CAPILLAIRE recto/Fr - in

PROPERTIES
AQUAXYLTM
Moisturiser and
restructurer
3
SEPICAPTM
MP
LIPACIDETM
UG
*SEPPIC being:
LIPACIDETM SEPICALMTM SEPICALMTM SEPITONICTM
C8G
S
VG
M3
SEPPIC S.A.
Tour KUPKA C
7, boulevard Franck Kupka
92039 Paris La Défense cedex
FRANCE
Tél. : 33 (0)1 55 91 57 00
Fax: 33 (0) 1 55 91 50 50
3
Multi-protection
3
Purifyers of
oily hair
3
Anti
dandruff
3
3
3
Soothers and
dermoprotectors
3
Formulas for
fragile hair
GIVAUDAN LAVIROTTE
S.A.
3
56, rue Paul Cazeneuve
BP 8344 – 69008 Lyon
FRANCE
Tél.: +33 (0) 4 78 61 55 00
Fax: +33 (0) 4 72 05 60 89
3
3
and, depending on the country:
3
Hair
growthing
ECOCERT
validation
INCI
(CTFA)
name
3
Sodium
Cocoyl
aminoacids
Xylitylglucoside
&
&
potassium
Anhydroxylitol
dimethicone
& Xylitol
PEG-7
panthenyl
phosphate
3
3
3
3
Undecylenoyl
glycine
Capryloyl
glycine
3
SEPPIC Inc
30, Two Bridges Road, suite
210
Fairfield, New Jersey 070041530
USA
Tél. : (1) 973 882 5597
Fax : (1) 973 882 5178
Sodium
Cocoyl
Sodium
Magnesium
aminoacids &
Palmitoylproline aspartate &
sarcosine
&
zinc
&
nymphaea
gluconate &
magnesium
alba flower
copper
aspartate &
extract
gluconate
potassium
aspartate
SEPPIC UK Ltd
50 Salisbury Road
PO Box 338 - Hounslow
TW4 6SH - ENGLAND
Tél. : (44) 208 577 8800
Fax : (44) 208 570 2106
Glossary (z):
am : Active Matter
c p : Commercial Product
SLES : Anionic surfactant widely used in foaming formulas
(Sodium Lauryl Ether Sulfate)
EM : Electronic Microscopy
MIC : Minimum Inhibitory Concentration
HET-CAM test : Alternative methods to animal testing for irritation evaluation
SEPPIC ITALIA SRL
Via Quarenghi 27
20151 Milano
ITALY
Tél. : (39) 02 38009110
Fax : (39) 02 38009140
SEPPIC Chine
Room 510 Jin Tai Building
58 South Mao Ming Road
Shanghai 200020 - CHINA
Tél.: (86-21) 64 66 01 49
Fax : (86-21) 64 66 11 09
Nota
SEPPIC GmbH
The analytical specifications warranted are only those mentioned on the certificate of analysis supplied
with each delivery of the product.
"Please check with SEPPIC* that you have the most recent version of this document".
AQUAXYLTM - SEPICAP MPTM - LIPACIDETM C8G - LIPACIDETM UG - SEPICALMTM S - SEPICALMTM VG and
SEPITONICTM M3 are SEPPIC registered trademarks.
SEPPIC* is a subsidiary of the AIR LIQUIDE group.
© 2007 - SEPPIC
C3576/GB/01/May 2007
Création Galbe/2372 - Photos : gettyimages
Except as set forth above, SEPPIC* makes no warranties, whether express, implied or statutory, as to the
product which is the subject of this document . Without limiting the generality of the foregoing, SEPPIC*
makes no warranty of merchantability of the product or of the fitness of the product for any particular
purpose. Buyer assumes all risk and liability resulting from the use or sale of the product, whether singly or in combination with other goods. The information set forth herein is furnished free of charge and
is based on technical data that SEPPIC* believes to be reliable. It is intended for use by persons having
technical skill and at their own discretion and risk. Since conditions of use are outside SEPPIC*'s control,
SEPPIC* makes no warranties, express or implied, and assumes no liability in connection with any use
of this information. Nothing herein is to be taken as a license to operate under or a recommendation to
infringe any patents.
Ettore-Bugatti Str 6-14
51149 Köln-Porz - GERMANY
Tél.: +49 (0) 220 3890 3100
Fax : +49 (0) 220 3890 3199
SEPPIC Belgium NV
Nieuwe Weg 1
Haven 1053
B – 2070 Zwijndrecht
BELGIUM
Tél.: +32 3 250 3911
Fax: +32 3 250 3912
www.seppic.com
ON -
R
AQUAXYL
TM
TI
- H AI
HY
D
T
EP
CONC
RA
I N N O VA
CLEVER MOISTURISATION!
Two water sources in the hair
Essential to maintain the hair’s mechanical
and protective properties.
1st moisturising
level :
SUPERFICIAL
2nd moisturising
level :
DEEP
Water
weakly
bound
to the surface
of the hair.
Water
strongly
bound to the
hydrophilic part
of the hair, in the
core of the cuticle
Easily eliminated
by hairdryer.
Difficult to
eliminate.
Dry hair (open scales)
is a consequence of a loss of the
2nd level of moisturisation.
⇒ weakened hair!
CONTROL :
Bleached
hair lock (5x)
EM z: x600
% moisture reserves
5.3 %
Improvement of
deep moisturisation
5.1 %
4.9 %
4.7 %
4.5 %
3% TM
Control AQUAXYL
Curative treatment
Rinse-off product
1.5% AQUAXYLTM
Caucasian hair
EM : x600
Leave on product
1.5% AQUAXYLTM
Caucasian hair
EM : x600
Rinse-off product
3% AQUAXYLTM
Asian hair
EM : x600
Ý
At 1.5%, AQUAXYLTM effectively protects the hair fibre and its
appearance (rinse-off or leave on products).
At 3%, it restores moisture of damaged hair to the core
of cuticle ( rinse-off products). For brilliant hair.
ON -
R
AQUAXYL
TM
TI
- H AI
HY
D
T
EP
CONC
RA
I N N O VA
FOR FOAM ENHANCEMENT & SMOOTHY SENSATION!
1. IMPROVEMENT OF
FORMULAS’ TOLERANCE
12
X
X
10
X
X
Irritant
z
Reduction of the SLES
irritant effect by the
addition of AQUAXYLTM
8
6
HET-CAM Index
X
Moderatly
irritant
X
4
X
Slightly
irritant
2
No irritant
0
10% + 0%
8% + 2%
6% + 4%
5% + 5%
4% + 6%
2% + 8%
1% + 9%
% SLES
% AQUAXYLTM
X Evaluation of SLES irritation
Evaluation of SLES irritation in presence of AQUAXYLTM
Irritation effects observed by HET-CAMz test :
Application of the diluted product to a chorioallantoic membrane of egg.
Ý
AQUAXYLTM reduces the irritation effects of surfactants
such as SLES (Proved with a finished formula SLES ≤ 8% and
AQUAXYLTM ≥ 2%).
2. IMPROVEMENT OF FORMULAS’
SENSORY PROFILE
Softness
Softness
8
10
6
8
6
4
2
Density
0
Bubble size
Foam
volume
1st wash
Foam volume
after dilution
SLES 8% am/ AQUAXYLTM 2% cp
SLES alone 8% am
4
Density
2
0
Bubble size
Foam
volume
1st wash
Foam volume
after dilution
ORAMIXTM NS10 8% am/ AQUAXYLTM 2% cp
Control ORAMIXTM NS10 8% am
Handwashing by panelists with differents formulas, using a standardized method.
Ý
AQUAXYLTM significantly increases the softness and volume
of the foam and improves the hygiene formula’ sensory profile
(confirmed also with 2% of AQUAXYLTM and several non ionic
surfactants such as ORAMIXTM range).
SOS SPECIAL
ITCHY SCALP!
1. DERMOPROTECTOR EFFECT
STRESS
COOH
NH2
NH2
COOH
Healthy scalp
(Acid pH)
Unbalanced scalp
(Basic pH)
LIPOAMINOACID :
Restoration of the acidic pH
(COOH free)
Ý
Thanks to their structure (COOH free), LIPACIDETM C8G,
SEPICALMTM S, SEPICALMTM VG protect the scalp. They restore
its “acid coat”.
6
5
Very red
scalp
Test on volunteers:
- Formula 6679A
- 2% LIPACIDETMC8G
40 volunteers with capillary
seborrheic dermatitis – 2 months
of treatment, one application every
3 days.
4
Redness score
3
Slightly red
scalp
2
1
Normal scalp
0
D0
D 15
D 30
D 45
D 60
Days
Ý
LIPACIDETM C8G formulated at 2% removes scalp irritation,
from the first month of treatment.
2. MODULATING EFFECT
ON THE INFLAMMATORY CASCADE
STRESSED SCALP
Inflammatory enzymes
SEPICALM
TM
VG
Free radicals
Cyclo-oxygenase
DNA
alteration
Prostaglandines
Cell death
Sensation
of pain,
inflammation
SEPICALMTM VG &
SEPICALMTM S
Elastase
SEPICALMTM S
Hyaluronidase
Lipooxygenase
Leukotriens
Destruction of
Cutaneous proteins
(elastin & collagen)
Inflammation
REDNESS, HEAT, PAIN
Ý
SEPICALMTM S and SEPICALMTM VG decrease the concentration of
inflammation mediators. They work for a complete anti-stress
protection against external agressions.
Real feeling of well-being and comfort.
YES TO SHINY HAIR,
NO TO OILY HAIR!
LIPACIDETM C8G
LIPACIDETM UG
Finasteride
30 ng/mL amz
(positive control)
-50 %
(0.1 % am)
-33 %
(0.01 % am)
-35 %
% anti 5α-reductase activity
Ý
LIPACIDETM C8G and LIPACIDETM UG modulate the
5α-reductase activity (enzyme responsable for the sebum
production).
Test on volunteers:
8
- Formula 6679A
- 2% LIPACIDETM C8G
Very oily
scalp and
hair
40 volunteers with capillary
seborrheic dermatitis – 2 months
of treatment one application every
3 days.
Sebum score
6
Slightly oily
scalp and
normal hair
4
2
Normal
scalp and hair
0
D0
D 15
D 30
D 45
D 60
Days
Ý
LIPACIDETM C8G and LIPACIDETM UG effectively limit the
sebum production (clinicaly proven from the first month of
treatment with 2% of LIPACIDETM C8G in the formula).
MULTI-FUNCTIONAL
THERMO-ACTIVE PROTECTION!
STRESS
ATTACK
Limits the formation of lipid
peroxides (radical scavenging effect)
Prevents keratin breakdown
Prevents flaking
SEPICAPTM MP, “thermo-active”,
superactivated by hairdryer
heat (+80% of efficiency).
Restores normal cell division
Stimulates protein metabolism
Root
Ý
SEPICAPTM MP restructures and protects stressed hair.
Proven efficacy on stressed and damaged hair, demonstrated both
with in vivo and in vitro test.
AMAZING P
FOR HAIR
DANDRUFF!
Germ tested :
Pytyrosporum ovale (pH = 5)
Minimum Inhibitory
Concentration
LIPACIDETM C8G
0.75 % am
LIPACIDETM UG
0.01 % am
Ý
LIPACIDETM C8G and LIPACIDETM UG control the proliferation
of germs responsible for dandruff.
Significant
reduction of 55%*
squamae
12
Weight of squamae (mg)
10
Test on
volunteers:
- Capillary lotion
- Formula 6723A
- 2% LIPACIDETM UG
10 Volunteers
8
6
4
2
0
Before
treatment
* p<0.05
10
After 28 days
of treatment
Many large
squamae
8
Test on
volunteers:
- Shampoo
- Formula 6679A
- 2% LIPACIDETM C8G
40 Volunteers
6
Squamae Score
PROGRAM
R CRISIS!
LET’S COMBAT
4
Few small
squamae
2
No squamae
0
D0
D 15
D 30
D 45
D 60
Days
Ý
LIPACIDETM C8G and LIPACIDETM UG clearly improve the state
of desquamation. From the first month of treatment, squamae
decrease in size and number.
FORMULAS FOR
FRAGILE HAIR!
Minimum Inhibitory
Concentration
LIPACIDETM C8G
Bacteria
Fungi
LIPACIDETM UG
UG + C8G
++
+
+++
+
++
+++
Ý
LIPACIDETM C8G and LIPACIDETM UG allow formulation of
products with reduced preservative quantity. (SEPPIC patent).
LIPACIDETM C8G reduces effectively the proliferation of bacteria.
LIPACIDETM UG inhibits fungi.
Their synergy is indicated for a best result.
DON’T LET
YOUR HAIR DOWN!
1. HELP MAINTAIN HAIR GROWTH
Air pollution
æO2 available
UV, chemical
aggressions
Ageing
Stress, fatigue,
diet, cigarette
BURNED OUT CELLULAR ENGINE ! HAIR CRISIS!
Fragile, dull, tired.
SEPICAPTM MP
Preventive protection
to the core of stressed hair
SEPITONICTM M3
Cellular chrono-energizer
+ 17 % of
division
+ 53 % of
division
6
5.7
Cellular division
by quantity of DNA (µg/puit)
5
SEPITONICTM M3 stimulates the synthesis
of cellular energy mediator and metabolics
(ATP-ADN-proteins) via an optimized
cellular respiration.
4.3
4
3
3.7
2
1
0
Cells +
heat
Cells +
0.5 ppm am
SEPICAPTM MP
+ heat
Cells +
1 ppm am
PANTHENOLTM
+ heat
SEPICAPTM MP stimulates the cellular division of
stressed keratinocytes.
Ý
SEPITONICTM M3 and SEPICAPTM MP reawaken cellular
metabolism. The hair base is toned and revitalised.
2. LIMITED HAIR LOSS
LIPACIDETM C8G
LIPACIDETM UG
TESTOSTERONE
5α-REDUCTASE
5α- DEHYDROTESTOSTERONE
3- HYDROXYSTEROIDE
DESHYDROGENASE
5α- ANDROSTANEDIOLS
activation of genes responsible for the miniaturization of follicules.
è premature telogenic phase (hair death).
Ý
LIPACIDETM C8G and LIPACIDETM UG are recommended for
hair-loss control, thanks to their anti-5α-reductase activity.