2012 - 2013 Annual Report

Transcription

2012 - 2013 Annual Report
School of Medicine
Faculty of Health Sciences
2012 RESEARCH REPORT
Regional Clinical
Practice Research
Centre
2012 Research
March 2013
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MESSAGE FROM THE DIRECTOR OF THE CENTRE ....................................................................... - 4 CENTRE MEMBERSHIP.............................................................................................................. - 5 PROFESSIONAL, ACADEMIC AND HONORARY STAFF................................................................................... - 5 RESEARCH GRANTS AND CONTRACTS ..................................................................................... - 10 COMPETITIVE FUNDING ...................................................................................................................... - 10 RESEARCH PUBLICATIONS ...................................................................................................... - 12 PEER REVIEWED PUBLICATIONS ........................................................................................................... - 12 APPROVED RESEARCH............................................................................................................ - 20 AWARDS AND PRIZES............................................................................................................. - 45 COMMUNITY AND PROFESSIONAL ACTIVITIES ........................................................................ - 46 MAJOR PARTNERS AND LINKAGES.......................................................................................... - 47 CONTACT DETAILS.................................................................................................................. - 48 -
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Regional Clinical Practice Research Centre
Message from the Director of the Centre
2012 saw the finalisation of plans for the $2.255M HWA funded Nambour Academic
and Research Centre (NARC). Upon the completion of the NARC in mid 2013 the
Regional Clinical Practice Research Centre will share space with the Sunshine
Coast Hospital & Health Service Research Office, the University of the Sunshine
Coast and the Sunshine Coast Clinical School.
Architects impression – Nambour Academic and Research Centre
In 2012 the Research Board and Health Service restructured the Clinical Trials team
and processes. Combined with the opening of the NARC, this will enable an increase
in clinical trials and conduct of original clinical research studies.
The Centre experienced a significant increase in research activity throughout 2012
which is evidenced by the below snapshot.
Activity
Approved Grants
Approved Research
Publications
2011 Total
$39,000
40 projects
25
2012 Total
$110,000 (approx)
113 projects
67
Associate Professor Steve Coverdale
Acting Director, Regional Clinical Practice Research Centre
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Centre Membership
Professional, Academic and Honorary Staff
Title
First Name
Last Name
Prof
Dario
SORRENTINO
A/Prof
Steven
COVERDALE
A/Prof
Geoffrey
HAWSON
A/Prof
Peter T
NASH
A/Prof
Johan
VAN DEN BOGAERDE
A/Prof
Edward
WEAVER
Dr
Aymen
AL-TIMIMI
Dr
Chris
ANSTEY
Dr
Lovell
ASEERVATHAM
Dr
Jennifer
BROOM
Dr
Victoria
CAMPBELL
Dr
Christopher H
CANTOR
Dr
James
CHALLEN
Dr
Anthony
CHAN
Dr
Keat
CHOONG
Dr
Carolyn
CLARK
Dr
James
CRAIG
UQ Appointment and Level , showing
School/Institute
Conjoint - Professor
School of Medicine, Sunshine Coast Clinical School
Conjoint - Associate Professor
School of Medicine, Sunshine Coast Clinical School
Academic Title-Associate Professor
School of Medicine, Sunshine Coast Clinical School
Academic Title-Associate Professor
School of Medicine, Sunshine Coast Clinical School
Academic Title-Associate Professor
School of Medicine, Sunshine Coast Clinical School
Conjoint - Associate Professor
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Conjoint - Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
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Hospital Appointment
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Private Practice
Psychiatry
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Title
First Name
Last Name
Dr
Michelle
CRONK
Dr
Simon
DUPRE
Dr
Roger
FAINT
Dr
Gordon
FAULDS
Dr
Christine
FAWCETT
Dr
Peter
GARRETT
Dr
Nicholas
GRAY
Dr
Nanu
GREWAL
Dr
David A
GRIEVE
Dr
Rohan
GRIMLEY
Dr
Pamela
HUDSON-JESSOP
Dr
Mark
JOHNSON
Dr
Clara I J
JONSSON
Dr
Mark D
LANDY
Dr
Peter
LARSEN
Dr
Chris
LAWSON
Dr
Christopher W
LILLEY
Dr
Jason
LINDEMAN
Dr
Jeremy E H
LONG
Dr
Kumaradevan
MAHADEVAN
UQ Appointment and Level , showing
School/Institute
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Conjoint - Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Conjoint - Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
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Hospital Appointment
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
General Practice
Buderim Marketplace Medical Centre
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
General Practice – Discipline Supervisor
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Title
First Name
Last Name
Dr
Matthew C
MARRINAN
Dr
Craig
MASKIELL
Dr
Tim
MCNAMARA
Dr
Roger M J
MORRIS
Dr
Glynn
MOSELEY
Dr
Ian W
MOTTARELLY
Dr
Timothy R
NATHAN
Dr
Kenneth
NG
Dr
David W
NICHOLLS
Dr
Stella
ROWLANDS
Dr
Michael J
SCHOEMAN
Dr
Carl B
SCOTT
Dr
Dawid
SMALBERGER
Dr
Robyn M
TAIKATO
Dr
James
TUNGGAL
Dr
Yusuke
UENO-DEWHIRST
Dr
Anne-Marie
WELSH
Dr
Helen
WESTON
Dr
Alexander
WILLSON
Dr
Joseph C H
WONG
UQ Appointment and Level , showing
School/Institute
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Adjunct Appointment – Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer - School of Medicine,
Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
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Hospital Appointment
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
General Practice
Medicine on 2nd
General Practice
Nambour Clinic
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Private Practice
Rheumatology
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Title
First Name
Last Name
Dr
Drasko
ZEMBIC
Dr
Matthew
AMODEO
Dr
Raguraman
JANAKIRAMAN
Dr
Vikram A
MASURKAR
Dr
Debra J
TELLAM
Dr
Prathmesh
CONTRACTOR
Dr
Brunhilde
DAVIS
Dr
Thushara
DISSANAYAKE
Dr
Elise
GILBERTSON
Dr
Anita
HARRIS
Dr
Rose
IRON
Dr
Leon
KITIPORNCHAI
Dr
Lidia
KOVAL
Dr
Kelvin
LARWOOD
Dr
Kim
LATENDRESSE
Dr
Julie
LEE
Dr
Matthew
LEE-ARCHER
Dr
Ashish K
PANIGRAHI
Dr
Haseeb A
QURESHI
Dr
Jonathan
ROBERTSON
UQ Appointment and Level , showing
School/Institute
Academic Title-Senior Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title - Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title - Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title - Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title - Lecturer
School of Medicine, Sunshine Coast Clinical School
Registrar - Associate Lecturer
School of Medicine, Sunshine Coast Clinical School
Registrar - Associate Lecturer
School of Medicine, Sunshine Coast Clinical School
Registrar - Associate Lecturer
School of Medicine, Sunshine Coast Clinical School
Registrar - Associate Lecturer
School of Medicine, Sunshine Coast Clinical School
Registrar - Associate Lecturer
School of Medicine, Sunshine Coast Clinical School
Registrar - Associate Lecturer
School of Medicine, Sunshine Coast Clinical School
Registrar - Associate Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title - Associate Lecturer
School of Medicine, Sunshine Coast Clinical School
Registrar - Associate Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title - Associate Lecturer
School of Medicine, Sunshine Coast Clinical School
Registrar - Associate Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title - Associate Lecturer
School of Medicine, Sunshine Coast Clinical School
Registrar - Associate Lecturer
School of Medicine, Sunshine Coast Clinical School
Academic Title - Associate Lecturer
School of Medicine, Sunshine Coast Clinical School
Registrar - Associate Lecturer
School of Medicine, Sunshine Coast Clinical School
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Hospital Appointment
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Title
First Name
Last Name
Dr
Euan
ROBINSON
Dr
Timothy J
SMITH
Dr
Deepak L
VARDESH
Dr
Antony J
WINKEL
Mr
Robert
PENFOLD
UQ Appointment and Level , showing
School/Institute
Registrar - Associate Lecturer
School of Medicine, Sunshine Coast Clinical School
Registrar - Associate Lecturer
School of Medicine, Sunshine Coast Clinical School
Registrar - Associate Lecturer
School of Medicine, Sunshine Coast Clinical School
Registrar - Associate Lecturer
School of Medicine, Sunshine Coast Clinical School
Industry Fellow - Clinical Librarian
School of Medicine, Sunshine Coast Clinical School
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Hospital Appointment
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Sunshine Coast Health Service District Nambour General Hospital
Research Grants and Contracts
Competitive Funding
Years of
funding
Total
funding
($)
Amount ($)
received in
2012
Grant title
Granting agency / scheme
Names of chief investigators
UQ Admin
Unit
2
$64,000
$34,500
Wishlist (Sunshine Coast)
Prof Dario Sorrentino
University of
Queensland
1
$21,764
Approved
in 2012
Wishlist (Sunshine Coast)
Dr Victoria Campbell
Dr Nicholas Gray
N/A
1
$15,600
Approved
in 2012
Human Microbial gene expression
in early Crohn’s disease: clues to
aetiology and pathogenesis
The evaluation of midkine levels in
patients with kidney disease: a pilot
study
Telephone versus office outpatient
trial
Wishlist (Sunshine Coast)
Dr Nicholas Gray
N/A
2
$13,837
Approved
in 2012
Wishlist (Sunshine Coast)
$10,000
Approved
in 2012
Wishlist (Sunshine Coast)
Associate Professor Steven
Coverdale
Dr Stella Rowlands
Dr Jeremy Long
N/A
1
N/A
1
$5,000
Approved
in 2012
Is teaching clinical documentation
on the job adequately supporting
the delivery of clinical care in 2013
Prevalence of IgE to galactose-a
1,3 galactose in patients with
metastatic colorectal cancer in the
Sunshine Coast Health Service
District
Step Forward Program: Improving
efficiency of care
Wishlist (Sunshine Coast)
Dr Christine Fawcett
N/A
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Years of
funding
Total
funding
($)
Amount ($)
received in
2012
Grant title
Granting agency / scheme
Names of chief investigators
UQ Admin
Unit
1
$5,000
Approved
in 2012
Wishlist (Sunshine Coast)
Ms Suzanne Ryan
Dr David Grieve
N/A
1
$4,000
Approved
in 2012
Clinical handover is a vital aspect of
continuity of patient care. Much of
the focus of recent research has
explored communication practices
between nursing and medical staff
at the change of shift. This project
aims to establish the evidence base
for delineating components of the
clinical handover during preparation
and transfer of a patient to the
operative environment.
Predictors of end-stage kidney
disease and mortality among
patients referred to nephrology
outpatient clinics
Wishlist (Sunshine Coast)
Dr Christine Sammartino
Dr Nicholas Gray
N/A
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Research Publications
Peer Reviewed Publications
Journal (peer reviewed)
A case of bilateral lower cranial nerve palsies after base of skull trauma With complex management issues case report and review of the
literature.
Lehn, Alexander Christoph, Lettieri, Jennie and Grimley, Rohan
Neurologist (2012), 18 3: 152-154.
A multicentre, randomized, double-blinded, placebo-controlled Phase III study to investigate EXtending the time for Thrombolysis in
Emergency Neurological Deficits.
Ma, Henry, Parsons, Mark W., Christensen, Soren, Campbell, Bruce C. V., Churilov, Leonid, Connelly, Alan, Yan, Bernard, Bladin, Chris, Phan,
Than, Barber, Alan P., Read, Stephen, Hankey, Graeme J., Markus, Romesh, Wijeratne, Tissa, Grimley, R., Mahant, N., Kleinig, Tim, Sturm, John,
Lee, A., Blacker, D., Gerraty, Richard, Krause, M., Desmond, P. M., McBride, S. J., Carey, Leanne, Howells, David W., Hsu, C. Y., Davis, Stephen
M. and Donnan, Geoffrey A.
International Journal of Stroke (2012), 7 1: 74-80.
A randomised controlled trial of Heparin versus EthAnol Lock THerapY for the prevention of Catheter Associated infecTion in
Haemodialysis patients – the HEALTHY-CATH trial.
Jennifer K Broom, Rathika Krishnasamy, Carmel M Hawley, E Geoffrey Playford and David W Johnson.
BMC Nephrology 2012 Nov 2;13:146.
Anti-TNFs for prevention of postoperative recurrence of Crohn's disease: A broken record?.
Sorrentino, Dario
Inflammatory Bowel Diseases (2012), 18 9: 1624-1625.
Atypical fractures associated with bisphosphonate use post renal transplantation.
Burke MT, Hollett PR, Gray NA.
Nephrology 2012; 17 (Supp 1): 1-4
Bringing top end endoscopy to regional Australia: hurdles and benefits.
Van den Bogaerde J., Sorrentino D.
Diagn Ther Endosc. 2012;2012:347202
Carcinoid tumour management in haemodialysis: a case report.
Burke MT, Gray NA.
Nephrology 2012; 17(2): 198
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Clinical remission after stopping infliximab in Crohn's Disease: Is all that glitters true gold?.
Sorrentino, Dario and Radford-Smith, Graham
Gastroenterology (2012), 142 5: E17-E17.
Coccidioidomycosis in returned immunocompetent Australian Travellers.
Subedi Shradha, Broom Jennifer, Sowden David, Bint Michael and Caffery Michael.
Internal Medicine Journal. 2012 Aug;42(8):940-3
Computed tomography-based sizing recommendations for transcatheter aortic valve replacement with balloon-expandable valves:
Comparison with transesophageal echocardiography and rationale for implementation in a prospective trial
Willson, Alexander B.; Webb, John G.; Freeman, Melanie; et al.
Journal of Cardiovascular Computed Tomography Volume: 6 Issue: 6 Pages: 406-414 Published: NOV-DEC 2012
Dialysis in public and private hospitals in Queensland.
Gray NA, Dent H, McDonald SP.
Internal Medicine Journal 2012; 42(8): 887-893
Early diagnosis and treatment of postoperative endoscopic recurrence of Crohn's disease: partial benefit by infliximab--a pilot study.
Sorrentino D, Terrosu G, Paviotti A, Geraci M, Avellini C, Zoli G, Fries W, Danese S, Occhipinti P, Croatto T, Zarifi D.
Dig Dis Sci. 2012 May;57(5):1341-8
Impact of tactile dysfunction on upper-limb motor performance in children with unilateral cerebral palsy.
Auld, Megan, Boyd, Roslyn, Moseley, G. Lorimer, Ware, Robert S. and Johnston, Leanne M.
Archives of Physical Medicine And Rehabilitation (2012), 93 4: 696-702.
Immunogenicity, safety and efficacy of abatacept administered subcutaneously with or without background methotrexate in patients with
rheumatoid arthritis: Results from accompany, a phase III study.
Nash P, Nayiager S, Genovese MC, Kivitz AJ, Oelke K, Ludivico C, Palmer W, Rodriguez C, Delaet I, Elegbe A, Corbo M.
Arthritis Care Res (Hoboken). 2012 Oct 24. doi: 10.1002/acr.21876. [Epub ahead of print]
Intensive Enough?.
Campbell, Victoria
New England Journal of Medicine (2012), 366 22: 2124-2125.
Living donor registries are needed.
Sammartino C, Clark C, Gray N.
BMJ 2012; 344: e2727
Long Term Survival in HIV positive patients with up to 15 years of Antiretroviral Therapy.
McManus H, O’Connor CC, Boyd M, Broom J, Russell D, Watson K, Roth N, Read PJ, Petoumenos K, Law M on Behalf of the Australian HIV
Observational Database (AHOD)
PLoS One. 2012;7(11)
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Moving from Viral Suppression to Comprehensive Patient-Centered Care: The High Prevalence of Comorbid Conditions and Health Risk
Factors in HIV-1-Infected Patients in Australia.
Broom J, Sowden, D, Williams M, Taing K, Morwood K, and McGill K.
J Int Assoc Physicians AIDS Care (Chic). 2012 Mar-Apr;11(2):109-14.
Mucosal healing and clinical remission in inflammatory bowel diseases: Are we missing something here?
Sorrentino D.
Inflamm Bowel Dis. 2012 Apr 19 doi: 10.1002/ibd.22999.
N-terminal pro-brain natriuretic peptide in a novel screening algorithm for pulmonary arterial hypertension in systemic sclerosis: a casecontrol study.
Thakkar V, Stevens WM, Prior D, Moore OA, Byron J, Liew D, Patterson K, Hissaria P, Roddy J, Zochling J, Sahhar J, Nash P, Tymms K,
Celermajer D, Gabbay E, Youssef P, Proudman SM, Nikpour M.
Arthritis Res Ther. 2012 Jun 12;14(3):R143. doi: 10.1186/ar3876.
Percutaneous Aortic Valve Replacement
Toggweiler, Stefan; Gurvitch, Ronen; Leipsic, Jonathon; et al. (Alexander Willson)
Journal of the American College of Cardiology Volume: 59 Issue: 2 Pages: 113-118 Published: JAN 10 2012
Predictive value according to location of incidental focal colorectal fluorodeoxyglucose uptake on positron emission tomography scans.
Lee, J. C., Hartnett, G. F. and Ravi Kumar, A. S.
Colorectal Disease (2012), 14 5: 642-643.
Prevalence, correlates and clinical usefulness of antibodies to RNA polymerase III in systemic sclerosis: a cross-sectional analysis of
data from an Australian cohort.
Nikpour M, Hissaria P, Byron J, Sahhar J, Micallef M, Paspaliaris W, Roddy J, Nash P, Sturgess A, Proudman S, Stevens W
Arthritis Res Ther. 2011;13(6):R211. doi: 10.1186/ar3544. Epub 2011 Dec 22.
Renal replacement therapy in rural and urban Australia.
Gray NA, Dent H, McDonald SP.
Nephrol Dial Transplant 2012; 27(5): 2069-2076
Recommendations for the treatment of Crohn's disease with tumor necrosis factor antagonists: An expert consensus report.
Feagan, Brian G., Lemann, Marc, Befrits, Ragnar, Connell, William, D'Haens, Geert, Ghosh, Subrata, Michetti, Pierre, Ochsenkuhn, Thomas,
Panaccione, Remo, Schreiber, Stefan, Silverberg, Mark, Sorrentino, Dario, van der Woude, C. Janneke, Vermeire, Severine and Rutgeerts, Paul
Inflammatory Bowel Diseases (2012), 18 1: 152-160.
Recommendations for the treatment of ulcerative colitis with infliximab: A gastroenterology expert group consensus.
Reinisch, Walter, Van Assche, Gert, Befrits, Ragnar, Connell, William, D'Haens, Geert, Ghosh, Subrata, Michetti, Pierre, Ochsenkuhn, Thomas,
Panaccione, Remo, Schreiber, Stefan, Silverberg, Mark S., Sorrentino, Dario, van der Woude, Janneke, Vermeire, Séverine and Panes, Julian
Journal of Crohns and Colitis (2012), 6 2: 248-258.
Reproducibility of tactile assessments for children with unilateral cerebral palsy.
Auld, Megan Louise, Ware, Robert S., Boyd, Roslyn Nancy, Moseley, G.Lorimer and Johnston, Leanne Marie
Physical and Occupational Therapy in Paediatrics (2012), 32 2: 151-166.
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Sex Differences in Mortality After Transcatheter Aortic Valve Replacement for Severe Aortic Stenosis
Humphries, Karin H.; Toggweiler, Stefan; Rodes-Cabau, Josep; et al. (Alexander Willson)
Journal of the American College of Cardiology Volume: 60 Issue: 10 Pages: 882-886 Published: SEP 4 2012
Structural Integrity of Balloon-Expandable Stents After Transcatheter Aortic Valve Replacement Assessment by Multidetector Computed
Tomography
Willson, Alexander B.; Webb, John G.; Gurvitch, Ronen; et al.
Jacc-Cardiovascular Interventions Volume: 5 Issue: 5 Pages: 525-532 Published: MAY 2012
Tactile function in children with unilateral cerebral palsy compared to typically developing children.
Auld, Megan Louise, Boyd, Roslyn, Moseley, G. Lorimer, Ware, Robert and Johnston, Leanne Marie
Disability and Rehabilitation (2012), 34 17: 1488-1494.
The development of candidate composite disease activity and responder indices for psoriatic arthritis.
Helliwell, P.S., FitzGerald, O., Fransen, J., Gladman, D.D., Kreuger, G.G., Callis-Duffin, K., McHugh, N., Mease, P.J., Strand, V., Waxman, R.,
Azevedo, V.F., Ostos, A.B., Carneiro, S, Cauli, A., Espinoza, L.R., Flynn, J.A., Hassan, N., Healy, P., Kerzberg, E.M., Lee, Y.J., Lubrano, E.,
Marchesoni, A., Marzo-Ortega, H., Porru, G., Moreta, E.G., Nash, P., Raffayova, H., Ranza, R., Raychaudhuri, S.P., Roussou, E., Scarpa, R., Song,
Y., Soriano, E., Tak, P.P., Ujfalussy, I., de Vlam, K. and Walsh, J.A.
(2012) Annals of the Rheumatic Diseases, in press
The race for mainstream gastrointestinal endoscopy: frontrunners.
Seltenreich, H., Van den Bogaerde, J. and Sorrentino, D.
Expert Review of Gastroenterology and Hepatology (2012), 6 4: 467-479.
The role of magnetic resonance imaging in detecting intestinal fibrosis in Crohn's disease.
Fiorino, Gionata, Cesarini, Monica, Malesci, Alberto, Danese, Silvio and Sorrentino, Dario
Current Drug Targets (2012), 13 10: 1273-1279.
The use of Key Performance Indicators to benchmark individual clinic performance in the management of a complex chronic infectious
disease.
Kelly M, Broom J, Young S.
Med J Aust. 2012 Sep 17;197(6):330-1
Tofacitinib or adalimumab versus placebo in rheumatoid arthritis.
van Vollenhoven RF, Fleischmann R, Cohen S, Lee EB, GarcÃa Meijide JA, Wagner S, Forejtova S, Zwillich SH, Gruben D, Koncz T, Wallenstein
GV, Krishnaswami S, Bradley JD, Wilkinson B; ORAL Standard Investigators (Peter Nash)
N Engl J Med. 2012 Aug 9;367(6):508-19. doi: 10.1056/NEJMoa1112072.
Transcatheter Aortic Valve Replacement Outcomes of Patients With Moderate or Severe Mitral Regurgitation
Toggweiler, Stefan; Boone, Robert H.; Rodes-Cabau, Josep; et al. (Alexander Willson)
Journal of the American College of Cardiology Volume: 59 Issue: 23 Pages: 2068-2074 Published: JUN 5 2012
- 15 -
Transcatheter Aortic Valve Replacement With the St. Jude Medical Portico Valve First-in-Human Experience
Willson, Alexander B.; Rodes-Cabau, Josep; Wood, David A.; et al.
Journal of the American College of Cardiology Volume: 60 Issue: 7 Pages: 581-586 Published: AUG 14 2012
Transcatheter Valve-In-Valve Implantation for Failed Balloon-Expandable Transcatheter Aortic Valves
Toggweiler, Stefan; Wood, David A.; Rodes-Cabau, Josep; et al. (Alexander Willson)
Jacc-Cardiovascular Interventions Volume: 5 Issue: 5 Pages: 571-577 Published: MAY 2012
Book chapter
Anti-TNF’s for prevention of postoperative recurrence of Crohn’s disease: The state of the art.
Sorrentino D. Buckton S.
From: Medrano Acevedo AD and Fajardo Gaitan M. Editors: Infliximab: Pharmacology, Uses and Limitations. Nova Science Publishers, Inc.,
Hauppauge, NY, USA 2012 pp 135-150.
Diagnosis and assessment of Crohn’s disease.
Hilton D, Marr K, Sandford A, Van den Bogaerde J. Sorrentino D.
From: LeBlanc, J.G., de Moreno de LeBlanc, A. Editors: Crohn’s Disease: Etiology, Diagnosis and Treatment Options, Nova Science Publishers,
Inc., Hauppauge, NY, USA 2012 pp 39-57
Innovative Uses and Emerging Technologies in Endoscopy.
Van den Bogaerde J., Sorrentino D.
From Endoscopy / Book 2", ISBN 980-953-307-457-8. Open Science Publisher 2012
Published abstract
Analysis of plasma biomarkers potentially associated with antiangiogenic resistance in NCIC CTG/AGITG CO.20: A phase III randomized
trial of cetuximab (CET) plus either brivanib alaninate (BRIV) or placebo in patients (pts) with chemotherapy refractory, k-RAS wild-type
(WT), metastatic colorectal carcinoma (mCRC).
Jeremy David Shapiro, Lillian L. Siu, Christopher J O'Callaghan, John Raymond Zalcberg, Malcolm J. Moore, Timothy Jay Price, Catherine Doyle,
John Simes, Brian Peter Findlay, Michelle F. Cronk, Asif Shaikh, Warren Lance Joubert, Benoit Samson, Antonino Bonaventura, Craig Underhill,
David Wyld, Ian B. Walters, Penny Phillips, Dongsheng Tu, Derek J. Jonker, and NCIC CTG AND AGITG
Journal of Clinical Oncology, 2012 ASCO Annual Meeting Proceedings (Post-Meeting Edition). Vol 30, No 15_suppl (May 20 Supplement), 2012:
TPS4137
Anti-glomerular basement membrane disease occurring during pregnancy.
O’Shea S, Francis R, Sammartino C, Ratanjee S, Gray N.
Nephrology 2012; 17(Sup 2): A44
Does prescribed and delivered haemodialysis treatment time differ?
Noble E, Sullivan M, Gray NA.
Nephrology 2012; 17(Sup 2): A41
FIRST-IN-MAN TRANSFEMORAL TRANSCATHETER AORTIC VALVE REPLACEMENT WITH THE 29MM EDWARDS SAPIEN XT VALVE
Freeman, M.; Rodes-Cabau, J.; Alcazar, M. Urena; et al. (Alexander Willson)
Canadian Journal of Cardiology Volume: 28 Issue: 5 Pages: S252-S253 Published: SEP-OCT 2012
- 16 -
PAN1: A randomized phase II study evaluating potential predictive biomarkers in the treatment of metastatic pancreatic cancer.
Yu Jo Chua, Christos Stelios Karapetis, Craig Underhill, Louise M. Nott, David Goldstein, Michelle F. Cronk, Val Gebski, Nicole Wong, Katrin Marie
Sjoquist, Andrew Victor Biankin and Australasian Gastrointestinal Trials Group (AGITG)
Journal of Clinical Oncology, 2012 ASCO Annual Meeting Proceedings (Post-Meeting Edition). Vol 30, No 15_suppl (May 20 Supplement), 2012:
TPS4137
Patient information about options for treatment (PINOT) follow up study: answering important questions in home dialysis and
conservative care.
Morton R, Connolly M, Snelling P, Gray N, Webster A, Howard K, McGeechan K, Kerr P.
Nephrology 2012; 17(Sup 2): A99
Peritoneal dialysis in rural Australia.
Gray NA, Grace B, McDonald SP.
Nephrology 2012; 17(Sup 2): A136
Safety profile of subcutaneous abatacept focusing On clinically relevant events in patients with rheumatoid arthritis and up to 4.5 years of
exposure
Alten, Rieke, Kaine, Jeffrey L., Keystone, Edward, Nash, Peter T., Delaet, Ingrid, Qi, Keqin and Genovese, Mark C.
In: Rheumatology 2012 Abstracts: Poster Viewing II. Annual Meeting of the British-Society-for-Rheumatology, Glasgow, Scotland, (127-128). 1 - 3
May 2012
THREE-DIMENSIONAL AORTIC ANNULAR ASSESSMENT BY MULTIDETECTOR COMPUTED TOMOGRAPHY PREDICTS MODERATE OR
SEVERE PARAVALVULAR REGURGITATION AFTER TRANSCATHETER AORTIC VALVE REPLACEMENT: A MULTICENTER
RETROSPECTIVE ANALYSIS
Willson, Alex; Webb, John; LaBounty, Troy; et al.
Journal of the American College of Cardiology Volume: 59 Issue: 13 Pages: E325-E325 Published: MAR 27 2012
Transcatheter Aortic Valve Replacement with a New Self-expanding Percutaneous Heart Valve and Motorized Delivery System
Binder, Ronald; Schaefer, Ulrich; Kuck, Karl-Heinz; et al. (Alexander Willson)
Journal of the American College of Cardiology Volume: 60 Issue: 17 Pages: B233-B233 Published: OCT 23 2012
Conference Paper (peer reviewed)
A Longitudinal Study of Prognostic Factors in Patients with Early RA Providing Direction for Future Clinical Treatment- Predict Study.
Bird P, Nicholls D, de Jager J, Griffiths H, Roberts L, Tymms K, Zochling J, Arnold M, Littlejohn G.
In: ACR/ARHP Annual Meeting (2012) Washington, D.C., November 9-14, 2012
A retrospective chart review of Mabthera (rituximab) for rheumatoid arthritis in Australian rheumatology practice.
Nicholls, D.
Australian Rheumatology Association Annual Scientific Meeting Canberra 2012 – Clinical Free Paper
A survey study of methotrexate use by rheumatologists and their patients with rheumatoid arthritis.
Nash, Peter and Nicholls, Dave
In: Abstracts of the American College of Rheumatology & Association of Rheumatology Health Professionals, Annual Scientific Meeting (2012).
Annual Scientific Meeting of the American-College-of-Rheumatology (ACR) and Association-of-Rheumatology-Health-Professionals (ARHP),
Washington, DC, United States, (S670-S670). 9-14 November 2012.
- 17 -
Australian psoriasis treatment goals project.
Foley, P., Baker, C., Cooper, A., Chan, J., Fischer, G., Soyer, H. P., Shumack, S., Sidhu, S., Wu, J., Nash, P., Rawlin, M. and Radulski, B.
In: The Australasian College of Dermatologists 45th Annual Scientific Meeting (2012). The Australasian College of Dermatologists 45th Annual
Scientific Meeting, Brisbane, Australia, (18-19). 20-23 May 2012.
DAS in Australian RA patients inversely relates to socioeconomic status.
Arnold M, Franklyn K, Scott J, Bird P, de Jager J, Griffiths H, Littlejohn G, Nicholls D, Roberts L, Tymms K, Zochling J.
In: Australian Rheumatology Association Annual Scientific Meeting Canberra 2012
Efficacy, safety and pharmacokinetics of subcutaneous abatacept in patients with rheumatoid arthritis, with or without an intravenous
loading dose.
Nash, Peter T., Ludivico, Charles L., Delaet, Ingrid, Qi, Keqin, Murthy, Bindu, Corbo, Michael and Kaine, Jeffrey L.
In: Rheumatology 2012 Abstracts (2012). Annual Meeting of the British-Society-for-Rheumatology, Glasgow Scotland, (iii133-iii134). May 1-3 2012.
Efficacy, safety and pharmacokinetics of subcutaneous abatacept in patients with rheumatoid arthritis, with or without an intravenous
loading dose.
Nash, P., Ludivico, C., Delaet, I., Qi, K., Murthy, B., Corbo, M. and Kaine, J.
In: Australian Rheumatology Association in conjunction with Rheumatology Health Professionals 53rd Annual Scientific Meeting (2012). Australian
Rheumatology Association in Conjunction with Rheumatology Health Professionals 53rd Annual Scientific Meeting, Canberra, Australia, (12-12). 1215 May 2012.
Impact of etanercept-methotrexate therapy on patient-reported outcomes in moderately active rheumatoid arthritis: Australian results
from the induction period of preserve trial.
Nash, P., Hall, S., Bird, P., Bananis, E., Koenig, A., Szumski, A., Jones, H., Kotak, S., Witcombe, D. and Thirunavukkarasu, K.
In: Australian Rheumatology Association in conjunction with Rheumatology Health Professionals 53rd Annual Scientific Meeting (2012). Australian
Rheumatology Association in conjunction with Rheumatology Health Professionals 53rd Annual Scientific Meeting, Canberra, ACT, Australia, (1213). 12-15 May 2012.
Long-term safety of tocilizumab in rheumatoid arthritis clinical trials.
Taylor, A., Nash, P., Hall, S., Jones, G., Youssef, P., Porter-Brown, B., Thompson, L. and Genovese, M.
In: Special Issue: Australian Rheumatology Association in conjunction with Rheumatology Health Professionals 53rd Annual Scientific Meeting
(2012). 53rd Annual Scientific Meeting of the Australian Rheumatology Association in conjunction with Rheumatology Health Professionals,
Canberra ACT, Australia, (14-14). 12-15 May 2012.
Matrix: Mapping Australian Treatment Reality Involving Methotrexate (mtx), a Survey Study of Rheumatologists and Their Patients with
Rheumatoid Arthritis (ra).
Nash, P. and Nicholls, D.
In: Special Issue: Australian Rheumatology Association in conjunction with Rheumatology Health Professionals 53rd Annual Scientific Meeting
(2012). 53rd Annual Scientific Meeting of the Australian Rheumatology Association in conjunction with Rheumatology Health Professionals,
Canberra ACT, Australia, (13-13). 12-15 May 2012.
Medication Choices and Medication Survival in a National Multi-centre Community Based Rheumatoid Arthritis Cohort
Roberts L, Tymms K, de Jager J, Littlejohn G, Griffiths H, Nicholls D, Bird P, Hill J, McCloud P, Scott J, Zochling J, on behalf of the OPAL
consortium.
In: 2012 ACR/ARHP Annual Meeting, Washington, D.C., November 9-14, 2012
- 18 -
Patient information about options for treatment (PINOT) follow up study: answering important questions in home dialysis and
conservative care.
Morton, R., Connolly, M., Snelling, P., Gray, N., Webster, A., Howard, K., McGeechan, K. and Kerr, P.
In: Special Issue: Abstracts of the 48th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (2012). 48th Annual
Scientific Meeting of the Australian and New Zealand Society of Nephrology, Auckland, (53-53). 27-29 August 2012.
Prolonged exposure to subcutaneous and intravenous abatacept in patients with rheumatoid arthritis does not affect rates of infection,
malignancy and autoimmune events: results from pooled clinical trial data.
Genovese, M. C., Hochberg, M. C., Cohen, R. B., Weinblatt, M. E., Kaine, J., Keystone, E., Nash, P., Delaet, I. and Alten, R.
In: Abstracts of the American College of Rheumatology & Association of Rheumatology Health Professionals (2012), Annual Scientific Meeting.
Annual Scientific Meeting of the American-College-of-Rheumatology (ACR) and Association-of-Rheumatology-Health-Professionals (ARHP),
Washington, DC, United States, (S725-S725). 9-14 November 2012.
Subcutaneous abatacept: long-term data from the Acquire Trial.
Genovese, M. C., Pacheco-Tena, C., Covarrubias, A., Leon, G., Mysler, E., Keiserman, M., Valente, R., Nash, P., Simon-Campos, J. A., Box, J.,
Legerton, C., III, Nasonov, E., Durez, P., Delaet, I. and Alten, R.
In: Abstracts of the American College of Rheumatology & Association of Rheumatology Health Professionals, Annual Scientific Meeting (2012).
Annual Scientific Meeting of the American-College-of-Rheumatology (ACR) and Association-of-Rheumatology-Health-Professionals (ARHP),
Washington, DC, United States, (S201-S201). 9-14 November 2012.
Subcutaneous abatacept versus intravenous abatacept in patients with rheumatoid arthritis: Long-term data from the acquire trial.
Genovese, Mark C., Cobos, Arturo, Leon, Gustavo, Mysler, Eduardo F., Keiserman, Mauro W., Valente, Robert M., Nash, Peter T., Campos, J.
Abraham Simon, Porawska, Wiewlsawa, Box, Jane H., Legerton, Clarence W., Nasonov, Evgeny L., Durez, Patrick, Pappu, Ramesh, Delaet, Ingrid,
Teng, Julie and Alten, Rieke
In: Rheumatology 2012 Abstracts: Poster Viewing II. Annual Meeting of the British-Society-for-Rheumatology, Glasgow, Scotland, (128-129). 1 - 3
May 2012.
Safety profile of subcutaneous abatacept focusing On clinically relevant events in patients with rheumatoid arthritis and up to 4.5 years of
exposure.
Alten, Rieke, Kaine, Jeffrey L., Keystone, Edward, Nash, Peter T., Delaet, Ingrid, Qi, Keqin and Genovese, Mark C.
In: Rheumatology 2012 Abstracts: Poster Viewing II (2012). Annual Meeting of the British-Society-for-Rheumatology, Glasgow, Scotland, (127-128).
1 - 3 May 2012.
Tofacitinib (cp-690,550), an oral Janus Kinase Inhibitor: Pooled phase 3 analysis in an Australian Rheumatoid Arthritis Study Population.
Hall, S., Nash, P., Rischmueller, M., Bossingham, D., Cook, N., Kwok, K. and Thirunavukkarasu, K.
In: Special Issue: Australian Rheumatology Association in conjunction with Rheumatology Health Professionals 53rd Annual Scientific Meeting
(2012). 53rd Annual Scientific Meeting of the Australian Rheumatology Association in conjunction with Rheumatology Health Professionals,
Canberra ACT, Australia, (14-14). 12-15 May 2012.
- 19 -
Weekly subcutaneous abatacept confers comparable onset of treatment response and magnitude of efficacy improvement over 6 months
when administered with or without an intravenous abatacept loading dose.
Schiff, M., Alten, R., Weinblatt, M., Nash, P., Fleischmann, R., Durez, P., Kaine, J., Delaet, I., Kelly, S., Maldonado, M., Patel, S. and Genovese, M.
C.
In: Abstracts of the American College of Rheumatology & Association of Rheumatology Health Professionals (2012), Annual Scientific Meeting.
Annual Scientific Meeting of the American-College-of-Rheumatology (ACR) and Association-of-Rheumatology-Health-Professionals (ARHP),
Washington, DC, United States, (S1076-S1076). 9-14 November 2012.
Approved Research
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC Reference:
Trial Name:
HREC/04/QRBW/205
A phase III trial evaluating the role of ovarian function suppression and the role of Exemestane as adjuvant therapies for premenopausal
women with endorcrine responsive breast cancer: Suppression of Ovarian Function Trial (SOFT)
2006
Drug Trial
Geoffrey Hawson
Geoffrey Hawson
HREC/05/QRBW/35
IST-3: The Third International Stroke Trial (IST-3) of thrombolysis for acute ischaemic stroke. An international multi-centre, randomised,
controlled trial to investigate the safety and efficacy of treatment with intravenouse recombinant tissue plasminogen activator (rt-PA) within six
hours of onset of acute ischaemic stroke
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
Other Trial
Rohan Grimley
Rohan Grimley
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/07/QRBW/169
A phase 3, multi-centre randomized controlled trial of very early rehabilitation after stroke (AVERT)
2008
Other Trial
Rohan Grimley
Rohan Grimley
- 20 -
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/08/QPAH/168
To implement an evidence based falls clinic and determine its effectiveness in reducing falls and fall related injuries
2008
Clinical Research
Christine Fawcett
Christine Fawcett
Chris Bourke
Jeremy O'Leary
Michael Creen
HREC Reference:
Trial Name:
HREC/08/QTDD/35
CARIATIDE : Compliance of ARomatase Inhibitors AssessmenT In Daily practice through educational approach. A multi-country,
observational study to evaluate the impact of educational material on the compliance and persistence rates to adjuvant aromatase inhibitor
(AI) medication for post-menopausal women with hormone sensitive early breast cancer
2008
Trial Clinical
Michelle Cronk
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/09/QNRC/15
A double blind randomised trial of cediranib versus placebo in patients receiving paclitaxel / carboplatin chemotherapy for the treatment of
advanced or metastatic non-small cell lung cancer
2009
Drug Trial
Jeremy Long
Jeremy Long
Michelle Cronk
Geoffery Hawson
HREC/09/QNRC/17
A randomised, placebo controlled trial of oxpentifylline on haemoglobin levels in patiens with erythropoietin resistant anaemia
2009
Drug Trial
Kumar Mahadevan
Kumar Mahadevan
Nicholas Gray
Euan Nobel
Peter Hollett
- 21 -
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/09/QNRC/32
A randomised double-blind, placebo-controlled study of everolimus in combination with exemestane in the treatment of postmenopausal
women with estrogen receptor positive, locally advanced or metastatic breast cancer who are refractory to letrozole or anas
2009
Drug Trial
Michelle Cronk
Michelle Cronk
Jeremy Long
Geoffrey Hawson
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/09/QNRC/34
CONCORDANCE - Cooperative National Registry of Acute Coronary Care Guideline Adherence and Clinical Events
2009
Clinical Research
Steven Coverdale
Steven Coverdale
Matthew Marrinan
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/09/QNRC/5
A phase III randomised trial of adding niroglycerin to first line chemotherapy for advanced non-small cell lung cancer
2009
Drug Trial
Jeremy Long
Jeremy Long
Michelle Cronk
Geoffery Hawson
HREC Reference:
Trial Name:
HREC/09/QNRC/56
ACTIVE Dialysis: A clinical trial of intensive dialysis. A multi-centre unblinded randomised controlled trial to assess quality of life, clinical
outcomes and cost utility for extended versus standard duration of dialysis in patients with ESKD
2009
Other Trial
Nicholas Gray
Kumar Mahadevan
Nicholas Gray
Euan Nobel
Peter Hollett
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
- 22 -
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/09/QNRC/59
Prostatectomy Patient Education Program Research Project
2010
Health Research
Tim Nathan
Tim Nathan
Erica Mohr
Sue Torr
John Buchanan
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/09/QNRC/71
SCOT - Short Course Oncology Therapy, A study of adjuvant chemotherapy in colorectal cancer
2010
Drug Trial
Michelle Cronk
Jeremy Long
Michelle Cronk
Geoffery Hawson
HREC Reference:
Trial Name:
HREC/09/QNRC/72
A multicenter, randomized, double-blind, placebo-controlled study to evaluate cardiovascular outcomes following treatment with alogliptin in
addition to standard of care in subjects with Type 2 Diabetes and Acute Coronary Syndrome: EXAMINE
2010
Drug Trial
Steven Coverdale
Steven Coverdale
Matthew Marrinan
Steven Hamwood
Shyam Sunder
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/09/QNRC/74
Program for the assessment of clinical cancer tests (PACCT-1): Trial assigning individualized options for treatment (The TAILORx Trial) ANZ 0901
2010
Other Trial
Michelle Cronk
Jeremy Long
Michelle Cronk
Geoffery Hawson
- 23 -
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/09/QNRC/75
Multinational, randomized, double-blind, phase III study of IMC-1121B plus Docetaxel vs Placebo plus Docetaxel in previously untreated
patients with HER2-Negative, unresectable, locally-recurrent or metastatic breast cancer: TRIO-012 (ANZ 0802)
2010
Drug Trial
Michelle Cronk
Jeremy Long
Michelle Cronk
Geoffery Hawson
HREC/10/QGC/114
Prospective, Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial Comparing REMICADE® (infliximab) and Placebo in the
Prevention of Recurrence in Crohn’s Disease Patients Undergoing Surgical Resection Who Are at an Increased Risk of Recurrence
2010
Drug Trial
Dario Sorrentino
Dario Sorrentino
Hansjoerg Seltenreich
Ratna Aseervatham
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/10/QGC/129
Paroxysmal Nocturnal Haemoglobinuria (PNH) Registry
2012
Clinical Research
Christine Lambooy
Christine Lambooy
Helen Weston
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/10/QHC/41
Chronic kidney disease Queensland (CKD.QLD) database and registry
2011
Clinical Research
Nicholas Gray
Kumar Mahadevan
Nicholas Gray
Euan Nobel
Peter Hollett
Victoria Campbell
- 24 -
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/10/QHC/51
Discovery Interviews: Consumer, Carer and Clinician perceptions and experiences of Queensland Health Services
2011
Health Research
Shoni Colquist
Nicholas Gray
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/10/QNRC/29
A survey of knowledge about chronic kidney disease among nephrology outpatients
2010
Health Research
Nicholas Gray
Nicholas Gray
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/10/QPCH/126
Evaluation of the Safety and Efficacy of Short-term A-002 Treatment in Subjects with Acute Coronary Syndromes
2010
Drug Trial
Peter Larsen
Peter Larsen
Matthew Marrinan
HREC Reference:
Trial Name:
HREC/10/QPCH/165
A Double Blind Placebo Controlled Randomized Trial Of Pf-00299804 (PF-804) In Patients With Incurable Stage Iiib/Iv Non-Small Cell Lung
Cancer After Failure Of Standard Therapy For Advanced Or Metastatic Disease
2011
Drug Trial
Geoffrey Hawson
Geoffrey Hawson
Jeremy Long
Michelle Cronk
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
- 25 -
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/10/QPCH/84
Procalcitonin Guided Antibiotic Rational Decision Making in ICU Patients (ProGUARD)
2011
Other Trial
Peter Garrett
Peter Garrett
Vikram Masurkar
Chris Anstey
Gerard Joyce
Mark Landy
Victoria Campbell
Carl Scott
Chris Graves
HREC Reference:
Trial Name:
HREC/10/QRBW/238
An assessment of the difference in elapsed time to re-excision in breast conserving surgery between public and private patients in the
Nambour region
2010
Health Research
David Grieve
David Grieve
Matthew Solomon
Colin Cochrane
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/10/QRBW/302
A Multicentre, Randomised, Double-Blind, Placebo-controlled Phase Iib Study to Compare the Efficacy and Safety of Two dosing Regimens
of Intravenouse Infusions of CytoFab TM (AZD9773) in Adult Patients with severe Sepsis and/or Septic Shock
2011
Drug Trial
Peter Garrett
Peter Garrett
Vikram Masurkar
Chris Anstey
Gerard Joyce
Mark Landy
Victoria Campbell
Chris Graves
- 26 -
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/10/QRBW/341
Stroke imaging prevention and treatment (START) EXTEND: Extending the time for thrombolysis in emergency neurological deficits
2010
Drug and Device Trial
Rohan Grimley
Rohan Grimley
Mark Denhan
Antony Tampiyappa
Tomin Mooney
HREC Reference:
Trial Name:
HREC/11/QGC/134
TR701-113 A phase 3 randomised, double-blind, multicentre study comparing the efficacy and safety of intravenous to oral 6-day TR-701
Free Acid and intravenous to oral 10 day Linezolid for the treatment of acute bacterial skin and skin structure infection
2012
Drug Trial
David Sowden
David Sowden
Jennifer Broom
Keat Choong
Matthew Amodeo
Andrew Henderson
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/11/QNRC/12
Improving the practice of nutrition therapy in the critically ill: International Nutrition Survey
2011
Clinical Research
Peter Garrett
Peter Garrett
Shona McDonald
Anne Buckley
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/11/QNRC/37
Patient satisfaction with the inpatient services on the Surgival Ward at Nambour General Hospital
2011
Clinical Research
David Grieve
David Grieve
Lidia Koval
Nai Kid Lai
- 27 -
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/11/QNRC/38
Efficacy of the current plaster splinting in providing pain relief for patients with acute fractures of the ankle: a single centre experience
2011
Clinical Research
Kim Latendresse
Kim Latendresse
Lidia Koval
James Tunggal
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/11/QNRC/58
Non fixation of mesh in open inguinal hernia repair - single surgeon experience
2011
Clinical Research
David Grieve
David Grieve
Thushara Dissanayake
Nicolas Copertino
Ratna Aseervatham
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/11/QNRC/59
Patterns of injury in trauma patients requiring inter-hospital transfer from a major regional hospital to its tertiary referring facilities
2012
Clinical Research
Kevin Chan
Kevin Chan
David Grieve
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/11/QNRC/73
A prospective audit of the use and utility of diagnostic imaging in the diagnosis and management of acute appendicitis
2011
Health Research
David Grieve
David Grieve
Emily Hales
- 28 -
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/11/QNRC/9
ICU Nursing Clinical Scenario - Identifying and managing a potential organ donor
2011
Clinical Research
Susan Priebe
Susan Priebe
Jenny Jaspers
Peter Garrett
Shona McDonald
Mark Kelly
Danielle Jackson
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/11/QPAH/121
A randomised phase II study evaluating potential predictive biomarkers in the treatment of metastatic pancreatic cancer
2011
Drug Trial
Michelle Cronk
Michelle Cronk
Jeremy Long
Geoffrey Hawson
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/11/QPAH/170
A Trial in the Timing of Surgery and Adjuvant Chemotherapy for Hepatic Metastases from Colorectal Cancer
2011
Drug Trial
Michelle Cronk
Michelle Cronk
Jeremy Long
Geoffrey Hawson
Ratna Aseervatham
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/11/QPAH/300
The influence of host genetics and viral factors in chronic hepatitis C infection. ML25629
2012
Clinical Research
Andrew Sloss
Andrew Sloss
Nicola Weston
Johan van den Bogaerde
- 29 -
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/11/QPAH/335
Phase 3, Randomized, Double-blind, Placebo-controlled, Parallel-group, Multicenter Study to Evaluate the Safety and Efficacy of
Ustekinumab Induction Therapy in Subjects with Moderately to Severely Active Crohn’s Disease Who Have Failed or Are Intolerant
2012
Drug Trial
Dario Sorrentino
Dario Sorrentino
Stephanie Buckton
Andrew Sloss
Hansjorg Seltenreich
HREC/11/QPAH/336
A Phase 3, Randomized, Double-blind, Placebo-controlled, Parallel-group, Multicenter Study to Evaluate the Safety and Efficacy of
Ustekinumab Induction Therapy in Subjects with Moderately to Severely Active Crohn’s Disease
2012
Drug Trial
Dario Sorrentino
Dario Sorrentino
Stephanie Buckton
Andrew Sloss
Hansjorg Seltenreich
HREC/11/QPAH/337
A Phase 3, Randomized, Double-blind, Placebo controlled, Parallel-group, Multicenter Study to Evaluate the Safety and Efficacy of
Ustekinumab Maintenance Therapy in Subjects with Moderately to Severely Active Crohn’s Disease
2012
Drug Trial
Dario Sorrentino
Dario Sorrentino
Stephanie Buckton
Andrew Sloss
Hansjorg Seltenreich
- 30 -
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/11/QPAH/358
Bardoxolone methyl evaluation in patients with chronic kidney disease and type 2 diabetes: the occurrence of renal events
2012
Drug Trial
Nicholas Gray
Nicholas Gray
Peter Hollett
Kumar Mahadevan
Euan Noble
Victoria Campbell
HREC Reference:
Trial Name:
HREC/11/QPAH/400
A randomised, open-label study to evaluate the efficacy and safety of maraviroc (MVC) as a switch for N(t)RTI or PI/r in HIV-1 infected
individuals with stable, well-controlled plasma HIV-RNA while taking their first N(t)RTI+PI/r regimen of cART
2012
Drug Trial
David Sowden
David Sowden
Kuong Taing
Jennifer Broom
Karen Morwood
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/11/QPAH/619
A randomised blinded placebo controlled trial of hydrocortisone in critically ill patients with septic shock (ADRENAL Study)
2012
Drug Trial
Peter Garrett
Peter Garrett
Vikram Masurkar
Anne-Marie Welsh
Mark Landy
- 31 -
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/11/QPCH/14
Multicentre, Single-arm, Open Label Clinical Trial Intended to Provide Early Access to Cabazitaxel in Patients with Metastatic Hormone
Refractory Prostate Cancer Previously Treated with a Docetaxel-Containing Regimen and document safety of Cabazitaxel in
2011
Drug Trial
Michelle Cronk
Michelle Cronk
Jeremy Long
Geoffrey Hawson
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/11/QPCH/187
The tyranny of distance: exploring contributory factors for delays in transfer and intervention in multi-trauma patients
2012
Clinical Research
Martin Wullschleger
Peter Garrett
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/11/QPCH/199
Local staging of prostate cancer with 3T MRI
2012
Clinical Research
James Challen
James Challen
David O'Regan
Alex Splatt
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/11/QPCH/33
HIV in Queensland: 2011
2011
Clinical Research
Kuong Taing
Kuong Taing
David Sowden
Jennifer Broom
Karen Morwood
- 32 -
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/11/QRBW/12
Australian Stroke Clinical Register: AuSCR Queensland
2011
Clinical Research
Rohan Grimley
Rohan Grimley
Anthony Tampiyappa
Donna Rowley
Eva Salud
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/11/QRBW/148
Too much, too soon? The impact of treatment-focused genetic testing in patients newly diagnosed with breast cancer
2011
Clinical Research
David Grieve
David Grieve
Karen Crowe
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/11/QRBW/150
Prolonged Outcome Study - Renal
2011
Clinical Research
Peter Garrett
Peter Garrett
Victoria Campbell
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/11/QRBW/239
Gabapentin for taxane acute pain syndrome - a phase III randomised, placebo-controlled, crossover trial
2011
Drug Trial
Jeremy Long
Jeremy Long
Michelle Cronk
Peter Smith
Christine Cocks
- 33 -
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/11/QRBW/243
The evaluation of tele health support services for patients with head and neck cancer
2011
Health Research
Clare Burns
Karen Malcolm
HREC Reference:
Trial Name:
HREC/11/QRBW/300
Phase II study of aromatase inhibitors in women with potentially hormone responsive recurrent/metastatic gynaecological neoplasms:
PARAGON
2012
Drug Trial
Michelle Cronk
Michelle Cronk
Jeremy Long
Geoffrey Hawson
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/11/QRCH/181
Magnesium sulphate at 30 to 34 weeks gestational age: Neuroprotection Trial
2012
Drug Trial
Edward Weaver
Edward Weaver
Tom Hurley
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/11/QRCH/38
Clinical Trials Group (CTG) ICU Point Prevalence Program
2011
Clinical Research
Chris Anstey
Chris Anstey
- 34 -
HREC Reference:
Trial Name:
Commenced:
Study Type:
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Local Co-Investigators:
HREC/12/Austin/29
A randomized, double-clinded, active-controlled study of CB-183,315 in patiens with Clostridium difficile Associated Diarrhea
2012
Drug Trial
David Sowden
David Sowden
Jennifer Broom
Keat Choong
Matthew Amodeo
Andrew Henderson
Johan van den Bogaerde
HREC Reference:
Trial Name:
HREC/12/CIC/6
INTEGRATE: A randomised phase II double-blind placebo-controlled study of regorafenib in refractory advanced oesophago-gastric cancer
AOGC: Protocol Number AG0212OG
2012
Drug Trial
Michelle Cronk
Michelle Cronk
Jeremy Long
Geoffrey Hawson
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/12/QGC/24
Phase II trial of panitumumab, cisplatin and gemcitabine in biliary tract cancer
2012
Drug Trial
Michelle Cronk
Michelle Cronk
Jeremy Long
Geoffrey Hawson
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/12/QGC/47
A prospective, multi-centre observational study in pateints admitted to intensive care to estimate daily sodium balance
2012
Clinical Research
Victoria Campbell
Victoria Campbell
Peter Garrett
- 35 -
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/12/QHC/49
Final year medical students perspectives on the importance of clinical documentation in the delivery of health care in a public health hospital
2012
Health Research
Stella Rowlands
Stella Rowlands
Steven Coverdale
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/12/QNRC/22
Phase II randomised, double blind, multicentre study to assess the efficacy of AZD2281 in the treatment of patients with platinum containing
regimens. Protocol D0810C00019
2008
Drug Trial
Michelle Cronk
Michelle Cronk
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/12/QPAH/267
Carers of the Active Diaylsis Trial (CO-ACTIVE)
2012
Health Research
Nicholas Gray
Nicholas Gray
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/12/QPAH/450
Citrate anticoagulation in continuous renal replacement therapy; more time on filter, less cost?
2012
Clinical Research
David Gutierrez
David Gutierrez
Victoria Campbell
- 36 -
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/12/QPCH/14
The study of heart and renal protection - extended review
2012
Clinical Research
Nicholas Gray
Nicholas Gray
Kumar Mahadevan
Euan Noble
Victoria Campbell
Carolyn Clark
Peter Hollett
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/12/QPCH/23
Determinants and prevalence of vitamin D deficiency in HIV-infected adults living in Queensland, Australia
2012
Health Research
Karen Klassen
Jennifer Broom
HREC Reference:
Trial Name:
HREC/12/QPCH/33
What complementary and alternative medicine is taken by patients with solid tumour malignancies receiving for the first time curative intent
chemotherapy in a hospital day unit and what factors influence selection at that time
2012
Health Research
Peter Smith
Peter Smith
Jeremy Long
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/12/QPCH/72
Orthogeriatric Service-Nambour General Hospital: An audit of patients aged over 60 with fractured neck of femur - comparing two models of
care.
2012
Clinical Research
Pathiranage Abeyratne
Pathiranage Abeyratne
Vanessa Harrington
Gillian Puckeridge
Rohan Grimley
- 37 -
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/2006/QNRC/067
A phase 3 double blind placebo controlled study of maintenance pemetrexed plus best supportive care versus best supportive care
immediately following induction treatment for advanced non-small cell lung cancer
2007
Trial Clinical
Michelle Cronk
HREC/2006/QNRC/068
A randomised, multicentre phase IIIb, open label study of letrozole vs anastrozole in the adjuvant treatment of postmenopausal women with
hormone receptor and node positive breast cancer. Face Study. CFEM345D2411
2007
Drug Trial
Michelle Cronk
Michelle Cronk
HREC/2007/QNRC/001
A randomised, multi-centre, open-label, phase III study of adjuvant lapatinib, trastuzumab, their sequence and their combination in patients
with HER2ErbB2 positive primary breast cancer. The ALTTO trial.
2008
Drug Trial
Michelle Cronk
Michelle Cronk
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/2007/QNRC/005
Protocol BO20289, An international multi-centre open-label 2-arm phase III trial of adjuvant bevacizumab in triple negative breast cancer.
2007
Drug Trial
Michelle Cronk
Michelle Cronk
Geoffrey Hawson
HREC Reference:
Trial Name:
HREC/2007/QNRC/009
A phase III randomized study of brivanib alaninate (BMS-582664) in combination with cetuximab (Erbitux) versus placebo in combination with
cetuximab (Erbitux) in patients previously treated with combination chemotherapy for metastatic colorectal carcinoma.
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
Michelle Cronk
Michelle Cronk
- 38 -
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/2008/QNRC/006
A comparison of Prasugrel and Clopidogrel in Acute Coronary Syndrome (ACS) Sugjects with unstable angina/non-ST-elevation myocardial
infarction (UA/NSTEMI) who are medically managed - The TRILOGY ACS Study
2008
Drug Trial
Matthew Marrinan
Matthew Marrinan
HREC Reference:
Trial Name:
Commenced:
Study Type:
Local Chief Investigator:
Local Co-Investigators:
HREC/2008/QNRC/018
Preferences for adjuvant chemotherapy in non-small-cell lung cancer: What makes it worthwhile to patients and their doctors?
2008
Clinical Research
Michelle Cronk
Michelle Cronk
Jeremy Long
Geoffrey Hawson
Trial Name:
M10-791A Multicenter Study of the Efficacy and Safety of the Human Anti-TNF Monoclonal Antibody Adalimumabin Subjects with Axial
Spondyloarthritis
Clinical Trial
Peter Nash
David Nicholls
Study Type:
Local Investigator:
Local Co-Investigators:
Trial Name:
Study Type:
Local Investigator:
Local Co-Investigators:
Trial Name:
Study Type:
Local Investigator:
Local Co-Investigators:
Local Co-Investigators:
M10-883A Multicenter Study of the Efficacy and Safety of the Human Anti-TNF Monoclonal Antibody Adalimumab in Subjects with Peripheral
Spondyloarthritis
Clinical Trial
Peter Nash
David Nicholls
SERAPHIN OL; Study with Endothelin Receptor Antagonist in Pulmonary arterial Hypertension to Improve cliNical outcome. (Open Label) Long
term single arm open-label extension study of the SERAPHIN study, to assess the safety and tolerability of ACT-064992 in patients with
symptomatic pulmonary hypertension. AC-055-303
Clinical Trial
Peter Nash
David Nicholls
David Nicholls
- 39 -
Trial Name:
Study Type:
Local Investigator:
Local Co-Investigators:
Trial Name:
Study Type:
Local Investigator:
Local Co-Investigators:
Trial Name:
Study Type:
Local Investigator:
Local Co-Investigators:
Trial Name:
Study Type:
Local Investigator:
Local Co-Investigators:
Trial Name:
Study Type:
Local Investigator:
Local Co-Investigators:
Trial Name:
Study Type:
Local Investigator:
Local Co-Investigators:
Protocol IM133004: A Phase 2b, Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging, Multi-Center Study to Evaluate the Efficacy and
Safety of BMS-945429 subcutaneous Injection in Adults with Active Psoriatic Arthritis
Clinical Trial
Peter Nash
David Nicholls
BMS 101-226 :A Phase 3b, Randomized, Active Controlled Trial to Evaluate the Efficacy and Safety of Abatacept SC in Combination with
Methotrexate in Inducing Clinical Remission Compared to Methotrexate Monotherapy in Adults with Very Early RA
Clinical Trial
Peter Nash
David Nicholls
A PHASE 3, MULTICENTER, RANDOMIZED, DOUBLEBLIND,PLACEBO-CONTROLLED, PARALLEL-GROUPSTUDY TO EVALUATE THE
EFFICACY AND SAFETY OF APREMILAST (CC-10004) IN THE TREATMENT OFACTIVE ANKYLOSING SPONDYLITIS
Clinical Trial
Peter Nash
David Nicholls
A PHASE 3, MULTICENTER, RANDOMIZED,DOUBLE-BLIND, PLACEBO-CONTROLLED,PARALLEL-GROUP, EFFICACY AND SAFETY
STUDY OF TWO DOSES OF APREMILAST (CC-10004) IN SUBJECTS WITH ACTIVE PSORIATIC ARTHRITIS AND A QUALIFYING
PSORIASIS LESION
Clinical Trial
Peter Nash
David Nicholls
A PHASE 11B, MULTI-DOSE, MULTI-CENTER, RANDOMISED, DOUBLE BLIND, PLACEBO0CONTROLLED STUDY TO EVALUATE THE
EFFICACY AND SAFETY OF ABATACEPT VERSUS PLACEBO IN THE TREATMENT OF PSORIATIC ARTHRITIS BMS101158
Clinical Trial
Peter Nash
David Nicholls
A PHASE 111b, MULTI-CENTER, STRATIFIED, OPEN LABEL, STUDY TO EVALUATE THE IMMUNOGENICITY, STEADY STATE TROUGH
LEVEL AND SAFETY OF SUBCUTANEOUS ABATACEPT (BMS18867) IN SUBJECTS WITH RHEUMATOID ARTHRITIS ADMINISTERED
WITH OR WITHOUT BACKGROUND METHOTREXATE. PROTOCOL BMS101-173
Clinical Trial
Peter Nash
David Nicholls
- 40 -
Trial Name:
Study Type:
Local Investigator:
Local Co-Investigators:
Trial Name:
Study Type:
Local Investigator:
Local Co-Investigators:
Trial Name:
Study Type:
Local Investigator:
Local Co-Investigators:
Trial Name:
Study Type:
Local Investigator:
Local Co-Investigators:
A Multicenter, Randomized, Double-Blind, Placebo-controlled Trial of Golimumab, an Anti-TNFa Monoclonal Antibody, Administered
Intravenously, in Subjects with Active Rheumatoid Arthritis Despite Methotrexate Therapy - CNTO148ART3001
Clinical Trial
Peter Nash
David Nicholls
A prospective, multi centre randomised, double-blind, active comparator-controlled, parallel groups study comparing the fully monoclonal antiTNF α antibody Adalimumab given every second week with methotrexate given weekly and in combination of Adalimumab and methotrexate
administered over 2 years in patients with early rheumatoid arthritis (PREMIER) (Study protocol DE 013)
Clinical Trial
Peter Nash
David Nicholls
AUX-CC-867: A Phase 3b open-label, historically-controlled study to assess the safety and efficacy of two concurrent injections of AA4500 in adult
subjects with multiple Dupuytren’s contractures with palpable cords.
Clinical Trial
Peter Nash
David Nicholls
A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study Evaluating the Efficacy and Safety of Baricitinib (LY3009104) in Patients with
Moderately to Severely Active Rheumatoid Arthritis Who Have Had an Inadequate Response to Tumor Necrosis Factor Inhibitors JADW
Clinical Trial
Peter Nash
David Nicholls
Trial Name:
A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study to Evaluate the Efficacy and Safety of Baricitinib (LY3009104) in Patients with
Inadequate Response to Conventional Disease-Modifying Antirheumatic Drugs with Moderately to Severely Active Rheumatoid Arthritis JADX
Study Type:
Local Investigator:
Local Co-Investigators:
Clinical Trial
Peter Nash
David Nicholls
Trial Name:
Protocol H9B-MC-BCDT(a) A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of
Subcutaneous LY2127399 in Patients with Systemic Lupus Erythematosus (SLE) (ILLUMINATE-2)
Clinical Trial
Peter Nash
David Nicholls
Study Type:
Local Investigator:
Local Co-Investigators:
- 41 -
Study Type:
Local Investigator:
Local Co-Investigators:
Protocol H9B-MC-BCDX Phase 3b, Multicenter,Open Label Study to Evaluate the Long Term Safety and Efficacy of Subcutaneous LY2127399 in
Patients with Systemic Lupus Erythematosus (SLE)
Clinical Trial
Peter Nash
David Nicholls
Trial Name:
Study Type:
Local Investigator:
Local Co-Investigators:
BEL 116301 : Observational Study of treatment, disease activity and flare in Systemic Lupus Erythematosus(SLE) in Asia Pacific
Clinical Trial
Peter Nash
David Nicholls
Trial Name:
Protocol No. IMM 10-0107 MRI and Radiological Study of rheumatoid arthritis treated with Adalimumab and non-biological agents to assess the
impact of disease control on MRI manifestations and joint structure preservation.
Clinical Trial
Peter Nash
David Nicholls
Trial Name:
Study Type:
Local Investigator:
Local Co-Investigators:
Trial Name:
Study Type:
Local Investigator:
Local Co-Investigators:
Trial Name:
Study Type:
Local Investigator:
Local Co-Investigators:
Trial Name:
Study Type:
Local Investigator:
Local Co-Investigators:
A randomized, double-blind, placebo-controlled, multicenter study of secukinumab to demonstrate the efficacy at 24 weeks and to assess the long
term safety, tolerability and efficacy up to 2 years in patients with active psoriatic arthritis. CAIN457F2306
Clinical Trial
Peter Nash
David Nicholls
A3921069: PHASE 3, RANDOMIZED, DOUBLE-BLIND STUDY OF THE EFFICACY AND SAFETY OF 2 DOSES OF CP-690,550 COMPARED
TO METHOTREXATE IN METHOTREXATE NAIVE PATIENTS WITH RHEUMATOID ARTHRITIS
Clinical Trial
Peter Nash
David Nicholls
B3281001: A RANDOMIZED, DOUBLE-BLIND, STUDY COMPARING THE PHARMACOKINETICS AND PHARMACODYNAMICS, AND
ASSESSING THE SAFETY OF PF-05280586 AND RITUXIMAB IN SUBJECTS WITH ACTIVE RHEUMATOID ARTHRITIS ON A BACKGROUND
OF METHOTREXATE WHO HAVE HAD AN INADEQUATE RESPONSE TO ONE OR MORE TNF ANTAGONIST THERAPIES
Clinical Trial
Peter Nash
David Nicholls
- 42 -
Trial Name:
Study Type:
Local Investigator:
Local Co-Investigators:
Trial Name:
Study Type:
Local Investigator:
Local Co-Investigators:
Trial Name:
Study Type:
Local Investigator:
Local Co-Investigators:
Trial Name:
Study Type:
Local Investigator:
Local Co-Investigators:
Trial Name:
Study Type:
Local Investigator:
Local Co-Investigators:
Trial Name:
Study Type:
Local Investigator:
Local Co-Investigators:
A3921024: A Long-term, Open-label Follow-up Study of CP-690,550, a Moderately Selective Janus Kinase 3 Inhibitor, for Treatment of
Rheumatoid Arthritis
Clinical Trial
Peter Nash
David Nicholls
A Phase 3 Multicenter, Randomized, Double-blind Placebo-controlled trial of Ustekinumab, a Fully Human anti-IL-12/23p40 Monoclonal Antibody,
Administered Subcutaneously, in Subjects with Psoriatic Arthritis. CNTO127PSA3001
Clinical Trial
Peter Nash
David Nicholls
WA17044 : A Randomised, Double-Blind, International Study To Evaluate The Efficacy And Safety Of Various Re-treatment Regimens Of
Rituximab In Combination With Methotrexate In RA Patients With An Inadequate Response To Methotrexate
Clinical Trial
Peter Nash
David Nicholls
WA19926 –A Multi-center, randomized, double-blind, parallel group study of the safety, disease remission and prevention of structural joint
damage during treatment with tocilizumab (TCZ), as a monotherapy and in combination with methotrexate (MTX), versus methotrexate in patients
with early, moderate to severe rheumatoid arthritis
Clinical Trial
Peter Nash
David Nicholls
A randomized, double-blind, parallel group study of the safety and effect on clinical outcome of tocilizumab SC versus tocilizumab IV, in
combination with traditional disease modifying anti-rheumatoid arthritis drugs (DMARDs), in patients with moderate to severe active rheumatoid
arthritis. WA22762A
Clinical Trial
Peter Nash
David Nicholls
EFC11072 MOBILITY EXTENSION STUDY : A multi center, uncontrolled extension study evaluating efficacy and safety of SAR153191 on top of
DMARDs in patients with active Rheumatoid Arthritis (RA).
Clinical Trial
Peter Nash
David Nicholls
- 43 -
Trial Name:
Study Type:
Local Investigator:
Local Co-Investigators:
Trial Name:
Study Type:
Local Investigator:
Local Co-Investigators:
Trial Name:
Study Type:
Local Investigator:
Local Co-Investigators:
Trial Name:
Study Type:
Local Investigator:
Local Co-Investigators:
Trial Name:
Study Type:
Local Investigator:
Local Co-Investigators:
Trial Name:
Study Type:
Local Investigator:
Local Co-Investigators:
LTS11210 MOBILITY EXTENSION STUDY : A multi center, uncontrolled extension study evaluating efficacy and safety of SAR153191 on top of
DMARDs in patients with active Rheumatoid Arthritis (RA).
Clinical Trial
Peter Nash
David Nicholls
WA19924 : A Multi-center ,randomized, blinded, parallel-group study of the reduction of signs and symptoms during monotherapy treatment with
tocilizumab 8mg/kg intravenously versus adalimumab 40mg subcutaneously in patients with rheumatoid arthritis.
Clinical Trial
Peter Nash
David Nicholls
CL3- 018 : A prospective multicentre, international, double-blind, placebo-controlled study for the efficacy and safety of two doses of strontium
ranelate (1g and 2g per day) versus placebo administered orally for 2 years in the treatment of knee osteoarthritis.
Clinical Trial
Peter Nash
David Nicholls
RA0055 : A MULTI-CENTER, RANDOMIZED, DOUBLE-BLIND,PLACEBO-CONTROLLED STUDY TO EVALUATE THE EFFICACY AND
SAFETY OF CERTOLIZUMAB PEGOL IN COMBINATION WITH METHOTREXATE FOR INDUCING AND SUSTAINING CLINICAL RESPONSE
IN THE TREATMENT OF DMARD-NAÏVE ADULTS WITH EARLY ACTIVE RHEUMATOID ARTHRITIS
Clinical Trial
Peter Nash
David Nicholls
RA0077: A MULTICENTER, SINGLE-BLIND, RANDOMIZED PARALLEL-GROUP STUDY TO ASSESS THE SHORT- AND LONG-TERM
EFFICACY OF CERTOLIZUMAB PEGOL PLUS METHOTREXATE COMPARED WITH ADALIMUMAB PLUS METHOTREXATE IN SUBJECTS
WITH MODERATE TO SEVERE RHEUMATOID ARTHRITIS RESPONDING INADEQUATELY TO METHOTREXATE
Clinical Trial
Peter Nash
David Nicholls
EMBODY 1 SL0009 - A PHASE 3, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED,MULTICENTER STUDY OF THE EFFICACY
AND SAFETY OF FOUR 12-WEEK TREATMENT CYCLES (48 WEEKS TOTAL) OF EPRATUZUMAB IN SYSTEMIC LUPUS
ERYTHEMATOSUS SUBJECTS WITH MODERATE TO SEVERE DISEASE.
Clinical Trial
Peter Nash
David Nicholls
- 44 -
Trial Name:
Study Type:
Local Investigator:
Local Co-Investigators:
Trial Name:
Study Type:
Local Investigator:
Local Co-Investigators:
Trial Name:
Study Type:
Local Investigator:
Local Co-Investigators:
Trial Name:
Study Type:
Local Investigator:
Local Co-Investigators:
(EMBODY 4)PROTOCOL SL0012A Phase 3, Multicenter, Open-Label, Extension Study to Assess the Safety and Tolerablilty of Epratuzumab
Treatment in Systemic Lupus Erythematosus Subjects
Clinical Trial
Peter Nash
David Nicholls
Protocol WA16855 : AN OPEN LABEL STUDY OF THE EFFICACY AND SAFETY OF RE-TREATMENTS WITH RITUXIMAB
(MABTHERA/RITUXAN) IN PATIENTS WITH ACTIVE RHEUMATOID ARTHRITIS.
Clinical Trial
Peter Nash
David Nicholls
FX006 - ;A Double-Blind, Randomized, Parallel Group, Dose-Ranging Study Comparing FX006 to Commercially Available Triamcinolone
Acetonide Injectable Suspension in Patients with Osteoarthritis of the Knee
Clinical Trial
Peter Nash
David Nicholls
CL3-12911-040: Knee joint replacement over 5 years in patients with knee osteoarthritis. A long term follow up study in patients of the CL3-12911
018 study
Clinical Trial
Peter Nash
David Nicholls
Awards and Prizes
Dr
Name of
Recipient
Impact
Name of Award
Awarding
entity/organisation
Area or Project
Nicholas
Gray
National
Rural Science Award
Australia and New
Zealand Society of
Nephrology
Peritoneal dialysis in rural Australia
- 45 -
Community and Professional Activities
Title
Name of Staff Member
National/
International
Name of Society
Position Held
Dr
Dr
Nicholas Gray
Nicholas Gray
State
National
Statewide Renal Clinical Network
Australia and New Zealand Society of Nephrology
Dr
Nicholas Gray
National
Royal Australasian College of Physicians
Dr
Nicholas Gray
National
Dr
Dr
Dr
Dr
Rohan Grimley
Rohan Grimley
Peter Larsen
Kelvin Larwood
State
National
State
National
A/Prof
A/Prof
Peter Nash
Peter Nash
International
International
A/Prof
Peter Nash
National
A/Prof
Peter Nash
National
A/Prof
Peter Nash
National
A/Prof
Edward Weaver
National
Australia and New Zealand Dialysis and Transplant
Registry
Statewide Stroke Clinical Network
Australian Stroke Units Network National Committee
Statewide Cardiac Clinical Network
Royal Australian and New Zealand College of
Obstetricians and Gynaecologists
Group for Research Psoriasis and Psoriatic Arthritis
EPOSS (Outcome measures in Pulmonary
Hypertension Systemic Sclerosis)
Australian Rheumatology
Association
Scientific Advisory Committee Australian
Rheumatology Association
Therapeutics Committee Australia and New Zealand
Bone and Mineral Society
Royal Australian & New Zealand College of
Obstetricians and Gynaecologists
Co-Chair
Member, Scientific Program
and Education Committee
Member, Specialist Advisory
Committee in Nephrology
Member, steering committee
- 46 -
Clinical Chair
State Representative
Member
Member
Steering Committee Member
Steering Committee Member
Professional Affairs Committee
Member
Member
Member
Councillor
Major Partners and Linkages
Project:
Principal Investigator:
Partners:
Differential expression of microRNA in psoriasis and psoriatic arthritis
A/Prof Peter Nash
Kuballa A., University of the Sunshine Coast
Project:
Principal Investigator:
Partners:
Efficacy of IL6 inhibition with Tocilizumab in Asthma
A/Prof Peter Nash
Ferreira, M., Queensland Institute of Medical Research
Project:
Principal Investigator:
Partners:
Human and microbial gene expression in early Crohn’s disease: clues to aetiology and pathogenesis
Prof Dario Sorrentino
University of Woollongong
CSIRO Sydney
University of the Sunshine Coast
- 47 -
Contact Details
Associate Professor Steven Coverdale
Acting Director, Regional Clinical Practice Research Centre
University of Queensland, Sunshine Coast Clinical School
Nambour General Hospital
GPO Box 547
NAMBOUR QLD 4560
Phone: 07 5470 5644
Fax: 07 5470 5720
Email: s.coverdale@uq.edu.au
- 48 -

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