for Research Use Only Active Pharmaceutical Ingredients
Transcription
for Research Use Only Active Pharmaceutical Ingredients
l a c i t u e c a m r a h P e v i t g o l Ac a t a C s t n e i d Ingre for Res y l n O e s earch U Index Index 1. Agents Acting on Central Nervous System n Anesthetic Agents. . ............................................................ 3 n Hypnotic Agents.. ............................................................... 3 n Antiepileptic Agents. . ......................................................... 3 n Antipsychotic Agents. . ....................................................... 4 n Anti-Anxiety Agent............................................................. 5 n Antidepressant Agents..................................................... 5 n Antimanic Agent. . ............................................................... 7 n Antiparkinsonism Agents. . ................................................ 7 n Anti-Alzheimer's Disease Agents.. .................................. 8 n Central Nervous System Stimulants. . ............................ 8 n Brain Metabolic Stimulants.............................................. 8 n Antipyretic Analgesics. . ..................................................... 9 2. Agents Acting on Somatic Nervous System n Local Anesthetics............................................................ 10 n Peripheral Muscle Relaxants........................................ 10 n Central Muscle Relaxants. . .............................................11 3. Agents Acting on Cardiovascular System n Antihypertensives.............................................................11 n Anti-Cardiac Failure Agents. . ......................................... 13 n Antianginal Agents.......................................................... 14 n Antiarrhythmic Agents. . ................................................... 14 n Antihypotensives............................................................. 14 n Antispasmodic Agent...................................................... 15 4. Agents Acting on Respiratory System n Anti-Asthmatic Agents.................................................... 15 n Expectorants.................................................................... 16 n Antitussive Agent............................................................. 16 5. Agents Acting on Digestive System n Antiulcer Agents. . ............................................................. 17 n Antacids.. ........................................................................... 18 n Emetic Agents/Antiemetic Agents................................ 18 n Antidiarrheal Agents. . ...................................................... 19 n Cathartic Agents.............................................................. 19 n Other Gastrointestinal Agents....................................... 19 6. Agents Acting on Endocrine Metabolic Disease n Lipid-Lowering Agents.................................................... 20 n Diabetes Agents.............................................................. 21 n Antigout Agents. . .............................................................. 22 n Anti-Liver Disease Agents. . ............................................ 22 n Diuretic Agents.. ............................................................... 23 n Choleretic Agents............................................................ 23 n Anti-Osteoporosis Agents.............................................. 23 n Anti-Pancreatitis Agents................................................. 24 n Antirheumatic Agents. . .................................................... 24 n Antidotes........................................................................... 24 7. Agents Acting on Urinary and Reproductive Systems n Urinary Organ/Genital Organ Agents.......................... 25 8. Agents Acting on Blood and Body Fluid n Anticoagulant Agents...................................................... 25 n Thrombolytic Agents....................................................... 25 n Antiplatelet Agents.. ......................................................... 26 n Antithrombin Agents. . ...................................................... 26 n Hemostatic Agents.......................................................... 26 9. Anti-Inflammatory Agents n Nonsteroidal Anti-Inflammatory Agents....................... 27 n Other Anti-Inflammatory Agents................................... 28 10. Anti-Allergic and Antihistamine Agents n Antiallergic Agents. . ......................................................... 28 n Antihistamines. . ................................................................ 29 n Antileukotriene Agents. . .................................................. 29 n Other Antiallergic and Antihistamine Agents.............. 29 All products are for research use only. 11. Hormonal Agents n Corticosteroids................................................................. 30 n Sex Hormones................................................................. 31 n Thyroid Hormone Derivatives....................................... 32 n Growth Hormones........................................................... 32 n Hypothalamus Hormones.............................................. 32 12. Ophthalmic Agents n Antiglaucoma Agents...................................................... 33 n Anticataract Agents......................................................... 33 n Mydriatics. . ........................................................................ 33 13. Antibiotics n Penicillin Antibiotics........................................................ 34 n Cephem Antibiotics......................................................... 34 n β-lactamase Inhibitors.................................................... 35 n Carbapenem Antibiotics................................................. 35 n Chloramphenicol Antibiotics.......................................... 36 n Aminoglycoside Antibiotics............................................ 36 n Macrolide Antibiotics....................................................... 36 n Tetracycline Antibiotics................................................... 37 n Other Antibiotics.............................................................. 37 14. Antimicrobial and Antiprotozoal Agents n Azole Antimicrobial Agents............................................ 38 n Allylamine Antifungal Agents......................................... 38 n New Quinolone Antimicrobial Agents.......................... 38 n Benzylamine Antimicrobial Agents............................... 39 n Polyene Antifungal Agents. . ........................................... 39 n Antiparasitic Agents........................................................ 39 15. Antitumor Agents n Alkylating Agents............................................................. 40 n Antitumor Antibiotics....................................................... 40 n Plant Antineoplastic Agents........................................... 41 n Antimetabolites................................................................ 41 n Hormone Preparations................................................... 42 n Other Antitumor Agents.................................................. 43 16. Antiviral Agents n Anti-HIV Agents............................................................... 43 n Anti-Herpesvirus Agents.. ............................................... 44 n Other Viral Agents........................................................... 44 17. Immune-Suppressive Agents n Specific Immunosuppressive Agents. . ......................... 45 n Cytotoxic Agents. . ............................................................ 45 18. Vitamins (1) Water-soluble vitamins n Vitamin B1........................................................................ 46 n Vitamin B2........................................................................ 46 n Vitamin-Related Compounds........................................ 46 n Vitamin B5-Related Compounds.................................. 46 n Vitamin B6........................................................................ 47 n Vitamin B7........................................................................ 47 n Vitamin B12...................................................................... 47 n Derivatives of Vitamin B1.. ............................................. 48 n Vitamin C.......................................................................... 48 (2) Fat-soluble vitamins n Vitamin D2........................................................................ 48 n Vitamin D3........................................................................ 48 n Vitamin E. . ......................................................................... 48 n Vitamin K1......................................................................... 48 n Vitamin-Related Compounds........................................ 48 19. Contrast Agents n X-ray Contrast Agents.................................................... 49 n Fluorescent Dyes............................................................ 49 page Description 21 A Acarbose 9 p -Acetamidophenol 23 2-Acetamido-5-sulfonamido-1,3,4-thiadiazole 9 Acetaminophen 9 Acetanilide 16 N -Acetyl-L-cysteine 9 p -Acetophenetidine 9 Acetylsalicylic Acid 27 Acetylsalicylic Acid 24 Actarit 29 Actarit 40 Actinomycin D 44 Acyclovir 8 1-Adamantanamine Hydrochloride Adenosine 5'-Triphosphate Disodium Salt Trihydrate, Crystallized 11 Afloqualone 18 Aldioxa 23 Alendronate Sodium Salt Trihydrate 22 Allopurinol 31 Allylestrenol 16 Ambroxol Hydrochloride 36 Amikacin Sulfate 13 Aminophylline 16 Aminophylline 17 5-Aminosalicylic Acid 5 Amitriptyline Hydrochloride 13 Amlodipine 12 Amlodipine Besilate 5 Amoxapine 34 Amoxicillin Trihydrate 39 Amphotericin B 34 Ampicillin Sodium 28 Ampiroxicam 23 Anetholtrithion 9 Antipyrine 48 L (+)-Ascorbic Acid 44 9-β-D-Arabinofuranosyladenine 13 Atenolol 33 Atropine Sulfate Monohydrate 24 Auranofin 18 Azasetron Hydrochloride 43 3'-Azido-3'-deoxythymidine 11 B Baclofen 49 Barium Sulfate 30 Beclomethasone Dipropionate 11 Benazepril Hydrochloride 22 Benzbromarone 34 Benzylpenicillin Potassium 34 Benzylpenicillin Sodium Salt 19 Berberine Chloride 30 Betamethasone 30 Betamethasone Dipropionate 30 Betamethasone Sodium Phosphate 30 Betamethasone Valerate 33 (±)-Betaxolol Hydrochloride 20 Bezafibrate 42 Bicalutamide 47 (+)-Biotin 8 Biperiden Hydrochloride 19 Bismuth (III) Carbonate Basic 13 Bosentan Hydrate 28 Bromelain 16 Bromhexine Hydrochloride 3 Bromovalerylurea 21 Buformine Hydrochloride 7 Bupropion Hydrochloride 32 Buserelin Acetate 40 1,4-Butanediol Dimethanesulfonate 39 Butenafine Hydrochloride 48 C Calciferol 46 Calcium (+)-Pantothenate 19 Calcium Polycarbophil 12 Candesartan Cilexetil 11 Captopril 26 Carbazochrome Sodium Sulfonate Trihydrate 43 Carboplatin 16 S -(Carboxymethyl)-L-cysteine 41 Carmofur 34 Cefaclor Monohydrate 34 Cefalexin 8 Index Alphabetical Index page Description 34 C Cefazolin Sodium Salt 35 Cefcapene Pivoxil Hydrochloride Hydrate 35 Cefdinir 35 Cefpirome Sulfate 35 Cefteram Pivoxil 34 Cephalothin Sodium Salt 16 Chloperastine Hydrochloride 36 Chloramphenicol 31 Chlormadinone Acetate 42 Chlormadinone Acetate 39 Chloroquine Diphosphate 29 (+)-Chlorpheniramine Maleate 4 Chlorpromazine Hydrochloride 21 Chlorpropamide 48 Cholecalciferol 45 Ciclosporin A 35 Cilastatin Sodium Salt 26 Cilostazol 17 Cimetidine 20 Ciprofibrate 39 Ciprofloxacin Hydrochloride Monohydrate 43 Cisplatin 7 Citalopram Hydrobromide 29 Clemastine Fumarate 37 Clindamycin Hydrochloride 31 Clobetasol Propionate 5 Clomipramine Hydrochloride 26 Clopidogrel Sulfate 38 Clotrimazole 48 Cocarboxylase 22 Colchicine 47 Cyanocobalamin 45 Cyclophosphamide Monohydrate 16 L-Cysteine 16 L-Cysteine Ethyl Ester Hydrochloride 16 L (−)-Cysteine Methyl Ester Hydrochloride 8 Cytidine 5'-Diphosphocholine 41 Cytosine-1-β-D (+)-arabinofuranoside 40 D Dacarbazine 31 Danazol 10 Dantrolene Sodium 40 Daunorubicin Hydrochloride 5 Desipramine Hydrochloride 30 Dexamethasone 30 Dexamethasone Dipropionate 31 Dexamethasone Sodium Phosphate 10 Dibucaine Hydrochloride 27 Diclofenac Sodium 43 Didanosine 44 2',3'-Dideoxycytidine 9 Difenidol Hydrochloride 13 Digitoxin 14 Dihydroergotamine Mesylate 14 8 3 12 38 29 14 14 46 14 41 18 8 5 42 40 7 6 29 29 11 39 22 29 40 37 3,4-Dihydroxyphenethylamine Hydrochloride (Dopamine Chloride) 3-(3,4-Dihydroxyphenyl)-L-alanine 2,6-Diisopropylphenol Diltiazem Hydrochloride (E )-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl1-naphthylmethylamine Hydrochloride Diphenhydramine Hydrochloride Dipyridamole Disopyramide (±)-1,2-Dithiolane-3-valeric Acid Dobutamine Hydrochloride Docetaxel Domperidone Donepezil Hydrochloride Doxepin Hydrochloride (mixture of isomers) Doxifluridine Doxorubicin Hydrochloride Droxidopa Duloxetine Hydrochloride E Ebastine Emedastine Difumarate Enalapril Maleate Enoxacin 1.5-Hydrate Epalrestat Epinastine Hydrochloride Epirubicin Hydrochloride Erythromycin ● If no storage conditions are specified, store at room temperature. ● Bulk quote requests for some products are welcomed. Please contuct us. ● Listed products are intended for laboratory research use only, and not to be used for drug, food or human use. page Description 31 E β-Estradiol 31 Estradiol Valerate 42 Estramustine Phosphate Disodium Salt 9 o -Ethoxybenzamide 10 Ethyl p-Aminobenzoate (Benzocaine) 3 Etizolam 27 Etodolac 41 Etoposide 45 Everolimus 17 F Famotidine 20 Fenofibrate 15 Fenoterol Hydrobromide 45 FK506 48 25 38 49 31 41 6 42 20 7 46 37 48 24 26 44 42 36 21 21 21 22 22 24 24 28 18 32 17 28 4 25 25 23 30 30 30 47 31 8 29 27 40 43 35 5 27 22 49 23 12 43 18 38 3 18 38 36 38 27 29 44 17 33 43 39 G H I K L Flavin Adenine Dinucleotide Disodium Salt n-Hydrate Flavoxate Hydrochloride Fluconazole Fluorescein Fluorometholone 5-Fluorouracil (±)-Fluoxetine Hydrochloride Flutamide Fluvastatin Sodium Fluvoxamine Maleate Folic Acid Fosfomycin Sodium Fursultiamine Hydrochloride (mixture of isomers) Gabexate Mesilate Gabexate Mesilate Ganciclovir Gemcitabine Hydrochloride Gentamicin Sulfate Glibenclamide Gliclazide Glimepiride Glucagon Hydrochloride (Human) L (+)-Glutamine Glutathione (Reduced Form) Glutathione, Oxidized Form Glycyrrhizin Granisetron Hydrochloride Growth Hormone, Human, recombinant Guaiazulene Guaiazulene Haloperidol Heparin Sodium Hexamethylenetetramine Hydrochlorothiazide Hydrocortisone Hydrocortisone Acetate Hydrocortisone Succinate Hydroxocobalamin Acetate Hydroxyprogesterone Caproate Ibudilast Ibudilast Ibuprofen Ifosfamide Imatinib Mesylate Imipenem n-Hydrate Imipramine Hydrochloride Indomethacin Insulin Glargine, recombinant Iopamidol Ipriflavone Irbesartan Irinotecan Hydrochloride Trihydrate Irsogladine Maleate Isoconazole Nitrate Isoflurane Itopride Hydrochloride Itraconazole Kanamycin Sulfate Ketoconazole Ketoprofen Ketotifen Fumarate Lamivudine Lansoprazole Latanoprost Lentinan Levofloxacin Hemihydrate 1 Index Alphabetical Index page 4 10 10 36 11 7 39 19 12 27 16 18 6 8 31 42 28 8 42 35 21 45 15 23 9 47 42 18 13 39 14 6 38 14 21 6 14 37 6 21 40 45 29 26 32 38 31 22 36 12 14 46 12 40 12 12 17 38 39 4 12 17 20 34 43 27 10 10 15 41 46 15 7 43 44 24 7 4 9 33 3 8 2 Description L Levomepromazine Maleate Lidocaine Lidocaine Hydrochloride Monohydrate Lincomycin Hydrochloride Monohydrate Lisinopril Dihydrate Lithium Carbonate Lomefloxacin Hydrochloride Loperamide Hydrochloride Losartan Potassium Salt Loxoprofen Sodium Salt Dihydrate Lysozyme, from Egg White M Magnesium Oxide Maprotiline Hydrochloride Meclofenoxate Hydrochloride Medroxyprogesterone Acetate Medroxyprogesterone Acetate Meloxicam Memantine Hydrochloride 6-Mercaptopurine Monohydrate Meropenem Trihydrate Metformin Hydrochloride Methotrexate Methoxyphenamine Hydrochloride Methyclothiazide Methyl Salicylate Methylcobalamin Methyltestosterone Metoclopramide Metoprolol Tartrate (mixture of isomers) Metronidazole Mexiletine Hydrochloride Mianserin Hydrochloride Miconazole Nitrate Midodrine Hydrochloride Miglitol Milnacipran Hydrochloride Milrinone Minocycline Hydrochloride Mirtazapine Mitiglinide Calcium Dihydrate Mitomycin C Mizoribine Montelukast Sodium Salt N Nafamostat Mesylate Nafarelin Acetate n -Hydrate Nalidixic Acid Nandrolone Decanoate Nateglinide Neomycin Sulfate Nicardipine Hydrochloride Nicorandil Nicotinic Acid Nifedipine Nimustine Hydrochloride Nisoldipine Nitrendipine Nizatidine Norfloxacin O Ofloxacin Olanzapine Olmesartan Medoxomil Omeprazole γ-Oryzanol Oxacillin Sodium Monohydrate Oxaliplatin Oxaprozin Oxethazaine Oxybuprocaine Hydrochloride Ozagrel Sodium Salt P Paclitaxel D (+)-Panthenol Papaverine Hydrochloride Paroxetine Hydrochloride Pemetrexed Disodium Heptahydrate Penciclovir D (−)-Penicillamine Pergolide Mesylate Perospirone Hydrochloride Dihydrate Phenacetin (R )-(-)-Phenylephrine Hydrochloride Phenytoin Picrotoxin page 19 13 22 33 17 28 25 19 15 27 20 13 30 30 22 20 10 40 15 29 14 13 22 47 47 47 4 14 39 11 17 45 43 44 46 36 37 23 4 25 22 20 36 15 19 19 6 25 20 46 18 28 18 19 9 3 18 13 23 36 8 35 37 4 17 9 5 29 42 41 12 44 18 15 31 10 37 46 26 32 4 26 Description P Pilocarpine Hydrochloride Pindolol Pioglitazone Hydrochloride Pirenoxine Pirenzepine Dihydrochloride Monohydrate Piroxicam Plasminogen, from Human Plasma Polaprezinc Pranlukast Pranoprofen (mixture of isomers) Pravastatin Sodium Salt Prazosin Hydrochloride Prednisolone Prednisolone Succinate Probenecid Probucol Procaine Hydrochloride Procarbazine Hydrochloride Procaterol Hydrochloride Hemihydrate Promethazine Hydrochloride Propafenone Hydrochloride (±)-Propranolol Hydrochloride Protoporphyrinato Zinc Pyridoxal Hydrochloride Pyridoxal Phosphate Monohydrate Pyridoxine Hydrochloride Q Quetiapine Fumarate Quinidine Sulfate Dihydrate Quinine R Ramipril Ranitidine Hydrochloride Rapamycin (mixture of isomers) all-trans -Retinoic Acid Ribavirin Riboflavin Tetrabutyrate Ribostamycin Sulfate Rifampicin Risedronate Sodium Salt n -Hydrate Risperidone Ritodrine Hydrochloride (mixture of isomers) Rosiglitazone Rosuvastatin Calcium Salt Roxithromycin S Salbutamol Sulfate Sennoside A Sennoside B Sertraline Hydrochloride Sildenafil Citrate Simvastatin Sodium (+)-Pantothenate Sodium Alginate 80-120 Sodium Cromoglicate Sodium Hydrogen Carbonate Sodium Picosulfate n-Hydrate Sodium Salicylate Sodium Valproate Sofalcone Spironolactone Spironolactone Streptomycin Sulfate Strychnine Nitrate Sulbactam Sodium Salt Sulfamethoxazole (±)-Sulpiride (±)-Sulpiride Sulpyrine Monohydrate Sultopride Hydrochloride Suplatast Tosylate T Tamoxifen Citrate Tegafur Telmisartan Tenofovir Teprenone (mixture of isomers) Terbutaline Sulfate Testosterone Enanthate Tetracaine Hydrochloride Tetracycline Hydrochloride Thiamin Hydrochloride Thrombin, Type 2, Human Plasma Thyrotropin Releasing Hormone Tiapride Hydrochloride Ticlopidine Hydrochloride Active Pharmaceutical Ingredients -Catalog- page Description 37 T Tigecycline 33 Timolol Maleate 39 Tinidazole 11 Tizanidine Hydrochloride 48 (±)-α-Tocopherol Acetate 20 (±)-α-Tocopherol Nicotinate 5 Tofisopam 21 Tolbutamide 11 Tolperisone Hydrochloride 39 Tosufloxacin Tosylate Monohydrate 28 Tranilast 26 7 31 10 15 14 49 23 12 37 10 6 13 41 41 41 41 48 21 25 44 3 3 U V W Z trans-4-Aminomethyl-1-cyclohexanecarboxylic Acid (Tranexamic Acid) Trazodone Hydrochloride Triamcinolone Acetonide D-Tubocurarine Chloride Pentahydrate Tulobuterol (mixture of isomers) Ubiquinone-10 Uranine Ursodeoxycholic Acid Valsartan Vancomycin Hydrochloride Vecuronium Bromide Venlafaxine Hydrochloride Verapamil Hydrochloride Vinblastine Sulfate Vincristine Sulfate Vindesine Sulfate Vinorelbine Ditartrate Vitamin K1 Voglibose Warfarin Sodium Zanamivir Zonisamide Zopiclone Please visit the Wako Online Catalog: http://www.e-reagent.com 1. Agents Acting on Central Nervous System n Anesthetic Agents Product Name Wako Cat. No. Isoflurane 099-06571 for Biochemistry Pkg. Size 250mL Product Name 2,6-Diisopropylphenol CAS No. 26675-46-7 C3H2ClF5O=184.49 [Assay] 98.0+% (cGC) [Soluble in] Ethanol [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] This product is a compound that acts on the central nervous system to exert anesthetic effects. Wako Cat. No. 321-98212 329-98213 Pkg. Size 1 25g 250g CAS No. 2078-54-8 C12H18O=178.27 [Assay] 97.0+% [Intended Purpose (Potency)] This product is an isopropylphenol derivative. It acts on GABAA receptors to exert anesthetic effects. n Hypnotic Agents n Benzodiazepine Compounds Etizolam Product Name Wako Cat. No. 057-06811 for Biochemistry Pkg. Size 500mg Product Name Zopiclone for Pharmacology Research CAS No. 40054-69-1 C17H15ClN4S=342.85 [Assay] 98.0+% (Titration) [Soluble in] Ethanol [Intended Purpose (Potency)] Benzodiazepine derivative It exhibits central nervous system depressant action such as muscle relaxation, anticonvulsant activity and taming. This product is short-acting. n Other Hypnotic Agents Product Name Bromovalerylurea Wako Cat. No. 020-17192 for Pharmacology Research Wako Cat. No. 266-02081 262-02083 Pkg. Size 10mg 50mg CAS No. 43200-80-2 C17H17ClN6O3=388.81 [Assay] 98.0+% (HPLC) [Soluble in] DMSO [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] Non-benzodiazepine cyclopyrrolone derivative. It is believed to bind to benzodiazepine ω1 receptors and ultimately activate GABA receptors. Pkg. Size 25g CAS No. 496-67-3 C6H11BrN2O2=223.07 [Assay] 98.0+% (HPLC), 98.0+% (Titration) (after drying) [Soluble in] Ethanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] Bromovalerylurea in vivo suppresses excitation of the brain and exhibits sedation and hypnotic effect by releasing Br- in blood and substituting with Cl- in the body. n Antiepileptic Agents Product Name Phenytoin Wako Special Grade Wako Cat. No. 166-12082 168-12081 Pkg. Size 25g 100g Product Name Sodium Valproate Wako 1st Grade CAS No. 57-41-0 C15H12N2O2=252.27 [Assay] 99.0+% (Titration) [Soluble in] Sodium hydroxide solution [Intended Purpose (Potency)] This product reduces sodium permeability. Zonisamide for Pharmacology Research 265-01951 Wako Cat. No. 197-09722 Pkg. Size 25g CAS No. 1069-66-5 C8H15NaO2=166.19 [Assay] 98.0+% (Titration) [Soluble in] Water [Intended Purpose (Potency)] This product inhibits GABA transaminase. 100mg CAS No. 68291-97-4 C8H8N2O3S=212.23 [Assay] 98.0+% (HPLC) [Soluble in] Acetone [Intended Purpose (Potency)] The basic structure is a benzisoxazole structure that contains a sulfamoyl group. It reduces calcium permeability. ● If no storage conditions are specified, store at room temperature. ● Bulk quote requests for some products are welcomed. Please contuct us. ● Listed products are intended for laboratory research use only, and not to be used for drug, food or human use. 3 n Antipsychotic Agents n Phenothiazine Compounds Product Name Chlorpromazine Hydrochloride 1 for Biochemistry Wako Cat. No. 033-10581 Pkg. Size 10g Product Name Levomepromazine Maleate for Biochemistry Product Name Haloperidol Wako Special Grade Wako Cat. No. 084-04261 080-04263 082-04262 128-06151 124-06153 Pkg. Size 10mg 50mg CAS No. 7104-38-3 C19H24N2OS · C4H4O4=444.54 [Assay] 90.0+% (HPLC) [Soluble in] Methanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] Phenothiazine compound. Dopamine D2 receptor antagonist. CAS No. 69-09-0 C17H19ClN2S · HCl=355.33 [Assay] 99.0+% (Titration) [Soluble in] Water [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] Phenothiazine compound. Dopamine D2 receptor antagonist. n Butyrophenone Compound Wako Cat. No. Pkg. Size 1g 5g 25g CAS No. 52-86-8 C21H23ClFNO2=375.86 [Assay] 98.0+% (Titration) [Soluble in] Chloroform [Intended Purpose (Potency)] Butyrophenone antipsychotic. Haloperidol works by blocking a variety of receptors in the brain, particularly dopamine D2 receptors. n Benzoisoxazol Derivatives Product Name Risperidone for Pharmacology Research Wako Cat. No. 188-02311 184-02313 Pkg. Size 50mg 250mg Product Name Perospirone Hydrochloride Dihydrate for Pharmacology Research CAS No. 106266-06-2 C23H27FN4O2=410.48 [Soluble in] Methanol [Intended Purpose (Potency)] Benzoisoxazol derivative. Exhibit antagonism of dopamine D2 receptors and serotonin 5-HT2 receptors. n Multi-Acting Receptor-Targeted Antipsychotics (MARTA) Product Name Olanzapine for Pharmacology Research Wako Cat. No. 150-03071 156-03073 Pkg. Size 50mg 500mg Product Name (±)-Sulpiride for Biochemistry Wako Cat. No. 190-12061 198-12062 196-12063 Pkg. Size 1g 25g 100g CAS No. 15676-16-1 C15H23N3O4S=341.43 [Assay] 98.0+% (Titration) [Soluble in] Dilute acetic acid [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] Benzamide derivative While its pharmacological effect is specific blocking of dopamine D2 receptor (referred to as D2, hereinafter), peripheral D2 blocking occurs more potently than the central D2 blocking due to poor distribution in the brain. 4 Active Pharmaceutical Ingredients -Catalog- 167-25241 163-25243 Pkg. Size 5mg 50mg CAS No. 192052-81-6 C23H30N4O2S · HCl · 2H2O=499.07 [Assay] 98.0+% (HPLC) [Soluble in] Water [Intended Purpose (Potency)] Benzoisoxazol derivative. Exhibit antagonism of dopamine D2 receptors and serotonin 5-HT2 receptors. Product Name Quetiapine Fumarate for Pharmacology Research CAS No. 132539-06-1 C17H20N4S=312.43 [Assay] 98.0+% (HPLC) [Soluble in] Acetonitrile [Intended Purpose (Potency)] This product exhibits antagonism to multiple neurotransmitter receptors such as dopamine and serotonin receptors. n Benzamide Derivatives Wako Cat. No. Wako Cat. No. 172-00691 178-00693 Pkg. Size 1g 10g CAS No. 111974-72-2 (C21H25N3O2S) 2 · C4H4O4=883.09 [Assay] 98.0+% (HPLC) [Soluble in] N,N- Dimethylformamide [Intended Purpose (Potency)] Dibenzothiazepine compound It inhibits dopamine D2 receptor and serotonin 5HT2 receptor. And it shows higher affinity to serotonin 5HT2 receptor than dopamine D2 receptor. It shows affinity to a number of receptors other than dopamine D2 and serotonin 5HT2. Product Name Tiapride Hydrochloride for Pharmacology Research Wako Cat. No. Pkg. Size 201-19681 10mg 207-19683 100mg CAS No. 51012-33-0 C15H24N2O4S · HCl=364.89 [Assay] 98.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] Benzamide derivative It binds to the brain dopamine D2 receptor and facilitates the release of acetylcholine. Please visit the Wako Online Catalog: http://www.e-reagent.com Product Name Sultopride Hydrochloride for Biochemistry Wako Cat. No. Pkg. Size 190-17061 100mg 196-17063 500mg CAS No. 23694-17-9 C17H26N2O4S · HCl=390.93 [Assay] 90.0 - 105.0% (Titration) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] Benzamide derivative Selective antagonist of dopamine D2 receptors 1 n Anti-Anxiety Agent Product Name Tofisopam for Pharmacology Research Wako Cat. No. 201-19201 207-19203 Pkg. Size 50mg 500mg CAS No. 22345-47-7 C22H26N2O4=382.45 [Assay] 98.0+% (HPLC) [Soluble in] Ethanol [Intended Purpose (Potency)] Benzodiazepine derivative It acts on GABA receptors to exhibit central nervous system depressant action. It is considered to be short-acting. n Antidepressant Agents n Tricyclic Antidepressant Agents Product Name Imipramine Hydrochloride for Pharmacology Research Wako Cat. No. Pkg. Size 097-06491 5g 093-06493 50g Product Name Doxepin Hydrochloride (mixture of isomers) for Pharmacology Research CAS No. 113-52-0 C19H24N2 · HCl=316.87 [Assay] 98.0+% (HPLC) [Soluble in] Water [Intended Purpose (Potency)] Tricyclic antidepressant. It inhibits reuptake of noradrenaline and serotonin into nerve endings. Clomipramine Hydrochloride for Pharmacology Research 036-21941 1g 032-21943 5g for Pharmacology Research 015-23631 1g 011-23633 5g Pkg. Size 043-32001 1g 049-32003 5g CAS No. 1229-29-4 C19H21NO · HCl=315.84 [Assay] 98.0+% (HPLC) (mixture of isomers) [Soluble in] Water [Intended Purpose (Potency)] Tricyclic antidepressant It inhibits uptake of serotonin (5-HT) and noradrenaline in nerve terminals in the brain. Desipramine Hydrochloride for Biochemistry CAS No. 17321-77-6 C19H23ClN2 · HCl=351.31 [Assay] 98.0+% (volumetric analysis), 98.0+% (HPLC) [Soluble in] Water [Intended Purpose (Potency)] Tricyclic antidepressant It inhibits uptakes of serotonin (5-HT) and noradrenaline to nerve terminals in the brain. Clomipramine is a chlorine derivative of imipramine and it exhibits more potent inhibitory activity against serotonin uptake than that against noradrenaline uptake compared to other tricyclic antidepressants such as imipramine. Amoxapine Wako Cat. No. 044-23121 1g 040-23123 5g CAS No. 58-28-6 C18H22N2 · HCl=302.85 [Assay] 99.0+% (volumetric analysis) 99+% (TLC) [Soluble in] Water [Intended Purpose (Potency)] Tricyclic antidepressant It inhibits uptake of serotonin (5-HT) and noradrenaline in nerve terminals in the brain. Amitriptyline Hydrochloride for Biochemistry CAS No. 14028-44-5 C17H16ClN3O=313.78 [Assay] 98.0+% (HPLC) [Soluble in] Methanol [Intended Purpose (Potency)] Tricyclic antidepressant It inhibits uptake of serotonin (5-HT) and noradrenaline in nerve terminals in the brain. ● If no storage conditions are specified, store at room temperature. ● Bulk quote requests for some products are welcomed. Please contuct us. ● Listed products are intended for laboratory research use only, and not to be used for drug, food or human use. 013-12882 25g CAS No. 549-18-8 C20H23N · HCl=313.87 [Assay] 99.0+ % (Titration) [Soluble in] water, chloroform and ethanol [Intended Purpose (Potency)] Tricyclic antidepressant substance, anxiolytic substance. It inhibits reuptake of noradrenaline and serotonin in the brain and exerts an antidepressant action. 5 n Tetracyclic Antidepressants Product Name Maprotiline Hydrochloride for Pharmacology Research Wako Cat. No. 139-17091 135-17093 Pkg. Size 1g 5g Product Name Mirtazapine for Pharmacology Research CAS No. 10347-81-6 C20H23N · HCl=313.86 [Assay] 98.0+% (HPLC) [Soluble in] Methanol [Intended Purpose (Potency)] Tetracyclic antidepressant This product increases noradrenaline concentrations by inhibiting the reuptake of noradrenaline into the nerve terminals. 1 Mianserin Hydrochloride for Pharmacology Research 132-16861 50mg 138-16863 500mg Product Name Milnacipran Hydrochloride for Pharmacology Research Wako Cat. No. 133-17011 139-17013 Pkg. Size 25mg 100mg Product Name Venlafaxine Hydrochloride for Pharmacology Research CAS No. 101152-94-7 C15H22N2O · HCl=282.81 [Assay] 98.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] Serotonin-noradrenaline reuptake inhibitor (SNRI) SNRI selectively binds to the serotonin and norepinephrine reuptake sites in the nerve terminal, thereby inhibiting the reuptake of serotonin and norepinephrine resulting in greater concentrations of both neurotransmitters in the brain. Duloxetine Hydrochloride for Pharmacology Research 041-32041 10mg 047-32043 100mg 134-16821 130-16823 Pkg. Size 10mg 50mg CAS No. 85650-52-8 C17H19N3=265.35 [Assay] 98.0+% (HPLC) [Soluble in] Ethanol [Intended Purpose (Potency)] Tetracyclic antidepressant. Naradrenergic and specific serotonergic antidepressant (NaSSA) NaSSA acts as antagonist on the presynaptic α2 adrenergic autoreceptors and heteroreceptors to increase the release of noradrenaline and serotonin in the brain, therby enhancing neurotransmission. CAS No. 21535-47-7 C18H20N2 · HCl=300.83 [Soluble in] Water [Intended Purpose (Potency)] Tetracyclic antidepressant This product is an antagonist at the presynaptic α2 adrenergic autoreceptors, therby promoting the release of noradrenaline into synaptic cleft. n Serotonin-Noradrenaline Reuptake Inhibitors (SNRI) Wako Cat. No. Wako Cat. No. 227-01951 Pkg. Size 500mg CAS No. 99300-78-4 C17H27NO2 · HCl=313.86 [Assay] 98.0+% (HPLC) [Soluble in] Water [Intended Purpose (Potency)] Serotonin-noradrenaline reuptake inhibitor (SNRI) SNRI selectively binds to the serotonin and norepinephrine reuptake sites in the nerve terminal, thereby inhibiting the reuptake of serotonin and norepinephrine resulting in greater concentrations of both neurotransmitters in the brain. CAS No. 136434-34-9 C18H19NOS · HCl=333.88 [Assay] 98.0+% (HPLC) [Soluble in] Methanol [Intended Purpose (Potency)] Serotonin-noradrenaline reuptake inhibitor (SNRI) SNRI selectively binds to the serotonin and norepinephrine reuptake sites in the nerve terminal, thereby inhibiting the reuptake of serotonin and norepinephrine resulting in greater concentrations of both neurotransmitters in the brain. n Serotonin-Selective Reuptake Inhibitors (SSRI) Product Name (±)-Fluoxetine Hydrochloride for Pharmacology Research Wako Cat. No. Pkg. Size 068-04321 10mg 064-04323 50mg 068-04326 1g CAS No. 56296-78-7 C17H18F3NO · HCl=345.79 [Assay] 98.0+ % (HPLC) [Soluble in] methanol, ethanol, acetonitrile, chloroform, acetone [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] Selective serotonin reuptake inhibitor (SSRI). It inhibits serotonin reuptake and consequently elevates serotonin concentration in synaptic gaps exhibiting antidepressive effect. 6 Active Pharmaceutical Ingredients -Catalog- Product Name Sertraline Hydrochloride for Pharmacology Research Wako Cat. No. 193-16191 199-16193 Pkg. Size 100mg 1g CAS No. 79559-97-0 C17H17Cl2N · HCl=342.69 [Assay] 98.0+% (HPLC) [Soluble in] Methanol [Intended Purpose (Potency)] SSRIs are believed to increase the extracellular levels of the neurotransmitter serotonin by inhibiting the reuptake into the presynaptic cells in the brain. Please visit the Wako Online Catalog: http://www.e-reagent.com Product Name Citalopram Hydrobromide for Pharmacology Research Wako Cat. No. 031-22231 037-22233 Pkg. Size 25mg 100mg Product Name Fluvoxamine Maleate for Pharmacology Research for Pharmacology Research 168-24431 065-05171 061-05173 Pkg. Size 5g 100g CAS No. 61718-82-9 C15H21F3N2O2 · C4H4O4=434.41 [Assay] 98.0+% (HPLC) [Soluble in] Ethanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] SSRIs are believed to increase the extracellular levels of the neurotransmitter serotonin by inhibiting the reuptake into the presynaptic cells in the brain. CAS No. 59729-32-7 C20H21FN2O · HBr=405.30 [Assay] 98.0+% (HPLC) [Soluble in] Methanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] SSRIs are believed to increase the extracellular levels of the neurotransmitter serotonin by inhibiting the reuptake into the presynaptic cells in the brain. Paroxetine Hydrochloride Wako Cat. No. 100mg CAS No. 78246-49-8 C19H20FNO3 · HCl=365.83 [Assay] 98.0+% (HPLC) [Soluble in] Water [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] SSRIs are believed to increase the extracellular levels of the neurotransmitter serotonin by inhibiting the reuptake into the presynaptic cells in the brain. n Other Antidepressants Product Name Trazodone Hydrochloride for Biochemistry Wako Cat. No. 209-14964 205-14961 Pkg. Size 500mg 5g Product Name Bupropion Hydrochloride for Pharmacology Research CAS No. 25332-39-2 C19H22ClN5O · HCl=408.32 [Assay] 98.0+% (HPLC) [Soluble in] Ethanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is a triazolopyridine antidepressant. It inhibits the uptake of serotonin. Wako Cat. No. 028-17311 024-17313 Pkg. Size 100mg 1g CAS No. 31677-93-7 C13H18ClNO · HCl=276.20 [Assay] 98.0+% (HPLC) [Soluble in] Water [Intended Purpose (Potency)] This product is a noradrenaline dopamine reuptake inhibitor (NDRI). It inhibits the reuptake of noradrenaline and dopamine. n Antimanic Agent Product Name Lithium Carbonate Wako Special Grade Li2CO3 Wako Cat. No. 122-01132 124-01131 126-01135 Pkg. Size 25g 100g 250g CAS No. 554-13-2 Li2CO3=73.89 [Assay] 99.0+% (Titration) (after drying) [Soluble in] Dilute hydrochloric acid [Intended Purpose (Potency)] It is believed to act on multiple neurotransmitters and receptors in the central nervous system. n Antiparkinsonism Agents Product Name Droxidopa for Biochemistry Wako Cat. No. 041-32801 047-32803 Pkg. Size 10mg 50mg Product Name Pergolide Mesylate for Biochemistry CAS No. 23651-95-8 C9H11NO5=213.19 [Assay] 90.0+% (HPLC) [Soluble in] Dilute hydrochloric acid [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] Droxidopa is converted to ℓ-noradrenaline by aromatic L-amino acid decarboxylase that is widely present in the living body. Converted noradrenaline exhibits central and peripheral pharmacological actions. ● If no storage conditions are specified, store at room temperature. ● Bulk quote requests for some products are welcomed. Please contuct us. ● Listed products are intended for laboratory research use only, and not to be used for drug, food or human use. Wako Cat. No. 166-25691 162-25693 Pkg. Size 100mg 250mg CAS No. 66104-23-2 C19H26N2S · CH4O3S=410.59 [Assay] 90.0+% (HPLC) [Soluble in] DMSO [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] Pergolide mesylate acts directly on nigrostriatal dopamine receptors, exerting dopaminergic effects. The action mechanism of pergolide mesylate is direct stimulation of striatal dopamine D1/D2 receptors. 7 1 Product Name Biperiden Hydrochloride for Biochemistry Wako Cat. No. 022-14771 028-14773 Pkg. Size 500mg 5g Product Name 1-Adamantanamine Hydrochloride Wako Special Grade CAS No. 1235-82-1 C21H29NO · HCl=347.92 [Assay] 98.0+% (Titration) [Soluble in] Formic acid [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] An antiparkinsonism drug. It exhibits central nervous anticholinergic effect. 1 3-(3,4-Dihydroxyphenyl)-L-alanine Wako 1st Grade 047-30561 043-30563 041-30564 045-30562 Wako Cat. No. 017-08051 Pkg. Size 10g CAS No. 665-66-7 C10H15NH2 · HCl=187.71 [Assay] 98.0+% (Titration) [Soluble in] Water [Intended Purpose (Potency)] This product is a dopaminergic compound. It promotes dopamine release. 100mg 1g 5g 25g CAS No. 59-92-7 C9H11NO4=197.19 [Assay] 98.0+% (Titration) (after drying) [Soluble in] Dilute hydrochloric acid [Intended Purpose (Potency)] L-DOPA Dopamine precursor n Anti-Alzheimer's Disease Agents Product Name Memantine Hydrochloride for Cellbiology Wako Cat. No. 132-16981 138-16983 Pkg. Size 25mg 100mg Product Name Donepezil Hydrochloride for Biochemistry CAS No. 41100-52-1 C12H21N · HCl=215.76 [Soluble in] Water [Intended Purpose (Potency)] This is a glutaminergic NMDA receptor antagonist and stimulates dopamine release by binding to the ion channel site. It is used in researches on Parkinson's disease, spasms, Alzheimer's disease, etc. Wako Cat. No. 045-32321 041-32323 Pkg. Size 50mg 250mg CAS No. 120011-70-3 C24H29NO3 · HCl=415.95 [Assay] 90.0+% (HPLC) [Storage condition] Keep at 2-10℃. [Soluble in] Water [Intended Purpose (Potency)] An acetylcholinesterase inhibitor. It is a reversible acetylcholinesterase (AChE) inhibitor. Donepezil-induced downregulation of AChE leads to increased levels of acetylcholine in the brain, which in turn stimulates cholinergic nerve system in the brain. n Central Nervous System Stimulants Product Name Strychnine Nitrate Wako Special Grade Wako Cat. No. 195-11151 193-11152 Pkg. Size 5g 25g Product Name Picrotoxin Wako 1st Grade CAS No. 66-32-0 C21H22N2O2 · HNO3=397.43 [Assay] 98.0+% (Titration) [Soluble in] Water [Intended Purpose (Potency)] This product inhibits postsynaptic inhibition. Wako Cat. No. 168-17961 164-17963 Pkg. Size 1g 5g CAS No. 124-87-8 C30H34O13=602.58 [Assay] 97.0+% (HPLC) [Soluble in] Ethanol [Intended Purpose (Potency)] This product is an equimolecular compound composed of one molecule of both picrotoxinin and picrotin. It acts on the picrotoxin-binding sites to inhibit presynaptic inhibition. n Brain Metabolic Stimulants Product Name Cytidine 5'-Diphosphocholine for Biochemistry Wako Cat. No. 032-14071 038-14073 036-14074 Pkg. Size 100mg 500mg 1g Product Name Meclofenoxate Hydrochloride for Biochemistry for Biochemistry 018-16911 1g 014-16913 5g CAS No. 51963-61-2 C10H14N5Na2O13P3 · 3H2O=605.19 [Assay] 97.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] It is involved in many biochemical reactions as a representative energy transmitter. 8 Active Pharmaceutical Ingredients -Catalog- 130-17521 138-17522 Pkg. Size 5g 25g CAS No. 3685-84-5 C12H16ClNO3 · HCl=294.17 [Assay] 90.0+% (Titration) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] It is a Central Nervous System stimulant that aids cerebral metabolism and functions by aiding glucose transport through the blood-brain barrier, promoting glucose metabolism in the brain and enhancing cerebral blood flow. CAS No. 987-78-0 C14H26N4O11P2=488.32 [Assay] 98.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is an intermediate produced during steps of phosphatidylcholine biosynthesis. It acts as a cerebral metabolic activator. Adenosine 5'-Triphosphate Disodium Salt Trihydrate, Crystallized Wako Cat. No. Ibudilast for Pharmacology Research 096-06101 10mg 092-06103 50mg CAS No. 50847-11-5 C14H18N2O=230.31 [Assay] 98.0+% (HPLC) [Soluble in] Ethanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product inhibits release of leukotrienes C4 and B4 and exhibits antagonistic activity against leukotrienes and PAF. It also affect prostaglandin I2. It is used as therapeutic medicine for bronchial asthma. Please visit the Wako Online Catalog: http://www.e-reagent.com Product Name Difenidol Hydrochloride for Biochemistry Wako Cat. No. 049-21731 Pkg. Size 5g CAS No. 3254-89-5 C21H27NO · HCl=345.91 [Assay] 98.5+% (Titration) [Soluble in] Ethanol [Intended Purpose (Potency)] This product increases cerebral blood flow. 1 n Antipyretic Analgesics n Salicylate Compounds Product Name Acetylsalicylic Acid Wako Special Grade Wako Cat. No. 015-10262 017-10261 019-10265 Pkg. Size 25g 100g 500g Product Name Methyl Salicylate Wako 1st Grade JIS Special Grade 191-03142 25g 195-03145 500g o -Ethoxybenzamide Wako Special Grade Product Name p -Acetophenetidine (Phenacetin) Wako 1st Grade Wako Cat. No. 019-00412 013-00415 Pkg. Size 25g 500g Product Name Acetanilide Wako Special Grade CAS No. 62-44-2 C10H13NO2=179.22 [Assay] 98.0+% (HPLC) [Soluble in] Ethanol [Intended Purpose (Potency)] An aniline compound It is metabolized to acetaminophen in the body and exerts the effect. p -Acetamidophenol (Acetaminophen) Wako 1st Grade 015-13942 25mL 139-03066 500mL 057-04932 25g 051-04935 500g CAS No. 938-73-8 C9H11NO2=165.19 [Assay] 98.0+% (HPLC) [Soluble in] Ethanol, Acetone [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] Prostaglandin biosynthesis inhibitor CAS No. 54-21-7 C7H5NaO3=160.10 [Assay] 99.5+% (Titration) [Soluble in] Water, Ethanol [Intended Purpose (Potency)] Prostaglandin biosynthesis inhibitor This product is a sodium compound of salicylic acid. n Aniline Compounds Pkg. Size 135-03063 CAS No. 119-36-8 C8H8O3=152.15 [Assay] 98.0+% (cGC) [Soluble in] Potassium hydroxide [Intended Purpose (Potency)] Prostaglandin biosynthesis inhibitor This product is an adduct produced by the addition of a methyl group to salicylic acid. CAS No. 50-78-2 C9H8O4=180.16 [Assay] 99.5+% (Titration) (after drying) [Soluble in] Ethanol [Intended Purpose (Potency)] Prostaglandin biosynthesis inhibitor Sodium Salicylate Wako Cat. No. Wako Cat. No. 017-00212 011-00215 Pkg. Size 25g 500g CAS No. 103-84-4 C8H9NO=135.16 [Assay] 99.0+% (Titration) [Soluble in] Ethanol [Intended Purpose (Potency)] An aniline compound This product inhibits cyclooxygenase (COX) activity and prostaglandin biosynthesis. 25g CAS No. 103-90-2 C8H9NO2=151.16 [Assay] 97.0+% (HPLC) [Soluble in] Ethanol [Intended Purpose (Potency)] An aniline compound This product inhibits cyclooxygenase (COX) activity and prostaglandin biosynthesis. n Pyrazolone Compounds Product Name Sulpyrine Monohydrate Wako Special Grade Wako Cat. No. 191-08902 Pkg. Size 25g Product Name Antipyrine for Biochemistry CAS No. 5907-38-0 C13H16N3NaO4S · H2O=351.35 [Assay] 98.0 - 102.0% (Titration) [Soluble in] Water [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] A pyrazolone compound Prostaglandin biosynthesis inhibitor ● If no storage conditions are specified, store at room temperature. ● Bulk quote requests for some products are welcomed. Please contuct us. ● Listed products are intended for laboratory research use only, and not to be used for drug, food or human use. Wako Cat. No. 018-11112 010-11111 Pkg. Size 25g 100g CAS No. 60-80-0 C11H12N2O=188.23 [Assay] 99.0+% (Titration) (after drying) [Soluble in] Water [Intended Purpose (Potency)] A pyrazolone compound Prostaglandin biosynthesis inhibitor 9 2. Agents Acting on Somatic Nervous System n Local Anesthetics Product Name Wako Cat. No. Lidocaine for Pharmacology Research 123-05001 121-05002 Pkg. Size 5g 25g Product Name Oxybuprocaine Hydrochloride for Pharmacology Research CAS No. 137-58-6 C14H22N2O=234.34 [Assay] 99.0+% (Titration) [Soluble in] Ethanol [Intended Purpose (Potency)] This product reduces sodium permeability. 2 Lidocaine Hydrochloride Monohydrate for Pharmacology Research 125-05681 123-05682 121-05683 5g 25g 100g 049-20011 1g 045-20013 5g Wako Cat. No. 158-02891 154-02893 Pkg. Size 1g 5g CAS No. 5987-82-6 C17H28N2O3 · HCl=344.88 [Assay] 98.0+% (Titration) [Soluble in] Water [Intended Purpose (Potency)] This product is procaine containing a butoxy group replaced at the para position. The efficacy of the product is believed to be equivalent to or slightly more powerful than that of dibucaine. It acts as a sodium ion channel blocker in unmyelinated nerve fibers and fine myelinated nerve fibers within the primary sensory nerves. Tetracaine Hydrochloride for Biochemistry CAS No. 6108-05-0 C14H22N2O · HCl · H2O=288.81 [Assay] 97.0+% (HPLC) [Soluble in] Ethanol [Intended Purpose (Potency)] This product reduces sodium permeability. Hydrochloride is more quick-acting than lidocaine. 207-09031 5g 205-09032 25g CAS No. 136-47-0 C15H24N2O2 · HCl=300.83 [Assay] 98.5+% (Titration) (after drying) [Soluble in] Water [Intended Purpose (Potency)] This product reduces sodium permeability. · H2O · HCl Dibucaine Hydrochloride for Biochemistry Ethyl p -Aminobenzoate (Benzocaine) Wako Special Grade CAS No. 61-12-1 C20H29N3O2 · HCl=379.92 [Assay] 98.0+% (Titration) (after drying) [Soluble in] Water [Intended Purpose (Potency)] This product binds to the specific binding sites in the neuronal sodium channel to block ion influx into cells and inhibit the generation of action potential, thereby exerting local anesthetic effects. Procaine Hydrochloride for Biochemistry 167-15111 50g 057-03832 051-03835 057-03837 25g 500g 10kg 153-02721 5g 151-02722 25g CAS No. 94-09-7 C9H11NO2=165.19 [Assay] 98.0+% (Titration) [Soluble in] Ethanol [Intended Purpose (Potency)] This product acts as a surface anesthetic. Oxethazaine for Pharmacology Research CAS No. 51-05-8 C13H20N2O2 · HCl=272.77 [Assay] 99.0+% (Titration) [Soluble in] Water [Intended Purpose (Potency)] This product reduces sodium permeability. CAS No. 126-27-2 C28H41N3O3=467.64 [Assay] 98.0+% [Soluble in] Ethanol [Intended Purpose (Potency)] This product inhibits gastrin secretion. n Peripheral Muscle Relaxants Product Name D-Tubocurarine Chloride Pentahydrate Wako 1st Grade Wako Cat. No. 201-13581 207-13583 Pkg. Size 100mg 1g C37H41ClN2O6 · HCl · 5H2O=771.72 [Assay] 97.0 - 103.0% (Titration) (calculated on the anhydrous basis) [Soluble in] Ethanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product blocks acetylcholine receptors at the neuromuscular junctions. Vecuronium Bromide for Pharmacology Research 223-01811 10mg 229-01813 50mg Product Name Dantrolene Sodium Wako Cat. No. 321-36111 327-36113 Pkg. Size 1g 5g CAS No. 14663-23-1 C14H9N4NaO5=336.23 [Assay] 97.0+% [Intended Purpose (Potency)] This product inhibits calcium release in the sarcoplasmic reticulum. CAS No. 50700-72-6 C34H57BrN2O4=637.73 [Assay] 98.0+% (HPLC) [Soluble in] Dilute hydrochloric acid [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] This product blocks excitatory transmission from nerves to muscles via acetylcholine at the neuromuscular junctions and acts as a non-depolarizing neuromuscular blocking agent as with D-Tubocurarine. 10 Active Pharmaceutical Ingredients -Catalog- Please visit the Wako Online Catalog: http://www.e-reagent.com n Central Muscle Relaxants Product Name Tizanidine Hydrochloride for Pharmacology Research Wako Cat. No. 208-19691 204-19693 Pkg. Size 10mg 50mg Product Name Afloqualone for Biochemistry CAS No. 64461-82-1 C9H8ClN5S · HCl=290.17 [Assay] 98.0+% (HPLC) [Soluble in] Methanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product inhibits multiple synapses. Tolperisone Hydrochloride for Biochemistry 205-10821 5g 203-10822 25g Wako Cat. No. 014-24681 010-24683 Pkg. Size 50mg 500mg CAS No. 56287-74-2 C16H14FN3O=283.30 [Assay] 90.0+% (HPLC) [Soluble in] Acetonitrile [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] This product inhibits monosynaptic and polysynaptic reflexes. Baclofen for Biochemistry CAS No. 3644-61-9 C16H23NO · HCl=281.83 [Assay] 98.5+% (Titration) [Soluble in] Water [Intended Purpose (Potency)] This product inhibits monosynaptic and polysynaptic reflexes. 2 3 029-10261 1g CAS No. 1134-47-0 C10H12ClNO2=213.66 [Assay] 99+% (TLC) 98.0+% (volumetric analysis) [Soluble in] Ethanol-acetic acid [Intended Purpose (Potency)] This product is a GABA derivative and inhibits monosynaptic and polysynaptic reflexes in the spinal cord. 3. Agents Acting on Cardiovascular System n Antihypertensives n Angiotensin-Converting Enzyme (ACE-1) Inhibitors Product Name Captopril for Pharmacology Research Wako Cat. No. 039-20951 035-20953 037-20952 Pkg. Size 1g 5g 25g Product Name Ramipril for Biochemistry for Biochemistry 128-04711 1g 124-04713 5g Enalapril Maleate for Biochemistry CAS No. 76547-98-3 C21H31N3O5 · 2H2O=441.52 [Assay] 98.0+% (HPLC) [Soluble in] Water [Intended Purpose (Potency)] This product is an angiotensin-converting enzyme (ACE-1) inhibitor. It inhibits angiotensin-converting enzymes and the production of angiotensin II . Benazepril Hydrochloride for Biochemistry 024-14091 1g 020-14093 5g Pkg. Size 187-02761 25mg 183-02763 100mg CAS No. 87333-19-5 C23H32N2O5=416.51 [Assay] 90.0+% (HPLC) [Soluble in] DMSO [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is an angiotensin-converting enzyme (ACE-1) inhibitor. It inhibits angiotensin-converting enzymes and the production of angiotensin II . CAS No. 62571-86-2 C9H15NO3S=217.29 [Assay] 96.0+% (Titration) [Soluble in] Ethanol [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] This product is an angiotensin-converting enzyme (ACE-1) inhibitor. It inhibits angiotensin-converting enzymes and the production of angiotensin II . Lisinopril Dihydrate Wako Cat. No. 051-06711 1g 057-06713 5g CAS No. 76095-16-4 C20H28N2O5 · C4H4O4=492.52 [Assay] 98.0+% (HPLC) [Soluble in] Methanol [Intended Purpose (Potency)] This product is an angiotensin-converting enzyme (ACE-1) inhibitor. It inhibits angiotensin-converting enzymes and the production of angiotensin II . CAS No. 86541-74-4 C24H28N2O5 · HCl=460.95 [Assay] 97.0+% (HPLC) [Soluble in] Ethanol [Intended Purpose (Potency)] This product is an angiotensin-converting enzyme (ACE-1) inhibitor. It inhibits angiotensin-converting enzymes and the production of angiotensin II . ● If no storage conditions are specified, store at room temperature. ● Bulk quote requests for some products are welcomed. Please contuct us. ● Listed products are intended for laboratory research use only, and not to be used for drug, food or human use. 11 n Angiotensin II Receptor Blockers (ARB) Product Name Valsartan for Biochemistry Wako Cat. No. 225-01991 221-01993 Pkg. Size 1g 5g Product Name Telmisartan for Biochemistry Losartan Potassium Salt for Biochemistry 120-06111 5g 128-06112 25g Olmesartan Medoxomil for Biochemistry for Biochemistry 038-22501 50mg 034-22503 250mg Irbesartan for Biochemistry Product Name Nitrendipine for Biochemistry Wako Cat. No. 142-06411 Pkg. Size 200mg Product Name Amlodipine Besilate for Biochemistry CAS No. 39562-70-4 C18H20N2O6=360.37 [Assay] 98.0+% (HPLC) [Soluble in] Chloroform [Intended Purpose (Potency)] This product is a calcium antagonist. It binds to the N-site of the L-type voltagedependent calcium channel and inhibits calcium ion influx into cells. Nicardipine Hydrochloride for Biochemistry 145-06381 1g 141-06383 5g for Biochemistry 141-05783 145-05781 143-05782 1g 5g 25g CAS No. 21829-25-4 C17H18N2O6=346.33 [Assay] 99.0+% (Absorptiometry) [Soluble in] Acetone [Intended Purpose (Potency)] This product is a calcium antagonist. It binds to the N-site of the L-type voltagedependent calcium channel and inhibits calcium ion influx into cells. 12 Active Pharmaceutical Ingredients -Catalog- 250mg 1g 157-03081 100mg 153-03083 500mg 092-06561 1g 098-06563 5g Wako Cat. No. 017-18181 013-18183 Pkg. Size 10mg 50mg CAS No. 111470-99-6 C26H31ClN2O8S=567.05 [Assay] 98.0+% (HPLC) [Soluble in] Methanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is a calcium antagonist. It binds to the N-site of the L-type voltagedependent calcium channel and inhibits calcium ion influx into cells. Nisoldipine for Biochemistry CAS No. 54527-84-3 C26H29N3O6 · HCl=515.99 [Assay] 99.0+% (HPLC) [Soluble in] Methanol [Intended Purpose (Potency)] This product is a calcium antagonist. It binds to the N-site of the L-type voltagedependent calcium channel and inhibits calcium ion influx into cells. Nifedipine 205-19003 Pkg. Size CAS No. 138402-11-6 C25H28N6O=428.53 [Assay] 90.0+% (HPLC) [Soluble in] Methanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is an angiotensin II receptor blocker. It acts on angiotensin II type 1 receptors (AT1). CAS No. 145040-37-5 C33H34N6O6=610.66 [Assay] 90.0+% (HPLC) [Soluble in] Methanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is an angiotensin II receptor blocker. It acts on angiotensin II type 1 receptors (AT1). n Calcium Antagonists CAS No. 144689-63-4 C29H30N6O6=558.59 [Assay] 90.0+% (HPLC) [Soluble in] Methanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is an angiotensin II receptor blocker. It acts on angiotensin II type 1 receptors (AT1). CAS No. 124750-99-8 C22H22ClKN6O=461.00 [Assay] 90.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is an angiotensin II receptor blocker. It acts on angiotensin II type 1 receptors (AT1). Candesartan Cilexetil 209-19001 CAS No. 144701-48-4 C33H30N4O2=514.62 [Assay] 90.0+% (HPLC) [Soluble in] DMSO [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is an angiotensin II receptor blocker. It acts on angiotensin II type 1 receptors (AT1). CAS No. 137862-53-4 C24H29N5O3=435.52 [Assay] 90.0+% (HPLC) [Soluble in] Methanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is an angiotensin II receptor blocker. It acts on angiotensin II type 1 receptors (AT1). 3 Wako Cat. No. 141-07101 10mg 147-07103 50mg CAS No. 63675-72-9 C20H24N2O6=388.41 [Assay] 97.0+% (HPLC) [Soluble in] Methanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is a calcium antagonist. It binds to the N-site of the L-type voltagedependent calcium channel and inhibits calcium ion influx into cells. Diltiazem Hydrochloride for Biochemistry 047-20311 1g 043-20313 5g CAS No. 33286-22-5 C22H26N2O4S · HCl=450.98 [Assay] 98.0+% (Titration) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is a calcium antagonist. It binds to the N-site of the L-type voltagedependent calcium channel and inhibits calcium ion influx into cells. Please visit the Wako Online Catalog: http://www.e-reagent.com Product Name Verapamil Hydrochloride for Biochemistry Wako Cat. No. Pkg. Size 222-00781 1g 228-00783 10g Product Name Amlodipine for Cellbiology Product Name Prazosin Hydrochloride for Biochemistry for Pharmacology Research Wako Cat. No. 160-25591 166-25593 Pkg. Size 100mg 1g Pindolol Product Name for Biochemistry for Biochemistry 017-24953 Pkg. Size 100mg 1g 135-15751 5g 131-15753 100g 167-11593 161-11591 169-11592 Wako Cat. No. 166-13001 162-13003 Pkg. Size 1g 5g CAS No. 13523-86-9 C14H20N2O2=248.32 [Assay] 98.0+% (Titration) [Soluble in] Acetic Acid [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is a selective β1 blocker. Atenolol for Biochemistry CAS No. 56392-17-7 (C15H25NO3) 2 · C4H6O6=684.81 [Assay] 98.0+% [Soluble in] Water [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] This product is a selective β1 blocker. (±)-Propranolol Hydrochloride 3 CAS No. 19237-84-4 C19H21N5O4 · HCl=419.86 [Assay] 97.0+% (HPLC) [Soluble in] Methanol [Intended Purpose (Potency)] This product is an α1 receptor blocker. Metoprolol Tartrate (mixture of isomers) 011-24951 CAS No. 88150-42-9 C20H25ClN2O5=408.88 [Assay] 98.0+% (HPLC) [Soluble in] Methanol [Intended Purpose (Potency)] This product is a calcium antagonist. It binds to the N-site of the L-type voltagedependent calcium channel and inhibits calcium ion influx into cells. CAS No. 152-11-4 C27H38N2O4 · HCl=491.06 [Assay] 98.0+% (Titration) [Soluble in] Water [Intended Purpose (Potency)] This product is a calcium antagonist. It binds to the N-site of the L-type voltagedependent calcium channel and inhibits calcium ion influx into cells. n α-β blockers Wako Cat. No. 015-13481 5g CAS No. 29122-68-7 C14H22N2O3=266.34 [Assay] 98.0+% (Titration) [Soluble in] Ethanol [Intended Purpose (Potency)] This product is a selective β1 blocker. 1g 5g 25g CAS No. 3506-09-0 C16H21NO2 · HCl=295.80 [Assay] 99.0+% (Titration) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is a selective β1 blocker. n Other Antihypertensives Product Name Spironolactone for Pharmacology Research Wako Cat. No. 191-16871 197-16873 Pkg. Size 1g 5g Product Name Bosentan Hydrate for Pharmacology Research CAS No. 52-01-7 C24H32O4S=416.57 [Assay] 98.0+% (HPLC) [Soluble in] Methanol [Intended Purpose (Potency)] This product is an aldosterone antagonist. Wako Cat. No. 020-18351 026-18353 Pkg. Size 1mg 10mg CAS No. 157212-55-0 C27H29N5O6S · H2O=569.63 [Assay] 98.0+% (HPLC) [Soluble in] Ethanol [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] This product exhibits antagonism to endothelin receptors (ETA and ETB). It improves pulmonary hypertension. n Anti-Cardiac Failure Agents Product Name Digitoxin Wako 1st Grade Wako Cat. No. 046-25261 Pkg. Size 1g Product Name Aminophylline for Biochemistry CAS No. 71-63-6 C41H64O13=764.95 [Assay] 98.0+% (HPLC) [Soluble in] Ethanol [Intended Purpose (Potency)] This product is a cardiac glycoside. It inhibits Na+/K+-ATPase. ● If no storage conditions are specified, store at room temperature. ● Bulk quote requests for some products are welcomed. Please contuct us. ● Listed products are intended for laboratory research use only, and not to be used for drug, food or human use. Wako Cat. No. 017-24431 013-24433 Pkg. Size 10g 50g CAS No. 317-34-0 C14H16N8O4 · C2H8N2=420.43 [Soluble in] Water [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] This product is a complex composed of 2 molecules of theophylline and 1 molecule of ethylenediamine. It acts as theophylline in the living body. It inhibits phosphodiesterase. 13 Product Name Milrinone for Biochemistry Wako Cat. No. 138-13801 134-13803 132-13804 Pkg. Size 10mg 100mg 1g Product Name Ubiquinone-10 for Biochemistry 3,4-Dihydroxyphenethylamine Hydrochloride (Dopamine Chloride) Wako Special Grade 044-15431 040-15433 048-15434 042-15432 100mg 1g 5g 25g 216-00761 212-00763 Pkg. Size 10mg 100mg CAS No. 303-98-0 C59H90O4=863.34 [Assay] 98.0+% (HPLC) [Soluble in] Hexane [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] This product acts as an energetic coenzyme for the mitochondria in cells. CAS No. 78415-72-2 C12H9N3O=211.22 [Assay] 96.0+% (Titration) [Soluble in] Methanol [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] Powerful drug-III 3 Wako Cat. No. Dobutamine Hydrochloride for Biochemistry 046-32611 20mg 042-32613 200mg CAS No. 49745-95-1 C18H23NO3 · HCl=337.84 [Assay] 90.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product enhances myocardial function. CAS No. 62-31-7 C8H11NO2 · HCl=189.64 [Assay] 95.0+% (Titration) [Soluble in] Water [Intended Purpose (Potency)] This product activates adenylyl cyclase by β1 receptor stimulation. n Antianginal Agents Product Name Nicorandil for Biochemistry Wako Cat. No. 141-07221 Pkg. Size 1g Product Name Dipyridamole for Biochemistry CAS No. 65141-46-0 C8H9N3O4=211.17 [Assay] 98.0+% (Titration) [Soluble in] Ethanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product activates guanylate cyclase and increases cyclic GMP (cGMP). Wako Cat. No. 042-22463 046-22461 Pkg. Size 1g 5g CAS No. 58-32-2 C24H40N8O4=504.63 [Assay] 98.0+% (HPLC) [Soluble in] Chloroform [Intended Purpose (Potency)] This product acts as a coronary vasodilator. n Antiarrhythmic Agents Product Name Quinidine Sulfate Dihydrate Wako Cat. No. 173-00121 171-00122 Pkg. Size 5g 25g Product Name Mexiletine Hydrochloride for Biochemistry CAS No. 6591-63-5 (C20H24N2O2) 2 · H2SO4 · 2H2O=782.94 [Assay] 98.0+% (Titration) [Soluble in] Diluted hydrochloric acid [Intended Purpose (Potency)] This product blocks sodium channels and prolongs the duration of action potential. Disopyramide for Biochemistry 046-21741 1g 042-21743 10g Wako Cat. No. 132-17581 138-17583 Pkg. Size 1g 5g CAS No. 5370-01-4 C11H17NO · HCl=215.72 [Assay] 90.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product blocks sodium channels and prolongs the duration of action potential. Propafenone Hydrochloride for Biochemistry CAS No. 3737-09-5 C21H29N3O=339.48 [Assay] 98.5+% (Titration) [Soluble in] Ethanol [Intended Purpose (Potency)] This product blocks sodium channels and prolongs the duration of action potential. 169-25681 100mg 165-25683 500mg CAS No. 34183-22-7 C21H27NO3 · HCl=377.90 [Assay] 90.0+% (HPLC) [Soluble in] Methanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product blocks sodium channels and inhibits the initiation of action potential. n Antihypotensives Product Name Midodrine Hydrochloride for Pharmacology Research Wako Cat. No. 134-15581 Pkg. Size 500mg CAS No. 3092-17-9 C12H18N2O4 · HCl=290.74 [Assay] 98.0+% (HPLC) [Soluble in] Water [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] This product acts as a selective α1 receptor agonist. 14 Active Pharmaceutical Ingredients -Catalog- Product Name Dihydroergotamine Mesylate for Pharmacology Research Wako Cat. No. 041-30601 049-30602 Pkg. Size 1g 25g CAS No. 6190-39-2 C33H37N5O5 · CH4O3S=679.78 [Assay] 96.0+% (Titration) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product acts as a vasoconstrictor. Please visit the Wako Online Catalog: http://www.e-reagent.com n Antispasmodic Agent Product Name Wako Cat. No. Papaverine Hydrochloride Wako 1st Grade 166-18001 164-18002 Pkg. Size 5g 25g CAS No. 61-25-6 C20H21NO4 · HCl=375.85 [Assay] 98.0+% (Titration) [Soluble in] Water [Intended Purpose (Potency)] It inhibits phosphodiesterase. 3 4 4. Agents Acting on Respiratory System n Anti-Asthmatic Agents n β receptor agonists Product Name Wako Cat. No. Tulobuterol (mixture of isomers) 202-17031 for Pharmacology Research Pkg. Size 200mg Product Name Fenoterol Hydrobromide for Biochemistry CAS No. 41570-61-0 C12H18ClNO=227.73 [Assay] 98.0+% (HPLC) [Soluble in] Methanol [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] Selective β2 adrenergic agonist. Terbutaline Sulfate for Pharmacology Research 208-19191 1g 204-19193 5g Practical Grade 196-10081 250mg 192-10083 1g Methoxyphenamine Hydrochloride for Biochemistry Product Name Ozagrel Sodium Salt for Biochemistry Wako Cat. No. 154-03111 150-03113 Pkg. Size 500mg 2g 066-06103 Pkg. Size 1g 5g 138-17561 10g 134-17563 50g CAS No. 5588-10-3 C11H17NO · HCl=215.72 [Assay] 90.0+% (Titration) [Soluble in] Water [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] Selective β2 adrenergic agonist. Procaterol Hydrochloride Hemihydrate for Biochemistry CAS No. 51022-70-9 (C13H21NO3) 2 · H2SO4=576.70 [Assay] 98.0+% (Titration) [Soluble in] Water [Intended Purpose (Potency)] Selective β2 adrenergic agonist. n Other Anti-Asthmatic Agents 060-06101 CAS No. 1944-12-3 C17H21NO4 · HBr=384.26 [Assay] 90.0+% (Titration) [Soluble in] Water [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] Selective β2 adrenergic agonist. CAS No. 23031-32-5 (C12H19NO3) 2 · H2SO4=548.65 [Assay] 98.0+% (HPLC) [Soluble in] Water [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] Selective β2 adrenergic agonist. Salbutamol Sulfate Wako Cat. No. 160-19861 10mg 166-19863 50mg CAS No. 62929-91-3 C16H22N2O3 · HCl · 0.5H2O=335.83 [Assay] 98.0+% (HPLC) [Soluble in] Water-Methanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] Selective β2 adrenergic agonist. Product Name Pranlukast for Biochemistry CAS No. 189224-26-8 C13H11N2NaO2=250.23 [Assay] 98.0+% (HPLC) [Soluble in] Water [Intended Purpose (Potency)] This product is an antithromboxane agent. It acts as a thromboxane synthase inhibitor. ● If no storage conditions are specified, store at room temperature. ● Bulk quote requests for some products are welcomed. Please contuct us. ● Listed products are intended for laboratory research use only, and not to be used for drug, food or human use. Wako Cat. No. 168-25771 164-25773 Pkg. Size 10mg 100mg CAS No. 103177-37-3 C27H23N5O4=481.50 [Assay] 90.0+% (HPLC) [Soluble in] DMSO [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] Selectively inhibits leukotriene receptors that are involved in bronchial asthma and allergic rhinitis. 15 Product Name Aminophylline for Biochemistry Wako Cat. No. 017-24431 013-24433 Pkg. Size 10g 50g CAS No. 317-34-0 C14H16N8O4 · C2H8N2=420.43 [Assay] Theophylline: 84.0 - 87.4%; Ethylenediamine: 13.5 - 15.0% [Soluble in] Water [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] cAMP phosphodiesterase inhibitor composed of theophylline and ethylenediamine at a ratio of 2:1 4 n Expectorants Product Name Bromhexine Hydrochloride for Pharmacology Research Wako Cat. No. 020-15931 028-15932 Pkg. Size 5g 25g Product Name L-Cysteine Ethyl Ester Hydrochloride for Biochemistry CAS No. 611-75-6 C14H20Br2N2 · HCl=412.59 [Assay] 98.0+% [Soluble in] Formic acid, methanol [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] This product is a compound to promote secretion in the respiratory tract. It acts as a mucolytic by lysosomal enzymes. L-Cysteine Wako Special Grade 039-20652 25g 033-20655 500g Wako 1st Grade 039-09451 5g CAS No. 18598-63-5 C4H9NO2S · HCl=171.65 [Assay] 95.0+% (Titration) [Soluble in] Water [Intended Purpose (Potency)] This product is a compound containing an SH group. It dissociates disulfide bonds in mucoproteins of mucus. N -Acetyl-L-cysteine Wako Special Grade 017-05131 015-05132 013-05133 5g 25g 100g CAS No. 616-91-1 C5H9NO3S=163.19 [Assay] 98.0+% (Titration) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is a compound containing an SH group. It dissociates disulfide bonds in mucoproteins of mucus. 033-22752 035-22751 Pkg. Size 25g 100g CAS No. 868-59-7 C5H11NO2S · HCl=185.67 [Assay] 95.0+% (Titration) [Soluble in] Water [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] This product is a compound containing an SH group. It dissociates disulfide bonds in mucoproteins of mucus. Ambroxol Hydrochloride for Biochemistry CAS No. 52-90-4 C3H7NO2S=121.16 [Assay] 98.0+% (Titration) [Soluble in] Water [Intended Purpose (Potency)] This product is a compound containing an SH group. It dissociates disulfide bonds in mucoproteins of mucus. L (−)-Cysteine Methyl Ester Hydrochloride Wako Cat. No. 017-18941 1g 013-18943 5g CAS No. 18683-91-5 C13H18Br2N2O · HCl=414.56 [Assay] 97.0+% (Titration) [Soluble in] Methanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product increases the secretion of active metabolites on the alveolar surface. Lysozyme, from Egg White for Biochemistry — S -(Carboxymethyl)-L-cysteine 126-02671 122-02673 120-02674 1g 5g 10g CAS No. 12650-88-3 Molecular weight: approx. 14,000 [Potency] (calculated on the dried basis) 0.8+ mg Lysozyme/mg [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is a polysaccharidedegrading enzyme. It decomposes mucopolysaccharide. 325-41722 25g 323-41723 100g CAS No. 638-23-3 C5H9NO4S=179.19 [Assay] 97.0+% [Soluble in] Dilute hydrochloric acid, Sodium hydroxide solution [Intended Purpose (Potency)] This product is a compound containing an SH group. It dissociates disulfide bonds in mucoproteins of mucus. n Antitussive Agent Product Name Chloperastine Hydrochloride for Biochemistry Wako Cat. No. 035-13282 Pkg. Size 25g CAS No. 14984-68-0 C20H24ClNO · HCl=366.32 [Assay] 98.0+% (Titration) (after drying) [Soluble in] Water [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] This product is believed to act on the center. 16 Active Pharmaceutical Ingredients -Catalog- Please visit the Wako Online Catalog: http://www.e-reagent.com 5. Agents Acting on Digestive System n Antiulcer Agents n Hstamine H2 receptor antagonists Product Name Ranitidine Hydrochloride for Biochemistry Wako Cat. No. 185-01564 181-01561 187-01563 Pkg. Size 500mg 5g 25g Product Name Famotidine for Biochemistry for Pharmacology Research 147-08541 5g 145-08542 25g Product Name Lansoprazole for Pharmacology Research Wako Cat. No. 123-05861 129-05863 Pkg. Size 250mg 1g Cimetidine for Biochemistry Product Name (±)-Sulpiride for Biochemistry Wako Cat. No. 190-12061 198-12062 196-12063 Pkg. Size 1g 25g 100g Product Name Omeprazole for Biochemistry 320-20571 10g 328-20572 25g 065-03932 25g 036-16311 5g 034-16312 25g Wako Cat. No. 150-02091 158-02092 Pkg. Size 10g 25g CAS No. 73590-58-6 C17H19N3O3S=345.42 [Assay] 98.0+% (HPLC) [Soluble in] Dichloromethane [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] The product is a proton pump inhibitor. It transfers to parietal cells, that are gastric acid production cells, and reduce gastric acid secretion by strongly inhibiting the H+, K+-ATPase activity. Product Name 5-Aminosalicylic Acid Wako Cat. No. Pkg. Size 329-26462 25g 323-26465 500g CAS No. 89-57-6 C7H7NO3=153.14 [Assay] 97.0+% (HPLC) [Intended Purpose (Potency)] The product is a sulfa drug. The azo group reductively cleaves by enteric bacteria and anti-inflammatory effect is shown. CAS No. 15676-16-1 C15H23N3O4S=341.43 [Assay] 98.0+% (Titration) [Soluble in] Dilute acetic acid [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] The product is a dopamine D2 receptor antagonist. It releases acetylcholine by a specific antagonistic action of the dopamine D2 receptor. Guaiazulene 5g CAS No. 51481-61-9 C10H16N6S=252.34 [Assay] 98.0+% (HPLC) [Soluble in] Methanol [Intended Purpose (Potency)] It shows a histamine H2 receptor blocking activity. It also shows an anti-androgenic activity. CAS No. 103577-45-3 C16H14F3N3O2S=369.36 [Assay] 97.0+% (HPLC) [Soluble in] N,N- Dimethylformamide [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] The product is a proton pump inhibitor. It transfers to parietal cells, that are gastric acid production cells, and reduce gastric acid secretion by strongly inhibiting the H+, K+-ATPase activity. n Other antiulcer agents 5 CAS No. 76963-41-2 C12H21N5O2S2=331.46 [Assay] 98.0+% (HPLC) [Soluble in] Methanol [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] The product is a histamine H2 receptor antagonist. It blocks histamine H2 receptors in the gastric mucosa and shows a gastric antisecretory activity. n Proton pump inhibitors Pkg. Size 067-03931 CAS No. 76824-35-6 C8H15N7O2S3=337.45 [Assay] 98.0+% (Titration) [Soluble in] Dilute hydrochloric acid [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] The product is a histamine H2 receptor antagonist. It blocks histamine H2 receptors in the gastric mucosa and shows a gastric antisecretory activity. CAS No. 66357-59-3 C13H22N4O3S · HCl=350.86 [Assay] 97.0+% (Titration) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] The product is a histamine H2 receptor antagonist. It blocks histamine H2 receptors in the gastric mucosa and shows a gastric antisecretory activity. The H2 antagonistic action is more than 10 times higher than cimetidine. It has a pepsin secretion inhibitory activity. Nizatidine Wako Cat. No. Aldioxa for Pharmacology Research CAS No. 489-84-9 C15H18=198.31 [Assay] 96.0+% [Soluble in] Sufuric acid, phosphoric acid [Intended Purpose (Potency)] It has been said to have anti-inflammatory effects. ● If no storage conditions are specified, store at room temperature. ● Bulk quote requests for some products are welcomed. Please contuct us. ● Listed products are intended for laboratory research use only, and not to be used for drug, food or human use. 019-21211 5g 017-21212 25g CAS No. 5579-81-7 C4H7AlN4O5=218.10 [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] The product is an antipepsin compound. It inhibits a peptic activity. 17 Product Name Teprenone (mixture of isomers) for Biochemistry Wako Cat. No. 206-15731 202-15733 Pkg. Size 1g 5g Product Name Irsogladine Maleate for Biochemistry CAS No. 6809-52-5 C23H38O=330.55 [Assay] 97.0+% (HPLC) [Intended Purpose (Potency)] It promotes biosynthesis of prostaglandin (PGE2, PGI2). Sofalcone for Pharmacology Research 195-14831 5g 193-14832 25g 098-04581 094-04583 Pkg. Size 100mg 500mg CAS No. 84504-69-8 C9H7Cl2N5 · C4H4O4=372.16 [Assay] 97.0+% (Titration) [Soluble in] Methanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] It shows an increasing effect on cAMP in the gastric mucosa. Sodium Alginate 80-120 Wako 1st Grade CAS No. 64506-49-6 C27H30O6=450.52 [Assay] 97.0+% [Soluble in] Methanol [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] It shows an increasing effect on secretion of prostaglandin. 5 Wako Cat. No. — 194-13321 100g 196-13325 500g CAS No. 9005-38-3 [Soluble in] Water (It becomes viscous and pasty liquid) [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] It shows a protective effect on the gastric mucosa. n Antacids Product Name Wako Cat. No. 131-00282 133-00281 135-00285 Magnesium Oxide JIS Special Grade Pkg. Size 25g 100g 500g Product Name Wako Cat. No. Sodium Hydrogen Carbonate 195-14515 193-14511 for Molecular Biology CAS No. 1309-48-4 MgO=40.30 [Assay] 98.0+% (mass/mass) (Titration) [Intended Purpose (Potency)] It shows an antacid effect. MgO — Pkg. Size 500g 1kg CAS No. 144-55-8 NaHCO3=84.01 [Assay] 99.5 - 100.3% (Titration) [Soluble in] Water [Intended Purpose (Potency)] It neutralizes gastric acid and reduces acidity. n Emetic Agents/Antiemetic Agents Product Name Wako Cat. No. Domperidone for Biochemistry 044-32651 040-32653 Pkg. Size 100mg 500mg Product Name Metoclopramide for Biochemistry for Biochemistry 093-06591 1g 099-06593 5g CAS No. 122892-31-3 C20H26N2O4 · HCl=394.89 [Assay] 90.0+% (Titration) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] It shows a dopamine D2 receptor blocking activity. Azasetron Hydrochloride for Biochemistry Cl CH3 N O H ・HCl 18 N N O O 014-24441 50mg 010-24443 200mg 138-10182 Pkg. Size 25g CAS No. 364-62-5 C14H22ClN3O2=299.80 [Assay] 98.5+% (Titration) [Soluble in] Dilute hydrochloric acid [Intended Purpose (Potency)] The product is a 5-HT3 receptor antagonist. It shows a dopamine D2 receptor blocking activity. CAS No. 57808-66-9 C22H24ClN5O2=425.91 [Assay] 90.0+% (HPLC) [Soluble in] Methanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] It shows a dopamine D2 receptor blocking activity. Itopride Hydrochloride Wako Cat. No. Granisetron Hydrochloride for Pharmacology Research 073-06131 5mg 079-06133 50mg CAS No. 107007-99-8 C18H24N4O · HCl=348.87 [Assay] 98.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] The product is a 5-HT3 receptor antagonist type antiemetic agent. It binds to serotonin 5-HT3 receptors. CAS No. 123040-16-4 C17H20ClN3O3 · HCl=386.27 [Assay] 90.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] The product is a 5-HT3 receptor antagonist type antiemetic agent. It binds to serotonin 5-HT3 receptors. Active Pharmaceutical Ingredients -Catalog- Please visit the Wako Online Catalog: http://www.e-reagent.com n Antidiarrheal Agents Product Name Loperamide Hydrochloride for Pharmacology Research Wako Cat. No. 129-05721 127-05722 Pkg. Size 5g 25g Product Name Berberine Chloride for Biochemistry CAS No. 34552-83-5 C29H33ClN2O2 · HCl=513.50 [Assay] 97.0+% (Titration) [Soluble in] Ethanol [Intended Purpose (Potency)] It affects on opioid receptors in the intestinal tract and shows inhibitory effects on peristaltic movement of the intestinal tract. It also shows inhibitory effects on acetylcholine release. Bismuth (III) Carbonate Basic Wako 1st Grade (BiO) 2CO3 020-01962 25g 024-01965 500g Wako Cat. No. 027-11781 Pkg. Size 100mg CAS No. 633-65-8 C20H18ClNO4=371.81 [Assay] 90.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] The product is an active ingredient of a crude drug. It shows an inhibitory action on intestinal motility. CAS No. 5892-10-4 (BiO) 2CO3=509.97 [Assay] 97.0+% (Titration) [Soluble in] Nitric acid [Intended Purpose (Potency)] The product is a bismuth preparation. It has an activity to remove fluid from the intestinal tract. 5 n Cathartic Agents Product Name Sennoside A Wako Cat. No. 192-10201 for Biochemistry Pkg. Size 100mg Product Name Sennoside B for Biochemistry CAS No. 81-27-6 C42H38O20=862.74 [Assay] 90.0+% (HPLC) [Soluble in] Sodium hydrogen carbonate solution. [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] An active component of rheum (Rhei Rhizoma). It possesses cathartic activity. Sodium Picosulfate n -Hydrate for Biochemistry 197-17191 50mg 193-17193 250mg Wako Cat. No. 199-10211 Pkg. Size 100mg CAS No. 128-57-4 C42H38O20=862.74 [Assay] 90.0+% (HPLC) [Soluble in] Sodium hydrogen carbonate solution. [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] An active component of rheum (Rhei Rhizoma). It possesses cathartic activity. CAS No. 10040-45-6 C18H13NNa2O8S2 · nH2O (C18H13NNa2O8S2=481.41) [Assay] 90.0+% (HPLC) [Soluble in] Water [Intended Purpose (Potency)] Hydrolyzed to active diphenol in the large intestine by a flora-derived enzyme. Facilitates peristaltic movement and inhibits water absorption directly in the large intestine and shows cathartic effect. A laxative. n Other Gastrointestinal Agents Product Name Pilocarpine Hydrochloride Wako Special Grade Wako Cat. No. 161-07201 169-07202 Pkg. Size 1g 25g Product Name Polaprezinc for Biochemistry CAS No. 54-71-7 C11H16N2O2 · HCl=244.72 [Assay] 99.0+% (Titration) [Soluble in] Water [Intended Purpose (Potency)] The product is a cholinergic alkaloidal agent. It has a sustained muscarinic effect. It also shows a glandular secretory activity. Calcium Polycarbophil for Biochemistry — 035-22631 5g 033-22632 25g Wako Cat. No. 166-25711 162-25713 Pkg. Size 100mg 500mg CAS No. 107667-60-7 C9H12N4O3Zn=289.60 [Assay] 90.0+% (HPLC) [Soluble in] Dilute hydrochloric acid [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] Polaprezinc is a reagent comprised of the complex of zinc and L-carnosine. Zinc is a biological essential trace element, having various physiological activities, such as wound-healing action, antiulcer action and anti-inflammatory action. CAS No. 126040-58-2 [Intended Purpose (Potency)] The product is a synthetic macromolecular compound by bridging a polyacrylic acid with 3,4-Dihydroxy-1,5-hexadiene. After calcium release, it absorbs large quantities of water and swells/gelates under the neutral condition. ● If no storage conditions are specified, store at room temperature. ● Bulk quote requests for some products are welcomed. Please contuct us. ● Listed products are intended for laboratory research use only, and not to be used for drug, food or human use. 19 6. Agents Acting on Endocrine Metabolic Disease n Lipid-Lowering Agents n HMG-CoA reductase inhibitors Product Name Simvastatin for Biochemistry Wako Cat. No. 193-12051 199-12053 Pkg. Size 25mg 100mg Product Name Rosuvastatin Calcium Salt for Biochemistry CAS No. 79902-63-9 C25H38O5=418.57 [Assay] 98.0+% (HPLC) [Soluble in] Acetonitrile [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] The product is a HMG-CoA reductase inhibitor. It shows an inhibitory action by suppressing cholesterol synthesis by inhibiting HMG-CoA (3-Hydroxy-3methylglutaryl-coenzyme A) reductase. Fluvastatin Sodium for Pharmacology Research 069-05571 50mg 065-05573 500mg n Blood lipoprotein lipase (LPL) activators Product Name Bezafibrate for Pharmacology Research Wako Cat. No. 022-16091 028-16093 Pkg. Size 5g 100g Pravastatin Sodium Salt for Biochemistry for Cellbiology 060-05361 068-05362 066-05363 182-02733 Pkg. Size 50mg 250mg 162-19821 25mg 168-19823 100mg CAS No. 81131-70-6 C23H35NaO7=446.51 [Assay] 98.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] The product is a HMG-CoA reductase inhibitor. It shows an inhibitory action by suppressing cholesterol synthesis by inhibiting HMG-CoA (3-Hydroxy-3methylglutaryl-coenzyme A) reductase. Product Name Ciprofibrate for Cellbiology CAS No. 41859-67-0 C19H20ClNO4=361.82 [Assay] 97.0+% [Soluble in] N,N- Dimethylformamide [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] The product is a fibrate blood lipoprotein lipase (LPL) activator. It shows a triglyceride hydrolytic action by activation of lipoproteins. Fenofibrate 186-02731 CAS No. 147098-20-2 (C22H27FN3O6S) 2Ca=1001.14 [Assay] 90.0+% (HPLC) [Soluble in] Methanol [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] The product is a HMG-CoA reductase inhibitor. It shows an inhibitory action by suppressing cholesterol synthesis by inhibiting HMG-CoA (3-Hydroxy-3methylglutaryl-coenzyme A) reductase. CAS No. 93957-55-2 C24H25FNNaO4=433.45 [Assay] 98.0+% (HPLC) [Soluble in] Methanol [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] The product is a HMG-CoA reductase inhibitor. It shows an inhibitory action by suppressing cholesterol synthesis by inhibiting HMG-CoA (3-Hydroxy-3methylglutaryl-coenzyme A) reductase. 6 Wako Cat. No. Wako Cat. No. 033-21191 039-21193 Pkg. Size 25mg 100mg CAS No. 52214-84-3 C13H14Cl2O3=289.15 [Assay] 98.0+% (HPLC) [Soluble in] Water-Acetonitrile [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] The product is a fibrate blood lipoprotein lipase (LPL) activator. It shows a triglyceride hydrolytic action by activation of lipoproteins. 5g 25g 100g CAS No. 49562-28-9 C20H21ClO4=360.83 [Assay] 98.0+% (HPLC) [Soluble in] Ethanol [Intended Purpose (Potency)] The product is a fibrate blood lipoprotein lipase (LPL) activator. It shows a triglyceride hydrolytic action by activation of lipoproteins. n Other lipid-lowering agents Product Name γ-Oryzanol for Biochemistry Wako Cat. No. 152-01272 154-01271 Pkg. Size 25g 100g CAS No. 11042-64-1 C40H58O4=602.89 [Assay] 97.0+% [Soluble in] Acetone [Intended Purpose (Potency)] It shows a cholesterol absorption inhibitory action. Probucol for Biochemistry 162-20311 166-20314 168-20313 Product Name (±)-α-Tocopherol Nicotinate for Biochemistry Wako Cat. No. 208-09181 206-09182 Pkg. Size 5g 25g CAS No. 51898-34-1 C35H53NO3=535.80 [Assay] 96.0+% (HPLC) [Soluble in] Ethanol [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] It shows activity to reduce cholesterol and triglyceride. 1g 5g 10g CAS No. 23288-49-5 C31H48O2S2=516.84 [Assay] 97.0+% (HPLC) [Soluble in] Ethanol [Intended Purpose (Potency)] It shows a cholesterol biosynthesis inhibitory action. 20 Active Pharmaceutical Ingredients -Catalog- Please visit the Wako Online Catalog: http://www.e-reagent.com n Diabetes Agents n Sulfonylurea(SU) agents Product Name Gliclazide Wako Cat. No. for Biochemistry 071-04731 079-04732 Pkg. Size 10g 25g Product Name Glimepiride for Pharmacology Research CAS No. 21187-98-4 C15H21N3O3S=323.41 [Assay] 98.0+% (Titration) [Soluble in] N,N- Dimethylformamide [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] The product is a sulfonylurea agent (SU agent). It promotes insulin secretion by binding to a SU receptor in the cell membrane of the pancreatic β cells and blocking potassium channels. Mitiglinide Calcium Dihydrate 139-16991 for Pharmacology Research 10mg for Pharmacology Research 032-21482 25g 034-21481 100g Glibenclamide for Biochemistry Product Name Metformin Hydrochloride for Pharmacology Research Wako Cat. No. 138-15481 130-15485 Pkg. Size 100g 500g Tolbutamide for Biochemistry Product Name Acarbose for Pharmacology Research Wako Cat. No. Product Name Buformine Hydrochloride for Biochemistry 1g 015-22673 10g Product Name Miglitol for Pharmacology Research CAS No. 56180-94-0 C25H43NO18=645.60 [Assay] 95.0+% (HPLC) [Soluble in] Water [Intended Purpose (Potency)] The product is an α-glucosidase inhibitor. It blocks α-glucosidases that digest disaccharides to monosaccharides and retard digestion and absorption of carbohydrates. Voglibose for Pharmacology Research 229-01891 10mg 225-01893 1g 500mg 5g 078-03881 5g 076-03882 25g 209-09172 6 25g Wako Cat. No. 028-10052 Pkg. Size 25g CAS No. 1190-53-0 C6H15N5 · HCl=193.68 [Assay] 98.0+% (Titration) [Soluble in] Water [Intended Purpose (Potency)] The product is a biguanide system compound. It shows an inhibitory action on gluconeogenesis. The pancreatic β cell stimulation effect is regarded as weak. Pkg. Size 019-22671 077-05693 Pkg. Size CAS No. 64-77-7 C12H18N2O3S=270.35 [Assay] 99.0+% (Titration) [Soluble in] Ethanol [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] The product is a sulfonylurea agent (SU agent). It promotes insulin secretion by binding to a SU receptor in the cell membrane of the pancreatic β cells and blocking potassium channels. CAS No. 1115-70-4 C4H11N5 · HCl=165.62 [Assay] 98.0+% (Titration) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] The product is a biguanide system compound. It shows an inhibitory action on gluconeogenesis. The pancreatic β cell stimulation effect is regarded as weak. n α-glucosidase inhibitors CAS No. 10238-21-8 C23H28ClN3O5S=494.00 [Assay] 98.0+% (Titration) [Soluble in] N,N- Dimethylformamide [Intended Purpose (Potency)] The product is a sulfonylurea agent (SU agent). It promotes insulin secretion by binding to a SU receptor in the cell membrane of the pancreatic β cells and blocking potassium channels. CAS No. 94-20-2 C10H13ClN2O3S=276.74 [Assay] 97.0+% (HPLC) [Soluble in] Methanol [Intended Purpose (Potency)] The product is a sulfonylurea agent (SU agent). It promotes insulin secretion by binding to a SU receptor in the cell membrane of the pancreatic β cells and blocking potassium channels. n Biguanide system compounds 071-05691 CAS No. 93479-97-1 C24H34N4O5S=490.62 [Assay] 98.0+% (HPLC) [Soluble in] DMSO [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] The product is a sulfonylurea agent (SU agent). It promotes insulin secretion by binding to a SU receptor in the cell membrane of the pancreatic β cells and blocking potassium channels. CAS No. 207844-01-7 C38H48CaN2O6 · 2H2O=704.91 [Assay] 98.0+% (HPLC) [Soluble in] Methanol [Intended Purpose (Potency)] The product is a sulfonylurea agent (SU agent). It promotes insulin secretion by binding to a SU receptor in the cell membrane of the pancreatic β cells and blocking potassium channels. Chlorpropamide Wako Cat. No. Wako Cat. No. 138-16221 134-16223 132-16224 Pkg. Size 10mg 100mg 1g CAS No. 72432-03-2 C8H17NO5=207.22 [Assay] 97.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] The product is an α-glucosidase inhibitor. It blocks α-glucosidases that digest disaccharides to monosaccharides and retard digestion and absorption of carbohydrates. CAS No. 83480-29-9 C10H21NO7=267.28 [Soluble in] Water [Intended Purpose (Potency)] The product is an α-glucosidase inhibitor. It blocks α-glucosidases that digest disaccharides to monosaccharides and retard digestion and absorption of carbohydrates. ● If no storage conditions are specified, store at room temperature. ● Bulk quote requests for some products are welcomed. Please contuct us. ● Listed products are intended for laboratory research use only, and not to be used for drug, food or human use. 21 n Other diabetes drugs Product Name Epalrestat for Pharmacology Research Wako Cat. No. 058-07701 054-07703 Pkg. Size 1g 5g Product Name Glucagon Hydrochloride (Human) Wako 1st Grade CAS No. 82159-09-9 C15H13NO3S2=319.40 [Assay] 98.0+% [Soluble in] N,N- Dimethylformamide [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] It shows an aldose reductase inhibition effect. Nateglinide for Pharmacology Research 6 148-09311 10mg 144-09313 100mg — Insulin Glargine, recombinant for Pharmacology Research CAS No. 105816-04-4 C19H27NO3=317.42 [Assay] 98.0+% (HPLC) [Soluble in] Methanol [Intended Purpose (Potency)] It is a prompt islet-activating compound. It is a phenylalanine derivative and promotes insulin secretion by binding to a SU receptor in the cell membrane of the pancreatic β cells and blocking potassium channels. Rosiglitazone for Cellbiology 184-02651 5mg 180-02653 25mg — Pioglitazone Hydrochloride for Pharmacology Research CAS No. 122320-73-4 C18H19N3O3S=357.43 [Assay] 98.0+% (HPLC) [Soluble in] Methanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] It is a thiazolidine agent that affects PPARγ and improves insulin resistance and shows a hypoglycemic effect. Wako Cat. No. 076-05401 072-05403 Pkg. Size 1mg 5mg CAS No. 9007-92-5 C153H225N43O49S · HCl=3519.21 [Assay] 97.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] It has an adenylate cyclase activity in the liver and shows a hepatic glycogenolysis effect. 092-06181 1mg 098-06183 10mg CAS No. 160337-95-1 C267H404N72O78S6=6062.89 [Soluble in] Dilute hydrochloric acid [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] It is an insulin analog, in which the asparagine to glycine substitution at position 21 in the A chain and 2 arginine residues are attached in the C-terminal of the B chain of a human insulin. Compared to insulin, it shows a longer hypoglycemic effect. 162-24831 100mg 168-24833 500mg CAS No. 112529-15-4 C19H20N2O3S · HCl=392.90 [Assay] 98.0+% (HPLC) [Soluble in] N,N -Dimethylformamide [Intended Purpose (Potency)] The product is a thiazolidine agent that affects PPARγ. It improves insulin resistance and shows a hypoglycemic effect. n Antigout Agents Product Name Colchicine Wako 1st Grade Wako Cat. No. 039-03851 035-03853 Pkg. Size 100mg 1g Product Name Probenecid for Pharmacology Research for Biochemistry 011-12501 5g 019-12502 25g 162-26112 Pkg. Size 25g CAS No. 57-66-9 C13H19NO4S=285.36 [Assay] 98.0+% (Titration) (after drying) [Soluble in] Ethanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] It inhibits tubular reabsorption and promotes uricotelism. CAS No. 64-86-8 C22H25NO6=399.44 [Assay] 95.0+% (HPLC) [Soluble in] Ethanol, Water [Intended Purpose (Potency)] It inhibits microtubule formation by specifically binding to tubulin. Allopurinol Wako Cat. No. Benzbromarone for Pharmacology Research 028-15851 5g 026-15852 25g CAS No. 3562-84-3 C17H12Br2O3=424.08 [Assay] 98.0+% (Titration) [Soluble in] Acetone [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] It selectively inhibits tubular reabsorption and increases uricotelism. CAS No. 315-30-0 C5H4N4O=136.11 [Assay] 98.0+% (Titration) [Soluble in] Sodium hydroxide solution [Intended Purpose (Potency)] It inhibits xanthine oxidase and shows inhibitory effects on production of uric acid. n Anti-Liver Disease Agents Product Name Protoporphyrinato Zinc Wako Cat. No. 167-13651 Pkg. Size 10mg CAS No. 15442-64-5 C34H32N4O4Zn=626.05 [Soluble in] N,N- Dimethylformamide, pyridine [Intended Purpose (Potency)] It promotes liver protein synthesis ability as well as decreases/inhibits liver catalase activity. 22 Active Pharmaceutical Ingredients -Catalog- Product Name L (+)-Glutamine JIS Special Grade Wako Cat. No. 076-00521 074-00522 072-00523 078-00525 Pkg. Size 5g 25g 100g 500g CAS No. 56-85-9 C5H10N2O3=146.15 [Assay] 99.0+% (Titration) [Soluble in] Water [Intended Purpose (Potency)] It binds to ammonia and decreases the level of ammonia. Please visit the Wako Online Catalog: http://www.e-reagent.com n Diuretic Agents Product Name 2-Acetamido-5-sulfonamido1,3,4-thiadiazole Wako Cat. No. 351-18791 359-18792 Pkg. Size 5g 25g Product Name Methyclothiazide for Biochemistry CAS No. 59-66-5 C4H6N4O3S2=222.25 [Assay] 97.0+% [Soluble in] Water [Intended Purpose (Potency)] The product is a carbonic anhydrase inhibitor. It shows a carbonic anhydrase inhibitory effect. Hydrochlorothiazide Wako Special Grade 086-07901 5g 084-07902 25g Wako Cat. No. 135-13931 131-13933 Pkg. Size 1g 5g CAS No. 135-07-9 C9H11Cl2N3O4S2=360.24 [Assay] 95.0+% (Titration) [Soluble in] Acetone [Intended Purpose (Potency)] The product is a thiazide diuretic agent. It directly affects on the renal tubules and inhibits reabsorption of sodium and simultaneously excretes chloride ions balancing with sodium ions and shows diuretic action. Spironolactone for Pharmacology Research CAS No. 58-93-5 C7H8ClN3O4S2=297.74 [Assay] 98.0+% (HPLC) [Soluble in] Acetone [Intended Purpose (Potency)] The product is a thiazide diuretic agent. It inhibits reabsorption of sodium and chloride ions and shows a diuretic effect. 191-16871 1g 197-16873 5g CAS No. 52-01-7 C24H32O4S=416.57 [Assay] 98.0+% (HPLC) [Soluble in] Methanol [Intended Purpose (Potency)] The product is an aldosterone antagonist. It competes with aldosterone, promotes sodium excretion, and inhibits the sodiumpotassium ion exchange reaction. n Choleretic Agents Product Name Ursodeoxycholic Acid Wako Cat. No. 357-25861 355-25862 Pkg. Size 5g 25g Product Name Anetholtrithion for Pharmacology Research CAS No. 128-13-2 C24H40O4=392.57 [Assay] 97.0+% [Soluble in] Ethanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] It shows a choleretic effect. Wako Cat. No. 015-21311 013-21312 Pkg. Size 5g 25g CAS No. 532-11-6 C10H8OS3=240.36 [Assay] 98.0+% (HPLC) [Soluble in] Chloroform [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] It is cholinergic and shows a sialagogic effect. n Anti-Osteoporosis Agents Product Name Ipriflavone for Biochemistry Wako Cat. No. 093-04911 Pkg. Size 500mg Product Name Risedronate Sodium Salt n -Hydrate for Pharmacology Research CAS No. 35212-22-7 C18H16O3=280.32 [Assay] 97.0+% (HPLC) [Soluble in] Methanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] It shows a direct inhibitory effect on bone resorption and promotes calcitonin secretion of estrogen. Alendronate Sodium Salt Trihydrate for Pharmacology Research 012-22661 100mg 018-22663 500mg Wako Cat. No. 189-02461 185-02463 Pkg. Size 100mg 500mg CAS No. 115436-72-1 C7H10NNaO7P2 · nH2O (C7H10NNaO7P2=305.09) [Assay] 97.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] The product is a bisphosphonate compound. It is preferentially distributed in the bone calcification site, to which osteoclasts attach, and inhibits bone resorption. CAS No. 121268-17-5 C4H12NNaO7P2 · 3H2O=325.12 [Assay] 97.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] The product is a bisphosphonate compound. It shows an inhibitory action on bone resorption. ● If no storage conditions are specified, store at room temperature. ● Bulk quote requests for some products are welcomed. Please contuct us. ● Listed products are intended for laboratory research use only, and not to be used for drug, food or human use. 23 6 n Anti-Pancreatitis Agents Product Name Gabexate Mesilate for Biochemistry Wako Cat. No. 078-03381 Pkg. Size 1g CAS No. 56974-61-9 C16H23N3O4 · CH3SO3H=417.48 [Assay] 98.0+% (HPLC) [Soluble in] Water [Intended Purpose (Potency)] The product is a pancreatic enzyme inhibitor. It shows an inhibitory action on proteases such as thrombin, trypsin, and kallikrein. n Antirheumatic Agents Product Name D (−)-Penicillamine Wako Special Grade Wako Cat. No. 161-18671 169-18672 Pkg. Size 5g 25g Actarit Product Name for Biochemistry CAS No. 52-67-5 C5H11NO2S=149.21 [Assay] 98.5+% (Titration) [Soluble in] Sodium hydroxide solution [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] Since it has a SH group, it has an ability to chelate heavy metals. It also cleaves a disulfide bond in immune complex molecules. 6 Auranofin for Biochemistry 012-25081 10mg 018-25083 100mg Wako Cat. No. 011-24451 017-24453 Pkg. Size 10mg 50mg CAS No. 18699-02-0 C10H11NO3=193.20 [Assay] 90.0+% (HPLC) [Soluble in] Methanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] It has a differentiation-inducing activity on suppressor T lymphocytes from the thymus gland. It shows the immune response, that is, production of suppressing factors from the T lymphocytes. CAS No. 34031-32-8 C20H34AuO9PS=678.48 [Assay] 90.0+% (HPLC) [Soluble in] Acetonitrile [Intended Purpose (Potency)] It shows autoantibody production and inhibitory effects on the function of inflammatory cells. n Antidotes Product Name Glutathione (Reduced Form) Wako Special Grade Wako Cat. No. 077-02011 073-02013 071-02014 077-02016 Pkg. Size 1g 5g 50g 100g CAS No. 70-18-8 C10H17N3O6S=307.33 [Assay] 97.0+% (Titration) (after drying) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] It involves with improvement of a variety of conjugated detoxification and shows an antidotal action. 24 Active Pharmaceutical Ingredients -Catalog- Product Name Glutathione, Oxidized Form for Biochemistry Wako Cat. No. 073-03331 079-03333 077-03334 Pkg. Size 250mg 1g 5g CAS No. 27025-41-8 C20H32N6O12S2=612.63 [Assay] 95.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] It involves with improvement of a variety of conjugated detoxification and shows an antidotal action. Please visit the Wako Online Catalog: http://www.e-reagent.com 7. Agents Acting on Urinary and Reproductive Systems n Urinary Organ/Genital Organ Agents Product Name Flavoxate Hydrochloride Wako Cat. No. for Biochemistry 063-02431 061-02432 Pkg. Size 5g 25g Product Name Hexamethylenetetramine JIS Special Grade CAS No. 3717-88-2 C24H25NO4 · HCl=427.93 [Assay] 99.0+% (Titration) [Soluble in] Water [Intended Purpose (Potency)] It shows inhibitory effects on contraction in the bladder smooth muscle. Ritodrine Hydrochloride (mixture of isomers) 186-02231 for Pharmacology Research 500mg Wako Cat. No. 081-00332 085-00335 Pkg. Size 25g 500g CAS No. 100-97-0 C6H12N4=140.19 [Assay] 99.0+% (Titration) [Soluble in] Water [Intended Purpose (Potency)] It has been said to show an antibacterial activity in the urinary organ system. Sildenafil Citrate for Biochemistry 192-16683 250mg 196-16681 1g CAS No. 171599-83-0 C22H30N6O4S · C6H8O7=666.70 [Assay] 90.0+% (HPLC) [Soluble in] DMSO [Intended Purpose (Potency)] It shows an inhibitory action on the activity of phosphodiesterase-5 (PDE-5). CAS No. 23239-51-2 C17H21NO3 · HCl=323.81 [Assay] 98.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] The product is a smooth muscle relaxant and has a uterine-relaxing action and shows an abortion preventive effect. 7 8 8. Agents Acting on Blood and Body Fluid n Anticoagulant Agents Product Name Heparin Sodium Wako Special Grade — Wako Cat. No. 085-00134 081-00136 081-00131 087-00133 Pkg. Size 10,000units 100,000units 1,000,000units 4,000,000units Product Name Warfarin Sodium for Biochemistry CAS No. 9041-08-1 [Activity] 130+ units/mg [Soluble in] Water [Intended Purpose (Potency)] It binds to antithrombin III and inhibits the thrombin action of that and shows an anticoagulant effect. Wako Cat. No. Pkg. Size 239-02171 10g 237-02172 25g CAS No. 129-06-6 C19H15NaO4=330.31 [Assay] 97.0+% (HPLC) [Soluble in] Ethanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] It competes with vitamin K and shows an anticoagulant effect. n Thrombolytic Agents Product Name Plasminogen, from Human Plasma for Cellbiology — Wako Cat. No. 164-24271 Pkg. Size 1mg CAS No. 9001-91-6 [Activity] 80+ units/mg [Storage condition] Keep at -80℃. [Intended Purpose (Potency)] The product is a precursor of the fibrinolysin, plasmin with molar weight of 90,000 to 92,000. It is hydrolyzed to plasmin by an urokinase (u-PA) or a tissue plasminogen activator (t-PA). ● If no storage conditions are specified, store at room temperature. ● Bulk quote requests for some products are welcomed. Please contuct us. ● Listed products are intended for laboratory research use only, and not to be used for drug, food or human use. 25 n Antiplatelet Agents Product Name Ticlopidine Hydrochloride Wako Cat. No. for Biochemistry 208-13971 206-13972 Pkg. Size 5g 25g Product Name Cilostazol for Pharmacology Research CAS No. 53885-35-1 C14H14ClNS · HCl=300.25 [Assay] 98.0+% (Titration) [Soluble in] Ethanol [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] It activates adenylyl cyclases and shows a platelet anti-aggregating effect. Clopidogrel Sulfate for Biochemistry 039-22651 250mg 035-22653 1g Wako Cat. No. 038-20661 034-20663 Pkg. Size 5g 100g CAS No. 73963-72-1 C20H27N5O2=369.46 [Assay] 98.0+% (HPLC) [Soluble in] Methanol [Intended Purpose (Potency)] It selectively inhibits phosphodiesterase III and shows a platelet anti-aggregating effect. CAS No. 120202-66-6 C16H16ClNO2S · H2SO4=419.90 [Assay] 90.0+% (HPLC) [Soluble in] Methanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] It inhibits ADP receptors and shows a platelet anti-aggregating effect. n Antithrombin Agents 8 Product Name Nafamostat Mesylate for Pharmacology Research Wako Cat. No. 141-08701 Pkg. Size 100mg Product Name Gabexate Mesilate for Biochemistry CAS No. 82956-11-4 C19H17N5O2 · 2CH3SO3H=539.58 [Assay] 98.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] The product is a synthetic antithrombotic agent. It inhibits serine proteases and shows an inhibitory action on blood coagulation. Wako Cat. No. 078-03381 Pkg. Size 1g CAS No. 56974-61-9 C17H27N3O7S=417.48 [Assay] 98.0+% (HPLC) [Soluble in] Water [Intended Purpose (Potency)] The product is a synthetic antithrombotic compound. It inhibits serine proteases and shows an inhibitory action on blood coagulation. n Hemostatic Agents Product Name trans -4-Aminomethyl-1cyclohexanecarboxylic Acid (Tranexamic Acid) Wako Special Grade Wako Cat. No. Pkg. Size 018-10931 5g 016-10932 25g CAS No. 1197-18-8 C8H15NO2=157.21 [Assay] 98.0+% (Titration) [Soluble in] Water [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] The product is an antiplasmin agent. It inhibits plasmin binding to fibrin and shows an inhibitory action on fibrin degradation. Carbazochrome Sodium Sulfonate Trihydrate for Biochemistry 030-13651 5g 038-13652 25g Product Name Thrombin, Type 2, Human Plasma for Biochemistry — Wako Cat. No. 209-13901 205-13903 Pkg. Size 100units 1,000units CAS No. 9002-04-4 [Soluble in] Water [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] It is an endoprotease relates to blood coagulation. It works on fibrinogen and shows an effect on fibrinogenesis. CAS No. 51460-26-5 C10H11N4NaO5S · 3H2O=376.32 [Assay] 99.0+% (HPLC) [Soluble in] Water [Intended Purpose (Potency)] It increases capillary resistance. 26 Active Pharmaceutical Ingredients -Catalog- Please visit the Wako Online Catalog: http://www.e-reagent.com 9. Anti-Inflammatory Agents n Nonsteroidal Anti-Inflammatory Agents n Salicylic acid compounds Product Name Acetylsalicylic Acid Wako Special Grade Wako Cat. No. 015-10262 017-10261 019-10265 Pkg. Size 25g 100g 500g CAS No. 50-78-2 C9H8O4=180.16 [Assay] 99.5+% (Titration) (after drying) [Soluble in] Ethanol, sodium carbonate solution [Intended Purpose (Potency)] The product is a salicylic acid compound. It selectively inhibits cyclooxygenase I (COX-I). n Acetic acid compounds Product Name Indomethacin for Biochemistry Wako Cat. No. 093-02473 097-02471 095-02472 Pkg. Size 5g 10g 25g 055-06971 10g 051-06973 50g Product Name Diclofenac Sodium for Biochemistry for Biochemistry 043-22851 Pkg. Size 10g CAS No. 15307-79-6 C14H10Cl2NNaO2=381.13 [Assay] 98.0+% (Titration) [Soluble in] Methanol [Intended Purpose (Potency)] The product is a phenylacetic acid compounds. It inhibits cyclooxygenase (COX) and shows an inhibitory action on prostaglandin biosynthesis. CAS No. 53-86-1 C19H16ClNO4=357.81 [Assay] 98.0+% (Titration) [Soluble in] Methanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] The product is an indoleacetic acid compounds. It selectively inhibits cyclooxygenase I. Etodolac Wako Cat. No. 9 CAS No. 41340-25-4 C17H21NO3=287.35 [Assay] 97.0+% (HPLC) [Soluble in] Methanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] The product is an indoleacetic acid compounds. It selectively inhibits cyclooxygenase-II. n Propionic acid compounds Product Name Ketoprofen for Biochemistry Wako Cat. No. 115-00381 113-00382 Pkg. Size 5g 25g Product Name Loxoprofen Sodium Salt Dihydrate for Pharmacology Research CAS No. 22071-15-4 C16H14O3=254.28 [Assay] 98.0+% (Titration) [Soluble in] Methanol [Intended Purpose (Potency)] The product is a propionic acid compound. It inhibits cyclooxygenase (COX) and shows an inhibitory action on prostaglandin biosynthesis. Ibuprofen for Biochemistry 098-02641 1g 094-02643 10g for Pharmacology Research 156-02711 5g 154-02712 25g 120-05511 128-05512 Pkg. Size 1g 25g CAS No. 80382-23-6 C15H17NaO3 · 2H2O=304.31 [Assay] 98.0+% (Titration) (calculated on the anhydrous basis) [Soluble in] Water [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] The product is a propionic acid compound. It inhibits cyclooxygenase (COX) and shows an inhibitory action on prostaglandin biosynthesis. Pranoprofen (mixture of isomers) for Pharmacology Research CAS No. 15687-27-1 C13H18O2=206.28 [Assay] 98.5+% (Titration) [Soluble in] Ethanol, Sodium hydroxide solution [Intended Purpose (Potency)] The product is a propionic acid compound. It inhibits cyclooxygenase (COX) and shows an inhibitory action on prostaglandin biosynthesis. Oxaprozin Wako Cat. No. 161-23441 5g 167-23443 100g CAS No. 52549-17-4 C15H13NO3=255.27 [Assay] 98.0+% (HPLC) [Soluble in] N,N -Dimethylformamide [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] The product is a propionic acid compound. It inhibits cyclooxygenase (COX) and shows an inhibitory action on prostaglandin biosynthesis. CAS No. 21256-18-8 C18H15NO3=293.32 [Assay] 98.0+% [Soluble in] Methanol [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] The product is a propionic acid compound. It inhibits cyclooxygenase (COX) and shows an inhibitory action on prostaglandin biosynthesis. ● If no storage conditions are specified, store at room temperature. ● Bulk quote requests for some products are welcomed. Please contuct us. ● Listed products are intended for laboratory research use only, and not to be used for drug, food or human use. 27 n Oxicam compounds Product Name Piroxicam for Biochemistry Wako Cat. No. 162-20291 168-20293 166-20294 Pkg. Size 1g 5g 10g Product Name Meloxicam for Biochemistry for Pharmacology Research 017-21491 1g 013-21493 5g Pkg. Size 136-14181 200mg 132-14183 1g CAS No. 71125-38-7 C14H13N3O4S2=351.40 [Assay] 98.0+% (Titration) [Soluble in] N,N -Dimethylformamide [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] The product is an oxicam compound. It selectively inhibits cyclooxygenase II (COX-II) and shows an inhibitory action on prostaglandin biosynthesis. CAS No. 36322-90-4 C15H13N3O4S=331.35 [Assay] 97.0+% (HPLC) [Soluble in] Acetone [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] The product is an oxicam compound. It inhibits cyclooxygenase (COX) and shows an inhibitory action on prostaglandin biosynthesis. Ampiroxicam Wako Cat. No. CAS No. 99464-64-9 C20H21N3O7S=447.46 [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] The product is an oxicam compound. It inhibits cyclooxygenase (COX) and shows an inhibitory action on prostaglandin biosynthesis. n Other Anti-Inflammatory Agents Product Name Glycyrrhizin 9 for Biochemistry Wako Cat. No. 074-03481 Pkg. Size 100mg Product Name Bromelain CAS No. 1405-86-3 C42H62O16=822.93 [Assay] 90.0+% (HPLC) [Soluble in] Methanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] It is an active ingredient of licorice. It is a kind of corticosteroid. It is said to show an aldosterone-like action. 10 Guaiazulene 320-20571 10g 328-20572 25g — Wako Cat. No. 022-04261 020-04262 Pkg. Size 5g 25g CAS No. 37189-34-7 [Activity] 800+units/mg [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] It is a kind of protease. It exists in fruits and leaves of pineapples. Bromelain nonspecifically breaks down various kinds of peptide bonds. CAS No. 489-84-9 C15H18=198.31 [Assay] 96.0+% [Intended Purpose (Potency)] It shows an anti-inflammatory effect and an anti-allergic effect. 10. Anti-Allergic and Antihistamine Agents n Antiallergic Agents Product Name Sodium Cromoglicate for Pharmacology Research Wako Cat. No. 193-15231 199-15233 Pkg. Size 1g 5g CAS No. 15826-37-6 C23H14O11Na2=512.33 [Assay] 98.0+% (calculated on the anhydrous basis) [Soluble in] Water [Intended Purpose (Potency)] This product inhibits the release of chemical mediators. 28 Active Pharmaceutical Ingredients -Catalog- Tranilast Product Name for Pharmacology Research Wako Cat. No. 203-18301 Pkg. Size 10mg CAS No. 53902-12-8 C18H17NO5=327.33 [Assay] 98.0+% (HPLC) [Soluble in] Ethanol [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] This product inhibits the release of chemical mediators. Please visit the Wako Online Catalog: http://www.e-reagent.com n Antihistamines Product Name Ketotifen Fumarate for Biochemistry Wako Cat. No. 111-00621 115-00624 117-00623 Pkg. Size 200mg 1g 5g Product Name Emedastine Difumarate for Biochemistry for Biochemistry 037-13801 500mg Promethazine Hydrochloride for Biochemistry for Biochemistry 030-13271 5g 038-13272 25g Ebastine for Biochemistry for Biochemistry 046-19771 5g 044-19772 25g 10mg 054-08543 50mg 160-11642 25g 050-08621 100mg 056-08623 500mg CAS No. 90729-43-4 C32H39NO2=469.66 [Assay] 90.0+% (HPLC) [Soluble in] Methanol [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] It acts as an antihistamine. CAS No. 2438-32-6 C16H19ClN2 · C4H4O4=390.86 [Assay] 99.0+% (Titration) (after drying) [Soluble in] Water [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] This product is an alkylamine derivative. This product is an antihistamine and an inhibitor of chemical mediator release. Diphenhydramine Hydrochloride CAS No. 58-33-3 C17H20N2S · HCl=320.88 [Assay] 98.0+% (Titration) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is a phenothiazine derivative. It acts as an antihistamine. CAS No. 14976-57-9 C21H26ClNO · C4H4O4=459.97 [Assay] 98.0+% (Titration) [Soluble in] Methanol [Intended Purpose (Potency)] This product is a propanolamine derivative. It acts as an antihistamine. (+)-Chlorpheniramine Maleate Pkg. Size 058-08541 CAS No. 87233-62-3 C17H26N4O · 2C4H4O4=534.56 [Assay] 90.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] It acts as an antihistamine. CAS No. 34580-14-8 C23H23NO5S=425.50 [Assay] 98.0+% (Titration) [Soluble in] Methanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is an antihistamine and an inhibitor of chemical mediator release. Clemastine Fumarate Wako Cat. No. Epinastine Hydrochloride for Biochemistry 059-08571 10mg 055-08573 50mg 10 CAS No. 108929-04-0 C16H15N3 · HCl=285.77 [Assay] 90.0+% (HPLC) [Soluble in] Water [Intended Purpose (Potency)] It acts as an antihistamine. CAS No. 147-24-0 C17H21NO · HCl=291.82 [Assay] 98.0+% (Titration) [Soluble in] Water, Ethanol [Intended Purpose (Potency)] This product is a diphenhydramine derivative. This product is an antihistamine and an inhibitor of chemical mediator release. n Antileukotriene Agents Ibudilast Product Name for Pharmacology Research Wako Cat. No. 096-06101 092-06103 Pkg. Size 10mg 50mg Product Name Montelukast Sodium Salt for Biochemistry CAS No. 50847-11-5 C14H18N2O=230.31 [Assay] 98.0+% (HPLC) [Soluble in] Ethanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] It inhibits release of leukotrienes C4 and B4 and exhibits antagonistic activity against leukotrienes and PAF. It is used as therapeutic medicine for bronchial asthma. Wako Cat. No. 133-17371 139-17373 Pkg. Size 100mg 500mg CAS No. 151767-02-1 C35H35ClNNaO3S=608.17 [Assay] 90.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] Leukotriene receptor inhibitor. It is an anti-inflammatory agent that suppresses bronchoconstriction. n Other Antiallergic and Antihistamine Agents Product Name Suplatast Tosylate for Biochemistry Wako Cat. No. 198-16881 194-16883 Pkg. Size 250mg 1g Actarit Product Name for Biochemistry CAS No. 94055-76-2 C16H26NO4S · C7H7O3S=499.64 [Assay] 90.0+% (HPLC) [Soluble in] Water [Intended Purpose (Potency)] It is a Th2 cytokine inhibitor which inhibits the production of interleukins 2, 5 and 13. It can also regulate the immune reaction by suppressing the IgE production, eosinophil infiltration and histamine release. ● If no storage conditions are specified, store at room temperature. ● Bulk quote requests for some products are welcomed. Please contuct us. ● Listed products are intended for laboratory research use only, and not to be used for drug, food or human use. Wako Cat. No. 011-24451 017-24453 Pkg. Size 10mg 50mg CAS No. 18699-02-0 C10H11NO3=193.20 [Assay] 90.0+% (HPLC) [Soluble in] Methanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] It is considered to be effective for rheumatoid arthritis by the induction of differentiation of suppressor T-lymphocytes from the thymus, by increase in T-lymphocyte number due to the enhanced production of interleukin-2, and by the immune response reaction of production of the suppressive factor by the activated T-lymphocytes. 29 11. Hormonal Agents n Corticosteroids Product Name Dexamethasone Dipropionate for Pharmacology Research Wako Cat. No. 044-30571 040-30573 Pkg. Size 1g 5g Product Name Betamethasone for Biochemistry Wako Special Grade 082-02481 088-02483 086-02484 100mg 1g 5g Beclomethasone Dipropionate for Pharmacology Research for Biochemistry 080-05581 1g 086-05583 5g Betamethasone Sodium Phosphate for Pharmacology Research 11 for Pharmacology Research 081-09911 1g 087-09913 5g Betamethasone Dipropionate for Biochemistry for Biochemistry 165-11491 1g 161-11493 5g Betamethasone Valerate for Biochemistry for Biochemistry 163-14591 5g CAS No. 2920-86-7 C25H32O8=460.52 [Assay] 98.0+% (HPLC) [Soluble in] Methanol [Intended Purpose (Potency)] This product is a corticosteroid. It has glucocorticoid activity enhanced by the introduction of a double bond. It has attenuated mineralcorticoid activity. 30 Active Pharmaceutical Ingredients -Catalog- 1g 5g 027-17641 250mg 023-17643 1g 029-18181 1g 028-10091 1g 024-10093 5g 021-10101 1g 027-10103 5g CAS No. 2152-44-5 C27H37FO6=476.58 [Assay] 97.0+% (HPLC) [Soluble in] 1,4-Dioxane [Intended Purpose (Potency)] This product is a corticosteroid. It suppresses electrolyte activity by the addition of a methyl group at the 16α position of glucocorticoid. It has attenuated mineralcorticoid activity. CAS No. 50-24-8 C21H28O5=360.44 [Assay] 97.0 - 103.0% (molecular absorptiometric analysis) [Soluble in] Ethanol [Intended Purpose (Potency)] This product is a corticosteroid. It has glucocorticoid activity enhanced by the introduction of a double bond. It has attenuated mineralcorticoid activity. Prednisolone Succinate CAS No. 5593-20-4 C28H37FO7=504.59 [Assay] 97.0+% (HPLC) 97+% (TLC) [Soluble in] 1,4-Dioxane [Intended Purpose (Potency)] This product is a corticosteroid. It suppresses electrolyte activity by the addition of a methyl group at the 16α position of glucocorticoid. It has attenuated mineralcorticoid activity. CAS No. 50-03-3 C23H32O6=404.50 [Assay] 97.0+% (HPLC) [Soluble in] Ethanol [Intended Purpose (Potency)] This product is a corticosteroid. Prednisolone 027-10083 Pkg. Size CAS No. 151-73-5 C22H28FNa2O8P=516.40 [Assay] 96.0+% (HPLC) [Soluble in] Water [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] This product is a corticosteroid. It suppresses electrolyte activity by the addition of a methyl group at the 16α position of glucocorticoid. It has attenuated mineralcorticoid activity. CAS No. 2203-97-6 C25H34O8=462.53 [Assay] 98.0+% (HPLC) [Soluble in] Ethanol [Intended Purpose (Potency)] This product is a corticosteroid. Hydrocortisone Acetate CAS No. 5534-09-8 C28H37ClO7=521.04 [Assay] 97.0+% (HPLC) [Soluble in] Ethanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is a corticosteroid. It has attenuated mineralcorticoid activity. CAS No. 50-23-7 C21H30O5=362.47 [Assay] 97.0 - 102.0+% (HPLC) [Soluble in] Methanol, Acetone [Intended Purpose (Potency)] This product is a corticosteroid. Hydrocortisone Succinate 021-10081 CAS No. 378-44-9 C22H29FO5=392.46 [Assay] 96.0+% (HPLC) [Soluble in] 1,4-Dioxane [Intended Purpose (Potency)] This product is a corticosteroid. A methyl group is adducted at the 16α position of glucocorticoid. It has attenuated mineralcorticoid activity. CAS No. 55541-30-5 C28H37FO7=504.59 [Assay] 97.0+% (HPLC) [Soluble in] Methanol [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] This product is a corticosteroid. Hydrocortisone Wako Cat. No. Dexamethasone for Biochemistry 047-18863 100mg 041-18861 1g CAS No. 50-02-2 C22H29FO5=392.47 [Assay] 98.0 - 102.0% [Soluble in] Methanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is a corticosteroid. A methyl group is adducted at the 16β position of glucocorticoid. It has attenuated mineralcorticoid activity. Please visit the Wako Online Catalog: http://www.e-reagent.com Product Name Dexamethasone Sodium Phosphate for Pharmacology Research Wako Cat. No. 040-30811 046-30813 Pkg. Size 250mg 1g Product Name Fluorometholone for Biochemistry CAS No. 2392-39-4 C22H28FNa2O8P=516.40 [Assay] 97.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is a corticosteroid. A methyl group is adducted at the 16β position of glucocorticoid. It has attenuated mineralcorticoid activity. Clobetasol Propionate for Biochemistry 031-19661 500mg 037-19663 1g Wako Cat. No. 067-02451 063-02453 Pkg. Size 250mg 1g CAS No. 426-13-1 C22H29FO4=376.46 [Assay] 98.0+% (HPLC) [Soluble in] Ethanol [Intended Purpose (Potency)] This product is a corticosteroid. It has attenuated mineralcorticoid activity. Triamcinolone Acetonide for Biochemistry CAS No. 25122-46-7 C25H32ClFO5=466.97 [Soluble in] 1,4-Dioxane [Intended Purpose (Potency)] This product is a corticosteroid. It has attenuated mineralcorticoid activity. 209-10961 1g 205-10963 5g CAS No. 76-25-5 C24H31FO6=434.50 [Assay] 98.0+% (HPLC) [Soluble in] Ethanol [Intended Purpose (Potency)] This product is a corticosteroid. It has glucocorticoid activity enhanced by the addition of fluorine. n Sex Hormones Product Name Medroxyprogesterone Acetate for Biochemistry Wako Cat. No. 138-09991 134-09993 Pkg. Size 1g 5g CAS No. 71-58-9 C24H34O4=386.53 [Assay] 98.0+% (HPLC) [Soluble in] 1,4-Dioxane [Intended Purpose (Potency)] Progestational agent Allylestrenol for Pharmacology Research 016-21221 Product Name β-Estradiol for Biochemistry for Biochemistry 500mg Testosterone Enanthate for Cellbiology for Biochemistry 054-08521 1g 050-08523 5g Nandrolone Decanoate for Biochemistry 085-09811 10g 081-09813 50g for Biochemistry 035-15161 1g 031-15163 5g 200-17951 5g 208-17952 25g 11 145-09181 1g 141-09183 5g CAS No. 360-70-3 C28H44O3=428.65 [Assay] 90.0+% (HPLC) [Soluble in] Ethanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is a long-acting anabolic steroid. It exhibits anabolism. Danazol for Biochemistry CAS No. 630-56-8 C27H40O4=428.60 [Assay] 97.0+% (HPLC) [Soluble in] Methanol [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] Progestational agent Chlormadinone Acetate Pkg. Size 250mg 1g 5g CAS No. 315-37-7 C26H40O3=400.59 [Assay] 97.0+% (HPLC) [Soluble in] Ethanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is a long-acting synthetic testosterone. It is a compound longeracting with testosterone enanthate. It acts as a testosterone by hydrolysis in the body. CAS No. 979-32-8 C23H32O3=356.50 [Assay] 90.0+% (HPLC) [Soluble in] Ethanol [Intended Purpose (Potency)] This product is an estrogen preparation. Hydroxyprogesterone Caproate CAS No. 50-28-2 C18H24O2=272.39 [Assay] 97.0 - 103.0% (after drying) [Soluble in] Acetone [Intended Purpose (Potency)] Progestational agent CAS No. 432-60-0 C21H32O=300.48 [Assay] 97.0+% (HPLC) [Soluble in] Ethanol [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] Progestational agent. This product acts as a progestogen and an androgen. Estradiol Valerate Wako Cat. No. 056-04044 052-04041 058-04043 040-32631 250mg 046-32633 2g CAS No. 17230-88-5 C22H27NO2=337.46 [Assay] 90.0+% (HPLC) [Soluble in] Methanol [Intended Purpose (Potency)] This product is a testosterone derivative. It suppresses gonadotropin secretion from the pituitary gland and decreases estrogen production in the ovaries. CAS No. 302-22-7 C23H29ClO4=404.93 [Assay] 98.0+% (HPLC) [Soluble in] Acetonitrile [Intended Purpose (Potency)] Progestational agent ● If no storage conditions are specified, store at room temperature. ● Bulk quote requests for some products are welcomed. Please contuct us. ● Listed products are intended for laboratory research use only, and not to be used for drug, food or human use. 31 n Thyroid Hormone Derivatives Product Name Thyrotropin Releasing Hormone for Biochemistry — n Growth Hormones Wako Cat. No. 200-07941 Pkg. Size 1mg Product Name Growth Hormone, Human, recombinant for Biochemistry CAS No. 24305-27-9 C16H22N6O4 · C4H6O6 · H2O=362.39 [Assay] 98.5+ % (Titration) (calculated on the dehydrous basis) [Soluble in] Water [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] Thyroid-stimulating-hormone (TSH) releasing hormone. It stimulates secretion of TSH and also of prolactin. — Wako Cat. No. Pkg. Size 071-04591 1mg 077-04593 5mg CAS No. 12629-01-5 [Soluble in] Water [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] Human growth hormone (hGH, also known as somatropin) is a polypeptide with 191 amino acid residues and molecular weight of approximately 22 kDa. It promotes growth and gluconeogenesis. n Hypothalamus Hormones Product Name Buserelin Acetate for Biochemistry — Wako Cat. No. 026-17851 022-17853 Pkg. Size 50mg 200mg CAS No. 68630-75-1 C60H86N16O13 · C2H4O2=1299.48 [Assay] 98.0+%(HPLC) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is a derivative compound of gonadotropin-releasing hormone (Gn-RH). Repeated administration of the product enables suppression of gonadotropin and sex hormone secretion. Product Name Nafarelin Acetate n -Hydrate for Biochemistry — Wako Cat. No. 149-09221 145-09223 Pkg. Size 1mg 10mg CAS No. 86220-42-0 C66H83N17O13 · xC2H4O2 · nH2O (C66H83N17O13=1322.47) [Assay] 90.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] This product is a derivative of gonadotropin-releasing hormone (Gn-RH). It is a compound with higher affinity to Gn-RH receptors and is long-acting with increased biological activity. 11 32 Active Pharmaceutical Ingredients -Catalog- Please visit the Wako Online Catalog: http://www.e-reagent.com 12. Ophthalmic Agents n Antiglaucoma Agents Product Name Wako Cat. No. (±)-Betaxolol Hydrochloride for Pharmacology Research 025-16101 023-16102 Pkg. Size 1g 25g Product Name Latanoprost for Biochemistry CAS No. 63659-19-8 C18H29NO3 · HCl=343.89 [Assay] 97.0+% [Soluble in] Water [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] This product acts as a β1 blocker. Timolol Maleate for Pharmacology Research 206-19491 100mg 202-19493 1g Wako Cat. No. 129-06201 125-06203 Pkg. Size 10mg 50mg CAS No. 130209-82-4 C26H40O5=432.59 [Assay] 90.0+% (HPLC) [Soluble in] Acetonitrile [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] This product is a PGF2α derivative. It acts as a prostaglandin. CAS No. 26921-17-5 C13H24N4O3S · C4H4O4=432.49 [Assay] 98.0+% (HPLC) [Soluble in] Water [Intended Purpose (Potency)] This product acts as a β blocker. n Anticataract Agents Product Name Pirenoxine for Biochemistry Wako Cat. No. 163-25721 169-25723 Pkg. Size 10mg 100mg CAS No. 1043-21-6 C16H8N2O5=308.25 [Assay] 90.0+% (HPLC) [Soluble in] Phosphate buffer solution [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] This product competitively inhibits quinoids from binding to water-soluble protein and prevents lens opacity. 12 n Mydriatics Product Name Atropine Sulfate Monohydrate Wako Special Grade Wako Cat. No. 019-04851 015-04853 013-04854 Pkg. Size 1g 5g 10g Product Name Wako Cat. No. (R )-(-)-Phenylephrine Hydrochloride 163-11791 for Biochemistry CAS No. 5908-99-6 (C17H23NO3) 2 · H2SO4 · H2O=694.83 [Assay] 98.0+ % (as an anhydride) (Titration) (after drying) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product acts as a competitive antagonist to acetylcholine at muscarinic receptors. ● If no storage conditions are specified, store at room temperature. ● Bulk quote requests for some products are welcomed. Please contuct us. ● Listed products are intended for laboratory research use only, and not to be used for drug, food or human use. Pkg. Size 5g CAS No. 61-76-7 C9H13NO2 · HCl=203.67 [Assay] 98.0+% (Titration) [Soluble in] Water [Intended Purpose (Potency)] This product acts as an adrenergic receptor (α1) agonist. 33 13. Antibiotics n Penicillin Antibiotics Product Name Wako Cat. No. 016-23301 012-23303 014-23302 Ampicillin Sodium for Biochemistry Pkg. Size 5g 10g 25g Product Name Benzylpenicillin Potassium for Biochemistry for Biochemistry 017-14161 5g 015-14162 25g Oxacillin Sodium Monohydrate for Biochemistry CAS No. 61336-70-7 C16H19N3O5S · 3H2O=419.46 [Assay] 95.0+% (Titration) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] Penicillin antibiotic with inhibitory effect on cell wall biosynthesis. This product is a narrow-spectrum antibiotic, but is active against Gramnegative and Gram-positive bacteria. 024-18131 022-18132 020-18133 Benzylpenicillin Sodium Salt for Biochemistry Pkg. Size 023-07731 5g 021-07732 25g CAS No. 113-98-4 C16H17KN2O4S=372.48 [Potency]1430+units/mg [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] Penicillin antibiotic with inhibitory effect on cell wall biosynthesis CAS No. 69-52-3 C16H18N3NaO4S=371.39 [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] Penicillin antibiotic with inhibitory effect on cell wall biosynthesis. This product is a narrow-spectrum antibiotic, but is active against Gramnegative and Gram-positive bacteria. Amoxicillin Trihydrate Wako Cat. No. 154-02131 150-02133 158-02134 1g 5g 10g CAS No. 7240-38-2 C19H18N3NaO5S · H2O=441.43 [Potency]815 - 950μg/mg [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] Penicillin antibiotic with inhibitory effect on cell wall biosynthesis. This product appears to be also effective against staphylococcus. 5g 25g 100g CAS No. 69-57-8 C16H17N2NaO4S=356.38 [Potency]1500 - 1750units/mg [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] Penicillin antibiotic with inhibitory effect on cell wall biosynthesis 13 n Cephem Antibiotics Product Name Cefalexin for Biochemistry Wako Cat. No. 036-11051 034-11052 Pkg. Size 5g 25g Product Name Cefazolin Sodium Salt for Biochemistry CAS No. 15686-71-2 C16H17N3O4S=347.39 [Potency]900+ μg/mg (calculated on the dehydrous basis) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is a first-generation cephalosporin antibiotic. It binds to penicillin-binding protein and inhibits cell wall synthesis. It is a narrowspectrum antibiotic, but is active against staphylococcus. Cefaclor Monohydrate for Pharmacology Research 034-20261 200mg CAS No. 70356-03-5 C15H14ClN3O4S · H2O=385.82 [Assay] 97.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is a first-generation cephalosporin antibiotic. It is active against bacteria by inhibiting bacterial cell wall synthesis. 34 Active Pharmaceutical Ingredients -Catalog- Wako Cat. No. 038-22981 034-22983 Pkg. Size 1g 5g CAS No. 27164-46-1 C14H13N8NaO4S3=476.49 [Assay] 90.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is a 1st-generation cephalosporin antibiotic. It binds to penicillin-binding protein and inhibits cell wall synthesis. It is a narrowspectrum antibiotic, but is active against staphylococcus. Cephalothin Sodium Salt for Biochemistry 037-22831 5g 035-22832 25g CAS No. 58-71-9 C16H15N2NaO6S2=418.42 [Assay] 90.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] A cephem antibiotic that belongs to the 1st-generation cephem. It binds to penicillin-binding protein and inhibits cell wall synthesis. It is a narrowspectrum antibiotic, but is active against staphylococcus. Please visit the Wako Online Catalog: http://www.e-reagent.com Cefdinir Product Name for Biochemistry Wako Cat. No. 037-22691 033-22693 Pkg. Size 250mg 1g Product Name Cefteram Pivoxil for Biochemistry CAS No. 91832-40-5 C14H13N5O5S2=395.41 [Assay] 90.0+% (HPLC) [Soluble in] Phosphate buffer solution [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] A 3rd generation cephalosporin. It binds to penicillin-binding protein and inhibits cell wall synthesis. It is a broad-spectrum antibiotic and is highly active against Gram-negative bacteria. Cefcapene Pivoxil Hydrochloride Hydrate for Biochemistry 037-22711 033-22713 100mg 500mg Wako Cat. No. 032-22761 038-22763 Pkg. Size 50mg 250mg CAS No. 82547-81-7 C22H27N9O7S2=593.64 [Assay] 90.0+% (HPLC) [Soluble in] Methanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] A 3rd generation cephalosporin. It binds to penicillin-binding protein and inhibits cell wall synthesis. It is a broad-spectrum antibiotic and is highly active against Gram-negative bacteria. Cefpirome Sulfate for Biochemistry 030-22701 5g 038-22702 25g CAS No. 98753-19-6 C22H22N6O5S2 · H2SO4=612.66 [Assay] 90.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] A 4th generation cephalosporin. It binds to penicillin-binding protein and inhibits cell wall synthesis. It is a broad-spectrum antibiotic and is highly active against Gram-negative bacteria. It is stable in the presence of β-lactamase. CAS No. 147816-24-8 C23H29N5O8S2 · HCl · H2O=622.11 [Assay] 90.0+% (HPLC) [Soluble in] Methanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] A 3rd generation cephalosporin. It binds to penicillin-binding protein and inhibits cell wall synthesis. It is a broad-spectrum antibiotic and is highly active against Gram-negative bacteria. n β-lactamase Inhibitors Product Name Sulbactam Sodium Salt for Biochemistry Wako Cat. No. 194-17081 192-17082 Pkg. Size 5g 25g CAS No. 69388-84-7 C8H10NNaO5S=255.22 [Assay] 90.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] A β-lactamase inhibitor. It has irreversibly inhibitory effect against the β-lactamase produced by various bacterias. n Carbapenem Antibiotics Product Name Meropenem Trihydrate for Genetic Research Wako Cat. No. 133-15671 139-15673 137-15674 Pkg. Size 1g 5g 10g Product Name Imipenem n-Hydrate for Cellbiology CAS No. 119478-56-7 C17H25N3O5S · 3H2O=437.51 [Assay] 98.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is a carbapenem antibiotic. It binds to penicillin-binding protein and inhibits cell wall synthesis. It is a broadspectrum antibiotic and is highly active against Pseudomonas aeruginosa. It is stable in the presence of β-lactamase. Cilastatin Sodium Salt for Cellbiology 031-19563 1g 035-19561 5g Wako Cat. No. Pkg. Size 090-06361 25mg 096-06363 100mg 13 CAS No. 74431-23-5 C12H17N3O4S · nH2O (C12H17N3O4S=299.35) [Assay] 98.0+% (HPLC) [Soluble in] Water [Intended Purpose (Potency)] This product is a carbapenem antibiotic. It binds to penicillin-binding protein and inhibits cell wall synthesis. It is a broadspectrum antibiotic and is highly active against Pseudomonas aeruginosa. It is stable in the presence of β-lactamase. CAS No. 81129-83-1 C16H25N2NaO5S=380.43 [Assay] 98.5+% (HPLC) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is a dehydropeptidase I inhibitor. It is used as an adjuvant of carbapenem antibiotics to inactivate these antibiotics by hydrolysis with dehydropeptidase I. ● If no storage conditions are specified, store at room temperature. ● Bulk quote requests for some products are welcomed. Please contuct us. ● Listed products are intended for laboratory research use only, and not to be used for drug, food or human use. 35 n Chloramphenicol Antibiotics Product Name Chloramphenicol for Biochemistry Wako Cat. No. 036-10571 034-10572 032-10573 Pkg. Size 5g 25g 100g CAS No. 56-75-7 C11H12Cl2N2O5=323.13 [Soluble in] Ethanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is a chloramphenicol antibiotic. It binds to the 50S subunit of bacterial ribosomes and inhibits protein synthesis. It is a broad-spectrum antibiotic and is active against multiple bacteria and rickettsiae. n Aminoglycoside Antibiotics Product Name Gentamicin Sulfate for Biochemistry Wako Cat. No. 073-02971 079-02973 077-02974 071-02972 Pkg. Size 250mg 1g 5g 25g Product Name Kanamycin Sulfate for Biochemistry 146-08871 for Cellbiology 50g CAS No. 1405-10-3 C23H46N6O13 · nH2SO4 (C23H46N6O13=614.64) [Potency] 680+ IU/mg (calculated on the dried basis) [Soluble in] Water [Intended Purpose (Potency)] Aminoglycoside Antibiotic. This product binds to the 30S subunit of bacterial ribosomes and inhibits protein synthesis. It is highly active against Gram-positive and Gram-negative bacteria. 13 Amikacin Sulfate for Biochemistry 014-24941 1g 010-24943 5g Pkg. Size 1g 5g 25g 100g CAS No. 25389-94-0 C18H36N4O11 · nH2SO4 (C18H36N4O11=484.50) [Potency] 600+ μg/mg (calculated on the dried basis) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] Aminoglycoside Antibiotic. This product binds to the 30S and 50S subunits of bacterial ribosomes, and inhibits protein synthesis. It is active against Gram-positive and Gram-negative bacteria. CAS No. 1405-41-0 [Potency (as gentamicin C1)] 590+ μg/mg (calculated on the dried basis) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] Aminoglycoside Antibiotic. This product binds to the 30S and 50S subunits of bacterial ribosomes, and inhibits protein synthesis. It is highly active against Grampositive and Gram-negative bacteria. Neomycin Sulfate Wako Cat. No. 117-00341 113-00343 115-00342 111-00344 Streptomycin Sulfate for Biochemistry 196-08511 194-08512 192-08513 198-08515 5g 25g 100g 500g CAS No. 3810-74-0 C21H39N7O12 · 1.5H2SO4=728.69 [Potency] 718+ μg/mg (calculated on the dried basis) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] Aminoglycoside Antibiotic. This product binds to the 30S subunit of bacterial ribosomes and inhibits protein synthesis. It is active against Grampositive and Gram-negative bacteria. Ribostamycin Sulfate for Genetic Research CAS No. 39831-55-5 C22H43N5O13 · 2H2SO4=781.76 [Potency] 674 - 786 IU/mg (calculated on the dried basis) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] Aminoglycoside Antibiotic. This product binds to the 30S subunit of bacterial ribosomes and inhibits protein synthesis. It is highly active against Pseudomonas aeruginosa. 187-02901 250mg 183-02903 1g CAS No. 53797-35-6 C17H34N4O10 · nH2SO4 (C17H34N4O10=454.47) [Potency] 680 - 780 μg/mg (calculated on the dried basis) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is an aminoglycoside antibiotic. It binds to the 30S subunit of bacterial ribosomes and inhibits protein synthesis. It is active against Grampositive and Gram-negative bacteria. n Macrolide Antibiotics Product Name Roxithromycin Wako 1st Grade Wako Cat. No. 183-02121 181-02122 Pkg. Size 5g 25g CAS No. 80214-83-1 C41H76N2O15=837.05 [Assay] 95.0+% (HPLC) [Soluble in] Ethanol [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] This product is a macrolide antibiotic. It binds to the 50S subunit of bacterial ribosomes and inhibits protein synthesis. It is active against Gram-positive and Gramnegative bacteria. 36 Active Pharmaceutical Ingredients -Catalog- Product Name Lincomycin Hydrochloride Monohydrate for Pharmacology Research Wako Cat. No. 122-05711 128-05713 Pkg. Size 1g 5g CAS No. 7179-49-9 C18H34N2O6S · HCl · H2O=461.01 [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is a macrolide antibiotic. It binds to the 50S subunit of bacterial ribosomes and inhibits protein synthesis. It is active against Gram-positive and Gramnegative bacteria. Please visit the Wako Online Catalog: http://www.e-reagent.com Product Name Erythromycin Wako Cat. No. 057-07151 055-07152 Pkg. Size 5g 25g CAS No. 114-07-8 C37H67NO13=733.93 [Soluble in] Ethanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is a macrolide antibiotic. It binds to the 50S subunit of bacterial ribosomes and inhibits protein synthesis. It is active against Gram-positive and Gramnegative bacteria. n Tetracycline Antibiotics Product Name Tetracycline Hydrochloride for Biochemistry Wako Cat. No. 205-08591 203-08592 201-08593 Pkg. Size 5g 25g 100g Product Name Minocycline Hydrochloride for Pharmacology Research Wako Cat. No. Pkg. Size 136-16401 200mg 132-16403 1g CAS No. 13614-98-7 C23H27N3O7 · HCl=493.94 [Potency] 890 - 950 μg/mg (calculated on the dehydrous basis) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is a tetracycline antibiotic. It binds to the 30S subunit of bacterial ribosomes and inhibits aminoacyl-tRNA from binding to the ribosomal A-site. It is a broad-spectrum antibiotic and is active against bacteria including mycoplasmas and chlamydiae. CAS No. 64-75-5 C22H24N2O8 · HCl=480.90 [Potency] 900+ μg/mg [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is a tetracycline antibiotic. It binds to the 30S subunit of bacterial ribosomes and inhibits aminoacyl-tRNA from binding to the ribosomal A-site. It is a broad-spectrum antibiotic and is active against bacteria including mycoplasmas and chlamydiae. n Other Antibiotics Product Name Rifampicin for Biochemistry Wako Cat. No. 189-01001 185-01003 Pkg. Size 1g 5g Product Name Fosfomycin Sodium for Pharmacology Research CAS No. 13292-46-1 C43H58N4O12=822.95 [Potency] 900+ μg/mg [Soluble in] Methanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product inhibits RNA synthesis by interfering with bacterial DNA-dependent RNA polymerase. Sulfamethoxazole for Biochemistry 199-10451 10g 195-10453 100g for Biochemistry 220-01304 226-01301 226-01306 222-01303 250mg 1g 5g 10g 069-05331 067-05332 Pkg. Size 5g 25g CAS No. 26016-99-9 C3H5Na2O4P=182.02 [Assay] 95.0+% (Titration) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is a fosfomycin antibiotic. It inhibits cell wall synthesis. It exhibits excellent antibacterial activity against Pseudomonas aeruginosa and Escherichia coli. Tigecycline for Biochemistry CAS No. 723-46-6 C10H11N3O3S=253.28 [Assay] 98.0+% (Titration) [Soluble in] Sodium hydroxide solution [Intended Purpose (Potency)] This product inhibits dihydrofolate synthesis by competing with paraaminobenzoic acid. Vancomycin Hydrochloride Wako Cat. No. 206-19631 100mg 202-19633 1g 13 CAS No. 220620-09-7 C29H39N5O8=585.65 [Assay] 90.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] It is a glycylcycline-type antibiotic that inhibits bacterial protein synthesis by binding to liposome 30S. Its binding sites are different from those tetracycline-type antibiotics bind to. Clindamycin Hydrochloride for Cellbiology CAS No. 1404-93-9 C66H75Cl2N9O24 · HCl=1485.71 [Potency (caluculated on the dehydrous basis)] 1,050+ IU/mg [Soluble in] Water [Intended Purpose (Potency)] This product is a glycopeptide antibiotic. It inhibits cell wall synthesis. It is highly active against Gram-positive bacteria. ● If no storage conditions are specified, store at room temperature. ● Bulk quote requests for some products are welcomed. Please contuct us. ● Listed products are intended for laboratory research use only, and not to be used for drug, food or human use. 033-21571 50mg CAS No. 21462-39-5 C18H33ClN2O5S · HCl=461.44 [Assay] 94.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] It is a lincomycin antibiotic that inhibits bacterial protein synthesis by binding of ribosome 50S subunit. Exhibits antimicrobial spectra to Gram-positive bacteria, anaerobic bacteria, and mycoplasma. 37 14. Antimicrobial and Antiprotozoal Agents n Azole Antimicrobial Agents Product Name Fluconazole for Cellbiology Wako Cat. No. Pkg. Size 068-04561 50mg 064-04563 500mg Product Name Miconazole Nitrate for Biochemistry CAS No. 86386-73-4 C13H12F2N6O=306.27 [Assay] 97.0+% (Titration) [Soluble in] Methanol [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] This product is a triazole antifungal agent. It inhibits biosynthesis of ergosterol that is a component of fungal cell membranes. Itraconazole for Pharmacology Research 092-05581 5g 098-05583 100g for Biochemistry 116-00551 100mg Pkg. Size 1g 5g 25g CAS No. 22832-87-7 C18H14Cl4N2O · HNO3=479.14 [Assay] 98.0+% (Titration) [Soluble in] Methanol [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] This product is an imidazole antimicrobial agent. It is a broad-spectrum antibiotic and is highly active against various fungi. Clotrimazole for Biochemistry CAS No. 84625-61-6 C35H38Cl2N8O4=705.63 [Assay] 98.0+% (HPLC) [Soluble in] Dichloromethane [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is a triazole antifungal agent. It inhibits biosynthesis of ergosterol that is a component of fungal cell membranes. Ketoconazole Wako Cat. No. 134-12661 130-12663 132-12662 035-16021 5g 033-16022 25g CAS No. 23593-75-1 C22H17ClN2=344.84 [Assay] 98.0+% (HPLC) [Soluble in] Dichloromethane [Intended Purpose (Potency)] This product inhibits cell respiration of fungi and destroys the cell membrane structures by promptly and powerfully changing cell membrane permeability. Isoconazole Nitrate for Biochemistry CAS No. 65277-42-1 C26H28Cl2N4O4=531.43 [Assay] 98+% (TLC) [Soluble in] Ethanol [Intended Purpose (Potency)] This product is an imidazole antimicrobial agent. It inhibits cytochrome P450 3A4. 096-06581 1g 092-06583 10g CAS No. 24168-96-5 C18H14Cl4N2O · HNO3=479.14 [Assay] 90.0+% (Titration) [Soluble in] Methanol [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] This product is an imidazole antimicrobial agent. This product inhibits cell respiration of fungi and destroys the cell membrane structures by promptly and powerfully changing cell membrane permeability. n Allylamine Antifungal Agents Product Name 14 (E )-N -(6,6-Dimethyl-2hepten-4-ynyl)-N -methyl-1naphthylmethylamine Hydrochloride Wako Cat. No. Pkg. Size 325-33191 1g 321-33193 5g CAS No. 78628-80-5 C21H25N · HCl=327.89 [Assay] 97.0+% [Soluble in] Water [Intended Purpose (Potency)] This product acts as a selective squalene epoxidase inhibitor. n New Quinolone Antimicrobial Agents Product Name Norfloxacin for Biochemistry Wako Cat. No. 142-06391 140-06392 Pkg. Size 5g 25g CAS No. 70458-96-7 C16H18FN3O3=319.34 [Assay] 98.0+% (Titration) (after drying) [Soluble in] Sodium hydroxide solution [Intended Purpose (Potency)] This product is active against Gramnegative bacilli and Gram-positive cocci. 38 Active Pharmaceutical Ingredients -Catalog- Product Name Nalidixic Acid for Biochemistry Wako Cat. No. 148-04791 146-04792 Pkg. Size 5g 25g CAS No. 389-08-2 C12H12N2O3=232.24 [Assay] 98.5+% (Titration) [Soluble in] Sodium hydroxide solution [Intended Purpose (Potency)] This product is highly active against Gram-negative bacteria. It acts as an antimicrobial agent by inhibiting DNA gyrase. Please visit the Wako Online Catalog: http://www.e-reagent.com Product Name Wako Cat. No. Ciprofloxacin Hydrochloride Monohydrate 032-18731 038-18733 for Biochemistry Pkg. Size 25g 50g Product Name Levofloxacin Hemihydrate for Genetic Research CAS No. 86393-32-0 C17H18FN3O3 · HCl · H2O=385.82 [Assay] 98.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is a new quinolone antibiotic. It inhibits bacterial type II DNA topoisomerase. It is active against an extremely broad spectrum of bacteria including Pseudomonas aeruginosa and MRSA. Ofloxacin for Genetic Research 157-02981 1g 153-02983 5g for Genetic Research 059-07971 1g 055-07973 5g Lomefloxacin Hydrochloride for Genetic Research Product Name Wako Cat. No. Butenafine Hydrochloride for Pharmacology Research 125-05941 1g 121-05943 5g 122-05951 1g 128-05953 5g CAS No. 98079-52-8 C17H19F2N3O3 · HCl=387.81 [Assay] 98.0+% (HPLC) [Soluble in] Sodium hydroxide solution [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] It acts as an antimicrobial agent by inhibiting DNA gyrase. Tosufloxacin Tosylate Monohydrate for Pharmacology Research CAS No. 74011-58-8 C15H17FN4O3=320.30 [Assay] 98.0+% (HPLC) [Soluble in] Sodium hydroxide solution [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] It acts as an antimicrobial agent by inhibiting DNA gyrase. n Benzylamine Antimicrobial Agents Pkg. Size CAS No. 138199-71-0 C18H20FN3O4 · 0.5H2O=370.38 [Assay] 98.0+% (HPLC) [Soluble in] Methanol [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] It acts as an antimicrobial agent by inhibiting DNA gyrase. CAS No. 82419-36-1 C18H20FN3O4=361.37 [Assay] 98.0+ % (HPLC) (mixture of isomers) [Soluble in] Sodium hydroxide solution [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is a new quinolone antibiotic. It inhibits bacterial type II DNA topoisomerase. It is active against an extremely broad spectrum of bacteria including Pseudomonas aeruginosa and MRSA. Enoxacin 1.5-Hydrate Wako Cat. No. 207-17101 5g 205-17102 25g CAS No. 107097-79-0 C19H15F3N4O3 · C7H8O3S · H2O=594.56 [Assay] 95.0+% (HPLC) [Soluble in] N,N -Dimethylformamide [Intended Purpose (Potency)] It acts as an antimicrobial agent by inhibiting DNA gyrase. n Polyene Antifungal Agents Pkg. Size 029-15881 1g 025-15883 5g Product Name Amphotericin B for Biochemistry CAS No. 101827-46-7 C23H27N · HCl=353.93 [Assay] 98.0+% (Titration) [Soluble in] Methanol [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] This product is active against Trichophyton and fungi. Wako Cat. No. 019-13364 015-13361 011-13363 Pkg. Size 100mg 250mg 1g CAS No. 1397-89-3 C47H73NO17=924.08 [Potency] 750 μg/mg or higher [Soluble in] DMSO [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is a polyene antifungal agent. It binds to cell membranes and causes membrane damage, thereby exerting antifungal effects. n Antiparasitic Agents Product Name Tinidazole for Biochemistry Wako Cat. No. Pkg. Size 201-19321 100g 203-19325 500g Product Name Chloroquine Diphosphate for Biochemistry CAS No. 19387-91-8 C8H13N3O4S=247.27 [Assay] 90.0+% (HPLC) [Soluble in] Methanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product causes DNA double-strand breaks. Metronidazole for Biochemistry 132-18061 130-18062 138-18063 5g 25g 100g Wako Cat. No. 038-17971 036-17972 034-17973 Pkg. Size 5g 25g 100g CAS No. 50-63-5 C18H26ClN3 · 2H3PO4=515.86 [Assay] 96.0+% (Titration) [Soluble in] Water [Intended Purpose (Potency)] This product acts as an antimalarial. Quinine CAS No. 443-48-1 C6H9N3O3=171.15 [Assay] 98.0+% (Titration) [Soluble in] Ethanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product causes DNA double-strand breaks. ● If no storage conditions are specified, store at room temperature. ● Bulk quote requests for some products are welcomed. Please contuct us. ● Listed products are intended for laboratory research use only, and not to be used for drug, food or human use. 170-00131 5g 178-00132 25g CAS No. 130-95-0 C20H24N2O2=324.42 [Assay] 90.0+% (Titration) [Soluble in] Ethanol [Intended Purpose (Potency)] This product acts as an antimalarial. 39 14 15. Antitumor Agents n Alkylating Agents Product Name Ifosfamide Wako Cat. No. for Pharmacology Research 090-05401 096-05403 Pkg. Size 50mg 500mg Product Name Dacarbazine for Pharmacology Research 029-09352 Wako 1st Grade 25g Procarbazine Hydrochloride for Pharmacology Research for Pharmacology Research 142-08471 250mg 148-08473 1g 043-29953 Pkg. Size 200mg 1g 161-22581 100mg 167-22583 1g CAS No. 366-70-1 C12H19N3O · HCl=257.76 [Assay] 98.0+% (Titration) [Soluble in] Water [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] This product is an alkylating agent. It forms cross-links to DNA and protein by alkylation. It inhibits DNA replication by this cross-linkage. CAS No. 55-98-1 C6H14O6S2=246.31 [Assay] 97.0+% (cGC) [Soluble in] Acetone [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] This product is an alkylating agent. It suppresses cell division by inhibiting DNA synthesis and replication. Nimustine Hydrochloride 047-29951 CAS No. 4342-03-4 C6H10N6O=182.18 [Assay] 98.0+% (Titration) [Soluble in] Dilute hydrochloric acid [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is an alkylating agent. It causes DNA damage by alkylation with diazomethane formed in metabolism. CAS No. 3778-73-2 C7H15Cl2N2O2P=261.09 [Assay] 98.0+% (HPLC) [Soluble in] Water [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] This product is an alkylating agent. Active metabolites of 4-hydroxy-ifosfamide and aldo-ifosfamide inhibit DNA synthesis in tumor cells. 1,4-Butanediol Dimethanesulfonate Wako Cat. No. CAS No. 55661-38-6 C9H13ClN6O2 · HCl=309.15 [Assay] 97.0+% (Titration) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is a nitrosourea compound. It is a water-soluble derivative of nitroso uric acid. It appears to decompose DNA into low molecules by alkylating cellular DNA and to inhibit DNA synthesis. n Antitumor Antibiotics Product Name Actinomycin D Wako 1st Grade 15 — Daunorubicin Hydrochloride for Pharmacology Research Wako Cat. No. 018-21264 014-21261 010-21263 Pkg. Size 1mg 5mg 25mg for Pharmacology Research for Biochemistry 049-31241 10mg 045-31243 50mg 058-08161 1mg 054-08163 5mg Wako Cat. No. 134-07911 Pkg. Size 10mg CAS No. 50-07-7 C15H18N4O5=334.33 [Potency]850+μg/mg [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product binds to guanine in DNA to cause cross-link breaks and inhibits DNA biosynthesis. CAS No. 50-76-0 C62H86N12O16=1255.42 [Assay] 95.0+% (HPLC) [Soluble in] Acetonitrile [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] This product binds to DNA and selectively inhibits RNA synthesis (especially rRNA synthesis), thereby exerting antitumor effects. CAS No. 23541-50-6 C27H29NO10 · HCl=563.98 [Assay] 95.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] This product is an anthracycline antibiotic. It acts on cells in the process of nucleic acid synthesis and directly binds to DNA to inhibit DNA synthesis. Epirubicin Hydrochloride Product Name Mitomycin C Doxorubicin Hydrochloride for Biochemistry 040-21521 10mg 046-21523 50mg CAS No. 25316-40-9 C27H29NO11 · HCl=579.98 [Potency]900+μg/mg [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is an anthracycline antibiotic. It causes DNA damage by inhibiting topoisomerase II. CAS No. 56390-09-1 C27H29NO11 · HCl=579.98 [Assay] 95.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is an anthracycline antibiotic. It binds to DNA of cancer cells and inhibits DNA and RNA polymerase chain reactions, thereby inhibiting nucleic acid biosynthesis and suppressing cell division. 40 Active Pharmaceutical Ingredients -Catalog- Please visit the Wako Online Catalog: http://www.e-reagent.com n Plant Antineoplastic Agents Product Name Docetaxel for Pharmacology Research Wako Cat. No. 047-31281 Pkg. Size 5mg Product Name Paclitaxel for Biochemistry CAS No. 114977-28-5 C43H53NO14=807.88 [Assay] 98.0+% (HPLC) [Soluble in] Ethanol [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] This product is a taxoid compound. It promotes tubulin polymerization in cells and inhibits tubulin depolymerization, thereby causing mitotic arrest in cells. Vinblastine Sulfate for Biochemistry 221-00751 10mg 227-00753 50mg for Pharmacology Research 229-01771 10mg 225-01773 50mg Etoposide for Pharmacology Research for Pharmacology Research 225-01631 2mg 221-01633 10mg Pkg. Size 1mg 5mg 25mg 100mg 055-08431 25mg 051-08433 100mg CAS No. 33419-42-0 C29H32O13=588.56 [Assay] 98.0+% (HPLC) [Soluble in] Methanol [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] This product is a podophyllin compound. It acts as a topoisomerase II inhibitor. Vinorelbine Ditartrate for Pharmacology Research CAS No. 2068-78-2 C46H56N4O10 · H2SO4=923.04 [Soluble in] Water [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] This product is an indole alkaloid. It exhibits higher toxicity. It inhibits tubuline polymerization by binding to β-tubuline and inhibits microtubule formation. Vindesine Sulfate CAS No. 33069-62-4 C47H51NO14=853.91 [Assay] 97.0+% (HPLC) [Soluble in] Methanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is a taxoid compound. It binds to β-tubuline to stabilize microtubules and inhibits mitosis by suppressing microtubule dynamics. CAS No. 143-67-9 C46H58N4O9 · H2SO4=909.05 [Assay] 97.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product suppresses cell division by inhibiting spindle formation and microtubule depolymerization. Vincristine Sulfate Wako Cat. No. 169-18616 169-18611 165-18613 163-18614 222-01641 10mg 228-01643 50mg CAS No. 125317-39-7 C45H54N4O8 · 2C4H6O6=1079.11 [Assay] 98.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] At mitosis, this product selectively acts on tubuline that is a component protein of microtubules, thereby inhibiting polymerization. CAS No. 59917-39-4 C43H55N5O7 · H2SO4=852.00 [Assay] 96.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at -80℃. [Intended Purpose (Potency)] At mitosis, this product acts on microtubules or tubuline that is a component protein of microtubules to inhibit polymerization. n Antimetabolites Product Name 5-Fluorouracil Wako Special Grade Wako Cat. No. 068-01401 064-01403 066-01402 Pkg. Size 1g 5g 25g Product Name Carmofur for Pharmacology Research for Biochemistry 204-19291 5g 202-19292 25g 15 Pkg. Size 035-20051 1g 031-20053 5g CAS No. 61422-45-5 C11H16FN3O3=257.26 [Assay] 98.0+% (HPLC) [Soluble in] Acetic Acid [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is converted into fluorouracil by metabolism in the living body and inhibits DNA synthesis. CAS No. 51-21-8 C4H3FN2O2=130.08 [Assay] 98.5+% (HPLC) [Soluble in] N,N -Dimethylformamide [Intended Purpose (Potency)] This product inhibits DNA synthesis by interfering with thymidylate synthase. Tegafur Wako Cat. No. Cytosine-1-β-D (+)-arabinofuranoside for Biochemistry CAS No. 17902-23-7 C8H9FN2O3=200.17 [Assay] 90.0+% (Titration) [Soluble in] Methanol [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] This product is converted into fluorouracil by metabolism in the living body and inhibits DNA synthesis. ● If no storage conditions are specified, store at room temperature. ● Bulk quote requests for some products are welcomed. Please contuct us. ● Listed products are intended for laboratory research use only, and not to be used for drug, food or human use. 030-11951 034-11954 036-11953 100mg 500mg 1g CAS No. 147-94-4 C9H13N3O5=243.22 [Assay] 98.0+% (Titration) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is a cytosine antimetabolite. It inhibits DNA polymerase I. 41 Product Name Doxifluridine for Pharmacology Research Wako Cat. No. 042-29901 048-29903 Pkg. Size 100mg 1g Product Name Gemcitabine Hydrochloride for Pharmacology Research CAS No. 3094-09-5 C9H11FN2O5=246.19 [Assay] 98.0+% (HPLC) [Soluble in] Water [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] This product is converted into fluorouracil by pyrimidine nucleoside phosphorylase which is an enzyme highly active in tumor tissues, and inhibits DNA synthesis. 6-Mercaptopurine Monohydrate for Biochemistry 130-07991 1g 136-07993 5g Wako Cat. No. 077-05671 073-05673 Pkg. Size 10mg 50mg CAS No. 122111-03-9 C9H11F2N3O4 · HC=299.66 [Assay] 97.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product appears to be effective in inducing cell death by inhibiting DNA synthesis. CAS No. 6112-76-1 C5H4N4S · H2O=170.19 [Assay] 98.0% - 102.0% (Titration) [Soluble in] Ammonia solution [Intended Purpose (Potency)] It inhibits DNA synthesis by antagonizing inosinic acid. n Hormone Preparations Product Name Estramustine Phosphate Disodium Salt for Biochemistry Wako Cat. No. Pkg. Size 053-08611 25mg 059-08613 250mg Product Name Methyltestosterone for Biochemistry CAS No. 52205-73-9 C23H30Cl2NO6P · 2Na=564.35 [Assay] 90.0+% (HPLC) [Soluble in] Water [Intended Purpose (Potency)] This product is an antiandrogen and inhibits microtubule formation. Bicalutamide for Biochemistry 021-18021 50mg 027-18023 500mg CAS No. 90357-06-5 C18H14F4N2O4S=430.37 [Assay] 90.0+% (HPLC) [Soluble in] Methanol [Intended Purpose (Potency)] This product competitively inhibits the binding between dihydrotestosterone and androgen receptors, thereby exerting antiandrogen effects. 15 Chlormadinone Acetate for Biochemistry 035-15161 1g 031-15163 5g CAS No. 302-22-7 C23H29ClO4=404.93 [Assay] 98.0+% (HPLC) [Soluble in] Acetonitrile [Intended Purpose (Potency)] This product is a kind of progesterone. It suppresses androgen involved in tumorigenesis. Medroxyprogesterone Acetate for Biochemistry 138-09991 1g 134-09993 5g Wako Cat. No. Pkg. Size 132-09933 1g 136-09931 5g CAS No. 58-18-4 C20H30O2=302.45 [Assay] 97.0+% (HPLC) [Soluble in] Ethanol [Intended Purpose (Potency)] This product is a synthetic testosterone. It suppresses progesteron-dependent tumor growth. Tamoxifen Citrate for Biochemistry 209-14361 205-14363 203-14364 207-14362 250mg 1g 5g 25g CAS No. 54965-24-1 C26H29NO · C6H8O7=563.64 [Assay] 98.0+% (Titration) [Soluble in] Methanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product is an estrogen analogue. It is also known as SERM (selective estrogen receptor modifier) and appears to selectively bind to estrogen receptors. Flutamide for Pharmacology Research 069-04851 2g 065-04853 10g CAS No. 13311-84-7 C11H11F3N2O3=276.21 [Assay] 98.0+% (HPLC) [Soluble in] Acetonitrile [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] This product is a nonsteroidal antiandrogen. It inhibits androgen from binding to androgen receptors. CAS No. 71-58-9 C24H34O4=386.53 [Assay] 98.0+% (HPLC) [Soluble in] 1,4-Dioxane [Intended Purpose (Potency)] This product is a progestogen. It suppresses estrogen. 42 Active Pharmaceutical Ingredients -Catalog- Please visit the Wako Online Catalog: http://www.e-reagent.com n Other Antitumor Agents Lentinan Product Name for Biochemistry — Irinotecan Hydrochloride Trihydrate for Biochemistry Wako Cat. No. 129-06181 125-06183 Pkg. Size 5mg 50mg Product Name Carboplatin for Biochemistry CAS No. 37339-90-5 [Soluble in] Water [Intended Purpose (Potency)] This product activates macrophages, killer T cells, and natural killer cells and enhances their antitumor immunity. 091-06651 25mg 097-06653 250mg for Biochemistry 186-01114 182-01116 182-01111 188-01113 50mg 100mg 250mg 1g Cisplatin for Pharmacology Research for Pharmacology Research 156-02691 5mg 152-02693 50mg 035-16043 Pkg. Size 25mg 250mg 033-20091 200mg 039-20093 2g CAS No. 15663-27-1 PtCl2 (NH3) 2=300.05 [Assay] 98.0+% (HPLC) [Soluble in] N,N- Dimethylformamide [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] This product forms platinum-DNA crosslinks within and between DNA chains and inhibits DNA replication and transcription. Imatinib Mesylate for Pharmacology Research 090-06861 100mg 096-06863 1g CAS No. 220127-57-1 C29H31N7O · CH4O3S=589.71 [Assay] 98.0+% (HPLC) [Soluble in] DMSO [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] This product acts as an ATP-competitive inhibitor of Bcl-Abl tyrosine kinase. CAS No. 302-79-4 C20H28O2=300.44 [Assay] 97.0+% (HPLC), 97.0+% (Titration) [Soluble in] Methanol [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] This product is a vitamin A derivative. It exhibits antitumor activity such as growth control of epithelial cells in the living body. Oxaliplatin 039-16041 CAS No. 41575-94-4 C6H12N2O4Pt=371.25 [Assay] 97.0+% (HPLC) [Soluble in] Water [Intended Purpose (Potency)] This product forms platinum-DNA crosslinks within and between DNA chains and inhibits DNA replication and transcription. CAS No. 136572-09-3 C33H38N4O6 · HCl · 3H2O=677.18 [Assay] 90.0+% (HPLC) [Soluble in] Water [Intended Purpose (Potency)] This product is a DNA synthesis inhibitor. It inhibits DNA synthesis by interfering with DNA topoisomerase I to break and reunite short strands of DNA. all-trans -Retinoic Acid Wako Cat. No. Pemetrexed Disodium Heptahydrate for Pharmacology Research CAS No. 61825-94-3 C8H14N2O4Pt=397.29 [Assay] 97.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] This product forms platinum-DNA crosslinks within and between DNA chains and inhibits DNA replication and transcription. 165-26261 10mg 161-26263 50mg CAS No. 357166-29-1 C20H19N5Na2O6 · 7H2O=597.48 [Assay] 98.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] This product inhibits DNA and RNA synthesis by interfering with enzymes in folic acid metabolism. 16. Antiviral Agents 15 n Anti-HIV Agents Product Name 3'-Azido-3'-deoxythymidine for Biochemistry Wako Cat. No. 015-14704 011-14706 011-14701 017-14703 019-14702 Pkg. Size 100mg 250mg 1g 5g 25g Product Name Didanosine for Pharmacology Research CAS No. 30516-87-1 C10H13N5O4=267.24 [Assay] 98.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] Nucleoside Analogue Reversetranscriptase Inhibitor (NRTI). Since it resembles nucleotide in its structure, it inhibits viral proliferation by competitively inhibiting substrate incorporation with viral DNA polymerase/ reverse transcriptase and arresting DNA strand elongation. ● If no storage conditions are specified, store at room temperature. ● Bulk quote requests for some products are welcomed. Please contuct us. ● Listed products are intended for laboratory research use only, and not to be used for drug, food or human use. Wako Cat. No. 16 Pkg. Size 040-31391 100mg 046-31393 1g CAS No. 69655-05-6 C10H12N4O3=236.23 [Assay] 98.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] Nucleoside Analogue Reversetranscriptase Inhibitor (NRTI). It inhibits viral proliferation by competitively inhibiting substrate incorporation with viral DNA polymerase and arresting DNA strand elongation. 43 Product Name 2',3'-Dideoxycytidine Wako Cat. No. 325-75711 Pkg. Size 500mg Product Name Lamivudine for Pharmacology Research CAS No. 7481-89-2 C9H13N3O3=211.22 [Assay] 97.0+% (HPLC) [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] Nucleoside Analogue Reversetranscriptase Inhibitor (NRTI). It inhibits viral proliferation by competitively inhibiting substrate incorporation with viral DNA polymerase and arresting DNA strand elongation. Wako Cat. No. Pkg. Size 128-05811 100mg 124-05813 1g CAS No. 134678-17-4 C8H11N3O3S=229.26 [Assay] 97.0+% (HPLC) [Soluble in] Methanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] Nucleoside Analogue Reversetranscriptase Inhibitor (NRTI). It inhibits viral proliferation by competitively inhibiting substrate incorporation with viral DNA polymerase and arresting DNA strand elongation. n Anti-Herpesvirus Agents Product Name 9-β-D-Arabinofuranosyladenine Wako Cat. No. 359-13471 Pkg. Size 1g Product Name Penciclovir for Pharmacology Research CAS No. 5536-17-4 C10H13N5O4=267.24 [Assay] 97.0+% (HPLC) [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] It is thought to be an active form of Ara− A (Ara−ATP) in vivo and inhibit DNAdependent DNA polymerase. Acyclovir for Biochemistry 019-17421 250mg 015-17423 1g Wako Cat. No. 169-24221 165-24223 Pkg. Size 100mg 1g CAS No. 39809-25-1 C10H15N5O3=253.26 [Assay] 98.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] It inhibits viral proliferation by competitively inhibiting substrate incorporation with viral DNA polymerase/reverse transcriptase and arresting DNA strand elongation. CAS No. 59277-89-3 C8H11N5O3=225.20 [Assay] 99.0+% (HPLC) [Soluble in] Sodium hydroxide solution [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] Antiviral agent (antiherpes activity). It inhibits viral proliferation by competitively inhibiting substrate incorporation with viral DNA polymerase/reverse transcriptase and arresting DNA strand elongation. n Other Viral Agents Product Name Ganciclovir for Biochemistry Wako Cat. No. 078-04481 074-04483 Pkg. Size 250mg 1g Product Name Tenofovir for Pharmacology Research CAS No. 82410-32-0 C9H13N5O4=255.23 [Assay] 98.0+% (HPLC) [Soluble in] Sodium hydroxide solution [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] Nucleoside Analogue Reversetranscriptase Inhibitor (NRTI). It inhibits viral proliferation by competitively inhibiting substrate incorporation with viral DNA polymerase/reverse transcriptase and arresting DNA strand elongation. 16 Ribavirin for Pharmacology Research 182-02331 250mg 188-02333 1g CAS No. 36791-04-5 C8H12N4O5=244.20 [Assay] 98.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] It inhibits viral proliferation by inhibiting viral RNA polymerase. 44 Active Pharmaceutical Ingredients -Catalog- Wako Cat. No. 207-17961 203-17963 Pkg. Size 100mg 1g CAS No. 147127-20-6 C9H14N5O4P=287.21 [Assay] 97.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] It arrests DNA strand elongation by competitively inhibiting substrate incorporation with viral DNA polymerase. Zanamivir for Biochemistry 264-02021 100mg 260-02023 500mg CAS No. 139110-80-8 C12H20N4O7=332.31 [Assay] 90.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] Neuraminidase inhibitor. Neuraminidase enzymes catalyze the hydrolysis of terminal sialic acid residues in glycosidic linkages and are found on the surface of microorganism, plant and animal cells. Zanamivir prevents viruses that have proliferated in the host cell from escaping from the host cell and infecting other cells. Please visit the Wako Online Catalog: http://www.e-reagent.com 17. Immune-Suppressive Agents n Specific Immunosuppressive Agents Product Name Ciclosporin A for Biochemistry Wako Cat. No. Pkg. Size Product Name 035-16303 100mg 039-16301 200mg Rapamycin (mixture of isomers) for Cellbiology CAS No. 59865-13-3 C62H111N11O12=1202.61 [Assay] 97.0+% (HPLC) [Soluble in] Methanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] The product is a typical immunosuppressant used for prevention of graft rejection after organ transplantation. It is a cyclic polypeptide consisting of 11 amino acids and inhibits secretion of interleukin 2 from helper T cells, which promote immune reaction, and thus inhibits immunity. FK506 for Biochemistry 063-06071 5mg Wako Cat. No. 184-02531 180-02533 188-02534 Pkg. Size 1mg 10mg 50mg CAS No. 53123-88-9 C51H79NO13=914.17 [Soluble in] Methanol [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] The product is a structural analog of FK506 and it forms a complex with FK506 binding protein (FKBP) in analogy with FK506, but it does not inhibit the activity of calcineurin in contrast to FK506. Rapamycin-FKBP complex binds to mTOR, inhibits its kinase activity and inhibits IL-2 signaling. Everolimus for Pharmacology Research 051-08771 5mg 057-08773 25mg CAS No. 159351-69-6 C53H83NO14=958.22 [Assay] 98.0+% (HPLC) [Soluble in] Methanol [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] It exerts an anti-tumor effect through the direct mechanism of action in which tumor-cell signal transduction is inhibited and tumor cell proliferation is suppressed by forming a complex with FKBP12 in the cell and selectively inhibiting the mTOR functions, and the indirect mechanism of action in which VEGF production in tumor cells and vascular endothelial cell proliferation via VEGF are suppressed, thereby suppressing angiogenesis. CAS No. 104987-11-3 C44H69NO12=804.02 [Assay] 95.0+% (HPLC) [Soluble in] Acetonitrile [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] Potent immunosuppressant, neuroprotective agent and nerve regenerator. In vitro, FK506 has been shown to block T cell proliferation. Although it normally forms a complex with FK506 binding protein 12 (FKBP12), the molecule can also bind with calcineurin to downregulate the expression of various cytokines such as IL-2 and interferon, which subsequently leads to decreased extracellular T cell differentiation/ proliferation. n Cytotoxic Agents Product Name Cyclophosphamide Monohydrate for Biochemistry Wako Cat. No. 030-12953 034-12951 Pkg. Size 1g 5g Product Name Mizoribine for Pharmacology Research CAS No. 6055-19-2 C7H15Cl2N2O2P · H2O=279.10 [Assay] 97.0+% (Titration) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] The product is an alkylating agent. It inhibit synthesis and replication of DNA as well as mitosis by alkylation of nucleic acids. Methotrexate for Biochemistry 139-13571 100mg 135-13573 1g Wako Cat. No. 138-17061 134-17063 Pkg. Size 100mg 1g CAS No. 50924-49-7 C9H13N3O6=259.22 [Assay] 98.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] The product is an antimetabolite that inhibits synthesis of the purine nucleotides. It inhibits nucleic acid synthesis and shows an inhibitory action on proliferation of T-cells and B-cells. CAS No. 59-05-2 C20H22N8O5=454.44 [Assay] 98.0+% (HPLC) [Soluble in] Sodium carbonate solution [Intended Purpose (Potency)] It shows the effect of interference with folic acid metabolism. ● If no storage conditions are specified, store at room temperature. ● Bulk quote requests for some products are welcomed. Please contuct us. ● Listed products are intended for laboratory research use only, and not to be used for drug, food or human use. 17 45 18. Vitamins (1) Water-soluble vitamins n Vitamin B1 Product Name Thiamin Hydrochloride Wako Special Grade n Vitamin B2 Wako Cat. No. 203-00851 201-00852 209-00853 205-00855 Pkg. Size 1g 25g 100g 500g Product Name Riboflavin Tetrabutyrate for Biochemistry Wako Cat. No. Pkg. Size 185-00861 5g 183-00862 25g CAS No. 752-56-7 C33H44N4O10=656.73 [Assay] 98.0 - 102.0% (Absorptiometry) (after drying) [Soluble in] Chloroform [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] The product is a vitamin B2 compound. It affects oxidation-reduction reactions as a flavin coenzyme. CAS No. 67-03-8 C12H17ClN4OS · HCl=337.27 [Assay] 98.0+% (HPLC) (calculated on the dehydrous basis) [Soluble in] Water [Intended Purpose (Potency)] The product is a vitamin B1 compound. It affects carbohydrate metabolism. n Vitamin-Related Compounds Product Name Nicotinic Acid Wako Special Grade Wako Cat. No. 142-01232 144-01231 146-01235 Pkg. Size 25g 100g 500g Product Name Wako Cat. No. (±)-1,2-Dithiolane-3-valeric Acid 208-00921 1g 204-00923 10g Wako Special Grade CAS No. 1077-28-7 C8H14O2S2=206.33 [Assay] 98.0+% (Titration) [Soluble in] Ammonium chloride - diluted ammonia aqueous solution [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] The product is α-lipoic acid compound. It involves with oxidative decarboxylation of pyruvic acid as well as α-ketoglutaric acid as a coenzyme and produce an acetoacetyl-CoA and promotes energy metabolism. CAS No. 59-67-6 C6H5NO2=123.11 [Assay] 98.0+% (Titration) [Soluble in] Water [Intended Purpose (Potency)] The product is a dehydratase coenzyme. It affects oxidation-reduction reactions. Folic Acid Wako Special Grade 062-01801 1g 060-01802 25g Pkg. Size CAS No. 59-30-3 C19H19N7O6=441.40 [Assay] 98.0 - 102.0% (Absorptiometry) (calculated on the dehydrous basis) [Soluble in] Sodium hydroxide solution [Intended Purpose (Potency)] It affects nucleic acid metabolism. n Vitamin B5-Related Compounds Product Name D (+)-Panthenol Wako Special Grade Wako Cat. No. Pkg. Size 169-12952 25g 163-12955 500g CAS No. 81-13-0 C9H19NO4=205.25 [Assay] 98.0+% (Titration) [Soluble in] Water [Intended Purpose (Potency)] The product is a vitamin B compound. Panthenol being incorporated in vivo is easily oxidized to pantothenic acid and comes into effective. 18 Sodium (+)-Pantothenate 198-05651 1g 196-05652 25g Product Name Calcium (+)-Pantothenate Wako Special Grade Wako Cat. No. 031-14161 039-14162 033-14165 Pkg. Size 1g 25g 500g CAS No. 137-08-6 C18H32CaN2O10=476.53 [Assay] 98.0+% (Titration) (after drying) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] The product is a vitamin B compound. It affects metabolic reaction. CAS No. 867-81-2 C9H16NNaO5=241.22 [Assay] 95.0+% (Titration) [Soluble in] Water [Intended Purpose (Potency)] The product is a vitamin B compound. It affects metabolic reaction. It is extremely hygroscopic. 46 Active Pharmaceutical Ingredients -Catalog- Please visit the Wako Online Catalog: http://www.e-reagent.com n Vitamin B6 Product Name Pyridoxine Hydrochloride Wako Special Grade Wako Cat. No. 165-05401 163-05402 161-05403 Pkg. Size 1g 25g 100g Product Name Pyridoxal Hydrochloride for Cellbiology CAS No. 58-56-0 C8H11NO3 · HCl=205.64 [Assay] 98.0+% (Titration) [Soluble in] Water [Intended Purpose (Potency)] The product is a vitamin B6 compound. Pyridoxal Phosphate Monohydrate Wako Special Grade 169-20941 165-20943 163-20944 Wako Cat. No. 160-23651 168-23652 162-23655 Pkg. Size 1g 25g 500g CAS No. 65-22-5 C8H9NO3 · HCl=203.62 [Assay] 98.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] The product is a vitamin B6 oxide. It shows the effect of vitamin B6. 100mg 1g 10g CAS No. 41468-25-1 C8H10NO6P · H2O=265.16 [Assay] 98.0+% (Absorptiometry) (after drying) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] The product is a coenzyme form of vitamin B6. It affects amino acid metabolism. n Vitamin B7 Product Name (+)-Biotin Wako 1st Grade Wako Cat. No. 023-08711 023-08716 029-08713 021-08712 027-08714 Pkg. Size 100mg 500mg 1g 5g 10g CAS No. 58-85-5 C10H16N2O3S=244.31 [Assay] 97.0+% (Titration) [Soluble in] Sodium hydroxide solution [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] The product is a vitamin B7. It affects as a coenzyme on carbon dioxide fixation reaction and carboxyl-group transfer reaction. n Vitamin B12 Product Name Cyanocobalamin Wako Special Grade Wako Cat. No. 220-00341 226-00343 224-00344 220-00346 Pkg. Size 10mg 100mg 1g 10g Product Name Methylcobalamin for Biochemistry CAS No. 68-19-9 C63H88CoN14O14P=1355.37 [Assay] 95.0+% (Absorptiometry) (calculated on the dried basis) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] The product is a vitamin B12 compound. It involves with the transmethylation reaction and the intramolecular carboxyl-group transfer reaction. Hydroxocobalamin Acetate for Biochemistry 081-05631 087-05633 085-05634 Wako Cat. No. 138-14261 134-14263 132-14264 Pkg. Size 100mg 1g 5g CAS No. 13422-55-4 C63H91CoN13O14P=1344.38 [Assay] 95.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] The product is a vitamin B12 compound. It involves with the transmethylation reaction and the intramolecular carboxyl-group transfer reaction. 100mg 1g 5g CAS No. 22465-48-1 C62H89CoN13O15P · C2H4O2=1406.41 [Assay] 95.0+% (Absorptiometry) (calculated on the dried basis) [Soluble in] Water [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] Vitamin B12. Its deficiency causes pernicious anemia. The coenzyme type B12 is involved in the synthesis of nucleic acids (especially DNA) through transmethylation reaction. ● If no storage conditions are specified, store at room temperature. ● Bulk quote requests for some products are welcomed. Please contuct us. ● Listed products are intended for laboratory research use only, and not to be used for drug, food or human use. 47 18 n Derivatives of Vitamin B1 Product Name Fursultiamine Hydrochloride (mixture of isomers) for Pharmacology Research n Vitamin C Wako Cat. No. Pkg. Size 062-05061 5g 060-05062 25g Product Name L (+)-Ascorbic Acid JIS Special Grade Wako Cat. No. 012-04802 014-04801 016-04805 Pkg. Size 25g 100g 500g CAS No. 50-81-7 C6H8O6=176.12 [Assay] 99.6+% (mass/mass) (Titration) [Soluble in] Water [Intended Purpose (Potency)] The product is a vitamin C compound. It shows effect on collagen biosynthesis. CAS No. 2105-43-3 C17H26N4O3S2 · HCl=435.00 [Assay] 98.0+% (HPLC) (mixture of isomers) [Soluble in] Water [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] The product is a derivative of vitamin B1. It has been considered to improve neurologic dysfunction and myocardial metabolism, and enhance intestinal movement. (2) Fat-soluble vitamins n Vitamin D2 Product Name Calciferol Wako Special Grade n Vitamin D3 Wako Cat. No. 039-00291 Pkg. Size 1g Product Name Cholecalciferol Wako Special Grade CAS No. 50-14-6 C28H44O=396.66 [Soluble in] Ethanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] The product is a vitamin D2 compound. n Vitamin E Product Name (±)-α-Tocopherol Acetate Wako 1st Grade Wako Cat. No. 224-00361 220-00363 Pkg. Size 100mg 1g CAS No. 67-97-0 C27H44O=384.64 [Assay] 97.0+% (HPLC) [Soluble in] Ethanol [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] The product is a vitamin D3 compound. n Vitamin K1 Wako Cat. No. 201-18483 203-18482 205-18481 Pkg. Size 5g 25g 100g Product Name Vitamin K1 CAS No. 7695-91-2 C31H52O3=472.74 [Assay] 96.0+% (HPLC) [Soluble in] Acetone [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] The product is a vitamin E compound. Wako Cat. No. 221-00371 227-00373 229-00372 Pkg. Size 1g 5g 25g CAS No. 84-80-0 C31H46O2=450.70 [Assay] 97.0 - 102.0% (Absorptiometry) [Soluble in] 2,2,4-Trimethylpentane [Storage condition] Keep at 2-10℃. [Intended Purpose (Potency)] The product is a vitamin K1 compound. n Vitamin-Related Compounds Product Name 18 Cocarboxylase Wako Cat. No. 035-03831 031-03833 033-03832 Pkg. Size 100mg 1g 25g CAS No. 154-87-0 C12H19ClN4O7P2S=460.77 [Assay] 90.0+% (HPLC) [Soluble in] Water [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] The product is a diphosphate (pyrophosphate) ester compound of thiamine (vitamin B1). It is a coenzyme that concerns with decarboxylation by carboxylase. 48 Active Pharmaceutical Ingredients -Catalog- Product Name Flavin Adenine Dinucleotide Disodium Salt n -Hydrate Wako Cat. No. 068-00161 064-00163 062-00164 Pkg. Size 10mg 100mg 1g C27H31N9Na2O15P2 · nH2O (C27H31N9Na2O15P2=829.51) [Assay] 98.0 - 102.0+% (Absorptiometry) (calculated on the anhydrous basis) [Soluble in] Water [Storage condition] Keep at -20℃. [Intended Purpose (Potency)] It affects the intracellular oxidationreduction system and the mitochondrial electron transfer system as a flavin coenzyme and widely involves with in vivo metabolism of carbohydrates, lipids, and proteins. Please visit the Wako Online Catalog: http://www.e-reagent.com 19. Contrast Agents n X-ray Contrast Agents Product Name Iopamidol Wako Cat. No. for Pharmacology Research 091-05551 099-05552 Pkg. Size 5g 25g Product Name Barium Sulfate Wako Cat. No. 022-00425 Wako 1st Grade CAS No. 60166-93-0 C17H22I3N3O8=777.09 [Assay] 98.0+% (HPLC) [Soluble in] Water [Storage condition] Keep below 25℃. [Intended Purpose (Potency)] Iodine, which is a constituent element, has a high X-ray absorption activity. BaSO4 Pkg. Size 500g CAS No. 7727-43-7 BaSO4=233.39 [Intended Purpose (Potency)] It is used as a X-ray contrast agent since its absorption capacity of X-ray is large, its solubility is low, and it is harmless. n Fluorescent Dyes Product Name Fluorescein Wako Cat. No. 065-00252 Wako Special Grade Pkg. Size 25g Uranine Product Name Wako Cat. No. 213-00092 JIS Special Grade CAS No. 2321-07-5 C20H12O5=332.31 [Soluble in] Ethanol, Sodium hydroxide solution [Intended Purpose (Potency)] It has a fluorescence imaging effect. Pkg. Size 25g CAS No. 518-47-8 C20H10Na2O5=376.28 [Soluble in] Water [Intended Purpose (Potency)] It has a fluorescence imaging effect. Newly-Released Catalog Inhibitors -catalog1. Kinase Inhibitors 2. Protein Phosphatase Inhibitors 3. Inhibitor Cocktail Sets 4. Calcium Singnaling related Inhibitors 5. Ion Channel-related Blockers 6. G-protein Signaling and Second Messenger-related Inhibitors 19 7. Neurotransmitter Inhibitors If you would like to receive the catalog, please contact our distributor or visit our website and complete a "contact us" form: www.wako-chem. co.jp/english/index.htm . ● If no storage conditions are specified, store at room temperature. ● Bulk quote requests for some products are welcomed. Please contuct us. ● Listed products are intended for laboratory research use only, and not to be used for drug, food or human use. 49 for Research Use Only Active Pharmaceutical Ingredients -Catalog- 14803GK