the reality of tens of thousands of children in Peru. For me, there was a time when medicine actually seemed like a difficult path—the long hours, the countless tests, the huge financial commitment. Every other Sunday I was reminded, however, that hard is being 13 years old, facing a childhood within the confines of a poorly funded Third World orphanage, having witnessed your father sexually abuse your sister and having yourself been physically and emotionally abused. Hard is being 13 and feeling responsible for the care of your four younger siblings, of having dreams without the means to achieve them. Yet each Sunday Josue met me with a smile, and his strength assured me that there is no other path for me to take than that of medicine and service to these children. Josue and the children of Peru will always be a part of me. The work of LimaKids moves forward. Not unpredictably, as we have grown as an organization and the course of my own life pushes ahead, my role within LimaKids has changed. While I continue to direct its activities, I now do so from Boston rather than Lima. Instead of coaching soccer teams, taking groups of children to the beach and making visits to deliver medicines to kids on the street, my time is spent managing operations and advocating for voiceless children so that their reality may become exposed. There is still so much left to do. The author will graduate this spring. For more, see http://go.tufts.edu/donroe A TWO-PART FEATURE close encounters photo graphy by melody ko of the healing kind you are a seasoned physician. a new patient waits in your office. After you shake hands and say hello, how will you figure out what is wrong with this person and determine the best treatment? ■ Although the problem is the essence of the practice of medicine, the subtle detective work required by such an encounter is not something you were born knowing how to do. Instead, the relevant techniques had to be learned gradually, by close observation and through the example of your instructors. ■ In this special double feature, we look at how our medical school is teaching students to be more effective doctors, one patient at a time. The first story gives the perspective of a veteran instructor of the basic first-year course; the second examines the use of patientactors during third year to help students refine their skills. winter 2007 t u f t s m e d i c i n e 15 FIRST STEPS Livshin (center) leads her class. A veteran instructor in patient interviewing relates what she has learned by l isa y. l iv s hin, ed. d. i i am squeezed into a patient room at Tufts-New England Medical Center with my six students. We are on North 4, the general surgery unit. The student begins the interview with a nice openended-lesson-one-question: “Can you tell me what brings you to the hospital?” The patient, a 54-year-old woman lying in bed, responds by saying that four years ago, she was diagnosed with ovarian cancer, at which time she had surgery, radiation and chemotherapy. She was in remission for three years. The patient tells us she is back in the hospital because the cancer is back. My class appears tense. When she finishes speaking, my student pauses a moment. Then, straining for something to fill the void, he stam- 16 t u f t s m e d i c i n e winter 2007 mers, “Do you have any hobbies?” Welcome to the medical school’s “Patient Interviewing” course, a mandatory firstyear, first-semester class for all students. It is almost impossible to believe that I have been teaching this course for 20 years, but I began subbing as a doctoral psychology intern in child psychiatry in 1986. I was 25 years old and merely a hair older than most of my students. Psychologists in training do a lot of intakes—it is our rite of passage. Having worked in hospitals, clinics and mental health agencies for five years, I was an experienced patient interviewer. I had a knack for interviewing and enjoyed the challenge of learning as much as possible in the scarce amount of time allotted. Also, my personal history had its share of “bad-doctor experi- ences,” so I was eager to teach future doctors their lessons in treating patients with kindness and respect. The year after my internship, I became a full-fledged psychiatry staff member and signed on for another year of teaching the Patient Interviewing class. This is a course, simply put, on bedside manner. Students learn how to treat the patient as a person, not a disease. They learn about how an illness may impact a patient’s life—such as the patient with irritable bowel syndrome (IBS) who works on a construction site and has limited access to a near-by bathroom. Students learn that being an effective doctor necessitates knowledge of their patients’ home lives— for example, the elderly woman with rheumatoid arthritis who lives alone, has no support system and can no longer take care of herself. They learn how to talk to the patient like a doctor, which is not all that different from the way they would talk to a relative or friend. Most important, they learn how to ask questions that will lead them to an understanding of how the patient experiences his or her illness. STAYING WITH THE SILENCE The weekly class convenes at 1 p.m. on Thursdays for a lecture by the course leader, Dr. Jody Schindelheim, clinical professor of psychiatry. The lectures include guest speakers and exposure to new and difficult topics such as death and dying, domestic and substance abuse, and talking to patients about sex. From 2 to 4 p.m., the students accompany their instructors to classrooms in small groups of six. Not all instructors take their students onto the unit to interview a patient on the first day, but I always do. I always ask for a volunteer for the first interview and reassure the students that I will do the interview if they prefer. It is a fascinating exercise. The students immediately break all eye contact with me, and many begin searching the syllabus. Every few years a student offers to go first—one who usually has interviewing experience from working in a medical setting. Occasionally, someone volunteers who simply wants to get the interview out of the way and figures I can’t judge him or her too harshly on Day One. Ninety percent of the time, the class asks me to conduct the first interview. And so, on this particular day, I do. I begin interviewing a middle-aged woman who has been hospitalized for a minor procedure on her foot. As the interview proceeds, the woman strikes me as clinically depressed. I ask about her home life (lives alone) and her work (she hates it) and about what she does for enjoyment. Then there is silence. I stay with the silence. The class looks tense. I see them looking at me, willing me to speak. More silence. In a moment the patient is crying. The new medical students are noticeably uncomfortable with the tears, and several of them reach for tissues at the same time. I let her cry a bit and then say, “You’re sad.” Soon the patient is volunteering information about her depression. We talk about her extensive family history of mood disorders as well as her current symptoms. The class is in awe of what has transpired. Back in the classroom, we discuss the importance of learning to feel comfortable with a patient’s emotions and how doctors can communicate that ease. However, somehow the students walk away with the notion they need to make a patient cry in order to get a good grade. This is a rumor that has persisted throughout all my years at Tufts. A BADGE OF COURAGE My group interviews one or two patients per class. Every week I designate one primary interviewer and one back-up interviewer per patient. The back-up person takes over when her classmate hits a wall and runs out of questions. I assure my students that I am there to rescue them should they get into a difficult spot. I usually wrap up each interview by asking questions that have been missed entirely or pursuing areas that have not been fully explored. Sometimes I model how to talk to family members who may be in the room. Often I am using this end-of-class time to demonstrate how to ask a question about the two toughies: sex and death. At these moments I am reminded of the students’ relatively young ages and mixed cultural backgrounds. Many grew up in homes where it was considered rude to ask intimate questions. Or they came from cultures where it is inappropriate to make personal inquiries of an elderly person or someone of the opposite gender. Simply asking a patient’s age can be difficult for some students. But my students sell themselves short. Although they have been in medical school for only a short while, their white coats and their presence on the unit legitimize them in the eyes of the patient. I think about all the patients who had no modesty with the class—the ones who didn’t care about which body parts were exposed as they lifted their gowns to show an incision or bruise. For many patients, that incision is a badge of courage to be shown with pride. Or its display can be an attempt to work through the trauma of having been cut open—of bodily intrusion. Students often encounter more graphic detail than they expected. Three of my students have fainted over the years, and two have vomited, all claiming to be overcome by the heat in the patient’s room. Not all patients are willing to be interviewed. Many of them have had enough of the teaching hospital environment and its endless stream of students and interns. However, my experience has been that most patients do agree to be interviewed. They want to help teach. They have a story to tell about their illnesses, and frankly, they are eager to break the monotony of their long days with our visit. Often, it is the patient who primarily teaches the students. One patient in her 30s had a wheelchair by her bed. The student interviewer astutely picked up on this (students are taught to observe the patient’s personal belongings to glean information) and asked, “How long have you been in a wheelchair?” The patient gently corrected the interviewer’s question and told us that she had “used the chair for six years.” She made sure we understood the distinction between being in a chair—the dependency that this implied—and using a chair as an aid. Another instructive case concerned an 86-year-old man lying in bed in a silk robe and monogrammed slippers; he had a Wall Street Journal, briefcase and laptop by his winter 2007 t u f t s m e d i c i n e 17 DEEPER IN bed. The student began an excellent interview, learning a great deal about the course of the man’s heart condition. Then, missing all the clues, she asked, “How long have you been retired?” to which the patient replied that he still headed up a large law firm. WHEN TO BE QUIET The lessons I impart to my students haven’t changed over the past 20 years. First, listen and make no assumptions. One day you may be treating your 227th heart attack, but it’s usually the patient’s first. Be compassionate. Patients are vulnerable—lying in bed without the dignity of their clothes, feeling sick and uncertain about their health, stripped of the appearance they usually make when meeting someone new. There are many factors that influence how a patient experiences illness—ask questions to find out. Don’t be afraid to ask about age, sex and death. If the patient is 50 and looks 70, that’s important information. If the patient is practicing unsafe sex, you need to know. The scariest part of being sick is getting a little closer to the possibility of death. You can help make all of it less frightening for the patient to talk about simply by being comfortable asking. Then keep listening. My favorite moments over the years have been when I see students “get it.” At these times, they are totally present during their interviews. Their eyes aren’t looking off in search of the next question. They are listening and responding to what the patient has said. They’re not thinking about me or their peers standing behind them. They know when to be quiet, wait a beat, and let the patient show the way; they also know when to steer. They let the patients know they are listening by paraphrasing what has been said and asking the next question that begs to be asked. The interviews flow, the patients open up, and we learn what we need to know. The author is an instructor in psychiatry at the medical school. 18 t u f t s m e d i c i n e winter 2007 Patient-actor Kia Scott plays her role for Candace Barnes, ’07. Patient-actors teach students how to fine-tune their skills m mr. mchale, a 55-year-old construction foreman, sits fully clothed on crinkly white tissue paper covering the exam table, waiting for the doctor. He’s there to go over the results of a recent blood test. At five feet, six inches tall and 195 pounds, he’s a little overweight. He has high cholesterol, and his tennis partner just died of a heart attack. Mr. McHale is nervous. Mr. McHale is also fictional. A “standardized patient,” the McHale character by jacqueline mitchell helps train third-year students to take medical histories, make diagnoses, deliver bad news, give advice and, most important, hone their bedside manner. (For an introduction to the “Patient Interviewing” course required of first-year students, see “First steps,” page 16.) A means of teaching and assessing clinical care, standardized patient exercises are becoming increasingly important tools in medical education, and now extend through all departments at the medical school. Part of the family medicine clerkship, the McHale exercise is known as a “nutritional intervention.” Because McHale’s medical and personal history put him at increased risk for cardiovascular disease, the students in training will have to counsel and moti- M EE T A PAT I E N T - A C T O R KA RE N FORA N DE MP SE Y Growing up west of Boston, Karen Foran Dempsey always dreamed of getting married and having babies. But some doubted Karen, diagnosed with juvenile rheumatoid arthritis (RA) at just two-and-a-half years old, would ever realize her dream of giving birth. Among the doubters: an OB/GYN who declined to give her a routine exam, not wanting to put her through “any more suffering,” Dempsey recalls. But Dempsey, 39, never let others’ ignorance get her down. She gave birth to twin boys, Joseph Edward and William Edward on September 11th, 2006, their parents’ second wedding anniversary. The boys are named after both of their grandfathers. Karen met her husband Mark, who has psoriatic arthritis, in 1999 when they both worked for the MetroWest Center for Independent Living in Framingham. Karen has been an advocate, peer counselor and consultant for various organizations for the disabled—including the MetroWest Center—since she graduated from Regis College. Mark works as a compliance officer for the State Department of Public Safety. People often ask the new parents, who live with Karen’s mom, a beagle and a cat, if the babies will inherit arthritis. Karen and Mark, who are volunteers with the Arthritis Foundation, looked into it. “Their chances [of having JRA] do not increase,” she says. “But if they do, what’s the tragedy? Who better than us to deal with it? We’ll deal with whatever we’re given.” vate the patient to make potentially life-saving changes to his diet and exercise habits. Doing so will require a suite of abilities that are hard to test on traditional exams: attention to detail, communication skills, empathy, problem-solving and even a dash of motivational speaking. DON’T BE AFRAID Yaffa Vitberg, a third-year medical student whose warmth and energy fill up the sterile space, enters the room and introduces herself to McHale, a patient she’s not seen before. Played today by veteran patientactor Jim Summers, the McHale character is a method actor’s dream role. His medical history and social back story have been painstakingly fleshed out; his wife does the shopping and cooking; his job requires him to be on his feet most of the day, and he has weakness for jelly donuts. (No wonder his glucose level is slightly elevated.) Registering her patient’s anxiety, Vitberg asks McHale to sit in one of the chairs so they can go over the print-outs together. As the two review McHale’s LDL and HDL cholesterol levels, glucose and blood pressure, the man’s face darkens. “How bad is it?” he asks Vitberg, a 24-year-old from Setauket, N.Y. “Your risk is elevated,” she says, then changes tack. “I’m going to help you with this. We can work together as a team.” After Vitberg asks McHale to detail the foods he eats and the physical activity he gets on a typical day, she explains the difference between healthy fats and trans- and saturated fats and cautions him to avoid the latter. She also prescribes 30 minutes of exercise “most days of the week.” And with that, the 14-minute exam is over. “I needed more time,” she says immediately. “I wasn’t even able to get into smoking and drinking.” But Summers, a trained patient-actor taught to evaluate the med students’ examination skills, is impressed by her performance, as are two other observers, Amy Lee, ’02, clinical instructor in public health and family medicine, and another third-year student. All three praise her organization, her upbeat attitude and her ability to establish rapport with her patient. “You were an enthusiastic cheerleader,” says Lee.“But when he started asking about his risk, don’t be afraid to tell him you’re concerned.” “Get feedback from the patient,” Summers suggests. “Have him tell you what he plans to do. Have him write it down. Because that’s where the rubber meets the road.” The students take the patient-actors’ advice very seriously. “Their desire to be good doctors is so apparent, their willingness to hear specifically how to improve,” says Ylisabyth (Libby) S. Bradshaw, D.O., M.S., assistant professor of public health and family medicine, who oversees some of her department’s standardized patient exercises. “It’s humbling when you see somebody so receptive.” Young doctors’ clinical skills are traditionally assessed by attending physicians as students go through rotations treating real patients. That assessment, however, can be hit-or-miss, because the interns and attending physicians might interact only sporadically. The standardized patient exercises offer a much more in-depth and reliable form of evaluation early on in a young doctor’s career. “Teaching even a small group, you don’t winter 2007 t u f t s m e d i c i n e 19 DEEPER IN ME E T A PATI E NT- A CT O R PAU L KA H N Like any journalist, Paul Kahn’s beat sometimes takes him in unexpected directions. A contributor to New Mobility magazine, a monthly publication for wheelchair users, Kahn at first took only a professional interest in the standardized patient exercises he observed at Tufts. But after watching the students, “bright and young enough not to think they know everything,” make striking progress in just one afternoon, Kahn volunteered to be a patient-actor. Kahn has centronuclear myopathy, a congenital neuromuscular disability, and uses a wheelchair. A full-time writer and playwright, he lives with his wife Ruth and their cat Cairo. Kahn edits two newsletters, including “Opening Stages,” a quarterly newsletter for people with disabilities pursuing careers in the performing arts. His own plays have been staged in Massachusetts, Rhode Island, Maine and Connecticut. As a patient-actor, he uses his writer’s talent for observation to note what the students do right and do wrong in their interactions with him. really know how much the [individual] student is getting,” Lee notes. “And there are just some intangible things you want every doctor coming out of Tufts to be good at. Whether they become clinicians or not, they should come across as kind, be able to talk easily with patients and explain things in understandable ways.” SPES HERE TO STAY Using standardized patients in medical education is not new. Howard S. Barrows, a neurologist and professor at the University of Southern California, pioneered the use of patient-actors to train his third-year clerks in the 1960s. Recognizing that the fairest way to evaluate his students was to watch them handle the exact same case, Barrows based the character of “Patty Dugger,” a paraplegic woman with MS, on one of his actual patients. The method was met with resistance from the medical establishment, but as problem-based learning gained currency in medical education, so did the use of standardized patients. In 2004, the U.S. Medical Licensing Examination (USMLE)—the test all medical students must take to practice in this country—instituted a standardized patient exercise to evaluate students’ clinical skills. “Standardized patient exercises are here to stay,” according to Mary Lee, university associate provost and dean for educational affairs 20 t u f t s m e d i c i n e winter 2007 at the medical school. “The clinical setting has become so fast-paced that students must enter with higher skill levels. The standardized patients are an excellent means to teach better communication skills and cultural competency.” To ensure Tufts medical students attained those skills, Margo Woods, D.Sc., associate professor in the nutrition/infection unit in the Department of Public Health and Family Medicine, developed the McHale exercise in 2001. In the fall of 2002, Bradshaw launched a standardized patient exercise with disabled patients based on the same model. A QUIET, CARING MANNER Shortly after Vitberg leaves the exam room, her classmate, Shreya Raj, conducts a “followup” with Mr. McHale. Six weeks supposedly have elapsed, and McHale’s new blood work results show he’s been diligent with his diet. His bad cholesterol is down, but his new low-fat menu leaves him hungry, and his triglycerides are up—a clue to Raj that his diet is now too high in simple carbohydrates. What’s more, his wife’s new job leaves him to fend for himself for dinner, and he has been subsisting on low-calorie frozen entrees that he doesn’t enjoy and don’t fill him up. McHale is frustrated with the diet, and he’s still nervous about his risk for heart attack. Raj delves deeply into his new diet and suggests he can make a low-fat diet more satisfying by increasing his protein and fiber intake. You’d want Raj to be your doctor. Her interview is organized; her quiet manner inspires confidence, and she’s caring and empathic—maybe too much so. “Don’t absorb the patient’s anxiety. You can be empathetic without being sympathetic,” Summers cautions her. “Don’t forget to smile.” RARE CASES By the time the med students complete their third year, they’ve already seen their share of real patients. But the SPEs can give them valuable experience with patient populations they might see only rarely in a real clinic. Today, third-year medical student Kate Forssell is ready to see a standardized patient named “Chris Walker.” Forssell knows she’ll be problem-solving the patient’s sore shoulder. She does not know her patient will have a disability. “Anyone could have shoulder pain, but it could have more importance to someone who already has limited mobility,” says Linda Long-Bellil, who worked with Bradshaw, Dr. Wayne Altman and Paula Minihan—all of the Department of Public Health and Family Medicine—to develop the Chris Walker case. Having dealt with juvenile rheumatoid arthritis since she was just two years old, Karen Dempsy, the “patient,” uses a motorized scooter to get around and has limited use of her hands. She has seen her share of doctors, and she’s passionate about teaching the next generation of doctors how to treat people with disabilities. “A person with disabilities has complexities that need to be addressed by doctors,” says Dempsey, who’s been involved with patient-acting for the last four years. “So it’s okay to ask questions, but don’t over-emphasize the disability. You have to see the whole package.” Today Dempsey, in the role of Chris Walker, tells Forssell her shoulder has hurt her for two or three weeks and is getting worse. Walker goes on to say that she’s leaving her old doctor who “seemed uncomfortable with my disability.” Forssell uses the moment as a chance to explore Walker’s disability. With her series of questions, Forssell reveals that the patient works as a data entry clerk, which often requires her to heft heavy file boxes on and off shelves she can’t quite reach from her chair. Correctly diagnosing the patient with tendonitis, Forssell advises Walker to lay off the heavy lifting and offers to write Walker’s boss a note. She prescribes ibuprofen, applying ice and heat to the shoulder and a round of physical therapy. “I’d like to see you back in two weeks, unless the pain suddenly worsens,” she concludes. Like her peers, Forssell impresses her patient-actor and her faculty observer, Libby Bradshaw. They applaud her diagnosis, her organization and her transitions from topic to topic. But while Forssell established a good rapport with her patient, Dempsy points out some questions a doctor might not think to ask a disabled person. “You might touch a little more on social history,” Dempsy suggests. “Does somebody help you? Do you have transportation to the physical therapist?” As with the McHale case, the patient-actor advises, “You have to know what the patient will do when she gets home.” Jacqueline Mitchell is a senior health sciences writer in Tufts’ Office of Publications. M E E T A PAT I E N T - A C T O R L ILLI A N JOHNS ON Devang Dave, ’07, and Adam Weston, ’07, meet with patientactor Betsy Laitinen. Lillian Johnson is concerned about hybrid cars. It’s not that she’s opposed to conservation, it’s just that Johnson—blind since birth—can’t hear the hybrids’ quiet motors when she’s poised to cross a street. Luckily, she has Keesha, her seeingeye dog, to keep her out of harm’s way. “The dogs are taught not to go if it’s not safe. Words can’t begin to express the independence she’s given me,” says Johnson, who lives with her sister in the Arlington home her grandfather bought in 1948. A graduate of the Perkins School for the Blind, Johnson loved participating in track and softball and dreamed of being a Phys. Ed. teacher one day. Johnson never lost her love for physical fitness. Among her many volunteer efforts, Johnson is an active member of Ski for Light, an international non-profit that pairs sighted and blind cross-country skiers. In 1995, Johnson was chosen to represent the United States in a 22K race in Norway, where the program originated. “I felt so exhilarated, I just wanted to do it again,” said Johnson. A standardized patient-actor with Tufts for four years, Johnson is the only blind role-player and the only one with a guide dog. “It’s a wonderful experience for me and I look forward to these sessions every time,” says Johnson. “At the end of the day, I hope I made a difference.” winter 2007 t u f t s m e d i c i n e 21 by bruce morgan I illustrations by ken orvidas The GOOD Worms A gastroenterologist at Tufts argues that intestinal parasites may be essential to a healthy immune system parasitic intestinal worms and human beings have a relationship that goes way back. The two have been inseparable since Adam and Eve strolled through the Garden of Eden. Calcified worm eggs have been found in the internal organs of mummies dating from 1200 B.C., and Egyptian medicine contains descriptions of what are almost certainly parasitic infections long before that. Worms love dirt and thrive in dirty places. Lucky for the worms, human beings have generally been a messy lot. As Dr. Joel Weinstock, professor of gastroenterology and immunology and chief of the Division of Gastroenterology at Tufts-New England Medical Center, puts it succinctly, “Most people have lived in filth.” 22 t u f t s m e d i c i n e winter 2007 F or a homegrown example, he asks us to consider an American boy living in a small Midwestern town on a summer morning in 1872. The boy runs outside to play in the street. There are horse droppings and raw sewage there. He cuts through a field barefoot to reach a friend’s house. Worms lie in wait along the earthen path. He races home for lunch. His sandwich and water, unscreened by any health agency or government office, are likely rife with parasites. Often on a microscopic scale, parasitic worms (or helminths) wriggle into their hosts directly through exposed skin or by being ingested in food and drink. There are about 90 relatively common species of helminths, many of which live in harmony with their hosts. “Most worms have minimal negative effects, but there are a few really bad actors,” Weinstock notes. The nasty batch includes tapeworms, which inhabit the human gut and may reach up to 35 feet in length; ecchinococcus and schistomosa, which can cause significant liver disease in their hosts; and onchocerca, known for blinding people in Africa and parts of South America, where the worms are transmitted by sand flies. Worms have lost some ground lately. Starting in the 20th century, it has been taken as a general rule among public health officials in industrialized nations that eradicating the parasites through better hygiene is a smart move. Worms have suffered from bad press forever, and you can understand why. They creep people out, and every so often, they make people retching sick. But, according to Weinstock, the prevailing bias against worms was never really based on hard evidence. It was more of a cultural habit of revulsion carried on unthinkingly. He snatches a textbook off a shelf and shows a densely printed chapter in a current medical textbook that discusses intestinal worms in entirely negative terms. “There,” he says. “Look at that,” indicating the three or four brief citations at chapter’s end. “There’s not much data behind those assertions.” Not that it ever mattered much to 24 t u f t s m e d i c i n e winter 2007 public health activists. “The consensus has been, ‘these things are awful—we’ve got to get rid of them,’ ” says Weinstock, who grew up in Michigan and retains a certain Midwestern openness, a willingness to be surprised, on his features. And so, with the best of intentions, we as a society have roared down that antiseptic path. Beginning with immense public works projects that encircled American cities around 1900, but even more emphatically since the hygiene craze of the 1950s, when household germs in suburban kitchens were viewed as a threat akin to communism, our water has been filtered, our food purified and our sanitation improved dramatically. The operating room of modern life has been scrubbed clean. Many infectious diseases have been drastically reduced or altogether wiped out along the way. That’s the good news. But in a hypothesis that is at once counter-intuitive and queasily unexpected, Weinstock argues that we may have gone too far with our clean-up efforts. In the process of ridding ourselves of stubbornly resistant, even deadly pathogens, he says, we have also eliminated a batch of naturally occurring agents that play a vital role in regulating the health of our immune systems. “We’re not saying all worms are good, but the bad side might be overemphasized, especially for some worms,” offers Dr. David Elliott, Ph.D., a former colleague of Weinstock’s at the University of Iowa who has co-authored a number of articles with him on the science of immune regulation by intestinal worms. “We seem to have thrown the baby out with the bathwater.” LACK OF EXPOSURE The background here is ominous. For whatever reason, something is clearly out of whack with immune response among residents of industrialized nations around the world. Rates of occurrence for asthma, Type I diabetes, multiple sclerosis and inflammatory bowel disease (or IBD, which comes in condition remains practically nonexistent in underdeveloped countries with poor sanitary conditions. A common presumption on the part of observers has been that the cause for the rise in autoimmune diseases is environmental, linked to chemical exposure of some kind, perhaps, or more dust in the air, or the greater use of vaccines in places like the U.S. Weinstock needed some hard numbers to buttress or refute his working hypothesis that people and worms historically have enjoyed what he calls, without the least hint of irony, a “good parasitic relationship.” To gather evidence, he pored through public health data gathered across the American South in the 1930s that showed that as many as 70 percent of the residents carried Weinstock’s pivotal question took the scientific inquiry in a whole new direction. The mental leap involved had the effect of rendering a negative print of a familiar scene, whereby black goes white and white black, reversing the figure and ground. two principal forms, Crohn’s disease and ulcerative colitis)—the Big Four diseases that involve a malfunctioning immune system—have risen sharply in industrialized nations over the past half-century. “They’ve gone up like this,” says Weinstock, flicking a thumb toward the ceiling, while remaining rare in the developing world. The proof of the disparity is everywhere. Each year, for example, about 600,000 Americans are diagnosed with IBD. “It turns out that countries where IBD is common are those industrialized, developed nations like the United States, where there are no intestinal helminths,” confirms Dr. Robert Summers, director of clinical programs for the gastroenterology division at the University of Iowa, and like Elliott, a frequent past collaborator with Weinstock. “Conversely, where helminths are prevalent, the incidence of IBD is very low.” Asthma supplies another intriguing case study. The incidence of asthma among children living in the United Kingdom has gone from less than 5 percent in 1964 to more than 25 percent in 2001. By late 2004, asthma was touching one in five households in the U.K.—one of the highest rates for the disease of any country in the world—and killing a British citizen, on average, every seven hours. Meanwhile, the and the U.K. that are solidly built up and civilized. In a moment of inspiration that resembled a comic book lightning flash, Weinstock turned this idea on its head. Back in the early 1990s, he happened to be working on two book projects at the same time. One book concerned parasitic worms, and the other addressed inflammatory bowel disease. Weinstock noticed that the first had declined in number as the other rose. “Deworming and the rise in IBD are inversely related,” he said. In contrast to what practically everyone in the world believed, the missing worms seemed to be having a deleterious effect on human health. “What if,” he asked recently as he sought to replay his thinking from 10 or 15 years ago, “the increase we see in autoimmune disease is due to a lack of exposure? What if it’s caused by something that we’re no longer exposed to that we should be exposed to? Let’s start from scratch. Can something affect the immune system because you’re not exposed to it?” Weinstock’s question took the scientific inquiry in a whole new direction. The mental leap involved had the effect of rendering a negative print of a familiar scene, whereby black goes white and white black, reversing the figure and ground. worms without any ill effect. During this period, only about 400 people had died from parasitic infections—mostly from trichninosis—out of a rural population of millions. “That’s a pretty small number, given the sample size,” Weinstock points out. “So just how dangerous were these worms?” A LID ON INFLAMMATION Consider the lowly parasite. This is a minicreature—could be a flea, a tick or a nematode—that attaches itself to a host and relies on that host for survival. Although in general parlance we put the parasite in a lower box than the host, and shift our tone of voice to something derogatory whenever we utter the word, nature doesn’t really work that way. The relationship between the two is symbiotic. As Weinstock explains, “The first law of parasitology says that the parasite must impart a survival advantage to the host.” And this makes perfect sense, because evolution has nothing judgmental about it. Any worm that gets into the body faces a huge, immediate problem. How can the intruder survive when the body’s immune system is poised to destroy it? One tactic is to hide. “Through co-evolution,” Weinstock suggests, “the worm has learned our immune system better than we know, and it winter 2007 t u f t s m e d i c i n e 25 modulates our immune system to make itself essentially invisible.” The hypothesis is that this modulation stems from a cellular network of “regulatory pathways” that the worm triggers within the host. In effect, the pathways put a lid on the immune system’s tendency to flare up over infection, holding the response in check. “We’re better off having these pathways,” Weinstock says. “Everything has to be kept in balance with the immune system or it will destroy you.” David Elliott, his colleague back in Iowa, concurs. Turning to electricity for his analogy, Elliott describes the role of worms in the host’s body as supplying “safety circuits that prevent the immune system It’s not all theoretical. In Brazil recently, doctors noticed that a group of children began suffering from asthma once they had been removed from their parasite-rich bioenvironment and purged of worms. When the children returned home and were once more exposed to the processes of their fecund natural milieu, the asthma went away. Many gastroenterologists have followed Weinstock’s work with keen interest. Dr. J. Thomas Lamont, for one, sounds willing to be persuaded. “I think it’s a very original and unique idea he has,” says Lamont, chief of gastroenterology at Beth Israel Deaconess Medical Center in Boston and an associate muttering, “You want to do what with these worms?”—but eventually the agency said yes, and the studies in Iowa began. In 1999, six patients with either Crohn’s disease or ulcerative colitis who had not responded to conventional treatment volunteered to participate in an experiment at the Iowa lab. They were asked to swallow capsules containing a low dose of microscopic whipworm eggs suspended in liquid. The helminth used in the study was carefully chosen for its benign characteristics: It could not penetrate the skin or multiply within the body, and had the capacity to colonize for several weeks at most. The hatched eggs were shed harmlessly in the stool. Scientists have determined that parasitic worms can suppress allergy by inducing a class of immune cells known as regulatory T cells, which interact with inflammatory cells by sending them “off ” signals. from going haywire.” There’s your host’s survival advantage right there, in the implications of that last, loaded word. By being intimately involved with each other, both the parasite and the host have improved their odds of living to see another day. It’s a classic win-win.“The parasite downregulates the immune system for its own benefit,” explains Rick Maizels, an immunologist at the University of Edinburgh in Scotland who is familiar with Weinstock’s work. “But doing so has wider ramifications, because it also dampens unrelated immune responses such as allergic responses.” Scientists have determined that parasitic worms can suppress allergy by inducing a class of immune cells known as regulatory T cells, which interact with inflammatory cells by sending them “off” signals. “These regulatory T cells may exist naturally to prevent us from suffering autoimmune disease,” Maizels told a British reporter recently. “We think the mechanism that is protecting us from our immune system is also protecting the parasite from our immune system.” 26 t u f t s m e d i c i n e winter 2007 editor of The New England Journal of Medicine. “If this idea has legs, it’s going to be a breakthrough.” SOME WHIPWORM EGGS Who would have figured a town in pastoral eastern Iowa to be the locus for people burrowing into the niceties of the human immune system? But that’s the way things panned out because that’s where our guy happened to be, and he soon got those around him excited about his pet notion. “We were first to the gate,” says Weinstock bluntly, referring to his University of Iowa colleagues. “No one else was ready for this.” Roughly 10 years ago, the Iowa team (Weinstock, Summers and Elliott, among others) began with animal studies, initially conducting experiments using mice and pigs. These studies generally confirmed their working hypothesis. The logical next step was human studies, which required approaching the FDA and winning the agency’s approval through normal channels. One can only imagine some poor FDA administrator sitting at his or her desk and Researchers found that the Crohn’s disease got better in all six patients. For five patients, the disease went into remission for up to five months, while in the sixth, the condition “improved substantially but did not obtain clinical remission,” according to Weinstock. The patients experienced no negative side effects from ingesting the worm eggs, and after about three weeks, when the patients gradually relapsed, their symptoms did not appear to be any worse than before the experiment. More recently, the University of Iowa team asked a group of 29 Crohn’s patients to swallow whipworm eggs every three weeks for six months. Once again, these were patients for whom standard treatments had failed. Results were just as impressive as before. By the end of the study, all but one of the patients had shown improvement, with 21 reporting no symptoms at all. The results were published in Gut in 2004. For anyone who can’t imagine anything more repulsive than popping a vial of whipworm eggs into your mouth, bear in mind that these are patients under duress. Common symptoms of Crohn’s include abdominal pain, bloating, fever, persistent diarrhea, rectal bleeding and weight loss, among other torments. “It was almost never a problem” convincing patients to swallow the worm egg capsules because of how desperate they were for relief, Summers relates. “They would say, ‘Well, if it has a chance, I’ll do it.’ ” A double-blind study published in Nature Clinical Practice Gastroenterology & Hepatology in 2005 further confirmed the merit of the Iowa team’s approach. In this study, which involved 60 patients suffering from ulcerative colitis, those treated with whipworm eggs fared demonstrably better than those who took placebos. Summers, who believes that Weinstock’s hypothesis “may have important implications for other autoimmune diseases not related to gastroenterology,” is more convinced than ever of the gold that lies inside the mountain. Over the past decade, he has seen more than 100 Iowa patients treated effectively with helminth eggs without side effects of any kind. Asked if he knows of any refutation of the team’s hypothesis from experiments done anywhere, he answers simply: “Not really.” NOT DONE YET The world is waking up to the news. Maizels, the Scottish immunologist, has been a true believer since he came across Weinstock’s papers on the topic of helminths and immune regulation a number of years ago. Maizels calls Weinstock, whom he has invited to speak at the University of Edinburgh, “a leading force” in the emerging field. The two men joined to organize the first international conference on the topic last year, attracting 150 scientists to Germany, where the groundswell of excitement was palpable, according to Maizels. Could worms have a healing effect comparable to what they have already demonstrated in the treatment of Crohn’s disease and ulcerative colitis on other autoimmune disorders such as asthma, Type I diabetes and multiple sclerosis? For now, that’s only one of many questions looming over the field. Gastroenterological treatments based on Weinstock’s research are currently in development. In an expansive moment in his office, Weinstock suggests that worm therapy stands a chance to reduce the prevalence of autoimmune disease in Western societies by as much as 90 percent. “We’ve done a lot of work over the past 10 years, and we’re not done. It’s not time to open the champagne yet,” he cautions, “but I don’t think we’re wrong. It’s not too early to say, ‘Yeah, these puppies have an effect, and they could play a role in the treatment of disease.’ ” Elliott, his Iowa colleague, rings the victory bell more forcefully, like someone calling the world’s doctors and scientists to dinner from the farmhouse porch. “You’ve got all these diseases of developed countries, all these illnesses of development. Why?” he asks rhetorically. “Ours is the strongest explanation. It’s the helminths, guys.” Bruce Morgan is editor of this magazine. winter 2007 t u f t s m e d i c i n e 27 A former dean of the medical school describes growing up on the King Dean Cavazos in 2006 28 t u f t s m e d i c i n e winter 2007 Ranch in Texas as the foundation for his accomplishments in later life at a ceremony in the last room of the white house, on september 20, 1988, Vice President George H.W. Bush swore me in as U.S. secretary of education. I was the first Hispanic appointed to the Cabinet in the history of the United States. A few weeks before, President Ronald Reagan had asked me to join his Cabinet, and I was unanimously confirmed by the U.S. Senate. My wife, Peggy, and I were very pleased that our 10 children, most of their spouses and one grandson—none of whom had visited the White House before—could be there. Their presence made the ceremony a family affair. Richard Mifflin Kleberg Jr. in the foreground and Lauro Cavazos Sr. to the rear. Roping on Anita Chica, King Ranch, 1960. by l auro f. cava zos , ph. d. JOHN A. CYPHER/MAIN PHOTO; MELODY KO/CAVAZOS PORTRAIT winter 2007 t u f t s m e d i c i n e 29 President Reagan looked on while Vice President Bush read the oath of office. Peggy held our family Bible, on which I rested my left hand while I raised my right one to repeat the oath. I felt great pride, not because of any personal accomplishment or achievement, but because this event marked a new beginning for Hispanics in our nation. During the swearing-in ceremony I remembered my parents. They would have been so proud to see their son at the White House on a beautiful day in September. I remember thinking how my parents spoke Spanish to each other and how I had started my education in a two-room schoolhouse. I tried to recall what events, circumstances and good fortune had shaped my life in such a way as to result in my appointment as secretary of education. I decided that the many excellent lessons I learned while growing up on the King Ranch in Texas had played a big part. It was on the ranch where I was taught the value of hard work, the importance of learning, the significance of commitment and dedication to worthy causes, how to make decisions and the great value of family. Honesty, loyalty, integrity and love of country were instilled in me. In other words, on the King Ranch I learned how to live. During my childhood years it was mostly my parents who fashioned my life, but the men and women working and living on the ranch were also my teachers. So my journey to the White House began on a ranch in Texas. A CARING PLACE I was born on January 4, 1927, on the 825,000-acre King Ranch in South Texas. The ranch is about the size of the state of Rhode Island, and at one time it comprised approximately 1,250,000 acres. The King Ranch has always been home to me, even though I have been away from it for many years. Just the thought of the King Ranch stirs grand memories in my mind. When I think about growing up there, I recall my childhood days, my parents, brothers and sister, relatives and many of the fine people who worked on the ranch. It was a remarkable place, so it is not surprising that the les- More than a million acres at its peak, the King Ranch is today about the size of Rhode Island and remains legendary. “People were born on it, worked there all their lives and died on it,” says the author. “It was a remarkable place.” sons I learned there about life are still deeply ingrained in me. In the late 1920s, ’30s and ’40s, my childhood years, the King Ranch was fertile ground for the growth and development of children. Parents and those who lived on the ranch stressed education. The Great Depression had slowed the nation’s economy to a crawl. Money was short everywhere, and across the nation people were out of work. But on the ranch, in the face of these economic difficulties, the emphasis was on people. It was a caring place. In those days, people who worked for the King Ranch and did their jobs well had work for life. They could expect the King Ranch to educate their children and provide health care, housing, money and food for the entire family. They knew that when they died, the ranch would bury them. One worked long hours helping to improve the ranch. People were born on it, worked there all their lives and died on it. Their children followed in their footsteps, and some families on the ranch, including mine, had been there for several generations. They were Kineños, King’s People. I am a fourth-generation Kineño. Running the ranch were members of the Kleberg family, the driving forces who eventually developed it into the greatest cattle ranch in the world. They instilled the tradition of caring and looking after those who worked there. This tradition of caring was in the spirit and commitment of the founder of the ranch, Capt. Richard King. As a child, I remember seeing the Klebergs working side-by-side with the men on the ranch. All the Klebergs were fluent in Spanish, had superior equestrian skills and knew the cattle business. They cared so much about the people working there that to them the ranch was a family with many skills and talents. Some stayed on the ranch to help enhance its excellence in cattle and horses. Others left but carried with them the values and the teachings of the Kineños. No other ranch in this nation has produced a four-star general and a Cabinet secretary— my brother Richard and me, respectively. TWO LANGUAGES AT HOME My father was Lauro F. Cavazos and my mother, Tomasa Alvarez Quintanilla. Like my sister, Sarita, and my brothers, Richard, Robert and Joseph, I was born at home on the King Ranch. No one back then saw any reason for Mother to go to a hospital; she 30 t u f t s m e d i c i n e winter 2007 ILLUSTRATIONS: CYCLONE DESIGN, INC. uring my childhood years it was mostly my parents who fashioned my life, but the men and women working and living on the ranch were also my teachers. was not sick, just giving birth to a child. The local country doctor attended her. My maternal grandmother (Mama Grande Rita) and aunts helped out. They lived in the barrio in Kingsville, three miles away, and as was the custom, they came to the ranch to help Mother and Dad on the day I was born. On the Santa Gertrudis Division of the King Ranch, Dad’s work was typical for young cowboys: riding fences, breaking horses and herding and working cattle. In 1913, Caesar Kleberg, the foreman of the Norias Division of the ranch, had Dad transferred from the Santa Gertrudis to the Norias Division. There, he worked as a member of the corrida, or cow camp. Dad brought his many skills as a cowman to Norias. Many believed that when Dad rode a horse, he and it were as one. Dad and Robert J. Kleberg, the manager of the ranch, were considered two of the best horsemen in Texas. My parents were remarkable people. They had great love for their children and worked to ensure that we would be nurtured and educated. They taught us ethics and values, not from a book, but by their example of day-to-day living. Their formal education was limited. Mother’s education PHOTOS: JANELL KLEBERG was perhaps limited to the second-grade level, so she was functionally illiterate. Dad attended high school. Still, they were very intelligent people who knew the value of education and the difference it could make in the lives of their children. Our roots were Hispanic, and we were raised in the Hispanic traditions and language but taught always to have deep loyalty to the United States. Dad and Mother spoke Spanish to each other. However, from the time we were very young, there was a rule that we children speak English to Dad and Spanish to Mother. And so we followed their directions, all their lives. We children usually spoke English to each other, but the working language of the ranch was Spanish. The first bilingual press conference held by a Cabinet officer occurred because I spoke two languages. At my first press interview after I became secretary of education, most of the questions were in English, but the Latino networks were there and asked their questions in Spanish. I responded in Spanish and translated for the rest of the press corps. One of the journalists from the Hispanic media asked what message I might have for Hispanics. I replied, “Niños, por favor, no dejen la escuela” (Children, please stay in school). HUNGRY WANDERER Our house was less than a quarter-mile from the highway. Often people driving through the ranch entered by the gate near our house, stopping to ask for directions, or food or work. The economy was desperate. The depression was at its height, and jobs and money were scarce. Mother was quite willing to give directions or provide food for a needy person or family. She made it a rule to never turn anyone away who asked for food. Mother told me that one morning, as she was cleaning the living room, she glanced out the window and saw a man approaching. She did not recognize him. His clothes were ragged and dirty, and he looked like a tramp. Mother was certain the stranger was up to no good, so she reached into the closet and got one of Dad’s pistols. They were always loaded. She told us children to stay together in the main bedroom, to be quiet and not to come out. Mother held the pistol behind her back. When [the stranger] knocked, she kept the screen door locked but opened the door. He winter 2007 t u f t s m e d i c i n e 31 looked at her, appeared somewhat startled, mumbled a few words Mother could not understand, backed off, turned around and quickly went out the front gate. The last she saw of him, he was headed for the highway. Then she realized what had happened. There was a large mirror on the wall behind her. The man must have seen the reflection of the pistol in the mirror, and he was scared off. I asked Mother if she had been frightened. She said she was, but most of all she worried about her children and herself. That was the only time I remember a threat of any kind in all the years we lived on the ranch. Who knows? The man coming to our door may not have been a troublemaker. He may have been hungry and looking for a meal, but realizing he faced a woman holding a pistol behind her back and with a determined look on her face, he must have lost his appetite. SOME BOOTS TO POLISH Dad worked on the ranch seven days a week, year after year. He took half of the day off on Thanksgiving and all of Christmas Day. There was never a vacation for him or for King Ranch yearlings 32 t u f t s m e d i c i n e winter 2007 Mother. Work and family consumed the entire calendar. Dad left the house about 4:30 a.m. every day. He was up early, bathed daily and had coffee. He was gone before I even stirred in the morning and did not return until after dark. By then you could not see to work cattle, so it was home to dinner. Dad always wore boots. I never saw him in a pair of shoes. He changed boots every day, just like most men change their shirt daily. Some pairs Dad wore only for daily work on the ranch, and others, his dress boots, were for special occasions. Dad’s boots were not ordinary, off-the-shelf boots either. A boot-maker named Rios down in Raymondville made them for him. Rios was well known for high quality boots, and he made many pairs for ranch notables throughout Texas, the Southwest and Mexico. They were exquisite. [My brother] Dick and I had the job of saddle soaping and polishing Dad’s boots every Saturday. The idea that he could work cattle in unpolished boots must never have occurred to him. So, for Dick and me, polishing boots was a Saturday ritual. On Saturday morning when Dick and I stepped out on the back porch, there were at least six pairs of Dad’s boots lined up awaiting our attention. Mother did her part by reminding us we had to polish Dad’s boots. There was to be no debate or discussion, no escaping the job. Some evenings Dad came in from working cattle in stormy, raining weather, his boots muddy and soaking wet. Dad would ask Dick and me to take care of the muddy boots immediately. It was a job that could not wait till the next day. We scraped off as much of the mud as we could and took the boots to the washhouse, where [our ranch hand] Vallejo stored 50-pound sacks of grain to feed our chickens. We filled each boot to the top with grain. When filled with grain, the boots would not shrink as they dried. The next day, if the boots were dry, the grain was emptied out of the boots and back into the feed sack. Nothing was wasted, and Dick and I had another pair of boots to polish. BASIC SCHOOLING In the 1930s there were no kindergarten classes on the ranch. Therefore, by the time n Saturday morning when Dick and I stepped out on the back porch, there were at least six pairs of Dad’s boots lined up awaiting our attention. I was four years old, Dad had tried to teach me the alphabet and how to count. I was not a scholar, and my preparation to start school “ready to learn” was minimal. When I turned six years old, however, it was off to school, where I joined my sister, Sarita, a third-grader. The school was about a mile from our home. Mother usually drove us to school, but sometimes we walked. The school building was wooden and was one room split into two classrooms by a portable divider. The schoolhouse had windows on three walls. To young people, the windows provided a major distraction because they gave us a grand view of activities around the ranch headquarters. Although the winters are mild in South Texas, the schoolhouse was cold and drafty. It was not insulated, and a small wood stove in the back of the room provided heat. At the noon hour we were dismissed to go home for lunch. There was not a blade of grass in the schoolyard, and only one large mesquite tree and a couple of live oak trees. Two privies, one for the boys and one for the girls, stood in back of the schoolyard. As we went out to recess, invariably the teacher would tell us to be careful and to watch where we stepped, because there were plenty of rattlesnakes. During my time at the Santa Gertrudis School, I received a fundamental education. I learned how to read, write and do basic mathematics, and I learned basic geography and history. Discipline was never a problem for the teachers, for we knew better than to misbehave. I went to school on the ranch for two years, and although we continued to live on the ranch, my parents then moved me to a school in Kingsville. I believe that the most important decision about my education was made when my parents decided that their children should be educated at the Flato Elementary School in Kingsville. Flato was about three miles from our home on the ranch. The Flato School was an impressive building. In the 1930s, elementary or “grammar” schools generally had seven grades, and high school had four grades. Thus, I had an 11-year elementary- and secondaryschool education in contrast to the 12 grades plus kindergarten most school districts offer today. The building was stucco and had two wings and a central portion. The first, second and third grades were in one wing, and grades four through seven were in the other wing. The one-room library and the principal’s office connected the wings. The halls along the wings had balconies, and the floors were wooden and highly polished. When Sarita and I arrived at Flato, Miss Ruby Gustavson was the principal. She was the principal from 1935 until her retirement in 1970 and as a result knew thousands of students from Kingsville. Miss Gustavson was an attractive woman with light brown hair and blue eyes. I remember her as about six feet tall. An imposing figure, she had great poise. Her speech was rather soft, but precise. There was never any doubt in our minds what Miss Gustavson meant when she asked us to do something for her. Miss Gustavson was a wonderful teacher and administrator who knew every student in school. Applying a fundamental tenet of education—involving parents in the education of their children—she made it a point to visit the homes of her students. I remember seeing her come to our house in Kingsville and telling Mother how Sarita and I were doing in school. I knew I was doomed. A discussion of my educational progress (or lack thereof) at Flato was bound to be bleak, with perhaps a few bright spots. THE DEBT OWED Miss Gustavson was an educational constant in my life. All through elementary school, she watched and encouraged my education. Frequently, she told me I could do better in school or praised me when it was clear I understood the lesson. As a principal, she found time to be not only an administrator but also a teacher and friend to every child in Flato. After I left Flato for high school, I occasionally stopped by for a visit. After I graduated from high school in 1944, I joined the Army. When I was home on leave, I asked Mother about Miss Gustavson, and she said she was fine and still principal. Miss Gustavson finally retired in 1970. For a time I lost track of her, but in 1981, when I was president of Texas Tech University, I gave a brief speech in Kingsville. Miss Gustavson was there, and I was very pleased to see her. Although she had aged a bit and used a cane, she still stood straight and gracefully, and her speech, as always, was precise and proper. We had a brief visit. The next time I saw Miss Gustavson was soon after my appointment as U.S. secretary of education. The first formal speech I gave after my appointment was in October 1988 on the campus of Texas College of Arts and Industries in Kingsville (now Texas A&M University–Kingsville). I do not recall the topic of my talk, but the highlight for me was seeing Miss Gustavson again. Prior to my speech, we talked briefly about education, but she wanted to talk about me. I could not get her to talk about herself; it was always about her students. Miss Gustavson told me how proud she was I was giving leadership to education in this country as secretary of education. She told me she had to admit she never dreamed I would be in the president’s Cabinet. I told Miss Gustavson that she and my parents placed me on the path of learning. I owed her and them so much. As I began my speech, I saw her on the left front row of the auditorium, where they had reserved a seat for her at my request. To the audience, I acknowledged her presence and told them of my debt to Miss Gustavson for the education she initiated in my life. I said that I asked but one thing from her: not to tell the press what a terrible student I was at Flato. I remember her smile as she shook her head. The author, professor of public health and family medicine, was dean of Tufts Medical School from 1975 to 1980, following a term as acting dean from 1973-75. Excerpted from A Kineño Remembers by Lauro F. Cavazos, copyright 2006. Published by Texas A&M University Press. Used with permission. winter 2007 t u f t s m e d i c i n e 33 ON CAMPUS ME D I C A L S C H OO L N E W S Institute of Mental Health, Dr. Ellen C. Perrin, professor of pediatrics at Tufts, and her colleagues will evaluate the effectiveness of their Advanced Parenting Education Program in nine pediatric practices and three urban health centers in eastern Massachusetts. Pediatricians will give parents a short questionnaire to screen their two- and threeyear-olds for elevated impulsivity, aggression, oppositionality (willfulness) and diminished attention. Dr. Ellen C. Perrin and her research team will determine if educating parents of toddlers with significant behavior problems can prevent an ADHD diagnosis later on. ADHD intervention Researchers will test parenting education program in pediatric practices by Jacqueline Mitchell most toddlers go through the “terrible twos,” the developmental stage marked by temper tantrums, willfulness and aggression. But researchers have found that children with significant behavioral problems at this young age are at increased risk of developing Attention Deficit Hyperactivity Disorder (ADHD) later on. ■ Researchers at the Floating Hospital for Children are evaluating one possible intervention. By teaching parents of at-risk toddlers advanced parenting strategies, they hope to improve children’s behavior problems at a young age, thereby reducing their risk of developing ADHD or another behavior problem, Oppositional Defiant Disorder, characterized by uncooperative and hostile behavior. ■ With the support of a $3.3 million grant from the National 34 t u f t s m e d i c i n e winter 2007 NASCENT EVIDENCE “We’re not making any diagnoses,” says Perrin, director of the Floating Hospital’s Division of Developmental-Behavioral Pediatrics and of the Center for Children with Special Needs. “We’re screening for early evidence of the kinds of behavior that eventually might lead to a diagnosis” of ADHD or Oppositional Defiant Disorder (ODD). Parents of kids with these behaviors will be invited to join a parenting education program. Based on the well-tested “Incredible Years” program developed by psychologist Carolyn Webster-Stratton, the education program gives parents guidelines for reducing their children’s aggression and behavior problems and increasing their social competence. Though Incredible Years has a proven track record, it’s never been tested in clinical pediatric settings before or with children at such a young age. The parenting groups will meet for two hours each week at the pediatric offices where two instructors—one a member of Perrin’s team, one an office employee—will present the course in 10 sessions. To measure parents’ success with the program, they will fill out self-assessment forms, and three times during the 10 sessions, they will be video-taped interacting with their children under a set of structured circumstances. “It’s a snapshot, but it does seem to represent the reality of children’s interactions with their parents,” says R. Christopher Sheldrick, assistant professor of pediatrics and the project’s primary co-investigator. THE POWER OF THE GROUP To perfect the methodology for the trial, Perrin’s team conducted a three-year feasibility study in one suburban practice and PHOTO: JODI HILTON one urban health center. Jannette McMenamy, assistant professor of behavioral science at Fitchburg State College, helped design the original project and instructed one of the parenting groups in Leominster, Mass. “I’m completely amazed by the power of the group,” says McMenamy, who remains involved in the project as a coinvestigator. “The whole equals more than the sum of its parts. When [parents] meet other parents in the same boat, the stigma decreases; the anxiety and the stress decrease.” The research team also hopes to demonstrate that the program decreases the economic burden of ADHD and other disruptive behavior problems on the healthcare system. Though statistics vary widely, the National Institute of Mental Health estimates that ADHD affects five to 10 percent of children. That’s some two million American school kids, or about one child in every classroom in the country. “Our belief is there could be some savings,” says Perrin, who believes that parents who have gone through the program will be less likely to seek mental health counseling for their children. There is evidence that depressed and distressed parents take their children to hospital emergency rooms and the doctor more often than parents who are more content and have better support systems. Though the researchers acknowledge that maintaining the program after the study will incur some cost to the pediatric practices—while saving parents and insurers money—their hope is that the educational model will remain in the pediatric practices long after the five-year study ends. “Anybody can do this. It’s not magic,” Perrin says, noting that the program is designed so that when the study is completed, the pediatric practices “can do these [parenting] groups just as we do them.” If the parenting education program is successful, Perrin hopes public funding or insurance reimbursement will make it economically viable in pediatric practice. But the team’s main goal is to learn whether parent education alleviates—and possibly even staves off—the impairments kids with ADHD and ODD experience. PHOTOS: KRISTEN OLSON WHI TE CO AT CEREM ON Y In early September, Dean Rosenblatt addressed first-year students and their parents in the Cutler Majestic Theatre at Emerson College. At left, students await their moment. This year’s featured speaker was Donald Vereen, Jr., M.D./M.P.H., ’85, special assistant to the director and medical officer at the National Institute on Drug Abuse. Zucker prizes Aviva Must, Ph.D., professor of public health and family medicine, and Abraham “Linc” Sonenshein, Ph.D., professor of molecular biology and microbiology, are the recipients of the 2006 Zucker Research Prizes. Must was awarded the Milton O. and Natalie V. Zucker Prize, given to a woman scientist for outstanding research. She studies the epidemiology of obesity, focusing on its long-term physical and psychosocial consequences. Sonenshein, whose research focuses on gene transcription regulation in spore-forming bacteria, received the Zucker Family Prize, which also recognizes outstanding research. winter 2007 t u f t s m e d i c i n e 35 ON CAMPUS ME D I C A L S C H O O L N E W S L AP T O P L O A N E R S WALK AROUND, FIND A SPOT AND PLUG IN. Since early this fall, that’s been the drill at the Hirsh Health Sciences Library, which has been loaning laptops to students who prefer the light, portable option. “All our computers are heavily used,” explains Eric Albright, library director, “and the laptops work well for those students who want to check them out and settle into a comfortable nook somewhere around the library.” These laptops don’t travel far; for security reasons, their use is restricted to library premises. Concerns about durability led the library to select IBMs that were neither the cheapest nor the most expensive model. The IBMS come with a sturdy carrying case that protects them from damage in case they get dropped now and then. “They can take more abuse than a cheaper model,” says Albright, who sees the purchase of the first five laptops—at about $1,500 each—as reflecting the library’s desire to be responsive to a variety of learning styles. Albright has already ordered another five laptops. “I’ve had two people come up and thank me for doing this, and you never get thanked for anything,” laughs the director. Breast cancer work charlotte kuperwasser, ph.d., assistant professor of anatomy and cellular biology, has been awarded a $200,000 grant from the Breast Cancer Research Foundation. The funding will support her research on the role of estrogen in cells other than breast carcinoma cells. Kuperwasser seeks to identify the bone marrow cells that are the target of estrogenmediated angiogenesis and tumor promotion, and to determine how these cells may respond to estrogen. Kuperwasser theorizes that a better understanding of estrogen’s effect on bone marrow cells, as well as on stromal fibroblasts and endothelial cells, could lead to anti-estrogen breast cancer therapies. Charlotte Kuperwasser C O U R S E D I R E C T O R N AM ED Ralph Aarons, M.D., Ph.D., assistant professor of pediatrics, has of one of three Educational Strategic Planning working groups. In been appointed course director of the Problem-Based Learning his new role, he will broaden faculty participation in PBL mentor- (PBL) Program at the medical school. ing activities and will guide PBL’s transition into the school’s new Aarons, who succeeds Luisa Fertita, M.S., R.N.C., has been actively involved in the school’s educational program since he began serving as a PBL facilitator in 1998. He also is a member 36 t u f t s m e d i c i n e winter 2007 curriculum. Aarons is a neonatologist at Caritas St. Elizabeth’s Medical Center and associate chief of the Division of Newborn Medicine. PHOTO: MARK MORELLI, ILLUSTRATION: ELVIS SWIFT Hail to the chief M EET THE CLA SS OF ’ 1 0 Dr. Joseph Corkery, assistant clinical professor of medicine, has been appointed chief medical officer of the Lahey Clinic, overseeing Lahey’s quality and safety programs and leading the hospital’s efforts to advance evidence-based medicine and improve patient outcomes. He has been a member of Lahey’s Board of WHO THEY ARE Completed applications Admitted Enrolled 6,694 453 171 Trustees since 1993. PROGRAM ENROLLMENT NEW DEAN janet hafler, ed.d., has been appointed dean for educational development in the Office of Educational Affairs. Hafler has been at Harvard Medical School for the past 17 years, most recently as director for faculty development and associate professor of pediatrics. At Harvard, she ran an active research program, applying qualitative research methods to medical Janet Hafler education. Hafler will bring her extensive expertise to many areas of curriculum development, evaluation and scholarship as the medical school develops and implements its educational and strategic plans. The main focus of her work will be on faculty development throughout the school’s programs, including admissions, problem-based learning, standardized patient care and clinical teaching. M.D. M.D./M.P.H. M.D./M.B.A. M.D./Ph.D. M.D./M.S.E. 140 16 8 4 3 MEAN GRADES Total GPA Science GPA 3.61 3.56 TOP FEEDER SCHOOLS Tufts Brown BC UMass Penn Cornell Brandeis MIT Berkeley Colby BU Holy Cross Harvard 29 13 11 10 8 8 8 6 5 4 4 4 4 WHERE THEY CAME FROM Other 19% Massachusetts 44% California 10% New Jersey 4% New York 13% Other New England states 10% winter 2007 t u f t s m e d i c i n e 37 The Sharewood Project held its 10th anniversary online auction in late November, raising nearly $8,000 to support its work providing free medical care to underserved populations around Boston. Some 100 bidders participated in the auction. HAFLER PHOTO: JODI HILTON; SHAREWOOD: JOANIE TOBIN UNIVERSITY NEWS THE WIDER WORLD OF TUFTS Al-Walid I El-Bermani teaches anatomy to students. Two medical school faculty members are among the first group of CELT fellows. New center will help faculty teach to a diversity of learning styles By Marjorie Howard brought PACE to Tufts and has augmented it with a new university-wide program: the Center for the Enhancement of Learning and Teaching (CELT), which will draw on research at PACE. when arts & sciences dean robert sternberg took his first college psychology course, he got a C—not an auspicious start for someone who eventually earned a Ph.D. in the field. The problem, he recalled more than 30 years later, was that his tests were all based on what students could memorize, and Sternberg is lousy at memorization. To add insult to injury, most of the material he had to learn isn’t even being taught in psychology anymore. Sternberg may not have fared well on tests that relied on good memorization skills, but he did do well on tests that involved creativity or verbal ability. “I can tend to be very good in writing, but I’m relatively poor in spatial visualization, so in my life, I capitalize on my verbal skills: I write a lot of articles, read a lot, give a lot of talks,” he said. “But I bought a GPS system for my car, and I always make sure that I have verbal directions when I go to a place because I don’t read maps that well. Nobody is good at everything, and people have to learn how to make the most of their strengths and get by—either by compensating for or correcting weaknesses.” Sternberg’s longstanding interest in different styles of learning resulted in his founding the PACE Center at Yale University, where he taught before coming to Tufts a year ago. PACE, which stands for Psychology of Abilities, Competencies and Expertise, advances the notion of abilities as modifiable and capable of development over a lifetime. Now Sternberg is taking his scholarship one step further. He has THE FIRST 12 FELLOWS CELT will help faculty members become better teachers through seminars, newsletters, discussions and workshops. “It’s not that we are saying people here don’t know how to teach,” said Sternberg, who is CELT’s director. “The goal is to enhance already good or even excellent teaching skills. We’re saying no matter how good you are you can always be better.” The signature program of the new center will be a weekly seminar for faculty fellows led by Molly Mead, the Lincoln Filene Professor at Tisch College, and Linda Jarvin, CELT’s deputy director, who did research in psychology and education at Yale before coming to Tufts. A group of 12 fellows from across the university will participate in the first seminar, starting in January. Participants either will be granted a stipend or given a one-course reduction in their teaching loads. Dr. David E. Ricklan, assistant professor of pathology, and Dr. Scott J. Gilbert, assis- Out of the box 38 t u f t s m e d i c i n e winter 2007 PHOTO: MELODY KO tant professor of medicine, are among the first group of fellows, chosen from a university-wide pool of 36 applicants who described challenges they are facing in the classroom. One faculty member wrote that he’d like help in making a dry, fact-based, introductory course more interesting; a second is planning to team teach and wants help in establishing the course. Sternberg said that while some students learn analytically, others may learn more practically or creatively. The idea, he said, is to “teach kids in varied ways so that at any given time, some are capitalizing on strengths and others are remediating weaknesses. The fellows will be encouraged to use this principle in at least one course they teach. They will bring actual teaching materials to the seminars and see how they can be improved to reach a diversity of learners.” “We’re not offering remedial training,” Jarvin said. “We’re not saying people don’t know how to teach and that we have to revamp the system. But we want to offer opportunities to faculty to think about their teaching and to enhance their teaching.” DUAL MISSION While PACE has been funded primarily with grants, CELT’s funding comes from a seed grant from the Office of the Provost as well as a $250,000 grant from the Davis Education Foundation of Falmouth, Maine. “Our dual mission as a university is teaching and scholarship,” said Jamshed Bharucha, provost and senior vice president. “At Tufts we pride ourselves on valuing both. Even as we advance our research and scholarship, we must continue to strive for excellence in teaching and renew ourselves as teachers in light of new research on the process of learning, rapid developments in the fields we teach, changing demographics of our students and new technology.” Bharucha said Associate Provost Mary Lee will work on behalf of his office to encourage all campuses to participate in the new center. Anne Gardulski, associate professor and chair of geology and one of the first fellows, said she sometimes teaches courses of 70 to 125 students and is trying to find ways to better assess students in such a large course. “One of the huge challenges in such courses is to construct exams or other assessment tools that indeed test what the students have learned,” Gardulski said. “Some students can respond well to essay questions, others to short answer tests, and others may have completely different ways of learning that traditional exams cannot evaluate. CLASSROOM CREATIVITY “I am looking for ways to be more creative in devising exams, although there are time constraints imposed by the fact that I do not have teaching assistant or grad student help for grading, thus I cannot offer essay exams,” she said. “I also want to ensure that I am requiring students to think about the science. Graphs, maps, charts and other representations of data are an integral part of science, so I feel I need to include these mechanisms for data work on exams. Ultimately, I suspect I will want to modify how I teach so that I can be more creative and develop new ways to assess how students are synthesizing the material.” Louise Maranda, who teaches biostatistics at the Cummings School of Veterinary Medicine, applied for a fellowship, in part, she wrote in her application, to try to find ways to reach students who come into her course with different backgrounds and at different levels. She said she hopes to learn how to assess her students’ prior knowledge, how to better develop lecture topics, and “understand the learning process to better develop fun, meaningful and efficient examples, homework and exams.” Jarvin said the center also will serve as a central clearinghouse for information about teaching initiatives. “There really isn’t a space for faculty members, especially those who are very committed to their teaching, to reflect on these practices and meet with other faculty to discuss them,” she said. L EE A S S UM ES NEW, WI DER ROL E ASSOCIATE PROVOST MARY LEE, J75, M83, WILL BE MOVING TO THE PROVOST’S OFFICE full-time, starting in January. For the past five years, Lee has done double duty as associate provost and dean for educational affairs at the medical school. Lee completed her residency in internal medicine at Tufts-New England Medical Center and was hired by Dr. Sheldon Wolff in the Department of Medicine to run the internal medicine clerkships. Since then, she has worked both as a clinician at Tufts-NEMC (until 2004) and as an administrator at the school, most notably as dean for educational affairs over the past 12 years. In her tenure as dean, Lee has helped to promote a culture of teamwork and collaboration. “Mary Lee has been a legendary dean for educational affairs at the medical school,” said Dean Michael Rosenblatt. “Her innovations in curriculum and information technology have put Tufts Medical School in a leadership position in medical education. Few educators, no matter how talented, are known beyond their institution. Mary is recognized internationally for her achievements.” In her new role, she will be focusing on providing university-wide leadership on several fronts, including the library system, educational resources and faculty development. “Among the educational resources she will be increasingly engaged with is the Tufts OpenCourseWare project, which has been a tremendous success,” said Provost Jamshed Bharucha in announcing the change. “Through this project, our educational resources are being accessed by tens of thousands of people across the globe. OCW promises to become a signature program for Tufts as Mary focuses more time on it.” winter 2007 t u f t s m e d i c i n e 39 BEYOND BOUNDARIES P R O V I D I N G T H E M E A NS F OR E XC EL L E NC E Fund-raising effort is part of university’s historic $1.2 billion campaign A $225 million goal the school of medicine is seeking to raise $225 million as part of a five-year university-wide $1.2 billion fund-raising campaign, the largest in Tufts’ history. Beyond Boundaries: The Campaign for Tufts was officially launched on November 3 at Boston’s Wang Center. The fund-raising endeavor, which seeks to raise double the amount of the university’s last capital campaign, targets key priorities such as financial aid, endowed professorships, research facilities and initiatives in citizenship and public service. Sixty percent will be directed to the Tufts endowment, which now stands at $1.2 billion. “Building upon our strength and reputation as a premiere medical school, we are committed to preparing the institution to meet the challenges and seize the opportunities presented in this dynamic period of scientific discovery and medical care,” said Dean Michael Rosenblatt. 40 t u f t s m e d i c i n e winter 2007 “A successful campaign will enable us to continue admitting the finest students, to attract and return the best faculty.” Highlights of the campaign for the medical school include: Scholarships. When students choose Tufts Medical School, they shoulder tuition that is one of the highest in the nation. The campaign seeks new gifts and pledges totaling $65 million to bolster scholarships and stipends so that outstanding students may have the opportunity to pursue medical and biomedical graduate education. The goal PHOTO: MELODY KO will fulfill a critical need to endow 80 halftuition scholarships for students in the School of Medicine and 40 stipends for first-year Ph.D. students in the Sackler School of Graduate Biomedical Sciences. Teaching hospital partnerships and clinical faculty. More than 2,000 skilled, voluntary clinical educators at 14 affiliated Tufts teaching hospitals devote uncompensated time, often at the expense of their practices, to train the next generation of physicians. The campaign seeks funding to support this vital experience by raising $10 million to support a “Community of Clinical Educators.” This initiative will reward the contributions of outstanding clerkship directors by providing financial support to the directors of the five core clerkships. In addition, to recognize and retain outstanding clinical leadership, the school will earmark $9 million to strengthen funding for clinical department chairs by endowing professorships for three or more clinical department leaders. A NEW WAY TO S UPPOR T THE UNI VERSI TY Y OU LOV E Are you 70 1 ⁄ 2 years of age or older? Are you required to take distributions from your IRA (Individual Retirement Account) that you don’t need? Until December 31, 2007, you can make a donation to Tufts University School of Medicine by directly transferring money from your IRA, tax free. The Pension Protection Act of 2006 allows individuals with traditional or Roth IRAs to make tax-free charitable distributions in any amount up to $100,000 per year. To make your gift and for more information, please visit www.tufts.edu/giftplanning, or contact the Gift Planning Office by phone at 1.888.PGTufts or by e-mail at giftplanning@tufts.edu. Please note that this information is not intended as legal advice, so please consult with your tax advisor if you are considering this type of gift. Restrictions may exist. Research and basic science faculty. The school will make targeted investments toward achieving distinctive capabilities in four research areas: infectious disease, neuroscience sensory and disease biology, cancer and heart disease. Funding will also be focused on elevating the school’s expertise in “platform” fields of study: genetics; clinical research and evidence-based medicine; drug discovery and development; and regenerative and stem cell medicine. Some $25 million of the school’s campaign goal will benefit distinguished basic science research faculty. This goal will translate into five full professorships and 10 assistant/associate endowed professorships. In addition, the school seeks science faculty recruitment packages to attract talented investigators who translate scientific discovery at the bench to the bedside. Recruit- Robert Goldstein, a student in the medical school’s combined M.D./Ph.D. program, conducts research on the health sciences campus, where research facilities to support investigations into infectious disease and other issues of importance are a campaign priority. ment packages include start-up funds, lab renovations and salary support for three to five years. Campus identity and educational facilities. The school aims to raise $31 million for a campus center. The facility will include a cafeteria to foster daily student and faculty interaction, a large function space for ceremonies and other events and space for students to meet. Due to the growing use of technology in medicine, the school also will construct a network of simulation centers on campus and at teaching hospitals. The Medical Skills and Simulation Center will require $23 million in funding. To create a distinctive campus setting, $5 million is needed for Tufts University School of Medicine signage, expanded lighting, improved walkways and a well-integrated landscape architecture. The Fund for Tufts Medicine. Already one of the strongest-performing medical school annual funds in the country, the Fund for Tufts Medicine is experiencing unprecedented growth, thanks to the generous and visionary support of alumni, parents and friends. The annual fund touches every aspect of education and research at Tufts and will remain a cornerstone to our success. The campaign seeks to raise $14 million in annual funds. The medical school’s campaign, said Rosenblatt, is an opportunity to celebrate the achievements of the school and to heighten the important role of philanthropy. Throughout the course of the effort, he will be meeting with alumni and friends to talk about how Beyond Boundaries will transform the school. “Philanthropy has always been a critical part of the medical school’s progress,” Rosenblatt said. “We are grateful that the level of support has been steadily growing, both sustaining and strengthening our preeminence. We still, however, have much to do to ensure that our excellence in education and research meets the enormous needs of a rapidly changing world. I’m excited by our prospects, and I hope others will be too.” For more about Beyond Boundaries, go to www.tufts.edu/giving. winter 2007 t u f t s m e d i c i n e 41 BEYOND BOUNDARIES P R O V I D I N G T H E M E A NS F OR E XC EL L E NC E Open to the world Students gain public health experience in developing nations By Mark Sullivan dr. harris berman was on duty in a New Hampshire emergency room in the middle of flu season a few years back when an Indian man arrived complaining of aches and fever. Something about the man’s symptoms led Berman, a former Peace Corps physician in India, Nepal, Fiji and Western Samoa, to do some additional tests—and indeed, the man was found to be suffering from malaria. “His case easily could have been passed off as the flu,” recalled Berman, now the Morton A. Madoff Professor and chair of Public Health and Family Medicine and dean of public health and professional degree programs at the medical school. The global travel that has made ours a small world also has increased the chances that a tropical disease will turn up in a New England emergency room, Berman said. A new initiative launched by his office trains medical students to spot diseases from around the world by sending them out into 42 t u f t s m e d i c i n e winter 2007 the world. The Global Health Initiative includes student clerkship opportunities in developing countries and a new global health concentration in the master’s program in public health. “These exciting new programs are being established to respond to the needs expressed by our students, to learn and experience public health and medical care in a global setting,” said Berman, who is now working to attract philanthropic support for the initiative. “As the world becomes much more of a global community,” he continued, “the diseases of the developing world travel to our borders in a matter of hours, and the diseases of developed countries are becoming more common in the developing world. These new programs will deal with these important issues and add an important dimension to the education at Tufts.” Fellowship programs began this past summer. Several opportunities are available for students in the M.D./M.P.H., D.V.M./M.P.H., M.P.H. and M.S. in health communications degree programs: ■ In Panama, under a partnership with the School of Medicine at Panama University, student fellows will divide their time between language school, with an emphasis on medical Spanish, and a community health center. ■ In East Africa, students will work on public health and environmental projects at the Institute of Public Health at Makerere University in Kampala, Uganda, and at the School of Public Health at Muhimbili University College of Health Sciences in Dar es Salaam, Tanzania. Students also will assist faculty at the participating institutions to link with Tufts via TUSK (the Tufts University Science Knowledgebase). The project will be expanded next year to the Christian Medical College in Vellore, India. ■ In Mangalore, India, student fellows will gain community health experience under a collaboration with Father Muller Medical College. ■ The Hickey-Peyton International Travel Fellowship is awarded annually to firstyear medical students to support public PHOTO: MICHEL DE NIJS FOR ISTOCKPHOTO.COM health research and activities in a foreign country of their choice. ■ The new Global Health Concentration to be introduced in the M.P.H. program in September 2007 will entail four global health courses in addition to core degree requirements. L E TTERS FROM A BROA D This past summer, six students traveled to India under the Global Health Initiative, while seven traveled to Panama and seven went to East Africa, Berman said. Since their return, the students have made presentations on their experiences to medical school classmates and alumni, to Tufts University’s international overseers and to the medical school’s overseers. Already, one alumnus inspired by their accounts has pledged to sponsor a student traveling to Vellore, India, this winter, Berman said. Six M.D./M.P.H. students are slated to do their practicum in public health at the Christian Medical College there in February and March. Each student is given a stipend of $2,500. Right now, the initiative is being funded on a year-to-year basis, Berman said. “What we need is about $100,000 a year to run the program,” he said. “What we really need is an endowment to run this in perpetuity.” Berman hopes potential benefactors see this initiative as an outstanding investment in global public health education and active citizenship. “They’ll be helping to expand opportunities for students, to spread good will for the United States at a time we really need it, and to make better doctors and public health practitioners,” he said. “These students who have seen the world will be better able to help the world when they become physicians and public health professionals.” Sarah Gottfried, ’09 “Each day brought a new experience. A new sub-health center to visit, new doctors to work with, new patients and some medical conditions we would have never seen here in the States. We got a true taste of general medicine, pediatrics and gynecology. We gained insight into the medical conditions that are common, that are seen every day all over the world, and those that are more unique to Panama. “Every time I perform the Leopold Maneuvers on a pregnant woman, palpate Gottfried in traditional garb with children of an abdomen for possible appendicitis, the Kuna Indian tribe of Panama look down a throat for exudate or deliver a baby, I will think of the patients in Panama who let this new, awkwardly bumbling Doctora Americana treat them.” www.tufts.edu/med/medissue/sacklerb/ panama.htm Mark Sullivan is a senior writer for Advancement Communications. If you are interested in sponsoring a global health student internship, or making a contribution to the Fund for Global/Public Health, please contact Joshua Young at 617.636.3604 or e-mail joshua.young @tufts.edu. Tufts medical students’ reports from the field best convey the flavor of the public health experience they have gained around the world through the Global Health Initiative. Some excerpts: Practicando la medicina en Panamá My summer in India Jessica Heath, ’09 “Weekdays were fairly structured. In the morning, we’d go to class. We were in twoweek rotations between general medicine, OB, pediatrics and surgery. Class consisted of a topical lecture followed by a trip to the general wards and a case presentation or a visit to the OR. On Thursdays we visited primary health-care centers that catered to rural and low-income patients. “This approach was a good way to get an overall perspective on diseases, especially those endemic to India, like leprosy, tuberculosis and malaria.www.tufts.edu/med/ medissue/sacklerb/india.htm The sadness of the developing world Anita Sarathi, ’09 “Sadness, helplessness, anger, guilt. All emotions I encountered in passing the street children of Kampala, Uganda. Although this was my first time to travel abroad, I had heard of these young children in the streets throughout the developing world. I had been warned by various American citizens not to hand out money to these children as a matter of safety. I felt as if this advice was more than a little heartless, but I kept it in mind nonetheless. I wondered at myself as I passed a small girl with a baby on her back. How could I just ignore this beautiful child? Who gave me the right, with all of my riches and blessings, to just walk on by? www.tufts.edu/med/medissue/sacklerb/uganda.htm winter 2007 t u f t s m e d i c i n e 43 ALUMNI NEWS S TAY I NG C ON NEC T E D Now more than ever tufts university has just launched a new capital campaign. As part of this campaign, the medical school has the ambitious goal of raising $225 million over the next five years. Consider just a few of the challenges and opportunities that we face: ■ Scholarships: The medical school always has been rich in ideas, with wonderful students and faculty. But for too long, our tuition has been very high (and for some, prohibitive). With an endowment that permits us to fund half-tuition scholarships for one-fourth of our students, we can attract and train a highly diverse student body, not just the privileged, well into the future. ■ Medical Skills and Simulations Center: Creation of this center would permit the school to integrate the recent breakthroughs in technology, digital art and game development into new, virtual-reality simulations for medical education. ■ Faculty Recruitment: These days, to be competitive in attracting and keeping world-class scientists and teachers, we need to be able to offer comprehensive recruitment packages. Several faculty members are now approaching retirement age. With new funding for recruitment of young scientist-teachers, we have a wonderful opportunity to build the school’s future faculty over the next eight to 10 years. ■ Curriculum Initiatives: A creative redesign of the medical school curriculum is under way. The new curriculum will have interdisciplinary, translational medicine as its common perspective and will teach our students to integrate cutting-edge basic science discoveries into the practice of clinical medicine. We all receive a number of philanthropic requests each year. But at this exciting time, the medical school needs you more than ever. Would you consider elevating your giving to Tufts to a higher priority this year? Please give serious thought to what you might be able to do to help us to take this giant leap forward in advancing medical education so that Tufts is poised to train the medical leaders of tomorrow. Many thanks. Betsy Busch, ’75 bbusch@verizon.net TRAVEL TO EXTRAORDINARY PLACES WITH EXCEPTIONAL PEOPLE From Antarctica to Santorini, from China to the Nile, the Tufts Travel-Learn Program combines intellectual inquiry with leisure and exploration. There’s a perfect trip for every taste. Call Usha Sellers, Director, at 800-843-2586 or visit our website for updated details and itineraries. travel-learn www.tufts.edu/alumni/ed-travel-learn.html 44 t u f t s m e d i c i n e winter 2007 PHOTO: BRIAN LOEB C LA SS N O TE S 47 Lawrence Coleman of Rindge, N.H., spends his free time working with the state’s Department of Environmental Services to prevent deterioration in his local community. Among his proudest lifetime accomplishments, he cites having assisted in the physiological testing of the lifesupport system for the “moon suit” used by astronauts in their first landing on the moon. Coleman and his wife, Ernestine, have a son, William, and a granddaughter, Sara. Salvatore Mangano of Hingham, Mass., writes that he is happily settled in a wonderful, carefree community by the sea. Together with Ted Gordon, he will be planning the 60th reunion for the Class of 1947. “Hope to see our classmates of the Golden Era at Tufts Medical School,” he writes. 57 Joel Berman of Southborough, Mass., who spends his time playing golf and bridge and taking postgraduate courses, is planning to attend his class reunion this spring. “Is it only 50 years?” he writes half-mockingly. “Seems more like 500!” Basil Pruitt of San Antonio, Texas, has been awarded an international prize for his outstanding contributions to the field of burn care, research and education. The Tanner-VandeputBoswick Burn Prize for 2006, named for three physicians prominent in the field, was presented to Pruitt in September at a global conference in Brazil. The award carries a cash value of approximately $100,000. “Dr. Pruitt was selected for his remarkable and enduring contributions to the field of burns,” said the chair of the International Burn Foundation, which awarded the prize. “He remains one of the most influential physicians in the field of burn treatment.” Ann Grumley Lester of Miami, Fla., jokes that having graduated from medical school in 1957 is her proudest medical accomplishment. More seriously, she notes that Tufts provided her with “a wonderful general background for general pediatric practice.” These days, Lester enjoys playing chamber music. 60 Robert D. Kennison, professor of obstetrics and gynecology, retired on December 31 after more than 40 years of service to Tufts-New England Medical Center and Tufts School of Medicine. Kennison became chief resident in gynecology at NEMC in 1964 and a teaching fellow in obstetrics and gynecology at the medical school. He has held positions at both institutions ever since, including several leadership roles in the hospital’s Department of Obstetrics and Gynecology and as part of the school’s administration, where he has played a key role in curriculum innovation. He is a past president of the Tufts Medical Alumni Association and a member of the University Alumni Council. A frequent recipient of teaching awards, Kennison won the medical school’s Zucker Teaching Prize in 2000. He is also a captain in the Army Medical Corps and served in the Womack Army Medical Center’s Department of Obstetrics and Gynecology from 1965-67 and in 1995. 62 Frank Calia of Grasonville, Md., is an internal medicine and infectious disease specialist at the University of Maryland School of Medicine, where he is the Theodore E. Woodward Professor of Medicine and chair of the Department of Medicine. He reports that students have named him Teacher of the Year at graduation for the past 24 years. Richard Gardner of Cape Coral, Fla., an orthopedic surgeon, has invented four medical devices now commonly found in hospitals around the world. One of these, the “Gardner Arm Elevator,” is a sling that has been used by both friendly and opposing forces to speed rehabilitation of soldiers during the military operations of Desert Storm, Desert Shield and Iraqi Freedom. Gardner and his wife, Ingrid, have two sons, Adam and David. 67 David Bass of Glastonbury, Conn., is a plastic and reconstructive surgeon in the Hartford area. He has volunteered repeatedly as a medical missionary to sites in the developing countries of Latin America, including Honduras, Bolivia and Peru, and plans to continue his service in the years ahead. John Buckley of Glen Arm, Md., writes that he is “still alive and still practicing” psychiatry. For fun, he says he tries to “patch the old house and avoid golf.” Buckley and his wife, Sharon, have four children and seven grandchildren. He asks classmates to stop by when they are in the Baltimore area. 71 Samuel Berkman of Encino, Calif., has written an historical novel, The American Student, about an American teenager’s struggle in Europe during the Berlin crisis. Excerpts and source materials from the book can be viewed on the book’s website at www.samuelberkman.com. 73 Arthur Fournier of Miami, Fla., associate dean for community health affairs and a professor at the University of Miami’s WE WANT TO HEAR FROM YOU! Have a new job? Is your family growing? A special project or appointment? Getting together with classmates? Keep your fellow alumni/ae posted by dropping us a line. Send to: Tufts Medical Alumni Relations 136 Harrison Avenue Boston, MA 02111 e-mail: medicine-alumni@tufts.edu CLASS NOTES DEADLINE FOR NEXT ISSUE IS MARCH 1, 2007 winter 2007 t u f t s m e d i c i n e 45 ALUMNI NEWS Miller School of Medicine, published The Zombie Curse (Joseph Henry Press, 2006), which recounts his 25-year journey into the heart of the AIDS epidemic in Haiti. Fournier has pledged to donate all author proceeds from the book to Project Medshare, a nonprofit organization dedicated to improving the health of the Haitian people. He can be reached at afournier@med.miami.edu. 77 David Geffen of Beer Sheva, Israel, is director of the oncology ambulatory care unit at Soroka Medical Center and serves on the faculty of health sciences at Ben Gurion University. He writes that he is proud to have helped establish a modern cancer treatment program for the residents of southern Israel. Geffen and his wife, Mitzi, have four children and three grandchildren. Patricia McShane of Breckenridge, Colo., is an ob/gyn specialist who served as medical director of the Reproductive Science Center in Lexington, Mass., from 1988 to 2006. She writes that she found a measure of satisfaction in “growing my practice over 18 years and bringing several new techniques into the program.” Norman Yanofsky of Hanover, N.H., is an associate professor of medicine and chair of the emergency medicine section at Dartmouth-Hitchcock Medical Center. He and his wife, Kathleen, have two sons, Benjamin, 19, and David, 17. 46 t u f t s m e d i c i n e winter 2007 CLASS NOTES 82 Daniel Driscoll of Milton, Mass., is a clinical assistant professor at Tufts and an instructor in community medicine at Boston University School of Medicine. He and his wife, Elaine, have four children, Matt, Alicia, Danny and John. “All is well,” he writes. “The first of four is off to college.” Connie Jackson of Chestnut Hill, Mass., assistant clinical professor of obstetrics and gynecology, recently joined the medical staff at Winchester Hospital and is practicing at Dowd Medical Associates in Reading. She previously worked as an obstetrician-gynecologist with the Southboro Medical Group. 89 Lisa Stellwagen of San Diego, Calif., is a specialist in newborn medicine at the UC/San Diego School of Medicine. She and her husband, Marc Montminy, ’84, have three children. Stellwagen writes: “Marc and I have been married for 22 years! He is doing molecular biology at the Salk Institute. We would love to hear from anyone who comes to San Diego.” Peter Rosenblatt of Newton, Mass., an innovator in the field of operative laparoscopy and pelvic reconstructive surgery, has been named chair of the newly formed Female Health Advisory Board at Andover Medical Inc. He has been director of urogynecology and pelvic reconstructive surgery at Mt. Auburn Hospital in Cambridge since 1995. 84 92 Marc Montminy, see ’82. John Donahue of Attleboro, Mass., is a neurologist on staff at Rhode Island Hospital in Providence, R.I., as well as an assistant professor of pathology and laboratory medicine at Brown Medical School. His favorite memory of medical school involves “doing surgery at St. E’s, even though I hated surgery and the long hours. It was a fun group of house staff and students.” 86 Robert Harrington of Apex, N.C., a cardiologist at Duke University Medical Center, has been named director of the Duke Clinical Research Institute, the world’s largest academic clinical research organization. Harrington was most recently the institute’s co-director of cardiovascular research and the leader of cardiovascular clinical trials. He joined the Duke faculty in 1993. 87 Anita Honkanen of Palo Alto, Calif., is chief of the division of pediatric anesthesia and director of anesthesia services at Lucile Packard Children’s Hospital at Stanford University. 97 Maria Rhee and her husband, Kory Tray, ’97, of Cheshire, Conn., are keeping busy. She works as a clinical instructor in ob/gyn at Yale-New Haven Hospital and has a private practice on the side. He is a nephrologist at Hartford Hospital and is also a partner in a medical practice. Together, they have three children under the age of six. “You can still work full-time and raise a family,” Rhee tells current medical students. “Don’t fret, ladies!” 02 Josh Riff of Tucson, Ariz., an emergency room doctor, suffered a bicycle crash that put him out of the running for the Ironman World Championship in Hawaii this fall—an event for which he was training when a pickup truck struck him, breaking his leg, in early October. Riff and his wife, Jennifer, are expecting their first child in February. “Someone once told me you can do a lot of things, but only three things really well,” Riff reflects. “The last few years, it’s been being husband, doctor and Ironman. Next year I’m going to be a dad, husband and doctor.” Karen Sullivan of Arlington, Mass., is working at Lexington Pediatrics in Lexington, Mass., and is affiliated with Children’s Hospital in Boston. Rakesh Talati of Wilbraham, Mass., is an assistant professor of emergency medicine at Baystate Medical Center. He writes that he has continued his interest in volleyball that he cultivated while a medical student. 03 Cathy Beland of Slingerlands, N.Y., has joined Martha’s Vineyard Hospital as an emergency room physician. Beland, whose interests include hiking and wilderness medicine, completed her residency at the Albany Medical Center in June. O BI TUAR I E S D'Agostino (center) with children from the Nyumbani Orphanage in 2004. “He reached out to everybody,” said a friend. Jesuit doctor founded AIDS orphanage in Kenya ANGELO D’AGOSTINO, S.J., ’49, OF NAIROBI, KENYA, WHO OPENED ONE OF THE FIRST orphanages for HIV-positive children in Kenya and fought to make AIDS drugs affordable to the poor, died November 20 of a heart attack. He was 80. D’Agostino trained in urology at Tufts-New England Medical Center, served in the U.S. Air Force as a surgeon and became the first Catholic priest to be a psychiatrist specializing in psychoanalysis. But his true legacy, his colleagues say, was built in a rented home in a suburb on the outskirts of Kenya’s capital city. He grew up in Providence, R.I., one of six children of Italian immigrants. His father, a construction worker, professed an antagonism toward religion. Despite this, two of the D’Agostino children became priests, another a Christian brother and one a nun. He attended St. Michael’s College in Vermont before entering medical school. During the Korean War, he joined the Air Force and worked in a military hospital near Washington. His calling to the priesthood began with a retreat led by a Jesuit priest. “I finally realized there was more to life than cutting up, and sewing up, people,” D’Agostino told the Washington Post. He was PHOTO: AP PHOTO/KHALIL SENOSI ordained in 1966. At the prompting of his Jesuit superiors, he trained in psychiatry at Georgetown University and the Washington Psychoanalytic Institute before traveling to Thailand to help set up a refugee camp in 1980. He went to Africa the following year. D’Agostino opened the Nyumbani Orphanage in 1992, when it welcomed three HIV-positive children. “He was mirroring the compassion of God. He reached out to everybody,” said Sister Mary Owens, who had worked beside D’Agostino for the past 14 years. Nyumbani is the Swahili word for “home.” With aid from the Jesuits and from fund-raising trips he made back to New England, D’Agostino, known around the orphanage as “Father Dag,” gradually expanded the site into a compound that cared for scores of children. At the time of his death, D’Agostino had just returned from Rome and the United States, where he was raising funds to support Nyumbani Village, a self-sustaining community to serve the orphans and elderly left behind from the AIDS pandemic in Kenya, where more than 1 million children have lost their parents to the disease. The goal of the village, which will include 100 houses, a school, a clinic and a community center, is to create new blended families for 1,000 orphaned children being cared for by their grandparents. In 2001, Nyumbani was the first place in Africa to import deeply discounted AIDS drugs. winter 2007 t u f t s m e d i c i n e 47 ALUMNI NEWS OBITUARIES BELOVED MENTOR, OBSTETRICIAN DELIVERED 15,000 BABIES PHILIP MCGOVERN JR., OF WINCHESTER, MASS., CLINICAL professor of medicine and chief of obstetrics and gynecology combining his professional efforts with Catholic Charities. Born in Cambridge, he graduated from Boston College at Cambridge City Hospital for more than 30 years, died on in 1951 and New York Medical College in 1959. McGovern October 20 after completing his last delivery at Mt. Auburn had lived in Winchester since 1963. In addition to his work at Hospital in Cambridge. He was 72. Cambridge City Hospital, he maintained a private practice at “He did what he loved, right up to the very end,” said Kate Harney, ’90, chief of obstetrics and gynecology and women’s health at Cambridge Heath Alliance, who had worked with Mt. Auburn Hospital and Caritas St. Elizabeth’s Medical Center. During his career, he delivered some 15,000 babies. McGovern was a beloved mentor to students at the McGovern since 1986. “What was so amazing is the way that medical school and had been awarded Professor of the Year he took care of every patient regardless of background or abili- for 17 years in a row. The award now bears his name. He is ty to pay.” McGovern was well known for referring patients survived by his wife, Kathleen, and by three sons, two who were financially struggling to places that could help by daughters and four grandchildren. Charles Bates, ’36, of Calais, Maine, died on April 1. His 43 years of medical practice included caring for the Canadian communities on Deer Island and Campobello Island and in the adjacent communities of Eastport, Maine. He was instrumental in reestablishing the Eastport Memorial Hospital in 1944, which had been closed during World War II. affairs. For more than 40 years, he was on the faculty of the University of Connecticut School of Medicine. He was a founder of the Connecticut Public Broadcasting Network. Albert Pearson, A39, M43, of Middlebury, Vt., died on November 10 at age 89. Born in Medford, Mass., he entered the U.S. Army following medical school and served as a captain in England, France and Germany, participating in the Battle of the Bulge. In the 1950s, following several years of practice in Vermont, he settled with his family in Mass- 48 t u f t s m e d i c i n e winter 2007 achusetts. Pearson retired in 1982. After he lost his wife, Priscilla, in 2004, he lived quietly with his daughter and her husband in Middlebury, where he was surrounded by love, basset hounds and cats, for the remainder of his life. He is survived by his daughter, a son, seven grandchildren and two great-grandsons. Bernard Krasner, ’45, of Scottsdale, Ariz., died on August 10. He is survived by his wife, Phyllis, and a son, Stephen. Harold Wetstone, ’51, of Bloomfield, Conn., died on May 24. He had a 35-year career at Hartford Hospital, including serving as director of outpatient clinics, director of the emergency room and vice president of corporate medical Julian Pearlman, A48, M52, of Lexington, Mass., died on August 23 at age 84. He had worked for 33 years at Lexington Pediatric Associates and was associated with Children’s Hospital in Boston throughout his career. Pearlman was born in Boston, the son of a pharmacist, and served in the Army Air Corps during World War II. After graduating from Tufts University and completing his medical training, he opened a practice in Lexington in 1955, which he operated for 16 years. There he became known for close, gentle attention to patients and their fami- lies. Pearlman loved sailing, the Boston Symphony and reading. He is survived by his wife, Dorothy, a son, a daughter and four grandchildren. Gilbert Klickstein, ’55, of Wayland, Mass., died on August 24. He was a surgeon at Central Michigan Community Hospital in Mt. Pleasant, Mich., from 1972 until his retirement in 2002. Klickstein is remembered by his medical colleagues in Mt. Pleasant as a caring, supportive surgeon with a strong sense of community. He is survived by his wife, Adele, two sons and three grandchildren. GREGORY CAMPBELL Look ahead & give back “ My wife, Esther, and I wanted to give something back to the academic institutions that helped us to achieve our professional goals. So, we both ” established charitable gift annuities to benefit our alma maters. DR. MICHAEL LEVINE, A56, M60, and Mrs. Esther Levine, of Atlanta, Georgia, have both established charitable gift annuities to benefit their alma maters. Dr. Levine is one of Northside Pediatrics’ longest-practicing physicians and also volunteers as a docent at Atlanta’s High Museum of Art. Mrs. Levine is considered a book maven and is president of Book Atlanta, Inc., a company that specializes in escorting authors when they are on national book tours. For information about charitable gifts annuities and other gift-planning options, contact Tufts’ Gift Planning Office toll-free at 1-888-748-8387 or via email to giftplanning@tufts.edu. Visit us online at www.tufts.edu/giftplanning. HEARTFELT MEDICINE PHOTO BY MELDOY KO Once she graduates, Candace Barnes, ’07, wants to be the best doctor she can be. The intensity of her listening to the case history presented by patient-actor Kia Scott shows that she is well on her way. Beginning on page 15, we look at how Tufts is teaching students to be more effective physicians, one patient at a time. School of Medicine NONPROFIT ORG. U.S. POSTAGE PA I D BOSTON, MA PERMIT NO. 1161 136 Harrison Avenue Boston, ma 02111 www.tufts.edu/med TUFTS UNIVERSITY OFFICE OF PUBLICATIONS 7463 1/07