Tuesday - Experimental Biology

Transcription

TUESDAY, APRIL 29
Anatomy
913. ANATOMY
914. ANATOMY: TENDONS AND LIGAMENTS
Poster
Poster
Tue. 7:30 am—San Diego Convention Center, Exhibit Halls A-D
Presentation time: 12:15 pm–1:45 pm
B1
913.1
The anthropometric parameters of organic
evolution at children of junior school age in Astana F.
Suleimenova, A. Aubakirov, Y. Maul, T. Adaibayev and K.
Dosmambetova. Astana Med. Univ., Kazakhstan.
B2
913.2
Preservation of the brain in cadavers embalmed
according to the Thiel protocol L. Filgueira, F. Jungo, M.
Gagliano and P. Yotovski. Univ. of Fribourg, Switzerland.
B3
913.3
Rectus capitis posterior minor and its
relationship to the spinal dura mater: a histological investigation
G. Venne, C.W. Reifel, S.C. Pang and R.E. Ellis. Queen’s
Univ., Canada.
B4
913.4
A deep fascia exists in the midface: the missing
plane coming from the temporal region C. Andretto Amodeo,
A. Innocenti, A. Casasco, D. Barker and G.S. Keller. Cà
Granda Hosp., Milan, Univ. of Pavia and UCLA.
B5
913.5
Thyroid gland’s topography: preliminary results
A.J. Docko, T.M. Yendo, F.C. Hojaij, F.E. Akamatsu and A.L.
Jacomo. Univ. of São Paulo.
B6
913.6
Unraveling the anatomy of the cardiac skeleton
of the heart M. du Plessis, C. Blaak, R.S. Tubbs and M.
Loukas. St. George’s Univ., Grenada.
B7
913.7
Internal anatomy of the infra-renal inferior vena
cava K.C. Bubb, M. du Plessis, M. Loukas and R.S. Tubbs.
St. George’s Univ., Grenada.
B8
913.8
Surgical anatomy of the carotid-recurrent
recess F. Hojaij, F. Akamatsu, A. Itezerote, J. Ribeiro, M.
Andrade and A. Jacomo. Univ. of São Paulo.
B9
913.9
Study of stress induced failure of the bloodgas barrier and the epithelial-epithelial cells connections of
the lung of the domestic fowl, Gallus gallus variant domesticus
after vascular perfusion J.N. Maina and S.A. Jimoh. Univ. of
Johannesburg and Univ. of the Witwatersrand.
B10
913.10 Investigation on the metastatic changes to
the liver as a consequence of metastatic breast cancer: one
cadaver’s story C. Gallegos and G.L. Nusse. San Francisco
State Univ.
B11
913.11 Functional studies on the PKA regulatory
subunit mutant R74C found in Carney complex H. Love and
O. Ogut. Linfield Col., OR and Mayo Grad. Sch.
B12
913.12 Tyre for congenital hip dislocation R.
Karabekova, V. Lozovoy, E. Lozovaya and M. Hamitov.
Astana Med. Univ., Kazakhstan.
B13
913.13 Assessing the accuracy of femoral tunnel
placement in anatomic ACL reconstruction M. Ducsharm, D.
Banaszek, D. Hesse, M. Kunz, C. Reifel and D. Bardana.
Queen’s Univ., Canada.
B14
914.1
Histological characterization of soft-embalmed
porcine tendon and muscle A.J. Martyniuk, R. Easteal and R.
Ellis. Queen’s Univ., Canada.
B15
914.2
Anatomy of the fetlock in goats and sheep:
comparison of sonography and macroscopic anatomy A.
Hirtler and J. Kofler. Univ. of Vet. Med., Vienna.
B16
914.3
Interconnections between the cruciate
ligaments and the menisci in the knee K. Bashir, P. Weninger
and L. Hirtler. Med. Univ. Vienna and Speising Orthoped.
Hosp., Vienna.
B17
914.4
Radiofrequency promotes more collagen
synthesis than low level laser in experimental tendineous
lesion F.E. Akamatsu, W. Teodoro, S. Saleh, F. Hojaij, G.
Camillo, C. Martinez, M. Andrade and A. Jacomo. Univ. of
São Paulo and São Francisco Univ., Brazil.
B18
914.5
COLIIA1 overexpression with low level laser
therapy after experimental injury A. Jacomo, W. Teodoro, S.
Saleh, C. Martinez, M. Ribeiro, F. Hojaij, M. Andrade and
F.E. Akamatsu. Univ. of São Paulo and São Francisco Univ.,
Brazil.
B19
914.6
Structural characterization of the anterolateral
capsule of the knee — a gross anatomic, histological, and
magnetic resonance imaging study of the anterolateral
ligament S. Caterine, R. Litchfield, M. Johnson, M. Sandig
and A. Getgood. Western Univ., Fowler Kennedy Sport Med.
Clin. and Western Univ., London, Canada.
B20
914.7
Feasability of osseous landmarks for
reconstruction of the anterior cruciate ligament — comparison
experts and beginners L. Hirtler, D. Rieschl, A. Lübbers and
P. Weninger. Med. Univ. Vienna and Orthoped. Hosp. Vienna
Speising.
B21
914.8
Tear analysis of the anterior cruciate ligament
using a novel staining method M. Gillespie, A. Jorgensen, D.
Wilkes and J. Wisco. Brigham Young Univ.
B22
914.9
The histological structure of the medial
patellofemoral ligament: implications in knee stability and pain
generation A.B. Veteto, K. Marberry and P. Kondrashov. A.T.
Still Univ.
B23
914.10 Experimental model of Achilles tendon injury in
rats F.E. Akamatsu, W. Teodoro, S. Saleh, A. Silva, F. Hojaij,
C. Martinez, M. Andrade and A. Jacomo. Univ. of São Paulo
and São Francisco Univ., Brazil.
B24
914.11 Geometric morphometrics of the distal
radioulnar joint of felids and canids B. Carlon. Northern Illinois
Univ.
303
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ANATOMYTUESDAY
915. ANATOMY: FORM AND VARIATION
Poster
Poster
B25
915.1
The prevalence of cryptorchidism among male
infants of Nigerian population: a case study of Imo State C.J.
Ihentuge and C.O. Ugochukwu. Imo State Univ., Nigeria.
B26
915.2
Duplicate caudate lobe of liver with oblique
fissure and hypoplastic left lobe of liver R. Singh. AIIMS
Rishikesh, India.
B27
915.3
Anatomic study of the volar surface of the
distal radius M.D. Barros, A.C.D. Costa, M.F.F.F.H.D. Barros
and I.D. Chakkour. Santa Casa Sch. of Med. Sci. and Santa
Casa Sch. Hosp., IMSCSP, São Paulo.
B28
915.4
Variations in the incidence of sacral hiatus in
macerated human sacred: gender differences A.F. Garcia, J.P.
da Silva, V.S. Fazan and J.A. Thomazini. Univ. of São Paulo,
Ribeirão Preto.
B29
915.5
Morphometrics of the human lumbar spine M.
Jelaca-Tavakoli. Southwestern Col., CA.
B30
915.6
Unilateral absence of the musculocutaneous
nerve with subsequent median nerve innervation: a case report
with embryological and clinical significance D.G. Shiwlochan,
S.N. Gopal, A.G. Shiwlochan, B.V. Murlimanju and S.
Viswanath. American Univ. of Antigua Col. of Med., NY.
B31
915.7
Anatomic localization of nerve entry points in
the gluteus maximus muscle: preliminary results T.M. Yendo,
A.M. Itezerote, A.L. Jacomo and F.E. Akamatsu. Univ. of São
Paulo Fac. of Med.
B32
915.8
Bilateral variations of the brachial plexus
involving the lateral cord and median nerve: an anatomical case
study with clinical implications J.J. Butz, D.G. Shiwlochan,
K. Brown, B. Murlimanju and A. Prasad. American Univ. of
Antigua, NY.
B33
915.9
A unique case of bilateral sciatic nerve variation
within the gluteal compartment J.J. Butz and D.V. Raman.
American Univ. of Antigua, NY.
B34
915.10 Unilateral variant motor innervations of flexor
compartment of arm C. Purushothama. Med. Univ. of the
Americas, Saint Kitts and Nevis.
B35
915.11 Variant leg muscles involved with tarsal
tunnel syndrome: cadaveric case studies H.W. Lambert, P.M.
Kennedy, K.C. Whipp, Z.V. Anderson, M.J. Clarkson and
J.N. Fox. West Virginia Univ. Sch. of Med.
B36
915.12 First report of a “latissimo-cleidocostal” muscle
variant on the anterolateral thoracic wall J.M. Miller, R.B.
Trelease and Z. Sun. UCLA.
B37
915.13 Accurate morphology of the semispinalis
capitis muscle M. Bee, N. Mehrabi, E. Albrecht, S. Michalak,
G. Grabowski and J. Montante. Univ. of Detroit Mercy.
B38
915.14 Variations in the anatomical structures
surrounding the transverse process of the atlas (C1) in 15
cadavers P-W. Kim and F. Ledwitz-Rigby. Life Univ.
B39
915.15 Morphometric analysis of the bony structures
associated with the transcondylar approach M. LoPresti, L.
Auquilla, R. Akintayo, N. Nwogu and C. Erkuran Yilmaz.
Sophie Davis CUNY.
304
916. ANATOMY: GASTROINTESTINAL
B40
916.1
Ontogenic analysis of the PACAP receptor,
PAC1R, in mouse major salivary glands N. Nonaka and M.
Nakamura. Showa Univ.
B41
916.2
Factor
VIII-related
antigen
detects
transformation of liver sinusoidal to vascular endothelium in
hepatic fibrosis of elderly cadavers K.M. Mak and P. Sehgal.
Icahn Sch. of Med. at Mount Sinai.
B42
916.3
Case report of a giant hepatic cyst observed
during routine dissection in gross anatomy lab M. Siu, H. Khey
Beldman, H. Chang, M. Garach, N. Moldovan, B.X. Yu and
A. Farias. Western Univ. and Schulich Sch. of Med. & Dent.,
Windsor Prog., Canada.
B43
916.4
Human intestinal tract length and relationship
with body height E. Minko, A.S. Pagano, N. Caceres, T. Adar
and S. Márquez. SUNY Downstate Med. Ctr. and Icahn Sch.
of Med. at Mount Sinai.
B44
916.5
Lymphoid formation of mucous membrane
of a human rectum Y.Y. Maul, A.B. Aubakirov and F.M.
Suleimenova. Astana Med. Univ., Kazakhstan.
B45
916.6
Gluten-like cellular response of maize
prolamins in intestinal biopsies and Caco-2 cells J.P. OrtizSánchez, A.M. Calderón de la Barca, V. Mata-Haro, J.
Hernández-López and F. Cabrera-Chávez. Ctr. for Food Res.
and Develop. AC, Hermosillo, Mexico and Autonomous Univ. of
Sinaloa.
917. ANATOMY: ANATOMY ONTOLOGIES
Poster
B46
917.1
CAVE — a proposed ontogeny ontology R.J.
Cork. LSU Hlth. Sci. Ctr. , New Orleans.
918. FORM, FUNCTION AND EVOLUTION:
COMPARATIVE AND FUNCTIONAL STUDIES OF
THE HEAD
Poster
Evolution/Anthropology
B47
918.1
Y-chromosome amelogenin isoform peptides
found in mature dental enamel R.F. Gerlach, G.F. Molina,
J.P.M. Issa, M. Sosovicka, S.R.P. Line and A.R. Vieira. Univ.
of São Paulo, Ribeirão Preto, Univ. of Pittsburgh and State
Univ. of Campinas, Ribeirão Preto.
B48
918.2
Mature dental enamel: a diverse repository
of past and present information R.F. Gerlach and S.R.P.
Line. Univ. of São Paulo, Ribeirão Preto and State Univ. of
Campinas, Piracicaba, Brazil.
TUESDAYANATOMY
B49
918.3
Comparative analysis on the frequencies
and mortality rates of muscle, fascia, and sinus locations on
trephined crania in ancient Peru A.S. Bilal and M. JelacaTavakoli. San Diego State Univ. and Southwestern Col., CA.
B50
918.4
Phenotypic similarities and dissimilarities in a
Paleoamerican sample: what are the implications in modeling
the first migrations into the New World K. Alsup. Univ. of
Michigan.
B51
918.6
External ear anthropometry: the search for
sexual dimorphism and correlations among Nigerians M.G.
Taura. Bayero Univ. Kano, Nigeria.
B52
918.7
The ontogeny of sexual dimorphism in the skull
of the springbok antelope (Antidorcas marsupialis) K. Brakora.
UCSF.
B53
918.8
An animated 3D model of the synchronous
movements of the suprasyringeal structures and organs
in the neck of a vocalizing songbird, the Northern Cardinal
(Cardinalis cardinalis) C.E. Blevins, J. Ge, R.A. Suthers and
D.G. Homberger. LSU and Indiana Univ.
B54
918.9
Anatomical diversity of the avian feeding
system: preliminary analysis of the hyolingual apparatus E.
Heiner and L. Witmer. Ohio Univ.
B55
918.10 The cervical cutaneous and subcutaneous
structures in songbirds and their possible roles in vocalization
A. Cozic, R.A. Suthers and D.G. Homberger. LSU and
Indiana Univ.
B56
918.11 The cranial morphology of large captive versus
wild felids A. Hartstone-Rose, H. Selvey, B. Boyde and J.
Villari. Univ. of South Carolina Sch. of Med., Univ. of South
Carolina, George Mason Univ. and Smithsonian Instn.
B57
918.12 Modeling the epigenetic influence of climate on
upper respiratory tract proportions with two groups of Macaca
mulatta A.S. Pagano and J.T. Laitman. Icahn Sch. of Med. at
Mount Sinai.
B58
918.13 Frequency and evolutionary importance of
human palatal pneumatization D. Swerdloff, A.S. Pagano,
B.N. Delman, T. Adar, W. Lawson and S. Marquez. SUNY
Downstate Med. Ctr. and Icahn Sch. of Med. at Mount Sinai.
B59
918.14 Energetic costs of feeding behaviors in the
aye-aye, Daubentonia madagascariensis M. Toler, J. Hanna,
M.C. O’Neill and C.E. Wall. Duke Univ., West Virginia Col. of
Osteo. Med. and Stony Brook Univ. Sch. of Med.
B60
918.15 Bite force patterns along the tooth row in
anthropoid primates L. Lucas. Univ. of Arizona Col. of Med.Phoenix.
B61
918.16 Evolution of primate ganglion cells sensitive
to short wavelengths D.W. Marshak and S.L. Mills. Univ. of
Texas Med. Sch., Houston.
B62
918.17 Morphometry and fabric orientation of
trabecular bone in human craniofacial regions L.C. Pryor
Smith, P.C. Dechow and T.E. Yardley. Texas A&M Univ. Hlth.
Sci. Ctr., Dallas.
B63
918.18 A rhesus model for the study of the sutures
at pterion Q. Wang, T.B. Kensler, E. Maldonado and M.Q.
Zhao. Mercer Univ. Sch. of Med., Caribbean Primate Res. Ctr.,
San Juan, Caribbean Primate Res. Ctr., Sabana Seca, PR and
Mercer Univ.
B64
918.19 Did speech slow down the human face? Human
facial muscles have a high proportion of slow myosin fibers
compared to other primates A.M. Burrows, E.L. Durham, T.D.
Smith and L.A. Parr. Duquesne Univ., Slippery Rock Univ., PA
and Emory Univ.
B65
918.20 The opening and closing mechanism of the
spiracle in the spiny dogfish shark, Squalus acanthias K.L.
Paulk, S.C. McFerren and D.G. Homberger. LSU.
B66
918.21 Stretchy nerves withstand deformation
associated with lunge feeding in rorqual whales A.W. Vogl,
M. Lillie, M. Piscitelli and R.E. Shadwick. Univ. of British
Columbia.
B67
918.22 Interspecific comparison of ontegenetic change
in temporal bone pneumatization C. Hill. Univ. of Arizona Col.
of Med.-Phoenix.
B68
918.23 Developmental changes in cross-sectional
geometry of the mandibular corpus C.L. Fojas. Univ. of
Tennessee, Knoxville.
B69
918.24 Withdrawn.
B70
918.25 Concurrent growth of the skull and aerodigestive
tract of human infants: setting a protocol for study D.F. Curcio,
B.M. Micham, J. Reidenberg and J.T. Laitman. Santa Casa
Sch. of Med. Sci., Brazil and Icahn Sch. of Med. at Mount Sinai.
B71
918.26 Human embryonic larynx morphogenesis:
three-dimensional and multiplanar study M. Labrouse, R.
Tonnelet, Y. Renard, E. Micard, F. Duparc, V. Delmas and M.
Braun. Fac. of Med. and Univ. Hosp., Univ. of Reims, INSERM
U947, Univ. of Lorraine, CHU of Nancy Brabois, Fac. of Med.
and Univ. Hosp., Univ. of Rouen, Fac. of Med., Univ. Paris
Descartes and Fac. of Med. and Univ. Hosp., Nancy, Univ. de
Lorraine.
B72
918.27 Specialize or disappear: anisomerism, empirical
evidence of the differentiation or loss of polyisomere structures
during gnathostome evolution based on a comparative study of
head and appendicular muscles J.M. Ziermann and R. Diogo.
Howard Univ. Col. of Med.
B73
918.28 Quantifying
adaptive
evolution:
threedimensional phenotypes provide new insight into mechanisms
of rapid evolutionary change in threespine stickleback H.A.
Jamniczky. Univ. of Calgary, Canada.
919. FORM, FUNCTION AND EVOLUTION:
COMPARATIVE AND FUNCTIONAL STUDIES OF
THE POSTCRANIA
Poster
Evolution/Anthropology
B74
919.1
The body mass estimation from human talus:
inductive approach and 3D morphometric study G-U. Jung,
U-Y. Lee, D-H. Kim, D-S. Kwak, Y-W. Ahn and Y-S. Kim. Sch.
of Med., Ewha Womans Univ., Catholic Univ. of Korea and Sch.
of Med., Pusan Natl. Univ., South Korea.
B75
919.2
Relative
long
bone
proportions
and
developmental stress in a modern Thai population K.R.
Rectenwald. Univ. of Tennessee, Knoxville.
B76
919.3
Deconstructing the dogma of fore and hindlimb
serial homology: evidence from regenerative, developmental,
comparative, paleontological and evolutionary studies R.
Diogo, J.M. Ziermann and P. Johnston. Howard Univ. Col. of
Med. and Univ. of Auckland.
B77
919.4
Is evolutionary biology becoming too politically
correct? A reflection on the scala naturae, phylogenetically
basal clades, anatomically plesiomorphic taxa, and “lower”
animals R. Diogo, J.M. Ziermann and M. Linde-Medina.
Howard Univ. Col. of Med. and Univ. of Manchester.
305
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ANATOMYTUESDAY
B78
919.5
First detailed comparative, developmental
and pathological analysis of the relationship between limb soft
and hard tissues: muscle configuration is mainly related to
the topological position, and not the anlage and/or homeotic
identity, of digits R. Diogo, S.M. Walsh, C. Smith and J.M.
Ziermann. Howard Univ. Col. of Med. and Johns Hopkins Univ.
B79
919.6
Evolutionary convergence of digit loss by
overlapping mechanisms in multiple species of mammals K.
Cooper, K. Sears, A. Uygur, J. Maier and C. Tabin. UCSD,
Univ. of Illinois at Urbana-Champaign and Harvard Med. Sch.
B80
919.7
The devil is in the details: identification of
postcranial elements of Canis dirus and Canis lupus from
Rancho La Brea using discriminant function and morphometric
analyses L. Koper. Northern Illinois Univ.
B81
919.8
Creating testing regimes for terrestrial origins
of the avian flight stroke T.A. Dececchi, M.B. Habib and J.B.
Hall. Univ. of South Dakota and Univ. of Southern California.
B82
919.9
Investigating the function of the caudofemoralis
longus muscle and musculoskeletal plasticity in American
alligators (Alligator mississippiensis) J.R. Joneson, A.C.
Medina, T. Owerkowicz and R.M. Elsey. California State
Univ., San Bernardino and Rockefeller Wildlife Refuge, Grand
Chenier, LA.
B83
919.10 Can morphological variables be used to
predict hip joint function? An examination of the anthropoid
proximal femur and range of abduction A.S. Hammond, J.M.
Plavcan and C.V. Ward. Univ. of Missouri-Columbia and Univ.
of Arkansas.
B84
919.11 Hip center edge angle and alpha angle
correlate with gait variables in femoroacetabular impingement
morphology G.J. Farkas, M. Haro, S. Lee, A.A. Espinoza
Orias and S.J. Nho. Rush Univ. Med. Ctr.
B85
919.12 The effect of AFO stiffness on the knee joint
during the heel strike phase of gait in stroke patients M.L.
Singer, T. Kobayashi, L. Lincoln, M.S. Orendurff and K.B.
Foreman. Univ. of Utah and Orthocare Innovations, Mountlake
Terr., WA.
B86
919.13 Application of ischium-pubis index for sex
determination using ihree-dimensional models D-H. Kim, G-U.
Jung, Y-S. Kim and U-Y. Lee. Col. of Med., Catholic Univ. of
Korea and Ewha Womans Univ. Sch. of Med., South Korea.
B87
919.14 Sex dimorphism of the sacroiliac joint and
its relation to joint mobility and function N. Clements, M.
Johnson, M. Mottola and H. Gillis. Western Univ., Canada.
B88
919.15 Effects of the curvature of the lumbar spine on
the posture of male and female horse riders: a biomechanical
analysis M.L. Osborn, J.L. Cornille and E.W. Uhl. Univ. of
Georgia Col. of Vet. Med. and Sci. of Motion, Eatonton, GA.
B89
919.16 Higher lumbar lordosis among women: a study
examining lumbar angle and dorsoventral wedging of vertebral
bodies and discs in standing and supine radiographs J.F.
Bailey, E. Been and P.A. Kramer. Univ. of Washington, Ono
Academic Col., Israel and Tel Aviv Univ.
B90
919.17 Anatomical study of distal ulna and correlation
with the etiology of wrist pain and gender M.D. Barros, A.C.D.
Costa, L.V.D. Vuono and I.D. Chakkour. Santa Casa Sch. of
Med. Sci. and Santa Casa Sch. Hosp. - IMSC, São Paulo.
306
920. BONES, CARTILAGE AND TEETH
Poster
B91
920.1
How do the bone elastic properties vary
through different layers of the skull? U. Zapata and Q. Wang.
Univ. EAFIT, Colombia and Mercer Univ.
B92
920.2
Three-dimensional
analysis
of
basic
multicellular units using micro-computed tomography:
Does morphology indicate behavior? K.D. Harrison, S.A.
Tsukamoto and D.M. Cooper. Univ. of Saskatchewan and
Brandon Univ., Canada.
B93
920.3
Avascularity in the cortical bone of small bats
as revealed by micro computed tomography I.V. Pratt, E.G.
Walker and D.M.L. Cooper. Univ. of Saskatchewan.
B94
920.4
Investigation of the role of calcaneal dimensions
in pes cavus and pes planus K. Van Osch, M. Johnson,
M. Balsdon, C. Dombroski and T. Jenkyn. Western Univ.,
Canada and SoleScience, Fowler Kennedy, London, ON.
921. BONES, CARTILAGE AND TEETH:
DEVELOPMENT
Poster
B95
921.1
Role
of
hepatic
cytochrome
P450
oxidoreductase in bone development D. Kellogg, K. Tang,
L.J. Roman, R.J. Fajardo, B.S.S. Masters and S.P. Panda.
Univ. of Texas Hlth. Sci. Ctr. at San Antonio.
B96
921.2
Jagged1 is essential and sufficient for
osteoblast development during maxillary ossification C.R. Hill,
M. Yuasa, J. Schoenecker and S. Goudy. Vanderbilt Univ.
B97
921.3
Effects of the propylthiouracil on tooth
development in newts Y. Miwa, M. Sunohara, K. Shimada
and I. Sato. Nippon Dent. Univ.
B98
921.4
Ephrin reverse signaling induces mouse
palatal fusion without TGFβ3 signaling M.J. Serrano, P.A.
Hills, I. Pourmand, A. Varghese, K.K.H. Svoboda and M.D.
Benson. Baylor Col. of Dent.
B99
921.5
miRNAs as the molecular clock regulating
mandibular osteoinduction R.R. Roberts and A.E. Merrill.
Univ. of Southern California.
B100 921.6
A noncanonical nuclear role for fibroblast
growth factor signaling in skeletal development J.E. Salva,
C.L. Neben and A.E. Merrill. Univ. of Southern California.
B101 921.7
The effects of eggshell removal on embryonic
skeletal development in the American alligator (Alligator
mississippiensis) N.A. Membreno, R.M. Elsey and T.
Owerkowicz. California State Univ., San Bernardino and
Rockefeller Wildlife Refuge, Grand Chenier, LA.
B102 921.8
Developmental origins of the stomodeum links
brain and jaw size evolution J.L. Fish and R.A. Schneider.
UCSF.
B103 921.9
Molecular
mechanisms
that
mediate
mechanosensation during secondary chondrogenesis K.
Woronowicz, M. Hague and R. Schneider. UCSF.
B104 921.10 Parallelism between ontogeny and phylogeny —
a case study in amphibians J.M. Ziermann and R. Diogo.
Howard Univ. Col. of Med.
TUESDAYANATOMY
922. BONES, CARTILAGE AND TEETH: DISEASE
AND REPAIR
Poster
B105 922.1
Subnasale to gnathion distance and nasal
index of children with homozygous sickle cell disease in Port
Harcourt, Nigeria A.E. Ligha and H.B. Fawehinmi. Niger
Delta Univ. and Univ. of Port Harcourt, Nigeria.
B106 922.2
Susceptibility of the aging thorax to motor
vehicle crash injuries M.R. Sochor, S. Heltzel and R. Kent.
Univ. of Virginia.
B107 922.3
A one month old infant misdiagnosed with
parietal bone fracture and child abuse J.D. Collins, E.H.
Saxton and A. Carnes. UCLA and UCSF, Fresno.
B108 922.4
Consequence of various wrist angulations
at impact on the severity of Colles’ fractures S. Baral, D.
Chatterjee, N. Caceres, G. Feuer, W. Hayes, C. Jones, S.
Saha and S. Marquez. SUNY Downstate Col. of Med. and
SUNY Downstate.
B109 922.5
A study of the mandibular incisive nerve and
possible causes of altered sensation following maxillofacial
surgery D.D. Ivey, T.D. Wilson, P. Merrifield, M. Shimizu and
K. Galil. Western Univ. and London Hlth. Sci. Ctr., Canada.
B110 922.6
A comprehensive analysis of zygomatic
symmetry and implications for zygomatic bone reconstruction
A. Belcastro, M. Johnson, K. Galil, T. Jenkyn, R. Willing
and A. Yazdani. Western Univ., Canada, Binghamton Univ.,
SUNY and Western Univ., London, ON.
B111 922.7
Consequences of the loss of collagen XXIV in
bone M.K. Gordon, J.Y.L. Jeon, P. Zhou, R.A. Hahn, K.K.H.
Svoboda and F. Ramirez. Rutgers Univ., Piscataway, Baylor
Col. of Dent., Texas A&M Hlth. Sci. Ctr. and Mount Sinai Sch.
of Med.
B112 922.8
The role of TGFβ1 and HTRA1 in the
pathogenesis of TMJ osteoarthritis P. Wong, D. Reece, J.
Hepworth, S. Wilhelm, D. Mecham, D. Kooyman and R.
Seegmiller. Col. of Dent. Med., Roseman Univ. of Hlth. Sci.,
UT and Brigham Young Univ.
B113 922.9
Expression
and
immunohistochemical
localization of the Gβγ-activated and calcineurin-inhibited
adenylyl cyclase isoforms in rat articular chondrocytes I.
Memon, K.M. Khan, S. Siddiqui, S. Perveen and M. Ishaq.
King Saud bin Abdulaziz Univ., Kuwait Univ., Aga Khan Univ.,
Pakistan and United Med. and Dent. Col., Pakistan.
B114 922.10 Extracellular matrix protection factor treatment
in a rat model of osteoarthritis slows the progress of cartilage and
bone destruction associated with the disease S. Chmielewski,
E. Cho, L. Lukashova, S. Friedrich, S. Althauser, A. Selim
and M. D’Angelo. Philadelphia Col. of Osteo. Med. and Hosp.
for Spec. Surg., NY.
B115 922.11 Extracellular matrix protection factor: a novel
class of post-traumatic osteoarthritis therapeutic E. Cho, S.
Chmielewski, J. Nolt, J. Klunk, J. Youngwirth, D. Palumbo,
T. Maugle, L. Lukashova, D. Belogorodsky, T.M. Holmes,
S. Althauser, N. Pinkney, A. Selim and M. D’Angelo.
Philadelphia Col. of Osteo. Med. and Hosp. for Spec. Surg., NY.
B116 922.12 A new class of osteoarthritis therapeutic,
extracellular matrix protection factor, alters cytokine production
in chondrocytes C.K. Docherty, D. Belogorodsky, E. Cho,
S.E. Chmielewski, S. Lopez, T. Holmes and M. D’Angelo.
Philadelphia Col. of Osteo. Med.
B117 922.13 Microscopic analysis of characteristic surface
features of a set of retrieved total hip implants M.A. Burbano,
D. Roy, R. Russell, M. Huo and D.C. Rodrigues. Univ. of
Texas at Dallas and Univ. of Texas Southwestern Med. Ctr.
B118 922.14 Effects of insertion forces on the surface wear
of dental implants A. Adapalli, S. Sridhar, A. Thomas, P.
Valderrama, T.G. Wilson and D.C. Rodrigues. Univ. of Texas
at Dallas and Texas A&M Univ. Baylor Col. of Dent.
B119 922.15 Cissus quadrangularis has anti-oxidant and
anti-inflammatory properties: in vitro and in vivo studies
J.F. Navarro, J.C. Espinosa, K. Das, B. Faraji, W. InnisWhitehouse, S-G. Wei and J. Banu. Univ. of Texas-Pan
American, Texas Tech Hlth. Sci. Ctr. at El Paso and Univ. of
Texas Hlth. Sci. Ctr. at San Anotnio.
B120 922.16 Bone regeneration is not affected by medullary
canal size in four different mouse strains after marrow ablation
M.M. Moran, A.S. Virdi, K. Sena, M.A. McNulty and D.R.
Sumner. Rush Univ. Med. Ctr., Kagoshima Univ., Japan and
LSU.
B121 922.17 Effectiveness of diode laser 904nm in the
regeneration of bone defects in diabetic rats J.P. Silva, V.P.S.
Fazan, L.C. Pardini and J.A. Thomazini. Sch. of Med. of
Ribeirão Preto and Sch. of Dent. of Ribeirão Preto, Brazil.
B122 922.18 Interaction between rhBMP-2 and different
types of bone grafts J.P.M. Issa, F.J. Dias, V.P. Fazan, E.
Ervolino, M.M. Iyomasa, R.F. Gerlach, B.G.S. Kotake and
M.G. Gonzaga. Univ. of São Paulo Fac. of Dent., Ribeirão
Preto, Univ. of São Paulo Inst. of Biomed. Sci., Ribeirão Preto
and São Paulo State Univ. Fac. of Dent., Aracatuba.
B123 922.19 Covalent attachment of antibiotics to bone
allograft N. Swisher, C. Adams, V. Dattilo and R. Saunders.
Philadelphia Col. of Osteo. Med.
B124 922.20 Characterization of calcium phosphate
composite two solution bone cements J. Chari, L. Rodriguez,
S. Aghyarian and D. Rodrigues. Univ. of Texas at Dallas.
923. IMAGING: ANATOMY
Poster
Imaging
B125 923.1
Instrumentation for capture of high-speed
anatomical movement M. Sochor and S. Heltzel. Univ. of
Virginia.
B126 923.2
Creating 3D virtual models from CT and MRI
for anatomy education J. Chen, A.K. Pavlov, A. Smith, A.R.
Sinning, M.L. Conway and D. Cui. Univ. of Mississippi Med.
Ctr.
B127 923.3
A half-sized écorché by Talrich (19th century)
description of an anatomical model in plaster on a posterior
view P.P. Le Floch-Prigent and J-B.A. Gillot. Univ. of
Versailles-SaintQuentin and Sci. Library Alain Brieux, Paris.
B128 923.4
A half-sized écorché by Talrich (19th century),
description of an anatomical model in plaster on an anterior
view P.P. Le Floch-Prigent and J-B.A. Gillot. Univ. of
Versailles-SaintQuentin and Alain Brieux Sci. Library, Paris.
B129 923.5
Localization of the recurrent laryngeal nerve
using ultrasound M. Snosek, G. Margarit, D. Burns, R. Hage,
S. Tubbs and M. Loukas. St. George’s Univ., Granada.
307
T
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ANATOMY/BIOCHEMISTRY TUESDAY
B130 923.6
Fetal developmental anatomy of the human
cardiovascular and central nervous systems using Lugol’s
iodine staining and micro-computed tomography A. Spaw and
L. Witmer. Ohio Univ.
B131 923.7
Embryology of extraocular muscles: a new
vision F.M. Tréchot, R. Tonnelet, E. Micard, M. Labrousse,
K. Angioi and M. Braun. CIC-IT, Nancy, CHU de Nancy and
CHU de Reims.
B132 923.8
Semi-automated method for 3-dimensional
visualization of skeletal muscle extracellular collagen
ultrastructure A.R. Gillies and R.L. Lieber. UCSD.
B133 923.9
3D imaging of the muscle fibers of the
supraspinatus for improved rotator cuff repair A. Jorgensen
and J.J. Wisco. Brigham Young Univ. and Univ. of Utah Sch.
of Med.
B134 923.10 Real-time in vitro monitoring of impedance in
rat bone-like cells (UMR 106-01 BSP) E. Joseph, N. Joshi
and K. Kim. La Sierra Univ.
B135 923.11 Color-coded chemotherapy: S/G2-phasetrapping by methioninase pre-treatment, indicated by FUCCI
imaging, enables highly effective cancer chemotherapy S.
Yano, Y. Tome, M.A. Digman, M. Momiyama, A. Suetsugu,
E. Gratton and R.M. Hoffman. AntiCancer Inc., San Diego
and Univ. of California, Irvine.
Biochemistry and Molecular Biology
924. ARCHITECTURE AND DYNAMICS OF
REPLICATION, REPAIR, AND RECOMBINATION
COMPLEXES
Poster
D1
924.1
Hrq1, a homolog of the human RecQ4 helicase,
acts catalytically and structurally to promote genome integrity
M.L. Bochman, K.E. van Kessel and K. Paeschke. Indiana
Univ. and Univ. of Wurzburg.
D2
924.2
Mechanistic insights into PriA mediated DNA
replication restart T. Thurmes, B. Bhattacharyya, R. Zhou,
M. Leroux, S. Sandler, T. Ha and J. Keck. Univ. of WisconsinMadison, Univ. of Illinois, Urbana, Univ. of Massachusetts
Amherst and Univ. of Wisconsin.
925. POST-TRANSLATIONAL MODIFICATIONS IN
REPLICATION, REPAIR, AND RECOMBINATION
Poster
D3
925.1
Nucleosome acidic patch promotes H2AX and
H2A ubiquitination and DNA damage signaling K. Miller. Univ.
of Texas at Austin.
D4
925.2
Evidence for the hypothesis that two forms of
human DNA polymerase δ participate in DNA replication S.H.S.
Lin, S. Zhang, E.Y. Lee and Z. Zhang. New York Med. Col.
D5
925.3
A new approach to study site-specific protein
sumoylation C.P. Albuquerque, E. Yeung, S.X. Ma, T. Fu and
H. Zhou. Ludwig Inst. for Cancer Res., UCSD and UCSD.
D6
925.4
Analysis of yeast SUMO ligase MMS21dependent genome maintenance pathway J. Liang, N.S. Lee,
C.P. Albuquerque, C.D. Putnam, R.D. Kolodner and H.
Zhou. UCSD Sch. of Med. and UCSD.
D7
925.5
Protein acetylation contributes to higher
genome fidelity during replication and repair L. Balakrishnan
and R.A. Bambara. Univ. of Rochester Sch. of Med. and Dent.
308
926. TELOMERES AND TELOMERASE
Poster
D8
926.1
Biophysical analysis of the human POT1-TPP1
complex reveals functional protein-protein and protein-DNA
interactions involved in telomere maintenance D.J. Taylor, M.
Rajavel, D. Baus, T. Orban and K. Palczewski. Case Western
Reserve Univ.
D9
926.2
The architecture of Tetrahymena telomerase J.
Feigon. UCLA.
D10 926.3
Tpz1 switches telomeres between ON and
OFF states F. Qiao. Univ. of California, Irvine.
927. TRANSLESION AND ERROR-PRONE DNA
POLYMERASES
Poster
D11
927.1
Characterization of putative mutagenesis
cassettes in Sinorhizobium meliloti S.M. Genardi, N.A.
DeLateur, C. Kramer, B. Leifer, T.E. Brewer, K.M. Jones and
P. Beuning. Northeastern Univ. and Florida State Univ.
D12 927.2
The architecture of yeast DNA polymerase
zeta R. Malik, Y.G. Llorente, R. Jain, J.R. Choudhary, R.
Johnson, L. Prakash, S. Prakash, I. Ubarretxena-Belandia
and A.K. Aggarwal. Icahn Sch. of Med. at Mount Sinai and
Univ. of Texas Med. Branch.
D13 927.3
Mechanism of hRev1 polymerase action
on G-quadruplex DNA S. Eddy, M.K. Zafar, A. Ketkar, L.
Maddukuri and R.L. Eoff. Univ. of Arkansas for Med. Sci.
D14 927.4
Novel ubiquitin binding sites of S. cerevisiae
polymerase η identified by a genetically encoded photoactive
probe M. Urban, K. Yang and Z. Zhuang. Univ. of Delaware.
TUESDAYBIOCHEMISTRY
928. DNA
Poster
D15 928.1
A bologist’s resource for plasmids: the DNASU
and Protein Structure Initiative:Biology-Materials repositories
C. Seiler, J.G. Park, M. Fiacco, A. Throop, J. Steel, P. Hunter
and J. LaBaer. Arizona State Univ.
D16 928.2
Biological activity of a set of new copper(II)
complexes:
toward
understanding
structure-reactivity
correlations C.L. Aitken, J. Tanski, K. Fox and L. Tyler. Union
Col., NY and Vassar Col.
D17 928.3
Determining the genetic basis of equine
deafness via candidate gene studies K.A. Innamorati and
K.A. Lipsett. Gettysburg Col.
D18 928.4
Identification of a DNA aptamer for the
detection of sucralose in environmental water samples G.
Robbins-Welty and A.D. Parente. Mercyhurst Univ.
929. DNA STRUCTURE
Poster
D19 929.1
Minor groove geometry determines DNA
exclusion from nucleosomes D. Grilley. Univ. of Wisconsin-La
Crosse.
930. UBIQUITINATION
Poster
D20 930.1
Elucidating the role of de novo mutations of
cullin-3 in hypertension S-R.C. Ibeawuchi, L.N. Agbor, F.W.
Quelle and C.D. Sigmund. Univ. of Iowa.
D21 930.2
Mutation in the PPARG ligand binding domain
impairs PPARG-mediated turnover of the p65 subunit of NFκB M. Mukoda, M. Stump, P. Ketsawatsomkron, F.W. Quelle
and C.D. Sigmund. Univ. of Iowa.
D22 930.3
Dysfunction of polyubiquitin binding by ABIN1
as a basis for lupus nephritis E. Korte, R. G’Sell, R. Sheehan,
D. Caster and D. Powell. Univ. of Louisville.
D23 930.4
Examining the temporal expression and
regulation of type I MAGE proteins in spermatogenesis M.A.
Quintana, K. Fon Tacer, Y-H. Hao and R. Potts. San Diego
State Univ. and Univ. of Texas Southwestern Med. Ctr.
D24 930.5
MAML1 mediates MEF2C degradation
independent of ubiquitination I.A. Zein and B. White. San
Jose State Univ.
D25 930.6
ITCH E3 ubiquitin ligase positively regulates
TGF-β signaling to EMT via Smad7 ubiquitination C-H. Woo
and J.H. Lim. Yeungnam Univ. Col. of Med. and Ewha Womans
Univ. Sch. of Med., South Korea.
931. PROKARYOTIC AND ARCHAEAL UBIQUITINLIKE MODIFIERS
Poster
D26 931.1
Ubiquitin-fold protein and JAMM/MPN+
metalloprotease constitute a regulating system for enzyme
inhibition and activation S. Cao and N. Hepowit. Univ. of
Florida.
D27 931.2
Conjugation of ubiquitin and ThiS in an
archaeal system N. Hepowit, A. Berganini and J. MaupinFurlow. Univ. of Florida.
932. PROTEASE ADAPTORS
Poster
D28 932.1
Adaptor-guided proteolysis initiates on the
ribosome N. Puri and W. Karzai. Stony Brook Univ.
933. PROTEASE: STRUCTURE AND REGULATION
Poster
D29 933.1
Subcellular distribution of carboxypeptidase O
affected by nutrient availability P.J. Lyons and D. Dockery.
Andrews Univ., MI.
D30 933.2
Determining the role(s) of prime-side residues
in macromolecular inhibition of trypsin-fold serine proteases
C. St Germain, A.R. Batt and T. Baird. San Francisco State
Univ.
D31 933.3
Crystal
structure
of
Homo
sapiens
neuroblastoma, suppression of tumorigenicity 1 from
DAN (differential screening-selected gene aberrative in
neuroblastoma) gene G. Wang. Southern Illinois Univ.
Carbondale.
D32 933.4
Characterization of StiP, a starvation-induced
cysteine protease from Acinetobacter baylyi M.A. Daugherty,
K.M. Lang, C.P. Lostroh, C. Memmel, S. Bernazzani, B.
Reichert, A. Dornbusch, J. Arguella and S.E. Stanley.
Colorado Col.
934. PROTEASES IN DISEASE
Poster
D33 934.1
Cranberry (Vaccinium macrocarpon) extract
inhibits matrix metalloproteinase expression in aortic smooth
muscle cells by affecting key cell signaling pathways R.
Hurta, A. Thomas, J. Kim, K. Patel and C. Neto. Univ. of
Prince Edward Island, Canada and Univ. of MassachusettsDartmouth.
309
T
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BIOCHEMISTRYTUESDAY
D34 934.2
Screening nicastrin antibodies for specificity
for immunofluorescence D. Deshaies, G. Yu and D.R. Dries.
Juniata Col., PA and Univ. of Texas Southwestern Med. Ctr.
D35 934.3
The role of the PAR2-beta-arrestin signaling
axis in Alternaria and cockroach-induced allergic asthma
M.C. Yee, H. Nichols, K. Pal, S. Sy and K. Defea. Univ. of
California, Riverside.
D36 934.4
V-ATPase-mediated secretion and activation
of cathepsins in breast cancer cells: investigating the role
of vacuolar H+-ATPases subunit A isoforms in breast cancer
metastasis A.M. Hinton. Denison Univ.
D37 934.5
Transcriptional changes in gamma-secretase
conditional knockout mice J. Arbella, G. Yu and D.R. Dries.
Juniata Col., PA and Univ. of Texas Southwestern Med. Ctr.
D38 934.6
Identifying transcriptional changes in an
oligodendrocyte-specific conditional knockout mouse T.M.
Stefanik, G. Yu and D.R. Dries. Juniata Col., PA and Univ. of
Texas Southwestern Med. Ctr.
D39 934.7
Is Arabidopsis thaliana gamma-secretase a
functional protease? J.H. Lee and D. Dries. Juniata Col., PA.
D40 934.8
V-ATPase-mediated activation of cathepsins
in breast cancer cells: investigating the role of vacuolar H+ATPases in breast cancer metastasis A. Uhlman and A.M.
Hinton. Denison Univ.
935. PROTEASOME INHIBITION
Poster
Poster
D47 937.1
A second degradation signal within the shortlived transcription factor MATalpha2 C.M. Hickey and M.
Hochstrasser. Yale Univ.
D48 937.2
Proteasomal inhibition effects Notch signaling
E.M. Chambers, A. Hsu and B. White. San Jose State Univ.
938. UBIQUITIN-LIGASES: STRUCTURE AND
FUNCTION
Poster
D49 938.1
Structures, dynamics, and interactions with
UBC9 of the RING and B1-box domains of promyelocytic
leukemia protein T-h. Huang, S-Y. Huang and M.T. Naik. Inst.
of Biomed. Sci., Acad. Sinica, Taipei.
939. STRUCTURAL AND MECHANISTIC INSIGHTS
INTO TRANSCRIPTION AND RNA PROCESSING
Poster
D41 935.1
Proteasome inhibition increases expression of
angiogenic chemokines in ovarian cancer cells through IKKβ,
S536P-p65 and EGR-1 dependent pathways B. Singha, H.R.
Gatla, T-P. Chang, S. Manna, S. Sanacora and I. Vancurova.
St. John’s Univ.
D42 935.2
Enhancing key radiation induced phenotypic
changes by inhibition of the 26S proteasome in order to
better stimulate immune responses E. Cacan, A. Kumari, C.
Garnett-Benson and S.F. Greer. Georgia State Univ.
D43 935.3
Resveratrol, a novel natural proteasome
inhibitor N. Qureshi, J.C. Reis and A.A. Qureshi. Univ. of
Missouri Med. Sch., Kansas City.
936. PROTEASOMES: STRUCTURE AND
REGULATION
Poster
D44 936.1
Reconstitution of the 26S proteasome reveals
functional asymmetries in its AAA+ unfoldase R. Beckwith, E.
Estrin, E. Worden and A. Martin. Univ. of California, Berkeley.
D45 936.2
Allosteric regulation and substrate specificity
of the proteasome deubiquitinase Rpn11 E.J. Worden and A.
Martin. Univ. of California, Berkeley.
D46 936.3
Substrate recognition and processing by the
eukaryotic 26S proteasome C. Bashore and A. Martin. Univ.
of California, Berkeley.
310
937. UBIQUITINATION AND CHROMATIN
D50 939.1
Structural basis of Rifampin resistance in
bacterial RNA polymerase K. Murakami. Penn State.
D51 939.2
Multiple mechanisms for transcription fidelity
maintenance in vivo I. Huang, M.L. Kireeva, J.D. Irvin, D.R.
Gotte, B.K. Schafer, J.N. Strathern and M. Kashlev. NCI at
Frederick.
D52 939.3
Probing the architecture of the Mediator
complex E. Sierecki, M. Polinkovsky, N. Giles, M. Moustaqil,
K. Alexandrov and Y. Gambin. Univ. of Queensland, Australia.
D53 939.4
The hunt for a PAX3-FOXO1 motif K.E.
Johanson, C.L. Collins, D. Stewart and T. Cherlin. Xavier
Univ. of Louisiana.
D54 939.5
Structural and chemical perspectives of RNA
polymerase II transcriptional fidelity D. Wang. UCSD.
D55 939.6
Identification of critical residues in spliceosomal
protein Dib1 A.L. Lucas, S. Whitten and C. Maeder. Texas
State Univ.
D56 939.7
Double
gene
knockdown
leads
to
X-chromosome reactivation S.K. Thomas, S.P. Sripathy, V.
Leko, E. Foss, U. Lao and A. Bedalov. Providence Col. and
Fred Hutchinson Cancer Res. Ctr.
TUESDAYBIOCHEMISTRY
940. COORDINATION OF TRANSCRIPTION AND RNA
PROCESSING
943. TRANSCRIPTIONAL ASSEMBLIES AND
MECHANISMS
Poster
Poster
D57 940.1
SAGA-mediated acetylation interacts with
Prp5 ATPase activity in pre-mRNA splicing E.C. Merkhofer
and T. Johnson. UCLA and UCSD.
D58 940.2
A novel chemical-genomic approach for the
dissection of the CTD code J.B. Rodriguez-Molina, S.C.
Tseng and A.Z. Ansari. Univ. of Wisconsin-Madison and The
Genome Ctr., Madison.
D59 940.3
Messenger RNAs and cognate microRNAs
in the nucleolus P. Reyes-Gutierrez, J.C.R. Politz and T.
Pederson. Univ. of Massachusetts Med. Sch. and Fred
Hutchinson Cancer Res. Ctr.
941. DYNAMICS OF TRANSCRIPTION
Poster
D60 941.1
Organization of protein factors on the carboxy
terminal domain of RNA polymerase II in yeast M.M. Mosaheb
and S.M. Fuchs. Tufts Univ.
942. HISTONE MODIFICATIONS
Poster
D61 942.1
Regulation of acetyl-CoA homeostasis and
global histone acetylation L. Galdieri, M. Zhang and A.
Vancura. St. John’s Univ.
D62 942.2
Epigenetic deregulation of Bcl-2 leads to
apoptosis resistance in melanoma D. Sengupta, N. Avaritt
and A.J. Tackett. Univ. of Arkansas for Med. Sci.
D63 942.3
Differential expression patterns of histone
modifying enzymes in ovarian cancer in response to estradiol
and bisphenol A L. Morey, A. Weening and L. Hayes. Canisius
Col., NY.
D64 942.4
The effect of the estrogenic compounds E2
and BPA on the expression of histone modifying enzymes in
two prostate cancer models K. Burton, A. Bajdas, L. Shaw
and L. Morey. Canisius Col., NY.
D65 942.5
The effects of histone glutathionylation on
chromatin structure B.J. Blackshire. Univ. of La Verne.
D66 942.6
Programming
of
phosphoenolpyruvate
carboxykinase by maternal high fat diet may contribute to
hepatic fat accumulation in female offspring rats H. Cui, D.
Zhou, H. Chen and Y-X. Pan. Univ. of Illinois, Urbana.
D67 943.1
Investigating
the
DNA
binding
and
transactivation activity of rdyCRX as a molecular basis for
retinal dysplasia in Felis catus M. Paszek and K.A. Lipsett.
Gettysburg Col.
D68 943.2
Uncovering transcription factor binding
pockets in the tail subdomain of the human mediator complex
M. Polinkovsky, E. Sierecki, N. Giles, K. Alexandrov and Y.
Gambin. Univ. of Queensland, Australia.
944. TRANSCRIPTION ELONGATION
Poster
D69 944.1
Transcriptional properties of mammalian
Elongin A and its role in stress response M. Inoue, J. Kawauchi,
M. Fukuda, Y. Uchida, T. Yasukawa, R.C. Conaway, J.W.
Conaway, T. Aso and S. Kitajima. Tokyo Med. and Dent.
Univ., Kochi Med. Sch., Japan, Stowers Inst. for Med. Res. and
Univ. of Kansas Sch. of Med. and Kochi Med. Sch.
D70 944.2
The forward translocation position of
Escherichia coli RNA polymerase is stabilized by KCl and Mg2+
and is strongly dependent on a bridge helix N-terminal hinge
beta’ 778-GARKGL-783 Y.A. Nedialkov, F. Assaf, K. Opron
and Z.F. Burton. Michigan State Univ.
D71 944.3
Mutant versions of histone H3 are defective for
nucleosome reassembly and histone chaperone recruitment
during transcription S.J. Hainer and J.A. Martens. Univ. of
Massachusetts Med. Sch. and Hamilton Col., NY.
945. TRANSCRIPTIONAL INITIATION
Poster
D72 945.1
Tryptophan fluorescence quenching kinetic
studies of steps of open complex formation by E. coli RNA
polymerase X. Xia, J. Murray, T. Record and Z. Yang. Univ. of
Wisconsin-Madison.
946. TRANSCRIPTIONAL REGULATION
Poster
D73 946.1
Characterization of RAP1A and RAP1B
expression across cell types and identification of their core
promoter elements M.M. Painter, R.C. Augustin, A.R.
Niemela and J.L. Cruise. Univ. of St. Thomas, MN.
311
T
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BIOCHEMISTRYTUESDAY
D74 946.2
Identification of the osteo-inductive domain
within the LMP-3 protein A.B. McMichael, L. Zhou, X. Li and
P.D. Robbins. Scripps Res. Inst., Jupiter, FL.
D75 946.3
A comparative study of xanthine dehydrogenase
regulator proteins in Agrobacterium tumefaciens and
Streptomyces coelicolor S. Sivapragasam and A. Grove.
LSU.
D76 946.4
Vitamin D hormone regulates the expression of
hedgehog coreceptor genes Boc and Cdon in osteocytes V.N.
Osinski, H.C. St. John and J.W. Pike. Univ. of WisconsinMadison.
D77 946.5
Carbohydrates
downregulates
sodiumdependent neutral amino acid transporter-2 expression V.
Ortiz-Ortega, A.L. Mendez-Garcia, L.G. Noriega, N. Torres
and A.R. Tovar. Salvador Zubirán Natl. Inst. of Med. Sci. and
Nutr. and Autonomous Univ. of San Luis Potosi, Mexico City.
D78 946.6
The QA repeat domain of TCERG1 mediates
its inhibitory effect towards C/EBPα and the ability of TCERG1
to be relocalized in the nucleus N.J. Miller, S-P. Hsiao, N.A.
Timchenko and W.J. Roesler. Univ. of Saskatchewan and
Baylor Col. of Med.
D79 946.7
Modeling ToxT to explain how cholera toxicity
can be regulated by fatty acids: The 2014 Pingry SMART Team
project K. Abbott, K. Chow, B. Hong, E. Kwon, M. Newman,
J. Robinson, M. Sander, M. Sander, R. Wu, F.J. Kull and
M.E. D’Ausilio. The Pingry Sch., NJ, Dartmouth Col. and The
Pingry Sch.
D80 946.8
Biochemical and biophysical insights into the
function of the bHLH transcription factor TWIST2 C. OrengoMercado, J. Casasnovas and C.L. Cadilla. Univ. of Puerto
Rico, Med. Sci. Campus.
D81 946.9
QscR regulates expression of the formate
dehydrogenase genes in Methylobacterium extorquens AM1
R. Valdez and E. Skovran. San Jose State.
D82 946.10 Features of the RAP1A and RAP1B core
promoters: recombinant approaches to testing regulatory
element function in expression control R.C. Augustin, M.M.
Painter, A.R. Niemela and J.L. Cruise. Univ. of St. Thomas,
MN.
D83 946.11 Identification of distal regulatory regions for the
human LAT gene T.S. Finco, L. Glowka and G. Son. Agnes
Scott Col., GA.
D84 946.12 Live cell monitoring of gene modulation
provides a better understanding of gene function D. Weldon,
Y. Williams, V. Koong and K. Huryn-Selvar. EMD Millipore,
Temecula, CA.
D85 946.13 Acetyltransferase association and histone
acetylation at the Myod1 locus during myogenic differentiation
M. Hamed, S. Khilji, J. Chen and Q. Li. Univ. of Ottawa.
D86 946.14 Development and testing of affinity tag
purification vectors for a metal-dependent regulator protein
from Thermobifida fusca Z.M. Sticher, J.S. Fenton and W.R.
Novak. Wabash Col.
947. TRANSCRIPTION TERMINATION
Poster
D87 947.1
Poly(A)-dependent transcription termination
does not require poly(A) site cleavage H. Zhang and H.
Martinson. UCLA.
312
D88 947.2
Molecular basis of conversion of transcription
termination factor NusA into an antiterminator S. Mishra, S.
Mohan, S. Godavarthi and R. Sen. CDFD, Hyderabad, India.
948. PROTEIN LOCALIZATION: TARGETING AND
TRANSLOCATION
Poster
D89 948.1
Cell-free system for membrane protein
production from cultured insect cells N. Uozumi, K. Nanatani,
S. Soma, Y. Sato, K. Aizawa, T. Ezure and E. Ando. Grad.
Sch. of Engin., Tohoku Univ., Japan and Shimadzu Corp.,
Kyoto.
D90 948.2
Altered intracellular trafficking of EGFR by
extracellular glucose concentration in squamous carcinoma
cells S. Yoshimoto, H. Morita, K. Nagano, G. Sugiyama, H.
Hiroshi Takeuchi, S. Nakamura and M. Hirata. Fac. of Dent.
Sci., Kyushu Univ.
D91 948.3
The Escherichia coli Tol-Pal complex is
essential for the positioning of proteins at the cell poles M.
Rajendran, T.M. Santos and D.B. Weibel. Univ. of WisconsinMadison.
D92 948.4
Assessing the orientations of lipoprotein Pal
in the outer membrane of Escherichia coli V. MacPherson,
J. Shaw, M. Pichichero and L.V. Michel. Rochester Inst. of
Technol. and Rochester Gen. Hosp. Res. Inst.
D93 948.5
Assessing the dual orientations of vaccine
candidate P6 in nontypable Haemophilus influenzae D.
Barnard, J. Bettinger, J. Shaw, M. Pichichero and L.V.
Michel. Rochester Inst. of Technol. and Rochester Gen. Hosp.
Res. Inst.
D94 948.6
Quantifying the two populations of dual
oriented P6 in nontypable Haemophilus influenzaeand Pal in
Escherichia coli J. Shaw, R. Schmidt, V. MacPherson, M.
Pichichero and L.V. Michel. Rochester Inst. of Technol. and
Rochester Gen. Hosp. Res. Inst.
D95 948.7
Identification of the most immunogenic regions
in vaccine candidate P6 J. Bettinger, E. Newman, A. Mangan,
M. Pichichero and L.V. Michel. Rochester Inst. of Technol.
and Rochester Gen. Hosp. Res. Inst.
D96 948.8
Defining interaction interfaces important for
the establishment of cell polarity in Drosophila neuroblasts A.
Novak, J. Mauser and K. Prehoda. Minnesota State Univ.
Moorhead and Univ. of Oregon.
D97 948.9
Iron deposition and ferritin accretion in the
ovaries of the yellow fever mosquito, Aedes aegypti T. Thai,
D.L. Geiser and J.J. Winzerling. Univ. of Arizona.
D98 948.10 Experimental and computational analysis of
peroxisome protein targeting J. Berg. Univ. of Pittsburgh.
D99 948.11 Novel intracellular interactors of lysyl oxidase I.
Okkelman, A. Sukaeva, K. Kirukhina and N. Pestov. Inst. of
Bioorganic Chem., Moscow.
TUESDAYBIOCHEMISTRY
949. PROTEIN QUALITY CONTROL (PROTEIN
SYNTHESIS)
Poster
D100 949.1
Isoaspartate accumulation in creatine kinase B
in vivo and in vitro is associated with loss of enzymatic activity
A. Dimitrijevic, Z. Qin and D.W. Aswad. Univ. of California,
Irvine.
D101 949.2
Alternative autophagy alleviates A1AT-Z
accrual J. Wen, G. Dankle and K. Glenn. Yale Univ. and Univ.
of Iowa Carver Col. of Med.
D102 949.3
Febrile temperature decreases the cellsurface expression of the human ether-a-go-go-related gene
(hERG) channel by facilitating channel degradation Y. Zhao, J.
Koichopolos, T. Wang and S. Zhang. Queen’s Univ., Canada.
D103 949.4
Cross-talk between Connexin 43 and CFTR in
ER quality control S.A. Molina, N.A. McCarty and M.H. Koval.
Emory+Children’s Ctr. for Cystic Fibrosis and Airway Dis. Res.,
Emory Univ. Sch. of Med. and Emory Univ.
950. PROTEIN TARGETING AND TRANSLOCATION
Poster
D104 950.1
Mutation of serine 32 to threonine in
peroxiredoxin 6 preserves enzymatic activity but prevents
trafficking to lamellar bodies in vivo E.M. Sorokina, C.
Dodia, J-Q. Tao, S.I. Feinstein and A.B. Fisher. Univ. of
Pennsylvania.
D105 950.2
Filamin A is required for HIV-1 Vpu to promote
HIV-1 release D. Dotson, L. Liu, J. Sutton and X. Dong.
Meharry Med. Col.
D106 950.3
The N-terminal region of the Trypanosoma
brucei Tim17 is critical for mitochondrial protein import E.
Weems. Meharry Med. Col.
D107 950.4
The structure of a tail-anchor membrane
protein-binding complex reveals the regulation of Get3 by Get4
H.B. Gristick, M. Rao, J.W. Chartron, M.E. Rome, S-o. Shan
and W.M. Clemons. Caltech.
D108 950.5
Regulation
of
Ras
localization
and
cell
transformation
by
evolutionarily
conserved
palmitoyltransferases E. Young, Z-Y. Zheng, A.D. Wilkins,
H-T. Jeong, L. Min, O. Lichtarge and E.C. Chang. Baylor Col.
of Med. and Nanjing Hosp. of Traditional Chinese Med.
951. PROTEIN TURNOVER AND QUALITY CONTROL
Poster
952. UBIQUITIN PATHWAY AND TARGETING
Poster
D111 952.1
Identification of E6AP/UBE3A as a ubiquitinprotein ligase that catalyzes encephalomyocarditis virus 3C
protease ubiquitylation T. Notarianni, M. Carmody, K. Kirwin
and T.G. Lawson. Bates Col.
D112 952.2
Reactive oxygen species/neddylation is a
novel pathway of transforming growth factor-β-induced smooth
muscle cell differentiation J. Fei and S. Chen. Univ. of Georgia.
D113 952.3
Structural and biophysical analysis of UCH37:
ubiquitin recognition and binding to ADRM1 M.E. Morrow, M-I.
Kim, L.N. Paul, J.A. Ronau and C. Das. Purdue Univ.
D114 952.4
The role of a ubiquitin processing protease
in Dictyostelium development D. Plubell, A. Knotts and D.
Lindsey. Walla Walla Univ.
D115 952.5
Carbonates are a new class of deubiquitinating
enzyme inhibitors M.J. Long, A. Lawson, L. Rozhansky and
L. Hedstrom. Brandeis Univ.
D116 952.6
Molecular
mechanisms
of
substrate
degradation by the 26S proteasome revealed by CryoEM M.E.
Matyskiela, G. Lander and A. Martin. Univ. of California,
Berkeley and The Scripps Res. Inst.
953. MITOCHONDRIAL (DYS)FUNCTION AND
DISEASE
Poster
D117 953.1
Small molecule modulation of DLD diaphorase
activity to decrease reactive oxygen species production in the
mitochondria M. Mesquitta, D. Berkhowlz, M.A. Walters, G.
Isaya and J. Thompson. Mayo Clin. and Univ. of Minnesota,
Minneapolis.
D118 953.2
Membrane fluidity and lipoperoxidation of
placental mitochondria in diabetic rats M.d.C. FigueroaGarcía, C. Cortés-Rojo, A. Saavedra-Molina and R. MejíaZepeda. Univ. Michoacana de San Nicolás de Hidalgo and
UNAM, Tlalnepantla, Mexico.
D119 953.3
Macromitophagy is a longevity assurance
process that in chronologically aging yeast limited in calorie
supply sustains functional mitochondria and maintains cellular
lipid homeostasis V. Titorenko, A. Beach, V.R. Richard, A.
Leonov, A. Piano and R. Feldman. Concordia Univ., Canada.
D120 953.4
Effects of avocado oil on kidney mitochondrial
membrane potential of L-NAME-treated rats L. Hernandez
De La Paz, O. Ortiz-Avila, M. Canizal-Garcia, E. CalderonCortes, M. Clemente-Guerrero, A. Saavedra-Molina and C.
Cortes-Rojo. Univ. Michoacana de San Nicolas de Hidalgo,
Mexico.
D109 951.1
β-Hairpins as stability tags for recombinant
expression of recalcitrant small helical proteins M.E.
Lokensgard and J.J. Love. San Diego State Univ.
D110 951.2
Generation of a new monoclonal antibody
against zebrafish Insm1a J.E. Hoerter, M. Forbes-Osborne
and A. Morris. Bellarmine Univ. and Univ. of Kentucky.
313
T
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BIOCHEMISTRYTUESDAY
954. EXERCISE AND METABOLIC DETERMINANTS
OF FITNESS
Poster
Poster
D121 954.1
Maternal inheritance of circulating irisin in
humans N. Al-Daghri, O. Al-Attas, M. Alokail, K. Alkharfy,
M. Yousef, B. Vinodson, O. Amer, A. Alnaami, S. Sabico, G.
Tripathi, M. Piya, P. McTernan and G. Chrousos. King Saud
Univ., Ministry of Hlth., Riyadh, Warwick Univ., U.K. and Athens
Univ. Med. Sch.
D122 954.2
Physical activity may protect against low grade
systemic inflammation in young adults P. Escalante, D. Vera,
K. Weaver, J. Garcia and S.L. Dunn. Univ. of La Verne.
955. METABOLIC SYNDROME AND HEART DISEASE
Poster
D123 955.1
β-Actin is regulated by endothelin 1 and is not
a consistent endogenous control in aortic smooth muscle cells
from leptin-deficient mice L.S. Carmo, M.C.C. Andrade and
M. Liberman. Hosp. Israelita Albert Einstein, São Paulo.
956. MITOCHONDRIAL ROLES IN AGING AND
ATROPHY
Poster
D124 956.1
Bedrest increases burden of mitochondrial
DNA deletions in human muscle G.J. Cloutier, Y. Kraytsberg,
K. Khrapko, N. Brooks, A. Safd, R. Roubenoff and C.
Castaneda-Sceppa. Bouve Col. of Hlth. Sci., Northeastern
Univ., Beth Israel Deaconess Med. Ctr., Univ. of Stirling, U.K.
and Novartis Insts. for Biomed. Res.
D125 956.2
Mitochondrial membrane lipidome defines
yeast longevity V. Titorenko, A. Beach, V.R. Richard, A.
Leonov, A. Piano and R. Feldman. Concordia Univ., Canada.
957. MITOCHONDRIAL ROLES IN INFLAMMATION
Poster
D126 957.1
Hexane fraction of Costus afer Ker Gawl leaf
inhibited mitochondrial permeability transition, F1F0 ATPase
and scavenged nitric oxide and hydrogen peroxide G.N.
Anyasor, F.D. Onajobi, O. Osilesi and O.O. Adebawo.
Babcock Univ., Nigeria.
314
958. MONOGENIC DISEASES AND MITOCHONDRIAL
DYSFUNCTION
D127 958.1
Characterization of the mitochondrial function
and genetics in the pathogenesis of collagen VI related
disorders A. Angelin, C.S. Lin, M. Sharpley, O. Derbeneva,
P. Potluri, P. Bonaldo, P. Bernardi and D. Wallace. Children’s
Hosp. of Philadelphia Res. Inst. and Univ. of Padua.
D128 958.2
The genetic basis of mitochondrial DNA
depletion syndrome C.M. Venkataraman, M.S. Field and P.J.
Stover. Cornell Univ.
959. METABOLISM AND NUTRITION
Poster
D129 959.1
Attenuation of carbon tetrachloride toxicity in
acute hepatosteatosis induced by intake of a high carbohydrate
diet after food deprivation C.W. Ahn, D.Y. Kwon, J.A. Lee, Y.J.
Choi and Y.C. Kim. Col. of Pharm., Seoul Natl. Univ.
D130 959.2
Withdrawn.
D131 959.3
The prevalence of micronutrient deficiency
among women A. Abduldayeva, I. Smagulova and G.
Doszhanova. Kazakh Acad. of Nutr. and Astana Med. Univ.,
Kazakhstan.
D132 959.4
Inflammatory bowel disease is a disorder
of ganglioside metabolism J.J. Miklavcic, T. Hart, G.M.
Lees, K.L. Schnabl, A. Thomson, V.C. Mazurak and M.T.
Clandinin. Univ. of Alberta and Western Univ., Canada.
D133 959.5
Heavy metals and polyaromatic hydrocarbon
contaminants in smoked and fresh Clarias gariepinus from a
cultured system in Lagos, Nigeria F.I. Osuala, M.N. Igwo –
Ezikpe and B.E. Emmanuel. Univ. of Lagos, Nigeria.
D134 959.6
Effect of fasting on the neuronal Fto expression
and intracellular localization in the rat brain P. Vujovic, S.
Stamenkovic, N. Jasnic, I. Lakic and J. Djordjevic. Belgrade
Univ. Fac. of Biol.
D135 959.7
Vitamin D status and metabolism in pregnant,
lactating, and nonpregnant women consuming controlled
intakes of vitamin D H.J. Park, P.M. Brannon, A.A. West, J.
Yan, X. Jiang, C.A. Perry, O.V. Malysheva, S. Mehta and
M.A. Caudill. Cornell Univ.
D136 959.8
Effects of feeding Ricinus communis seed
meal on liver enzymes makers of albino rats N.Y. Omeh and
E.E. Ejiofor. Michael Okpara Univ. of Agr., Nigeria.
D137 959.9
Investigating effects of consuming different
protein and/or oil sources on progression and severity of
polycystic liver disease in young female PCK rats N. Nanda, K.
Maditz, C. Oldaker, R. Livengood, V. Benedito and J. Tou.
West Virginia Univ., Daniels and West Virginia Univ.
D138 959.10 Can bisphenol-A migrating from canned food
contribute to the obesity epidemic? C. Gaissert, K. Subramany
and B. Sampoli Benitez. Marymount Manhattan Col.
D139 959.11 Comparison of biological activities of the leaf
and root extracts of Smilax china L. Y.H. Kang, D.J. Kim, T.W.
Kim, K.K. Kim and M. Choe. Kangwon Natl. Univ., South
Korea.
TUESDAYBIOCHEMISTRY
D140 959.12 Antiatherosclerosis effect of pine nut oil in
HCHF diet-fed rats J.S. Lee, D.J. Kim, Y.H. Kang, T.W. Kim,
K.K. Kim and M. Choe. Kangwon Natl. Univ., South Korea.
D141 959.13 Characterization of saccharogenic mixed
grain beverages produced by various microbial species J.S.
Lee, D.J. Kim, Y.H. Kang, T.W. Kim, K.K. Kim and M. Choe.
Kangwon Natl. Univ., South Korea.
D142 959.14 Simultaneous analysis of urinary fructose and
sucrose by isotope dilution tandem LCMS A.A. Franke, L.J.
Custer and X. Li. Univ. of Hawaii Cancer Ctr.
D143 959.15 Prevention of vascular disease of vegetable
oils in HUVEC K.K. Kim, D.J. Kim, Y.H. Kang, S.M. Lee and
M. Choe. Kangwon Natl. Univ., South Korea.
D144 959.16 Investigation of potential as a functional food
material of wild herb extract through sugaring S.M. Lee, D.J.
Kim, Y.H. Kang, T.W. Kim, J.S. Lee and M. Choe. Kangwon
Natl. Univ., South Korea.
D145 959.17 Anti-diabetes effects of Smilax china L. extract
Y.H. Kang, D.J. Kim, T.W. Kim, K.K. Kim and M. Choe.
Kangwon Natl. Univ., South Korea.
D146 959.18 A study on the glucose-regulating enzyme
activities of water extracts from Korea medicinal herbs D.J.
Kim, Y.H. Kang, T.W. Kim, K.K. Kim and M. Choe. Kangwon
D147 959.19 Live-cell imaging study on anti-adipogenic and
apoptotic effects of a polyphenolic resveratrol during adipocyte
differentiation H. Ihara, M. Ogawa and Y. Magata. Wakayama
Med. Univ. and Hamamatsu Univ. Sch. of Med.
D148 959.20 Oxidized metabolites of linoleic acid mediated
hepatotoxicity as a potential mechanism of dietary unsaturated
fat and alcohol induced liver injury: in vivo and in vitro studies
H. Liu, C. Ramsden, A. Feldstein, C. McClain and I. Kirpich.
Univ. of Louisville, NIAAA, NIH, UCSD and Robley Rex VA
Med. Ctr., Louisville.
D149 959.21 Aqueous maté extract decreases the viability
human breast cancer through apoptosis and cancer repression
K. Nisbett and A. Sadik. Touro Univ. Nevada Col. of Osteo.
Med.
D150 959.22 The impact of fish-oil fatty acids on postprandial
vascular reactivity S. McManus, D. Vauzour, A. Cassidy and
A.M. Minihane. Univ. of East Anglia, U.K.
960. MITOCHONDRIA IN HEALTH AND DISEASE
Poster
D151 960.1
Impaired tafazzin-mediated remodeling of
cardiolipin does not enhance susceptibility to ischemia and
reperfusion injury K. Szczepanek, J. Allegood, H. Aluri, Y.
Hu, Q. Chen and E.J. Lesnefsky. Virginia Commonwealth
Univ. and McGuire VA Med. Ctr., Richmond.
D152 960.2
Effect of Justicia spicigera extract plant on
oxidative and nitrosative stress in hypertensive rat kidney
mitochondria E. Esquivel-Gutiérrez, M. Clemente-Guerrero,
S. Manzo-Avalos, R. Salgado-Garciglia and A. SaavedraMolina. Univ. Michoacana de San Nicolás de Hidalgo, Mexico.
D153 960.3
The role of bcl-2 proteins during chronic
glucose exposure coupled with oxidative stress K. Van Dalfsen
and V. Del Gaizo Moore. Elon Univ.
D154 960.4
Comparison of different techniques for
monitoring of mammalian cell respiration A.V. Kondrashina,
R.I. Dmitriev and D.B. Papkovsky. University Col. Cork.
D155 960.5
Effects of avocado oil in brain mitochondrial
ETC function and ROS generation in diabetic rats O. OrtizAvila, L. Hernandez-De La Paz, M. Canizal-Garcia, R.
Montoya-Perez, A. Saavedra-Molina and C. Cortes-Rojo.
Univ. Michoacana de San Nicolas de Hidalgo, Mexico.
D156 960.6
Altered mitochondrial function in epididymal
adipose tissue with advancing age C.R. Hart, G. Layec,
J.D. Trinity, G.D. Henson, R.G. Morgan, A.E. Walker, A.J.
Donato, L.A. Lesniewski and R.S. Richardson. George E.
Whalen VA Med. Ctr. and Univ. of Utah.
D157 960.7
Mitochondrial proteomes of Drosophila
melanogaster adapted to chronic hypoxic environment J. Xue,
S. Yin, G. Perkins, M.H. Ellisman, G.G. Haddad, S. Liu and
D. Zhou. UCSD, Beijing Inst. of Genomics and The Rady
Children’s Hosp., San Diego.
961. MITOCHONDRIAL DYNAMICS AND SIGNALING
Poster
D158 961.1
ATM mediates adaptive epigenetic responses
to mitochondrial stress E.A. Schroeder, B.E. Christian and
G.S. Shadel. Yale Univ.
D159 961.2
Molecular mechanism studies of mammalian
sterile20-like protein kinase 3 in mitochondrial dynamics W.
Lin and C-J. Yuan. Natl. Chiao Tung Univ., Taiwan.
962. CELL DIVISION
Poster
D160 962.1
Cytokinesis requires supervillin-mediated
binding to myosin II and synergism with anillin E.J. Luna, T.C.
Smith, P.C. Fridy, Y. Li, S. Basil, S. Arjun, R.M. Friesen, J.
Leszyk, B.T. Chait and M.P. Rout. Univ. of Massachusetts
Med. Sch. and Rockefeller Univ.
963. DISEASES OF ORGANELLE MISFUNCTION
Poster
D161 963.1
Insight into the lysosomal storage disorder
cystinosis: genetic interactions with ERS1 in Saccharomyces
cerevisiae K.E. Rickel, J.A. Simpkins and S.P. Vitiello.
Augustana Col., SD.
315
T
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BIOCHEMISTRYTUESDAY
964. INTRACELLULAR DYNAMICS
Poster
D162 964.1
ARRDC5 cooperates with ACAP4 to regulate
ARF6 activity at the cell membrane J. Zhou, H. Liu, X. Zhao,
D. Wang, F. Wang, F. Liu and X. Yao. Univ. of Sci. & Technol.
of China, Heifei and Beijing Univ. of Chinese Med.
965. MITOCHONDRIAL DYNAMICS
Poster
D163 965.1
Identification of key components involved in
mtDNA inheritance during cell division B. Camacho, C. Osman
and P. Walter. San Jose State Univ. and UCSF.
966. MITOCHONDRIAL TOXICITY
Poster
D164 966.1
Mechanism of preventing doxorubicin-induced
mitochondrial toxicity with cardiolipin-targeted peptide, SS-31
B. Quach, A. Birk and H. Szeto. Weill Cornell Med. Col.
967. CHEMICAL BIOLOGY AND ENZYME
EVOLUTION
Poster
D165 967.1
Mutant Taq polymerase recognition of 2’
modified nucleotides H.E. Chia, A. Ogonowsky, E. Hadley
and A. Leconte. Scripps Col. and Keck Sci. Dept of The
Claremont Cols.
D166 967.2
Limitations of modified substrate recognition
by Taq DNA polymerase mutants E.E. Hadley, H.E. Chia and
A.M. Leconte. Scripps Col. and Keck Sci. Dept. of Claremont
Cols.
D167 967.3
Comparative characterization of Taq DNA
polymerase mutants capable of recognizing 2’ modified
nucleotides A.M. Leconte, H.E. Chia, E.E. Hadley, A.M.
Gochi and A.M. Valencia. Keck Sci. Dept. of Claremont Cols.,
Scripps Col. and Pitzer Col.
D168 967.4
Efforts towards crystallization of Taq DNA
polymerase mutants A.M. Valencia, J.A. Kroll, M. Sazinsky
and A.M. Leconte. Pitzer Col., Claremont McKenna Col.,
Pomona Col. and Keck Sci. Dept. of Claremont Cols.
D169 967.5
The role of I614 and E615 in unnatural
substrate recognition in Taq DNA polymerase mutants A.M.
Gochi, H.J. Schultz and A.M. Leconte. Pitzer Col., Claremont
McKenna Col. and Keck Sci. Dept. of Claremont Cols.
D170 967.6
Clustering protease domains for use in directed
evolution of specificity T. Selby. Bucknell Univ.
316
D171 967.7
Identification of KASIII enzymes with novel
substrate specificities: demonstration of in vivo production of
novel ω-1 hydroxylated fatty acids using a novel KASIII S.
Garg, H. Jin, C. Stewart, M.D. Yandeau-Nelson, J. Noel and
B.J. Nikolau. Iowa State Univ. and HHMI, La Jolla.
D172 967.8
Urzymology: experimental access to the origins
of catalytic activity and translation C.W. Carter, V. Weinreb, L.
Li, M. Collier, S.N. Chandrasekaran and H. Fried. Univ. of
North Carolina at Chapel Hill.
968. MOLECULAR TOOLS FOR PROTEIN
SIGNALING
Poster
D173 968.1
Progress toward a novel pro-drug approach for
temporal manipulation of protein kinase A with a commercially
available ruthenium catalyst B. Hunt, S. Dahlen, C. Streu and
P. Mertz. St. Mary’s Col. of Maryland.
D174 968.2
Harnessing sulfinic acid reactivity to report
protein S-nitrosylation B.R. Martin. Univ. of Michigan.
D175 968.3
A protein crystallography and small molecule
informatics-based discovery engine for the development of
selective chemical probes for in vivo investigations of protein
kinases V.L. Grum-Tokars, S.M. Roy, G. Minasov, W.F.
Anderson and D.M. Watterson. Northwestern Univ., Chicago.
969. PROTEIN INTERACTIONS IN CATALYSIS
Poster
D176 969.1
Thermodynamics and kinetics of calmodulin/
roponic chimeras C-C. Wei, D. Jensen and K. Bennett.
Southern Illinois Univ. Edwardsville.
D177 969.2
Characterization of Fas receptor peptides
with calmodulin and its derivatives D. Jensen and C-C. Wei.
Southern Illinois Univ. Edwardsville.
D177A 969.3
It takes two to tango: fine-tuning of soluble
guanylate cyclase activity via protein-protein interactions and
conformational changes E.D. Garcin, F. Seeger, R. Quintyn,
A. Tanimoto, G.J. Williams, S.E. Tsutakawa, V. Wysocki
and J.A. Tainer. Univ. of Maryland Baltimore County, The Ohio
State Univ. and Lawrence Berkeley Natl. Lab.
970. BIOSYNTHESIS OF COMPLEX MOLECULES
Poster
D178 970.1
The role of bacterial cell wall dimers in the
innate immune response L.A. Genova, J. Melnyk, V. Mohanan
and C.L. Grimes. Univ. of Delaware.
D179 970.2
Synthesis of muramic acid derivatives to
investigate the promiscuity of bacterial cell wall biosynthetic
enzymes D.J. Kenny and C.L. Grimes. Univ. of Delaware.
TUESDAYBIOCHEMISTRY
D180 970.3
Screening
of
secondary
metabolites
biosynthesized with novel amino acid carrier protein system
K. Matsuda, F. Hasebe, T. Tomita, Y. Shiwa, H. Yoshikawa,
K. Shin-ya, T. Kuzuyama and M. Nishiyama. Univ. of Tokyo,
Tokyo Univ. of Agr. and AIST, Tokyo.
D181 970.4
Characterization of glycosyltransferases in the
biosynthetic pathway of capsular polysaccharide A S. Sharma
and J.M. Troutman. Univ. of North Carolina at Charlotte.
971. CHEMICAL BIOLOGY OF CELL DEATH
Poster
D182 971.1
Identification and characterization of novel
granzyme in fish Y. Matsuura, T. Yabu, Y. Shibasaki, H.
Shiba, T. Moritomo and T. Nakanishi. Nihon Univ.
D183 971.2
Investigations of the specificity and promiscuity
of receptors within the BCL-2 protein family K.J. Carlson. Univ.
of Arizona.
972. CHEMICAL PROBES AND THEIR USE IN
IDENTIFYING NEW THERAPEUTIC TARGETS
Poster
D184 972.1
Antioxidant and antiradical activity of essential
oils of Kazakhstan plants A. Kazbekova, K. Moldabekov, T.
Seitembetov, A. Zeinuldina and E. Dalenov. Astana Med.
Univ., Kazakhstan.
D185 972.2
Fluorescent biosensors for probing CDK4/
cyclin D activity and developing non-ATP pocket Inhibitors for
melanoma, lung cancer and lymphoma M.C. Morris, C. Prevel,
M. Pellerano and T.N.N. Van. IBMM, CNRS 5247, Montpellier.
D186 972.3
EU-OPENSCREEN: novel chemical tool
compounds for molecular biologists B. Stechmann. Leibniz
Inst. for Molec. Pharmacol., Berlin.
D188 972.5
Towards the functional characterization and
inhibition of hydrolase enzymes in mycobacteria H.V. Patel
and J.C. Seeliger. Stony Brook Univ.
D189 972.6
Unnatural covalent bond formation inside and
between proteins through proximity-enhanced reaction Z.
Xiang, H. Ren, Y.S. Hu, I. Coin, J. Wei, H. Cang and L. Wang.
Salk Inst. and JadeBio Inc., La Jolla.
973. CHEMISTRY AND CELL BIOLOGY OF NATURAL
PRODUCTS
Poster
D191 973.2
Characterization
of
active
compounds
produced in the biotransformation of metabolites in kombucha
tea K.J. Seehusen, M.A. Villeneuve and F.M. Mann. Winona
State Univ.
D192 973.3
Anti-inflammatory compounds from Cordyceps
bassiana T-W. Kim, D-H. Yoon, J-Y. Cho and G-H. Sung.
Kangwon Natl. Univ., Sungkyunkwan Univ. and Rural Develop.
Admin., Suwon-si, South Korea.
D193 973.4
Transcriptional rewiring and spatiotemporal
expression of evolutionarily conserved redox active molecules
during bacterial community morphogenesis R.S. Gokhale, P.
Verma, A.A. Anand and A.K. Singh. CSIR-Inst. of Genomics
& Integrat. Biol., Delhi, Natl. Inst. of Immunol., Delhi and CSIRNorth East Inst. of Sci. and Technol., Jorhat, India.
D194 973.5
Characterizing the spectral properties of
(-)-epigallocatechin 3-O-gallate fluorescence in solvents of
different polarity M.N. Young, E. Petroff and V. Snitsarev.
Montclair State Univ.
D195 973.6
Antibacterial activities of new coumarine
heteroaryl derivatives S. Govori Odai, A. Haziri, S. Spahiu
and H. Ibrahimi. Univ. of Pristina and Reg. Water Co.,
Prishtina, Kosovo.
974. MEMBRANE PROTEINS AS DRUG TARGETS
Poster
D196 974.1
Cardiac glycosides with selectivity for the
α2 isoform of NaK- ATPase A. Katz, D. Tal and S. Karlish.
Weizmann Inst. of Sci., Rehovot.
D197 974.2
Reversal of multidrug resistance by novel
inhibitors of human P-glycoprotein in cell culture C.A. Follit,
F.K. Brewer, P.D. Vogel and J.G. Wise. Southern Methodist
Univ.
D198 974.3
Inhibition
of
energy
transduction
in
P-glycoprotein F.K. Brewer, C.A. Follit, I.R. Rossi, C.S.
Wheelis, J.G. Wise and P.D. Vogel. Southern Methodist Univ.
D199 974.4
Identification and characterization of the
molecular interactions of persistent organic pollutants with the
multidrug resistance transport protein ABCB1 S.C. Nicklisch,
L. Bonito, S. Sandin and A. Hamdoun. Scripps Instn. of
Oceanography.
D200 974.5
Dynamic elucidation of drug transport
pathways in human P-glycoprotein J.W. McCormick, P.D.
Vogel and J.G. Wise. Southern Methodist Univ.
D201 974.6
Tetraiodothyroacetic acid (tetrac) receptor on
integrin αvβ3: tetrac blocks activation of the integrin response
to tumor cell irradiation J.T. Leith, A.H. Hercbergs, H-Y. Lin,
S.A. Mousa, H-Y. Tang and P.J. Davis. Rhode Island Nuclear
Sci. Ctr., Cleveland Clin., Albany Col. of Pharm. and Hlth. Sci.
and Albany Med. Col.
D202 974.7
Regulation of ecto-NTPDase I gene expression
in Trypanosoma cruzi N.L.D.S. Gomes, V.E. Vidal and O.C.
Moreira. Oswaldo Cruz Fndn. Rio de Janeiro.
D190 973.1
Lingonberry
(Vaccinium
vitis-idaea)
anthocyanins protect cardiomyoblasts against ischemiareperfusion injury C.K. Isaak, K. O and Y.L. Siow. Univ. of
Manitoba, Canadian Ctr. for Agri-Food Res. in Hlth. and Med.
and Agr. and Agri-Food Canada, Winnipeg.
317
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BIOCHEMISTRYTUESDAY
975. MODE OF ACTION OF BIOACTIVE NATURAL
PRODUCTS
976. NEW TARGETS FOR DRUG DISCOVERY:
ANTIBACTERIALS
Poster
Poster
D203 975.1
Lipophilic
natural
compounds
(n-3
polyunsaturated fatty acids) modulate plasma membrane
organization in mouse CD4+ T cells T.Y. Hou, R. Barhoumi,
G.M. Rivera, D.M. McMurray and R.S. Chapkin. Texas A&M
Univ. and Texas A&M Univ. Hlth. Sci. Ctr.
D204 975.2
Re-evaluation of desmethyl, desaminoPateamineA targeting of eukaryotic translation initiation factor
4F S.S. Kommaraju, J. Aulicino, J. Li, M. Zhu, D. Romo and
W-K. Low. St. John’s Univ. and Texas A&M Univ.
D205 975.3
Kinetics and molecular dynamic modeling
of a potent and selective marine natural product inhibitor of
human cathepsin L B.W. Miller, A. Friedman, H. Choi, J.A.
McCammon, V. Hook and W. Gerwick. UCSD.
D206 975.4
Inhibitory effects of pentagalloyl glucose from
winged sumac (Rhus copallinum) on albumin glycation and the
formation of advanced glycation endproducts H. Ma, W. Liu,
S.P. Navindra and J.A. Dain. Univ. of Rhode Island.
D207 975.5
The licorice (Glycyrrhiza glabra) root extract
alleviated TCDD-induced toxicity in primary rat hepatocytes X.
Chu, J.F. dela Cruz and S.G. Hwang. Hankyong Natl. Univ.,
South Korea.
D208 975.6
Isolation and characterization of a novel class
of potent anti-HIV proteins from an Australian soft coral K.
Ramessar, C.Y. Xiong, L.H. Krumpe, R.W. Buckheit, J.
Wilson, J.B. McMahon and B.R. O’Keefe. NIH at Frederick
and ImQuest BioSci., Frederick, MD.
D209 975.7
Effect of a combined fraction of protease
inhibitor and lectins on hematopoietic system in rats U.
Moreno-Celis, R. Ferriz-Martinez, V. Andrade-Portillo, J.
Lopez-Martinez, P. Aranda-Vargas, H. Noriega-Giron, M.D.J.
Guerrero-Carrillo, A. Blanco-Labra, A.J. Rodriguez-Mendez
and T. Garcia-Gasca. Autonomous Univ. of Queretaro, Mexico
and CINVESTAV, Irapuato.
D210 975.8
Investigation of potential topoisomerase I
inhibitors from indigenous natural products in southwestern
region of Nigeria O. Magbagbeola, A. James, S. Odesanmi,
T.A. Samuel and T. Oshodi. Col. of Med., Univ. of Lagos.
D211 975.9
Bioactivity guided isolation of a novel protein
from Moringa oleifera with antimicrobial activity S. Ahmed and
A. Jamil. UCSD and Univ. of Agr. Faisalabad.
D212 975.10 Pomegranate
(Punica
granatum)
fruit
polyphenols, punicalagin, ellagic acid and gallic acid, inhibit
formation of advanced glycation endproducts by scavenging
reactive carbonyl species W. Liu, H. Ma, J.A. Dain and N.P.
Seeram. Univ. of Rhode Island.
D213 976.1
The multidrug resistance IncA/C transferable
plasmid encodes a novel domain swapped dimeric disulfide
isomerase F. Kurth, P. Lakshmanane, S. Neyer, M.A.
Schembri and J.L. Martin. Univ. of Queensland, Australia.
D214 976.2
Development of selective inhibitors against
homoserine transacetylase — a novel target for drug
development B. Thangavelu, A. Pavlovsky and R.E. Viola.
Univ. of Toledo.
D215 976.3
Synthesis and characterization of a chitosan
derivative J.S. Lee, A.P. Duncan, S. Townsend and S.M.
Baker. Harvey Mudd Col. and Synedgen Inc., Claremont.
D216 976.4
Identification of an antifungal peptide from
hemolymph of an insect, Manduca sexta Q. Alsouhail, Y.
Hiromasa and M.R. Kanost. Kansas State Univ.
D217 976.5
Characterization and complementation of
a potential novel phenotype for Saccharomyces cerevisiae
PHO13 A.U. Gehret, K. Blake, J. Edwards and S.F.
O’Handley. Natl. Tech. Inst. for the Deaf, RIT and Rochester
Inst. of Technol.
D218 976.6
An investigation of novel AMPs V.R.
Greenberger and R. Stevens-Truss. Kalamazoo Col.
977. NEW TARGETS FOR DRUG DISCOVERY:
NUCLEAR HORMONE RECEPTORS
Poster
D219 977.1
Intrinsically disordered N-terminal domain of
the steroid receptors: a promising target for endocrine-based
therapeutics R. Kumar and S.H. Khan. Commonwealth Med.
Col., PA.
D220 977.2
High-throughput screen for inhibitors of
androgen receptor-RUNX2 interaction in prostate cancer W.
Vuong, B.Y. Tew, G. Little, B. Frenkel and J.O. Jones. City
of Hope Natl. Med. Ctr. and Univ. of Southern California.
978. NUCLEIC ACID- SMALL MOLECULE
INTERACTIONS
Poster
LAST DAY TO
VISIT EXHIBITS
Tuesday, April 29
9:00 AM – 4:00 PM
318
D221 978.1
Human cathelicidin hCAP-18/LL-37 expression
and subcellular localization in LNCaP and PC3 cell line models
of prostate cancer: effects on growth, migration, and invasion
S.A. Stone, M.L. Craig and P.D. Deeble. Mary Baldwin Col.,
VA.
D222 978.2
Investigation of the interaction between human
cathelicidin LL-37 and CpG DNA M. Radford, I. Avelsgard
and M.L. Craig. Mary Baldwin Col., VA.
TUESDAYBIOCHEMISTRY
D223 978.3
Thermodynamic characterization of the
interaction between the antimicrobial peptide LL-37 and DNA
oligonucleotides M.L. Craig, M. Radford, T. Nguyen and I.
Avelsgard. Mary Baldwin Col., VA.
979. PROTEIN-SMALL MOLECULE INTERACTIONS
Poster
D224 979.1
Dihydroxyacetone disturbs collagen fibril
formation due to side chain modifications by glycation W. Liu,
G.W. Dombi and J.A. Dain. Univ. of Rhode Island.
D225 979.2
Affinity extraction of proteins from acidic
environments K.E. Teichert, B.B. Stocks and J.R. Engen.
Northeastern Univ.
D226 979.3
Characterizing the effect of porcupine on
neural tube closure S. Feeney, L. Galli, G. Pay and L. Burrus.
San Francisco State Univ.
D227 979.4
Supramolecular interactions between peptides
and a glycouril-based molecular clip: a computational study S.
Elsarrag and R.K. Zachary. Mary Baldwin Col., VA.
D228 979.5
Protein-protein interactions between CIB1 and
novel integrin binding partners: structural and thermodynamic
basis of CIB1 promiscuity T.C. Freeman, J.L. Black, H.G.
Bray, O. Dagliyan, Y.I. Wu, A.C. Tripathy, N.V. Dokholyan,
T.M. Leisner and L.V. Parise. Univ. of North Carolina at
Chapel Hill.
980. TARGET IDENTIFCATION AND PATHWAY
MINING
Poster
D229 980.1
Suppression
of
NF-κB
by
dehydroxymethylepoxyquinomicin through reactive oxygen
species and unfolded protein response S. Nakajima, K.
Umezawa and M. Kitamura. Univ. of Yamanashi and Aichi
Med. Univ. Sch. of Med., Japan.
D230 980.2
Functional genomic elucidation of nicotinic acid
catabolism in Bacillus niacini towards a metabolic engineering
approach to environmental remediation Z.H. Harvey and M.J.
Snider. The Col. of Wooster.
981. OMICS, SYSTEMS BIOLOGY AND THEIR
TRANSLATIONAL APPLICATIONS
Poster
D231 981.1
Controlling low rates of terminal cell
differentiation through noise and ultra-high feedback M. Teruel,
R. Ahrends, A. Ota, K. Kovary and B.O. Park. Stanford Univ.
D232 981.2
Elucidation of cellular signaling triggered
by Francisella infection by comparative phosphoproteomic
analysis C. Ansong, E.S. Nakayasu, R. Tempel, F. Heffron,
R.D. Smith and J.N. Adkins. Pacific Northwest Natl. Lab.,
Purdue Univ. and Oregon Hlth. & Sci. Univ.
D233 981.3
Sirtuin regulation of lysine acylation targets
diverse metabolic networks in hepatic mitochondria M. Rardin,
W. He, A. Sahu, Y. Nishida, E. Verdin and B.W. Gibson. Buck
Inst., Novato, CA and Gladstone Insts. and UCSF.
D234 981.4
Systems-level analysis of xylose fermentation
by experimentally-evolved Saccharomyces cerevisiae T.K.
Sato, L. Parreiras, I. Ong, R. Avanasi, Y. Zhang, A. Higbee,
D. Keating, J. Coon, A.P. Gasch and R. Landick. Univ. of
Wisconsin-Madison.
D235 981.5
Targeted and multiplexed quantitation of CSF
proteins by MRM and labeled peptide standards A.J. Percy,
A.G. Chambers, J. Yang, D.B. Hardie and C.H. Borchers.
UVic-Genome BC Proteomics Ctr., Canada.
D236 981.6
Aerospace medical factor gene expression
patterns in live subjects persist in aviation accident victims
within muscle, blood, and brain D.M. Burian, D.M. Williams,
A. Budd, V.L. White and D.C. Hutchings. FAA, Oklahoma
City, Univ. of Oklahoma and Cherokee Nation Bus., Catoosa,
OK.
D237 981.7
Comprehensive cancer cell proteomics: a
global counterpoint to genomic techniques C.E. Bakalarski, S.
Lianoglou, R. Neve, M. Yu, S. Selvaraj, A. Possematto, S.
Beausoleil, P. Yue, D. Dornan, R. Bourgon, W. Forrest and
D. Kirkpatrick. Genentech Inc. and Cell Signaling Technol.,
Danvers, MA.
D238 981.8
Protein quantification in dried blood spots
by MRM mass spectrometry A.G. Chambers, A.J. Percy, J.
Yang and C.H. Borchers. Univ. of Victoria, Canada.
D239 981.9
Development of peptidomic assays for
discovery of endogenously processed peptides from the
healthy and juvenile idiopathic arthritis human synovial fluid
C.C. Clement and L. Santambrogio. Albert Einstein Col. of
Med.
D240 981.10 All-ambient processing of human blood
samples: complete RNA and DNA stabilization with an
automated workflow V. Liberal, J. Muller-Cohn, R. Muller and
S. Whitney. Biomatrica Inc., San Diego.
D241 981.11 Transient intrauterine ischemia duringmidgestation results in postnatal abnormalities in formation of
neocorticalcircuit elements S. Sandhu, M. Kraushar, S.
Wijeratne and M-R. Rasin. Robert Wood Johnson Med. Sch.
and Rutgers, The State Univ. of New Jersey, Piscataway.
982. METABOLOMICS
Poster
D242 982.1
Integrative analysis of microbiome and
metabolome in mouse model simulating features of posttraumatic stress disorder A. Gautam, B. Sowe, D. Donohue, R.
Kumar, S. Muhie, N. Chakraborty, A. Hoke, R. Hammamieh
and M. Jett. U.S. Army Ctr. for Envrn. Hlth. Res. and Leidos
Biomed. Res. Inc., Frederick, MD.
D243 982.2
Quantitative lc-ms/ms analysis of cytoplasmic
bacterial cell wall biosynthesis intermediates: application to
vancomycin resistance VRE H. Vemula, S. Putty, S. Bobba
and W. Gutheil. Univ. of Missouri-Kansas City Sch. of Pharm.
D244 982.3
Metabolomic analysis of maternal energy
metabolism A. Rajaee, A. Murphy and B.J. Koos. UCLA.
D245 982.4
Dephosphorylation of acyl-CoAs in the rat
ischemic heart G. Zhang, Q. Li, J.M. Berthiaume and M.
Kemerer. Case Western Reserve Univ.
319
T
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BIOCHEMISTRYTUESDAY
D246 982.5
Compartmentation of azelate and glutarate
metabolism in rat liver Z. Jin, K. Tomcik, F. Bian, H.
Brunengraber and G. Zhang. Case Western Reserve Univ.
983. OMICS AND THE DEVELOPMENT OF
PERSONALIZED MEDICINE
Poster
D247 983.1
Whole exome sequencing analysis of interparticipant cortisol response: strategies for matching phenotype
to genotype P.J. Murphy and K.M. Biette. Seattle Univ. and
Harvard Med. Sch.
984. FUNCTIONAL PROTEOMIC STUDIES
Poster
D248 984.1
Evaluating the effect of formalin fixation on
mass spectrometry-based proteomic profiling J. Atwood, D.
Neumann, E. Dammer, D. Duong, C. Dunn and N. Seyfried.
Omni Intl., Kennesaw, GA and Emory Univ.
D249 984.2
Antigens with the potential to differentiate
between acute and chronic phases of Schistosoma mansoni
V.S. Moraes, J.M.F. Siqueira, P.M.Z. Coelho and R.F.Q.
Grenfell. Univ. of São João del Rei and Res. Ctr. René Rachou,
Brazil.
D250 984.3
The human kinase-substrate phosphorylation
network rewired by genetic polymorphisms is heavily associated
with cancers Y. Xue, Y. Wang and Z. Liu. Huazhong Univ. of
Sci. and Technol.
985. ELECTROPHORESIS
Poster
D251 985.1
Microfludic separation and electrochemical
detection of neurotransmitters using a portable Lab-on-a-Chip
device N. Maughan and S. Gamagedara. Hartwick Col., NY.
986. GLOBAL ANALYSIS OF DISEASE
Poster
D252 986.1
Genesis of antibiotic resistance (AR) I:
monitoring of microbial pathogens with AR by Texas Clean
Water Program in Rio Grande Basin including Amistad
Reservoir S. Kannan, A. Iracheta,, B. Jimenez,, L. Lopez,,
K. Martinez, J. Amezcua and P. Subburaj. Southwest Texas
Junior Col., Eagle Pass.
320
D253 986.2
Genesis of antibiotic resistance II: monitoring
of antibiotics and their metabolic breakdown products in the
Rio Grande River water by United States Geological Survey
S. Kannan, C. Villarreal, M. Atchico, M. Bonilla, M. Dingler
and P. Subburaj. Southwest Texas Junior Col., Eagle Pass.
D254 986.3
Genesis of antibiotic resistance (AR) III:
trifling risk of AR pathogens induced infectious diseases from
regulated concentrated animal feeding operations S. Kannan,
L. Hernandez, A. Herrera, B. Jimenez, M. Miller, P. Perales,
C. Reyna and P. Subburaj. Southwest Texas Junior Col.,
Eagle Pass.
D255 986.4
Genesis of antibiotic resistance IV: limited
control measures in eradication of vector borne and zoonotic
diseases in southwestern border regions of United States and
Mexico S. Kannan, M. Salinas, E. Trevino, K. Martinez, A.
Iracheta and P. Subburaj. Southwest Texas Junior Col., Eagle
Pass.
D256 986.5
Genesis of antibiotic resistance V: transport
of antibiotic medication across United States - Mexico border
regulated by federal agencies S. Kannan and P. Subburaj.
Southwest Texas Junior Col., Eagle Pass.
D257 986.6
Genesis of antibiotic resistance VI: monitoring
of water quality for antibiotics, its metabolic breakdown
products in the Texas Clean Rivers Program by the Texas
Commission on Environmental Quality and also by the Texas
Water Development Board S. Kannan, J. Castillo, C. Estrada
and P. Subburaj. Southwest Texas Junior Col., Eagle Pass.
D258 986.7
Genesis of antibiotic resistance VII:
implementation of unused prescription antibiotics/antimicrobial
recycling and incidence of antibiotic resistant bacterial
infections in Texas S. Kannan, J.F. Amezcua, T. Harbison,
L. Hernandez and P. Subburaj. Southwest Texas Junior Col.,
Eagle Pass.
D259 986.8
Genesis of antibiotic resistance VIII: monitoring
of non-therapeutic use of antibiotics in biomedical, agricultural
- livestock and pharmaceutical research and development
process S. Kannan, R. Lehler, M. Miller and P. Subburaj.
Southwest Texas Junior Col., Eagle Pass.
D260 986.9
Genesis of antibiotic resistance IX: monitoring
of antibiotics, its metabolic break down intermediates by the
United States - Centers for Disease Control and Prevention
S. Subburaj, M. Dingler, T. Harbison, E. Carrillo and P.
Subburaj. Southwest Texas Junior Col., Eagle Pass.
D261 986.10 Genesis of antibiotic resistance X: cross
border procurement and disposal practices of antibiotics in Rio
Grande Valley S. Kannan and P. Subburaj. Southwest Texas
Junior Col., Eagle Pass.
987. MASS SPECTROSCOPY
Poster
D263 987.2
Determination of Rac inhibitor Ehop-016 in
mouse plasma by ultra-performance liquid chromatography
tandem mass spectrometry T.W. Humphries-Bickley, F.
Corujo, L. Castillo-Pichardo, E. Hernandez-O’Farrill, C.
Vlaar, J. Rodriguez-Orengo and S. Dharmawardhane. Univ.
of Puerto Rico Med. Sci. Campus,Res. Fndn. de Diego, San
Juan and Univ. Central del Caribe, PR.
TUESDAYBIOCHEMISTRY
988. MATHEMATICAL BIOLOGY
992. HEAVY METALS ROCK
Poster
Poster
D264 988.1
Altered RAPD polymorphisms in Cordyceps
sinensis analyzed with amplicon density-weighted algorithms
J-S. Zhu, L. Ni, Y. Yao, L. Gao, Y. Li, S. Ma, Z. Wu, N. Tan
and J-Y. Wu. Hong Kong Polytech Univ., NS Ctr. for Anti-aging
Res., Provo, UT, NS Center for Anti-aging Research, UCSD,
Pharmanex Beijing Pharmacol. Ctr., Qinghai Acad. of Animal
Husbandry Vet. Sci., China and Hong Kong Polytech Univ.
989. NEW MOLECULAR AND CELLULAR IMAGING
AGENTS
Poster
D265 989.1
A novel light, oxygen, or voltage fluorescent tag
for structural and biophysical analysis of DNA repair enzymes
M.J. Robertson, R. Hatherill, J.O. Fuss and J.A. Tainer. Del
Mar Col., TX, Berkeley Natl. Lab. and The Scripps Res. Inst.
990. RECOMBINANT DNA TECHNOLOGY
Poster
D266 990.1
New immunological assays for diagnosis of
Schistosoma mansoni for clinical acute and/or chronic forms
R.F. Grenfell Queiroz, V. Silva-Moraes, D.A. Harn and
P.M.Z. Coelho. Oswaldo Cruz Fndn., Belo Horizonte and Univ.
of Georgia.
991. REGULATORY NETWORKS
Poster
D267 991.1
Methylation of hippo pathway genes in bone,
kidney, breast and prostate cancer cells M.S. Alokail and A.M.
Alenad. King Saud Univ. and Univ. of Southampton.
D268 991.2
Optimizing two-component light-switchable
systems for controlling gene expression in Escherichia coli D.
Stork, S. Schmidl and J. Tabor. Harvey Mudd Col. and Rice
Univ.
D269 992.1
New copper binding components of blood
plasma M. Dalphin, D. Salazar, S. Paik, T.Z. Kidane, C. Vulpe,
K. Page and M.C. Linder. California State Univ., Fullerton and
Univ. of California, Berkeley.
D270 992.2
Insulin signaling and copper homeostasis are
functionally linked in 3T3-L1 adipocytes H. Yang, N. Dhawan,
K. Ivy, J.H. Kaplan and S. Lutsenko. Johns Hopkins Univ.
and Univ. of Illinois at Chicago.
993. MOVIN’ IN THE LIPID: MEMBRANE PROTEIN
DYNAMICS
Poster
D271 993.1
Dynamics of the general secretory system
viewed in near-native conditions via atomic force microscopy
G. King, R.R. Sanganna Gari, N.C. Frey, C. Mao and L.L.
Randall. Univ. of Missouri-Columbia.
D272 993.2
Probing herpesvirus membrane glycoprotein
interactions using proximity biotinylation S.A. Connolly, M.
Lajko and A.F. Haddad. DePaul Univ.
994. MEMBRANE TRANSPORT
Poster
D273 994.1
A comparative survey of the impact of NHE1
phosphorylation on pHi and cell motility A. Zamit, M. Strong,
M. Hovde, M. Wallert and J.J. Provost. Univ. of San Diego
and Minnesota State Univ. Moorhead.
D274 994.2
Understanding mechanisms of multidrug
resistance with guidance from evolution T. Gokirmak, J.P.
Campanale, L.E. Shipp, G.W. Moy and A. Hamdoun. Scripps
Instn. of Oceanography, UCSD.
995. METAL HOMEOSTASIS
Poster
D275 995.1
Ferroportin deficiency impairs manganese
metabolism in flatiron mice Y.A. Seo and M. WesslingResnick. Harvard Univ. Sch. of Publ. Hlth.
D276 995.2
The role of multicopper ferroxidases in
mammalian iron homeostasis B.K. Fuqua, Y. Lu, D. Darshan,
D.M. Frazer, S.J. Wilkins, K.E. Page, C.D. Vulpe and G.J.
Anderson. Univ. of California, Berkeley and QIMR Berghofer
Med. Res. Inst., Brisbane.
321
T
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BIOCHEMISTRYTUESDAY
D277 995.3
Overexpression of the novel gene CIA7 in
Chlamydomonas reinhardtii R. Pedraza and R. Ynalvez.
Texas A&M Intl. Univ.
D278 995.4
The effect of toxic heavy metals, Hg and
Cd on the mRNA expression levels of the novel gene CIA7
of Chlamydomonas reinhardtii A. Sanchez and R. Ynalvez.
Texas A&M Intl. Univ.
996. METAL TRANSPORT AND CELLULAR
DISTRIBUTION
Poster
D279 996.1
Factors affecting manganese accumulations
in gill mitochondria of Crassostrea virginica T. Shoneye, A.
Nuhar, E.J. Catapane and M.A. Carroll. Medgar Evers Col.,
Brooklyn.
D280 996.2
Direct uptake of copper from plasma
ceruloplasmin by cells that do and do not express CTR1 R.
Vargas, D. Ramos, D. Mar, M. Ishida, K.J. Lee, M.C. Linder
and A. Montgomery. California State Univ. Fullerton.
D281 996.3
Intestinal divalent metal-ion transporter-1 is
critical for intestinal iron absorption but not that of copper A.
Shawki, S.R. Anthony, M.A. Engevik, E.J. Niespodzany,
R.T. Worrell and B. Mackenzie. Univ. of Cincinnati.
D282 996.4
Evidence for an interdomain flavin binding site
in Steap (six-transmembrane epithelial antigen of the prostate)
family metalloreductases associated with iron homeostasis
and insulin resistance M.D. Kleven, G.H. Gauss, M. Fleming
and C.M. Lawrence. Montana State Univ. and Children’s
Hosp. and Harvard Med. Sch.
D283 996.5
Cellular zinc levels are influenced by the
interaction between the mucolipidosis IV-associated TRPML1
protein and TMEM163 protein J. Silva, L.C. Basilio, T. Hart, J.
Tringali and M.P. Cuajungco. California State Univ., Fullerton.
997. STRUCTURE AND FUNCTION OF TRANSPORT
PROTEINS AND CHANNELS
Poster
D284 997.1
Investigating the domain motions of an
asymmetric ABC transporter P. Tieleman, V. Corradi, G.
Singh and M. Seeger. Univ. of Calgary, Canada and Univ. of
Zurich.
D285 997.2
Structural and functional characterization of a
heavy metal detoxifying ABC transporter J.Y. Lee, J.G. Yang,
D. Zhitnitsky, O. Lewinson and D.C. Rees. HHMI/Caltech
and Technion-Israel Inst. of Technol., Haifa.
D286 997.3
Identification of trafficking motifs in the
C-terminus of the cystine/gluatamate exchanger, System xcN. Ladd, E. Unterbrink, A. Georges, S. Lang and L. Chase.
Hope Col., MI.
D287 997.4
Identification of essential residues in the
extracellular region of the epithelial sodium channel C.N.
Berman and R.E. Booth. Texas State Univ.
322
D288 997.5
Binding affinity of epithelial sodium channel
subunits and peptides measured through surface plasmon
resonance A. Gonzalez, G. Peltier, R.E. Booth and W. David.
Texas State Univ.
D289 997.6
ABC transporters and uptake in Haemophilus
influenzae H.W. Pinkett. Northwestern Univ.
D290 997.7
Molecular taxis: impact of candidate genes on
epithelial sodium channel function J.D. Hall and R.E. Booth.
Texas State Univ.
D291 997.8
Identification of accessory proteins necessary
for epithelial sodium channel function B. Sterling and R.E.
Booth. Texas State Univ.
D292 997.9
Single molecule studies of the E.coli protein
export system R.R. Sanganna Gari, N. Frey, C. Mao, L.
Randall and G. King. Univ. of Missouri-Columbia.
D293 997.10 Cross-linking study of membrane subunits K,
L, M and N in E. coli complex I S.B. Vik, S. Zhu and A. Tursun.
Southern Methodist Univ.
998. CHEMICAL PROBES AND PHARMACOLOGY OF
LIPID SYSTEMS
Poster
D294 998.1
Reprogramming
of
hepatic
lipoprotein
metabolism by small molecule inducers of TRIB1 expression
M. Nagiec, A. Skepner, J. Negri, M. Eichhorn, E. Comer,
G. Muncipinto, K. Musunuru, A. Subramanian, C. Clish, J.
Duvall, M. Foley, J. Perez and M. Palmer. Broad Inst. of MIT
and Harvard and Harvard Univ.
D295 998.2
Specific
nonlipid
agonists
of
the
lysophosphatidic acid type 2 GPCR with subnanomolar
potency mitigate radiation injury E. Szabo, R. Patil, J. Fells,
D. Norman, A. Balogh, D. Miller and G. Tigyi. Univ. of
Tennessee Hlth. Sci. Ctr.
999. LIPID SIGNALING AND SECOND MESSENGERS
Poster
D296 999.1
Lactosylceramide
promotes
hypertrophy
through ROS generation and activation of ERK1/2 in
cardiomyoctes S. Mishra and S. Chatterjee. Johns Hopkins
Med. Instns.
D297 999.2
Phosphatidylinositol-4-phosphate
synthesis
and turnover spans multiple membrane compartments G.
Hammond, M.P. Machner and T. Balla. NICHD, NIH.
D298 999.3
Role of lysophosphatidic acid in traumatic
brain injury: anti-LPA antibodies are neuroprotective after
experimental TBI J. Wojciak, R. Sabbadini, P. Crack, C.
Morganti-Kossmann, M. Zhang, A. Pebay, A. Conquest and
A. Morris. Lpath Inc., San Diego, Univ. of Melbourne, Monash
Univ., Florey Inst. of Neurosci. and Ment. Hlth., Monash Univ.,
Australia and Univ. of Kentucky.
TUESDAYBIOCHEMISTRY
D299 999.4
Discovery of a lipid deacetylase (AADACL1)
as a novel regulator of platelet activation S.P. Holly, J.W.
Chang, W. Li, S. Niessen, R.M. Phillips, R. Piatt, J.L. Black,
M.C. Smith, Y. Boulaftali, A.S. Weyrich, W. Bergmeier, B.F.
Cravatt and L.V. Parise. Univ. of North Carolina at Chapel Hill,
The Scripps Res. Inst. and Univ. of Utah.
1000.LIPIDS AND CONTROL OF GENE EXPRESSION
Poster
D300 1000.1 Induction of VEGF expression in monocytes
by alpha-tocopherol and alpha-tocopheryl phosphate via
PI3Kgamma/Akt
and
hTAP1/SEC14L2-mediated
lipid
exchange J-M. Zingg, A. Azzi and M. Meydani. Tufts Univ.,
Boston.
D301 1000.2 Lipid production in Chlorella protothecoides B.
Sizemore and R. Waikel. Eastern Kentucky Univ.
D302 1000.3 Differential regulatory response for the Δ9
desaturase in Saccharomyces cerevisiae based on fatty acid
species and intracellular amount C. Schriemer, M. Willey, M.
Ochs, L. Hillers and V. McDonough. Hope Col., MI.
1001.LIPIDS IN INFLAMMATION AND STRESS
Poster
D303 1001.1 Cholesterol homeostasis in mouse bone
marrow-derived macrophages from RA- and SLE-like murine
models: a possible mechanism for atherogenesis I. Voloshyna,
M.J. Littlefield, I. Teboul, A.M. Archer, T. Palaia, L. Ragolia,
H.R. Perlman and A.B. Reiss. Winthrop Univ. Hosp., Mineola,
NY, Northwestern Univ. Feinberg Sch. of Med. and Winthrop
Univ. Hosp.
D304 1001.2 Palmitate-induced alterations in phospholipid
composition promote ER stress and cellular dysfunction in
hepatic lipotoxicity A. Leamy, R.A. Egnatchik, M. Shiota, D.
Jacobson and J.D. Young. Vanderbilt Univ.
D305 1001.3 Alcohol potentiates HIV protease inhibitorinduced ER stress and hepatic lipotoxicity M. Hinton, R. Liu,
X. Zhang, X. Wang, W.M. Pandak, P.B. Hylemon and H.
Zhou. Virginia Commonwealth Univ., China Pharmaceut. Univ.
and McGuire VA Med. Ctr., Richmond.
D306 1001.4 Impact of DHA status on serum markers of
obesity and inflammation in pregnant women J.M. Chekal,
M. Harris and C.C. DiRusso. Univ. of Nebraska-Lincoln and
Colorado State Univ.
D307 1001.5 Cholesterol-depletion in human blood-derived
neutrophils by methyl-β-cyclodextrin leads to the formation of
neutrophil extracellular traps A. Neumann, G. Brogden, S.
Brodesser, H.Y. Naim and M. von Köckritz-Blickwede. Univ.
of Vet. Med. Hannover and Univ. of Cologne.
D308 1001.6 The host is a harsh mistress: role of fatty acid
synthesis in trypanosome survival K. Paul, C. McKnight and
S. Ray. Clemson Univ.
D309 1001.7 Steroids
contents
of
wound
healing
preparations from the skin of the Arabian Gulf catfish (Arius
bilineatus, Val.) J.M. Al-Hassan, S.O. George and M. Afzal.
Kuwait Univ.
D310 1001.8 The hypertriglyceridemic waist, waist-to-height
ratios and cardiometabolic risk in university students R.D.
Villalobos, D. Villalobos, M. Murguía-Romero, R. JiménezFlores, R. Méndez-Cruz, S. Sigrist-Flores, G. Medrano and
R. Villalobos-Molina. Monterrey Inst. of Technol. and Higher
Educ., Mexico City, UNAM, Tlalnepantla and Autonomous
Univ. of Ciudad Juárez, Mexico.
D311 1001.9 LC-MS/MS
determination
of
phosphatidylcholine hydroperoxide and its truncated products
in human blood plasma T. Miyazawa, S. Kato, K. Sawane, T.
Miyazawa and K. Nakagawa. Tohoku Univ.
D312 1001.10 Epigenetic regulation of LPS-induced lung
injury by sphingosine-1-phosphate lyase D.L. Ebenezer, Y.
Zhao, S.J. Ackerman and V. Natarajan. Univ. of Illinois at
Chicago.
1002.PROTEIN-LIPID INTERACTIONS
Poster
D313 1002.1 Decreased functionality of A164S variant of
apolipoprotein A-I in cardiovascular disease J. Petrlova, J.
Dalla-Riva and J. Lagerstedt. Lund Univ., Sweden.
D314 1002.2 Chimeric apolipoproteins as novel plasma
cholesterol lowering agents N.U. Ibe, M. Lek, W.H. Beck, P.M.
Weers and V. Narayanaswami. California State Univ., Long
Beach.
D315 1002.3 Identification and characterization of fatty acid
alkyl esterases found in Staphylococcus aureus B.D. Saylor
and J.J. Love. San Diego State Univ.
D316 1002.4 Apolipoproteins C-I and C-III inhibit lipoprotein
lipase activity by displacement of the enzyme from lipid
droplets M. Larsson, E. Vorrsjo, P. Talmud, A. Lookene and
G. Olivecrona. Med. Biosci., Umeå Univ., Ctr. for Cardiovasc.
Genet., London and Tallin Univ. of Technol., Estonia.
D317 1002.5 Fluorinated aromatic amino acids distinguish
side chain cation-π interactions from membrane insertion M.F.
Roberts, T. He and J. Gao. Boston Col.
D318 1002.6 The molecular mechanism of the Hsp70-lipid
interaction C. McCallister and N. Nikolaidis. California State
Univ., Fullerton.
1003.GLYCANS IN INJURY AND INFLAMMATION
Poster
D319 1003.1 Role of ICAM-1 hypoglycosylation in
atherosclerotic plaque formation M.O. Vallejo, D.W. Scott and
R.P. Patel. Univ. of Alabama at Birmingham and Univ. of North
Carolina at Chapel Hill.
D320 1003.2 ABO modulation of endothelial phenotypes
and glycome profile in human induced pluripotent stem cellderived endothelial cells H. Zhang, C. Mooney, M. Ishihara,
T. Kumagai, S. Stalnaker, S. Park, L. Veilion, C. Hinkle,
M. Stout, W. Yang, D. VanDorn, S. Chou, D.H. Bhang, S.
Ryeom, M. Tiemeyer, L. Wells, P. Azadi and M. Reilly. Univ.
of Pennsylvania, Univ. of Georgia and Children’s Hosp. of
Philadelphia.
323
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D321 1003.3 Intracellular hyaluronan protects murine
fibroblasts against apoptosis Y. Wang, M. Lauer, J. Mack and
E.V. Maytin. Cleveland Clin. Lerner Res. Inst., Dermatol. and
Plastic Surg. Inst., Cleveland Clin. and Dermat. and Plastic
Surg. Inst., Cleveland Clin.
D322 1003.4 Role of endothelial sialic acid expression
on xenogenic neutrophil adhesion B. French, D. Harris, P.
Benipal, R. Pierson and A. Azimzadeh. Univ. of Maryland
Baltimore.
D323 1003.5 Discovering a sialic acid independent ligand
for paired receptors Siglec-5 and -14 J. Fong, L. Deng, N.
Varki, V. Nizet and A. Varki. UCSD.
1004.GLYCANS IN VACCINE DEVELOPMENT AND
THE IMMUNE SYSTEM
Poster
D324 1004.1 N-glycan analysis of IgG by enzymatic
digestion with Remove-iT® Endo S and PNGase F E.A.
McLeod, C. McClung, A.M. Bielik, P.E. Magnelli and E.P.
Guthrie. New England Biolabs Inc., Ipswich, MA.
D325 1004.2 Human dendritic cells induce B-cell responses
to polysaccharide antigens D. Mendoza, Y. Xu, M. RodriguezBarradas, D.J. Tweardy, F.M. Orson and D.B. Corry. Baylor
Col. of Med. and VA Med. Ctr.
D326 1004.3 ArtinM activates CD4+ T cells through
recognition of N-glycans of CD3γ chain T.A. da Silva, M.A.
Souza and M.C. Roque Barreira. Univ. of São Paulo, Ribeirão
Preto.
D327 1004.4 Chemoenzymatic synthesis of HIV-1 V1V2
glycopeptide antigens for epitope characterization and
neutralizing antibody detection M.N. Amin, J.V. Lomino and
L-X. Wang. Univ. of Maryland Sch. of Med.
D329 1004.6 Investigating
the
role
of
protein
O-fucosyltransferase 1 in Toll-like receptor signaling J. Mann,
N. Li, K. Laky, I.D.C. Fraser and A. Nita-Lazar. NIAID, NIH.
D330 1004.7 The commensal glycoantigen PSA mitigates
inflammation through a novel mechanism of T cell-T cell
interaction M.B. Jones, J.L. Johnson and B.A. Cobb. Case
Western Reserve Univ.
1005.GLYCOBIOLOGY AND EXTRACELLULAR
MATRIX
Poster
D331 1005.1 The long non-coding RNA HAS2-AS1
enhances the transcription of hyaluronan synthase 2 D. Vigetti,
S. Deleonibus, M. Viola, E. Karousou, M.L. D’Angelo, G. De
Luca and A. Passi. Univ. of Insubria, Italy.
D332 1005.2 Reciprocal actions of Wnt9A and BMP4 on
chondroitin-4-sulfotransferase (CHST11) expression in relation
to arylsulfatase B activity S. Bhattacharyya, L. Feferman and
J. Tobacman. Univ. of Illinois at Chicago and Jesse Brown VA
Med. Ctr.
324
D333 1005.3 Binding of microfibril-associated glycoprotein
2 to extracellular microfibrils is promoted by proprotein
convertase cleavage B.L. Connett, E. Perez, L.J. Donovan,
G. Hogrebe, K. Lai, G. Withers and A. Miyamoto. California
State Univ., Fullerton.
D334 1005.4 Regulation of CCN2 and CCN3 in bone
marrow through myloid zinc finger-1 and its medical implication
in hematopoiesis A. Rozado, R. Piszczatowski, B. Rafferty
and N. Lents. John Jay Col., NY.
1006.GLYCOMICS
Poster
D335 1006.1 Glycoproteomics of the Zabrotes subfasciatus
larval midgut associated with the insecticidal mechanism of
the Olneya tesota PF2 lectin I. Lagarda-Díaz, A.M. GuzmánPartida, D.L. Geiser, J.J. Winzerling and L. VazquezMoreno. Ctr. for Food Res. and Develop. AC, Hermosillo,
Mexico and Univ. of Arizona.
1007.PROTEIN-GLYCAN FUNCTIONAL
INTERACTIONS
Poster
D336 1007.1 The role of VH CDR3 in determining Tn-antigen
specificities of MLS128 and 83D4 monoclonal antibodies H.
Sato. Tokai Univ. Sch. of Engin.
D337 1007.2 Mannose-based inhibitors of Escherichia coli
adhesion: design and applications J.M. Bouckaert. CNRS,
Villeneuve d’Ascq.
D338 1007.3 Characterization of an O-GlcNAc-binding
protein J. Groves and N. Zachara. Johns Hopkins Univ. Sch.
of Med.
D339 1007.4 Protein self-association of N-terminal domain
of β-1,3-glucan recognition protein upon binding to β-1,3glucan stimulates the prophenoloxidase activation in Manduca
sexta D. Takahashi, H. Dai, Y. Hiromasa, R. Krishnamoorthi
and M.R. Kanost. Kansas State Univ.
D340 1007.5 Specificity
of
glycosaminoglycan-protein
interactions: the role of desolvation A. Sarkar and U.R. Desai.
Virginia Commonwealth Univ.
D341 1007.6 Hyaluronan rafts in airway epithelial cells A.
Abbadi, M. Lauer, S. Swaidani and V. Hascall. Cleveland
Clin. Fndn.
D342 1007.7 Endo F3 glycosynthase mutant enables
chemoenzymatic synthesis of core fucosylated triantennary
complex type glycopeptides and glycoproteins J.P. Giddens,
J. Lomino and L-X. Wang. Univ. of Maryland Baltimore.
TUESDAYBIOCHEMISTRY
1008.STRUCTURAL DYNAMICS IN CELL SIGNALING
Poster
D343 1008.1 Deciphering the dynamic regulation of
phosphoinositide 3-kinases downstream of G-protein coupled
receptors and receptor tyrosine kinases J.E. Burke, O. Vadas,
O. Perisic and R.L. Williams. MRC Lab. of Molec. Biol.,
Cambridge.
1009.AGING
Poster
D344 1009.1 Dysregulated affinity of lamin A to SUN1
induces nuclear and endoplasmic reticulum aberrancies in
progeric laminopathies Y-H. Chi. Natl. Hlth. Res. Insts., Miaoli
Cty., Taiwan.
D345 1009.2 Life equations for the senescence process X.
Liu. The Ohio State Univ.
D346 1009.3 The improvement of neuronal function in
normal aging by melatonin is mediated by altering mitochondria
bioenergetics A.J. Idowu, I.I. Olatunji-Bello and Y. Bai. Lagos
State Univ. Col. of Med. and Univ. of Texas Hlth. Sci. Ctr.
D347 1009.4 Pulsed EPR distance measurements resolve
the impact of site-specific calmodulin methionine oxidation J.C.
Klein, M. McCarthy, M. Reuter, M. Olenek, R. Moen and D.
Thomas. Univ. of Wisconsin-La Crosse, Mankato State Univ.
and Univ. of Minnesota, Minneapolis.
D348 1009.5 Genome-wide microRNA and mRNA profiling
in skeletal muscle aging K-S. Kwon, J.Y. Kim, S-M. Lee, K.P.
Lee and S-Y. Kim. Korea Res Inst. Biosci. Biotech, Daejeon.
1010.APOPTOSIS AND CELL STRESS
Poster
D349 1010.1 Binge alcohol promotes acute liver injury
through a CYP2E1-HIF-1α-dependent apoptosis pathway in
mice and humans J-W. Yun, M-J. Son, M.A. Abdelmegeed,
A. Banerjee, T.R. Morgan, S-H. Yoo and B-J. Song. NIAAA,
NIH, Rockville, Seoul Natl. Univ. and VA Long Beach Healthcare
Syst.
D350 1010.2 IL-8 inhibits bortezomib-induced apoptosis in
ovarian cancer cells S.A. Phyo, B. Singha, H.R. Gatla and I.
Vancurova. St. John’s Univ.
D351 1010.3 Anti-apoptotic mechanism(s) of angiotensin
1-7/mas in alveolar epithelial cell survival I. Gopallawa and
B.D. Uhal. Michigan State Univ.
D352 1010.4 N-(1-pyrenyl)
maleimide
induces
Bak
oligomerization and mitochondrial dysfunction in Jurkat cells
T-C.V. Wang, P-R. Huang and C-C. Pao. Chang Gung Univ.,
Taiwan.
D353 1010.5 Static high-gradient magnetic fields affect the
functionality of monocytic cells T. Syrovets, Z. Schmidt, B.
Büchele, V. Zablotskii, A. Dejneka, N.M. Dempsey and T.
Simmet. Ulm Univ., Germany, Inst. of Phys., Acad. of Sci. of
Czech Republic and CNRS, UJF, Grenoble.
D354 1010.6 Hyperglycemia induces apoptotic signaling in
first trimester cytotrophoblast cells D. Leonard, D. Horvat,
M.R. Beeram, S.R. Allen, C.J. Meininger, D.C. Zawieja,
T.J. Kuehl and M.N. Uddin. Baylor Univ. and Scott & White
Healthcare/Texas A&M Hlth. Sci. Ctr. Col. of Med.
D355 1010.7 Effects of exposure to bisphenol A on
hepatocytes and pre-adipocytes in vitro E.A. Macis and T.Y.
Kostrominova. Indiana Univ. Sch. of Med.-Northwest.
D356 1010.8 Expression in yeast of the metacaspase scp3
from the fungus Schizophyllum commune A.R. Kaminski and
K.M. Fox. Union Col., NY.
D357 1010.9 Expression of the metacaspase cp3 from
the fungus Schizophyllum commune in Escherichia coli Z.T.
Spencer, C. Gagliardi and K.M. Fox. Union Col., NY.
D358 1010.10 Endoplasmic reticulum stress induces alveolar
epithelial cell apoptosis through the activation of the unfolded
protein response H. Nguyen, M. Dang, S. Ono, K. Morimoto
and B.D. Uhal. Michigan State Univ., Nagasaki Univ. Hosp.
and Nagasaki Univ.
D359 1010.11 UV irradiation/cold shock-induced NOS2
expression for causing nuclear bubbling is WWOX and p53
dependent N-S. Chang, S-J. Chen and P-W. Lin. Natl. Cheng
Kung Univ., Taiwan.
D360 1010.12 Effects of doxorubicin on the expression of
apoptotic-related genes in 22rv1 prostate cancer cells A.S.
Fong and B. Clack. Stephen F. Austin State Univ.
D361 1010.13 Functional analysis the role of the Kaposi
sarcoma-associated virus vBcl-2 protein in cellular apoptosis
E. Yasi, B. Caruso, S. Walker and J. Roecklein-Canfield.
Simmons Col.
D362 1010.14 Effects of microgravity on immune function:
benzofuran-2-carboxylic acid derivative as a countermeasure
A. Osborne, J. Agee, A. Scott, M. Shenwu, A. Sundaresan,
K. Marriott, S. Bhuiyan, R. Wilkins, B. Gersey, P. Denkins,
W. Williams and J. Mao. Tougaloo Col., MS, Texas Southern
Univ., Savanna State Univ., Jarvis Christian Col., TX, Prairie
View A&M Univ. and NASA/Johnson Space Ctr.
D363 1010.15 Synthesis and anti-microbial studies of a series
of 3-formylchromone thiosemicarbazone ligands and their
Cu(II) complexes including the potent Akt inhibitor [Cu(FCTSC)Cl2] A. Werlein and E. Lisic. Tennessee Tech Univ.
D364 1010.16 Cell survival proteins in fermented milk E.
Coria and M.M. Payne. Univ. of La Verne.
1011.CELL PROLIFERATION
Poster
D365 1011.1 Magnolol affects the expression of polyamine
biosynthesis and catabolism-linked proteins in PC3 human
prostate cancer cells in vitro B. McKeown and R. Hurta. Univ.
of Prince Edward Island, Canada.
D366 1011.2 Comparative heat shock response of wild yeast
isolated from spontaneous mezcal fermentation and controlled
laboratory yeast J.A. Mejía-Barajas, M. Arellano-Plaza and
A. Saavedra-Molina. Univ. Michoacana de San Nicolás de
Hidalgo, Mexico and CIATEJ, Guadalajara.
325
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D367 1011.3 Activation of the farnesoid X-receptor
suppresses cyclin D1 expression and decreases proliferation
G. Idelman, M.E. Vogel and S.D. Zucker. Univ. of Cincinnati.
D368 1011.4 Cellular effect of insulin on proliferation of
monocytes J. Naderi, A.J. Feuerherm, T.T.T. Nguyen and B.
Johansen. Norwegian Univ. of Sci. and Technol.
D369 1011.5 Chemopreventive effects of resveratrol
derivatives on breast cancer cells N. Campos, D. Costa and
J. Silva. Fed. Univ. of Rio de Janeiro.
D370 1011.6 Does newt blood regenerate via circulating
stem cells? G. Mele and S. Sessions. Hartwick Col., NY.
D371 1011.7 Angiotensin-II-induced expression of the early
growth response protein 1 is mediated by CaMKII-dependent
pathway in vascular smooth muscle cells E.R. Simo Cheyou
and A.K. Srivastava. Univ. of Montreal Hosp. Res. Ctr.
D372 1011.8 Basonuclin 2 overexpression promotes
keratinocyte proliferation and may contribute to basal cell
carinoma tumorigenesis B.J. Muller and J.C. Cornett. Lee
Univ., TN.
1012.CYTOKINE AND GROWTH FACTOR SIGNALING
Poster
D373 1012.1 Effects of tributyltin exposures on secretion of
interleukin 1 beta from human immune cells S. Brown and M.
Whalen. Tennessee State Univ.
D374 1012.2 Multiplex measurement of human kidney
biomarkers in serum using the Magnetic Luminex® Performance
Assay M. Anderson, M. Rynning, R. Fuerstenberg and J.
Schmidt. R&D Systs., Minneapolis.
D375 1012.3 Profiling 200 biomarkers in cancer cell culture
supernates and serum using Luminex® screening assays
J. David, M. Anderson, I. O’Brien, M. Schwartz and J.
Schmidt. R&D Systs., Minneapolis.
D376 1012.4 Effects of heparin and heparin-binding growth
factor on human aortic adventitial fibroblasts F. Kalle and R.E.
Akins. Univ. of Delaware and Nemours - Alfred I. duPont Hosp.
for Children.
D377 1012.5 Leucyl-tRNA synthetase is an amino acid
sensor for the activation of Vps34 upstream of mTORC1 M.S.
Yoon and J. Chen. Univ. of Illinois at Urbana-Champaign.
D378 1012.6 Antagonism of the prostaglandin E2 EP1
receptor in MDCK cells increases growth through activation
of Akt and the epidermal growth factor receptor M. Taub, P.
Mathivanan, R. Parker, T. Rudra and M.A. Ariff. Univ. at
Buffalo.
D379 1012.7 Insulin-like growth factor I regulation of FOXO1
in gonadotropes D.V. Skarra and V.G. Thackray. UCSD.
D380 1012.8 Y14 positively regulates TNF-α induced NFκB transcriptional activity via interacting RIP1 and TRADD
beyond an exon junction complex protein T. Matsuda, S. Togi,
S. Kon, Y. Sekine and R. Muromoto. Grad. Sch. Pharm.Sci.,
Hokkaido Univ.
326
1013.SECOND MESSENGERS
Poster
D381 1013.1 Soluble IP4 limits NK cell effector functions by
controlling PI3K signaling K. Sauer, E. Park, S. Siegemund,
A.R. French, J.A. Wahle, L. Sternberg, S. Rigaud, H.
Jonsson and W.M. Yokoyama. The Scripps Res. Inst. and
Washington Univ.
D382 1013.2 Plasma membrane recovery kinetics of a
microfluidic intracellular delivery platform R. Poceviciute, A.
Sharei, K. Jensen and R. Langer. Caltech and MIT.
D383 1013.3 Activation of Cdc42 is critical for sustained
Ca2+ oscillations stimulated by antigen crosslinking of IgE/
FcεRI complexes in RBL mast cells M.M. Wilkes, B. Baird and
D. Holowka. Cornell Univ.
D384 1013.4 DNA methyltransferase knockout alters calcium
homeostasis in HCT116 colon cancer cell line J. Rovatti, A.
Wu, S. Kinney and D.D. Bose. Western New England Univ.
Col. of Pharm.
D385 1013.5 NAADP evokes calcium signals and plays a
critical role in downstream physiological responses in naïve
T cells R.A. Ali, C. Camick, K. Wiles, J.T. Slama, D.R.
Giovannucci and K.A. Wall. Univ. of Toledo.
D386 1013.6 Microarray analysis of the effects of elevated
cAMP in differentiating osteoblasts K. Ghanayem, C. Cuppini
and R.P. Rylaarsdam. Benedictine Univ.
D387 1013.7 Direct PKA-PDE interactions lead to localized
cAMP signaling domains in adult cardiomyocytes B.W. Boras,
S. Taylor and A. McCulloch. UCSD.
D388 1013.8 Human p190A RhoGAP binds eIF3A and exists
in a complex with the 48S translational pre-initiation complex P.
Parasuraman, J.A. Walker, B. Li, P. Mulligan, W. Haas and
A. Bernards. Massachusetts Gen. Hosp. and Harvard Med.
Sch.
D389 1013.9 Structural and functional analyses confirm the
presence of functional P-loops and intrinsic GTPase activity in
Evc protein O. Odunuga. Stephen F. Austin State Univ.
D390 1013.10 Applying a chemical genetic approach to
inositol polyphosphate signaling J.K. Bratz, B.E. Dul and D.
Fiedler. Princeton Univ.
D391 1013.11 Reactivities of the sulphydryl groups of horse
(Equus caballus) haemoglobin O.E. Omotosho, C.N. Shalom,
T.V. Omotosho and K.O. Okonjo. Covenant Univ., Nigeria.
D392 1013.12 IP7K is kinetically well-equipped for cell
signaling but does not regulate CDK5 activity J.D. Weaver and
S.B. Shears. NIEHS, NIH, Research Triangle Park.
D393 1013.13 Insulin-stimulated neuronal nitric oxide
synthase phosphorylation is AKT2-dependent in C2C12
skeletal muscle cells K. Hinchee-Rodriguez, M.L. Adamo,
B.S. Masters and L.J. Roman. Univ. of Texas Hlth. Sci. Ctr. at
San Antonio.
D394 1013.14 Nucleotide regulation of soluble guanylate
cyclase N.B. Surmeli and M.A. Marletta. The Scripps Res.
Inst.
D395 1013.15 Analysis of the expression of eNOS in
erythrocytes under hypoxic conditions T.M. Nava Pérez, J.A.
Estrada, I. Contreras, B. Moreno-Altamirano and F.B.
Pliego-Rivero. Autonomous Univ. of Mexico State, Toluca and
Natl. Sch. of Biol. Sci., IPN, Mexico City.
TUESDAYBIOCHEMISTRY/NUTRITION
D396 1013.16 PP2A activation in vivo is sufficient to
disrupt interactions among vascular Akt-Hsp90-eNOS L.
Panneerseelan, T. Ruan, Y.Y. Li, X. Wan, D. Kunz, M.L.
Walker, J.K. Nhan, A. Ravindran, P.V.A. Babu, Q.J. Zhang,
E.D. Abel and J.D. Symons. Univ. of Utah and Univ. of Iowa.
D397 1013.17 Understanding how the distal pocket
environment affects the ligand binding affinity of nitrite to heme
proteins A.A. Garcia, R. Gomez, S. Wojdyla, L. Lough and
R. Esquerra. San Francisco State Univ.
D398 1013.18 Mechanistic insights into nitric oxide activation
of H-NOX sensor proteins M.A. Herzik, R. Jonnalagadda and
M.A. Marletta. Univ. of California, Berkeley and The Scripps
Res. Inst.
D399 1013.19 Phosphatidic acid activates mTORC1 by
displacing the inhibitor DEPTOR C. Plaisier, M.S. Yoon,
C. Wu, N. Truong and J. Chen. Univ. of Illinois at Urbana
Champaign.
D400 1013.20 Antitumor activity of sphingosine-1-phosphate
J. Yang, B. Ling, A. Sultan, D. Michel, H. Zhang, B.
Ma, J. Maley, R. Sammynaiken and J. Alcorn. Univ. of
Saskatchewan, Foshan Univ., China and Entry-Exit Inspect.
and Quarant. Bureau, Nanhai, China.
D401 1013.21 p54nrb/NONO regulates cAMP signaling and
cortisol production by modulating phosphodiesterase splicing
J. Yang and M.B. Sewer. UCSD.
D402 1013.22 Phosphodiesterase expression and cyclic diGMP production in Streptomyces coelicolor R.M. Geiger, J.T.
Tansey and J.A. Bennett. Otterbein Univ.
D403 1013.23 Phosphorylation regulates association of
PDE3A isoforms with distinct interactomes F. Vandeput, N.
Szabo-Fresnais, F. Ahmad, C. Kho, A. Lee, J. Krall, R.
Hajjar, V. Manganiello and M. Movsesian. Univ. of Utah,
NHLBI, NIH and Mount Sinai Sch. of Med.
Nutrition
1014.GLOBAL NUTRITION: FOOD SECURITY
Poster
(Sponsored by: Global Nutrition Council)
Presentation time: 12:45 pm–1:45 pm (I); 1:45 pm–2:45 pm (II)
C1
I
1014.1
Cultural
capital
associated
with
children’s food consumption and physical activity among
parents of first and second grade children in urban, suburban,
and rural Japan K. Goto, N. Fukushima, C. Wolff, M.
Giovanni and N. Murayama. California State Univ., Chico and
Niigata Prefect. Univ.
C2
II
1014.2
An empirical study on accountability for
promoting healthy food environments in England through the
Public Health Responsibility Deal Food Network V.I. Kraak,
B. Swinburn, M. Lawrence and P. Harrison. Deakin Univ.,
Australia.
C3
I
1014.3
Household food insecurity is associated
with childhood stunting in vulnerable populations in Lebanon
H. Ghattas, N.R. Sahyoun, A.J. Sassine, J.M. Barbour, K.
Seyfert, N. Hwalla and M. Nord. American Univ. of Beirut,
Univ. of Maryland College Park, Sch. of Oriental and African
Studies, London and USDA, Washington, DC.
C4
II
1014.4
Drug
susceptibility
influences
macronutrient intake and body composition in tuberculosis
patients J.K. Frediani, N. Tukvadze, E. Sanikidze, M. Kipiani,
G. Hebbar, V. Tangpricha, H.M. Blumberg and T.R. Ziegler.
Emory Univ., Emory Ctr. for Clin. and Molec. Nutr., Natl. Ctr. for
Tuberculosis and Lung Dis., Tbilisi, Georgia and Tuberculosis
and Lung Dis., Tbilisi, Georgia.
C5
I
1014.5
Food consumption of Indian adolescents
in a globalizing world N. Shaikh, S. Patil, U. Ramakrishnan
and S. Cunningham. Emory Univ. and Shri B.M. Patil Med.
Col., BLDE Univ., India.
C6
II
1014.6
Empowering adolescent girls against
anemia in West Bengal, India P. Chakraborty and I.
Bhattacharyya. SUNY Plattsburgh and Child in Need Inst.,
Kolkata.
C7
I
1014.7
Pregnancy
in
Mbale,
Uganda:
perceptions of food security and influences on women’s
breastfeeding intentions S.B. Ickes and L. Pugh. Col. of
William & Mary.
C8
II
1014.8
Parents
education
and
children
nutritional status aged 2 to 5 in Zambia H.A. Alalaq, S. Katuli,
L. Beeson, G. Ormsby and Z. Cordero-MacIntyre. Loma
Linda Univ. and Avondale Col., Australia.
C9
I
1014.9
A mixed-methods approach to construct
program-impact pathways and highlight the role of an
agricultural and market development program in supporting
household food security and dietary diversity among
smallholder farmers in Guatemala J.R. López Cintrón, R.D.
Peterson, P. Torres, A. Wuth, F.M. Dong, N.J. Engeseth, J.C.
Greene, W.G. Helferich and J.E. Andrade. Univ. of Illinois at
Urbana-Champaign and Univ. of Indianapolis.
C10 II
1014.10 2016: International year of pulse crops —
programming and potential impact on global nutrition research
funding J.M. Rueda. American Pulse Assn., Moscow, ID.
1015.GLOBAL NUTRITION: INFANT AND YOUNG
CHILD FEEDING
T
U
E
Poster
(Sponsored by: Global Nutrition Council)
C11
I
1015.1
Global trends in breastfeeding duration
M.C. Kay, M. Bentley and L. Adair. Univ. of North Carolina at
Chapel Hill.
C12 II
1015.2
Breast milk docosahexaenoic acid
levels from dried vs. liquid samples from mothers in Bangladesh
and Malawi K. Harris, E.Y. Jimenez, W. Petri, K.G. Dewey, P.
Ashorn, R. Haque, K. Maleta, C. Mangani and W.S. Harris.
OmegaQuant LLC, Sioux Falls, SD, Univ. of New Mexico,
Univ. of Virginia Med. Sch., Univ. of California, Davis, Univ.
of Tampere Sch. of Med., Finland, Intl. Ctr. for Diarrhoeal Dis.
Res., Dhaka, Bangladesh and Univ. of Malawi Col. Of Med.
327
NUTRITIONTUESDAY
C13 I
1015.3
Diversity of complementary feeding in
the first year of life differs by country: The Global Exploration of
Human Milk Study A.L. Morrow, P.M. Herbers, B.S. Davidson,
R.J. McMahon and J.G. Woo. Cincinnati Children’s Hosp.
Med. Ctr. and Mead Johnson Pediat. Nutr. Inst., Glenview, IL.
C14 II
1015.4
Breastfeeding practices as determinants
of nutritional status and growth of Bangladeshi infants prior to 6
months of age K.J. Schulze, R. Klemm, P. Christian, L. Wu,
A.A. Shamim, H. Ali, S. Shaikh, A. Labrique, S. Mehra and
K.P. West. Johns Hopkins Bloomberg Sch. of Publ. Hlth. and
JiVitA Proj., Gaibandha, Bangladesh.
C15 I
1015.5
Neonatal survival appears unaffected
by timing in the start of breast-feeding in rural Bangladesh R.D.
Klemm, L. Wu, P. Christian, A.A. Shamim, S. Shaikh, H. Ali,
S.D. Mehra, A.B. Labrique, K. Schulze and K.P. West. Johns
Hopkins Bloomberg Sch. of Publ. Hlth.
C16 II
1015.6
Breast milk correlates of immune
protection against early infancy Cryptosporidium infection in
a rural Tanzanian cohort S.H. Pedersen, A.L. Wilkinson, A.
Andreasen, S. Kinung’hi, D.C. Warhurst, M. Urassa, D.M.
Mkwashapi, J. Todd, J. Changalucha and J.M. McDermid.
Cornell Univ., London Sch. of Hyg. & Trop. Med. and Natl. Inst.
for Med. Res., Mwanza, Tanzania.
C17 I
1015.7
Analysis of hospital feeding practices at
Bach Mai Hospital, Hanoi Vietnam L.S. Young, P.T.T. Huong,
N.T. Lam, N.N. Thu, H.T. Van, D.T.K. Lien, T.H. Hoc, N.Q.
Anh, E.G. Henry, C.M. Lenders, K.M. Gura, C.M. Apovian
and T.R. Ziegler. Boston Univ., Natl. Insts. of Nutr., Hanoi,
Bach Mai Hosp., Hanoi, Boston Children’s Hosp. and Emory
Univ.
C18 II
1015.8
A village health worker-led intervention
to promote and support exclusive breastfeeding in rural
Zimbabwe is feasible, acceptable and effective C.R. Matare,
M.N. Mbuya, R.J. Stoltzfus, K.L. Dickin and J.H. Humphrey.
Zvitambo Res. Trust, Harare, Cornell Univ. and Johns Hopkins
Bloomberg Sch. of Publ. Hlth.
1016.LACTATION: DETERMINANTS OF
LACTOGENESIS, LACTATION DURATION AND
OTHER INDICATORS OF LACTATION SUCCESS
Poster
(Sponsored by: Lactation RIS)
C19 I
1016.1
The value of swabbing sore nipples
during lactation P.E. Hartmann, M. Rowan, E.S. Chia, K.A.
Fairclough, L.L. Menon, E. Ashton and J.C. Kent. Univ. of
Western Australia and King Edward Mem. Hosp. for Women,
Subiaco, Australia.
C20 II
1016.2
Factors influencing the decision to
formula feed infants N.E. Brown, M. Gregoire, D. Sowa, Y.
Chen and N. Ratz. Rush Univ. Med. Ctr.
C21 I
1016.3
Influences on decision to breastfeed
infants N. Coduti, M. Gregoire, D. Sowa, Y. Chen and G.
Diakakis. Rush Univ. Med. Ctr.
C22 II
1016.4
Determinants of exclusive breastfeeding
cessation in a peer counseling breastfeeding support program
for low-income women M. Rozga, P. Benton, J. Kerver and
B. Olson. Michigan State Univ., Michigan State Univ. Ext. and
Univ. of Wisconsin-Madison Ext.
328
C23 I
1016.5
Semi-automated detection of milk duct
dilatation recorded by ultrasound D. Geddes, J. Fiorentino
and A. Keating. Univ. of Western Australia.
C24 II
1016.6
Body
mass
index
influences
breastfeeding initiation and duration in a central Texas WIC
population H.E. Thornton, S.H. Crixell, J. Shumake, A.M.
Reat, J. Von Bank and B. Friedman. Texas State Univ. and
Univ. of Texas at Austin.
C25 I
1016.7
The effects of receiving supplemental
formula from WIC on a mother’s decision to discontinue
breastfeeding D. Watson, Y. Kim, J. Pope and H. McCollum.
Louisiana Tech Univ.
C26 II
1016.8
Breastfeeding intentions and practices
among the different vegetarian groups in the United States
A.M. Armstrong and A.K. Anderson. Univ. of Georgia.
C27 I
1016.9
The relation between breast milk
sodium to potassium ratio and maternal report of a milk supply
concern at 7 days postpartum M. Murase, E.A. Wagner, C.J.
Chantry, K.G. Dewey and L.A. Nommsen-Rivers. Cincinnati
Children’s Hosp. Med. Ctr., Univ. of California Davis Med. Ctr.
and Univ. of California, Davis.
1017.LACTATION: EFFECTS OF LACTATION/
BREASTFEEDING ON THE RECIPIENT INFANT
AND/OR LACTATING MOTHER
Poster
(Sponsored by: Lactation RIS)
C28 I
1017.1
Development of the enteric nervous
system and intestinal neuroendocrine systems in small for
gestational age and average for gestational age piglets during
the first month of life E.C. Radlowski, K. Le Boedec, X.
Zhang, R.N. Dilger, R.W. Johnson and S. Lezmi. Univ. of
Illinois, Urbana.
C29 II
1017.2
Breastfeeding during late pregnancy
did not affect infant breast milk consumption and growth R.G.
Pareja, G.S. Marquis and M.E. Penny. Nutr. Res. Inst., Lima,
Peru and McGill Univ.
C30 I
1017.3
Body composition of breastfed infants —
a comparison of bioelectrical impedance spectroscopy
and ultrasound assessment D.T. Geddes, Z. Gridneva, A.
Hepworth, C. Tat Lai and P. Hartmann. Univ. of Western
Australia.
C31 II
1017.4
Comparative
analysis
of
gut
microbiota of breast- and formula-fed Korean infants by using
pyrosequencing J.Y. Lim, S.A. Lee, M.N. Rhie, B-S. Kim,
S.J. Cho, O.B. Kim and Y. Kim. Ewha Womans Univ., South
Korea, Seoul Natl. Univ. and Ewha Womans Univ. Sch. of Med.
C32 I
1017.5
A comparison of bacterial communities
in feces of breastfed infants determined by 454 pyrosequencing
and Illumina MiSeq J.N. Mosely, J.E. Williams, K.M. Yahvah,
M.A. Riley, M.L. Settles, S.L. Brooker, K.A. Lackey, M.A.
McGuire and M.K. McGuire. Washington State Univ. and
Univ. of Idaho.
C33 II
1017.6
Breastfeeding
support
increases
breastfeeding duration among middle- to high-income women
A. Clark, S. Baker, K. McGirr, M. Harris and D. Davalos.
Univ. of Northern Colorado and Colorado State Univ.
TUESDAYNUTRITION
C34 I
1017.7
Maternal attitudes toward human milk
sharing E. O’Sullivan, S.R. Geraghty and K.M. Rasmussen.
Cornell Univ. and Cincinnati Children’s Ctr. for Breastfeeding
Med.
C35 II
1017.8
Aflatoxin M1 and ochratoxin A levels in
breast milk in Ankara, Turkey B. Barut Uyar, N. Karaağaoğlu,
G. Girgin, A. Gürbay and E. Karaağaoğlu. Gazi Univ. Fac. of
Hlth. Sci. and Hacettepe Univ. Fac. of Hlth. Sci., Turkey.
C36 I
1017.9
Lactation intensity and maternal
weight loss at two months postpartum in women with recent
gestational diabetes mellitus E.P. Gunderson, S.L. Matias
and K.G. Dewey. Kaiser Permanente Northern California and
Univ. of California, Davis.
C37 II
1017.10 Distribution of retinol, carotenoids
and tocopherols in serum lipoproteins in lactating women: a
longitudinal study A.G. Torres, M.R. Machado, D.I. Silva, J.C.
Nunes and F. Kamp. Fed. Univ. of Rio de Janeiro and Fed.
Inst. of Educ., Sci. and Technol., Rio de Janeiro.
C38 I
1017.11 Longer breastfeeding reduces the
positive relationships among gestational weight gain,
birthweight, and childhood growth Y. Zhu, L.M. Hernandez, Y.
Dong, J.H. Himes, S. Hirschfeld and M.R. Forman. Univ. of
Texas at Austin, Univ. of Minnesota, Minneapolis and NICHD,
NIH.
1018.DAIRY AND YOGURT: HEALTH AND NUTRITION
EFFECTS
Poster
C39 I
1018.1
Dairy consumption among American
children and adults: National Health and Nutrition Examination
Survey 1999-2008 H. Wang and P.F. Jacques. USDA at Tufts
Univ.
C40 II
1018.2
Yogurt consumption, socio-demographic
factors and lifestyle of the Italian population: results from the
INRAN-SCAI 2005-06 food consumption survey A. Turrini, L.
D’Addezio, L. Mistura and S. Sette. Agr. Res. Council – Res.
Ctr. for Food and Nutr., Rome.
C41 I
1018.3
Longitudinal association of dairy
consumption with changes in blood pressure and incident
hypertension H. Wang, L.M. Troy, C.S. Fox, J.B. Meigs, N.M.
McKeown and P. Jacques. USDA at Tufts Univ., Univ. of
Massachusetts Amherst, NHLBI Framingham Heart Study and
Massachusetts Gen. Hosp.
C42 II
1018.4
Association between dairy intake and
brain glutathione levels in older adults I-Y. Choi, P. Lee, D.R.
Denney, K. Spaeth, O. Nash, A.K. Roth, J.A. Lierman and
D.K. Sullivan. Univ. of Kansas Med. Ctr. and Univ. of Kansas.
C43 I
1018.5
Potential of glycated proteins produced
during aging of cheddar cheese to modulate fecal bacteria from
obese mice ex vivo and protect against colon inflammation J.
Yuan, K.S. Noratto, G.R. Munske, P. Pilla, I. Mohanty, D.E.
Alcantara Zapata and G.D. Noratto. Washington State Univ.
and Zamorano Pan-Am Agr. Sch., Honduras.
C44 II
1018.6
Yogurt intake is associated with a
healthier dietary pattern and is a lower contributor of energy
intake in obese individuals H. Cormier, E. Thifault, V. Garneau,
A. Tremblay, V. Drapeau, L. Perusse and M-C. Vohl. Inst. of
Nutr. and Funct. Foods, Quebec City and Laval Univ.
C45 I
1018.7
Longitudinal
association
between
yogurt consumption and the risk of overweight/obesity: the
SUN cohort study M.A. Martinez-Gonzalez, C. Sayon-Orea,
M. Ruiz-Canela, A. Gea, C. De la Fuente and M. BesRastrollo. Univ. of Navarra, Spain and CIBERobn, Madrid.
C46 II
1018.8
Positive association between fresh
dairy products consumption and healthy eating indexes in
french adults J-M. Lecerf, P. Hebel and J. Colin. Inst. Pasteur
Lille and CREDOC, Paris.
C47 I
1018.9
Dairy intake in the Mexican population:
2012 National Nutrition and Health Survey Results (ENSANUT
2012) N.P. Lopez, T.A. Aburto, L.S. Pedraza, T.G. Sánchez
and J.A. Rivera. Natl. Inst. of Publ. Hlth., Cuernavaca.
C48 II
1018.10 Clinical trials for foods: satiety panels J.
Kessler, M. Harris and J. Frestedt. Frestedt Inc., St. Louis
Park.
C49 I
1018.11 Yogurt consumption is associated with
lower body weight status and improved nutrient intakes in adult
women C.K. Gugger, N. Joshi and A.M. Albertson. General
Mills.
C50 II
1018.12 Effect of dairy foods vs. calcium and
vitamin-D supplements on bone metabolism: use of 41Ca
tracer E. Demmer, E.R. Gertz, T. Rogers, D. Hillgonds, M.
Garrod and M.D. Van Loan. Univ. of California, Davis, USDA,
Davis and Lawrence Livermore Natl. Lab.
1019.COMMUNITY AND PUBLIC HEALTH NUTRITION:
FOOD ENVIRONMENT AND FOOD SYSTEMS
Poster
(Sponsored by: Community and Public Health Nutrition
RIS)
C51 I
1019.1
The influence of community food
environment on weight status of young children participating in
the Children’s Healthy Living Program in Guam L. Matanane,
F. Li, R.T. Leon Guerrero, M. Acosta, R. Barber and M.K.
Fialkowski. Univ. of Hawaii at Manoa and Univ. of Guam.
C52 II
1019.2
Evaluating the effectiveness of a
nutrition-sensitive agriculture intervention in Western Kenya:
design of the Mama SASHA cohort study of vitamin A A. Webb
Girard, F. Grant, H. Okuku, V. Akelo, R. Wanjala, C. Levin,
D.C. Cole and J. Low. Rollins Sch. of Publ. Hlth., Emory Univ.,
Intl. Potato Ctr., Nairobi, Univ. of Washington and Dalla Lana
Sch. of Publ. Hlth., Univ. of Toronto.
C53 I
1019.3
Healthy kids, healthy Cuba: strategies
to increase healthy food access in an ethnically diverse, rural
Southwest community through policy and environmental
change P.C. Keane and A. Ortega. Univ. of New Mexico
Prevent. Res. Ctr.
C54 II
1019.4
The association between dietary intakes
and food environment factors H-Y. Paik, S. Lee, H. Jung and
Y-J. Song. Seoul Natl. Univ. and Catholic Univ. of Korea,
Bucheon.
C55 I
1019.5
Community
engagement
process
used to develop a food store intervention for a low-income
Brazilian urban area G.M. Vedovato, J. Gittelsohn, A.C.B.
Trude, M.R.T.F. Melzer, A.B.N. Santana, T.M. Furlani and
P.A. Martins. Fed. Univ. of São Paulo and Johns Hopkins
Bloomberg Sch. of Publ. Hlth.
329
T
U
E
NUTRITIONTUESDAY
C56 II
1019.6
Purchasing behaviors of individuals
who shop at corner stores T. Craven, A. Swanson, T. Young,
D. Martin and C. Gibson. Univ. of Kansas Med. Ctr. and MidAmerica Reg. Council, Kansas City, KS.
C57 I
1019.7
The Nutrition Environment Measurement
Survey-Stores in Guatemala: measurement performance
between the standard (USA) and a modified version R. Kanter,
J. Alvey, D. Fuentes, R. Garcia, R. Bearup, L. Koeppel, E.
Caplan, F. Chang, B. Chomitz and N.W. Solomons. INCAP
Comprehen. Ctr. for Prevent. of Chronic Dis. and CeSSIAM,
Guatemala City.
C58 II
1019.8
An evaluation of restaurants in
low-income communities using the Nutrition Environment
Measurement Survey for restaurants (NEMS-R) R.J. Leone,
K.R. Hemmingson, D.T. Remley, S. Zies, K. Kattelmann, Y.
Li and T. Kidd. The Ohio State Univ., South Dakota State Univ.
and Kansas State Univ.
C59 I
1019.9
Challenges
and
opportunities
associated with whole grains use in Twin Cities restaurants:
a food systems perspective A. Yangas, S. Berkowitz, M.
Riley, B. Maschoff, N. Schroeder and L. Marquart. Univ. of
Minnesota and Grains for Hlth. Fndn., St. Louis Park.
C60 II
1019.10 Factors influencing the use and
consumption of brown rice in Chinese restaurants T. Liu, X.
Wang and L. Marquart. Univ. of Minnesota.
C61 I
1019.11 Comparison
of
corresponding
commercially processed foods from store and restaurant for
sodium, fat, sugar and potassium content in a nationwide
sample J.K. Ahuja, P.R. Pehrsson, D. Haytowitz, B. Showell,
M. Nickle, S. Wasswa-Kintu and M. Cogswell. USDA,
Beltsville, MD and Ctrs. for Dis. Control and Prevent.
C62 II
1019.12 Of Soda and Sick Days: a field study of
firefighter diets K.M. Kniffin and B. Wansink. Cornell Univ.
C63 I
1019.13 Milk vending prevents the decline in
calcium intake in college students A.M. Rose, J.A. Kennel, A.
Wagner and C.W. Gunther. The Ohio State Univ.
C64 II
1019.14 Anti-diabetic efficacy of Fenfuro™,
a novel, patented Trigonella foenum-graecum seed extract
D. Bagchi, A. Swaroop, P. Kumar and M. Bagchi. Univ. of
Houston Col. of Pharm. and Cepham Inc., Piscataway.
C65 I
1019.15 The problem with low pricing: buffet
lunch and regret O. Sigirci and B. Wansink. Marmara Univ.,
Turkey and Cornell Univ.
C66 II
1019.16 Lower buffet prices lead to less taste
satisfaction D. Just, O. Sigirci and B. Wansink. Cornell Univ.
and Marmara Univ., Turkey.
C67 I
1019.17 Dynamics of dining in the groups of
people O. Sigirci and B. Wansink. Cornell Univ. and Marmara
Univ., Turkey.
C68 II
1019.18 Evaluation of the effectiveness of a
cafeteria-based behavioral economics intervention designed
to improve student intake of reimbursable meal components H.
Golub, C.W. Gunther and J.A. Kennel. The Ohio State Univ.
C69 I
1019.19 Behavioral economics and social
marketing campaign increases selection and consumption
of school lunch garden bar Items among elementary school
students J. Andre, C. Wolff, K. Goto, S. Bianco, M. Frigaard,
G. Hansen, R. Riley and S. St. Cin. California State Univ.,
Chico.
C70 II
1019.20 Family-style meals in a school
foodservice setting: a qualitative study J.E. Coborn, T.L.
Burgess-Champoux, R.A. Rosen and L. Marquart. Univ. of
Minnesota and St Catherine Univ.
330
C71 I
1019.21 Current practices and strategies to
improve the food environment in low-income schools to reduce
non-communicable risk factors in children in Guatemala City:
a qualitative study E.L. Pehlke, P. Letona and J. Gittelsohn.
Johns Hopkins Bloomberg Sch. of Publ. Hlth. and Inst. of Nutr.
of Central America and Panama, Guatemala City.
C72 II
1019.22 Children’s liking of child-friendly shaped
fruits and vegetables: does shape influence liking? S.L. Baker,
S.D. McCabe, S.E. Swithers, C.R. Payne and S. Kranz.
Purdue Univ. and New Mexico State Univ.
C73 I
1019.23 Adults’ attitudes toward and purchasing
intentions for child-friendly shaped healthy fruit and vegetable
snacks S.L. Baker, S.D. McCabe, S.E. Swithers, C.R. Payne
and S. Kranz. Purdue Univ. and New Mexico State Univ.
C74 II
1019.24 Development of child-friendly fish dishes
to increase young children’s acceptance and consumption
of fish L.R. Huss, S.D. McCabe, J.E. Dobbs-Oates, J.R.
Burgess, C.A. Behnke, C.R. Santerre and S. Kranz. Purdue
Univ.
C75 I
1019.25 Mothers’
dietary
behaviors
are
associated with nutritional status in their children S-H. Moon,
Y. Song and H.Y. Paik. Seoul Natl. Univ. and Catholic Univ. of
Korea.
C76 II
1019.26 Association between family structure
and food group intake in children Y.J. Baek, J.E. Shim and
H.Y. Paik. Seoul Natl. Univ. and Daejeon Univ.
C77 I
1019.27 Listeriosis: how concerned should a
pregnant woman be? L.A. Fahnestock, G. Gill, M. Randhawa,
S. Soret and N. Rizzo. Loma Linda Univ.
1020.NUTRITION EDUCATION AND TEACHING
Poster
C78 I
1020.1
Integrating nutrition throughout a
clinical presentation based medical education curriculum R.S.
Corniola and R. Suskind. California Northstate Univ.
C79 II
1020.2
Incorporating
nutrition
education
through applied, hands-on culinary elective in medical school
training K. Baker and M. Olfert. West Virginia Univ.
C80 I
1020.3
Nutrition education for medical students:
4th year transition to residency for primary care M.S. Edwards.
Univ. of Texas Med. Sch.
C81 II
1020.4
The use of technology in eating disorder
treatment programs J. Popelka, V. Quick, P. Murray and M.
Olfert. West Virginia Univ. and NICHD, NIH.
C82 II
1020.6
Consumer knowledge of non-nutritive
sweeteners C.J. Roemer, B.C. Ausenhus, A.T. Pientok, T.M.
Roelofs and T. Wilson. Winona State Univ.
C83 I
1020.7
Intensive use of primary literature in
science courses can supplement and prepare undergraduate
students for laboratory-based jobs and graduate programs B.
Varamini. Biola Univ., CA.
C84 II
1020.8
Methodology to evaluate changes in
eating and body-related attitudes, beliefs and behaviors among
female graduate students in dietetics C. Harris. Bastyr Univ.
TUESDAYNUTRITION
1021.NUTRITION EDUCATION: DEVELOPING
HEALTHY EATING AND PHYSICAL ACTIVITY
BEHAVIORS ACROSS THE LIFESPAN
1022.NUTRITION EPIDEMIOLOGY: INNOVATION
AND VALIDATION OF DIETARY ASSESSMENT
TOOLS AND THEIR APPLICATIONS
Poster
Poster
(Sponsored by: Nutrition Education RIS)
(Sponsored by: Nutrition Epidemiology RIS)
C85 I
1021.1
Barriers to physical activity experienced
by low-income mothers of young children: a pilot study H.
Desai. Rutgers Univ., Edison.
C86 II
1021.2
The role of ready-to-eat cereal in the
diets of children in the WIC Program: results from NHANES
2001-10 and USDA Food Patterns Equivalents Database A.M.
Albertson and N. Joshi. General Mills Inc., Minneapolis.
C87 I
1021.3
Using family-based experiential learning
to improve nutrition knowledge, dietary intake, physical activity,
and food purchasing behaviors among Latina WIC participants
and their children: a pilot study C. Gewa, L. Pawloski, A.
Kanianthra, M.M. Forrester, E.C. Long and M. Legum.
George Mason Univ., Fairfax County Hlth. Dept., Fairfax and
Fairfax County Hlth. Dept., Herndon.
C88 II
1021.4
The relationship between sociodemographic characteristics of South Mississippi adults to
reported fruit and vegetable intake and physical activity A.
Alakaam, D. Townsend, J.L. Lemacks and A.S. Landry.
Univ. of Southern Mississippi.
C89 I
1021.5
Effects of a health promotion program
for children on lifestyle and health indicators A.B. PerezLizaur, K. Haua - Navarro and L.I. Moreno-Landa. Univ.
Iberoamericana, Mexico City.
C90 II
1021.6
Physical
activity
behaviors
and
cognitions of parents of preschoolers K. Spaccarotella,
J. Martin-Biggers, N. Hongu, J. Worobey and C. ByrdBredbenner. Kean Univ.,Rutgers Univ. and Univ. of Arizona.
C91 I
1021.7
A mobile phone-based physical activity
recall using daily activity pictures: helping to recall intensity
and duration of physical activity B.T. Pope, P.J. Gallaway, U.
Flores, R.J. Turner and N. Hongu. Univ. of Arizona.
C92 II
1021.8
Diet quality among women participating
in the Pregnancy, Exercise, and Nutrition Feasibility Study
C. Graziano, J. Hansen, M. McLain, A. Horgan, E. Moe, L.
Goldberg and D. Stadler. Oregon Hlth. & Sci. Univ.
C93 I
1021.9
Predictors of physical activity selfefficacy change for rural-residing older adults S.L. Francis, A.
VanHauen, J. Margrett, M.C. Shelley and W.D. Franke. Iowa
State Univ.
C94 II
1021.10 Prevalence of orthorexia nervosa
among students at a rural university M. Neyman Morris, C.L.
Clark and K. Silliman. California State Univ., Chico.
C95 I
1021.11 Is eating breakfast associated with
increased fruit and whole grain intake in young women?
A.M. Widaman, E. Souza, S. Forester and N. Keim. Univ.
of California, Davis, Univ. of Califonria Davis Med. Ctr., Tahoe
Forest Hosp., Truckee, CA and USDA, Davis.
C96 II
1021.12 Impact of a point system program in
increasing fruit and vegetable consumption among university
employees N.V. Fernandes, S.C. Driver, R.R. Murr and C.A.
Friesen. Ball State Univ.
C97 I
1021.13 Health benefits of pear H. Reiland and
J. Slavin. Univ. of Minnesota.
C98 I
1022.1
Food
intake
reporting
among
adolescents using picture and text messaging with personal
mobile phones G.S. Siapco and J. Sabaté. Loma Linda Univ.
C99 II
1022.2
Development of a food preference
instrument for energy dense foods and sugar sweetened
beverages A.B. McGuerty, M.W. Cater, W. Prinyawiwatkul
and G. Tuuri. LSU and LSU AgCtr.
C100 I
1022.3
Food frequency questionnaire as an
indicator of serum essential n-3 and n-6 polyunsaturated fatty
acids concentrations in early pregnancy, according to body
mass index J. Lepsch, J. Vaz, T. Pinto, F. Rebelo, D. Farias,
A.B. Franco-Sena and G. Kac. Rio de Janeiro Fed. Univ.
C101 II
1022.4
Candy vs. snacks: parent and child
discussions of characteristics that define candy and snack
foods J.A. Bleser, B.Y. Rollins and L.L. Birch. Penn State,
State College and Penn State, University Park.
C102 I
1022.5
Seasonality in women’s dietary intake:
preliminary results from the Life in all Seasons study L. Jahns
and L.K. Johnson. USDA, Grand Forks.
C103 II
1022.6
Validity and reliability of food frequency
questions to assess beverages, fruits and vegetables, and
sweetened food intakes among 2- to 4-y-old WIC children
M. Koleilat, L. Jiang and S.E. Whaley. California State
Univ., Fullerton and Publ. Hlth. Fndn. Enterprises WIC Prog.,
Irwindale, CA.
C104 I
1022.7
Influence of editing free text responses
on nutrient and food group estimates from the Automated SelfAdministered 24-hour dietary recall (ASA24) N. Potischman,
T.P. Zimmerman, D. Douglass, S. Dixit-Joshi, S. Kirkpatrick,
A.F. Subar, S. McNutt, L.A. Coleman, G.L. Alexander, L.H.
Kushi and F.E. Thompson. NCI, NIH, Westat, Rockville, Univ.
of Waterloo, Canada, Abbott Nutr., Columbus, Henry Ford Hlth.
Systs. and Kaiser Permanente Northern California.
C105 II
1022.8
Development
of
non-invasive
assessments on vitamin A status by using skin levels of
carotenoids as biomarker – U.S. study M. Xiong and Y. Cai.
Max Nutr., Sandy, UT and Yale Univ. Sch. of Med.
C106 I
1022.9
Development
of
non-invasive
assessments on vitamin A status by using skin levels of
carotenoids as biomarker — India study M. Xiong, E.
Winterholler, M. Wipfel and D. Patel. Max Nutr., Sandy, UT
and Shaktikrupa Charitable Trust, Draper, UT.
C107 II
1022.10 My Plate visual mobile application
device for college students’ food intake tracking Y.M. Teo, T.
Pimentel, S.S. Wong, M. Cluskey, J. Dorbolo, M. Dinsmore
and R. Flynn. Oregon State Univ.
C108 I
1022.11 Assessment of diet and physical activity
of Brazilian schoolchildren: usability testing of a web-based
questionnaire P.F. Di Pietro, F.F. da Costa, C.P. Schmoelz,
V.F. Davies, E. Kupek and M.A.A. de Assis. Fed. Univ. of
Santa Catarina, Brazil.
331
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NUTRITIONTUESDAY
1023.NUTRITION EPIDEMIOLOGY: ADVANCING
NUTRITIONAL EPIDEMIOLOGY WITH PUBLIC
USE AND COMMERCIAL DATA SETS
Poster
C109 I
1023.1
Nutrient intakes among infants and
children from birth to 3 years M. Storey and P. Anderson.
Alliance for Potato Res. and Educ., McLean, VA.
C110 II
1023.2
Development of mercury database for
commonly consumed food among Koreans and assessment of
mercury exposure from diet among the Korean population S-A.
Kim, J.W. Lee, M. Jang, E. Lee and H. Joung. Grad. Sch.
of Publ. Hlth., Seoul Natl. Univ. and Inst. of Hlth. and Envrn.,
Seoul Natl. Univ..
C111 I
1023.3
Recent decreases in beverage calories
among U.S. preschoolers slowed by economic recession C.N.
Ford, S.W. Ng and B.M. Popkin. Univ. of North Carolina at
Chapel Hill.
C112 II
1023.4
Weekend intake is associated with
poorer diet quality, and increased intake energy and nutrients
to limit and poorer food choices in adults: National Health and
Nutrition Examination Survey 2001-2008 T.B. Ledet, C.E.
O’Neil, T.A. Nicklas and V.L. Fulgoni. LSU, LSU AgCtr.,
Baylor Col. of Med. and Nutr. Impact LLC, Battle Creek, MI.
C113 I
1023.5
Vegetable consumption and associated
nutrient intakes in the United States: results from NHANES
2009-10 and the new USDA Food Patterns Equivalents
Database C.K. Gugger, S. Bidwai, N. Joshi, N. Holschuh
and A.M. Albertson. General Mills.
1024.NUTRITION EPIDEMIOLOGY: ASSESSMENT
OF CHILD AND ADOLESCENT NUTRITIONAL
STATUS, GROWTH, AND OBESITY
Poster
C114 I
1024.1
Soy intake and age at onset of
menarche among adolescents with a high and wide range of
soy consumption J. Sabaté, G.S. Siapco, P. Pribis and K.
Oda. Loma Linda Univ. and Univ. of New Mexico.
C115 II
1024.2
Comparison of childhood cancer
survivors’ dietary intake with U.S. dietary guidelines F.F. Zhang,
E. Saltzman, A. Must, S. Liu, M.J. Kelly, S.K. Parsons and
S.B. Roberts. Tufts Univ., Boston, USDA at Tufts Univ. and
Tufts Med. Ctr.
C116 I
1024.3
Overweight and obesity of children in
Guam Y.C. Paulino, R.T. Leon Guerrero and J. Rosario. Univ.
of Guam Sch. of Nursing and Hlth. Sci., Univ. of Guam Col. of
Nat. and Applied Sci. and Guam Dept. of Educ., Hagatna.
C117 II
1024.4
Predictors of overweight or obesity in
school age children in Shanghai, China J. Xiong, A. Must, X.
Wang, Z. Gu, W. Xu and F. Zhang. Tufts Univ., Boston and
Zhabei District Ctr. for Dis. Control and Prevent., Shanghai.
332
C118 I
1024.5
Development of instructions and tape
measure to improve accuracy of parental report of preschool
height J. Martin-Biggers, M. Yorkin, C. Lozada, G.A.
Alleman, N. Hongu, J. Worobey and C. Byrd-Bredbenner.
Rutgers Univ. and Univ. of Arizona.
C119 II
1024.6
Anthropometric standardization in the
U.S. Affiliated Pacific: The Children’S Healthy Living Program
F. Li, L. Wilkens, R. Novotny, M. Fialkowski, Y. Paulino,
R. Nelson, A. Bersamin, U. Martin, R. Jim, J. Deenik
and C. Boushey. Univ. of Hawaii, Univ. of Guam, Northern
Marianas Col., Univ. of Alaska Fairbanks and American Samoa
Community Col.
C120 I
1024.7
Snacks contribute one third of nutrient
intake at three school levels in a population of Puerto Rican
children A.M. Preston, H. Venegas, N. Rodriguez, C.A.
Rodriguez and R.V. Rodriguez. Univ. of Puerto Rico.
C121 II
1024.8
The impact of nutritional status on
morbidities in mechanically ventilated critically ill children in
PICUs L.J. Bechard, C. Duggan, R. Touger-Decker, J.S.
Parrott, P. Rothpletz-Puglia, L. Byham-Gray, D. Heyland
and N.M. Mehta. Rutgers Sch. of Hlth. Related Professions,
Newark, Boston Children’s Hosp. and Queen’s Univ., Canada.
C122 I
1024.9
Dynamic effects of diet diversity and
breastfeeding on weight in months 6-24 of life M. Wright and
L.S. Adair. Univ. of North Carolina at Chapel Hill.
C123 II
1024.10 Prevalence of anemia and iron
deficiency among pregnant adolescents S. Lee, R. Guillet, E.
Cooper, M. Westerman, M. Orlando, E. Pressman and K.
O’Brien. Cornell Univ., Univ. of Rochester Sch. of Med. and
Dent. and Intrinsic Life Sci. LLC, La Jolla.
C124 I
1024.11 The association between nutritional
status and mortality in critically ill children admitted to the
pediatric intensive care unit L.J. Bechard, C. Duggan,
R. Touger-Decker, J.S. Parrott, P. Rothpletz-Puglia, L.
Byham-Gray, D. Heyland and N. Mehta. Boston Children’s
Hosp.,Rutgers Sch. of Hlth. Related Professions and Queen’s
Univ., Canada.
C125 II
1024.12 Comparison of food intake of vegetarian
and non-vegetarian adolescents N.M. Burkholder, G. Siapco,
S. Haddad Tabrizi and J. Sabate. Loma Linda Univ.
C126 I
1024.13 Micronutrient intakes among U.S.
children: understanding variability in different age and gender
groupings in NHANES 2007-2010 A.L. Eldridge, A. Rytz, K.
Van der Horst and V.L. Fulgoni. Nestle Res. Ctr., Lausanne
and Nutr. Impact LLC, Battle Creek, MI.
C127 II
1024.14 Rapid weight gain through age 4 y is
associated with increased adiposity, higher blood pressure and
insulin alterations at 4-5 y C.I. Ramírez-Silva, J.A. RiveraDommarco, B. Trejo-Valdivia, R. Martorell, A.D. Stein, U.
Ramakrishnan, I. Romieu and A. Barraza-Villarreal. Natl.
Inst. of Publ. Hlth., Cuernavaca, Emory Univ. and Intl. Agcy. for
Res. on Cancer, Lyon.
C128 I
1024.15 Comparison of food intake patterns
of adolescents with USDA My Plate Dietary Guidelines S.
Haddad Tabrizi, G. Segovia-Siapco, N. Medora Burkholder
and J. Sabaté. Loma Linda Univ.
C129 II
1024.16 The relationship between adolescent
pregnancy and adult height E.A. Lundeen, S. Norris, R.
Martorell, P.S. Suchdev, N. Mehta and A.D. Stein. Emory
Univ. and Univ. of the Witwatersrand.
C130 I
1024.17 Increasing insulin resistance among
U.S. adolescents ages 12-19: NHANES 2003-2010 D.L. Gee
and E.M. Davis. Central Washington Univ.
TUESDAYNUTRITION
C131 II
1024.18 Consumption
of
meat-containing
convenience foods may increase risk of obesity among
adolescents E.K. Bitok, A. Alabdrabalnabi, G. Siapco and J.
Sabaté. Loma Linda Univ.
C132 I
1024.19 Association between soy intake, infant
feeding type, and obesity risk in adolescents L. Huey, E. Bitok,
G. Siapco and J. Sabaté. Loma Linda Univ.
1025.AGING: NUTRITION INTERVENTIONS FOR RISK
FACTOR MODIFICATION IN CHRONIC DISEASE
Poster
(Sponsored by: Aging and Chronic Disease RIS)
C133 I
1025.1
Incidence of lactose intolerance in type
2 diabetic patients S.V. Rana, A. Malik, S. Bhadada and R.K.
Morya. Postgrad. Inst. of Med. Educ. and Res., Chandigarh,
India.
C134 II
1025.2
Consumption of low-fat dairy foods
for 6 months improves insulin resistance without adversely
affecting lipids or bodyweight in healthy adults T.C. Rideout,
C.P.F. Marinangeli and C.B. Rempel. Univ. at Buffalo and
Richardson Ctr. for Funct. Foods and Nutraceuts., Winnipeg.
C135 I
1025.3
Regular consumption of pulses does
not increase cerebrovascular vasodilator responsiveness A.M.
Hill, A.M. Coates, P.R. Howe and J.D. Buckley. Univ. of South
Australia and Univ. of Newcastle, Australia.
C136 II
1025.4
Diet, exercise, neurogenesis and
cognition T.E. Gibbons, B.D. Pence, T.K. Bhattacharya,
H.C. Mach, J.M. Ossyra, R.H. McCusker, K.W. Kelley, J.S.
Rhodes, R.W. Johnson and J.A. Woods. Univ. of Illinois at
Urbana-Champaign.
C137 I
1025.5
Dietary
supplementation
of
pomegranate reduces the brain oxidative stress in transgenic
tg2576 mouse model of Alzheimer disease S. Subash, M.M.
Essa, G.J. Guillemin, S. Al-Adawi, A. Al-Asmi and R.
Vaishnav. Sultan Qaboos Univ. Hosp., Muscat, Sultan Qaboos
Univ., Oman and Macqaurie Univ., Australia.
C138 II
1025.6
Tree nuts improve criteria of the
metabolic syndrome: a systematic review and meta-analysis of
randomized controlled dietary trials C.W. Kendall, S. Blanco
Mejia, E. Viguiliouk, L.S. Augustin, V. Ha, A. Cozma, A.
Mirahimi, A. Maroleanu, L. Chiavaroli, L.A. Leiter, R.J. de
Souza, D.J. Jenkins and J.L. Sievenpiper. Univ. of Toronto,
St. Michael’s Hosp., Univ. of Saskatchewan and McMaster
Univ., Canada.
C139 I
1025.7
Dietary and caloric restriction and agerelated spinal osteoarthritis: a longitudinal study of primates
J.F. Bailey, A.E. Duncan, R.J. Colman, J.A. Mattison and
P.A. Kramer. Univ. of Washington, Univ. of Wisconsin-Madison
and NIA, NIH, Baltimore.
C140 II
1025.8
Age-associated effect of freeze-dried
grape powder on inflammatory markers and physical activity
in adults with knee osteoarthritis R. Small, C. Tiernan, Y.H.
Kwon, R. Paulson, V. Imrhan, C. Prasad, P. Vijayagopal and
S. Juma. Texas Woman’s Univ.
C141 I
1025.9
The effects of freeze-dried mango on
bone parameters of ovariectomized mice H.F. Eldoumi, M.
Meister, S. Peterson, C. Ketz-Riley, P. Perkins-Veazie, C.L.
Stephen, B.J. Smith and E.A. Lucas. Oklahoma State Univ.
and North Carolina State Univ., Kannapolis.
C142 II
1025.10 Consumption of whole grape powder
reduces joint pain and influences serum biomarkers in
individuals with self-reported knee osteoarthritis C. Tiernan, R.
Small, Y-H. Kwon, R. Paulson, N. DiMarco, V. Imrhan, C.
Prasad, P. Vijayagopal and S. Juma. Texas Woman’s Univ.
C143 I
1025.11 Mass
spectrometry
quantitation
and analysis of urinary metabolites of grape seed extract
polyphenols in a rat model of menopause H. Kim, J.K. Cutts,
D.R. Moore and S. Barnes. Univ. of Alabama at Birmingham.
C144 II
1025.12 Lifestyle behaviors in early adulthood
may be important risk factors for age-related macular
degeneration M.J. Buck, M.M. Lewis, H.A. Durham, B.G.
Woods, C.L. Childress, A.V. Gaitan, M.L. Drewery, R.I.
Pinkston and C.J. Lammi-Keefe. LSU, Pennington Biomed.
Res. Ctr. and LSU AgCtr., Baton Rouge.
C145 I
1025.13 Butyrate increased lifespan in C.
elegans C. Gao, T. Cao, R. Martin, M. Keenan, F. Greenway,
J.W. Finley, J. Burton, W. Johnson, F. Enright and J. Zheng.
Sch. of Nutr. and Food Sci., LSU, Col. of Basic Sci., LSU, Univ.
of California, Davis, Pennington Biomed. Res. Ctr. and Sch. of
Animal Sci., LSU.
C146 II
1025.14 Gender effects of supplemental
amino acids on non-alcoholic fatty liver disease and chronic
inflammation L.M. Belalcazar, H. Spratt, M.C. Green, E.
Volpi, N. Hurren, R. Wolfe and E. Børsheim. Univ. of Texas
Med. Branch, Univ. of Colorado Denver, Aurora and Univ. of
Arkansas for Med. Sci.
C147 I
1025.15 Comprehension and use of Nutrition
Facts panels among young people in Canada E. Hobin, D.
Hammond, G. McVey, M. O’Brien and J. Sheeshka. Publ.
Hlth. Ontario, Toronto, Univ. of Waterloo, Hosp. for Sick
Children, Toronto and Victoria Univ., Australia.
C148 II
1025.16 Effect of tree nuts on glycemic control in
diabetes: a systematic review and meta-analysis of randomized
controlled dietary trials E. Viguiliouk, C.W. Kendall, S.B.
Mejia, A.I. Cozma, V. Ha, A. Mirrahimi, V.H. Jayalath, L.S.
Augustin, L. Chiavaroli, L.A. Leiter, R.J. de Souza, D.J.
Jenkins and J.L. Sievenpiper. Univ. of Toronto, St. Michael’s
Hosp., Toronto, Queen’s Univ. Sch. of Med. and McMaster
Univ., Canada.
C149 I
1025.17 Intake of trans fatty acid isomers found
in ruminant fat versus industrial sources differentially impact
concentrations of fatty acids in erythrocytes S.K. Gebauer,
N.R. Matthan, A.H. Lichtenstein and D.J. Baer. USDA,
Beltsville, MD and USDA at Tufts Univ.
C150 II
1025.18 Chronic date palm fruits supplementation
therapy reduces oxidative stress in transgenic (Tg2576)
mouse model of Alzheimer’s disease M.M. Essa, S. Subash,
K. Awlad-Thani, S. Al-Adawi, A. Al-Asmi, M. Samuoi, R.
Vaishnav and H. Al-Senawi. Macqaurie Univ., Australia,
Sultan Qaboos Univ., Oman, Sultan Qaboos Univ. Hosp.,
Muscat and Sultan Qaboos Univ.
333
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NUTRITIONTUESDAY
1026.AGING: NUTRITIONAL ASSESSMENT AND
STATUS IN OLDER POPULATIONS
1027.AGING: NUTRITION, PHYSICAL
PERFORMANCE AND BONE HEALTH
Poster
Poster
C151 I
1026.1
Actual issues of healthy nutrition in
dermatology A. Kalashnikova and E. Dalenov. Astana Med.
Univ., Kazakhstan.
C152 II
1026.2
Demographic determinants of body
mass index in healthy elderly men and women B. Azemati, S.
Rajaram, N. Kazzi, E. Bitok and J. Sabate. Loma Linda Univ.
Sch. of Publ. Hlth.
C153 I
1026.3
Determination of the size and weight
through the heel-knee length compared to direct measurement
in patients who use wheelchairs C. Torres Gomez, C.C.
Calzada Mendoza, A. Rivera-Llano, M.M. Granados-Diaz,
A. Sanchez-Sanchez, N. Onofre-Mendoza, R. MaldonadoTorres and C.A. Jimenez-Zamarripa. Ministry of Hlth., Valle
de Chalco, Mexico, Sch. of Med., Natl. Polytech. Inst., Mexico
City and Interdisc. Ctr. for Hlth. Sci., IPN, Mexico City.
C154 II
1026.4
Health status of a low socioeconomic
elderly population that participates in a community senior meal
program H.L. Tsunoda, J.W. Min, M. Piwowarski and M.Y.
Hong. San Diego State Univ. and Sr. Community Ctr. of San
Diego.
C155 I
1026.5
Nutritional vulnerability of older adults
living with their families in urban areas of Ankara, Turkey: a
cross-sectional study N. Yabanci, P. Bilgic, I. Simsek, M.
Tayfur and N. Hongu. Ankara Univ., Hacettepe Univ., Gazi
Univ., Baskent Univ., Turkey and Univ. of Arizona.
C156 II
1026.6
Dietary
intake
frequencies
and
nutritional risk in community-residing older adults S.L. Francis
and L.R. MacNab. Iowa State Univ.
C157 I
1026.7
Diet quality in community dwelling
obese women following a behavioral-based diet, tai chi, and
resistance training intervention A. Taetzsch, D. Lobuono, D.
Quintanilla, S. Maris, J. Letendre, A. Picard, L. Mahler, F.
Xu, M.J. Delmonico and I.E. Lofgren. Univ. of Rhode Island.
C158 II
1026.8
Factors related to improvement and
decline in high and low nutritional risk community-dwelling
Canadian older men: The Manitoba Follow-up Study (MFUS)
C.O. Lengyel, E.C. Harms and R.B. Tate. Univ. of Manitoba.
C159 I
1026.9
Muscle quality and metabolomics
analysis of young and old subjects B.A. Watkins, J. Kim, M.S.
Fragala, M.E. Carlson, A.M. Kenny, K.L. Pappan and G.A.
Kuchel. Univ. of Connecticut, Farmington, Univ. of Central
Florida and Metabolon Inc., Durham, NC.
C160 II
1026.10 Hand-held
ultrasound
device
demonstrates poor reliability for assessing and tracking muscle
mass in older adults M. Tian, J.S. Oliver, V.A. Mustad and
J.R. Stout. Abbott Nutr. and Univ. of Central Florida.
C161 I
1027.1
Adiponectin receptor 1 mediates
regulation of bone formation and osteoblast differentiation by
GSK-3β/β-catenin signaling Y.Y. Lin, C.Y. Chen, S.C. Wu, H.J.
Mersmann and S.T. Ding. Natl. Taiwan Univ. and Baylor Col.
of Med./Florida.
C162 II
1027.2
Impact of exercise and/or betaalanine and epigallocatechin gallate on muscle function and
oxidative stress in aged mice B.D. Pence, T.E. Gibbons, T.K.
Bhattacharya, H.C. Mach, J.M. Ossyra, R.H. McCusker,
K.W. Kelley, J.S. Rhodes, R.W. Johnson and J.A. Woods.
Univ. of Illinois at Urbana-Champaign.
C163 I
1027.3
Effects of defatted dried bonito fish on
bone mass, bone composition, and bone strength in Wistar
and Goto-Kakizaki rats M. Ochiai, S. Gohtani and T. Matsuo.
Kagawa Univ. Fac. of Agr., Japan.
C164 II
1027.4
Analysis of BMI, blood pressure,
cholesterol, BMD and nutrient intake with different age of adult
women in Korea J.O. Koo and M.S. Kim. Korea Natl. Open
Univ.
C165 I
1027.5
The effectivness of daily consumption
of 50 g dried plum on improving indices of bone turnover in
osteopenic postmenopausal women D. Metti, D. Ortiz, A.
Cravinho, Y. Vereda, S. Garcia, Z. Clayton, M. Kern, B.H.
Arjmandi and S. Hooshmand. San Diego State Univ. and
Florida State Univ.
C166 II
1027.6
Soda consumption and the risk
of hip fractures in postmenopausal women T. Fung, M.
Arasaratnam, F. Grodstein, J. Katz, B. Rosner, W. Willett
and D. Feskanich. Simmons Col., Univ. of North Carolina at
Chapel Hill, Channing Div. of Network Med., Boston, Brigham
and Women’s Hosp. and Harvard Sch. of Publ. Hlth.
C167 I
1027.7
Black currant extract attenuates
ovariectomy-induced bone loss in mice X. Zheng, S. Mun,
S.G. Lee, T. Vance, P. Hubert, S.I. Koo, S.K. Lee and O.K.
Chun. Univ. of Connecticut and Univ. of Connecticut Hlth. Ctr.
C168 II
1027.8
Infant formula increases bone turnover
favoring bone formation J-R. Chen, A. Andres, O.P. Lazarenko,
M.J.J. Ronis and T.M. Badger. Arkansas Children’s Nutr. Ctr.
C169 I
1027.9
Effect of chronic mushroom intake on
functional fitness in older men and women B.T. Williams, H.R.
Marsales, A.E. Millen, H.W. Burton, R.W. Browne and P.J.
Horvath. Univ. at Buffalo.
334
TUESDAYNUTRITION
1028.OBESITY: PHYSICAL ACTIVITY
Poster
(Sponsored by: Obesity RIS)
C170 I
1028.1
Effects of a short-term heavy resistance
training in young and older adults for strength and body
composition G.J. Cloutier, D. Forman, N. Lindegger, R.
Roubenoff and C. Castaneda-Sceppa. Northeastern Univ.
Col. of Hlth. Sci., Brigham and Women’s Hosp., Novartis Insts.
for Biomed. Res., Basel and Novartis Insts. for Biomed. Res.,
Cambridge, MA.
C171 II
1028.2
Plasma fetuin-A and phosphofetuin-A
(Ser312) responses to a single or short-term repeated bout of
exercise in obese and normal-weight individuals S. Mathews,
G. Ren, X. He, R.L. Bowers, F. Araya-Ramirez, L.A.
Littlefield and P.W. Grandjean. Auburn Univ., Auburn Univ.
Sch. of Kinesiol. and Baylor Univ.
C172 I
1028.3
Low intrinsic aerobic fitness increases
susceptibility to OVX-induced obesity and insulin resistance
in the absence of adipose tissue inflammation R. Welly, J.
Padilla, Y-M. Park, R. Scroggins, S. Britton, L. Koch, M.
Margo, N. Jenkins, J. Thyfault and V.J. Vieira-Potter. Univ.
of Missouri-Columbia, Univ. of Michigan Med. Sch. and Univ. of
Georgia.
C173 II
1028.4
Cardiorespiratory fitness levels among
U.S. adolescents J.J. Gahche, T.H. Fakhouri, J.E. Fulton,
D.D. Carroll, C-Y. Wang and V.L. Burt. Natl. Ctr. for Hlth.
Stats., Hyattsville, MD and Ctrs. for Dis. Control and Prevent.
C174 I
1028.5
Trend and features of top 100 grossing
health and fitness iPhone apps Y. Meng and S.S. Wong.
Oregon State Univ.
C175 II
1028.6
Effects of aerobic or resistance exercise
training in the management of genetic predisposition to obesity
M. Sartori, F. Santos, K. De Angelis and M.C. Irigoyen. Med.
Sch. of São Paulo Univ. and Nove de Julho Univ., São Paulo.
C176 I
1028.7
Impact of an integral health program
for metabolic diseases M. Vergara-Jimenez, S. Ochoa, A.
Ochoa, J.A. Magaña, A. Lugo-Vega and J.M. Cardenas.
Autonomous Univ. of Sinaloa, LAB-Clin. Labs., Culican and
Res., Sci. and Technol. Intl., SA de CV, Mexico City.
1029.OBESITY: CHRONIC DISEASES
Poster
C177 I
1029.1
High refined carbohydrates diet
promotes comparable hepatic tumorigenesis in mice as high
fat diet, potentially through inducing endoplasmic reticulum
stress PKR-like kinase signaling B.C. IP, C. Liu, D.E. Smith
and X-D. Wang. USDA at Tufts Univ. and Friedman Sch. of
Nutr. Sci. and Policy, Tufts Univ.
C178 II
1029.2
Unfolded protein response on renal
lipogenesis in C57BL/6 mice C. Tovar-Palacio, I. TorreVillalvazo, G. Alemán, E. Figueroa-Juárez, N. Torres, A.R.
Tovar and R. Correa-Rotter. Salvador Zubirán Natl. Inst. of
Med. Sci. and Nutr., Mexico City.
C179 I
1029.3
High vitamin D and calcium intakes
increase bone mineral content in diet-induced obesity Q. Song
and I.N. Sergeev. South Dakota State Univ.
C180 II
1029.4
Relationship of triglyceride levels with
A1C and adiponectin in Haitian Americans with type 2 diabetes
J. Antwi, A. Cheema, S. Ajabshir, J. Exebio, G.G. Zarini, J.
Vaccaro and F.G. Huffman. Florida Intl. Univ.
C181 I
1029.5
Association between ghrelin and
triglyceride levels in Blacks with and without type 2 diabetes
F.G. Huffman, T. Frade, M. Mclean, G.G. Zarini, J. Exebio, J.
Antwi, S. Ajabshir and J. Vaccaro. Florida Intl. Univ.
C182 II
1029.6
Abnormal
pulse
pressure
and
microalbuminuria in Haitian Americans with type 2 diabetes
G.G. Zarini, J. Vaccaro, S. Ajabshir, J. Antwi, A. Cheema
and F.G. Huffman. Florida Intl. Univ.
C183 I
1029.7
Body mass index and serum vitamin D
levels in Cuban, African, and Haitian Americans with type 2
diabetes F.G. Huffman, K. Feijao, L.H. Shaban, G.G. Zarini,
S. Ajabshir and J.A. Vaccaro. Florida Intl. Univ. and Kuwait
Univ. Col. for Women.
C184 II
1029.8
Imidacloprid decreased lifespan and
increased intestinal fat deposition in C. elegans J. Zheng,
H. Sirigireddy, C. Gao, F.L. Greenway, R.J. Martin, M.J.
Keenan, J. Burton, W.D. Johnson, J.W. Finley, F.M. Enright,
P. Shen and Y. Park. Pennington Biomed. Res. Ctr., LSU, Baton
Rouge, Univ. of California, Davis and Univ. of Massachusetts
Amherst.
1030.OBESITY: INSULIN RESISTANCE
Poster
C185 I
1030.1
Impaired insulin-mediated vasodilation
may contribute to hyperglycemia following high fat intake
K. Ricklefs, A. Simperova, P. Reaven, M. Sands and K.
Sweazea. Arizona State Univ. and Carl T. Hayden VA Med. Ctr.
C186 II
1030.2
Resistant starch improves insulin
resistance and reduces adipose tissue weight and CD11c
expression in the adipose tissues of OLETF rats T. Goda,
T. Harazaki, S. Inoue, C. Imai and K. Mochizuki. Univ. of
Shizuoka and Univ. of Yamanashi.
C187 I
1030.3
Association between serum vitamin D
and insulin resistance in African Americans with type 2 diabetes
J. Exebio, G.G. Zarini, J. Vaccaro, S. Ajabshir, A. Cheema,
J. Antwi, J. Antwi and F.G. Huffman. Florida Intl. Univ.
C188 II
1030.4
Interaction of dietary iron and fat on
glucose clearance A.L. Byrd, L. Liu, W. Cao, K. Erikson
and J. Han. North Carolina A&T State Univ., Univ. of North
Carolina at Chapel Hill, Kannapolis and Univ. of North Carolina
at Greensboro.
C189 I
1030.5
Supplementation with vitamin E and
vitamin C inversely alters mitochondrial copy number and
mitochondrial protein in obese, exercising rats M.J. Picklo.
USDA, Grand Forks.
335
T
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NUTRITIONTUESDAY
1031.OBESITY: BODY COMPOSITION
Poster
C190 I
1031.1
Effects of onion peel extract on body
composition changes in overweight Korean adults J-E. Yim,
R. Choue, Y-S. Kim, K-H. Lee and Y-J. Cha. Changwon Natl.
Univ., Kyung Hee Univ. and Kyung Hee Med. Ctr., South Korea.
C191 II
1031.2
Prediction of pre-pregnancy weight from
first trimester visit D.M. Thomas, M.W. Halawani, S. Phelan,
N.F. Butte and L.M. Redman. Montclair State Univ., California
Polytech State Univ., San Luis Obispo, Baylor Col. of Med. and
Pennington Biomed. Res. Ctr., Baton Rouge.
C192 I
1031.3
A 12-country assessment of body
adiposity in Latin American children and its association
with cardiometabolic risk factors F. Vasta, C. Slater and B.
Caballero. Johns Hopkins Univ. and Intl. Atomic Energy Agcy.,
Vienna.
C193 II
1031.4
Lentils counteract the ability of dietary
fat to increase adiposity in growing C57BL/6J female mice D.L.
Hadsell, S. Loewus, W. Olea, L.A. Hadsell and M.A. Grusak.
Baylor Col. of Med.
C194 I
1031.5
Age-related differences in select
systemic and local biomarkers affecting body composition in
ovariectomized rats Z. Ezzat-Zadeh, P.B. Chase, J-S. Kim
and B.H. Arjmandi. Florida State Univ.
C195 II
1031.6
Body composition changes within the
first four weeks of the freshman year at a private university
L.G. Meeks, D.L. Vera and S.L. Dunn. Univ. of La Verne.
C196 I
1031.9
Concordance
of
self-report
and
measured height and weight of college students C. ByrdBredbenner, V. Quick, A.A. White, S. Shoff, B. Lohse,
T. Horacek, K. Kattlemann, B. Phillips, S. Hoerr and G.
Greene. Rutgers Univ., NICHD, NIH, Univ. of Maine, Univ.
of Wisconsin-Madison, Penn State, Syracuse Univ., South
Dakota State Univ., Tuskegee Univ., Michigan State Univ. and
Univ. of Rhode Island.
C197 II
1031.10 Regional fat pattern differences between
8-11, 12-15, and 16-19 year-old male and female children R.T.
Davidson and W. Corbin. Logan Univ., MO.
C198 I
1031.11 Health risk indicators in incoming
freshmen at a public mid-western university R.J. Leone, M-J.
Ludy and A. Morgan. Bowling Green State Univ.
C199 II
1031.12 Evaluation of body composition by two
current bioelectric impedance small scales as compared with
two new anthropometric equations and the two most published
used equations used as references P. Masse, R. Jerbi, M-P.
Laforge and M. Pacifique. Univ. of Moncton, Canada.
C200 I
1031.13 Comparison of body composition and
body mass index on health status indicators K. Julander and
R. Litchfield. Iowa State Univ.
C201 II
1031.14 Proportionality of regional fat pattern
changes with weight change R.T. Davidson and G. Gibson.
Logan Univ.
C202 I
1031.15 The
relationship
between
body
composition, disease activity, and functional status in adults
with rheumatoid arthritis K. Woolf, M. Kiely and Y. Yazici.
NYU and NYU Langone Med. Ctr.
336
C203 II
1031.16 A case study of the influence of maternal
pregnancy body composition changes on newborn outcomes
A.J. Weekley, K.R. Harper, C.N. Bailey and A.K. Anderson.
Univ. of Georgia.
C204 I
1031.17 Urbanization effect on pre- vs. postnatal
mis-matched young child growth in China J. Min and Y. Wang.
Korea Inst. of Child Care and Educ., Seoul and Univ. at Buffalo,
SUNY.
1032.ANIMAL RESEARCH MODELS IN NUTRITION
AND MUSCULOSKELETAL DEVELOPMENT
Poster
(Sponsored by: Experimental Animal Nutrition RIS)
C205 I
1032.1
Green tea polyphenols improve cortical
bone and bone quality in alcohol-induced bone loss of young
male rats C.L. Shen, S.L. Bergeson, P. Syapin, G. Brackee,
J.L. Graef and B.J. Smith. Texas Tech Univ. Hlth. Sci. Ctr. and
Oklahoma State Univ.
C206 I
1032.2
Cannabinoid receptor expression in
femora and tibiae of C57/blk6 mice fed DHA and relationship to
bone ash and BMC J. Kim, K.L. Insogna and B.A. Watkins.
Univ. of Connecticut, Farmington and Yale Univ.
C207 I
1032.3
Expression of insulin-like growth factor
family members in myostatin null mice D.L. Clark, D.I. Clark,
E.K. Hogan, K.A. Kroscher and A.C. Dilger. Univ. of Illinois at
Urbana-Champaign.
C208 II
1032.4
Expression of growth regulatory genes
in skeletal muscle of myostatin null mice K.A. Kroscher, D.L.
Clark and A.C. Dilger. Univ. of Illinois at Urbana-Champaign.
1033.ANIMAL RESEARCH MODELS OF FETAL
PROGRAMMING
Poster
(Sponsored by: Experimental Animal Nutrition RIS)
C209 II
1033.1
Effect of vitamin K2 on trabecular bone
mass in senescence-accelerated mice P6 with water-immersion
restraint stress H. Katsuyama, S. Fushimi, K. Yamane, M.
Tomita, Y. Watanabe, T. Okuyama, M. Katsuyama, S.R.
Rahayu and K. Saijoh. Kawasaki Med. Sch. and Kanazawa
Univ., Japan.
C210 II
1033.2
Heat stress during differentiation of
porcine adipocytes is accompanied by increased expression of
adipocyte marker genes and downregulation of inflammatory
genes H. Lu, H. Wang and K.M. Ajuwon. Purdue Univ.
C211 I
1033.4
Effect of the porcine IGF2 intron3
G3072A substitution on development and growth of skeletal
muscle D.L. Clark, D.I. Clark, J.E. Beever and A.C. Dilger.
Univ. of Illinois at Urbana-Champaign.
C212 II
1033.5
Analysis of the differentiation capacity
of muscle satellite cells derived from FOXO1- genetically
modified mice A. Yamashita, Y. Hatazawa, R. Yoshimura,
S. Ogawa, Y. Ono and Y. Kamei. Kyoto Prefect. Univ. and
Nagasaki Univ.
TUESDAYNUTRITION
C214 I
1033.7
Maternal high fat feeding alters bone
lipid content at weaning without long-lasting effects on bone
lipid content and bone strength in male offspring at young
adulthood P.M. Miotto, L.M. Castelli, P.J. LeBlanc, S.J.
Peters, B.D. Roy and W.E. Ward. Brock Univ., Canada.
C213 II
1033.6
Organ inflammation and oxidative
damages in fructose-fed adult offspring born of fructose-fed
dams: modulation by maternal bitter melon supplementation
E.T.S. Li and R.H.H. Ching. Univ. of Hong Kong.
C215 I
1033.8
Effects of methylating vitamins and
docosahexaenoic acid supplementation on intra-uterine
growth retardation in a feed-restricted swine model H. Lima,
S. Jacobi, C. Man, K. Walker, J. Sommer, W. Flowers, A.
Blikslager, L. Xi and J. Odle. North Carolina State Univ.
C216 II
1033.9
In utero exposure to dietary lipotropes
affects DNA methylation and gene expression in mammary
glands of offspring K.B. Cho, L. Mabasa, K. Cho, C.L. Crane,
W-S. Choi and C. Park. North Dakota State Univ.
C217 I
1033.10 Sirt1 nutrient signaling regulates fetal
programming of nephrogenesis T.R. Magee, C.R. Nast, M.G.
Ross and M. Desai. David Geffen Sch. of Med. at UCLA,
Harbor-UCLA Med. Ctr., Charles R. Drew Univ. of Med. and
Sci. and Cedars-Sinai Med. Ctr.
C218 II
1033.11 Early sex differences in hepatic
metabolic signaling in offspring of obese female mice C.N.
Miller, S. Krishna, Z. Lin, M.A. Della-Fera, D.A. Harn, C. de
la Serre, C.A. Baile and N.M. Filipov. Univ. of Georgia.
1034.MEDICAL NUTRITION: NUTRITION AND
INFLAMMATION
Poster
(Sponsored by: Medical Nutrition Council)
C219 I
1034.1
The role of hepcidin in the pathogenesis
of anemia in Zimbabwean infants T.G. Mupfudze, R.J.
Stoltzfus, S. Rukobo, L.H. Moulton, J.H. Humprey and A.J.
Prendergast. Johns Hopkins Sch. of Publ. Hlth., Zvitambo
Inst. for Maternal Child Hlth. Res., Zimbabwe, Cornell Univ.
and Queen Mary Univ. of London.
C220 II
1034.2
Phenylketonuria is a condition of
inflammation associated with high BMI and low bone turnover
K.E. Coakley, T.D. Douglas and R.H. Singh. Emory Univ.,
Decatur.
C221 I
1034.3
Red ginseng supplementation effects
on the liver inflammation in whole-body gamma irradiated mice
E-H. Sohn, S. Namkoong, S-A. Jang, T-H. Kim, S.C. Kang
and H.J. Koo. Kangwon Natl. Univ. and Gachon Univ., South
Korea.
C222 II
1034.4
Eating behavior and its association
with measures of adiposity and metabolic risk factors in
women - Brazilian Metabolic Syndrome Study (BRAMS) R.S.L.
Cassani, A.L.G. Freitas, O.S. Amâncio, J.C. Pareja and B.
Gelonze. Fac. of Med. of Ribeirão Preto, Univ. of São Paulo
and UNICAMP, Brazil.
C223 I
1034.5
Longitudinal changes in the dietary
inflammatory index: an assessment of the inflammatory
potential of diet over time in the Women’s Health Initiative
F.K. Tabung, S.E. Steck, J. Zhang, A.D. Liese, Y. Ma, J.K.
Ockene, F.A. Tylavsky, M.Z. Vitolins and J.R. Hebert. Univ.
of South Carolina, Univ. of Massachusetts Med. Sch., Univ. of
Tennessee Hlth. Sci. Ctr. and Wake Forest Sch. of Med.
C224 II
1034.6
Postprandial inflammatory responses
and plasma-free fatty acids: effects of blueberry intake K.D.
Ono-Moore, R.G. Snodgrass, S. Huang, S. Singh, D. Burnett,
E. Bonnel, L. Woodhouse, T.L. Freytag, S.J. Zunino, J.C.
Rutledge and D.H. Hwang. Univ. of California, Davis, USDA,
Davis and Sch. of Med., Univ. of California, Davis.
C225 I
1034.7
Association of vitamin C with serum uric
acid concentration: The Framingham Third Generation Cohort
S. Sahni, K.M. Mangano, K.L. Tucker, C. Fox, D.P. Kiel, X.
Zhang and M.T. Hannan. IFAR, Hebrew SeniorLife, Harvard
Med. Sch., Univ. of Massachusetts Lowell and NHLBI, Harvard
Med. Sch., Framingham.
C226 II
1034.8
Novel aerobic bacteria: isoflvonesbiotransformation of Pueraria radix extract I. Kim, J-E. Kwon,
H.J. Koo, T-H. Park, E-H. Sohn, S-A. Jang, H-R. Kim and
S.C. Kang. Natl. Acad. of Agr. Sci., Rural Develop. Admin.,
Suwon, Gachon Univ., Daegu Univ. and Kangwon Natl. Univ.,
South Korea.
C227 I
1034.9
Combinatory
mixture
of
Rubus
coreanus and Astragalus membranaceus attenuates bone loss
through RANK signal pathway in ovariectized mice H.J. Koo,
E-H. Sohn and S.C. Kang. Gachon Univ. and Kangwon Natl.
Univ., South Korea.
C228 II
1034.10 Effect of commercial sweetener intake
on the NF-κB and AP-1 pro-inflammatory pathways in liver and
small intestine in mice A. EspinoBarros-Flores, J.A. Estrada,
B. Pliego-Rivero and I. Contreras. Autonomous Univ. of
Mexico State, Toluca.
C229 I
1034.11 Differentiation effect on monolayer
integrity and inflammatory response in Caco2 cells in vitro K.
Racicot, E. Tanzer and C-Y.O. Chen. USDA at Tufts Univ. and
U.S. Army Natick Soldier Res. Develop. & Engin. Ctr.
C230 II
1034.12 Ripening of cheddar cheese with
Lactobacillus helveticus as adjunct culture produces peptides
that protect human vein endothelial cells against inflammatory
markers relevant to cardiovascular disease S. Ravisankar,
J. Yuan, G.R. Munske and G.D. Noratto. Washington State
Univ.
C231 I
1034.13 Investigating omega-3 polyunsaturated
fatty acid and/or soy protein isolate supplementation on renal
inflammation in a rat model of polycystic kidney disease K.H.
Maditz, C. Oldaker, N. Nanda, R. Livengood, V. Benedito
and J. Tou. West Virginia Univ. and West Virginia Univ. Sch. of
Med.
C232 II
1034.14 Effects of mild calorie restriction on
hepatic lipid metabolism and inflammation in mice C.Y. Park,
S. Park, M.S. Kim and S.N. Han. Seoul Natl. Univ.
C233 I
1034.15 Effect of n-3 fatty acids and their
derivatives on the expression of inflammatory genes B. AllamNdoul, F. Guenard, O. Barbier and M-C. Vohl. Inst. of Nutr.
and Funct. Foods, Quebec City and Laval Univ. Med. Res. Ctr.
C234 II
1034.16 All omega 3 fatty acids decrease
macrophage prostaglandin E2 and inflammatory cytokine
production A.R. Pepper-Yowell, S. Wang, O.A. Byelashov,
M.D. Sellers, T.L. Harris and M.A. Ballou. Texas Tech Univ.
and Omega Protein Corp., Houston.
337
T
U
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NUTRITIONTUESDAY
C235 I
1034.17 Overall effect of diet and supplementation
with omega -3 fatty acids on the concentration of IL -6 and
TNF-α in obese adults M.C. Díaz-Gutiérrez, A. TexcahuaSalazar, M. Inturbide-García, F. Charua-Levy, A. ParraCarriedo and C. Hernández-Guerrero. Univ. Iberoamericana,
Mexico City.
C236 II
1034.18 Macrophage expression of activation
markers in iron deficient conditions M.A. Leon Davila, I.
Contreras, R.I. Gutierrez-Sanchez and J.A. Estrada.
Autonomous Univ. of Mexico State.
C237 I
1034.19 The Inflammation and Nutritional
Science for Programs/Policies and Interpretation of Research
Evidence (INSPIRE) project F.A. Ashour and D.J. Raiten.
NICHD, NIH, Rockville.
C238 II
1034.20 Inflammation, vitamin D, and depression
symptoms among reproductive-aged women from the National
Health and Nutrition Examination Survey 2005-2006 J.M. Faraj
and A.G. Ronnenberg. Univ. of Massachusetts Amherst.
1035.MEDICAL NUTRITION: INTERVENTIONS FOR
THE TREATMENT AND PREVENTION OF
NUTRITION-RELATED DISEASES
Poster
(Sponsored by: Medical Nutrition)
C239 I
1035.1
Effect of almonds on cardiovascular risk
factors in Chinese patients with type 2 diabetes mellitus: study
design C-M. Chen, H-T. Li, Y-Y. Liao, J-F. Liu and C-Y.O.
Chen. Shih-Chien Univ., Taiwan, Taipei Med. Univ. Sch. of
Nutr. and Hlth. Sci., Chang Gung Univ. of Sci. and Technol.,
Taiwan and USDA at Tufts Univ.
C240 II
1035.2
Basal energy expenditure in children
with spastic quadriplegic cerebral palsy and severe malnutrition
E.M. Vasquez-Garibay, A.A. García-Contreras, E. RomeroVelarde, I.E. Sandoval Montes, A.I. Ibarra-Gutierrez and
R. Troyo-Sanroman. Univ. of Guadalajara and Civil Hosp. of
Guadalajara.
C241 I
1035.3
Relationships between salt intake and
hypertension in patients with smell loss R.I. Henkin. Ctr. for
Molec. Nutr. and Sensory Disorders, Washington, DC.
C242 II
1035.4
Synergistic effects of leucine with
phosphodiesterase 5 inhibition on insulin sensitivity L. Fu, F.
Li, A. Bruckbauer, Q. Cao, X. Cui, R. Wu, H. Shi, M. Zemel
and B. Xue. Georgia State Univ. and NuSirt Sci. Inc., Knoxville.
C243 I
1035.5
Enrolling the care-givers to improve
chronic stroke patients’ social activity and nutrition — a
randomized controlled trial T.C. Wang, A.C. Tsai, J-Y. Wang,
B.Y. Lin, J.J. Chen and K-L. Lin. Tzu Hui Inst. of Technol.,
Pingtung, Asia Univ., Yuan’s Gen. Hosp., Kaohsiung, Kaohsiung
Municipal Min-sheng Hosp. and Kaohsiung Veterans Gen.
Hosp., Taiwan.
C244 II
1035.6
Relationship
between
baseline
triglyceride concentration and triglyceride reduction with 4
g/d long-chain omega-3 acid ethyl esters K.M. Nieman, M.R.
Dicklin, M. Bell, T.M. Rains and K.C. Maki. Biofortis Clin.
Res., Addison, IL, Biofortis Clin. Res., Addison, IL and ClinData
Svcs., Fort Collins.
338
C245 I
1035.7
Effect of a dietary portfolio (nopal, chia,
soy, oat and inulin) on serum lipoprotein profile in subjects
with metabolic syndrome M. Aguilar, I. Medina, M. Guevara,
M. Radyx, X. Orozco, E. Jimenez, A. Flores, M. CastañoJameson, B. Ayala, N. Vazquez, A.R. Tovar and N. Torres.
Salvador Zubirán Natl. Inst. of Med. Sci. and Nutr., Mexico City.
C246 II
1035.8
Effect of a dietary portfolio (nopal, soy,
oat, chia seed and inulin) on lipoprotein subclasses and LDLcholesterol in Mexican subjects with hypercholesterolemia
N. Vazquez-Manjarrez, M. Guevara, A.R. Tovar, A. Flores,
B. Ayala, M. Radyx, I. Medina, M. Aguilar, E. Jimenez, X.
Orozco, M. Castaño-Jameson and N. Torres. Salvador
Zubirán Natl. Inst. of Med. Sci. and Nutr., Mexico City and
Salvador Zubirán Natl. Inst. of Med. Sci. and Nutr., Mexico City.
C247 I
1035.9
Effect of glutathione S-transferase M1
and Tl polymorphism on the level of plasma antioxidant vitamin
in Korean subclinical hypertensive patients after kale juice
supplementation M-H. Kang, J-H. Han, H-J. Lee and T.S.
Kim. Hannam Univ., South Korea and Pulmuone Hlth. & Living
Co. Ltd., Seoul.
C248 II
1035.10 Relationship of nutrition and bone
mineral density among Hispanic subjects in “En Balance”
diabetes education program D. Damayanti, S. Dehom, Z.R.
Cordero-MacIntyre1, M. De Leon and L. Beeson. Sch. of
Publ. Hlth., Loma Linda Univ. and Ctr. for Hlth. Disparities and
Molec. Med., Loma Linda Univ.
C249 I
1035.11 Teduglutide for safe reduction of
parenteral nutrition requirements in adults: a systematic review
J.K. Naberhuis and K.A. Tappenden. Univ. of Illinois, Urbana.
C250 II
1035.12 Development and clinical trial of an
eHealth program for pre-diabetics G. Block, K. Azar, T. Block,
C. Block and L. Palaniappan. NutritionQuest, Berkeley and
Palo Alto Med. Fndn.
C251 I
1035.13 Self-weighing to prevent age-related
weight gain in young adults F. Bertz, C.R. Pacanowski
and D.A. Levitsky. Cornell Univ. and Univ. of Minnesota,
Minneapolis.
C252 II
1035.14 Butyrate-induced
upregulation
of
intestinal glucose transport represents a possible nutrient
therapy for individuals with malabsorptive disorders H.F.
Mangian, H.F. Mangian and K.A. Tappenden. Univ. of Illinois,
Urbana.
1036.NUTRIENT-GENE INTERACTIONS:
NUTRIENT CONTROL OF PROTEOMICS AND
METABOLOMICS
Poster
(Sponsored by: Nutrient-Gene Interactions RIS)
C253 I
1036.1
Comparison of endocannabinoid actions
on metabolomic analysis of mouse and human myoblast
cultures B.A. Watkins, J. Kim, K.L. Pappan and M.E.
Carlson. Univ. of Connecticut, Farmington and Metabolon,
Durham, NC.
C254 II
1036.2
Bioavailability and metabolomic targets
of sulforaphane in humans L.L. Atwell, J.D. Clarke, A. Hsu,
D. Bella, J.F. Stevens, R.H. Dashwood, D.E. Williams and E.
Ho. Oregon State Univ.
TUESDAYNUTRITION
C255 I
1036.3
Interaction of the protease resistant
proteins with the intestinal mucosa membrane proteins Y. Yum,
J. Lee and J. Lim. Kyungpook Natl. Univ.
1037.NUTRIENT-GENE INTERACTIONS: NUTRIENTGENE INTERACTIONS IN OBESITY AND
INFLAMMATION
Poster
C256 I
1037.1
Low dose of trans-10, cis-12 conjugated
linoleic acid reduces adiposity and increases markers of
thermogenesis in overweight mice W. Shen, J. Baldwin, B.
Collins, L. Hixson, K-T. Lee, T. Herberg, J. Starnes, C-C.
Chuang, T. Reid, S. Gupta and M. McIntosh. Univ. of North
Carolina at Greensboro and Wake Forest Sch. of Med.
C257 II
1037.2
Eicosapentaenoic acid regulation of
muscle lipid metabolism in vivo and in vitro A. Aljawadi, M.
Lemieux, N. Kalupahana, K.J. Claycombe and N. MoustaidMoussa. Texas Tech Univ., Univ. of Peradeniya, Sri Lanka and
USDA, Grand Forks.
C258 I
1037.3
Temporal effects of peroxisome
proliferator-activated receptor γ activation on macrophage
inflammatory responses X. Guo, T. Guo, H. Li, Y. Pei, H. Xu,
T. Qi, X. Hu, Y. Zhao, J. Zhao and C. Wu. Texas A&M Univ.
C259 II
1037.4
Effects of pregnancy vitamin D status
on adipose tissue development and inflammation in lean,
male adult mice offspring A.M. Belenchia, K.L. Jones, D.Q.
Beversdorf, M.J. Will, V.J. Vieira-Potter, R.J. Scroggins
and C.A. Peterson. Univ. of Missouri-Columbia and Univ. of
California, Davis.
C260 I
1037.5
Eicosapentaenoic acid regulates brown
adipose tissue gene expression and metabolism in high fat
fed mice M. Pahlavani, N.S. Kalupahana, M. LeMieux, A.
Aljawadi, S. Scoggin, K. Claycombe and N. MoustaidMoussa. Texas Tech Univ., Univ. of Peradeniya, Sri Lanka and
USDA, Grand Forks.
C261 II
1037.6
Role of Wnt5b in fatty acid synthesis
in primary cultured mouse hepatocytes N. Siriwardhana and
J.H. Kim. Univ. of Tennessee, Knoxville and Marshall Univ.
Sch. of Med.
C262 I
1037.7
Lipoprotein lipase variants interact
with polyunsaturated fatty acids to modulate obesity traits
in Puerto Ricans Y. Ma, K.L. Tucker, C.E. Smith, Y-C. Lee,
T. Huang, C-Q. Lai, L.D. Parnell, K. Richardson and J.M.
Ordovas. IMDEA Food Inst., Madrid, USDA at Tufts Univ.,
Univ. of Massachusetts Lowell and Natl. Cr. for Cardiovasc.
Res. (CNIC), Madrid.
C263 II
1037.8
Changes in signaling pathways through
NOD2 in high fat diet-induced obesity is associated with
inflammatory response in immune cells M.S. Kim, H-K. Kim,
C.Y. Park, J.M. Park and S.N. Han. Seoul Natl. Univ. and
Catholic Univ. of Korea.
C264 I
1037.9
Gene-diet interaction effects during
a supplementation with n-3 PUFA on both plasma and gene
expression levels of inflammatory markers H. Cormier, I.
Rudkowska, P. Couture, S. Lemieux and M-C. Vohl. Inst.
of Nutr. and Funct. Foods, Quebec City and CHU de Québec
Res. Ctr.
C265 II
1037.10 Effect
of
diet
intervention
on
inflammation-related gene expression in CD14+ circulating
monocytes from metabolic syndrome patients L. Martin, S.K.
Deo and D.D. Sears. UCSD.
C266 I
1037.11 Theobromine suppresses adipocyte
differentiation through the MAPK pathway in 3T3-L1
preadipocytes Y. Jang, J. Kim, H. Lee and S. Pyo.
Sungkyunkwan Univ., South Korea.
C267 II
1037.12 Role for dusp4 in modulating PPARγ
activity by covalent modification in adipocytes W. Guo, B.S.
Ferguson, H. Nam, R.G. Hopkins and R.F. Morrison. Univ.
of North Carolina at Greensboro.
C268 I
1037.13 Microflora changes with an acute high
fat diet C.H. Gonzalez, L. Haar, M. Engevik and W.K. Jones.
Univ. of Cincinnati.
1038.NUTRIENT-GENE INTERACTIONS: NUTRIENTGENE INTERACTIONS IN METABOLIC,
AUTOIMMUNE AND NEURODEGENERATIVE
DISEASES
Poster
C269 I
1038.1
Polymorphisms in the MGLL gene are
associated with plasma LDL-C response to a marine n-3 PUFA
supplementation C. Ouellette, H. Cormier, I. Rudkowska, S.
Lemieux, P. Couture and M-C. Vohl. Laval Univ. and CHU de
Québec Res. Ctr.
C270 II
1038.2
Hepcidin plays a key role in 6-OHDA
induced iron overload and apoptotic cell death in a cell culture
model of Parkinson’s disease Q. Xu, A.G. Kanthasamy, H. Jin
and M.B. Reddy. Iowa State Univ.
C271 I
1038.3
The CETP polymorphism rs5882 is
associated with triglyceride lowering in response to plant sterol
consumption D.S. MacKay, P.K. Eck, D.J. Baer and P.J.
Jones. Univ. of Manitoba and USDA.
C272 II
1038.4
The impact of dairy consumption on
circulating cholesterol levels is modulated by common single
nucleotide polymorphisms in cholesterol synthesis- and
transport-related genes M. Abdullah, A. Cyr, M-È. Labonté,
M-C. Lépine, P. Couture, P. Eck, B. Lamarche and P. Jones.
Richardson Ctr. for Funct. Foods and Nutraceuts., Winnipeg,
Univ. of Manitoba and Inst. of Nutr. and Funct. Foods, Quebec
City.
C273 I
1038.5
Early
infant
feeding
and
islet
autoimmunity in The Environmental Determinants of Diabetes
in the Young (TEDDY) Study U. Uusitalo, H-S. Lee, C. Andren
Aroonsson, K. Vehik, J. Yang, S. Hummel, M. Butterworth,
A. Lernmark, M. Rewers, W. Hagopian, J-X. She, O. Simell,
A. Ziegler, B. Akolkar, J. Krischer, S.M. Virtanen and J.M.
Norris. Univ. of South Florida, Lund Univ., Diabetes Res. Inst.,
Munich, Barbara Davis Ctr. for Childhood Diabetes, Aurora,
Pacific Northwest Diabetes Res. Inst., Med. Col. of Georgia,
Univ. of Turku, NIAID, NIH, Natl. Inst. for Hlth. and Welfare,
Helsinki and Colorado Sch. of Publ. Hlth.
339
T
U
E
NUTRITIONTUESDAY
1039.ENERGY AND MACRONUTRIENT METABOLISM:
CARBOHYDRATE METABOLISM
Poster
(Sponsored by: Energy and Macronutrient Metabolism
RIS)
C274 I
1039.1
No effect of the type of sugar on ectopic
fat storage J. Lowndes, S. Bravo, S. Sinnett, R. Jordan, K.
Grench and J. Rippe. Rippe Lifestyle Inst., Celebration, FL
and Sand Lake Imaging, Maitland, FL.
C275 II
1039.2
Snacking
influences
adipokine
concentration independent of body composition and
inflammation in overweight humans Z. Clayton, E. Fusco, L.
Kass, J. Carpenter, S. Hooshmand, M.Y. Hong and M. Kern.
San Diego State Univ.
C276 I
1039.3
Effects of an acute fructose or fructose
and glucose load in a test meal on fructose disposal F. Theytaz,
S. De Giorgi, N. Stefanoni, V. Rey, L. Hodson, B.A. Fielding,
V. Lecoultre, P. Schneiter and L. Tappy. Univ. of Lausanne
and Univ. of Oxford.
C277 II
1039.4
Chronic intake of honey, sugar and high
fructose corn syrup exert equivalent effects on glucose and
insulin S. Raatz, K. Beals, L. Johnson and M. Picklo. USDA,
Grand Forks, Univ. of Minnesota and Univ. of Utah.
C278 I
1039.5
Carbohydrate-rich snacks influence
plasma glucose, insulin and ghrelin responses in overweight
adults E. Fusco, Z. Clayton, L. Kass, J. Carpenter, S.
Hooshmand, M.Y. Hong and M. Kern. San Diego State Univ.
C279 II
1039.6
Effect of hummus on postprandial
glucose and insulin responses in healthy individuals C.W.
Kendall, A. Esfahani, J. Campbell, A. Jenkins and D.J.
Jenkins. Univ. of Toronto, St. Michael’s Hosp., New York Med.
Sch. and Glycemic Index Labs., Toronto.
C280 I
1039.7
Glycemic response to high-amylose
rice in humans M.L. Stewart and A. Zenel. Univ. of Hawaii at
Manoa.
C281 II
1039.8
Slower in vivo glucogenesis from starch
oligomers by mucosal sucrase-isomaltase A.H-M. Lin, A.
Muniandy, M. Diaz-Sotomayor, S.E. Avery, S.K. Chacko,
L-K. Yan, R. Quezada-Calvillo, B.R. Hamaker and B.L.
Nichols. Purdue Univ., Baylor Col. of Med. and Autonomous
Univ. of San Luis Potosi, Mexico.
C282 I
1039.9
Elucidating
a
mechanism
for
maltooligosacchride sensing at the small intestine enterocyte
M. Chegeni, C.Y. Kim, H.Y. Naim and B.R. Hamaker. Purdue
Univ. and Univ. of Vet. Med., Hannover.
C283 II
1039.10 Relationship of in vitro and in vivo
approaches on slow appearance rate of starch: a meta-analysis
S. Vinoy, A. Goux, N. Jourdan-Salloum, A. Lesdema and
A. Meynier. Mondelez Int. R&D, Saclay and BIOptimize,
Cormontreuil, France.
C284 I
1039.11 Sorghum starch is well digested in
developmental pancreatic α-amylase insufficient children
in Mali F. Cisse, H.G. Diall, A. Rahmanifar, M. Sylla, A.R.
Opekun, M.A. Grusak, A.H-M. Lin, B.L. Nichols and B.R.
Hamaker. Inst. of Rural Econ., Mali, Purdue Univ., Hosp. Ctr.
and Univ. Gabriel Toure, Mali, Nutr. Consultant, West Lafayete
and Baylor Col. of Med.
340
1040.ENERGY AND MACRONUTRIENT METABOLISM:
DIET AND/OR EXERCISE REGULATION OF
FOOD INTAKE
Poster
(Sponsored by: Energy and Macronutrient Metabolism
RIS and Obesity RIS)
C285 I
1040.1
Dried plum snacking influences nutrient
intake in individuals with metabolic syndrome, prediabetes,
and overweight B. Reiter, Z. Clayton, E. Fusco, L. Kass, J.
Carpenter, S. Hooshmand, M.Y. Hong and M. Kern. San
Diego State Univ.
C286 II
1040.2
Effect of resistant starch on subjective
appetite and food intake in healthy adults J. Hollis, C.
Hutchison and W. Hsu. Iowa State Univ.
C287 I
1040.3
Food perception and neurocorrelates of
evoked brain activity A.K. Thaw and E. Graves. Millsaps Col.,
MS.
C288 II
1040.4
Addition of protein or fiber to pasta does
not alter satiety or mid-afternoon snacking in healthy men and
women R. Korczak, R. Ahnen, D. Timm, J.L. Slavin and W.
Thomas. Univ. of Minnesota, St. Paul and Minneapolis.
C289 I
1040.5
The effect of almond consumption on
satiety and the postprandial metabolic response in high-risk
pregnant women M.N. Henderson, L. Sawrey-Kubicek, K.
Mauldin and J. King. Children’s Hosp. Oakland Res. Inst. and
California State Univ., San Jose.
C290 II
1040.6
The effect of solid, semi-solid and
fluid snacks on food intake and satiety in children A.C-Y. Li,
B.J. Gheller, M.E. McCormick, N. Bellissimo, Y. Anini, F.
Nunes, J. Hamilton, R.C. Mollard, G.H. Anderson and B.L.
Luhovyy. Mount Saint Vincent Univ., Halifax,Ryerson Univ.,
Toronto, Dalhousie Univ., Halifax and Univ. of Toronto.
C291 I
1040.7
Molecular and metabolomic effects
of voluntary running wheel activity on skeletal muscle in late
middle-aged rats S.M. Garvey, D.W. Russ, M.B. Skelding,
L.A. Reaves, I. Boyd and N.K. Edens. Abbott Nutr., Columbus,
Ohio Univ. and Ohio Univ. Heritage Col. of Osteo. Med.
C292 II
1040.8
A pre-meal glucose drink, but not video
game playing, suppresses food intake in overweight and obese
boys B.J. Gheller, T. Akhavan, D. Pollard, B. Gladanac, M.
Constantino, B.L. Luhovyy and N. Bellissimo. Mount Saint
Vincent Univ. and Ryerson Univ., Canada.
1041.VITAMINS AND MINERALS: WATER AND FAT
SOLUBLE VITAMINS AND CHRONIC DISEASE
Poster
(Sponsored by: Vitamins and Minerals RIS)
C293 I
1041.1
Vitamin D Intake among adults of
varying age, race, and gender A. Bailey, D. Gonzales, T.
Crook and R. Hakkak. Univ. of Arkansas for Med. Sci.
TUESDAYNUTRITION
C294 II
1041.2
Vitamin D deficiency impairs quadriceps
strength without modulating inflammatory cytokines in patients
with knee osteoarthritis T. Barker, V.T. Henriksen, V.E.
Rogers, D. Aguirre, R.H. Trawick, G.L. Rasmussen and
N.G. Momberger. The Orthopedic Specialty Hosp., Murray,
UT.
C295 I
1041.3
Dietary resistant starch prevents urinary
excretion of vitamin D metabolites and restores circulating
25-hydroxycholecalciferol concentrations in the Zucker diabetic
fatty rat G.Y. Koh, K. Mancosky, Y-T. Loo, K. Grapentine, E.
Bowers and M.J. Rowling. Iowa State Univ.
C296 II
1041.4
Comparison of tissue concentrations
in male and female C57BL/6 mice in response to vitamin K
manipulation S.G. Harshman, D. Smith, J.P. Karl, X. Shen,
S. Booth and X. Fu. USDA at Tufts Univ.
C297 I
1041.5
A randomized controlled trial of vitamin
D supplementation in pregnancy: effects on vitamin D status
and clinical outcomes M. Zerofsky, B. Jacoby and C.B.
Stephensen. Univ. of California, Davis, Univ. of California
Davis, Sacramento and USDA, Davis.
C298 II
1041.6
1, 25-Dihydroxyvitamin D3/Vit D
receptor suppresses brown adipocyte differentiation and
mitochondrial biogenesis C. Ricciardi, J. Bae, P. Hu, D.
Esposito, S. Komarnytsky, J. Chen and L. Zhao. Univ. of
Tennessee, Knoxville, North Carolina State Univ., Kannapolis
and North Carolina State Univ.
C299 I
1041.7
Vitamin E status of the U.S. adult
population by use of dietary supplements M.I. McBurney, E.
Yu, E.D. Ciappio, J.K. Bird, M. Eggersdorfer, E. Stoecklin
and S. Mehta. DSM Nutr. Products LLC, Parsippany, Cornell
Univ., DSM Nutr. Products LLC, Parsippany, NJ, DSM Nutr.
Products LLC, Delft, Netherlands and DSM Nutr. Products
LLC, Kaiseraugst, NJ.
C300 II
1041.8
Resistant starch promotes vitamin D
balance and maintenance of methyl group metabolism in type
1 diabetic rats A. Anderegg and K. Schalinske. Iowa State
Univ.
C301 I
1041.9
Whole egg protein markedly increases
blood vitamin D concentrations in male Sprague-Dawley rats
K. Van Wyk and K. Schalinske. Iowa State Univ.
C302 II
1041.10 The relationship between vitamin D
status and markers of diabetes risk in individuals at risk for
developing diabetes: preliminary data from the Evidence trial
T.S. Moreira-Lucas and T.M. Wolever. Univ. of Toronto.
C303 I
1041.11 Effects of high fat diet-induced obesity
on expression of genes involved in vitamin D metabolism in
mice J.M. Park, C.Y. Park and S.N. Han. Seoul Natl. Univ.
C304 II
1041.12 High rates of riboflavin deficiency in
women of childbearing age in Cambodia and Canada K.C.
Whitfield, A. McCann, C. Karakochuk, A. Talukder, M.
Ward, H. McNulty, J. McLean and T.J. Green. Univ. of British
Columbia, Univ. of Ulster and Helen Keller Intl., Phnom Penh.
C305 I
1041.13 Dynamic
vitamin
A
metabolism
contributes to the regulation of hepatic glucose and lipid
metabolism in response to different physiological conditions Y.
Li and G. Chen. Univ. of Tennessee, Knoxville.
C306 II
1041.14 Role of thioredoxin-binding protein
2 in cardiac oxidative stress and energy metabolism of rats
supplemented with vitamin D P.P. Santos, B.P. Rafacho, A.F.
Gonçalves, V. Pires, A.A. Fernandes, M.F. Minicucci, P.
Azevedo, M.P. Okoshi, L.A. Zornoff and S.A. Paiva. São
Paulo State Univ.
C307 I
1041.15 Serum 25-hydroxy vitamin D is
associated with blood total cholesterol and diastolic blood
pressure in a young multi-ethnic group living in South Florida
S. Ajabshir, J. Exebio, G.G. Zarini, A. Nayer, J. Vaccaro,
L.H. Shaban and F.G. Huffman. Florida Intl. Univ., Univ. of
Miami and Kuwait Univ., Col. for Women.
1042.VITAMINS AND MINERALS: MICRONUTRIENT
BIOAVAILABILITY AND ANTIOXIDANT
FUNCTION
Poster
C308 I
1042.1
Novel pathway for iron deficiency in
pediatric non-alcoholic steatohepatitis D. Moya, S.S. Baker,
W. Liu, M. Garrick, R. Kozielski, R.D. Baker and L. Zhu.
Univ. at Buffalo, SUNY.
C309 II
1042.2
Ascorbate-induced
iron
transport
through ferroportin involves IRP2 and HIF2α N.M. Scheers
and A-S. Sandberg. Chalmers Univ. of Technol., Sweden.
C310 I
1042.3
Biofortified pearl millet (Pennisetum
glaucum L. provides more bioavailable iron than standard
pearl millet: studies in poultry (Gallus gallus) and an in vitro
digestion/Caco-2 model E. Tako, B. Cherian, S. Reed, J.
Budiman and R.P. Glahn. USDA, Ithaca, Intl. Food Policy
Res. Inst., Washington, DC and Cornell Univ.
C311 II
1042.4
Iron bioavailability of low and high phytic
aid maize produced via recurrent selection A. Beavers, P.
Scott, A. Moran Lauter, S. Goggi and M. Reddy. Iowa State
Univ. and USDA, Ames.
C312 I
1042.5
The effect of nitrogen treatment on the
anthacyanine and polyphenols content and ORAC factor of
Aronia melanocarpa grown in Maryland T. Ndam, B. Aroh, B.
Volkis, A. Ristvey, S. Mathew and V. Volkis. Univ. of Maryland
Eastern Shore and Univ. of Maryland Ext., Queenstown.
C313 II
1042.6
Effects of high-fat high-carbohydrate
diet on pentylenetetrazole seizure threshold in rat Z.A. Hasan
and K.H. Alzoubi. Col. of Med. and Med. Sci., Arabian Gulf
Univ., Bahrain and Jordan Univ. of Sci. and Technol.
C314 I
1042.7
Mineral content and in vitro iron
bioavailability in seaweeds M.A. Dunn, S. Flores and J.
Dobbs. Univ. of Hawaii.
C315 II
1042.8
The bioavailability iron, zinc and
copper in the rat due to their interactions D.T. Gordon and
M. Ellersick. PIC&PC, Cathlamet, WA and Univ. of MissouriColumbia.
C316 I
1042.9
The study on the impact of lysine-sugar
Maillard reaction products on human intestinal microbiome
C-O. Hong, Y-C. Koo, M-H. Nam, S-Y. Yang and K-W. Lee.
Korea Univ.
C317 II
1042.10 Low serum levels of trace elements
(iron, zinc and copper) is associated with increasing number of
pregnancies among Omani women: a case-control study M.I.
Waly. Sultan Qaboos Univ., Oman.
341
T
U
E
NUTRITIONTUESDAY
1043.VITAMINS AND MINERALS: ZINC
Poster
Poster
(Sponsored by: Dietary Bioactive Components RIS)
C318 I
1043.1
Effect of vegetarian diets on zinc status:
a systematic review and meta-analysis of studies in humans S.
Samman and M. Foster. Univ. of Sydney.
C319 II
1043.2
Dietary
zinc
deficiency
affects
blood linoleic acid:dihomo-γ-linolenic acid ratio: a sensitive
physiological marker of zinc status in vivo (Gallus gallus) S.
Reed, X. Qin, R. Ran-Ressler, J.T. Brenna, R.P. Glahn and
E. Tako. Cornell Univ. and USDA, Ithaca.
C320 I
1043.3
Marginal zinc intake impairs mammary
gland involution, increases oxidative stress and disrupts ductal
integrity abrogating the protective effect of lactation on breast
tumorigenesis in a mouse model R.P. Mack, Z. Bostanci, S.
Alam, S. Lee, D.I. Soybel and S.L. Kelleher. Penn State and
Penn State Hershey Col. of Med.
C321 II
1043.4
Zinc supplementation decreased ZIP4
mRNA abundance in peripheral blood mononuclear cells of
rural women in south Ethiopia A. Bogale, S.L. Clarke and B.J.
Stoecker. Oklahoma State Univ. and Hawassa Univ., Ethiopia.
C322 I
1043.5
Validation of mineral analytical method
for food composition data-up construction J. Hwang, M. Oh,
S. Kim, S-n. Kim and J-s. Nam. Korea Food Res. Inst.,
Seongnam-si, Natl. Acad. of Agr. Sci., Suwon and Suwon
Women’s Col., South Korea.
C323 II
1043.6
The relationship between toenail Zn
and glycemic control in healthy adults O. Lee, Y. Chung and
J. Moon. Yongin Univ. and Korea Atomic Energy Res. Inst.,
Daejeon.
C324 I
1043.7
Effect of wheat germ zinc on growth in
rats and mice: application for estimating relative availability of
dietary zinc K. Yokoi and A. Konomi. Seitoku Univ. Grad. Sch.
and Teikyo Heisei Univ., Japan.
C325 II
1043.8
Changes of gene expressions in zinc
deficiency and diet restriction in rats A. Konomi and K. Yokoi.
Teikyo Heisei Univ. and Seitoku Univ. Grad. Sch., Japan.
C326 I
1043.9
Relationship between plasma zinc
concentrations and clinical signs of zinc deficiency K.R.
Wessells, J.C. King and K.H. Brown. Univ. of California,
Davis and Children’s Hosp. of Oakland Res. Inst.
C327 II
1043.10 Low-abundance
plasma
protein
differences between African-American and Caucasian early
pubertal females following supplementation with 9 mg Zn A.
Grider, R. Lewis, E. Laing and K. Wickwire. Univ. of Georgia.
C328 I
1043.11 Comparison of thymulin activity to other
measures in marginally zinc deficient rats R. DiSilvestro and
E. Joseph. The Ohio State Univ.
342
1044.DIETARY BIOACTIVE COMPONENTS:
BIOAVAILABILITY, METABOLISM AND
BIOMARKERS OF DIETARY BIOACTIVE
COMPONENTS
C329 I
1044.1
Fabrication
of
self-assembled
(-)-epigallocatechin gallate (EGCG) ovalbumin-dextran
conjugate nanoparticles and their transport across monolayers
of human intestinal epithelial Caco-2 cells Z. Li and L. Gu.
Univ. of Florida.
C330 II
1044.2
Effect of processed Atlantic horse
mackerel (Trachurus trachurus) on some hematological indices
and enzyme activities in selected rat tissues O.T. Adeyemi,
O. Osilesi, O.O. Adebawo, F.D. Onajobi, S.O. Oyedemi and
A.J. Afolayan. Babcock Univ., Nigeria and Univ. of Fort Hare
Alice, South Africa.
C331 I
1044.3
Urinary proanthocyanidin A2 as a
biomarker of consumption of cranberry juice — a pilot study
C-Y.O. Chen, C.A. Zampariello and J.B. Blumberg. USDA at
Tufts Univ.
C332 II
1044.4
Development of GC-MS method for
quantification of phenolic acids after in vitro fecal fermentation
A.E. Quirós-Sauceda, M. Clark, K. Racicot, D.A. Polasky,
G.A. González-Aguilar, J.B. Blumberg and C-Y.O. Chen.
USDA at Tufts Univ. and Res. Ctr. for Food Develop.,
Hermosillo, Mexico.
C333 I
1044.5
Differential
cellular
uptake
and
metabolism of curcuminoids in monocytes/macrophages:
regulatory effects on lipid accumulation K. Nakagawa, J-M.
Zingg, S.H. Kim, M.J. Thomas, G.G. Dolnikowski, A. Azzi, T.
Miyazawa and M. Meydani. USDA at Tufts Univ. and Tohoku
Univ., Japan.
C334 II
1044.6
A single ascending dose, initial clinical
pharmacokinetic and safety study of ursolic acid in healthy
adult volunteers S.P. Hirsh, L.G. Huber, P. Zhang, R.A. Stein
and S.V. Joyal. Life Ext. Clin. Res. Inc., Fort Lauderdale.
C335 I
1044.7
Strain-specific profiles of hepatic
xanthones in mice chronically fed α-mangostin, the
most abundant xanthone in mangosteen fruit C.
Chitchumroonchokchai, E. Mah, F. Gutierrez-Orozco, R.S.
Bruno and M.L. Failla. The Ohio State Univ.
C336 II
1044.8
Enhanced bioaccessibility and transport
of reduced coenzyme Q10 is dependent on GSH status in
Caco-2 human intestinal epithelial cells M.L. Failla and C.
Chitchumroonchokchai. The Ohio Sate Univ.
C337 I
1044.9
Melibiose, a non-digestible saccharide,
promotes absorption of quercetin glycosides in rat small
intestine with a novel mechanism S. Tanaka, A. Shinoki and
H. Hara. Hokkaido Univ.
C338 II
1044.10 Cytokine
release
by
Jurkat
T-lymphocytes is modulated following treatment with
polyphenols or Lactobacillus rhamnosus probiotic extracts S.H.
Richardson, C. Ford, A. Crozier, F. McArdle, A. McArdle
and M.J. Jackson. Univ. of Liverpool and Sch. of Chem., Univ.
of Glasgow.
TUESDAYNUTRITION
C339 I
1044.11 Antibiotics that prevent endotoxemia do
not reduce the ability to ferment high amylose maize resistant
start (HAMRS2) in rats D. Carvajal-Aldaz, D. Coulon, T.
Chaves, A.M. Raggio, R.J. Martin, R. Stoutt, T. Gauthier,
H. Durham, C. Pelkman and M. Keenan. LSU AgCtr., USDA,
Davis, LSU A&M, Pennington Biomed. Res. Ctr., Baton Rouge
and Ingredion, Bridgewater, NJ.
C340 II
1044.12 The effect of individual milk proteins
on bioaccessibility of green tea flavan-3-ols S. Moser, M.
Chegeni, A. Liceaga, O. Jones and M. Ferruzzi. Purdue
Univ.
C341 I
1044.13 Combination of modified formulation
and bioprocessing techniques as a way to improve nutritional
and health potential of bread V. Garcia Campayo, S. Han, D.
Gaspard, W.R. Aimutis and J. Casper. Cargill Inc. and Cargill
Horizon Milling, MN.
C342 II
1044.14 Antioxidant bioaccessibility from wheat
aleurone throughout the canine gastrointestinal tract: an in
vitro study V. Garcia Campayo, S. Han, W.R. Aimutis, D.
Bosscher and A. Franck. Cargill Inc., Wayzata, MN and
Cargill R&D Ctr. Europe, Vilvoorde, Belgium.
C343 I
1044.15 A nano-emulsion of lutein is more
effective than regular lutein in reducing hepatic inflammation
in guinea pigs G. Murillo, D. Aguilar, A. Missimer, S.
Kakumanu, R.J. Nicolosi, B. Bolling and M.L. Fernandez.
Univ. of Connecticut and Covaris Inc., Billerica, MA.
C344 II
1044.16 Enhance intestinal lymphatic transport
of lipophilic bioactive food components by nanoemulsion
delivery system M. Yao, J. Zheng, D.J. Mcclements and H.
Xiao. Univ. of Massachusetts Amherst.
C345 I
1044.17 Neusilin®
influences
curcumin
bioavailability and anti-depressant efficacy in rats L. Xie, S.
Yohn, J. Salamone, R. Bogner and B. Bolling. Univ. of
Connecticut.
C346 II
1044.18 Assessment of nutritional status in
subjects of MonaVie product users and non-users — a cross
sectional study D. Quan, W.W. Xiong and S. Talbott. Xel
Pharmaceuts. Inc., Draper, UT and MonaVie Corp., Lisle, IL.
C347 I
1044.19 A quercetin nanoemulsion enhances
oral bioavailability and hepatic accumulation of quercetin Y.
Guo, T.H. Tran, X. Lu and R.S. Bruno. The Ohio State Univ.
and Univ. of Connecticut.
C348 II
1044.20 Assessment of nutritional status in
subjects of non-MonaVie product users, before and after
supplementation — a longitudinal study D. Quan, W.W.
Xiong and S. Talbott. Xel Pharmaceuts. Inc., Draper, UT and
MonaVie Corp., South Jordan, UT.
C349 I
1044.21 Bioaccessibility of carotenoids and
their distribution in lipoprotein fractions: comparison from two
different sources in a randomized clinical trial H.M. Ok, H.Y.
Jung, M.Y. Park, G-M. Do and O. Kwon. Ewha Womans
Univ., South Korea.
C350 II
1044.22 Biotransformation
of
citrus
polymethoxyflavones in rats and mice J. Zheng, M. Song,
P. Qiu, P. Dong, X. Cai and H. Xiao. Univ. of Massachusetts
Amherst and Ocean Univ. of China.
C351 I
1044.23 The
bioaccessibility
of
phenolic
compounds from pineapple, mango and papaya are not
compromised by their dietary fiber but to their amylaceous
carbohydrates G.E. Velderrain-Rodriguez, G. GonzálezAguilar, J.F. Ayala-Zavala, A. Wall-Medrano, H. AstiazaránGarcía, R.M. Robles-Sanchez and S.G. Sáyago-Ayerdi. Ctr.
for Food and Res. Develop. AC, Hermosillo, Autonomous Univ.
of Ciudad Juarez, Univ. of Sonora and Technol. Inst. of Tepic,
Mexico.
C352 II
1044.24 Enhanced
oral
bioavailability
of
quercetin by nanostructured lipid carriers M. Sun, S. Wang, S.
Nie and J. Zhang. Texas Tech Univ.
C353 I
1044.25 A new biomarker for quinoa intake
A.B. Ross and O. Savolainen. Chalmers Univ. of Technol.,
Sweden.
1045.DIETARY BIOACTIVE COMPONENTS:
MECHANISMS OF ACTION AND MOLECULAR
TARGETS OF DIETARY BIOACTIVE
COMPONENTS
Poster
(Sponsored by: Dietary Bioactive Components RIS)
C354 I
1045.1
Flavonoids and saponins extracted from
black bean (Phaseolus vulgaris L.) seed coats modulate lipid
metabolism and biliary cholesterol secretion in C57BL/6 mice
R.A. Chavez Santoscoy, J.A. Gutierrez-Uribe, S.O. SernaSaldivar, N. Torres and A.R. Tovar. Sch. of Biotechnol. and
Nutr., Monterrey Campus, Mexico and Salvador Zubirán Natl.
Inst. of Med. Sci. and Nutr., Mexico City.
C355 II
1045.2
Ocular endoplasmic reticulum stress
and inflammation is attenuated by supplementation with
muscadine grape polyphenols in vitro and in vivo J-H. Ha, L.
Gu, Q. Li and S. Chung. Univ. of Florida.
C356 I
1045.3
Peptides derived from extruded
amaranth (Amaranthus hypochondriacus) improved the antiinflammatory effect in LPS-induced human THP-1 and mouse
RAW 264.7 macrophages by preventing the activation of NFκB pathway A. Montoya-Rodríguez, E.G. De Mejia, V.P. Dia,
C. Reyes-Moreno and J. Milán-Carrillo. Univ. of Illinois,
Urbana and Autonomous Univ. of Sinaloa, Mexico.
C357 II
1045.4
Effect of high hydrostatic pressure
extract of Korean ginseng on adipogenesis in 3T3-L1
adipocytes S. Oh, M-S. Lee, S. Jung, C-T. Kim and Y. Kim.
Ewha Womans Univ., South Korea and Korea Food Res. Inst.,
Seongnam.
C358 I
1045.5
Broccoli bioactives inhibit human
prostate cancer cell invasions in vitro C-Y. Huang, E.H. Jeffery
and J.W. Erdman. Univ. of Illinois at Urbana-Champaign.
C359 II
1045.6
Mango and pomegranate polyphenolics
in the modification of microbiota and short chain fatty acids in
DSS-induced colitis H. Kim, Y. Minamoto, M.E. Markel, J.
Suchodolski, S. Talcott and S.U. Mertens-Talcott. Texas
A&M Univ.
C360 I
1045.7
1’-Acetoxychavicol acetate inhibits
adipogenesis in 3T3-L1 adipocytes and in high fat-fed rats A.
Kojima-Yuasa, R. Ohnishi, Y. Deguchi, K. Yaku, M. Tabuchi,
H. Munakata and I. Matsui–Yuasa. Grad. Sch. of Human Life
Sci., Osaka City Univ. and Kinki Univ. Med. Sch., Japan.
C361 II
1045.8
Brassicaceae spp. spout extract
inhibits ROS production induced by bisphenol A during the
differentiation of 3T3-L1 preadipocytes J.S. Lee, Y-J. Lee, J-H.
Kim, D-B. Kim, Y-H. Kim, O-H. Lee and J-H. Lim. Kangwon
Natl. Univ., South Korea and Korea Food Res. Inst., Seongnam.
343
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NUTRITIONTUESDAY
C362 I
1045.9
Glucoraphanin
and
glucoraphenin
suppressed lipid accumulation and ROS production induced
by bisphenol A during the adipogenesis in 3T3-L1 cells J-H.
Lim, J-H. Kim, Y-J. Lee, D-B. Kim, Y-H. Kim, J.S. Lee and
O-H. Lee. Korea Food Res. Inst., Seongnam and Kangwon
C363 II
1045.10 Mapping the response of hepatic human
fibroblast growth factor 21 promoter to nutrient availability
R. Moreau, X. Yi, A. Pashaj and M. Xia. Univ. of NebraskaLincoln.
C364 I
1045.11 Degradation of chromatin modifiers,
histone deacetylases, by Spirulina platensis extracts in
macrophages T.X. Pham and J-Y. Lee. Univ. of Connecticut.
C365 II
1045.12 Capscoside G suppresses adipogenesis
by regulating the expression of adipogenic transcription factors
and the activation of AMP-activated protein kinase J. Sung, Y.
Lim and J. Lee. Chungbuk Natl. Univ., South Korea.
C366 I
1045.13 Anti-adipogenic and anti-inflammatory
mechanism of nobiletin in co-culture of adipocyte and
macrophage J. Lee and S. Namkoong. Chungbuk Natl. Univ.,
South Korea.
C367 II
1045.14 Anti-inflammatory bioactives in Alaskan
seaweed: implications in metabolic syndrome J. Kellogg, D.
Esposito, S. Komarnytsky and M.A. Lila. North Carolina
State Univ., Kannapolis.
C368 I
1045.15 Sulforaphane
influences
histone
methylation in advanced prostate cancer cells G. Watson, S.
Wickramasekara, Z. Palomera-Sanchez, C. Black, C. Maier,
D. Williams, R.H. Dashwood and E. Ho. Oregon State Univ.
and Ctr. for Epigenet. and Dis. Prevent., Houston.
C369 II
1045.16 γ-Conglutin, the lupin seed glucoselowering glycoprotein, interferes on insulin pathway in Hep G2
cells A. Parolari, C. Manzoni, F. Faoro, M.M. Duranti and
M.R. Lovati. Univ. of Milan.
C370 I
1045.17 Peptide from α’ chain of 7S soy globulin
lowers plasma lipids through SREBP-2 and PCSK9 pathways
in cholesterol-fed rats M.R. Lovati, A. Parolari, S. Castiglioni
and C. Manzoni. State Univ. of Milan.
C371 II
1045.18 Antioxidant
and
anti-proliferative
capacity of extractable phytochemicals from tropical fruits
(pineapple, mango and papaya) F.J. Olivas-Aguirre, G.E.
Velderrain-Rodriguez, A. Wall-Medrano, G. GonzálezAguilar, R.E. Robles-Zepeda and H. Astiazarán-García.
Autonomous Univ. of Ciudad Juarez, Ctr. for Food Res. and
Develop. AC, Hermosillo and Univ. of Sonora, Mexico.
C372 I
1045.19 Impact of allicin on enzyme activity,
cytokine secretion, and gene expression dynamics in
oxidatively-stressed epithelial cells N.L. Horn, K.M. Ajuwon,
G. Miller and O. Adeola. Purdue Univ. and Biomatrix,
Princeton, MN.
C373 II
1045.20 Compounds from rosemary and
Mexican oregano are natural inhibitors of dipeptidyl peptidaseIV, a target for type-2 diabetes management A.M. Bower, L.M.
Real-Hernandez, M.A. Berhow and E.G. de Mejia. Univ. of
Illinois, Urbana and USDA, Peoria.
C374 I
1045.21 Trigonelline and 3,3-diindolymethane
regulate cell growth in non-malignant colonocytes via estrogen
signaling G. Yoo and C.D. Allred. Texas A&M Univ.
C375 II
1045.22 Role of polyphenol-rich blackcurrant and
black chokeberry extracts in the stimulation of transintestinal
cholesterol excretion in vitro B. Kim, Y-K. Park, S.I. Koo and
J-Y. Lee. Univ. of Connecticut.
344
C376 I
1045.23 Priming of the antiviral immune
transcriptome by a mixed flavonoid-fish oil supplement in
adult overweight women L. Cialdella-Kam, D.C. Nieman,
A.M. Knab, R.A. Shanely, M.P. Meaney, F. Jin, W. Sha and
S. Ghosh. Case Western Univ., Appalachian State Univ.,
Kannapolis, Queens Univ. of Charlotte, Dole Nutr. Res. Lab.,
Kannapolis, Univ. of North Carolina at Charlotte, Kannapolis
and Duke-NUS. Grad. Med. Sch., Singapore.
C377 II
1045.24 (-)-Epigallocatechin 3-gallate decreases
markers of inflammation in a mouse model of ulcerative colitis
Z.T. Bitzer and J. Lambert. Penn State.
C378 I
1045.25 Effect of the high hydrostatic pressure
extract of Korean ginseng on hepatic lipid metabolism and
AMP-activated protein kinase activation in HepG2 cells M-S.
Lee, Y. Shin and Y. Kim. Ewha Womans Univ., South Korea.
C379 II
1045.26 Inhibition of individual subunits of
maltase-glucoamylase and sucrase-isomaltase by polyphenols
M. Simsek, R. Quezada-Calvillo, B.L. Nichols and B.R.
Hamaker. Purdue Univ., Autonomous Univ. of San Luis Potosi,
Mexico and Baylor Col. of Med.
C380 I
1045.27 Milk
lactoferrin
supplementation
enhances early brain development and cognition in postnatal
piglets B. Wang, Y. Chen, Z.Q. Zheng, X. Zhu, Y.J. Shi, D.D.
Tian and F.A. Troy. Sch. of Animal and Vet. Sci., Charles Sturt
Univ., Australia, Xiamen Univ., China, Xiamen Univ. Sch. of
Med., Nestle Res. Ctr. Beijing and Univ. of California Sch. of
Med., Davis.
C381 II
1045.28 The okra skin extract and its cholesterollowering activities — in vitro study K. Mäkynen, S. Ngamukote,
S. Adisakwattana, K. Saligupta, R. Rattanakusumanon,
C. Puttaraksa and C. Kaewsuwan. Chulalongkorn Univ.,
Thailand and Fac. of Allied Hlth. Sci., Chulalongkorn Univ.
C382 I
1045.29 Inhibition of osteoclast actin ring
formation and activation by phloretin through disturbing integrin
αvβ3-PYK2 pathway E-J. Lee, Y-H. Kim and Y-H. Kang.
Hallym Univ., South Korea.
C383 II
1045.30 Astragalin inhibition of oxidative stressinduced airway epithelial fibrosis by blocking autophagy and
mitochondrial dysfunction I-H. Cho, J-H. Gong and Y-H.
Kang. Hallym Univ., South Korea.
C384 I
1045.31 Resveratrol suppresses TH2 cytokine
production linked to MAPK activation in IgE-antigen complexexposed basophilic mast cells S-Y. Han and Y-H. Kang. Hallym
Univ., South Korea.
C385 II
1045.32 Kaempferol
inhibits
endoplasmic
reticulum stress-associated mucus hypersecretion in airway
epithelial cells and ovalbumin-sensitized mice J-H. Gong and
Y-H. Kang. Hallym Univ., South Korea.
C386 I
1045.33 Potent and specific inhibition of VEGF
signalling mediated by slow tight-binding of flavonoids to VEGF
P.A. Kroon, C.W.A. Moyle, A.B. Cerezo, M.S. Winterbone,
P.W. Needs, W.J. Hollands and R.L. Edwards. Inst. of Food
Res., Norwich, U.K.
C387 II
1045.34 Inhibition of digestive enzymes by tea
polyphenols: enzymological and in silico studies S. Glisan,
S. Sae-Tan, K. Grove, N. Yennawar and J. Lambert. Penn
State.
C388 I
1045.35 A grape seed procyanidin extract lowers
serum triglyceride levels via selective modulation of intestinal
FXR-target gene expression and inhibition of enterohepatic
bile acid recirculation R. Hintz, G. Caiozzi and M-L. Ricketts.
Univ. of Nevada, Reno.
TUESDAYNUTRITION/PATHOLOGY
C389 II
1045.36 Analysis of polymethoxyflavones effects
on human colon cancer cells using Raman microscopy H.
Zhang, H. Xiao and L. He. Univ. of Massachusetts Amherst.
C390 I
1045.37 d-δ-Tocotrienol
promotes
the
differentiation of murine MC3T3-E1 preosteoblasts A. Shah,
H. Yeganehjoo, S. Juma, N. DiMarco and H. Mo. Texas
Woman’s Univ.
C391 II
1045.38 Clove
extract
regulates
energy
metabolism in differentiated C2C12 cells A. Tu, T. MossPierce, A. Jiang and P. Ford. McCormick, Hunt Valley, MD.
C392 I
1045.39 Resveratrol compounds are potent
inhibitors of human holocarboxylase synthetase and cause a
lean phenotype in Drosophila melanogaster brummer mutants
E.L. Cordonier, R. Ajam, D. Camara Teixeira, S. Onur, R.
Zbasnik, F. Döring, V.L. Schlegel and J. Zempleni. Univ. of
Nebraska-Lincoln and Univ. of Kiel.
C393 II
1045.40 Ursolic acid, a promising dietary
bioactive compound of anti-obesity Y. Wang and Y. He. Natl.
Res. Council Canada, Charlottetown and Chinese Acad. of
Sci., Kunming.
C394 I
1045.41 The antiatherogenic effects of targeted
epigallocatechin gallate - loaded nanoparticles J. Zhang, s.
Nie and s. Wang. Texas Tech Univ.
C395 II
1045.42 Aplysin administration reduces alcoholic
liver injury by inhibiting nitric oxide production H. Liang and H.
Liang. Med. Col., Qingdao Univ., China.
C396 I
1045.43 Effects of cinnamon metabolites on
glucose utilization and glycolysis T.A. Jiang, T. Moss-Pierce
and Z. Tu. McCormick and Co. Inc., Hunt Valley, MD.
C397 II
1045.44 Phytochemical genistein promotes
pancreatic beta-cell survival and exerts anti-diabetic effect via
GPR30-mediated mechanism A. Wang, D. Liu, J. Luo, K-S.
Suh, W. Moore and H. Alkhalidy. Virginia Tech.
C398 I
1045.45 Modulation of estrogen metabolism by
broccoli: mechanistic investigation of cancer prevention N.
Gaikwad, H. Kucera, D. Olivera and T. Shibamoto. Univ. of
California, Davis.
C399 II
1045.46 Molecular mechanisms of conjugated
linoleic acid (CLA) on muscle metabolism in adult onset
inactivity-induced obese mice Y. Kim, D.J. Good, C-S. Park
and Y. Park. Univ. of Massachusetts, VPI and State Univ. and
KyungHee Univ.
C400 I
1045.47 Purple-fleshed potato, even after
processing, prevents and reverses high-fat diet elevated
colonic-mesenteric fat—systemic inflammation cascade in
pig model S. Radhakrishnan, S.W. Kim, L. Reddivari and
J. Vanamala. Colorado State Univ., Penn State and North
Carolina State Univ.
Pathology
1046.EXTRACELLULAR MATRIX IN PATHOBIOLOGY
Poster
Presentation time: 11:45 am–1:45 pm
B334 1046.1 Granzyme B contributes to extracellular matrix
degradation in UV-treated skin L.G. Parkinson, A. Toro and
D.J. Granville. Univ. of British Columbia.
B335 1046.3 Regulation of versican expression by bacterial
infection is TLR4-dependent but MyD88-independent M.Y.
Chang, M.A. Delaney, A.M. Hajjar, T.N. Wight and C.W.
Frevert. Univ. of Washington and Benaroya Res. Inst. at
Virginia Mason.
B336 1046.4 Matrix
metalloproteinase-19
deficient
fibroblasts display a profibrotic phenotype A. Pardo, P. Jara,
J. Calyeca, Y. Romero, L. Placido, G. Yu, V. Maldonado and
M. Selman. UNAM, Mexico City, Yale Univ. Sch. of Med., Natl.
Inst. of Genomic Med., Mexico City and Natl. Inst. of Resp.
Dis., Mexico City.
B337 1046.5 Role of GSK3 beta and ERK in the human
neutrophil response to fungal beta-glucan C.M. Johnson, A.
Byrd and J. Reichner. Brown Univ./ Rhode Island Hosp.
B338 1046.6 Assessment of NETosis in patients with primary
immunodeficiencies: evidence for a ROS-independent pathway
A.S. Byrd, X.M. O’Brien, C.M. Johnson, K.A. Zarember, E.P.
Sampaio, S.S. Laforce-Nesbitt, J.M. Bliss, P.E. Newburger,
S.M. Holland and J.S. Reichner. Rhode Island Hosp., Women
& Infants Hosp. of Rhode Island, Warren Alpert Med. Sch.,
Brown Univ., NIAID, NIH and Univ. of Massachusetts Med.
Sch.
B339 1046.7 The role of platelet activation in the expression
and function of platelet hyaluronidase-2 S. Albeiroti, K.
Ayasoufi and C. de la Motte. Cleveland State Univ. and
Cleveland Clin. Lerner Res. Inst.
B340 1046.8 The effects of extracorporeal shockwave
therapy on matrix metalloprotease activity in tendinopathy C.M.
Waugh, E.R. Jones, G.P. Riley, H. Langberg, D. Morrissey
and H.R. Screen. Brunel Univ., London, Queen Mary Univ.,
Univ. of East Anglia, U.K. and Univ. of Copenhagen.
B341 1046.9 Versican is a critical extracellular matrix protein
in lung and brain during embryonic development in the mouse
J.M. Snyder, I.M. Washington, M.Y. Chang and C.W. Frevert.
Univ. of Washington and Arizona State Univ.
B342 1046.10 Characterization of force sensing apparatus
in human periodontal ligament fibroblasts E.J. Macarak,
M.J. Braud, W. Wei, K. Giglou and P.S. Howard. Univ. of
Pennsylvania.
1047.CANCER BIOLOGY
Poster
Neoplasia
B343 1047.1 Epithelial-mesenchymal cross talk in cancer
behavior P. Szabo, K. Smetana, B. Dvorankova, M. Kolar
and H. Strnad. First Fac. of Med., Charles Univ., Czech
Republic and Inst. of Molec. Genet. of the ASCR, v.v.i., Prague.
345
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B344 1047.2 CoCl2, chemical inducer of Hif1-alpha, and
CD44 expression in salivary glands malignant neoplasm cell
line D.F. Soave, M.R.N. Celes and A. Ribeiro-Silva. Univ. of
São Paulo, Ribeirão Preto and Fed. Univ. of Goiás, Brazil.
B345 1047.3 Identification of FOXO1 as a major
transcriptional mediator of angiotensin-(1-7) signaling in
tumoral cell lines D.G. Passos-Silva, T. Verano-Braga, A.A.
Peluso, G.M. Etelvino, P. Roepstorff and R.A.S. Santos.
INCT Nanobiofar, Belo Horizonte and Univ. of Southern
Denmark.
B346 1047.4 Upregulation of ADP-ribosylation factor 1
contributes to the enhanced activation of the MAPK ERK1/2 in
prostate cancer cells J.E. Davis, Y. Teng, J. Guo and G. Wu.
Georgia Regents Univ.
B347 1047.5 BMI-1 silencing significantly reduces gene
expression of DNA damage repair markers in human breast
cancer G.G. Silveira, M.R.N. Celes, D.F. Soave, J.P. OliveiraCosta and A. Ribeiro-Silva. Univ. of São Paulo, Ribeirão
Preto and Fed. Univ. of Goiás, Brazil.
B348 1047.6 Cyclin A2 as a regulator of DNA strand
stability P. Gygli, F.P. catacutan, H. Gokozan, T. Schmidt, J.
Stephens, K. Palanichamy and J.J. Otero. The Ohio State
Univ. Col. of Med.
B349 1047.7 Alteration of pro-apoptotic and anti-apoptotic
gene expression in breast cancer cell lines L.M. Edson, D.J.
Hunter and W.B. Coleman. Univ. of North Carolina Sch. of
Med.
B350 1047.8 Loss of tumor necrosis factor superfamily
genes in breast cancer cell lines D.J. Hunter, L.M. Edson and
W.B. Coleman. Univ. of North Carolina Sch. of Med.
B351 1047.9 Whole genome methylation sequencing reveals
distinct impact of differential methylations on gene transcription
in prostate cancer J. Luo, Y.P. Yu, Y. Ding, G.C. Tseng, A.
Michalopoulos and J.B. Nelson. Univ. of Pittsburgh.
B352 1047.10 Examining the carcinogenic potential of
pancreatic inflammation in obese mice with maspin staining A.
Molteni, A. Saeed, A. Glazyrin, V. Pennington, M. Gawlik, A.
Saeed, T. Quinn and B. Herndon. Univ. of Missouri-Kansas
City Sch. of Med and Kansas Univ. Sch. of Med.
B353 1047.11 Effects of 5-azacytidine on the in vitro colony
growth of the MDA-MB 435 cancer cell line J. Hellreich, J.
Gasparek and R. O’Donnell. SUNY Geneseo.
B354 1047.12 Altered expression of epigenetic modulators
involved in cisplatin resistance of ovarian cancer J.Y. Lim, J.Y.
Lee and Y.J. Park. Ewha Womans Univ., South Korea.
B355 1047.13 Identification of expression profiles associated
to oral squamous cell carcinoma development by cDNA
microarrays J.P. Oliveira-Costa, M.P. Gigliola, D.M. Carraro,
F.A. Soares and A. Ribeiro-Silva. Ribeirão Preto Med. Sch.,
Univ. of São Paulo and AC Camargo Cancer Ctr., São Paulo.
B356 1047.14 Expressional profiling of carcinoembryonic
antigen-related microRNAs in human gastric cancer G. Zhang,
H-L. Ye, P. Yao, B. Nong and J. Li. People’s Hosp. of Guangxi
Zhuang Autonomous Reg., Nanning.
B357 1047.15 Is cigarette smoking an independent risk factor
of metastatic disease in prostate cancer? J. McHowat, S.E.
Kispert, J.O. Marentette and J. Powell. Saint Louis Univ.
Sch. of Med.
346
1048.CANCER THERAPY AND PREDICTION
Poster
B358 1048.1 Dissecting the role of IKKβ in tumor-specific
cell death P.M. Fields, A. Beattie, M. Limoge and A. Bakin.
SUNY Geneseo and Roswell Park Cancer Inst.
B359 1048.2 Carcinoembryonic cell adhesion molecule 6
as a therapeutic target for breast cancer T-M. Cheng, Y-R.
Liu, C-C. Chang, H-L. Chu, D-B. Shieh, L-J. Su and Y. Yen.
Col. of Med. and Technol., Taipei, Col. of Med. and Technol.,
Hsinchu, Natl. Cheng Kung Univ., Tainan and Core Facil. for
High Throughput Exptl. Analysis, Taoyuan, Taiwan.
B360 1048.3 Effect of panobinostat (HDACi) alone and in
combination with tamoxifen (PKCi) on glioblastoma cell line
viability G.L. Trivedi and K.E. Benzeroual. A&MS Col. of
Pharm., Long Island Univ.
B361 1048.4 In vitro 3D evaluation of penetrability of SRJ09,
a semisynthetic anticancer agent C.C. Wong, N. Periasamy,
S.R. Sagineedu, S.M. Sidik, S.H. Sumon, R. Phillips, N.H.
Lajis and J. Stanslas. Univ. Putra Malaysia, Univ. of Bradford,
U.K. and Inst. of Biosci., Serdang, Malaysia.
B362 1048.5 MWNTs inhibit breast cancer migration E.
Wailes and N.H. Levi-Polyachenko. Wake Forest Univ.
B363 1048.6 cDNA and lincRNA microarrays: identification
of expression patterns related to metastatization in oral
squamous cell carcinoma J.P. Oliveira-Costa, M.P. Gigliola,
M.P. Macedo, D.M. Carraro and F.A. Soares. AC Camargo
Cancer Ctr., São Paulo.
B364 1048.7 Antiangiogenic therapies and aged-associated
changes in the prostate: a comparison between the prostate of
aging mice (FVB) and TRAMP mice V. Cagnon, F. Montico,
L.A. Kido and A.C. Hetzl. Univ. of Campinas, Brazil.
B365 1048.8 Goniothalamin and Celocoxib therapies on the
preneoplastic and neoplastic prostatic lesions in the transgenic
adenocarcinoma of the mouse prostate model (TRAMP)
V. Cagnon, L.A. kido, F. Montico, C.S. Dall Pozzo, J.E.
Carvalho, D.B. Costa and R. Pilli. Univ. of Campinas, Brazil.
B366 1048.9 Epigenetic regulation of CFTR during cancer
development and implications in cancer treatment W. Huang,
K.L. Fok, X.H. Jiang and H.C. Chan. The Chinese Univ. of
Hong Kong.
B367 1048.10 LC-MS/MS method development for the
measurement of 15 estrogens and estrogen metabolites in
human plasma and serum D. Wambua, N.E. Craft and R.G.
Ziegler. Craft Technols. Inc., Wilson, NC and NCI, NIH.
B368 1048.11 Metallothioneins are potential prognostic
biomarkers in breast cancer patients D.N. Malepati and L. S.
Yogi Vemana Univ., India and Sri Venkateswara Univ., India.
B369 1048.12 Immunoexpression of the human kallikrein-10
in surgically removed human pituitary tumors F. Rotondo,
A. Di Ieva, K. Kovacs, L.V. Syro, M.D. Cusimano and G.
Yousef. St. Michael’s Hosp., Toronto and Hosp. Pablo Tobon
Uribe, Medellin, Colombia.
B370 1048.13 Screening of some natural products and
nanoparticles for their anti-breast cancer activities C.T.
Ahweyevu and M.A. Taha. Albany State Univ.
B371 1048.14 Methods for rapid extraction of high-quality RNA
from FFPE cancer tissue M. Hoover, M. Brown, A. Maawy, R.
Hoffman, M. Bouvet, R. Doebler and J.A. Kelber. California
State Univ., Northridge, Claremont BioSolutions, Upland, CA,
UCSD Sch. of Med. and AntiCancer Inc., San Diego.
TUESDAYPATHOLOGY
B372 1048.15 The template tissue arrayer — a simplified, low
cost tissue microarray instrument S.M. Hewitt, J. Morris and
K. Ylaya. NCI, NIH.
B373 1048.16 Immunoblotting analysis of formalin-fixed and
paraffin-embedded malignant tumor samples M.R. Celes, D.F.
Soave, A.C.S. Freitas, S.G. Ramos and A. Ribeiro-Silva.
Univ. of São Paulo and Fed. Univ. of Goiás, Brazil.
B374 1048.18 Ameloblastoma driver mutations revealed
by next-generation sequencing of formalin-fixed paraffinembedded specimens J.R. Pollack, A.C. McClary, R.T.
Sweeney, J. Biscocho, B.R. Myers, L. Neahring, K.A. Kwei,
K. Qu, X. Gong, T. Ng, C.D. Jones, S. Varma, J.I. Odegaard,
B. Rubin, M.L. Troxell, R.J. Pelham, J.L. Zehnder, P.A.
Beachy and R.B. West. Stanford Univ., Genomic Hlth.,
Redwood City, Univ. of British Columbia, Cleveland Clin. and
Oregon Hlth. & Sci. Univ.
B375 1048.19 The effect of CBD, CBG and a combination of
CBD plus CBG on Haccat human skin carcinoma cells F. Javid
and S. Afshinjavid. Univ. of Huddersfield, U.K.
B376 1048.20 Pre-operative
training
induced
histomorphometric changes and function on pelvic floor muscle
in patients undergoing radical prostatectomy R. Ramirez Velez,
Á. Ocampo-Trujillo and C.A. Muñoz. Univ. Santo Tomas, Ctr.
Med. Imbanaco, Cali and Univ. del Valle, Colombia.
1049.LUNG CANCER
Poster
Pulmonary Pathobiology
Neoplasia
B377 1049.1 An upregulated long noncoding RNA RP3337D23.3 in lung adenocarcinoma in never-smokers promotes
metastasis R. Yin, M. Qiu, F. Jiang and L. Xu. Nanjing Med.
Univ. Affil. Cancer Hosp., China.
B378 1049.2 Role of WWOX and NF-κB in lung cancer
progression N-S. Chang. Natl. Cheng Kung Univ., Taiwan.
B379 1049.3 Glypican-5 regulates lung cancer cell
metastasis through Wnt signaling pathway L. Xu, R. Yin, F.
Jiang and X. Yang. Nanjing Med. Univ. Affil. Cancer Hosp.
B380 1049.4 Angiotensin receptor blockers are not
carcinogenic in rodents A.F. De Felice, W.T. Link and P. Gatti.
FDA, Silver Spring, MD.
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1050.BIOINFORMATICS, BIOBANKING AND IMAGING
Poster
Biomarkers and Biobanking
B381 1050.1 Evaluation of tissue section cryostorage
on immunohistochemistry L.I. Estrada, A.C. Amaral, E.L.
Giannaris, N.C. Heyworth, F. Mortazavi, L.B. Ngwenya, D.E.
Roberts, A.A. Robinson, R.J. Killiany and D.L. Rosene.
Boston Univ. Sch. of Med.
B382 1050.2 New en bloc staining technique improve
tissue contrast and electrical conductivity C. Negron-Morales,
I.I. Torres-Vazquez, J.L. Serrano-Velez, R.D. Powell and
E. Rosa-Molinar. Univ. of Puerto Rico-Rio Piedras and
Nanoprobes Inc., Yaphank, NY.
B383 1050.3 In vivo demonstration of okadaic acid
internalization in glutamatergic spinal motor neurons I.I.
Torres-Vazquez, C.A. Torrech-Santos, J.L. Serrano-Velez,
K. Rein and E. Rosa-Molinar. Univ. of Puerto Rico, Rio
Piedras Campus and Florida Intl. Univ.
B384 1050.4 Molecular histology of fixed tissues using
imaging mass spectrometry D.S. Cornett. Bruker Corp.,
Billerica, MA.
B385 1050.5 Image cytometry for 2D and 3D quantification
in microscopic images C. Van Noorden. Acad. Med. Ctr.,
Amsterdam.
B386 1050.6 Laminitis-specific microRNAs in equine plasma
M-C. Kim, S-W. Lee, F-J. Cui, D-Y. Ryu and Y. Kim. Col. of
Vet. Med., Seoul Natl. Univ.
B387 1050.7 Profiling of plasma microRNA expression in
horses (Equus caballus) using next-generation sequencing
D-Y. Ryu, Y-b. Kim, M-C. Kim and S. Lee. Seoul Natl. Univ.
B388 1050.8 Evidence for mitotic recombination in the subtelomeric regions of the Plasmodium falciparum genome,
with implications for malaria virulence S.S. Singhakul, M.J.
Manary and E.A. Winzeler. UCSD.
B389 1050.9 Direct detection of green fluorescent protein in
histological preparations of recombinant vaccinia virus in mice
C. Lyons. NIAID, NIH, Frederick.
B390 1050.10 Histomorphologic characterization of human
tissues stained with selected plant-based dyes R.B. Bassey, Y.
Hu, J. Tomaszewski, P. Nickerson, J. Holmes, L.A. Colón,
A. Osinubi and A. Oremosu. Univ. of Uyo, Nigeria, Univ. at
Buffalo and Univ. of Lagos.
B391 1050.11 Superficial neuromasts as proprioceptive
receptors in poeciliid fish N. Martinez-Rivera, J.L. SerranoVelez, I.I. Torres-Vazquez and E. Rosa-Molinar. Univ. of
Puerto Rico- Rio Piedras campus.
LAST DAY TO
VISIT EXHIBITS
Tuesday, April 29
9:00 AM – 4:00 PM
347
T
U
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PHARMACOLOGYTUESDAY
Pharmacology and Experimental Therapeutics
1051.CARDIOVASCULAR DISEASE – DIABETES
Poster
B157 1051.1 Arginase 1 regulates SIRT1 activity and
endothelial senescence in diabetes H.A. Toque, A. Bhatta,
L. Yao, R.B. Caldwell and R.W. Caldwell. Georgia Regents
Univ.
B158 1051.2 microRNA-34a
mediates
impaired
angiogenesis in diabetes: role of SIRT1 and metformin G.
Arunachalam, S.M. Samuel, S. Ghosh, C.R. Triggle and H.
Ding. Weill Cornell Med. Col., Doha.
B159 1051.3 Sodium 4-phenylbutyrate reverses glucose
deprivation-induced endoplasmic reticulum stress and death
signal in cultured mouse microvascular endothelial cells S.M.
Samuel, G. Arunachalam, S. Ghosh, M.M. Emara, H. Ding
and C.R. Triggle. Weill Cornell Med. Col. in Qatar and Qatar
Biomed. Res. Inst., Doha.
B160 1051.4 DPP-4
inhibitor
linagliptin
restores
endothelium-dependent relaxation in small mesenteric artery
from type-1 diabetic rats S. Salheen, O. Woodman, A. Mather,
U. Panchapakesan and C. Pollock. Hlth. Innovations Res.
Inst. RMIT Univ. and Kolling Inst., St. Leonards, Australia.
B161 1051.5 Reversal of diabetic stem-cell mobilopathy by
angiotensin-(1-7) via rho-kinase downregulation G. Vasam,
M.K. Raizada and Y.P. Jarajapu. North Dakota State Univ.
and Univ. of Florida.
B162 1051.6 Protein and gene expression of angiotensin II
receptors (AT1 and AT2) in aorta of diabetic and hypertensive
rats R. Romero, A.A. Reséndiz-Albor, J.E. Rodriguez, F.
Sanchez-Muñoz, E. Hong and S. Villafaña. Sch. of Med.,
Natl. Polytech Inst., Natl. Inst. of Cardiol. and CINVESTAV
SUR, Mexico City.
B163 1051.7 Expression of the orphan receptors GPR22,
GPR162, GPR27 and GPR17 in cardiovascular tissues of
diabetic rats A. Ruiz H, E. Hong, F. Sanchez-Muñoz and S.
Villafaña. Sch. of Med., Natl. Polytech Inst., CINVESTAV SUR
and Natl. Inst. of Cardiol., Mexico City.
B164 1051.8 Sexual dimorphism in aortic endothelial
function of Zucker diabetic fatty rats: possible involvement of
superoxide production X. Han, S. Shaligram, L. Anderson
and R. Rahimian. Univ. of Pacific Sch. of Pharm., Stockton
and Univ. of Pacific Sch. of Dent., San Francisco.
B165 1051.9 Evidence that chronic administration of
17β-estradiol decreased the vasopressor responses in
streptozotocin-diabetic female rats D. Centurion, S.J. AcostaCota and A.C. Sanchez-Lopez. CINVESTAV, Mexico City.
B166 1051.10 Maternal vasculature changes produced
by experimental gestational diabetes mellitus by obesity C.
Tufiño, P. Rosas and R. Bobadilla and Natl. Polytech Inst.,
Mexico City.
B167 1051.11 Acute
Tocomin
treatment
improves
endothelium-dependent relaxation in aortae from diabetic and
western diet fed rats. S.F. Ali, J.C. Nguyen, T.A. Jenkins and
O.L. Woodman. Sch. of Med. Sci., RMIT Univ., Australia.
348
B168 1051.12 Continuous glucose and food intake
monitoring in the male ZDSD rat: comparison of normal and
high fat diets C.V. Jackson, R.G. Peterson, D. Compton,
E. Ulman, S. Tiesma and R. Brockway. PreClinOmics Inc.,
Indianapolis,Res. Diets Inc., New Brunswick and Data Sci.
Intl., St. Paul.
B169 1051.13 Hyperhomocysteinemia aggravates endothelial
dysfunction via EDHF impairment in resistant arteries of db/db
mice Z. Cheng, X. Jiang, P. Fang, X. Yang and H. Wang.
Temple Univ.
B170 1051.14 Simvastatin, atorvastatin, and pravastatin are
equally effective in improving the hemodynamic status of type
1 diabetic rats J. Quidgley, N. Cruz, G. Melendez and M.J.
Crespo. Univ. of Puerto Rico-Sch. of Med.
B171 1051.15 Sex-based alteration of relative importance of
EDRFs in modulating vascular reactivity in Zucker diabetic fatty
rats S. Shaligram, X. Han, R. Zhang, L. Anderson and R.
Rahimian. Sch. of Pharm., Univ. of Pacific and Sch. of Dent.,
Univ. of Pacific.
B172 1051.16 Increased basal and adenosine-mediated
coronary flow in ex vivo hearts from type I diabetic mice H.
Labazi, X. Zhou, B. Teng and S.J. Mustafa. West Virginia
Univ.
B173 1051.17 Low molecular weight fucoidan against diabetic
nephropathy H. Zhou. Peking Univ.
B174 1051.18 Expression and localization of alpha-1
adrenergic receptors in aorta of diabetic Wistar Kyoto and
spontaneously hypertensive rats J.E. Rodriguez, A.A.
Reséndiz-Albor, E.E. Rosales-Cruz, E.E. Hong and S.
Villafaña. Sch. of Med., Natl. Polytech Inst., Natl. Sch. of Biol.
Sci. and CINVESTAV, Mexico City.
1052.GI CANCER
Poster
B175 1052.1 Adaptive
cytoprotection
and
cancer
chemoprotection by sulforaphane against various stresses:
role of nrf2-keap1 dependent and independent pathways A.
Yanaka. Univ. of Tskukuba.
B176 1052.2 Biomarkers for Western diet accentuated
cellular damage in benzo(a)pyrene-induced colon cancer K.L.
Harris, S.R. Pulliam, M.S. Niaz, E.U. Okoro, Z. Guo, M.K.
Washington, S.E. Adunyah and A. Ramesh. Meharry Med.
Col. and Vanderbilt-Ingram Cancer Ctr.
B177 1052.3 Mitophagy-mediated NLRP3 inflammasome
inhibition by andrographolide contributes to the prevention of
colitis-associated cancer Y. Sun, W. Guo and Q. Xu. Nanjing
Univ., China.
B178 1052.4 Suppression of colorectal cancer subcutaneous
xenograft and experimental lung metastasis using nanoparticlemediated drug delivery to tumor neovasculature C. Wang, M.
Zhao, Y-R. Liu, X. Luan, Y-Y. Guan, Q. Lu, H-Z. Chen and C.
Fang. Shanghai Jiao Tong Univ. Sch. of Med. and Shanghai
Inst. of Hlth. Sci. and Hlth. Sch. Attached to Shanghai Jiao
Tong Univ. Sch. of Med.
TUESDAYPHARMACOLOGY
B179 1052.5 Role of substance P and CGRP in gastric
MALT lymphoma induced by Helicobacter heilmannii infection
M. Nakamura, H. Matsui, T. Takahashi and K. Tsuchimoto.
Kitasato Univ., Japan.
B180 1052.6 Altered irinotecan pharmacokinetics in dietinduced obesity P. Shah, A. Gandhi and R. Ghose. Univ. of
Houston.
B181 1052.7 Hypoxia inducible factor-1α inhibition by
protopophyrin IX through miR-199a-5p upregulation in
mesenchymal-typed hepatocellular carcinoma J.M. Lee, W.H.
Lee and S.G. Kim. Col. of Pharm., Seoul Natl. Univ.
B182 1052.8 Sevoflurane enhances proliferation of human
colon cancer HCT116 cells via adenosine triphosphatesensitive potassium channels Y. Kawaraguchi, H. Sugimoto,
Y. Nomura, H. Furuya and M. Kawaguchi. Nara Med. Univ.,
Japan.
1053.CLINICAL PHARMACOLOGY/DRUG DELIVERY
Poster
B183 1053.1 Academia-industry alliances for biomedical
innovation — what can we do better? E.M. Seymour. Univ. of
Michigan.
B184 1053.2 Bioequivalence of alendronate and vitamin
D3 in an alendronate/vitamin D3 combination tablet G-C. Yeh,
K. Brown, R. Mols, E. Woolf, H. Wright, L. Maganti and S.
Zajic. Taipei Med. Univ. Hosp. and Merck & Co. Inc.
B185 1053.3 Investigation of sorbitan niosomal gel for
sustained release ocular delivery of piroxicam B.K. Abdul
Rasool, O.S. Alsawad, H.A. Lootah, I.M. Abusharbain and
H.A. Abu-Alhaj. Dubai Pharm. Col. and Univ. of Basrah, Iraq.
B186 1053.4 A corneal penetrating drug delivery system
based on elastin-like polypeptide G.L. Bidwell, H. Liu, G.G.
Robinson, M. Marquart and E.M. George. Univ. of Mississippi
Med. Ctr.
B187 1053.5 Spatiotemporally controlled delivery of
biomolecules D.P. Morales, G.B. Braun, A. Pallaoro, R.
Chen, X. Huang, J.A. Zasadzinski and N.O. Reich. Univ. of
California, Santa Barbara, Sanford-Burnham Med. Res. Inst.
and Univ. of Minnesota, Minneapolis.
B188 1053.6 Characterizing the abuse potential of
loperamide via physiologically-based pharmacokinetic/
pharmacodynamic modeling and simulation G.R. Ainslie,
E.D. Kharasch, G.M. Pollack and M.F. Paine. Univ. of North
Carolina at Chapel Hill, Washington State Univ., Washington
Univ. in St. Louis and Univ. of North Carolina.
B189 1053.7 A survey of the most common methods of
group randomization and distribution in pre-clinical in vivo
studies J.L. Kumer and E.M. Ibsen. Studylog Systs. Inc.,
South San Francisco.
B190 1053.8 An in silico pharmacokinetic/pharmacodynamic
model of agonist self-administration behavior in rats A.C.
Ross, V.L. Tsibulsky and A.B. Norman. Univ. of Cincinnati.
1054.CHEMICAL BIOLOGY AND EXPERIMENTAL
THERAPEUTICS
Poster
B191 1054.1 A platform-based approach for peptide drug
discovery: generating probes to understand and treat itch J.R.
Doyle, K. Kumar, X. Dong and A.S. Kopin. Tufts Med. Ctr.,
Tufts Univ. and Johns Hopkins Univ. Sch. of Med.
B192 1054.2 Evaluation of functional activity and
aggregation properties of hemopressin S.K. Nayak, B. Song,
P. Kibler, A.S. Adem, A. Endsley, K. Jambunathan and A.K.
Galande. SRI Intl., Harrisonburg, VA.
B193 1054.3 Withdrawn.
B194 1054.4 Protease-activated peptide toxins for selective
nanoparticle therapeutics A.P. Jallouk, R.U. Palekar, P.H.
Schlesinger, H. Pan and S.A. Wickline. Washington Univ. in
St. Louis.
B195 1054.5 Antithrombotic activity of new 1-ethylxanthine
cyclohexylammonium salt A.V. Samorodov, F.K. Kamilov,
G.A. Timirkhanova, A.I. Samorodova, F.A. Khaliullin and
D.Z. Murataev. Bashkirian State Med. Univ., Russia.
B196 1054.6 New antiplatelet and vasorelaxant agents
based on the pyridazinone moiety P. Besada, T. Costas, M.C.
Costas-Lago, N. Vila, M. Yañez, L. Acevedo, E. Cano and
C. Teran. Univ. of Vigo and Univ. of Santiago de Compostela,
Spain.
B197 1054.7 The impact of immune modulators from the
group of substituted thiadiazines on the severity of stress
reaction A.P. Sarapultsev, O.N. Chupakhin, P.A. Sarapultsev,
E.A. Mukhlynina, G.P. Sarapultsev, S.U. Medvedeva and
I.G. Danilova. Inst. of Immunol. and Physiol., Ural Branch of
RAS, Ekaterinburg, IJ Postovsky Inst. of Organic Synthesis,
Ural Branch of RAS and Ural Fed. Univ. named after the first
President of Russia B. N. Yeltsin.
B198 1054.8 Epigenetic regulation of IL-6 by proinflammatory cytokines in rheumatoid arthritis synovial
fibroblasts: role of HDAC inhibitors S. Riegsecker, W.
Wingerter, A.K. Singh, P. Bhansali, L.M.V. Tillekeratne and
S. Ahmed. Univ. of Toledo Col. of Pharm. and Pharmaceut.
Sci.
B199 1054.9 Modulating myofibroblast transition in systemic
sclerosis through inhibition of Rho/MRTF regulated transcription
A.J. Haak, P-S. Tsou, D. Fox, D. Khanna, S. Larsen and R.
Neubig. Univ. of Michigan and Michigan State Univ.
B200 1054.10 Discovery and characterization of the first
cellularly active, non-covalent inhibitor of a regulator of G
protein signaling protein (RGS protein) D.I. Mackie, C.R.
Bodle, M.P. Hayes and D.L. Roman. Univ. of Iowa.
B201 1054.11 Efficacy of a novel integrin-targeted anti-c-Myc
nanotherapy against multiple myeloma in mice D. Soodgupta,
D. Pan, G. Hu, A. Sen Pan, X. Yang, E.V. Prochownik, G.M.
Lanza and M.H. Tomasson. Washington Univ. Sch. of Med.,
Univ. of Illinois at Urbana-Champaign and Univ. of Pittsburg
Sch. of Med.
349
T
U
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PHARMACOLOGYTUESDAY
1055.SIGNAL TRANSDUCTION – KINASES/
PHOSPHATASES
Poster
B202 1055.1 PKD inhibitor treatment results in increased
PKD activation loop phosphorylation M.T. Kunkel and A.C.
Newton. UCSD.
B203 1055.2 Prevalence of inactivating protein kinase
C mutations in human cancers C.E. Antal, E. Kang, N.L.
Stephenson, E.W. Trotter, T. Hunter, J. Brognard and A.C.
Newton. UCSD, Univ. of Manchester and Salk Inst.
B204 1055.3 Examination of ubiquitination and SUMOlyation
of GRK4γ J.H. Nguyen, B. Andresen, T. Liu, R.T. Alkaddumi,
C.W. Adams, J.W. Liu and S.H. Chiang. Western Univ. of
Hlth. Sci., CA, Univ. of Missouri-Columbia, Keck Grad. Inst.,
Claremont, CA and Univ. of California, Irvine.
B205 1055.4 Differential modulation of p-4EBP1, p-ERK and
cyclin D1 by amuvatinib/erlotinib treatment in prostate cancer
cells R.D. Canatsey, W.L. Cai, N.J. Mastrandrea, J.M. Gard,
R.B. Nagle, T.J. Monks and S.S. Lau. Univ. of Arizona.
B206 1055.5 TPA-induced invasion of HT29 cells are
mediated through ROS production and AMPK deactivation S.
Banskota and J-A. Kim. Yeungnam Univ., South Korea.
B207 1055.6 Birc6 drives drug resistance and cell survival in
chronic myeloid leukemia D. Okumu, M. Levine, L. Jones, R.
Zhang and L. Graves. Univ. of North Carolina at Chapel Hill.
B208 1055.7 Fyn kinase regulates microglial neuroinflammatory responses in cell culture and animal models of
Parkinson’s disease N. Panicker, H. Jin, H. Saminathan,
K. Kanthasamy, V. Anantram, A. Kanthasamy and A.
Kanthasamy. Iowa State Univ. and Rice Univ.
1056.IMMUNOMODULATION
Poster
B209 1056.1 Evaluation of anti-inflammatory effect of
analogs of L-carnitine in a model of chronic inflammation in
vivo B. Mendoza-Rivera, J. Reyes-Esparza, R. De La Cruz
Cordero and L. Rodriguez-Fragoso. Fac. of Pharm., UAEM,
Cuernavaca and Nucitec SA de CV, Querétaro, Mexico.
B210 1056.2 Methyl salicylate lactoside inhibits inflammatory
response on fibroblast-like synoviocytes and collagen-induced
arthritis by inhibiting NF-κB activation T. Zhang, W. Xin, C.
Huang and G. Du. Peking Union Med. Col.
B211 1056.3 Anti-inflammatory effect of IMMP in a metabolic
syndrome model A. Gomez-Solis, J. Reyes-Esparza, F.
Garcia-Vazquez, E. Alvarez-Ayala, E. Farfan-Morales and L.
Rodriguez-Fragoso. Univ. of Morelos, Cuernavaca and Natl.
Inst. of Pediat., Mexico City.
B212 1056.4 A study of the effects of 25wssw on antiendotoxemia S.F. Yun, Y.D. Ya, R.G. Yao, Z.Z. Teng, L. Jie,
W.S. Hua and Z. Qin. Tibet Inst. for Nationalities.
B213 1056.5 The inhibitory effect of sinigrin on the production
of inflammatory mediators induced by lipopolysaccharide in
RAW 264.7 macrophages H. Lee, C. Lee, J. Kim and S. Pyo.
Sungkyunkwan Univ., South Korea.
350
B214 1056.6 TLR4-p38 pathway as a mechanism of APOEmodulated neuroinflammation in Alzheimer disease M.J. LaDu,
S. Wohlgenant, L.J. Van Eldik and L.M. Tai. Univ. of Illionis at
Chicago and Univ. of Kentucky.
B215 1056.7 Pentadecapeptide BPC 157 and anaphylactoid
reaction in rats and mice after intravenous dextran and white
egg administration B. Duplancic, V. Stambolija, J. Katancic
Holjevac, M. Zemba, I. Balenovic, I.D. Drmic, J. Suran, B.
Radic, M. Filipovic, A. Boban Blagaic, L. Brcic, D. Kolenc,
S. Seiwerth, P. Sikiric and Z. Grabarevic. Med. Fac., Univ. of
Zagreb and Fac. of Vet. Med., Univ. of Zagreb, Croatia.
B216 1056.8 Iron chelating agents lead to the formation of
neutrophil extracellular traps and subsequent entrapment of
Staphylocccus aureus L. Völlger, K. Akong, C. Dewitz, Y.
Wang, H.Y. Naim, V. Nizet and M. von Köckritz-Blickwede.
Univ. of Vet. Med. Hannover, UCSD and Penn State.
B217 1056.9 In vivo immunomodulatory effect of S22-Gda
Y. Jang, J. Kim, C. Lee and S. Pyo. Sungkyunkwan Univ.,
South Korea.
1057.ION CHANNELS IN VASCULAR
PHARMACOLOGY
Poster
B218 1057.1 Vasorelaxant response of coronary arteries
to capsaicin and effect of angiotensin II Q. Yang, S-H. Pun
and C-M. Yu. The Chinese Univ. of Hong Kong and TEDA Intl.
Cardiovasc. Hosp., Med. Col., Nankai Univ., China.
B219 1057.2 Arachidonic acid induced calcium signaling at
acidic pH N.K. Moss, B. Hou, R.S. Young, A.F. Bruns, L.A.
Wilson and D.J. Beech. Univ. of Leeds Sch. of Med.
B220 1057.3 Significance of store operated calcium entry
in human abdominal aortic aneurysm vascular smooth muscle
cells M.A. Bailey, R. Young, B. Rode, R. Foster, J. Li and
D.J. Beech. Univ. of Leeds Sch. of Med. and Univ. of Leeds
Sch. of Chem.
B221 1057.4 Resistance of store-operated calcium entry to
tumour microenvironment conditions and enhanced potency of
Synta66 in colorectal adenocarcinoma cells H.L. Appleby, H.
Gaunt, S. Jansz, A. Hyman, O. Stokes, R. Young, R. Foster
and D.J. Beech. Univ. of Leeds Sch. of Med. and Univ. of
Leeds Sch. of Chem.
B222 1057.5 Vascular endothelial growth factor A evokes
distinct calcium entry by promoting surface accumulation of
Orai3 A. Bruns, J. Li, B. Hou, S. Turnover, N.K. Moss, L.
Mckeown, R. Foster and D.J. Beech. Univ. of Leeds Sch. of
Med., Univ. of Leeds Sch. of Food Sci. and Nutr. and Univ. of
Leeds Sch. of Chem.
B223 1057.6 Positive KCa channel gating modulators with
selectivity for KCa3.1 B.M. Brown, N. Coleman, A. OlivánViguera, R. Köhler and H. Wulff. Univ. of California, Davis
and Univ. H. Miguel Servet, Spain.
B224 1057.7 PSD95 scaffolding of the Shaker-type K+
channel enables PKA-dependent phosphorylation and
vasodilation of cerebral arteries C.L. Moore, P.L. Nelson, N.K.
Parelkar, H.M. Hanvey, N.J. Rusch and S.W. Rhee. Univ. of
Arkansas for Med. Sci. and Univ. of Kansas Med. Ctr.
B225 1057.8 Cooperative gating and sensitivity of TRPV4
channels are regulated by distinct factors S.K. Sonkusare, N.
Villalba, K. Freeman, A.D. Bonev and M.T. Nelson. Univ. of
Vermont.
TUESDAYPHARMACOLOGY
B226 1057.9 Impact of TRPC channels on body weight B.
Rode, N.Y. Yuldasheva, S.B. Wheatcroft, J.F. Ainscough
and D.J. Beech. Univ. of Leeds Sch. of Med. and Univ. of
Leeds Fac. of Med. and Hlth.
B227 1057.10 The β3 subunit: a key regulator of vascular
calcium channel expression A.K. Srivastava, L. Song, S.V.
Kharade, T.W. Fletcher, S.W. Rhee and N.J. Rusch. Univ. of
Arkansas for Med. Sci.
B228 1057.11 Mode and site of interaction of the novel
antiplatelet drug ticagrelor at the recombinant human P2Y12
receptor I. von Kügelgen, D.A. Lutz, J. Straßburger, Y. Baqi,
C.E. Müller and K. Hoffmann. Univ. of Bonn.
B229 1057.12 Pharmacological dissection reveals functional
roles for KCNQ channel subtypes in human urinary bladder
smooth muscle contractility A. Provence, E. Rovner and G.V.
Petkov. South Carolina Col. of Pharm. and Med. Univ. of South
Carolina.
1058.KNOWLEDGE OBJECTIVES IN
PHARMACOLOGY
Poster
B230 1058.1 Technical and knowledge-based outcomes
following a one-week high school research program in
toxicology and environmental health sciences G.L. Guo, L.M.
Aleksunes, J.E. Moscovitz, A. Venosa, A. Gow and D.L.
Laskin. Rutgers Univ., Envrn. and Occup. Hlth. Sci. Inst. and
Joint Grad. Prog. in Toxicol., Piscataway.
B231 1058.2 Construction of a common medication list
for use in undergraduate and graduate nursing curricula:
bivariate organization, pedagogical integration, and iterative
redevelopment P.J.M. Murphy. Seattle Univ. Col. of Nursing.
B232 1058.3 Self-assessment of research competencies
during a summer undergraduate research fellowship in
pharmacology and toxicology L.M. Aleksunes, E. Caswell,
J.E. Gutierrez, L.E. Liang and D.L. Laskin. Rutgers Univ.,
Piscataway.
B233 1058.4 Impact of lecturetools on student engagement
and learning H. Swanson, R. Hadley and M. Piascik. Univ. of
Kentucky.
B234 1058.5 FishPharm: zebrafish in pharmacology
education and research K. Chatti. Dr. Reddy’s Inst. of Life Sci.,
Hyderabad.
1059.NEUROTRANSMITTER RECEPTORS – GABA,
NACH AND 5-HT
Poster
B235 1059.1 Comparing the high affinity benzodiazepine
binding site with the homologous “CGS 9895” site in
GABA-A receptors R. Puthenkalam, Z. Varagic, A. Dereky,
C. Suwattanasophon, I. Sarto-Jackson, P. Scholze, W.
Sieghart and M. Ernst. Med. Univ. Vienna and Konrad Lorenz
Inst. for Evol. and Cognition Res., Altenberg, Austria.
B236 1059.2 Symmetry considerations provide a new
novel open channel blocker of GABA-A receptors E. Sigel,
M. Pangerl, V. Carta, R. Baur and D. Trauner. Univ. of Bern,
Switzerland and Ludwig Maximilians Univ. Munich.
B237 1059.3 Novel GABAA-rho1 interactions with acid
sensing ion channel ligands H. Snell and E. Gonzales. Univ.
of North Texas Hlth. Sci. Ctr., Weatherford, Inst. for Aging and
Alzheimer’s Dis. Res., Fort Worth and Cardiac Res. Inst., Fort
Worth.
B238 1059.4 GABA is an inhibitory neurotransmitter in
ganglia of the bivalve mollusc, Crassostrea virginica S.
Mathieu, D. Sylvain, F. Walden, E.J. Catapane and M.A.
Carroll. Medgar Evers Col., Brooklyn.
B239 1059.5 Presence of inhibitory GABA receptors on
serotonin neurons in the bivalve mollusc Crassostrea virginica
C. Welsh, A.E. Saunders, M.A. Carroll and E.J. Catapane.
Medgar Evers Col., Brooklyn.
B240 1059.6 A translational
approach
to
nicotine
dependence: interrogating the Neuregulin-ErbB4 pathway in
mouse and man J. Turner. Univ. of South Carolina.
B241 1059.7 Novel nAChRs modulators for treating
CNS disorders: discovery of AChBP cooperative ligands
K. Kaczanowska, M. Harel, M. Finn and P. Taylor. UCSD,
Weizmann Inst. of Sci., Rehovot and Georgia Tech.
B242 1059.8 Derivatives of 1,2,3-triazole lead found to be
selective and potent agonists at the α7 nicotinic acetylcholine
receptor B. Chen, K. Arunrungvichian, P. Taylor, O.
Vajragupta, V. Fokin, J. Yamauchi and A. Nemecz. UCSD
Skaggs Sch. of Pharm. and Pharmaceut. Sci., Ctr. of Excellence
for Innovation in Drug Design and Discovery, Bangkok and The
Scripps Res. Inst.
B243 1059.9 Alkaloid-dependent fetal muscle-type nicotinic
acetylcholine receptor desensitization B.T. Green, S.T. Lee
and K.D. Welch. Poisonous Plant Res. Lab., Logan, UT.
B244 1059.10 New analogs of 3-pyridyl ether as potential
new ligands with high affinity and efficacy at selective nAChRs
A.E. Ogunjirin, J. Fortunak, L.L. Brown, Y. Xiao and M.I.
Davila-Garcia. Gallaudet Univ., Howard Univ., Univ. of Virgin
Islands and Georgetown Univ.
B245 1059.11 Mechanisms underlying behavioral tolerance
following repeated 5-HT2CR agonist administration in vivo
D.A. Cooper, B.D. Davis-Reyes, M.J. Bubar and K.A.
Cunningham. Univ. of Texas Med. Branch.
B246 1059.12 Modulatory effects of 5-HT2A and AMPA
receptors on in vivo serotonin levels in two key areas of the
brain related to depression Z. Zhou, P.G. Chan and J.A.
Uchizono. Univ. of the Pacific and Western Univ. of Hlth. Sci.
B247 1059.13 Development of novel serotonin 7-targeting
compounds based on the 2-dimethylaminotetralin scaffold C.
Canal, D. Felsing, W. Zhu, Y. Liu, T. Cordova-Sintjago and
R. Booth. Northeastern Univ. and Univ. of Florida.
1060.OCULAR PHARMACOLOGY/TOXICOLOGY
Poster
B249 1060.2 Interaction between hydrogen sulfide and
nitric oxide in isolated bovine retina M. Kulkarni Chitnis, R.
Belford, J. Robinson, L. Mitchell, Y.F. Njie-Mbye, C. Opere
and S. Ohia. Texas Southern Univ. and Creighton Univ.
351
T
U
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PHARMACOLOGYTUESDAY
B250 1060.3 Involvement of KATP channels in hydrogen
sulfide-induced increase in aqueous humor outflow J.D.
Robinson, C. Ezeudu, L. Mitchell, M. Chitnis, C. Opere, S.E.
Ohia and Y.F. Njie-Mbye. Texas Southern Univ. and Creighton
Univ.
B251 1060.4 Comparative
pharmacological
actions
of
N-acetylcysteine
and
L-cysteine
on
excitatory
neurotransmission in bovine isolated retina C.A. Opere, P.
Bankhele, A. Salvi, J. Jamil, D. Munt, Y.F. Njie-Mbye, M.
Chitnis and S. Ohia. Creighton Univ. and Texas Southern
Univ. Col. of Pharm. & Hlth. Sci.
B252 1060.5 Assessment of drug-induced changes in visual
processing using the optomotor response in rodents C. Hsu,
K. Tse and K. Cannon. Pfizer Inc., Groton, CT and Univ. of
Liverpool Wolfson Ctr. for Personalized Med.
1061.PAIN II
Poster
B254 1061.2 Hyperbaric oxygen suppresses paclitaxelinduced cold allodynia in rats Y. Zhang, J.T. Nelson, D.Y.
Shirachi and R.M. Quock. Washington State Univ. and Univ.
of the Pacific.
B255 1061.3 BPC 157 antagonized the general anesthetic
potency of thiopental and reduced prolongation of anesthesia
time induced by L-NAME/thiopental combination M. Zemba, A.
Zemba Cilic, I. Balenovic, M. Cilic, B. Radic, J. Suran, I.D.
Drmic, V. Stambolija, T. Murselovic, J. Katancic Holjevac,
S. Uzun, V. Djuzel, S. Seiwerth and P. Sikiric. Med. Fac.,
Univ. of Zagreb and Fac. of Vet. Med., Univ. of Zagreb, Croatia.
B256 1061.4 Soluble epoxide hydrolase inhibitors are first in
class therapeutic candidates for chronic and intractable pain in
man and companion animals B. Inceoglu. Univ. of California,
Davis.
B257 1061.5 The development of bifunctional ligands as
novel therapeutics for chronic pain J. LaVigne, K. Edwards,
E. Bilsky, F. Porreca, S. Ananthan, E. Roberts, V. Hruby
and J.M. Streicher. Univ. of New England, Univ. of Arizona,
Southern Res. Inst. and The Scripps Res. Inst.
B258 1061.6 Subpopulation of highly reactive cysteines
underlie the activation of TRPA1 by electrophiles T. TaylorClark and P. Bahia. Univ. of South Florida.
B259 1061.7 A novel class of allosteric ligands modulating
TRPA1: discovery of a switch in agonist-antagonist function
J.M. Herz, Y. Zhu, Y. Lu, E. Kesicki, W.J. Thomsen and M.
Zhu. Algomedix Inc., Mill Creek, WA and Univ. of Texas Hlth.
Sci. Ctr. at Houston.
B260 1061.8 Dietary supplements influence activity of acidsensing ion channels A. Agharkar and E.B. Gonzales. Univ.
of North Texas Hlth. Sci. Ctr., Cardiovasc. Res. Inst. and Inst.
for Aging and Alzheimer’s Dis. Res., Fort Worth.
B261 1061.9 Polar substitutions in the ion-conducting pore
of GLIC alter gating and alcohol modulation J-A.M. Facey, L.C.
Venner, M.J. Hyde, I. Pouya, E. Lindahl and R.J. Howard.
Skidmore Col. and Royal Inst. of Technol., Stockholm.
1062.PROTEINS AS DRUG TARGETS
Poster
B262 1062.1 Characterization of a repurposed agent as a
potent inhibitor of DGKa S. Boroda, T.E. Harris, B.W. Purow
and D.H. Floyd. Univ. of Virginia.
B263 1062.2 Aquaporin-1 translocation and degradation
mediates the water transportation X. Li, J. Zhang and Y. An.
Peking Univ.
B264 1062.3 Elucidating the role of inhibitory G-protein, Gz,
in β-cell preservation and regeneration A.L. Brill, R.L. Pasker,
M.F. Thompson, M.T. Cadena, H.K. Brar, J.C. Neuman and
M.E. Kimple. Univ. of Wisconsin-Madison.
B265 1062.4 Structure-function analysis of a small-molecule
binding site in Kir1.1 and Kir7.1 S.V. Kharade and J.S. Denton.
Vanderbilt Univ.
B266 1062.5 Modulation of the epithelial barrier by a
fragment of Clostridium perfringens iota-toxin D. Iguchi, T.
Hayaishi, S.M. Krug, A. Watari, M. Fromm, K. Yagi and M.
Kondoh. Grad. Sch. of Pharmaceut. Sci., Osaka Univ. and
Charité, Free Univ. and Humboldt Univ., Berlin.
B267 1062.6 Claudin-1 as a target for modulation of
epidermal barriers M. Nakajima, M. Yamashita, A. Watari,
K. Yagi, M. Fukasawa and M. Kondoh. Grad. Sch. of
Pharmaceut. Sci., Osaka Univ. and Natl. Inst. of Infect. Dis.,
Tokyo.
B268 1062.7 Tumor-targeting and anti-tumor activity of anticlaudin-3/-4 antibody Y. Kimura, X. Li, M. Iida, M. Tada, A.
Ishii, A. Watari, M. Fukasawa, K. Yagi and M. Kondoh. Grad.
Sch. of Pharmaceut. Sci., Osaka Univ. and Natl. Inst. of Infect.
Dis., Tokyo.
B269 1062.8 Development and anti-tumor activities of
claudin-4-specific monoclonal antibodies Y. Kawahigashi, X.
Li, H. Kuniyasu, M. Fukasawa, M. Tada, A. Ishii, A. Watari,
K. Yagi and M. Kondoh. Grad. Sch. of Pharmaceut. Sci.,
Osaka Univ., Nara Med. Univ., Natl. Inst. of Infect. Dis., Tokyo
and Natl. Inst. of Hlth. Sci., Tokyo.
B270 1062.9 In vivo inhibition of hepatitis C virus infection
by anti-Claudin-1 monoclonal antibodies M. Iida, S. Nagase,
M. Yamashita, Y. Shirasago, M. Fukasawa, M. Tada, A. Ishii,
A. Watari, K. Yagi and M. Kondoh. Osaka Univ. Grad Sch.
of Pharmaceut. Sci., Natl. Inst. of Infect. Dis., Tokyo, Tokyo
Univ. of Sci. Grad. Sch. of Biol. Sci. and Natl. Inst. of Hlth. Sci.,
Tokyo.
B271 1062.10 Regulated ubiquitination and SUMOylation of
pregnane X receptor M. Sun and J.L. Staudinger. Univ. of
Kansas.
B272 1062.11 Sumo-modification of pxr alters protein cofactor
interactions S. Woody and J.L. Staudinger. Univ. of Kansas.
1063.RENAL PHARMACOLOGY/TOXICOLOGY
Poster
B273 1063.1 Role
of
renal
biotransformation
in
3,4,5-trichloroaniline nephrotoxicity in vitro G. Rankin, D.
Anestis and C. Racine. Marshall Univ.
352
TUESDAYPHARMACOLOGY
B274 1063.2 4-Phenylbutyrate protects renal proximal
tubular cells from palmitic acid-induced endoplasmic reticulum
stress and cell death S. Munusamy, D. Alkhiyami, S. Berzou,
A. Moeinzadeh and H. Mohamed. Qatar Univ.
B275 1063.3 The effect of glutamine, glutathione and
glutamine plus glutathione as substrates for the preservation
of the isolated perfused rabbit kidney M.C. Fonteles, J.E.
Sousa-Filho, N.R.F. Nascimento and R.M. Araújo-Filho.
Ceará State Univ. and Fed. Univ. of Ceará, Brazil.
B276 1063.4 Anemia in adenine-induced chronic renal
failure and the influence of treatment with gum acacia thereon
B.H. Ali, M. Al Z’aabi, A. Ramkumar and A. Nemmar. Sultan
Qaboos Univ., Oman and United Arab Emirates Univ.
B277 1063.5 Pinitol
ameliorates
impaired
pressurenatriuresis in experimental diabetes N.R. Nascimento,
L.U.A.D.S. Cortez, L.G.F. Sousa, M.C. Fonteles and C.F.
Santos. Ceara State Univ., Brazil.
B278 1063.6 Contribution of guanine nucleotide exchange
factor Vav2 to homocysteine-induced NLRP3 inflammasome
activation in mouse podocytes J.M. Abais, M. Xia, K.M. Boini
and P-L. Li. Virginia Commonwealth Univ.
B279 1063.7 Mitochondrial superoxide generation in the
rat pup kidney during sepsis C.R. Sims, N.K. Patil, L.A.
MacMillian-Crow and P.R. Mayeux. Univ. of Arkansas for
Med. Sci.
1064.PHARMACOKINETICS, TRANSPORTERS AND
DRUG METABOLISM
Poster
B280 1064.1 Pharmacokinetic
and
pharmacodynamic
properties of β-hydroxyphospho-carnitine B. Mendoza-Rivera,
J. Reyes-Esparza, R. De La Cruz Cordero and L. RodriguezFragoso. Fac. of Pharm., UAEM, Cuernavaca and Nucitec SA
de CV, Querétaro, Mexico.
B281 1064.2 Piperine and ketoconazole increase plasma
domperidone concentrations in the rat M.S. Alhumayyd, I.A.
Bukhari and A.A. Almotrefi. Col. of Med., Riyadh.
B282 1064.3 Gender comparison of recovery from
intravenous and inhalational anaesthetics among adult patients
in South-West Nigeria Y.O. Okunoren-Oyekenu, A.A. Sanusi
and G.O. Gbotosho. Univ. of Ibadan, Nigeria and Univ. of
Leicester.
B283 1064.4 Pharmacokinetics
and
metabolism
of
clausenamide enantiomers C-j. Zhu and J-t. Zhang. Inst. of
Materia Medica, Chinese Acad. of Med. Sci. & Peking Union
Med. Col.
B284 1064.5 Pharmacokinetic study of two docetaxel
preparations in Beagle dogs by a LC-MS/MS method X.
Huang, G. Liu, Z. Jiang and L. Zhang. China Pharmaceut.
Univ.
B285 1064.6 Sequential hydrolysis of dabigatran etexilate
to its active metabolite by human carboxylesterase 1 and 2
Z. Hu, R.B. Parker, V.L. Herring and S.C. Laizure. Univ. of
Tennessee Hlth. Sci. Ctr.
B286 1064.7 Pharmacokinetics and tissue distribution study
of clevidipine and its metabolite in dogs and rats W. Li. Tongji
Med. Col., Huazhong Univ., China.
B287 1064.8 Organization of cytochrome P450 system
components in the endoplasmic reticulum J.W. Park, J.R.
Reed, G.F. Cawley, M.K. Eyer and W.L. Backes. LSU Hlth.
Sci. Ctr.-New Orleans.
B288 1064.9 Application
of
physiologically-based
pharmacokinetic modeling in hepatic impairment populations
J.E. Sager, M. Hsu, N. Isoherranen, L.C. Wienkers, J.L.
Wahlstrom and R.S. Foti. Univ. of Washington Sch. of Pharm.
and Amgen Inc.
B289 1064.10 The human testis as a model of retinoic acid
formation S. Arnold, T. Kent, S. Schlatt, B.P. Prasad, M.
Haenisch, C. Muller, C. Hogarth, M. Griswold, J. Paik, T.
Walsh, J. Amory and N. Isoherranen. Univ. of Washington,
Washington State Univ. and Univ. of Münster.
B290 1064.11 Human bronchiolar epithelial cells functionally
express P-glycoprotein and multidrug resistance-related
protein-1 V.E. Muchitsch, J.C. Gausterer, J.J. Salomon and
C. Ehrhardt. Sch. of Pharm. and Pharmaceut. Sci., Trinity Col.
Dublin.
B291 1064.12 Lanthanide resonance energy transferbased distance measurements in the mammalian glutamate
transporter excitatory amino acid transporter 3 K. Saha, S.K.
Venkatesan, A. Sohail, T. Stockner, W. Sandtner, G.F. Ecker
and H. Sitte. Med. Univ. Vienna and Univ. of Vienna.
B292 1064.13 Selective interactions of HIV protease inhibitors
with human plasma membrane monoamine transporter and
organic cation transporters H. Duan, Y. Pan, P. Swaan, J.
Unadkat and J. Wang. Univ. of Washington and Univ. of
Maryland Baltimore.
B293 1064.14 Role of the blood-brain barrier in limiting CNS
uptake of pyrethroid insecticides: findings with hCMEC cells as
a proxy J.V. Bruckner. Univ. of Georgia.
B294 1064.15 Investigation into the predominate mechanism
of OAT1 inhibition R.M. Pelis, L. Ingraham and M. Li.
Dalhousie Univ., Canada.
B295 1064.16 A renal-like organic anion transport system in
the ciliary body epithelium of the eye J. Lee and R.M. Pelis.
Dalhousie Univ., Canada.
B296 1064.17 Organic anion transporting polypeptide 1B3
can form homodimers Y. Zhang and B. Hagenbuch. Univ. of
Kansas Med. Ctr.
B297 1064.18 The orally active male contraceptive agent
H2-gamendazole interacts with organic anion transporting
polypeptides expressed in human hepatocytes J. Shoop, L.
Holets, S.R. Jakkaraj, G. Georg, C. Flynn, M. Baltezor, J.S.
Tash and B. Hagenbuch. Univ. of Kansas Med. Ctr., Univ. of
Minnesota, Minneapolis and Univ. of Kansas.
B298 1064.19 Transient knockdown of SULT4A1 induces
upregulation of phototransduction proteins F. Crittenden, C.
Ethen, Z. Wu, D. Chen, T. Kraft, J. Parant and C.N. Falany.
Univ. of Alabama at Birmingham and R&D Systs., Minneapolis.
1065.VASCULAR SMOOTH MUSCLE
PHARMACOLOGY
Poster
B299 1065.1 Exploring the role of the unique N-termini of
PDE4D variants in regulating mural cell morphology, migration
and cAMP signaling S.I. Freitag, T. Truong, P. Brzezinska,
M.B. Umaña, S.N. Rampersad, A.R. Wudwud, F. Hubert and
D.H. Maurice. Queen’s Univ., Canada.
353
T
U
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PHARMACOLOGYTUESDAY
B300 1065.2 J20619 inhibits PDGF-BB-stimulated vascular
smooth muscle cell proliferation and migration L-h. Fang, J.
Guo, L. Li, Y-j. Wu, Y. Yan, X-n. Xu, S-b. Wang, T-y. Yuan and
G-h. Du. Inst. of Materia Medica, Chinese Acad. of Med. Sci. &
Peking Union Med. Col.
B301 1065.3 Target of selective cyclic nucleotide
phosphodiesterases differentially regulates arterial myocyte
migration P. Brzezinska, F. Hubert, S.N. Rampersad, A.R.
Wudwud, S.I. Freitag, M.B. Umana and D.H. Maurice.
Queen’s Univ., Canada.
B302 1065.4 Alpha1-adrenergic receptor subtype specific
activation of ERK in human primary smooth muscle cells
K.M. Brown, T.D. Aungst, C. Castro, A. Bommareddy, A.L.
VanWert and D.F. McCune. Wilkes Univ.
B303 1065.5 A novel anti-inflammatory signaling role for the
deubiquitinase USP20 in vivo P-Y. Jean-Charles, L. Zhang,
S-o. Han, R.P. Kommaddi, J-H. Wu, N.J. Freedman and S.K.
Shenoy. Duke Univ. Med. Ctr.
B304 1065.6 Regulation
of
phenotype-associated
phosphodiesterase expression in human vascular smooth
muscle cells by co-culture with endothelial cells: role of shear
stress F. Hubert, P. Brzezinska, S.N. Rampersad and D.H.
Maurice. Queen’s Univ., Canada.
B305 1065.7 5-Hydroxytryptamine mediated vasocontraction
and Ca2+/Calmodulin and Src-kinase dependent Epidermal
Growth Factor Receptor Transactivation in Rat aorta S. Guner,
I. Ozakca, H.B. Kandilci, T. Zoto-Mustafayeva, B. DumanDalkilic and H. Gurdal. Ufuk University, School of Medicine,
Ankara University, School of Pharmacy and Ankara University,
School of Medicine.
B306 1065.8 Angiotensin II-induced arterial fibrosis and
stiffness is prevented in arginase 1-deficient mice A. Bhatta,
Z. Xu, R. Caldwell and R.W. Caldwell. Georgia Regents Univ.
B307 1065.9 Suramin sensitive P2 receptor is involved in α1adrenergic receptor mediated mesenteric arterial constriction
in normotensive and DOCA-salt hypertensive rats M.H. Lian,
H. Xu and J.J. Galligan. Michigan State Univ.
B308 1065.10 NADPH oxidase mediates altered vascular
responses in allergic mice D.S. Ponnoth and S.J. Mustafa.
West Virginia Univ.
B310 1065.12 Activation of vascular Toll-like receptor 3
induces phosphorylation of caldesmon via ERK1/2 pathway
M.A. Carrillo-Sepulveda, T. Hardigan and R.C. Webb.
B311 1065.13 Stromal interaction molecule 1 deletion in
smooth muscle cells protects hypertension-induced vascular
dysfunction by endoplasmic reticulum stress-dependent
mechanism M. Kassan, S. Belmadani, M. Trebak and K.
Matrougui. Eastern Virginia Med. Sch. and Univ. at Albany.
B312 1065.14 G protein-coupled estrogen receptor mediates
relaxation of coronary arteries via cAMP/PKA-dependent
activation of MLCP X. Yu, J.N. Stallone and G. Han. Texas
A&M Univ.
B313 1065.15 Nitric oxide attenuates the enhanced
expression of Giα proteins in vascular smooth muscle cells
from spontaneously hypertensive rats: molecular mechanisms
O. Sarkar, R. Paul and M.B. Anand-Srivastava. Univ. of
Montreal.
B314 1065.16 Contribution of nuclear factor E2-related factor
2 to the atherogenic phenotype transition in coronary arterial
smooth muscle cells lacking CD38 gene M. Xu, X. Li, M.
Wang, Y. Zhang and P-l. Li. Virginia Commonwealth Univ.
354
B315 1065.17 Early life stress induces bladder dysmotility
in adult rats D. Kennedy, E. Mohammadi, R. Hurst and B.
Greenwood-Van Meerveld. Univ. of Oklahoma Hlth. Sci. Ctr.
1066.GPCR’S II
Poster
B316 1066.1 Identification of novel signaling regulators of
the mu opioid receptor K.A. Edwards, J. LaVigne, E. MosesFynn, N. Mullen and J.M. Streicher. Univ. of New England.
B317 1066.2 Analysis of functional selectivity at the
nociceptin opioid receptor S.D. Chang, S. Spangler, N. Zhang,
W. Planer, F.I. Carroll and M.R. Bruchas. Washington Univ. in
St. Louis and RTI Intl., Research Triangle Park.
B318 1066.3 Chronic baclofen treatment influences GABAB
activation of G-proteins and phosphorylation of FAK, GSK3β,
and DARPP32 in mesocorticolimbic rat brain regions B.M.
Keegan, T.J. Beveridge, J.J. Pezor, R. Xiao, T. Sexton, S.R.
Childers and A.C. Howlett. Wake Forest Univ.
B319 1066.4 GPCRs are regulators of MRTF-A and YAP
mediated CCN1 expression O.M. Yu, S. Miyamoto and J.M.
Heller Brown. UCSD.
B320 1066.5 Phospholipase C-epsilon links G-protein
coupled receptor activation to inflammatory responses in
astrocytes S. Dusaban, N.H. Purcell, M.T. Kunkel, A. Smrcka
and J. Heller Brown. UCSD and Univ. of Rochester.
B321 1066.6 GPCRs and heterotrimeric G proteins directly
regulate membrane type-1 matrix metalloprotease A.C.
Overland and P. Insel. UCSD.
B322 1066.7 Structural requirements for FPR2/ALX
interaction with formyl peptides R.D. Ye, H-Q. He, E.L. Troksa,
G. Caltabiano and L. Pardo. Shanghai Jiao Tong Univ., Univ.
of Illinois at Chicago and Autonomous Univ. of Barcelona,
Bellaterra.
B323 1066.8 Pre-exposure of the urotensin II receptor to
urotensin II or urotensin II-related peptide differentially reduces
the response to subsequent additions T.K. Warren and S.D.
Clark. Univ. at Buffalo, Amherst and Univ. at Buffalo.
B324 1066.9 Angiotensin-II mediates ACE2 internalization
and degradation through an angiotensin-II type I receptordependent mechanism C. Filipeanu, M.R. Deshotels, H. Xia
and E. Lazartigues. Col. of Med., Howard Univ. and LSU Hlth.
Sci. Ctr. , New Orleans.
B325 1066.10 Effects of eicosapentaenoic acid and the
GPR120 agonist TUG-891 on lysophosphatidic acid signaling
in human prostate cancer cells M.M. Hopkins, Z. Liu and K.E.
Meier. Washington State Univ.
B326 1066.11 GPCRs as potential therapeutic targets in
pancreatic cancer-associated fibroblasts S. Zhou and T.
McCann. UCSD.
B327 1066.12 Fingerprinting of GPCR activity across multiple
G protein substrates unveils complex profiles of functional
selectivity I. Masuho, C.D. Jones and K.A. Martemyanov.
Scripps Florida, Jupiter.
B328 1066.13 Glycosylation of protease-activated receptor-1
regulates G12/13 versus Gq signal pathway bias T.H. Smith,
A.G. Soto, B. Chen and J. Trejo. UCSD.
B329 1066.14 Thrombin-bound
dabigatran
modulates
protease-activated receptor-1 expression B. Chen, A. Soto,
A. Goss, J. VanRyn and J. Trejo. UCSD and Boehringer
Ingelheim Pharmaceuts. Inc., CT.
TUESDAYPHARMACOLOGY/PHYSIOLOGY
B330 1066.15 Ubiquitination of PAR1 nucleates a noncanonical p38 signaling pathway to regulate thrombin-induced
vascular leakage N.J. Grimsey, T.H. Smith, P. Le and J. Trejo.
UCSD.
B331 1066.16 Palmitoylation is required for activated PAR1
ubiquitination and p38 MAPK signaling I. Canto, N. Grimsey
and J. Trejo. UCSD.
B332 1066.17 Understanding the mechanism of biased
agonism at chemokine receptors S. Rajagopal, D.L. Bassoni,
J.J. Campbell, N.P. Gerard, C. Gerard and T.S. Wehrman.
Duke Univ. Med. Ctr., DiscoveRx Corp., Fremont, CA, Brigham
and Women’s Hosp. and Children’s Hosp., Boston.
B333 1066.18 The ubiquitin ligase Deltex-3L regulates
endosomal sorting of the G protein-coupled receptor CXCR4 J.
Holleman and A. Marchese. Loyola Univ. Chicago, Maywood.
Physiology
1067.BLOOD PRESSURE REGULATION III
Poster
A1
1067.1 Inhibition of microRNA-429 in the renal medulla
increased salt sensitivity of arterial blood pressure in Sprague
Dawley rats Q. Zhu, J. Hu, Z. Wang, P-L. Li, W. Han and N.
Li. Virginia Commonwealth Univ.
A2
1067.2 Essential role of mTORC1 in the hypertension
induced by overactivation of the brain renin-angiotensin system
K. Muta, J.L. Grobe, C.D. Sigmund and K. Rahmouni. Univ.
of Iowa.
A3
1067.3 Hypoxic incubation alters cardiovascular
response to Ang II in embryonic chickens (Gallus gallus) K.
Tate and D. Crossley. Univ. of North Texas.
A4
1067.4 Concentration-dependent effects of zinc on
angiotensin-converting enzyme-2 activity R.C. Speth, E.J.
Carrera, M. Jean-Baptiste, A. Joachim and A. Linares.
Nova Southeastern Univ.
A5
1067.5 Inhibition of angiotensin-converting enzyme-2
(ACE-2) activity and radioligand binding of a putative ACE-2
inhibitor A. Linares, E.J. Carrera and R.C. Speth. Farquhar
Col. of Arts and Sci., FL and Nova Southeastern Univ.
A6
1067.6 MCA-APK(Dnp) is not a selective substrate of
angiotensin-converting enzyme-2 E.J. Carrera, A. Linares,
A. Joachim, M.J. Jean-Baptiste and R.C. Speth. Nova
Southeastern Univ.
A7
1067.7 Major role of ryanodine type 2 receptors in
global and local intracellular calcium release in arterial smooth
muscle M. Kassmann, J. Schleifenbaum, I.A. Szijártó, Y-M.
Anistan and M. Gollasch. Charité Campus Buch and Charité
Campus Virchow Clin., Berlin.
A8
1067.8 Stretch-activation of angiotensin II type
1a receptors contributes to the myogenic response of
mouse mesenteric and renal arteries J. Schleifenbaum,
M. Kassmann, I.A. Szijártó, H.C. Hercule, S. Weinert, M.
Heidenreich, A.R. Pathan, Y-M. Anistan, N. Alenina, N.J.
Rusch, M. Bader, T.J. Jentsch and M. Gollasch. Charité
Campus Buch, Leibniz Inst. for Molec. Pharmacol., Max
Delbrück Ctr. for Molec. Med., Berlin, Univ. of Arkansas for
Med. Sci. and Charité Campus Virchow Clin., Berlin.
A9
1067.9 The effect of peroxisome proliferator activated
receptor -α activation and apocynin on superoxide dismutase
and NADPH oxidase expression in the brains of mice during
angiotensin II-induced hypertension M. Bouchelion, A.
Mervin, D.L. Lee and J.S. Allard. Howard Univ.
A10
1067.10 Transient receptor potential vanilloid type 4
channel as a putative target molecule for anti-hypertensive
therapy D. Walas and J.F.R. Paton. Univ. of Bristol.
A11
1067.11 NHERF-1 expression in aging kidney tubular
apical and basolateral membranes S.J. Khundmiri, R.
Murray, A.J. LeBlanc, U. Sen, E.D. Lederer, P.A. Jose and
E.J. Weiman. Univ. of Louisville,Robley Rex Veterans Med.
Ctr. and Univ. of Maryland Sch. of Med.
1068.CEREBRAL AUTOREGULATION IN
PATHOLOGICAL CONDITIONS
Poster
A12
1068.1 Contribution of voltage-gated potassium
channels in cerebrovascular dysfunction associated with a
genetic model of ischemic small vessel disease F. Dabertrand,
C. Krøigaard, A.D. Bonev, J.E. Brayden, A. Joutel and M.T.
Nelson. Univ. of Vermont Col. of Med. and INSERM U740,
Facc. of Med. Paris 7.
A13
1068.2 The cytokines TNF, MCP-1 and CINC-1
mediate diminished dilation of middle cerebral artery after
ischemic stroke in rats Z. Broskova, D.C. Anthony and Z.
Bagi. Univ. of Oxford and Georgia Regents Univ.
A14
1068.3 Sudden onset of hearing loss after cerebral
ischemia P.K. Kamat, A. Kalani, S.C. Tyagi and N. Tyagi.
Univ. of Louisville.
A15
1068.4 Improving the sensitivity of neurovascular
coupling assessment using motor-cognitive paradigms poststroke A.M. Salinet, T.G. Robinson and R.B. Panerai. Univ.
of Leicester.
A16
1068.5 Dynamic
cerebral
autoregulation
is
heterogeneous in different subtypes of acute ischemic stroke
Z-N. Guo, J. Liu, Y. Xing and Y. Yang. First Norman Bethune
Hosp. of Jilin Univ. and Shenzhen Insts. of Adv. Technol.,
Chinese Acad. of Sci.
A17
1068.6 Brain tissue oxygenation in response to
changes in arterial pressure in patients with mild cognitive
impairment J. Liu, T. Tarumi, B.Y. Tseng, C. Hill, K.
Armstrong, L.S. Hynan, T. Hodics and R. Zhang. Texas Hlth.
Presbyterian Hosp. Dallas and Univ. of Texas Southwestern
Med. Ctr.
355
T
U
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PHYSIOLOGYTUESDAY
A18
1068.7 Dynamic cerebral autoregulation and tissue
oxygenation in amnestic mild cognitive impairment T. Tarumi,
D.I. Dunsky, M. Ayaz, J. Liu, C. Hill, K. Armstrong, K.
Martin-Cook, M. Cullum and R. Zhang. Inst. for Exercise
and Envrn. Med., Dallas, Univ. of Texas Southwestern Med.
Ctr. and University of Texas Southwestern Medical Center at
Dallas.
A19
1068.8 Regional cerebral blood flow responses to rapid
reductions in blood pressure after high level spinal cord injury:
the effect of alpha1-agonist A.A. Phillips, A.V. Krassioukov,
P.N. Ainslie and D. Warburton. Univ. of British Columbia and
Univ. of British Columbia Sch. of Exercise and Hlth. Sci.
A20
1068.9 Cerebral blood flow regulation during blood
loss compared to lower body negative pressure in humans J.N.
Barnes, B.D. Johnson, V.A. Convertino, M.J. Joyner and
C.A. Rickards. Mayo Clin., U.S. Army Inst. of Surg. Res., Fort
Sam Houston and Univ. of North Texas Hlth. Sci. Ctr.
A21
1068.10 Cerebral autoregulation in fulminant hepatic
failure R.C. Nogueira, F.P. Mendes, M.L. Pacheco, K. Lins,
M.J. Teixeira and E. Bor-Seng-Shu. Univ. of São Paulo Sch.
of Med.
A22
1068.11 Dynamic cerebral pressure-flow relationships
in aging and long-term heart transplant recipients J. Smirl,
M. Haykowsky, K. Marsden, H. Jones, M. Nelson and P.N.
Ainslie. Univ. of British Columbia Okanagan, Univ. of Alberta,
Liverpool John Moores and Cedars-Sinai Med. Ctr.
A23
1068.12 Blunted
cerebrovascular
response
to
exogenous nitric oxide in POTS A. Del Pozzi, M.S. Medow
and J.M. Stewart. New York Med. Col.
A24
1068.13 tPA-S481A
prevents
impairment
of
cerebrovascular autoregulation by endogenous tPA after
traumatic brain injury by upregulating p38 MAPK and inhibiting
ET-1 W.M. Armstead, L-E. Bohman, J. Riley, S. Yarovoi,
A.A-R. Higazi and D.B. Cines. Univ. of Pennsylvania.
A25
1068.14 Uncoupling of flow-pressure relationships
following sport concussion in elite athletes S.A. Bishop,
T. Burnett, J. Smirl, P. Ainslie, P. van Donkelaar and P.
Neary. Univ. of Regina, Canada and Univ. of British Columbia
Okanagan.
A26
1068.15 Reduced vestibular function in veterans is
associated with worse cerebral autoregulation J.M. Serrador,
A.M. Acosta, B.M. Ghobreal and M. Blatt. Rutgers Biomed.
and Hlth. Sci. and VA New Jersey Hlth. Care Syst., East
Orange.
A27
1068.16 Cerebral blood flow regulation is affected
immediately following a concussion J.M. Tosto, M.J. Falvo,
L.A. Reyes, M. Blatt, B. Ghobreal and J.M. Serrador. VA
New Jersey Hlth. Care Syst. East Orange and Rutgers Biomed.
Hlth. Sci., Newark.
A28
1068.17 Two approaches to the pressure-volume
relationship after traumatic brain injury using respiratory stimuli
C. Haubrich. Aachen Univ., Germany.
A29
1068.18 Post-traumatic stress disorder does not affect
cerebrovascular reactivity J. Stojanovic-Radic, L. Reyes, B.
Ghobreal, M. Blatt, A. Acosta, H. Chandler and J. Serrador.
VA New Jersey Hlth. Care Syst. and Rutgers Univ., Newark.
A30
1068.19 Autonomic dysfunction in veterans with Gulf
War illness L.A. Reyes, M.J. Falvo, M. Blatt, B. Ghobreal,
A. Acosta and J.M. Serrador. VA New Jersy Hlth. Care Syst.,
East Orange and Rutgers Biomed. and Hlth. Sci., Newark.
356
1069.CEREBRAL BLOOD FLOW REGULATION IN
AGING
Poster
A31
1069.1 Cerebral autoregulation, individual variability,
and white matter hyperintensity J. Liu, B.Y. Tseng, M.A. Khan,
T. Tarumi, C. Hill, K. Armstrong, N. Mirshams, T. Hodics
and R. Zhang. Texas Hlth. Presbyterian Hosp. Dallas and
Univ. of Texas Southwestern Med. Ctr.
A32
1069.2 Cerebral hemodynamics in normal aging:
associations with central hemodynamics and cerebral small
vessel disease T. Tarumi, M. Ayaz, J. Liu, B.M. Tseng, R.
Parker, R. Jonathan, C. Tinajero, W. Zaidi and R. Zhang.
Inst. for Exercise and Envrn. Med., Dallas and Univ. of Texas
Southwestern Med. Ctr.
A33
1069.3 Reduced cerebral autoregulation as the
genesis of symptoms in orthostatic intolerance in elderly M.
Sanders, A. Meel - van den Abeelen, C. Slump, J. Lagro
and J. Claassen. Radboud Univ. Med. Ctr. and Univ. Twente,
Netherlands.
A34
1069.4 Age-related differences in carotid and cerebral
blood flow regulation S.M. Kruse, S.M. Ranadive, J.L. Taylor,
M.J. Joyner and J.N. Barnes. Mayo Clin.
A35
1069.5 The impact of aging on cerebral vasomotor
reactivity to carbon dioxide J. Riley, T. Tarumi, R. Parker,
K. Armstrong, C. Tinajero and R. Zhang. Texas Hlth.
Presbyterian Hosp. Dallas and Univ. of Texas Southwestern
Med. Ctr.
A36
1069.6 Age- and estrogen-dependent effects on
cerebrovascular reactivity: shifting from beneficial to detrimental
R. Deer, L. Perkins and J.N. Stallone. Texas A&M Univ.
1070.CEREBRAL CIRCULATION II
Poster
A37
1070.1 Enhanced endothelial nitric oxide production
impairs cerebrovascular tone after brain trauma N. Villalba,
T.A. Longden, M.T. Nelson, G.C. Wellman and K. Freeman.
Univ. of Vermont.
A38
1070.2 Vigorous treadmill exercise improves reactivity
of cerebral arterioles and reduces brain injury following
transient focal ischemia D.M. Arrick, S. Yang, C. Li, H. Sun
and W.G. Mayhan. LSU Hlth. Sci. Ctr., Shreveport.
A39
1070.3 Antihypertensive therapy reduces myogenic
tone and increases the resting diameter of cerebral penetrating
arterioles in hypertensive rats P.W. Pires, W.F. Jackson and
A.M. Dorrance. Michigan State Univ.
A40
1070.4 Mild deoxycorticosterone (DOCA)/salt-induced
hypertension causes cerebral microvascular dysfunction via a
rho kinase dependent mechanism T.M. De Silva, C.M. Lynch,
J.L. Grobe and F.M. Faraci. VA Healthcare Syst. and Univ. of
Iowa.
A41
1070.5 Pulse
pressure
oscillations
regulate
cerebrovascular reactivity to flow A. Raignault, V. Bolduc,
F. Lesage and É. Thorin. Montreal Heart Inst. and Servier,
Suresnes.
TUESDAYPHYSIOLOGY
A42
1070.6 Modulation of pressure-dependent cerebral
arterial myogenic tone by a redox-sensitive signaling event
D. Gebremedhin, K. Rarick and D.R. Harder. Med. Col. of
Wisconsin.
A43
1070.7 Nebivolol reduces intracellular Ca2+ and elicits
dilations in isolated rat basilar arteries P. Cseplo, Z. Vamos,
I.Z. Batai, O. Torok, Z. Springo, A. Toth and A. Koller. Petz
Aladar County Trng. Hosp., Gyor, Univ. of Pecs Med. Sch. and
Szentagothai Res. Ctr., Natl. Ambulance Svc., Budapest, Univ.
of Debrecen, Hungary and New York Med. Col.
A44
1070.8 Dynamic and static factors predicting
vasomotor reactivity in forced hypocapnia M. Müller and M.
Österreich. Hosp. Cantonal Lucerne.
A45
1070.9 Caffeine protects cerebral artery function in the
reduced uterine perfusion pressure model of preeclampsia S.
Dennis, B. Balser, R. Powers, J. Novak and R.J. Ramirez.
Walsh Univ., Univ. of Akron and Univ. of Pittsburgh & Magee
Womens Res. Inst.
A46
1070.10 SIRT1 overexpression protects against high
fat diet-induced cerebral artery endothelial dysfunction A.E.
Walker, G.D. Henson, K.D. Reihl, L.A. Lesniewski and A.J.
Donato. Univ. of Utah.
A47
1070.11 Effects of aging and high fat diet on endothelial
function in middle cerebral arteries is not additive K. Reihl, A.
Walker, G. Henson, A. Donato and L. Lesniewski. Univ. of
Utah.
1071.CORONARY CIRCULATION
Poster
A48
1071.1 A2A adenosine receptor-mediated increase
in coronary flow is dependent on NADPH oxidase-derived
reactive oxygen species H. Labazi, U. Rajamani, S.L. Tilley,
C. Ledent and S.J. Mustafa. West Virginia Univ., Univ. of
North Carolina at Chapel Hill and Univ. Libre de Bruxelles.
A49
1071.2 Time course of coronary vasodilator response
to intravenous adenosine in humans Z. Gao, K.D. Monahan,
K. Brandt, C. Blaha, M. Herr and L.I. Sinoway. Penn State
Hershey Heart and Vasc. Inst.
A50
1071.3 Inhibition of soluble epoxide hydrolase by
t-AUCB modulates coronary reactive hyperemia in isolated
mouse hearts A. Hanif, C. Morisseau and M.A. Nayeem.
West Virginia Univ. and Univ. of California, Davis.
A51
1071.4 Coronary perivascular adipose tissue and K+
channel-mediated vasodilation in lean and obese hearts J.N.
Noblet, M.K. Owen, A.G. Goodwill, G.M. Dick and J.D. Tune.
Indiana Univ. Sch. of Med., Univ. of North Carolina at Chapel
Hill and West Virginia Univ. Sch. of Med.
A52
1071.5 ADAM17 mediates TNF release from
pericardial adipose tissue arteries to remotely impair coronary
dilation in patients with type 2 diabetes H. Dou, A. Feher, M.
Romero and Z. Bagi. Georgia Regents Univ.
A53
1071.6 Attenuated insulin induced dilation in coronary
arteries from obesity resistant and obesity prone high fat fed
rats C.L. Oltman and B.L. Dake. Univ. of Iowa and VA Hlth.
Care Syst.
A54
1071.7 Temporal response of monocytes during
progressive coronary artery occlusion N. Hakimzadeh, P. van
Horssen, M. van Lier, J. van den Wijngaard, C. Belterman,
R. Coronel, J. Piek, J. Spaan, H. Verberne and M. Siebes.
Acad. Med. Ctr., Univ. of Amsterdam.
A55
1071.8 Coronary vascular function is improved in
ischemic patients after continuous-flow left ventricular assist
device implantation L. Deeter, N. Diakos, J. Stehlik, C.
Selzman, A. Kfoury, B. Reid, A. Saidi, O. Wever-Pinzon,
D.R. Verma, C-G. Yen, E. Uzoigwe, S. Guo, D. Li, S. Drakos
and J.D. Symons. Univ. of Utah.
A56
1071.9 Role for DNA repair signaling in coronary
artery stenosis J. Meloche, A. Pflieger, S. Provencher and S.
Bonnet. Laval Univ.
1072.DIABETES AND INSULIN RESISTANCE III
Poster
A57
1072.1 Sodium butyrate remodels whole genome
nucleosome maps and attenuates high fat diet-induced
mitochondrial dysfunction in skeletal muscle from C57BL6/J
mice T.M. Henagan, A.M. Navard and J. Ye. Purdue Univ. and
Pennington Biomed. Res. Ctr., Baton Rouge.
A58
1072.2 Reversion from a high-fat diet to a prenatal
normal diet could delay the incidence of insulin resistance
induced by postnatal high fat diet in female offspring B. Keith,
L. Zhou and L. Xie. Univ. of North Dakota Sch. of Med. Sci.
A59
1072.3 Gestational chronic intermittent hypoxia alters
glucose homeostasis in rat male offspring W. Iqbal, D.B. Hardy
and J. Ciriello. Univ. of Western Ontario.
A60
1072.4 Impaired fasting blood glucose and circulating
endothelial progenitor cell function T.D. Bammert, C.A.
Beckstrom, K.J. Diehl, P.J. Kavlich, J.J. Greiner, B.L.
Stauffer and C.A. DeSouza. Univ. of Colorado Boulder.
A61
1072.5 Endothelial peNOS signaling and ET-1 mRNA
expression during acute hyperinsulinemia in type 2 diabetes
L.J. Boyle, J. Padilla, D.P. Credeur, P.J. Fadel and J.P.
Thyfault. Univ. of Missouri-Columbia.
A62
1072.6 Diabetes complications in congenic leptin
receptor deficient BBDR.cg-lepr.cp rats L.M. Berglund,
L. Åkesson, E. Garcia Vaz, A.V. Zetterqvist, O. Kotova,
A-M. Dutius Andersson, M. Johansson, N. Wierup, A-C.
Jönsson-Rylander, Å. Lernmark and M.F. Gomez. Lund
Univ. and Astra Zeneca R&D, Sweden.
A63
1072.7 Impaired
autonomic
regulation
in
hyperglycemia and cardiovascular dynamics during autologous
blood donation M. Kamakura, E. Kanno, M. Takahashi and
R. Maruyama. Tohoku Univ. Grad. Sch. of Med. and Miyagi
Univ. Sch. of Nursing, Japan.
A64
1072.8 Astrocyte and microglial activation by insulin/
saline treatment of diabetic ketoacidosis W. Lo, M.E. O’Donnell
and N.S. Glaser. Univ. of California, Davis.
A65
1072.9 Glucose stimulated adipose tissue blood flow
is reduced after high fat feeding despite diminished resistance
artery vasoconstrictor reactivity G.D. Henson, K.D. Reihl, A.J.
Donato, B.J. Behnke and L.A. Lesniewski. Univ. of Utah, VA
Med. Ctr., Salt Lake City and Univ. of Florida.
A66
1072.10 Effect of cold pressor stress on glycemic
response of healthy college aged subjects T.C. Curtis, S.P.
Krause, K.K. Schmit, F. Ragsdale and T. Wilson. Winona
State Univ.
A67
1072.11 Dysregulation of intracellular Ca2+ in
lymphocytes and neutrophils in type 2 diabetic patients
J. Singh, S.S. Kappala, J. Espino, J.A. Pariente, A.B.
Rodriguez and K.R. Bidasee. Univ. of Central Lancashire,
Univ. of Extremadura, Spain and Univ. of Nebraska Med. Ctr.
357
T
U
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PHYSIOLOGYTUESDAY
1073.CARDIAC FUNCTION AND DYNAMICS II
Poster
A68
1073.1 Hemodynamic responses to recumbent
positions in healthy adults K. Sasaki, H. Sato, S. Bao, E.
Kanno and R. Maruyama. Tohoku Univ. Grad. Sch. of Med.
A69
1073.2 Cardiac volume regulation: transition among
two phenotypes in heart failure P.L. Kerkhof, J.K-J. Li,
J.Y. Kresh and G.R. Heyndrickx. VU Univ. Med. Ctr.,
Amsterdam,Rutgers Univ., Piscataway, Drexel Univ. and OLV
Clin., Aalst, Belgium.
A70
1073.3 Sex differences in heart rate variability and
circulation after postural change H. Sato, K. Sasaki, S. Bao,
E. Kanno and R. Maruyama. Tohoku Univ. Grad. Sch. of Med.
A71
1073.4 The contribution of cardiac mechanics to
isolated increases in peripheral blood flow E.J. Stöhr, A. van
Mil, A. Drane and J. Pearson. Cardiff Metropolitan Univ.
A72
1073.5 Respiratory loading causes right-to-left
shunting through the PFO K.L. Moses, M.L. Bates, E.T.
Farrell, L.J. Lamers, F. Baus, D.F. Pegelow and M.W.
Eldridge. Univ. of Wisconsin-Madison.
A73
1073.6 From pre-clinical data to the clinics:
identification of circulating inflammatory mediators as potential
biomarkers for heart failure R. Altara. Maastricht Univ.,
Netherlands.
A74
1073.7 Functional characterization of a newly identified
LMNA mutant in HL-1 cardiomyocytes M. Carmosino, C.
Forleo, F. Pisani, G. Procino, S. Torretta, S. Favale and M.
Svelto. Univ. of Basilicata and Univ. of Bari, Italy.
A75
1073.8 Enzyme-linked immunosorbent assay is a
viable method for determining release kinetics of cardiac
myosin binding protein-C following isoproterenol-induced
cardiac injury A. Jagadeesan, D. Barefield, S. Govindan,
D.W. Kuster and S. Sadayappan. Loyola Univ. Chicago,
Maywood.
1074.HYPERTENSION II
Poster
A76
1074.1 A potential role of memory T cells in
hypertension H.A. Itani, F. Zhang, L. Xiao, W. Chen and D.G.
Harrison. Vanderbilt Univ.
A77
1074.2 Isoketals in monocyte-derived dendritic cells
activate T cells and promote hypertension R. Loperena,
A. Kirabo, L.J. Roberts, S.S. Davies and D.G. Harrison.
Vanderbilt Univ.
A78
1074.3 Interleukin 17A induces renal SGK1 expression
in hypertension A.E. Norlander, M. Saleh, D. Harrison and M.
Madhur. Vanderbilt Univ. Sch. of Med.
A79
1074.4 Effect of low birth weight on inflammation
biomarkers and autonomic function in healthy young adults
S. Bao, K. Sasaki, H. Sato, E. Kanno and R. Maruyama.
Tohoku Univ. Grad. Sch. of Med.
A80
1074.5 Oligoclonal CD8+ cells in the kidney mediate
experimental hypertension D.W. Trott, S.R. Thabet, H.A.
Itani, J. Wu, A.E. Norlander, W. Chen and D.G. Harrison.
Vanderbilt Univ. Med. Ctr.
358
A81
1074.6 Suppressor of cytokine signaling 3 exerts
divergent local vs systemic effects in angiotensin II-induced
endothelial dysfunction Y. Li, D.A. Kinzenbaw, M.L. Modrick
and F.M. Faraci. Univ. of Iowa and VA Healthcare Syst.
A82
1074.7 Inhibition of high salt-induced activation
of NLRP3 inflammasome by mesenchymal stem cell
transplantation in the renal medulla in Dahl S rats X. Li, Q. Zhu,
S. Conley, J. Hu, P-L. Li and N. Li. Virginia Commonwealth
Univ.
A83
1074.8 Comparative assay of oxidative stress
biomarkers on normotensive and hypertensive, premenopausal and postmenopausal women: a pilot study J.I.
Calzada-Frías, G. Lugo-Martínez, C.A. Jiménez-Zamarripa,
M.E. Ocharán-Hernandez, R. Cariño-Cortés and C.C.
Calzada-Mendoza. ENCB, Natl. Polytech Inst., Sch. of Med.,
Natl. Polytech Inst., Psychiat. Hosp. Dr. Samuel Ramírez
Moreno, CICS-Natl. Polytech Inst. and Autonomous Univ. of
Hidalgo State, Mexico City.
A84
1074.9 Increased memory and decreased naïve T
cells in human hypertension P.J. Marvar, T.D. Cruise, E.C.
Hart, A.E. Burchell, L.E. Ratcliffe, A.K. Nightingale and J.F.
Paton. Univ. of Bristol and Bristol Heart Inst.
A85
1074.10 Individual differences in susceptibility to
depression and cardiovascular disease comorbidity in a rat
model of social stress C.M. Lombard, M.N. Melson and S.K.
Wood. Univ. of South Carolina Sch. of Med.
1075.ENDOTHELIAL CELL BIOLOGY III
Poster
A86
1075.1 Calcium/calmodulin-dependent protein kinase
II modulates inositol-3-phosphate receptors in vascular
endothelium from mouse mesenteric arteries F. Toussaint, C.
Charbel, A. Blanchette, P. Comtois and J. Ledoux. Montreal
Heart Inst., Univ. of Montréal and Polytech Montréal.
A87
1075.2 Phospholipase C isoforms expression in
mouse endothelium D. Béziau, F. Toussaint, C. Charbel, N.
Daya, A. Blanchette and J. Ledoux. Montreal Heart Inst. and
Univ. of Montréal.
A88
1075.3 Mitochondrial modulation of calcium pulsars in
native endothelial cells D. Béziau, C. Charbel, F. Toussaint,
A. Blanchette, G. Mayer and J. Ledoux. Univ. of Montreal
and Montreal Heart Inst.
A89
1075.4 CGRP release from perivascular capsaicinsensitive sensory nerves regulates vascular function through
pannexin-1 channel opening P.S. Gaete, M.A. Lillo, I. Poblete
and X.F. Figueroa. Pontifical Catholic Univ. of Chile.
A90
1075.5 The G protein-coupled receptor (GPER/
GPR30) activates endothelial nitric oxide synthase N.C.
Fredette, M.R. Meyer and E.R. Prossnitz. Univ. of New
Mexico and Triemli City Hosp., Zurich.
A91
1075.6 Caffeine
increases
basal
eNOS
phosphorylation and stimulates endothelial cell growth A.M.
Calleo and M.B. Harris. Col. of William & Mary.
A92
1075.7 ACE and iNOS overexpression correlates with
vascular reactivity in young Syrian cardiomyopathic hamsters
N. Cruz, J. Quidgley, L. Dorna, J. Miranda and M.J. Crespo.
Univ. of Puerto Rico-Sch. of Med.
TUESDAYPHYSIOLOGY
A93
1075.8 Effect of aging on eNOS-associated
protein:protein interactions throughout the arterial network M.
Luttrell. Texas A&M Univ.
A94
1075.9 The interplay between eNOS palmitoylation
and phosphorylation: the triacsin C effect N.R. Blakeman and
M.T. Weis. Texas Tech Univ. Hlth. Sci. Ctr., Amarillo.
A95
1075.10 Study on penile corpus cavernosum relaxation
induced by Berberis amurensis Rupr R. Tan, H.Y. Kim, K.W.
Cho, D.G. Kang and H.S. Lee. Wonkwang Univ., South Korea.
1076.VASCULAR PATHOBIOLOGY I
Poster
A96
1076.1 O-GlcNacase
overexpression
restores
coronary endothelial dysfunction in type 1 diabetic mice A. Dai,
R. Donthamsetty, Y. Han, B.T. Scott, H. Wang, W.H. Dillmann
and A. Makino. Univ. of Illinois at Chicago and UCSD.
A97
1076.2 Increased Ca2+-activated Ca2+ influx and
impaired Ca2+ buffering in coronary smooth muscle from
metabolic syndrome Ossabaw swine M.L. McKenney, S.L.
Dineen, J.N. Noblet, J.D. Tune and M. Sturek. Indiana Univ.
Sch. of Med.
A98
1076.3 Changes in vasomotor function following
mitochondria-targeted antioxidant treatment depend on
baseline antioxidant capacity in hypercholesterolemic mice
C.M. Roos, B. Zhang, N.M. Thalji and J.D. Miller. Mayo Clin.
A99
1076.4 Hyal-1 deficiency may protect the endothelium
in a mouse diabetic model S. Dogne, G. Rath, C. Dessy, N.
Caron and B. Flamion. Univ. of Namur, Belgium and Catholic
Univ. of Louvain.
A100 1076.5 Glucose-6-phosphate
dehydrogenase
is
involved in regulation of arterial smooth muscle phenotype in
metabolic syndrome S.R. Joshi, M. Alloosh and S.A. Gupte.
New York Med. Col. and Indiana Univ., Indianapolis.
A101 1076.6 Partial genetic disruption of mTOR complex
1 signaling does not improve vascular endothelial function in
hypercholesterolemic mice A.H. Jbeli, B. Zhang, C.M. Roos,
H. Fujimoto and J.D. Miller. Mayo Clin.
A102 1076.7 Omental fat from obese and obese diabetic
patients dys-regulates vascular function by NF-κB, PARP-1
and interleukin 12-dependent mechanism M. Kassan, K. Ait
Aissa, B. Haynes, M. Fontana, A. Dobrian, S. wohlgemuth,
M. Trebak, S. Belmadani and K. Matrougui. Eastern Virginia
Med. Sch., Santara Norfolk Gen. Hosp. and Univ. at Albany.
A103 1076.8 Chromium inhibits phenotypic switching of
vascular smooth muscle cells in response to hyperglycemic
conditions in vitro R. Ganguly, S. Sahu, B. Boyer and P.
Raman. Northeast Ohio Med. Univ.
1077.VASCULAR SMOOTH MUSCLE III
Poster
A104 1077.1 LRRC26 is a functional auxiliary γ subunit for
BKCa channels in arterial smooth muscle cells K.W. Evanson,
J.P. Bannister, M.D. Leo and J.H. Jaggar. Univ. of Tennessee
Hlth. Sci. Ctr.
A105 1077.2 Interaction between the Cl- conductance
associated proteins bestrophins and TMEM16A? C. Aalkjaer,
V.S. Dam, D.M. Boedtkjer and V. Matchkov. Aarhus Univ.,
Denmark.
A106 1077.3 CaV3.2 knockout mice display enhanced
myogenic tone due to reduced BKCa-mediated feedback O.F.
Harraz, S.E. Brett, S.M. Wilson and D.G. Welsh. Univ. of
Calgary, Canada and Loma Linda Univ.
A107 1077.4 Intravascular pressure stimulates functional
KV1.5 surface expression in mesenteric artery smooth muscle
cells M.W. Kidd, M.D. Leo, D. Narayanan, J.P. Bannister and
J.H. Jaggar. Univ. of Tennessee Hlth. Sci. Ctr.
A108 1077.5 Expression and function of BK and Kv1.5
channels in aortic smooth muscle from lean and obese Zucker
rats T.S. Rottgen, I.S. Fancher and G.M. Dick. West Virginia
Univ.
A109 1077.6 KCNA5 knockout mice demonstrate that Kv1.5
is a component of the native delayed rectifier K+ current in
vascular smooth muscle I.S. Fancher and G.M. Dick. West
Virginia Univ.
A110 1077.7 Arterial smooth muscle cells express segment
a-deficient TMEM16A channels S. Burris, W. Jangsangthong,
M.D. Leo, D. Narayanan and J.H. Jaggar. Univ. of Tennessee,
Memphis.
A111 1077.8 The effect of substrate elasticity on the adhesion
and elasticity of vascular smooth muscle cells Z. Hong, M. Jin,
F. Bunyak, I. Ersoy, Z. Sun, Z. Li, K. Palaniappan and G.A.
Meininger. Univ. of Missouri-Columbia.
A112 1077.9 Calcification in vitro: experimental factors
that induce nanocrystal formation L. Hortells, C. Sosa, Á.
Millán and V. Sorribas. Univ. of Zaragoza and CSIC-Univ. of
Zaragoza, Spain.
A113 1077.10 Enhancement of dynein-mediated autophagosome trafficking and autophagy maturation by ROS in
mouse coronary arterial myocytes M. Xu, X. Li, Y. Chen, Y.
Zhang and P-l. Li. Virginia Commonwealth Univ.
1078.CLUES FOR NEW THERAPEUTIC TARGETS
FOR DIABETIC CARDIOMYOPATHY
Poster
A114 1078.1 Cardiomyocyte Ogt is essential for maintaining
cardiac function A.M. DeMartino, L.J. Watson, B.W. Long,
K.R. Brittian, R.D. Readnower, R.E. Brainard, T.D. Cummins,
L.M. Annamalai, B.G. Hill and S.P. Jones. Univ. of Louisville.
A115 1078.2 Mitochondrial calcium is decreased by high
glucose and is improved by reduction of protein O-GlcNAcylation
in cardiac myocytes J.A. Diaz Juarez, J. Suarez, B.T. Scott
and W.H. Dillmann. UCSD and Natl. Cardiol. Inst., Mexico
City.
A116 1078.3 A systematic review of fetal genes as
biomarkers of cardiomegaly in rodent models of diabetes E.J.
Cox and S.A. Marsh. Washington State Univ.
A117 1078.4 Reduction of fibrosis in type 2 diabetes by
(-)-epicatechin L. Peltekian, A. Brito and K. Yamazaki.
California State Univ. Los Angeles.
A118 1078.5 mTOR inhibition protects diabetic heart against
ischemia/reperfusion injury through STAT3 activation A. Das,
F.N. Salloum, D. Durrant, A. Samidurai and R.C. Kukreja.
359
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PHYSIOLOGYTUESDAY
A119 1078.6 miR-133a ameliorates cardiac dysfunction in
diabetes: possibly by restoring β-adrenergic receptor function
and expression S.S. Nandi, X. Liu, H. Zheng, N.M. Sharma,
V. Chavali, K.P. Patel and P.K. Mishra. Univ. of Nebraska
Med. Ctr.
A120 1078.7 Cardiac responses to GLP-1 receptor
activation are impaired in the setting of metabolic syndrome
A.M. Conteh, A.G. Goodwill, J.N. Noblet, D.J. Sassoon, J.D.
Tune and K.J. Mather. Indiana Univ. Sch. of Med.
A121 1078.8 Targeted glyoxalase-1 gene transfer to prevent
cardiac dysfunction in diabetes K.R. Bidasee, F. Alomar, G.J.
Rozanski and J. Singh. Univ. of Nebraska Med. Ctr. and Univ.
of Central Lancashire, U.K.
A122 1078.9 Calcium alternans induced by enhanced
dephosphorylation of phospholamban predisposes to
inducibility of ventricular tachycardia in the type I diabetic Akita
mouse H. Jin, M. Rajab, M. Aronovitz, B. Wang, H-J. Park,
M. Link, S.F. Noujaim and J.B. Galper. Molec. Cardiol. Res.
Inst., Boston.
A123 1078.10 A pharmacologic activator of endothelial KCa
channels improves coronary function in the hearts of type
2 diabetic rats R.C. Mishra, H. Wulff, W.C. Cole and A.P.
Braun. Univ. of Calgary, Canada and Univ. of California, Davis.
A124 1078.11 The role of the VEGF/eNOS signaling pathway
in cardiovascular development: a novel target to advance
cardiovascular regeneration C. Gentile, C.G. dos Remedios,
C.J. Drake and M.J. Davies. Univ. of Sydney, The Heart Res.
Inst., Newtown, Australia and Med. Univ. of South Carolina.
A125 1078.12 High-density lipoprotein modulates glucose
metabolism in cardiomyocytes A.L. Siebel, S.E. Heywood,
D.C. Henstridge, A.L. Carey, L.M. Delbridge and B.A.
Kingwell. Baker IDI Heart & Diabetes Inst., Melbourne and
Univ. of Melbourne.
1079.WIGGERS AWARD POSTER SESSION:
MECHANISMS OF LOCAL REGULATION OF
BLOOD FLOW
Poster
A126 1079.1 TRPA1 mediates NADPH oxidase-dependent
cerebral artery dilation M.N. Sullivan, A.L. Gonzales, A.
Bruhl, M.D. Leo, J.H. Jaggar, D.G. Welsh and S. Earley.
Colorado State Univ., Univ. of Vermont, Univ. of Tennessee
Hlth. Sci. Ctr., Univ. of Calgary, Canada and Univ. of Nevada
Sch. of Med., Reno.
A127 1079.2 IGF-1 deficiency impairs cerebral myogenic
autoregulation in hypertensive mice P. Toth, Z. Tucsek, S.
Tarantini, D. Sosnowska, T. Gautam, M. Mitschelen, A.
Koller, W.E. Sonntag, A. Csiszar and Z. Ungvari. Univ. of
Oklahoma Hlth. Sci. Ctr. and Med. Sch. and Szentágothai Res.
Ctr., Univ. of Pecs, Hungary.
A128 1079.3 Dysregulation of pressure-induced Ca2+
signaling and myogenic constriction of cerebral arteries in
aged hypertensive mice P. Toth, A. Csiszar, Z. Tucsek, D.
Sosnowska, T. Gautam, A. Koller, M.L. Schwartzman, W.
Sonntag and Z. Ungvari. Univ. of Oklahoma Hlth. Sci. Ctr.,
Univ. of Pecs, Hungary and New York Med. Col.
360
A129 1079.4 Low glucose-induced mitochondrial dysfunction
enhances hypoxia-reoxygenation injury in brain microvascular
endothelial cells P.V. Katakam, D. Liu, A.O. Gordon, S. Dutta,
V.N. Sure, I. Rutkai and D.W. Busija. Tulane Univ. Sch. of
Med.
A130 1079.5 Mitochondrial depolarization of perivascular
nerves induces cerebral vasodilation by neuronal nitric oxide
synthase activation P.V. Katakam, S. Dutta, S.M. Grovenburg,
A.O. Gordon, V.N. Sure, I. Rutkai and D.W. Busija. Tulane
Univ. Sch. of Med.
A131 1079.6 Aging exacerbates hypertension-induced
intracerebral microbleeds in mice S. Tarantini, P. Toth, D.
Sosnowska, T. Gautam, Z. Tucsek, A. Koller, W.E. Sonntag,
A. Csiszar and Z. Ungvari. Univ. of Oklahoma Hlth. Sci. Ctr.
and Univ. of Pecs, Hungary.
A132 1079.7 Aging impairs myogenic adaptation to pulsatile
pressure in mouse cerebral arteries Z. Springo, P. Toth, S.
Tarantini, Z. Tucsek, P. Cseplo, A. Koller, W.E. Sonntag,
A. Csiszar and Z. Ungavri. Univ. of Oklahoma Hlth. Sci. Ctr.,
Univ. of Pecs, Hungary, and New York Med. Col.
A133 1079.8 Modulation of pressure-dependent cerebral
arterial myogenic tone by a redox-sensitive signaling event D.
Gebremedhin and D.R. Harder. Med. Col. of Wisconsin.
A134 1079.9 Qualitative differences in reflex vagal control
do exist controlling regional coronary flow resistance within
and between mammalian species S.W. White, M. Hamut, D.
Cottee and A. Quail. Univ. of Newcastle and Hunter Med. Res.
Inst., New Lambton Hgts., Australia.
A135 1079.10 Mechanism of inhibition of delayed rectifier
K+ current by diphenyl phosphine oxide-1 in porcine coronary
smooth muscle I.S. Fancher, J.N. Noblet, A.G. Goodwill, J.D.
Tune and G.M. Dick. West Virginia Univ. and Indiana Univ.
Sch. of Med.
A136 1079.11 Coronary arterial wave form relates to
compression of intramural vasculature controlled by left
ventricular end diastolic pressure J. Spaan, C. Rolandi, E.
Wiegerinck, J. Piek, J. Baan and M. Siebes. Acad. Med. Ctr.,
Amsterdam.
A137 1079.12 Innate collateral vessels in the absence of
ischemia undergo shear stress similar to normal arterial
segments of the same diameter J. Spaan, P. van Horssen, T.
Sochi, N. Smith, M. Siebes and J. van den Wijngaard. Acad.
Med. Ctr., Amsterdam and Kings Col.
A138 1079.13 Neural programming of vascular maturation
and effects of denervation J.J. Reho, X. Zheng, J.E. Benjamin
and S.A. Fisher. Univ. of Maryland Baltimore.
A139 1079.14 Defective endothelial connexin40 raises blood
pressure in mice through impairment to conducted dilation S.K.
Morton, L. Howitt, B. Baillie, J. Heisler, B.J. Nicholson, K.
Lau, A. Ashton, K.I. Matthaei and C.E. Hill. John Curtin Sch.
of Med. Res., Australian Natl. Univ., Univ. of Texas Hlth. Sci.
Ctr. at San Antonio and Royal North Shore Hosp., Univ. of
Sydney.
A140 1079.15 Connexin 37 and KCa3.1 contribute to P2Y2
receptor initiated endothelial-derived hyperpolarization M.
Sharik, J. Burt, P. Ruth and T. Rieg. VA San Diego Healthcare
Syst., Univ. of Arizona, Univ. of Tübingen and UCSD.
A141 1079.16 Nerve-evoked contraction of isolated resistance
arteries is modulated by protease-activated receptors R. Wei,
M. Zwozdesky, M. Chen, F. Plane and P.M. Kerr. Univ. of
Alberta and MacEwan Univ., Canada.
TUESDAYPHYSIOLOGY
A142 1079.17 Functional hyperemia requires ATP-sensitive
potassium channels and hydrogen peroxide and not adenosine
in isolated mice hearts X. Zhou, B. Teng and S.J. Mustafa.
West Virginia Univ.
A143 1079.18 Sympathetic escape in a theoretical model of
microvascular flow regulation T.K. Roy and T.W. Secomb.
Mayo Clin. and Univ. of Arizona.
A144 1079.19 Pannexin1 channel-mediated ATP release
and the vasodepressor response to hypoxia B.S. Kirby, B.K.
Petkov, H. Zhu and T.J. McMahon. Duke Univ.
A145 1079.20 Contribution of vascular hyperpolarization to
augmented skeletal muscle hyperemia during hypoxic exercise
in humans M.L. Racine, A.R. Crecelius, D.G. Larson, G.J.
Luckasen and F.A. Dinenno. Colorado State Univ. and Univ.
of Colorado Hlth., Loveland.
A146 1079.21 Impact of age and body position on the
contribution of nitric oxide to femoral artery shear rate:
implications for atherosclerosis J.D. Trinity, H.J. Groot, G.
Layec, M.J. Rossman, S.J. Ives and R.S. Richardson. VA
Med. Ctr. Salt Lake City and Univ. of Utah.
A147 1079.22 Activators of endothelial calcium-activated
potassium channels enhance the availability of NO released
in response to shear stress S. Lunn, N. Govindasamy, M.
Zwozdesky, R. Wei, A. Liew, P.M. Kerr and F. Plane. Univ. of
Alberta and MacEwan Univ., Canada.
A148 1079.23 Local metabolic and feed forward regulation of
coronary blood flow R.K. Pradhan, D.A. Beard, M.W. Gorman
and E.O. Feigl. Univ. of Michigan and Univ. of Washington.
A149 1079.24 Structural remodeling of coronary resistance
arteries: effects of age and exercise training M.S. Hanna, C.R.
Taylor, B. Chen, H-S. La, J.J. Maraj, C.R. Kilar, B.J. Behnke,
M.D. Delp and J.M. Muller-Delp. Univ. of Florida and Stanford
Univ.
A150 1079.25 Cardiac
myofilament
Caa,
Sup>2+
sensitization disturbs regulation of coronary flow and leads
to focal myocardial ischemia and arrhythmias during stress
S. Huke, S. Bennuri, T. Faria and B. Knollmann. Vanderbilt
Univ.
A151 1079.26 The heart as an endocrine source of metabolic
vasodilators P.T. Kang, C-L. Chen, V. Ohanyan, I. Bratz, J.G.
Meszaros, W.M. Chilian and Y-R. Chen. Northeast Ohio Med.
Univ.
A152 1079.27 Coronary microvascular dysfunction leads
to cardiac dysfunction and development of transient apical
ballooning V. Ohanyan, L. Yin, J. Luli, M. Enrick, K. Stevanov,
C.L. Kolz, S. Logan and W. Chilian. Northeast Ohio Med.
Univ.
1080.MYOCARDIAL ISCHEMIA/MYOCARDIAL
METABOLISM I
Poster
A153 1080.1 Thymoquinone protects against myocardial
ischemia-reperfusion injury via modulation of oxidant
generation and nuclear factor-kappaB-mediated responses
M.A. El-Mahdy, R.S. Ismail, C. Hemann, G.A. El-Sherbiny,
T.M. Abdelghany, G.K. Helal and J.L. Zweier. The Ohio State
Univ., Al-Azhar Univ., Col. of Pharm. and Kafrelsheikh Univ.,
Col. of Pharm., Egypt.
A154 1080.2 Hypoxia inducible factor-1 alpha contributes
to infarct size-limiting effect of postconditioning afforded by
epoxyeicosatrienoic acid analog in rat hearts. J. Neckar, A.
Hsu, A.H. Khan, G.J. Gross, J.R. Falck and J.D. Imig. Med.
Col. of Wisconsin and Univ. of Texas Southwestern Med. Ctr.
A155 1080.3 Adaptation to chronic hypoxia improves
cardiac ischemic tolerance in spontaneously hypertensive
rats J. Neckar, I. Brabcova, R. Weissova, P. Zajickova, P.
Mandikova, J. Silhavy, J. Zurmanova, O. Novakova, M.
Kalous, M. Pravenec and F. Kolar. Inst. of Physiol., Acad. of
Sci. of Czech Republic and Charles Univ. in Prague Fac. of Sci.
A156 1080.4 Combination therapy of vagal nerve stimulation
and left ventricular assist device maximally reduces the infarct
size in ischemia reperfusion model T. Kakino, K. Saku, T.
Sakamoto, T. Akashi, T. Arimura, A. Nishizaki, Y. Oga, T.
Kishi, T. Ide and K. Sunagawa. Kyushu Univ.
A157 1080.5 Reperfusion but not ischemia initiates ERS
and inhibition of ERS protects the heart from reperfusion injury
Z. Xu and J. Xi. Tianjin Med. Univ., China.
A158 1080.6 microRNA-21 mediates hydrogen sulfideinduced protection against ischemia/reperfusion injury in
diabetic heart R.A. Ockaili, A. Das, D. Durrant, C. Yin, R.C.
Kukreja and F.N. Salloum. Virginia Commonwealth Univ.
A159 1080.7 Combinational effects of apocynin and
mitoquinone in reducing myocardial ischemia/ reperfusion
injury W. Chau, R. Ondrasik, I. Devine, H. Patel, M. Lepera,
Q. Chen, R. Barsotti and L. Young. Philadelphia Col. of
Osteo. Med.
A160 1080.8 Combinational effects of gp91 ds-tat and SS31 in reducing myocardial/ischemia reperfusion injury H. Patel,
S. Walker, W. Chau, I. Devine, R. Ondrasik, Q. Chen, R.
Barsotti and L. Young. Philadelphia Col. of Osteo. Med.
A161 1080.9 Improving
survival
with
cytoprotective
therapeutics administered after a myocardial infarction in the
absence of reperfusion M.J. Platt, S. Henry, J. Huber, S.
Lutchmedial, K. Brunt and J.A. Simpson. Univ. of Guelph,
New Brunswick Heart Ctr., Dalhousie Med. New Brunswick
and Dalhousie Univ., Canada.
A162 1080.10 Targeting inflammatory serine proteases
for cardiac repair after Ischemia Reperfusion injury B.
Hooshdaran, M. Kolpakov, K. Rafiq, X. Guo, M. Kiani and
A. Sabri. Temple Univ.
1081.THIN AND THICK FILAMENT REGULATION OF
CARDIAC SARCOMERE
Poster
A163 1081.1 The R403Q mutation alters isometric and
energetic properties in 2 month mice C. Birch and J. Konhilas.
Univ. of Arizona.
A164 1081.2 Mechanisms that regulate PKCδ-dependent
phosphorylation of cardiac troponin I: the role of the C2 domain
and ATP-binding loop phosphorylation S357 S.F. Steinberg, J.
Gong, Y. Yao, P. Zhang and J. Van Eyk. Columbia Univ. and
Johns Hopkins Sch. of Med.
A165 1081.3 The energy regulating upstream kinase
complex LKB1/MO25/STRAD is a potential novel regulator
of thin filament function S. Behunin, M. Lopez-Pier and J.
Konhilas. Univ. of Arizona.
361
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A166 1081.4 Levosimendan preserves systolic and diastolic
function in rats with volume overload heart failure through
myofilament Ca2+ sensitization and regulatory protein
phosphorylation K. Lewis, T.A. West, X. Zhang, A.J. Trask,
M.J. Cismowski, P.P. de Tombe, S. Sadayappan and P.A.
Lucchesi. Nationwide Children’s Hosp., The Ohio State Univ.
and Loyola Univ. Chicago, Maywood.
A167 1081.5 Protein kinase C-site phosphorylation of
cardiac myosin binding protein-C decreases cross-bridge
kinetics S. Govindan, Y. Ait Mou, T. Lynch, P.P. de Tombe
and S. Sadayappan. Loyola Univ. Chicago, Maywood.
1082.KALEY LECTURE COMPLEMENTARY TALKS
POSTERS
1084.BLOOD PRESSURE AND FLUID VOLUME
REGULATION IN PREGNANCY AND
DEVELOPMENTAL PROGRAMMING
Poster
Poster
A168 1082.1 Microvascular mechanisms of age-related
cognitive decline Z. Ungvari, P. Toth, Z. Tucsek, D.
Sosnowska, T. Gautam, M. Mitschelen, S. Tarantini, F. Deak,
A. Koller, W.E. Sonntag and A. Csiszar. Univ. of Oklahoma
Hlth. Sci. Ctr. and Univ. of Pecs, Hungary.
A169 1082.2 Oxidative stress-induced changes in nitric oxide
availability contribute to increased pulmonary microvascular
tone in a mouse model of Alzheimer’s disease A.M. Roberts, R.
Jagadapillai, R.A. Vaishnav, R.P. Friedland, L.R. Sachleben
and E. Gozal. Univ. of Louisville.
A170 1082.3 Peroxynitrite disrupts endothelial caveolae
leading to eNOS uncoupling and diminished flow-mediated
dilation in coronary arterioles of diabetic patients Z. Bagi, A.
Feher and J. Cassuto. Georgia Regents Univ.
A171 1082.4 Renal denervation prevents dendritic cell
activation and renal T cell activation in mice in angiotensin
II-induced hypertension L. Xiao, A. Kirabo, J. Wu and D.G.
Harrison. Vanderbilt Univ.
1083.SEX DIFFERENCE IN BLOOD PRESSURE AND
FLUID VOLUME HOMEOSTASIS
Poster
A172 1083.1 Interleukin-15 contributes to decidual natural
killer cell loss via interferon-γ during early pregnancy in the
pre-eclamptic BPH/5 mouse model J.L. Sones, H.E. Lob, C.E.
Isroff, J. Song, E. Williamson and R.L. Davisson. Cornell
Univ. and Weill Cornell Med. Col.
A173 1083.2 Inhibition of endoplasmic reticulum stress does
not alter blood pressure in adult male and female spontaneously
hypertensive rats G.R. Crislip, E. Williams, A.J. Tipton and
J.C. Sullivan. Georgia Regents Univ.
A174 1083.3 Female spontaneously hypertensive rats have
a compensatory increase in renal regulatory T cells in response
to elevated blood pressure A. Tipton, B. Li and J. Sullivan.
Georgia Regents Univ. and Univ. of California, Merced.
A175 1083.4 Sex differences in bone mineral density of
the STE20/SPS1-related proline/alanine-rich kinase (SPAK)
targeted hypotensive mouse model of Gitelman syndrome
K. Siew, M. Glover and K.M. O’Shaughnessy. Univ. of
Cambridge.
362
A176 1083.5 Lack of a sex difference in leptin-mediated
regulation of appetite, cardiovascular function and glucose
homeostasis A.A. da Silva, M.A. Pinkerton, F.T. Spradley,
A.C. Palei and J.M. do Carmo. Univ. of Mississippi Med. Ctr.
A177 1083.6 The influence of estrogen on circadian rhythms
of heart rates and cardiac sympathetic nerve in female rats
S. Marui, M. Matsuda, N. Sato and K. Nagashima. Waseda
Univ., Japan.
A178 1084.1 Pregnant rats treated with a high fat/pro-oxidant
western diet with angiotensin II and tumor necrosis factor α
are resistant to elevations in blood pressure (BP) and have the
normal fall in BP during late pregnancy M.W. Cunningham,
C.A. West and C. Baylis. Univ. of Florida Col. of Med.
A179 1084.2 Obese melanocortin-4 receptor-deficient rats
exhibit attenuated adrenergic vasoconstriction F.T. Spradley,
A.C. Palei and J.P. Granger. Univ. of Mississippi Med. Ctr.
A180 1084.3 Antiphospholipid
antibodies,
necrotic
trophoblasts and preeclampsia? S.Y.S. Lau, Q. Chen, L.
Chamley, C. Barrett and S-J. Guild. Univ. of Auckland.
A181 1084.4 Co-releasing molecules attenuate placental
ischemia-induced hypertension in pregnant rats E.M. George,
D.E. Stec and J.P. Granger. Univ. of Mississippi Med. Ctr.
A182 1084.5 A reduction in uterine perfusion pressure
induces hypertension during pregnancy in the mouse S.
Intapad, J.P. Warrington, F.T. Spradley, A. Palei, H.E.
Drummond, M.J. Ryan, J.P. Granger and B.T. Alexander.
Univ. of Mississippi Med. Ctr.
A183 1084.6 The role of TNF alpha in placental ischemiainduced cerebrovascular abnormalities J.P. Warrington, H.A.
Drummond, M.J. Ryan and J.P. Granger. Univ. of Mississippi
Med. Ctr.
A184 1084.7 Complement
C5a
receptor
antagonist
attenuates placental ischemia-induced hypertension in rat J.M.
Peterson, K.E. Lillegard, B.J. Elmquist, J.S. Gilbert and
J.F. Regal. Univ. of Minnesota Med. Sch. Duluth and Univ. of
Oregon.
A185 1084.8 Antagonism of complement C5a receptor
but not C3a receptor attenuates placental ischemia-induced
endothelial dysfunction in rat J.W. Opacich, A.C. Johnson,
A.J. Bauer, J.S. Gilbert and J.F. Regal. Univ. of Minnesota
Med. Sch. Duluth and Univ. of Oregon.
A186 1084.9 Exercise before and during pregnancy
does not lower blood pressure in an sFlt-1 infusion model
of preeclampsia in the rat C.T. Banek, H.E. Gillham, K.W.
Needham, S.M. Johnson, K.M. Beasley and J.S. Gilbert.
Univ. of Oregon.
A187 1084.10 Thermal stress conditions endothelial cells and
improves cellular function K. Needham, S.F. Macrorie, C.T.
Minson and J.S. Gilbert. Univ. of Oregon.
A188 1084.11 Complement components C3a and C5a alter
angiogenic balance in placental and endothelial cells H.E.
Gillham, C.T. Banek, K.W. Needham, J.F. Regal and J.S.
Gilbert. Univ. of Oregon and Univ. of Minnesota Med. Sch.,
Duluth.
TUESDAYPHYSIOLOGY
A189 1084.12 Prevention of ischemic vascular injury: targeting
cellular stress in the endothelium with 5-aminoimidazole4-carboxamide 1-β-D-ribofuranoside S.M. Johnson, C.T.
Banek, H.E. Gillham, K.W. Needham and J.S. Gilbert. Univ.
of Oregon.
1085.DEVELOPMENTAL ORIGINS OF METABOLIC
AND CARDIOVASCULAR DISEASE
Poster
A190 1085.1 A new model of intrauterine growth restriction
(IUGR) induced by reduced uterine perfusion in the mouse
programs hypertension in the IUGR mouse offspring S.
Intapad. Univ. of Mississippi Med. Ctr.
A191 1085.2 Blockade of the renin angiotensin system
abolishes age-dependent hypertension in female intrauterine
growth restricted rats in the absence of an enhanced sensitivity
to acute angiotensin II S. Intapad, J.H. Dasinger, M.A.
Backstrom and B.T. Alexander. Univ. of Mississippi Med. Ctr.
A192 1085.3 Early life stress induces circulating factor(s)
promoting endothelial dysfunction D.H. Ho, M.L. Burch, B.C.
Musall and J.S. Pollock. Georgia Regents Univ.
A193 1085.4 Maternal western diet primes non-alcoholic
fatty liver disease in adult offspring in mice T. Plosch, M. Pruis,
A. Lendvai, M.V. Zwier, A. de Bruin and A.K. Groen. Univ.
Med. Ctr. Groningen and Utrecht Univ., Netherlands.
A194 1085.5 AT1 receptor blockade abolishes metabolic
and cardiovascular programming effects of neonatal obesity
and undernutrition A.S. Mecawi, P.B. Marangon, D.J. Moraes,
L.G. Bonagamba, B.H. Machado, L.L. Elias and J. AntunesRodrigues. Sch. of Med. of Ribeirão Preto, Univ. of São Paulo.
A195 1085.6 Sex specific effect of antenatal glucocorticoids
on nitric oxide production stimulated by angiotensin peptides in
renal proximal tubule cells J. Bi, K. Chen, Y. Su, M. Chappell
and J.C. Rose. Wake Forest Sch. of Med.
A196 1085.7 High fat feeding induces exaggerated
endothelial dysfunction and insulin resistance in rats exposed
to maternal separation A.S. Loria, B. Fox, D.M. Pollock and
J.S. Pollock. Georgia Regents Univ.
A197 1085.8 Vascular dysfunction, arterial hypertension
and insulin-resistance in offspring of a mouse model of
preeclampsia: prevention by sildenafil D. Cerny, E. Rexhaj, E.
Bouillet, R. Soria, C. Sartori, Y. Allemann, S. Rimoldi and U.
Scherrer. Univ. Hosp. Berne.
A198 1085.9 Reduced uterine perfusion pressure alters
angiogenic balance in the amniotic fluid and fetal lung of the
rat A.A. Rear, K.W. Needham, A.T. Lovering, J.F. Regal and
J.S. Gilbert. Univ. of Oregon and Univ. of Minnesota Duluth.
A199 1085.10 Age impacts the developmental programming
of blood pressure regulation in the intrauterine growth-restricted
male rat J.H. Dasinger, S. Intapad, M.A. Backstrom and B.T.
Alexander. Univ. of Mississippi Med. Ctr.
A200 1085.11 Early life stress enhances renal expression of
T-cell and B-cell activation factors I. Obi, D. Ho, A. Loria and
J. Pollock. Georgia Regents Univ.
A201 1085.12 Chronic placental ischemia alters expression
of placental and fetal insulin-like growth factor proteins in the
rat K. Beasley, K. Needham, J.F. Regal, A. Lovering and J.
Gilbert. Univ. or Oregon and Univ. of Minnesota Med. Sch.Duluth.
1086.CARDIOVASCULAR AND RENAL MECHANISMS
IN DIABETES AND METABOLIC SYNDROME
Poster
A202 1086.1 Synergy of high salt and high fat diet on kidney
injury and adiposity C. Jin, R.T. MacDonell, J.S. Speed and
D.M. Pollock. Georgia Regents Univ.
A203 1086.2 The diverse mechanisms of cardiomyopathy
and heart failure in obese and non-obese insulin-resistant
rat models J-P. Huang and L-M. Hung. Chang Gung Univ.,
Taiwan.
A204 1086.3 ENaC-independent impaired natriuresis and
increased blood pressure in mouse models of diet-induced
hyperinsulinemia J. Nizar, W. Dong, R. McClellan, M.
Labarca, Y. Zhou, L. Satlin and V. Bhalla. Stanford Univ.,
Univ. of South Alabama and Mount Sinai Sch. of Med.
A205 1086.4 Autonomic and metabolic changes induced by
fructose overload: role of baroreflex F. Santos, E.D. Moreira,
M. Sartori and M.C. Irigoyen. Med. Sch. of São Paulo Univ.
A206 1086.5 Effects of epicatechin on glucose transporters
in cardiac tissue and peripheral nerves in type 2 diabetes N.
Gonzalez. California State Univ., Los Angeles.
A207 1086.6 Suppression of cardio-protective molecules
by diabetic marker miR-29: a mechanism for the high rate of
cardiac damage in diabetes? N. Arnold, P. Koppula and L.
Pulakat. Univ. of Missouri-Columbia.
A208 1086.7 Endoplasmic reticulum stress contributes
coronary artery dysfunction in type 2 diabetic mice S-K. Choi
and Y-H. Lee. Yonsei Univ. Col. of Med., South Korea.
A209 1086.8 Hyperglycemia-driven glycosylation of the AT1
receptor in the vascular endothelium B.R. Hoffmann, A.R.
Prisco and A.S. Greene. Med. Col. of Wisconsin.
1087.DEVELOPMENTAL PROGRAMMING AND
CARDIORENAL FUNCTION IN ADULTS
Poster
A210 1087.1 Prenatal taurine supplementation decreases
adult renal function by mechanisms other than taurine inhibition
of prenatal renin-angiotensin system S. Roysommuti, A.
Kritsongsakchai and J.M. Wyss. Fac. of Med., Khon Kaen
Univ., Thailand, Fac. of Med., Naresuan Univ., Thailand and
Univ. of Alabama at Birmingham.
A211 1087.2 Salt intake during pregnancy influences
offspring organ growth M.A. Peres, I.B. de Oliveira, L.N.
Furukawa, C.F. Guimarães and J.C. Heimann. Univ. of São
Paulo Sch. of Med.
A212 1087.3 Resistance arteries from normally-reared and
maternal separation rats display similar vascular reactivity
B.M. Fox, A.S. Loria and J.S. Pollock. Georgia Regents Univ.
363
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PHYSIOLOGYTUESDAY
1088.RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM
IN REGULATION OF BLOOD PRESSURE AND
RENAL FUNCTION
Poster
A213 1088.1 Changes in vascular reactivity caused by
angiotensin II in heart resistance vessels and isolated vessels
of rat aorta in a model of hypertension E. Lopez-Calderon,
N. Acevedo-Villavicencio, G. Guevara-Balcazar, E. HongChong and M.C. Castillo-Hernandez. Sch. of Med., Natl.
Polytech Inst. and CINVESTAV, Mexico City.
A214 1088.2 Nucleic acid binding of annexin A2 is regulated
through angiotensin II/AT1 signaling in kidneys of hypertensive
rats M. Hultström, A. Paliege, T. Skogstrand and M. Fähling.
Uppsala Univ., Charité, Berlin and Univ. of Bergen, Norway.
A215 1088.3 Adaptation of chronic renal microdialysis
to evaluate the role of interstitial ATP and angiotensin II
in accelerating nephropathy and oxidative stress during
insulin induced hypertension P. Prathipati, W. Alanazi, F.
Fakhruddin, D.W. Jackson and K.E. Jackson. Univ. of
Louisiana at Monroe.
A216 1088.4 Molecular mechanisms associated to reversion
of proteinuria by RAS antagonists in renovascular hypertensive
rats J.W.N. Correa, A.C. Girardi, T.A. Salles, K.R. Boaro, F.P.
Loredo, A. Yogi, G.E. Callera, R.M. Touyz, L.M. Bendhack
and J.E. Krieger. Fed. Univ. of Manaus, Brazil, Univ. of São
Paulo and Univ. of Ottawa.
A217 1088.5 Combination therapy of olmesartan/exenatide
decreases renal ER stress in a rat model of metabolic syndrome
S. Duval Ruilova, C. De Miguel, R.M. Ortiz and J. Pollock.
Univ. of California, Merced and Georgia Regents Univ.
A218 1088.6 Natriuretic responses to angiotensin 1-7
infusion in hypertensive rat models E.F. Barry and E. Johns.
University Col. Cork.
A219 1088.7 Relationship between renal Ang (1-7) induced
sodium and water excretion and AT2 receptors J. O’Neill and
E.J. Johns. University Col. Cork.
A220 1088.8 Glucagon-like peptide 1 receptor activation
acutely increases systolic blood pressure independent of
aldosterone-mediated sodium retention M. Moreno, R.
Rodriguez, A. Lee, G. Vazquez, S.D. Ruilova and R.M. Ortiz.
Univ. of California, Merced.
A221 1088.9 Functional neprilysin-angiotensin-(1-7) system
within mitochondria of the sheep kidney B.A. Wilson, J.C.
Rose and M.C. Chappell. Wake Forest Sch. of Med.
A222 1088.10 Expression
of
an
angiotensin-(1-7)
endopeptidase in proximal tubules of the sheep and human
kidney B.A. Wilson, A.C. Marshall, N.T. Pirro, Y. Su, J.C.
Rose and M.C. Chappell. Wake Forest Sch. of Med.
A223 1088.11 Plasmalemmal lipid rafts are required for
signal transduction by AGTR1 in neonatal mesangial cells A.
Adebiyi, H. Soni, T.A. John and F. Yang. Univ. of Tennessee
Hlth. Sci. Ctr.
A224 1088.12 Role of Src homology 2 domain-containing
protein B in the regulation of GFR and renal afferent arteriole
responsiveness X. Gao, J. Sällström, Z. Ma, M. Welsh and
A.E.G. Persson. Uppsala Univ., Karolinska Inst. and Tongji
Hosp., Wuhan, China.
364
A225 1088.13 Effects of long-term aldosterone administration
on mRNA expression levels in the renal distal nephron
examined by FACS and RNA sequencing S.B. Poulsen, J.
Praetorius, R.A. Fenton and B.M. Christensen. Aarhus
Univ., Denmark.
A226 1088.14 Coordinated regulation of ENaC activity in the
distal nephron by aldosterone and Ang II M. Mamenko, O.
Zaika, M.C. Prieto, B.V. Jensen, P.A. Doris, G.L. Navar and
O. Pochynyuk. Univ. of Texas Hlth. Sci. Ctr. at Houston and
Tulane Univ. Sch. of Med.
1089.LUNG PHYSIOLOGY: PULMONARY
HYPERTENSION
Poster
A227 1089.1 Misclassification of pulmonary hypertension
due to automated pulmonary capillary wedge pressure
calculations S. Shterental, A. Longhini, M.B. Alam, T.
Bachman, P. Corotto, S. Gupta, D. Nguyen, A.H. Shoushtari,
F. Zaidi, M. Simon and H.C. Champion. Univ. of Pittsburgh
Sch. of Med. and Univ. of Pittsburgh Med. Ctr.
A228 1089.2 Augmentation area index: a novel approach
to disease severity and outcome in patients with WHO group
I and group III pulmonary hypertension S. Shterental, M.B.
Alam, T. Bachman, P. Corotto, S. Gupta, A. Longhini, D.
Nguyen, F. Sciurba, M. Simon and H.C. Champion. Univ. of
Pittsburgh Sch. of Med. and Univ. of Pittsburgh Med. Ctr.
A229 1089.3 Changes in IgG sialylation and glycosylation in
pulmonary arterial hypertension R.L. Morrow, E.A. Cioffi, F.
Murphy and D.L. Cioffi. Univ. of South Alabama.
A230 1089.4 Augmented pulmonary artery pressure
response during exercise in adults born extremely preterm,
but not in those with bronchopulmonary dysplasia S.S. Laurie,
J.E. Elliott, K.M. Beasley, T.S. Mangum, R.D. Goodman, I.M.
Gladstone and A.T. Lovering. Johns Hopkins Univ., Univ. of
Oregon, Oregon Heart & Vasc. Inst., Springfield and Oregon
Hlth. & Sci. Univ.
A231 1089.5 Preservation of Ca2+ spark activity during
oxidative stress in pulmonary arterial myocytes of fetal sheep
G. Suarez, S.L. Glasgow, M. Romero, N. Osman, J.L.
Puglisi, D.M. Bers, L.T. Izu, L.D. Longo and S.M. Wilson.
Anaheim H.S., Loma Linda Univ. and Univ. of California, Davis.
A232 1089.6 Antenatal chronic hypoxia and L-type Ca2+dependent contractility of pulmonary arteries from fetal sheep
A. Brunelle, Q. Blood, L.D. Longo and S.M. Wilson. Loma
Linda Univ. Sch. of Med.
A233 1089.7 cGMP amplification of pulmonary arterial
myocyte Ca2+ waves is preferentially impaired in high altitudeinduced hypoxic fetal sheep R. Paez, M. Romero, Q. Blood,
N. Osman, C. Manjunath, S. Glasgow, M. Francis, M.S.
Taylor, L.D. Longo and S.M. Wilson. Loma Linda Univ. Sch.
of Med. and Univ. of South Alabama Col. of Med.
A234 1089.8 Disruption of membrane caveolae limits
pulmonary vasoconstriction induced by agonists in pulmonary
hypertension rats H-X. Jiao, Y-P. Mu, R-X. Wang, D-C. Lin,
J.S. Sham and M-J. Lin. Fujian Med. Univ., China and Johns
Hopkins Med. Instns.
TUESDAYPHYSIOLOGY
A235 1089.9 Cholesterol regulates both store- and agonistinduced Ca2+ entry in pulmonary arterial endothelium B. Zhang,
M.A. Riddle, J.S. Naik, T.C. Resta and B.R. Walker. Univ. of
New Mexico.
A236 1089.10 Newly identified caveolin-1 mutation associated
with heritable human pulmonary arterial hypertension mediates
hyperproliferation via augmented calcium signaling G.
Marsboom, K.M. Theriault, A. Debroy, M. Mao, S.M. Baig,
C. Tiruppathi, M.G. Bonini, J. Rehman, E. Austin and A.B.
Malik. Univ. of Illinois at Chicago and Vanderbilt Univ. Med. Ctr.
A237 1089.11 Oxidative stress and the impact of prenatal
chronic hypoxia on ryanodine receptor generated calcium
responses in fetal pulmonary arterial myocytes S. Kaushal, M.
Romero, N. Osman, R. Paez, M. Francis, M.S. Taylor, L.D.
Longo and S.M. Wilson. Loma Linda Univ. Sch. of Med. and
Univ. of South Alabama Col. of Med.
A238 1089.12 Enhanced endothelin-1- and depolarizationinduced pulmonary vasoconstriction following chronic hypoxia
require Src family kinases C.E. Norton, B.R. Walker and T.C.
Resta. Univ. of New Mexico.
A239 1089.13 Rosiglitazone
attenuated
endothelin-1induced vasoconstriction of pulmonary arteries in the rat model
of pulmonary arterial hypertension Y. Liu, X. Tian, Y. Huang
and N. Wang. Peking Univ. Hlth. Sci. Ctr., Sch. of Biomed. Sci.,
Chinese Univ. of Hong Kong and Xi’an Jiaotong Univ., China.
A240 1089.14 Acute hypoxia-induced endothelial-dependent
suppression of Ca2+ waves in pulmonary arterial myocytes
of sheep S. Sandy, M. Romero, R. Paez, M. Francis, M.S.
Taylor, L.D. Longo and S.M. Wilson. California Baptist Univ.,
Loma Linda Univ. Sch. of Med. and Univ. of South Alabama
Col. of Med.
A241 1089.15 Actin polymerization contributes to enhanced
pulmonary arterial vasoconstrictor reactivity following chronic
hypoxia J.R. Sheak, M.A. Sands, J.B. Snow, L.V. Gonzalez
Bosc, N.L. Jernigan, B.R. Walker and T.C. Resta. Univ. of
New Mexico.
A242 1089.16 The role of mitochondrial reactive oxygen
species in hypoxia-induced pulmonary hypertension S.E.
Adesina, C.M. Hart and R.L. Sutliff. Atlant VA/Emory Univ.
Med. Ctrs., Decateur.
A243 1089.17 Chronic hypoxia suppresses muscarinicinduced contractility in ovine pulmonary arteries M. Giang, R.
Paez, J. Kim, Q. Blood, L.D. Longo and S.M. Wilson. Loma
A244 1089.18 Chronic hypoxia increases the importance of
BKCa channels to bradykinin-mediated pulmonary vasodilation
in fetal sheep C. Blum-Johnston, C. Wee, Q. Blood, R.H.
Wilson, A.B. Blood, L.D. Longo and S.M. Wilson. Loma
A245 1089.19 Endothelium-targeted deletion of Nox4
attenuates hypoxia-induced increases in right ventricular
pressure R.L. Sutliff, J. Kleinhenz, J. Ma and C.M. Hart.
Emory Univ./Atlanta VA Med. Ctr., Decatur.
A246 1089.20 Fatal pulmonary arterial hypertension in
female Fischer 344 rats E.S. Crockett, J.M. McLendon,
A.A. Alzoubi, I.F. McMurtry and T. Stevens. Univ. of South
Alabama and Jordan Univ. of Sci. and Technol.
A247 1089.21 Phenotypic characteristics of pulmonary
supernumerary arterial endothelium may be involved in the
formation of plexiform lesions K. Oshima, Y. Matsumoto, K.
O’Neill, I.F. McMurtry, T. Stevens and M. Oka. Univ. of South
Alabama.
A248 1089.22 microRNA-301b reduces PPARγ expression in
transgenic sickle mice and in hemin-treated human pulmonary
artery endothelial cells B-Y. Kang, F. Tan, G. Samit, D.R.
Archer, R.L. Sutliff, S.F. Ofori-Acquah and C.M. Hart.
Atlanta VA and Emory Univ. Med. Ctrs., Emory Univ. and Univ.
of Pittsburgh.
A249 1089.23 Implication of miR-204/RUNX2-dependent
calcification pathway in pulmonary arterial hypertension A.
Pflieger, J. Meloche, E. Tremblay, S. Breuils-Bonnet, S.
Provencher and S. Bonnet. Quebec Heart and Lung Inst.
Rest. Ctr., Laval Univ.
1090.SIGNALING IN PULMONARY HYPERTENSION
Poster
A250 1090.1 AntimiR-145 therapy improves right ventricular
structure in experimental pulmonary arterial hypertension J.M.
McLendon, S.R. Joshi, J.G. Fewell, M. Oka, I.F. McMurtry
and W.T. Gerthoffer. Univ. of South Alabama and Egen Inc.,
Huntsville.
A251 1090.2 Mutant BMPR2 expression in cardiomyocytes
results in an altered hypertrophic response M. Talati, M. Funke,
J. Bylund, A.W. Trammell, S.M. Majka, J.P. Fessel, J. West,
J. Newman, A. Hatzopoulos and A. Hemnes. Vanderbilt Univ.
A252 1090.3 G protein-coupled receptor expression and
function in pulmonary artery smooth muscle cells: new
targets in pulmonary arterial hypertension D.S. McDonald, N.
Aroonsakool, O. Kwon, P.A. Insel and F. Murray. UCSD and
Univ. of Aberdeen, U.K.
A253 1090.4 Interleukin-33
in
pulmonary
arterial
hypertension: a role in disease pathogenesis? N. Aroonsakool,
D. Titone, J. Li, J. Dumouchel, S. Lombardi, N. Kim, D. Poch,
T. Bigby and F. Murray. UCSD, VA San Diego Healthcare
Syst. and Univ. of Aberdeen Sch. of Med. Sci.
A254 1090.5 CD4+ T cells contribute to chronic hypoxiainduced pulmonary hypertension L.D. Maston, J.L. Cannon,
T.C. Resta and L.V. González Bosc. Univ. of New Mexico.
A255 1090.6 Circulating microparticles from pulmonary
arterial hypertension stimulate ICAM-1 and E-selectin
expression in pulmonary artery endothelial cells L.A. Hargett,
K. O’Neill, T. Yarbrough and N. Bauer. Univ. of South
Alabama.
A256 1090.7 Microparticles
stimulated
by
hypoxic
pulmonary hypertension have differing effects on vascular cell
growth than microparticles from severe occlusive pulmonary
arterial hypertension T. Yarbrough and N. Bauer. Univ. of
South Alabama.
A257 1090.8 Cigarette smoke causes RV dysfunction and
cardiac fibroblast proliferation K.A. O’Connell, A. Vang, P.
Sakhatskyy, Q. Lu, S. Rounds and G. Choudhary. Brown
Univ. and Providence VA Med. Ctr.
A258 1090.9 Anti-oxidative and anti-inflammatory role of
adipose stem cells in reversing pulmonary hypertension and
associated cardiac remodeling A. Rathinasabapathy, V.
Shenoy, E. Bruce, A. Espejo, A. Nair, J. Francis, M. Raizada
and M. Katovich. Univ. of Florida and LSU.
A259 1090.10 Role of mitochondrial KATP channels in PKCβdependent constriction of small pulmonary arteries J. Snow,
C. Norton, M. Sands, N. Jernigan, L. Gonzalez Bosc, B.
Walker and T. Resta. Univ. of New Mexico.
365
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PHYSIOLOGYTUESDAY
A260 1090.11 TRPV4-associated alterations of Ca2+ pulsars
in a murine model of pulmonary hypertension secondary to
heart failure N.R. Dayeh, S. Safar, M-A. Gillis, A. Blanchette,
J. Dupuis and J. Ledoux. Univ. of Montréal and Montreal
Heart Inst.
A261 1090.12 ASIC1-dependent Ca2+ influx is required for
NFATc3 activation in chronic hypoxia-induced pulmonary
hypertension N.L. Jernigan, D.R. Plomaritas, W.
Giermakowska, L.M. Herbert, C.H. Nitta and L.V. Gonzalez
Bosc. Univ. of New Mexico Hlth. Sci. Ctr.
A262 1090.13 Shear stress enhance intracellular Ca2+ in
PASMC from patients with idiopathic pulmonary arterial
hypertension s. song, H. Tang, K.A. Smith, A. Makino and
J.X-J. Yuan. Univ. of Illinois at Chicago.
1091.GENETIC MANIPULATION IN RESPIRATORY
CONTROL: BASIC SCIENCE TO CLINICAL
TRIALS
Poster
A263 1091.1 Overexpression of HSP72 protects against
mechanical ventilation-induced mitochondrial dysfunction
and apoptotic signaling in the diaphragm A.J. Smuder, K.J.
Sollanek, K. Min, O.S. Kwon, W.B. Nelson and S.K. Powers.
Univ. of Florida.
A264 1091.2 Spinal protein phosphatase 1 constrains
respiratory plasticity after sustained hypoxia A.G. Huxtable,
T.J. Peterson, E.S. Kopp and G.S. Mitchell. Univ. of
Wisconsin-Madison.
A265 1091.3 Selective knockout of acid α-glucosidase GAA
gene expression in the medulla alters breathing D.D. Fuller,
M.K. Elmallah, H.H. Ross, A.A. Cerreta, M. Corti, B.B. Smith,
A. Poirier, R.R. Mandel and B.B. Byrne. Univ. of Florida.
A266 1091.4 vGluT2 is necessary for rostroventrolateral
medullary catecholaminergic neurons to drive respiration and
parasympathetic activity B. Holloway, S. Abbott, K. Viar and
P. Guyenet. Univ. of Virginia.
A267 1091.5 Optogenetic stimulation of adrenergic C1
neurons in rat produces arousal from sleep, sighs and
increases breathing frequency P.G. Burke, S.B. Abbott, W.M.
Hodges, K.E. Viar, M. Coates, R. Stornetta and P. Guyenet.
Univ. of Virginia.
A268 1091.6 Adeno-associated viral delivery of TrkB after
upper cervical spinal hemisection enhances recovery J.M.
Zambrano, G. Martinez-Galvez, W-Z. Zhan, H.M. Gransee,
G.C. Sieck and C.B. Mantilla. Univ. de los Andes, Colombia
and Mayo Clin. Col. of Med.
A269 1091.7 Repetitive
acute
intermittent
hypoxia
downregulates inflammatory gene expression in the rat ventral
cervical spinal cord J. Watters, A. Roopra, K. Bowen, S. Vinit,
P. Macfarlane and G. Mitchell. Univ. of Wisconsin-Madison,
Simone Veil Univ., France and Case Western Reserve Univ.
A270 1091.8 Acid alpha-glucosidase gene replacement
therapy to the diaphragm remodels ventilatory function in
severe Pompe disease B.K. Smith, D. Martin, C.S. Mah, L.A.
Lawson, D.J. Falk, D.D. Fuller, S. Islam, S.W. Collins and
B.J. Byrne. Univ. of Florida.
366
1092.CONTROL OF BREATHING: CHEMORECEPTION
Poster
A271 1092.1 Dual response to bumetanide in avian
intrapulmonary chemoreceptors P.R. Bassett, S.T. Meehan,
J-G. Lonjaret, K.L. Sheridan and S.C. Hempleman. Northern
Arizona Univ.
A272 1092.2 Model of chloride-bicarbonate countermovement
in
CO2-sensitive
avian
intrapulmonary
chemoreceptors J-G. Lonjaret, P.R. Bassett, S.T. Meehan,
K.L. Sheridan and S.C. Hempleman. Northern Arizona Univ.
A273 1092.3 KCC and NKCC activity affect spike
frequency adaptation in CO2-sensitive avian intrapulmonary
chemoreceptors S.T. Meehan, P.R. Bassett, J-G. Lonjaret,
S.C. Hempleman and K.L. Sheridan. Northern Arizona Univ.
A274 1092.4 Potential
bullfrog
homologue
to
the
chemosensitive mammalian retrotrapezoid nucleus M. Reed,
K. Iceman, M. Harris and B. Taylor. Univ. of Alaska Fairbanks.
A275 1092.5 Hyperoxia increases free radical production in
rat brain slices in the dorsal CO2-chemosensitive area of the
caudal medulla oblongata G. Ciarlone and J.B. Dean. Univ. of
South Florida.
A276 1092.6 The thyrotropin-releasing hormone analog
Taltirelin augments the hypercapnic ventilatory response in
CO2-insensitive Brown Norway but not Sprague Dawley rats
M.R. Hodges, T. Novotny, A.E. Echert, M.M. Puissant and
G.C. Mouradian. Med. Col. of Wisconsin.
A277 1092.7 Utilizing transgenic rats with eGFP-tagged
serotonergic (5-HT) neurons to assess differential gene
expression associated with age-dependent changes in cellular
CO2/H+ chemosensitivity M.M. Puissant, G.C. Mouradian,
A.M. Geurts and M.R. Hodges. Med. Col. of Wisconsin.
A278 1092.8 Numbers of pH-sensitive K+ channelimmunoreactive neurons are reduced in CO2-insensitive Brown
Norway rats in select brainstem nuclei associated with central
respiratory chemoreception P.F. Martino, S. Olesiak, D. Riley,
S. Neumueller, H.V. Forster and M.R. Hodges. Carthage
Col., Med. Col. of Wisconsin and Zablocki VA Med. Ctr.
A279 1092.9 Spike frequency adaptation in avian
intrapulmonary chemoreceptors does not rely on Na+/H+
exchange K.L. Sheridan, S.C. Hempleman, J-G. Lonjaret,
S.T. Meehan and P.R. Bassett. Northern Arizona Univ.
A280 1092.10 Ventilatory sensitivity to CO2 is altered by
external breathing resistance B. Shykoff and D. Warkander.
Navy Exptl. Diving Unit, Panama City, FL.
A281 1092.11 Minocycline prevents the attenuated acute
hypoxic ventilatory response and changes in brainstem
neurochemistry following neonatal sustained hypoxia exposure
P.M. MacFarlane and C.A. Mayer. Case Western Reserve
Univ., Rainbow Babies & Children’s Hosp.
A282 1092.12 Differential effects of neonatal sustained
hypoxia exposure on the acute hypoxic ventilatory response
among different rat strains P.M. Warren, D. Bozek, C.A. Mayer,
W.J. Alilain and P.M. MacFarlane. MetroHlth. Med. Ctr. and
Case Western Reserve Univ. and Case Western Reserve Univ.
and Rainbow Babies & Children’s Hosp.
A283 1092.13 Ventilatory chemoreflex sensitivity in sleep
apnea is decreased with high dose ascorbic acid U.A.
Leuenberger, C. Aswegen, C. Blaha and J. Mast. Penn State
Hershey Heart and Vasc. Inst.
TUESDAYPHYSIOLOGY
A284 1092.14 GAL-160 increases CO2 chemosensitivity and
reverses opioid-induced respiratory depression in rats S.M.
Baby, C.M. Ideo, S.I. Mardirosian, S.X. Peng, F.J. Golder
and D.E. MacIntyre. Galleon Pharmaceuts. Inc., Horsham,
PA.
A285 1092.15 Three-dimensional structure and association
with blood vessels of chemosensitive and nonchemosensitive
locus coeruleus neurons from neonatal rats R.W. Putnam,
C.D. Graham and K-y.W. Li. Wright State Univ.
A286 1092.16 The effects of prior hyperventilation duration
on central chemoreflex responses using the “Duffin” hyperoxic
rebreathing test L. Boulet, A. Jamieson and T.A. Day. Mount
Royal Univ., Canada.
A295 1094.5 Generation of multiciliated cells in functional
airway epithelium from human iPSC A.L. Firth, T. Menon, C.
Dargitz, S.J. Qualls, R. Wright, A. Khanna and I.M. Verma.
Salk Inst. for Biol. Studies and Cleveland Clin.
A296 1094.6 The role of Na/K-ATPase in cardiac stem cells
H. Shi, C.A. Drummond and J. Tian. Univ. of Toledo.
A297 1094.7 The role of O-linked-N-acetylglucosamine
transferase in regulating autophagy J.L. McLarty, A.J.
Paterson and J.C. Chatham. Univ. of Alabama at Birmingham.
A298 1094.8 Chronic rapamycin treatment decreases
markers of autophagy and mitophagy in a sex-specific manner
J.C. Drake, D. Bruns, R. Miller, K. Hamilton and B. Miller.
Colorado State Univ. and Univ. of Michigan.
1093.APOPTOSIS AND CELL DEATH
1095.CELL SIGNALING: PATHWAYS AND PROTEINS
Poster
Poster
A287 1093.1 GAPDH prevents oxidant-induced apoptosis
in smooth muscle cells via upregulation of APE1/Ref-1
endonuclease S. Sukhanov, T. Yoshida and P. Delafontaine.
Tulane Univ.
A288 1093.2 The role of miR-21 in propofol-induced
neurotoxicity in developing human neurons D. Twaroski, X.
Bai, J. Olson, Y. Yan, Y. Liu and Z.J. Bosnjak. Med. Col. of
Wisconsin.
A289 1093.3 High expression of CD147 in endometriosis
and its role in regulating apoptosis and migration in human
endometrial cells H. Chen, C. Wang, A. Jing, X. Zhou, Z. Cai
and H. Chan. Shenzhen Second People’s Hosp., First Affil.
Hosp. of Shenzhen Univ. and The Chinese Univ. of Hong Kong.
A290 1093.4 Bone marrow cells apoptosis in experimental
anemia T. Zaporozhets and O. Sanyk. Ukrainian Med.
Stomatol. Acad., Poltava.
1094.STEM CELLS AND CELL GROWTH,
DEVELOPMENT AND DIFFERENTIATION,
AUTOPHAGY
Poster
A291 1094.1 The promotion of osteogenic differentiation of
human adipose-derived mesenchymal stem cells induced by
chitosan-conjugated gold nanoparticles S.Y. Choi, M-S. Song,
P-D. Ryu, S-W. Joo and S.Y. Lee. Col. of Vet. Med., Seoul
Natl. Univ. and Col. of Nat. Sci., Soongsil Univ.,, South Korea.
A292 1094.2 25-Hydroxycholesterol inhibits adipogenic
differentiation of C3H10T1/2 mouse stem cells through
inhibition of PPARγ expression D.N. Moseti, A.H. Regassa
and W.K. Kim. Univ. of Manitoba and Univ. of Georgia.
A293 1094.3 LPA receptor 2 and 3 reversely regulate TPAinduced megakaryopoiesis in K562 leukemia cell line Y-H. Ho,
K-H. Lin, Y-N. Lin, M-W. Li, S-H. Lin, Y-J. Yang, C-L. Chiang,
C-L. Yao and H. Lee. Natl. Taiwan Univ., The Ohio State Univ.
and Yuan-Ze Univ., Taiwan.
A294 1094.4 Role of CFTR in embryonic stem cell
programming Z. Liu, P. Yuan, X. Jiang and H.C. Chan. The
Chinese Univ. of Hong Kong.
A313 1095.1 Lemur tyrosine kinase-2, a novel regulator of
androgen receptor signaling in prostate cancer K. Shah and
N. Bradbury. Rosalind Franklin Univ. of Med. and Sci.
A314 1095.2 Novel signaling function of hCLCA1 in airway
macrophages activation J.C. Ching and M.E. Loewen. Univ.
of Saskatchewan Western Col. of Vet. Med.
A315 1095.3 Anti-aging gene klotho regulates cellular
antioxidant capacity via binding to S-fromylglutathione
hydrolase through the N285 glycosylation site Y. Xu, L.
Dutcher and Z. Sun. Univ. of Oklahoma Hlth. Sci. Ctr.
A316 1095.4 Molecular mechanism of Rac1 regulation of
endothelial permeability N. Daneshjou, Y.A. Komarova, N.
Sieracki, M. Schwartz and A.B. Malik. Univ. of Illinois Col. of
Med., Chicago and Yale Univ. Sch. of Med.
A317 1095.5 Rac1 as a potential candidate for improved
insulin sensitivity following exercise S. Sheikh. California State
Univ., Los Angeles.
A318 1095.6 Long-term atorvastatin treatment inhibited prosurvival signaling, reduced mitochondrial function and altered
ultrastructural integrity in cardiac myocytes A.E. ZemljicHarpf, J.C. Godoy, J.M. Schilling, A. Kassan, A. Schwarz,
E.K. Asfaw, E.A. Alvarez, N.D. Dalton, I.R. Niesman and
H.H. Patel. UCSD and VA San Diego Healthcare Syst.
A319 1095.7 Bioinformatic analysis of differential protein
expression in calu-3 cells exposed to carbon nanotubes P. Li,
X. Lai, F. Witzmann and B. Blazer-Yost. Indian Univ.-Purdue
Univ. Indianapolis and Indiana Univ. Sch. of Med.
A320 1095.8 Endothelial cell surface expressed chemotaxis
and apoptosis regulator controls white adipose tissue lipolysis
through modulation of PI3/AKT pathway S. Kilari, I. Remadevi,
D. Sahoo, R. Ramchandran and G. Wilkinson. Med. Col. of
Wisconsin and Concordia Univ. of Wisconsin.
A321 1095.9 Proteomic profiling of quiescent and activated
airway epithelial NKCC1 C.M. Liedtke, P. Litman and G.
Gokulrangan. Case Western Reserve Univ.
A322 1095.10 Redox-sensitive activation of PI3K/Akt
pathway in RVLM on endoplasmic reticulum stress-associated
neurogenic hypertension Y-M. Chao and J.Y. Chan. Kaohsiung
Chang Gung Mem. Hosp. and Natl. Cheng Kung Univ., Taiwan.
A323 1095.11 Leukotriene D4 dephosphorylates ASCT1
through Ca2+ dependent PKCα-Akt pathway in intestinal
epithelial cells J. Talukder and J. Wright. LeMoyne-Owen
Col., TN.
367
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PHYSIOLOGYTUESDAY
A324 1095.12 TRPC channels are involved in endothelin 1
mediated inhibition of renin release from juxtaglomerular cells
M.C. Ortiz-Capisano. Henry Ford Hosp.
A325 1095.13 Src glutathionylation and its role in oxidant and
TGFβ1-mediated Src activation H. Zhang and H.J. Forman.
Univ. of Southern California and Univ. of California, Merced.
A326 1095.14 Inhibitory effects of J10 on lung cancer cell
motility: an in vitro and in vivo study C-H. Wu, S-C. Chen,
Y-C. Chien, C-H. Pan, C-Y. Chen and J-H. Sheu. Taipei Med.
Univ., China Med. Univ. and Natl. Sun Yat-sen Univ., Taiwan.
A327 1095.15 Decreased expression of activated placental
heat shock protein 27 in human and ovine intrauterine growth
restriction D. Merill, B. Bahr and J.A. Arroyo. Brigham Young
Univ.
A328 1095.16 cAMP/PKA-mediated regulation of amino acid
metabolism in murine T-lymphoma cells A. Wilderman, Y.
Guo, S. Taylor and P. Insel. UCSD.
A329 1095.17 Increases in protein expression of the
alpha7beta1 integrin pathway following 8 weeks of
acetaminophen administration in the rat soleus P. Gallagher,
Z. Graham, T. Broderick and C. Carroll. Univ. of Kansas and
Midwestern Univ., AZ.
A330 1095.18 The significance of IL-10 stimulation in cardiac
innate responses A.K. Bagchi, G. Akolkar, S. Mandal, X.
Gao, X. Yang and P.K. Singal. Univ. of Manitoba, Canada.
A331 1095.19 Targeting glucagon-like peptide-1 and α2
adrenergic receptor combination using GLP-1/yohimbine
to achieve β-cell specific targeting and therapy K.
Ananthakrishnan, C. Weber, N. Hart, J. Vagner, S. Limesand
and R. Lynch. Univ. of Arizona.
A332 1095.20 Mapping the dynamic Interactomes of
“druggable” membrane proteins: roles in human health and
disease I. Stagljar. Univ. of Toronto.
1096.CELLULAR RESPONSES TO INFLAMMATION
Poster
A333 1096.1 Protective effects of lower dose of melatonin
on TNFα-induced type II collagen loss in primary cultured
chondrocytes J-H. Kim, Y. Hong, J. Choi and Y. Hong. Col. of
Vet. Med., Gyeongsang Natl. Univ., Grad. Sch. of Inje Univ. and
Col. of Biomed. Sci. & Engin., Inje Univ., South Korea.
A334 1096.2 Effect of altered endogenous melatonin
concentration by conditional light control on cellular organization
in injured spinal cord Y. Jin, Y. Hong, K. Park and Y. Hong.
Grad. Sch. of Inje Univ. and Col. of Biomed. Sci. & Engin., Inje
Univ., South Korea.
A335 1096.3 Inhibition of IClswell impairs TNFα-dependent
activation of NF-κB N.A. Ettinger, H-N. Nguyen, C.D. Manlove
and F.S. Lamb. Vanderbilt Univ. Med. Ctr.
A336 1096.4 c-Jun N-terminal kinase inhibits TNFα-induced
NF-κB activation through endosomal Nox1 in vascular smooth
muscle cells H. Choi and F.S. Lamb. Vanderbilt Univ. Med. Ctr.
A337 1096.5 Lipopolysaccharide-induced inflammation is
associated with receptor for advanced glycation end products
in human endothelial cells L. Wang, T. Chen, J. Wu and Q.
Huang. Luzhou Med. Col. and Southern Med. Univ., China.
368
A338 1096.6 CORM-3 derived CO suppresses NLRP3
inflammasome in cardiac fibroblasts and protects
cardiomyocytes from apoptosis in mice with sepsis W. Zhang,
X. Xu, T. Mele, R. Kao, G. Cepinskas, C. Martin and T. Rui.
Affil. People’s Hosp. of Jiangsu Univ., China, Lawson Hlth.
Res. Inst., London, ON and Western Univ., Canada.
A339 1096.7 Role of cardiac fibroblasts in myocardial
dysfunction in mice with sepsis: effect of NLRP3 inflammasome
activation W. Zhang, X. Xu, R. Kao, T. Mele, C.M. Martin and
T. Rui. Lawson Hlth. Res. Inst., London, ON and Western
Univ., Canada.
A340 1096.8 Quercetin attenuates induction of COX-2
in rats subjected to acute unilateral ureteral obstruction I.G.
Carlsen and R. Nørregaard. Univ. of Aarhus, Denmark.
A341 1096.9 Modulation of the CX3CL1/CX3CR1 signaling
pathway by acetylsalicylic acid (aspirin) in human trophoblast
D. Szukiewicz, H. Alkhalayla and A. Stangret. Med. Univ. of
Warsaw.
A342 1096.10 Characterization of the immune response in
male and female mice following lipopolysaccharide-induced
systemic inflammation N. Bubalo, P. Nguyen, T.M. Nguyen,
T. Abramson and K.A. Wilkinson. San Jose State Univ.
1097.CELLULAR SIGNALING
Poster
A343 1097.1 Protease-activated receptor -3 signals
independent of protease-activated receptor-1 to regulate
endothelial nitric oxide synthase in human endothelial cells
L.C. Tillery and E. Motley-Johnson. Meharry Med. Col.
A344 1097.2 Effect of resveratrol on the erectile machinery is
due to the underlying mechanisms of the alpha 1-adrenoceptor
activation C.B. Restini, A.O. Domingos, B.F. Pereira and
D.F. Vieira. Univ. of Ribeirão Preto, Brazil.
A345 1097.3 The novel Mas agonist, CGEN 856S,
promotes Akt/eNOS activation and anti-proliferation with
FOXO1 involvement A.A.B. Peluso, D.G. Passos-Silva, G.M.
Etelvino, G. Rotman and R.A.S. Santos. Fed. Univ. of Minas
Gerais, Brazil and Compugen Ltd., Tel Aviv.
A346 1097.4 Dynamic measurements of [IP3]i in cardiac
differentiated P19 (CD-P19) cells with a novel quantum dots
(QD) and gold nanoparticles (AuNP) nanobiosensor, QD-IP3AuNP. H. Mao and L.B. Wong. Cytoptics Corp., San Diego.
A347 1097.5 Dynamic measurements of [K+]i in cardiac
differentiated P19 cells with a quantum dots (QD) potassium
nanobiosensor, K-QD L.B. Wong and H. Mao. Cytoptics
Corp., San Diego.
A348 1097.6 Dopamine D1-like receptors (D1R and
D5R) differently regulate phospho-PKC in HEK-293 cells
heterologously expressing human D1R or D5R P. Yu, J. Yang,
J. Yang, S. Yang and P. Jose. Univ. of Maryland Sch. of Med.
A349 1097.7 Dopamine D1-like receptors differently
regulate small G proteins in LRs in human embryonic kidney
cells heterologously expressing human D1 or D5 receptors P.
Yu, Y. Yang and P.A. Jose. Univ. of Maryland Sch. of Med.
A350 1097.8 NHE8’s role in male fertility involves LHR
protein trafficking H. Xu, H. Chen, J. Li and F. Ghishan. Univ.
of Arizona.
TUESDAYPHYSIOLOGY
A351 1097.9 Aldosterone activates colonic K secretion via
BK channels (KCa1.1) and membrane trafficking S. Halm and
D. Halm. Wright State Univ. Boonshoft Sch. of Med.
A352 1097.10 Ca2+ shuttling between endoplasmic reticulum
and mitochondria underlying ouabain-triggered Ca2+ oscillations
J.M. Fontana, M. Kruusmägi, H. Brismar and A. Aperia.
Karolinska Inst. and KTH, Royal Inst. of Technol., Stockholm.
A353 1097.11 Calcium signaling in the choroid plexus
epithelium T.A. Longden, A.D. Bonev and M.T. Nelson. Univ.
of Vermont.
A354 1097.12 Signal-transduction pathways in hemolysisassociated right-ventricular failure T. Olonisakin. Univ. of
Pittsburgh Sch. of Med.
A355 1097.13 The role of p38, ERK1/2 and JNK mitogen
activated protein kinase in the anti-hypertrophic action of AMPkinase in cardiomyocytes P.J. Lopez, G. Barreto, J. Soto and
S. Javadov. Univ. of Puerto Rico, Med. Sci. Campus.
A356 1097.14 MED28 regulates the development of
epithelial-mesenchymal transition and invasion in human lung
cancer cells N-T. Hsieh, C-I. Li, C-Y. Huang and M-F. Lee.
China Med. Univ. and Chang Jung Christian Univ., Taiwan.
A357 1097.15 Hsp90 acetylation regulates mineralocorticoid
receptor subcellular dynamics and aldosterone-induced
promoter transactivation D. Alvarez de la Rosa, R. JimenezCanino, F. Lorenzo-Diaz and T. Giraldez. Univ. of La Laguna
and Inst. of Biomed. Technol., Spain.
1098.INTRACELLULAR PH AND ACID-BASE
TRANSPORT
Poster
A358 1098.1 Fluctuations in surface pH of maturing rat
incisor enamel are a result of cycles of H+-secretion by
ameloblasts and variations in enamel buffer characteristics S.
Frische, H. Damkier, K. Josephsen, Y. Takano, D. Zahn and
O. Fejerskov. Aarhus Univ., Denmark, Grad. Sch. of Tokyo
Med. and Dent. Univ. and Friedrich Alexander Univ. ErlangenNürnberg.
A359 1098.2 Inhibition of Rhbg-mediated NH3 and NH4+
transport by DIDS T. Caner, S. Abdulnour-Nakhoul, K.
Brown, L.L. Hamm and N.L. Nakhoul. Tulane Univ.
A360 1098.3 Maintained intracellular acidification reduces
myogenic tone and vasomotion in mice cerebral arteries
C. Aalkjaer, A.B. Thomsen, S. Kim, F. Aalbaek and E.
Boedtkjer. Aarhus Univ., Denmark.
A361 1098.4 Decreased plasma CO2 induces redistribution
of the V-ATPase in the choroid plexus epithelium: involvement
in regulation of cerebrospinal fluid pH? H.L. Christensen,
H.H. Damkier, T.G. Paunescu, D. Brown and J. Praetorius.
Aarhus Univ., Denmark and Massachusetts Gen. Hosp. and
Harvard Med. Sch.
A362 1098.5 Regulation of ENaC, AE1 and H+ ATPase
in renal intercalated cell specific NBCe2 knockout mice F.D.
Pedersen, J. Praetorius and H.H. Damkier. Aarhus Univ.,
Denmark.
A363 1098.6 Apical NH4Cl acts to reduce intracellular Na
concentration in mTAL via cellular depolarization A. Guha, J.
Sun and P.M. O’Connor. Georgia Regents Univ.
A364 1098.7 Distinguishing HCO3- from CO3= transport by
the electrogenic Na/HCO3 cotransporter NBCe1 (SLC4A4) F.J.
Moss, S.K. Lee, M.D. Parker and W.F. Boron. Case Western
Reserve Univ.
A365 1098.8 Rescue of the disrupted enamel phenotype in
Slc4a4-null mice using explant organ culture maintained in a
living host kidney capsule X. Wen, I. Kurtz and M.L. Paine.
USC and UCLA.
1099.COMPARATIVE OSMOTIC, IONIC, AND ACIDBASE REGULATION
Poster
A366 1099.1 The European eel NCCβ encodes for an
electroneutral NaCl cotransporter that is not sensitive to
thiazide diuretics E. Moreno, C. Cutler, M. Chávez-Canales,
N. Vazquez and G. Gamba. INCMNSZ-IIB, UNAM, Mexico
City, Georgia Southern Univ. and Salvador Zubirán Natl. Inst.
for Hlth. Sci. and Nutr., UNAM, Mexico City.
A367 1099.2 Insights into kidney function during recovery
from anoxia in the painted turtle C.A. Hill and D.E. Warren.
Saint Louis Univ.
A368 1099.3 Interactions between activators of the larval
bullfrog epithelial cation channel D. Holbird. Bethany Lutheran
Col., MN.
A369 1099.4 Aquaglyceroporin HC-3 mediates hypotonicityinduced cell volume and shape changes in cultured erythrocytes
from Cope’s gray treefrog, Hyla chrysoscelis M. Hawk, P.
Nickell, J. Frisbie, D. Goldstein and C.M. Krane. Univ. of
Dayton and Wright State Univ.
A370 1099.5 Epinephrine regulates aquaglyceroporin HC-3
expression and subcellular localization in cultured erythrocytes
from the freeze-tolerant treefrog, Hyla chrysoscelis C.J.
Ratycz, P. Nickell, J. Frisbie, D.L. Goldstein and C.M.
Krane. Univ. of Dayton and Wright State Univ.
A371 1099.6 Ion regulation and stress tolerance during
oscillating salinity in two color morphs of the green crab,
Carcinus maenas A. Himes, W.S. Balschi and M. Frederich.
Univ. of New England.
A372 1099.7 Urea protects Caenorhabditis elegans against
hypertonic stress: a genetic model for cellular responses to
urea? E. Perez and K.P. Choe. Univ. of Florida.
1100.COMPARATIVE AND EVOLUTIONARY
PHYSIOLOGY
Poster
A373 1100.1 Molecular regulation of adiposity in a migrant,
the gray catbird K.R. Corder, D.E. Russell, J.M. Huss and
P.J. Schaeffer. Miami Univ. and City of Hope, Beckman Res.
Inst.
A374 1100.2 More is not always better: a hidden cost of the
flight-fecundity trade-off in the hawk moth, Manduca sexta B.
Wone, J. Ojha, H. Contreras and G. Davidowitz. Univ. of
Arizona, Univ. of Nevada-Reno and Univ. of La Verne, CA.
369
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PHYSIOLOGYTUESDAY
A375 1100.3 Feeding on the wing: energy allocation and
prioritization in the hawk moth Manduca sexta S. Arcas, G.
Davidowitz and H.L. Contreras. Univ. of La Verne and Univ.
of Arizona.
A376 1100.4 Aging increases resistance to bacterial
infection in the tobacco hornworm, Manduca sexta K. Booth,
L. Cambron, N. Fisher and K. Greenlee. North Dakota State
Univ. and Aurora Univ., IL.
A377 1100.5 The alkaline anterior midgut of larval
mosquitoes as a barrier for microorganisms H. Onken, M.
Bassous, D.F. Moffett and C. Corbo. Wagner Col., Staten
Island and Washington State Univ.
A378 1100.6 Serotonin and its influence on feeding behavior
of larval yellow fever mosquitoes H. Onken, P. Yuzon, E.
Citozi, E. Medina and D.F. Moffett. Wagner Col., Staten
Island and Washington State Univ. Sch. of Biol. Sci.
A379 1100.7 Serotonin modulates the heart rate through
5-HT2 receptor activation in Drosophila larvae A.L. Stacy, Z.
Majeed and R. Cooper. Univ. of Kentucky.
A380 1100.8 Calcium availability regulates calcium transport
by the chorioallantoic membrane of an oviparous squamate
A.J. Jackson, J.R. Stewart, R.A. Pyles and T.W. Ecay. East
Tennessee State Univ.
A381 1100.9 Eggshell calcium regulates embryonic growth
and calcium transport in an oviparous snake H.F. Frye, J.R.
Stewart, R.A. Pyles and T.W. Ecay. East Tennessee State
Univ.
A382 1100.10 Gravitational stress and the evolution of
relative tail-length in arboreal snakes C.M. Sheehy and H.B.
Lillywhite. Univ. of Florida.
A383 1100.11 Histamine
enhances
Syrian
hamster
hippocampal neuronal activity at low levels of synaptic
excitation K.J. Malins, J.S. Hamilton, J.M. Horowitz and
B.A. Horwitz. Univ. of California, Davis.
A384 1100.12 The effects of hypersalinity on the physiology
and morphology of a livebearing fish K. Castellanos, C.
Cavazos, K.F. Weaver, J. Garcia and P.F. Weaver. Univ. of La
Verne and Univ. of Colorado Boulder.
A385 1100.13 Thermoregulatory plasticity in Northern
Cardinals M. Komer, K. Corder and P. Schaeffer. Miami Univ.
A386 1100.14 The development of dive capacity in northern
elephant seal pups during the post-weaning fast D. Somo,
D. Ensminger, J. Sharick, S. Kanatous and D.E. Crocker.
Sonoma State Univ. and Colorado State Univ.
A387 1100.15 Range of hematology and biochemistry values
in open-water, captive bottlenose dolphins (Tursiops truncatus)
in Roatan, Honduras T.N. Maiden and C.B. Pogue. McLennan
Community Col., Waco.
A388 1100.16 Baseline hematology in Tursiops truncatus
(Atlantic bottlenose dolphins), Roatan, Honduras C.B. Pogue
and T.N. Maiden. McLennan Community Col., Waco.
1101.COMPARATIVE METABOLIC PHYSIOLOGY,
BIOCHEMISTRY, AND ENDOCRINOLOGY
Poster
A389 1101.1 Variations in pancreatic glucoregulatory
hormones in birds M. Calhoun, K. McGraw and K.L. Sweazea.
Arizona State Univ.
370
A390 1101.2 Post-exercise fate of lactate in the American
locust S.K. Tyler, M.W. Olson and S.D. Kirkton. Union Col.,
NY.
A391 1101.3 Impact of hypercapnic incubation on hatchling
common snapping turtle (Chelydra serpentina) growth and
metabolism O.H. Wearing, J. Eme, A. Kemp and D.A.
Crossley. Univ. of Manchester, McMaster Univ., Canada and
Univ. of North Texas.
A392 1101.4 The metabolic determinant underlying the rate
of energy use during prolonged fasting for the diamondback
watersnake, Nerodia rhombifer M. Larkin and S. Secor. Univ.
of Alabama.
A393 1101.5 Effects of an acute stimulation of the HPA axis
on sexual and stress hormones in male northern elephant seals
D.C. Ensminger, D.A. Somo, J.T. Sharick, D.S. Houser and
D.E. Crocker. Sonoma State Univ. and Natl. Marine Mammal
Fndn., San Diego.
A394 1101.6 Thyroid hormone changes associated with
prolonged food deprivation in adult male northern elephant
seals D. Lee, B. Martinez, D.E. Crocker and R.M. Ortiz. Univ.
of California, Merced and Sonoma State Univ.
A395 1101.7 Chronic effects of fibroblast growth factor 21
on whole body and liver metabolism in a natural animal model
of increased adiposity R.J. Samms, M. Murphy, P. Barrett,
T. Coskun, E. Paul, A.C. Adams, A. Kharitonenkov, K.
Tsintzas and E. Ebling. Univ. of Nottingham Med. Sch., Univ.
of Aberdeen, U.K. and Eli Lilly, Indianapolis.
A396 1101.8 Suppression of physical activity and nonresting energy expenditure during calorie restriction: role in
individual differences in adaptive thermogenesis S. Mukherjee,
E. Demuth, A. Spriggs, S.L. Britton, L.G. Koch and C.M.
Novak. Kent State Univ. and Univ. of Michigan.
A397 1101.9 Role of body composition and circulating
hormones on resting energy expenditure in obese pregnant
women M. Perez-Rodriguez, J. de Haene, D. Castañeda, N.
Stotland, E. Murphy, J. Talavera, P. Havel and J.C. King.
Mexican Soc. Security Inst., Univ. of California, Irvine, Univ.
of Birmingham, U.K., UCSF, Univ. of California, Davis and
Children´s Hosp. Oakland Res. Inst.
A398 1101.10 The (pro)renin receptor blocker peptide effects
on regulation of body weight and glucose homeostasis in
mice with diet-induced obesity Z. Shamansurova, P. Tan, S.
Bisotto, C. Michel, T.M-D. Nguyen, P.W. Schiller and J.L.
Lavoie. CR-CHUM, Univ. of Montreal, Univ. of Montreal Hosp.
Res. Ctr. and Clin. Res. Inst. of Montreal.
A399 1101.11 Regulation of avian PPAR activity by dietary
fatty acids A. Hamilton, J. Ly, K.R. Corder, P.J. Schaeffer
and J.M. Huss. City of Hope and Miami Univ.
A400 1101.12 Glucose infusion increases mRNA expression
of deiodinase 1 & 2, and thyroid hormone receptor β-1 in a
fasting-adapted mammal B. Martinez, J.G. Soñanez-Organis,
D.S. MacKenzie, D.E. Crocker and R.M. Ortiz. Univ. of
California, Merced, Sonora Univ., Mexico, Texas A&M Univ.
and Sonoma State Univ.
A401 1101.13 Metabolic signatures in overwintering raccoon
dogs (Nyctereutes procyonoides) L. Niiranen, K. Mäkelä, O.
Thalmann, S. Saarela and K-H. Herzig. Univ. of Oulu, Finland.
A402 1101.14 Post-mortal CO2 release by insects at high
temperatures E.C. Heinrich, E.M. Gray, A.S. Vorhees and
T.J. Bradley. Univ. of California, Irvine and Colorado Col.
TUESDAYPHYSIOLOGY
1102.SKELETAL MUSCLE PHYSIOLOGY
Poster
A403 1102.1 Instrument-assisted soft tissue manipulation
has no effect on the alpha7beta1 integrin pathway Z.A.
Graham, J.P. Vardiman, J.A. Siedlik, J.A. Deckert and P.M.
Gallagher. Univ. of Kansas.
A404 1102.2 Control of thin filament lengths by sarcomeric
tropomodulin isoforms: insights from mouse models D.S.
Gokhin and V.M. Fowler. The Scripps Res. Inst.
A405 1102.3 Effects of CaMKII activity on cardiac and
skeletal muscle pathology in a mouse model of Duchenne
muscular dystrophy N.M. Johnson, J.R. Levy, I.M. Grumbach,
M.E. Anderson and K.P. Campbell. Univ. of Iowa and HHMI,
Iowa City.
A406 1102.4 Motor unit recruitment patterns in genioglossus
and first dorsal interosseous K.R. Shumway, D. Porfirio and
F. Bailey. Univ. of Arizona.
A407 1102.5 Anti-inflammatory
effect
of
PEGylated
dexamethasone liposome for tourniquet-induced acute
ischemia-reperfusion injury in mouse skeletal muscle D.
Zhang, F. Yuan, H. Tu, J. Liu, D. Wang, R.L. Muelleman and
Y-L. Li. Univ. of Nebraska Med. Ctr.
A408 1102.6 Effects of muscle specific VEGF loss on muscle
hypertrophy and function induced by functional overload in
mice K.A. Huey, H. Delavar and E.C. Breen. Drake Univ. and
UCSD.
A409 1102.7 Collective effects of low cell pH and inorganic
phosphate on force, velocity, stiffness, and power in rat slow
and fast muscle fibers C.R. Nelson and R.H. Fitts. Marquette
Univ.
A410 1102.8 Muscle fibrosis due to loss of desmin increases
muscle stiffness due to an increased number of perimysial
collagen cables A.R. Gillies and R.L. Lieber. UCSD.
A411 1102.9 The effects of KATP channels on skeletal
muscle fatigue and recovery are dependent on muscle stimulus
frequency and fibre type M.E. Charter and C.L. Murrant. Univ.
of Guelph, Canada.
A412 1102.10 ICAM-1: a novel mechanism by which the
inflammatory response augments myogenesis Q. Goh, C.L.
Dearth, S.S. Awadia, R. Garcia-Mata, J.T. Corbett and F.X.
Pizza. Univ. of Toledo.
A413 1102.11 Myocardial
infarction
rapidly
induces
diaphragm muscle weakness T.S. Bowen, N. Mangner, S.
Werner, S. Glaser, A. Schrepper, T. Doenst, A. Linke, G.
Schuler and V. Adams. Leipzig Univ. Heart Ctr. and Univ. of
Jena, Germany.
A414 1102.12 Skeletal muscle fibers in dystrophin-deficient
mice express intercellular adhesion molecule-1 M.J. TorresPalsa, M.V. Koziol, Q. Goh, J. Peterson and F.X. Pizza. Univ.
of Toledo and The Ohio State Univ.
A415 1102.13 Neutrophil accumulation after contractioninduced muscle injury is dependent upon P- and E-selectin
D.D. Sloboda and S.V. Brooks. Univ. of Michigan.
A416 1102.14 Cellular aging of skeletal muscle: evidence that
physical inactivity is responsible and not age M. Venturelli, G.
Morgan, A. Donato, V. Reese, C. Tarperi, C. Milanese, F.
Schena, R. Bottura, C. Reggiani, F. Naro, R. Cawthon and
R. Richardson. Univ. of Utah, Univ. of Verona, Mazzali Fndn.,
Mantua, Italy, Univ. of Padua and Sapienza Univ.
A417 1102.15 Not all skeletal muscle fibers depend on the
myoprotection of KATP channels during fatigue J-M. Renaud
and D. Selvin. Univ. of Ottawa.
A418 1102.16 Altered contractile properties of fast and slow
skeletal muscles from db/db mice G. O’Connell, G. Guo and
E.E. Pistilli. West Virginia Univ.
A419 1102.17 The importance of decreased Cl- channel
activity in preventing K+-induced force depression at the onset
of muscle activity A. Higgins and J-M. Renaud. Univ. of
Ottawa.
A420 1102.18 Cigarette smoke impairs the in situ fatigue
resistance of locomotor skeletal muscle in mice B.M. Trisko,
L. Nogueira, P.D. Wagner and E.C. Breen. UCSD.
A421 1102.19 Effects of lipopolysaccharide-induced systemic
inflammation on the contractile properties of the fast twitch
extensor digitorum longus muscle in mice R.G. Mandawe and
K.A. Wilkinson. San Jose State Univ.
A422 1102.20 CD34 in skeletal muscle regeneration in
chronic obstructive pulmonary disease M. Pagé, A. Langlois,
A. Porlier, M-È. Thériault, A. Dubé, R. Debigaré and M-R.
Blanchet. Quebec Heart and Lung Inst. Res. Ctr.
A423 1102.21 SPRED1 in quadriceps of patients with mild
chronic obstructive pulmonary disease A. Porlier, A. Dubé, R.
Debigaré and F. Maltais. Univ. Laval and IUCPQ, Quebec.
A424 1102.22 Influence of myostatin on skeletal muscle
plasticity S. Reisz-Porszasz, A. Abraham, M.J. Baker and
V.J. Caiozzo. Charles R. Drew Univ. and Univ. of California,
Irvine.
A425 1102.23 Wnt3a potentiates myogenesis in C2C12
myoblasts through the modulation of intracellular calcium and
activation of the β-catenin signaling pathway J. Huang, C. Mo,
L. Bonewald and M. Brotto. Univ. of Missouri-Kansas City.
A426 1102.24 Mechanisms of skeletal muscle deformity
in hyperhomocysteinemia S. Veeranki, S. Givvimani, P.
Sathnur, N. Metreveli and S.C. Tyagi. Univ. of Louisville.
A427 1102.25 Role of synemin, an intermediate filament
protein, in adult skeletal muscle K. Garcia-Pelagio, J. Muriel,
L. Lund, M. Bond and R. Bloch. Univ. of Maryland Baltimore.
A428 1102.26 The effect of lipid concentration on myosin
heavy chain isoform expression in cultured Weddell seal
skeletal muscle cells T.M. Garcia and S. Kanatous. Colorado
State Univ.
A429 1102.27 Dysregulation of dysferlin during 7 days
mechanical unloading is mediated by ROS in rat soleus muscle
Y. Lee, M.S. Lawler, R.E. Botchlett, J.M. Hord and J.M.
Lawler. Texas A&M Univ. and Georgia Tech.
A430 1102.28 The effects of doxorubicin administration on
intramuscular nitric oxide concentration in rat skeletal muscle
J. Lalanne, S. Fabris and D. MacLean. Laurentian Univ.,
Canada and Northern Ontario Sch. of Med.
A431 1102.29 Physical inactivity promotes contractile
dysfunction at the whole tissue, cellular and molecular levels
in older adults D.M. Callahan, M.S. Miller, B.D. Beynnon, J.
Slauterbeck and M.J. Toth. Univ. of Vermont.
A432 1102.30 Exon 12 of slow skeletal troponin t affects
calcium sensitivity of force development and interactions
with other thin filament components J.R. Pinto, Q. Xu, M.S.
Parvatiyar, W.C. Oh, J.D. Potter and A.V. Gomes. Florida
State Univ., Univ. of California, Davis and Univ. of Miami Miller
Sch. of Med.
A433 1102.31 Temporal variation in skeletal muscle atrophic
pathways following transection of the sciatic nerve Z. Callahan,
C. Menke and P. Schaeffer. Miami Univ.
371
T
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PHYSIOLOGYTUESDAY
A434 1102.32 Phosphodiesterase inhibition increases PGC1α in muscle cells J.A. Rahnert, B. Zheng, M.E. WoodworthHobbs, M.B. Hudson and S.R. Price. Emory Univ. and Atlanta
VA Med. Ctr.
A435 1102.33 Effects of total knee arthroplasty on markers
of muscle damage two hours after surgery A.D. Hocker, B.A.
Jewett, S.N. Shah, B.A. Lantz and H.C. Dreyer. Univ. of
Oregon and Slocum Ctr. for Orthoped.
A436 1102.34 Angiotensin II type 2 receptor regulates skeletal
myoblast differentiation: implications for treatment of cachexia
and skeletal muscle wasting T. Yoshida and P. Delafontaine.
Tulane Univ. Sch. of Med.
A437 1102.35 Hypoxia regulated expression of erythropoietin
in cultured myoblasts and myotubes J. Baker and G. Parise.
McMaster Univ., Canada.
A438 1102.36 Bone marrow inoculation of Walker 256 tumor
cells in rats as a model of cancer cachexia C.R. Alves, N.R. de
Almeida, W. das Neves, V.P. Gutierrez, V. Voltarelli, Y. Cury,
B. Gualano, M. Seelaender, A.H. Lancha Junior and P.C.
Brum. Univ. of São Paulo.
A439 1102.37 Radiation induced inhibition of myogenesis
following muscle damage from cardiotoxin injection J.A.
Cotter, M. Baker, M. Acharya, C. Limoli and V. Caiozzo.
Univ. of California, Irvine.
A440 1102.38 Effect of 17β estradiol on statin-induced
apoptosis M.L. Bielman, K. Barlas, C. Hoffman and K. Ball.
Alma Col., MI.
A441 1102.39 AT1 receptor blocker attenuates mechanical
ventilation-induced atrophy and oxidative stress in the
diaphragm muscle O-S. Kwon, A.J. Smuder, K.J. Sollanek,
M.P. Wiggs, E.E. Talbert and P.K. Scott. Univ. of Florida.
A442 1102.40 Phosphorylation of nNOSα promotes muscle
cell differentiation R. Kar, B.S. Masters and L. Roman. Univ.
of Texas Hlth. Sci. Ctr. at San Antonio.
A443 1102.41 LAT1 muscle-specific knockout limits early
load-induced mTORC1 activity N.W. Aguirre and K. Baar.
Univ. of California, Davis.
A444 1102.42 Role of small heat shock proteins in muscle
under chronic hyperglycemia V.S. Reddy and G.B. Reddy.
Natl. Inst. of Nutr., Hyderabad, India.
A445 1102.43 Heat shock proteins protect skeletal muscle
against frostbite injury R. Mestril, J. Batey, T. Liskutin and C.
Schweigert. Loyola Univ. Chicago, Maywood.
A446 1102.44 Short- and long-term effects of ActRIIB receptor
ligand trapping agents on muscle mass and downstream
signaling in dystrophic (mdx) limb and respiratory musculature
R. Potter, P. Desai, C. Nielsen, K. Corbell, C. Mellon, A.
Danishyar, F. Gatti, A. Grinberg, R. Kumar, C. Carroll and
C.G. Carlson. Midwestern Univ., AZ, Kirksville Col. Osteo.
Med. and Acceleron Pharma, Cambridge, MA.
A447 1102.45 Myostatin expression and high fat diet effects
on skeletal muscle and adipose metabolism in mouse S.
Constantinescu, A. Abraham and S. Reisz-Porszasz.
Charles R. Drew Univ.
A448 1102.46 Roles of FOXO signaling and mitochondrial
dynamics in muscle disuse atrophy D. Yeo, C. Kang, C. Song,
T. Zhang and L.L. Ji. Univ. of Minnesota, Minneapolis and
Tianjin Univ. of Sport, China.
372
1103.REDUCED GRAVITY AND HYPERBARIC
ENVIRONMENTS
Poster
A449 1103.1 Physiological heart rate profile of hyperbaric
underwater worker during an exercise stress testing as a
predictor of physical fitness A. Duvallet, E. Duvallet, F.
Lhuissier, P. Constantin and M. Beaudry. AP-HP, Hosp.
Avicenne, Sorbonne-Paris-Cité, Univ. Paris 13, Inst. Gustave
Roussy, Villejuif, Sorbonne-Paris-Cité, Univ. Paris 13 and HIA
Val de Grâce, Paris.
A450 1103.2 Physiological systemic pressure profile of
hyperbaric underwater worker during exercise stress testing
as a predictor of physical fitness A. Duvallet, E. Duvallet,
F. Lhuissier, P. Constantin and M. Beaudry. AP-HP, Hosp.
Avicenne, Sorbonne-Paris-Cité, Univ. Paris 13, Inst. Gustave
Roussy, Villejuif, Sorbonne-Paris-Cité, Univ. Paris 13 and HIA
Val de Grâce, Paris.
A451 1103.3 Lower body negative pressure counters
headward fluid shifts in the brain and eye B.R. Macias, N.
Grande Gutierrez, A.R. Hargens and J.H. Liu. UCSD.
A452 1103.4 Body position does not affect respiratory sinus
arrhythmia magnitude M. Abrosimova, J. Baden and T.A.
Day. Mount Royal Univ., Canada.
A453 1103.5 Leucine supplementation partially preserves
neuromuscular activation during bed rest J.A. Mettler, B.M.
Doucet, K.L. English, S.M. Bennett and D. Paddon-Jones.
Texas State Univ. and Univ. of Texas Med. Branch.
A454 1103.6 Hyperbaric oxygen therapy alters vascular
reactivity independent of ATP B. Hake, B. Eovaldi and F.
Sylvester. Grand Valley State Univ. and U.S. Air Force,
Vandenberg AFB, CA.
A455 1103.7 Radiation combined with hind-limb suspension
affects physiological parameters in rats P. Chowdhury,
A. Long, N. Akel, D. Gaddy, R. Griffin, L. Bailey and M.
Dobretsov. Univ. of Arkansas for Med. Sci.
1104.TEMPERATURE REGULATION
Poster
A456 1104.1 Effects of physical training on thermoregulation
during exercise in spontaneously hypertensive rats H.P.
Santiago, L.H.R. Leite, P.M.D.A. Lima, T.N. Prímola-Gomes,
A.C.L. Rodrigues and C.C. Coimbra. Fed. Univ. of Minas
Gerais, Fed. Univ. of Juiz de Fora, Fed. Univ. of Viçosa and
Fed. Univ. of Jequitinhonha and Mucuri Valleys, Brazil.
A457 1104.2 Large differences in body fat do not
independently alter changes in core temperature during
exercise S. Dervis, J. Smoljanic and O. Jay. Univ. of Ottawa
and Univ. of Sydney.
A458 1104.3 The independent Influence of aerobic fitness
and running economy on thermoregulation during running J.
Smoljanic, S. Dervis, N.B. Morris and O. Jay. Univ. of Ottawa
and Univ. of Sydney.
TUESDAYPHYSIOLOGY
A459 1104.4 Skin temperature responses following a
warm-weather road race L.N. Belval, B.A. Comstock, R.A.
Huggins, R.L. Stearns, Y. Hosokawa, A.L. McKenzie, J.E.
Earp and D.J. Casa. Univ. of Connecticut and Westfield State
Univ., MA.
A460 1104.5 Electric fans mitigate cardiovascular and
thermal strain during extreme heat events N. Ravanelli and O.
Jay. Univ. of Ottawa.
A461 1104.6 The effect of the head or neck cooling on
body core temperature and thermal sensation in humans M.
Matsuda-Nakamura, S. Wada, S. Marui, N. Sato and K.
Nagashima. Waseda Univ., Japan.
A462 1104.7 Hydrogen sulfide elicits vasodilation in the
human cutaneous circulation in a dose-dependent manner J.L.
Kutz, W.L. Kenney and L.M. Alexander. Penn State.
A463 1104.8 Aerobic
fitness
affects
noradrenergic
involvement in cutaneous vasoconstriction to local and whole
body cooling J.T. Miller and G.J. Hodges. Univ. of Alabama.
A464 1104.9 Steady-state local sweat rate is determined
by the evaporation required for heat balance relative to body
surface area M.N. Cramer and O. Jay. Univ. of Ottawa Sch. of
Human Kinet.
A465 1104.10 Regional differences in the cutaneous thermal
sensitivity to wetness across the torso D. Filingeri, B.
Redortier, S. Hodder and G. Havenith. Loughborough Univ.,
U.K. and Oxylane Res., Villeneuve d’Ascq, France.
A466 1104.11 Time course of heat acclimation in burn
survivors with well-healed grafted skin E. Rivas, Z.J. Schlader,
M.S. Ganio, J. Pearson, R.A.I. Lucas, D. Gagnon and C.G.
Crandall. Texas Woman’s Univ., Inst. for Exercise and Envrn.
Med., Dallas, Univ. of Arkansas, Cardiff Metropolitan Univ. and
Umea Univ., Sweden.
A467 1104.12 Aspirin ingestion does not alter the onset
or slope of local sweat rate during whole-body passive heat
stress S.J. Carter, R.L. Herron, S.Z. Akers, A.B. Collins and
J.E. Wingo. Univ. of Alabama.
A468 1104.13 Indomethacin increases organ damage and
heat stroke mortality in mice L.R. Leon, S.M. Dineen and M.L.
Plamper. U.S. Army Res. Inst. of Envrn. Med., Natick, MA.
A469 1104.14 Liver necrosis during severe heat stroke
recovery is associated with activation of the complement
system R.M. Duran, C.M. Quinn and L.R. Leon. U.S. Army
Re.s Inst. of Envrn., Med., Natick, MA.
A470 1104.15 Heat stroke decreases cytokine and chemokine
gene expression in the hypothalamus of rats G.N. Audet, J.A.
Ramon, S.M. Dineen and L.R. Leon. U.S. Army Res. Inst. of
Envrn. Med., Natick, MA.
A471 1104.16 Central angiotensin AT2-receptor blockade
affects thermoregulation and running performance in rats A.S.
Pimentel, E.C. Rezende, T.N.P. Gomes, C.C. Coimbra and
L.H.R. Leite. Fed. Univ. of Juiz de Fora, Fed. Univ. of Viçosa
and Fed. Univ. of Minas Gerais, Brazil.
A472 1104.17 Thermoregulatory dysfunction in multiple
sclerosis patients during moderate exercise in a thermoneutral
environment M. Huang, N.B. Morris, O. Jay and S.L. Davis.
Southern Methodist Univ., Univ. of Ottawa and Univ. of Sydney.
A473 1104.18 Acute heat stress responses of mice with sickle
cell trait Y. Chen and A. Islam. Uniformed Svcs. Univ. of Hlth.
Sci.
A474 1104.19 Thermoregulatory responses to heat stress
and hypoxia D.A. Low, T.G. Bailey and H. Jones. Liverpool
John Moores Univ.
A475 1104.20 Hemodynamic responses to severe heat
stress in rats: implications for blood pressure regulation N.
Charkoudian, C. Quinn, R. Duran and L. Leon. U.S. Army
Res. Inst. of Exptl. Med., Natick, MA.
A476 1104.21 Muscle oxygen saturation during hyperthermic
central hypovolemia Z.J. Schlader, E. Rivas, N. Kennedy,
J.D. Kern, B.R. Soller, V.A. Convertino and C.G. Crandall.
Inst. for Exercise and Envrn. Med., Dallas, Texas Woman’s
Univ.,Reflectance Med. Inc., Westborough, MA, Univ. of
Massachusetts Med. Sch. and U.S. Army Inst. of Surg. Res.,
Fort Sam Houston.
A477 1104.22 Active and passive heat stress similarly
compromises tolerance to a simulated hemorrhagic challenge
J. Pearson, R.A. Lucas, Z.J. Schlader, J. Zhao, D. Gagnon
and C.G. Crandall. Cardiff Metro. Univ., U.K., Univ. of Texas
Southwestern Med. Ctr., Uema Univ., Sweden and China Inst.
of Sports Sci., Beijing.
A478 1104.23 Determinants of core temperature thresholds
for exercise ventilation M.D. White, A. Yogev, A.E. Beaudin,
D.J. Martin and M.L. Walsh. Simon Fraser Univ., Canada.
A479 1104.24 Temperature affects maximum H-reflex
amplitude but not homosynaptic postactivation depression S.
Racinais and A.G. Cresswell. Qatar Orthopaed. and Sports
Med. Hosp., Doha and Univ. of Queensland, Australia.
A480 1104.25 Polar bear body temperatures and behavior
in the changing Arctic summer J. Whiteman, H. Harlow, M.
Ben-David and G. Durner. Univ. of Wyoming and USGS
Anchorage.
A481 1104.26 Effects of environmental temperature and
humidity on a model of exertional heat stroke in mice M.A.
King, L. Leon and T. Clanton. Univ. of Florida and U.S. Army
Res. Inst. of Envrn. Med., Natick, MA.
A482 1104.27 Exercise-induced hyperthermia exacerbates
the rightward displacement in the force-frequency relationship
compared with passive hyperthermia J. Periard, S. Racinais
and M. Thompson. Qatar Orthopaed. and Sports Med. Hosp.,
Doha and Univ. of Sydney, Lidcombe.
A483 1104.28 An excitatory projection from median preoptic
area to the dorsomedial hypothalamus contributes to the
activation BAT thermogenesis D. Tupone and S.F. Morrison.
A484 1104.29 Optimal hypothermia to protect arrested heart
in vivo X-H. Ning, O.M. Villet, M. Ge, L.N. Sckhar, T.S. Tylee,
M.A. Corson, L. Yao, C. Zhu, L-P. Fan, Y-K. Soh, E. Wang,
A.K. Olson, D.L. Anderson, N.E. Buroker, C-S. Xu, S-H.
Chen and M.A. Portman. Children’s Hosp. and Reg. Med.
Ctr., Univ. of Washington, Harborview Med. Ctr. and Seattle
Keiro Rehab. & Care Ctr.
A485 1104.30 Differential effects of clonidine and lisinopril on
thermoregulatory and cardiovascular function during chronic
exposure to exertional heat stress in rats H.M. Stauss, N.
Choudhary, A.M. Moss and K.C. Kregel. Univ. of Iowa.
1105.THERMAL PHYSIOLOGY OF LABORATORY
MICE: DEFINING THE THERMONEUTRAL ZONE
Poster
A486 1105.1 Effects of housing temperature on stressinduced hyperthermia in mice, and the associated change
in voluntary motor activity P. Boily and D. Ring. Western
Connecticut State Univ.
373
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PHYSIOLOGYTUESDAY
A487 1105.2 Physiological impact of caloric restriction on
the lower critical temperature and body temperature dynamics
in mice S. Swoap, P. Joslin, C. Jaramillo and S. Shote.
Williams Col.
A488 1105.3 Gender difference in thermal perception
and the role of estrogen in mice K. Nagasihma, S. Marui,
M. Tsunakawa, C. Obata, H. Matsushita, N. Waki and H.
Harada. Waseda Univ., Japan.
A489 1105.4 Loss of SLN-mediated thermogenesis is
compensated by increased brown adipose tissue activity L.
Rowland, N. Bal and M. Periasamy. The Ohio State Univ.
A490 1105.5 Thermal effect induced by anandamide is
dissociated of locomotor and feeding behavior P.M.A. Lima,
F.S.M. Machado and C.C. Coimbra. Fed. Univ. of Minas
Gerais, Brazil.
1106.VASCULAR RESPONSE TO EXERCISE AND
ENVIRONMENTAL STRESS
Poster
A491 1106.1 Effect of passive heating on arterial compliance
in smokers vs. non-smokers N.E. Moyen, M.S. Ganio, J.M.
Burchfield, M.A. Tucker, M.A. Gonzalez, E.K. Dougherty,
F.B. Robinson, C.B. Ridings and J.C. Veilleux. Univ. of
Arkansas.
A492 1106.2 Tempol improves cutaneous thermal hyperemia
through increasing nitric oxide bioavailability in young smokers
N. Fujii, V.E. Brunt, M.A. Francisco and C.T. Minson. Univ.
of Oregon.
A493 1106.3 Sex differences observed in forearm exercise
vasodilation are not mediated through differences in nitric oxide
or prostaglandin signaling J.M. Kellawan, R.E. Johansson,
J.W. Harrell, J. Trierweiler, M.K. Crain, J.J. Sebranek, B.J.
Walker, M.W. Eldridge and W.G. Schrage. Univ. of WisconsinMadison.
A494 1106.4 Prostaglandins contribute in an O2-dependent
manner to exercise hyperaemia following rhythmic and
isometric handgrip exercise in young and older healthy
subjects R.T. Junejo, C.J. Ray and J.M. Marshall. Univ. of
Birmingham, U.K.
A495 1106.5 Experimental investigation of non-freezing
cold-induced injury: are young Asian males more susceptible
than young white Caucasians and are cyclooxygenase
products involved? W. Blevins, M. Tipton and J.M. Marshall.
Univ. of Birmingham and Univ. of Portsmouth.
A496 1106.6 Neurovascular responses to whole-body cold
stress in aged humans J.L. Greaney, W.L. Kenney and L.M.
Alexander. Penn State.
A497 1106.7 Pre-exercise whole-body cooling decreases
blood volume and oxygenated hemoglobin content in skeletal
muscle during submaximal exercise D. Gagnon, H. Kyröläinen,
S. Gagnon, K-H. Herzig, H. Rintamäki and J. Peltonen. Univ.
of Jyväskylä, Finland, Univ. of Western Ontario, Univ. of Oulu,
Finnish Inst. of Occup. Hlth., Oulu and Univ. of Helsinki.
A498 1106.8 Total sleep deprivation and pain perception
during cold noxious stimuli in humans: role of sex R.A. Larson,
H. Yang, J.J. Durocher and J.R. Carter. Michigan Technol.
Univ. and Beth Israel Deaconess Med. Ctr., Harvard Med. Sch.
374
A499 1106.9 Aerobic exercise increases stress resistance
in arteries of old mice R.A. Gioscia-Ryan, M.L. Battson, A.L.
Sindler, L.M. Cuevas, M.C. Zigler and D.R. Seals. Univ. of
Colorado Boulder.
A500 1106.10 Aging is associated with slowed vasodilator
kinetics in dynamically contracting muscle: role of nitric oxide
D.P. Casey, B.G. Walker, S.M. Ranadive and M.J. Joyner.
Univ. of Iowa and Mayo Clin.
A501 1106.11 Local 5-methyltetrahydrofolate administration
augments NO-dependent vasodilation in aged human skin
A.E. Stanhewicz, L.M. Alexander and W.L. Kenney. Penn
State.
A502 1106.12 Regional difference in blood flow response
to hypercapnia A. Miyaji, T. Ikemura, Y. Hamada and N.
Hayashi. Kyushu Univ. and Tokyo Inst. of Technol.
A503 1106.13 Effect of hyperoxia on contraction-induced
forearm blood flow dynamics in young healthy adults S.M.
Ranadive, M.J. Joyner, B.G. Walker, J.L. Taylor and D.P.
Casey. Mayo Clin. and Univ. of Iowa.
A504 1106.14 Involvement of NAD(P)H oxidase in acroleininduced oxidative stress Z. Yousefipour and M.A. Newaz.
Texas Southern Univ. and Chicago State Univ.
A505 1106.15 Role of rat vascular KATP channels in setting
microvascular oxygen pressure at the onset of contractions
C.T. Holdsworth, S.K. Ferguson, J.L. Wright, A.J. Fees,
D.C. Poole and T.I. Musch. Kansas State Univ.
A506 1106.16 Impact of nitrate supplementation via beetroot
juice on capillary hemodynamics in skeletal muscle of rats in
chronic heart failure S.K. Ferguson, C.T. Holdsworth, J.L.
Wright, A.J. Fees, T.I. Musch and D.C. Poole. Kansas State
Univ.
A507 1106.17 Influence of TNF-α on vasodilation of isolated
rat pulmonary artery rings A.K. Gassama, C.J. Ray, A.M.
Turner, S. Egginton and P. Kumar. Univ. of Birmingham and
Univ. of Leeds.
A508 1106.18 Effects of hindlimb unloading and radiation on
vasodilator responses in skeletal muscle arteries P. Ghosh,
J.N. Stabley, C. Kilar, B.J. Behnke, J. Alwood, Y. Shirazi, R.
Globus and M.D. Delp. Univ. of Florida and NASA Ames Res.
Ctr.
A509 1106.19 Is sustained post-exercise vasodilation
associated with an exercise-induced mast cell activation? S.A.
Romero, M.R. Ely, D.C. Sieck, T.M. Buck, D.A. MacLean and
J.R. Halliwill. Univ. of Oregon and Northern Ontario Sch. of
Med.
A510 1106.20 Adenosine receptor activation influences
postexercise skin blood flow R.N. McGinn, N. Fujii and G.P.
Kenny. Univ. of Ottawa.
A511 1106.21 The endothelial responses to low- and highintensity cycling with diesel exhaust exposure L.V. Giles, N.
Richard, J. Ruan, S. Tebbutt, C. Carlsten and M.S. Koehle.
Univ. of British Columbia.
A512 1106.22 Aerobic training prevents the impaired vascular
reactivity of fructose-treated rats R.F. Medeiros, T.G. Gaique,
T.B. Bernardes, N.A.V. Motta, F.C.F. Brito, J.M. Bertoldi,
C.F. Santos, K.J. Oliveira and A.C.L. Nóbrega. Fluminense
Fed. Univ., Brazil.
A513 1106.23 Transcriptome-wide RNA sequencing analysis
of rat skeletal muscle feed arteries: impact of exercise training
in obesity J. Padilla, N.T. Jenkins, P.K. Thorne, J.S. Martin,
R.S. Rector, J.W. Davis and M.H. Laughlin. Univ. of MissouriColumbia, Univ. of Georgia and Quinnipiac Univ., CT.
TUESDAYPHYSIOLOGY
1107.OBESITY AND SATIETY
1108.PANCREATIC HORMONES AND DIABETES
Poster
Poster
A514 1107.1 Acute intermittent hypoxia alters leptin
signaling pathways in arcuate nucleus J.M. Moreau, A.M.
McCoy, D.L. Jones and J. Ciriello. Univ. of Western Ontario
and SAGE Labs., St. Louis.
A515 1107.2 Efficacy of a novel green coffee bean extract
(GCB-70) in weight management A. Swaroop, M. Bagchi, P.
Kumar and D. Bagchi. Cepham Inc., Piscataway and Univ. of
Houston Col. of Pharm.
A516 1107.3 Chronic carbon monoxide inhalation has a
transient effect to reduce weight gain in mice fed a high fat diet
P.A. Hosick, E.K. Ahmed, M.U. Gousset, J.P. Granger and
D.E. Stec. Univ. of Mississippi Med. Ctr.
A517 1107.4 The gut microbiota suppresses insulinmediated fat accumulation via GPR43 I. Kimura, K. Ozawa,
D. Inoue, K. Ayukawa and G. Tsujimoto. Grad. Sch. of
Pharmaceut. Sci., Kyoto Univ., Tokyo Univ. of Agr. and Technol.
and Nara Med. Univ.
A518 1107.5 Dopamine D2 receptors regulate leptin and
IL-6 in 3T3 L1 adipocytes S. Cuevas, Y. Yang, K. Upadhyay,
I. Armando and P.A. Jose. Univ. of Maryland Sch. of Med. and
Stony Brook Long Island Children’s Hosp., Stony Brook Univ.
A519 1107.6 Effect of meal composition on postprandial
blood glucose levels in middle aged and young adults C.E.
Koch, J.L. Koch and M.K. Hopper. Univ. of Southern Indiana.
A520 1107.7 Influence of abdominal obesity on circulating
oxidative and inflammatory markers in overweight/obese
adult men C.A. Beckstrom, T.D. Bammert, C.A. Dow, G.M.
Lincenberg, K.J. Diehl, J.J. Greiner, B.L. Stauffer and C.A.
DeSouza. Univ. of Colorado Boulder.
A521 1107.8 Cholecystokinin activates a Ca2+-dependent
Cl- conductance in intestinal nodose neurons that is inhibited
in diet-induced obesity and may suppress satiety R. Wang, Y.
Lu, M.Z. Cicha, K. Rahmouni, M.W. Chapleau, C.J. Benson
and F.M. Abboud. Univ. of Iowa.
A522 1107.9 Intrauteruterine growth restriction increases
tyrosine hydroxylase expression and propensity for addiction
in low birth weight rats K. Ondek and E. Keen-Rhinehart.
Susquehanna Univ.
A523 1107.10 NanoSOD
reduces
adipose
tissue
inflammation in obesity V. Saraswathi, G. Murali, C.V.
Desouza, D.S. Manickam, T.K. Bronich and A.V. Kabanov.
Univ. of Nebraska Med. Ctr., VA Nebraska Western Iowa Hlth.
Care Syst. and Univ. of North Carolina at Chapel Hill.
A524 1107.11 HF-feeding-induced endoplasmic reticulum
stress links metabolic syndrome Y. Sakar, B. Langelier, F.
Devime and M. Covasa. INRA, Jouy en Josas and Western
Univ. of Hlth. Sci., CA.
A525 1107.12 Impaired enteroendocrine cells differentiation
signaling pathways through microbiota transfer Y. Sakar, B.
Langelier, F. Devime and M. Covasa. INRA, Jouy en Josas
and Western Univ. of Hlth. Sci., CA.
A526 1108.1 Multivalent cell specific therapeutics for
treatment of metabolic disorders R. Lynch, C. Weber, N. Hart,
S. Limesand, L. Xu, D. Morse, R. Gillies and J. Vagner. Univ.
of Arizona and Moffit Cancer Ctr., Tampa.
A527 1108.2 GLP-1 linked to an α2-adrenergic antagonist
enhances glucose disposal L. Stein, G.L. Yosten, K.
Ananthakrishnan, J. Wagner, R.M. Lynch and W.K.
Samson. Saint Louis Univ. and Univ. of Arizona.
A528 1108.3 Probing the intra-islet control of beta cell
function M. Elrick, G. Yosten, A. Salvatori and W. Samson.
Saint Louis Univ.
A529 1108.4 C-peptide and insulin at physiological ratios
rescue low O2-induced ATP release from erythrocytes (RBCs)
of humans with type 2 diabetes: implications for the prevention
of microvascular complications J.P. Richards, G.L. Yosten,
G.R. Kolar, E.A. Bowles, A.H. Stephenson, M.L. Ellsworth
and R.S. Sprague. Saint Louis Univ.
A530 1108.5 Expression of the receptor for proinsulin
C-peptide, GPR146, in the kidney L. Redlinger, G.R. Kolar,
W.K. Samson and G.L. Yosten. Saint Louis Univ.
A531 1108.6 Expression and function of bile acid receptor
TGR5 in glucagon secreting pancreatic α cells: hyperglycemia
induced expression of PC1 and release of GLP-1 in response
to activation of TGR5 by bile acids D.P. Kumar, S. Mahavadi,
F. Mirshahi, J.R. Grider, K.S. Murthy and A.J. Sanyal.
A532 1108.7 Effect of vitamin D on insulin resistance and
tissue inflammation in western and control diet-fed mice S.J.
Mutt, G.S. Raza, T. Karhu, S. Keinänen-Kiukaanniemi, M-R.
Jarvelin and K-H. Herzig. Univ. of Oulu, Finland and Imperial
Col. London.
A533 1108.8 Is extreme physiology of Burmese pythons
relevant to diabetes? S. Secor, A. Choudhary, M. Lundh and
B. Wagner. Univ. of Alabama, Broad Inst. of Harvard and MIT
and Harvard Univ.
A534 1108.9 Glucolipotoxicity-induced p21 suppresses prosurvival signaling in pancreatic β cells A.M. Hernandez, E.S.
Colvin and P.T. Fueger. Indiana Univ. Sch. of Med.
A535 1108.10 Forkhead box transcription factors are required
for expression of the glycemia-protective enzyme angiotensinconverting enzyme 2 in pancreatic β-cells K.B. Pedersen and
E. Lazartigues. LSU Hlth. Sci. Ctr., New Orleans.
A536 1108.11 Mitogen-inducible gene 6 haploinsufficiency
protects mice against streptozotocin-induced diabetes Y-C.
Chen, E.S. Colvin and P.T. Fueger. Indiana Univ. Sch. of Med.
A537 1108.12 Chronic blockade of the renin-angiotensin
system improves glucose metabolism and pancreatic
superoxide dismutase activity in insulin resistant rats R.
Rodriguez, J.N. Minas, J.P. Vazquez-Medina, D. Nakano, A.
Nishiyama and R.M. Ortiz. Univ. of California, Merced and
Kagawa Univ. Med. Sch.
A538 1108.13 Compound 21 ameliorates type 2 diabetes in
Zucker diabetic fatty rats by islet preservation C. Shao, L. Yu
and L. Gao. Univ. of Nebraska Med. Ctr.
A539 1108.14 Shedding of ACE2 by mature form of ADAM17
is mediated by angiotensin type 1 receptor H. Chodavarapu,
K. Chhabra, K.B. Pedersen and E. Lazartigues. LSU Hlth.
Sci. Ctr., New Orleans.
375
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PHYSIOLOGYTUESDAY
1109.REGULATION OF EPITHELIAL
TRANSPORTERS, PARACELLULAR
TRANSPORT, AND REGULATORY PROTEINS
Poster
A540 1109.1 Proteomic profiling of ubiquitinated proteins in
human urinary exosomes A.R. Huebner, L. Cheng, R. Fenton
and T. Pisitkun. Aarhus Univ., Denmark and Chulalongkorn
Univ., Thailand.
A541 1109.2 Fructose stimulates phosphorylation and
trafficking of the Na/K/2Cl cotransporter in rat thick ascending
limbs G.R. Ares, K. Kassem and P.A. Ortiz. Henry Ford Hlth.
Syst.
A542 1109.3 Estrogen, progesterone and prolactin are
involved in the sex-dimorphic regulation of the renal NaCl
cotransporter L. Rojas-Vega, L. Reyes-Castro, P. Meade, P.
De los Heros, R. Bautista, J. Hadchouel, E. Zambrano and
G. Gamba. Salvador Zubirán Natl. Inst. of Med. Sci. and Nutr.,
Mexico City, Ignacio Chávez Natl. Inst. of Cardiol., Mexico City
and INSERM UMR970, Paris.
A543 1109.4 A role for the circadian clock protein Per1 in
the regulation of NHE3 and SGLT1 in human proximal tubule
cells J. Richards, S. All, K-Y. Cheng and M. Gumz. Univ. of
Florida.
A544 1109.5 Regulation of NCC and the WNK cascade by
the circadian clock protein Per1 in murine distal convoluted
tubule cells J. Richards, B. Ko, S. All, K-Y. Cheng, R. Hoover
and M. Gumz. Univ. of Florida, Univ. of Chicago and Emory
Univ.
A545 1109.6 The kinase WNK1 is a powerful inhibitor of the
K+:Cl- cotransporters Z. Melo, A. Murillo, M. Chávez-Canales,
N. Vázquez, J. Hadchouel, G. Gamba and A. Mercado.
Salvador Zubirán Natl. Inst. for Hlth. Sci. and Nutr., UNAM,
Mexico City, INSERM, Paris and INCAR, Mexico City.
A546 1109.7 SPAK/OSR1 kinases directly phosphorylate
the K+-Cl- co-transporters P. de los Heros, J. Zhang, R.
Gourlay, D.G. Campbell, M. Deak, T.J. Macartney, K.T.
Kahle and D.R. Alessi. Dundee Univ., Nestle Inst. of Hlth. Sci.,
Lausanne, Children´s Hosp. Boston and Massachusetts Gen.
Hosp., Harvard Med. Sch.
A547 1109.8 Activation of the AT1 receptor-beta-arrestin
signaling pathway inhibits NHE3 activity in the renal proximal
tubule C.P. Carneiro de Morais, M. Oliveira-Souza, T.D.
Pessoa, G. Malnic, J.E. Krieger and A.C. Girardi. Univ. of
São Paulo.
A548 1109.9 Biphasic effect of PGF2a on the basolateral 40
pS K channel (a heterotetramer of Kir4.1 and Kir5.1) in the
early distal convoluted tubule (DCT1) L. Wang, C. Zhang, X.
Su and W-H. Wang. New York Med. Col.
A549 1109.10 Quantitative
phosphoproteomics
studies
reveal different signaling cascades in cultured distal convoluted
tubular cells upon vasopressin or angiotensin II stimulation L.
Cheng, T. Pistikun and R. Fenton. Aarhus Univ., Denmark
and Fac. of Med., Bangkok.
A550 1109.11 AMPK regulates the vacuolar proton-ATPase
via 14-3-3 proteins M.M. Al-bataineh, F. Gong, H. Li, A.M.
Marciszyn, V. Bhalla, K.R. Hallows and N.M. Pastor-Soler.
Univ. of Pittsburgh Sch. of Med. and Stanford Univ. Sch. of
Med.
376
A551 1109.12 A long form of the alpha subunit of the human
epithelial Na+ channel forms hyperactivated channels J.M.
Berman, C. Brand and M. Awayda. Univ. at Buffalo, SUNY.
A552 1109.13 Loss of carbonic anhydrase IX expression
impairs gastric mucosal defence against luminal acid T. Li, X.
Liu, A. Singh, B. Riederer, G. Gros, H. Bartels, B. Tuo and
U. Seidler. Hannover Med. Sch. and Affil. Hosp. of Zunyi Med.
Col., China.
A553 1109.14 Expression of the glycine transporter type
1 (GlyT-1A) is upregulated by ATF-4 following physiological
stress in human intestinal epithelial cells L.K.F. Fultang, A.
Howard and B.H. Hirst. Univ. of Newcastle, U.K.
A554 1109.15 Bacterial overload enhances duodenal anion
secretion via PKA upregulation Y. Akiba, D. Strugatsky, I. Kaji
and J.D. Kaunitz. UCLA and West Los Angeles VA Med. Ctr.
A555 1109.16 Actin depolymerizing factor but not cofilin-1 is
necessary to have a normal intestinal brush border L. Gao, R.
Sarker and M. Donowitz. Johns Hopkins Univ. Sch. of Med.
A556 1109.17 Anillin regulates cell-cell junction integrity by
organizing junctional accumulation of RhoA-GTP, F-actin, and
Myosin-2 A. Miller, C. Reyes, M. Jin, T. Arnold, E. Breznau,
R. Espino and A. Goryachev. Univ. of Michigan and Univ. of
Edinburgh.
A557 1109.18 Molecular support for high paracellular
absorption in the intestine of flying mammals E. CaviedesVidal, A. Brun, G. Fernández-Marinone, C. Gatica-Sosa, E.
Price, A. Amweg, H. Ortega and W.H. Karasov. CONICET,
Natl. Univ. of San Luis, Natl. Univ. of San Luis, Argentina, Univ.
of Wisconsin-Madison and Natl. Univ. del Litoral, Argentina.
1110.MECHANISMS OF INTESTINAL NUTRIENT,
WATER AND ELECTROLYTE TRANSPORT II
Poster
A558 1110.1 Curcumin relaxes cholecystokinin- or KClinduced tension in male guinea pig gallbladder strips through
multiple signaling pathways L. Kline and E. Karpinski. Univ.
of Alberta.
A559 1110.2 Measurements of the stomachs and
duodenums of fasted and sated rats M. Lorber. Georgetown
Univ. Sch. of Med.
A560 1110.3 Endogenous hydrogen sulfide decreases Rho
kinase and cGMP-specific phosphodiesterase (PDE5) activity
and induces relaxation of colonic smooth muscle A.D. Nalli, D.
Kendig, S. Mahavadi, J.R. Grider and K.S. Murthy. Virginia
Commonwealth Univ.
A561 1110.4 Effects of hibernation on gut motility in thirteenlined ground squirrels S. Liu, C. Brandenburg, L. Eliades, M.
Erlandson and S. Cooper. Univ. of Wisconsin-La Crosse.
A562 1110.5 Upregulation of RhoA/Rho kinase pathway
and downregulation of cGMP/PKG pathway in smooth muscle
impair peristaltic reflex and pellet propulsion in the colon of
diabetic mice D. Kendig, A.D. Nalli, S. Mahavadi, J.R. Grider
and K.S. Murthy. Virginia Commonwealth Univ.
A563 1110.6 Impaired serotonin transporter function in the
small intestine of mice on a high fat diet M. France, J. Galligan
and G. Swain. Michigan State Univ.
A564 1110.7 Butyrate increases and propionate decreases
the frequency of propulsive contractions in guinea pig proximal
colon N. Hurst, D.M. Kendig, K.S. Murthy and J.R. Grider.
TUESDAYPHYSIOLOGY
A565 1110.8 The velocity of pellet propulsion in guinea pig
distal colon is differentially modified by short-chain fatty acids
N. Hurst, D.M. Kendig, K.S. Murthy and J.R. Grider. Virginia
Commonwealth Univ.
A566 1110.9 Upregulation of L-type calcium channel function
in the colon of P/Q-type calcium channel deficient mice E.S.
Rodriguez-Tapia, D. Fried and J. Galligan. Michigan State
Univ.
A567 1110.10 High-fat diet alters neuromuscular transmission
and smooth muscle excitability in the mouse distal colon Y.
Bhattarai, D. Fried and J. Galligan. Michigan State Univ.
A568 1110.11 Increased expression of caveolin-1 is
associated with upregulation of the RhoA/Rho kinase pathway
and smooth muscle contraction in diabetes S. Mahavadi, A.D.
Nalli, D.P. Kumar, S. Bhattacharya, R. Zhou, J.R. Grider and
K.S. Murthy. Virginia Commonwealth Univ.
A569 1110.12 Enteric glial nitric oxide potentiates P2X7mediated neuron death I. Brown and B. Gulbransen. Michigan
State Univ.
A570 1110.13 Vagally-mediated
gastric
effects
of
catecholamines in stressed rats K. Browning, A.L. Fries and
R.A. Travagli. Penn State Col. of Med.
1111.BARRRIER FUNCTION AND REPAIR
Poster
A571 1111.1 Glial cell line-derived neurotrophic factor
(GDNF) promotes barrier maturation and wound healing
in intestinal epithelial cells in vitro M. Meir, L. Bergauer, S.
Flemming, C-T. Germer and N. Schlegel. Univ. of Wuerzburg.
A572 1111.2 Intestinal
epithelial
barrier
dysfunction
protects against pathogen translocation during initial infection
K.L. Edelblum, G. Singh, K. El Bissati, R. McLeod, B.A.
McCormick and J.R. Turner. Univ. of Chicago and Univ. of
Massachusetts Med. Sch.
A573 1111.3 Stabilisation of epithelial hypoxia-inducible
factor reverses colitis through accelerated restitution B.J.
Goggins, K. Minahan, A. Kostakis, R.A. Shalwitz, J.C.
Horvat and S. Keely. Sch. of Biomed. Sci. & Pharm., Univ.
of Newcastle and Hunter Med. Res. Inst., Australia and Aerpio
Therapeut., Cincinnati.
A574 1111.4 Modeling ZO-1-C-terminal domain exchange
at the membrane as a diffusion problem H.L. Nepomuceno,
C.T. Nguyen, K.H. Ogawa, J.R. Hasfura-Buenaga, E.C.
Balreira and J.M. King. Trinity Univ., San Antonio.
A575 1111.5 Ostrich oil failed to improve intestinal barrier
function following 5-fluorouracil-induced mucositis in rats K.Y.
Cheah, S. Mashtoub and G.S. Howarth. Univ. of Adelaide
and Women’s and Children’s Hosp., North Adelaide.
A576 1111.6 High resolution microscopy reveals claudin-18
as a basolateral and not a tight junction-associated protein
in stomach S.J. Hagen, L-H. Ang and Y. Zheng. Beth Israel
Deaconess Med. Ctr.
A577 1111.7 Stable PTPN2 knockdown in human intestinal
epithelial cell lines increases claudin-2 expression and
activation of MEK/ERK and PI3K signaling M. Krishnan and
D.F. McCole. Univ. of California, Riverside.
1112.GASTROINTESTINAL CANCER AND
METASTASIS
Poster
A578 1112.1 Risk factors of diseases gastrointestinal path
M. Imashev, A. Dubitsky and A. Fursov. Astana Med. Univ.,
Kazakhstan.
1113.GI AND LIVER EPITHELIAL JUNCTIONS
Poster
A579 1113.1 MLCK regulation of claudin 3 expression
contributes to IL1β mediated weakening of colonic epithelial
tight junctions R. Haines, R. Beard, S. Yuan and M. Wu. Univ.
of South Florida.
A580 1113.2 miR-93 downregulation of PTK6 attenuates
TNFα/IFNγ mediated of colonic epithelial barrier dysfunction R.
Haines, R. Beard, S. Yuan and M. Wu. Univ. of South Florida.
A581 1113.3 Effect of the bile acids unconjugated and
conjugated, chenodeoxycholic acid and deoxycholic acid,
on epithelial tight junction barrier function in a human colon
carcinoma cell line, T84 S. French, N. Framarin, A. Badar,
I. Akhtar, M. Ao, J. Domingue, M. Rao and J. Sarathy.
Benedictine Univ. and Univ. of Illinois at Chicago.
1114.GI HORMONES, PEPTIDES AND RECEPTORS
Poster
A582 1114.1 Ligand-directed activation of extracellular
signal-regulated kinases (ERK1/2) in enteric neurons C.
Duraffourd, E. Kumala, L. Anselmi, N. Brecha and C.
Sternini. UCLA.
A583 1114.2 Ghrelin and des-acyl ghrelin stimulate glucose
output in mouse primary hepatocytes B.P. Callaghan, B.
Hunne, V. Montanholi Martins, J. Brock and J.B. Furness.
Univ. of Melbourne.
A584 1114.3 Glp2r is required for postprandial glycemic
control X. Shi, S. Wen, S. Chacko, L. Chan and X. Guan.
Baylor Col. of Med.
1115.LIVER PHYSIOLOGY AND PATHOPHYSIOLOGY
Poster
A585 1115.1 Sirtuin 1 induces autophagy to suppress liver
ischemia/reperfusion injury in mice T.G. Biel, J.A. FloresToro, J.W. Dean, B.K. Law, I. Zendejas, K.E. Behrns and
J-S. Kim. Univ. of Florida.
377
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PHYSIOLOGYTUESDAY
A586 1115.2 Age-related activation of the hepatic unfolded
protein response and inflammasome are reduced by trehalose
treatment M. Pagliassotti, T. LaRocca, Y. Wei, D. Wang, W.
Hudson, M. Zigler and D. Seals. Colorado State Univ. and
Univ. of Colorado Boulder.
A587 1115.3 Nitric oxide synthase inhibition exacerbates
liver injury in an obese rat model of NAFLD R.D. Sheldon, J.
Padilla, N.T. Jenkins, M.H. Laughlin and R.S. Rector. Univ.
of Missouri-Columbia, Harry S Truman VA Hosp. and Univ. of
Georgia.
A588 1115.4 Activation of IKK2-NF-κB in adult mouse liver
produces a cytoprotective gene expression profile without
signs of inflammation, insulin resistance, or fibrosis H. Lu, X.
Lei and Q. Zhang. SUNY Upstate Med. Univ.
A589 1115.5 An emerging link between the negative EGFR
feedback regulator Mig6 and hepatic glucose production A.J.
Lutkewitte. Indiana Univ. Sch. of Med.
A590 1115.6 Hepatic stellate cells orchestrate clearance
of necrotic cells from the liver by modulating macrophage
phenotype B.L. Copple, C.E. Rockwell and J.P. Luyendyk.
Michigan State Univ.
1116.ALCOHOLIC AND NONALCOHOLIC FATTY
LIVER DISEASE
Poster
A591 1116.1 Histology of liver oxidative stress in an obese
mouse model of nonalcoholic fatty liver disease treated with Ω3
fatty acids, TNFα-receptor blocker, or curcumin A. Likhitsup,
L. Alba, B. Herndon, A. Mansour, H. Zia and A. Molteni.
Univ. of Missouri-Kansas City Sch. of Med.
A592 1116.2 Umbelliferone supplementation attenuates
alcohol-induced hepatic steatosis by regulating PPARα- and
SREBP-1c pathway in rats M-O. Sim, H-I. Lee, J.R. Ham, R.Y.
Choi, S.J. Kim, K-I. Seo, M-J. Kim and M-K. Lee. Sunchon
Natl. Univ. and Suseong Col., South Korea.
A593 1116.3 High fat diet alters homocysteine metabolism
and hydrogen sulfide biosynthesis in mice L.K. Sarna, S-Y.
Hwang, Y.L. Siow and K. O. St. Boniface Hosp. Res. Ctr.,
Winnipeg, Univ. of Manitoba and Agr. Agri-Food Canada,
Winnipeg.
A594 1116.4 The role of mitofusin 2 in saturated fatty acid
induced ER stress in H4IIE liver cells G. Moran, Y. Wei, D.
Wang and M. Pagliassotti. Colorado State Univ.
A595 1116.5 Weight loss alone does not fully resolve nonalcoholic steatohepatitis markers in western diet fed Ldlr-/mice: a pilot study K.A. Lytle and D.B. Jump. Oregon State
Univ.
A596 1116.6 Pterostilbene, a natural analogue of resveratrol,
decreases hepatic lipid deposition by increasing triacylglycerol
hydrolases activity C.C.L. Moreira, A.H. Rodrigues, L.M.D.S.
Cordeiro, É.G. Mario, D.D. Rosa and L.M. Botion. Fed. Univ.
of Minas Gerais and Fed. Univ. of Viçosa, Brazil.
A597 1116.7 The role of protein synthesis in saturated fatty
acid-induced ER stress in H4IIE liver cells A.L. Estrada, F.
Peelor, D. Wang, Y. Wei, K. Hamilton, B.F. Miller and M.J.
Pagliassotti. Colorado State Univ.
378
A598 1116.8 The impact of P-selectin deficiency on obesityassociated non-alcoholic fatty liver disease C.Y. Kuo, Y.J. Day
and L.M. Hung. Chang Gung Univ. and Chang Gung Mem.
Hosp., Linkou, Taiwan.
A599 1116.9 Evaluation of novel inflammation biomarkers
GlycA and GlycB in overweight and obese adolescents with
NAFLD R. Jin, J. Otvos, N-A. Le and M. Vos. Emory Univ.,
LipoSci. Inc., Raleigh and Atlanta VA Med. Ctr.
A600 1116.10 H1-antihistamines exacerbate high fat dietinduced fatty liver disease in wild type but not in apolipoprotein
E-knockout mice V. Vimala Raveendran, K.M. Kassel, D.D.
Smith, R. Cherian, G.A. Reed, C.A. Flynn, J.P. Luyendyk
and K.N. Dileepan. Univ. of Kansas Med. Ctr., VA Med. Ctr.,
Kansas City, MO, Michigan State Univ. and Univ of Kansas
Med. Ctr.
A601 1116.11 Low copper and dietary sucrose drive fibrosis
pathways in a rat model of non-alcoholic fatty-liver disease
S.L. Tallino and J. Burkhead. Univ. of Alaska Anchorage.
A602 1116.12 Circadian clock mediates ER stress signaling
in alcoholic fatty liver H. Tsuchiya, Y. Zhang, S. Lee, R.
Smalling and L. Wang. Univ. of Utah Sch. of Med.
A603 1116.13 Iron-mediated upregulation of M1 and
downregulation of M2 programs in macrophages suggests a
role for iron in the pathogenesis of non-alcoholic steatohepatitis
P. Handa, V. Morgan-Stevenson and K.V. Kowdley. Benaroya
Res. Inst., Seattle.
1117.METABOLIC DISEASE: GI AND LIVER
FUNCTION
Poster
A604 1117.1 Secretory and absorptive dysfunctions in ob/
ob mouse jejunum are sex-dependent L. Al-Nakkash and L.
Leung. Midwestern Univ., AZ.
1118.MICROBIOME OF THE GI TRACT
Poster
A605 1118.1 Sucralose causes a concentration dependent
metabolic inhibition of the gut flora Bacteroides, B. fragilis and
B. uniformis not observed in the Firmicutes, E. faecalis and C.
sordellii S.M. Rettig, J.E. Tenewitz, G.A. Ahearn and C.B.
Coughlin. Univ. of North Florida.
A606 1118.2 Drug-induced constipation alters gut microbiota
stability leading to physiological changes in the host K. Touw,
Y. Wang, V. Leone, A. Nadimpalli, H. Nathaniel, F. Gianrico,
P. Kashyap and E. Chang. Univ. of Chicago and Mayo Clin.
A607 1118.3 HLA DQ/DR prevalence and microbiota
disturbance in northwestern Mexican children with type 1
diabetes M.E. Mejia-Leon, J.S. Petrosino, N. Ajami, M.G.
Domínguez-Bello and A.M. Calderon de la Barca. Ctr. for
Food Res. and Develop. AC, Hermosillo, Mexico, Baylor Col.
of Med. and NYU Sch. of Med.
A608 1118.4 Cultured milk bacterial isolates survive well
in digestive tract conditions and could be potential probiotic
candidates B.B. Boyiri, J. Kotala, B. Lampson and E.M.
Onyango. East Tennessee State Univ.
TUESDAYPHYSIOLOGY
1119.ORGANOID CULTURE SYSTEMS: AN
INNOVATIVE RESEARCH TOOL FOR
THE STUDY OF GASTROINTESTINAL
DEVELOPMENT PHYSIOLOGY AND DISEASE
A609 1119.1 Gastric antral organoids are sustained by
intrinsic Notch signaling G.B. Gifford, E.S. Demitrack, J.R.
Spence, D.M. Simeone and L.C. Samuelson. Univ. of
Michigan.
A610 1119.2 Spontaneous maturation of human colonic
organoids E. Rodrigues, L. Slobbe, M. Schultz and G. Butt.
Univ. of Otago, New Zealand.
A611 1119.3 Esophageal squamous cell carcinoma model of
3D organotypic tissue culture system with genetic modification
of epithelial growth factor receptor and p120-catenin X. Yang,
H.L. Lehman, R.T. Bruggeman, X. Nie and D.B. Stairs. Penn
State Hershey Med. Ctr.
A612 1119.4 CagA+ Helicobacter pylori induces proliferation
and expression of Sonic hedgehog in fundic organoid model
M.A. Schumacher, E. Aihara, R. Feng and Y. Zavros. Univ.
of Cincinnati.
A613 1119.5 Mesenchymal stem cells isolated from
the bone marrow of mice with gastritis induce epithelialmesenchymal transition of gastric organoids J. Turner, R.
Feng, J.M. Donnelly, M.A. Schumacher and Y. Zavros. Univ.
of Cincinnati and USDA, Houston.
A614 1119.6 ErbB4 deletion compromises the murine small
intestinal stem cell niche and sensitizes the epithelium to TNFinduced apoptosis D. Almohazey, J.K. Bernard and M.R.
Frey. Children’s Hosp. Los Angeles.
A619 1120.5 Global DNA methylation and extracellular
matrix remodeling in aortic smooth muscle versus endothelial
cells in hyperhomocysteinemia N. Narayanan, S. Kundu, S.
Givvimani, S.B. Pushpakumar, R. Kulkarni and S.C. Tyagi.
A620 1120.6 Role of JMJD3 and histone modifications in
intermittent hypoxia-induced neuroinflammation S.M. Smith
and J.J. Watters. Univ. of Wisconsin-Madison.
A621 1120.7 Age and SPARC dependent cardiac collagen
changes H. Toba, L.E. de Castro Brás, S.T. Weintraub,
Y-F. Jin, A.D. Bradshaw and M.L. Lindsey. San Antonio
Cardiovasc. Proteomics Ctr, Univ. of Mississippi Med. Ctr.,
Kyoto Pharmaceut. Univ., Univ. of Texas Hlth. Sci. Ctr. at San
Antonio, Univ. of Texas at San Antonio,Ralph H. Johnson VA
Med. Ctr., Med. Univ. of South Carolina and G.V. (Sonny)
Montgomery VA Med. Ctr., Jackson, MS.
A622 1120.8 Base-resolution maps of 5-methylcytosine and
5-hydroxymethylcytosine in Dahl salt-sensitive rats Y. Liu,
P. Liu, C. Yang, A.W. Cowley and M. Liang. Med. Col. of
Wisconsin.
A623 1120.9 Epigenetic
impact
of
curcumin-primed
exosomes in amelioration of blood-brain barrier dysfunction A.
Kalani, P.K. Kamat, A. Familtseva, S.C. Tyagi and N. Tyagi.
A624 1120.10 Improving post-traumatic stress disorder
biomarkers through matching patients and controls on multiple
criteria D. Donohue, S-A. Miller, E. Gupta, R. Yang, A.
Guatam, R. Hammamieh and M. Jett-Tilton. U.S. Army Ctr.
for Envrn. Hlth. Res., Fort Detrick, MD and Walkersville H.S.,
MD.
A625 1120.11 DNA methylation differences in CD16+ cells
between normal weight and obese women of childbearing
age N.M. Hohos, H.J. Park, D. Shade, D. Hausman, R.B.
Meagher, A.K. Smith, M.A. Della-Fera, L.B. Bailey and C.A.
Baile. Univ. of Georgia and Emory Univ. Sch. of Med.
1120.EPIGENETICS, EPIGENOMICS
1121.GENETICALLY-ENGINEERED MODELS
Poster
Poster
Poster
A615 1120.1 Chronic ethanol intake leads to differential
effects on the multivalent epigenetic state in liver B. Patra,
L. Kuttippurathu, J.B. Hoek and R. Vadigepalli. Thomas
Jefferson Univ.
A616 1120.2 High salt diet causes epigenetic modifications
and suppresses endothelial progenitor cell function J.R.
Karcher, B.R. Hoffmann, P. Liu and A.S. Greene. Med. Col.
of Wisconsin.
A617 1120.3 Dietary supplementation with polyunsaturated
fatty acid during pregnancy modulates DNA methylation at
IGF2/H19 imprinted genes and growth of infants I. Romieu,
H. Lee, A. Barraza, C. Biessy, T. Duarte-Salles, P. Sly, U.
Ramakrishnan, J. Rivera Dommarco and Z. Herceg. Intl.
Agcy. for Res. on Cancer, Lyon, Natl. Inst. of Publ. Hlth. México
City, Queensland Children’s Med. Res. Inst., Herston, Emory
Univ. and Natl. Inst. of Publ. Hlth. Cuernavaca.
A618 1120.4 The impact of maternal in utero environment
on salt-induced hypertension in the SS rat A.M. Geurts, D.
Mattson, P. Liu, M. Skelton, T. Kurth, J. Klotz, M. Grzybowski,
M. Liang and A.W. Cowley. Med. Col. of Wisconsin.
A626 1121.1 Reversible transgene expression in mice: now
you see it, now you don’t K.I. Matthaei, S.K. Morton, D.J.
Chaston, B.K. Baillie and C.E. Hill. John Curtin Sch. of Med.
Res., Australian Natl. Univ.
A627 1121.2 Initial characterization of leptin receptor
knockout Dahl salt-sensitive rats K. McPherson, T.N. White,
A. Johnson, A.M. Geurts, H.J. Jacob, M.R. Garrett and
J.M. Williams. Univ. of Mississippi Med. Ctr. and Med. Col. of
Wisconsin.
A628 1121.3 Research community driven development to
genetically modify rat models for heart, lung, blood and sleep
disorders J. Lazar, M.R. Dwinell, A.J. Geurts, D.L. Mattson
and H.J. Jacob. Med. Col. of Wisconsin.
A629 1121.4 Ectoderm specific deletion of Jak2 results in
developmental and neuronal abnormalities S.O. Park, K-U.
Wagner and P. Sayeski. Univ. of Florida Col. of Med. and Univ.
of Nebraska Med. Ctr.
379
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PHYSIOLOGYTUESDAY
1122.ION TRANSPORT: GENES AND FUNCTION
Poster
A630 1122.1 Bestrophin-3 is expressed in the mouse
intestine E. Eliasson, V. Golubinskaya and H. Nilsson. Univ.
of Gothenburg.
A631 1122.2 In vivo microelectrode assessment of NBCe2
activity in the distal nephron during an acid load y. yuan, h.
li, D. Wen, T. Boettger and S.C. Sansom. Univ. of Nebraska
Med. Ctr. and Max Planck Inst. for Heart and Lung Res., Bad
Nauheim.
A632 1122.3 NHE8 in human conjunctival epithelial cells:
expression and regulation Y. Zhao, J. Li, M. Wang, F. Ghishan
and H. Xu. Univ. of Arizona.
1123.VASCULAR DISEASE: GENES AND FUNCTION
Poster
A633 1123.1 Acute tetrahydrobiopterin restores endothelial
function in patients with COPD R.A. Harris, N. Seigler, K.
Halasan, S. Livieratos, T. Dillard and L. Bass. Univ. of Ulster,
Jordanstown and Georgia Regents Univ.
A634 1123.2 Prostaglandin E2 receptor EP4 signaling in
vascular smooth muscle cells decreases aortic elasticity Y.
Ichikawa, U. Yokoyama and Y. Ishikawa. Yokohama City
Univ.
A635 1123.3 Disrupted gene expression in human cerebral
cavernous malformations T. Shishoian and R. Stockton.
California State Univ., Dominguez Hills and Los Angeles
Biomed. Res. Inst.
1124.PHYSIOLOGICAL GENOMICS OF KIDNEY
DISEASE
Poster
A636 1124.1 Activation of Gα12 regulates ectodomain
shedding of cadherins in renal epithelial cells J. Xu, Y. Wu,
S. Li, Y-C. Hsieh, T. Kong and T. Lu. Harvard Med. Sch.,
Brigham and Women’s Hosp.
1125.CENTRAL NERVOUS SYSTEM
Poster
A637 1125.1 Analysis of cerebrospinal fluid flow in
hydrocephalic mouse models of primary ciliary dyskinesia K.
Johnson, R. Finn and L. Lee. Sanford Res., Sioux Falls, SD.
380
A638 1125.2 Cortical voluntary activation adjustments
induced by non-exhausting eccentric exercise O. Girard,
S. Racinais, S. Banzet, N. Koulmann, M. Chennaoui, C.
Drogou and H. Chalabi. Aspetar-Qatar Orthopaed. and
Sports Med. Hosp., Doha and Biomed. Res. Inst. of the Armed,
Brétigny-sur-Orge.
A639 1125.3 The role of Toll-like receptor 2 in macrophage
activation K.R. Jang and J. Gensel. Univ. of Kentucky.
A640 1125.4 Inhibition of endoplasmic reticulum function
in PVN by thapsigargin increases neuronal excitability and
sympathetic nerve activity R.A. Larson, L. Gui, A. Chapp, M.
Huber, J. Zhu, Z. Cheng, Z. Shan and Q-H. Chen. Michigan
Tech Univ., Nantong Univ., China and Univ. of Central Florida.
A641 1125.5 Ethanol metabolite increases activity of CeA
neurons and requires activation of local NMDA receptors A.
Chapp, R.A. Larson, M. Huber, J.R. Carter and Q-H. Chen.
Michigan Tech Univ.
A642 1125.6 The effects of age on multiscale entropy
measurement of neurophysiological signal complexity M.J.
Tobia, M.D. Meadowcroft, P. Karunanayaka and Q.X. Yang.
Penn State Hershey Med. Ctr.
1126.CNS CONTROL OF FEEDING AND
METABOLISM
Poster
A643 1126.1 Orexin A in the ventrolateral preoptic area
increases feeding and spontaneous physical activity A.
Rezaimalek and J.A. Teske. Univ. of Arizona and Minneapolis
VA Healthcare Syst.
A644 1126.2 Orexinergic activation of medullary premotor
neurons mediates the adrenal sympathoexcitation to
hypothalamic glucoprivation W.S. Korim, L. Bou-Farah, S.
McMullan and A.J.M. Verberne. Univ. of Melbourne and
Macquarie Univ., Australia.
A645 1126.3 Glucose responsive neurons in the nucleus of
the solitary tract are responsive to nesfatin-1 A. Mimee and
A.V. Ferguson. Queen’s Univ., Canada.
A646 1126.4 Knockdown of tyrosine hydroxylase in the
nucleus of the solitary tract prevents attenuated body weight
gain and blunts neuronal activation in the hypothalamus
following chronic intermittent hypoxia T.P. Nedungadi, C.S.
Bathina and S.W. Mifflin. Univ. of North Texas Hlth. Sci. Ctr.
A647 1126.5 Chronic intermittent hypoxia is associated
with elevated pro-opiomelanocortin mRNA and reduced
microRNA-375 levels in arcuate nucleus of hypothalamus T.P.
Nedungadi and J.T. Cunningham. Univ. of North Texas Hlth.
Sci.
A648 1126.6 Brain-derived neurotrophic factor exerts
depolarizing effects on hypothalamic paraventricular nucleus
neurons W. McIsaac and A.V. Ferguson. Queen’s Univ.,
Canada.
A649 1126.7 Neuropeptide Y1 receptor is a key element
in stress response to food deprivation E.L. Dimitrov, M.G.
DeJoseph and J.H. Urban. Rosalind Franklin Univ.
A650 1126.8 Neuropeptide
Y
signaling
from
the
hypothalamus inhibits sympathetic outflow to brown adipose
tissue through GABA inhibition of the rostral medullary raphe
Y. Nakamura and K. Nakamura. Kyoto Univ. and JST,
Kawaguchi, Japan.
TUESDAYPHYSIOLOGY
A651 1126.9 Leptin receptor deletion from POMC neurons
increases susceptibility to high fat diet-induced obesity B.B.
Bell, S.M. Harlan, D.A. Morgan and K. Rahmouni. Univ. of
Iowa.
A652 1126.10 Bbs1 gene deletion from the leptin receptorcontaining neurons causes obesity D.F. Guo, V.C. Sheffield
and K. Rahmouni. Univ. of Iowa.
A653 1126.11 Regulation of leptin receptor expressing
neurons in the brainstem by TRPV1 A. Zsombok, Y. Jiang,
I.J. Anwar, K. Rezai-Zadeh and H. Muenzberg-Gruening.
Tulane Univ. and Pennington Biomed. Res. Ctr., Baton Rouge.
A654 1126.12 Effects of weight-reducing chronic vagal nerve
stimulation on cardiovascular, autonomic, and respiratory
functions H.M. Stauss, D.A. Morgan and K. Rahmouni. Univ.
of Iowa.
A655 1126.13 The brain renin-angiotensin system suppresses
digestive efficiency B.J. Weidemann, N.K. Littlejohn, R.S.
Cole and J.L. Grobe. Univ. of Iowa.
A656 1126.14 Circadian variation in gene expression in the
medulla of DOCA/salt hypertensive rats M. Hernandez, B.
Erdos and L. Hayward. Univ. of Florida.
A657 1126.15 Brain ACE2 overexpression stimulates food
intake and promotes glucose intolerance in mice H. Xia, K.H.
Chhabra, N.K. Littlejohn, N.A. Pearson, J.L. Grobe and E.
Lazartigues. LSU Hlth. Sci. Ctr., New Orleans and Univ. of
Iowa.
A658 1126.16 Relief of endoplasmic reticulum stress in the
brain subfornical organ rescues high fat diet-induced nonalcoholic fatty liver disease J.A. Horwath, C.N. Young, S.D.
Butler, A.L. Mark and R.L. Davisson. Cornell Univ., Weill
Cornell Med. Col. and Univ. of Iowa.
A659 1126.17 WFS1-deficient mice have alterations in energy
metabolism: role of TRPM8 receptors S. Koks, M. Ivask and
M. Ehrlich. Univ. of Tartu, Estonia.
A660 1126.18 Hydrogen sulfide promotes mitochondrial
biogenesis through PPARγ activation in intra-cerebral
administration of homocysteine P.K. Kamat, A. Kalani, S.C.
Tyagi and N. Tyagi. Univ. of Louisville.
A661 1126.19 Neuro-glio-vascular dysfunction and epigenetic
remodeling in diabetic stroke A. Kalani, P.K. Kamat, S.C.
Tyagi, N. Metreveli and N. Tyagi. Univ. of Louisville.
A662 1126.20 α7 Nicotinic acetylcholine receptors induced an
increase in intracellular calcium in supraoptic nucleus neurons
Z. Song. Univ. of Colorado, Aurora.
1127.NEUROGLIAL INTERACTIONS
Poster
A663 1127.1 The influence of fetal cellular therapy on
the functions’ restoration of central nervous system at rats
after fatal hypobaric hypoxia Z. Aitbayeva, D. Tazhibaeva,
N. Kabdualieva, G. Beglarova, L. Ermentaeva and A.
Alipbekova. Astana Med. Univ. and Kazakh Natl. Med. Univ.,
Kazakhstan.
A664 1127.2 Sustained hypoxia alters expression and
function of excitatory amino acid transporters in the nucleus of
the solitary tract M.P. Matott, C. Schramm, H.A. Dantzler and
K.D. David. Univ. of Missouri-Columbia.
A665 1127.3 Neuronal-activity-dependent
hippocampal
glycolysis mediated by dopamine T. Matsui, S. Soya, K.
Kawanaka and H. Soya. Niigata Univ. of Hlth. and Welfare
and Univ. of Tsukuba.
A666 1127.4 Neuronal networks on the nano alumina
templates A. Islam and L. Menon. Northeastern Univ.
1128.NEURONAL EXCITABILITY/NEUROPLASTICITY
Poster
A667 1128.1 Characterization of changes in muscle afferent
response to stretch following inflammation in male and
female mice A. Allawala, S. Behnke, D. Zaytseva and K.A.
Wilkinson. San Jose State Univ.
A668 1128.2 Inhibition of a hyperpolarization-activated
inward current (Ih) facilitates cold-activation of locus coeruleus
neurons of bullfrogs, Lithobates catesbeianus J.M. Santin,
K.C. Watters and L.K. Hartzler. Wright State Univ.
A669 1128.3 Computational modeling of the effects of
temperature on chemosensitive locus coeruleus neurons from
bullfrogs R.W. Putnam, M.C. Quintero, J.M. Santin, J.M.
Cordovez and L.K. Hartzler. Wright State Univ. and Univ. de
los Andes, Colombia.
1129.NEUROTRANSMISSION AND SIGNALING
MOLECULES
Poster
A670 1129.1 Evidence of decreased dopamine receptormediated control of gap junction coupling in the inner nuclear
layer of the diabetic Ins2Akita mouse retina L.A. Fortepiani,
M. Pyarali, N.P. Akimov, Z. Zhang, C.P. Ribelayga and R.C.
Rentería. Univ. of the Incarnate Word, San Antonio, Univ. of
Texas Hlth. Sci. Ctr. at San Antonio and Univ. of Texas Hlth.
Sci. Ctr. at Houston.
A671 1129.2 Nesfatin-1
influences
the
excitability
of subfornical organ neurons through actions on the Ik
conductance M. Kuksis and A.V. Ferguson. Queen’s Univ.,
Canada.
A672 1129.3 Prolactin influences the excitability of
subfornical organ neurons E.A. Black, D.R. Grattan and A.V.
Ferguson. Queen’s Univ., Canada and Univ. of Otago, New
Zealand.
A673 1129.4 Hydrogen sulfide decreases a slow rectifying
potassium conductance in nucleus tractus solitarius neurons
R. Malik and A.V. Ferguson. Queen’s Univ., Canada.
A674 1129.5 Ehs-1 is required for the expulsion step of
the Caenorhabditis elegans defecation motor program N.F.
Freeburg and M. Peters. Oberlin Col.
A675 1129.6 Calcium signaling and neuropeptide secretion
in the expulsion step of the Caenorhabditis elegans defecation
motor program S.J. McCright and M.A. Peters. Oberlin Col.
A676 1129.7 Synaptic and neurochemical characteristics of
the nucleus tractus solitarius pars centralis neurons T. Babic,
K.N. Browning and R.A.A. Travagli. Penn State Hershey Col.
of Med.
381
T
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PHYSIOLOGYTUESDAY
A677 1129.8 An intestinal gap-junction protein is needed for
normal acetylcholine response in Caenorhabditis elegans G.M.
Moore, P. Hammer and M. Peters. Oberlin Col.
A678 1129.9 Effects of pregabalin on D-serine content and
NMDA receptor-mediated synaptic transmission in the mouse
spinal cord R. Matsuzawa, T. Takasusuki, M. Maekawa, S.
Yamaguchi and Y. Hori. Dokkyo Med. Univ., Japan.
A679 1129.10 Expression of NaV1.9 channels by muscle
afferent neurons T.L. Marler and K.S. Elmslie. A. T. Still Univ.
1130.CENTRAL AUTONOMIC REGULATION
Poster
A680 1130.1 The hypoxia-sensitivity of RVLM sympathetic
premotor neurons is mediated by glial ATP release L. Bou
Farah and S. McMullan. Macquarie Univ., Australia.
A681 1130.2 Effect of combined V1a/V1b vasopressin
receptor blockade within the paraventricular nucleus on
neurocardiovascular responses N.F. Rossi, C. Li, H. Chen
and M. Maliszewska-Scislo. Wayne State Univ. and John D.
Dingell VA Med. Ctr.
A682 1130.3 Endocannabinoid effects on neuronal function
in the NTS of hypertensive rats F.A. Hopp, C. Dean and J.L.
Seagard. Zablocki VA Med. Ctr. and Med. Col. of Wisconsin.
A683 1130.4 Blockade of mineralocorticoid receptors in the
dorsal hindbrain enhances baroreflex sensitivity I.M. Backes,
R. Clifton, D. Scheuer and G.K. Adler. Univ. of Florida and
Brigham and Women’s Hosp., Harvard Med. Sch.
A684 1130.5 Modulation of arousal state and temperature is
unaltered but activity is increased in tryptophan hydroxylase 2
knockout mice J.Z. Solarewicz, C.R. Richardson, M. AngoaPérez, D.M. Kuhn and J.H. Mateika. John D. Dingell VA Med.
Ctr. and Wayne State Univ.
A685 1130.6 Sociopsychological
stress
activates
hypothalamo-medullary neurons that drive brown adipose
tissue thermogenesis and hyperthermia N. Kataoka and K.
Nakamura. Kyoto Univ. and PREST, JST, Kawaguchi, Japan.
A686 1130.7 Effect of an emetic gastrointestinal input on the
processing of labyrinthine inputs by cerebellar rostral fastigial
nucleus neurons M.E. Catanzaro, D.J. Miller, L.A. Cotter,
A.A. McCall and B.J. Yates. Univ. of Pittsburgh.
A687 1130.8 Hyperosmotic stimulation elicits a purinergicglutamatergic coupling in PVN presympathetic neurons H.
Candido Ferreira Neto, V.R. Antunes and J.E. Stern. Univ.
of São Paulo and Georgia Regents Univ.
A688 1130.9 Enhanced leptin-TRPC signaling in the
hypothalamus contributes to the exaggerated sympathoexcitation in type 2 diabetic rats H. Zheng, X. Liu, Y. Li and
K.P. Patel. Univ. of Nebraska Med. Ctr.
A689 1130.10 Renal denervation attenuates the enhanced
activation of the paraventricular nucleus in heart failure:
restoring nNOS! K.P. Patel, X. Liu, T.L. Llewellyn and H.
Zheng. Univ. of Nebraska Med. Ctr.
A690 1130.11 Effect of liposome entrapped-GABA on the
expression of nNOS and GABAA receptors in neurons G.C.
Vaz, N.M. Sharma, H. Zheng, A.P.O. Bahia, M.C. Zimmerman,
F. Frezard, M.A. Fontes and K.P. Patel. Fed. Univ. of Minas
Gerais, Brazil and Univ. of Nebraska Med. Ctr.
382
A691 1130.12 Blockade of mineralocorticoid receptors in the
dorsal hindbrain inhibits stress-induced hypertension in rats
R.R. Clifton, I. Backes and D.A. Scheuer. Univ. of Florida.
A692 1130.13 Systemic inhibition of AT1 receptors does not
alter respiratory-sympathetic synchronization in anesthetized
rats M.T. Favero, M.F. Menezes, K. Yamamoto, P.M. de
Paula, J.V. Menani and S. Mifflin. São Paulo State Univ.,
Araraquara and Univ. of North Texas Hlth. Sci. Ctr.
A693 1130.14 Brain endoplasmic reticulum stress mediates
sympathetic and hemodynamic responses to blood-borne
TNF-α in rats Y. Yu, Z-H. Zhang, S-G. Wei and R.B. Felder.
Univ. of Iowa and VA Med. Ctr.
A694 1130.15 Acute intermittent hypoxia induces sympathetic
long-term facilitation but does not alter synchronization
between phrenic and sympathetic nerves K. Yamamoto, P.M.
Lalley and S. Mifflin. Univ. of North Texas Hlth. Sci. Ctr. and
Univ. of Wisconsin-Madison.
A695 1130.16 HIF-1α increases sympathoexcitation via
upregulation of NMDA receptors in the PVN during heart failure
N.M. Sharma, C.J. Cunningham, X. Liu, H. Zheng and K.P.
Patel. Univ. of Nebraska Med. Ctr.
A696 1130.17 RVLM sympathetic premotor neurons are
not synaptically linked to each other L. Bou Farah and S.
McMullan. Macquarie Univ., Australia.
A697 1130.18 A nigro-vagal pathway controls gastric motility
L. Toti and R.A.A. Travagli. Penn State Hershey Col. of Med.
A698 1130.19 Neuronal plasticity within the medullary
dorsal horn: the nasopharyngeal response returns 3 days
after bilateral sectioning of the anterior ethmoidal nerve P.F.
McCulloch and K.M. DiNovo. Midwestern Univ., IL.
A699 1130.20 Reduced GABAergic synaptic transmission in
the nucleus tractus solitarius in Mecp2-null mice C-Y. Chen,
Y-C. Lin, M.A. Rogawski, C-C. Lien, I. Maezawa and L-W.
Jin. Univ. of California, Davis and Natl. Yang-Ming Univ.,
Taiwan.
A700 1130.21 Mechanisms of chronic intermittent hypoxiainduced enhancement of paraventricular nucleus glutamatergic
tone M. Bardgett, Q. Guo and G. Toney. Univ. of Texas Hlth.
Sci. Ctr. at San Antonio.
A701 1130.22 Selective expression of an angiotensin-(1-7)producing fusion protein in the brain decreases blood pressure
D.T. Alves, P.S. Guimaraes, M. Todiras, M. Bader, R.A.S.
Santos and M.J. Campagnole-Santos. Fed. Univ. of Minas
Gerais, Brazil and Max Delbruck Ctr. for Molec. Med., Berlin.
A702 1130.23 Behavioral activation treatment increases
parasympathetic activity in veterans L.A. Reyes, L. McAndrew,
K. Ray, M. Blatt, B. Ghobreal, A. Acosta and J.M. Serrador.
VA New Jersey Hlth. Care Syst., East Orange and Rutgers
Biomed. and Hlth. Sci., Newark.
1131.NEURAL CONTROL OF VISCERAL AND
METABOLIC FUNCTION
Poster
A703 1131.1 Role of histamine in the sensory motor
integration of gill lateral cell cilia in the bivalve mollusc,
Crassostrea virginica P. Akande, J. Duncan, E.J. Catapane
and M.A. Carroll. Medgar Evers Col., Brooklyn.
TUESDAYPHYSIOLOGY
A704 1131.2 Intraductal applications of lidocaine attenuate
the severity of post-ERCP acute pancreatitis M.P. Skolka, T.
Babic and R.A. Travagli. Messiah Col., PA and Penn State
Col. of Med.
A705 1131.3 Monoamine innervation of vagal motor neurons
retrogradely labelled from the subdiaphragmatic oesophagus
I.J. Llewellyn-Smith, L. Travis, D.I. Watson, P.G. Dinning,
N.J. Spencer, A.Y. Fong, C. Menuet and A.M. Allen. Flinders
Univ., Australia and Univ. of Melbourne.
A706 1131.4 Sensory re-innervation of the rat uterus
postpartum I.J. Llewellyn-Smith and G.J.E. Gnanamanickam.
Flinders Univ., Australia.
A707 1131.5 Cystitis-induced bladder overactivity is
prevented by inhibition of N-methyl-d-aspartate receptormediated inflammatory responses in the urinary bladder M.
Liu, S. Shen, J.R. Grider and L. Qiao. Virginia Commonwealth
Univ.
A708 1131.6 Vagal nerve stimulation can elicit both
activation and inhibition of brown adipose tissue sympathetic
nerve activity S.F. Morrison, C.J. Madden and D. Tupone.
A709 1131.7 A neurophysiological study of the medullary
sympathetic pathway to the adrenal gland A.J. Verberne, W.S.
Korim and A. Sabetghadam. Univ. of Melbourne.
A709A 1131.8 The number of chewing affects postprandial
splanchnic blood flow. Y. Hamada, H. Kashima and N.
Hayashi. Grad. Sch. of Decision Sci. and Technol., Tokyo Inst.
of Technol. and Sch. of Hlth. Sci., Prefect. Univ. of Hiroshima.
1132.NEURAL MECHANISMS IN CARDIOVASCULAR
DISEASE
A717 1132.8 Activities in a single sensory fiber of the aortic
depressor nerve were derived from multiple encoders J. Liu,
N. Song, S. Tian, J. Guardiola, M. Proctor and J. Yu. Robley
Rex VA Med. Ctr. and Univ. of Louisville.
A718 1132.9 Hypertension impairs spontaneous baroreflex
heart rate control during exercise and muscle metaboreflex
activation R.A. Augustyniak, M.D. Spranger, R. AbuHamdah, J. Kaur, R.L. Hammond, J.A. Sala-Mercado, M.
Ichinose and D.S. O’Leary. Wayne State Univ. Sch. of Med.,
Edward Via Col. of Osteo. Med. - Carolinas Campus and Sch.
of Business Admin., Meiji Univ., Japan.
A719 1132.10 Rheumatoid arthritis and autonomic function
A.M. Adlan, A. Shantsila, G. Kitas, J.F. Paton, G.Y. Lip and
J.P. Fisher. Sch. of Sport, Exercise and Rehabil. Sci., Univ. of
Birmingham,Russells Hall Hosp., Dudley, U.K., Sch. of Physiol.
& Pharmacol., Univ. of Bristol and Univ. of Birmingham, City
Hosp.
A720 1132.11 Acute mild stress induces cardiac arrhythmias
and sudden death in sarcoglycan delta deficient mice, a model
of muscular dystrophy R. Sabharwal and M.W. Chapleau.
Univ of Iowa and VA Med. Ctr.
A721 1132.12 Pathophysiology of oscillatory breathing during
sleep and exercise in heart failure patients X-G. Sun. Fuwai
Hosp., Beijing.
A722 1132.13 Transient acidosis induces a preconditioning
chloride conductance that protects mouse nodose neurons
from NMDA-induced apoptosis Y. Lu, R. Wang, M.Z. Cicha,
M.W. Chapleau and F.M. Abboud. Univ. of Iowa and VA Med.
Ctr.
1133.HORMONES AND AUTOCOIDS IN THE KIDNEY
Poster
Poster
A710 1132.1 Intermittent hypoxia induces neuroplasticity
changes in the nucleus of the solitary tract J. Ciriello and J.M.
Moreau. Univ. of Western Ontario.
A711 1132.2 Effects of digitoxin treatment on reflex
cardiovascular control in rats with heart failure N.M. Fardin,
E.L. Antonio, J.A.S. Montemor, P.J.F. Tucci and R.R.
Campos. Fed. Univ. of São Paulo.
A712 1132.3 Fear-induced bradycardia is abnormal in rats
with heart failure S. Koba, I. Hisatome and T. Watanabe.
Tottori Univ. Fac. of Med. and Tottori Univ. Grad. Sch. of Med.
Sci., Japan.
A713 1132.4 Heart failure alters skeletal muscle afferent
acid-sensing ion channel subunit composition D.D. Gibbons,
M. Gautam and C.J. Benson. Univ. of Iowa.
A714 1132.5 Femoral artery occlusion amplifies TRPA1
function in skeletal muscle sensory neurons J. Xing, J. Lu and
J. Li. Penn State Col. of Med.
A715 1132.6 The role of TNF-α in femoral artery occlusionaugmented autonomic responsiveness J. Lu, J. Xing and J.
Li. Penn State Col. of Med.
A716 1132.7 Device-guided slow deep breathing in essential
hypertension: is cardiac or sympathetic baroreflex sensitivity
altered? A. Shantsila, A.M. Adlan, G.Y. Lip, A.E. Pickering,
J.F.R. Paton and J.P. Fisher. Sch. of Sport, Exercise &
Rehab. Sci., Univ. of Birmingham, Univ. of Birmingham Ctr. of
Cardiovasc. Sci. and Sch. of Physiol. & Pharmacol., Univ. of
Bristol.
A723 1133.1 Structural characterization of mixed wt/mutant
aquaporin-2 tetramers using dual-colored fluorescent subunit
counting Y. Lussier, H. McGuire, A. El Tarazi, P. Bissonnette,
R. Blunck and D.G. Bichet. Univ. of Montreal and Sacred
Heart Hosp. of Montreal.
A724 1133.2 Functional recovery of AQP2 recessive
mutations through hetero-oligomerization with wild-type
counterpart A. El Tarazi, Y. Lussier, S. Da Cal, P. Bissonnette
and D.G. Bichet. Univ. of Montreal and Res. Ctr., Hosp. of
Sacred Heart, Montreal.
A725 1133.3 Acute leptin exposure alters renal proximal
tubule function in vitro via mTOR and AMPK D.H. Hryciw, J.F.
Briffa, E. Grinfeld and A.J. McAinch. Univ. of Melbourne and
Victoria Univ., Australia.
1134.OXIDATIVE STRESS AND THE KIDNEY
Poster
A726 1134.1 The proton channel HV1 is expressed in the
medullary thick ascending limb of the kidney C.A. Stilphen,
J. Sun, N.A. Lambert and P.M. O’Connor. Georgia Regents
Univ.
383
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PHYSIOLOGYTUESDAY
A727 1134.2 Disruption of cyclooxygenase type 2
exacerbates the progression of oxidative stress during
obstructive nephropathy L. Nilsson, K. Madsen, B.L. Jensen
and R. Norregaard. Aarhus Univ. and Univ. of Southern
Denmark.
A728 1134.3 Nox4 contribution to H2O2 but not in superoxide
production in response to increased tubular flow in the mTAL
of Dahl salt-sensitive rats N.N. Zheleznova, C. Yang and A.W.
Cowley. Med. Col. of Wisconsin.
A729 1134.4 Renal responses to intra-arterial infusion of a
peroxynitrite scavenging agent with or without angiotensin II
in anesthetized rats D.S. Majid and A. Castillo. Tulane Univ.
Sch. of Med.
A730 1134.5 Genetic regulation of glutathione concentrations
and redox balance in kidney Y. Zhou, D. Harrison, K. LoveMyers, Y. Chen, A. Grider, K. Wickwire and R. Pazdro. Univ.
of Georgia and The Jackson Lab.
A731 1134.6 Dopamine D1 and D5 receptors differentially
regulate paraoxonase 2 S. Yang, P. Yu, Y. Yang, P.A. Jose
and C-Y. Zeng. Univ. of Maryland Sch. of Med. and Third
Military Med. Univ.
A732 1134.7 Podocyte NLRP3 inflammasome activation
and glomerular injury by adipokine visfatin: in vitro and in
vivo evidence K.M. Boini, M.M. Xia, J.M. Abais and P-L. Li.
A733 1134.8 Protective effects of docosahexaenoic acid
metabolites against homocysteine-induced podocyte injury by
inhibition of NLRP3 inflammasomes J.M. Abais, M. Xia, K.M.
Boini and P-L. Li. Virginia Commonwealth Univ.
A734 1134.9 High salt diet increases glomerular ROS
formation through an ET-1/ETA dependent mechanism J.B.
Heimlich, J.M. Speed, P.M. O’Connor and D.M. Pollock.
A735 1134.10 Changes in mitochondrial metabolism and
morphology contribute to sepsis-associated acute kidney
injury J. Thomas, K. Ayoyama, N. Nourbakhsh and P. Singh.
UCSD.
A736 1134.11 Prenatal steroid exposure promotes expression
of renal injury indices in African American females T.M.
Gwathmey, M.C. Chappell, P.A. Nixon and L.K. Washburn.
Wake Forest Sch. of Med.
A737 1134.12 Tumor necrosis factor-α supression rescues
glutathione peroxidase activity in kidney of insulin resistant rats
M. Carter, A. Lee, R. Rodriguez, M. Thorwald, R. Ortiz and
A. Nishiyama. Univ. of California, Merced and Kagawa Univ.
Med. Sch., Japan.
A738 1134.13 Time-dependent serum, urinary and tissue
biomarker responses to renal ischemia/reperfusion injury in
rats T.L. Richards, C.B. Glascock, T.R. Horn, K. McFarland
and C.F. Plato. Plato BioPharma Inc., Westminster, CO.
1135.SEX DIFFERENCES IN RENAL FUNCTION AND
DISEASE
Poster
A739 1135.1 Female mice retain more sodium than male
mice but maintain lower blood pressure during 30 days on a
high salt diet A. Rouch, L. Kudo, L. Fan, H. Hammami, M.
Nadeem and A. Chatzigiannidis. Oklahoma State Univ. Ctr.
for Hlth. Sci.
384
A740 1135.2 Effects of 17β-estradiol replacement in a model
of renal ischemia in the ovariectomized female apolipoprotein
E knockout mouse L. Li, H. Ji, C. Holloway, K. Sandberg and
C. Ecelbarger. Georgetown Univ.
A741 1135.3 Increase in renal proximal tubule GLUT5 and
ketohexokinase in male mice, but not female mice, in response
to high-fructose feeding may contribute to sex differences
in renal responses N. Sharma, L. Li and C. Ecelbarger.
Georgetown Univ.
1136.THE KIDNEY IN HYPERTENSION
Poster
A742 1136.1 PDGF receptor antagonism prevents the
increase in kidney ANG II levels in Cyp1a1-Ren2 transgenic
rats with ANG II-dependent malignant hypertension D.A.
Thompson, D.M. Seth, P.D. Davis and K.D. Mitchell. Tulane
Univ.
A743 1136.2 The role of activation of chemokine receptor
2 in TRPV1-mediated renal protection during salt-sensitive
hypertension Y. Wang, M. Zhu, W. Liu, X. Wang, L. Cui, S.
Shen, H. Xu and D. Wang. Henan Univ. of Traditional Chinese
Med. and Michigan State Univ.
A744 1136.3 Disruption of the WNK/SPAK pathway
attenuates angiotensin II, but enhances aldosterone-induced
hypertension L.G. Cervantes-Perez, M. Castañeda-Bueno,
N. Vázquez, I. Arroyo, N.A. Bobadilla, D. Alessi and G.
Gamba. Inst. of Biomed. Res., UNAM, Natl. Inst. of Cardiol.
Ignacio Chavez, Salvador Zubirán Natl. Inst. of Hlth. Sci. and
Nutr., Mexico City and Dundee Univ.
A745 1136.4 Decreased renal protein expression of
adrenomedullin and RAMP2 is associated with impaired
pressure-natriuresis in human GRK4γ 142V transgenic mice
D. Zhou, J.E. Jones, L. Asico, P.A. Jose and X. Wang. Univ.
of Maryland Med. Ctr. and Huazhong Agr. Univ., China.
A746 1136.5 Salt-inducible kinase 1 knockout mice show a
salt-retaining phenotype and salt-sensitive hypertension M.J.
Pinho, N. Pires, B. Igreja, L. Brion, A.M. Bertorello and P.
Soares-da-Silva. Dept. of Pharmacol. and Therapeut., Porto,
Portugal, BIAL, Porto and Karolinska Inst., Karolinska Univ.
Hosp.-Solna, Stockholm.
A747 1136.6 A novel mouse model for determining the role
of FKBP12 and calcineurin inhibition in tacrolimus-mediated
hypertension and hyperkalemia R. Lazelle, N. Meermeier,
C-L. Yang and D. Ellison. Oregon Hlth. & Sci. Univ.
A748 1136.7 Nephron-specific disruption of Cullin3 causes
salt-sensitive hypotension J.A. McCormick, A.S. Terker, B.
McCully, N. Meermeier, B. Yarbrough, H.J. Park, C-l. Yang,
J.D. Singer and D.H. Ellison. Oregon Hlth. & Sci. Univ. and
Portland State Univ.
A749 1136.8 AT2 receptor protects high sodium-induced
decrease in ACE2/Mas receptor expression and increase in
blood pressure in obese rats Q. Ali and T. Hussain. Univ. of
Houston.
A750 1136.9 Interaction of PPARα, CD36 and Th17 in
angiotensin II-induced hypertension A.O. Alatawi and A.
Oyekan. Texas Southern Univ.
TUESDAYPHYSIOLOGY
A751 1136.10 T cell-dependent hypertension is attenuated
in female mice during angiotensin II infusion D. Pollow, M.J.
Romero-Aleshire, J. Uhrlaub, J. Nikolich-Zugich, M. Hay
and H.L. Brooks. Univ. of Arizona.
A752 1136.11 Chronic infusion of angiotensin II changed
renal hemodynamic and function F.A.M. Casare and M.
Oliveira-Souza. Univ. of São Paulo.
A753 1136.12 The endoplasmic reticulum stress inhibitor,
4-phenylbutyrate, attenuates chronic kidney disease induced
by a model of cardiorenal syndrome R. Carlisle, K. Ask and
J. Dickhout. McMaster Univ. and St Joseph’s Healthcare
Hamilton, Canada.
A754 1136.13 High salt intake aggravates aortic dysfunction
in rats with adenine-induced chronic renal failure L. Nguy, H.
Nilsson and G. Guron. Univ. of Gothenburg.
A755 1136.14 Impact of uninephrectomy on body L-arginine
homeostasis and blood pressure control S. Pillai, R. Fingerhut
and F. Verrey. Univ. of Zürich and Children’s Hosp., Zurich.
A756 1136.15 Mutation of SH2B3 attenuates Dahl SS
hypertension via inflammatory signaling N. Rudemiller, H.
Lund, J. Priestley, A. Geurts and D.L. Mattson. Med. Col. of
Wisconsin.
A757 1136.16 Spontaneous essential hypertension in the
non-human primate Chlorocebus aethiops sabaeus, the
African green monkey M.K. Rhoads, A. Beierschmitt, D.
Huggins, J.A. Collett and J.L. Osborn. Univ. of Kentucky and
Behavioural Sci. Fndn., Saint Kitts and Nevis.
A758 1136.17 The effect of attenuating age-related increases
in blood pressure in male and female spontaneously
hypertensive rats on the kidney B. Li, A. Tipton and J.
Sullivan. Univ. of California, Merced and Georgia Regents
Univ.
A759 1136.18 The
glucagon-like
peptide-1
receptor
antagonist exendin-9 elevates blood pressure and worsens
renal function in SHR G.C. Aragao, M.H. Shimizu, A.P. Davel,
A.C. Seguro, A.A. McDonough and A.C. Girardi. Univ. of São
Paulo, State Univ. of Campinas, Brazil and Univ. of Southern
California.
A760 1136.19 Regulation of chromogranin A by hsa-miR-107
in hypertension and nephropathy S.M. Vaingankar, S.A. Mir,
K. Zhang, C.M. Hightower, J.P. Miramontes-Gonzalez and
D.T. O’Connor. UCSD.
A761 1136.20 Parallel changes in the urinary excretion of
ANG II and angiotensinogen and kidney ANG II levels in slowly
progressive ANG II-dependent hypertension D. Sigmon, D.M.
Seth, A. Sato, P.D. Davis, L.G. Navar and K.D. Mitchell.
Tulane Univ.
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1137.WATER AND UREA TRANSPORT IN THE
KIDNEY
Poster
A762 1137.1 The effects of altered extracellular pH on
dDAVP-induced phosphorylation (serine 256) and intracellular
trafficking of AQP2 H-J. Choi and T-H. Kwon. Sch. of Med.,
Kyungpook Natl. Univ., South Korea.
A763 1137.2 Increase in collecting duct basal:apical AQP2
protein expression ratio with increasing depth along the
corticopapillary axis positively correlates with maximum urine
concentrating capacity in the kangaroo rat and Sprague-Dawley
rat M. Espineira and T.L. Pannabecker. Univ. of Arizona.
A764 1137.3 Estrogen increases expression of aquaporin-2
protein in the inner medullary collecting duct D.L. Irsik, K.A.
Hyndman, E.S. Marks and E.I. Boesen. Univ. of Nebraska
Med. Ctr. and Georgia Regents Univ.
A765 1137.4 Quantitative proteomics of collecting duct cells
in bilateral ureteral obstruction-induced nephrogenic diabetes
insipidus S. Khositseth, P. Somparn, K. Charngkaew,
P. Uawithya, S-h. Chen and T. Pisitkun. Fac. of Med.,
Thammasat Univ., Fac. of Med., Chulalongkorn Univ., Fac.
of Med., Siriraj Hosp., Mahidol Univ., Thailand, Fac. of Med.,
Siriraj Hosp., Mahidol Univ., Thailand and Natl. Cheng Kung
Univ., Taiwan.
A766 1137.5 Aquaporin-2 interactome in rat inner medullary
collecting duct C-L. Chou, D. Hageman and M. Knepper.
NHLBI, NIH.
A767 1137.6 Identification
of
vasopressin-responsive
miRNAs and AQP2-targeting miRNAs in kidney collecting
duct cells J-E. Kim, H.J. Jung, H-J. Choi, J-S. Lim and T-H.
Kwon. Sch. of Med., Kyungpook Natl. Univ., South Korea.
A768 1137.7 Increased expression of sodium transport
proteins and Na, K-ATPase activity in the outer medulla of
kangaroo rat is related to its greater urine concentrating ability
compared to Sprague-Dawley rat M.Y. Aw, K.K. Evans and
T.L. Pannabecker. Univ. of Arizona.
A769 1137.8 Impacts of UT-A2 inhibition on urine
composition: a mathematical model R. Moss and A. Layton.
Duke Univ.
A770 1137.9 A mathematical model of rat proximal tubule
and loop of Henle A.M. Weinstein. Weill Cornell Med. Col.
A771 1137.10 Purinergic signaling is enhanced in the
absence of UT-A1 and UT-A3 R.T. Rogers, N.J. Himmel, S.K.
Redd and M.A. Blount. Emory Univ.
A772 1137.11 Identification of protein kinases that
phosphorylate the urea channel protein UT-A1 G. Hwang, C-L.
Chou, J. Hoffert and M. Knepper. NHLBI, NIH.
POSTER PRESENTERS:
UPLOAD YOUR POSTER
Where: E-Poster Counter, Lobby D
Deadline: Wed., April 30, 3:00 PM
Uploaded posters will be available online to all registered attendees
following the meeting at www. experimentalbiology.org
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