PDF - Archives of Iranian Medicine
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PDF - Archives of Iranian Medicine
In the Name of God the Compassionate the Merciful Archives of Iranian Medicine A Monthly Peer-Reviewed Medical Journal Founded in 1998 by the Academy of Medical Sciences of the I.R. Iran ISSN: Print 1029-2977, Online 1735-3947 Chairman: Iraj Fazel MD FACS Editor-in-Chief: Reza Malekzadeh MD Chairman of the Editorial Board: Karim Vessal MD Associate Editors and Editorial Board Shahin Akhondzadeh PhD Mohammad-Hossein Azizi MD Moslem Bahadori MD Hasan Esfandbod MD Arash Etemadi MD PhD Hasan Farsam, PhD Farshad Farzadfar MD, PhD Sadegh Massarrat MD Hossein Najmabadi PhD Siavosh Nasseri-Moghaddam MD Touraj Nayernouri MD Siavoush Sehhat MD FACS Ismail Yazdi DMD Mohammad-Reza Zarrindast PhD Editorial Office: P.O.Box: 19395-4655, Tehran, Iran Web: http://www.aimjournal.ir Tel: +98-218-864-5492 Fax: +98-2188656198 E-mail: aim@ams.ac.ir ; arch.iran.med@gmail.com Online Submission: http://www.aimjournal.ir:55/UI/ General/frmMainJournal.aspx Archives of Iranian Medicine is indexed in PubMed/ MEDLINE, ISI Web of Science, EMBASE/Excerpta Medica, SCOPUS, CINAHL, PASCAL, CSA, SID, and ISC. Statements printed in this journal, although believed to be reliable and accurate, are those of the authors and no liability can be accepted by the Academy and Editorial Board for errors of commission or omission incurred in the published material. Any reproduction or use of contents of the journal is permitted only if the source is properly cited. Board of Consultants Y. Aghighi MD A. Ahmed MD (USA) M. Akbarian MD J. P. Allain MD PhD (England) S. Asfar MD FACS (Kuwait) F. Azizi MD S. Bahram MD PhD (France) M. Balali-Mood MD B. Bastani MD (USA) H. E. Blum MD (Germany) S.H. Borghei MD B. Boroumand MD Y. Dowlati MD G. H. Edrissian Pharm D B. Eghtesad MD (USA) A. Emadi MD PhD (USA) H. D. Fahimi PhD (Germany) A. Fazel PhD A. Gasparyan MD PhD (Armenia) N. Ghahramani MD (USA) R. Gharib MD R. Ghohestani MD PhD (USA) B. Guyuron MD FACS (USA) M.A.Haberal MD FACS(Turkey) F. Habibzadeh MD M. Haeryfar PhD (Canada) M. Haghshenas MD F. Ismail-Beigi MD (USA) B. Jahangiri MD K. Kalantarzadeh MD (USA) N. Kamalian MD A. Khaleghnejad MD K. Khazaie PhD (USA) S. Koochekpour MD PhD H. Malekafzali MD PhD A. Malekhosseini MD A. Marandi MD S. Masood MD (USA) M. Matin MD V. Mehrabi MD F. Moattar PhD K. Mohammad PhD F. Motamedi PhD A. Nadim MD PhD B. Nikbin PhD M. Nooraie PhD N. Parsa MD PhD (USA) D. Paydarfar MD (USA) G. Pourmand MD S. Rad MD B. Z. Radpay MD F. Rahimi MD H. Rezvan PhD M. H. Sanati PhD M. R. Sedaghatian MD FAAP (UAE) F. Saidi MD H. Sajjadi MD (USA) S. Shariat MD F. Shokri PhD M. Sotoodeh MD E. Sotoodeh-Maram PhD M. Ugurlucan MD (Germany) A. Velayati MD M. Vessal PhD P. Vosugh MD M. Zali MD Editorial Statistical Advisors Asieh Golozar MD MPH Leila Ghalichi MD MPH Amir Kasaeian MSc Ahmad Reza Shamshiri MD MPH Mehdi Yaseri PhD Mohammad Ali Mansournia MD PhD Mohsen Vahedi MSc Editorial Staff Neda Bayat MSc (internal reviewer) Majid Boreiri MD (copy editor) Shokoufeh Borzabadi MSc (copy editor, executive director) Shima Ghoroghi MSc (copy editor) Siamak KarimkhanZand (design and layout) AmirEhsan Lashkari MSc (copy editor) Saeideh Riazi (public relation) Amir Sarbazi BA (web administrator) Sama Rezasoltani MSc (manuscript handling) Bahram Soleimani Amirabad (filling and posting publications) The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Chairman: Mohammad Taghi Joghataie Deputy Chair: Hamed Ekhtiari Basic Scientific Secretary: Mohammad Reza Zarrindast Clinical Scientific Secretary: Ali Farhoudian Executive Secretary: S.Javad Emamizadeh Poster Section Secretary: Reza Deneshmand Executive Director: Erfan Haeri Chairman Message Dear Friends, Dear Colleagues, On behalf of the organizing committee, it would be our great pleasure to invite all of you to participate in the 8th International Addiction Science Congress (ASC) in Tehran; September 10 - 12, 2014. Cellular and Molecular Research Center of Iran University of Medical Sciences and Substance Abuse and Dependence Research Center of University of Welfare and Rehabilitation as the main organizers of the conference invites all scientists and experts in this filed around the world especially regional countries to share their last findings and viewpoints in the areas. The program of the ASC 2014 conference with the theme of Multidimensional interventions in the addiction treatment and prevention offers an opportunity of learning in an environment with both theoretical and practical approach. Our scientific program covers the latest technologies and current status of the field, with applied learning opportunities. In addition to the scientific program, you will find opportunities to explore one of the most beautiful capitals of Islam, Tehran. I believe with your participation, this conference will be a fruitful collaboration environment. We are looking forward to see you in Tehran. Sincerely yours, Mohammad Taghi Joghataie Chairman Scientific Message Secretary Honorable Lecturers, Respectable Researchers, and Dear Colleagues, It would be an honor to invite you to attend the 8th congress on Addiction Sciences which will be held enjoying continuous efforts and supports of different specialist departments, societies, organizations, offices, as well as research centers. This congress is going to be held from 10 to 12 of September, 2014 in Tehran. Illicit drug use is one of the devastating problems worldwide, unfortunately we were endowed with little chance of handling the prevalence and reducing the harm. Lack of knowledge and biased opinions might be the cause for struggling with these complexities. Attending these congresses is one of the most efficient ways of updating the knowledge and bringing various scientific areas together. The 8th international congress on addiction sciences is intended to discuss multi-disciplinary topics including medical, psychological, social, communities, spiritual, epidemiological, legislative, and basic sciences related to addiction and addictive behaviors. Also, it is determined to provide the scientists and interested parties with the opportunity of sharing latest findings and discussing controversial topics. Observing lectures presented by eminent speakers, presenting outcomes of scientific researches by researchers, post graduates & under graduate students of Pre clinical, Para clinical & Clinical departments and holding variety of workshops are key plans of this congress. Presenting special awards for Young Scientists, awards for the best researches on prevention, awards for the most practical research and gifts for selected posters are the other routes of achieving the goals of this congress. We do warmly welcome our eminent international speakers who feel responsible and take pride in promoting constructive knowledge and improving skills of colleagues of the field worldwide. Also we express our deepest welcome to all participants, attending congress and presenting their esteemed countries. We are looking forward to meeting you in our congress, in Tehran, Iran. Ali Farhoudian Clinical Scientific Secretary Mohammadreza Zarrindast Basic Scientific Secretary Scientific Committee Dr .Mohammadreza Zarrindast Dr .Mohammadtaghi Joghataei Dr .Ali Farhoudian Dr .Hamed Ekhtiari Dr .Majid Hasanpour Dr .Majid Sadeghizadeh Dr .Reza Rostami Dr .Azarakhsh Mokri Dr .Mahmoudreza Hajighasem Dr .Mohammadhasan Farhadi Dr .Sarah Larney Dr .Saman Hoseinkhani Dr .Hedayatolallh Sahraei Dr .Saeid Sefatian Dr .Mohammad Farajollahi Dr .Mahdi Mahdizadeh Dr .Samideh Khouei Dr .Saeid Malihi-zakerini Dr .Fariborz Ahmadi Dr .Nasim Vosoughi Dr .Hadi Shirzad Dr .Amirhosein Yavari Dr .Ali rashidypour Dr .Mohammadtaghi Akbari Dr .Tahmineh Baheri Dr .Hamidreza Sarami Dr .Mohsen Roshanpajouh Dr .Ali Shahbazi Dr .Mehrdad Ehterami Dr .Farid Barati Dr .Gelareh Mostashari Dr .Fatemeh Moradi Dr .Ebrahim Rezaei-dogaheh Dr .Anahita Torkaman-butorabi Dr .Behrouz Dolatshahi Dr .Esmaeil Shahsavand Dr .Hassan Ashayeri Dr .Bijan Jahangiri Dr .Hamidreza Khoramkhorshid Dr .Hamidreza khankeh Dr .Mohammadreza Khodaei Ardakani Dr .Hamidreza Mostafavi Abdolmaleki Dr .Setareh Mohsenifar Dr .Sara Jafari Dr .Seyed Vahid Shariat Dr .Saeid Semnanian Dr .Abbas Motevalian Dr .Seyed Ali Hosseini Dr .Alireza Norouzi Dr .Aliakbar Nejatisafa Dr .Rabert Farnam Dr .Kamal Kharrazi Dr .Masoud Fallahi Khoshknab Dr .Mahmoud Tavakoli Dr .Abbas Haghparast Dr .Masoud Ghadipasha Dr .Javad Alaghbandrad Dr .Ali Yoonessi Dr .Majid Rezazadeh Dr .Fereshteh Motamedi Dr .Richard Rawson Dr .Mansureh Soleimani Dr .Masumeh Jorjani Mr .Mohammadreza Kooshesh Dr .Ali Samadi Kouchaksaraei Dr .Omid Massah Dr .Peymaneh Shirinbayan Dr .Minoo Mohraz Dr .Ahmad Hajebi Dr .Saeed Momtazi Dr .Mohammad Mehdi Gouya Dr .Masumeh Maarefvand Dr .Abbas Sedaghat Dr .Reza Daneshmand Dr .Hasan Rafiee Dr .Omid Yahyazadeh Dr .Asghar Dalvandi Dr .Mohammadreza Ghadirzadeh Dr .Hamid Jomepoor Dr .Shahindokht Molaverdi Dr .Ali Shafiee Mrs .Mahnaz Ahmadi Ms .Nojin Yasrebi Dr .Hasan Ziaeddini Dr .Fatemeh Ghazi Mirsaeed Dr .Naser Mansur Kiaie Executive Committee Erfan Haeri Marjan Derakhshandeh Yaser Ghahremani Marziyeh Karami Mohsen Esmaeili poor Maryam Goldoust Roghayeh Akhlaghi Masomeh bakhshayesh Tahereh Soleimanieh Naeini International Affairs Officer Tahereh Soleimanieh Naeini Organizers Cellular and Molecular Research Center ,Iran University of Medical Sciences Substance Abuse and Dependence Research Center ,University of Welfare and Rehabilitation Ministry of Health and Medical Education Welfare Organization Iran Drug Control Headquarter Iranian Neuroscience Society Colleagues Tehran Municipality Iran Psychology and Counseling Organization Narcotics Police cognitive sciences and technologies council UCLA Iranian National Center for Addiction Studies Regional Programme for Afghanistan and neighbours Countries Iranian Anatomical Sciences Association Institute of Cognitive Science Health Channel IRIB UNICEF Centre for Mental Health Research ,Institute of Psychiatry UNODC Iranian Legal Medicine Organization Iranian Psychiatric Association Vice President of Women›s Affairs and Family Eco Cultural Institute OR L A ORAL The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Survey on High-Risk Sexual Behaviors among Injecting Drug Users in Ahvaz Drop in Center(DIC) : 1392 Zohreh Abbasi1, Abbasi Z(MA)2, Davasaz Irani R(MPH)3, Barzkar A(MA)4, Mansouri S(BA)5 1. Department of Mental, Social Health and Addiction .Health Center of Khuzestan province,Ahvaz Jundishapour University of medical science 2. General Psychology 3. department of mental, social health and addiction .Health center of Khuzestan province,Ahvaz Jundishapour University of Medical science 4. Clinical Psychology_manager of DIC 5. General Psychology-Center of Local Mental Health Avaye Zendegi - Ahvaz Background and Aim Sexual risk behaviors in drug users are not uncommon, and they have been subject to considerable.the aim of this study was to survey risky sexual behaviors among Injecting drug users in Ahvaz Drop in Center. Methods This was an analytic-descriptive study. The study population consisted 138 Injecting drug users who had referred to Ahvaz Drop in Center. Data was gathered by Risky sexual Behavior questionnaire(RSBQ) .This was a researcher- made questionnaire that its validity was cheked by expert opinion and its reliability was measured through person’s Correlation(0.70). The data were analyzed using descriptive statistical methods, X2 and Logistic Regression by SPSS16. Results Findings indicated that 25% of Injecting drug users were infected with the HIV virus. Most addicts (%98) belonged to the group of men, (%85) Had a low education level, (%72) single (%75) were unemployed. Well as (%35) had a prison record, and (%55) had sex with multiple partners. The highest frequency in conjunction with the lack of interest in the use of condoms, belonged to the age group 24-20 years. A significant relationship was found between marital status and risk behavior(P≤0.05),but no significant relationship was found between other demographic characteristics and behaviors studied(P≥0.05). Results of regression analysis showed that the highest risk of HIV infection due to sexual risk behaviors was related to having sexually behaviors unconventional and sexual partners who are infected with HIV respectively. Conclusion Due to the prevalence of high-risk behavior among injecting drug users, Can greatly control the risks of addiction and transmission of infectious diseases such as AIDS to the community through increasing Drop in centers and proper training. Keywords Risky Sexual Behaviours, Drug User, Drop in Center, Ahvaz Comparing High Risk Sexual Behavior of Addicted Women Before and after Addiction Treatment Ebrahim Abbasi1, Mahmood Abbasi2, Ahmad Abbasi3 1. Expert at dchq 2. Expert at Legal Medicine Organization 3. Expert at Markazi Government, Arak, Iran Background and Aim Goal: in this research we compare the sexual behavior of addicted women before and after addiction treatment. Methods Method of research: this study is a quasi-experiment. For that, we choose 256 addicted woman according to research factors. We choose those who passed at least one month of treatment and their sexual function analyses before and after treatment. For taking information we use demographic questionnaire and deep interview Results Results there is a relationship between the kind of drug, and severity of using it and high risk sexual behavior in addicted women. In the other side there is a diverse relationship between persistence of treatment of addiction and desire to high risk behavior. More important desire to have sexual behavior in the beginning of treatment is more than the period of taking drugs Conclusion Discussion and Conclusion women before treatment of addiction, because of need to the drug, try to have sexual behavior that in this step they are to have any kind of sexual behavior, therefore after treatment the high risk sexual behavior will reduce, but because of not informing enough of treatment and increasing the libido, mostly they have sexual relation with others rather than their husband. After a period, the sexual desire will reduce, so having the harm reduction centers for women in cities with a psychologist or social worker in those centers, especially camps, with the goal of training women and informing them is necessary Keywords High Risk Sexual Behavior, Addiction Treatment, Drug Abuse Role of Mindfulness, Machiavelli’s, Resiliency in Addiction & Tendency to Substance Use Sadegh Khodamoradi1, Gholamreza Manshaee2, Atefeh Abbasi3 1. Student PhD, Psychology Group, Science and Research Branch Islamic Azad University of Tehran, Tehran, Iran 2. Psychology Group, Science and Research Branch Islamic Azad University of Esfehan, Esfehan, Iran 3. Student PhD, Psychology Group, Science and Research Branch Islamic Azad University of Tehran, Tehran, Iran Background and Aim Mindfulness starter conciseness, Machiavelli’s assert will damage, and resiliency is factor for resistance. article aim, assessment Role of Mindfulness, Machiavelli’s, resiliency in addiction & tendency to Substance use Methods This was a correlation descriptive study Results Weak Mindfulness, major Machiavelli’s, and good resiliency is effect in addiction & tendency to Substance use S2 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Conclusion Weak Mindfulness to cause, behavior management to transfer to Unconscious systems that follower pleasure. Machiavelli’s Is likely to cause any type of violence. and resiliency Raises resistance to damage. Keywords Mindfulness, Machiavelli’s , Resistance, Addiction, Tendency to Substance Use Distribution of Mental Disorders in HIV-positive Patients in Kermanshah Jalal Shakri1, Nasrin Abdoli2, Vahid Farina3 1. Psychiatrist and Associate Medical Sciences, Kermanshah 2. PhD Student at University of Mashhad Imam Reza 3. PhD Student at University of Mashhad Imam Reza Background and Aim Introduction assaults taking the world by virus devastating HIV from focusing and global problems in the late twentieth and Avaylb The provider-first century poses Rvdkvshsh researchers in understanding better the nature and effects of HIV on the lives of patients and those around them by providing referred to the Counseling Center, Health Center, Kermanshah province was HIV-positive patients. Methods Materials and Methods In this study of HIV-positive patients who were at the center of the case. 132 people older than 15 years of sampling the “available” were selected and evaluated in a study. This study was conducted in two stages. symptoms based on DSM-IV diagnostic criteria were interviewed. Results Results Among psychiatric disorders, disorders related to drug use in the 93/93 percent of people with mood disorders in the 18/43 percent Guantanamo and suspicion 7/32 of Impaired agitation in 93/18 cases studied, the most common abnormalities were found. The prevalence of other Disorders in this study include: disorders somatoform a 36/11 percent, schizophrenia and other psychotic disorders, with 60/10% of cases, sleep disorders in the 09/9% of cases, impaired impulse control in 03/3%, adjustment disorder in 27/2 percent of sexual dysfunction in 75/0 of cases of bereavement in 75/0 of the cases examined among axis II personality disorders in 24/74 per cent or more. In this study, 90 /.% Of men and 08 /. .78/53 Per cent of the unemployed were women and most were in the age range 130-18 96/46 per cent of respondents fills. 78/78 had a diploma or diploma below. Conclusion Conclusion Considering the high prevalence of HIV among drug abusers and psychiatric disorders, along with the identification and timely introduction of clinical psychiatry or psychology, and get advice when HIV can enhance the quality of life of these patients and the implementation of mental health, individual and family helped Keywords Psychiatric Disorders, Kermanshah, SRQ-24, DSM-IV, HIVPositive. Couses of Tendency Youth to Addiction from the Perspective Rasht PNU Students Maryam Abdollahi1, Soodabeh Afra2, Maryam Arabnejad3 1. PNU,Rasht,Iran 2. PNU,Rasht,Iran 3. PNU,Kerman,Iran Background and Aim Drug use as a social habit and unacceptable in all societies involved countless men and women, especially the young people . Studies in this field have showed that individual, social and family factors are effective in the tendency to use drugs. This study aimed to investigate the factors influencing trends in youth drug use from the perspective of students. Methods This descriptive - analytical study was conducted on 100 students of Rasht PNU. The tool of collecting data was questionnaire that was made by the researcher. In design and setting questionnaire, were used indicators such as the emotional atmosphere in the family, social relations, and some personal characteristics. Validity of the used test by retest obtained. 0/73. To achieve to the research objectives was used multiple regression method. Results This study showed that young people believe lack of healthy leisure (33/0), lack of employment and unemployment (30/0), location (24/0), education level (23/0 to be the most effective to tedency drug. Conclusion With Attention to the results obtained in this study, the most important indivisual, social, family factors in youth drug tendency from the perspective of the students are lack oft healthy leisure, lack of employment and unemployment, inappropriate living place and education that likely can be prevented from spreading this problem by teaching technical and professional skills, spread healthy cultural centers with diverse cultural and henry program Keywords Causes of Tedency, Addiction, Youth Study of the Relationship Between Adjustment and Self-Esteem in Addict and Non-addict Youths of Esfahan Zahra Adham1, Azam Shamohammadi2 1. M.A. in General Psychology,Department of Justice Crime Prevention Isfahan 2. M.A. in General Psychology, Esfahan Public Education Background and Aim The purpose of the present study has been evaluation and comparison of the amount of adjustment and self-esteem in addict and non-addict youths. Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S3 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Methods Accordingly, 60 substance-addicted youths and 60 non-addict youths of 20-35 years old were selected through stratified random sampling. Bell’s adjustment questionnaire which includes 160 questions and evaluates 5 sub-criteria was used in this research along with Coopersmith’s self-esteem test which consists of 58 questions and 4 sub-criteria. Data analysis was performed at the level of inferential statistics by t-test and SPSS software. Results Ultimate analysis of the data indicated that there is a significant difference in adjustment at home, health adjustment, socialemotional adjustment between addicts and non-addicts (p< 0.05). Moreover, there is a significant difference between self-esteem of addict and non-addict youths (p< 0.05). Conclusion Hence, it can be claimed that addict youths have lower levels of adjustment and self-esteem than non-addict youths. Keywords Adjustment, Self-Esteem, Addict and Non-Addict. Predictive Factors of Recurrence Among patients Treated with Methadone Maintenance Treatment Referred to Addiction Centers in Hamadan Based on Health Belief Model Ali Afsar1, Seyed Mohammad Mehdi Hazavei 2, Saeid Bashirian 3, Jalal Poorolajal4, Elahe Vatannavaz5 1. MSc of Health Education, Department of Public Health, School of Health, Hamadan University of Medical Sciences, Hamadan, Iran 2. Department of public health, school of health, hamadan university of Medical Sciences, Hamadan, Iran 3. Department of public health, school of health, hamadan university of Medical Sciences, Hamadan, Iran 4. Department of Epidemiology School of Health, Hamadan University of Medical Sciences, Hamadan, Iran 5. MSc of Health Education, Department of Public Health, School of Health, Kurdestan University of Medical Sciences, kurdestan, Iran Background and Aim One of the major challenges in current methadone maintenance treatment is retention rates in the treatment and prevention of addiction recurrence. The aim of this study was determine the factors that influence addiction recurrence among patients undergoing methadone maintenance treatment , based on Health Belief Model, in Hamadan addiction treatment centers . Methods This cross-sectional study conducted in the spring and summer of 2013 on 384 patients treated with methadone in addiction treatment centers in the Hamadan city. Stratified proportional sampling was conducted. Data were collected via questionnaire based on the Health Belief Model constructs and demographic variables, the questionnaires were completed by interviews and self-report. Data analysis was performed using software SPSS (version 19), and using regression analysis and chi-square test. percent. Temptation, friends’ pressure, depression and methadone low dose were the main reasons for recurrence. Regression analysis indicated constructs of perceived susceptibility, perceived benefits and self efficacy were stronger predictors of recurrence. Conclusion According to the results, it seems Health Belief Model can be used for recurrence prevention intervention programs. Keywords Recurrence, Methadone Maintenance Treatment, Health Belief Model Comparing Direct, Network Scale up, and Proxy Respondent Methods in Estimating Risky Behaviors and Substance Use among Collegians Mahdi Afshari1, Khodadad Sheikhzadeh2, Mohammad Reza Baneshi3, Ali Akbar Haghdoost4 1. Department of Public Health, School of Public Health, Zabol University of Medical Sciences, Zabol, Iran 2. Regional Knowledge Hub, and WHO Collaborating Centre for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran 3. Research Center for Modeling in Health, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran 4. Research Center for Modeling in Health, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran Background and Aim Various methods of estimating the size of hidden populations are prone to different degrees of information biases. This study for the first time, aimed to assess such biases. Methods We estimated the prevalence of risky behaviors such as substance use using direct, modified Network Scale-Up (NSU) and Proxy Respondent Method (PRM) among college students. Results The network sizes of the male and female students were 25.8 and 29.5. We found alcohol use was the most prevalent risky behavior among males (PRM: 18.12%, NSU: 8.68%, Direct: 13.4%) and the extra-marital sex was the most prevalent one among females (PRM: 3.47%, NSU: 0.95%, Direct: 1.4%). Based on PRM, Injecting Drug Use (IDU) was the least prevalent behavior among college students. Conclusion We concluded that direct and NSU methods might underestimate the prevalence of substance use and risky behaviors. Keywords Risky Behaviors, Network Scale up, Proxy Respondent The Effect of School- Based Interventions on Middle School Students’ Life Skills in order to Preventing Drug Abuse Results The recurrence rate in patients treated with methadone was 48/2 S4 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 Parvaneh Aghajari1, Sousan Valizadeh2, Farhad Taremian 3, Mahnaz Jabraili 4, Mohammad Hashtrudizadeh5 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall 1. Department of Pediatric Nursing, Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran 2. Department of Pediatric Nursing, Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran 3. Department of Psychiatry, Zanjan University of Medical Sciences, Zanjan, Iran 4. Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran 5. Medical Sciences Faculty, Maragheh, Iran Background and Aim Adolescence is a critical period in life and the important behavioral patterns such as smoking, alcohol and drug use, that affects whole of the life, is formed in this stage. One of the school-based preventive interventions is Life Skills Training (LST). This study assesses the effect of school-based interventions on middle School students’ life skills in order to preventing drug abuse. Methods This study is a pre and post test quasi- experimental study with control group that 417 students participated in 2 and 3 grades of Maragheh’s middle schools. Eight girls’ and boys’ schools were selected randomly through the schools list of Education office and after pre-test, were divided in 2 groups. In the case group, we performed the LST program in the 7 session, and then tested both of the case and control groups. The questionary included the demographic questions, PSI, HSS, CATS, and Dr. Botvin’s healthy behavior scales. Then we analyzed data by SPSS ver. 15 software by t-test and χ2. Results In post- test, mean scores of decision making and problem solving skill (P<0.01), self- esteem (P<0.05), and resistance skill (P<0.01) had a significantly increasing and tendency to drug abuse (P<0.05) had decreased significantly in case group. Conclusion LST program in case group was affective on students’ life skills, and then it was offered as a protective factor in preventing of schools drug abuse. In this prospective study, 210 drug addicts who referred to the methadone maintenance Therapy centers during the first month in 1392 (2013), were sampled purposefully. The subjects were studied using the author-build questionnaire of data on demo chart and a short list of the nature and disposition, and followed for 6 months. Data were analyzed thorough independent T-test Results The results showed that patients who had a relapse obtained the higher scores in novelty seeking and harm avoiding dimensions, and the lower scores in self-directing and coordination in comparison with the non-recurrence group. There was no difference between the two groups in perseverance and reward-seeking personality traits Conclusion According to the Cloninger personality trait model, high novelty seeking and harm avoiding, and low self-directing and coordination present the valuable information about the effectiveness of personality traits in relapse which may highly be influential in both Therapy and prevention of abusers’ relapses. Keywords Relapse, Personality Traits, Methadone Maintenance Therapy The Relationship between Domestic Violence and Partner Addiction in Women Attending Health centers - Health and Family Courts city of Rasht in 1392. Mahbobbeh Ahmadi1, Mona Rahnavardi2, Mehrzad Kiani3, Asma Porhoseyn Gholi 4 1. Shahid Beheshti University Of Medical Science,Tehran,Iran 2. Shahid Beheshti University Of Medical Science,Tehran,Iran 3. Shahid Beheshti University Of Medical Science,Tehran,Iran 4. Shahid Beheshti University Of Medical Science,Tehran,Iran Background and Aim Keywords School Health Services, Early Intervention (Education), Students, Substance-Related Disorders, Prevention & Control Effective Personality Traits on the Relapse for Drugs Abuse in Opioid Dependents under Methadone Maintenance Therapy Hossein Aghazadeh vazifekhah1, Mehdi Sedghi2, Amir Ahmadi3, Babak mohammadi4 1. Master of Clinical Psychology, Islamic Azad University of East Azarbayjan Science and Research Branch. 2. Master of Clinical Psychology, Islamic Azad University of East Azarbayjan Science and Research Branch. Young Researchers and Elite Club, Tabriz 3. Master of Clinical Psychology, Islamic Azad University of East Azarbayjan Science and Research Branch. Young Researchers And Elite Club, Tabriz 4. Master of Clinical Psychology, Islamic Azad University of Ardabil Science and Research Branch. Young Researchers And Elite Club, Tabriz Background and Aim Methods Domestic violence are one of the most important contributors to the global burden of disease among women and girls, Evidence suggests that drug and alcohol addiction and abuse is a important personal factors for violence against women In the family. The purpose of this study was to determine the relationship between domestic violence and partner substance abuse in women Methods This study is a case - control study , population consisted of 110 (55 people with violence and 55 without violence) qualified women referred to health centers and family courts are the city of Rasht. Sampling method was available or easy. We use domestic violence questionnaire and demographic questionnaire for this study. Independent t, chi - square, Mann-Whitney, and descriptive statistics were used to analyze the data. Results The present study investigated influential personality traits on the relapse for drugs abuse in opioid dependent patients under the Therapy with methadone. The mean age in the group without violence 32/69 ± 7/65 years. Highest scores related to psychological violence, with an average 44/13. Opium consumption (P = 0/03), heroin (P = 0/002) was significantly higher in women with violence Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S5 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Conclusion According to high prevalence of domestic violence in this study and understanding substance abuse as a major risk factor for violence on women’s. Prevention programs should be compiled in mental health policy and have the resources will be assigned to prevent violence against women and its adverse consequences. Keywords Domestic Violence ,Opium Consumption ,Heroin,Addictation Addiction Documenting in the Medical Records Golchehreh Ahmadi1, Sima Ajami2, Sakineh Saghaeiannejad-Isfahani3, Masoud Etemadifar4 1. Health Information Technology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran 2. Health Management and Economics Research Center, Isfahan University of Medical Sciences, Isfahan, Iran 3. Social Determinant of Health Research Center, Isfahan University of Medical Sciences, Isfahan, Iran 4. Isfahan Research Committee on Multiple Sclerosis, Isfahan, Iran Background and Aim Medical records (manual or computerized) are a healthcare information repository and must be adequately described all steps of patient care and disease management. The first step to standardize data collection to facilitate and expedite sharing and comparing data among different centers is determining standard data elements. The aim of this study was to determine addiction data elements in the Multiple Sclerosis (MS) medical records. Methods This research was an applied one and an exploratory study which was done in Isfahan in 2012, in four phases: 1) identifying MS information resources in Iran and other countries; 2) extracting, summarizing and categorizing addiction data elements; 3) proposing addiction data elements in MS medical records; and 4) evaluating of data elements by Delphi technique. The research population in the first three phases included: MS specialists and information management systems planners, MS specialty clinics, neurology offices, university and research centers in Isfahan city and the Isfahan MS Society, websites about MS, MS treatment and research centers in other countries; and in the last phase included: neurologists in Iran. Finding data was analyzed by descriptive statistics indexes, just relative and absolute frequencies. Delphi technique was continued until achieving consensus for every data element. Results After identifying 17 MS information resources at the world, 15 addiction data elements was extracted and classified in two categories; Clinical and Socioeconomic. In the first round of the Delphi technique, 15 Neurologists did not get to 75% consensus for any of considered data elements. In the second round, 12 of previous participants deleted 6 cases out of 15 cases. Finally, addiction data elements for MS medical records were determined. Conclusion The MS data collection is the first step in MS information management. Nowadays, demands for applying data collection standards are growing up. The key point in determining the data elements is obtaining consensus and standardization of data that must be collected. Comparative studies will be possible by standardization and providing unique definitions. According to specialists’ consensus on necessity of addiction data elements in MS medical records, using these data elements is recommended as a basis for collecting data on MS and other Chronic Disease and conditions in Iran. Keywords Medical Records, Data Elements, Multiple Sclerosis, Smoking, Substance Abuse, Alcohol, Addiction. The Influence of Hope Treatment on Reduction of the Depression Amount and Prevention from its Reappearance among Treated Women who Depend on Drugs Amir Ahmadi1, Babak Mohammadi2, Mahdi Zare3, Hafez Atapour4 1. Master of Clinical Psychology, Islamic Azad University of East Azarbayjan Science and Research Branch. Young Researchers And Elite Club, Tabriz 2. Master of Clinical Psychology, Islamic Azad University of Ardabil Science and Research Branch. Young Researchers And Elite Club, Tabriz 3. Master of Clinical Psychology, Islamic Azad University of East Azarbayjan Science and Research Branch. Young Researchers And Elite Club, Tabriz 4. Master of Clinical Psychology, Islamic Azad University of East Azarbayjan Science and Research Branch. Young Researchers And Elite Club, Tabriz Background and Aim The purpose of present study was to research the influence of hope treatment education on reduction of the depression amount and prevention from its reappearance among treated women who depend on drugs. Methods In a similar experiment plan, 30 distinguishing the disorder of opium misuse that had finished the period of poison removing and got 14 point or above of the depression marks in depression questionnaire, were accidently divided into experimental group (15) and witness group (15) by available sampling method, experimental group were educated with hope treatment in 10 sessions and witness group did not receive any treatment at this period. The researched experimented were evaluated by the scale of Snayder hope and Beck depression and Mourfin test before starting and finishing treatment and finishing 2-month exploring process. Z scale test and covarians analysis test were used to analyze the data from Chi-square test. Results Showed that the education of hope treatment can remarkably reduce the amount of depression target among addicted women. In addition to, the test results have showed the meaningful difference in the number of reappeared women by considering the group (experiment and witness). Conclusion In whole idea, the result of this study shows that the education of hope treatment is efficient in reduction of depression amount and prevention from its reappearance among treated women who depend on drugs. Keywords Hope Treatment, Depression, Dependence on Drugs, Prevention from Reappearance. S6 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Role of Abuse in Lapse, During Methadone Maintenance Treatment (MMT) Elaheh Ahounbar , Behrouz Dolatshahi , Ali Farhoudian 1. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 2. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran Clinical Psychology Dept., University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 3. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 1 2 3 Background and Aim The aims were to identify if histories of sexual, emotional and physical abuse are predictors of lapse in some of Tehran/Iran methadone maintenance treatment (MMT) clinics, and to compare the findings to other international settings. Methods We prospectively studied 120 patients admitted since November 2013 through 6 months to MMT clinics. Results Analyses included urinalysis results (for methadone, cocaine, opiates, benzodiazepines, THC, amphetamines) of each patient per month and after 6 months in treatment and patients’ frequency of reporting physical, emotional & sexual abuse. The 6 months lapsing rate was 45.4% opiate abuse and 64.7% Methamphetamine abuse during treatment. Conclusion Histories of sexual, emotional and physical abuse were actually factors predicting lapse in MMT. We conclude that our outcome results (high rate of lapse during 6 months MMT among patients with high physical, emotional & sexual abuse, justify the need of monitoring such patients in the MMT clinics in order to make treatment most effective to all those who need it. A protocol favoring extra supportive interventions as appropriate is recommended. Keywords Sexual, Emotional and Physical Abuse, Lapse, Methadone Maintanace Treatment Effectiveness of Mindfulness-Based Group Therapy in Reducing Symptoms of Depression and Increase the Self Efficacy of Drug-Dependent Patients Asqar Alizadeh1, Asghar Alizadeh2, Mohammadreza Hoseinpour3, Raana Sheikhzadeh soori4, Leila Hasanzadeh5, Masoumeh azmoodeh6, Mehdi Yaghouti7 1. Department of Clinical Psychology, College of Psychology, East Azarbaijan Sience and Research Branch, Islamic Azad University, Tabriz, Iran 2. Department of Clinical Psychology, College of Psychology, East Azarbaijan Sience and Research Branch, Islamic Azad University, Tabriz, Iran 3. Department of Clinical Psychology, College of Psychology, East Azarbaijan Sience and Research Branch, Islamic Azad University, Tabriz, Iran. 4. Department of Clinical Psychology, College of Psychology, Islamic Azad University, Ardebil, Iran. 5. College of Psychology, Payam Noor University, Tehran, Iran. 6. College of Psychology, Islamic Azad University, Tabriz, Iran. 7. Center for Addiction Treatment (Khane Amn Isfahlan). Background and Aim Addiction and associated disorders, it is one of the problems of human society that in recent years there are weak pillars and foundations of human society and large capital Spending for struggle costs, treatment and injuries. Therefore, the main objective of this research is effectiveness of mindfulness-based group therapy in reducing symptoms of depression and increase the self efficacy of drug-dependent patients. Methods The research is of the type semi-experimental with experimental and control groups, with follow-up (45 days). The sample size is 30 people. They was selected by methods available from refere patients to addiction clinic (khane amn isfahlan) in 1392 and they were randomly divided into treatment group (mindfulnessbased therapy) and control group. Experimental groups during the 12 sessions of 60 to 90 minutes was treated in the group and the control group received only methadone. All subjects before treatment, at the completion of the twelfth and final follow up, 45-day, completed short form of the Beck Depression Inventory (13 - BDI) and the self-efficacy questionnaire. Results The results of multivariate analysis of variance (MANOVA), comparing the difference between pre-test and post-test experimental and control groups were equal (F =75/68) , the F between the two groups in the post-test and follow-up depression were equal (F =4/12) and analysis results between pre-test and posttest in an increased level of self-efficacy and experimental groups were equal (F=104/53) and analysis of variance post-test and followed by increasing levels of self-efficacy in experimental and control groups were equal (F=./850). Conclusion Effectiveness of mindfulness-based group therapy in reducing symptoms of depression and increase the self efficacy of drugdependent patients is effective. Therefore, thoughts and feelings is performed without judgment and evaluation with the help of mental imagery. Keywords Mindfulness-Based Group Therapy, Addiction, Depression, Self-Efficacy Effectiveness of Group Therapy with NA Structure on the Internal and External Control Level and Psychological Well-Being of Self-Introducer Addicts to Addiction Rehabilitation Centers Masoumeh Allahi1, Bahman Akbari2, Farhad Asqari3, Behrooz Golchai4, Simin Moradoi Azad5 1. M.A in Clinical Psychology, Azad University Branch Tonekabone, Iran 2. PhD in Psychology, Azad University Science and Research Branch Guilan, Rasht. Iran 3. PhD in Psychology, Azad University Science and Research Branch Guilan, Rasht. Iran 4. Medical Student 5. M.A in Clinical Psychology, Azad University Science and Research Branch Guilan, Rasht. Iran Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S7 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Background and Aim NA (Narcotics Anonymous) meetings are trying to promote personal characteristics and behavioral changes of addicts for increasing their persistent quitting behavior after detoxification period. The purpose of this study is to evaluate efficacy of group therapy using NA structure on the level of internal and external control and psychological well-being of the self-introducer addicts to rehabilitation centers. Methods This experimental study with pre-and post-test design with a control group was conducted on 200 individuals in addiction rehabilitation centers in CHALUS. Among the study population,24 subjects with lower psychological well-being and source internal control were randomly selected and divided into two equal(12 subject) experimental and control groups. Next, group therapy based on NA was performed on experimental group once a week for 3 months and 12 sessions of 60 minutes. Results According to result of present study, group therapy with NA structure was highly effective in enhancing the wellbeing(F(1,22)=10.230,p=0.004) and changing control resources( F(1,22)=10.040,p=0.005) of the patients. Conclusion This study showed that group therapy with NA structure can enhance the internal and external control level and psychological well-being of the patients. Keywords Group therapy, Control of Resources, Well-Being Causes of Women’s Illicit Drug Addiction in Tehran: A Qualitative Study Leila Allahqoli1, Sepideh Hajian 2, Zhila Abeed Saeedi3, Nader Molavi 4 1. PhD Student of Reproductive Health, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran 2. PhD in Reproductive Health, Assistant Professor, Dept. of Midwifery and Reproductive Health, Faculty of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran 3. Assistant Professor, Dept. of Medical Surgical, Faculty of Nursing & Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran. 4. PhD Student of Addiction Studies, Kashan University of Medical Sciences, Kashan, Iran Background and Aim Due to biological, psychological and social issues, women are at a higher risk of illicit drug addiction than men. Drug addiction etiology in women is multi factorial. The purpose of this article is to determine the pivotal factors in women’s illicit drug addiction in Tehran. Methods Qualitative method was utilized. Two focus groups and sixteen semi-structured in-depth interviews were conducted with drugaddicted women, 15-45 years old, at shelters and drop-in-centers in Tehran. Participants were selected by purposeful sampling. All interviews were recorded and typed word for word. Data was analyzed using content analysis approach. Results Participants’ mean age was 30; all of the participants had at least primary school education. Majority of the participants were divorced. Two of the participants were injection drug users infected with hepatitis B; three of them were infected with HIV. Two-thirds of the participants were homeless and more than two-thirds were sex workers. Findings of this study can be grouped in two main categories: extra-personal and personal factors. Extra- personal factors include family and social factors. Personal factors include personality characteristics, demographics, non-favorable healthy background, previous high risk experience, and factors related to individual’s perceptions. Conclusion The present study demonstrated that the main influencing factors in women’s drug addiction are extra-personal factors. Therefore, to protect vulnerable women from drug addiction, a realistic prevention planning is needed to provide support for those more susceptible to harm, and to provide them with education and employment, as well as guidance for them to become self-sufficient and independent. This plan will also help to recognize the talents and capabilities of these vulnerable women and guide them to better utilize these capabilities. Keywords Drug- Addicted, Women, Causes, Qualitative Research. Women’s sexual behavior and illicit drug Addiction in Tehran: A Qualitative Study Leila Allahqoli1, Sepideh Hajian 2, Zhila Abeed Saeedi3, Nader Molavi 4 1. PhD Student of Reproductive Health, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran 2. PhD in Reproductive Health, Assistant Professor, Dept. of Midwifery and Reproductive Health, Faculty of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran 3. Assistant Professor, Dept. of Medical Surgical, Faculty of Nursing & Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Ira 4. PhD Student of Addiction Studies, Kashan University of Medical Sciences, Kashan, Iran Background and Aim Changes in illicit drug-addicted women’s sexual behavior have changed STIs dissemination pattern and have exposed them to a higher risk of HIV infection. The purpose of this article is to determine sexual behavior in women’s illicit drug addiction in Tehran. Methods Qualitative method was utilized to determine sexual behavior among drug-addicted women. Between February and May 2013 two focus groups and sixteen semi-structured in-depth interviews were conducted with drug-addicted women, 15-45 years old, at shelters and drop-in-centers in Tehran, Iran. All interviews were recorded and typed word for word. Data was analyzed using content analysis approach. Results The age range of women in this sample was 17 to 43, with majority being in their Thirties. More than half of them had primary or middle school education; slightly more than three quarters, 14 S8 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall (77%), were divorced. Two of the drug abusers were injection drug users infected with hepatitis B; three of them were infected with HIV. Two-thirds of the participants were homeless and more than two-thirds were sex workers. All participants were sexually active, and most of them, 88%, had unprotected sexual relationships. The reasons for having unprotected sexual relationship were financial need, receiving emotional support, disruption in pleasure, and misconception about condom use. For majority of the participants financial need was the most important reason for having sexual relationships. Conclusion Most women are not aware, or have incorrect understanding, of the dangers of having risky sexual behaviors. The study results emphasizes on the need for affiliated organizations to conduct preventative and harm-reduction programs continuously and accurately, to offer effective training to exposed groups, and to provide expert consultation. Keywords Sexual Behaviors, Drug-Addicted, Women, Iran Investigate the Causes and Trends of Industrial Drug Abuse in Arak and Provincial Media in Reducing the Damage Abolfazl Amirian1, khadijeh Esmaeili zadeh2, Nafiseh Ahmadi3 1. Azad Islamic University of Arak 2. MA in Counseling- Azad Islamic university of Oloum Taghighat Markazi 3. Education Organization of Qom Province Background and Aim The present study aimed at investigating the causes of industrial drug abuse process and the role of media in reducing this damage in Arak. Methods This research was taken place through Descriptive approach on 394 individuals, including 221 men and 173 women younger than 35 years of age in drug addiction treatment centers. The study assessment tool was a five dimensional researcher-made questionnaire to which all the participants responded. Results Findings shows that, thrill seeking, in both sexes, illness experiencing factors, love failure, heavy and long-term burden, being fond of fashion include the most important individual factors associated with the tendency to addiction. Among the family factors, having the addicted family members for both sexes, unresponsive parents for women, father unemployment, and over-supporting parents applied the family-related trends as the main causes of addiction. In terms of the social factors, relationship with addicted friends in both sexes, unemployment for women, living in impoverished areas, of drug propagation, and the sense of deprivation from major social facilities are included. Minimum age of abuse initiating was 16 in men and 7 women. In both sexes, most addicts have begun in 17. The mean of abuse initiating was 20 in men and 19 in women. Both sexes began abuse professionally in 22/5 years of age. Men used to begin their abuse with cigarettes, hookah, glass, alcohol, crack, opium, marijuana or sedative drugs and women began by cigarettes, hookah, alcohol, marijuana, sedatives and X tablets. After changing their abuse and at the time of drug withdrawal, in addition to the increase in the mean in consumption of the previous used drugs, in both sexes, heroin, molasses, burnt opium, Buprenorphine and cocaine were also added. Although glass and crack was not found in the women beginners, they were added to the abused drugs at the withdrawal time. Most of the men after one year (holding the mean 2.73 years) and women after six months of abuse (holding the mean 1.71 years) changed their abuse from light to heavy. Feeling no pleasure from the previous drug was the most common cause of drug change in men, and in women, in addition to the shared reason with men, greater access to and exposure in new drug were important reasons for changing drug. Most of the addicts felt addiction after one year of abuse. For both sexes, friends and workplace were the major drug suppliers. Conclusion The results showed that several factors affect adolescents’ and young adults’ attitude toward drug, many of which are directly related to individual and family features. The use of national media in training people in immunizations and informing them about the risks and side effects can be effective in reduction of the damages Keywords Industrial Drug Abuse, Causes of Trends in Drugs, National Media Developing a Screening Tool for Prevention of Smoking among Students: Construct Validity Marzieh Araban1, Mahmood karimy2, Ali Montazeri3 1. Public Health Department, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran 2. Public Health Department, Saveh University of Medical Science, Saveh, Iran 3. Mental Health Research Group, Health Metrics Research Center, IranianInstitute for Health Sciences Research, ACECR, Tehran, Iran Background and Aim Prevention of youth smoking is an important public health concern. Although several instruments have been proposed for prevention of smoking behavior, none are intention-based. Hence, the aim of this study was to test validity and reliability of a new intention-based tool for prevention of smoking among student. Methods An extended version of theory of planned behavior (TPB) was considered as conceptual framework for this study and item pool was provided for developing a questionnaire. After careful consideration and performing content and face validity, a 37-item measure was developed and a sample of students completed the questionnaire. Reliability was estimated using internal consistency and validity was assessed performing confirmatory factor analysis (CFA), and known group comparison. Results In all 170 students were took part in the study. The mean age of students was 21.23 ± 2.9 years. The findings of content and face validity showed almost perfect results both for content validity ratio (CVR = 1) and for content validity index (CVI = 1). The confirmatory factor Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S9 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall analysis indicated a good fit to the data, and known group comparison revealed satisfying results (p<0.05). Internal consistency as measured by the Cronbach’s alpha coefficient was found to be 0.91. Conclusion In general, the findings suggest that this new developed scale is a reliable and valid theory based measure of smoking prevention for students. Since this instrument investigates both intention and its correlates as the most prominent predictors of smoking behavior, it could be used as a screening tool for prevention of smoking among students in early stages. Keywords Students, Smoking, Prevention, Intention, CFA Comparison of Effectiveness of Behavioral Group Therapy and Cognitive - Behavioral Group Therapy on the Sip Rate and Persistence in Treatment of Addict to Opium Patients under Treatment of MMT Vajiheh Armanmehr1, Mohamad Ali Aslinejhad2, Mahdi Moshki3 1. Social Development and Health Promotion Research Center, Gonabad University of Medical Sciences 2. MSc of Clinical Psychology, Department of Psychosocial Health, Deputy of Health, Gonabad University of Medical Sciences, Gonabad, Iran 3. PhD of Health Education, Assistant Professor, Department of Public Health, School of Health; And Social Development & Health Promotion Research Center, Gonabad University of Medical Sciences, Gonabad, Iran Background and Aim The purpose of this study was to determine the effectiveness of Behavioral group therapy and Cognitive - Behavioral group therapy on the slip rate and persistence in treatment of addict to opium Patients under Treatment of MMT Methods In a quasi-experimental study, 66 patients referred to the government clinic of substance abuse treatment in Gonabad city were selected among108 persons based on research criteria and in a randomly, put in two Experimental groups and control group. One of Experimental groups has received behavioral therapy group and other cognitive - behavioral therapy group during 12 group one -hour sessions weekly and Control group received MMT treated with usual individual interventions of clinic. Participants were evaluated with structured interview of opioid consumption index, slip rate and absence checklist based on the urine morphine test, before starting treatment, end treatment and follow up six months after the end of the group treatment. Data were analyzed with statistical methods of t, one-way analysis of variance and chi-square test. Results Results showed that both behavioral group therapy and cognitive - behavioral group therapy approach compared with usual individual interventions was more effective in reducing of slip rate after the intervention (p<0/0001), after 6 months of follow-up (p<0/001), and persistence in treatment (p<0/0001). Also, cognitive - behavioral therapy Group compared with behavioral therapy group was more effective in reducing of slip rate (p<0/05), and persistence in treatment (p<0/05). Conclusion to more effectiveness of MMT treatment, being associated with cognitive behavioral group therapy is recommended. Keywords Group therapy, Methadone, Slip The Role of Social Support on Durability of Quitting of NA Group Members Alireza Nili Ahmadabadi 1, Marzieh Haghgooe Esfahani2, Noorallah Moradi Kolahloo3, Vajiheh Armanmehr4 1. MSc in Public Administration 2. MSc in Sociology, Structor of Esfahan University 3. MSc in Social Welfare, Social Development & Health Promotion Research Center, Gonabad University of Medical Sciences 4. MSc in Sociology, Social Development & Health Promotion Research Center, Gonabad University of Medical Sciences, Gonabad, Iran Background and Aim In recent years, different investigators have studied the problem of preventing and remedy of addiction from medical, psychological and social aspects and have presented different solutions for this matter. But none of these solutions have led to absolute remedy. This research has been study the effect of receiving protection from social relationship networks on the durability of quitting. Methods The population of research was all members of Isfahan NA association at1390. The sample was 113 people who was selected through cluster sampling and responded to the valid and reliable questionnaire. Data were analyzed by using SPSS software-16. Results The results showed that if the relationships of these people were more with this association after quitting and if they were encountered with more information and instructions, they would have more durable quitting. Also, the correction of relationship with family and relatives and their emotional and altitude protection would have a meaningful effect on quitting of these people. But the financial protection didn’t have any meaningful relations with quitting durability. Conclusion Based on the results of this research, there is a need for addict person to receive cognitive, emotional and altitude supports after leaving drugs and also he needs to restore his position in the family and society in order to be a successful quit. Therefore it is suggested that quitting camps should provide some training facilities for families about supporting needs of addicts after quitting Keywords Quitting durability, Social Support, Narcotics Anonymous (NA). Comparison of Social Support and Resiliency Between the Three Groups of Addicted, Non-Addicted and Ex-Addicted Women Maliheh Arshi1, Elham Rostami2, Marzieh Takaffoli3 1. Assistant Professor, Department of Social Work, University of Social Welfare and Rehabilitation Sciences S10 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall 2. University of Social Welfare and Rehabilitation Sciences 3. Allameh Tabataba’i University (ATU) Background and Aim Statistics declares that the number of addicted women is going to increase also recent evidence suggests that two factors of social support and resiliency have significant difference between three groups of addicted, non-addicted and ex-addicted men .This study aimed to compare these two factors between the three groups of addicted, non-addicted and ex-addicted women. Methods During the study, 60 women of each group of hospitalized women in TC center of “Chitgar’s women” and ex-addicted referred women to “Tavallode dobare” center were selected. These women completed Waxes social support (1986) and Conner & Davidson resiliency (2003) questionnaires. Reliability and validity of Waxes social support questionnaire was confirm by Ebrahim Ghavami(1371) through 100 university students and 200 pupils of Iran. Reliability ratio of university student sample was 0/90 and 0/70 for pupils, and it was 0/81 in test-retest of pupils after six weeks. Mohamadi(1384) has used Cronbach Alpha to validated the resiliency questionnaire and gained validity ratio of 0/89 . KMO and Kroit Bartlett test was calculated before exploring the factors based on correlation matrix to assess the reliability of the questionnaire. The value of KMO was 0/88 and X2 value at Bartlett test was 5556/28 and so both values determined the adequacy of evidence to factor analysis. Then both groups were homogenized through three demographic variables of age, education and habitant and 25 cases were selected from each group. After all 25 non-addicted women that have been matched to the homogeneous characteristics were selected Results These results suggest that the amount of social support and resiliency between addicted and ex-addicted women & non-addicted and ex-addicted women have significant difference. Also, the results revealed that realized social support and resiliency between addicted and ex-addicted women have significant difference. Finally among these groups, considering social support the groups of ex-addicted women and about resiliency non-addicted women have the highest grade. Conclusion The results clearly indicate that non-addicted group of women doesn’t receive more social support in comparison to other groups and their resiliency also doesn’t have any significant difference. But the group of ex-addicted women receives more social support; it might be because women wouldn’t meet required social support unless they faced serious problems about their family and themselves. From these results it is argued that in subject of addiction, resiliency of women isn’t as influencing as it is for men and maybe other factors like personality, environment, culture and family beliefs about addiction have more affect. Keywords Support, Resiliency, Addicted Women, Non-Addicted Women, Ex-Addicted Women Validity and Reliability of the CAGE Questionnaire amongst Middle-Aged and Older Adults in Khuzistan Province of Iran Abdolrahim Asadollahi1 1. Australian Centre for Quality of Life, Deakin University, Melbourne, Australia Background and Aim The CAGE questionnaire, an instrument for attempts to Cut down on drinking, Annoyances with criticisms about drinking, Guilt about drinking, and using alcohol as an Eye opener. It have been pervasive simple tool to screen in busy medical settings where there is limited time for adult patient interviews and popular in nursing. Methods About 382 men with age range of 45 to 80 and with the mean age of 54.7±3.65 were sampled with the cluster-ratio sampling method from the eight medical centers and hospitals of Khuzistan province in southwestern Iran. The aged samples replied to the 4 items of CAGE. Results Coefficients of Cronbach’s alpha (α=.74), convergent validity (.72), divergent validity (-.12), and criterion validity (.78) were estimated, which were significant at ρ<.01. The exploratory factor analysis demonstrated that the 4–items of the CAGE for aged samples are organized into one factor (psychic & behavioural) which clarify 94 per cent of the scale’s variance. Second-order confirmatory factor analysis pointed out that the factor are well matched up onto a principal factor. Consequently, the 1-factor model was well appropriate for the data by the fit index techniques for adjusting the scale (AGFI=.88, GFI= .94, RMSEA=.002, IFI=.95, NFI= .90, CFI=.93). Conclusion The results pointed to the well-adjusted reliability and validity of the CAGE and its usefulness for the relevant studies as well. Keywords Aged, Alcoholism/Complications, Alcoholism/Diagnosis*, Alcoholism/Psychology, Analysis of Variance, Cognition Disorders/ Etiology, Cognition Disorders/Psychology, Female, Humans, Male, Middle Aged, Iran The Relationship between External Locus of Control and Learned Helplessness in Individuals with a Tendency Toward Drug Addiction Centers Located Mojtaba Ashouri1, Farzane Piran2, Masuome Rahbar3, Eskandare Rahbar4, Esmat Nasiri5, Rahim Ganjkhanlu6 1. Master of Educational Psychology, Urmia University, a Visiting Member of Payam Noor University 2. MA in Clinical Psychology, Rehabilitation Specialist Zanjan 3. MA in Clinical Psychology, Rehabilitation Specialist Zanjan 4. B Physiotherapy Assistant Rehabilitation Organization Intelligence City 5. MA in Clinical Psychology, Rehabilitation Specialist Zanjan 6. MB in Clinical Psychology, Rehabilitation Specialist Zanjan Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S11 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Background and Aim One of the most important concepts in the field of psychology, the concept of drug addiction and the tendency is that researchers and theorists from various aspects such as psychology, the concept of locus of control and learned helplessness to study and analyze the have paid. Therefore, the present study aimed to investigate the relationship between external locus of control and learned helplessness in individuals with a tendency toward drug addiction centers were established. Methods analysis of covariance Results The group Craft had more succesful in entering Patients to treatment than the other groups.Also the Craft group have got lower number in Beck inventory and higher numbers in QOL after intervention than the other groups. Conclusion Methods This cross-correlation and the population settled in the city Intelligence addiction centers in 92, 50 people were selected by purposive sampling Rutter standardized questionnaire for the variable External Locus of Control Scale and Seligman Learned Helplessness been used for assessment. Data using descriptive statistics and Pearson correlation analysis was used. Results The results showed that Pzhhsh external locus of control and learned helplessness, a significant positive correlation (01/0> p, 43/0 = r) with each other, and the other two variables together, a significant positive correlation based on their degree of addiction addiction centers (01/0> p, 41/0 = r), respectively. Conclusion The present study showed that higher external locus of control and learned helplessness, the rate of drug addiction centers based on population increases. ¬ So we can say that external locus of control and learned helplessness, an important factor in the prevention and treatment of substance abuse, and family health are the result. Craft is effective in entering addicts to treatment and can help Families to reduse depression and increase Quality of life. Keywords Craft-Substance Abuse, Families Naloxone can Prevent Seizure Induced by Tramadol during Kindling Model of PTZ in Mice Ramin Ataee1, Yazdan Noorian2, Mohammad Shaterpour3, Amin Ataie4, Somayyeh Nouri5 1. Pharmaceutical Sciences Research Center,Mazandaran University Of Medical Sciences,Sari Iran 2. Pharmaceutical Sciences Research Center,Mazandaran University Of Medical Sciences,Sari Iran 3. Pharmaceutical Sciences Research Center,Mazandaran University Of Medical Sciences,Sari Iran 4. Department of Pharmacology, Babol University Of Medical Sciences, Babol Iran 5. Pharmaceutical Sciences Research Center,Mazandaran University Of Medical Sciences,Sari Iran Background and Aim Keywords External Locus of Control, Learned Helplessness, Addiction, Addiction Centers Based Subjects Efficacy of “Community Reinforcement And Family Training” (Craft) in Motivating Patients Hossein Assadbeigi1 1. University of Social Welfare Background and Aim To assess the effectiveness of the method «Craft» (Community Reinforcement And Family Training) the likely reluctance of addicts to treatment, 75 family members of drug users in 3 groups of 25 Craft, Naranon and non-intervention groups. In the first session, and after about 2 months, Depression and quality of life of these Concerneded Significant Others where assessed by the Beck Depression and World Health Organization Quality of Life Questionnaire (WhoQOL). On the other hand after 2 months the stages of change, from precontemplation to contemplation and preparation in drug abuse patients were assessed. The results showed that the Craft was more successful than the other groups to change their patients from stage 1 to 2 and 3of change for interin treatment. Also the Craft was more successful than the other groups to reduce depression and increase the quality of life of the families. Naloxone is an opioid antagonist drug developed by Sankyo in the 1960s.Naloxone is a drug used to counter the effects of opiate overdose, for example heroin or morphine overdose. Naloxone is specifically used to counteract life-threatening depression of the central nervous system and respiratory system. Naloxone has an extremely high affinity for μ-opioid receptors in the central nervous system. Naloxone is a μ-opioid receptor competitive antagonist, and its rapid blockade of those receptors often produces rapid onset of withdrawal symptoms. Naloxone also has an antagonist action, though with a lower affinity, at κ- and δ-opioid receptors. Tramadol is a centrally acting opioid analgesic used to treat moderate to moderately severe pain. Tramadol is a serotonin releaser, reuptake inhibitor of norepinephrine and a weak μ-opioid receptor agonist. Seizures and serotonin syndrome are amongst the more commonly reported serious adverse reactions attributed to tramadol. According to this background we have tried to examine if naloxone can prevent seizure induced by tramodole in PTZ kindling model in mice. Methods For this purpose we have induced myoclonic seizure in mice with increasing doze of PTZ injected subcutaneously and for this aim the 5 mice in one group received increasing doses of PTZ and after finding minimum and maximum dose of threshold for PTZ,5 other mice have received five increasing dose of Tramadol IP in another separate group and the minimum and maximum doses of S12 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Tramadol which induced myoclonic and HLTE seizure in mice have been destinguished(5 and 30 mg/kg) and in two other groups of five mice Naloxone in increasing doses of (5,10,20,30,40,50 mg/kg) injected IP, 30 minute before minimum and maximum doses of tramadole and 45 min before maximum doses of PTZ and the number of mice which have shown myoclonic or HLTE seizures were numbered in each group and compared with control. The comparison between groups was analyzed with one-way ANOVA test with SPSS 21. Results Our results have been shown that tramadole can enhance the seizure intensity of PTZ and naloxone can prevent tramadole seizure in 40mg/Kg in mice significantly Conclusion According to our results we can conclude that some seizure mechanisms of tramdole can be through activating of µ-Opioids receptor which can be antagonized with an competitive pure antagonist as naloxone and we can suggest this method of treatment for clinical trials of tramdole intoxications Keywords Tramadole,Toxixology,Seizure,Naloxone Intra-locus Coeruleus Microinjection of Orexin-A Induces Opioid With drawal-Like Behaviors in Morphine Dependent Rats Hossein Azizi1, S. Mohammad Ahmadi Soleimani2, Saeed Semnanian3 1. Tarbiat Modares University 2. Tarbiat Modares University 3. Tarbiat Modares University Background and Aim Orexin (hypocretin) neuropeptides have been shown to play a pivotal role in opioid withdrawal behaviors. Hypothalamic orexinergic neurons send dense projections to the locus coeruleus nucleus (LC). Withdrawal syndrome is temporally associated with the hyperactivity of LC neurons. The reported increase in LC neuronal activity seems to be mediated by extrinsic factors. This study was conducted to investigate whether intra LC microinjection of orexin-A induces opioid withdrawal symptoms. Methods Adult male Wistar rats weighing 250-300 grams were rendered dependent on morphine by subcutaneous injection of morphine sulfate (10 mg/kg, s.c.) at an interval of 12 h for 9 days. On day 10, intra-LC microinjection of orexin-A (100 μM, 200 nl) was performed two hours after morphine administration. Thereafter, somatic signs of withdrawal were evaluated in a plexiglas test chamber (30 cm diameter, 50 cm height) during a period of 25 min. Results Orexin-A induced several signs of morphine withdrawal syndrome (chewing, scratching, rearing, teeth chattering, wet-dog shake and paw tremor). Conclusion It seems that orexin-A acts as an extrinsic factor in the expres- sion of morphine withdrawal syndrome in LC nucleus. Keywords Orexin-A, Morphine Withdrawal Syndrome, Locus Coeruleus, with drawal-Like Behavior, Rat Female Drug Users are Heterogeneous Groups: Few Facts Shokatalmolouk Azizzadeh1, Molouk Azizzadeh2, Shaditalab3, Sonia Ghaffari4, Parisa Nakhaei5 1. UNODC 2. UNODC 3. Tehran University 4. UNODC 5. UNODC Background and Aim The latest Rapid Assessment reports the share of women among all drug users as close to 5% (Narenjiha et al. 2008) without reporting gender disaggregated data to the public. In 2014, it has increased up to 10%. With limited data on the FDUs (Female Drug Users) and those entering treatment centers, we know very little about FDUs. In absence of comprehensive information, scattered studies are probably the only source of information and present article aims at providing some information on FDUs and the heterogeneity of the group which is important in development of services. Methods Secondary analysis of available information on FDUs in three different institutions in Tehran during the year of 2011 is applied. 315 FDUs’ socio-economic data was extracted from their records by strict confidentiality. Data on few shared items among institutions demonstrates how social background of women who refer to three types of treatment different regions of the city differs. Results Age and preferences of treatment: Nearly 30% of women drug users were younger than 29 years of age and 30% in each of the age groups of 30-39 and 40-49. Almost half of camp residents are in the age category of 19-29 (young). It seems short term abstinence treatment has more attraction for younger DUs. Education is not a hindering factor; 11% of FDUs are illiterate and 30% have few years of primary school. Large number has attended few years of secondary school and 25% have high school diploma. While Illiterates and less educated are mostly in the south of Tehran, 23% of women in out-patient, long term abstinence treatment have university degrees. Broken families: Approximately 85% of FDUs have been married once. More than 30% are divorced and 15% have reported their marriage status as “temporary marriage”. Early marriage under 18 is reported among majority. Safety in houses: A small group of FDUs in south of Tehran are working either as the employees of DICs (11%) or as unskilled labor in cleaning jobs, packing workshops or peddler in the street (30%). However, majority in out-patient treatment institute are housewives, which goes against the notion that women are safe in staying at home. 16% of all FDUs and approximately 40% in south of Tehran reported that they work in sex market. Risk behaviors: Almost 30% of MMT clients have had drug injecting experience in some point of their life and the Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S13 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall share of those injecting drug users is almost 11 % in total interviewees. Conclusion The FDUS are not a homogeneous group and with limited data on 315 samples two distinct groups are recognized. Center of Tehran: Majority with marriage experiences “Housewives”. Those employed are working in white collar jobs or self-employed. Financially are supported by family. South of Tehran: older, less educated and relatively poor with limited resources. Almost all have married once or more and at present 70% are living on their own. It seems permanent marriages do not hold their spouses responsible for providing households’ expenditure. Conclusion All patients presenting after DSH need to be carefully screened for alcohol disorders and for comorbid psychiatric diagnoses. Treatment of DSH patients with alcohol disorders should include the treatment of any comorbid depressive illness Keywords Deliberate Self-Harm(DSH) , Alcohol Disorders , Damghan. The Efficacy of Acceptance and Commitment Therapy on Reduction of Anxiety Symptoms in Substance Abuses Keywords Mozhgan Kazemi1, Fatemeh Badri2 1. Psychology Department, Roudehen Islamic Azad University, Roudehen,Iran 2. Psychology Department, Roudehen Islamic Azad University, Roudehen,Iran A Study on the Incidence of Deliberate Self-Harm Patients with Alcohol Disorders Referring to the Emergency Room of Baradaran e Rezaee Hospital in Damghan, Iran(2009-2014) Background and Aim Female Drug Users, Heterogeneous Groups, Treatment Masaudeh Babakhanian1, Masumeh ghazanfarpur2, Soraya Sayar3, Ahmadreza Khanbeiki4 1. Social Worker, Department of Social Work, Velayat Hospital, Semnan University of Medical Sciences, Damghan, Iran 2. Faculty of Nursing and Paramedics, Mashhad University of Medical Science, Iran 3. Iran university of Medical sciences, Shaheed Rajaeis Cardiovascular Medical and Research Center. Tehran, Iran 4. Soidier Education Center and Air Defence of Seman Background and Aim Deliberate Deliberate self-harm (DSH) patients with alcohol problems present a considerable challenge for clinical services. The current study was conducted to explore the prevalence and reasons associated with the incidence of DSH in a group of patients referring to the emergency room of Baradaran e Rezaee Hospital in Damghan, Iran. Methods Fifty four clients with the mean age of 29.4 (±10.3) years participated in this cross-sectional study in 2009-2014. Firstly, demographics and details of substance use were collected based on items with an ICD-10 diagnosis of alcohol dependence or harmful use of alcohol and a researcher-made questionnaire. Then details of comorbidity and factors associated with the current DHS were collected by a semi-structured interview. Data were analyzed by performing descriptive methods of statistics Results Conflict and aggression (44.8%) , intoxication whit opiate and drug (35.2%) and body cutting and vessel cutting (20%) were the most prevalent types of deliberate self-harm. Furthermore results revealed that comorbidities such as physical illness (38.9%) and psychiatric disorders including depression (46.5%), bipolar disorder (5.6%), stress and anxiety (7.5%) were commonly prevalent. The most frequently reported factors associated with DSH were desires for emotional sufferings (33%), experiencing euphoric feelings (24%), and stress (62%) respectively. Recently a lot of discussions has about cognitive- behavioral interventions(the third wave) especially in the area anxiety disorders.Acceptance and Commitment Therapy (ACT) is an innovative acceptance-based behavior therapy that has been applied broadly and successfully to treat a variety of clinical problems, including the anxiety disorders. Throughout treatment ACT balances acceptance and mindfulness processes with commitment and behavior change processes. This study investigated the effectiveness of Acceptance and Commitment Therapy, in reduction of anxiety symptoms in individuals with suffer addiction Methods In this study which was a Quasi-Experimental with pre-test, post-test and control group, the sample group was selected in by available sampling method from addicts that inhabit in Ahd v Pyman Rahaei Camp in Ghods city that selected. After screening and determination rang of anxiety , a sample of 30 addicts randomly assigned into the experimental(n= 15) and control(n= 15) groups. The experimental group underwent eight, two-hour sessions of Acceptance and Commitment Therapy and the control group didn’t receive any therapeutic treatment.the tools that used in this study was beck Anxiety Questionnaire that completed by participation in the pre-test and post-test stages. Results Data was analyzed by Covariance showed ,Significant difference between the scores of the experimental and control groups. (p:0/00) Conclusion Results from this study suggest that Acceptance and Commitment Therapy can be effective intervention for decrease the anxiety and Helps people to achieve psychological flexibility. Keywords Anxiety, Acceptance and Commitment Therapy, Substance Abuse S14 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Early Menopause, Association with Addiction, and Lifestyle Factors in Diabetic Patients Mahvash Bagheri , Behrooz Khiabani Tanha 1. AREN Neuroscience Center 2. Member of Iranian Epidemiologic Association 1 2 Background and Aim Early onset of menopause is a risk factor for several health problems. The objective was primarily to investigate the association between early menopause and addiction in diabetic patients Menopause, Addiction, Lifestyle, Diabetic The Effectiveness of Matrix Intervention in Group in Reducing Methadone Use and Relapse Prevention in Methadone Treatment Arva Bakhtiari1, Hossein Eghbali2, Nader Monirpoor3, Vahid Ahmadi4 1. Department of Clinical Psychology, Islamic Azad University, Qom Branch 2. Department of Clinical Psychology, Islamic Azad University, Qom Branch 3. Department of Clinical Psychology, Islamic Azad University, Qom Branch 4. Department of Psychology, Payam Noor University, Ilam Branch Background and Aim Methods The present population-based cross-sectional study included a sub-sample of 100 Postmenopausal women diabetic born in 1950–55 who participated in MASHAD. Early Menopause was defined as menopause occurring at an age of less than 45 years. We applied logistic Regression analyses (crude and adjusted odds ratio (OR)) to examine the association between early Menopause and selected lifestyle factors in addicted. : The present population-based cross-sectional study included a sub-sample of 100 Postmenopausal women diabetic born in 1950–55 who participated in MASHAD. Early Menopause was defined as menopause occurring at an age of less than 45 years. We applied logistic Regression analyses (crude and adjusted odds ratio (OR)) to examine the association between early Menopause and selected lifestyle factors in addicted. : The present population-based cross-sectional study included a sub-sample of 100 Postmenopausal women diabetic born in 1950–55 who participated in MASHAD. Early Menopause was defined as menopause occurring at an age of less than 45 years. We applied logistic Regression analyses (crude and adjusted odds ratio (OR)) to examine the association between early Menopause and selected lifestyle factors in addicted. : The present population-based cross-sectional study included a sub-sample of 100 Postmenopausal women diabetic born in 1950–55 who participated in MASHAD. Early Menopause was defined as menopause occurring at an age of less than 45 years. We applied logistic Regression analyses (crude and adjusted odds ratio (OR)) to examine the association between early Menopause and selected lifestyle factors in addicted. Results Addiction was significantly associated with early menopause (adj. OR, 1.59; 95% CI, 2.11–2.28). Stopping addiction more than 3 years before menopause considerably reduced the Risk of early menopause (adj. OR, 0.13; 95% CI, 0.05–0.38). Total exposure to smoking (the product of number of cigarettes per day and time as a smoker) was positively related to early menopause. Menopause Of the lifestyle factors tested, high educational level (adj. OR, 0.50; 95% CI, 0.57–0.79) and high social participation (adj. OR, 0.70, 95% CI, 0.41–0.98) were negatively associated with early menopause. Conclusion Keywords This study shows an association between addiction and menopause. The data also suggest that the earlier a woman stops addiction the more protected she is from early menopause. To evaluate the effectiveness of matrix interventions in the relapse prevention and daily dosage of methadone was the main goal of this research. Methods In a semi-experimental design, 24 male patients with diagnosis of substance dependence according to DSM-IV were put in two experimental and control groups randomly. Participants were evaluated by urine test each two weeks and the follow-up phase was one year after the end of treatment(behavioral - cognitive therapy, family thrapy and relax thrapy).Control group with no psychological treatment only took methadone. Data were analyzed using covariance analysis, chi square. Results Results showed that the effect of matrix interventions on reducing relapse and methadone use (p < 0.05), and increasing the length of stay in treatment (01/0 P <). Conclusion it seems that matrix intervention in group, while increasing the effect of methadone treatment, and reducing dosage of methadone. Conclusion It seems that matrix intervention in group, while increasing the effect of methadone treatment, and reducing dosage of methadone. Keywords Matrix Interventions, Daily Using of Methadone, Relapse Prevention. The Alcohol Consumption Pattern among the Students and its Relationship with Personal Characteristics Amir Balashi1 1. University Background and Aim The goal of his study is the survey of the relationship between the alcohol consumption and the education. Methods Information is descriptive and the metering class. In this Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S15 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall context, the population 500 students of Tehran University as random sampling are used and the questionnaires were set and distributted. Results Statistical analysis done by descriptive, have been undertaken by comparative tables. Between school years, 30% of undergraduates use alcohol, 44.7% of Mas use alcohol and 33.3% of PHDs sue alcohol. Alcohol consumption among undergraduate school years has been 68/3%. 17.5% of them used once during last month and 7.5% of them used once during last week. Conclusion The alcohol consumption has been applied with studying the social characteristics and demographics. This study shows that there is relationship between the alcohol consumption and the education. Keywords Alcohol Consumption, School Years, Education, Statistical Analysis The Role of Risk Perception and Self-Reflection in Prediction of Motivation for Substance Dependence Treatment Sajjad Basharpoor1, Alireza Jafartabar 2, Mohammad Narimani3, Omid Massah 4 1. University of Mohaghegh Ardabili 2. University of Mohaghegh Ardabili 3. University of Mohaghegh Ardabili 4. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran Background and Aim Motivation for treatment is a key element in treatment and recovery of substance abuse disorders. The current study was conducted to investigate the role of risk perception and self- reflection in prediction of motivation for treatment in people with substance dependence. Methods This survey study was conducted to determine correlation. The statistical population of this study comprised all those with substance dependence who were referring to Ardabil’s addiction treatment centers in the second half of 1392. One hundred and forty people were selected from this population through multistage random cluster sampling. They were asked to complete the questionnaires of risk perception, self- reflection and motivation for treatment. Data were analyzed using Pearson’s correlation and multivariate regression tests. Results Motivation for treatment was positively associated with risk of drug abuse (r=0/26; p<0/003), risk of aggressive behavior (r=0/47; p<0/001), Risk of sports activities (r=0/21; p<0/015), risk of academic and professional failures (r=0/68; p<0/001), risk of sexual activity (r=0/31; p<0/001), and risk of heavy drinking (r=0/43; p<0/001). It was also positively associated with the total score of self-reflection and insight (r=0/24); p<0/006) and the need to self-reflect (r=0/42; p<0/001). Fifty percent variance of motivation for treatment was explained by risk perception and 19% was explained by self-reflection in the multiple regression analysis results. Conclusion The results of this study demonstrate that high perceived risks of drug induced behavior and high ability for self-reflection can predict motivation for treatment and readiness for change in drugdependent individuals. Keywords Risk Perception ,Self-Reflection, Treatment Motivation , Drug Dependence Comparison of Executive Function and Difficulties in Emotion Regulation in Addicted with Upper and Lower Borderline Personality Traits Masoumeh Movahedi1, Ali farhadi2, Yazdan Movahedi3, Haniyeh kharrazi4, Ahmad Bayat5 1. MA of Family Counseling, Lorestan University of Medical Sciences, Korramabad, Iran 2. PhD, Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran. 3. Ph.D. Student of Cognitive Neuroscience, Psychology, Psychology and Education, Tabriz, Iran 4. MSc Clinical Psychology, Tabriz University of Medical Sciences, Tabriz, Iran 5. MSc Child and Adolescence Clinical Psychology, Psychology and Education, Tabriz University, Iran. Background and Aim The aim this study was compare the executive function and difficulties in emotion regulation in addicted with upper and lower borderline personality traits. Methods The current study is kind of causal – comparative. The study population, was included all men substance use drug which referred to treatment center of Khoy city in 2013. 80 people addicted, were selected through available sampling method and by borderline personality traits questionnaire (STB) in two groups of 40 people through drug abusers with borderline traits were high and low. Thus the Wisconsin card sorting test and the scale of the difficulties in emotion regulation were performed on the two groups. Data in SPSS 20 program by statistical method multivariate analysis of variance (MANOVA) and LSD test were analyzed. Results The results indicated that addicts with high borderline traits than to addicts with lower borderline traits in Wisconsin card sorting test has lower performance and higher total number of errors (P = 0/002) and error perseveration (P = 0/010). Also addicts with high borderline traits, have higher scores on the difficulties in emotion regulation variable (P = 0/002) than to addicts with lower borderline traits. Conclusion This study showed that drug abusers with high borderline traits, the poorer performance in executive functioning and higher levels of difficulties in emotion regulation which this could be due to the influence of drug dependency on their neurological function which leading to poorer performance this individual than addicts with lower borderline traits. Keywords Executive Functioning, Difficulties in Emotion Regulation, Borderline Personality Traits, Addiction S16 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Study of Cognitive Function (Executive Functions and Memory) in Addicts Substance Abusers, Addicts Treated with Methadone and Normal Individuals Ali Farhadi1, Masoumeh Movahedi2, Yazdan Movahedi3, Ahmad Bayat4 1. PhD, Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran. 2. MA of Family Counseling, Lorestan University of Medical Sciences, Korramabad, Iran 3. Ph.D. Student of Cognitive Neuroscience, Psychology, Psychology and Education, Tabriz, Iran 4. MSc of Child and Adolescence Clinical Psychology, Psychology and Education, Tabriz University, Iran. Background and Aim The purpose of this study was compare cognitive functioning addicts substance abusers, addicts treated with methadone and normal individuals. Methods The current study is kind of causal – comparative. Statistical population of this research includes all substance abusers (men) that referred to addiction treatment center in khoy, 1392. The sample consisted of 40 patients treated with methadone, 40 person drug addicts (self-represented), and 40 person non-addicted individuals who were selected in available method. We administered for 3 groups the Wisconsin card sorting test and the Wechsler memory scale. The data was analyzed by SPSS version 20 using multivariate analysis of variance (MANOVA) and Tukey test. Background and Aim The aim study was to compare the degree of general health and social support in addicted and non-addicted people. Methods The method of this study was causative-comparative. The statistical population of the study involves all addicts who had referred to addiction treatment centers in Khoy in 1391. 60 people were selected out of this population by available sampling, and 60 normal people were cloned on the basis of age, gender, and education. Measurement tools include Goldberg General Health (GHQ-28) and social support (Fleming) questionnaires. Data analysis was performed using SPSS software, ANOVA (Multivariate Analysis Of Variance) method, and Bonferroni test. Results This study indicated that mental health (P < 0/0001, F=36/26) and social support (P < 0/0001, F=27/36) are lower in addicts than non-addicts. Conclusion The results showed that mental health and social support are lower in addicted people compared with others. Thus, it is suggested that since mental health is highly influenced by social support, influential factors in low levels of social support in addicts requires further investigation. Keywords Mental Health, Social Support, Drug Abuse Results The results showed that functioning addicts’ substance abusers group compared to addicts treated with methadone group and normal individual as well as the functioning addicts treated with methadone group compared to the normal group. There was a significant difference in the Wisconsin test and Wechsler memory scale (p ? 0/05). However, perseveration error there was no significant difference in addicts threated with methadone and normal individual. Conclusion Chronic use of psychoactive substances will be cause damage to multiple brain regions such as the prefrontal cortex and hippocampus, resulting in impaired cognitive function in these areas. Keywords Cognitive Function, Executive Functions, Memory, Drug Substance Abuse Comparison of General Health and Social Support in Addicts and Non-Addicts Ali Farhadi , Masoumeh Movahedi , Yazdan Movahedi , Haniyeh kharrazi , Ahmad Bayat5 1. PhD, Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran. 2. MA of Family Counseling, Lorestan University of Medical Sciences, Korramabad, Iran 3. Ph.D. Student of Cognitive Neuroscience, Psychology, Psychology and Education, Tabriz, Iran 4. MSc Clinical Psychology, Tabriz University of Medical Sciences, Tabriz, Iran 5. MSc Child and Adolescence Clinical Psychology, Psychology and Education, Tabriz University, Iran. 1 2 3 4 Parental Substance Abuse and its Impact on the Mental Health of Children Masoumeh Movahedi1, Ali farhadi2, Yazdan Movahedi3, Haniyeh kharrazi4, Ahmad Bayat5, Reza Latifi6 1. MA of Family Counseling, Lorestan University of Medical Sciences, Korramabad, Iran 2. PhD, Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran. 3. Ph.D. Student of Cognitive Neuroscience, Psychology, Psychology and Education, Tabriz, Iran 4. MSc Clinical Psychology, Tabriz University of Medical Sciences, Tabriz, Iran 5. MSc Child and Adolescence Clinical Psychology, Psychology and Education, Tabriz University, Iran. 6. MA Clinical Psychology, Psychology and Education, Tabriz, Iran. Background and Aim Parental substance abuse and other contaminants related on is the risk factors that makes their children addicted. According to investigations, 44 percent of offenders live in Unbound families and 91 percent of this families are addicted. this study investigated the effect of parents addiction on mental health of children. Methods Sample include of 50 addicted person and 50 normal one .Goldberg mental health inventory with 28 questions was selected as research tool. Data were analyzed by SPSS-19 software. Method of this research was correlation. method of statistics analysis was descriptive and inferential and therefore used Pearson’s correlation. Results Results demonstrated children of addicted people had less mental Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S17 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall health than children of normal people. In addition children of addicted people were more depressed than children of normal people. Conclusion In families where one or both parents were addicted somehow all roles in families due to fragmentation and neglect of family collapses and principles governing an intimate gathering will be completely unstable. Keywords Parental Substance Abuse, Mental Health, Children The Efficacy of Group Cognitive – Behavior Therapy (GCBT) in Relapse Prevention in Methamphetamine Dependent People Fatemeh Behrouzian1, Mostafa Nokani 2, Hamid Reza Mohajerani3 1. M.A in Clinical Psychology Department of Psychology Science and Research Branch Islamic, Azad University Boroujerd, Iran 2. P.H.D in Clinical Psychology. Assistant Prof of Arak University of Medical Science 3. P.H.D in Physiology, Assistant Prof of Azad Arak University. Background and Aim The research purpose is to investigate the efficacy of group cognitive – behavior therapy (GCBT) in Relapse prevention in Methamphetamine dependent people Methods For this reason in a semi – experimental study and by accessible sampling method we selected_ 30 _clients as a sample. Research Tools included: diagnostic interview,and urine test. They were divided in to two groups, 15 _clients in experimental and 15 clients in control group. GCBT has been done on Experimental group for 12 weekly 1/5 hour sessions. Data is analyized by SPSS as well as statistical test such as chi- square Results The results showed that there is between rate of relapse of in experimental and control group were difference(p-value<0.05) Conclusion The group cognitive – behavior therapy is effective in prevention Relapse. Keywords Group Cognitive – Behavior Therapy, Methamphetamine Dependent People, Relapse Prevention Effectiveness of Active Learning Techniques in the Prevention of Drug Abuse for Pre-school Children Davood Behzad1 1. Department of Social Work, University of Applied-Science, Bandar Abbas Background and Aim The Importance of predisposing factors for addiction in early ages has caused considerable part of prevention programs focus on children. Children according to their living conditions are susceptible to psychological and social damage than other age groups. Hence the emphasis on drug prevention programs should start from early ages. The purpose of the present study is to assess the effectiveness of active learning methods as a strategy to prevention program for pre-school children. Methods The research method was a quasi-experimental pre-test and post-test with a group. The statistical population was preschooler’s children in Bandar Abbas. A sample of 53 children aged 4 to 6 years old were randomly selected and divided into two groups. The proposed educational package content consists of five areas in the three levels of knowledge, attitudes and behavior that include: self-knowledge, knowledge of the negative outcome and dangers of drugs and alcohol, understand and express emotions, get help in emergency (problem solving), ability to say no against unreasonable offers. This program presented by trained instructors in 10 weeks and 30 sessions for children. Results Preliminary results showed that pre-school children in the content area are generally below the median score. Children’s emotional perceptions were significantly weaker than other areas. Results showed that the active learning method has a significant effect on increasing knowledge, attitudes and behavior in children. Conclusion In conclusion, compared to the same content presented is an appropriate prevention program. With regard to children characteristics, its implementation in terms of the active learning methods is effective. Keywords Drug Abuse, Prevention, Active Learning, Preschoolers The Effectiveness of Acceptance and Commitment Therapy for the Treatment of Polysubstance Abuse: A Preliminary Investigation Saeid Dabagh Ghazvini1 1. Young Researchers and Elite Club, Roudehen Branch, Islamic Azad University, Roudehen, Iran Background and Aim Acceptance and Commitment Therapy (ACT) is one of the most influential third wave therapy with a considerable deal of practical evidence in treatment of substance abuse. This method subscribes the view that avoiding unpleasant personal experiences such as thoughts, feelings and bodily sensations is inescapable yet may causes disease, lead to treatment leave and additional drug abuse. The study was aimed to the effectiveness of acceptance and commitment therapy for the treatment of polysubstance adult abusers. Methods Participants were thirty polysubstance abuse disorder men referring to an addiction treatment center were randomly assigned to two groups, an intervention based on ACT and a control group on a waiting list. They assessed with the Situational Confidence S18 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Questionnaire (SCQ), the Craving for Drugs after Withdrawal Inventory (CDWI) and the Depression, Anxiety, Stress Scale (DASS-42) at pretreatment, at the end, and at a six-month followup. Urinalysis were applied once a week to determine the drug consumption. The treatment was administered in 45 to 60-min individual sessions. The normal session frequency was 2 sessions per week as long as all treatment was completed within 119 days. Results After 32 ACT intervention sessions, the multivariate analysis of covariance for assessment of the effects of the intervention showed that participants of ACT condition in comparison with control ones had a significant reduction in drug abuse, comorbid psychopathological symptoms, average of craving and a growth in self-efficacy. The results also illustrated that the rate of abstinence increased from 18.3 to 57.6 at the follow-up. Conclusion The findings support the last ACT studies regarding psychological maturation and flexibility. Having taken everything into consideration, the ACT intervention seems to be an effective and appropriate treatment choice for addictive behaviors and comorbid disorders in adult addicts. Keywords Acceptance and Commitment Therapy, Polysubstance Abuse, Third Wave Therapy, Psychological Flexibility Polypharmacy: An Invisible Addiction among Elderly Community Dwellers Ali Dadgari1, Seyed Abbass Mousavi2, Reza Chaman3, Tengku Aizan Hamid4, Mohmd Nazrul Hakim5, Lim Poh Hin6, Leila Dadvar7 1. Shahroud University of Medical Sciences 2. Shahroud University of Medical Sciences 3. Yasuj University of Medical Sciences 4. University Putra Malaysia-UPM 5. University Putra Malaysia-UPM 6. Universiti Putra Malaysia-UPM 7. Shahroud University of Medical Sciences Background and Aim Addiction among elderly people is a common phenomenon all over the world. An invisible form of addiction among elderly people is polypharmacy. Research has demonstrated that patients on polypharmacy are more likely to suffer drug side effects and that this is more related to the number of co-morbidities a patient has than age. Polypharmacy is defined as simultaneous consumption of 4-5 and more medication. The purpose of the study is to investigate Polypharmacy among Iranian elderly in Shahroud, Semnan provenience. Methods This study is a community survey regarding geriatrics health assessment. Subjects (n= 1123) of the study were selected from a big population (N=12123) according to their health record numbers. Inclusion criteria of the study were being 60 years old and above and living permanently in community under investigation. The instrument of the study was a Geriatrics Health Assessment tool to collect subjects’ health information. More data were collected from subjects’ health profiles in Community Health Centers. Results Of all subjects of the study, 634 person were male and 489 were female. Subjects of the study were living in rural (n=564) and urban (n= 559) areas. The mean age of the subject were 72±11 years. The average number of medication consumption among elderly people were 8.3. The results of the study showed that more than 88% of the elderly people were under polypharmacy. Polypharmacy were more common among female elderly people; however, there were no significant relationship between sex and polypharmacy. Other variables such as advanced age (p= 0.00), number of acute and chronic disease (p= 0.00) were significantly related to polypharmacy. Living place, living arrangement and functional status were not related to polypharmacy. Conclusion Polypharmacy is a common problem among elderly people. Prevalence of medications such as analgesics, sedatives and narcotics is in second rank of medications followed by cardiovascular and antihypertensive medications. Moreover, antipsychotic medications were third in rank of medication prevalence. Scientist believed that polypharmacy is a serious problem and needs to be reviewed and evaluated continuously. However polypharmacy is frequently under- diagnosed by primary care professional and families. Comparison of polypharmacy in European countries and Iranian elderly showed that the number of drugs used by Iranian elderly community dwellers is higher that all European countries. Keywords Addiction, Polypharmacy, Elderly, Community The Treatment Needs of Women with Methamphetamine Use: Implications for Implementing Cognitive-Behavioral Intervention Reza Daneshmand1, Leila Arshad2, Zahra Alam Mehrjerdi3, Zahra Ghenaatian4 1. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 2. Sarzamin e Khorshid Female Drop in Centre, Tehran, Iran 3. Program of International Research and Training, National Drug and Alcohol Research Centre, Faculty of Public Health & Community Medicine, University of New South Wales, Sydney, Australia 4. Chitgar Female Therapeutic Community Centre, Tehran, Iran Background and Aim Methamphetamine use has no approved pharmacological therapy. Cognitive-behavioural therapy is the main treatment option. Recently, methamphetamine use has emerged as a new critical health concern among women in Iran. There is no study in Iran to show the treatment needs of Iranian methamphetamine-dependent women. Methods To contribute to this understanding, a one-year survey study was conducted at the only female therapeutic community centre in Tehran in 2011. All participants (N= 500) were recruited. Data was analyzed by bivariate and multivariate analyses. Results The man age of the sample was 31.8 (SD=8.5) years old. 51.8% Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S19 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall were currently married while the remaining women were currently unmarried. The median years of education were nine years. Smoking was the main route of methamphetamine administration. Successful methamphetamine abstinence in the past was correlated with family support (AOR= 1.99, 95% CI: 1.68-2.22), employment (AOR =1.40, 95% CI: 1.2-1.90), receiving counseling and psychological services (AOR =2.20, CI: 1.92-2.52) and having a program for daily activities (AOR =1.30, 95% CI: 1.0-1.90). The most treatment needs for ceasing methamphetamine use included a need for learning motivations to change, strategies to cope with craving, dealing with a lapse, refusal skills and relapse prevention. Conclusion The study results showed the intertwined relationship among a number of factors in ceasing methamphetamine use among the sample. The treatment needs among the women should be specifically considered in tailoring cognitive-behavioral interventions for this group of drug users in the country. Keywords Women, Methamphetamine, Cognitive-Behavioral Therapy, Iran syringes. Unemployment (AOR= 1.1, CI: 95%, 0.01-1.2) and lifetime history of drug injection in prison were correlates of HCV (AOR= 2.9, CI: 95%, 1.2-7.4). Conclusion The study findings revealed the role of unemployment and imprisonment as two important risk factors associated with HCV seroincidence. HCV can be risky to the health of PWIDs especially co-injectors of heroin/high purity heroin with methamphetamine. Specific antiretroviral therapies should be tailored during implementing drug treatment and harm reduction services for PWIDS. HCV prevention and education are suggested in nationwide drug treatment programs. Keywords HCV Infection, Drug Injection, Methamphetamine, Heroin, Iran The Effectiveness of Cognitive-Behavioral Group Therapy on Sleep Quality of Drug-Addicted Subjects HCV Infection and Its Correlates among People Who Inject Drugs: Implications for Immediate Treatment Naser Sobhi1, Mohammad Ghaderi Rammazi2, Hamidreza Dehghan3, Mohammad Saleh Mohseni4 1. Associate Professor of Psychology Uneversity of Mohaghegh Ardabili 2. M.A. in General Psychology, Shahid Bahonar University of Kerman 3. Department of Psychology, University of Mohaghegh Ardabili, Ardabil Iran 4. M.A. in General Psychology, Shahid Bahonar University of Kerman Reza Daneshmand1, Zahra Alam Mehrjerdi2, Sara Shishegar3, Mehrnoush Bonakdar Tehrani4, Leila Arshad5 1. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 2. Program of International Research and Training, National Drug and Alcohol Research Centre, Faculty of Public Health & Community Medicine, University of New South Wales, Sydney, Australia 3. Centre of Cardiovascular Chronic Care, Faculty of Health, University of Technology, Sydney, Australia 4. Department of Public Health, Faculty of Public Health & Community Medicine, University of New South Wales, Sydney, Australia 5. Sarzamin e Khorshid Female-Specific Drop in Centre, Tehran, Iran Background and Aim Background and Aim One of the main routes of HCV transmission is drug injection. HCV infection has critical implications for health and should be specifically considered during drug treatment. The current study was conducted to identify the prevalence and correlates of HCV among people who inject drugs (PWIDs). Methods Participants were treatment seekers at seven drop in centres in the south of Tehran. During 2011-2012, 187 PWIDs were interviewed on the details of demographics, drug use, injection and high risk behaviours. Dried blood specimens were taken from participants. Logistic regression analysis was performed to find the relationships between the demographics, drug use, high risk behaviours and HCV status. Results The mean age of the sample was 35.8 years old. 67.2% were employed. 71.1% were married. PWIDs were heroin/high purity heroin injectors or co-injectors of heroin/high purity heroin with methamphetamine. 37.8% reported injecting methamphetamine in combination with heroin or high purity heroin within the past month. 26.6% were HCV positive. 20.1% reported lifetime shared The aim of present study was assessing the effectiveness of cognitive-behavioral group therapy on sleep quality of Drug-addicted subjects. Methods This study was experimental with a pre-test and pos-ttest design. The populations were all of the Drug-addicted individuals who referred to Kerman Air Force Base consulting center (summer of 2014). 30 male subjects based on simple accidental sampling Method selected as sample members. Subjects divided in two groups (15 Subjects as test group and 15 Subjects as control group). Test group members had eight 45-minute sessions over 8 weeks. For collecting data we used Pittsburgh Sleep Quality Index (PSQI) and for analyzing data we used Multivariate analysis of covariance (MANCOVA) method. Results The result showed that the cognitive- behavioral group therapy was effective on decreasing sleep disturbance, improving sleep efficiency, and improving of overall sleep quality of Drug-addicted subjects. Conclusion Because of overall increasing in the rate of sleep disorders in present age, and also critical role of sleep quality in mentally health of people, we need practical studies to find out the personally and environmentally factors that cause or cure sleep disorders. It’s obvious that sleep disorders are relating to many mental disorders. Since most of drug-addicted individuals complain of sleep disorders, improvement of their sleep quality could be a useful strategy for decreasing their mental problems and also stop- S20 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall ping of their reversion to drug usage after treatment. So based on the present study, cognitive-behavioral group therapy has positive and favorable consequences for sleep quality of Drug-addicted subjects. Keywords Cognitive-Behavioral Group Therapy, Sleep Quality, Drug-Addicted The Comparison of Degree of Commitment, Controllability, and Challengeability in Users of Narcotic Substances and Normal People at Sanandaj City Robabeh Delazar , Seyyed Ali Moosavi , Akram Shahmaleki , Hassan Farrahi4, Rezvan Abbasi5 1. Department of Psychology, University of Guilan 2. Research Center of Behavioral Sciences, Farabi Hospital, Kermanshah University of Medical Sciences 3. Kermanshah University of Medical Sciences 4. Department of Psychiatry, Guilan university of Medical Sciences 5. Kermanshah University of Medical Sciences 1 2 3 Background and Aim Stress is unavoidable fact of modern life that if was not inhibited and managed, can leads to low level of mental health and disposition to various mental disorders, particularly substances abuse. Psychological hardiness is one of effective mechanisms in coping with stress that play important role in reduction of substances use. Given a few researchs done in this case, the present research aims the comparison of degree of commitment, controllability, and challengeability in users of narcotic substances and normal individuals at Sanandaj city. Methods This research is an analytic cross-sectional study. The statistical population included all of male addicts at Sanandaj city that were under treatment in centers of curing addiction dependent to Wellbeing Organization. The research sample included demographically matched 230 male (115 users and 115 normal individuals). In order to assessing degree of degree of commitment, controllability, and challengeability, Kobasa Psychological Hardiness Inventory was used. After completing questionnaire, the gathered data was analysed by Spss-18 and independent groups T-test. Robabeh Delazar1, Seyyed Ali Moosavi 2, Somayyeh Sadri 3, Hassan Farrahi4, Rezvan Abbasi5 1. Department of Psychology, University of Guilan 2. Research Center of Behavioral Sciences, Farabi Hospital, Kermanshah University of Medical Sciences 3. Kermanshah University of Medical Sciences 4. Department of Psychiatry, Guilan University of Medical Sciences 5. Kermanshah University of Medical Sciences Background and Aim Cigarette is one of most addictive substances throughoutnworld. Many factors play role in tendency to smoking including various mental disorders such as anxiety and depression. Social support has significant effect on reduction of mental disorders and smoking. Methods The present research is an analytic cross-sectional study. The statistical population included all of smoking people at Kermanshah, and seventy five smoking individuals was selected randomly from houses, public places, neighbourhoods and parks in Kermanshah. In order to assessing friends social support, Multidimensional Scale of Perceived Social Support (MSPSS) was used, and degree of anxiety and depression was evaluated by DASS-42 quastionnaire. The gathered data was analysed by SPSS-18 softwar and Pearson correlation coefficient test. Results The analysis of data showed that friends social support has significant negative correlation with anxiety (r=0/333 , P=0/005) and depression (r=0/333 , P=0/005) in smoking individuals. Conclusion Given the obtained findings, there are negative relationship between friends social support and anxiety and depression of smoking individuals. So, it is necessary that relevant responsible people and therapists pay attention to social support resources in reduction of anxiety and depression of smoking people. Keywords Social Support, Anxiety, Depression, Smoking Results The findings showed that there are significant differences between degree of commitment (t=4/362 , P=0/000) and degree of controllability (t=3/744 , P=0/045) of addict and normal individuals, but such significant difference was not observed in case of degree of challengeability. Conclusion Given above-mentioned findings, this is concluded that because of significant differences between degree of commitment and controllability of addict and normal people,relevant therapists and responsible persons must pay attention to this problem and do necessary attempts in order to increasing coping strategies with stress. Keywords The Relationship between Degree of Friends Social Support and Degree of Anxiety and Depression of Smoking People Commitment, Controllability, Challengeability, Substance abuse Interaction of Addiction and Divorce and its Consequences Helaleh Delsouz khaki1, Seyed Mousa Kafi2, Hosein Aghababaei3 1. Department of Criminal Law and Criminology Science and Research Branch, Islamic Azad University, Guilan, Iran 2. Department of General Psychology, Feculty of Literature and Humanities, University of Guilan, Guilan, Iran 3. Department of Law, Feculty of Literature and Humanities, University of Guilan, Guilan, Iran Background and Aim With a realistic look at the issue of addiction as a dependency to harmful to the person, family and community, we find out there was this problem in the past and now there is almost no country which is safe against the spread of the problem. Drug abuse is one Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S21 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall of the most serious obstacles to the development of communities. According to the Iran’s geographic- economic position, it is in the neighborhood of the largest producer of opium and somewhat heroin, and the main pathway drug to Europe as well as the market for abuse. This caused Physical and epidemic trauma, such as HIV،hepatitis and even mental illness, in addition Increasing of drug-related crimes ، theft، murder، self-burning،unemployment، domestic violence ،spouse Abuse، child abuse and divorce، academic downfall about students whose parents are addicted. Nowadays, divorce is a major threat against the foundation of the family so recognition of effective and affected Factors is one of the mental health priorities. The mental health of generations depends on the mental health of family as a center full of love and peace for talent growth that any hurt will trace on the future generation. Divorce rates in a society can be considered as a result of instability and social insecurity and whereof it is the disruptive and disintegrated factor of the family, perforce the social consequences should be expected. In criminologists and social pathologist’s opinion, divorce isn’t ineffectual in the malefaction occurrence also it is effective on offense therefore the source of social pathologies as deviation،suicide،escape of home ،theft،addiction،beggary،tramp and etc. The Study is in order to survey the reasons of divorce requesting by women have decided to divorce and the role of addiction in divorce occurrence. Methods This study’s method is descriptive, data gathering tools are Interviews and questionnaire, the society of statistics is included of hundred women whom referred from the Family court to legal medicine center of guilan in order to pregnancy test before divorce. Results In this study, within one hundred samples, the reason of thirtyone divorce request was declared as addiction which this indicate that in thirty-one percent of samples, the addiction was effective on divorce occurrence and it was one of the divorce request and disintegration of families ‘s reasons. Conclusion The results showed there is a relationship between addiction and divorce and these two are effective and affected reciprocally so there is interaction between them. Keywords Addiction, Divorce, Family Comparison of Internalizing Disorders in 8-14-Year-Old Offspring of Opium and Heroin Dependent Parents: A Case-Control Study Mahin Eslami Shahrbabaki1, Hassan Ziaaddini2, Hamdollah Saieedi Gargari3, Nozar Nakhaee4, Parisa Divsalar5, Parvin Eslami Shahrbabaki6, Nasrin Eslami Shahrbabaki7 1. School of Medicine, Kerman University of Medical Sciences, Kerman, Iran 2. School of Medicine, Kerman University of Medical Sciences, Kerman, Iran 3. School of Medicine, Kerman University of Medical Sciences, Kerman, Iran 4. School of Medicine, Kerman University of Medical Sciences, Kerman, Iran 5. Department of Education, Bam University of Medical Sciences,Bam, Iran. 6. Nutrition, Ministry of Health and Medical Education, Tehran, Iran 7. Teacher, Kerman, Iran Background and Aim In general, parental substance abuse is associated with children’s emotional and behavioral problems. This study only investigated the internalizing problems (depression, anxiety and physical complains) in children of opioid or heroin-dependent parents in comparison with non-opioid dependent parents in order to determine the effects of drug dependency after excluding the confounding factors. Methods This case-control study compared the internalizing problems of one hundred twenty eight 8 to 14-year-old students in two offspring groups of opioid or heroin-dependent parents (n=64) and non opioid dependent parents (n=64). Then we used the Child Behavior Checklist (CBCL). Parents in both groups had no major psychiatric disorders (e.g., personality disorders, mood and anxiety disorders or psychosis), no history of major medical diseases, and no history of divorce. Analysis was performed using chi square or Fisher’s exact test. Results The anxiety/depression subscales in children of non opioid dependent parents were significantly higher in comparison with children of opioid or heroin-dependent parents. Conclusion Substance dependence in addition to reducing parental supervision on children may cause lack of knowledge and unawareness of their children’s anxiety and mood problems. Considering study limitations, study repetition in larger statistical population is necessary for generalizing the study findings. In order to assess internalizing problems in further studies, usage of behavioral checklists for self-report of children and youth is recommended. Keywords Internalizing Problem, Child Behavior Checklist (CBCL), Opium, Heroin, Opioid Comparission of Self Efficacy ,Self Regulation and Procrastination in Addicted Persons under Treatment with Methadone Maintanance Therapy,Therapeutic Community and Residental Treatment in Isfahan Ali Akbar Ebrahimi 1, Saeed Sadeghi2 1. Ph.D. Student in Psychology of Children with Special Needs, Isfahan Welfare Organization, Isfahan, Iran 2. PhD of Psychology, Isfahan Welfare Organization, Isfahan, Iran Background and Aim This study aimed to comparission of self efficacy ,self regulation and procrastination in addicted persons under treatment with methadone maintanance therapy,therapeutic community and residental treatment in Isfahan. Methods To achieve the above mentioned objective,180 addicted persons(each group 60 persons) were selected through random S22 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall sampling. Research method was ex post facto and the test used in this study was the ‘Self Efficacy ,Self Regulation and Procrastination’ quastionare. Data were analyzed by Analysis of Multivariate Covariance. Results According to the results, there were significant differences between the groups in terms of the variables and self efficacy and self regulation in therapeutic community are more than other groups. Procrastination in methadone group is higher than the other groups. Conclusion The overall results of the study showed the therapeutic community improve of self-efficacy, self-regulation and is an effective treatment methode for drug abusers. nity improve of a stress coping and support strategies and is an effective treatment methode for drug abusers. Keywords Methadone Maintanance Therapy,Therapeutic Community,Residental Treatment, Stress coping strategies,Support strategies Study on Factors and Barriers Affect for Womens Participation in Drug Abuse Prevention Aliakbar Ebrahimi1, Bita Agahi2, Hassan Asadi3 1. Ph.D. Student in Psychology of Children with Special Needs, Isfahan Welfare Organization, Isfahan, Iran 2. M.Sc. of Psychology, Isfahan Welfare Organization, Isfahan, Iran 3. Iran State Welfare Organization Background and Aim Keywords Methadone Maintanance Therapy,Therapeutic Community,Residental Treatment,Self Efficacy,Self Regulation,Procrastination. Comparission of Stress Coping and Support Strategies in Addicted Persons under Treatment with Methadone Maintanance Therapy,Therapeutic Community and Residental Treatment in Isfahan Ali Akbar Ebrahimi 1, Amir Ghamarani 2, Asye Ebrahimi3 1. PhD. Student in Psychology of Children with Special Needs, Isfahan Welfare Organization, Isfahan, Iran 2. PhD of Psychology, Educational Science and Psychology Faculty, University of Isfahan, HezarJarib St. , Azadi Sq. , Isfahan, Iran. 3. M.Sc. of Psychology, Educational Science and Psychology Faculty,University of Allameh Tabatabaee, Tehran, Iran. Background and Aim This study aimed to comparission of stress coping and support strategies in addicted persons under treatment with methadone maintanance therapy,therapeutic community and residental treatment in Isfahan Methods To achieve the above mentioned objective,180 addicted persons(each group 60 persons) were selected through random sampling. Research method was ex post facto and the test used in this study was the ‘stress coping and support strategies’ quastionare. Data were analyzed by Analysis of Multivariate Covariance. Results According to the results, there were significant differences between the groups in terms of the variables and support and proactive,intellectual strategic planning and preventive strategies in therapeutic community are more than other groups Conclusion The overall results of the study showed the therapeutic commu- Increasing drug abuse is social problem that more people know its threats and pathology. womens as one of basic factors in ever society can have effective role in drug abuse prevention.The goal of this research is study of Isfahan womens rate participation in four environments: home, local,community and society Methods Research method was survey and sample was selected by cluster random sampeling in 8 region and 409 family selected and administrated participation questionare that has 55 items.Reliability of questionare was /75.Data analyze by Spss. Results Womens participation in drug abuse prevention is very low , and order rate of participation is more in home,school,community and society.More participation is encouragement of recreational and cultural activities and second present in drug abuse prevention session.The most important action that effect for womens participation is Appreciation of active peoples and give information to people and finance and legal support of theirs. The most greatest barrier of womens participation on drug abuse prevention is Lack of motivation, lack of information and feare of damaged by drug Trafficers. Conclusion Womens participation in drug abuse prevention is very low and These findings can used for Developing community based drug abuse prevention program and Preparation of educational resources for increasing womens participation. Keywords Participation, Prevention, Drug Abuse The Effectiveness of Nonpharmacological Treatment on Continuance Methadone Maintenance Therapy Eshaq Ebrahimi1, Eshaq Ebrahimi(MA)2, Sadrollah Khosravi(Phd)3, Masoumeh Hamidi(MAs)4, Ali Reza Rahimi(MA)5, Tayebeh Shahrivar(MA)6 1. Assistance Correcting and Training of Fars Prisons Organization, Shiraz, Iran. 2. Assistance Correcting and Training of Fars Prisons Organization, Shiraz, Iran. Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S23 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall 3. Assistant Professor, Dep. of Psychology, FiroozAbad Branch, Islamic Azad University, FiroozAbad, Iran. 4. Dep. of Psychology ,College of Humanity Science,Yasouj,Sciense and Research Branch ,Islamic Azad University,Yasouj,Iran 5. Dep. Of Psychology,Fars Science and Research Branch, Islamic Azad University Marvdasht,Iran. 6. Dep. Of Psychology,Fars Science and Research Branch, Islamic Azad University Marvdasht,Iran. Background and Aim This study examined the effects of Behavioral Drug and HIV Risk Counseling on Methadone Maintenance Treatment(MMT) of addicts. Methods Participants included 30 Iranian addicts(equal samole size from each group) whose age ranged 18 to 65 years. Subjects of the study substitute in two test and control groups by simple random. Addicts individuals in Shiraz, were randomly assigned to Standard Services MMT(physician administered advice and support, and weekly urine test) and BDRC Services(guided behavioral drug and HIV risk reduction counseling(BDRC), and weekly urine test. They were under treatment for 20 sessions. ISAP questionnaire was used for collection of data and it was completed by chosen sample before and after experimental intervention. Regarding the loss in present study, the results were analyzed by SPSS and analytical chi Quare test and kolmogrov-smirnov test. Results The results of the study showed a significant difference in BDRC treatment of test group(p<0.0001). Outcomes included retention, proportion of opioid-negative urine tests, self reported drug use, and self reported HIV risk behaviors. The proportin of opioid- negative urine tests increased over time for both groups, and the reductions were significantly greater in the BDRC Services group(p<0.0001), Both groups reduced HIV risk behaviors during treatment but the difference between BDRC and Standard Services(80% vs. 26.7%) was statistically significant. Conclusion Also, the results showed the effectiveness of Behavioral Drug ang HIV Risk Counseling on Methadone Maintenance Treatment(MMT). The hypothesis of the study were supported. Keywords Methadone Maintenance, Drug addiction The Effectiveness of Mindfulness based Cognitive Therapy in Group in Reducing Depression, Anxiety, and Relapse Prevention in Drug-Dependents Hossein Eghbali1, Arva Bakhtiari2, Mahdi Zare3, Vahid Ahmadi4 1. Department of Clinical Psychology, Islamic Azad University, Qom Branch 2. Department of Clinical Psychology, Islamic Azad University, Qom Branch 3. Center for Research and Development in Humanities, SAMT organization 4. Department of Psychology, Payam Noor University, Ilam Branch Background and Aim In recent years the use of methadone for drug abuse treatment has been improved. However, the research and application of non-pharmacological treatments in methadone treatment requires more attention and the use of new psychological treatments can offer an adequate model in the treatment of drug dependence. To evaluate the efficacy of mindfulness based cognitive therapy in group in reducing depression, anxiety, and prevention of relapse in drug-dependent individuals, was the main objective of this study. Methods In a quasi-experimental design, 24 male patients with a diagnosis of drug dependence based upon DSM IV-TR were put randomly in two groups of experiment and control. Participants using Beck depression (BDI) and Anxiety (BAI) questionnaire at the beginning of the study, after the end of treatment and after three months post-treatment follow-up phase were evaluated. The control group received no treatment, and only took methadone. Data with analysis of covariance, chi-square and analysis of variance with repeated measures were examined. Results The results showed that the mindful-based cognitive therapy has effect on: reducing relapse (P < 0.05), increasing the length of remaining in treatment (P < 0.01), increasing compliance, reducing anxiety and depression (P < 0.01). Conclusion It seems that mindfulness based cognitive therapy in group, while increasing the effect of methadone treatment, and reducing emotional problems, also is effective on relapse prevention. Keywords Mindfulness-Based Cognitive Therapy, Anxiety, Depression and Relapse The Effectiveness of Group Motivational Interview in Decreasing Relapse and Increasing Self-Efficacy and Improving Methadone Treatment Hossein Eghbali1, Arva Bakhtiari2, Hamid Poorsharifi3, Vahid Ahmadi4 1. Department of Clinical Psychology, Islamic Azad University, Qom Branch 2. Department of Clinical Psychology, Islamic Azad University, Qom Branch 3. Department of Psychology, Tabriz University 4. Department of Psychology, Payam Noor University, Ilam Branch Background and Aim To evaluate the effectiveness of group motivational interview in relapse prevention and improving methadone treatment was the main goal of this research. Methods In a semi-experimental design, 24 male patients with diagnosis of substance dependence according to DSM-V were substituted in two experimental and control groups randomly. Participants were evaluated by Beck Anxiety Inventory (BAI), Beck Depression Inventory(BDI)and the Anger Questionnaire (AQ), at the beginning of the study, after the treatment period and in the follow-up phase ( three months after the end of treatment). Control group with no psychological treatment only took methadone. Data were analyzed using covariance analysis, chi square and Repeated S24 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Measures Analysis of Variance. Results Results showed that the effect of matrix group interventions on reducing relapse (p < 0.05 ), increasing the maintenance of treatment (p < 0.01) , increase treatment compliance, reduce anxiety, depression, anger and methadone use is more effective than methadone treatment (01/0 P <). Conclusion It seems matrix group interventions increase the effectiveness of drug treatment with reduction of relapse prevention , emotional problems and the dose of methadone . Keywords Matrix Interventions, Anxiety, Depression, Aggression, Daily using of Methadone and Relapse. Relationship Between Self-Conscious Affect, Impulsiveness and Problem-Oriented Strategy in Drugs Drop-Out Volunteers Parvin Ehteshamzadeh1, Salem Hardanpoor2, Laleh Hamidi3, Farshad RaMezanzadeh4 1. Islamic Azad University, Branch Ahvaz, Iran, Assistant Professor in General Psychology 2. Islamic Azad University, Ahvaz branch, MA. Educated in General Psychology 3. Islamic Azad University, Ahvaz branch, Iran, MA. in General Psychology 4. Islamic Azad University, Ahvaz branch, College Student in Clinical Psychology Background and Aim The purpose of this study was to investigate the relationship among self-conscious affect, impulsiveness and problem oriented coping strategy. Methods The research sample consisted 73 male volunteers of drugs dropout, that were selected by randomly throught cluster sampling from between twenty- seven camp of voluntary for drugs dropout in Ahvaz city in Iran. Participants completed self-conscious affect questionaire(TOSCA-3) consisted senses of sham, guilt, externalization,detachment, alfa pride and beta pride, Barrett Impulsiveness scale, and problem oriented subscale of Belings and Moos coping strategies. Statistic methods of research were descriptive statistics, Pearson correlation coefficient and multiple regression. Results The results showed that there were significant and negative correlations between problem oriented strategy and sham, and between problem oriented strategy and impulsiveness. There was significant and positive correlation between guilt and problem oriented strategy. Finding suggessted that there was multiple correlation among sham, guilt and impulsiveness with problem oriented strategy, and the first order impulsiveness(p<0/001), and then guilt(p<0/02) were the most predictive variables for use of problem oriented strategy. Conclusion Personality variables can be important for understanding substance abuse. This can help to choose strategies for training skills for management impulsiveness, which is predisposing factor to sub stance abuse.So, this study indicate that sense of guilt can be motivational factor that lea ding to use of problem oriented strategy and result in attempt for drugs drop- out in addicts. Keywords Self Conscious ,Impulsiveness, Problem Oriented Strategy, Drugs Drope-Out Substance Abuse and the Risk of Fatal Traffic Accident Crash Injuries Monir Seyedsalehi1, Mohammadali Emamhadi2 1. Head of Social Worker Department, Shahid Beheshti University of Medical Sciences, Tehran, Iran 2. Associated Professor of Forensic Medicine and Toxicology, Head of Forensic Medicine and Toxicology Department, 7Tir Trauma Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran Background and Aim Traffic accidents, which have high mortality and morbidity, are an important public health problem. It’s well known that humanity factors are the most important causes in traffic accident. Methods By using a case-control design, we assessed the association between substance abuse and fatal traffic accident injuries in “7tir trauma center”, Tehran, Iran during specific time periods in 20123. Cases (n=737) were drivers who were involved in fatal motor vehicle crashes and controls (n=750) involved in mild accident injuries. Urine and/or blood samples were collected on admission for drug detection. Results Overall, 26.9% of the cases and 9.7% of the controls tested positive for at least one drug. The estimated odds ratios of fatal crash injuries associated with specific drug categories were 2.03 [95% confidence interval (CI): 1.62, 2.92] for narcotics, 3.11 (95% CI: 2.42, 4.71) for alcohol, 3.91 (95% CI: 3.02, 4.55) for amphetamine. Cases that tested positive for both alcohol and amphetamine were at increased risk relative to those were clear (Odds Ratio=29.31; 95% CI: 18.71, 35.62). Conclusion This study shows that drug abuse, especially amphetamine in combination with alcohol, is associated with a significantly increased risk of fatal crash injuries. Keywords Humanity Factors, Substance Abuse, Traffic Accidents Evaluation of the Methods in Decreasing the Students’ Dependency on Smoking Maryam Jalilvand 1, Mohammadali Emamhadi2 1. Tohid Counseling and Psychological Services, Ministry of Education and Training, Tehran, Iran 2. Associated Professor of Forensic Medicine and Toxicology, Head of Forensic Medicine and Toxicology Department, Shahid Beheshti University of Medical Sciences, Tehran, Iran Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S25 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Background and Aim Smoking is the major health problem between juvenile nowadays and is the first cause of preventable morbidity and mortality in the world. The aim of this study is the evaluation of different methods in reduction of the smoking dependency in students Methods This semi-experimental study comprised all 7th grade students studying in middle schools throughout Iran in the year 2012-2013. Students were divided into 4 groups: three study groups (social skills training, increasing knowledge and poster presentation) and 1 control group. Sampling method used was multi-phase cluster. The country was geographically divided into 5 districts (north, south, east, west and central) and the provinces were selected randomly. A questionnaire was used to collect the data. These questionnaires were designed to evaluate the attitude and knowledge of students with regard to smoking and complications. Results A total of 3012 students with the mean age of 13 years were studied out of which 15.8% were smokers. There were significant differences between the study groups and the control group regarding the attitude and knowledge about the hazards of smoking and abuse of illicit substances. In other words, among the study groups, social skills training, building knowledge and poster presentation had the best results, respectively. Conclusion In evaluating the preventive methods, social skills training group had the most negative attitude and the highest level of knowledge concerning the disadvantages and hazards of smoking and use of illegal substances. The greatest decrease in smoking was also observed in this group. Social skills training can be an effective preventive measure to control smoking by emphasizing self-respect, problem-solving skills and self restraint Keywords Attitude, Prevention, Smoking Tendency, Social Skills, Training Addiction & Prediction Maryam Emamizadeh1, Hossein Aghajani Mersa2 1. MA of Anthropology Science And Research Branch of Islamic Azad University of Tehran 2. Faculty Member of Azad University Background and Aim Addiction is one of problem in human society which is known as a biological psychological and social disease, we can see it around us seriously. Arising problems in families, society and increasing the amount of crime in the society, indicate the need for attention to this issue and also lack of attention to this social problem, lack of serious studying and pathological addiction , lack of cohesive and comprehensive plan all are as factors which led to growing addiction in the society. Since dealing with addiction problems requires substantial time and cost so prevention is much more effective rather than treatment and the most effective way for a health society is preventing the proliferation and drug distribution which is required to much more attention from responsible. General aim of this study is identifying effective ways in order to reducing ad- diction and prevention before treatment. Methods In this study both quality and quantity methods are combined and needed information by using of questionnaire technique is collected and statistical population is composed of 40 peoples who are addicted and 20 people as experts of prevention offices in 10 region of Tehran are selected. Results It shows that all plans which are applied in order to prevention are as total Maximum agreements among responders who considered to community-based plans (64%) and after that other responses considered to comprehensive and focused plans based on giving information and awareness. Among aimed groups , people who have more influence on addicted and can prevent them are parents (75%) then friends (54%) which are really important and most of the responders are believed that among four prevention methods , it is better that needed budgets would be assigned to the hedging. Conclusion Keywords Addiction, Prevention, Drug Abuse, Cultural Poverty, Ten Region of Tehran Comparison of Physical Complaint of Substance Abusers Wives and Normal Person Considering Mediator Role of Social Support in MMT Center Client (1391) Abdolhakim Tirgari1, Babollah Bakhshipour2, Roshanak Eskandari Rad 3, Seyed Hamzeh Hosseini4, Hamid Reza Eskandari Rad5 1. Behavioral Science and Psychiatric Research Centre , Zare Psychiatric Hospital, Mazandaran University of Medical Sciences , Sari , Iran 2. Department of Counselling, Payam-e-Noor University, Sari, Iran 3. Faculty of Psychology , Payam Noor University, Behshahr , Iran 4. Behavioral Science and Psychiatric Research Centre, Zare Psychiatric Hospital, Mazandaran University of Medical Sciences, Sari , Iran 5. Faculty of Psychology and Educational Sciences, Islamic Azad University, Sari , Iran Background and Aim Addiction is a chronic and progressive disease, with social, psychological, physical profound implications and it can disturb the wife emotional and personality balance in family . thus , the purpose of present study is Comparison of physical complaint of substance abusers wives and normal person considering mediator role of social support in MMT center client . Methods this study is descriptive ,case - control study. The statistical population of case group includes all of substance abusers wives that have record in Behshahr MMT center ( 1391) . The statistical population of control group includes all of normal person wives in Behshahr that matched with case group after study and giving demographic information (age , sex , education) . The sample in case group consisted of 150 substance abusers wives . The sample in control group consisted of 150 normal person wives that selected by available sampling .To collect the data , disease S26 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall severity rating scale shokrkon , wax Social support questionnaire were used. For data analysis independent t test and Spss-16 software were used. Results This study show that there are significant relationship between physical complaint in substance abusers wives and normal person wives(p=0/05) . also , social support can predict physical health in normal person wives (determination coefficient= 0/04 ). Conclusion The results of this study show social support can predict physical health in normal person wives Keywords Social Support, Physical Complaint, Substance Abusers Wives and Normal. National Harm Reduction Program by Methadone Maintenance Treatment Sharareh Eskandarieh 1, Ali Nikfarjam 2, Termeh Tarjoman3, Abassali Nasehi4, Firoozeh Jafari 5, Mohammad-Bagher Saberi-Zafarg-Handi6 1. Bureau of Mental & Social Health and Addiction, Ministry of Health, Treatment and Medical Education, Tehran, Iran 2. Bureau of Mental & Social Health and Addiction, Ministry of Health, Treatment and Medical Education, Tehran, Iran 3. Bureau of Mental & Social Health and Addiction, Ministry of Health, Treatment and Medical Education, Tehran, Iran 4. Bureau of Mental & Social Health and Addiction, Ministry of Health, Treatment and Medical Education, Tehran, Iran 5. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 6. Mental Health Research Center, Tehran Institute of Psychiatry- school of Behavioral Sciences and Mental Health, Conclusion Descriptive aspects of demographic and behavior characteristics among IDUs who took part in MMT program was addressed in this study. World experience has shown that rapidly starting a comprehensive program comprised of extensive psycho-education, needle exchange and low thre-shold maintenance treatment will effectively blunt and limit HIV epidemics in countries with similar drug scenes (37). In addition, participating in MMT has been shown to reduce the risk of acquiring blood-borne infection in communities experiencing high rates of transmission We conclude with some suggestions for action: (1) Prevention programs including harm reduction programs, treatment programs, and counseling centers should include young IDUs as a core focus of their intervention structure; (2) Funding of such programs should be increased. Keywords IDUs, Harm Reduction, Methadone Maintenance Treatment, Iran The Feasibility of Computer-Assisted Survey Interviewing in Iran Nayereh Esmaeilzadeh1, Seyed Abbas Motevalian2, Kazem Mohammad3, Hamid Reza Fathi4 1. MSc, Department of Epidemiology and Biostatistics, Mashhad University of Medical Sciences, Mashhad, Iran 2. Associate Professor, Department of Epidemiology and Biostatistics, School of Public Health, Iran University of Medical Sciences, Tehran, Iran. 3. Professor, Department of Epidemiology and Biostatistics, School of Public Health,Tehran University of Medical Sciences, Tehran, Iran 4. PhD Student,School of Advanced Medical Technologies,Tehran University of Medical Sciences, Tehran, Iran Background and Aim Background and Aim The Ministry of Health, Treatment and Medical Education of Iran has recently announced an estimated figure of 200,000 injecting drug users (IDUs). The aim of this study was to pilot a national program using demographics, types of drug abuse and prevalence of blood-borne infections among IDUs. The objective of this study was to describe the demographics, types of drug abuse, and prevalence of blood-borne infections among IDUs in Tehran. Methods In order to elicit data on demographics, types of drug abuse and prevalence of blood-borne infections among IDUs, a questionnaire was designed in the Bureau of Mental-Social Health and Addiction in collaboration with Iran’s Drug Control Headquarters of the Police Department. Therapeutical alliance of addiction in Shafagh Center was based on Methadone Maintenance Therapy (MMT).The research team included 4 physicians, 4 psychiatrics, 3 nurses, 3 social work-ers, and one clinical psychologist who had the re-sponsibility of treating and training the drug ab-users. Results 65.9% and 18.8% for HCV and HIV/AIDS infections, respectively. Among 402 reported IDUs most of them were male, single and in age range of 20 to 39 years old with 72.7% history of imprisonment. Most of them had elementary and high school education and a history of addiction treatment. The majority were current users of opioid, heroin and crack. The prevalence of blood-borne infections was This study was preliminary study testing a new technology for survey data collection: computer-assisted self interviewing(CASI). This technology has the theoretical potential of providing privacy (or anonymity) of response equivalent to that of paper self-administered questionnaires (SAQs). In addition, it could offer the advantages such as the ability to implement complex questionnaire logic, consistency checking, etc. we assessed the feasibility of using CASI and evaluating whether CASI can improve the reporting rate of substance use compared with traditional methods of interviewing, paper-and-pencil interviewing (PAPI) and face to face interview(FTFI), in a household survey of adults in two region of Khorasan Razavi. Methods We used multistage cluster sampling of 571 adults aged 18-64 years in kalat town and mashhad city. the adults were assigned to one of the three interview methods. half of adults were randomly assigned to CASI (n _ 287) and other half to PAPI and FTFI (n _ 284). the study was performed with validated questionnaire of drug problems and a customized CASI program was developed. We also considered the results of observations and records of interviewers in fieldwork. Results The CASI technology performed relatively well during fieldwork, Few problems arose with the CASI software or computer Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S27 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall hardware; the source of most problems derived from the programming and disconnecting the interview. The highest response rate and lowest non response item related to Computer Assisted Self Interview p <0.05. The adult easily adapted to the computerized interview and were able to complete the survey, but they needed more assistance from the interviewing staff than FTFI. The mean time to complete the survey was shorter in FTFI than others and CASI had moderate time to complete. For readily available substances, the lifetime, years and month time prevalence were no different between methods for cigarettes and tobacco use. For illicit drug use, the lifetime prevalence for opium no different between method. Years and month time the PAPI group was significantly higher for the use of opium. other illicit drugs were reported rarely and no different were between methods. In multiple logistic regression analysis, the differences between the method in the use of opium in year and month time, remained significant. confront the drug problem” the scores was: 0.012, 0.009, 0.021, 0.045, 0.037, 0.053, 0.001 respectively. Conclusion In an overview, harm reduction measures been implemented under methadone for prisoners to improve their areas of life was effective instrument that can be done and greater things, decreasing the incidence of disease risk was in prison and the community. Keywords Harm Reduction, Methadone, Areas of Life, Prison, Tehran The Study of Effectiveness of Life Skills Teachings on Attitude Change towards Drugs among Conscripts in Tehran Prisons Iraj Esmaili1 1. Research Manager of Tehran Prisons HQ Conclusion However CASI had the highest response rate and item but the finding related to Substance were Unexpected. also the high startup costs of equipment and the technical difficulties of field research were doubtful to use CASI. Yet Its seem if costs of hardware decline and the availability of high-quality survey software increases, computer-assisted surveys will likely become useful Keywords Household Survey, Computer Assisted Self Interview, Paper And Pencil Self Interview, Face To Face Interview, Substance Evaluation of Areas of Life under Prisoner’s Coverage in Tehran Prisons: Effect of Methadone Maintenance Treatment in 2013 Iraj Esmaili1 1. Research Manager of Tehran Prisons HQ Background and Aim Survey of acts to have been taken in prison such as harm reduction and Monitoring of health condition in prison population is very important for return the safe force labor to community and prevention of health potential problems. Methods This type of research has been applied studies that the two phases and length of follow events in 2009 were achieved. The data collection questionnaire for demographic information and areas of life validated checklist was used. Statistical analysis of data collected using the software SPSS (xp) XIII and descriptive statistics was performed. Results After six months in total, 250 people were responsive to 27 (10.8%) in Evin Prison, 135 patients (54.0%) Qezelhesar in prison and 88 patients (35.2%) in prison are in the Rajaee Shahr. Decuple areas studied in areas of life, such as: “the use of services and programs to reduce losses,” “Roads of legal problems”, “improved family relations,” “ways to improve”, “roads inhibit negative feelings”, “ways of coping with health problems “, and” ways to Background and Aim Since in countries like Iran where drug abuse rate is high ،this can be troublesome in working environments and barracks. Thus this study aimed to assess the effectiveness of life skills teachings on attitude change towards drugs among conscripts in Tehran prisons 2012. Methods According to the objectives data collection method ،this study is both practical and experimental in which there is a case group and two control groups. A demographic questionnaire and Attitude assessing checklist containg 10 dimention were used in this study. Results The selected conscripts were put in three groups: training group (65) ،inner control group (64) and outer control group (67). After ten session of training and based on the findings ،the comparison of the three groups indicated the following Results General attitude towards addiction (p-value =0.001). Attitude towards drugs (p-value =0.001). Attitude towards drug abuse reason (p-value =0.001). Attitude towards the personality of the addict person (pvalue =0.004). Public attitude towards addiction (p-value =0.001). Attitude towards detoxification (p-value =0.001). Attitude towards escape from addiction (p-value =0.011). Attitude towards addiction as a solution in life (p-value =0.007) has been changed and it is statistically significant. Conclusion According to the results of the present study ،intervention and teaching life skills affects the conscripts attitude ،and can play important role in reducing drug abuse in the society. Keywords Prevention, Drugs, Conscripts, Life Skills S28 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Administration of Venlafaxine after Methadone Detoxification Reduces Spontaneous Freezing Withdrawal Behavior in Rats: Positive Correlation with Hyperalgesia Meisam Fadaei kenarsary1, Yaghoob Farbood2, Seyed Mohammad Taghi Mansouri3, Hadi Fathi Moghaddam4 1. Department of Physiology and Physiology Research Centre, School of Medicine, Ahvaz Jundishapur University of Medical Sciences (AJUMS), Ahvaz, I.R. Iran 2. Department of Physiology and Physiology Research Centre, School of Medicine, Ahvaz Jundishapur University of Medical Sciences (AJUMS), Ahvaz, I.R. Iran 3. Department of Pharmacology and Physiology Research Centre, School of Medicine, Ahvaz Jundishapur University of Medical Sciences (AJUMS), Ahvaz, I.R. Iran 4. Department of Physiology and Physiology Research Centre, School of Medicine, Ahvaz Jundishapur University of Medical Sciences (AJUMS), Ahvaz, I.R. Iran Background and Aim Methadone has been used as a drug to detoxify opioid tolerance. Naloxane-precipitated morphine withdrawal behaviors were attenuated by venlafaxine as an antidepressant. In contrary, after detoxifying the opioids, spontaneous withdrawal syndrome may be occurred with pain sensitivity. Therefore the present study aimed to examine the effects of chronic methadone (70 mg/kg, in drinking water, 7 days), venlafaxine (80 mg/kg/day, intraperitoneally, 7 days) and their sequential administrations on the spontaneous morphine withdrawal syndrome and pain sensitivity. Farbod Fadai1 1. Farbod Fadai, Department of psychiatry, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran. Background and Aim There are numerous debates and unanswered questions about the moral or criminal responsibilities in drug dependence. So, I decided to assess the various kinds of responsibilities in people with drug addiction Methods Reviewing the related resources in medicine, social sciences, law, and philosophy Results There are to main points of view emong the thinkers. A group believe in free will of human beings and regard addiction as a personal choice. another group think that addiction is beyond the ideal concept of free will and see the people with addiction as patients who need treatment Conclusion It seems that the truth lies beetween these two contradictory beliefs. Keywords Addiction, Responsibility, Illness Methods Twenty eight young male Sprague-Dawley rats were randomly divided into 4 groups: control, methadone treated, venlafaxine treated, and methadone + venlafaxine treated. Morphine sulfate (10 mg/kg/day, subcutaneously, 4 days) injected to all animals. Then primary behavioral and tail flick tests were performed. It followed by methadone or its vehicle administration. Second intervention was venlafaxine or its vehicle injection. Then final behavioral and tail flick tests were performed. Results Chronic methadone substitution followed by venlafaxine administration, reduced freezing behavior of spontaneous morphine withdrawal syndrome significantly (p<0.01, 379±144%). Chronic methadone administration induced hyperalgesia significantly (p<0.05, 35±8% difference with venlafaxine treated group). A positive correlation (p=0.001, +63%) was observed between the animal’s final freezing scores and response latencies to the painful stimulus. Conclusion Administration of venlafaxine after chronic methadone detoxification reduces spontaneous freezing withdrawal behavior. Further investigations on analgesic interventions are needed to overcome this hyperalgesia. Keywords Addiction: A choise or an Illness? Morphine Withdrawal Syndrome; Methadone; Venlafaxine; Pain; Rat Drug use in HIV Vulnerable Women Attending to “HIV Sexual Harm Reduction Centers” in Iran Noushin Fahimfar1, Abbas Sedaghat2, Kianoush Kamali3, Azam Valipour4, Maryam Sargolzaee Moghaddam5, Mohammad Mehdi Gouya6 1. AIDS Control Office, Center for Communicable Disease Control, Tehran,Iran 2. AIDS Control Office, Center for Communicable Disease Control, Tehran,Iran 3. AIDS Control Office, Center for Communicable Disease Control, Tehran,Iran 4. AIDS Control Office, Center for Communicable Disease Control, Tehran,Iran 5. AIDS Control Office, Center for Communicable Disease Control, Tehran,Iran 6. Center for Communicable Disease Control, Tehran,Iran Background and Aim Although HIV epidemic is in the concentrated phase among Injecting Drug Users (IDUs) in Iran, sexual transmission of HIV is increasing. Vulnerable women are assumed as important population for driving HIV epidemics. For response to this concern, “HIV Sexual Harm Reduction Centers” have been established in Iran as the first practice in the region to provide more specific facilities for HIV/AIDS vulnerable women. Having increased risk of receiving HIV through high risk sexual behavior put women in our target group. Some important services are routinely offered in these centers to prevent HIV/AIDS transmission. This study aimed to explain a number of main services provided for target population during last month. The results can help the governors to plan more comprehensive interventions. Methods The list of requested questions and activities were reported by Health Deputies of Medical Universities who are responsible to supervise these centers. Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S29 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Results There are 29 centers throughout the country at April 2014. In all, more than 6000 vulnerable women were registered in these centers. During April 2014, 2100 clients attended at least once in centers to get services; of them 50% had reported drug use besides high risk sexual behaviors. It should be highlighted that around 61% of these group reported the use of methamphetamines during this month. It means one third of all women attending to the centers during one month were met users. Near 45% of drug users have been under treatment of methadone. Totally, 1762 syringes, 38000 male condoms and 2500 female condoms were distributed in one month. In parallel, under supervision of the centers, outreach teams dispersed around 22000 condoms and 7500 syringes to 3500 HIV most at risk women. Counseling and training sessions were hold both individually and in groups. Around 30% of attending women were examined for Sexually Transmitted Infections during one month; of them 50% were candidate for treatment. scientiousness., In MMT group neuroticism, openness, agreeableness, conscientiousness, extraversion., in addict group neuroticism, extraversion, openness, agreeableness, conscientiousness., in non addict group agreeableness, extraversion, openness, conscientiousness, neuroticism. There was a significant difference in neuroticism between the MMT group with the addict group and the MMT group with the non addict group; with the addict group scoring higher in this trait (p<0.05). Conclusion Among personality traits, neuroticism has the highest power to predict treatment attempt and maintain in addicted patient. Keywords Addicted Patient, Personality Trait, Methadone Therapy, Narcotics Anonymous The Modern Role of fMRI in Drug Addiction Research Conclusion Vulnerable women may play important role in HIV epidemic. Concentrated epidemics, if neglected, have the potential to change into generalized epidemics. As results showed, there is strong overlap between high risk sexual behavior and drug use. The use of methamphetamine has been detected in most of the drug users. Regarding the treats of using methamphetamine and the effects of this drug on high risk sexual behavior, more comprehensive interventions seem to be necessary. These centers are good opportunity to access to these vulnerable women. Keywords HIV/AIDS, Vulnerable, Women, Iran, Methamphetamine Comparison of Personality Traits in Addicted Patient, Narcotics Anonymous (NA), Addicts Under Methadone Maintenance Therapy, and Non Addict Farideh Faraji1, Saied Jalil Hosseini2, Ahmad Sohrabi3, Farzin Rezaie4 1. Iran Drug Control Headquarters 2. M. A. of Clinical Psychology, Kurdistan University of Medical Sciences 3. Assistant Professor of Psychology, Kurdistan University 4. Assistant Professor of Psychiatry, Kurdistan University of Medical Sciences Background and Aim Current study conducted to identify personality traits in addicted patient, members of narcotics anonymous (NA), addicts under methadone maintenance therapy, and non addict as prediction factors of treatment attempting and maintaining. Methods This descriptive cross-sectional study performed on totally 144 drug abusers include 109 male addicted patient, members of narcotics anonymous (NA), addicts under methadone maintenance therapy and 35 male non addict. Data were gathered using the NEO Five-Factor Inventory- Revised (NEO-FFI-R). Data were analyzed using multi- factor analysis of variance and post hoc Tukey test. Results The highest personality traits In NA group respectively were include: openness, agreeableness, extraversion, neuroticism, con- Mohammad Hassan Farhadi1, Mohammad Taghi Joghataei2, Mohammad Ali Oghabian3, Hamed Ekhtiari4, Ali Farhoudian5 1. Institute for Cognitive Science Studies (ICSS), Tehran, Iran. 2. Department of Anatomy and Neuroscience, Cellular and Molecular Research Center, School of Medicine, Iran University of Medical Sciences, Tehran, Iran. 3. Research Center for Science and Technology in Medicine, Tehran University of Medical Sciences, Tehran, Iran. 4. Institute for Cognitive Science Studies (ICSS), Tehran, Iran. 5. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran Background and Aim Animal studies of reward processing have been an area of intense investigation for more than 60 years. These studies have identified numerous neural structures involved in reward processing and reward-dependent learning. Until recently, this work provided the primary basis for speculations about the neural substrates of human reward processing. The widespread use of neuroimaging technology has changed this situation dramatically over the past decade through the use of positron emission tomography (PET) and functional magnetic resonance imaging (fMRI). Since its development about 25 years ago, fMRI has become the leading research tool for mapping brain activity. The technique works by detecting the levels of oxygen in the blood, point by point, throughout the brain. Methods This paper review and introduces the basic principles and techniques of fMRI, and also focus on the role played by fMRI in drug addiction studies. Results In only a few years, fMRI has proven itself to be a powerful technique in the study of reward processing and has contributed to our understanding of the function of numerous reward-related brain structures. Recent work has replicated the animal results in human subjects and has extended the view of putative rewardprocessing neural structures. In particular, fMRI has identified a set of reward-related brain structures including the orbitofrontal cortex, amygdala, ventral striatum, and medial prefrontal cortex. Current experiments aim to assess the function of human rewardprocessing structures to determine how they allow us to predict, assess, and act in response to rewards. S30 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Conclusion These new findings may provide crucial insights into diseaserelated deficits and may contribute to improved treatments. Keywords Reward, fMRI, Striatum, Amygdala, Orbitofrontal Cortex, Brain Function Nurses’s Experiences of Concealment Consequences of Drug Dependence Patients in CCU: A Qualitative Study Sedigheh Farzi1, Saba Farzi 2, Jafar Moghadasi3, Mohammad Akbari Kaji4, Saied Foroughi 5, Azam Moladoust 6, Maryam Sohrabi7 1. PhD Student of Nursing, Isfahan University of Medical Sciences, Faculty of Nursing and Midwifery, Isfahan,Iran 2. MSc,Lorestan University of Medical Sciences,Lorestan,Iran 3. PhD Student of Nursing, Isfahan University of Medical Sciences, Faculty of Nursing and Midwifery, Isfahan,Iran, Faculty Member Sharekord University of Medical Sciences,Shahrkord ,Iran. 4. PhD Student of Nursing, Isfahan University of Medical Sciences, Faculty of Nursing and Midwifery, Isfahan,Iran. Member of Young Reserchers Club, Islamic Azad University Khoorasgan Branch, Khoorasgan, Isfahan , Iran 5. MSc: PhD Student of Nursing, Faculty Member Lorestan University of Medical Sciences, Lorestan ,Iran. 6. MSc:Isfahan University of Medical Sciences,Isfahan,Iran. 7. BSc, Mofid Hospital,Shahid beheshti University of Medical Sciences,Tehran,Iran Background and Aim Due to numerous problems of patient in cardiac care unite, nursing care of these patients are sensitive rather than patient in general ward. In addition, the patient’s underlying condition such as disease, allergies and drug dependence are instances that the nurses in the care of these patients should be considered.This study aimed to identify nurses’ experiences of concealing outcome of patients with drug dependence for proper management of care plan has been made. Methods A phenomenological qualitative approach was used. Participants in this study were nurses working in hospitals of Isfahan had experienced caring of patients with drug dependence in cardiac care unite. Purposive sampling was adopted in the study and sample size was dependent on the data saturation with a total 6 participants were chosen at the end. Data collection carried out through unstructured interviews and analysis through colaizzi method Results From the finding of this study, 100 primary code expressing participants experiences were emerged that forming the three secondary code: The negative attitude of the patient, interference in the process of care, patient dissatisfaction and finally composed theme Concealment consequences of patient. Conclusion Addiction one of the topics that today’s society has suffered and affected all aspects of society. Addict’s patient may be hospitalized because of illness in health care and nurses should provide complete care to them. Nurses’ experiences in the present study indicates that patients and their families concealed problem of drug dependence from team treatment, including nurses, therefore reduction of care programs and patient dissatisfaction was occurred. Therefore strategies must be taken into account at the beginning of the patient care that team treatment and caring become aware of their dependence to follow the care plan to suit their requirements and these patient receive complete care. Keywords Nurses’s Experiences, Concealment ‘s Outcomes, Addiction Patients Morphine-induced conditioned place Preference Increases Apoptotic Factors in Rat Prefrontal Cortex: Involvement of Physical Stress Zahra Fatahi1, Abbas Haghparast2, Fariba Khodagholi3 1. Neuroscience Research Center, Shahid Beheshti University of Medical Science, Tehran, Iran 2. Neuroscience Research Center, Shahid Beheshti University of Medical Science, Tehran, Iran 3. Neuroscience Research Center, Shahid Beheshti University of Medical Science, Tehran, Iran Background and Aim Prefrontal cortex (PFC) is one of the most important areas involved in the rewarding action of opiates such as morphine. It has shown that this area affect by different kinds of stress. Additionally, both morphine and stress can induce apoptosis in neural cells. In this study, we investigated the effects of morphine-induced conditioned place preference (CPP) in the presence and absence of stress on the changes in the apoptotic factors (Bax/Bcl-2 ratio, caspase-3 activation and PARP degradation) in the PFC. Methods Male Wistar rats were divided into two saline- and morphinetreated supergroups. Each supergroup consisted of control, acute stress (AS, received forced swim stress just one day) and subchronic stress (SS, received forced swim stress for three consecutive days) subgroups. In all groups, the CPP paradigm was performed; thereinafter the PFC was dissected out and the alterations of apoptotic factors were measured by western blot analysis. Results The results indicated that in the saline-treated animals, AS and SS significantly enhanced apoptotic factors (except for Bax/Bcl-2 ratio during AS). Similarly, in the morphine-treated animals, AS and SS increased apoptotic factors significantly (except for Bax/ Bcl-2 ratio during AS and SS). Conclusion Our findings suggested that in the saline- or morphine-treated animals, AS and SS enhanced the apoptotic factors in the PFC and this increase in the morphine-treated animals was more considerable than that in the saline-treated animals. In other words, stress potentiated the effect of morphine-CPP on the increase of apoptotic events. Keywords Apoptosis, Reward, Morphine, Prefrontal cortex, Conditioned Place Preference, Forced Swim Stress Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S31 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall The Comparison of Dimensions of Activation and Marital Adjustment of Addicted Persons and Persons Under Substance Abuse Treatment (Methadone Treatment ) Narges Fathi Ahmad Saraie1, Narges Fathi Ahmad saraei2, Kianosh Amini3, Maryam Kalhornia Golkar4, Mehdi Kalhornia Golkar5 1. PhD Student Psychology, Isfahan Sciences and Research Branch , Islamic Azad University Isfahan , Iran 2. PhD Student Psychology, Isfahan Sciences and Research Branch , Islamic Azad University Isfahan , Iran 3. PhD.student Ph.D Student Psychology, Isfahan Sciences and Research Branch , Islamic Azad University Isfahan , Iran 4. PhD.student of Psychology, Science and Research branch , Islamic Azad University, Tehran ,Iran 5. Master of Clinical Psychology, Tehran ,Iran Background and Aim Addiction is one of society’s problems that, changed dimensions of activation and marital adjustment .The aim of this study was The Comparison of dimensions of activation and marital adjustment of addicted couples and couples under substance abuse treatment in Karaj. Methods This study is expost facto research. 120 couples were assigned in two groups , ( addicted and couples under substance abuse) and they were asked that complete family addicted and couples under substance abuse scales for gathering data, were the revised scales of. Data was analyzed by SPSS 18 , using by T-test for independent sample . Results Research data showed that there are significantly different between family activation and marital adjustment in addicted and couples under substance abuse. Conclusion The result showed that improvement of marital adjustment and better activation in couples under substance abuse . Keywords Dimensions of Activation, Marital Adjustment, Addiction , Substance Abuse Treatment The Effectiveness of Specific Recall Trinning on Depression in Drug Abuse Patients (Methadone Treatment) Narges Fathi Ahmad Saraie1, Narges Fathi Ahmad Saraei2, Kianosh Amini 3 1. PhD student Psychology, Isfahan Sciences and Research Branch, Islamic Azad University Isfahan, Iran 2. PhD student Psychology, Isfahan Sciences and Research Branch , Islamic Azad University Isfahan, Iran 3. PhD student Psychology, Isfahan Sciences and Research Branch , Islamic Azad University Isfahan, Iran Background and Aim Introduction : This study was aimed to investigate the effectiveness of specific recall trinning on depression in drug abuse patients. Methods Method : In an experimental method, 40 drug abuse patients were assigned in two groups: experimental group(20 males ) and control group (20 males) . During 8 weeks, and 1.5 hours per each week , experimental group participated in specific recall trinning sessions, while control group had not been trained . The instruments for gathering data were Beck depression inventory (BDI). The data were analyzed by variance analysis . Results The results of this study indicated that specific recall trinning decreased depression among drug abuse patients in experimental group(0/005). Conclusion The results of this study indicated that specific recall trinning decreased depression among drug abuse patients in experimental group(0/005). Keywords Drug Abuse Patients , Depression Specific Recall Trinning Psychometric Properties of Coping-Selfefficacy Scale for Substance use Among Adolescent in Isfahan Zohreh Fathian Dastgerdi1, Ahmadali Eslami2 1. Medical University of Isfahan 2. Medical University of Isfahan Background and Aim This study was aimed to investigate the validity, reliability and factor structure of the Coping- Efficacy-Model for substance use among 14-18 year adolescents in Iran, based on European Drug Abuse Prevention(EU-DAP) questionnaire Methods The instrument, using Biton et al. approach, was translated into Persian and then was back translated. Then, a panel of expert examined the questionnaire with regard to cultural sensitivities, clarity of the question, differences and error in their meaning. After item analyses and examine clarity in pilot study, exploratory and confirmatory factor analysis were employed to determine the construct validity of the questionnaire in cross -sectional study used a multi stage sample of 720 adolescent in Isfahan. Results 3 item in assertiveness scale replace with Jessor questionnaire because of lower CVR in cultural adaptation stage and one item in decision making was deleted in item analysis because corrected item-total correlation was lower than 0.3 . other items had acceptable CITC . The alpha reliability coefficient was 80.5 for the total scale and ranged from0.58-0.87 for the subscales. The confirmatory factor analysis related to four-factor model (refusal self efficacy, decision making, assertiveness and communication skill)represented an acceptable fitness(CMIN/df:3.64,TLI:0.91,CFI:0.93,P NFI:0.76,RMSEA:0.06) and accounting for 61% of the variance. Conclusion It is suggested that investigate structural equation model for S32 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall estimating causal relations between coping efficacy construct in Iranian adolescent and use this questionnaire in interventional approach to prevention substance abuse in adolescent. Keywords Substance Abuse, Validity, Reliability, Confirmatory Factor Analysis Zoning Drug Offenses within Women in Ahwaz City; Using Geographic Information System (GIS) Somayeh Fathtabarfirozjaee1, Abdolrahim Asadollahi2, Shahrokh Valizadeh3 1. Dept. of GIS, UAST 2. Assistant Professor, Social Gerontology, Australian Centre on Quality of Life, Deakin University, Melbourne, Australia 3. Dept. of Social Work, UAST Background and Aim The study was aimed to review the social and cultural characteristics of drug women in Ahwaz municipal zones by GIS Methods Statiscal and graphical tests i.e. median center test, standard deviation ellipses, interpolation method (Kernel density test). The community of study is drug women of Ahwaz Women’s Prison in 2014 Results The main centers of drug offending are located in the regions bordering the area of illegal and peripheral settlement i.e. KoutAbdullah, Lashkar-Abad, Xashayar (5 & 6 municipal zones). Illiteracy, population density, and high crime rate areas have significant relationships to each other. Conclusion Spatial analysis of crime or Criminal GIS can be a constructive instrument to security policy in combating the drug. Methods Case study Results This case is expressed about a 28 old man that after consumption of methanol indigestion, symptoms caused blurred vision and rapid progressive lethargic. Acidosis and sever decreased bicarbonate level in ABG was characteristic feature.in neuroradiology evaluation extensive cerebral injuries occurred to basal ganglia. After establishment of disease, in spite of on time diagnosis of MA intoxication and remedial attempts the patient eventually with bilateral optic atrophy and bilateral sever damage and putamen necrosis, rigidity was discharged. Conclusion Considering extensive cerebral damage of methanol-blindness, death ,plegia -high incidence of adulterant alcoholic beverages, prevention of drinking alcohol-methanol-should be thought in media. Keywords Methyl Alcohol,Intoxication,Neurologic Genetic Variation in the OPRM1 Gene is Associated with Drug Abuse Hedyeh Fazel Tolami1, Parvaneh Keshavarz2, Laleh Fazel Tolami3, Mahdiyeh Faraji4 1. Cellular and Molecular Research Center, School of Medicine, Guilan University of Medical Sciences 2. Cellular and Molecular Research Center, School of Medicine, Guilan University of Medical Sciences 3. Cellular and Molecular Research Center, School of Medicine, Guilan University of Medical Sciences 4. Cellular and Molecular Research Center, School of Medicine, Guilan University of Medical Sciences Background and Aim Keywords GIS, Social Pathology, High Crime Rate Areas, Female Drug Offenders Introduction of Specific Neurologic Complication and Manifestation Case due to Methanol Poisoning Amirfarshid Fayyaz1 1. Toxicology Department, Aja University of Medical Science,Tehran, Iran Background and Aim large amount of sodium bicarbonate,hemodialysis,injection of folic acid and sponsorship measures. Methyl alcohol-methanol-wood alcohol-is a kind of alcohols which can be led to MA intoxication due to accidental criminal conception or industrial colorful solvent beverage and adulterant alcoholic beverages to MA intoxication. The start of symptom is variable between 40 mints until 72 hours and 30 to 90 minute after drinking with empty stomach of serum level reaches peak level. Methanol poisoning may produce serious degrees of acidosis, damage to retina, ganglion cells, giving rise to scotoma,vorying degrees of blindness, dilated unreactive pupils and edema.The most important aspect of treatment is the Iv administration of Opioid dependence disorder is a chronic and relapsing disease causing severe impairment, medical complications and economical distress in patients and families. It is estimated that 4% of the world population is using opioids. As all substance abuse disorders, opioid dependence is the result of the interaction of genetic, environmental and drug-induced factors. Methadone, a synthetic opioid, is commonly used as a maintenance therapy for opioid dependence. It works as a µ-opioid receptor (OPRM1) agonist. Genetic association studies have reported that the OPRM1 gene is involved in the physiology of drug and alcohol addiction. The present study aims to delineate the frequency of A118G alleles of OPRM1 among a Iranian population with methadone maintenance treatment (MMT). Methods A total of 200 MMT patients with opium dependence undergoing MMT as outpatients who had referred to Addiction Treatment Clinics in Rasht, were selected. Furthermore 200 controls were selected from normal population without any kind of drug addiction. Several interviewer-administered assessments, including a Treatment Outcomes Profile(TOP) for the amount and frequency of alcohol and Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S33 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall other illicit substance uses in the past 28 days and the Clinical opiod Withdrawal Scale(COWS) for the severity of 11 opioid withdrawal symptoms were conducted before the methadone was administered. Urine specimens were sampled prior to the administration of methadone on the study day. 2mL of Peripheral blood was collected and total genomic DNA was extracted from drug addicts and healthy control using the Qiagen kit. The A118G single nucleotide polymorphism (SNP) in OPRM1 gene was selected in the present study based on previous reports. Genotyping of all samples was done by ARMS-PCR. Two forward primers which 3’ ends were specified to detect the normal allele from polymorphic allele at the polymorphism site were designed for this SNP. All statistical analyses were conducted using SPSS16 software. Results According to allele frequency , The frequency of A allele and G allele were 79.3% and 20.7%, respectively for addicts and about 84% and 16% respectively for healthy volunteers. The frequencies of AA, AG and GG genotypes were 64.6%, 29.2% and 6.% for addict cases and 75%, 17.8%,and 7.14% in healthy volunteers, respectively. There were no significant differences between genotype from cases and controls. Conclusion This study demonstrated that there is not significant association between A118G polymorphism in opioid receptor gene and drug addiction. Considering that, there are other polymorphisms in other sites of this gene. It s better that all µ-opioid gene exones to be investigated. In addition, it seems that in this area, other factors such as epigenetic factors can have an influence on the drug abuse Keywords µ- Opioid Receptor, Polymorphism A118G, Drug Addicts, Methadone New Technologies for Treatment to Substance Abuse Disorder Manijeh Firoozi1 1. University of Tehran Background and Aim Emerging technologies may have several advantages over traditional methods in promoting quality care for addicts. Emerging technologies, such as the Internet and text messaging, have an ever-growing role in providing services to substance abuse treatment. Methods This article summarizes selected examples of emerging technologies that have been developed and implemented as standalone interventions and as part of other face-to-face interventions. It provides a taste of the different opportunities available for implementing emerging technologies as a way to improve the accessibility and effectiveness of services for substance abuse. Results In large part, the types of emerging technologies for use in faceto-face settings mirror. In looking at emerging technologies and the treatment of substance abuse, it is clear that there is a wide range of modalities and settings in which these technologies can be applied. Conclusion It has highlighted interventions that are delivered over the Internet via online social support groups, in primary care settings, in emergency departments, in prenatal care services, and in schools. One final challenge will be to explore how to integrate these new treatment modalities into traditional face-to-face treatment. Keywords Substance Abuse, Treatment, Intervention, Technology, Computer Technology, Internet. Compare the Spiritual Health and Vitality in Patients Undergoing Methadone Maintenance Treatment (MMT) and Inpatient Boarding on Welfare Aliasghar Firoozi1, Farzad Karimnejad 2, Soodabe Basaknejad3, Ali-Asghar Firoozi 4, Mohamad Vatankhah5, Majid Eydi-Baygi6 1. PhD Student in Clinical Psychology, Shahid Beheshti University of Medical Sciences, Tehran, Iran 2. Maser of Clinical Psychology, Member Young and Elite Researchers Club, Islamic Azad University, Thran, Iran 3. Psychologist, Assistant Professor, school of Psychology and Education, Shahid Chamran University of Ahvaz, Ahvaz, Iran 4. PhD student in Clinical Psychology, Shahid Beheshti University of Medical Sciences, Tehran, Iran 5. Master of Clinical Psychology, School of Psychology and Education, Shahid Chamran University of Ahvaz, Ahvaz, Iran 6. Master of Clinical Psychology, Member Young and Elite Researchers Club, Islamic Azad University, Branch Torbate Heydarie, Iran Background and Aim Treatment of addiction is often the form of intervention, the three outpatient, inpatient and residential is done. Given the enormous cost to society of addiction imposes the effectiveness of these treatments is important among the variables that can be demonstrated to be effective treatments is the spiritual health and vitality. The purpose of this study is to compare the spiritual health and vitality in patients undergoing methadone maintenance treatment (MMT) and inpatient boarding on Welfare. Methods This study is a causal comparative. The study population includes all clients residing in boarding facilities and clients in outpatient addiction treatment clinic in Ahvaz. Sampling was a class of multi-stage procedure. By referring these centers Spiritual Health Questionnaire and Vitality questionnaire were distributed to residents at the center. The data were analyzed with the multivariate analysis and with use of software Spss16. Results Results show that scores on vitality and spiritual health and spiritual health indicators, including health, religious, existential and Addicts living in boarding centers being significantly higher in drug addicts is methadone maintenance therapy. Conclusion Due to the fact that the spiritual health and vitality of people S34 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall living in boarding centers being significantly higher People are treated with methadone maintenance therapy is necessary that these centers of education and health promotion that will help accelerate the healing process to be addicts. Keywords Spiritual Health, Vitality, Drug Addicts, Methadone Maintenance Treatment, Inpatient Boarding on Welfare The Study of the Patterns of Traditional and Industrial Drug use Among Women Referred to Addiction Treatment Centers in Tehran. Salman Ghaderi1, Behnam Shahmohamadi.MD2, Seyedeh Mahastamosallaie3, Payman Shiri4, Amir Baghani5 1. Welfer Organization,Tehran,Iran 2. Mehrnam Treatment Substance Abuse Center 3. Welfer Organization, Tehran, iran 4. Welfer Organization, Tehran, iran 5. Shafa Treatment Substance Abuse Center Background and Aim The present study examines the pattern of drug abuse among women referred to the drug treatment centers Methods This is a survey method. The study sample consisted of women referred to the addiction treatment centers in Tehran in 2013, among which, 100 patients were recruited from four centers, available sampling method and were reviewed using discussed focus groups and file studies Results Our findings indicate the decrease in age at onset of drug use amongs women. Given these findings, 32.1% of women have started using drugs under the age of 18. The statistics show a decrease in age of onset drug use amongs women. In terms of marital status, 68% were married, 14% were divorced, and 14 percent were single. Most women referred the centers, had a spouse who is consuming drugs. The results showed that, 38.1% of the study population had started using drugs by propose it from a family member, while the role of other factors, including relatives (20 percent), school friends (7.2%), friends at work (20 percent), and other factors, are subject to other stages. Another important issue was that, 69.1 percent began using drugs from home. More than 80 percent of women in drug abuse had a family member who was using drug Conclusion Our findings suggest the decrease in the age of initiation among women, and the changing role of the family in their attitudes toward drug use, and retention of women in treatment. Therefore, it is essential to design medical interventions as multi-dimensional and focused on the patient, family, and social factors surrounding her, and treatment protocols, attention to the issue of gender and characteristics of women who abuse drugs Keywords Addiction, Retention in Treatment, Drugs and Industrial Investigation of Epidemiology and Trend of Stimulants Use in Tehran Salahedin Ghaderi1, Salahedin Ghaderi2, Roya Noori3, Jamal Khosravi4 1. Hashtgerd Azad University 2. Hashtgerd Azad University 3. Free Researcher 4. Bokan Piam Noor Univercity Background and Aim Among the substances used, stimulants are the greatest potential contributors to the mental, physical, and social traumas. In the recent years, substance abuse patterns have been changing in Iran, so that, nowadays, we are witnessing a considerable growth of stimulant drugs usage, specially methamphetamines and other stimulants in our country. The studies on trends in other countries point to the fact that stimulant abuse is rising throughout the globe. Tehran metropolis, one of the largest cities and capital of Iran, is subject to this phenomenon, and is considered as a good ground for an epidemiological study on new industrial substance. The current study was undertaken to reflect a comprehensive picture of stimulants’ outbreak and trend of usage in Tehran, Iran. Methods This cross-sectional study was carried out using both qualitative and quantitative methods. In qualitative method, in-depth interview techniques and focused group discussion were employed, while quantitative method used procedure analysis technique based on retrospective approach. In qualitative survey, 6000 participants were chosen among over-60-year individuals living in Tehran based on their availability. Results At the moment, 2.3 % of research samples in Tehran are substance users, and 15.1 % are daily stimulant users. Furthermore, 75.1 % of weekly stimulant users live in Tehran, and 9.7 % of them have the stimulant using experience during their life. Anticipated trends had estimated the outbreak growth of stimulant consumption around 6 % by 2012. The growth of crystal meth in the first half of 2001 in Tehran indicated a new trend in using addictive drugs, and this amount, with a highly significant rate, showed an increasing trend. Conclusion The results of the study demonstrated that, among different kinds of existing substances, use of crystal meth was laid in the first place. All usage trends and percentage of consumption initiation over the past years will predict the ascending trend of consumption prevalence in the years to come. It should be noted that the prediction trend of stimulant use is contingent upon preserving the existing situations; however, this prediction’s validity within time series will not be more than three years. Continuing the previous increasing trend, in the absence of intervention, seemed to be rising in the subsequent years. It seemed that the lack of clear-cut and codified rules for crystal meth smuggling, increased domestic production, and subsequently its sharp reduction of 2000 % in price, the information dissemination silence, and lack of awareness-raising in country’s media and educational places can be referred to as the fundamental reasons for the prevalence of this substance in the recent years. Keywords Cocaine, Crystal Meth, Ecstasy, Prevalence, Stimulant Use, Tehran Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S35 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall The Effectiveness of Processing Emotion Regulation Strategies Training in Cognitive Coping of People with Substance Abuse: A Single Subject Study Ali Ghaedniay Jahromi1, Jafar Hasani2, Mohammad Hatami3 1. Alborz University of Medical Sciences and Health Services, Department of Health 2. Department of Psychology, University kharazmi 3. Department of Psychology, University kharazmi Background and Aim The aim of present study was to investigate the effectiveness of processing emotion regulation Strategies training in cognitive coping of People with narcotic and Stimulant substance abuse. Methods In an experimental single case design, 4 addicted people (including 2 people with stimulant substance abuse and 2 people with narcotic substance abuse) who were referred to addiction centers were selected through convenience sampling method and received individual processing emotion regulation strategies training in 10 sessions. These patients matched with 4 addicted people and were evaluated by cognitive emotion regulating questionnaire 6 times (one time in base line, 4 times during the intervention and one time in follow up). In order to analyze data, indicators of process changes, slope change, effect size, Cohen index and review of ups and downs of diagrams were used. Results The results indicated that maladaptive strategies of cognitive coping (i.e. self blaming, catastrophizing, rumination, and others blaming) in subjects with substance abuse were reduced, while adaptive strategies of cognitive coping (i.e. self blaming, catastrophizing, rumination, other blaming) in subjects with substance abuse were increased in comparison with subjects in the control group. Conclusion These results implicate that processing emotion regulation strategies training can improve cognitive coping strategies in people with substance abuse and reduce the rate of getting back to addictive behavior. Keywords Processing Emotion Regulation Strategies, Cognitive Coping, Substance Abuse Blockade of Orexin Type 1 Receptors Inhibits the Development of Morphine Tolerance in Lateral Paragigantocellularis Nucleus: an Electrophysiological Approach Masoumeh Ghaemi Jandabi1, Masoumeh Ghaemi-Jandabi2, Hossein Azizi3, Saeed Semnanian4 1. Department of Physiology, School of Medical Sciences, Tarbiat Modares University, Tehran, Iran. 2. Department of Physiology, School of Medical Sciences, Tarbiat Modares University, Tehran, Iran. 3. Department of Physiology, School of Medical Sciences, Tarbiat Modares University, Tehran, Iran. 4. Department of Physiology, School of Medical Sciences, Tarbiat Modares University, Tehran, Iran. Background and Aim Repetitive administration of opioid agonists is associated with development of tolerance to the effects of these substances and limits their application. Orexin (also known as hypocretin) is involved in morphine tolerance and dependence. The lateral paragigantocellularis nucleus (LPGi) is a key brain region implicated in the tolerance and dependence to opiates. Orexin type 1 receptor (OXR1) has been detected in LPGi nucleus. In this study the effect of OXR1 blockade was investigated on neural activity of LPGi during development of morphine tolerance in rats. Methods Male Wistar rats weighing 250-300 g were used in this study. To incite tolerance, morphine sulfate was injected intraperitonealy (10 mg/kg, i.p.) once a day for 6 days. A selective OXR1 antagonist (SB-334867) was microinjected into the right cerebral ventricle (10 μg/10 μl, i.c.v.) immediately before each morphine injection. On day 7, the effect of morphine (10 mg/kg, i.p.) on neural activity of LPGi was investigated using in vivo extracellular single unit recording. Results In this study morphine injection during 6 days led to the development of morphine tolerance in LPGi neurons which was observed as a significant decrease in responsiveness of LPGi neurons to acute morphine injection. Administration of SB-334867 before each morphine injection could reverse the responses of LPGi neurons to acute morphine injection. Conclusion This study showed that OXR1 blockade by SB-334867 prevents the development of tolerance to morphine in LPGi neurons. Further studies are required to determine molecular and anatomical mediators which are thought to be involved in this phenomenon. Keywords Orexin, SB-334867, Morphine, Tolerance, Extracellular in Vivo Single Unit Recording, LPGi Nucleus Evaluating and Ranking the Effectiveness Factors in the Changing Consumption Patterns of Drugs from the Traditional Drugs to the Industrials Stimulants on the Viewpoint of Drug Users Fateme Ghaeny Niazabadi1 1. Master of Clinical Psychology, Torbatjam Islamic Azad University Background and Aim Identify and classify the factors affecting the consumption patterns of drugs from traditional drugs to the industrial stimulants according to drug users in mashhad during the first quarter of 1392.in this study, the causes of changing in the pattern of using drugs through the addicted people and rating the corresponding scales are being analyzed and evaluated Methods This research is a descriptive research in type of survey and is studied with the use of a statistical population which is comprised of all S36 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall the rehabilitation center and transition centers of mashhad. by using the random sampling four centers selected and 120 people are being studied on the basis of research questionnaires. the method of cronbach’s alpha is used for reliability that coefficient for the questionnaire was 90% and validity questionnaire validity of content type has been approved by judging six specialist and arbiter researchers Results The results of the ranking with 81/3% of the material in the first place, and individual factors, and social factors - cultural, familial factors, and economic factors Respectively, were from second to fifth place.besides, men with 83/3% and divorced women, married men and also rudimentary education have allocated highest demographic Conclusion In the present study, material characteristics, social problems cultural, religious and ideological weakness, economic problems, personal problems, have been effective in changing patterns of drug use Keywords Industrial Stimulants, Traditional Stimulants, Addictive People, Changing Sumption Pattern, Affecting Factors The Socio-Cultural Challenges of Female Drug Users in Tehran Sonia Ghaffari1, Jaleh Shaditalab2, Molouk Azizzadeh3, Parisa Nakhaei4 1. UNODC 2. Tehran university 3. UNODC 4. UNODC Background and Aim In the society where risk factors are socially and culturally rooted, women find it difficult to enter and remain in treatment. Consequently, treatment programs being responsive to female drug users’ needs require acknowledging the realities of women’s lives including the culture of drugs. The objective of this article is to provide information on socio-cultural challenges that affect women’s drug use initiation and treatment. Methods Based on different variables such as type of treatment, 3 treatment institutes were chosen: Khaneh Khorshid, Chitgar Camp and Congress 60. The study has utilized 48 semi- structured interviews as its methodology in the year of 1389/2011. The study includes two groups of respondents; service providers and female drug users. The sampling strategy was purposive. Results Powerless relationships Early marriage is common among most of female drug users. The result is limited knowledge of sexual relations which could increase risk of sexual abuse, unprotected sex and unwanted pregnancies. • Motherhood role and Responsibility of children Lack of childcare is probably the most important factor restricting women’s access to treatment service. - Subculture Women’s status in drug users’ community is inferior too and it can multiple women’s vulnerability and their weak self -esteem. Stigma Women drug users are more stigmatized than men by their family members and society. Therefore, they go unrecognized and awareness of their stigmatized behavior stops them from coming forward. - Social network Stigma leads female drug users to a network of other drug users. This network is very small in size and probably with new types of drugs in the market, is in the diminishing process. - Prostitution When women drug users are poor and dependent on drugs, they are more likely to exchange sex for money, shelter and food. - Violence Violence (at home or in the society) against women drug users’ may take different forms: physical and psychological abuse, unprotected sex, economic violence, Food deprivation, harassment in workplace, … . Conclusion For providing a gender responsive program socio-cultural factors should be considered as well as medical part of treatment. Achieving these goals depends largely on the understanding of gender differences and socio-cultural circumstances which influences drug treatment seeking behaviors. Therefore, these steps are necessary: • Acknowledge that gender makes a difference • Training on cultural norms, values and gender roles, gender based violence, discriminations, and gender differences for service providers is required. Such training would enhance their skills in better understanding of women drug users’ life and increase the chances of women’s remaining in treatment. Keywords Female Drug Users , Social and Cultural Changes Effectiveness of Stress Management Training of Cognitive - Behavioral Therapy on Perceived Stress of Wives Addicted People Faeghe Ghanami1, Samira Soleimani2, Hadi Mansobi3 1. Department of Psychology, Faculty of Educational Sciences & Psychology, Semnan University, Semnan, Iran 2. Department of Psychology, Faculty of Educational Sciences & Psychology, Semnan University, Semnan, Iran 3. Department of Psychology, Faculty of Educational Sciences & Psychology, Torbate jam University, Torbate jam Iran Background and Aim Socio- cultural risk factors that affect women’s initiation of drug use and their treatment process can be categorized into 6 interrelated elements: - Family and relationships • Initiation of drug use In majority of families one or both of the parents were drug users and daughter has initiated drugs within the family. Also, Women more often than men have been introduced to drug with their spouses. • Family’s Support Female drug user usually looses family’s supports when their drug use is disclosed (especially when there are not any drug users in the family). • Early marriages and The substance dependency is one of the major problems in the contemporary world that expansion and the number of victims of drug is added every day. Not only has negative effects on the life of drug addicts, but also the family and relatives of addicts are at risk of multiple injuries of this social phenomena. The present study aims to evaluate the effectiveness of stress management training of cognitive - behavioral therapy on perceived stress husbands were drug dependent persons. Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S37 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Methods This experimental is conducted with pre-test - post-test and follow-up monitoring. The sample included 30 wives of drug-dependent individuals who were randomly assigned to experimental and control groups. Cohen Perceived Stress Questionnaire standardized variables were used in connection with education and intervention, the experimental group performed 10 sessions. Collected data were analyzed using univariate covariance in SPSS software Results The results showed that perceived stress in the experimental group after the intervention of stress management training of cognitive - behavioral therapy significantly reduced compared with the control group. Conclusion According to research results, stress management training of cognitive - behavioral therapy has effective role on reducing the perceived stress of wives addicted people Keywords Stress Management, Cognitive – Behavioral Therapy, Perceived stress, Marital satisfaction, Wives, Drug Dependent Persons Efficacy of Psychological Empowerment Training on Addict men Resiliency in Ivan Farzaneh Ghanbari1 1. MDEducational Psychology.Allameh Tabatabai University Background and Aim Introduction: According to different causes and background s of addiction, its treatment and breaking the vicious cycle needs to a comprehensive health care system. One of interventions is improvement of psychic abilities and increase resiliency that can help to treatment and rehabilitation.Purpose: The purpose of this study was efficacy of psychological empowerment training on addict men resiliency in Ivan. Methods This study was Quasi-experimental with pre-test and post-test and control group. The population was all addict men in Ivan and sample included 30men that with the perform of Conner-Davidson resilience scale (CD_RISC) obtained lowest score. And replacing in the experimental and control groups, randomly. Then the experimental group was trained psychological empowerment during 8session. And the control group did not receive any interventions. After end of sessions performed post-test .The data was analyzed by the analysis of covariance. Results The Results of study demonstrated between addict men resiliency before and after training of psychological empowerment there are significant difference. Conclusion Training of psychological empowerment effected on level of resiliency. Keywords Psychological Empowerment, Resiliency, Addiction Prediction of Tendency to Addiction Based on Social Isolation and Impulsivity in Female High School Students in Ivan. Farzaneh Ghanbari1 1. MDEducational Psychology.Allameh Tabatabai University Background and Aim Introduction: Many researchers knows personality most important predisposing factor for addiction. So broad and deep study and recognition of antecedents can an important factor that preventing of tendency to addiction. Purpose: The purpose of this study was prediction of tendency to addiction based on social isolation and impulsivity in female high school students in Ivan. Methods This study was a correlation. The population included all students of female high schools in Ivan. By using of convenience sampling was selected 150 students as sample. The assessment tools were Woodworth social isolation questioner, Barrat impulsiveness scale (BIS) and Dehkordian preparation of addiction scale. The data was analyzed by Pearson correlation and multiple regressions. Results The Results of Pearson correlation indicated relation between social isolation and impulsivity with tendency to addiction was significant. Results of multiple regression indicated linear combination of social isolation and impulsivity have prediction power of tendency to addiction. Conclusion Tendency to addiction is predicted based on social isolation and impulsivity. Keywords Tendency to Addiction, Social Isolation, Impulsivity The Prevalence of Substance Use in Inpatients of a General Hospital Atefeh Ghanbari Jolfaei1, Neda Norouzi2 1. Assistant Professor of Psychiatry, Minimally Invasive Surgery Research Center, Iran University of Medical Sciences, Tehran, Iran 2. MD, Iran University of Medical Sciences, Tehran, Iran Background and Aim According to the significant effects of substance use on the clinical course and compliance of hospitalized patients in general hospitals, this study aimed at investigating the prevalence of substance use in inpatients of Rasoul- Akram hospital. Methods In this cross-sectional study, through one week all the patients admitted in different wards of Rasoul- Akram hospital, who had inclusion criteria, completed a self- report questionnaire about the S38 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall frequency of cigarette smoking and illicit substances use in past week, past month, past year and entire life. Data were analyzed using SPSS Version 20. Group differences were analyzed using chi-squared, T test and one way ANOVA. Results 423 patients including 218 males (51.5%) and 205 females (48.5%) with the mean age of 48.4+/-18.4 years (11-88 years) were studied. Lifetime prevalence of smoking and illicit substance use was 37% and 29% respectively. Substance use was more prevalent in men and low educated patients. Opioids (16.3%), alcohol (8%), grass (2.3%) and amphetamine (2.3%) were the most abused illicit substances. Conclusion The prevalence of substance use in general hospital is high, therefore it is important to screen the inpatients for all of the substances. Keywords Prevalence, Substance Use, General Hospital The Effectiveness of Training Self-Skills & Problem Solving on Self Confidence in Opioid Dependences hosein Sotudeh1, Ameneh Moazedian2, reza Daneshmand3 1. Iranian National Center for Addiction Studies 2. Education. Research & Treatment Center for Substance Abuse 15 3. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran Background and Aim Regarding absence of Self-Confidence is one of the effective factors on addiction tendency, the life-skills training is necessary to increase ability feeling. In this research, the effect of the training of life skills and problem-solving on the increasing of selfconfidence was examined. Methods The design of this research was semi-experimental design pre and posttest with control group. The population included all addicts under treatment in Tehran Behzisty clinics in spring 2013. 30 addicts were randomly selected and completed the Izenck’s self-confidence questionnaire in pre and post-tests. The experimental group was received life skills and problem-solving training for eight sessions. No training given to control group. Results The analysis of covariance showed that after training, the selfconfidence was significantly different between experimental and control groups. The experimental group significantly had higher self-confidence than the control group Conclusion The results of this study indicated that the training of life skills and problem-solving can increase the addicts’ self-confidence. Keywords Self-confidence, life skills training, problem-solving training, addiction The Effectiveness of the Life Skills and Problem-Solving Training on the Increasing of Addicts’ Stress Coping under Treatment with Buprenorphine Hossein Gharaati Sotudeh1, A. Moazedian2, Reza Daneshmand3, M. Noori4 1. Iranian National Center for Addiction Studies 2. Education Research &Treatment Center for Subtance Abuse 15 3. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 4. Education Research &Treatment Center for Subtance Abuse 15 Background and Aim The purpose of this study was to investigate the effect of life skills and problem-solving on increasing of stress coping among addicts. Methods The design of the study is semi-experimental with pretest -posttest and control group. The population of the study was all addicts to opioids Behzisty’s self-referred centers in Tehran. 30 addicts were randomly allocated into experimental group (N=15) and control group (N=15). The life skills and problem-solving training was demonstrated in 8 weekly sessions on the experimental group while the control group received only the Agunist. Stress coping method (CS-R) questionnaire were completed by both groups before and after intervention. The data was analyzed using covariance analysis. Results There was significant difference in stress coping between two groups after intervention. Results demonstrated that the life skills and problem-solving training led to significant increase in experimental group stress coping. Conclusion Regarding to effectiveness of the life skills and problem-solving on stress coping, it may also be used as a supplement method decreasing stress among addicts. Keywords life skills, problem-solving training, stress coping, Addicts Attitudes of Iranian Population Aged 16 to 45 Years towards the Use of Crystal (Meth) in 2013 Mariet Ghazarian1, Azadeh Olyaei, MS3, Zahra Esfahani, MS4, Hassan Rafiee, MD, MPH5, Hooman Narenjiha, MD6, Hamid Reza Khoddami Vishteh, MD.7, Mohsen Roshanpanjouh, MD8 1. State Welfare Organization, Prevention Deputy, Drug Prevention Office, Tehran, Iran 2. State Welfare Organization, Prevention Deputy, Drug Prevention Office, Tehran, Iran 3. State Welfare Organization, Prevention Deputy, Drug Prevention Office, Tehran, Iran 4. University of Social Welfare and Rehabilitation Sciences 5. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 6. Research Center of University of Social Welfare and Rehabilitation Sciences 7. State Welfare Organization, Prevention Deputy, Drug Prevention Office, Tehran, Iran Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S39 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Background and Aim The use of Meht crystal has many effects, particularly in teens and young people, and their attitude towards drug use might play an important role in the use of this substances. Since the planning and successful implementation of drug prevention programs is almost impossible without assessing the attitude of the community, the aim of this study was to investigate the attitudes of Iranian population toward the use of crystal. Methods This cross-sectional study was conducted on 1000 citizens, aged from 16 to 45 years, in Tehran, in 2013. The participants were selected using random sampling in 75 places. The measuring instrument was a researcher-made Questionnaire on Assessing “attitude toward the Use of Crystal (Meth) in Iranian Adolescents and Young adults” with 25 questions. The interviewers were explained the aim of the study to the participants in public places such as streets, parks, etc, and after taking informed consent, they asked the demographic information as well as questions on crystal. The participants were divided into high and low risk groups based on their scores in the questionnaire. Results The mean age of the participants was 26±6 years. 551 participants (55%) were male, 371 (37%) were married and 753 (75%) had high school degree or higher education. Of all the studied population, 918 people (92%) did not have an experience of crystal use; however 265 people (29%) had seen crystal. Moreover, 42 persons (4%) had previously used crystal for less than five times in their lifetime; 40 (4%) were crystal users with mean age of 28±5 years and 3 of them (8%) were female. Of those using crystal, 33% were married and 53% had a high school degree or higher education. From those who did not have any experience of crystal use or had used for less than five times, 919 people (96%) reported crystal as a hazardous material, 59 (6%) considered themselves at risk of crystal use, and 39 (4%) had attributed positive effects to crystal. Overall, based on the total score of the questionnaire, 30% of participants were identified as high-risk. There was no significant difference between high and low risk groups in terms of age and education level (p>.05), however most of the people in risky group were male (p<.001), and single (p=.032). Conclusion The findings of this study showed that 4% of the sample population was crystal users and 4% used crystal for less than five times in their lifetime. One-third of the all participants were found to have high risk attitude that most of them were single and male. According the risks of crystal use especially at adolescents and young people, it is recommended to plan implement drug prevention programs to raise the awareness and change the attitudes toward crystal use in risky ages. Keywords Attitude, Crystal, Substance use, Adolescents, Young adults The Effects of a Media Campaign on Attitude of Adolescents’ and Young adults’ towards the Crystal (Meth) Use in Tehran in 2013 Mariet Ghazarian, MS1, Zahra Esfahani, MS2, Azadeh Olyaei, MS3, Hooman Narenjiha, MD, MPH4, Hassan Rafiee, MD, MPH5, Hamid Reza Khoddami Vishteh, MD6, Mohsen Roshanpanjouh, MD7 1. State Welfare Organization, Prevention Deputy, Drug Prevention Office, Tehran, Iran 2. State Welfare Organization, Prevention Deputy, Drug Prevention Office, Tehran, Iran 3. State Welfare Organization, Prevention Deputy, Drug Prevention Office, Tehran, Iran 4. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 5. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 6. Research Center, University of Social Welfare and Rehabilitation Sciences 7. State Welfare Organization, Prevention Deputy, Drug Prevention Office, Tehran, Iran Background and Aim In recent decades media campaigns have been implanted to change health behaviors. In media campaigns, media messages are displayed to a large population using different tools within a specified period of time, for specific groups of audience and they could influence the attitude of population. According to some researches in our country, the trend of drug use has been changed from opiates to stimulants such as crystal; however, most studies have focused on the drug use patterns rather than the attitudes toward drugs. The aim of this study was to assess the effects of media campaign on changes in attitudes toward the use of crystal in Tehran. Methods This study was conducted in 2013. First, a total of 1,000 people aged 16 to 45 years were selected from the city of Tehran. Their attitude toward the crystal use was measured via a researcher-made attitude questionnaire. Based on the findings, a media campaign was designed and implemented in the city. After the campaign, a new sample of 1,000 participants was selected in the city and the attitude was measured again. The total score of attitude and its subscales were compared before and after the intervention. In addition, based on the scores, participants were divided into risky and low risk groups. To analyze the data, chi-square test, t-test and two-way ANOVA were used. Results The mean age of the participants was 27±7 years, 1030 participants (52%) were male; 820 (41%) were married and 1556 people (78%) had high school degree or higher education. Of all the studied population, 1861 people (93%) did not have an experience of crystal use. Moreover, 70 persons (4%) of the total population had previously used crystal for less than five times in their lifetime; 69 people (4%) were crystal users. Total score of attitude toward the crystal use after the intervention had a significant increase compared with that before the intervention (p<.001). Attitude scores for subscale of physical and mental symptoms, sexual, recreational and occasional use, psychotic symptoms, and the prevalence of crystal use had become significantly increased (p<.05), whereas the score of attitude toward socializing and friendship with crystal users was not significantly different before and after intervention (p≥.05). In addition, There was seen a significant decrease in the S40 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall number of people in risky group after the intervention (p<.001). Analysis of variance was conducted in order to assess the effects of the demographic variables (age, sex, marital status, education) on the attitude scores; and the results showed an improvement of attitude toward crystal use after the intervention. Conclusion The media campaign had a significant effect in changing adolescents’ and young adults’ attitudes toward the crystal use, and such effects remained stable even after eliminating the effects of age, sex, marital status, and education. According to the risks of crystal use, especially among adolescents and young adults, media campaigns can be used as one of the effective methods of changing attitudes. Keywords Adolescents, Attitude, Crystal, Media campaign, Substance use, Youth Comparing Parenting Style Schemas in Two Groups of Opiates Users and Normal Individuals Mahnaz Ghiasi1, Shirin Ezadi2, Sedigheh Safaei3, Farah Mamlekat Doost4 1. PhD. Student of Psychology, Department of Psychology, University of Alzahra, Tehran, Iran 2. M.A. of Psychology, Islamic Azad University- Science and Research Branch, Tehran, Iran 3. MA. of Educational Sciences, Department of Psychology, University of Semnan, Semnan, Iran 4. MA in Exceptional Children Psychology, Islamic Azad University- Center Tehran Branch, Tehran, Iran Conclusion When parenting schema is formed in an individual as maladaptive, it leads to a special attitude that causes an individual to look at the world through it. Over time, this issue will result in an individual’s better understanding, emotions and unique thrills, as a result the comparative performance will continue. One of the external features of comparative performance is to seek refuge in opiates. Because when the parenting schemas are activated in intrapersonal interactions, it will stimulate thrills and negative schemas, as a result the individual (opiates user) tries to cut down by abusing drugs. Hence, the parenting schema can make a great contribution to opiates usage. Keywords Substance Abuse, Opiate Addiction, Parenting Comparison of Early Maladaptive Schema Between Candidate Adult for Addiction Withdrawal in Comparison with Non-Addict Adults Nafiseh Rafiee1, Maryam Ghorbani2 1. Teacher Assistant in Educational Science, Payam-e Noor University. Tehran. Iran 2. Assistant Professor in Psychology, Payam-e Noor university. Tehran. Iran Background and Aim Background and Aim Family is a kind of structure that because of extensive actions it influences individual behaviors in a significant way. Parenting style is one of the factors that plays an important role and will influence individual cognitive process while encountering stressful and unpleasant situations. According to schema therapy of Young (1991) if parenting style is not efficacy, schemas based on this approach will be maladaptive and will lead to dangerous behaviors such as opiates abuse. Substance abuse is a major issue of concern today is the field of health. Understanding the emotional, behavioral and cognitive characteristics of this disorder, can lead to better prevention and treatment. One of these aspects is cognitive schemas. Schemes, including templates or themes are deep and widespread that is composed of memories, emotions, cognitions and physical sense. The purpose of this study is to identify the early maladaptive schemas in patients with substance abuse and normal individuals. Methods Methods This research was conducted in the summer of 2013. The sample included 200 opiates users between 16 to 60 years of age (M=34, SD=9.08) and using accessible sampling. The normal group consisted of 218 individuals within the age of 16 to 60 (M=35, SD=7.96) and were sampled by random sampling method. All participants answered Young Parenting Inventory (YPI). The questionnaire included 72 items and 17 subscales in which the respondents ranked their parents based on their behavior towards them. Shefield, Waller, Emanuelli, Murray and Meyer (2005) reported Cronbach’s alpha 0.70–0.92. Yazdandoost and others (2008) reported reliability coefficient of 0.69 for the mother form and reliability coefficient of 0.80 for the father form. Data was analyzed by the statistical method of T-Test using statistical software SPSS-20. Results users and the normal group in the parenting schema relevant to mothers had a significant difference and resulted in t=9.89. The result of parenting schema relevant to the fathers was t=12.65 and had a significant difference (P<0.05). The descriptive results showed that the period of using opiates among users was with the mean of 4.41 and standard deviation of 6.77. The analysis of the data showed that the group of opiates This was a causal–comparative study. The sample was selected using convenience sampling and consisted of 50 addicts and 70 non-addicts in Tehran. All participant completed the Young Schema Questionnaire (YSQ). Data were analyzed using the independent T test Results Result showed that there were significant differences between two group in emotional deprivation (t=3/51), abandonment (t=3/5), dependence/incompetence (t=4/25), defectiveness/shame (t=3/49), entitlement (t=3/39) and enmeshment (t=2/5). Conclusion It seems that early maladaptive schema play an important role in understanding the fundamental differences between addicts and non-addicts. Due to the formation of these schemes in childhood, parenting can provide suitable conditions for the modification of maladaptive schemas and helped to prevent this disorder. Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S41 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Keywords Schema, Early Maladaptive Schema, Addiction Disorder Effect of Drama Therapy on Impulsivity and Substance Use Craving in Addicted People Behrooz Golchai1, Bahman Akbari2, Reza Vatan khah3, Masoumeh Allahi4, Ramin Kasb Gar5 1. Guilan Medical University Medical Student 2. Islamic Azad University Science and Research Branch PhD of Psychology 3. Islamic Azad University Science and Research Branch PhD of Psychology 4. M.A in Psychology Clinic 5. Islamic Azad University Science and Research Branch M.A Psychology Background and Aim Addiction is among the unwelcome social problems since it damages their brain and behaviors. Researchers have applied effective prevention or treatment methods to reduce the negative impacts of substance use craving on people and family. A technique applied to treat mental and emotional problems is drama therapy. In this work, “effect of drama therapy on impulsivity and substance use craving in addicted people” was investigated. Methods This work was carried out based on a trial work method with a pre-test and post-test design using a control group selected from a rehabilitation center in Rasht. Among 330 trials units who achieved highest score, 30 ones were selected through the convenient sampling method and were controlled into two test and control groups. The trials were subject to ten 90 minute sessions of drama therapy training on a weekly basis. To gather required data, the Bart impulsivity questionnaire and substance use craving thoughts questionnaire (CBQ) were used. Results The findings of present work show that drama therapy trainings has an effect on reduced impulsivity (p < 0.001, F(1,26) = 17.78) and reduced substance use craving (p < 0.001, F(1,26) = 18.70) of addicted people. Conclusion The results of this work showed that drama therapy training can considerably reduce impulsivity and substance abuse of the addicted people by improving their skills such as consciousness, decision making power, responsibility, and having the ability of saying “no”. Keywords Drama Therapy, Impulsivity, Substance Abuse, Addicted Investigate the Effectiveness of Lfe Skills Training Applying Storytelling on the Shyness of Student of Addicted Parents Nasrin Goodarzy1, Morvarid Safari Vesal2 1. Semnan University 2. Semnan University Background and Aim The purpose of the present study was to investigate the effectiveness of life skills training applying storytelling on the shyness of children, aged 11 years old. We used an experimental pretest, posttest with control group paradigm. The population of the study was included all shy children in Tehran city .The sample consisted 39 children (experimental =20, control =19) who were randomly selected and the subjects received 14 sesstion of life skills training. A measure of shyness was collected using Stanford Shyness Scale and analysed by the analysis of covariance(ANOVA).The research result revelead significant difference between 2 groups .The life skille training decrease the shyness (p<0/05).Although the drug abuse by parents has been positive linked to children’s shyness ,but We concluded that life skills training by storytelling could be considered as both a way of primary prevention and , useful effective treatment for children shyness . Keywords Storytelling, life skills, shyness, addicted parents Methods Sample consisted 39 children (experimental =20, control =19) who were randomly selected and the subjects received 14 sesstion of life skills training. A measure of shyness was collected using Stanford Shyness Scale and analysed by the analysis of covariance(ANOVA) Results The research result revelead significant difference between 2 groups .The life skille training decrease the shyness (p<0/05) Conclusion Although the drug abuse by parents has been positive linked to children’s shyness ,but We concluded that life skills training by storytelling could be considered as both a way of primary prevention and , useful effective treatment for children shyness . Keywords Storytelling, Life skills, Shyness, Addicted Parents Exercise Addiction, Risk-Taking Behaviors and Mental Health Abolfazl Goodarzy1, Hamid Kazemi2, Salman Ghorbani3 1. Department of Physical Education, Payam-e Noor University, Tehran, I.R. Iran 2. Assistant Professor of Department of Psychology, Payam-e Noor University, Tehran, I.R. Iran 3. M.A Student in Clinical Psychology, Islamic Azad Un. Najaf Abad Branch. Background and Aim One of the new addictions that less dealt with is exercise addiction. Occurrence of this addiction has cognitive emotional and social dysfunctions and these consequences have not been studied yet. Therefore, the present study examined the relationship between exercise Addiction and risky behavior with mental health in physical education students as an example that are at risk form this form of addiction. Methods In a correlational study, 150 male and female students in physiS42 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall cal education courses selected and were evaluated with exercise Addiction Inventory, Risk-Taking behavior Scale and symptoms the checklist-90-rewised. Data obtained were analyzed via –SPSS 18 and regression analysis. Results Regression analysis shows that total score of exercise addiction showed a significant relationship with Risk-Taking behaviors subscales and meaningful contribution in predicting mental health (R=0.58, R2=0.33, P<0.05). Tendency for violence significantly contribute to predicting somatization (21%), OCD (20%), interpersonal sensitivity (17%), Depression (16%) and aggression (39%). Total score of exercise addiction was a significant predictor of anxiety (28%) and total score of exercise addiction and tendency for alcohol are predictor for psychosis (27%). Conclusion Explanation of the findings can be made that although exercise is one of the important components of life style, and have a positive impact on the mental health, but engaging in excessive exercise or exercise addiction can be an important factor for improving RiskTaking behaviors and symptoms of mental disorders in individual. Keywords Exercise addiction. Risk-Taking Behaviors. Mental Health. The Efficacy of Matrix Model in Emotion Regulation and Prevention of Lapse in Methamphetamine Abusers Results Results The results of Mann-Whitney U in comparison between two groups (In view of the differences between pre and posttest) shown that there was notany significant difference in emotional regulation difficulties (p=0/75). But decreased in lapse rate between two groups was significant (p= 0/001). Conclusion Conclusion in general, results of this study shown that Matrix model is not effective in emotion regulation, but reduced lapse rate in patient. Keywords Matrix Model, Emotional Regulation, Lapse, Methamphetamine Abuser The Effectiveness of Cognitive Behavioral Group Therapy on Quality of Life of Women Treated With Methadone Nahid Hadavi1, Mohammad Shahkarami2, Mina Papi3, Nooshin Malayeri4 1. M.A Student in Oloum Tahghighat University of Boroujerd 2. M.A Student in Family Terapy Kharazmi University of Tehran 3. Ms in Counseling 4. M.A in Family Terapy Background and Aim Rohulla Hadadi1, Mina Noori2, Reza Rostami3 1.University of Tehran 2. Rehabilitation and Welfare Sciences University 3. University of Tehran Background and Aim Introduction: The Use of Amphetamines have Stanch and Unpleasant effects on various aspects of abuser`s life that can be challenges for therapists in this field. One of the prominent effects of a defect in emotional processing, self-regulation and a decision making that endures despite abstinence from drug use. Thus, the formulation of a more comprehensive treatment plan that is consonant with the needs of patients have always been considered. One of the most effective therapies in recent years has been the Matrix model. although, many studies suggest that Matrix model is effective in prevention of relapse but efficacy of this model in improvement of other problems such as emotional problems is the question, so this research was conducted to assess the efficacy of Matrix model in improving emotion regulation and decrease of lapse rates in methamphetamine abusers. Methods dex “ASI” and measures of emotional regulation difficulties scales “DERS”. Patients lapse through testing, morphine and methamphetamines were evaluated onc a week. for data analysis was used of Descriptive statistical methods and Mann-Whitney U. Materials and Method: In this semi-experimental study, 30 men methamphetamine abusers who referred to substance abuse treatment center in Tehran for receiving medical services, was selected and randomly assigned to two, experimental and control,groups. Experimental group were treated by Matrix therapy in 24 sessions (90 minutes) twice a week and the control group did not receive serious intervention. All participants in the study completed in pre intervention and immediately after that, the Addiction Severity In- Today is undoubtedly one of the factors that led to the foundation of life on the breaks and provide family dispute, an addiction is. Trauma when the status quo is greater than the wives of smokers are aware of their partners. In such circumstances, spouses of addicts, life expectancy and quality of life is impaired social relationships and brief sadness, grief, loneliness, shame and insecurity, psychological domination is the rule of life. Methods This quasi-experimental investigation of the pre-test and posttest control group of women drug addicts center Svmsrf 18 persons were selected and divided into two groups and they were divided into control and experimental groups received 10 sessions of cognitive behavior therapy, the control group received no treatment. Data collection was carried WHO Quality of Life questionnaire of 26 questions, data analysis and the level of covariance was performed with spss Results The results showed no significant difference between the two groups after controlling for pre-test results (p <0/005) groups, quality of life after CBT showed greater. Conclusion The results demonstrate the effectiveness of cognitive behavioral therapy CBT has been shown to increase the quality of life for women who are addicted to research Domari et al (2000) and Newt and Huron (1992) is consistent with . Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S43 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Keywords Cognitive-Behavioral Group Therapy, Improving the Quality of Life of Patients Treated Women Gene Expression and Psychiatric Analysis of 50 Iranian Methamphetamine Addicted Individuals Arvin Haghighatfard1, Mozhdeh Amini Faskhodi2 1. Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran 2. Department of Biology, Tehran Medical Branch, Islamic Azad University, Tehran, Iran Background and Aim Methamphetamine is a neurotoxin and potent psycho-stimulant of the phenethylamine and amphetamine classes that is used to treat attention deficit hyperactivity disorder (ADHD) and obesity. Schizophrenia is a chronic multifactorial and multigenic , disabling psychiatric disorder that affects about 1% of the population worldwide. Symptoms of schizophrenia including positive, negative and cognitive deficits. majority of methamphetamine addicted have the same psychiatric symptoms like hallucination and bizarre behavior. Researches suggesting that some parts of brain in schizophrenic patients and methamphetamine addicts are neurodegenrated but the mechanisms of this degeneration is not clear. gene expression analysis could help to understand the molecular mechanisms of this neurodegeneration and explain the cause of same psychiatric symptoms in these two groups .this researches also can help to understand the pathogenesis of schizophrenia and methamphetamine effect on brain. Methods Blood samples collected from 50 addicted ,50 schizophrenic not addicted patients and 50 normal controls in the same range of age(23-30years old). RNA of whole blood extracted by column method kit . cDNA synthesized and expression of 3000 gene investigated with DNA microarray technique. Microarray results for two gene NDUFS1 and NDUFS2 confirmed by Real Time PCR syber green method . PANSS ,positive and negative syndrome scale and Brief Psychiatric Rating Scale (BPRS)tests operated from all samples by psychiatrist team and results analyzed by SPSS and Bonferroni statistical software. Results Expression of 12 gene had been affected in patients and addicts. over expression of NDUFS1 and NDUFS2 , and decreasing of expression in 5HT2a,DRD2,DRD3,BDNF,DISC,NRG1,MAOA, bcl2,NDUFV1 and NDUFV2 . Over expressions were significant in schizophrenics & addicts in compare with normal but Over expressions were significant in addicts in compare with schizophrenic patients.In PANSS and BPRS psychiatric test the negative symptoms were in same scores for addicted and schizophrenic groups. but positive symptoms including hallucination and exaggerated behaviors showed significantly higher scores in addicts. Conclusion In our samples a significant affects of Metamphetamin and schizophrenia on expression of several genes especially in mitochondria complex 1 subunits genes have been detected.It seems that the mechanism of neurodegeneration in both group is the same but rate of degeneration is higher in methamphetamine addicts. Also our results suggesting that there is a directed relation between NDUFS1 and NDUFS2 over expression and higher score of positive symptomes in methamphetamine addicted individuals. same research in future can increase our knowledge about pathways that methamphetamine affecting on them in human. Keywords Methamphetamine-Gene Expression - Schizophrenia - PANSS - IRANIAN Effect of 12 Months Exercise and Physical Activity on the Prevention of Relapse in Recovered Heroin Male Addicted Masoud Haji Rasouli1 1. Islamic Azad University ,Branch of Islamshahr Background and Aim Opiate Addiction is one of the worst problem ,in approximately all countries . United Nation Office of Drug and Crime (U.N.O.D.C) has reported , that there is more than 250 millions peoples in the world ,who they are drug Abusers {U.N.O .D.C-2009} . Genetical ,Psychological and social Abnormalities are the main reasons for prevalence of Drug Addiction, HIV/AIDS and other problems.at the other hand ,Sports and Physical Activity can affect the Health ,mood and Social statues among All the peoples. And can be useful as a preventative factor against Addiction.The aim of this study w a s to explore the effect of 12 months exercise and physical activity on the prevention of Addiction relapse in Heroin Addicted men, who had managed to quit using Heroin and they were free of drug. Methods The Research method is Semi-experimental .Samples were 30 Heroin Addicted who had been treated and all of them do not use any Addictive substance .The average of age ,duration of addiction and other effective demographic factors were calculated .samples were divided into two groups of 15 .15 persons as experimental group ,who were given exercise as Aerobic ,non- contact and widely types of play and games. the training program was 30 -60 minutes submaximal activity ,daily and3 times weekly, Intensity of training were regulated according to each samples Physical and Mental condition. the other 15 were merely subject to health monitoring as the Control group .Statistical method including independent Matched Pair T test ,Mann whitney post hoc and Pearson correlation test were used . At the end of project period, all subjects ,were given Urine Test and the Urine samples were evaluated by using T.L.C Lab method. Results The result showed that after 12 months ,12 subjects of control group had relapsed back into drug Addiction ,but in the experimental group ,there was just 3 persons , who were relapsed again, there was no any significant difference in age or duration of drug abuse between samples in two groups ,so the results of this study may be attributed to the effect of physical Activity during the 12 months ,duration of projects .statistical evaluation showed that the difference was significant (P<0/05). S44 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Conclusion From the finding of this study, it can be inferred that divers and uncompetitive aerobic exercise , can be effective in the prevention of relapse in recovered Heroin addicted and reasonable appropriate exercise with the increased level of Physical and Mental health of the subjects can be used as a low-cost, non - invasive and effective method in the treatment and prevention of relapse to drug abuse. Keywords Opiate Addiction, Heroin, Relapse, Exercise, Treatment The Effect of Family Education on the Temptation Status of Addicted People under Treatment Hasan Hajipour , Elahe Azizi , Maryam Rezaee 1. Welfare Organization 2. Welfare Organization 3. Welfare Organization 1 2 3 Background and Aim The Effect of Family Education on the Temptation Status of Addicted People under Treatment H. Hajipour, E. Azizi, M. Rezaei Boroon Abstract: Considering the importance of family-based treatment approaches in the treatment and prevention of relapse in addicted clients, this study aims to determine the effectiveness of family education on temptation status of addicts, which were in Methadon Maintenance Therapy (MMT) plan. This research was conducted in the year of 1390, in the city of Mashhad. 250 of addicted people were being treated which were selected from the Khorasan Razavi province clinics. A simple random sample of 126 patients in the test group and a control group of 124 patients were used. Initial interviews with the subjects in the experimental group and the control group were done. One of the close family members who was mainly the dependent spouse, selected to be used in this study. The test group were pre-examined, and then the close family member which was introduced, trained under specialist to resist temptation by the designed model. This family cooperation model was planned by psychologists and psychiatrists that work in MMT clinics. The training schedule lasted 4 sessions, and the test group was post examined finally. The collected data were analyzed by non-parametric Whitney U-test. The comparison results showed that, the reference temptation status scale, and his resistance to temptation found significant differences between the experimental group and the control group. In conclusion, the statistical analysis showed that, the family education is effective in reducing the temptations of addicts to leave the drug (s). Key Words: Family education, Addiction, Temptation. Methods Simple random sample Results Effectiveness family education on reduced crayving substance abuser Conclusion Family education is effect in reduced cryving in substance abuser in outpationt center Keywords Family Education - Crayving-Substance Abuser The Impact of Mindfulness-Based Cognitive Therapy for Addicted Women Prisoners Depression Mahin Hamidi1, Hojjat Seyed Kaveh2, Sorour Kazemi3, Arash Akaberi4 1. M.A. of Clinical Psychology, North Khorasan University of Medical Sciences, Addiction and Behavioral Sciences Research Center. Bojnurd, Iran 2. Assistant Professor of Psychiatry, North Khorasan University of medical Sciences. Addiction and Behavioral Sciences Research Center. Bojnurd.Iran 3. B.A. of Clinical Psychology, Addiction and Behavioral Science Research Center. Bojnurd 4. M.Sc of Biostatistics, Addiction and Behavioral Sciences Research Center, Bojnurd, Iran Background and Aim Women prisoners have been identified as suffering higher levels of emotional distress then their male peer. An estimated 73% of females in state prisons, compared to 55% of male inmates, had a mental health problem.Major depressive disorder (MDD) is the most common severe mental illness in prison settings. At present reported much rates of depression and anxiety in substance abusers so that about 40 percent of people who commit suicide have had a history of drug abuse. The high rates of depression among substance-abusing are female prisoners. Mindfulness-based cognitive therapy (MBCT) is a new group-based intervention for prevention of depression. Mindfulness is “being attentive to and aware of what is taking place in the present”. The purpose of this study was to investigate the effect of mindfulness-based cognitive therapy on symptoms of depression in addict women jailed. ( the aim of mindfulness training is not to induce relaxation, but instead to teach nonjudgmental observation of current conditions, which might include autonomic arousal, racing thoughts, muscle tension.) Methods A total of sixty patients participated with major depressive disorder and history of drug abuse, aged 18 to 60 years, 28 patients were in the experimental group, and 32 patients were in the control group. Groups were matched in terms of marital status, educational status and Drug use. Semi-experimental method to test - retest reliability were used for both test and control groups. The treatment used in this study was the Mindfulness-Based Cognitive Therapy protocol detailed in Segal, et al (2002a).The program ran for eight consecutive weeks, and involved weekly evening sessions of 2.5 hours duration Results MBCT was associated with statistically significant reductions in depression from pre to post treatment. Depression scores in experimental group decrease -19.1+11.9 then the control group showed a decrease in depression score was -2.5 +14.3.overall Patients who recovered MBCT showed greater cognitive reactivity and the mood was better than no intervention group. Conclusion Results of this meta-analysis indicate that MBCT is an effective intervention for patients with MDD in remission. MBCT effects are mediated by enhancement of mindfulness and self- Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S45 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall compassion across treatment. One facet of mindfulness, observing one’s internal state, was associated with more moderate affective forecasts as well as a decreased susceptibility to the impact bias.Consequently we believe the results of this study will have significant applications for depression care .It is suggested that ongoing MBCT skills and practice may be important for relapse prevention over the longer term. Larger randomized studies of the mechanisms of MBCT with longer follow-up periods are recommended. Keywords Mindfulness-based cognitive Therapy (MBCT), Depression, Drug of abuse, Prisoners Women The Comparison of Personality Characteristics of addicted Men and Women in North Khorasan Mahin Hamidi1, Souror Kazemi2, Seyyed Kaveh Hojjat3, Arash Akaberi4, Ali Rahemi Nasab 5, Golnaz Vahidi Borji6 1. M.A. of Clinical Psychology, Addiction and Behavioral Science Research Center, Bojnurd 2. B.A. of Clinical Psychology, Addiction and Behavioral Science Research Center, Bojnurd 3. Assistant Professor of Psychiatry in North Khorasan University of Medical Science.Addiction and Behavioral Science Research Center, Bojnurd 4. B.A. of Clinical Psychology, Addiction and Behavioral Sciences Research Center, Bojnurd, Iran 5. Mastudentclnical Psychology . Khorasanshprrisons.Iran.Bojnord 6. B.A. of Clinical Psychology, Addiction and Behavioral Science Research Center, Bojnurd Background and Aim Crime has a long history as the human history and the issues related to criminal and prisoners, specially their relationship with personality issues, is one of the most challenging and most active research fields. Many of addicted people have personality disorders .The main objective of this research is to compare 5 personality factors: neurotic ism , extroversion, openness, agreeableness, and conscientiousness of addicted male and female prisoners. Methods This research is an analytical-sectional research that has been conducted in 1393. In this study, after gaining their consent, 53 addicted female prisoners and 69 addicted male prisoners were investigated. All of them completed the 5-neo-factor character questionnaire. The comparison of the 2 groups was conducted in terms of qualitative variables using K square test and the comparison of quantitative variables was conducted by independent T test. 5 personality factors were compared in the 2 groups using multivariate test. The analyses of this study were performed by SPSS 22 software and the level of significance was assumed in 0.05. Results The investigated men and women had no significant difference in terms of age and marital status. The multivariate analysis showed that the addicted men and women had a significant difference in terms of personality characteristics(Wills’ Lambda=0.880, P-VALUE=0.010). The results of comparing 5 big factors of personality in the addicted men and women showed that men have a significant higher score than women in extraversion as well as openness (p = 0.015 and p = 0.033, respectively). The average of neurosis, conscientiousness and agreeableness items showed no significant difference between men and women Conclusion The results of the present research showed that the score of extraversion and openness in addicted men is higher than addicted women. The level of extraversion in the addicted women is low and they have a higher level of maladaptive and neuroticism.Therefore, not also they have a problem in compatibility with others, but also because of their low level of extraversion they have no interest toward social contribution, and on the other hand, they isolate themselves from the society because they are addicted and so their incompatibility is intensified. Addicted people who are extroverted have a tendency toward social groups in order to communicate with people who have a similar problem. Therefore it can be concluded that special personality characteristics prepare people for drug abuse and consequently it would entail various social damage and finally crimes. Keywords Personality Traits, Addicted Men, Addicted Women An Evaluation of Substance Abuse Among Prostitutes Mahin Hamidi1, Golnaz Vahidi Borji2, Seyyed Kaveh Hojjat3, Arash Akaberi4 1. M.A. of Clinical Psychology, Addiction and Behavioral Science Research Center, Bojnurd 2. B.A. of Clinical Psychology, Addiction and Behavioral Sciences Research Center, Bojnurd, Iran 3. Assistant Professor of Psychiatry in North Khorasan University of Medical Sciences. Addiction and Behavioral Sciences Research Center, Bojnurd, Iran 4. B.A. of Clinical Psychology, Addiction and Behavioral Sciences Research Center, Bojnurd, Iran Background and Aim Social consequences of prostitution are not clear in law and society. Prostitution is a sexual violence which entails financial benefit. The evidence indicate that the majority of female patients hospitalized for substance abuse are either infants or in later periods of life. Substance abusers with records of prostitution are at high risks of psychological disorders such as anxiety, depression and bad health. Thus, this study aims to evaluate prostitutes identified as substance abusers. Methods This descriptive study is a covariance research and its population consists of all prostitutes of northern Khorasan (94 subjects) who were selected randomly and who then answered a research-made inventory. Collected data were analyzed by K squared analysis and SPSS version 22. Results 57% of population was identified as addicts. Addiction was declared by 5.39% as the cause for prostitution and 1.8% declared poverty. In the non-addict group no such difference was found. In this group, the maximum proportion was related to the proclivity to sex (28.2%), poverty (23.1%), and pressure (15.4%). Two groups didn’t differ over the cause of prostitution (p<0.001). S46 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Conclusion here, prostitution was dependent on substance abuse. It cannot be exactly specified that substance abuse underlies prostitution or vice versa. However, it is clear that substance abuse is prevalent among prostitutes and has many social vile consequences. Therefore, diagnosis and cure of such groups need immediate undertaking Keywords Prostitution, Substance Abuse, Women. The Impact of Cognitive Therapy on Mindfulness in Women Prisoners Anger Management North Khorasan Mahin Hamidi1, Seyed Kaveh Hojjat2, Arash Akaberi3, Mehdi Esmaeili4 1. M.A. of Clinical Psychology, Addiction and Behavioral Science Research Center, Bojnurd 2. Assistant Professor of Psychiatry, North Khorasan University of Medical Sciences. Addiction and Behavioral Sciences Research Center. Bojnurd.Iran 3. B.A. of Clinical Psychology, Addiction and Behavioral Science Research Center.Bojnurd 4. MA.Student Clinical Psychology, North Khorasan Prisons. Iran, Bojnourd Background and Aim Women account for about 2 to 9 percent of prison population. Mental health specialists have found that the rate of internalization (depression) and externalization (aggression, delinquency) problems in prisoners is 2 times more than other people. The investigations have indicated that, one of the most important factors of tendency toward drugs is impulsivity and anger. Mindfulnessbased cognitive therapy can decrease many disorders; however there are few researches that investigate the effectiveness of this intervention on anger. So, the objective of this research is to investigate the effectiveness of mindfulness-based cognitive therapy on some groups in terms of anger control in female prisoners who have a history of drug abuse. Methods Among the 200 female prisoners 60 women, who had a history of drug abuse and had aggressive behaviors, were selected in stratified random sampling method, 28 were placed in Intervention group and 32 were placed in control group. The groups were matched in terms of mean age, marital status, education status and the number of children. The therapy was conducted on the basis of mindfulness-based cognitive therapy in the Intervention groups. The experimental group was trained during 8 weekly 2-hour sessions and the control group didn’t receive any training. The participants were evaluated in two steps: pretest and post test. We used semi-experimental test-retest method to analyze the data. Results Mindfulness-based cognitive therapy significantly decreases in anger, so that Mindfulness-based cognitive therapy decreases the items’ mean (externalization 3.6, internalization 6.0, anger state 14.5, and anger attribute 9.6). It also has increased the means of anger externalization control (-4.9) and anger inter- nalization control (-7.1). The mean of anger index in the experimental group decreased 21.6 units, while in the control group it increased 3.0 units. It is an indicative of the intervention effectiveness. Conclusion The results of the present research showed that Mindfulnessbased cognitive therapy decreases different items of anger in externalization, internalization; anger state and anger attribute aspects in female prisoners. The more mindfulness training people receive, the less they express anger, hostility, and verbal aggression. Training people to pay more attention to the present (mindfulness), decreases their impulsive behavior. As such, our intervention exerted more control on anger externalization and anger internalization in male prisoners. Anger expression, whether in its externalized form that leads to damages to themselves and others, or in internalized form that leads to psychological problems such as depression. can be controlled anger by training mindfulness skills such as nonjudging, patience, beginners mind, non-striving, acceptance and letting go. Keywords Cognitive Therapy on Mindfulness, Anger Management, Women Prisoners The Relationship Between the Personality Traits and the Life Satisfaction of the Addicts Fatemeh Hashemi1, Alireza Feili 2 1. MSc in Psychology & Counseller of Shiraz Education 2. Assistant Professor in Psychology, pnu, Iran Background and Aim Addiction is a physiological, spiritual and mental disease. It threatens the whole family and society for its destroying character in all aspects of the health status of the person. The aim of the current study is to investigate the relationship between the personality traits and the life satisfaction of the addicts. Methods This study is analytical-descriptive. The statistical society of this study is all addicts who were BEDRIDDEN in “Shourideh Addiction campus” of shiraz city in 1392. The sample is 100 people who were selected VOLUNTARY from the statistical society and were examined by personality 5 neo factors and life satisfaction questionnaires of Professor Edinner. The given datas from the questionnaires were analyzed using SPSS software and Pearson Adhesion coefficient test. Results The results of the Adhesion test for personality traits and life satisfaction showed that there is negative significant relationship only in psychoneurosis and life satisfaction aspect of the lives of addicts. In another word, increasing mental annoyance lowers the life satisfaction of addicts. But there is no significant relation in other personality traits with life satisfaction. Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S47 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Conclusion There is Significant relationship between personality traits and life satisfaction Keywords Life Satisfaction, Personality Traits, Addicts, Psychoneurosis. The Comparison of Family Emotional and Training Environment, and Style of Reaction to Problems in Drug Consumer and Non-Drug Consumer Adolescents Hajar Falahzade1, Ramin Hashemi2 1. PhD, Department of Counseling, Faculty of Psychology and Educational Sciences, Shahid Beheshti University, Tehran, Iran 2. M.A Student in Family Counseling, University of Tehran, Tehran, Iran Background and Aim Introduction: the family shapes behavioral model in adolescents, and obviously predispose many behavioral decisions in them. Interaction between adolescent’s characteristics and changes with family environment will lead to strong effect on health and high risk, traumatic behaviors. The present study has been done in order to comparison of family emotional and training environment and style of reaction to problems in drug consumer and non-drug consumer adolescents. Methods Method: in this descriptive study, 105 adolescents (51 individuals drug consumer who living in Correction and Rehabilitation Center of Tehran and 54 normal student, with 13 to 18 years old range) were selected by purposive sampling method whom responded to the demographic and scholarship questionnaires. Results The Pierson Chi-square Exact significance test shows that there is a significant difference between these two groups in father and mother’s behavior with their children, parents’ behavior with each other, discriminating between children by parents, parents’ marriage statues, reaction to problems, and select consultation figure. Also the Pierson Chi-square significance test shows that there is a significant difference between these two groups in family emotional climate. Conclusion Conclusion based on the findings, it seems that any failure in behavioral modeling and Psychological conditions in the family will lead to traumatic effect on adolescents behavior and facilitates traumatic, high-risk behaviors such as drug consume in them. Keywords Family emotional and training environment, style of reaction to problems, discriminating between children, drug consumer adolescents The Relationship between Quality of Life and Depression, Anxiety, and Stress in members of Narcotics Anonymous and the Addicts undergoing Methadone Maintenance Treatment Ramin Hashemi1, Mansureh Hajhosseini2 1. M.A Student in Family Counseling, University of Tehran, Tehran, Iran 2. Ph.D, Department of Education and Counseling, Faculty of Psychology and Educational Sciences, University of Tehran, Tehran, Iran Background and Aim Introduction: In addition to abstinence from drug use in addicts, the outcomes of addiction treatment are also taken into consideration. Quality of life is one of the outcomes of the therapeutic methods which are delivered to harmed individuals and it is considered as one of the effective factors in preventing the relapse to drug use. The present study was performed with the goal of determining the role of life quality in predicting the depression, anxiety, and stress in members of Narcotics Anonymous (NA) and addicts who were undergoing the Methadone Maintenance Treatment (MMT). Methods In this descriptive study, 235 men (116 individuals from NA group, and 119 individuals from MMT group) with age of 20 to 45 years were selected from Shahrekord City through purposive sampling, and they responded to the Quality of Life Questionnaire (SF-36), and Depression, Anxiety, and Stress Scale (DASS-42). Results Pearson Correlation Coefficient revealed the significance of life quality dimensions with depression, anxiety, and stress. The results of regression analysis also showed that respectively, the dimensions of general health (beta = -0/49), emotional health (beta = -0/23) and physical pain (beta = 0/16) determined 57% of the variance in depression (p <0/01 ); and the dimensions of physical pain (beta = 0/28), emotional health (beta = -0/28) and physical limitations (beta = -0/19) determined 35% of the variance in anxiety (p <0/0005); and the dimensions of physical pain (beta = 0/28), emotional health (beta = -0/22), and general health (beta = -0/19) determined 32% of the variance in stress (p <0/0005). Conclusion It seems that the increase in the level of life quality as the outcome of participating in NA or MMT groups, leads to more positive outcomes in depression, anxiety, and stress and it can prevent the relapse to drug use. Keywords Quality of life, Depression, Anxiety, Stress, Narcotics Anonymous, Methadone Maintenance Treatment Methadone complication: Comparing Tablet and Syrup Formulations Soheil Hassanipour Azgomi1, Seyed Abbas Motevalian2, Leila Ghalichi3 1. Tehran University of Medical Sciences 2. Iran University of Medical Sciences 3. Iran University of Medical Sciences S48 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Background and Aim Medical complication is common in patients who take methadone maintenance treatment (MMT).This study was conduct to compare the characteristics of methadone complication between syrup and tablet formulation. Methods Subjective Opiate Withdrawal scale (SOWS) questionnaire was used to measure the side effects of treatment in patients. Of the 60 people for a week in the case of complications were asked questions. The response rate in this study was 91 %. Results Gastrointestinal complications were most common complication among participants. Statistical analysis showed that this effect in those receiving methadone syrup was greater than those receiving Tablet (p=0.025). There was no significant different between drug dose and incidence of complications. Conclusion Due to the high rate of gastrointestinal symptoms in the recipients of the syrup, the necessity of preventive activities before starting maintenance treatment must be recommended. Keywords Methadone, Complication, Tablet, Syrup Effectiveness of Group Therapy Based on Acceptance And Commitment Therapy(ACT) on The Co-dependency of A Group of the mothers of addicted individuals Hamid Hassanpour1, Ali Farhoudian2, Elnaz Zakeri3 1. MD in Family Counseling, University of Social Welfare Sciences, Tehran, Iran. 2. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 3. MD in Family Counseling of University of Tehran, Iran, elnazzakeri@yahoo.com Background and Aim Introduction: Co-dependency not only is the most prevalent addiction but only becomes the “basis” of what all the other addictions and Obsessions results from it. There is not a good management for it so far. Aim: the aim of the present research is to study the effectiveness of therapy based on Acceptance and Commitment Therapy (ACT) on reducing co-dependency of the mothers of addicted individuals Methods Method: the present research is semi-experimental research with pre-test and post-test together with control group. The research population includes 48 of the co-dependent mothers of the addicted individuals in Tehran which have been selected with the use of availability sampling method. Then with Random assignment half of them (24) have been allocated to experimental group and the other half (24) have been allocated to the control group. Research instrument: co-dependent questionnaire (CODI). For data analysis covariance test has been used. Results Findings: the results indicate that there is a significant difference between the experimental and control group in terms of the overall score of co-dependency (P<0.001). Conclusion Conclusion the findings of this research regarding the effect of group Psychotherapy based on acceptance and commitment (ACT) on reducing co-dependence of the mothers of addicted individuals that with accepting the feelings and accepting their real self and reconstructing and Strengthening efficient values and committing to performing them, co-dependence of the mothers of addicted individuals have shown a significant reduction comparing to the period before the therapy. Keywords Co-Dependence, Acceptance and Commitment Therapy Perceived Social Support in Families with Addicted Member Mohammad Heidari1, Hamideh Mancheri2, Mansureh Ghodusi3 1. Faculty Member, School of Nursing and Midwifery, Shahr-e- Kord University of Medical Sciences, Shahr-e- kord, Iran 2. MSc Degree in Nursing, School of Buieh Nursing and Midwifery, Golestan, University of Medical Sciences, Golestan, Iran. 3. Faculty Member, School of Nursing Burojen, Shahr-e- Kord University of Medical Sciences, Shahr-e- kord, Iran. Background and Aim Addiction is a psychosocial, physical problem that because of the progressive nature on existence dimension is a risk for health of addict person and affected on family function. However, it seems that social support for families in this status causes improvement and adjustment. Based on this study was to examine relation between psychosocial problems with perceived social support in families with addicted member. Methods This research study was descriptive that on 1391, 400 first degree family members of the addicted people were selected by randomly sampling. Questionnaire of Northouse social support were the tool for data collection. For data analysis, SPSS version 16 and Fisher test, chi-square test was used. Results The results showed that most subjects (70.3%) displayed moderate levels of perceived social support. relevance perceived social supports with sex (p <0.001), family ratio (p<0.001) and employment status (p=0.003) were positive significantly but relevance perceived social support and age, marital status and educational level were not significantly. Conclusion Because of the high perceived social support had main role on opposite and better adaptation with stressor, nurses can by creation supportive groups and increase level their knowledge improvements quality of life on the all dimension in families with addicted member. Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S49 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Keywords Social Support, Family, Rehabilitation Center Emotion Dysregulation as a Mediator between Attachment Styles and Suicide Attempt in Patients with Substance Use Disorders Masume Heidari1, Seyed Hossein Modjtahedi2, Mojtaba Habibi3 1. Masters In Clinical Psychology, Shahid Beheshti University Of Medical Science, 2. Assistant Professor,Clinical Psychology Department, Shahid Beheshti University Of Medical Scienc, 3. Assistant Professor, Family Research Institute, Shahid Beheshti University Background and Aim Insecure attachment is discussed as a primary factor in emotion dysregulation and dysfunctional behaviors such as suicide and substance abuse. The purpose of this study was to investigating the effects of emotion dysregulation mediating between insecure attachment and suicide and between insecure attachment and substance use. Methods 425 participants completed Experiences in Close RelationshipsRevised (ECR-R) and Difficulties of Emotion Regulation Scale (DERS) and the 20-item Toronto Alexithymia Scale (TAS-20). A confirmatory factor analysis and Structural equation modeling through AMOS-22 software were used for data analysis. Results Findings indicated that insecure attachment was significantly mediated by emotion dysregulation on suicide and substance abuse. Conclusion Emotion dysregulation fully mediates the association between attachment avoidance and suicide and substance use, and between attachment anxiety and suicide and substance use. Attachment anxiety has a little direct effect on suicide and substance use. Thus, insecure attachment related to suicide and substance use through emotion dysregulation. These findings will be useful clinical implications in the prevention and treatment. Keywords Attachment, Emotion Dysregulation, Suicide, Substance Use Emotion Dysregulation in Substance Use Disorders and Suicide Masume Heidari1, Seyed Hossein Modjtahedi2, Mojtaba Habibi3 1. Masters In Clinical Psychology, Shahid Beheshti University Of Medical Science, 2. Assistant Professor,Clinical Psychology Department Shahid Beheshti University Of Medical Scienc, 3. Assistant Professor, Family Research Institute, Shahid Beheshti University Background and Aim Despite the emphasis on the role of substance use disorders (SUD) in suicide attempt (SA), no studies have examined difference between the rates of both. Research indicates emotion dysregulation heightens among SUD and SA. This study investigate could the emotion dysregulation explain why only a small number of addicts who committed suicide. Methods 425 participants completed Difficulties of Emotion Regulation Scale (DERS) and the 20-item Toronto Alexithymia Scale (TAS20). A multivariate analysis of variance through SPSS-22 software were used for data analysis. Results Findings indicated that suicide attempt and substance use compared to control group have more difficulties in emotion dysregulation. SA patients with or without SUD have no significant differences in emotion dysregulation items (P>1). Emotion dysregulation was significant differences between SUD patients with a history of SA and no SA (P<0.01). Conclusion Severe difficulty in emotional regulation explain as well as the differences between those who have a history SA in patient with substance use disorders. Accordingly, Increase emotion dysregulation whether or not the substance use disorders is more likelihood of suicide attempts. The clinical implications of these findings will be useful in the prevention and treatment seeking. Keywords Emotion Dysregulation, Suicide, Substance use Effectiveness of Social Skills Training on Emotional Intelligence of People with Substance Abuse Mona Heidaripour1 1. MA General Psychology, Ferdowsi University of Mashhad Background and Aim The present study investigated the impact of social skills training on emotional, people with substance abuse has performed the city of Mashhad. Methods Research method was quasi – (using pretest- posttest control group design(.The statistical society of study contain of all people with substance abuse in Addiction Treatment Clinic of Mashhad, That after initial screening, among which 30 selected that were most insufficient in terms of social skills and emotional intelligence ,using random assignment method were placed in two experimental and control placebo groups Was used to collect data for research from questionnaire of social skills inventory of Regio, Bar –On questionnaire .Data were analyzed using multivariate analysis of covariance. Results Data analysis showed Social skills training was lead to performance difference between the study group in stress ma nagement(F(1,22)=8/69,0/01<0/05) Interpersonal relations (F(1,22)=13/61,0/01<0/05) Adaptability(F(1,22)=20/47,0/01<0/05) Intrapersonal relations(F(1,22)=42/02,0/01<0/05) general mood(F(1,22)=13/55,0/00<0/05) and promote emotional intelligence in people with physical disabilities (P< 0/05). S50 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Conclusion Considering the components of emotional intelligence, social skills social skills training leading to increased levels of emotional intelligence. The greatest influence on component part to the interpersonal, public mood, Interpersonal relationships and compatibility has had minimal effect on the components of stress management. Keywords People with Substance Abuse, Emotional Intelligence, Social Skills Training The Impact of Alcohol Abuse on Required Dose of Opioid Agonist in Substance Dependent Patients Treated on Maintenance Program: North Khorasan Addiction Study Hojjat Seyed kaveh1, Ebrahim Golmakanie2, Hojjat Seyed kaveh3, Mina Norouzi khalili4, Sorour kazemi5 1. Assistant Professor of Psychiatry, North Khorasan University of Medical Sciences. Addiction and Behavioral Sciences Research Center, Bojnurd, Iran 2. Assistant Professor of Anesthesia, Mashhad University of Medical Science. Addiction and Behavioral Science Research Center, Bojnurd, Iran 3. Assistant Professor of Psychiatry, North Khorasan University of Medical Sciences. Addiction and Behavioral Sciences Research Center, Bojnurd, Iran 4. Assistant of Community Medicine, Mashhad University of Medical Sciences. Department of Community Medicine, Mashhad, Iran 5. MA Student of Clinical Psychology, North Khorasan University of Medical Sciences. Addiction and Behavioral Sciences Research Center, Bojnurd, Iran Background and Aim Background: Research over the past two decades has shown that alcohol abuse in patients treated with opioid agonists such as methadone may affect the healing process through several mechanisms. One of the main challenges is the interactions between alcohol and methadone and other opioid agonist drugs. Purpose of this study was to evaluate the impact of alcohol abuse on dose of methadone and other agonist drugs Methods We conducted a cross sectional survey of 7133 patients sampled from” North khorasan addiction rehabilitation clinics database” in 2013.The method of sampling was multi steps sampling, Stratified-Cluster Sampling. Data was collected using an intervieweradministered questionnaire, which included socio-demographic, and substance use characteristics and types of opioid agonist drug and dose of drugs such as methadone, bupronorphine and opium tincture in maintenance treatment and concurrent use with alcohol. Chi was used for comparison of results. Statistical analyses were performed using the SPSS 22 software. Differences were considered significant at P<0.05. Results Results showed that 66.6% of patients with concurrent use of alcohol treated on methadone maintenance program, 23.3%treated with opium tincture and 9.9% treated with bupronorphine. Mean dose of methadone in alcohol use group was 68 mg and 65mg for non abuser group. This difference was not significant (p=0.541). . Mean dose of opium tincture in alcohol use group was 21.9 mg and 18.8 mg for non abuser group. This difference was significant. Mean dose of bupronorphine was not significantly difference in tow groups. Conclusion It appears that issue of alcohol abuse most be consider in selection of patients for treatment by opium tincture. Keywords Alcohol Abuse, Dose of Drug, Methadone, Opium Tincture Efficacy of Training Base on Choice Theory on Marital Satisfaction of Spouse Addicted Patients Treated on Methadone Maintenance Program Hojjat Seyed kaveh1, Hojjat Seyed kaveh2, Ebrahim Golmakani3, Alieh Saadatmand4, Mina Norouzi khalili5, Ebrahim Ebrahimi Sani6 1. Assistant Professor of Psychiatry, North Khorasan University of Medical Sciences. Addiction and Behavioral Sciences Research Center, Bojnurd, Iran 2. Assistant Professor of Psychiatry, North Khorasan University of Medical Sciences. Addiction and Behavioral Sciences Research Center, Bojnurd, Iran 3. Assistant Professor of Anesthesia, Mashhad University of Medical Science, North Khorasan University of Medical Sciences, Addiction and Behavioral Sciences Research Center, Bojnurd, Iran 4. MA of Family Consueling, Islamic Azad University, Ghuchan Branch, Ghuchan, IRAN 5. Assistant of Community Medicine, Mashhad University of Medical Sciences. Department of Community Medicine, Mashhad, Iran 6. MSC in Counseling and Guidance, After Prison Leaving Care Center, North Khorasan, Bojnourd, Iran Background and Aim Marital satisfaction is an important aspect of family life that shapes people’s mental health and happiness. It is associated with less physical illness, less depression and less psychological distress .The substance abuse are longitudinally related to problems in intimate relationship functioning. Recent studies have reported lower levels of marital satisfaction among addicted couples marital quality is one of the important aspects of family life that shapes people’s marital satisfaction. Substance abuse in long-term cause problems in intimate relationship and sexual functioning. This study aimed to examine the effectiveness of cognitive therapy based on learning of choice theory on marital satisfaction of spouse of substance dependents. Methods The statistical population of this study composed of thirty patients (and their spouses) who treated on methadone maintenance program in bojnurd city. We used an Enrich questionnaire to evaluate marital satisfaction. Spouses of subjects randomly assigned to intervention and control group. The interventions were performed in 90-minute individually sessions over 8 week. The content of the training sessions was obtained from the Choice theory a new psychology of personal freedom compiled by William Glasser. We used ANOVA, independent T, and chi-square for data analysis. Data was analyzed using SPSS (17.0). Results The demographic indicators such as age, length of marriage, education, and type of drug were studied to determine the difference of these variables between the two groups. The main and standard deviation of marital satisfaction scores were 113.33±27.77 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S51 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall and 114.53±19.98 in pretest and 114.13±27.21 and139.73±18.98 in posttest, respectively. According to ANOVA test there was significant difference in marital satisfaction scores between pre- and post-test (F=72.76 and P=0.0005).The results of t-test showed that there was significant difference between control and experimental groups in marital satisfaction variable (t = -8.27 and P= 0.0005). Also, Chi-square test showed that there was no significant difference between control and experimental groups in rate of relapse of addiction (P=0.64, x2= 0.24). Conclusion The results of current study showed that the learning choice theory is effective in increasing marital satisfaction of couples. Marital problems can seriously impact on process of treatment and need to special attention in methadone maintenance patients. Keywords choice theory, marital satisfaction, spouse, drug dependents The Relationship between Emotional Intelligence and Divorce in Drug Dependent men 2 3 Background and Aim Many factors go hand in hand at the occurrence of divorce, that leading to the breakdown of the family. One of the recognized causes of divorce is the issue of drug addiction in either one or both of the couples. Research carried out in Iran shows that about fifty to sixty percent of divorce cases are either directly or indirectly related to drug addiction. Although most studies have referred to the issue of drug addiction as a general cause for divorce, less attention has been given to indicating which aspect of drug addiction’s side effects and harms have a greater influence on the spouse’s decision for divorce. Evidence suggests that emotional intelligence is involved both in the incidence of drug addiction and the occurrence of divorce Methods Results Results from this study showed that the overall scores for emotional intelligence in individuals with a history of divorce, regardless of being drug dependent or non-dependent, were significantly lower than the group without a history of divorce. After considering both addiction and divorce variables, individuals were divided into four groups. Comparison of the groups revealed that emotional intelligence scores in non-addicted individuals with a history of divorce are significantly lower than the non-addicted group without a history of divorce. However, in addicted individuals with a history of divorce, only the component of emotional intelligence self-control showed a significant difference compared to the addicted group without a history of divorce. Conclusion Hojjat Seyed kaveh , Mina NoroUzi khalili , Mohammad Khajedaluee , Reza Erfanian Majid4, Hojjat Seyed kaveh5 1. Assistant Professor of Psychiatry, North Khorasan University of Medical Sciences. Addiction and Behavioral Sciences Research Center, Bojnurd, Iran 2. Assistant of Community Medicine, Mashhad University of Medical Sciences. Department of Community Medicine, Mashhad, Iran 3. Associate Professor of Community Medicine. Department of Community Medicine, Mashhad University of Medical Sciences. mashhad. Iran 4. Associate Professor of Infectious Diseases. Department of Community Medicine, Mashhad University of Medical Sciences. Mashhad. Iran 5. Asistant Professor of Psychiatry, North Khorasan University of Medical Sciences. Addiction and Behavioral Sciences Research Center, Bojnurd, Iran 1 mographic information checklists were completed for all groups. Qualitative variables were compared between the four groups using chi-square tests and Quantitative variables were compared using ANOVA. Between-group differences were analyzed using the Tucky test. In addition, data were analyzed using SPSS, version 11.5. Statistical significance was set at p<0.05 for all calculations. This cross-sectional study was carried out in the city of Bojnurd (North Khorasan province, Iran). Two-hundred men were enrolled in four study groups. First group, which was also our case group, included drug-dependent men who had a history of at least one divorce. The second group in this study consisted of married drug dependent men with no history of divorce. This group of individuals made up our first control group. The third group was nondrug-using men who had a history of at least one divorce. These individuals made up our second control group. Fourth group in the study were non-drug-using married men with no history of divorce. The Shrink Emotional Intelligence Questionnaire and de- The issue of drug dependency and divorce are not only related to socio-economic effects on the family, but also linked to emotional intelligence and its components such as self-control. Thus, psychotherapeutic programs for substance dependents should pay special attention to this issue. Keywords Emotional Intelligence, Divorce, Drug Dependents A Comparison of Demographic Characteristics of Men and Women Under Agonist Maintenance Treatment in North Khorasan Province Hojjat Seyed kaveh1, Ebrahim Golmakanie2, Reza Erfanian Majid3, Mohammad Khajedaluee4, Mina Norouzi khalili5, Hojjat seyed kaveh6, Ebrahim Ebrahimi Sani7 1. Assistant Professor of Psychiatry, North Khorasan University of Medical Sciences. Addiction and Behavioral Sciences Research Center, Bojnurd, Iran 2. Assistant Professor of Anesthesia, Mashhad University of Medical Science. Addiction and Behavioral Science Research Center, Bojnurd, Iran 3. Associate Professor of Infectious Diseases. Department of Community Medicine, Mashhad University of Medical Sciences. Mashhad. Iran 4. Associate Professor of Community Medicine. Department of Community Medicine, Mashhad University of Medical Sciences. Mashhad. Iran 5. Assistant of Community Medicine, Mashhad University of Medical Sciences. Department of Community Medicine, Mashhad, Iran 6. Assistant Professor of Psychiatry, North Khorasan University of Medical Sciences. Addiction and Behavioral Sciences Research Center, Bojnurd, Iran 7. MSC in Counseling and Guidance, After Prison Leaving Care Center, North Khorasan, Bojnourd, Iran Background and Aim Introduction: Drug addiction is one of the four crisis threatening mankind, alongside environmental, nuclear, and population crisis. Iran is among the countries involved with the problem of drug addiction due to the fact that it neighbors Afghanistan, the world’s largest producer of opium and heroin. Although significant progress has been made in understanding the effective causes and factors of drug addiction, less attention has been given to the S52 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall issue of addiction in women. Moreover, therapeutic interventions are mostly devised based on the characteristics and needs of men. This is while studies indicate that drug addiction in women is associated with greater physical damage and more serious social problems. 3. Iran.Shahre-Kord- University of Medical Science ¬- Specialty and Subspecialty Polyclinic Imam Ali (AS) – BSc laboratory Science, Tel:0381-2240281-09131833651-Email: Mheidari111@yahoo.com 4. Shahre-Kord- University of Medical Science.Godal cheshmeCorresponding Author: MSc-Medical Education and BSc Nursing-0381-3349560 – 09131845609- Email: Ayazi_z56@yahoo.com Background and Aim Methods This is a cross-sectional study carried out in the year 2013. All individuals under treatment in North Khorasan’s addiction treatment centers were evaluated through interviews conducted by the centers’ psychologists. Items on the checklists were marked off to record demographic and socio-economic information as well as methods of substance abuse, type of abused substance, and other related items. Chi-square test was used for comparing qualitative variables between the two genders. The t-test and Mann Whitney test were used for comparing quantitative variables in proportion to the distribution of the variable. Statistical significance was set at p<0.05 for all computations. Results This study was carried out on 7342 substance-abusing individuals receiving treatment in methadone maintenance treatment centers. Out of this number, 82.5% were men and 17.5% were women. 65.4% of the surveyed drug addicts lived in urban areas while 34.6% lived in rural areas. In addition, 87.5% of the patients under study were married, 6.6% single, and 5.9% divorced. 95% of the patients had a history of opium use, 14% heroin and crack use, and 2.8% methamphetamine use. Just as can be seen in the distribution of the educational level of individuals under study, 28% of the drug-addicts were illiterate. This ratio is considerably higher in the female population (60.6%). Also, over half of the examine individuals had lower than middle school education (56.6%). This ratio is 81.4% in women Conclusion It appears that there are obvious differences in the demographic pattern of referrals to maintenance treatment centers and other groups of patients with drug addiction. This difference is more pronounced in terms of age, ration of female to male referrals, and type of abused substance. Results indicate that retention in maintenance treatment using methadone and tincture of opium has increased in rural populations, especially among opium using rural women. As time passes, the proportion of opium dependent patients to heroin and crack using patients is increasing in maintenance treatment centers. This gradual change in the target group calls for special attention. Keywords Demographic Characteristics, Drug Dependence, Maintenance Treatment Professional Nursing Roles in Dealing with Social Problems in Addected Patient Sayed Jalil Hoseini Irani , Homeira Mohamadi , Mojtaba Heidari , Zahra Ayazi 1. Iran, Shahre-kord- University of Medical Science. MSc NursingTel: 0381-3349560 – 09134133685- Email: jalil_irani_s@yahoo.com 2. Shahre-Kord University of Medical Science, BSc NursingMobile:09131848637-Email: mohamadih7778@yahoo.com 1 2 3 4 In the past, the role of nurses was in providing patient care and providing comfort during nursing tasks. But modern nursing require different skills and knowledge in order to keep pace with the changes and improvements to pay for their roles. One of the major changes or social problems, the prevalence of addiction and its complications. Which inevitably affect the nursing profession in all aspects. Methods The type of This paper is a describe – library article that is set in review. It uses scientific research – articles and information of search engine google scholar and magIran and database and books in this field that are analyzed and conclusions are discussed. Results One of the most important roles in dealing with the patient’s nurse, caring role is to facilitate the recovery process. However, because of addicted patient due to physical and physiological condition, require special cares, Nurses must specify his needs and develop care processes. The family and social support for patients addicted to drugs, lost And nurses needs the skills necessary to play a supporting role for him/her. Integral part of the nurse’s role is education addicted patient who is on admission and at discharge And nurses rely on it to communicate with addicted patients to facilitate and complete the recovery process. In addition to his managerial role, nurses coordinate other activity of health care team members to Addiction recovery process chain is not disrupted. Conclusion What is certain addiction in our society today is considered as one of the social problems and promote the professional skills of health staff, is inevitable. Thus Health nurses as the main link has to enhance their skills and their roles in dealing with drug addicts. Keywords Professional Role, Nursing, Social Problems, Addicted Opium Withdrawal and Some Blood Biochemical Factors in Addicts’Individuals Seyed Mostafa Hosseini Zijoud1 1. Clinical Research Development Unit, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran Background and Aim One of the common misinterpretation be- liefs in some societies (especially eastern communities) is the using of opium can reduce serum glucose and lipids. Opium is a derivative from a plant family called Papaveracea and contains almost 80 types of alkaloids. Drug addiction causes physiological de-pendency and Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S53 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall its withdrawal lead to some disorders. The aim of this study was to determine the effects of opium consumption and its withdrawal on some blood biochemical factors in addicted people. Methods We enrolled fifty-six opium addicted people accord- ing to the especial criteria to this study. Biochemical blood parameter levels such as fasting blood sugar (FBS), urea, Creatinine (Cr), Aspartate transaminase (AST), Alanine transaminase (ALT) and Alkaline phosphatase (ALP) enzymes levels were measured and urine analysis was also performed before and 3 months after withdrawal. Data were analyzed by us- ing SPSS software version 18 and a P < 0.05 was con- sidered as significant. Results Our finding showed that opium withdrawal reduces FBS and increases AST but these changes were not significant. Never- theless opium withdrawal significantly increased blood urea level (P < 0.0001). We didn’t find any sig- nificant difference in Cr, ALP, AST and Urea specific gravity (SG). Conclusion According to the results of the current study we can concluded that opium in- creases FBS, which is in contrast to the most previous studies and withdrawal has opposite effects. Keywords Opium, Addiction, Withdrawal, Fasting Blood Sugar (FBS) A Comparison of Sensation Seeking, Problem- Solving Styles and Coping Stress Strategies in Substance Abuser and Normal Persons Seyedeh Zahra Hosseininasab Astaneh1, AbbasAli Hossein Khanzadeh2, Iraj Shakerinia3 1. Islamic Azad University Science and Research Branch,Guilan, Iran 2. The University of Guilan 3. The University of Guilan Background and Aim The aim of this study is the comparison of sensation seeking, problem- solving styles and coping stress strategies in substance abuser and normal persons. Methods The research method was causal-comparative. The statistical population consisted of all substance abusers and normal ones that 100 members of both groups were selected as a sample by convenient sampling. They completed the Arentt Inventory of Sensation Seeking (1992), Problem-Solving Styles Scale (Cassidy & Long, 1996) and Moos & Billings Coping Stress Strategies Scale (1981). Results The results showed that there was significant differences between sensation seeking and sensation novelty and intensity subscales, adaptive problem- solving styles (Creative, Confidence, Approach), non-adaptive problem- solving styles (Helplessness, Control, Avoidance), coping stress emotion-focused and problemfocused strategies of substance abusers and normal persons. Conclusion Findings of this research show the important role of some of the personality variables such as sensation seeking, problem- solving styles and coping stress strategies that correlate with substance abuse disorders in the people. Keywords Sensation seeking, problem- solving, coping stress strategies, substance abuse An in Vivo Study: The Effect of Methamphetamine on Xanthine Oxidase Activity and NO Levels Rats Alireza Hosseinzade1, Mohammad Hossein Tanipour2, Faezeh Sadrabadi Haghighi3, Mohammad Soukhtanloo4, Seyed Isaac Hashemy5 1. Department of Biology, Faculty of Science, Science and Research Branch of Islamic Azad University Kurdistan, Iran 2. Department of Medical Biochemistry, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran 3. Department of Medical Biochemistry, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran 4. Department of Medical Biochemistry, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran 5. Department of Medical Biochemistry, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran Background and Aim Methamphetamine is part of a family of drugs more generally known as “amphetamines” that is also called “glass” in Iran. The members of this family are synthetic stimulants, similar to the naturally occurring stimulant ephedrine and hormone adrenalin. In recent years the pattern of abuse changed from opioids to industrial drugs specially methamphetamine. The abuse of methamphetamine is associated with a range of mental health problems; but along with these problems, the physiological and biochemical effects of the “glass” are an interesting field for researchers. Xanthine oxidase catalyzes the hydroxylation of hypoxanthine to xanthine and then to uric acid. In mammalian tissues, xanthine oxidase is found predominantly in the liver and intestine. Nitric Oxide is a one of reactive oxygen species (ROS) which is considered as an oxidative stress marker. We aimed to survey the effect of “glass” on serum and tissue level of NO and Xanthine oxidase in rats. Methods The “glass” was obtained from Khorasan Razavi Drug Control Coordinating council. The assay to measure Xanthine oxidase is based on a multistep enzymatic reaction in which xanthine first produces H2O2 during oxidation of hypoxanthine. In this method rats received various amounts of methamphetamine injections from 2.5 mg/kg to 10 mg/kg, and divided in 3 groups, first group after 3 days, the second one after 13 and the third group after 40 days were killed and tissues were disparted. All experiments perform on brain and liver homogenization and serum. Xanthine oxidase activity was analyzed by using Cayman assay kit with a highly fluorescent compound “resorufin” which produced from react of H2O2 and ADHP (10-acetyl-3,7-dihydroxyphenoxazine). S54 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Results In this research, Xanthine oxidase activity was investigated in the brain, liver and serum of methamphetamine received rats, but the results did not show any difference between time periods and different doses compared to control groups. NO level in serum increased significantly specially in sub-acute and chronic groups. This raising occurred dose dependently particularly in high doses including 7.5mg/kg and 10mg/kg. Conclusion Methamphetamine is known as a destructive industrial drug which its effects were evaluated via common oxidative-stress markers such as Protein Carbonyl, MDA and NO. In this study NO level as a current marker and Xanthine oxidase activity as unusual marker were examined in brain and liver tissues and serum. Xantihine oxidase activity in both liver and brain didn’t show any difference with control groups; it seems methamphetamine doesn’t have any effect on the activation process of xanthine oxidase. However, according to prior researches about Methamphetamine, our results showed significantly raising amount of NO in serum. We suggest using of more samples and various doses in next studies to obtain more confident results. Keywords Methamphetamin, Xanthin oxidase, NO Ebrahim Ijabi1, M Karimlo2, M Rahgozar3, M Tavakoli4 1. University of Social Welfare & Rehabilitation Sciences, Tehran, Iran 2. University of Social Welfare & Rehabilitation Sciences, Tehran, Iran 3. University of Social Welfare & Rehabilitation Sciences, Tehran, Iran 4. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran This paper aims at evaluating and selecting the most suitable detoxification method among the following four Methods Thirty experts considered the four detoxification methods and rated the 7 criteria on a 1 - 9 scale –basis. Then, after making a decisionmaking matrix, the four methods were prioritized and the best was chosen through the next six-stage if the TOPSIS technique. Results The replacement method was closer to positive criteria and more distant from negative ones in compare with other methods (Ci=0,653446). according to these findings, the replacement method turned out to be the most suitable method of detoxification. Addiction, Addiction Treatment, TOPSIS, Detoxification Background and Aim This study was aimed to determine the prevalence of drug use among Prisoners who sentenced for drug trafficking that referred to Fars Legal Medicine Center. Methods In this cross-sectional descriptive study, during 5 years (20092013)721 prisoners who have committed drug trafficking crime and referred to legal medicine in Fars province to check the status of tolerated sentence were examined .We used drug use prevalence questionnaire. Finally, the data were statistically analyzed through Spss19 software and we used chi-square test to find relation between prevalence of drug use and drug trafficking crime. The results show that 9.8% (71) were female.The mean and standard deviation of age for the cases was 38/12 ± 81/29 years. The term of imprisonment of 16% (115) were over 15 years and 27% (195), 10 to 15 years and 31% (223), 5 to 10 years and 26%(188) were less than 5 years. The results also show that 69 %( 497) of prisoners have been used drug before. The relation sheep between drug use and drug trafficking crime was meaningful (p= 0/000). 46% of the prisoners, opium, 27%, heroin, 20%, cannabis and the other have been used Methamphetamine. Conclusion Background and Aim Keywords Fattah Jafarizadeh1, Mohammad Zarenezhad2 1. PhD by Criminal Law and Criminology, Legal Medicine Research Center, Tehran, IRAN 2. MD, PhD by Research, Legal Medicine Research Center, Tehran, IRAN Results Evaluating and Prioritizing Addiction Treatment Methods trough the TOPSIS Technique Conclusion Drug Use Prevalence among Prisoners Who Committed Drug Trafficking Crime Referred to Legal Medicine in Fars Province; 2009-2013 The results of this study demonstrate a significant correlation between drug abuse and drug trafficking crime.so, recommended to reduce the prison population and drug trafficking crime, the country’s more serious addiction preventive programs to be followed. Keywords Drug Trafficking, Prevalence, Drug Use, Prisoner A Sexual Addiction Case Presentation Parisa Jahanloo1 1. Tehran University of Medical Science Background and Aim An educated high social young man came to our clinic complaining of wasting much time in a day more than 3 hours because of Sexual Fantasia;Sexual imagination and thinking with Sexual content mostly Paraphilic thought-masochism.Then he had to watch pornographic movies again with Paraphilic subjects and finally masturbate.2 or 3 times he tried to have a date with a known prostitute who had Sadistic desires.Because of compulsive and sometimes impulsive nature of his thoughts ;we recognized Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S55 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall him as a hyper Sexuality or Sexual Addiction case with obsessiveCompulsive background. According to DSM-5 diagnostic criteria for Sexual Addiction ,our patient had 4 criteria from 5 criteria in part A and all other parts B,C and D. Methods Interview in 8 session lab test-Serum Testosterone was normal Results We found he had a very critic and controller mothert , his father had also Paraphilic desires. He had brought up with a high Discipline manner,had a weak emotional relationship with his parents .Also he had a previouse diagnosis as Asperger. Conclusion A SSRIs started for him- Citalopram 40 mg per day for about 5 month .More than 4 session the therapist talked to him ,using CBT Techniques to know his disorder well.Also some other techniques like deep breathing and relaxation was taught .After about 4 months he had a dramatically decrease in his thought and masturbation less than 15 min fantasies in a day and about one time masturbate in week. Although our case, because of his special personality didn’t engage in many real Sexual contact: but Sexual Addiction can act as a risk factor of STDs ;because of Its Impulsive nature and must pay attention to STDs and do necessary physical examination and lab test. Keywords Sexual Addiction;Impulsive or Compulsive Nature;SSRIs;STDs The Prevalence of Tobacco Use and its Psychological Determinants among Iranian Children and Adolescents: CASPIAN IV Study Mohsen Jari1 1. Child Growth and Development Research Center of Isfahan University of Medicine Background and Aim This study aims to assess the prevalence of tobacco consumption in Iranian children and adolescents and its psychological determinants Methods In this nationwide study, 13486 elementary, secondary and high school students(50.8 % boys, 49.2% girls) were selected by cluster and stratified multistage sampling method from 30 provinces in Iran. The Global school -based Health Survey questionnaire of the World Health Organization ( GSHS-WHO) was used. Results Overall 2.7 % of Iranian children and adolescents (3.49% of boys and1.66% of girls) were current smoker and 5.8% (7.84% in boys and 4.19% in girls) were ever smoker . 3. 0% of urban children and adolescents and 1.2% of rural were current smoker. Also high school students reported higher prevalence of the current tobacco use (6.8%) than secondary (1.46%) and elementary (0.65%) students. A total of 6.5% of urban children and adolescents and 3.8% of rural were ever tobacco user and this figure in elementary, secondary and high school student were 2.1%, 4.55% and 13.3% respectively . The results of this study showed that the average age of the first attempt to tobacco use was12.40±3.39years in all which this figure in boy and girls was 12.31±3.37years and 12.56±3.41 years respectively . entertainment and recreation has been the most prevalent reason of smoking initiation in 2.3 % of Iranian children and adolescents and continuation of use in 2.1% of them . Pleasure is stated as the second reason of smoking initiation among 1.6% of Iranian children and adolescents and reason of use continuation in 1.5% of them. Conclusion Conclusion The prevalence of tobacco use among Iranian children and adolescents in early ages and use of these products as a way of recreation and pleasure suggest that culturally-appropriate educational and cultural programs should be planned and implemented to prevent this harmful habit. . Keywords Cigarette, Children and Adolescents, Tobacco, Iran Reflections of a Homeless Population’s Lived Experience With Substance Abuse Seyed Mohamad Hossein Javadi1, Pilevari . A2, Hamed .,M3 1. PHD Student in Social Work, Tehran Welfare and Rehabilitation University 2. PHD Student in Social Work, Tehran Alame University 3. PHD Student in Social Work, Tehran Alame University Background and Aim Substance abuse is recognized as a major health problem among the homeless. People who cycle in and out of homelessness tend to cycle in and out of alcohol and drug abuse. The relationship between substance abuse and homelessness requires that they are treated simultaneously and not independently. Although there is an increase in public interest concerning the homeless population, research on the issues of homelessness has been fragmented and incomplete. Research is necessary to understand substance abuse among the homeless so that prevention and intervention measures can be developed and implemented. The aim of this study was to describe a homeless population’s lived experience with substance abuse and to better understand factors that effect to substance abuse treatment among the homeless. Methods This paper fulfilled by the method of grounded theory. The data were gathered through in-depth interviews with 20 men who participating in Project of rehabilitation of drug user (1393). Data from the interviews were analyzed by theoretical coding. Results Categories that emerged from the data included: experience of rejection from family and friends, traumatic experience, shame, social isolation, hopeless, social apathy. The core category in this investigation was “marginalization” of the homeless addict. Finally in this article we present a paradigm model of marginalization of these groups. Recognizing these categories can assist to S56 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall effective planning, make policy and intervention on addiction and homeless. Conclusion: Keywords Lived Experience, Addiction, Homeless, Experience of Rejection Therapeutic Community Approach is Effective in Improving Self-care Skills, Self-awareness, Assertiveness, Emotion and Hope for Addicts Masome Kadkhodai1,Reza Dastjerdi2, Javad Beheshti Por3 1.Behzistei Organization 2. Assistant Professor of Psychology, University of Birjand 3. Behzistei Organization Therapeutic Community, Emotion Management Skills, Self Care Skills, Assertiveness Skills, Their Skills, Knowledge and Hope. Effectiveness of Cognitive-Behavioral Group Therapy for Anger Management in Reducing the Wife Abuse and Increasing Marital Satisfaction in Patients with Substance Abuse Hurie Karami1, Hamid Khakbaz2, Hamideh Lashgari3, Mohammad Mohammadi4 1. M. A in Clinical Psychology in Allame Tabataba’i university 2. M. A in Counseling 3. M. A in Psychology 4. M. A in Counseling Background and Aim Background and Aim Background and Purpose: The therapeutic community approach is founded on a clear vision of the four terms is related to the disorder, substance abuse, or addiction, recovery, and right living. Addicts socialization, cognitive skills, and emotional and psychological growth are problematic. Improvement of the therapeutic community approach is the change in lifestyle or identity. In the present study we examined the effectiveness of the therapeutic community in promoting life skills and hope people wont pay The impact of this therapeutic approach in the treatment and prevention of relapse to show material. Methods The research method used in this study is a quasi-experimental pre-test-post-test is performed. The population in this study, people referred to a therapeutic community center in South Khorasan Province In the first quarter of 1392 Due to the low volume of sample population, as the sample was used for all statistical population. Given the number of people admitted to 25 people. Questionnaire in order to provide life skills before treatment and after treatment was performed. After collecting the questionnaires, data were entered into the statistical software 16SPSS and were analyzed by paired t-test. Results The results showed that the therapeutic community program on improving management skills, feelings and emotions, self-care skills, assertiveness skills, expertise, knowledge has a positive effect (p ≤ 0/05). However, the results suggest that the therapeutic community is not effective in promoting hope for patients (p> 0/05). Conclusion Keywords It should be noted that one of the factors or trends comeback addicts, And the results of this study can be effective therapeutic community as an agent for the prevention of addiction show. However, hope is one of the basic elements of addiction treatment, during treatment, the role of which should make it more colorful. The aim of the current study was to determine the effectiveness of cognitive-behavioral anger management therapy for reducing wife abuse and increasing marital satisfaction in patients with substance abuse. Methods The design of this study was quasi-experimental and pretestposttest with control group that attending treatment center for drug addiction. Statistical population were all men with substance abuse in Tehran in 2013. 12 patients with drug abuse that showed high levels of wife abuse and their spouses were randomly selected as sample group and replaced in experimental (N=6) and control (N=6) groups. Data were collected by using Ghahhari and colligues Wife Abuse Inventory and Enrich Marital Satisfaction Scale, analyzed by T and ANCOVA. Results Findings indicated that cognitive-behavioral group therapy for anger management significantly reduced levels of wife abuse (p<0/01) and increased marital satisfaction (p<0/05, F: 12/36) in the experimental group compared with the control group. Conclusion Cognitive-behavioral group therapy for anger management is effective in reducing the wife abuse and increasing the marital satisfaction in men with substance abuse. Keywords Cognitive-behavioral therapy, wife abuse, marital satisfaction, substance abuse. Effectiveness of Mindfulness-Based Cognitive Therapy on Reduce Co-Morbid Anxiety in Drug-Dependent Peoples Reza Karimi1, Kobra Mosadegh2, Jaber Abipor3 1. Graduate Student, Clinical Psychology, Allameh Tabatabai University, Tehran 2. Master of Clinical Psychology, Allameh Tabatabai University, Tehran 3. Graduate Student, Rehabilitation Counseling, Allameh Tabatabai University, Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S57 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Background and Aim Nowadays the third wave therapies in psychotherapy instead of challenge with cognitions, emphasizes awareness and acceptance of people’s feelings, emotions, cognitions and behaviors. Recently, there are much discussion about cognitive behavioral interventions “third wave” especially in the area of anxiety and anxiety disorders. The aim of present study is survey the effectiveness of Mindfulness-Based Cognitive Therapy (MBCT) on reduce comorbid anxiety in drug-dependent peoples. Methods This study is semi-experimental with pre-test, post-test and control group. Population, including all of addict’s people referred to Addiction Treatment Center (Taranom) in Tehran that first taken Beck Anxiety Inventory (BAI) of them and among those who had high anxiety, 40 subjects were selected and randomly divided into experimental and control groups consisted of 20 persons. Results A result of covariance analysis shows that mindfulness-based cognitive therapy for people with addiction have significant effect on reducing anxiety. Conclusion Treatment process and the results obtained in this study suggest that mindfulness-based cognitive therapy can be effective in treating anxiety in people with addictions. Keywords Cognitive Therapy, Mindfulness, Anxiety, Addiction The Study of Psychometric Properties of Acceptance and Action Questionnaire – Substance Abuse (AAQ-SA) Javad Karimi1 1. Department of Psychology, The University of Malayer, Malayer, Iran Background and Aim Experiential avoidance and psychological inflexibility have been recently found to be important constructs related to a wide range of psychological disorders and quality of life. Poor psychological flexibility has been shown to relate to clinical problems as well as normative life challenges, and efforts to increase psychological flexibility have correlated with improvements for a variety of psychological difficulties, including substance abuse. This study focused on the validation of the Iranian version of the Acceptance and action questionnaire – Substance abuse (AAQ-SA), which assesses the construct referred to as, variously, acceptance, experiential avoidance, and psychological inflexibility in substance misusing samples. Methods In this cross-sectional study, 113 patients with dependent opioid addiction referred to Addiction Treatment Centers in Esfahan were selected through convenience sampling method. Partici- pants filled out demographic questionnaires, “Acceptance and action questionnaire – Substance abuse “, “Acceptance and Action Questionnaire edition 2”, “Rosenberg Self-Esteem Scale” and “Beck Depression Inventory”. For data analysis, IBM SPSS 21 and IBM SPSS Amos 21 software were used. Results The calculated α for the AAQ-SA inventory was 0.80 and 0.81 for values commitment and defused acceptance dimensions respectively and 0.87 for the whole questionnaire. The correlation of the scale with the psychological flexibility, depression and Selfesteem was 0.44, 0.33 and -0.58, respectively; which represented the concurrent validity of the scale. Confirmatory factor analysis results also showed that two-factor model of Acceptance and action questionnaire – Substance abuse has good fitting the Iran’ community. Conclusion Psychometric characteristics of Acceptance and action questionnaire – Substance abuse showed that the questionnaire seems to be acceptable in Iranian society. It is a useful tool for research in the Addiction Treatment Centers. Keywords Experiential Avoidance, Psychological Inflexibility, Acceptance and Action Questionnaire – Substance Abuse, Validation Facilitating and Hindering Factors of Resiliency Against Substance Abuse in Adolescents and Young Adults Salah Adin Karimi1, Farahnaz Mohamadi2, Mariam Sharifian Sani3, Hasan Rafiee4, Zahra Jorjoran Shushtari5 1. PhD Student of Health and Social Welfare, University of Social Welfare & Rehabilitation Sciences, Tehran, Iran 2. PhD Nursing, Associate Professor University of Social Welfare & Rehabilitation Sciences, Tehran, Iran 3. PhD Social Policy, Assistant Professor University of Social Welfare & Rehabilitation Sciences, Tehran, Iran 4. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 5. PhD Student of Social Determinants of Health, Social Determinants of Health Research Center, University of Social Welfare & Rehabilitation Sciences, Tehran, Iran Background and Aim Substance abuse is a major public health problem in many societies. Resiliency can play key role in substance abuse prevention. The aim of this study was to explore the facilitating and hindering factors of resiliency against substance abuse among adolescents and young adults in Tehran Methods This qualitative study was conducted by using the basis theory method based on Strauss and Corbin’s approach. The purposeful sampling was used to select participants who grow up in high risk neighborhood of Darvazeh Ghar in Tehran. Data was collected through open unstructured interviews and focus group discussion in 2011. Fourteen interviews and one focused group discussion were held with 12 and 7 participants, respectively. Lincoln and Goba(1985) criteria was used for evaluating trustworthiness the findings S58 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Results Obtained codes consists of individual characteristics, family support, culture, spirituality, spiritual beliefs, living environment and social interventions from organizations based on the nature were as facilitator or hinder the resiliency process of drug abuse. Each factor based on features of sub categories were classified in three main categories of micro, mid and macro Conclusion Based on the findings from the participants’ experiences , fostering facilitator factors as creating and reinforcing the supportive environments, including Supervision and promote awareness through education of parents and family, improve interpersonal relationships in the environment, reinforcing spirituality and spiritual beliefs and social interventions can improve the individual resiliency against drug abuse. Reducing risk factors and fostering resiliency are part of a comprehensive approach to prevention, and are consistent with a public health approach. Keywords Conclusion Growing evidence suggests the role of epigenetic mechanisms on the behavior of drug abuse. Epigenetic targets may be the attractive targets for prevention and the treatment of drug addiction. Keywords Drug Addiction, Epigenetics, MiRNA, Methylation, Histone The Effect on Pregnancy Outcome of Drug (Substance) Abuse During Pregnancy. Maryam Kashanian 1, Hourieh Hatami2 1. Iran University of Medical Sciences 2. Iran University of Medical Sciences Background and Aim Substance Abuse, Resiliency, Qualitative Research, Iran The Epigenetic Mechanisms in Addiction: Basic Concepts and Future Perspective Morteza Karimipoor1 1.Molecular Medicine Department, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran. Background and Aim Epigenetics is the heritable and possibly reversible modifications in gene expression that do not involve alterations in the DNA sequence. DNA methylation, histone modifications and noncoding RNAs are main mechanisms of epigenetic alteration that influence the expression of genes. The understanding of the epigenetic mechanisms involved in addiction may lead us to prevent or reverse this status. The aim of this presentation is looking at the epigenetic mechanisms involving in drug addiction that has been studied in recent years. Methods The expression of genes in reward regions of brain may contribute in the pathogenesis and persistence of addiction. Recent studies have focused on the alteration of transcription factors, histon modification, DNA methylation and microRNAs on the regulation of gene expression that contribute to the addiction to psycho stimulant drugs. Results aspect of addiction. The level of expression of miR-212, miR-124 and miR-9 and therefore, the deregulation of their target genes make complex networks. The alteration in the expression of some transcription factors like deltaFOSB, CREB, NF-kappaB, and MEF2 genes in key brain reward regions like nucleus accumbens and prefrontal cortex. some drugs change the acetylation and methylation of histon residues in the brain through the altered expression of histone acetylase enzyme.Also, some studies indicate the effect of the cocaine administration on the level of expression of Mecp2 DNMT genes. These genes have key role in methylation of DNA. Increasing attention has been made on the role of microRNAs in different Substance abuse during pregnancy is one of the most important problems in maternal and neonatal health. Being familiar with the risk of poor pregnancy outcome in these individuals may help them to reduce that risk. The purpose of the present study is to evaluate the effects on Pregnancy outcome of substance abuse during pregnancy. Methods The study was conducted as a historical cohort study between two groups of pregnant women with or without substance abuse. Both groups were Iranian housewives, with the same socio economical status, singleton and without any known medical systemic disorder. Results 1268 women were evaluated in total. 317 women were drug abusers and 951 women were not. The woman in both groups had no significant differences according to neonates’ gender, gestational age, pregnancy-induced hypertension, intra uterine fetal death (IUFD), and ruptured membranes. Maternal age (P=0.000), maternal weight (P=0.000), neonatal weight (P=0.000) were found to be lower in drug abusers. History of previous abortion (p=0.000) and gravidity (P=0.000) were higher in drug abusers. Also cesarean delivery [(P=0.049, RR=1.1 (1.02-1.12)], placental abruption [(P=0.000, RR=2.7 (1.8-4.1)], meconium passage [P=0.000, RR=2.6 (2.3-2.8)], neonatal weight of less than 2500 gram [P=0.000, RR=1.9 (1.8-2)], Apgar score of less than 7 in minute 5 [P=0. 001, RR= 1.7 (1.5-1.7)], NICU admission [P=0.000, RR= 3.7 (3.5-3.8)] and neonatal death [P=0.009, RR= 2.1 (1.8-2.5)] were all higher in drug abusers. Conclusion Substance abuse causes poor outcomes in pregnancy, and with control, patients may improve these poor conditions. Keywords Substance Abuse, Drug Abuse, Pregnancy, Pregnancy Outcomes, Low Birth Weight, Birth Weight, Apgar Score, NICU, Pregnancy Induced Hypertension (PIH), Placental Abruption. Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S59 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Reconsolidation Memory and Addiction Fatemeh Kermanian1 1. Assistant Professor, Department of Anatomy, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran Background and Aim The formation, storage and use of memories is critical for normal adaptive functioning, including the execution of goal-directed behavior, thinking, problem solving and decision-making, and is at the center of a variety of cognitive, addictive, mood, anxiety, and developmental disorders. Drug addiction is one such disorder; it is both chronic and relapsing, and one prominent risk factor for a relapse episode is the presentation of environmental cues that have previously been associated with drugs of abuse. Methods Addiction is a complex disorder, and one characterised by the acquisition of maladaptive instrumental (drug-seeking and drugtaking) and pavlovian (cue-drug associations) memories. A leading hypothesis guiding current molecular and cellular research into drug addiction conceptualizes key aspects of addiction as a form of memory in which common neuroplasticity mechanisms that mediate normal learning and memory processes are ‘stealed’ by exposure to drugs of abuse to produce pathologic addictionrelated memories. Results These memories markedly contribute to the long-term risk of relapse, so reduction of the impact of these memories on behaviour could potentially be an important addition to current therapies for addiction. Memory reconsolidation may provide such a target for disrupting well-consolidated pavlovian cue-drug memories following an extensive drug history. Conclusion The disruption of drug memory reconsolidation could potentially provide a form of pro-abstinence, anti-relapse treatment for drug addiction. Keywords Memory, Addiction, Learning Effectiveness of Mindfulness Based Stress Reduction on Reduce drug-Taking and Drug Abuse Tempting Ideas in College Students Masoud Khakpour1, Masoomeh Mehrafarid2 1. Imamreza International University, Mashhad, Iran 2. Cuonselor in Minstry of Educaton, Iran. Background and Aim Today, drug abuse because false beliefs in the population are growing. This study examined the effectiveness of Mindfulness Based Stress Reduction on Reduce drug-taking and drug abuse tempting ideas in college students. Methods In a semi-experimental study, 39 subjects with diagnosis of high scores in drug-taking and drug abuse tempting ideas questionnaires were divided into two experimental group (19 subjects) and control group (20 subjects). The experimental groups received 10 sessions of Mindfulness Based Stress Reduction and the control groups did not receive any treatment. All subjects were assessed by drug-taking and drug abuse tempting ideas questionnaires in pre-test, post-test and after a 3-month follow up stages. Data were analyzed using covariance analysis. Results Covariance analysis showed a significant difference between experimental and control groups in drug-taking and drug abuse tempting ideas in college students in post-test and follow-up phases. Conclusion According to the findings Mindfulness Based Stress Reduction is effective in decreasing drug-taking and drug abuse tempting ideas in college students. Keywords Mindfulness, Stress Reduction, drug-taking, drug abuse tempting ideas, students The Effect of Psychodrama on Change of Control Location and Addiction Relapse in Cured Addicts at Isfahan Social Welfare and Rehabilitation Center Hossein Khakshoor1, om Albanin Esmatpanah2 1. M.A psychology,Behzisti Organization of Esfehan,Iran 2. M.A Student Positive Psychology Oriented, Azad University of Naeen, Esfehan, Iran Background and Aim Introduction : Since everyday 500 of country’s youngsters are getting addicted , researches have shown that the number of addicts in Iran is doubled each 10 years . Start age of addiction has reached averagely under 15 and national detriments of addiction reach more than 15 thousands Billions Rails per year all over the country. high percentage of who can stop addiction will be relapsed again and will make more irrecoverable detriments to society’s facilities .thus needs for performing of continuous scientific research for recognizing cause and results of addiction and also methods to preventing its relapse is obvious . for that reason in this research the issue of psychodrama is used and executed as a lever to fight addiction and prevention of its relapse. Methods This research is an experimental research of pretest and post-test type with control group which is done in ESFAHAN city with the aim of determining effect of psychodrama on changing control position and relapse to addiction in cured addicts . four hypothesis supposed for it and 60 cured male addicts were selected by random sampling to test them and then were put in each pairs of control and test group . both groups were pre-tested by questionnaire , Internal –External control questionnaire of RATER and S60 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall relapse to addiction scale and then test group particlpated in 16 psychodrama session for 3 months in 16 stages but no variable exerted to control group. both groups were finally post-tested by Internal –External control questionnaire of RATER and relapse to addiction scale. Data was analyzed by co-variance analytic statistical method and SPSS software (version 11/5). Results Statistical analytical results showed that psychodrama is operational on changing control position and relapse to addiction ( p < ./..1). it means psychodrama caused that control position of cured addicts be more internalized and due to this method relapse to addiction decreased in individuals . Conclusion It that mentioned psychodrama is operational in changing control position and relapse to addiction . considering experimental and theoretical history indicate that psychodrama have had prominent role in different countries because of profundity and variety and its operational view to different aspect of human life in various prevention like prevention of cigarette , alcoholic drinks , narcotics , aggressive behavior and other cases . it is because of this method’s universality and its practical and operational method of execution . Keywords Psychodrama, Changing of Control Position , Relapse to Addiction , Prevention and Addiction . Validation of the Amphetamine Cessation Symptom Assessment Questionnaire for Evaluation of Methamphetamine Wthdrawal Symptoms Yousef Khani1, Saharnaz Nedjat2, Hossein Mirzaei3, Alireza Khanzade4, Shahnaz Rimaz5 1. Department of Epidemiology & Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran 2. Department of Epidemiology & Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran 3. Department of Epidemiology & Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran 4. Residential Treatment Center for Homeless Addicts in Alborz Province, Karaj, Iran 5. Department of Epidemiology, School of Public Health, Iran University of Medical Sciences, Tehran, Iran Background and Aim The used of psychiatric substances and drugs has became the major problem in today world. In recent years, the problem of abuse and dependence to synthetic substances, especially Methamphetamine (crystal), in Iran has become the serious and emergency hygienic problem. According to importance of the existence of appropriate tools in order to Methamphetamine withdrawal symptoms assay and Amphetamine Cessation Symptom Assessment questionnaire( ACSA) designers’ suggestion that later researches should survey the application and use of this questionnaire in withdrawal symptoms assay in the consumption groups from psychotropic’s such as Methamphetamine and Lack of generalization of studies and foreign questionnaires inside of the country, the present study was done for validation of ACSA questionnaire in patients in homeless addicts’ residential treatment center of Alborz province. Methods ACSA was translated from English to Persian by back translation and was analyzed its appearance and content validity in group discussion sessions among professionals and addicts who had attempted to quit it recently. Content validity index (CVI) was used for content validity evaluation. Among people that had been accepted for methamphetamine withdrawal in homeless addict’s residential treatment center in alborz province, 106 people were selected by available sampling method and completed the questionnaire. Cronbach’s alpha was used for internal consistency assessment of the questionnaire and in order to structural validity analysis of the questionnaire, was used the principal components analysis (PCA), Scree test (Scree Plot) and orthogonal rotation method. Results Appearance and content validity of questionnaire were analyzed in the group discussion sessions among professionals and addicts who had attempted to quit and finally, slight variations was applied in questions structure. CVI index was 87.5% for total of the questionnaire. Determination of structure validity by principal components analysis (PCA) showed that this questionnaire has been composed of three main factors contain of anxiety and mood, tiredness and Craving. The Cronbach’s alpha value was calculated for the total questionnaire (84%) and for the first factor (91%), the second factor (77%) and the third factor (96%). Conclusion This study showed the ACSA questionnaire has sufficient reliability and validity for the assessment of methamphetamine withdrawal symptoms and is useful tool for evaluation of Methamphetamine withdrawal symptoms in people who have quit it recently. Keywords Amphetamine, Methamphetamine, Crystal, Withdrawal, Validity, Reliability, Factor Analysis, Questionnaire The Impact of Assertiveness and Refusal Skills Training on Reduce of Relapse in Drug Addicts Bahman Bahmani1, Abdollah Hashemi2, Ozra Jahed Motlagh3, Mohammad Saeed Khanjani4 1. 3. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 2. Tabatabai University 3. University of Social Welfare and Rehabilitation Sciences, Department of Rehabilitation Counseling 4. University of Social Welfare and Rehabilitation Sciences, Department of Rehabilitation Counseling Background and Aim Relapse in addicts brings Many problems. The person who returns to drug use after a period of treatment, Involve to Hopelessness, guilt and loss of self-confidence. Objective: The Purpose of this study was to determine the effectiveness of assertiveness and refusal skills on reduce of relapse in drug addicts. Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S61 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Methods statistical population included drug addicts referred to opiate withdrawal centers in the Eghlid city that used opium, 30 people of them were selected purposively as research sample and randomly divided into experimental and control groups. Initially, both groups complete questionnaire of assertiveness Gambril and Richey. The morphine test also was performed on both groups, Then assertiveness and refusal skills were educated to experimental groups during 9 sessions . After completion of training, post-test was performed for both groups with assertiveness questionnaire and morphine re- test. For statistical analysis , obtained data were analyzed with covariance and chi-square test and using SPSS. Results Findings: Significant difference found statistically between experimental and control groups, in mean scores of assertiveness after training (p˃0/05، F= 4/91، df= 1). Variable size effect in experimental group was 0/15. In other words, the independent variable is able to explain 15 percent of assertiveness variance. In post test , from 15 participants in the experimental group, 66/86 percent were healthy and 33/13 percent were addicted, but In the control group, These percentages were respectively 33/53 and 66/46 for healthy and addicted people. According to the results of the chisquare test to determine differences in observed frequencies, Chisquare amount (97/3) showed significant difference in the level of 0/05 between two groups. Conclusion This study, using analysis of covariance and chi-square test indicated that the refusal and assertiveness training program significantly reduced the relapse in experimental group than control group. Therefore, assertiveness and refusal skills training can be used as a useful intervention for the prevention of relapse in addicts. Keywords Addiction, Relapse, Assertiveness and Refusal The Relationship between Spiritual Intelligence and Self-Efficacy with the Tendency Towards Addiction among High School Female Students in Hamadan Nahid Kharaghani1, Leila Dehnavi2 1. MA in Counseling and Guidance, Islamic Azad University, Sciences Kermanshah Research, Iran, nkharaghani.68@gmail.com 2. MA in Counseling and Guidance, Islamic Azad University, Sciences Kermanshah Research, Iran, leilad6358@gmail.com Background and Aim Substance abuse is one of the major health and social problems of modern society, especially in developing countries. Students can take a variety of reasons, including frustration, adventure, pleasure-seeking, variety seeking may be at risk of substance use. Since the starting age of drug use is on the decline, and focus on students, according to their readiness for this class for drugs and to identify variables associated with it will be important. Self belief is a significant factor in human merit system manufacturer. belief implies that the Self-efficacy of thoughts, beliefs and feelings that influence individual behavior and spiritual intelligence also refer to The ultimate degree of intelligence a person who assists him in understanding and doing the right things. Self-efficacy is one of the variables that is associated with substance abuse, including individual judgments about the capability, capacity and its ability to perform specific tasks. An other psychological factors associated with drug abuse, is sensation seeking. Sensation seeking,is defined as thrill seeking , diverse, fresh, sophisticated and also willingness to take risks. The purpose of this study is to investigate the relationship between intellectual intelligence and selfefficacy with the tendency towards addiction in female students in secondary schools Hamedan. Methods The population study of secondary school students in Hamadan comprise academic year 92-93. The present research sample of 210 public school students who were randomly selected. For collecting data the student, self-efficacy scale , sensation seeking scale and their potential for drug abuse, was used Results The results of this study showed that there is a negative relationship between self- efficacy and potential drug abuse among students. Another part of the results showed that there is a positive relationship between sensation seeking and talent drug abuse. Conclusion The results of this study showed that there is a negative relationship between self- efficacy and potential drug abuse among students. In other words, with increased efficacy, the drug tends is reduced. Another part of the results showed that there is a positive relationship between sensation seeking and talent drug abuse. In other words, with increased sensation seeking, susceptibility to drug abuse among students increases. Thrill-seeking behaviors of persons with drug abuse tend to be higher than in normal people. Keywords Spiritual Intelligence, Self-Efficacy, Addiction Adaptation of School-Based Interventions Guideline to Prevent Smoking Fariba Khayyati1, Fatemeh Sadeghi-Ghyassi2, Sakineh Hajebrahimi3, Hamid Allahverdipour4 1. Tabriz Health Services Management Research Center 2. Iranian Evidence Based Medicine Center of Excellence, Tabriz University of Medical Sciences, Tabriz, Iran 3. Iranian Evidence Based Medicine Center of Excellence, Tabriz University of Medical Sciences, Tabriz, Iran 4. PhD Professor, Tabriz University of Medical Sciences, Department of Health Education & Promotion School of Health, Tabriz, 14711,Iran Background and Aim Tobacco use has a serious impact on health and socio economics situation of general population. Majority of people has started it in teen age and the most of them will probably be addicted. Meanwhile, school-based interventions can play an essential role in prevention or delay tobacco consumption, but there is no structured program for such interventions in Iran. Current study has S62 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall been designed to provide a national evidence based guideline for school- based interventions. Methods We conducted wide search main databases and websites considering Pub Med, NICE, GIN, NGC, SIGN and other related websites for defined keywords. Related guidelines were selected and appraised by two independent experts using AGREE-2 tool. The highest record was translated to Persian and discussed in panel of guideline for adopting with Iranian culture and condition. The preview was sent to experts and stockholders for final edition and then was published for pilot application. The results of analysis of Covariance showed that the means of scores of the training group were significantly reduced as compared to the control group on aggression both in the post test and follow-up. Conclusion Based on the results of this study can be concluded that effective problem solving training on the aggression on drug dependent patients. Keywords Problem Solving-Aggression Results Eleven related guidelines retrieved in which only two were about school-based interventions recommended. The main recommendations for prevention of smoking was as following: Pay attention and take the organizational wide approaches in schools, plan and do interventions by adults, plan and do interventions by peers, train, retrain and develop, and Pay attention and take the coordinated approach. Conclusion Iranian school based guideline is a well adopted tool to prevent tobacco consumption in teen ages. Keywords Guideline, Prevention, School-based Intervention, Smoking Effectiveness of Problem-solving training Intervention on the Aggression of Drug- Dependent Patients in Shiraz Sadrollah Khosravi , Sadrollah Khosravi , Masoumeh Hamidi(MAs) , Eshaq Ebrahimi(MA)4, Tayebeh Shahrivar5, Ali Reza Rahimi6 1. -Assistant Professor,Dep. of Psychology ,FiroozAbad Branch,Islamic Azad University,FiroozAbad,Iran 2. Assistant Professor,Department of Psychology ,FiroozAbad Branch,Islamic Azad University,FiroozAbad,Iran. 3. -Dep. of Psychology ,College of Humanity Science,Yasouj,Sciense and Research Branch ,Islamic Azad University,Yasouj,Iran. 4. Assistance Correcting and training of Fars Prisons Organization,Shiraz,Iran. 5. -Dep. Of Psychology,Fars Science and Research Branch, Islamic Azad University Marvdasht,Iran. 6. Dep. Of Psychology,Fars Science and Research Branch, Islamic Azad University Marvdasht,Iran. 1 2 3 Relation of Variables Related to Substance Abuse with Tendency to Addiction Treatment in Self Reported Addicts Hamidreza Khosravi Zade Tabasi1, Farah Madarshahian2, Javad Sohaili3, Mostafa Abdollahi4 1. Birjand University of Medical Sciences 2. Birjand University of Medical Sciences 3. Tabas Treatment Health Center 4. Khomeini Hospital of Tabas Background and Aim Addiction and drug abuse is one of the four crises in the world and Iran is one of high risk countries. For prevention and treatment of addiction, knowing variables relate to addiction has special importance. This research is conducted to determine Relation of Variables related to substance abuse with tendency to addiction treatment in self reported addicts. Methods In this descriptive analytic study 195 self reported substance addicts referring to center for addiction treatments of Tabas city were studied through census sampling. Instrument for gathering data was a structured interview form with two parts: 1- demographic data and 2- data about their addiction status and tendency to addiction treatment. Responds were categorized in two categories: agree and disagree for some questions and yes or no in other questions. Data was analyzed using descriptive and inferential (chi square, logistic regression) statistics by SPSS software. Results Background and Aim The purpose of this study was to determine the effect of problem solving on aggression in addicted subjects. Methods Results Therefor addicted subjects were randomly selected and assigned to the training and control groups. The Aggression Questionnaire were administered as the pre-post& follow-up tests. After the pre test the training group received 8 sessions(90 minutes each) of problem solving training. The follow-up test was administered one month after the end of training. Finding showed 90.3% of participants were male and 9.7% were female. The mean age of participants was 35.3 ± 1.17. 72.8% were married. 42.9% were worker. The most addiction treatment causes were 36.9% tiredness of substance abuse and 17.4% expense of drug and substances and 11.3% both of them. There was significant difference between physical symptoms and tendency to addiction treatment (P=0.05) and also tendency to addiction treatment and family problems (P= 0.04). There was significant difference between vanity and history of being in prison (P= 0.03). A significant difference was noted between tendency to addiction treatment and worthlessness (P=0.025) and also despair (P=0.05). Living with family can increase 1.8 times (P=0.05) and decision for marriage increase 2.3 times (P=0.03) chance of tendency to addiction treatment. Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S63 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Conclusion Tendency to addiction treatment may increase with positive family factors and expense of drug and substance. Keywords Substance Abuse, Treatment Addiction, Self-Reported Addicts Relationship between Personality Characteristic and Defense Mechanisms with Addiction Preparation in Students Mahnaz Khosrojavid1, Robabeh Delazar2, Maria Firoozshad3, Razieh Hedayatsafa4 1. Psychology Department, University of Guilan, Rasht, Iran 2. Psychology Department, University of Guilan, Rasht, Iran 3. Organization of Traning and Education, Rasht, Iran 4. Organization of Traning and Education, Rasht, Iran Background and Aim Addiction Preparation is talent addiction. The people who have high drug preparation, are more susceptible to addiction. The present study aimed to examine relationship between personality characteristic and defense mechanisms with addiction preparation in students. Methods The study design was description and cross-sectional. For the present study, all students in the Faculty of Letters and Human Sciences, University of Guilan (4500 thousand people, ages 36/20) who were enrolled in the first semester 93-92 formed. Of these, 285 patients were randomly selected. NEO-FFI-R, the Defense Mechanisms and Addiction Preparation Questionnaires were the research tools. The gathered data were analyzed through correlation, regression and multifactorial variance. Results Pearson correlation test showed a significant negative correlation addiction preparation with 4 dimension of the personality characteristics and positively correlated with the personality trait neuroticism respectively. Significant positive correlation with active addiction preparation defensive style immaturity. Addiction preparation passive defensive style immaturity significant positive correlation with the 01/0 and a negative correlation with defensive style developed in 05/0 showed. Regression analysis for the five personality dimensions the variance addiction preparation Active / Passive (criterion variables) show that, respectively, about 32 and 22 percent of the variance in the criterion variables already be predictor is projected. The results of the regression analysis of personality characteristics (predictor variables) on mature and immature defense styles of variance (criterion variables) indicate that about 25 and 17 percent of the variance in pre -criterion by changing the nose foreseeable. Results of multivariate analysis of variance showed that the mean scores of boys grown and immature defense style, significantly higher scores than female students. Conclusion Given the high prevalence and negative consequences of widespread abuse in youth, it seems that preventive measures are necessary. Given this context, the role of internal features for efficient design and implementation of programs that would be helpful. Keywords Personality Characteristic, Defiance Mechanisms, Addiction Preparation, Students. Mediation of Personality Influences on Alcohol Consumption within the Theory of Planned Behavior in Adolescents on Zanjan 2014 Qamar kiani1, Narges Rasoli2 1. Psychologist in Zanjan University of medical sciences, Zanjan, Iran 2. Kashmar Branch ,Islamic Azad University Background and Aim This study aimed to explore the role of mediator structures the theory of planned behavior in relationship between alcohol consumption and personality. Methods In a cross - sectional study, were selected 390 students (195 girls, 195 boys) high school on Zanjan with mean and standard deviation of age (M= 16.4, SD=1.48) with multi- cluster sampling method. Data were collected using the short form of Big Five personality Inventory and questionnaire designed based on the theory of planned behavior Ajzen about the behavior of alcohol consumption and was analyzed with Lisrel 9.5 in causal model frame, using path analysis. Results Agreeableness and extraversion had significant correlation between alcohol consumption (p<0.01). Model had goodness of fit. Direct effect of Agreeableness and extraversion on alcohol consumption was Respectively (β=.37 , p<0.01) (β= .12 , p<0.05). Descriptive subjective norm, perceived behavioral control and intention were mediated relation Agreeableness and alcohol consumption . perceived behavioral control and intention were mediated relation extraversion and alcohol consumption , perceived behavioral control had more total effect in both. Conclusion Considering resistance of personality to change , prevention program based on TPB for alcohol consumption could be effective. Keywords Personality, Theory of Planned Behavior, Alcohol Consumption, Adolescence Comparison the Executive Functions of Inhibition and Problem Solving in Adolescents with and Without Substance Abuse Tahereh Maasoomi Mofrad1, Hamid Alhzadeh2, Ahmad Khamsan3 1. khorasan Jonuby-Shahrstan Berjand-Khyahan Toohed-Toohed2-Plak6 2. khorasan Jonuby-Shahrstan Berjand-Khyahan Toohed-Toohed2-Plak6 3. khorasan Jonuby-Shahrstan Berjand-Khyahan Toohed-Toohed2-Plak6 S64 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Background and Aim Executive functions are self-regulated functions and show the ability to inhibition, self-changing, planning, organization, using the working memory, solving problems and targeting for homework and school activities. This study compares the executive functions of inhibition and problem solving in adolescents with and without substance abuse Methods Causal-Comparative Results 15 adolescents with substance abuse and 15 normal adolescents were selected which matched each other with the same age, sex and education. The research tools were Wisconsin Card, was used for assessing the inhibition executive functions, and Heppner and Petersen Questionnaires for problem solving Conclusion The results showed that there were statistically significant differences between groups between average score of inhibition executive functions and solving problem (except trend– avoid component). There were not statistically significant differences in the average score of inhibition executive functions and solving problem according to age, sex and education. It is concluded that the drug addicts are weaker than those without substance abuse based on the inhibition executive function and problem solving. These findings can be used for the prevention program Keywords Executive Function, Inhibition, Problem Solving, Substance Abuse Relation of Social Supports with Prevention of Re-addiction According to Treated Addicts View Points Farah Madarshahian1, Mohsen Hassanabadi2, Elnaz Kheirandish3 1. Birjand University of Medical Science 2. Birjand University of Medical Science 3. Mashad Azad University Background and Aim Social support is one of the most powerful and effective factors for successful managing stressful conditions. Social support simplifies difficulties for the patients. According to reports only 20% to 30% of treated addicts do not have recurrence so, this study conducted to determine Relation of social supports with prevention of re- addiction according to treated addicts view points. Methods In this descriptive analytic study 50 treated addicts who refer to Birjand medical and hygiene centers were selected through census sampling. Instrument for gathering data was a questionnaire with two parts: 1- demographic data and 2- data about social supports with 15 questions such as availability of job, insurance treatment, settlement, retrieve their children from family or Behzisti center, availability center for professional education. Responds were categorized in two categories: agree and disagree. Data was analyzed using descriptive and inferential (student T test, chi square, logistic regression) statistics by SPSS software. Results Results showed 72% of participants were male and 38% were female. The mean age of men was 41.2 ± 3.6 and women 39.3 ± 3.6. 80% of men and 86% of women were married. Participants believed that absence of job and enough income 6.2 times increase the odds ratio of re-addiction (P=0.03). There was no significant difference between view points of men and women in this question. Absence of settlement 5.3 times increase the odds ratio of re-addiction (P=0.025). There was significant difference between view points of participants according to marriage status in this question (P=0.05). The odds ratios of re-addiction increase 4.4 times with absence of insurance and 2.3 times with do not retrieve their children. There was significant difference between view points of men and women in these questions. Periodic follow up can decrease 5.4 times odds ratio of re-addiction and there was no significant difference between view points of men and women (P=0.18). Conclusion Social support of treated addicts can decrease odds ratio of readdiction and Periodic follow up can be helpful for early identifying re- addiction factors. Keywords Re- Addiction, Social Support, View Point Deep Analysis of Biopsychosocial Risk Factors of Addiction According to View Points of Addict Women Farah Madarshahian1, Mohsen Hassanabadi2, Elnaz Kheirandish3 1. Birjand University of Medical Science 2. Birjand University of Medical Science 3. Mashad Azad University Background and Aim Addict women are more vulnerable than men because, substance abuse is accompany by social hurts such as escape from home, violence, prostitute and… . One of the most important goals of WHO in 21 century is involving women in development of industry and social systems. One of the ways for access to this goal is women empowerment and abates their problems. This study conducted to determine analysis of biopsychosocial risk factors of addiction according to view points of addict women. Methods In this descriptive analytic study 70 addict women who referred to Birjand medical and hygiene centers were selected through census sampling. Instrument for gathering data was a multiaspect interview form that its questions designed according to researches and text books. This form consist of three parts: 1- demographic data and questions about biopsychosocial, religious, recreations, economic, and addiction conditions 2- questions about their spouse and children condition of physical, psychic, religious, social, economic status 3-questions about their family and sibling Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S65 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall condition of physical, psychic, religious, social, economic status. Data was analyzed by descriptive and inferential (student T test, chi square, logistic regression) statistics. Results Finding showed that the most frequency distribution of participants 44% were in the range of 26-35 years, 50% of them were illiterate, 40% married, 16% divorce and 14% widow. The reason of addiction according to their view points 41% were physical problems, 59.2% relief pain, 26% problems in the life. The odds ratios of addiction increase 6.2 times with somatic pain (P=0.02). Finding about their children showed that 70% of them have children, 5% of them had children which born in prison, 10% had ill children, at least one of their children died in 49% of cases. According to their view points, risk of addiction was increased 8.7 times with child mortality (P=0.01). Data about their family showed 56% of their father or mother or both died. Missing of Parents increased odds ratio of addiction 4.5 times (P=0.04). There was significant difference between the age of missing parents and addiction (P=0.04). 56% of them had not any plan for their future and there was significant difference between absence of planning for future and treatment of addiction (P=0.03). Conclusion Deep analysis of women problems and identifying them can be helpful for preventive planning of addiction. Keywords Biopsychosocial, Addiction, Women, Risk Factor Alcohol Addiction Recovery and Nutrition Deficiency Zahra Maghsoudi1 1. Nutrition Department, Dr. Shariaty hospital, Health Care System of Social Security Organization of Isfahan, Isfahan, Iran Background and Aim Addiction and drug dependence have multifactorial effects on various organs and body cell metabolism. Psychological aspects of addiction dependence accompany with malnutrition and food sensitivities. This study tries to focus on nutritional deficiencies which are accompanied with alcohol addiction and it should be modified in recovery periods. Methods Several databases including ISI (web of sciences), Scopus, PubMed, Science Direct, Iran Medex, and MagIran were searched for following key words such as “nutrition”, “alcohol addiction”, “neurotransmitters”, “addiction recovery”, “diet”, “food”, “alcohol” and “nutrients” up to 2014. The search strategy was without any language or time period restriction. All of the references and citation of related-articles had been scanned, too. Results Abused Substances especially alcohol addiction can play effective roles on neurotransmitters balance and their function including gamma-aminobutyric acid (GABA), serotonin, endorphins and enkephalins. This can be associated with occurrence of hypoglycemia and diabetes mellitus, depleting major minerals including calcium and leading to lowering bone mineral density and osteoporosis. In addition, increasing intake of immune and gastrointestinal function effective nutrients as glutamine amino acid, and food sources rich of magnesium, calcium, vitamin D and Omega 3 fatty acids can be effective in solving its related health problem Conclusion Disrupting neurotransmitters which effect on healthy function of brain and improving physical and emotional damage can be managed by increasing intake of mineral rich foods such as dairy, cheese, soya milk, beef, walnut, flax seed, fatty fishes, vegetables and fruits. Keywords Alcohol, Addiction Recovery, Nutrition Deficiency The effect of nutrition on addiction recovery Zahra Maghsoudi1 1. Nutrition Department, Dr. Shariaty hospital, Health Care System of Social Security Organization of Isfahan, Isfahan, Iran Background and Aim Brain is receiving all the nourishment it needs through food brain neurons can function properly and naturally maintain a proper balance of neurotransmitters which are produced by assembling them from the nutrients in the food you eat and their Imbalances can alter mood and behavior. Addictive substances can disrupt this balance in the brain, Diet can influence the mentioned balance. This study focused on nutritional deficiencies and addiction recovery in these individuals. Methods Scientific databases such as ISI (web of sciences), Scopus, PubMed, Science Direct, Iran Medex, and MagIran was searched for main key words such as “nutrition”, “addiction”, “neurotransmitters”, “addiction recovery”, “diet”, “food” and “nutrients” up to 2013. Our search strategy was without any language or time duration restriction. References and citation of related- articles had been searched, too. Results Our finding reflected that addiction recovery should be associated with consuming a high protein diet and consuming meals that consists of protein-rich foods containing tryptophan and serotonin at meals at regular intervals to regulate the production of neurotransmitters seeds, almonds, hazelnuts sesame seeds, pumpkin, sunflower, beef, shrimp, chicken, soya, milk and banana can play effective roles in keeping neurotransmitters balance. Conclusion Addiction recovery with consuming a diet that consists of rich protein foods at regular meal intervals can regulate brain neurotransmitters production and keep the individuals free from cravings S66 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Keywords Conclusion Nutrition, Addiction recovery, Diet The Necessity of Using Standardized Nursing Cares in Neonatal Born from Mothers with Substance Abuse Zahra Mahdavi1, Abbas Abbasszadeh2, Maryam Rasouli3, Farid Zayeri4 1. Shahid Beheshti Medical University 2. Shahid Beheshti Medical University 3. Shahid Beheshti Medical University 4. Shahid Beheshti Medical University Background and Aim Substance abuse in pregnant women is one of public health problems in most countries. Currently, the rate of substance abuse in pregnant women is 11percent which is more than the rate in the past and has led to various problems in mother, fetus, and newborn. Substance abuse during pregnancy has many effects on the mother and newborn. Premature delivery, abortion, placental abruption, and postpartum hemorrhage are some effects of substance abuse in women, increased risk of health problems such as malnutrition, anemia and multiple infectious complications of substance abuse in women. On the other hand, intrauterine growth restriction, premature birth and stillbirth, low Apgar score, meconium aspiration, microcephaly, low birth weight and neonatal withdrawal are the effects of these substances on the health of newborns. Neonatal Abstinence Syndrome(NAS) is a condition which is seen in more than half of newborns of these mothers few days after birth, and causes some symptoms in central nervous system(Tremor, irritability, seizures, insomnia and muscle stiffness) digestion system(diarrhea, vomiting, dehydration and difficulty in feeding) and respiratory(apnea, tachycardia, tachypnea). Awareness of nurses and caregivers about the signs and control of symptoms of NAS in the newborns is essential. Methods In this study, nursing care given to 400 newborns were evaluated and compared by the help of a check list arise from the latest medical literature about newborns. This check list contained two standards of nursing care: pharmacological treatment and non pharmacological treatment. Symptoms of NAS in the newborn must be scored with an effective tool. Newborns with minimum score require no medical intervention. Modified and reduced environmental stimulation, avoiding excessive light and noise, reduction of manipulation and calm control of the newborns can be effective in controlling these babies. Drug treatment of newborns with a high score and prone to seizures is necessary. Drugs, including morphine, diazepam and Phenobarbital, are selected according to clinical symptoms of newborns and drugs used by mothers. Nurses must provide these newborns with nursing care based on the latest global standards. Results Our findings indicate about 45 percent of newborns require receiving non-pharmacological treatment and 55 percent of newborns require receiving pharmacological treatment. Also this research identified that nursing care provided to these infants is about 77 percent of the standard mode. According to the performed research, it was also identified that the shortage of nurses’ awareness of evaluating babies with standard scoring table is a problem. Increasing nurses’ awareness about preterm identifying and controlling of these symptoms by standard neonatal care protocols will decrease early and late effects. Keywords Neonatal Substance Abuse, Mother’s Addiction, Auditing The Prediction of Work Addiction Based on Emotional Intelligence in Education Staff Mohsen Makhlough1, Zahra Simi2, Elham Izadi3 1. Department of General Psychology, Science and Research Branch, Islamic Azad University, Arak, Iran. 2. MA in Family Counseling. Allame Tabatabee, Tehran, Iran. 3. M.A in Family Counseling. Ghuchan Islamic Azad University, Iran. Background and Aim The purpose of this study was to investigate the predictive role of emotional intelligence in work addiction among education staff. Methods In this multivariate correlation, the subjects consisted of all education staff in Mamasani. The statistical sampling included 180 employees selected in classification random. In this study Spinzo Robins (1992) work addiction questionnaire and barberi and Grievz (2005) emotional intelligence were used. the data was collected through descriptive statistical methods and inferential regression and then analysed. Results The findings indicate that there is a meaningful relationship between emotional intelligence and work addiction. the more emotional intelligence the less the amount of work addiction is and vice versa. Also, there is a meaningful relationship between intelligence in addicted people and non-addicted once. In other words, emotional intelligence in addicted people is less in non- addictive people. Conclusion Subjects with low emotional intelligence are likely to indulge in work addiction and this couses negative result influencing psychological health and life quality. It is likely that training emotional intelligence prevents this problem. Keywords Work Addiction, Emotional Intelligence, Training The Effect of High Frequency Repetitive Transcranial Magnetic Stimulation (rTMS) in Decreases of Smoking Nastran Mansouriyeh1 1. PhD Student of Health Psychology., Young Researchers And Elite Club,Tabriz Branch, Islamic Azad University, Tabriz, Iran. Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S67 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Background and Aim The aim of this study was to examine the efficacy of the repetitive Trans cranial magnetic stimulation rTMS in reduce of smoking in methamphetamine users. Methods Eight methamphetamine users were included in single subject method with multiple baseline design, comparing 15 days of active versus sham stimulation and control group. Outcome measures were high frequency rTMS effects on 4 subjects in experimental over left and right stimulation DLPFC groups. We measured with Fagerstrom Question before and during stimulation periods. Results Right and left DLPFC stimulation didn’t reduce smoking. Conclusion High frequency rTMS maybe don’t useful for reduce of smoking in methamphetamine users. Keywords Repetitive Transcranial Magnetic Stimulation (rTMS); Dorsolateral Pre-Frontal Cortex; smoking. Patients’ Views on the Differences between the Methadone Syrups Produced by Exir and Daroupakhsh Pharmaceuticals: A Qualitative Study Omid Massah1, Ali Farhoudian2, Mandana Sadeghi3, Hamed Bahari4 1. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 2. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 3. Physician, Addiction Therapist & Researcher 4. Physician, Addiction Therapist & Researcher Background and Aim Methadone is the main drug used in maintenance therapy with agonist drugs in substance abusers, and it is chiefly used in syrup form. An important aspect of any successful treatment program is patient compliance. Hence, this study was designed to compare the methadone syrups produced by two different pharmaceutical companies from the perspectives of patients and other concerned individuals. Methods A qualitative study was conducted via content analysis. Through purposive sampling 26 substance abuse patients visiting three clinics applying maintenance therapy with agonist drugs were selected and interviewed through focus group discussions. The patients had been on maintenance therapy for the past 18 months and had used both Exir and Daroupakhsh methadone syrups. Other concerned individuals included those who were somehow involved in the process of treatment: clinic nurses (3), drug experts in the ‘Substance Abuse Office’ of medical universities’ ‘Food and Drug Administrations’ (2), opiate drugs stock-keeper (1), clinic physician-technicians (2), and, methadone retailers and brokers (2). The latter underwent in-depth semi-structured interviews. Upon analysis the data were classified, coded and thematically grouped. Results The extracted codes were classified into four main themes: 1. Physical characteristics: syrup color, odor, taste and consistency. There was a high consistency among patients and other concerned individuals opinions regarding the syrups’ physical characteristics, such that their positive and negative points were highly reliable. The most outstanding aspect of this theme was Exir’s unpleasant taste and odor, as opposed to that of Daroupakhsh. 2. Therapeutic effects: onset of effect, potency and duration of effect. In the second theme however, the opinions greatly varied. The patients’ judgments appeared to be influenced by their mental prejudices, and somewhat affected by the syrups’ physical characteristics. 3. Side-effects: generalized, sleep, gastrointestinal, cardiac, respiratory, dermatologic, sexual, nervous, muscular and psychological problems. The interviewees’ opinions of side-effects were very different too, and there was little consensus among them. Patients had usually experienced more than one side-effect at different times, and were less certain which syrup they had used. In longterm treatments side-effects usually appear after a long time, and the drug causing the side-effect cannot be specified when more than one drug is being used. 4. Opinions, feelings, thoughts and excitements following syrup change: apprehension of unfamiliarity, upset about change without prior notice, unpleasant feeling about constant changes, feeling disrespected, feeling deceived, feeling of being imposed. The overall consensus in the fourth domain was very high among the patients. They felt unpleasant about the drug change and particularly that it was done without prior notice. Almost all felt bad and dissatisfied with this aspect of the treatment. Conclusion In a nutshell, patients’ dissatisfaction of the physical characteristics and mode of changing Exir syrup was very prominent. The latter was also thought to have less potency and maintenance as opposed to its Daroupakhsh counterpart, though we feel this information is not very reliable, based on the overall data gathered. In addition to the low consensus on the drug’s side-effects, it is basically very difficult to attribute such effects to a specific pharmaceutical product when different products are used interchangeably. Keywords MeThadone Maintenance Treatment , Exir Methadone Syrup , Daroupakhsh Methadone Syrup , Treatment Compliance Effectiveness of Gross Model-Based Emotion Regulation Training on Anger Reduction in Drug-Dependent Individuals Omid Massah1, Yousef Aazami2, Faramarz Sohrabi3, Younes Doostian4, Hamed Choopan5 1. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 2. M.Sc. Student of Psychology, Allameh Tabataba’i University, Tehran, Iran 3. Ph.D. in Clinical Psychology, Associate Professor, Allameh Tabataba’i University, Tehran, Iran S68 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall 4. PhD. Student of Rehabilitation Counseling, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 5. M.Sc. Student of Rehabilitation Counseling, Allameh Tabataba’i University, Tehran, Iran Background and Aim Difficulty in regulating emotions is one of the problems drug abusers face, and teaching these individuals to express and manage their emotions can be effective in reducing their problems. The present study aimed to determine the effectiveness of the Gross model-based Emotion Regulation Training on anger reduction in drug-dependent individuals. Results Findings showed significant differences between the two groups after intervention. Conclusion Methods The present study had a quasi-experimental design wherein pretest-posttest evaluations were applied using a control group. The population under study included all addicts visiting Marivan’s addiction centers in 2012-13. Convenience sampling was used to select 30 substance-dependent individuals who were then randomly assigned to the experiment and control groups. The experiment group received its training in 8 two-hour long sessions. Data were analyzed using analysis of co-variance and paired t-test. Results There was significant reduction in anger symptoms of drug-dependent individuals after ERT (P<0/001). Moreover, the effectiveness of the training on anger was persistent in the follow-up period. Conclusion The Gross model-based emotion regulation training can reduce symptoms of anger in drug-dependent individuals. Based on the results of this study we may conclude that the Gross model-based Emotion Regulation Training can be applied alongside other therapies to rehabilitate drug abusers undergoing rehabilitation. Keywords According to the findings Marlatt’s cognitive behavioral model is effective in increasing self-efficacy in opiate-dependents. Keywords Cognitive-Behavioral Treatment , Marlatt’s Model , Self-Efficacy , Opiate-Dependency Comparison of Personality Traits Based on Temperament and Character Inventory (TCI) in Opiate and Stimulant Abusers Zahra Karami1, Alireza Pirkhaefi2, Aminollah Kowsarnia3, Omid Massah4, Ali Farhoudian5 1. M.Sc. of Rehabilitation Counseling, Allame Tabataba’ee University, Tehran, Iran 2. Ph.D. in Psychology, Assistant Professor of General Psychology Department, Garmsar Branch of Islamic Azad University, Garmsar, Iran 3. M.Sc. of Clinical Psychology, Najafabad Branch of Islamic Azad University, Najafabad, Iran 4. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 5. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran Background and Aim Emotion Regulation , Anger , Drugs Effectiveness of Marlatt’s Cognitive-Behavioral Model on Increasing Self-efficacy in Opiate-dependents Younes Doostian1, Ali Shafie’abadi2, Seyed Mohammad Kalantar Kooshe3, Omid Massah4 1. Ph.D. Student in Rehabilitation Counseling, University of Social Welfare & Rehabilitation Sciences, Tehran, Iran 2. Ph.D. in Counseling, Professor of Psychology & Educational Sciences Faculty, Allame Tabataba’ee University, Tehran, Iran 3. Ph.D. in Counseling, Assistant Professor of Psychology & Educational Sciences Faculty, Allame Tabataba’ee University, Tehran, Iran 4. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran The aim of this study was to compare personality traits based on the temperament and character inventory (TCI) in opiate and stimulant users of Yasuj. Methods In this descriptive –comparative study, 115 persons (91 opiate substance users and 24 stimulant substance users) were selected by simple and convenient sampling from persons who were admitted to substance abuse treatment centers (MMT centers), addiction treatment camps and self-help groups and Narcotics Anonymous (NA) of Yasuj. Subjects were controlled for age. The data collection tool was the ‘Temperament and Character Inventory’ (TCI). Data were analyzed by SPSS using Levene’s test, ANOVA and Pearson’s correlation coefficient. Results Background and Aim This study examined the effectiveness of Marlatt’s cognitive-behavioral model on increasing self-efficacy in opiate-dependents. Methods ics in Khorramabad were randomly assigned to study and control groups. The study group went through 12 sessions of cognitive behavioral therapy; an overall 24 hours. The control group did not receive any special treatment. All the participants completed the self-efficacy questionnaire at the beginning and end of treatment. Analysis of covariance was used to analyze data. In a pilot project, 30 opiate-dependent clients of addiction clin- The findings showed significant differences in Novelty seeking, Harm avoidance, Persistence, Cooperativeness, Self-directiveness, and Self-transcendence between opiate and stimulant users. In all the abovementioned subscales the mean values of stimulants were higher than opiates. There were no significant differences in subscales of personality traits based on age. Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S69 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Conclusion Based on the mean values of the TCI, personality traits reflecting personality disorders are detectable and predictable in substance abusers. This is important in the prevention and treatment of addiction. Keywords Personality Disorders, Personality Traits, Temperament and Character Inventory, Opiate, Stimulants Teachers and Students’ Perspectives of the Contents of an Addiction-Prevention Curriculum Seyedeh Zainab Moosavi1, Mohammad Hasan Mirzamohammadi2, Omid Massah3 1. M.Sc. of Educaton, Shahed University, Tehran, Iran 2. Ph.D. of Islamic Education Philosophy, Associate Professor of Educaton Faculty, Shahed University, Tehran, Iran 3. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran Background and Aim To design appropriate content for an addiction-prevention curriculum from the viewpoint of teachers and students. Methods In this survey 370 male and female students and 210 teachers were selected from Hamedan’s high schools through clustered randomized sampling. Eventually, 363 students and 200 teachers participated in the study. Two researcher-made questionnaires were used for data collection. Data were analyzed with Chisquare, Friedman and independent T tests. Results The highest level of agreement reached on the content was on these skills, in order of importance: the ability to say ‘no’ to others’ unreasonable demands, awareness of how friends can influence the desire to start or avoid addiction, and the ability to make decisions and interact with others. There was no significant difference among the three factors of causes, harms and prevention and they were all reported to be of equal importance. However, having compared the means, significant differences were found between the two groups of teachers and students and also between males and females. 2. M.Sc. of Educaton, Shahed University, Tehran, Iran 3. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran Background and Aim The purpose of the present study was to investigate the extent the concepts of addiction were addressed in high school textbooks. Methods Descriptive methods were used to select the components of the concept of addiction, and content analysis was applied to analyze the book contents. The study population consisted of 61 high school books. However, 14 books were purposefully selected for this study. The data collection tool used was the content analysis checklist. The validity of the latter has been established by social and educational experts, and its reliability coefficient has been reported at 91% (calculated by Scott’s Formula). Sixty-seven components were identified and classified into three categories, namely, causes, harms and prevention of addiction. The units of analysis considered in this study included: statements, themes, examples, course topics, words, poems, illustrations, questions, tables and exercises. This research seeks to address these questions in the context of books: To what extent has focus been laid on the causes of addiction? To what extent has focus been laid on the harms of addiction? To what extent has focus been laid on the prevention of addiction? Results The concepts of addiction have been addressed 212 times in the textbooks under study. The frequency of each category addressed was: 52 (24.52%) for causes, 89 (41.98%) for harms and 71 (33.49%) for prevention. Conclusion Results demonstrate that little attention has been paid to the concept of addiction in high school textbooks, the majority of which was observed in biology textbooks (90 (42.44%) instances). Therefore, it can be concluded that only the biological aspect of addiction has been addressed, whereas its social, personal, familial and religious aspects have been largely neglected. Keywords Content Analysis , Addiction , Causes , Harms , Prevention , High school Conclusion Teachers and students believed that the inclusion of drug education in high school textbooks is important, especially regarding the topics agreed. Keywords Curriculum , Addiction , Prevention , Causes , Harms Content Analysis of the Concepts of Addiction in High School Textbooks MohammadHasan Mirzamohammadi1, Seyedeh Zainab Mousavi2, Omid Massah3 1. Ph.D. of Islamic Education Philosophy, Associate Professor of Educaton Faculty, Shahed University, Tehran, Iran The Role of Sensation Seeking and Coping Strategies in Predicting Addiction Potential among Students Omid Massah1, Younes Doustian2, Farideh HosainSabet3, Yousef Aazami4 1. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 2. Ph.D. Student of Rehabilitation Counseling, University of Social Welfare & Rehabilitation Sciences, Tehran, Iran 3. Ph.D. in Psychology, Assistant Professor of Allameh Tabataba’i University, Tehran, Iran 4. M.Sc. of Psychology, Allameh Tabataba’i University, Tehran, Iran S70 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Background and Aim This study examined the role of sensation seeking and coping strategies in predicting high school students’ drug addiction potential. Methods This study was of descriptive–correlational nature. Multi-stage cluster sampling was used to select 230 high school students in Kermanshah. To measure the variables, Zuckerman Sensation Seeking Scale (5th Form) (ZSSS), Coping Strategies Questionnaire (Billings and Moos), and the Addiction Potential Scale (Weed and Butcher) were used. Data were analyzed using Pearson’s correlation and multiple regression analysis. Results There was a significant relationship between sensation seeking and drug addiction potential among the students. Moreover, coping strategies could predict drug abuse potential, where emotionfocused coping was the most powerful predicting variable. Conclusion According to our results, those with a higher level of sensation seeking and those who use emotion-focused coping strategies are more prone to substance abuse. Keywords Sensation Seeking , Coping Strategies , Addiction Potential , Students The Efficacy of Problem Solving Training on Decreasing the Male High School Students’ Addiction Tendency Amin Khaje Mansouri1, Masoud G. Lavasani2, Elaheh Hejazi3, Mahdi Mazidi4, Mojgan Bakhshi Nodoushan5 1. Faculty of Psychology, University of Tehran, Tehran, Iran 2. Faculty of Psychology, University of Tehran, Tehran, Iran 3. Faculty of Psychology, University of Tehran, Tehran, Iran 4. Department of Clinical Psychology, University of social welfare and rehabilitation sciences, Tehran, Iran 5. Faculty of Psychology, Shahed University, Tehran, Iran Background and Aim The aim of the current study was to investigate the efficacy of problem-solving training on decreasing male high school students’ addiction tendency. Methods Results Data were analyzed through (ANCOVA) analysis. The results showed a significant difference between the pre-test and posttest scores of addiction tendency only in the experimental group (p<./001) with the efficacy coefficient of 0/55. Conclusion The results of this study provide a preliminary evidence of the efficacy of problem solving training on decreasing addiction tendency in high school students. Keywords Addiction tendency, High school students, Problem solving skills The Effectiveness of Group Behavioral – Cognitive Education on Self- Esteem and Way of Looking to the Opioid in Addicted People Referred to Health Welfare Addiction Center of Karaj Mohammad Mazloumi Rad1, Fatemeh Zalkan2 1. Research Center 2. Research Center Background and Aim The current study was done to investigate the effectiveness of group behavioral – cognitive education on self- esteem and way of looking to the opioid in addicted people referred to health welfare addiction center of Karaj. Methods The statistical society consist of all addicted people who referred to the health welfare addiction center of san for the first time that were ll0 people, after choosing to people who had low self-esteem and had positive looking to addiction were put in two groups of control and experiment. The theorical perspective- assessing questionouire (2001) and cuper smith (1967) one has been used to gather the data. Group behavioral – cognitive educational program has been done in twelve 1/5 hour session in experimental group and after finishing educational program, post test has been administered for both group and The results obtained were analyzed using statistical methods Mamco covariance. Results The method of the study was quasi-experimental with pre-test and post-test design and control group. A total of 129 first year high school students (aged between 15 and 16) were selected by multistage cluster random sampling method and completed Zargar’s (2006) “Iranian Addiction Potential Scale”. Based on the scores of the scale, 30 students who scored 2 standard deviation above the mean were selected. Those students were categorized into experimental or control groups (15 students in each group). The experimental group received 8 sessions (90 minutes each) of “problem solving skills training” (Dixon and Glover, 1984). The obtained results, by using Mamco covariance statistical seetor. Showed: according to the meaning of average differences, we express by 99% security, that the mentioned hypothesis, group behavioral cognitive education is effective on self esteem and perspective of addicted people referred to addiction center. Conclusion according to the calculated F meaning: - the amount of self esteem in the addicted people who are under group behavioral- cognitive education is different from the people who are not under group behavioral- cognitive education. - the perspective of the addicted people who are under group cognitive- behavioral edu- Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S71 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall A Comparison of Early Maladaptive Schemas in Smokers and Non-Smoker Individuals cation is different from the ones who are not under group cognitive- behavioral education. Keywords Cognitive Education- Group Behavior- Perspective Method – Self Esteem. Effectiveness of Cognitive-Behavioral Therapy (CBT) on Early Maladaptive Schemas, Quality of Life in Substance Dependents Masoomeh Mehrafarid1, Masoud Khakpour2 1. Counselor in Ministry of Education, Iran 2. Imamreza Iiternational University, Mashhad, Iran Background and Aim Drug use in the world today has become unsolvable problem. This study examined the effectiveness of CBT on early maladaptive schemas, quality of life and drug-related beliefs in substance dependents. Methods In a semi-experimental study, 36 subjects with diagnosis of substance dependency who successfully detoxified were divided into two experimental group (18 subjects) and control group (18 subjects) selected by available sampling method from MMT clinics (Group 1) and 32 subjects with diagnosis of substance dependency who successfully detoxified in QUCHAN prison were divided into two experimental group (16 subjects) and control group (16 subjects) selected by random sampling method (Group 2). The experimental groups received 12 sessions of CBT and the control groups did not receive any treatment. Overall 66 participants were asked to complete the Young Schemas Questionnaire-short form, EQ-5D questionnaire was used to evaluate the quality of life and morphine test before, after CBT treatment, and after a 3-month follow up stage. Data were analyzed using 12 test and covariance analysis. Results 12 test results showed that experimental and control groups had a significant difference in early maladaptive schemas, quality of life at periods of post test and follow up in group 1 and 2. Conclusion According to the findings CBT is effective in decreasing early maladaptive schemas and increasing quality of life in substance dependants an also it is effective in relapse prevention. Keywords CBT, Early Maladaptive Schemas, Quality of Life, Substance Dependants Sepideh Memarian1, Saeede Azaraeen 2 1. Master Degree from Ferdowsi University of Mashhad 2. Master Degree from Ferdowsi University of Mashhad Background and Aim Cigarette smoking continues to be the single greatest preventable cause of disease and death in the United States (U.S. Department of Health and Human Services, 2004). According to Beck’s (1976, 2005) cognitive theory of psychopathology, dysfunctional internal working models can best be considered as maladaptive schemas. Young (1995) revised the concept of maladaptive schemas into what he termed Early Maladaptive Schemas (EMS) that are “… extremely stable and enduring themes that develop during childhood and are elaborated upon throughout an individual’s lifetime” (p. 9) and are assumed to strongly guide the aberrant cognition, emotion, and behavior as seen in many types of psychopathology (Young 1994). The aim of present study was to examine the severity of reported maladaptive schemas in smoker individuals in comparison with non-smokers. Methods A total of 100 participants, comprising a smoker group (n = 50) and a non-smoker group (n = 50), were recruited. Young early maladaptive schemas questionnaire short form third revised (YSQ-S3) (Young 2005) was conducted. The YSQ-S3 is a 90item questionnaire measuring 18 maladaptive schemas. Each schema subscale comprises 5 items, rated on six-point scales. Higher mean scores indicate a greater presence of the particular maladaptive schema. Results Data were analyzed using one-way analyses of variance. The smoker group consisted of 50 men, with a mean age of 28.08 years (SD = 10.07, range 19–39 years). The mean age of nonsmoker group was 30.7 years (SD = 8.66, range 20–41 years) and consisted of 50 males. The results revealed that there were significant differences between both groups in early maladaptive schemas. As expected, the smoker group endorsed higher levels of maladaptive schemas in abandonment/instability (F(1.98)= 11.68; p= 0.001), mistrust/abuse (F(1.98)= 10.44; p= 0.001), emotional deprivation (F(1.98)= 6.23; p= 0.003), dependence/incompetence (F(1.98)= 19.59; p= 0.000), enmeshment/undeveloped self (F(1.98)= 23.78; p= 0.000), failure (F(1.98)= 14.28; p= 0.001), approval-seeking/recognition-seeking (F(1.98)= 9.47; p= 0.002), negativity/pessimism (F(1.98)= 16.78; p= 0.001), emotional inhibition (F(1.98)= 29.44; p= 0.000). Conclusion In cognitive theory, it is assumed that that each type of emotional disturbance is related to a unique cognitive profile characterized by specific cognitive content (Beck 1976). In this study, it was demonstrated that smoker people display significantly higher schema scores compared to the non-smoker group, and schema scores can discriminate reliably between these groups. The find- S72 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall ings provided empirical support for the proposition that early maladaptive schemas may influence on tendency of smoking. The present results are consistent with Beck’s content-specificity hypothesis, which suggests that psychological disorders and states ought to be differentiated by the content of their cognitive associates (Beck, 1976; Beck & Emery, 1985; Beck, Rush, Shaw, & Emery, 1979). In conclusion, these findings are in line with assumptions within cognitive theory on the dimensionality of the schema concept, on the positive association of maladaptive schemas and psychopathology, and on maladaptive schemas as a vulnerability factor for the development of psychological symptoms and obviously these findings have important clinical implications. Keywords Farzad Jalilian1, Mehdi Mirzaei Alavijeh2, Behzad Karami Matin3, Ahmad Ali Eslami4, Mohamad Reza Amoei5, Seyyed Nasrollah Hosseini6 1. Substance Abuse Prevention Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran 2. Substance Abuse Prevention Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran 3. Substance Abuse Prevention Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran 4. Department of Health Education and Promotion, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran. 5. Applied Research Bureau of the Police of Kermanshah, Iran. 6. Ministry of Health and Medical Education, Tehran, Iran Background and Aim Early Maladaptive Schemas, Smokers, Non-Smokers. The Effect of Problem Solving Intervention on Aggression and Craving Substance Abusers Samira Mesmarian1, Ebrahim Shakeri Motlaq2, Hossein Molavi3, Felora Unesi4 1. M.A Olum Tahghighat Fars University 2. M.A Olum Tahghighat Fars University 3. PhD Isfahan University 4. PhD Isfahan University Background and Aim The most tragic that addiction has brought to human society has been distraction of the fiber of family.the most noticeable problem of substance abusers are aggression and craving. The purpose of this study was to determine the effect of problem solving on aggression and craving in addicted subjects. Methods Research was carried out in the frame of a quasi- experimental design with pre-test and post-test assements.Therefor 20 addicted subjects were randomly selected and assigned to the training and control groups. The Aggression Questionnaire and Craving Beliefs Questionnaire were administered as the pre- post & followup tests. After the pretest the training group received 8 sessions (90 minutes each) of problem solving training. The follow-up test was administered one month after the end of training Results The results of analysis of covariance showed that the means of scores of the training group were significantly reduced as compared to the control group on aggression and craving both in the post-test and follow-up. Conclusion The problem solving skill has been greatly useful to control their aggression and craving for substance abusers Keywords Prevalence of Marijuana use among Adolescents in Kermanshah County Addiction, Aggression, Crating, Problem Solving Training Marijuana use especially among the adolescents is common; which could be a particularly negative impact (such as: spending less time studying, cognitive impairment, difficulty concentrating, missing classes) on the lives of adolescents. The aim of this study was determination of prevalence of marijuana use among sample of boy adolescents in Kermanshah County. Methods This cross sectional study was carried out among 163 adolescents of Kermanshah County, which recruited with a random sampling method. Participants filled out a self-administered questionnaire. Data were analyzed by SPSS-20 using logistic regression statistical tests at 95% significant level. Results The mean age of respondents was 16.92 [SD: 1.22], ranged from 15 to 19 years. Almost 3.4% of the participants last one marijuana use in lifetime. Logistic regression showed; parent divorce (OR = 3.276), unprotect sex (OR = 4.252), and ecstasy use (OR = 9.186) were the more influential predictor on marijuana use. Conclusion Comprehensive preventative health education programs need to emphasize on psychological factors that mediate and predict adolescents’ and youths health-related behaviors; Regarding the absence of study of cognitive factors related with marijuana use in Iran, we suggest the designing theory based studies to determined cognitive factors related with marijuana use among Iranian boy adolescents. Keywords Adolescents, Marijuana, Prevalence. Cigarette Smoking, Psychotropic Drug use and Alcohol Drinking among College Students: Investigation the Role of Sensation Seeking Farzad Jalilian1, Mehdi Mirzaei Alavijeh2, Behzad Karami Matin3, Mohammad Ahmadpanah4, Ahmad Ali Eslami5 1. Substance Abuse Prevention Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran 2. Substance Abuse Prevention Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S73 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall 3. Substance Abuse Prevention Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran 4. Research Institute of Behavioral Disorders and Substance Abuse, Hamadan University of Medical Sciences, Hamadan, Iran. 5. Department of Health Education and Promotion, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran. Background and Aim Sensation seeking is a character, and several study indicated sensation seeking is related with a many of illegal and risky behaviors. The aim of this study was determination prevalence of cigarette smoking, psychotropic drug use and alcohol drinking and associated with sensation seeking among sample of Iranian male medical college students. Methods A cross-sectional study was conducted among 425 male medical college students, during 2014 which was randomly selected with the proportional to size among different faculty. A standard selfreport questionnaire was applied for collecting data and data were analyzed by SPSS-20 using logistic regression statistical tests at 95% significant level. Results 29%, 1.1%, and 13.5% of the respondents reported that last one cigarette smoking, psychotropic drug use and alcohol drinking in lifetime, respectively. Logistic regression showed, sensation seeking was a predict cigarette smoking (OR=1.154), psychotropic drug use (OR=1.314) and alcohol drinking (OR=1.903). Conclusion Based on our result, it seems that designing and implementation of educational programs to reduce negative sensation seeking among the young adults may be useful of the results in order to prevent of substance abuse. Keywords Cigarette Smoking, Psychotropic Drug, Alcohol Drinking, College Students, Sensation Seeking. An Overview of the Causes and Consequences of Addiction in Women with Social Approach Iran ghazi1, Fereshteh Mirzazadeh2, Farhad Hadinejad3 1. Academic Staff :Science Affiliation Research Institute of ShakhesPajouh, Isfahan, Iran. 2. crisis management PhD student, :Science Affiliation Research Institute of ShakhesPajouh, Isfahan, Iran. fereshtehmirzazadeh@yahoo.com 3. Department of Industrial Management, Faculty of Management and Accounting, Allameh Tabataba’i University, Tehran, Iran. Email: farhad_hdng@yahoo.com Background and Aim Growing trend of addiction, particularly in women and increased risk of cortical damage in the community,made us to the review of research and analysis conducted in this field to examine the causes and consequences of social approach and provide guidelines for the prevention and treatment. Methods We try to find the social roots of addiction in women And treat ways by surving and reviewing of existing research and relevant theories. Results Women’s Addiction is a social issue, which is needed to make informed and activation of different sectors of society. To Prevent and treat for the immediate With the help of measures such as counseling and treatment centers for women And culturing and increasing public awareness. Conclusion Growing trend of addiction, particularly in women and increased risk of cortical damage in the community,made us to the review of research and analysis conducted in this field to examine the causes and consequences of social approach and provide guidelines for the prevention and treatment. Framework of research has been performed on social issues, addiction in women and research and analysis in this field. We try to find the social roots of addiction in women And treat ways by surving and reviewing of existing research and relevant theories. Women’s Addiction is a social issue, which is needed to make informed and activation of different sectors of society. To Prevent and treat for the immediate With the help of measures such as counseling and treatment centers for women And culturing and increasing public awareness. Keywords Drugs, Addiction, Addicted Women, Social Deviations, Prevention and Treatment. Burden of Drug and Alcohol Use Disorders in Iran: Findings from the Global Burden of Disease Study 2010 Babak Moazen1, Mostafa Shokoohi 2, Atefeh Noori 3, Shadi Rahimzadeh 4, Sahar Saeedi Moghaddam 5, Farshad Farzadfar 6 1. Non-communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran. 2. Regional Knowledge Hub, and WHO Collaborating Centre for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran. 3. Non-communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran. 4. Non-communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran. 5. Non-communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran. 6. Non-communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran. Background and Aim Due to the specific socio-cultural and geographical situation, drug and alcohol use are among the most important health problems in Iran. The current study is aimed to report the burden of substance and alcohol use disorders in Iran, compare the measures with the Global Burden of Disease (GBD) results, and evaluate the weaknesses and challenges involved in GBD project. S74 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Methods The result presented in this paper is a part of the GBD project conducted by the Institute for Health Metrics and Evaluation in 2010. The burden of substance and alcohol use disorders in Iran has been evaluated in terms of disability-adjusted life years (DALYs); years of life lost to premature mortality (YLLs), and years lived with disability (YLDs) for the years 1990, 2005, and 2010. Results Death rates per 100,000 found to be 7.7 and 0.16 for men, and 0.62 and 0.02 for women, attributable to drug and alcohol use disorders, respectively. YLL rates per 100,000 were 351.8 for men and 24.8 for women attributable to drug use disorders, and 5.8 for men and 1 for women attributable to alcohol use disorders. YLD rates per 100,000 found to be 452.6 for men and 202.1 for women attributable to drug use disorders, and 105.8 for men and 23.7 for women, related to alcohol use disorders. DALY rates per 100,000 attributable to drug use disorders were 804.5 for men and 227 for women, while these rates were 111.7 for men and 24.7 for women, related to alcohol use disorders. Results The results showed that these variables (perceived social support, attachment styles, coping styles and personality traits) can predict the membership in addict and non-addict groups of alcohol in boys adolescents. The 12 predictive variables accounted for 57/8% of the variance between addict and non-addict groups of alcohol. In stepwise discriminatory model, 82% of participants were categorized in addict and non-addict group correctly. Conclusion The result indicated that perceived social support, attachment styles, coping styles and personality traits can discriminate between addict and non-addict groups of alcohol. Keywords Perceived social support, Attachment styles, Coping styles, Personality traits, Alcohol, Adolescent boys Therapeutic Role of the Holy Quran Recitation in Empowering Withdrawal Mansoor Darvishi Tafvizi1, Sara Moghaddam2 1. Jahrom University Of Medical Sciences 2. Jahrom University Of Medical Sciences Conclusion Burden of drug and alcohol use disorders in Iran is mostly related to men than women, which demonstrate the importance of more attention to men to mitigate the burden of the above-mentioned disorders in Iran. Higher burden of drug than alcohol dependence disorders also doubles the importance of urgent interventions among this core group in Iran. Keywords Substance-Related Disorders, Alcohols, Burden, Iran Predicting the Membership of Adolescents in Addict & Non-Addict Groups of Alcohol According to Perceived Social Support, Attachment Styles, Coping Styles and Personality Traits Nahid Mofradnejad1 1. Shahid Chamran University, Ahwaz Background and Aim The purpose of the current research was to indentify the role of perceived social support, attachment styles, coping styles and personality traits in discriminating between addict and non-addict groups of alcohol. Methods In this causal-comparative study, 50 addict boys of alcohol (age between 17-19 years old) and 50 non-addict boys (17-19) were selected by available sampling. All the participants were evaluated by Perceives Social Support Questionnaire (MSPSS), Adult,s Attachment Styles (AAI), Coping Stress Questionnaire (CSQ) And NEO-FFI. Data was analyzed by SPSS-16 software and discrimination analysis method was used. Background and Aim Quran; the greatest miracle of the universe, is a book that has profound content and healing power. Quran is not only a source of peace, comfort and hope, but also a source of healing and mercy for the believers. Healing of this scripture has different aspects. One of them is voices and sounds of Quran, which can be healing many diseases. Addiction is a disease in health scope that has injured mental dimension of patient in addition to physical. Therefore, based on the Holy Quran and its miracle of healing scope and also researches in similar disease can proposed Quran recitation as an effective way to supplement addiction treatment and withdrawal in this innovation research, explicitly. Methods This study has been conducted with two methods; systematic review of articles and laboratory research based on fundamental research approaches. acoustic signals analytic tests is used and the effect of the Holy Quran recitation on addiction treatment and withdrawal is validate with a review of the scientific credible evidences and research information, in this experimental study. Results Quran voices, has music and harmony of the song that affect on the meaning of words and phrases in the Quran. Vocal communication with the meaning (Phone-semantic) and acoustic signals with the natural sounds of similar frequency analysis was investigated by specialized software. After this stage and proven effective of Quran in an experimental study and considering its information on drug addiction treatment, surprisingly healing of Quran was appearing. Quran recitation or hearing can impact on the body and helps to flush out toxins and increase physical power in addition to the effect of increased determination, mental powers, patience and struggle against withdrawal pains and not using drugs, as Imam Sadeq (AS) has said. Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S75 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Conclusion Recitation and hearing the Holy Quran, is preface the remembrance of Allah that is beginning of growing season in human life. Quran integrated of human body and soul, in addition to meditate on its verses, can also be the result of Quran voices. In this study after reviewing the findings, the efficacy of Quran as complementary treatment in increasing the power of quit drugs was proven. Keywords The Holy Quran, Quran Voices, Addiction Treatment, Withdrawal Effectiveness of Guided Adolescent Problem Solving on Craving, Attitude Toward Drug Abuse and Coping in Substance Abusing Adolescents Leila Mohamadi , Parvane Mohamadkhani , Hadie Mehrazar , Masoome Taghizade4 1. Addiction Study Center of University of Social Welfare and Rehabilitation Sciences 2. . PhD of Psychology. Manager of Psychology Group in University of Social Welfare and Rehabilitation Sciences 3. PhD of Psychology 4. M.S of Psychology 1 2 3 Background and Aim This study considering the effectiveness of Guided Adolescent Problem Solving on craving, attitude toward drug abuse and coping in Substance abusing adolescents. Methods A quasi-experimental design with pre-test, post-test was used. The statistical population was 250 adolescents who because of their delinquent behaviors were referred and just 42 of adolescents had have drug abuse about one years that 30 of them who aged 1420 were randomly selected. They were randomly assigned to two control and experimental groups. Participants in both groups were assessed by drug craving Inventory, attitude toward drug use questioner and coping skills questioner and also structured clinical interview to diagnose if they receive full criteria of substance abuse. Then, experimental group proposed with Guided Adolescent Problem Solving intervention for five session every week. Three week after last session performanced post test for both of groups. The Effectiveness of Group Cognitive Behaviour Therapy on Drop-Out Prisoner Addict People Mohidine Mohamadkhani1, Goona Fathi2 1. Kermansh University 2. Kermansh University Background and Aim Nowadays addiction is one of the complicated in human communities kills many people annual and one of this paper is The effectiveness of group cognitive behaviour therapy on drop-out prisoner addict people. Methods This research is semi-experimental and the pre test-post test project is with control group. The society of this research consists of 400 drop-out addict persons. In central prison of Kermanshah. We selected randomly 40 of them which were divided into two identical number of 20 persons then both of these group were pre-test with beck depression Inventory Experimental group was tested with cognitive behaviour therapy during 12 sessions. After interventions both of two groups were post-test. By use of descriptive statistic method mean and standard deviation and to assess the theory we utilized the inferential statistic correlated T to compare in groups and independent T to compare two groups. Results Results showed that the group was intervened their depression mark had diminished significantly and research theory was confirmed about 5 percentage Conclusion Considering the results we concluded effectiveness of group cognitive behaviour therapy reduces the depression among addict people. Keywords Cognitive Behaviour Therapy, Depression, Addict Drug Testing in Schools Mohidine Mohamadkhani1, Goona.Fathi2 1. Kermansh University 2. Uromia University Results The experimental group showed a meaningfull clinical change on craving and drugs belief and meaningfull statistical change in their emotional express as a way of coping. Conclusion Guided Adolescent Problem Solving is an effective intervention on adolescents with drug abuse and could be useful to help them to improve their coping style. Group Interventions which are specified for adolescents have better consequent for treatment of substance abuse. Emotion expression has critical role in reduse of craving and drug abuse believes. Keywords Guided Adolescent Problem Solving, Drug Abuse, Craving, Believes, Coping Skills. Background and Aim Drug Testing in Schools vii ABSTRACT Despite considerable recent public and judicial attention to the issue of drug testing, little empirical research has focused on the relationshi p between drug testing in schools and the actual use of illicit drugs by students. Methods To explore this issue, we use school -level survey data about drug testing from the Youth, Education, and Societ y study and student-level survey data from the same schools participating in th e Monitoring the Future study. Us ing cross-sectional data, we ex- S76 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall amine how the presence of drug testing relate s to 12-month use of marijuana and 12-month use of any other illicit drugs by student Results The extended findings continue to show th at (a) relatively few schools report testing students for drug use, (b) there is little evidence of a time trend in the prevalence of student drug testing in schooln American schools between 1998 and 2010 Conclusion More high schools than middle schools reported the use of drug testing, and (d) most school s that test students repor t that the testing is “for cause.” Of most im portance, drug testing still is found not to be asso ciated with students’ reported illicit drug use—even random testing th at potentially subjects the entire student body. Testing was not found to have significant associa tion with the prevalence of drug use among the entire student body nor the prevalence of use am ong experienced marijuana users. Analyses of male high school athletes found that drug testing of athlet es in the school was not associated with any appreciably different levels of marijuana or other illicit drug use. Cr oss-sectional data were of necessity used in these analyses.we believe the findings to be buttressed considerably by the fact that st atistical controls were used fo r a number of known important risk factors for drug use, which s hould control for most pre-ex isting differences; and still no statistically significant differences emerged. Ne vertheless, prospective studies would make a stronger case. Policy implic ations are discussed. Keywords Addiction, School, Drug Conclusion Only a minority of people in DSM-5 AUD remission relapsed, but the risk of relapse increased substantially with the presence of at least one of the risk factors. Moreover, at-risk current drinking coupled with other risk factors substantially increased the likelihood of relapse. Therefore, current drinking may provide an adequate reference point for relapse prevention. Keywords Alcohol Consumption, Alcohol Use Disorder, DSM-5, Relapse, Symptoms High Purity Heroin Use Among Women in Karaj, Iran: a Pilot Study Mohidine Mohamadkhani1, Goona.Fathi2 1. Kermansh Payamnoor University 2. Uromia University Background and Aim High purity heroin use is a new epidemic health concern among Iranian drug-using women in recent years. However, the nature and initial factors associated with this serious health problem have not been studied yet Methods Desipramine Enhances the Ability of Risperidone to Decrease Alcohol Intake in the Syrian Golden Hamster. Mohidine Mohamadkhani1, Goona.Fathi2 1. Kermansh University 2. Uromia University Background and Aim Alcohol consumption and symptoms as predictors for relapse of DSM-5 alcohol use disorder. To understand this issue, a cross-sectional study was conducted and sixty treatment and non-treatment seekers who met the Diagnostic and Statistical Manual of Mental Disorders, 4(th) ed., Text Revision (DSM.IV-TR) criteria for drug dependence with mean age of 28.7 (± 8.3) years were recruited from 16 addiction clinics and drop-in centers (DICs) in Karaj, Iran. First, demographics, and details of drug use and risky behaviors were collected based on items elicited from Addiction Severity Index (ASI). Then, initial factors associated with high purity heroin use were collected by interviewing and applying a researcher-made questionnaire. Data was statistically analyzed by descriptive methods of statistics, chi-square, and Student’s independent t-test in SPSS software Results Methods Data are from the Netherlands Mental Health Survey and Incidence Study-2 (NEMESIS-2). We selected 506 people in ≥12-month DSM-5 AUD remission at baseline and assessed their status at 3-year follow-up. AUD symptoms and drinking patterns were assessed using the Composite International Diagnostic Interview 3.0. Time since remission was assessed retrospectively at baseline and ranged from 1 to 48 years. Predictors for relapse were examined using Cox regression analysis Results (≥29/43) past alcohol intake, 6+ lifetime AUD symptoms, ‘impaired control over use’, and at-risk (≥8/15) current intake. The risk of relapse was especially high when medium or high past intake or 6+ lifetime symptoms coincided with current at-risk drinking. Umulative AUD relapse rate was 5.6% at 5 years, 9.1% at 10 years and 12.0% at 20 years. Relapse was predicted by both medium (15-28/22-42 drinks weekly for women/men) and high Initiation of high purity heroin use was facilitated by family/ relatives factor (66.7%), curiosity (60.1%), peers (54%), desire to experience rapid physical effects of high purity heroin compared with other opioids (50.1%), and treatment of general medical problems such as colic pain (33%). Chi-square test showed that non-treatment seekers were younger (less than 35 years) (66.6% vs. 56%, p ≤ 0.001) and mostly living with drug-dependent friends (26% vs. 3.3%, p ≤ 0.001) compared with treatment seekers. No relation was found among other factors. Conclusion Factors facilitating the initiation of high purity heroin use revealed in this study have not been fully addressed by current drug Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S77 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall treatment services in Iran. To design comprehensive treatment programs, further studies on larger samples with more women are necessary. Declaration of interest: None Keywords Etiology, High Purity Heroin, Treatment, Women Drinking Motives in the Prospective Prediction of Unique Alcohol-Related Consequences in College Students Mohidine Mohamadkhani1, Goona.Fathi2 1. Kermansh Payamnoor University 2. Uromia University Background and Aim Although college students experience a diverse range of alcohol consequences, most studies focus on global, rather than distinct, consequence types. One predictor of unique consequences-drinking motives-has been studied only cross-sectionally. We aimed to examine the prediction of unique alcohol consequence domains (social/interpersonal, academic/occupational, risky behavior, impaired control, poor self-care, diminished self-perception, blackout drinking, and physiological dependence) by coping and enhancement motives over the course of one year. We hypothesized that coping motives would directly predict and that enhancement motives would indirectly (through alcohol use) predict unique consequences Methods Web surveys were administered to a sample of college students (n = 552, 62% female) at the beginning of the fall semester for 2 consecutive academic years. Structural equation modeling was used to test direct and indirect paths from motives to consequences. Results The data supported hypothesized direct, prospective paths from coping motives to several alcohol consequences (impaired control, diminished self-perception, poor self-care, risky behaviors, academic/occupational, and physiological dependence). These associations were not mediated by alcohol consumption. Enhancement motives were indirectly associated with all eight consequence domains by way of increased alcohol use at follow-up. Models were invariant across gender, year in school, and symptoms of posttraumatic stress Conclusion Findings suggest that whether motives act as a final common pathway to problem drinking may depend on which motives and which drinking outcomes are examined. As coping motives demonstrate a direct link to unique alcohol problem types over time, individuals endorsing these motives may need to be prioritized for intervention. Keywords Alcohol-Related Consequences , Addiction The Impact of Urbanization and Socialize with Oppositional Groups and Trends in Youth Drug LENGEH City Fatemeh Mohamedi1 1. Master of Clinical Psychology, University of Kish International and High School Counselor – Bandar lenghe – Iran. Background and Aim Social psychologists close to pressures from groups such as family and peer into a person will have great significance and by comparing two groups of values and norms influence and pressure from family and peers in their studies, the influence of most norms Show said. Obviously too young for the group with values and norms, are under pressure. Sometimes norms and values of the two groups together and coordinates are sometimes in conflict, however, both the color to become under pressure to make young. The aim of this study was to identify factors affecting youth drug trends and offers ways to reduce their tendency to drug abuse have been conducted, Researchers regarding the role of family members and close relatives, the tendency for young people to socialize with friends, drug addiction and norm-breaking effects are very stressed. Methods This cross - sectional analytic study. Data from a total of 99 young people addicted males in the age group below 25 years, were selected by random sampling. In order to compare the 99 non-addicted young people in terms of gender, age, education and place of residence, were matched to a comparison group participated in the test. Results Based on the findings, the average age of drug users surveyed 39/29 years of age onset of substance use 7/16 years. The results indicate that among the relatives of the young addict, 6/60 percent were drug addicts, while the control group list 4/40 percent was achieved. Meanwhile addicted youth surveyed, 1 / 12% of fathers and 1/11 percent were addicted brother. But only 1 percent among non-drug-addicted father and brother were reported. Average number of smoking friends, friends and friends of addicts, thieves or drug addicts among the young people 38/7, 31/4 and 08/2 was estimated that, compared with the control group (54/1, 19/0 and 04/0 ), significant differences were observed. The exciting thing is that 6/64 per cent said they were addicted the first time it has been offered drugs by friends. More importantly, the 9.87 percent Non-addicted youth with no consort addicted friends who have not been socialized, while the 9/89 per cent of young people said that drug addicts are addicted to a friend. Conclusion The research has shown that teens who are addicted parents have got far more drugs. Also, the role of friends and peers in adolescent drug addiction as one of the factors to be considered. Keywords Addiction, Young, Friends, Orientation, Norm, Norm-breaking S78 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall The Effectiveness of Cognitive Behavioral Therapy for Stress Management on the Recurrence Prevention of Drug-Dependent Men. Babak Mohammadi1, Amir Ahmadi2, Shiva Sadeghzadeh3, Hafez Atapour4 1. Master of Clinical Psychology, Islamic Azad University of Ardabil Science and Research Branch. Young Researchers And Elite Club, Tabriz 2. Master of Clinical Psychology, Islamic Azad University of East Azarbayjan Science and Research Branch. Young Researchers And Elite Club, Tabriz 3. Master of General Psychology Islamic Azad University of Uromiye 4. Master of Clinical Psychology, Islamic Azad University of East Azarbayjan Science and Research Branch. Young Researchers And Elite Club, Tabriz Background and Aim The present study aimed to assess the effectiveness of stress management therapy cognitive behavioral on recurrence/ relapse prevention in drug-dependent men. Out of random sample of 120 subjects ( 60 were addicts and 60 were non-addicts) the attachment style questionnaire and hardiness were studied Results The result showed that: there was a significant difference between addicts and non-addicts in terms to attachment styles. there was a significant difference between addicts and non-addicts regarding hardiness. there was no significant relationship between hardiness and attachment styles in addicts . there was no significant relationship between hardiness and attachment styles in nonaddicts people. there was significant difference on avoidance and secure components and commitment construct between addicts and non-addicts. Conclusion At last the research showed that attachment styles and hardiness in subjects relatd to substance abuse of them significantly Methods In a pilot project, 30 drug-dependent persons who were resident in the therapeutic community center of Tabriz were randomly assigned to two groups, experiment (n = 15) and control (n = 15) groups, then, were tested. The experimental group received 10 sessions of 90-minute stress management cognitive behavioral therapy. The control group did not receive any special treatment. All participants in the study were tested at the beginning, end and after the treatment by urinalysis. Statistical methods, descriptive and chi-square test were employed for data analysis Results The result showed no significant different between the experimental and control groups relating to the rate of recurrence in aftertest phase. But the rate of relapse in prevention phase in control group was significantly more than that of in experimental group. Conclusion According to the findings, we can conclude that the stress management therapy cognitive behavioral therapy is an effective way in prevention of relapse in dependent men. Keywords Cognitive Behavioral Therapy, Stress Management, Relapse/ Recurrence, Drug Dependency Relationship Between Substance Abuse with Attachment Styles and Hardiness between Addict and Non-Addict People of Sari Ebrahim Mohammadian Akerdi1, Hoda Babaei Kafaki2 1. Psychology Group, Islamic Azad University Neka Branch 2. Psychology Group, Islamic Azad University Sari Branch Background and Aim Methods The aim of this study was to examine the relationship between substance abuse on the one hand and attachment styles and hardiness on the other hand Keywords Substance Abuse, Attachment Styles, Hardiness, Addict Capacity Building: a Model for Enhancing the Capabilities of Actors Involved in Community-Based Processes Seyed Babak Moosavi Nejad1, Shahryar Rahmani2, Zahra Esfehani3 1. Baznegar Moaser Institute of Development Studies 2. Baznegar Moaser Institute of Development Studies 3. Bureau of Addiction Prevention of the Well-Being Organization Background and Aim This article aims to present the case for implementing a capacity building programme in place of a conventional training programme. The advantages and effectiveness of the two approaches are therefore also compared. In spite of the long history of training in development, one of the more debatable topics has always been the effectiveness of training programmes. This has led to doubts regarding the trend and methods of training. In this article, it is explained that capacity building is more than mere training. Throughout the 90’s, capacity building came to be used as a comprehensive term to describe a sustained enhancement of the competency and problem-solving abilities of people and institutions. However, in order to be effective, a capacity building programme or process has pre-requisites. These are also assessed in this article. Methods The capacity building programme implemented for the staff of addiction prevention bureau aimed to establish a learning approach amongst individuals and groups, so that they can gradually gain the capacity to learn from the diverse situations they find themselves in and to be able to plan for appropriate action. The basis for the capacity building programme was for the participants to reflect upon their own activities and to extract lessons and principles for their future activities. This six-month capacity building programme comprised of meetings, practical work and activities Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S79 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall to be carried out in between the meetings. The intended methodology was experiential learning, an iterative and cyclic process of action-reflection-action. It was expected that after each experience the participants would be equipped with a new and more transparent perception of how to implement and support participatory and community-based processes in their own environments. Results One of the more significant findings of this programme were the driving and prohibiting factors that affect the implementation of a capacity building programme. The participants’ understanding of these are touched upon in this article. In some of the provinces there was also an opportunity to evaluate the capacity building process in terms of its relevance to the participants real working environments, as well assessing the requirements of implementing a capacity building programme at community level. Conclusion The more the participants could work together as teams in their practical field work, the more it could be expected that the practical work be more multi-dimensional. Also, like any learning process, the speed, quality and lessons of a capacity building process depend to a great extent on the trust and motivation of the participants with respect to the process and the facilitating team. Finally, in terms of opportunities for joint learning, probably nothing can be as effective as the participants reflecting together on their practical field work. Reflection can be considered as the main component of a capacity building programme. Keywords CRF1 Receptor As a Novel Target for substance Addiction Treatment Mohammad Javad morabbi , Mohsen Roshanpajouh 1. no affiliation 2. State Welfare Organization of Iran Background and Aim Methods systemic review Results Stress system play important role in addiction Conclusion Capacity Building, Training, Community-Based 1 thalamic CRFsystems are activated during acute withdrawal from all major drugs of abuse in animal models, and central infusion of non-peptide CRF antagonists block the anxiogenic-like responses observed during acute withdrawal from drugs of abuse, including cocaine, alcohol, nicotine and cannabinoids. Similarly, systemic administration of blood–brain-barrier-penetrating CRF1 antagonists reduced the anxiogenic-, aversive- and hypohedonic-like effects of withdrawal from opioids, nicotine, benzodiazepines and alcohol. Moreover, the decreased brain reward function associated with drug withdrawal is CRF1 receptor-dependent. Elevation of reward thresholds during nicotine withdrawal is blocked byCRF1 antagonists. As above evidences CRF1 receptore probabely is a novel target for substance addiction treatment. At the present time GlaxoSmithKline and NIH are collaboratively evaluating verucerfont(An Anti-CRF1) for its ability to reduce stress-induced alcohol craving in anxious, stress-reactive alcoholic women (NCT01187511). Similarly, a comprehensive collaboration of Bristol Myers Squibb and NIH is currently testing oral daily pexacerfont(An Anti-CRF1) for its efficacy to prevent: (1) stressinduced craving for palatable food in dieters (NCT01656577), (2) stress-induced craving for tobacco in smokers attempting to quit (NCT01557556), and (3) stress- or alcohol cue-induced craving in anxious, alcoholic women (NCT01227980). 2 Drug addiction has been conceptualized as a chronically relapsing disorder of compulsive drug seeking and taking that progresses through three stages: binge/intoxication, withdrawal/negative affect, and preoccupation/ anticipation. Drug addiction impacts multiple motivational mechanisms and can be conceptualized as a disorder that progresses from positive reinforcement (binge/intoxication stage) to negative reinforcement (withdrawal/negative affect stage). The construct of negative reinforcement is defined as drug taking that alleviates a negative emotional state.one hypothesis is that the negative emotional state that drives such negative reinforcement is derived from dysregulation of key neurochemical elements involved in the brain stress systems within the frontal cortex, ventral striatum, and extended amygdala. Specific neurochemical elements in these structures are CRF, Dynorphine and NE.Additionally, Excessive drug taking engages activation of CRF not only in the extended amygdala, accompanied by anxietylike states, but also in the medial prefrontal cortex, accompanied by deficits in executive function that may facilitate the transition to compulsive-like responding. both the HPA axis and extrahypo- CRF1 receptor is an important and novel target in addiction treatment Keywords CRF1 receptor , Antagonist ,Addiction Microinjection of the Orexin 2 Receptor Antagonist into the CA1 is Partially Attenuated the Lateral Hypothalamus Stimulation-Induced Conditioned Place Preference Marzieh Moradi 1, Amir Haghparast 2, Zahra Fatahi 3, Abbas Haghparast 4 1. Neuroscience Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran 2. Faculty of Dentistry, International Branch of Shahid Beheshti University of Medical Sciences, Tehran, Iran 3. Neurobiology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran 4. Neurobiology and Neuroscience Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran Background and Aim Evidence from animal models suggests a role for orexins in reward processing and drug addiction. The lateral hypothalamus (LH) orexin neurons send projections to the CA1 region of the hippocampus which is believed to play a pivotal role in reward processes. In this study, we evaluated the role of orexin 2 receptor S80 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall (Ox2r) in the CA1 in the development of LH stimulation-induced conditioned place preference (CPP). Methods Animals weighing 220-280 g were unilaterally implanted by two separate cannulae into the LH and CA1. The CPP paradigm was done; conditioning scores and locomotor activity were recorded by Ethovision software. Carbachol (62.5, 125 and 250 nM/0.5 µl saline), as a cholinergic agonist, was administrated into the LH during conditioning phase to evaluate its effects on CPP induction. Intra-CA1 administration of TCS OX2 29 as a selective Ox2r antagonist (1, 3, 10 and 30 nM/0.5 µl DMSO) just 5 min before carbachol microinjection (250 nM; the most effective dose) during the 3-day conditioning phase was done to investigate the role of this type of receptor in the LH stimulation-induced CPP. Results Our findings showed that intra-LH administration of carbachol during conditioning phase induced CPP in a dose-dependent manner. The Ox2r antagonist could attenuate the conditioning scores related to the LH stimulation significantly (P<0.01). Conclusion The results suggested that orexin signaling within the CA1 is involved in the development of CPP induced by chemical stimulation of LH and Ox2 receptors in the CA1 region of the hippocampus have a partial role in this phenomenon. Keywords Reward; Lateral Hypothalamus; CA1 Region of the Hippocampus; Orexin 2 Receptor; Conditioned Place Preference; Rat Investigation of the Causes of Addiction in Patients Birjand Prison in 1392 Iman Mosaiy1, Iman Moosaie2, Zahra Karimi3, Side Zahra Tabatabayifar4, Aazam Majdi5 1. Birjand University of Medical Sciences 2. Birjand University of Medical Sciences 3. Birjand University of Medical Sciences 4. Birjand University of Medical Sciences 5. Birjand University of Medical Sciences Background and Aim Addiction is one of the phenomena of social evil. Have adverse effects on the lives of not only the addict but also the family and relatives of addicts at risk of multiple injuries this social phenomenon on. According to official statistics, nearly three percent of the total population suffering from some form of addiction Thus the study of the causes of drug addiction can be an effective step to prevent the big problem is our society that this study investigates the causes of drug addiction in the city of Birjand spent in prison. Methods In this cross-sectional analytic study on 186 male prisoners addicted to prison in the fall of 1392 was done. Samples using systematic random sample was selected from among male prisoners addicted Birjand Prison And to collect data through questionnaires, based on the design goals was used Its content validity was confirmed by a number of faculty experts. Students trained health questionnaire and interviews with prisoners was completed. Data were collected and analyzed by Spss software. The study of ethical issues in coordination with the General Directorate of Prisons city was conducted. The questionnaire was anonymous and Family moan. Results This study was conducted on 186 male addicts in the city jail. The mean age of participants was 33/5±13/4 years. In terms of education, 47/9% of primary school education or less, and only 7/9 percent had a college education. 55/8% married, 37% single, and the rest were divorced or widowed. 72/3% of urban and 27/7 percent were from rural areas. 58/6% of smoking and 56/6% of ever smokers. The most common form of addiction in the deal was Inhalation, with the 25/9 percent and intravenous drug with 8/6% of the cases belonged to the lowest. The most commonly abused substance in opium (23/5) percentage was determined. 51/1 of the history of alcohol use and 71/5 percent had a history of smoking hookah. The first drug consumption among the subjects with the highest prevalence of smoking by 47/6, respectively. The first time a friend (55/4%) of the drug to have a compliment. Most people tend to cause addiction, lack of parental control with 14/7 percent were. Most social causes of addiction-related jobs with no job and 19/1 respectively. According to respondents not having a job (81 percent) due to their tendency to addiction. While having fun (73/8 percent) were diagnosed as one of the important causes. 65/6% of people have access to drugs as well as very comfortable. Conclusion Considering the high prevalence of drug use, alcohol and other substance use opium as the most important drug consumption and Due to the lack of control in addiction and families of prisoners, is necessary to properly control by family smoking prevention arrangements - substances in alcoholic families, Shall Access, prepare and provide the drug reduced. Keywords Aaddiction - Jail - Addicted – Birjand Addiction , Drugs, Prostitution; Triangular of Destructed Family Parvin Moslemi Bidhendi1, Iraj Esmaili2 1. Azad university Roudehen branch 2. Tehran Prisons HQ Research unit Background and Aim As a sexual perversion, prostitution has always been considered as a threat to society’s health. It exists more or less in all societies. However, its consequences not only involves the own one, i.e. venereal disease such as AIDS, drug addiction, and family disorganization, but also lead to social distortions. This study attempts to explore the role of addiction of women and men in the prostitution. Methods A questionnaire was used to collect data from 206 women who Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S81 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall were arrested on a charge of prostitution and from November 2009 to March 2010 serve their sentence in Raja Shahr, Evin, and Varamin prisons. This is a descriptive-analytic study, so data analyzed by using descriptive and analytic statistics and hypothesis analysis was done by using Pearson correlation coefficient and one sample T-test. Results Findings showed that mean age was 27.3±6.3 years. Marriage statuses among participants were as 34.3% single, 43.1% married, 15.3% divorced and 8.3% widowed. Seventy seven of participants (37.3%) had a history of drug addiction. At the time of arrest 53(25.8%) were addicted. Hypothesis statistical test was shown that a significant correlation between addiction and being prostituted (P=0.001).Prostituted men succeed to make the women to have sexual connection by offering illicit materials and drugs in 71.7% cases. Conclusion Most of this illicit materials and drugs were used by the women, their husband, and other sexual partners. The results were shown that addiction is one of the most important causes of position in women. (p<0.05) Keywords Addiction, Prostitution, Men Genetic Addiction Risk Score, a Methodology to Evaluate Genes that Can Determine Addictive Behavior Hossein Mostafavi1, Esmaeil Shahsavand Ananloo2 1. Department of Physiology and Pharmacology, Zanjan University of Medical Sciences, Zanjan, Iran. 2. Department of Genomic Psychiatry and Behavioral Genomics (DGPBG), Roozbeh Psychiatry Hospital, School of Medicine, Tehran University of Medical Sciences (TUMS), Tehran, Iran. Background and Aim Addiction is a polygenic disorder that can be influenced by environment too. Indeed, genes contributing to addiction may be the main biological differences that make some people comparatively susceptible to addictive behaviors. Genetic-based tests were one approach to determine risk and vulnerability to substance use and also to assess the extent to which genes can determine addictive behaviorin addicted people. Methods By using the “addiction”,“genetic”and “score” as the key words, and searching the PubMed between June 2010 to June 2014, we could find just a few articles. Results Blum et al (2010) were coined the term Genetic Addiction Risk Score (GARS) for probing of polymorphic risk alleles in addicted male people. They assess multiple candidate genes in preference to assess single gene association to forecast future substanceuse. In this method percentage prevalence of risk alleles were cal- culated to give a conventional severity score. Then scores were changed to a fraction and expressed as a Genetic Addiction Risk Score (GARS). Conclusion Scientific knowledge of addiction and the assimilation of these new methods into clinic and most importantly prevention strategies may ultimately lead to improved prevention approachs, better diagnosis and individualized selection of the type of treatment and even it may be used to devise gene therapy in the future. Keywords Addiction, Genetic, Score Addiction rates among the homeless in Tehran, Iran Ehsan Mostafavi1, Fahimeh Bagheri Amiri2, Abbas Sedaghat3, Noushin Fahimfar4 1. Department of Epidemiology, Pasteur Institute of Iran, Tehran, Iran 2. Department of Epidemiology, University of Tehran, Tehran, Iran 3. Center for Disease Control, Ministry of Health and Medical Education, Tehran, Iran 4. Center for Disease Control, Ministry of Health and Medical Education, Tehran, Iran Background and Aim Homeless people are vulnerable and are predisposed to various social and health problems, including drug use and specifically injection drug use. This study was conducted to determine the addiction rates among the homeless in Tehran. Methods In this study, homeless individuals were recruited from five centers that service the homeless in Tehran. A researcher-designed questionnaire was used to study their behavioral patterns. Results 593 homeless people (513 males and 80 females, all Iranian nationals) participated in the study. The median age of the participants was 41 years and the median duration of homelessness was 24 months. 64% of participants had an education level lower than high school and 11.82% were illiterate. 36.08% were using drugs at the time of study. Drug use was more prevalent in women than men (61.53% versus 45.26%) (p=0.02). At last drug use, the most frequent type of drug was methamphetamine (45.53%) and the most common method of using it was smoking (76.95%). There was difference between common type of drug consumed between men (opium: 40.11% and heroin: 44.63%) and women (methamphetamine: 72.50%). 27.45% of individuals with a lifetime history of drug use had injected drugs, and over half of those (52.45%) had shared needles. The median age at first drug injection was 29 years. Men reported injecting drugs more than women (30.02% versus 12.30%) (p=0.003). Conclusion This study showed a high prevalence of drug use among homeless people in Tehran. Drug use differences between men and women were verifiable. Future research should focus on identify- S82 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall ing effective strategies to improve the living conditions and behavior of the homeless. Keywords Homeless, Addiction,Tehran Attenuation of Morphine Induces Physical Dependency, Anxiety and Hippocampus cell Neurodedegeneration with Various Dosage Regimens of Morphine after Precipitated Withdrawal Syndrome in Rat Majid Motaghinejad1, Seyed Morteza Karimian2, Ozra Motaghinejad3, Behnaz Shabab 4 1. Department of Pharmacology, School of Medicine, Iran University of Medical Sciences, Tehran ,Iran 2. Department of Physiology, School of Medicine, Tehran University of Medical Sciences,Tehran ,Iran 3. Department of Pharmacology, School of Medicine, Iran University of Medical Sciences, Tehran ,Iran 4. Solid Dosage Form Department, Iran Hormone Pharmaceuticals Company, Tehran, Iran Background and Aim Long term consumption of morphine produce dependency, anxiety and induces apoptosis, oxidative stress damage of brain cells .In this study, morphine on its own has been used for managing morphine induced dependence , oxidative stress and apoptosis Methods 40 male rats were divided into 5 groups, 4 groups were induced dependency by an increasing manner of doses of morphine for 7 days (15-45 mg/kg). then, the animals received morphine for next14 days by either of the following regimens: 1) once daily 45 mg/kg (positive controls), 2) the same dose at additional intervals (6 hours longer than the previous intervals each time, 3) the same dose at irregular intervals (12, 24, 36 hours), 4) decreasing doses once daily (every time 2.5 mg/kg less than the former dosage). The negative controls received saline solution only. On day 22 all animals received naloxone(3mg/kg) and their Total Withdrawal Index (TWI) and blood cortisol levels were measured. After drug treatment rats hippocampus cell were isolated and their oxidative, anti oxidant ,apoptotic and anti apoptotic factors and also inflammatory parameters were evaluated in isolated hippocampus cell. Results TWI and Cortisol levels were significantly low in all test groups. Also various dosage regimen of morphine in comparison with regular pattern of administration caused decrease in lipid peroxidation and increased the GSH level, superoxide dismutase and glutathione peroxidase activity. Also various dosage regimen of morphine reduced the activity of Bax, caspase-3 , caspase-9 and Tumor necrosis factor alpha and Interleukin 1 beta levels and increased the Bcl-2 activity in isolated hippocampus cell. Conclusion Changing the dosaging regimen of morphine can alter the severity of dependency and also attenuate oxidative stress, apoptosis and inflammation induce by chronic morphine administration. Keywords Morphine, Cortisol, Withdrawal Syndrome, Oxidative Stress, Apoptosis, Inflammation Comparative Effects of Various Doses of Methylphenidate in Anxiety, Depression and Cognition Alteration in Rat Majid Motaghinejad1, Manijeh Motevalian2, Mohammad abdollahi3 1. Department of Pharmacology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran 2. Department of Pharmacology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran 3. Department of Toxicology, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran Background and Aim Methylphenidate (MPH) is a central stimulant that prescribed for the treatment of attention deficit/hyperactivity disorder. But the long-term behavioral consequences of MPH treatment are unknown. In this study, various doses of Methylphenidate were compared in anxiety, depression and cognition alteration Methods Forty adult male rats were divided randomly to 5 groups. Group 1 served as negative control and received normal saline (0.2 ml/ rat), groups 2, 3, 4 and 5 received methylphenidate 2, 5, 10 and 20 mg/kg respectively for 21 days. On day 17, Elevated Plus Maze(EPM), Open Field Test(OFT), Forced Swim Test (FST) and Tail Suspension Test(TST) were used to investigate the level of anxiety and depression in animals. In addition between 17th and 21th days, Morris Water Maze (MWM) was applied to evaluate the effect of methylphenidate on learning and memory. Results Results of our study showed that the animals in MPH-treated groups showed a profound depression in a dose-dependent manner and the period of swimming were shorter in FST at all doses used compared to control group .This study also indicated that animals treated by methylphenidate at all doses studied, had displayed profound anxiety dose-dependently and spent shorter times in open arm of EPM, in comparison to animals in control group. Mean duration of immobility in methylphenidate treated animals were significantly increased dose-dependently compared to animals in control group. The animals in negative control group had more frequency of central square entries and also spent more time in the central region of the OFT compared to groups receiving methylphenidate with doses of 5, 10 and 20 mg/kg (p<0.001). It seems that the animals receiving doses of 5, 10 and 20 mg/kg of methylphenidate has less ambulation distance in comparison to control group. Also methylphenidate at doses of 10 and 20 mg/ kg cause decrease in number of rearing in OFT and this decrease was statistically significant in comparison to control group. Mean of escape latency and traveled distance during four days training in the MWM for the group treated by methylphenidate (20mg/ kg) was higher and this increase was statistically significant compared to control group. The swimming speed was not altered during training trials in any of the animal groups, suggesting that exposure to methylphenidate did not cause any motor disturbance affecting animal performances. Percentage of the presence of Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S83 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall animals in target quarter (quarter in which platform was located during training days) in probe trial session was investigated and results showed that there was a significant decrease in group under treatment by 20mg/kg methylphenidate in comparison to control group Conclusion According to our data we conclude that methylphenidate at different doses cause impairment in memory and learning and increases the anxiety and causes depression in experimental animals and this is far more significant at higher doses. Keywords Methylphenidate, Anxiety, Depression, Cognition The Effectiveness of Individual Counselling on Decreasing Behavior Disorders of Adolescents with a History of Smoking Afrooz Mousavi1, SeyedehAfrooz Mousavi2 1. PhD Student in Sport Psychology of Imamreza University 2. PhD Student in Sport Psychology of Imamreza University Background and Aim Introduction: Most people initiate smoking prior to 18 years of age, with critical periods of experimentation beginning in early adolescence between the ages of 13 and 16 years.The aim of this study was to investigate the effects of Individual counselling based on cognitive-behavioral training on decreasing behavior disorders of smoker Adolescents. Methods In this study 10 smoker Adolescents (10 boys) with behavior disorders which referred to Tehran health home were selected by objective sampling method and were randomly assigned to experimental groups (n=5) and control group(n=5). Experimental group received cognitive-behavioral training 2 sessions a week, lasting 45 to 60 minutes each, over a 8-week period, while the control group received no training at all. Data were collected by Rater behavior disorders questionnaire. Results Significant differences were observed between experimental group and control group. The result indicate that counselling based on cognitive-behavioral training had significant effect on improving anxiety-depression, aggression- hyperactive, anti social behaviors, attention Deficit and adjustment disorder of Adolescents with history of smoking. The Efficacy of N-Acetylcysteine in the Treatment of Methamphetamine Dependence: A Double-blind Controlled, Cross-over Study Seyed Ghafur Mousavi1, Mohammad Reza Sharbafchizadeh2, Mohammad Reza Maracy3 1. Behavioral Sciences Research Center, Department of Psychiatry, Isfahan University of Medical Sciences, Isfahan, Iran 2. Behavioral Sciences Research Center, Department of Psychiatry, Isfahan University of Psychiatry, Isfahan University of Medical Sciences, Isfahan, Iran 3. Department of Epidemiology and Statistics, Faculty of Health, Isfahan University of Medical Sciences, Isfahan, Iran Background and Aim Preclinical studies and early pilot clinical investigations have suggested that N-acetylcysteine (NAC) may be useful in the treatment of the methamphetamine (METH) dependence. This study evaluated the suppressing effect of NAC in METH craving. Methods In a double-blind, controlled cross-over clinical trial, 54 METH-dependent volunteers were chose to receive daily doses of 1200mg of NAC or placebo, randomly. They were intervened in two four weeks sessions. During first session they received either 1200mg/d of METH or placebo. After a three days wash out, the next session started with the cross-over intervention of the previous regimen. Throughout all of this eight weeks, all participants received standardized, Matrix Model of treatment. Craving was assessed using the Cocaine Craving Questionnaire-Brief (CCQBrief).The data were analyzed under SPSS20. Results The mean scores of CCQ-Brief reduced with NAC treatment in both of two sessions of cross-over. There were not any significant difference between two NAC and placebo. Conclusion The NAC showed good efficacy in suppressing METH craving, and may be a useful pharmacological treatment of METH dependence Keywords Methamphetamine, Dependency, Craving, N-acetylcysteine; pharmacotherapy Orexin-A Depresses Inhibitory Synaptic Transmission to the Locus Coeruleus Neurons in Morphine Dependent rats Conclusion Purposeful play is instrumental in reducing children’s stress and generates feelings of effectiveness and wellbeing. Keywords Counseling, Behavior Disorders, Smoking S84 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 Sayed Yousof Mousavi1, Hossein Azizi2, Javad Mirnajafi-Zadeh3, Mohammad Javan4, Saeed Semnanian5 1. Tarbiat Modares University 2. Tarbiat Modares University 3. Tarbiat Modares University 4. Tarbiat Modares University 5. Tarbiat Modares University The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Background and Aim The locus coeruleus (LC) contains large clusters of noradrenergic neurons which project widely throughout the central nervous system and implicated in drug addiction and withdrawal syndrome. The noradrenergic neurons of the LC are under the inhibitory control of GABAergic system which participates in the development of drug dependence. Orexin-A and B are hypothalamic peptides known to modulate arousal, feeding, and reward via orexin receptors (OX1R and OX2R). Orexin neuropeptides excite the noradrenergic LC neurons; however, the effects of orexin neuropeptides on inhibitory synaptic transmission to the LC neurons in morphine dependent rats are unknown. Here, we investigated the effect of orexin-A on spontaneous inhibitory postsynaptic currents (sIPSCs) in morphine treated rat LC neurons. Methods We used whole-cell patch clamp recording in rat horizontal slices containing the LC nucleus. Results Our electrophysiological data indicate that orexin-A (100 nM) application decreased sIPSCs frequency of LC neurons in morphine dependent rats, but did not change sIPSCs amplitude. This effect was blocked by SB-334867, a selective orexin type-1 receptors. Conclusion In this study, our findings suggest that orexin-A depresses sIPSCs frequency through orexin type-1 receptors. It can be deduced that these changes in inhibitory synaptic transmission may be elicited by prestsynaptic rather than presynaptic mechanisms. These results provide in vitro evidence for a critical role of orexin signaling in LC neurons. Keywords Locus Coeruleus; Spontaneous Inhibitory Postsynaptic Currents; Morphine; Orexin-A The Comparing of Spiritual Intelligence and Perceived Social Support in Addicts and Non-addicts in Tabriz Yazdan Movahedi1, Hanya Karazi Notash2, Masoumeh Movahedi3, Reza latifi4 1. Ph.D. Student of Cognitive Neuroscience, Psychology, Psychology and Education, Tabriz, Iran. 2. MSc Clinical Psychology, Tabriz University of Medical Sciences, Tabriz, Iran. 3. MA of Family Counseling, Lorestan University of Medical Sciences, Korramabad, Iran 4. MA Clinical Psychology, Psychology and Education, Tabriz, Iran. Background and Aim This study compares the spiritual intelligence and social support in addicts and normal people. Methods In this research, 50 addiction and 50 people from their normal counterparts by making available in the Tabriz of were selected randomly questionnaire data with the help of spiritual intelligence and demographic characteristics and social support were collect- ed. These data were analyzed using SPSS 20 software. For data analysis and multivariate analysis (MANOVA) was used. Results The results showed that the components of spiritual intelligence and perceived social support, there is significant difference between addicts and normal subjects. Conclusion The results showed that addiction of spiritual intelligence and social support has lower than normal people. Keywords Spiritual Intelligence, Perceived Social Support, Addiction Comparing Emotion Regulation in Methamphetamine Abusers with and without Risky Behavior Mohammad Najafi 1, Ali Farhoudian 2, Marziye AlivandiVafa3, Hamed Ekhtiari4, Omid Massah5 1. M.Sc. of Clinical Psychology, Islamic Azad University, East Azerbaijan Research and Sciences Branch, Tabriz, Iran 2. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 3. Ph.D. of Psychology, Associate Professor of Psychology Department,East Azarbaijan Science and Research Branch, Islamic Azad University,Tabriz,Iran 4. Physician, Academic Member & Manager of Translational Neuroscience Program of Institute of Cognitive Sciences Studies, Tehran, Iran 5. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran Background and Aim People may deny stress to get rid of it.In this case, they tend to exhibit high-risk behaviors. Inability to solve problems and emotional conflicts leads to high-risk behavior in addicts. This study was designed to investigate the relationship between risky behavior history (prison records and drug injection history) and emotion regulation in methamphetamine abusers Methods In this case-control study, 60 methamphetamine users (13 people with prisons records and 11 people with drug injection history) were selected purposefully frompersons who had been admitted to convenient treatment centers (MMT center, addiction treatment camp and self-help groups and Narcotics Anonymous). Demographic data and risky behavior history were gathered. The ‘Cognitive Emotion Regulation Questionnaire’ (CERQ) was used to assess emotion regulation. Data were analyzed using multivariate analysis of variance (MANOVA). Results The findings revealed no significant difference in CERQ subscales between the groups. Conclusion There was no significant relationship between emotion regulation and risky behavior such as prison records and drug injection history in methamphetamine users. Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S85 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Keywords Emotion Regulation , Risky Behavior , Methamphetamine , Prison , Drug injection “Female Drug users in Labor Market: They Do Not Respond to Expectations” Parisa Nakhaei1, Jaleh Shaditalab2, Molouk Azizzadeh3, Sonia Ghaffari4 1. UNODC 2. Tehran University 3. UNODC 4. UNODC Background and Aim Social reintegration is part of aftercare phase and the focus is on training, education, development of skills, employment and housing. The opportunities to learn employment skills, promoting income-generating projects and providing transitional housing are the most important factors in the lives of women drug users. The aim of the present article is to report primary findings of a qualitative study on the experiences of FDUs (Female Drug Users) and Employers in labor market and try to discuss the challenges and why FDUs are not responding to the expectations of employers. Methods Since there are no research and study in Iran about this objective, qualitative methods such as an exploratory study was selected. In order to acquire a whole perspective and to response some important questions in this field, a semi–structured interview technique was used for data collection. The interviewees were chosen from three different groups which their points of view regarding to the women’s employment situation were influential: • Women drug users who had the experience of employment (30 interviews) • Service providers (14 interviews) • Employers who had accepted to employ treated women drug users (8 interviews) The interviews were continued until reaching data to saturation point. Results The most important findings of the study are expectations and challenges which the mentioned groups supposed. • In the perspective of women drug users, the most important difficulties were housing, physical health, low incomes, initial capital to start a personal employment, difficulties in finding an appropriate job, and abuse by employers and other employees. • In the service providers’ point of views, housing, mental and physical health, income and employment, and abuse and inappropriate behaviors in work places were the most overwhelming challenges. • The most outstanding problems that were stated by the employers regarding to the drug users employees were lack of timeliness, regularity, respecting the hierarchy, and being trusty of women. The women drug users were also considered as a risk for other employees. Another problem caused by them was regarding their unsuitable dressing. Conclusion Due to the lack of a given plan in order to help the women to join labor market and based on some similarities between women drug users’ employment in Iran and other countries, it has to be mentioned that applying the experiences of other countries in each process of their employments such as preparing the women for the job, providing practical help to them for finding a job, and sufficient help after finding the job and for keeping it, is necessary. All in all, based on our challenges in Iran and regarding the lessons learnt from other countries, paying attention to some pivotal points is inevitably undeniable. Some of these points are flexibility in providing services by service centers, supporting the families and children of the women by peers or institutes, paying attention to some of their mental problems regarding their permanent jobs, teaching them soft skills, providing access to micro-finance, trying to woo supports of trustworthy and local employers, and to provide the women with vocational training based on their interests Keywords Female Drug Users-Labor Market- Employers- Service Providers- Challenges Characteristics of Drug Demand Reduction Structures in Britain and Iran Hooman Narenjiha1, Hassan Rafiee2, Roya Noori3, Hamid-Reza Khoddami-Vishteh4 1. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 2. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 3. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 4. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran Background and Aim Researchers, policymakers, and administrators at both national and international levels have neglected the study administrative structures of drug demand reduction (DDR). By studying these structures in the UK and Iran, one can shed light on peculiarities of and shared challenges for policymakers. Methods In this study, experts from the addictive behavior department of St George’s University (London) and a group of Iranian experts in the field of DDR met and exchanged ideas and knowledge about the organization of DDR. Then, via teamwork, they drew connections between the organizations involved in the implementation process and compared the two charts in order to assess the potentialities and liabilities of policies Results Overall, seventeen characteristics for the establishment of an efficient implementation structure were agreed. These, inter alia, included: multi-institutional framework; inter-institutional collaboration; compartmental distribution of inter-institutional activities; to share experiences; community-based activity; bi-lateral relationships; feedback systems; to collect data rapidly; grassroots community roots; flexibility at the local and regional levels; solid connections with research centers; up-to-date policymaking; empowering the local; and seeking maximum benefits with minimum resources. Conclusion By elucidating the impact that these measures could bring about, this research aims at providing a frame for action to policymakers, S86 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall stakeholders and personnel active in DDR. The frame of analysis casts light on the Iranian case, while providing comparative intuitions for other experiences of drug policy. Recognizing these characteristics as essential steps of an evidence-based policy could help policymakers to improving the effectiveness of policy and bring about effective management of the widespread use of psychoactive substances. Keywords DDR: Drug Demand Reduction. Characteristics.structure. policy makers. Comparison of Efficacy Based on Acceptance and Commitment Therapy (ACT) and Cognitive Behavioral Therapy (CBT) on Craving in Amphetamine-Dependent Individuals Rebwar nazari1 1. MA in General Psychology Allameh Tabatabai University, Ghoghnous Substance Abuse Treatment Center Neda Nikrah1, Bahman Bahmani2, Mahmood Tavakoli3, Ali Farhoudian4 1. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 2. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 3. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 4. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran Background and Aim The aim of this study is to examine the effectiveness of social problem-solving education program on increase of resiliency of the mothers have addicted offspring. Addiction to drugs is considered to be an Chronic disease.. Vulnerability towards using drug abuse and tendency to drugs are affected by combinations of environmental and hereditary. Methods Background and Aim The Third Wave Therapy treatments rather than challenge the knowledge, awareness and acceptance of people’s emotions and cognitions and behaviors are emphasized. The approach of cognitive behavioral therapy is believed that cognitions and beliefs inefficient to have emotional and behavioral modification to be corrected. The present study compared the efficacy of acceptance and commitment therapy based on cognitive behavioral therapy was the craving for amphetamine dependence. Methods This clinical trial with two groups receiving intervention based on acceptance and commitment, and cognitive - behavioral and control along a track (three months) is. The population study of patients admitted to an addiction treatment center in Tehran Phoenix that are related to amphetamines, form. Our sample included 36 patients dependent amphetamine addiction after performing index (ASI), amphetamine -dependent patients were diagnosed. The research method was an experimental design with pretestposttest and control group. The samples are 40 mothers have addicted offspring whom selected by random sampling in tow experimental group (20 mothers) and control (20 mothers) group. For experimental group but not for control group, the 10 sessions of 90 minute Social Problem-Solving Education were did. The research tool was scale of Conner and Davidson resiliency (CDRISC). The lowest resilience score in this standard was zero and the highest was 100 and this scale was standardized by M, Mohammedi in Iran. The data was analyzed by single-variable ANOVA. Results The result of post test showed significant difference statistical on resiliency variable between experiential and control group in resiliency enhancement at periods of post test and follow up. P>0/01 Conclusion Results The results of the ANOVA showed a reduction in craving posttest scores of both groups was significant. Tukey test results indicate that both methods are effective in reducing craving patients. Comparison with the control group, each of the two methods indicates that the scores are based on acceptance and commitment therapy and cognitive behavioral had a greater increase. The result of the study showed that social problem-solving education, increase of resiliency of the mothers have addicted offspring and been effective. social problem-solving education can effective in resolving other problems and we offer that it must section of hygiene ministry’s prediction at the side of other trainings. Keywords Resiliency- problem-solving- Addiction. Conclusion The study indicates acceptance and commitment therapy and cognitive behavioral therapy are both based on the reduction of craving in amphetamine -dependent individuals are effective. Keywords Effectiveness of Social Problem-Solving Education Program on Increase of Resiliency of The Mothers Have Addicted Offspring Acceptance and Commitment Therapy, Cognitive Behavioral Therapy, Craving, Amphetamine Examining Social Factors Affecting Women Tend to Drug Addiction on the City in Kerman 93 Years Samane Niktabe1, Reza Abbasi2, Syed Habib Ullah Hashmi3 1. Young Researchers and Elite Club, Baft Branch, Islamic Azad University, Baft, Iran. PhD Student in Sociology Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S87 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall 2. Director General of Kerman Welfare Department. Doctor 3. Dean of Applied Science and Welfare Background and Aim The study of social factors affecting women tend to drug addiction on the city of Kerman 93 in years. The research assumptions, including the disintegration of domestic abuse, family members, economic and social base through the theoretical perspectives learning Sutherland, social theory herechi reviewed Methods The present study methods survey data and via and sampling method available to the volume of the sample 350 reviewed. collecting information with the use of the technique of descriptive statistics inference and cholera software spss statistical analysis. Results According to the results of the results in Table found between the rupture of the family and the tendency of women to drug addiction to 19 % at the level of significant 01/0 meaningful relationships. between the abuse of family members and a tendency to drug addiction to 36 % at the level of significant 01/0 meaningful relationships. between the base of the economic and social tendency to drug addiction to 196 % at the level of significant 01/0 meaningful relationships. Conclusion Women half of the population of our society, and all of the international community, the fact is, in fact, the statistical and in practice, so that it should be in all areas of social life is not extended, because despite the existence of the official admitted to the presence of women in all areas of social, economic and cultural and political rights, in all fields and have been ignored. Based on the findings it was clear that the rupture between domestic abuse, family members, economic and social base meaningful relationships. However, a few studies have been conducted on stimulant use in the region including Iran Methods The current cross-sectional survey was conducted in 2010 to determine the prevalence of stimulant use in the general population of Tehran, Iran. 5,956 participants were recruited from 22 areas of Tehran. Participants were interviewed on details of demographics and lifetime drug use by a researcher-designed questionnaire. Results More than 90% of participants were men. Participants were in the age range of 16-60 years. The mean age of the sample was 32 (SD=11) years old. More than half of the participants reported a high school education. 4.2% of participants reported lifetime stimulant use. Interestingly, 2.5% reported lifetime use of opiates. Ecstasy, methamphetamine, Ritalin tablets, and cocaine were the prevalent stimulants of used among the sample. The mean age of stimulant users was significantly lower than opiate users (29±10 vs. 36±11 years, p < 0.001). Stimulant users were more likely to be single compared with opiate users (79% vs. 43%, p < 0.001). The previous history of drug treatment was significantly higher among stimulant users than opiate users (52% vs. 20%, p < 0.001). Conclusion The study findings showed that compared with opiate users, stimulant users were younger, more likely to be single and have a history of drug treatment. Stimulant use has important health and treatment implications and should be specifically considered for treatment. Preventive measures and stimulant education are discussed. Keywords Amphetamine, Stimulant, Opiate, Iran, Persian Gulf Investigation of Students’ Needs Assessment Towards Crack Abuse Side Effects Keywords Social Factors, Tendency to Addiction, Border City, Drugs Maryam Nooritajer1 1. Islamic Azad University, Islamshahr Branch Stimulant use Problem in Iran: the First Report form the Persian Gulf Region Roya Noori1, Zahra Alam mehrjerdi2, Abbas deilamizade 3, Kate Dolan4, Hooman Naranjiha5, Hassan Rafiey6 1. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 2. Program of International Research and Training, National Drug and Alcohol Research Centre, Faculty of Public Health & Community Medicine, University of New South Wales, Sydney, Australia 3. Rebirth Society (NGO), Tehran, Iran 4. Program of International Research and Training, National Drug and Alcohol Research Centre, Faculty of Public Health & Community Medicine, University of New South Wales, Sydney, Australia 5. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 6. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran Background and Aim Stimulant use is a new health concern in the Persian Gulf region. Background and Aim Regarding the increasing rate of crack abuse in Iran and also regarding that 25% of Iranian drug abusers (90% of which are under 24 yrs. old) use this substance, the necessity for interventions by various social groups, esp. students, in the area of educating the population at risk for substance abuse is increasingly needed; and as the first step in formulating an educational program is determining students’ needs assessment, the most effective approach for determining an appropriate educational content is need-analysis. The present research was aimed at determining students’ needs assessment towards crack abuse side effects in Islamic Azad University, Islamshahr Branch. Methods The present descriptive and analytical research investigated stu- S88 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall dents’ needs assessment towards crack abuse side effects at three levels, namely their knowledge, attitude, and performance. Therefore a student needs education if he/she scores 50% or less in each area. The research population (n = 906) consisted of all the students of different faculties of Islamic Azad University, Islamshahr Branch and were selected using the stratified sampling method and were allocated to respective groups according to gender. The data collection tool was a questionnaire. The research data were analyzed using the t-test, and also Chi-square and ANOVA tests and the Pierson correlation coefficient. Results The results obtained regarding students’ needs assessment towards crack abuse side effects at three levels, namely their knowledge, attitude, and performance revealed: (1) The mean short-term and long-term knowledge’s were 36.77 and 40.48, respectively, which showed a statistically significant correlation (p ? 0.000; t = 5.13; df = 905). (2) A statistically significant correlation was also revealed between the mean short-term (73.57) and long-term (64.19) attitude (p ? 0.000; t = 17.35; df = 892). (3) Statistically significant correlations were also revealed between crack abuse side effects and gender, the faculty and educational level, parents’ educational level, smoking type and duration, having friends or family members with substance abuse or performing doping, and the number of family members (p ? 0.000 in all cases). Conclusion The results of the present research regarding students’ needs assessment towards short-term and long-term crack abuse side effects revealed that short-term knowledge trends toward low-level as compared to long-term knowledge; students’ long-term attitude towards crack abuse side effects trends towards negative; and students’ long-term performance trends towards unfavorable. Generally, students’ needs assessment towards short-term and longterm crack abuse side effects was at the high level, but rendering needs assessment towards short-term crack abuse side effects had a higher priority, i.e. their needs assessment is primarily based on short-term; suggestions are also provided regarding the application of the research findings. Keywords Needs Assessment, Crack Abuse, Side Effects, Knowledge, Attitude, Performance. The Comparison Schema Domains in Criminal and Normal Individuals Manije Noshirvani1, Tahere Hasib Hosinabadi2, Monire Eslami Mehdiabadi3 1. M.A. Clinical Psychology .Kharazmi Univercity, Tehran, Iran 2. M.A. Educational Psychology .Tehran Univercity.Tehran, Iran 3. Bachelor of Councelling. Azad univercity. Ashkezar,Yazd Background and Aim Young believe that early maladaptive schemas are often underlying characteristics of most mental health disorders, particularly disorders that are chronic and resistant to change, such as substance abuse .The purpose of this study was to compare schema domains in criminal and normal individuals in YAZD Methods The research method was a causal- comparative approach. The subjects were divided into two groups of 327 (one group of criminal and one group of normal individuals).They were selected randomly among the prisoners of steal, financial and narcotic Drugs crimes from Yazd, Ardakan and Tabs prisons. Two groups were match in age, education, marital status and job. The data were collected by Young Schema Questionnaire- Short Form(YSQ-SF) (Young,1998) and were analyzed t-test student for independent groups. Results The findings indicated that there was significant difference between Schema domains of criminal and normal individuals in: Disconnection and Rejection domains, Impaired Autonomy and performance, Impaired Limits ,Other-Directedness and Over vigilance/inhibition . Conclusion High scores in most of the schema domains could lead to the tendency to commit steal, financial and narcotic Drugs crimes .this results show that in cases of prevention of crimes and in treatment more attention must be given to cognitive factors. Keywords Schema Domains, Criminal, Normal Individuals The Effect of Addiction on Quality of Family s Life Mehrdad Nourzadeh1, Mahmud Baratvand2 1. Head of Health Department of Khuzestan Prisons 2. Head of Research Department of Khuzestan Prisons Background and Aim Addiction has a destructive effect on the structure of family and its members. The effects can be observed and assessed in educational ،fiscal، the members communication and so on. Based on the previous studies، it can be expected that addiction leads to unqualification of family ، however the effect can be modified by social class and level of income Methods Data was gathered from self_referred clients to therapeutic centers of ahvaz in 2012. the Statistical community was all clients to self_ reffered centers for cure addiction ، among them 115 people were selected randomly. Research design was post or causal and the data was collected by applying 2 man_ made questionnaire of life quality and demographic Results indicated the reduction life quality in family. Maximum of reduced was seen in low_income families . There was also a significant relationship between family size and reduction in family qualification. Conclusion in spite of constructive effects of addiction on family there are Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S89 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall some moderator factors which can help the families. These factor contain the addiction durance،age، family size and other demographic factors. Keywords Addiction-Contructive- Indicated Role of Motivations Behavior Change in Continuation of Treatment Individuals Relevant to Drug Ameneh Oji1, Faramarz Sohrabi2, Farhad Jomehri3, Omid Yahya zade4 1. Ameneh Oji 2. Faramarz Sohrabi 3. Farhad Jomehri 4. Omid Yahya Zade Background and Aim Role of motivations behavior change in continuation of treatment individuals relevant to drug Methods Procedure: This research is a descriptive analytical research which is regarding patrons to congress 60 Tehran city, from Farvardin 1392(April 2013) to Tir 1392(July 2013). Studied samples were individuals who for the first time patrons for treatment and in first patrons, before beginning treatment had completed mentioned questionnaire. Patrons who were under treatment due to likeliness of any change in primary reasons and motivation of drug treatment, were not samples of this research. Tools of collecting information, was questionnaire of readiness stages for change and willing for treatment of addiction. Thus from 140 number individuals who had trend to complete questionnaire, after obtaining satisfaction letter, were part of research samples. These individuals all had background of addiction to at least one of drugs and voluntarily were patrons. And completed questionnaire in two parts. Obtained information were collected in designed forms and by software SPSS21 were analyzed. Results Results From 140 individuals who participated in test 66 individuals had remaining in treatment and 74 individuals had not remaining and exited from treatment Conclusion Results showed, individuals who remained in treatment in recognition had received higher scores thus first assumption based on difference in model of recognition among individuals who had remaining in treatment and those who had not remaining, was significant and was confirmed. Also second assumption among individuals who had remaining in treatment and those who had not remaining in dualism had difference. Score of individuals who had not remaining in treatment in dualism are more so second assumption also was confirmed. Thus third assumption among individuals who had remaining in treatment and those who had not remaining in performed actions there are differences. Scores of individuals who were remained in treatment were higher than those who had not remaining. Third assumption also was confirmed. Important point in treatment of addiction is that consum- ing individuals of drug many times had acted for treatment but again went to consuming drug and this complex process may be repeated many times, but difference of these repetitions is time of returning(recurrence) again to drug consumption, and time length of cleaning (non-consumption drugs). Keywords Motivations Behavior Treatment Drug Relevant In Vivo Effect of Methamphetamine on Thioredoxin Reductase Activity in liver and Brain of Methamphetamine Received rats Hassan Ostadi1, Mohammad Hossein Tanipour2, Alireza Hosseinzade3, Faezeh Sadrabadi Haghighi4, Zahra Sharghi Shahri5, Seyed Isaac Hashemy6, Mohammad Soukhtanloo7 1. Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran 2. Department of Medical Biochemistry, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran 3. Department of Biology, Faculty of science, Science and research branch of Islamic Azad University Kurdistan, Iran 4. Department of Medical Biochemistry, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran 5. Department of Medical Biochemistry, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran 6. Department of Medical Biochemistry, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran 7. Department of Medical Biochemistry, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran Background and Aim In these days the abuse of synthetic drugs such as Amphetamine family (as known the “Glass”) is prevalent. These industrial drugs affect many features of biochemical parameters and lead to different abnormality in body normal functions. Methamphetamine is a highly addictive drug with potent central nervous system stimulant properties. The stimulant effects of methamphetamine can last from seven to 24 hours. The thioredoxin system is composed of thioredoxin reductase (TrxR) and thioredoxin. TrxRs are a family of selenium – containing pyridine nucleotide-desulfide oxydoreduses. Thioredoxin reductase transfers electrons from NADPH to thioredoxin, which in turn reduces thioredoxin peroxidase and other important redox proteins. Methods The “glass” was obtained from Khorasan Razavi Drug Control Coordinating council. First step for detecting effects of Methamphetamine on mammalian Thioredoxin reductase activity was injection of Meth to rats. There were 5 different dosses and 3 different period of exposure time. Each group received one of these dosses from 2.5mg/kg to 10mg/kg. Rats were killed after 3, 14 or 40 days. The tissues were disparted and analyzed based on the reduction of DTNB with NADPH to TNB. Results Thioredoxin reductase activity was examined in liver and brain tissues. In brain tissue at chronic group (40 days) Thioredoxin reductase activity was increased significantly in compare with control groups. Although, we didn’t find any distinctive results in other groups (Acute and sub-acute). In liver tissue Thioredoxin reductase activity did not increase between time periods and also different doses in compare with control groups. S90 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Conclusion The “Glass” (the street name for methamphetamine) is a synthetic drug that damage many features of the human’s health. It was proved that Methamphetamine disrupts the oxidant – anti oxidant balance in favor of oxidant. Thioredoxin reductase has important role on maintenance this balance. This study emphasized that Thioredoxin reductase activity significantly raised in longest exposure in rat’s brain. This raising is dose - dependent in chronic group in compare with control group. Unlike brain results, in liver tissue Thioredoxin reductase activity didn’t show any change after treat by Methamphetamine. We suggest using of more samples and various doses in next studies to obtain more confident results. Keywords Methamphetamin, Thioredoxin Reductase, Oxidative Stress Gene Expression of Protein Kinase Cγ in the Spinal Cord was Decreased During 8 Days of Induction of Morphine Analgesic Tolerance in rat Neda Parvini1, Shamseddin Ahmadi2, Jalal Rostamzadeh3 1. Department of Biological Science and Biotechnology, Faculty of Science, University of Kurdistan, Sanandaj, Iran 2. Department of Biological Science and Biotechnology, Faculty of Science, University of Kurdistan, Sanandaj, Iran 3. Department of Biological Science and Biotechnology, Faculty of Science, University of Kurdistan, Sanandaj, Iran Background and Aim Morphine is a widely used opioid analgesic but induction of morphine tolerance after its repeated injections has limited the use of the drug. Morphine binds selectively to the µ opioid receptors, which in turn activate protein kinase C (PKC) in its signaling pathway. PKC, especially its gamma isoform(PKCγ), is considered to play a key role in the development of morphine tolerance. The present study was performed to investigate the possible changes in gene expression of PKCγ in different times during induction of morphine tolerance in rat spinal cord. In can be concluded that expression of PKCγ during induction of morphine analgesic tolerance from day 1 until day 8 has been decreased and this decrease may account, at least partly, for its ineffectiveness or morphine-induced analgesic tolerance. Keywords Protein kinase C, Gene Expression, Analgesic Tolerance Effect of Training on Stress Management Techniques to Reduction of the Ability of Adaptation in People with Drug-Dependent Malihe Pashib1, Sara Abdolvahaby2, Zahra Hematy Javanmard3 1. MA in Clinical Psychology Torbat Heydariyeh University of Medical Sciences , Torbat Heydariyeh,Iran 2. MA in Clinical Psychology Birjand University 3. MA in Clinical Psychology Birjand University Background and Aim Objectives: There are numerous factors which play the key rolls in emerging and continuing addiction. One of these factors, is, few skills to deal with stress, caused by problems and troubles in life and also the reduction of the ability of adaptation and positive, effective behaviors. Training programs in these aspects develop and improve the psycho- social capabilities and accepting the responsibilities of the social rolls. The independent variable of the present study is 8 session treatment to deal with stress performed as a group for the experiment group and the dependent variable which is the score each subject is acquired in Inventory. Methods The statistical community of this study ismale drug addicts living in Mashhad. Subjects were selected randomly and then classified at random into two groups of 15 people of experiment and control groups. In this study, semi-experimental research method and pretest-posttest design with control group was used and data have been analyzed through SPSS software and T test. Results Methods We used male Wistar rats in experiments. Two experimental groups received morphine (10 mg/kg, i.p.) or saline (1 ml/kg, i.p.) twice a day for 7 days and induction of morphine analgesic tolerance was assessed with a hotplate test during the schedule on days 1, 4 and 8 (one day after the last injection). For gene expression study, we used a semi-quantitative RT-PCR method to measure changes in gene expression of PKCγ at mRNA levels in other experimental groups including control and morphine-treated groups on days 4 and 8 after the injections. Results Conclusion Expression of PKC? in morphine-treated group compared to the saline-treated control group on days 4 and 8 after injection was not significantly altered. However, expression of PKC? in morphine-treated group on day 8 of the schedule compared to its expression in the group with day 4 morphine treatment was significantly decreased. The results of the study showed that stress treatment has been effective in reduction of the ability of adaptation of drug users. Therefore, the training program of how to deal with stress plays a main role in reducing drug-addicted users decided to quit and thus help them quit more successful in a longer period of time. Conclusion The results of the study showed that stress treatment has been effective in reduction of the ability of adaptation of drug users. Therefore, the training program of how to deal with stress plays a main role in reducing drug-addicted users decided to quit and thus help them quit more successful in a longer period of time. Keywords Training to Deal with Stress, Adaptation, Drug-Dependent Individuals Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S91 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall The Prevalence of Ever once Substance Abuse Among Yazd Pre-University Students, During 2012 Azar Pirdehghan1 1. Assistant Proffessor in Community and Preventive Medicine Department , Medical School, Hamadan University of Medical Sciences, Hamadan, Iran Background and Aim Substance abuse is one of the main health problems in the world and Iran and awareness about it’s prevalence in the society, particularly the susceptible society of students, is very important with regard to the population pyramid of Iran. The aim of present study was assessing the prevalence of ever once substance abuse among Yazd pre-university students, during 2013. Methods This study was performed by cross-sectional method. The sampling size was 704 Yazd students in pre-university grade by a multistage cluster sampling. Our research instrument was the self-administrated questionnaire adapted from the questionnaire of substance abuse supervised by specialists in social medicine. The questionnaire consisted of two parts; sociodemographic information and questions about the use of 40 different drugs, in which the case of experiencing their use for ever once and also the age of the first experience was asked. The collected data was analyzed using SPSS. Results Of total 704 students, the experience of ever once substance abuse was 51.4% (58% in boys & 39.8% in girls).The most common substance abuse in the students, respectively, were: hookah 41.3%, cigarette 17.5%, alcohol 10.8%, morphin 6.4%, anabolic steroids 5.4%, diazepam 3.6%, diphenoxylate 2.8%, opium 2.7%, tramadol 2.7%, alprazolam 1.8%, snus 1.3%, oxazepam 1.3% & methylphenidate 1.3%.Those frequencies In girls, were: hookah 28.1%, cigarette 9.8%, morphin 8.2%, diazepam 5.5%, alcohol 4.3%, opium 3.1%, diphenoxylate 2.7%, anabolic steroids 2.3%, chlordiazepoxide 2.3%, alprazolam 2%, oxazepam 2%, lorazepam 2% , clonazepam 1.6%, & methylphenidate 1.2% ;And in boyes: hookah 48.9%, cigarette 21.9%, alcohol 14.5%, anabolic steroids 7.1%, morphin 5.4%, tramadol 3.8%, diphenoxylate 2.9%, opium 2.5%, diazepam 2.5%, snus 2%, alprazolam 1.8%, bhang 1.8% & methylphenidate 1.3%,respectively.The first age of experiencing the drugs was 14.9 years & friends were the most important person for accessing to drugs to students. Independent Prognostic factors for substance abuse were: male, older age, having a history of failure in education, last child of the family & master’s degree or higher for the student’s father that these factors increased the risks of substance abuse to 1.7, 1.4, 1.6, 1.6 and 3.6 respectively. Conclusion Present study showed that substance and drug abuse in Yazd adolescents are prevalent. Given up the mean first age of experiencing the drugs was too low, It is recommended that substance abuse prevention programs might be helpful in the middle school and first grade high school. Also the most important aim groups for intervention in future plans might be male students, older age, last child of the family, studying in the non-profit schools, mathematical discipline, having a history of failure in education and/or higher education for student’s father. Keywords Substance Abuse, Drugs, Student, Pre-university, Yazd, Iran. The Concept of Phenomics in Addiction Alireza Pirkhaefi1, Esmaeil Shahsavand Ananloo2 1. Department of Clinical and General Psychology. School of Psychology. Islamic Azad University Garmsar Barnch.Garmsar.Iran 2. Head. Department of Genomic Psychiatry and Behavioral Genomics (DGPBG), Roozbeh Hospital, School of Medicine, Tehran University of Medical Sciences (TUMS), Tehran, I.R. Background and Aim The evaluation of the complex traits such as addiction, just based on the clinical phenotypes (syndromes and symptoms) is a very superficial evaluation, and is neither valid, nor reliable. Phenomics in psychopathology is a new concept that systematically studies and evaluates the complex phenomena in a multi levels approach. In this regard, addiction has to be evaluated systematically based on a multi levels approach, including cognitive, emotional, molecular, genomics, epigenomics, and … levels. Methods By using the “phenomics”, “addiction”, and “psychopathology” as key words, and searching the PubMed database between June 2009 to June 2014, we could find just a few articles. Results Phenomics in addiction disorders evaluate their presentations in levels of clinical (e.g., syndromes, and symptoms), cognitive, neuronal (e.g., neuronal networks, neuronal synapses), signaling pathways, molecular (e.g., proteins), genetic and epigenetic levels. Conclusion Researches in the fields of genomic psychiatry and behavioral genomics hope that the phenomics approach to the complex mental traits and disorders (e.g., addiction) will make the diagnosis, assessment and treatment of these group of traits and disorders more accurately and also reliably Keywords Phenomics, Psychopathology, Addiction Evaluation of the Clinical Effects of Acupuncture in the Treatment of Drug Addiction Eisa Pirmoradi1, Ali Pirmoradi2, Maryam Pourabdollahi3 1. Research Insitute for Islamic Complementory of Medicine ,Iran University of Medical Sciences , Tehran , Iran 2. Sharif university 3. Islamic Azad university Background and Aim To investigate the effect of acupuncture on the treatment of drug S92 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall abuse, 150 patients referred to a private addiction treatment center in the city of Kerman, Iran were selected. Half of the participants were randomly assigned to the experimental condition receiving acupuncture and another half’ to the control condition receiving drug therapy. The main criterion for participant grouping was the type of the drug used. Following the detoxification phase, a morphine and methamphetamine tests were conducted on the participants. Moreover, all participants were referred to a psychologist to receive psychological treatment. Results indicated that compared to the patients under drug therapy, those receiving acupuncture had a higher rate of addiction symptoms alleviation Sciences, Kerman, Iran 4. Center for Disease Control, Ministry of Health and Medical Education, Tehran, Iran 5. Center for Disease Control, Ministry of Health and Medical Education, Tehran, Iran 6. Center for Disease Control, Ministry of Health and Medical Education, Tehran, Iran 7. Regional Knowledge Hub, and WHO Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran. 8. Regional Knowledge Hub, and WHO Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran. 9. MSc student of social research, AL-Zahra University, Tehran, Iran Background and Aim Methods 150 patients (heroin ,opium and methamphethamine addicts) who were referred to the Milad drug abuse treatment center in the city of Kerman, were randomly assigned into experimental and control groups each containing 75 patients. The experimental and control groups were treated by acupuncture and drug therapy (methadone or clonidine along with other supplementary drugs such as tranquilizers) respectively. All the subjects were matched in terms of the socio-economic and age factors. Results In this study, the treatment results for acupuncture and drug therapy that were applied to the patients suffering from drug abuse (opium , heroin and amphetamine) were compared and the level of improvement, until the end of the detoxification period, 6 months and 1 year following this period, were evaluated. The findings revealed that acupuncture is more effective than drug therapy. So, 1 year after the detoxification period, the acupuncture patients improved 2 times than the drug therapy patients. Conclusion Based on the findings derived from the present study, as well as other research investigating the effects of acupuncture on drug abuse treatment, it can be concluded that this treatment method can be used as an effective intervention across all the drug abuse treatment clinics. However, it should be noted that the physicians experience, knowledge and skill could have a very considerable role in the process. Keywords Excessive alcohol consumption and stimulant drugs use have been positively associated with several psychological sequels such as reduced cognitive capacity, behavioural problems, and impaired decision-making, and impulsive personality traits. A substantial body of research indicates that the consumption of alcohol/stimulant drugs can enhance the allure of engaging in sexual contacts while decreasing the individuals’ inhibition and ability to judge the possible negative outcomes their risky sexual behaviour. Therefore, alcohol has been reported as a major risk factor for sexually transmitted diseases such as AIDS. This study tries to assess the prevalence of alcohol and stimulant drug use and risky sexual behaviours among the 19- to 29-year old age group in Iran Methods This national cross-sectional survey was conducted on multistage stratified cluster sample of 3246 participants (aged 19-29) in 13 provinces. Using a standardized pretested structured questionnaire, data was collected on participants’ history of alcohol and stimulant drugs consumption, condom use, and risky sexual behaviours Results Based on our findings, 19.5% of the participants had ever had extramarital sex (31.7% of men and 9.6% of women), of which, 39.9% had consumed alcohol and stimulant drugs before their sexual contact. Only 21.7% 0f those with a history of extramarital sex reported constant condom use in their extramarital sexual intercourses Conclusion Acupuncture , Drug addiction , Psychological Treatment Drug and Alcohol Consumption and Sexual Risk Behaviour among 19- to 29-Year-old Group: Findings of a National Survey in Iran Hamid Sharifi1, Ali ahmad Rafei rad2, Ali Akbar Haghdoost3, Abbas Sedaghat4, Maryam Sargolzaei Moghadam5, Mohammad Mehdi Gouya6, Mohammad Karamouzian7, Samira Hosseini Hooshyar8, Marzieh Mohammadi9 1. Regional Knowledge Hub, and WHO Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran 2. Ph.D. student of cultural sociology, Allameh Tabatabaei University, Tehran, Iran &Regional Knowledge Hub, and WHO Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran 3. Regional Knowledge Hub, and WHO Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical This study shows that a considerable proportion of Iranian 1929-year old group had consumed alcohol and/or stimulant drugs before engaging in extramarital sexual intercourse. Prevention and control programmes should design and implement appropriate interventions targeting this critical age group in particular Keywords Alcohol, Stimulant Drugs, Extra marital sex, Condom, Iran. Evaluation of Drug Addiction in Women in Substance Abuse Control Centers in North East of Iran Mohamad R Mohamdi 1, Reza Barzegari 2, Tina Bagheri 3, Soheil Rafiee 4 1. Specialist Neurosurgeon , Medical Faulty, Golestan University of Medical Sciences, Gorgan , Iran 2. MD , Golestan University of Medical Sciences, Gorgan, Iran Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S93 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall 3. MS Clinical Psychology, Golestan University of Medical Sciences, Gorgan, Iran 4. MD MPH , Infetility Research Center , Golestan University of Medical Sciences, Gorgan, Iran Background and Aim Women’s role as a consumer or as a person who is facing with risks is so important in studies of substance abuse. However, major studies on this field aimed at studying on male population. Therefore, the aim of this study described the pattern of using illegal drugs among women belong to substance abuse control centers of north east of Iran ( Golestan Province ). Methods This cross sectional study as a census was done on all authorized substance abuse treatment centers in golestan province in 2014 . Information about demographic data, types of drugs, method of using, duration of addiction and onset age was extracted from the files of self-referred women. Results There were 1143 women in Golestan area abuse treatment centers who were 7.9 % of all registered patients. The Mean age of drug onset was 49.42 ±15.25 years. 518 persons (45.3 %) used opium and 330 persons (28.9 %) used Opium sap which were indicated thatthese two drugs were the two common ones among addicted women. In this study 89.2 % of women under-study patients were married, 4.6 % were single and 6.1 % were divorced. Conclusion Presently, the pattern of drug abuse among women in Golestan province is traditional and is based on the opium derivatives. However, according to the increasing rate and changes in drugs type, monitoring the behavior of drug abuser can have an effective role on the improvement of health in a community. Keywords Addiction, Opium, Women A Comparative Study of Explicit Memory between Amphetamines Consumers and Normal people Mahjobe Rahimi1, Nazila Ariaee22, Mahdi Talebi33, Alireza Ghassemi toussi 4 1. M.Sc. of Clinical Psychology, Addiction Research Center, Mashhad University of Medical Sciences Address 2. M.Sc. of Clinical Physiology, Addiction Research Center, Mashhad University of Medical Sciences, Mashhad, IRAN 3. Assistant Professor of Psychiatry, Department of Family Medicine, Addiction Research Center, Faculty of Medicine, Mashhad University of Medical Sciences. 4. Specialist in Forensic Medicine, Addiction Research Center, Mashhad University of Medical Sciences, Mashhad, IRAN Background and Aim In Modern societies substance abuse become a critical issue, since it has destructive effects on cognitive function. Memory as one of the cognitive functions plays a key role in personality, behavior, motivation, emotional processes, and skills of human activity. The purpose of this study was to compare explicit memory in individuals taking amphetamines and normal subjects Methods This was a descriptive-analytic research with comparative design. The population included subjects with and without amphetamines consumption. The sample size in taking amphetamines group and normal people were 35 each of them both equal, subjects were selected by random sampling method. After Stability of clinical condition and relieve symptoms of poisoning, memory of Patients were evaluated with memory recognition test of memory (explicit memory. Data were analyzed by SPSS-18 software. Results Analysis of the data revealed significant differences in explicit memory between two groups. Results of this study show that amphetamines consumer in comparison with normal people has Lower performance in explicit memory (p<0.05). Conclusion Memory processes in amphetamine consumers can identify appropriate functional implications in diagnosis, treatment and prevention cognitive effects of substance abuse. Keywords Explicit Memory, Amphetamines, Cognitive Function, Poisoning Neuropsychological Functions in Tramadol Abusers in Comparison to Normal Subjects Mahjobe Rahimi1, Mahdi Talebi2, Afshari Reza3, Alireza Ghassemi Toussi 4 1. M.Sc. of Clinical Psychology, Addiction Research Center, Mashhad University of Medical Sciences 2. Assistant Professor of Psychiatry, Department of Family Medicine, Addiction Research Center, Faculty of Medicine, Mashhad University of Medical Sciences 3. Addiction Research Center, Mashhad University of Medical Sciences, Mashhad, IRAN 4. Specialist in Forensic Medicine, Addiction Research Center, Mashhad University of Medical Sciences, Mashhad, IRAN Background and Aim Prescription drug abuse and especially Tramadol is on the rise in Iran. Considering the fact that Tramadol is an opioid, it can be associated with some changes in the content and level of consciousness. According to the psychological effects of long-term use of this drug, this study compares the neurological function in Tramadol abusers with normal people. Methods This is a causal - comparative controlled study.Intotals 33 overdose patients including men and women who were admitted in Imam Reza hospital werecompared to 33 normal subjects. Easy sampling was applied. Data gathered from subjects by using neuropsychological tests including Wisconsin Card sorting and stroop test. Results Analysis of the data revealed significant differences in number of errors between two groups p<0.01). Two groups did not differ in terms of the number of errors, but in terms of reaction time, there was a significant difference between healthy subjects and consumers of Tramadol (were more in consumers of Tramadol). S94 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Conclusion Tramadol abuse cans impairs in Cognitive Neural functions .Identifying and understanding these factors may lead to improvement therapeutic strategies. Conclusion Keywords Tramadol Abuse, Neuropsychological Function A study of the characteristics of the Context and the Nature of Activities Conducive for a Community-Based Process (based on the experience of Five Provinces – Mazandaran, Zanjan, Hamedan, Alborz and T Shahryar Rahmani1, Seyed Babak Moosavi Nejad2, Zahra Esfehani3 1. Baznegar Moaser Institute of Development Studies 2. Baznegar Moaser Institute of Development Studies 3. Bureau of Addiction Prevention of the Well-Being Organization This article argues that if the advantages of adopting a community-based approach are to be realized, then it is important to implement the projects in a real community setting. That is why identifying a community by characteristics that are discussed in the article should be considered as one of the more significant steps in the early stages of a project cycle. As for the phenomenon of training, the article does not imply that there is no room for training or educational activities in a community-based process. What is important is that these trainings complement, and do not contradict, the community-based nature of the whole process and this applies to all the activities envisaged for a community-based process. Keywords Community-Based, Community, Training, Projects Background and Aim The bureau of addiction prevention of the Well-being Organisation started to adopt a community-based approach to addiction prevention in 2002, so that communities could begin to take the initiative and responsibility with respect to addiction prevention. There have been obstacles along the way, two reasons of which are examined in this article: (1) aiming to do community-based work in a context where a community – in the true sense of the word – does exist; and (2) the lack of coherence between the type of activities envisaged for community-based projects and the concepts and principles of a community-based approach (with a focus on educational and training activities). Methods The approach to identifying and examining the obstacles to community-based work was group discussions - using participatory methods and techniques - with the implementing staff of the projects and assessing the obstacles with respect to the theory of community-based approaches. Results ing activities can not in themselves be considered as communitybased. This article will shed light on why such projects should – at best – be seen as occasional inputs in bigger, more integrative and more people-centered process. An overall review of some of the community-based projects in the provinces has shown that these projects are often carried out in contexts where there are no communities, or the features expected in a community are very faint. In other words, situations in which it is claimed that community-based activities are taking place do not necessarily have in them the characteristics associated with the term ‘community’. To elaborate on the distinction between a community-based and classic/conventional approach to prevention programmes, this article takes a critical look at some of these project titles and asks whether the claimed community-based nature of a project should be reflected in its title. From another perspective, the type of activities that make up the main components of a project claiming to be community-based should also be different from those of a conventional approach. For example, in a conventional approach, it is normal for educational and informative activities to make up significant parts of the process. However, in a community-based approach, educational and train- The Investigation of Executive Functions in Methadone and Buprenorphine Maintenance Treated Patients Mojtaba Rajabpour1, Azra Ahmadi2 1. PhD Student in Psychology, Mohaghegh Ardebili University 2. PhD Student in Sport Physiology, Mazandaran University Background and Aim Opioid dependent patients under buprenorphine and methadone treatment often show deficits in cognitive and executive functions. However, only a few studies have compared these this study aimed to compare deficits in executive functions among methadone and buprenorphine treated patients. Methods Data gathered from three groups of patients under methadone (31 participants), buprenorphine (31 participants) and control group (31 participants). Stroop test and working memory test were administered on participants. Results Data analysis showed that both patients under buprenorphine and methadone treatment had deficits in working memory and response inhibition. Also, buprenorphine treated patients showed significantly better results in compare with methadone patients in stroop test (p=0.006) and working memory test (p=0.009). Conclusion Our results indicate that although both methadone and buprenorphine result in deficits in executive function, but buprenorphine preserve executive functions better than methadone. Keywords Methadone/Buprenorphine Maintenance Treatment, Addiction Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S95 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Demographic Study of Psychoactive Substance Overdose in Patients Presented to Tabriz Poisoning Center Rouzbeh Rajaei Ghafouri1, Samad Shams Vahdati2, Mehrad Banaei3 1. Emergency Department, Tabriz University of Medical Sciences 2. Emergency Department, Tabriz University of Medical Sciences 3. Tabriz University of Medical Sciences Background and Aim Nowadays, substance abuse and drug intoxication are one of the important medical emergencies and a cause of mortalities in societies. In recent years poisoning cases with opiates and narcotics increase, so prevention and early treatment of these cases have great important role to decrease mortality. Methods The study was an analytical descriptive research. Samples were collected during a six-month period among poisoned patients by psychoactive agents (Amphetamines, Cannabis, Hallucinogens) and/or narcotics (Opiates, Heroin, Methadone,…) who presented to Tabriz poisoning center (Sina hospital). A valid questionnaire was used as a data gathering tool. All patients with diagnosis of opiate and/or narcotics overdoses enrolled the study. Patients coingested with another drug were excluded. Results From total of 227 patients, 167 were poisoned by narcotics, 47 by psychoactive agents and 13 by both of them. Men gender was more than female (86.7%). Although vital signs were normal in 3 groups; but blood pressure, heart rate and respiratory rate were significantly higher in psychoactive agents group (P<0.05). Eighty percent of patients were hospitalized and the rest left the emergency department (P=0.35). There was also 2.2% in-hospital mortality (5 persons). Conclusion Narcotics and psychoactive agents’ overdoses are common in our community. The great portion of them should be hospitalized; however, emergency physicians should be more attentive about these patients. Keywords Narcotics, Emergency Department, Psychoactive Substances Religious Role and Pray in the Prevention of Drug Addiction Parvin Ranjbar Saraydashti1, Aseh Najafnejhad2 1. Education Rasht 2. Education Rasht Background and Aim Addiction is a physical illness–The psychic–Social and spiritual. “This means that in addition to the medicinal intervention for psychological intervention body’s chemical structure change, cognitive and spiritual intervention, as well as community intervention is also involved in treatment can be effective.Today, drug addiction is one of the nation’s most human societies, especiallyMuslim, come and take into account the moral degeneration of the important factor for the weakening of the mental and physical disability of people. Methods Comparison between non-addicted smokers and using the method of interview and questionnaire. Results the human life to religion, he protects against the psychological pressures, and as a result mental health reduce problems as deprresion, anxiety, suicide, low self-esteem and loneliness. as a result mental health,prevention a person’s recreational use or addiction to drugs and alcohol.: Conclusion Based on the clinical interview and questionnaire evaluation of the religious practices of the addictedgroup people have been lax in doing or dont believe to pray and faith but non-addicted in hours of their time to the secret and dread of punishment and their sponsor, has been facing temptation. The French physician Alexis Karl has proven that prayer spiritual vitality in human caused, and decreases the likelihood of drug use, reduces crime in adolescents and a low incidence of divorce in the family. studies in our country shows that prayer is a very meaningful way to reduce anxiety over the effect .on the basis of the results of the research. in Tehran, 68.8% of the non-addicted have that tie to the stated Always read the prayer, but this figure is reduced to 28% in smokers. Also, non-addicted just 6.8% of people do not read the prayer at all, while the figure among those addicted to 14%. In this study, between the lack of adherence to prayer andaddiction a very significant relationship..One of the researchers in the country of Egypt after doing research on it was concluded that the community: on the 63/5% believed that the addiction drug is Haraam and makrooh to 22.5 percent, and 14 percent are legit, but the first batch they were emphasizing medical purposes and because of drug use for therapy, so it will be Two of the researchers in religious groups as a point of research in more as producer consumption, forecasting. This means that membership in religious groups can be very effective in the prevention of drug addiction. Keywords Religious role, Prevention, Addiction. The Relationship between Attachment Styles, Hardiness, Self-Esteem among their Groups - Assistant Addicts Anonymous Narges Rasouli1, Narges, Rasouli2, Qamar Kiani3, Mahvash Mafi4 1. PhD Health Psychology, Department of Psychology, Kashmar Branch, Islamic Azad University, Kashmar, Iran. 2. PhD Health Psychology, Department of Psychology, Kashmar Branch, Islamic Azad University, Kashmar, Iran 3. PhD Health Psychology, Medical Sciences University of Zanjan. 4. PhD, Health Psychology, Department of Psychology, Lahejan Branch, Islamic Azad University, Lahejan, Iran. S96 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Background and Aim The phenomenon of addiction, the drug as a regulator of mood, emotion, and seems to be a key factor in the formation of non-attachment and low self-esteem. There’s so vulnerable to emotional problems in shaping addiction perhaps as the most important factor to be counted as failure in addiction Treatment. Due to this, the aim of this study was to investigate, the relationship between attachment styles, hardiness, self-esteem among their groups - Assistant Addicts Anonymous. Results Methods The research sample of 30 patients in their group - Anonymous Assistant city Kashmar and was used to collect data by questionnaire Kvbasa, Hardiness, Medi and Barton, Reed Collins Adult Attachment Scale and the Coopersmith Self-Esteem Inventory. Results After collecting the data, the results showed that, although the comparison average is effective between attachment and self-esteem but did not show a statistically significant relationship. Also observed a statistically significant relationship between levels of anxiety and self-esteem in people with substance abuse (p <0.05). Conclusion Although past studies have reported showing the relationship between attachment and addiction, But in the study of anxiety and its effect on self-esteem predicting drug was approved formation as an important factor. And it seems to justify indirect, may come to account anxiety and self-esteem predicted attachment. Keywords Addiction, Hardiness, Attachment Styles, Self-Esteem, Groups - Assistant Addicts Anonymous. Neuron- Linguistic Programming for Making Ready to Decline and Give the Consuming Drugs and Methadone up Between Prisoners Iman Lashani , Mohammad Razaghi , Sakineh Akbari Fard 1. Psychology and Training Sciences Department, Zahedan University, Zahedan, Iran 2. Humanity and Litrature Department, Guilan University, Rasht, Iran 3. Psychology and Training Sciences Department, Allameh Tabatabaei University, Tehran, Iran 1 2 3 Background and Aim Addiction is chronic and harmful disease that affects on all aspects of addicted person’s life. Also addiction to the drugs can be one of the serious psychosocial traumas. Today one of the most useful and common ways to treat addicted prisoners in Iran’s jails is using methadone maintenance treatment (MMT) that is not only expensive but also causes some kind of serious tribulations for stickmen. In this study we have tried to investigate the ways for making addicted prisoners ready to stop or decrease using drugs by Neuron- Linguistic programming method. Methods groups who consume MMT in Doroud’s prison. 30 people were selected between clients and randomly they were divided in two groups who due to quitting the study by four addicted prisoners, we had 11 people in experiment group and 15 in control group. For collecting data, we have used readiness questionnaire to change and stop using drugs (Miller, Tonigan, 1996) and changing the amount of consuming drugs between addicted prisoners weekly. For analyzing covariance and chi2 test has been used. This study has done by semi test method along with control According to the results, experiment group’s scores in subscales’ readiness to change and treat consuming drugs, include recognition and ambivalence and going ahead, posttest and following test showed significant increasing compared with pretest which this change couldn’t be considered in control group. To investigate weekly consuming methadone between consumers, significant decreasing was considered in experiment group and we used chi2 test to be sure about the result which has shown us significant difference between two groups in consuming methadone at the end of instruction career (2X= 13/23, P = 0/00) and following steps (2X= 9/01, P = 0/00) . According to the experiment group’s priority compared with control group, in giving consuming drug up (28/57 opposite of 0/5), investigating significance of the results by X2 test, significant difference couldn’t be considered (2X= 3/60, P = 0/058) Conclusion Although the method couldn’t show a completed success to stop consuming drugs between consumers; but, as a motivating and useful way, it could show its affection on decreasing and going ahead in primary steps of consuming drug. At the end, we can say applying Neuron- Linguistic programming method can cause optimized changes in psychological condition of people and help them to decline and stop consuming drugs. Keywords Addiction, Neuron- Linguistic programming, Consuming Drugs and Methadone, Prisoners Comparing the Effectiveness of Cognitive-Behavioral Group Therapy (CBGT) with transtheoretical Group Model in Reduction the Verbal Aggression in Addicted Offenders Davood Razi Roody1, Bahramali Ghanbari Hashem Abadi2, Elnaz Foroughi3, Ali Babaei4, Asadollahi Javad5, Ali Rajaei6 1. Chenaran’s Occupational Camp 2. Faculty member School of Education and Psychology, Ferdowsi University 3. Student Psychology, Azad Islamic University of Torbat-e-Jam 4. Head of Science - Applied the Six Nations, Prisons Organization 5. Student Family Counseling, School of Education and Psychology, Ferdowsi University 6. Faculty Member Azad Islamic Torbat-e-Jam Background and Aim One of the sub-layers of aggression is verbal aggression which includes insults, contempt, slander, backbiting, labeling and mocking. Although all examples of this type of aggression are not known as so-called “crime”, they can predispose physical ag- Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S97 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall gression and social misbehaviors in interpersonal relationships, in particular among addicted Offenders. Using Psychotherapeutic methods has been considerable research attention to reducing persons’ verbal aggression, especially addicted offenders. The present study is an attempt to compare the effectiveness of cognitivebehavioral group therapy and trans-theoretical group therapy in reducing the addicted offenders verbal aggression of Chenaran’s occupational camp. Methods statistical socity consists of all of the prisoners in Chenaran’s occupational therapi’s camp. From 3000 people in this camp, 24 participants are chosen because of the result of the verbal aggression in pretest and also have these two factors: lived there at least about 6 month and have the minimal cycle, are going to be statistical samples. These 24 participants are divided randomly in 3 groups that everyone consis of 8 participants. The groups are group A, B and C that Group A is cognitive behavior therapy, Group B is transtheoretical therapy and group C is control’s group that are in the waiting list. This research design is multiple groups which consist of two kinds of pre-test and post-test with experimental and controlled groups. The sampling was random and systematic. Gathering the data’s instrument was aggression questionnaires of Buss and Perry were used before and after the interventions. Because there were 3 groups and pre-test was available, the ANCOVA’s model was used. The SPSS software was used to expedite the results. tive outcomes, which this response makes it difficult for the addicted person return to the society after treatment. We aimed to develop a model of rehabilitation proposed, in order to identify priorities in the allocation of services and support for people with addiction after leaving treatment. This is a small-scale survey which was conducted in1391 in the city of Mashhad. Methods with the accessible sampling method, which the number of subjects selected are chosen by the grand theory method. The need assessment in this study consists of two stages. Firstly, semistructured interviews with 42 people with the use of outpatient facilities, inpatient and community-based treatment were referred to the city of Mashhad, and 31 cases of the treatment team (physician, psychiatrist, psychologist, social worker), and in the second stage, semi-structured interviews with a team of specialists, including 18 psychiatrists, 13 psychologists and four social workers in the field of addiction prevention and treatment took. The collected data were analyzed using statistical descriptive phase encoded in the first and second stage, and presented as bar graphs. Results The graphs of the first stage showed that the most needs of addicts after leaving the treatment is in areas such as; the employment, improving relationship with family, controlling and managing anger, sadness and deal with the temptation was determined. Conclusion Results The results of covariance analysis showed that the degree of verbal aggression of Cognitive-Behavioral Group Therapy in post-test was meaningly less than pre-test. The average of verbal aggression degree of transtheoretical group model in post-test was meaningly less than pre-test. Also these results showed that the effect of transtheoretical group model was more than CognitiveBehavioral Group Therapy in reduction the verbal aggression. Conclusion Although both of Cognitive-Behavioral Group Therapy and transtheoretical group model were effective in reduction the Addicted Offenders verbal aggression, But the effectiveness of transtheoretical group model was meaningly more than the CognitiveBehavioral Group Therapy. Keywords Cognitive-Behavioral Group Therapy, Transtheoretical group Model, Verbal Aggression, Addicted Offenders Rehabilitation Modeling of Addiction Therapy Maryam Rezaeeboroon1, Maryam Rezaee-Boroon2, Elahe Azizi3, Hasan Hagipour4 1. Revention Department of Khorasan Razavi Welfare Organization 2. Prevention Department of Khorasan Razavi Welfare Organization 3. Prevention Department of Khorasan Razavi Welfare Organization 4. Prevention Department of Khorasan Razavi Welfare Organization Background and Aim Substance dependence disorder is associated with many nega- The results showed that after treatment care for addicts, we can suggest patterns based on the needs of addicts and experts. Keywords Needs Assessment, Grand Theory. Allocation of Services Nutritional Management In Alcohol Addiction And Substance Abuse Recovery Nadia Rezaei1 1. School of Nutrition and Food Sciences, Shiraz University of Medical Science, Iran Background and Aim Mounting interest in the potential value of nutritional management in the treatment of alcohol and substance addiction has arisen as a result of the growing body of evidence implicating nutritional interventions can play an important role in recovery and lead to improved outcomes. The purpose of this review is focus on the role of nutrition (micronutrients/macronutrients) in the alcohol and substance abuse recovery. Methods Articles in this review were identified through an electronic database search. Results Good nutrition plays an important role in successful detoxification from alcohol and drugs abuse. Most addictive substances cause negative lifestyle changes, such as irregular eating and can S98 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall significantly damage or even shut down the digestive processes. The damage of the delicate inner lining of intestines caused by chronic alcohol or heroin abuse impairs the absorption of amino acids, vitamins and minerals and many addicts experience digestive problems such as constipation, diarrhoea, indigestion and poor appetite.Most addictive substances strip the brain of essential fats, as well as impair absorption and utilization of amino acids necessary for neurotransmitter synthesis. Nutritional deficiencies can play a big role in the development and perpetuation of brain and cognitive dysfunctions and induce immunodeficiency and may influence susceptibility to other infections such as HIV. Essential fatty acid deficiency is production of the neurotransmitters adrenalin, dopamine and serotonin. These linked to anxiety as well as relapse.Phenylalanine, tyrosine and tryptophan are responsible for compounds are essential for emotional stability, mental clarity and a general state of well-being. Increased dietare intake of tryptophan has been shown to stabilise mood, improve sleep and reduce frequency and severity of alcohol withdrawal symptoms during early stages of alcohol detoxification and possibly improve cognitive functions of abstinent chronic alcohol abusers.Supplementation with phenylalanine elevates mood, increase confidence, motivation and energy levels, and indirectly decrease drug cravings.Tyrosine supplementation increases energy and emotional/mental alertness.Micronutrients(vitamins and minerals) particularly B-vitamins and antioxidant vitamins (A, E and C) play crucial roles in brain physiology.The vitamin B complex is essential for the overall cerebral cognitive performance as a lack of pyridoxine and riboflavin overloads the “gammaamino butyric acid (GABA) shunt, thus resulting in an excess of glutamate production and neuronal death caused by a glutamate overexcitement (excitotoxicity). Thiamine prevents the development of Wernicke-Korsakoff psychosis.Medical drugs just block the action of adrenalin or stimulate temporary excessive release of pre-existing neurotransmitter stores. They do not increase the production of neurotransmitters, thus amino acid therapy together with multivitamin and mineral supplementation should be considered during the early stages of alcohol and drugs recovery and possibly continued by following a healthy diet. In some worst cases (ie. chronic addicts or when intestines are severely damaged), short-term intravenous nutritional therapy may be required so that bypass a severely damaged gut. Conclusion Drug addicts have a special need for foods that are high in nutrients to rebuild damaged tissues and organs. Simple changes in dietary habits, optimising the intake of the amino acids, vitamins,minerals and essential fatty acids is the long-term way out of addiction. Keywords Micronutrients, Macronutrients, Nutritional Management, Substance Abuse Correlation between Assertiveness Skill and Smoking in Male Students Living in Dormitories of Isfahan University Background and Aim The student years, a period that the risk of smoking and become familiar with the model for the consumption increases. Studies conducted in the United States indicate that approximately 30 % of these students smoking in the past 30 days, and 40 % of them have reported smoking in the past year. Several factors such as curiosity, pretending to maturity, the typical opposing parents, freedom from social pressure, socializing with smokers and smokers in the family have expressed the tendency of individuals to smoking. One of the most important attitudes that can affect the social, professional and personal, especially medical students influence is decisive. Studies in other countries show a determination not to accept those who have higher skills, less tobacco use .and teach them to be expensive, recognition, prevention and treatment of physical and mental health of each factor and the resulting adverse impact on its performance may seem necessary. Methods This was a descriptive comparative study in this type of correlation is consistent. To achieve its goals, 171 male students living in University residences were studied. The questionnaire consisted of demographic characteristics, smoking and Gmbryl and Ritchie is firmly scale and sampling was done randomly in two groups of students were smoking and nonsmoking students completed questionnaires. To analyze the data, descriptive and inferential statistical methods and software spss version 18 was used. Results Results of statistical tests show that the mean firmness of the group of students who smoke 93 ± 59/20 and the mean score firmness research students nonsmokers 91/88 ± 75/20 is the average score of resolute group of male students , there are significant differences between smokers and non- smokers, (00/0= P). Statistical correlation between the degree of decisiveness and variables , father’s education , family attitudes toward the field of education, economic status , Discipline and cigarette smokers in the group of students demonstrated between the number of cigarettes smoked and the determination of the group of male students who smoke , according to Pearson correlation test , there was no statistically significant difference (454/0=p). Conclusion According to these findings, it is concluded that smoking is strongly related skills. According to the results of demographic factors, such as smoking appears that the participants in this study might be due to other factors. However, smoking as a cause of impaired drug dependence can be caused by factors other than resolution skills. Stress academic environment and separation from parents, friends also modeled in such environments can be associated with smoking that more studies are needed. Keywords Assertiveness Skills, Smoking, Students Sara Rezaii1 1. Kashan University of Medical Sciences Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S99 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Determination of Serum Sodium and Potassium and Electrocardiographic Changes in Tramadol Toxicants Fares Najari1, Ali Roboubiat2 1. Shahid Beheshti Medical College- Forensic Medicine and Clinical Toxicology Group Office 2. Shahid Beheshti Medical College- Forensic Medicine and Clinical Toxicology Group Office Background and Aim Tramadol or Ultram is an opioid like drug that today extensively in Iran abused by and its side effects. electrocardiographic changes and other symptoms of a heart that is the new reports from all of the word in this pateints that can be potential danger of cardiac arhythmias Methods All toxicants only with Tramadol within one year of admission to the emergency poisoning entered to this prospective survey ,(n = 1402 patients) venous blood samples for testing serum levels of sodium and potassium and ECG obtained . Then probably ECG change associated with drug toxicity, are determined and along with age and gender was written in the form of special questionnaires.Then all obtained data, based on statistical tests were analyzed by descriptive and inferential spss software. Results The total number of 1402 patients were studied that 997 patients were male (71.1% of patients) and 405 females (28.9% of patients). Minimum age were at 14 years and maximum age 53 years. Lowest serum sodium in patients was 132 and maximum values was157 mEq/ dL. Hyponatremia observed in 3.6% of patients.hypernatremia in 0/05 % Of patients was seen.Minimum serum potassium level was 3 and maximum serum potassium level was 6.1 meq/dl. Hypokalemia was seen in./67% of pateints. hyperkalemia Were seen in 1.6% of patients. sinus tachycardia (HR> 100 / min) in 33% of patients was seen . sinus bradycardia ((HR <60/min) in a male patient (/.5/.% of patients) was seen. evidence of an increase in PR interval was not seen in any of the patients. Duration of QRS, 120 ms and more In 5/6% of patients was observed. Duration of, QTC than 440 ms in 18.4% of patients was observed. A height of R wave more than 1 mm in aVR lead in 24.3 % of patients was noticed. presence of S-wave dominance in one of the leads I or aVL in 28.1 % of patients was observed. pattern of Brugada in./1 % of patients was observed. Conclusion With regard to this study and other studies conducted earlier can be concluded that Tramadol intoxication associated with degrees of block sodium and potassium channels in the heart and it can potential theoretical progress in to a severe ventricular arythmia Keywords Tramadol-Sodium-Potassium-Toxicants The Relationship Between Tendency to cheating, Big Personality Traits and Educational Self-Efficacy: a Case Study of High School Students in Yazd Province Romina Roohi1, Mohammad Nazer1,2, Romina Rouhi3, Nooshirvan Khezri4 1. Department of Psychiatric, University of Medical Sciences, Rafsenjan,Iran 2. Department of Psychiatric, University of Medical Sciences, Rafsenjan,Iran 3. Department of Psychiatric, University of Medical Sciences, Rafsenjan,Iran 4. Department of Psychiatric, University of Bahonar, Kerman, Iran Background and Aim Fraud is committed as a common phenomenon in educational environments such as schools and universities as cheating on examinations and doing homework. In this study, the relationship between tendency to cheating, educational self-efficacy and five big personality traits among high school students in Yazd province are studied. Methods Research method was correlational which was conducted based on Morgan Table on 260 students who were selected from 6 schools in 3 fields of study using cluster random sampling method. Research tools included neo personality scale, Morgan and Jinks student efficacy inventory, Sepehrinia test for assessment of tendency in cheating, and scientific information test. Results In boys all big personality traits except openness prognosticated attempting to cheat. In girls only accountability did prognosticate attempting to cheat. The highest correlation coefficient was 0.478 in boys which was related to neuroticism. The highest correlation coefficient in girls was 0.20 which was associated with accountability. The twenty percent variance in the variable tendency to cheating is defined by self-efficacy in boys, and 15% in girls. The correlation coefficient between committing cheating and tendency to cheat was 0.474 in boys and 0.230 in girls. Conclusion It can be concluded that there is a relationship between educational self-efficacy and five big personality traits. Also the inclination to cheat may foresee cheating. Keywords Cheating, Tendency to Cheat, Educational Self-Efficacy, Personality Trait, High School Adolescents. Effectiveness of Life Skills Education on Increasing Protective Factors for Substance Abuse in Adolescents (Case Study Bidestan) Kolsoom Roshan Qias1, Ail Ahmadi 2, Ahmad Abrahimi 3, Reza Rishpour4 1. MA, Eductional Managemant, Teacher of Oloom-e Behzisti University of Qazvin 2. MA, Public Managemant , BM of Nursing. , Faculty Member Manager Nursing Qazvin, Teacher of Elmi Karbordi University (visitor_5671@yahoo.com) 3. PhD Student in Social Work , Science Centers and Teacher of Oloom-e Behzisti University of Qazvin 4. MA in psychology Teacher of Oloom-e Behzisti University of Qazvin S100 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Background and Aim Adolescence is a critical developmental period that is associated with the process of identity formation Part of this growth process, risk-seeking the form of unhealthy sexual behaviors and alcohol, tobacco and other substances may be present. Epidemiological studies indicate that smoking Alcohol and other drugs among adolescents in different societies in recent decades have witnessed an increase in the aim of this study was to evaluate the effectiveness of life skills training on enhancing protective factors in adolescents was Bidestan Methods In this quasi-experimental study of 150 adolescents Shhrbydstan (experimental group, n = 75, control group n = 75) Randomly selected as the experimental group received eight sessions of life skills education. The main instrument questionnaire protective factors for substance use Mohamadkhani (1390) was Results Results showed that scores on the variables of attitude toward the material, depression and sensation-seeking group was less than control group variables courage and self-control abilities of the group Conclusion Teaching life skills in adolescents is increasing protective factors. Drug abuse education, life skills and coping skills may be particularly attitudes Significantly altered the ratio of drug use and their tendency to reduced drug use. Keywords Education, Life skills, Protective Factors, Adolescents City Bydstan Drug Abuse and Sex Working in Tehran Metropolitan Payam Roshanfekr1, Mohammad Ali Mohammadi 2, Saeid Madani Ghahfarokhi3 1. Social Determinant of Health Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 2. Social Welfare Management Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 3. Social Welfare Management Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran Background and Aim while the problem of addiction was always considered masculine, gradually in recent years the share of women drug users’ population have been rising. This paper is trying to explain the dual relationship between women drug abuse and prostitution in Tehran, Iran Methods This study is a cross sectional random sample survey of female sex workers in 22 regions of Tehran . A sample size of 300 people was designed in 40 units of 6 to 8. Results The findings are presented in two parts; the first part includes the factors which are associated with drug use before starting the sex work; and the second part focuses on the status of drug using after starting the sex work. Two main factors associated with the drug use before starting the sex work, are parents’ drug use, as well as husbands’ addiction. 46.2 % of the respondents have confirmed their father use of the drug and 20.2 % that of their father being arrested and imprisoned before starting the sex work. Moreover, 13.6 % of her mothers have engaged in sex work themselves, 8.4 % have experienced drug use, and 4.4 % have experienced arrestment or imprisonment. 56.6 % of the husbands of 156 female sex workers, who have experienced marriage, have a history of drug use. 33.7 % of these women have used injection of the drug by their husbands. 84.4 % of the female sex workers who have used drug one month before the present study have reported drug use before having sex. This behavior indicates women’s low level of consciousness during the sexual intercourse and thus increases the probability of high risk behavior. There is a significant relationship between the injection of drugs during the last month and the period of the sex working. In other words, the longer the time of the sex work, the more probable the injection of the drug. The study of the relationship between Risky behavior and the background and professional variables shows that the frequency of this behavior is higher in the age groups less than 25 years compared to other groups during the last month. Moreover, the frequency of this behavior is affected by two factors: an increase in the income and increase in the duration of sex work. This behavior is more common among those who have no especial place of standing to attract customers, a group mainly in the West of Tehran, also divorced sex worker. Conclusion Drug abuse before sexual intercourse can reduce the level of consciousness and increase the possibility of occurrence of high risk behaviors. Most of the street women possess HIV risk, among them intravenous drug addict prostitutes who do not use condom for more money, are heavily at risk. Keywords Sex Work, Drug Abuse, Women, Risky Behavior Harm Reduction Programs as an Effective Intervention in Iran Prisons Payam Roshanfekr1, Marziyeh Farnia 2, Masoumeh Dejman3 1. Social Determinant of Health Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 2. Iran Prisons Organization, Iran 3. Social Determinant of Health Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran Background and Aim In Iran since the 1990s various services under the title of HIV/ AIDS prevention and control programs have been initiated in prisons in accordance with the policies set by the Ministry of Health and Medical education, including education and awareness of inmates and their families, informing officials and key decision makers, setting up triangular clinics or consultation facilities on Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S101 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall behavioral diseases in prisons and rehabilitation centers. Therapeutic programs for substance dependency include detoxification, medication-free psychotherapy, agonist treatments, and prevention and care programs for uncontrolled sexual behaviors (by providing inmates with private rooms to meet their spouse), condom availability at triangular clinics, identification and treatment of sexually transmitted disease (STD) patients in triangular clinics, and counseling of spouses of prisoners by midwives or health . The current study was designed to statistically assess the effectiveness of harm reduction programs related to drug use and substance dependency in 7 large prisons of Iran (Karaj, Gorgan, Zahedan, Orumiyeh, Bandar Abbas, Yazd, and Kermanshah). Methods The study is based on the research-experimental design known as the before-after or the one-group pretest-posttest design. In this test, Sample size was 2,200. Filling questionnaires and conducting drug tests using 4 drug-type kits upon admission of prisoners to the facilities indicates that around 57 subjects were addicted to at least one of the three drugs of morphine, hashish or amphetamine (52% to morphine, 9.3% to hashish, and 5.4% to amphetamine). Prevention and control services were offered to all newlyadmitted prisoners under study as well as to other inmates. Services included detoxification, maintenance care, self-help group therapy, motivational interviews, psychiatric treatment, needle exchange and injection equipment distribution programs, cognitive-behavioral treatment, HIV testing and counseling, disposable razorblade distribution, and self-help services. Two months later, a 2nd set of questionnaires and drug tests were administered to in-prison subjects using the same kits as in the previous phase. Results Each of the subjects was tested to determine which of the three drugs of morphine, hashish, or amphetamines they used most. 56.7% of subjects were addicted to one of the three substances (47.6% were addicted to morphine, 9.3% to hashish, and 5.4% to amphetamines). After two months, 605 subjects (or 27.5%) of the total 2,200 sample population of the 1st phase were still in prison and the rest were set free. Collected data based on interviews with remaining prisoner in the 2nd phase indicates that only 10% had used drugs over this period. We compared drug test results obtained from subjects participating in the 1st and 2nd (two months later) phase of the study using the paired student’s t-test and difference is statistically significant Conclusion This fact and the aforementioned research findings makes clear the necessity for the continuation of implementing effective intervention programs supported by strong theoretical and analytical research, leading to harm reduction and control of drug use in society. Keywords Harm Reduction, Prison, Intervention, Drug Abuse, Substance Dependency, Interventions High-risk behaviors of women using substances: a qualitative study in Tehran, Iran Payam Roshanfekr1, Roya Noori 2, Masoumeh Dejman3 1. Social Determinant of Health Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 2. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 3. Social Determinant of Health Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran Background and Aim Behaviors directly and indirectly with profound influences on individual and society’s health and those with negative consequences for them are called “high-risk behaviors”. Various studies in Iran have suggested high-risk behaviors in youths and adolescents but there are fewer studies concerning high-risk behaviors in women. However, findings of a study by Razaghi et al. showed that women’s proportion rate for addicts population has been gradually increased since the early decade of 2001. The current study is one of the few studies that preliminarily explored the initial reasons associated with drug use and sex work among a group of women who were seeking drug treatment in Tehran. Methods Thus, this was a qualitative study with in-depth interviews and group discussions with 47 women referring to addiction treatment centers or harm reduction therapy centers for addiction causes and high-risk sexual behaviors in Tehran, Iran. Results Findings showed that approximately half of the women (48.5%) used to earn money through prostitution. Their mean age was 34.7 years and 85.5% of them have experienced a non-single life. Obtained reasons for women’s addiction were categorized in three main categories; i.e. enforcement or encouragement by others (including family, husband, friends, and strangers), underlying conditions predisposing the consumption (in family and environment) and/or personal need or desire (decreased pain, impotence, rejection tolerance, joy and curiosity seeking). The reasons of prostitution in the two groups were also supplying family funds and costs (substances or living) and living conditions and background. The association between prostitution and substance addiction was both cited as casual (each is the cause of the other) and co-occurrence and co-variance. Conclusion Special drug treatment and supportive services should be provided for female sex workers in Iran. Additionally, staff training and education should be provided in Iran when female sex workers enter treatment for drug use.The study findings showed a number of reasons associated with initial drug use and sex work among the sample. The role of sex work in providing drug has critical health and clinical implications. This issue should be further studied in more representative samples of drug-using women especially sex workers in Iran Keywords High-Risk Behaviors, Health-Risk Behaviors, Prostitution, Addicted Women, Substance Abuse, Co-Occurrence S102 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall The Prevalence of Alexithymia in the Patience who Participated in Rehabilitation in West of Mazandaran Shokoofeh Rostamynezhad1, Rostamynezhad Shokoofeh2, Sayadi Daryoush3 1. Master of Clinical Psychology Field, Islamic Azad University of Tonekabon 2. Master of Clinical Psychology 3. MD Background and Aim Yet another dimension of mental disorder is claimed to be Alexithymia which plays a crucial role among drug addicts and their further dependency so this study has attended to establish a link between Alexithymia and addiction in rehab clinic participants. Participants and statistical sample for this study was formed 304 male individuals under 50 years old that were randomly selected among rehab clinic participants in West Mazandaran in 1392. Toronto Alexithymia scale (TAS _ 20 1994) was enabled Methods Ferequency, ferequency percentage, T test, one way variance and Scheffe_test This study was conducted using the case – control method. Sampling was non-randomized. Data was collected through interviews and by social control and social support questionnaires. Data analysis was based on by Chi-square test, independent sample t-test and logistic regression. Results Social commitment, social isolation, attitude to drug abuse, use of recreational facilities, cultural and social support, were significantly higher in resilient Group than in non-resilient (control), group. There was not any difference between two groups about social control. Logistic regression analysis of variables showed that social control, attitude to drug abuse and using recreational - cultural facilities are predictors of resiliency against drug abuse. Conclusion Findings of this study showed that social control, attitude to drug abuse and recreational - cultural facilities are major determinants of resiliency against drug abuse in the sons of addicted fathers. Keywords Results 201individuals (67%) were diagnosed with Alexithymia ranging from acute to very acute. Furthermore secondary results show there is no difference in intensity of these signs among single or married participants, but among people with various literacy level under BY and diploma, results were meaningfully different. Conclusion Alexithymia is a learning trait. With traning people to identify and describe their emotions, they can be prevented from addiction. Keywords Alexithymia, Ranging , Dependency Resiliency against Drug Abuse in the Male Offspring of Addicted Fathers: the Role of Social Variables Mohammad Sabzi Khoshnami1, Hassan Rafiey2, Hadi Motamedi3, Fardin Alipour4 1. University of Social Welfare and Rehabilitation Sciences,Tehran,Iran 2. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 3. University of Social Welfare and Rehabilitation Sciences,Tehran,Iran 4. University of Social Welfare and Rehabilitation Sciences,Tehran,Iran Background and Aim Methods Today, addiction is one of the most essential social deviances. Many factors influence the tendency of people, especially the young to drugs .Parents addiction, can a trigger for family distortion and tendency of other members to addiction. However, in these families, there are people who despite parents with substance abuse and addiction problems, so they have resiliency to the drugs. In this study we examined the relationship of social control and social support with resiliency against drug abuse in the children of addicted fathers Addiction, Drug Abuse, Male Offspring of Addicted Fathers (Sons of Addicted Parents), Resiliency, Social Support and Social Control. The Measurement of Validity and Reliability of Resiliency Questionnaire Connor and Davidson (2003) the Resiliency at Against Addiction father: from Variable Definition to Case Definition Hassan Rafiee1, Mohammad Sabzi KHoshnami2, Gholamreza gheedamini3, Fardin Alipour4 1. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 2. Social worker, Faculty of Social Welfare and Rehabilitation Sciences University, Tehran 3. Student , PhD of Social Welfare, University of Social Welfare and Rehabilitation Sciences, Tehran 4. Student , PhD of Social Work, University of Social Welfare and Rehabilitation Sciences, Tehran Background and Aim The measurement of resiliency need to a valid and reliable scale. Resiliency scale Connor-Davidson (CD-RISC), is one of the most common scales for measure of resiliency. The main objective of this study was measuring resiliency scale psychometric characteristics of the Connor-Davidson (CD-RISC) in the sons of addicted fathers. Methods This study was conducted using the causal- comparative method. 102 Sons of addicted Parents, that living in Tehran province were selected via purposeful sampling. For this aim we used criterion validity (known-groups approach) and construct validity and scale reliability and Cronbach’s alpha coefficient. Results The first criterion for the validity of the paired T-test was used and Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S103 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall 25 questionnaires asked seven resiliency Between the two groups were not significant in the new questionnaire were excluded and the question was reduced to 18. Exploratory factor analysis with two other items were removed, and finally with 16 items in four factors (related attributes), having internal and external resources, Ability and sense of hope, tolerance and strength and hard work were identified. Confirmatory factor analysis model that is also¬ fit four-factor data are shown. To determine the cut-off point, the sensitivity and specificity of the questionnaire Connor and Davidson we used ROC curve. the Area under the curve for this the questionnaire was CI: 0,617-0,817) 0,717 ;( p<0,001).Cronbach’s alpha for the entire scale as well as 0.91 was obtained. Conclusion The results suggest that the short form questionnaire have a good validity and reliability. But we think for using in other populations precautions should be considered. And thus to case definition the resiliency approaches. Keywords Male Offspring of Addicted Fathers (Sons of addicted parents), Conner & Davidson, Cut-off Point, Resiliency. The Ethical Challenges of Addiction Medicine in Iran Said Abbas Sadat Hosseini1 1. Lawyer and assistant professor Of Forensic Medicine,Head Of Medical Ethics Department,Shahid Sadoughi University Of Medical Sciences Of Yazd,Yazd,Iran Background and Aim We aimed at treating addicts as patients and studied the medical approach towards them from the viewpoint of medical ethics in Iran. Methods Library research Results The figures and statistics related to the addict population and its humanistic and financial expenses are worrisome so that it has led the Iranian state to implement encouragement programs of addiction-cessation and self-treatment in state or private medical centers as a complement to the physical fight against the entrance and distribution of drugs. Each individual’s participation in any medical issue requires informed consent and maintenance of independence and autonomy. The first and the most basic measures in this regard is the correct and appropriate introduction of medical centers to the receivers of services. Is “Addiction Treatment Center” or “Addiction Give-up Center” ethically suitable for the performance of these centers? Is the ability of medical sciences in treating these individuals in order to restore their health and remove the psychosomatic effects of drug abuse? Is not the term “helping to give – up addiction” more proper so that these individuals are not given any unrealistic hopes? Does not the devotion of medical centers for addicts or their presentation in these centers especially in small towns, where most people know each other, lead to their shame and humiliation in front of people and disclosure their addiction? As medical practice is a fully professional job and the provision of service is superior to any other benefit specifically personal profiteering, do the practitioners have a strong belief in solving any of these individuals’ and their families’ problems or do they add further costs to their current expenses or add a new addiction to their present ones? Of course, this does not mean the inadequacy of these centers; rather, it emphasizes the need for the practitioners’ carefulness in these centers in using the applied scientific methods and also the lack of profit from these individuals and their relative. One type of justice less dealt with in medical ethics is equity; namely respect to this golden principle: “behave the others the way you like to be behaved”. The physician should not treat the addicts in a way that they think they are untreatable patients who should be thrown away from the illegal market of consumption and put into another field that is more controlled. On the contrary, they should be given the necessary information and behaved properly so that they can regain their self-confidence, self-esteem and self-worth. Conclusion Addiction caused by several factors that it may not be same or specified in all individuals. The Medicine should be act cautiously and based on careful scientific, social, economic, legal, and ethical facts facing addiction. Otherwise, it may lead to lack of confidence in the medical practice and treatment, this being an important ethical issue. Keywords Ethical Challenges, Addiction, Approach, Iran The Nature of Drugs Abuse Insanity from the Criminal Law viewpoint in Iran Said Abbas Sadat Hosseini1 1. lawyer And Assistant Professor of Forensic Medicine, Medical Ethics And Law Research Centre Of Shahid Beheshti University Of Medical Sciences,Tehran,Iran Background and Aim The study of the features and characteristics of Drugs Abuse Insanity from the viewpoint of the Islamic Penal Code of Iran. Methods Library research Results The definition and identification of insanity have been always controversial among specialists in medicine and law. It seems that the definition and diagnostic criteria of insanity are constantly changing with scientific developments in medical fields while it has not been the case in legal fields. Furthermore, the jargon used to describe or refer to the affected individuals has not been the same; insanity is used in law and psychosis in medicine. In the law of Iran whenever we point to insanity and insane, for any reason and any degree, we pursuit a purpose; it is the insane incapability in performing of any legal action or the possibility of offense. In the new regulation of Iran the law has identified insanity and defined it as a state of a person who is suffering from mental disorder and who doesn’t have any will and distinction capability. Regarding mental state resulted from drug abuse, this S104 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall act, in article 154, establishes: The drunkenness and passivity due to voluntary abuse of intoxicants, abused drugs, psychotropics, etc. do not preclude punishment unless it is proved that the person committing it did not generally have any free will. The basis of insanity determination and insane identification is the capacity for the intention of commitment of a crime and expecting its result. The cause of insanity is not important unless in the case of insanity resulted from drug abuse. So, if the drugs are abused for crime and insanity develops as its effect, the responsibility rests. Now, by this legal definition of insanity, it doesn’t seem that the insanity resulted from drug abuse corresponds to the medical definition of insanity. If physicians are asked what the meaning of free will and power to will is, perhaps they can’t respond scientifically. Also, it may be the case that the mental disorder based on Abulia doesn’t have any scientific justification. Conclusion Our judges should not limit themselves to psychiatrists’ opinions; rather, they should pay attention to the conditions governing how criminal acts happen and what criminal’s intention has been. For example, from the medical viewpoint, it may be that the person commits an insane sexual behavior under the influence of some drugs. This does not mean involuntariness or lack of intention especially failure to distinguish the criminal act by the poisoned person. Rather, we should study the conditions governing the crime including whether the victim has been male or female, elderly or young, incest or not, invasion happened in solitude or in crowd, the criminal has selected the victim or he/she has invaded the first available person, what the criminal has done against victim’s or others’ resistance, and many instances that are proposed and we should consider them. Keywords Drugs Abuse; Insanity; Iran; Law Conclusion Considering the TC outcome in other countries, it seems that TC maintains an acceptable effectiveness in Iran. Prospective controlled studies are warranted to investigate the outcomes in more details Keywords Therapeutic Community,TC Program Repetitive Systemic Morphine Alters Activity-Dependent Plasticity of Schaffer–Collateral–CA1 Pyramidal Cell Synapses: Involvement of Adenosine A1 Receptors and Adenosine Deaminase Mehdi Sadegh1, Yaghoub Fathollahi2 1. Department of Physiology, School of Medical Sciences, Tarbiat Modares University, Tehran, Iran 2. Department of Physiology, School of Medical Sciences, Tarbiat Modares University, Tehran, Iran Background and Aim The effectiveness of theta-pulse stimulation (TPS) for the reversal of theta-pattern primed bursts (PB)-induced long-term potentiation (LTP) were examined at the Schaffer–collateral–CA1 pyramidal cell synapses of hippocampal slices derived from rats chronically treated with morphine (M-T). Methods Effectiveness of Therapeutic Communitymodelin Iran (I.R.) in vitro fEPSP- and PS were recorded. Results Nasrindokht Saddir1 1. Behzisty Organization Background and Aim Evaluation of treatment programs in addiction field is a prerequisite to improve the quality of care. This study aimed to investigate the effectiveness of Therapeutic Community (TC) program in Iran Methods Individuals who had voluntarily enrolled in the TC center within a period of seven years, from early 2005 to late 2011, entered the study. Those who successfully completed the 14-week residential course were considered as ‘completers’. They were subsequently called in for urine test and interviews using Maudsley Addiction Profile. Urine test was conducted to determine if they were positive for heroin, opium, methadone, methamphetamine, buprenorphine, hashish, and tramadol Results 7.8 enrolled in the TC program during the study period, 240 individuals of whom completed the 14 weeks course (69.0%). At the end of the sixth year, 22% of the participants were in abstinence. Physical and mental health in abstainers proved to be of better conditions than those of non-abstainers (P<0.05). A number of 378 individuals with mean (± SD) age of 32.5 ± The results showed that slices derived from both control and M-T rats had normal field excitatory postsynaptic potential (fEPSP)LTP, whereas PS-LTP in slices from M-T rats was significantly greater than that from control slices. When morphine was applied in vitro to slices derived from rats chronically treated with morphine, the augmentation of PS-LTP was not seen. TPS given 30 min after LTP induction failed to reverse the fEPSP- or PS-LTP in both groups of slices. However, TPS delivered in the presence of long-term in vitro morphine caused the PS-LTP reversal. This effect was blocked by the adenosine A1 receptor (A1R) antagonist CPX (200 nM) and furthermore was enhanced by the adenosine deaminase (ADA) inhibitor EHNA (10 μM). Interestingly, TPS given 30 min after LTP induction in the presence of EHNA (10 μM) can reverse LTP in morphine-exposed control slices in vitro. Conclusion These results suggest adaptive changes in the hippocampus area CA1 in particular in adenosine system following repetitive systemic morphine. Chronic in vivo morphine increases A1R and reduces ADA activity in the hippocampus. Consequently, adenosine Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S105 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall can accumulate because of a stimulus train-induced activity pattern in CA1 area and takes the opportunity to work as an inhibitory neuromodulator and also to enable CA1 to cope with chronic morphine. In addition, adaptive mechanisms are differentially working in the dendrite layer rather than the somatic layer of hippocampal CA1. Keywords fEPSP; Sodium-Salicylate; Synaptic Modulation; Theta Pulse Use of the” Heat Shock” Method for the Better Separation and Detection of the Opiates (Morphine, Codeine, Etc.) Mohamad Sadeghi1, Ali Ajami 2, Sohrab Akbari3, Mohamadreza Beheshti4 1. Manager of Isfahan Ebn Sina Lab 2. Isfahan Medical and Health University 3. Isfahan Medical and Health University 4. Coworker Background and Aim At present the most laboratories diagnosis of substance abuse especially state centers exporter of Certificate non addiction ،use the rapid dipstick tests for initial screening of urine samples positive or negative. inasmuch as many of drugs produce various metabolites in the human body that for reason the structural similarity، interfere to opiates group and cause creation “false positive” in the Stage screening. and this while that for reasons as: legal ، job and family consequences, for a correct diagnosis use of a verification method such as test “TLC” is necessary.TLC (thin layer chromatography) is a method of chemical analysis where drugs based on differences in molecular weight and affinity for the two different environment moves onto a thin layer and then will separate from each other in a certain position. at present for final confirmation used from the” hexa chloro platinum” for staining and decryption opiates bands.This color because of having Halogen compounds Is a carcinogenic agent and very dangerous for the Staff user . So this method for several reasons as: lack of safety ، failure to identification weaker bands، Instability and etc..is a unreliable diagnosis and must be replaced to a better Method (as heat shock method). Methods In order to compare both of these method in laboratory ، urine samples were collected from the 80 patients that confess to use the opiates in different intervals times and doses and in TLC test was used from both methods (staining and heat shock) for final confirmation of opiates. Results in this survey we found that only some of the samples that had used of excessive substance was detectable by staining and other samples (despite ensure positivity) were acquitted by this method practically. And this while that in heat shock method almost all selected urine samples presence of morphine were confirmed. Conclusion In this Research that is a experimental - comparative study we find that heat shock method for Several reasons as : high safety for personnel , fast Recognition ,safe and easy separation , high stability, detection of weak bands morphine and etc.. have a preference than staining by “hexa chloro platinum” and this while that most local companies diagnostic kits manufacturer in his visits from the our laboratory admit the ability of heat shock method . Keywords False Positive, Morphine, TLC, Hexa Chloro Platinum, Heat Shock. Blockade of the Dopamine D1-like Receptor in the Nucleus Accumbens Attenuated Acute Food Deprivation-Induced Reinstatement of Morphine Seeking in Rats Fatemeh Sadeghzadeh1, Seyed Ali Sadegh Zadeh2, Vahab Babapour3, Abbas Haghparast4 1. Department of Basic Science, Tehran University of Veterinary Medicine, Tehran, Iran 2. Neuroscience Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran 3. Department of Basic Science, Tehran University of Veterinary Medicine, Tehran, Iran 4. Neuroscience Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran Background and Aim Dopamine is a predominant catecholamine neurotransmitter in the central nervous system, which plays an important role in both priming-and cue-induced reinstatement of extinguished drug seeking. In contrast, the role of dopamine in food deprivationinduced reinstatement of morphine is not clear. In this study, CPP paradigm was used to evaluate the effects of intra-accumbal (NAc) administration of SCH23390 as antagonist of dopamine D1 like- receptors on food deprivation induced reinstatement of morphine. Methods Adult male albino Wistar rats weighing 200-250 g were bilaterally implanted by a cannula into the NAc. During 3-day schedule of conditioning Subcutaneous (s.c.) administration of morphine sulphate (5 mg/kg) produced CPP. Conditioning score and locomotor activity were recorded by Ethovision software. Following acquisition of CPP animals were placed in CPP box and the time spent in each compartment was recorded by Ethovision each day. This procedure was repeated for each animal in control and experimental groups until the calculated conditioning score (CPP scores) in two consecutive days in extinction period became similar to those on the pre-conditioning day. On the last day of extinction the rats were given bilateral injection of different dose of SCH23390 (0.25, 1 and 4 µg/0.5 µl/side or saline 0.5 µl) in the home cage. In the next set of experiment, the rats were subsequently tested for reinstatement after acute (24 h) food deprivation. Results Results indicated that food deprivation induced reinstatement of morphine and the dopamine D1-like receptor antagonist dosedependently attenuated food deprivation-induced reinstatement. Conclusion It is concluded that acute food deprivation-induced reinstate- S106 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall ment may be mediated, at least in some way, by activation of the dopamine D1-like receptor in the nucleus accumbens Keywords Dopamine D1-like Receptor ,Nucleus Accumbens ,Food Deprivation, Addiction, Reinstatement In vivo Evaluation of Methamphetamine Effects on Protein Carbonyl, Total Antioxidant Capacity and Malondealdehyde Levels as Oxidative Stress Markers. Faezeh Sadrabadi Haghighi1, Alireza Hosseinzadeh2, Mohammad Hossein Tanipour3, Mostafa Akhlaghi bagherjeri4, Mohammad soukhtanloo5, Seyed Isaac Hashemeyi6 1. .Department of Medical Biochemistry, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran 2. Department of Biology,Faculty of Science,Science and Research Brench of Islamic Azad University of Kordistan,Iran 3. Department of Medical Biochemistry, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran 4. Department of Medical Biochemistry, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran 5. Department of Medical Biochemistry, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran 6. Department of Medical Biochemistry, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran Protein carbonyl level increased proportionally with dose raising especially in 7.5mg/kg in chronic group but this levels of protein carbonyl didn’t show significant difference. Similarly In case of MDA the long time periods without focus on different doses showed the prominent result but the level of MDA by increasing the treatment time had a descending trend. The TAC level in serum didn’t have any different amount in groups concerning neither time period nor doses. Conclusion In previous researches, It is proved that amphetamine family (“the Glass”) can lead to elevation of oxidative stress markers such as protein carbonyl,malondealdehyde and Total Antioxidant Capacity .Our results showed that these markers changed with increasing in time and dose. For instance protein carbonyl level increased in 7.5mg/kg and in chronic group. Unlike our expectation about serum levels of TAC and MDA, our results did not show a significant difference between treated groups and control groups. Surprisingly the MDA level had a decreasing slope by time. It seems that in our study condition, METH did not have worthy effect on oxidative stress markers. We suggest using of more samples and various doses in next studies to obtain more confident results. Keywords Methamphetamine,Protein Carbonyl,MDA,TAC Background and Aim Methamphetamine is one of the most toxic of the drugs of abuse. Prevalence of the “glass” (The street name of methamphetamine) abuse is a serious problem in IRAN that menace health and security of social life. Physiologic and biochemical effects of its abuse besides mental effects are the concern of researches. We aimed to evaluate the relationship between methamphetamine and the most important oxidative stress marker including protein carbonyl,malon dealdehyde(MDA) and Total Antioxidant Capacity(TAC). Methods Results Methamphetamine was supplied by Khorasan Razavi Drug Control Coordinating Council. This research was carried out on the effects of methamphetamine on rats in 15 groups involved 5 doses (0,2.5,5,7.5,10 mg/kg) and 3 time periods (3 days,14 days and 40 days).After these periods rats blood were obtained and serum was separated by centrifuging. All experiments were carried out on serums. DNPH reaction was utilized to measure the protein carbonyl content in samples by using Cayman Kit(Item No.10005020).The amount of protein-hydrozone produced is quantified spectrophotometrically at an absorbance between 360385 nm. Cayman kit(Item No.10009055) was used to measure TBARS(MDA).The MDA-TBA adduct formed by the reaction of MDA and TBA under high temperature(90-100°C) and acidic conditions is measured colorimetrically at 530-540 nm.Similarly,The Cayman’s Antioxidant Assay(Item No.709901) was used to measure the total antioxidant capacity.The assay relies on the ability of antioxidant in the sample to inhibit the oxidation of ABTS to ABTS+ by metmyoglobin.The amount of ABTS+ produced can be monitored by reading the absorbance of 750nm or 405nm. The Relationship between Executive Functions and Mindfulness in Opiate Dependence and Abstinence Addicts Saber Saeedpoor1, Farshid Alipoor2 1. University of Kharazmi Tehran 2. University of Kharazmi Tehran Background and Aim The aim of this research was to investigate the relationship between Executive Functions and mindfulness in opiate dependence and abstinence addicts Methods 40 addicts with sampling accessible selected and completed a Five Factor Mindfulness Questionnaire and were evaluated Wisconsin card sorting and Tower of London Results results revealed that there was a positive relationship between Executive Functions and mindfulness in opiate dependence and abstinence addicts. The finding revealed group abstinence addicts scored higher in Five Factor Mindfulness Questionnaire and better performance in the Tower of London and Wisconsin card sorting Conclusion As a result, there were more deficits in the executive functions and mindfulness of opiate dependence group in comparison to the abstinence addicts group. This can help to choose an appropriate treatment substance abuse Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S107 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Keywords Executive Functions, Mindfulness, Opiate Dependence From Crying for a Candy to Begging for Drug: Investigating the relationship among Low Frustration Tolerance, Negative Affect and Drug Abuse Mahsa Samee Fard 1, Javad Salehi Fadardi2 1. M.Sc. in General Psychology, Department of Psychology, Faculty of Education and Psychology, Ferdowsi University of Mashhad 2. Associate Professor, Department of Psychology, Faculty of Education and Psychology, Ferdowsi University of Mashhad Background and Aim Many theories have clarified the relationship among low Frustration Tolerance (LFT), negative affect and drug abuse. Low Frustration Tolerance, disability to overcome negative affect and its emotional disturbance may stimulate the person to abuse in turn the frustration level will lower and result in ultra-sensitivity to surrounding stimulant; the cycle in which the impulsive behaviors will be intensified. However, previous research didn’t use from the specialized tools to measure the frustration tolerance, particularly in implicit level. Also, these studies considered frustration as a manifestation of negative mood, and didn’t review the role of frustration alone. In the current research, we investigate the frustration tolerance in the two level of self-reported and implicit. Also, we examined the role of negative affect as a mediator in the relationship between frustration and drug temptation. Methods Drug abusers (n=70) and non-abusers (n=70) completed the Discomfort-Frustration Scale (FDS), Drug abuse Temptation questionnaire (drug abusers only), Positive and Negative Affect Schedule, and computerized interpretation bias assessment task. FDS measured self-reported frustration, and computerized interpretation bias assessment task assessed implicit frustration. In order to confirm the replicability of the results, the self-reported part of the study was repeated on 62 new drug abusers and 62 new non-abusers. 29 of abusers who scored high in FDS and Drug abuse Temptation questionnaire, Positive and Negative Affect Schedule, and 29 of non-abusers who scored high in FDS and Positive and Negative Affect Schedule completed the computerized interpretation bias assessment task. Results Results showed that self-reported frustration tolerance level in drug abusers was significantly lower than non-abusers. This relationship was repeated in the replicability study. Furthermore, implicit frustration tolerance level in drug abusers was significantly lower than non-abusers. The correlation was verified among the low frustration tolerance, negative affect and drug abuse.Moreover, the results showed that negative affect didn’t play a mediator role between frustration tolerance level and drug abuse temptation. Conclusion According to the results, the presence of low frustration tolerance and negative affect was confirmed among abusers. These conditions contribute to the development and maintenance of substance abuse. Besides, these findings highlight the importance of frustration tolerance level and also underline complementary studies in the field. Keywords Frustration Tolerance Level, Drug Abuse, Frustration-Discomfort Scale (FDS), Interpretation Bias Mental Health in Addicts Under Methadone Maintenance Therapy (MMT) Alireza Sargazi1, Mojtaba Ghalandarzadeh2, Zahra Sepehri3, Mohammadmahdi Sargazimoghaddam4, Ali Mohasebi5, Aliyeh Sargazi6, Morteza Salarzayi7, Abolfazl Mohammadi8, Fatemeh Sargazi9 1. Medical Student, Zabol University of Medical Sciences, Zabol, Iran 2. Medical Student, Zabol University of Medical Sciences, Zabol, Iran 3. Internist, Assistant Professor, Zabol University of Medical Sciences, Zabol, Iran 4. Medical Student, Zabol University of Medical Sciences, Zabol, Iran 5. Medical Student, Zabol University of Medical Sciences, Zabol, Iran 6. Medical Student, Zabol University of Medical Sciences, Zabol, Iran 7. Medical Student, Zabol University of Medical Sciences, Zabol, Iran 8. Public Health Student, Zabol University of Medical Sciences, Zabol, Iran 9. Medical Student, Zahedan University of Medical Sciences, Zahedan, Iran Background and Aim Globally, there are around 16 million illicit opioid users; 0.4% of the total population in the 15 to 64 age group. Of those, 11 million people abuse heroin, according to the 2007 World drug report. Opioids are naturally occurring opiates and synthetic and semi-synthetic drugs that act on opioid receptors in the brain and can cause dependance due to their euphoric effects. Heroin is an opioid. Other examples are morphine, methadone and buprenorphine, widely used as pain-killers. Mental health refers to a broad array of activities directly or indirectly related to the mental well-being component included in the WHO’s definition of health: “A state of complete physical, mental and social well-being, and not merely the absence of disease”. It is related to the promotion of well-being, the prevention of mental disorders, and the treatment and rehabilitation of people affected by mental disorders. The purpose of the present study was to surveys mental health of Addicts under Methadone Maintenance Therapy (MMT) Methods This is a cross – sectional study. Jackson mental health screening form III is used for data collection that included 17 questions. This questionnaire included 2 sections, in the first section, demographic questions were asked and in the second section mental health information was assessed. This questionnaire conducted among 80 addicted persons that are under treatment with methadone in Zabol addiction treatment clinics by census sectional method and then data analysis with descriptive statistics. Results From the 80 Addicts under Methadone Maintenance Therapy that are studying by mental health questionnaire, 72.7 were male, 27.3 were female. Our study results indicate that mental health of 18.2% of addicts is good, 45.5% are moderate and 36.4% have considerable mental problems. Also there is no considerable relation between sexuality and mental health. S108 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Conclusion According to the results, considerable rate of Addicts under Methadone Maintenance Therapy are involving with mental problems which can be create some problems in personal life and social relations, So treating by a psychologist is recommended for this people. Keywords Mental health, Addicts, Methadone Maintenance Therapy (MMT) Effectiveness of Life Skills Training on the Reduction of Addicts’ Psychological Distress to Narcotics Mostafa Sekhavat1, Rahimiyanpour, L2 1. Dezful University of Medical Sciences and Health Services 2. Islamic Azad University, Sciences and Research Branch, West Azerbaejan Objective: the present research aimed to examine the effectiveness of stress management with behavioral – cognitive mode on impulsivity diminished of drug abusers who are under methadone maintenance treatment. Methods the research design in this study was quasi – experimental , 20 drug abusers who were under methadone maintenance treatment were selected by available sampling mode from one of the Tehran province clinic , then were put into two experimental group ( 10 individuals ) and control group ( 10 individuals ).The stress management with behavioral – cognitive mode has been educated in 10 sessions for experimental group, and Barratt Impulsivity Scale (BIS), in first , the end and two month after education were completed by participants. Results Background and Aim Life skills training programs are among applications of psychology in different individual and social arena organized with the aim of promoting physical and mental health and preventing psychological, physical and social damages. The purpose of this study was to examine the effect of life skills training on the reduction of Addicts’ psychological distress to Narcotics. Methods The population included all addicts referring to Dezful self-report centers. The sample included 40 who were selected by simple random sampling method and were assigned to two experimental and control groups. The instruments used in this study include Depression, Anxiety and Stress Scales (DASS-21) and life skills training guide. The design of the study was pre-test/post-test with a control group. After random selection of experimental and control groups, the pre-test was conducted on two groups, then the experimental intervention (life skills training) was performed and after completing the training program, the post-test was administered to both groups. To analyze data, multivariate covariance analysis method was used. Results The results show that life skills training reduce psychological distress the experimental group compared to the control group. Conclusion The results of this study indicated that the life skills training can reduce the addicts’ psychological distress to narcotics. Keywords Life Skills, Psychological Distress, Addicts’ Narcotics The Effectiveness of Stress Management with Behavioral – Cognitive Mode on Impulsiveness Reduction of Drug Abusers who are Under Methadone Maintenance Reatment Zahra Sepehrinasab1 1. Allame Tabatabaee Background and Aim The results of covariance analysis showed that, experimental group scores mean in total and motor impulsivity subscale compared to control group there were significant decrease, but between scores mean of experimental and control group in attention and non- planning impulsivity subscales there werenʾt significant difference. Conclusion The results of this study had shown that stress management education with behavioral – cognitive mode can be an effective mode for drug abusers who are under methadone maintenance treatment. Keywords Stress Management , Impulsivity, Drug abuse. NA and Social Morality in Drug Rehabilitation Ziya Hashemi 1, Maryam Shaban2 1. Hashemi 2. Shaban Background and Aim The growing problem of addiction is ringing the bells for families. Drug addiction as a disaster leads to the deviation of moral and cultural values and norms and endangers social health. The current research entitled NA and Social Morality in Drug Rehabilitation is seeking efficiency of moral-based approaches in drug rehabilitation. In this regard the theories of Durkheim, Merton, Howard Becker and Harry Triandis in the fields of deviances, addiction, social morality and collectivism have been used Methods The population of study consists of 4700 persons taken part in NA meetings held in the city of Boroujerd and they were categorized in 23 groups (male and female). The qualitative research method has been used and tried to investigate the training programs presented in NA meetings by content analysis technique in three levels of Traditional, Step and Concept by focusing on social morality and collectivism. In addition, depth interview technique was used to measure the changes in moral tendencies and their improvement trends. Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S109 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Results Final results shows the existence of un-ideological and moralbased approaches in three steps NA programs and also their positive influence of these programs on reinforcing the patients moral mind in drug rehabilitation and health recovery. Conclusion Final results shows the existence of un-ideological and moralbased approaches in three steps NA programs and also their positive influence of these programs on reinforcing the patients moral mind in drug rehabilitation and health recovery. Keywords NA Anonymous Addiction Association, Drug Rehabilitation, Social Morality, Collectivism, Individualism The Need for Gender Responsive Social Support Programs Jaleh Shaditalab1, Sonia Ghafari2, Molouk Azizzadeh3, Laila Khanjaninejad4 1. Prof.TUNiversity of Tehran 2. Reseacher 3. Researcher 4. Researcher Background and Aim In recent decade it is acknowledged that the root of HIV infection diffusion is gradually moving from male injecting drug users to their sexual partners. As the result drug treatment programs have turned to female population; mostly as residual to drug programs. Now we are learning that there are challenges and issues specific to women’s vulnerability; gender norms, socio-cultural factors, fewer resources, drug as coping mechanism for physical and psychological problems, different reasons for relapses,…. Assessment studies conducted on female drug users’ report some common needs but different priorities which are mostly shaped by structural ad socio-cultural factors in each society. In responding to gender issues in drug treatment programs ,experiences proves that different stakeholders take responsibility; health care providers, police, housing corporations, justice department, 24 hours emergency services, night shelters, training and education centers, health insurance and social benefit agencies. The aim of present article is to provide information on FDU’s (Female Drug User) needs for social supports from both FDUs and service providers’ perspective. Hopefully it would help to recognize the importance and criteria for development of gender responsive support programs in Iran. Methods information gathered through 48 semi-structured interviews with service providers and FDUs seeking treatment and supports by entering 3 types of institutions in Tehran in 2011: Khaneh Khorshid; drug substitution treatment (south), Chitgar Camp ; residential abstinence (West) and Congress 60 out-patient abstinence treatment (Center of the city). Results Findings on needed social supports show two distinct groups among FDUs; higher and the lower socio-economic and there are discrepancies on their need for social supports. While higher socio-economic group believe; when they get over drug use they and their family are able to support them, the Lower socio-economic group could not comprehend the question on “their needs for social supports”. With more explanation, we had two different sets of responses: (a)”whatever we have and we receive from DIC is very good and enough” (b) “We need a room (a place to live) and income (work)”. A list of 9 most important supports based on literature, and previous interviews was prepared and questioned. The responses were in this order: 1) Employment and income, 2) housing, vocational training and 3) health (physical and psychological). Only two FDUs mentioned education and nobody mentioned the need of legal assistance, protection against violence and child care. Regarding the cooperation of stakeholders the very least was observed. Service providers emphasizing the importance of social supports for FDUs acknowledged that they are not able to provide the needed supports. Conclusion Delivering only one service cannot be a stand-alone strategy; we need engagement of different organizations for FDUs recovery and reintegration and overcoming structural barriers in providing gender responsive social supports. Any program should integrate social supports of education, legal assistance, childcare, violence protection and the most important supports for them; economic (employment, vocational training & income generation) and housing (shelter and transitional accommodation) and health. Keywords Women, Drug Use, Social Support The Examining of Replicable the Model for the Relationship between Families’ Mental Health and Prediction of Substance Abuse Farhad Shafiepoor1, .Farhad Shafiepour Motlagh2, Monireh Torabi Nahad3 1. Department of Educational Administration, Mahallat Branch, Islamic Azad University, Mahallat, IRAN 2. Department of Educational Administration, Mahallat Branch, Islamic Azad University, Mahallat, IRAN 3. Department of Educational Administration, Marand Branch, Islamic Azad University, Marand, IRAN Background and Aim Examining of Replicable the Model for the Relationship between Families’Mental health and prediction of substance abuse Methods The methodology of this research was correlation. Statistical community included all of Mahallat Branchs’ students. The way of sampling was due to percent of educational groups that selected (n=220) students randomly. the data were gathered by two questionnaires: 1. Families’ Mental health(=α 0.89),2. Prediction of substance abuse (=α 0.93). The data of the research analyzed by step by step regression and SEM Results The total findings revealed that families’ internal and external S110 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall mental health influence on substance abuse( P<0.05).Also the findings revealed that prediction of substance abuse influence on families’ internal and external mental health (P<0.05 ).finally there were interactional relationship between families’ internal and external mental health and substance abuse(P<0.05). greater side effects on cognitive performance, cognitive functioning can fluctuate as a function of both time since last dose and treatment duration Keywords Methadone Maintenance, Methadone Dose, Cognitive Impairment Conclusion when the families have internal and external mental health, they avoid from substance abuse. Also avoiding from substance abuse results to families’ mental health and no problems for families such as divorce, depress,...). However, the variables of this research have interactional relationship. Keywords Families’ Mental Health, Prediction of Substance Abuse, Students Cognitive Impairments in Methadone Maintained Patients as a Function of Dose, Time Since Dosing and Treatment Duration Zeynab Shahabazi1, Usha Barahmand2, Zeynab Shahbazi3, Ali Khazaee4 1. Young Researchers and Elite Club, Ardabil Branch, Islamic Azad University, Ardabil, Iran 2. Associate Professor, University of Mohaghegh Ardabili 3. Young Researchers and Elite Club, Ardabil Branch, Islamic Azad University, Ardabil, Iran 4. University of Mohaghegh Ardabili Background and Aim Methadone maintenance treatment is a standard evidence-based treatment for opiate-dependent individuals. However, there have been many reports suggesting that this treatment is associated with cognitive impairments as side-effects. Aim: The present study compared the cognitive performance of methadone maintained patients Methods A sample of 53 methadone maintained patients, divided into two groups. One group (25 patients) was assessed 90 minutes to 3 hours after methadone administration, while the other group (26 patients) was assessed just before methadone administration, that is, 24 hours after the last dose. Tests on cognitive flexibility, working memory, psychomotor speed, response inhibition, decision making and emotion perception were administered. All patients were pure opioid addicts and were in methadone maintenance treatment for a period of 6 months to 3 years. Results Findings revealed that the two groups differed significantly only on decision making. That is, decision making was poorer during peak sessions than during trough states. In other words, as time since last dosing increased, methadone maintained patients made better and more safe decisions. Higher doses were associated with deficits in cognitive flexibility, working memory and response inhibition. The effects of treatment duration were mixed, with longer treatment resulting in worse performance on working memory, improved performance on emotion perception and no effects on psychomotor speed Efficacy of Trainings Healthy Lifestyle Based on the WHO Model on Resiliency, and Life Satisfaction in Women with Addiction Husbands. Maryam Shahbazi1 1. MD. Clinical Psychololgy. Allameh Tabatabai University Background and Aim Introduction: Drug addiction is one of the most important social problems that cause will be the disintegration of societies and loving families, divorce, suicide and other social and psychological damage. Healthy Life Style Training is learning the proper solutions to mitigate the effects of disasters and the impact of health on quality of life in the four components of physical health, mental health, social health and spiritual. Purpose: The purpose of the following research is to study the effect of Healthy Life Style Training based on the World Health Model on resiliency, and life satisfaction in women with addiction husbands . Methods The population of this research includes all the women with addiction husbands in Ivan at year 1393. Sample of the research includes 30 of the population who were chosen through convenience sampling (15 as experimental group and 15 as control group). Conner and Davidson resiliency scale and Denier’s Life Satisfaction questionnaire are the assessment tools which were used in this research. Both groups were given pre- tests before the training. Then the experimental group was trained Healthy Life Style for 7 sessions, each session lasting for 90 minutes and the control group did not receive any interventions. Right away after finishing the training sessions, both groups were given post-tests. The analyze was done with use of a Descriptive Statistics including mean, standard deviation and inferential statistics including covariance analysis . Results The result showed (pre-test and post-test) within the 2 groups by 95% of confidence confirms the efficiency of the Healthy Life Style Training on the women resiliency, and life satisfaction. Conclusion Due to family members, especially spouses can support their healthy spouses are encouraged to try to quit drugs.Given the focus on women’s health as an important supportive family is essential Keywords Healthy Life Style, WHO, Resiliency, Life Satisfaction Conclusion The results suggest that while higher doses of methadone have Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S111 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall The Comparison of Sensation seeking and power of risk-taking in adolescent smokers and non-smokers. Maryam Shahbazi 1. MD. Clinical Psychololgy. Allameh Tabatabai University 1 Background and Aim Introduction: Adolescence is a critical developmental period that is associated with the process of identity formation. A Part of this process is to save the growing risk of unhealthy behaviors, alcohol use, smoking, and other materials may be present. purpose: The aim of this study was therefore the compare of sensation seeking and the power of risk-taking in adolescent smokers and nonsmokers . Methods The population of this research includes all the adolescent smokers and non-smokers in Ivan at year 1393. Sample of the research includes100 members of the population who were chosen through (n = 50 per group) the convenience sampling method. The assessment tools which were used in this research are Zuckerman sensation seeking questionnaire and Reza-Khan power of risk Scale . For the data analysis, descriptive statistics, including mean and standard deviation and inferential statistics were used in the Tindependent. Results The results showed there were significant differences at 0/05 level between groups. Conclusion The results of the data analysis showed were differences in power of risk-taking and sensation seeking adolescent smokers and nonsmokers in the extreme. Attention to the emotions of adolescent and encourage them to apply for the outflow of the healthy aspects need to be. Keywords Sensation Seeking, Risk-Taking, Adolescent Demographic and High Risk Behavior Profile of Substance Abusing Women Inmates in Iranian Prisons Background and Aim 2 3 Methods With a grounded theory design, the present cross-sectional study was designed and conducted in 2012 in Iran. The study population included 694 women inmates in 5 random selected prisons with more than 100 inmates. Our data collected using questionnaires filled in by trained interviewers. Regarding to illicit drug use, data was divided to four groups: inmates who have 1) Only opioid use, 2) Only stimulant use, 3) Opioid and stimulants use, 4) Without history of drug use. Data was analyzed by SPSS 21 Results The mean age of inmates in the study was 34.1 (CI95%: 33.234.3) and the average age of starting using drugs such as opium, heroin, crack and methamphetamine respectfully was 22.3 (21.223.5), 23.5 (22.2-24.7), 25.4 (23.8-26.9) and 25.6 (24.6-26.6). 11.5% of inmates just had history of opioid use, 8.5% just stimulant use, 26.2% both opioid and stimulants. Regarding to educational level they divided level into three groups: unlettered, under diploma and academic education, the percentage of each groups were respectfully 33.8-66.3-0.0 in opioid users, 13.3-73.3-13.3 in stimulant users, 12.6-78.6-8.8 in multi drug users and 18.571.5-9.9 in no drug users. This research was shown 71% of drug abusers had history of sex with Non-spouse and the prevalence of non-condom using in drug users was 2.8 times more than no drug users. This rate in concurrent drug users was 4.8 Sex with non- spouse was 12.7(69% non- condom use) in opioid users, 28.3 (30% non- condom use) in stimulant users, 42.6 (72% noncondom use) in multi drug users and 11.6 (65% non- condom use) in no drug users. Conclusion According to the research, the pattern of drug abuse and condom use in sexual activities has changed with higher education level. It seems that drug-users had more sexual relationship with nonspouse and high risk behaviors Therefore proper training methods with safer alternatives to high-risk behaviors, harm reduction programs and drug treatment are necessary for women inmates iside prisons and after released. Keywords Women, Prison, Addiction, Harm Reduction Mohammad Shahbazi , Marzieh Farnia , Zahra Vaezi , Amin Setarehdan 1. GFATM-UNDP project in Prisons Organization 2. Prisons Organization 3. GFATM-UNDP project in Prisons Organization 4. Prisons Organization 1 gard to drug-using and can be considered in any plan for harm reduction programs among addict women. 4 At the end of 2013, there were almost 7,800 imprisoned women in Iranian prisons and although they make up less than 4% of the prison population, regarding to their high risk behavior, they do act as a bridge to transfer the blood-born infections to the whole community. The aim of this abstract was to study demographic and high risk behavioral profile of women inmates in Iran in re- To Implement an Innovative Method of Peer Education in Iranian Prisons to Improve Inmates’ Knowledge on Harm Reduction Mohammad Shahbazi1, Marzieh Farnia2, Mohammad Reza Keramati3 1. GFATM-UNDP Project in Prisons Organization 2. Prisons Organization 3. Emam Khomeni Hospital Background and Aim CANDIDATE FOR PREVENTIVE AWARD OF WELFARE ORGANIZATION Weakness of knowledge of prisoners on drug S112 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall abuse and high risk behavior is a critical problem all across the world and it is not limited to a country or an especial society. Peer Education Program(PEP) is one of important harm reduction programs in prisons for providing information to change behavioral patterns. In this method members of the target group are selected and trained to transfer key information to their peers through face to face training or small group discussions. Peer education is a behavioral change strategy that has a known theoretical basis. Methods Fission Model of Peer Education (FMP)for incarcerated inmates: Each inmate was first educated by designated health professionals on harm reduction issues then requested to educate three other inmates with the assistance of pamphlets. Each of these three inmates in turn trained three more inmates, and the process continued in a spontaneous tree manner. In each prison block, the initial training was just given to the one or two first-level inmate(s) and the knowledge passed on to the next levels spontaneously. The feedback was then retrieved by means of questionnaires attached to the educational pamphlets to be filled by the inmates. The goal of educating two leader inmates was to create two networks in a competitive atmosphere. The information was recorded and analyzed using a special software program designed for this purpose, and participating inmates were ranked in four levels and rewarded (financial and non-financial such as family visits, leaves and ...awards) according to the number of inmates they educated. The financial award has been delivered to inmates’ bank accounts. The level of award has been determined by software, therefore intervention of personnel in the above processes was limited. Results This protocol were developed over a period of two years and implemented in a six-month pilot in prisons in 2010-2011. Then it has implemented in 17 prisons for 24 months up to end of March 2014, Now the program is running in 28 prisons with population more than 1000 and trained more than 128,515 inmates. The educational topics were Methamphetamine, harm reduction, HIV/AIDS issues. Pre-test, post-test study was performed in 2 sites of program in November 2012 (unpublished study), the univariate analysis indicated that the knowledge of prisoners participating in PEP increased dramatically (p<0.0001). Conclusion The goal of the above models was to install a spontaneous, ongoing educational system with a competitive environment, and we seem to have been successful in achieving this goal. On the other hand, the M&E system of the protocols improved the efficacy of the process. Keywords Drugs, Prisons, Peer Education Network Location as the Main Predictor of HIV Transmission Risk in Injecting Drug Users: Results from Multiple Membership Multilevel Modeling of Social Network. Armita Shahesmaeili1, Hamid Soori2, Ali Akbar Haghdoost3 1. Depertment of Epidemiology, School of Public Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran 2. Depertment of Epidemiology, School of Public Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran 3. Regional knowledge Hub, and WHO collaborating centre for HIV surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran. Background and Aim Injecting drug users (IDU) are the key group contributed to HIV transmission in Iran. Despite the large-scale coverage of harm reduction program, some IDU continue to engage in high risk behaviors. It seems that there are some Macro/Social-level factors that contribute to risk of HIV transmission in IDU. The aims of present study was to analysis the social network of IDU and examine the adjusted effect of network location on HIV transmission risk using the multiple membership multilevel model. Methods From October 2013 to March 2014 we conducted face-to-face interviews on 147 IDU . We asked participants to nominate up to 20 people whom they had more than causal contact with them during the past 30 days and specify if each nominee is drug injector or not. We defined four locations based on component and K-core analysis of sociometric network including: Core of main component, Peripheries of main components, members of other small components, isolates / unlinked. The risk of HIV transmission for each individual was measures based on 7 item scale that we constructed by Principal Component Analysis. We applied Multiple Membership Multilevel Linear Regression analysis to examine the relationship between network location and HIV transmission risk adjusted for other variables. Results The mean age of participants was 37± 9.32.Most of individuals were male (91%) single (50.1%) and educated up to guidance school (73.5%). Most of participants experienced the first occasion of injection before the age of 30(66.7%) and declared the “friendship with an IDU” as the prominent cause of The mean age of participants was 37± 9.32.Most of individuals were male (91%) single (50.1%) and educated up to guidance school (73.5%).Being a core member of main component as like as being a member of other small components in comparison with Isolates/unlinked significantly increase the HIV Transmission risk. IDU who are not under the Methadone Maintenance Therapy (MMT) compared to IDU who engage in MMT have an increased risk of HIV transmission. Conclusion Network analysis can act as a useful guide to find the core or most influential members of IDU network. This subpopulation may act as key individuals in the transmission of HIV to other IDU as like as bridging population Furthermore it provides the harm reduction staff to find the broader number of IDU who are usually hard to reach by routine outreach case-finding tasks. The efficacy of interventions programs among IDU can be reinforced by addressing them to more influential individuals within the network. Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S113 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Keywords Social Network Analysis, Injecting Drug Users, HIV Transmission Risk, Iran Predictive Role of Religious Orientation in Reducing Suicidal Ideation and Vulnerability to Stress in Subjects Treated with Methadone and Ordinary People in Khorramabad Mohammad Shahkarami1, Sirous Moradi Zadeh2, Somaye Abassi3, Mina Papi4, Nahid Hadavi5 1. M.A in Family Therapy in Kharazmi University of Tehran 2. M.A in Phychology 3. M.A in Family Therapy 4. M.S in Psychology 5. M.A in Psychology Oloum Tahghighat University of Boroujerd Background and Aim addicted patients treated with numerous psychological problems buckle that can affect their health, the goal of the research is the role of the religious orientation in reducing suicidal ideation and vulnerability to stress in individuals methadone treatment and normal individuals is Khorramabad. Methods The following research is descriptive and correlation between the availability of methadone treatment, 91 individuals were selected. After completing the questionnaire, religious orientation, Allport (1986) and Beck and Beck questionnaire of 19 questions about suicidal thoughts Varan vulnerability to stress and Tal (1997), data were analyzed by 18 spss software. Results The results showed that there is a negative relationship between religiosity and suicidal ideation between religion and vulnerability to stress is negatively related to the other hand, multiple regression analysis showed that the predictor variables, criterion variables significantly to the explanation Conclusion The results showed that with the increase of religious and spiritual orientation can reduce its vulnerability in the face of threats of suicide and mental health, including stress and depression, and took action. Keywords Religious Orientation, Suicidal Thoughts, Vulnerability to Stress Determining the Effectiveness of Social Skills Training on Drug Addiction Treatment in Mehr Tabriz Clinic Hossein Shahmohammadi1, Shahram Yaghooti Azar2, Mina Fakhri3 1. Yung Reaserchers Club Islamic Azad University Tabriz-Iran 2. General Psychologist MA 3. Educational Planning MA Background and Aim The aim of this research was determining the effectiveness of social skills training on the prognosis of the treatment of addiction. Methods The method of this experimental research is pretest &posttest with control group. The subjects were 22 patients with drug abuse disorders, they selected with convenience sampling among patients that referred to the clinic of Tabriz and were placed randomly in two groups: experimental (12 subjects) and control (n = 12). In the experimental group social skills training was provided for two-hour eight sessions and the control group just in a waiting list. The Subjects of both groups were evaluated by a self-assessment questionnaire that included questions regarding family relationships and employment status and also by the ACIS questionnaire and clinical examination to determining the rate of slip and recurrence. Data were analyzed by paired-samples T test, independent T test and Mann-Whitney U. Results After a month follow-up, communication and interaction skills increased in experimental group and in comparison with control group were significantly different. Conclusion Social skills training can be used as an appropriate method for enhancing communication and interaction skills in individuals with drug abuse disorders to be applied. Keywords Social Skills, Drug abuse The Effect of Prevention Program of Addiction on Self-Efficacy, Self-Esteem and Adolescent’s Awareness of Drug Abuse Hossein SHahmohammadi1, Shahram Yaghooti Azar2, Mina Fakhri3 1. Yung Reaserchers Club Islamic Azad University Tabriz-Iran. Educational Psychology MA 2. General Psychology MA 3. Educational Planning MA Background and Aim The present study was examined, the effect of a prevention program of addiction on self-efficacy, self-esteem and adolescent’s awareness of drug abuse. This program was included the ways to coping with stress and increasing assertiveness, also the methods of resisting peer pressure and presenting the correct information about drugs and drug abuse. Methods For this purpose, statistical sample was included 120 male students of high school in Tabriz that divided into two experimental and control groups. At first both of groups were assessed pretest and then the independent variable (training) was conducted. Data were analyzed by correlated T test and independent T test. Results At first correlated T test the mean of pretest and posttest of S114 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall groups was compared. The results indicated that the training program increased self-efficacy, self-esteem and awareness in the experimental group. In the second method with independent T test, mean differences between the two groups were compared. Conclusion The results indicated that program only reduces the tendency toward drug abuse in experimental group than the control group. However, there weren’t a significantly difference of self-efficacy, self-esteem and awareness between groups. Keywords Prevention of Addiction, Self-Efficacy, Self-esteem, Awareness, Adolescent Assessing the Effect of Stress Management Training on the Readiness for Addiction Treatment Among Hamadan Drug Abuse Treatment Centers, Based on Applying Health Belief Model Babak Moeini1, Seyed Mohammad Mehdi Hazavehei2, Reza Shahrabadi3, Javad Faradmal4, Saeed Dashti5 1. Social Determinants of Health Research Center & Department of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran 2. Research Center for Health Sciences & Department of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran 3. PhD student in Health Education and Health Promotion, Tehran University of Medical Sciences, Tehran, Iran (*Corresponding Author) 4. Assistant Professor, Department of Epidemiology and Biostatistics, school of Public Health, Hamadan University of Medical Sciences, Iran 5. PhD student in Health Education and Health Promotion,Yazd University of Medical Sciences, Yazd, Iran Background and Aim Phenomenon of drug abuse is one of the social crises that disrupt the cycle of society development. Of the factors affecting increasing readiness for addiction treatment in addicted persons is learning stress management methods. Considering the importance of education to promote readiness for addiction treatment, this study determined the effect of stress management training on the readiness for addiction treatment among Hamadan drug abuse treatment centers, based on applying Health Belief Model. Methods In this quasi-experimental study, 85 addicts from two drug abuse treatment centers assigned to intervention and control groups. The tool of gathering data was a questionnaire based on Health Belief Model (perceived severity, susceptibility, benefits, barriers, self-efficacy and cues to action), the readiness for addiction treatment, referral regular, use of stress management methods and demographic variables that reliability and validity was assessed and reported appropriate. The educational intervention included four educational sessions of 60 minutes. Applied only in the intervention group and one month after the four sessions, educational booklet was distributed as a reminder among intervention group. Two months after intervention, two groups were followed and data were analyzed by using SPSS16. Results There were not statistical significant differences in demographic factors in two groups. There were statistical significant differences before and after intervention in the intervention group compared with control group in mean scores constructs of the Health Belief Model (perceived severity, susceptibility, benefits, barriers, self-efficacy and cues to action), the readiness for addiction treatment, referral regular and use of stress management methods. (Pvalue=/05) Conclusion Findings showed that educational intervention based on HBM may be an effective method for promoting readiness for addiction treatment in addicts. Keywords Drug Abuse Treatment Centers, Readiness for Addiction Treatment, Stress Management, Health Belief Model. Studying the Effect of Hookah Smoke on Blood Parameters in Rats Exposed to Acute Esmat Shahriary1, Abdol Ali Khammari 2, Ebrahim Miri-Moghaddam3, Ramazan Mirzaei 4 1. Master of Science Health, Safety and Environment . Department of Health 2. Master of Science Health, Safety and Environment . Department of Health 3. Health Promotion Reserch Center, Zahedan University Of Medical Sciences, Zahedan 4. Health Promotion Reserch Center, Zahedan University Of Medical Sciences, Zahedan Background and Aim One of the most common means of smoking tobacco is Water Pipe; it’s called (Arghile or Narghile) in the Middle East countries. Various studies reveal that smoking can affect the blood parameters. Being exposed to hookah and cigarette smoke leads to facing a complex mixture of over 4000 chemicals, including some well-known carcinogenic. One of these toxic materials is carbon monoxide which enters into bloodstream through the lungs and combines with hemoglobin, and thus the numbers of hemoglobin, red blood cells and hematocrit are increased. Unfortunately, at present time, hookah use is increasing among girls and women. The aim of this study was survey of hookah smoke effect on white blood cells and red blood cells in rats. Methods In this experimental-laboratorial research, 20 rates of Albino race were randomly divided into control group and the group of acute receiving smoke hookah; and each group contained 10 rats. After one month, blood sampling was performed by heart bleed; afterwards, the amounts of white blood cells , red blood cells, hemoglobin, and Hematocrit were determined by using cell counter device. Finally, descriptive statistics such as central distribution indexes, frequency distribution tables, and statistical diagrams were utilized to describe data; and inferential statistics such as T- test was used to analyze the data. Results The results showed that the average number of white blood cells Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S115 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall in the acute group and in the control group were 5.17and 4.60 ( ×10 6 mm3 ) respectively (P = 0.54). The average number of red blood cells in the acute group was 9.37 and in the control group was 8.82 ( ×10 6 mm3 ) (P = 0.04). The average number of hemoglobin in the acute group and in the control group stood at 18.44 and 15.09( gr/dl) respectively (P = 0.00). The average number of Hematocrit was 56.61 for the acute group and 50.20 (%) for the control group (P = 0.03). Conclusion The results of this research manifests that the hookah smoke affect the blood parameters; and the smokers are subjected to several diseases as well as cancer. This can be prevented by proper planning; thus the risks of hookah smoking will be decreased. Keywords Hookah Smoke, Red Cells, White Cells, Hemoglobin, Hematocrit Study of Social Factors , Individual and Environmental Effects of the Phenomenon of Addiction in Ilam City. Jafar Sharafkhani1, Ziba Mirhousainy2 1. PhD in Sociology, Univercity of Bakhtar in Ilam, Iran 2. Master of Scicology Background and Aim The purpose of this study, which was conducted in 1392 to investigate the social factors affecting personal and environmental trends to the phenomenon of drug addiction in Ilam city Methods The method used in this research has been the case study. The author has designed a questionnaire to collected data.The study population is 270 subjects who have been in prison at least once and data is obtained through the General Directorate of Prisons Ilam province. Based on the data obtaining through questionnaire, addiction intensity compare with each independent variables (severe aggression,depression, attitude to drugs, dropout, associate with bad friends, drug availability, unemployment) that causes social, environment and individual tendency to addiction is examined. Frequency of the Pearsontest showed that these variables have a significant affected of the addiction intensity variables. Results At descriptive level we used of frequency, density, averaging, averaging standard deviation and variance parameters. And inferential level, Pearson correlation, T-test and the contribution of independent variables to explain the dependent variable, the multiple regression and variance (ANOVA) was used.Addiction intensity is as integrated dependent variable that contains a combination quality and type of drug used and the frequency and method.In this research studied relationship with independent variables such as “severe aggression,” “attitude to drugs”, “depression”,”contacts with bad friends”, “drop out”, “availability of drugs”, “unemployment” examined is taken Conclusion The result indicates that there is a significant direct correlation between addiction intensity and aggression, attitude of drugs, associated with bad friends, depression, drug availability, and unemployment but showed a significant inverse relationship between leaving educationswith highly addictive. Keywords Addiction Intensity, Aggression, Depression, leaving Education, Drug’s Quality, Unemployment Prevalence of Crystal Meth and Ecstasy Users among 19-to 29-Year-Old Group in Iran: Findings of a National Cross-Sectional Survey Ali Ahmad Rafie-Rad1, Hamid Sharifi2, Ali Akbar Haghdoost3, Abbas Sedaghat4, Maryam Sargolzaei Moghadam5, Mohammad Mehdi Gouya6, Mohammad Karamouzian7, Samira Hosseini Hooshyar8, Marzieh Mohammadi9 1. PhD. Student of Cultural Sociology, Allameh Tabatabaei University, Tehran, Iran &Regional Knowledge Hub, and WHO Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran 2. Regional Knowledge Hub, and WHO Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran 3. Regional Knowledge Hub, and WHO Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran 4. Center for Disease Control, Ministry of Health and Medical Education, Tehran, Iran 5. Center for Disease Control, Ministry of Health and Medical Education, Tehran, Iran 6. Center for Disease Control, Ministry of Health and Medical Education, Tehran, Iran 7. Regional Knowledge Hub, and WHO Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran. 8. Regional Knowledge Hub, and WHO Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran 9. MSc Student of Social Research, AL-Zahra University, Tehran, Iran Background and Aim Crystal meth and ecstasy use has raised rapidly in Iran in the past few years. This increased popularity is mostly seen among the younger population, probably due to the feelings attributed to the use of these substances such as high energy, lack of fatigue, alertness, increased sexual desire, increased feelings of joy, power, and high self-esteem. Although these substances have been in the Iranian market for a while, the size and characteristics of their users are poorly understood. This study tries to estimate the size of crystal meth and ecstasy users in Iran; an information that is essential for policy makers and healthcare providers. Methods The present study was a sub-study of a national survey conducted on a representative sample of 3246 Iranian adolescents and youths (aged 19-29) in 13 provinces. Using a standardized pretested structured questionnaire, data was collected on participants’ history of crystal meth and ecstasy use. They were also asked if they knew any crystal meth or ecstasy user. Knowing someone was defined as “recognizing each other by sign or name S116 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall and having had contacted within the past year either in person, phone or email”. Data was analyzed using frequency and probability approaches. Results Based on our findings, 5.7% and 3.6% of the participants had a history of crystal meth and ecstasy use, respectively. Moreover, 30.1% of the respondents knew at least one crystal meth user. Around 34.9% of participants knew one, 24.3% knew two, and 14.5% knew three individuals as crystal users. On the other hand, while 10.1% of the participants knew at least one ecstasy user, 33.3% of them reported to know one, 26.3% knew two, and 12.8% knew three ecstasy users. Conclusion Although this self-reported data is subject to an underestimation of the size of crystal meth and ecstasy users in our sample, our findings reveal a considerable size of young people with a history of crystal meth and ecstasy use. Prevention programs should target this critical age group with proper educations regarding the emerging synthetic substances. Keywords Crystal Methamphetamine, Ecstasy, Youth, Survey, Iran. This study indicated that the majority of our understudy subjects had a history of previous attempts to treat their addiction with a maximum abstinence period of 6 months Keywords Treatment, Rehabilitation, Centers Relationship between Resiliency and Psychological Hardiness with Tendency to Substance Use in High School Students Maryam Sharifi1, Jamal Sourah2 1. Consultant, University of Applied Science and Technology, Bookan, Iran 2. University of Ardabil Background and Aim This study was carried out to assess the relationship of psychological hardiness and resiliency with the tendency to substance use in high school students’ areas of Bookan, Urmia, khoye, Makoo, Mohabad and Salmas. Also, to determine the contribution of each of the predicting variables Methods Common Methods to Treat Addiction Used by Patients Checked into Treatment- Rehabilitation Centers in Tehran Hooman Sharifi1, Mohammad Reza Masjedi2, Sepideh Sigari3 1. Tobacco Prevention and Control Research Center (TPCRC) 2. Tobacco Prevention and Control Research Center (TPCRC) 3. Tobacco Prevention and Control Research Center (TPCRC) This research is a descriptive -correlation study. A group of 450 high school students (225 girls and 225 boys from schools) were selected through cluster sampling method for this research. Measuring instruments were Ahvaz Hardiness Inventory (AHI), Connor- Davidson Resilience (CD-RIS) and tendency to substance use Inventory. Data was analyzed using, Pearson correlation coefficient and Stepwise multiple regression analysis. Results Background and Aim This study was to determine common methods to treat addiction used by patients checked into Outpatient Treatment and Rehabilitation Clinics in Tehran. Methods This study was conducted in Social Security affiliated outpatient clinics including 3 governmental and several private centers in 22 districts of Tehran. Demographic data, personal information, social characteristics and information regarding prevention, treatment and follow-up records of 1,372 patients were obtained and analyzed. Results Conclusion Our findings showed that a significant majority of cases referring to the treatment centers were males (95.2%). Patients were 14 to 75 yrs. of age (mean 35.48 ± 10.57 years); 61.7% were married and lived in rented homes in the city; 938/1372 (68.4%) had at least one previous attempt failure when seeking re-treatment. A significant majority of them (77.8%) had a history of 1 to 4 quit attempts; a significant number 63.1% had an abstinence period of 1 week to 6 months. The results showed that psychological hardiness (r=0 .34) is positively related to resilience (P<0.000). Psychological hardiness (r=-0.35) and resilience (r=-0.33) are negatively related to tendency to substance use (P<0.000). Also, the results showed that hardiness and resiliency are able to predict tendency to substance use significantly (P<0.000). Conclusion The findings indicate that hardiness and resiliency are important in the predictiing of tendency to substance use in high school students. The two mentioned variables are able to explain the high rate of substance use in high school students in adverse conditions; and considering them in disaster mental health is essential. Keywords Resilience, Psychological Hardiness, Tendency to Substance Use, High School Students Barriers Against Use of Dental Services among Addicts Receiving Methadone Maintenance Treatment in Rehabilitation Centers in Tehran Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S117 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Hajar Shekarchizadeh1, Mohammad R. Khami2, Simin Z. Mohebbi3, Jorma I. Virtanen4, Hamed Ekhtiari5 1. Community Oral Health Department, Tehran University of Medical Science, Tehran, Iran 2. Community Oral Health Department, Tehran University of Medical Science, Tehran, Iran 3. Community Oral Health Department, Tehran University of Medical Science, Tehran, Iran 4. Department of Community Dentistry, University of Oulu, Oulu, Finland 5. Neurocognitive Laboratory, Iranian National Center for Addiction Studies, Tehran University of Medical Sciences, Tehran, Iran Background and Aim Addicts usually have low use of dental services and ask for only emergency treatment at advanced stages of disease. The aim of the present study was to investigate barriers against dental service utilization among addicts receiving methadone maintenance treatment (MMT) in Tehran, Iran. Methods Applying a stratified cluster random sampling method, we collected the data from 813 MMT patients in eight addiction treatment centers in Tehran in 2011. Participants reported their perceived barriers against use of dental services via a structured selfadministered questionnaire. Face to face interviews also requested patients’ demographics and addiction history. A logistic regression model served for statistical analysis. Results As high as 96% of the participants were men with the mean age of 40.5 (SD±11.5; range 20-86). Most of the patients were married (70%), employed (72%) and had higher than a primaryschool education (89%). The most prevalent main drugs of abuse were opium and crystalline heroin, and the main routes of drug administration were smoking and oral routes. The mean age of starting drug abuse among the patients was 24.8 (SD 8.2), and the mean duration of addiction was 10.8 years (SD 7.9). About half the participants reported to experience dental pain during the previous year. Among them, 44% had visited the dentist for pain relief, as high as 67% self-medicated with painkiller, and 25% abused illicit drugs. More highly educated patients, residents of more affluent areas of the city, and those who had started using drugs at an older age were more likely to visit the dentist to relief dental pain. Low priority for dental care was the most prevalent barrier against use of dental services reported by more than three quarter of the patients. High cost of dental services was the second most prevalent barrier reported by half the patients. Less than a quarter indicated low access to dental treatment among which lack of dentist was the most reported one. Pain and fear of dentists was also revealed by half dentate participants. Conclusion High prevalence of self-medication for toothache and low dental service utilization call for provision of appropriate policies and education to overcome the barriers and to increase dental services utilization among this group of special health care need patients. Keywords Addiction, Use of Dental Services, Barriers Determine the Effect of Treatment on Retention Among Drug Users Peymaneh Shirinbayan1, Hassan Rafiey2, Afshin Vejdani Roshan3, Asgar Dadkhah4, Mohammad Reza Kooshesh5, Ali Farhoudian6 1. Pediatric Neurorehabilitation Researh Center, University of Social Welfare and Rehabilitation 2. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 3. University of Social Welfare and Rehabilitation 4. university of social welfare and rehabilitation 5. Pediatric Neurorehabilitation Researh Center, University of Social Welfare and Rehabilitation 6. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran Background and Aim NTRODUCTION Iran is a country with 70,000,000 populations, which are mostly young. About 2,000,000 Iranians abuse drugs, with the main drug of abuse opiates. Methods METHODS This multi-center prospective study was conducted at 7 outpatient treatment facilities in 4 cities in Iran, in 2007, 282 consecutive opiate dependent people were followed for 6 months. All patients were select after a complete physical and psychiatric evaluation. Criteria for Opioid Dependence in this study was presence of at least three of the following symptoms must occur during a 12 month period: 1) Tolerance, 2) Withdrawal, 3) Opioid use in greater quantities or for longer periods of time than planned,4) Failed attempts to quit or cut back (at minimum, a wish to cut back), 5) Considerable time devoted to obtaining drug, using drug or recovering from use of drug, 6) Interference with social, occupational or recreational activities, and 7) Ongoing use despite awareness of drug problem (American Psychiatric Association, 1994). Dependent variable Length of retention in treatment (0 - 6) considered as dependent variable (main outcome). Results Result At the start of 1.2 patients discontinued treatment and among those who continued treatment, lowest of treatment group received bopre norfin and the highest percentage of people receiving methadone and methadone maintenance At second month, 6.4 subjects discontinued treatment and among those who continued treatment had the lowest percentage of family therapy and individual psychotherapy received the highest percentage of people receiving methadone maintenance. At third month, 7.9 subjects discontinued treatment and among those who continued therapy, individual psychotherapy received the lowest percentage and the highest percentage of people receiving methadone maintenance. At forth month 9.1 of subjects discontinued treatment and among those who continued therapy, cognitive therapy had the lowest and the highest percentage of people receiving methadone maintenance. At five month, 10.9 of the people discontinued treatment and among those who continued treatment had the lowest percentage bopre norfin, group therapy and cognitive therapy had the highest percentage of people receiving MMT and Naltroxan, And the last month, 13.9 patients discontinued treatment and among those who continued therapy, family therapy and group therapy were lowest and the highest percentage of people receiving methadone maintenance S118 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Conclusion Type distribution during the treatment was difference significant (P<0.05) In other words, in each of the months of study, in all cases investigated during methadone maintenance treatment was most consuming. Treatments such as bopre norfin, family therapy, cognitive therapy, group therapy and individual psychotherapy have had the least indication. Keywords Chronic Schizophrenia, Cigarette Smoking, Impulsivity Keywords Retention, Drug Use, Opiate, Family Therapy, Cognitive Therapy, Individual Psychotherapy Comorbidity Cigarette Smoking, among Patients with Schizophrenia: Relationships to Psychopathology, Impulsivity Somayeh Shokrgozar1, Reza Ahmadi2, Masoume Allahi3, Mahboobeh Roshandel rad4 1. Assistance Proffessor of Psychiatry, Department of Psychiatry, Shafa Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran 2. Department of Psychiatry, Shafa Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran 3. Department of Psychiatry, Shafa Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran 4. Department of Psychiatry, Shafa Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran Background and Aim Co-occurring substance use and cigarette smoking in people with schizophrenia is more common in the general population and is associated with poor clinical and social outcomes. In this regard, there are limited data about the relationship between cigarette smoking and psychopathology and impulsivity in patients with schizophrenia. The main objective of this work is to examine the relationship between smoking use and impulsivity, positive and negative symptoms, OCD and demographic Information in the patients with schizophrenia in Iran. Methods In this cross - sectional study, 100 inpatients with chronic schizophrenia in north of Iran were enrolled according to DSM-IV diagnosis and interviewed for nicotine dependency. Psychopathological variables were assessed using the instruments including assessment of positive and negative symptoms (PANSS), scale structured interview DSM-IV (SCID-II), the Yale-Brown obsessive–compulsive scale (YBOCS) and Barratt impulsiveness scale (BIS). Results The results disclosed that smoker with schizophrenia are mostly men with low education and indicate positive symptoms as compared to non-smoking patients with schizophrenia. In the present research unlike other studies, no relationship was found between the severity of negative symptoms and some demographic information such as family history, age of first hospitalization, number of hospitalization times, and smoking. Another important result of this work is that, A significant relationship was found between impulsivity and of nicotine addiction. Conclusion alarmingly high among individuals with schizophrenia in routine psychiatric settings. Occurring cigarette smoking in patients with schizophrenia and communicating with increased morbidity and mortality in them means that coordinated efforts are urgently needed to promote quit smoking in this group. A Comparison of Emotional Intelligence and Self-Esteem with Tendency to Addiction in Orphanage Teenagers and Home Teenagers Zahra Simi1, Om-al-banin Bagher Nezhad2, Mohsen Makhlough3 1. MA in Family Counseling. Allame Tabatabaee, Tehran, Iran. 2. MA in Clinical Psychology. Islamic Azad University, Research Science Unit Mazandaran, Iran. 3. Department of General Psychology, Science and Research Branch, Islamic Azad University, Arak, Iran. Background and Aim The present study was performed with the purpose of comparing emotional intelligence and self-esteem with tendency to addiction in orphanage teenagers and inside home teenagers. Methods This is an applied study in terms of purpose and causative – comparative in term of method. the subjects included all high school students in Mamasani in 1392-1393 who lived in orphanage. the sample consisted of 31 subjects in each group. orphanage students were selected through available sampling and ordinary students were selected through multi-phase clustering. The data was collected through Bardbery and Quiz (2005), copper smith self- esteem (1976) and Farchad tendency to addiction questionaires and were analysed using spass- 18, descriptive statistics and meaningful test of mean difference (T-test). Results The results of the study indicated that there is a meaningful difference between orphanage and ordinary teenagers in terms of emotional intelligence and self – esteem and tendency to addiction. Also, the comparition of means indicate that orphanage teenagers showed more inclination towards addiction. there is also a meaningful relationship between emotional intelligence, self-esteem and inclination towards addiction. In other words, the more emotional intelligence and self-esteem the less inclination towards addiction is. Conclusion It can be said that subjects with low emotional intelligence and low self – esteem are likely to be subjected to drug abuse. Also orphanage life has negative effects on some psychological aspects in teenagers. There is a meaningful relationship between childrens, emotional relationship with affection level and interpersonal relationship with parents and emotional intelligence. Keywords The results of our study showed that prevalence of smoking is Emotional Intelligence, Self-esteem, Addiction, Teenagers Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S119 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Antisocial but not Narcissistic Personality Disorders Features among Polysubstance Users Under MMT Ahmad Sohrabi1, Asrin Rahimmi2, Shahin Fakhraei3 1. Department of Psychology, University of Kurdistan 2. Department of Psychology, Science and Research Branch, Islamic Azad University, Sanandaj 3. Behavioral Diseases Counseling Center, Medical University of Kurdistan Background and Aim Patients with poly-substance use disorders and their personality disorder features have recently attracted attention among researchers (e.g., Preti et al., 2011). This population may have some personality features that draw them into seeking more gains and personal advantages regardless of the cost to others. Personality disorder features, especially those known as cluster B including antisocial and narcissistic personality disorders, are great measures that predict these behaviors, as they mainly involve how one makes a balance between one’s and others’ benefits. Therefore, in the current study we were interested in comparing patients with mono- and poly-substance use disorder regarding these types of personality disorder features. Methods Twenty five addict outpatients under Methadone Maintenance Therapy (MMT) were selected as a convenient sample. They were divided into a couple of groups, mono-substance users (12 opium users) and poly-substance users (13 users of more than a drug). The two groups were homogeneous in terms of age and education as there were no significant differences between the two. All patients filled out a 16-item Narcissistic Disorder Inventory (NPI16, Ames et al., 2006) and antisocial (psychopathy) questionnaire (Levenson et al., 1995), shown good psychometric properties in our previous studies. Results An independent t-test showed a significant difference among the two groups in terms of antisocial personality disorder features (t23=2.1; p < .05, Levene’s Test for Equality of Variances assumed). Both groups were very low on narcissistic disorder features, with no significant differences between the two groups. Further analysis of the data from both groups using Pearson correlation showed a significant negative relationship between age and narcissistic personality disorder (r = -.43; p < .05) and a significant negative relationship between education and antisocial personality disorder (r = -.49; p < .01). No other significant correlations were found. Conclusion The results of the current study showed a higher level of antisocial personality disorder features among poly-substance compared with mono-substance users. However, narcissistic personality disorder features were low among both groups with no significant differences. Moreover, the results also showed a negative relationship between age and narcissistic personality disorder and between education and antisocial personality disorder. Although this was a small study, we can conclude that poly-substance users pursue more benefits and personal gains regardless of possible so- cial consequences, as evident in the antisocial/psychopathy scale items employed in the current study. Surprisingly, they showed very low narcissistic personality disorder features even less than those observed in ordinary people found in previous studies. This might be due to the small sample size or underestimating of features when self-report inventories are employed. Other methods are worth considering, especially more objective scales such as computerized games, as used in our previous studies on topics other than addiction. More details regarding subscales of the questionnaires to be discussed. Keywords Antisocial, Psychopathy, Narcissism, Personality Disorders, Polysubstance, Addiction Alcohol and Traffic Accidents Fatemeh Sokhanvari1, .Mohamemad erisian2 1. Medical Univercity 2. Forensic Center Background and Aim Background: Alcohol has a significant effect on driver behavior, including reducing restraint and caution in the feelings and gain a sense of aggressiveness and risk. While such changes in behavior in a significant impact on traffic safety will only increase due to death. Given alcohol has Very low speed excreted from the body (1/0 g per hour) will surprise even the most cautious drivers . Studies show that the risk of a fatal crash increases two times with a half grams of alcohol per liter of blood flow And 30 percent of fatal accidents with drunk drivers. Methods This study is an cross-sectional descriptive study. study population of drivers who died in traffic accident that referred to the forensic center.Information related to the deceased have been completed by a forensic expert through a questionnaire. Then drug and alcohol testing done for all the dead driver . After receiving the test results recorded. The data obtained were analyzed using SPSS software. Results All subjects studied were male, 53% of primary school education, 21% of college students, 11%% High School education , 10% School education and 5% are illiterate. 84% of the drivers were driving out of city and 16% were driving within the city. 53% of them have driving experience over 10 years, 31% between 1-5 years and 16% were between 5 -10 years. 74% of them were cigarette smokers and 26% had no a history of smoking. 16% of these patients had a history of drug abuse. In 68% of cases has been driving per day and 32% at night. Survey shows that 83% of deaths from accident occurred at accident scene and in 17% of deaths in a week after the incident. In 53% of cases, an accident has been with another vehicle, 31% has been reversal and 16% has been other cases . in toxicology in 37% of cases test positive have been reported. Of which 71% has been alcohol use and 29% has been morphine consumption . Conclusion great damage that alcohol causes in traffic accident due to a lot S120 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall of preventive action. Although many advances have been made, but alcohol still is one of the major factors in traffic deaths in communities where alcohol is used. The results of this study also suggests the creation of fatal accidents are due to alcohol. Thus, according to the official and unofficial reports of high alcohol use, particularly among young people we Need for further cooperation with the Traffic Police and the Transport and Traffic center in our area. Strategies such as using alcohol detector, serious encounters with the drivers of consumer and inform the community about the dangers of alcohol use while driving can also be effective in preventing this problem. It is noteworthy alcohol ue is illegal and forbidden in our country and in the new law, traffic offenses and fined up to 2000000 rials and deduct points from the anticipated license. Keywords Alcohol, Accidents, Death, Forensic Analysis of Amphetamine Type Stimulants in Biological Samples: Forensic and Clinical Aspects Kambiz Soltaninejad1 1. Legal Medicine Research Center, Legal Medicine Organization, Tehran, Iran Background and Aim Nowadays, substance abuse is increasingly shifting from conventional substances like opium, heroin and cannabis to synthetic drugs. One of the important classes of the synthetic abused drugs is central nervous system (CNS) stimulants. In this group, amphetamine-type stimulants (ATS) are the main class which has been illegally manufactured and abused in the world. ATS refer to a group of drugs whose principal members include amphetamine, methamphetamine, ephedrine, pseudoephedrine, methylphenidate, 3,4-methylenedioxymethamphetamine (MDMA) and other related compounds. In Iran, abuse of methamphetamine (with street names such as: Shisheh, Crystal and Glass) is relatively new and growing quickly problem with medical, social, political and legal dimensions. From this view, analysis ATS in bio-samples in amphetamine related addiction/abuse treatment programs, workplace drug testing, driving under influence, treatment of ATS overdoes cases, evaluation of neonatal drug exposure by pregnant woman and differential diagnosis and confirmation of cause of some medical disorders such as substance induced seizures have been used in clinical and forensic toxicology. This article summarizes the biological samples, sample preparation methods and various analytical methods used for the analysis of ATS in biosamples in clinical and medico-legal settings. Conclusion Confirmation and quantification of ATS in bio-samples need to sophisticated and high tech instrumentations especially in medico-legal cases. Method selection related to multiple factors such as sensitivity and accuracy of method, nature of the sample, budget and workload of laboratory and technician experience. Keywords Amphetamine-type Stimulants, Analysis, Abuse, Biological Samples Epidemiological Investigation of Women Visiting DIC Center in Birjand Maryam Soroush1 1. University of Birjand Background and Aim half of our society is women and this statistical truth should be taken into consideration in all social vital aspects of human. Drug addiction is one of prevalent disorders and problems that apply serious and huge damage on individuals and families. Women are prior victim of drug addiction and due to their sensitivity and roles in the families the difficulties in women are more severe. Some of important factors in women’s drug addiction as follow: illness and physical pains, pleasure attainment and curiousness, parent’s spouse and friend’s addiction, economic problems, poverty or high welfare, spiritual and moral problems and so on. Methods Methods We searched the words “Amphetamine-type Stimulants”, “Analysis”, “Determination”, “Biological samples” and “Abuse” in Pubmed and Google Scholar databases from 2000-2014 and the retrieved articles were reviewed. Results forensic settings. Also, other biological samples such as saliva, hair and meconium have been used for the analysis of ATS both in clinical and forensic cases. Tissues especially liver has been only used in forensic cases. Analytical techniques such as onestep rapid immunochromathographic techniques, Thin Layer Chromatography (TLC), High Performance Thin Layer Chromatography (HPTLC), Enzyme-Linked Immunosorbent Assay (ELISA), Fluorescence Polarization Immunoassay (FPIA) and Enzyme Multiplied Immunoassay Technique (EMIT) are used as screening methods for ATS analysis in bio-samples in clinical and medico-legal investigations. High Performance Liquid Chromatography (HPLC) with Photodiode Array (PDA) detector or mass spectrometry (LC-MS) and liquid chromatography with tandem MS (LC-MS-MS), Electrospray Ionization Time-of- Flight Mass Spectrometry (ESI-TOF-MS), Capillary Electrophoresis with MS detection (CE-MS) and Ultra-Performance Liquid Chromatography (UPLC) have been used for conformational analysis of ATS abuse in biological samples in clinical and forensic cases. Urine and blood samples are the most widely used conventional biological samples for the detection of ATS abuse in clinical and This research has been carried out descriptive over 30 medical records of women visited pass healthcare center of Birjand via interview, record compiling and data analysis by SPSS Results Investigating of current study data show the average ages of visitors are 36 among whom %96.7 is married with average of two children. Regarding the type of consumed drug, %33.3 used opium and %50 used glass and crystal. %13.2 of visitors used Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S121 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall more than one type of drug and %87 used the drug for more than 3 years of consumption practice. %70 of them used the drug via smoking and %83.3 has been using the drug between 1-3 times per day. %53.3 of them held prison records and %30 with more than two times addiction treatment records. In terms of effective factors in addiction their self-reported show friends with %70, spiritual disorders with %6.7, physical illness with %6.7 and finally %16.7 pointed out more than one factor effective in their addiction. Conclusion Drug addiction is one of prevalent disorders and problems that apply serious and huge damage on individuals and families. Unfortunately in recent years drug addiction has been prevalent among women as men. Several factors play roles in women addiction and outcomes of women addiction are bigger than men. Prevention of addiction is more effective than treatment and solutions such as education of women with properties of drugs, values and religious believes reinforcement, children control, helping in selection of friends and issuing suitable criminal codes in prevention of addiction in women are most effective and high lighted Keywords Addiction, Women, Pass center, Addiction Treatment The Comparing of Defense Mechanism and Style Among People with Subestance Depanted Disorder and Normal People Reza Soveyzi1, Hossein Mojtahedi2, Mojtaba Habibi3 1. Shahid Beheshti University Of Medical Science Masters In Clinical Psychology, 2. Assistant Professor, Shahid Beheshti University Of Medical Science 3. Assistant Professor, Shahid Beheshti University Background and Aim Introduction:The purpose of the present research was to comparethe the defense styles among patients with substance abuse disorder with non-addicted individuals. Methods The research method was expost factor and statistical population consisted of one group of addicted individual and normal individuals in Tehran. 100 addicted patients were selected by convenient sampling method among the patients that were referred to selected addiction treatment centers in Tehran.The control group with 100 people was selected from normal people. The research instruments were defense style Questionnaire(DSQ-40, Andrews, Sing & Bond, 1993). Data was analyzed using ANOVA. Results Findings revealed significant differences in immature (P<0.01), mature (P<0.001) and Neurotic (P<0.0001) defense styles between addicted and healthy groups. Conclusion It is concluded that awareness of effects of defense styles on substance abuse, can be effective to decrease the addiction disorder and probably to prevent this disorder. Keywords Addiction, Defense Styles. The Role of 1,25 Dihydroxyvitamin D3 in Blood Brain Barrier of MA Addicted Patients Soheil Tahani1, Vahid Shaygannejad2, Leila Dehghani3 1. Department of Neurology, Isfahan Neurosciences Research Center, Isfahan University of Medical Sciences, Isfahan, Iran 2. Department of Neurology, Isfahan Neurosciences Research Center, Isfahan University of Medical Sciences, Isfahan, Iran 3. Department of Neurology, Isfahan Neurosciences Research Center, Isfahan University of Medical Sciences, Isfahan, Iran Background and Aim Methamphetamine also called meth, chalk, ice, and crystal with long-lasting neurotoxic effects is a drug that is considerably abused worldwide. Recent studies in animal models have indicated that MA can induce impairment of the blood-brain barrier (BBB).In addition, functional changes in EC and macrovascular injuries lead blood brain barrier disruption in MA addicted patients. Also it has been suggested that some of the neurotoxic effects of MA abuse could be the consequence of barrier disruption. In the previous studies, it has been proven that vitamin D play a prominent role as strong antioxidant also able to scavenge different ROS. Current study is the first investigation to elucidate positive influences of vitamin D against EC apoptosis in MA addicted. Methods Human umbilical vein endothelial cells (HUVECs) were cultured and then treated with sera from MA addicted patients (30) and sera from healthy volunteer individuals as control group (each group n=20). For evaluation effects of 1,25(OH)2D3 on HUVECs treated with sera of MA addicted patients, we arranged different groups; in the first group, HUVECs were only treated by sera from patients for 24 h, in the second group HUVECs were treated by 10–7 M 1,25(OH)2D3 24 h and then sera from patients was added to these cells for 24 h. In the third group, HUVECs were exposed in the sera of patients for 24 h and then 10–7 M of 1,25(OH)2D3 was added to these cells for 24 h. In the fourth group, HUVECs were treated by sera from healthy individuals for 24 h. MTS assay was carried out for cell surveillance and cell death detection kit and flow cytometry (by annexin V–propidium iodide staining) for evaluating apoptosis were used in this study. Results There was a significant decrement in apoptosis rate by the serum of patients, just when 1,25(OH)2D3 applied before treating HUVECs with sera from MA addicted patients. Furthermore, the cells surveillance improved evidently with the presence of 1,25(OH)(2)D(3) in culture, too. Conclusion With regard to increment in EC apoptosis rate, which treated by the sera from MA addicted patients and decrement in apoptosis rate by the presence of vitamin D in culture media, it could be S122 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall proposed that vitamin D can be used for MA addicted patients to keep EC from high disruption. Keywords Vitamin D3, Apoptosis, Endothelial Cells, Methamphetamine Missing Link in the Tendency to Cybersex Maryam Tavakkoli 1. Tehran Subway, Tehran. Iran 1 Background and Aim This study examined the role of individualindexes organizations took cybersex Methods In this study a sample of 1500 subjects referred to pornographic sites in 93 Were selected. Among these 480 patients were married and were married in 1020. Mental health questionnaires to collect data from Goldberg, Young’s Internet Addiction Scale and Quality of Life Questionnaire for all the samples and the Enrich marital satisfaction and sexual satisfaction for married Hardsvn and those with a sexual partner, were used. data Use Model Regression Case Analysis And Analysis Be Was And Coefficient Determine Calculation Were. Results Results Analysis Regression Show The Evaluation of mental health, marital satisfaction was a significant amount of variance is explained. Conclusion The results provide necessary training, appropriate to their use of alternative mechanisms and above all free from any bias due to the selection and employment of qualified personnel in all areas to address these issues in the period between effective Kvtahtrv other mechanism for pressure responsive. Keywords Methods The method of research is descriptive. Among the addict women have selected 30 subjects who have referred for treatment and they have had formally of 2 years addiction. Then, they have interviewed by open response inventory Results Almost of women were in age of 26-30 years old. The prevalence of crack (60%) and glass (46.6%) has reported as most abuse. Amount of abuse was 1 till 1.5 gram. The way of abuse was smoking (80%), inhalant (6.7%), and injection (13.3%). About 73.3% of women changed their drug in the short time. The cause of drug change was the more hedonism, and the cause of addiction in women was their addict spouse. Conclusion Process of drug abuse in women is more hazardous and different from men. Keywords Dependency, Process of Abuse, Substance, Women The Effectiveness of Matrix Cognitive-Behavioral Therapy on Improvement of Emotional Dependency and Relapse Prevention in Stimulant Drug Abusers Mahnoosh Tavakoli Fard1, Saeed Sadat Mansoori2, Reza Jafari3 1. PhD.Student of Addiction Studies of Tehran University 2. Medical Doctor .Specialist 3. PhD.Student Background and Aim The purpose of this study was the investigation effectiveness of Matrix Cognitive-Behavioral Therapy on improvement of emotional dependency and relapse prevention on stimulant drug Abusers who admitted in therapeutic centers in Rasht. Syber Sex.single, Married Evaluation of Processing the Substance Abuse and Drug Dependency in Iranian Women Mahmood Tavakoli1, Lla Mohamadai2, Mosaieb Yarmohamadi3, Ali Farhoudian4, Frooze Jafari5, Mohammad Hassan Farhadi6, Marjan Rahimi7 1. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 2. PhD Student of Clnical Psychology 3. PhD of Psychology Assstant Professor of Booali Unversty Hamedan Iran 4. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 5. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 6. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 7. Psychologist and Addicton Consultant Background and Aim Methods The method was semi-experimental design with witness group. The population consisted of all methamphetamine users who admitted in therapeutic centers in Rasht during spring in 1393 . By available sampling 30 individual selected and divided randomly to two experimental and witness groups (N=15,per group). Experimental group received 24 sessions of matrix therapy and witness group was not under any training . After the completion of the 12 weeks follow-up period, data were analyzed by independent t-test and covariance and Levens method. Results The results indicated the homogeneity of variance. Also the covariance test showed significant effect of matrix therapy training. Conclusion The aim of this study is evaluation of substance abuse and drug dependency in addicted women in Iran. The results indicated that matrix training was effective in improvement of emotional dependency and relapse prevention towards stimulant drug abusers. Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S123 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Keywords Keywords Matrix, Cognitive Behaviore Therapy, Stimulant Drug Abusers, Emotional Dependency Perceived Attachment, Parenting Styles, Emotion Regulation, Resilience Investigating the Anticipating Role of Perceived Attachment and Parenting Styles in Emotion Regulation Strategies with Mediating Role of Resilience in the Two Normal and Addicted Groups Investigating the Anticipating Role of Sensory Processing Threshold and Perceived Attachment in Emotion Regulation Skills with Mediating Role of Self-Conscious Emotions in Addicted and Normal Groups Alireza Tolooee Qarachanaq1, Aliakbar Pormouzeh2, Mohamad Mirzaloo3 1. MA in Clinical Psychology 2. MA in Translation Studies 3. MA in Clinical Psychology Background and Aim Based on the issues and theories related to relationship of cognition, affection and importance of personality constructs in facing internal and external stress, the anticipating role of perceived attachment and parenting styles in skills of emotion regulation with mediating role of resilience. Lack of an equilibrium ratio of kindness and parental control causes the sense of insecurity and formation of ineffective cognitive psychological constructs (insecure internal functional models) including anger, self-blame, the automatic negative thoughts and ineffective emotion regulation skills. Contrary, transferring the sense of security provides free self-discovery opportunities and reaching at a state of cognitive integrity and also mature and efficient cognitive regulation skills. Literature shows that secure attachment style with appropriate and flexible compatibility against emotional experiences and high resilience is related to facing internal and environmental stresses. Methods In this descriptive study participants including 300 individuals were normal (n=150) and addicted (n=150) individuals who referred to the addiction treatment centers in the Tehran city. Participants answered perceived attachment and parenting styles, emotion regulation strategies and resilience questionnaires. Research hypotheses were analyzed using Pearson correlative coefficient, two-way variance analysis and multivariate regression tests. Results The perceived attachment and parenting styles together were able to anticipate resilience. Resilience variable was a feature with personality stability in anticipating the skills of efficient emotion regulation in addicted and normal individuals. Perceived attachment and parenting styles as negative affection anticipation result in inefficient affection regulation in the addicted group (P<0.01). Conclusion A part of research findings support the role of training and family factors in stabilizing the positive personality constructs like resilience. The variable of resilience as an individual personality variable anticipates emotion regulation skills in normal and addicted individuals. In addition findings of this study about interaction of interpersonal and intrapersonal factors in resilience against stressful conditions including social pressures offer application and theoretical implications. Alireza Tolooee Qarachanaq1, Aliakbar Pormouzeh2, Mohammad Mirzaloo3 1. MA in Clinical Psychology 2. MA in Translation Studies 3. MA in Clinical Psychology Background and Aim During last decades there were clear interpretations of individuals’ tendency to drug abuse that involved a wide range of genetic, psychological, family and social factors. Sensory processing threshold as a personality and biological factor along with the theory of attachment as an environmental factor can explain individual differences in regulation and perception of emotions. Individuals with different mental attachment models try to regulate and manage emotions and affections based on previously learnt and supported practices. Meantime, introducing mutual relationship between infants’ biological features and environmental features may well explain stable personality features in addiction including self-conscious emotions and emotion regulation skills and causes taking an etiology and monotonous approach toward emotional problems in addicted individuals. Methods This study is a descriptive analysis of participants containing 320 individuals in the two normal (n=160) and addicted (n=160) groups. Samples were selected from among individuals who referred to addiction treatment centers in the city of Tehran. Individuals answered sensory processing threshold, perceived attachment styles, and self-conscious and self-regulation questionnaires. Research hypotheses were analyzed using Pearson correlative coefficient, two-way variance analysis and multivariate regression tests. Results The mutual impact of sensory processing threshold and perceived attachment styles causes self-conscious affections and significant anticipating self-conscious emotions for self-regulatory skills in normal and addicted individuals (P<0.01). Conclusion A part of results reinforces mutual impact of sensory processing threshold as a biological fundamental factor and perceived attachment as environmental factor in justifying the impacts of self-conscious affections on emotional functions. In addition, findings of this study about affection and cognitive mutual styles and also the role of positive affect offers applications and theoretical implications in improving regulation of emotions and solving interpersonal and intrapersonal issues. S124 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Keywords Sensory Processing Threshold, Perceived Attachment, SelfConscious Emotions, Emotion Regulation Skills Orexin Receptor Antagonists as a Novel Approach in Treating Insomnia Among Stimulant Abusers; Evolving Evidence and Practical Implications Mohammad Totabi Nami1, Mohammad Torabi Nami2, Bijan Zare3 1. Department of Neuroscience, School of Advanced Medical Science and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran 2. Department of Neuroscience, School of Advanced Medical Science and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran 3. Department of Medical Biotechnology, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran. Background and Aim The dual orexin receptor anatagonists -DORAs- are a newly introduced class of sleep promoting agents which has shown to properly induce sleep without inhibiting the neural activity. Stimulant abuse and methamphethamine dependence in particular, are shown to facilitate the brain stem wake-promoting system. Druginduced insomnia and stimulants withdrawal-related hypersomnolence are deemed as the most frequent and serious sleep disturbances among methamphethamine abusers. Although evidence have supported the potent hypnotic actions of orexin-A and-B antagonist, suvorexant (MK-4305), little is known about neurocognitive performance in the presence of such a newly introduced medication. DORAs are known to induce sleep by disfacilitation of wake-promoting systems whereas GABA receptor modulators such as zolpidem induce sleep through inhibition of neural activity. The hypothesis of less functional compromise following the use of DORAs as compared to GABA receptor agonists deserves precise evaluation. Methods In a pilot study, we evaluated rats’ performance in elevated plus maze -EPM- in the presence of MK-4305 versus vehicle. Performance in aversive memory retrieval task and locomotor activity were assessed upon the retest EPM evaluation after 100 mg/kg, po administration of MK-4305 or vehicle following 24 hrs of undisturbed and sleep-deprived condition through gentle handling. Results Our interim results analysis suggested equivalent performance in MK-4305- vs. vehicle-treated animals with regard to memory retrieval and anxiety indices such as open-arm time (OAT%), open-arm entries (OAE%) and locomotor activity. We hypothesized that stimulants-induced insomnia in rats can also be appropriately modulated by the sleep-promoting effects of MK-4305 while the cognitive performance is less affected as compared to GABA agonists. Methamphetamine abusers frequently complain of insomnia and withdrawal-related hypersomnia. As sleep disorders in addiction is bidirectional (poor sleep may promote the risk of relapse and substance abuse induces persistent sleep disorders), treating sleep disturbances in substance abusers is expected to contribute to their more effective management. Conclusion Suvorexant (MK-4305) is currently approved by FDA to be used in most patients at 10 mg starting dose which can be increased to 15 and 20 mg if well-tolerated in patients. The role of this dual orexin receptor antagonist, as a novel sleep promoting agents in treating stimulant-dependent sleep disorders needs further evaluation in clinical setting and well-designed head to head comparative clinical trials. The possible comparative advantages of suvorexant versus benzodiazepines or GABA receptor agonists including zolpidem should be more clearly defined. Keywords Insomnia; Sleep Disorders; Addiction; Stimulants; DORA; Suvorexant The Effect of Escalating Dose, Multiple Binge Methamphetamine Regimen, and Alcohol Combination on Spatial Memory and Oxidative Stress Markers in Rat Brain Ladan Vaghef1, Shirin Babri2, Mohammad Moghaddam Vahed 3 1. Faculty of Education and Psychology, University of Tabriz; Tabriz, Iran 2. Drug Applied Research Center (DARC) of Tabriz University of Medical Sciences; Tabriz, Iran, 5166614776 3. Faculty of agriculture, University of Tabriz; Tabriz, Iran. Background and Aim Polydrug abuse is a major problem around the world. Methamphetamine (MA) and alcohol (AL) are two abused drugs which are frequently used together. Chronic abuse of either MA or AL causes oxidative stress in the brain and is associated with impairments in cognitive functions including various aspects of memory and learning. The present study examined the effect of escalating dose, multiple binge MA regimen, AL and MA-AL combination on spatial memory and the induction of oxidative stress in the hippocampus. Methods Adult male Wistar rats were exposed to ethanol, an escalating dose of MA either individually or in combination for 28 consecutive days. In order to examine the short- and long-term effects of chronic exposure to the drugs, each group was then subdivided into two further groups. Thereafter, spatial memory was tested using a Morris water maze, either one day or 14 days after the drugs were withdrawn. At the end of the behavioral testing, oxidative stress markers including superoxide dismutase (SOD), glutathione peroxidase (GPX), Catalase (CAT), and Malondialdehyde (MDA) were measured. Results Our results showed that MA, but not AL, impaired spatial memory. Although AL alone had no effect, it exacerbated the impairment due to MA when the drugs were co-administered. In addition, while both drugs significantly induced oxidative stress in the hippocampus when given alone, co-administration of these drugs resulted in a greater oxidative stress and an impairment of the antioxidant enzyme glutathione peroxidase in rat hippocampus. Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S125 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Conclusion Taken together, this study demonstrates that MA in combination with AL has synergistic effects on increased oxidative stress in the hippocampus, as well as spatial memory impairment. Keywords Background and Aim Addiction is characterized by the pathological pattern of drug seeking; the state in which an individual loses control over the use of substances despite the adverse consequences associated with substance use. It is the most troubling aspect of dependency. Methamphetamine, Alcohol, Spatial Memory, Oxidative Stress, Hippocampus Methods Effects of Different Treadmill Running Protocols on Ethanol-Induced Spatial Memory Impairment in Adult Rats Results Touraj Hashemi1, Ladan Vaghef2, Shirin Babri3 1. Faculty of Education and Psychology, University of Tabriz 2. Faculty of Education and Psychology, University of Tabriz 3. Neuroscience Research Center of Tabriz University of Medical Sciences; Tabriz, Iran Background and Aim Chronic ethanol consumption is often accompanied by numerous cognitive deficits and may lead to long-lasting impairments in spatial learning and memory. The aim of the present study was to evaluate the therapeutic potential of regular treadmill exercise on hippocampal-dependent memory in ethanol-treated rats. Methods Adult male Wistar rats were exposed to ethanol (4 g/kg, 20% v/v for four weeks) and effects of three exercise protocols (preethanol, post-ethanol and pre-to-post-ethanol treatment) were examined. Spatial memory was tested in a Morris Water Maze task. Results Results showed that ethanol exposure resulted in longer escape latencies during the acquisition phase of the Morris Water Maze task. Moreover, all three exercise protocols significantly decreased the latency to locate the hidden platform. During probe trial, ethanol led to the decreased time spent in target quadrant. In contrast, performance on the probe trial was significantly improved following the post- and pre-to-post-ethanol, but not pre-ethanol, exercises. Conclusion These findings suggest that treadmill running can attenuate the adverse effects of chronic ethanol exposure on spatial memory, and may serve as a non-pharmacological alcohol abuse treatment. Keywords Forced Exercise, Ethanol, Spatial Memory, Hippocampus, Morris Water Maze, Rat Addiction Susceptibility and Adolescents: Evidence for Psychosocial Development of Addiction Rogayeh Vahdat 1, Ali Zeinali2 1. Assistant professor, Department of Educational Sciences, Islamic Azad University; Urmia Branch, Urmia, Iran. 2. Assistant professor, Dept. of Psychology, Islamic Azad University; Khoy Branch, Khoy, Iran This paper is a review study. Studies show the disease of addiction can not be created immediately. Despite access to addictive drugs, if a person is not prone to addiction; he or she won’t develop addiction. The addicts are individuals that some substance is added to their pathological development backgrounds. Tendency for substance and abuse it, developmental unhealthy background and special personal proneness is necessary that without it addiction disease is not caused. Conclusion This preparation has been described as addiction susceptibility that an adolescence stage is the peak of its expression. Therefore, in addiction, the prevention is the only solution to prevent the disease of addiction. In addiction treatment, in addition to the drug therapy, six pathological development background and destroyed psycho-social aspects, should be paid attention strictly. Keywords Addiction Susceptibility, Adolescent, Psycho-Social Development, Addiction The Effect of Methadone and Valproate Combination on Morphine Withdrawal-Induced Anxiety and Depression in Male Mice Samira vahidi1, Mohsen Khalili2, Zahra Kiasalari3, Esmat Yaghoutpoor4 1. Dept. of Biology, Faculty of Sciences, Shahed University, Tehran, Iran 2. Neurophysiology Research Center, Shahed University, Tehran, Iran 3. Neurophysiology Research Center, Shahed University, Tehran, Iran 4. Dept. of Biology, Faculty of Sciences, Shahed University, Tehran, Iran Background and Aim Today, opioids are used to control and relieve acute and chronic pain. But patients after withdrawal, experience unpleasant conditions such as anxiety and depression. On the other hand according to the inefficiency of existing treatments, and the new sciences recommendation of drug combination therapy for diseases in modern pharmacology, the present study has examined the effects of methadone and valproate combination on morphine withdrawal-induced anxiety and depression. Methods Ninety-eight male mice were divided into acute and chronic categories that allocated into 7 groups of 7mice following: saline, morphine, methadone, valproate, three groups of valproate+methadone, i.e 1 to 1, 2 to 1 and 1 to 2 ratio. Except saline group the others were received escalating dose of morphine for 8 consecutive days. In chronic group, drugs were injected for S126 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall 30 minutes before morphine administration. But in acute group, the drugs were used only at 8th day (test day) as mentioned method. Anxiety and depression due to naloxone precipitation was investigated by Elevated Plus-Maze, Tail-Suspension and Open Field tests. Data were analyzed using Sigma Stat, one-way ANOVA, Tukey, and Kruskall-Wallis tests. Results Chronic administration of drugs in Plus-Maze test, valproate2+methadone1 combination therapy group had shown a significant increase in the percentage of open arm entries (53.86±1.9) and percentage of time spent in the open arm (58.58±4.15) compared to the morphine group, with a percentage of entering (28.12±2.03) and percentage of time (17.88±1.77) and also in Open Field test, the ratio of the number to the duration of time spent in the central square, in the combination therapy groups of methadone+valproate(27±2), valproate1+methadone2 (26±2) and valproate2+methadone1 (23±3) compared to the morphine group (7±3) was significantly increased that indicates an anxiety decrease in above groups. In Tail-Suspension test, duration of immobility as an indicator of depression, in the treatment group of valproate2+methadone1 was significantly decreased (P<0.001). Conclusion Our results shown that probably methadone and valproate combination treatment could reduce morphine withdrawal-induced anxiety and depression more than single treatments. Keywords Anxiety, Depression, Methadone, Valproate, Mice Study Relationship between Marginal Settlement with Kind of Opioids in Izadshahr’s Ahangarmahalleh in Mazandaran. Ali Vatandost1, Mitra Shaabanpoor2 1. MA Student of Psychology .Manager and Psychologist of Wean Opioids Bozorgmehr Center in WO’s Amool. Manager of DIC Omid in Noor. 2. Social Science Expert, Technical Liable in DIC in Noor. Background and Aim Introduction: Marginal settlement as one of big social problems is a phenomenon that is a challenge and social harm in most cities because there are suitable situation for crime and social harms in this area, sociologist and criminologist consider it, especially buying and selling of opioids is one of serious harms in this area. Purpose: The purpose of this research show the influence of marginal settlement an addiction in areas (Izadshahr Ahangarmahalleh ) in Mazandaran. So answer the question this research that: are there only more pollution of opioids in this areas and are there meaningful relationship between marginal settlement and man addiction. Methods This research is field method. Prepared inventory was given to answer, and then answers were analyzed as descriptive and statistical.Statistical population was 860 man of shanty towns inhabitant in Izadshahr’s Ahangarmahalleh and ketty ya. Sample were selected 130 man among 860 men by random of inhabitant Izadshahr’s Ahangarmahalleh and ketty ya. Data collection instrument was inventory .Inventory involved individual information ,question about ill as AIDS, Hepatitis so, individual antecedent about crime ,prison , use opioids ,kind , period of use then antecedent wean of opioids and main factor of use opioids. Results Research area was Izadshahr’s Ahangarmahalleh and ketty ya .Range of age answerer was from 20 to 30 years old that they were selected by random method The results show that there isn’t meaningful relationship between shanty town areas and social deviation because there is as this deviations less or more in other areas. Conclusion Shanty town people enjoy less participant and rights urban and they don’t satisfy to prepared services. Consider to spread poverty and unemployment, shanty town people encounter social harms. Shanty town areas have unique particular but some part of particular involve poverty, risk behavior and social harms have same situation. Study of addiction situation in shanty town people show that studied areas (Ahangarmahalleh and ketty ya) have same portion in this situation. That mean there are areas with more and more crime and use opioids and are center of immorality, crime, addiction and social harms. We can’t say social harms as addiction is more and more in shanty town than other urban areas. We can only think to strong and weak it because there is more harm in modern urban areas. Keywords Marginal Settlement, Social Harms, Crime, Traditional and Industrial Opioids. Development of Immunochromatographic Assay for Detection of Amphetamine in Human Saliva Sample Nazanin Vaziritabar1, Mohammad Javad Rasae2 1. Department of Biochemistry, Faculty of Medical Sciences, Tarbiat Modares University ,Tehran – Iran 2. Department of Biochemistry, Faculty of Medical Sciences, Tarbiat Modares University ,Tehran – Iran Background and Aim Methamphetamine is a psycho-stimulant and one of the main drugs around the world. In recent decades, industrial production and abuse of methamphetamine has increased dramatically, and this has led to a threat in world health and welfare. In order to reduce the growing methamphetamine abuse and its devastating effects on the community, effective methods for detecting methamphetamine abusers are required. Due to the simplicity, sensitivity, and the availability of suitable locations where immune-assays can be done, they are used for screening of biological samples for drug abuse detection. In this study an Immunochromatographic assay was designed to detect methamphetamine in human saliva samples. Methods In order to make the antigen which is used in the assay the car- Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S127 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall boxylate derivative of methamphetamine was synthesized and with carbodiimide-method, it has been conjugated with BSA. The synthesized antigen was injected to two rabbits in 11 innings to produce the polyclonal antibody. The produced antibody was investigated by ELISA method and after purification was conjugated with (attached to) gold nanoparticles. By the immobilization of produced antigen at the test line on the nitrocellulose membrane and placing the gold labeled antibody in the sample pad position, immunochromatographic assay for methamphetamine detection in the saliva was designed. Results Data obtained from IR spectroscopy spectrums confirmed the synthesis of carboxylate derivative of methamphetamine. UV spectrophotometry spectrums in 278 nm showed the formation of BSA-METH conjugate. The ELISA data indicated the production of polyclonal antibodies against methamphetamine. Conclusion Using antigen and produced antibody, the immunochromatographic assay for identification of methamphetamin in saliva sample with 50 ng/ mL cut off, which is a suitable cut off for detecting methamphetamin in the saliva, was designed. Keywords Methamphetamine, Immune Assays, Immunochromatographic Assays A Comparison of Parent – Child Relationship in Alcohol Users and Non-alcohol Users’ Students Mahboobe Taher1, Aida Yahyazadeh2, Mahsa Mojallal3, Abbas Ali Hosein Khanzadeh4 1. PhD Student in Psychology, University of Mohaghegh Ardabili 2. Graduate Student in Clinical Psychology, Islamic Azad University of Rasht, Research and Science Branch 3. Master of psychology, University of Guilan 4. Assistant Professor at Department of Psychology, University of Guilan Background and Aim The parent – child relationship factors such as poor familial attachment quality, low levels of parental monitoring and strict, inadequate parental supervision, and lack of compassion, concern, and involvement of parents, are association with drinking alcohol in children.the aim of present study was to compare of parent child relationship in alcohol users and non-alcohol users’ students. Methods The statistical population of this causal-comparative study consisted of all students of Guilan University in 2012-2013 academic year that from among them a sample of 241 students (97 users and 144 non-users) were selected by purposive sampling and responded to the Parent-child Relationship Scale and Information Demographic Questionnaire. Results t-test results showed that there is significant different between parent - child relationship in alcohol users and non-alcohol users’ students. Also, MANOVA results indicated that alcohol users students’ scores on the total score of the relationship with mother and positive affect, hurt/ confusion of roles, and replication dimensions, was lower than non-alcohol users significantly. Conclusion Negligence of parent, especially mother, in connection with the child`s affection needs, lake of the supportive people that to obviate the care needs of child, non-responsive and non- sensitive parent, lake of a common sympathy in face with difficulties, numerous criticisms, exceeded expectations and lack of the skills to adaptation with new situations, attract youth toward alcohol consumption. Keywords Parent – Child Relationship, Alcohol Users’ Students, Non-alcohol Users’ Students Effectiveness of Methadone Maintenance Treatment on the Mental Health of Harm Reduction Services’ Recipients in Drop-In Centers Mosaiyb Yarmohamadi Vasel1, Ahmad Bayat2, Mahmoud Tavakoli3, Ali Farhoudian4, Mohamad Hasan Farhadi5, Fatemeh Sharifi6 1. PhD. of Psychology, Assistant Professor of Psychology Department, Buali Sina University, Hamadan, Iran 2. M.Sc. of Psychology, Tabriz University, Iran 3. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 4. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 5. PhD. Student of Cognitive Neuroscience, Substance Abuse and Dependency Research Center, University of Social Welfare & Rehabilitation Sciences, Tehran, Iran 6. B.Sc. of Psychology, Buali Sina University, Hamadan, Iran Background and Aim Objective: The purpose of this study was to examine the effectiveness of methadone maintenance treatment (MMT) on the mental health of harm reduction services’ recipients in Hamedan’s drop-in centers (DIC). Methods This research was a quasi experimental study. The statistical population consisted of 200 subjects. Sixty individuals (30 MMT recipients and 30 harm reduction services’ recipients) were selected through convenient sampling. The data was collected with the SCL 90 Inventory. Data was analyzed with T-Test for independent groups. Results The findings showed significant differences between the mental health of MMT recipients and harm reduction services’ recipients in DIC. The mental health of MMT recipients was higher than harm reduction services’ recipients (P < 0/001). Conclusion In conclusion, MMT is more effective than harm reduction services (DIC) in improving clients’ mental health status. S128 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Keywords Mental Health , Methadone Maintenance Treatment , Drop In Center , Harm Reduction Factors Associated with Prevalence of Drug Abuse and Substance Dependence In Hamadan Villages Mosaiyb Yarmohamadi vasel1, Fatemeh Ghannadi2, Omid Massah3 1. Ph.D. of Psychology, Assistant Professor of Psychology Department, Buali Sina University, Hamadan, Iran 2. M.Sc, psychology of Kharazmi university,Tehran, Iran 3. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran Background and Aim In recent years according to the the development of drug use and a wrong culture of drug abuse in Iran country, prevalence drug use has increased in the city of Razan and subsidiary villages. Thus, The aim of this study was to investigate the causes of prevalence of drug abuse and substance dependence in the Razancity. Methods The method in this study was qualitative. The statistical population consisted of all the key individuals and drug users Razan city. The research sample included 100 individuals who included: 1) 30 drug abusers, 2) 10 family members of drug abusers and dependents, 3) 30 expert of addiction knowledge, 4) 30 key individuals in Razan city. Data was collected by 1) semi-structured questionnaire of “determining the drug abuse situation” 2) indepth individual interview and focus group discussion. The qualitative data obtained from semi-structured questionnaires and focus group discussions, were extracted and analyzed using content analysis methods. Results The findings indicated that the age of initiation into injection drugs is 24 and the education level of drug abusers was low. The most common drug used is opium but the use of new substances such crystal was expanding. Findings suggest wrong wedding ceremony traditions, circumcision celebrations, positive attitude to drug use, agriculture farms, mosaic manufacturers, combine drivers, availability of drugs, insignificant punishments for drug distributors and users, Parents’ lack of knowledge and awareness about the effects and consequences of drug use, Lack of necessary skills against with substance abuse, Lack of the environmental accommodations for the leisure time of adolescents and young adults, Poor parenting styles, Lack of parental supervision on their children’s behavior, were among the most important reasons of drug use prevalence in Razancity and subsidiary villages. Conclusion This study revealed that several factors contribute to the onset of drug use in Razancity, That preventive interventions should to consider this risk factors in initiation of drug use. Keywords Prevalence, Drug Abuse, Substance Dependence, Hamadan Villages Psychosocial Predictors of Initiation into Injection Drugs Fatemeh Ghannadi1, Mosaiyb Yarmohamadi vasel2, Ali Farhoudian3 1. MSc, psychology of kharazmi university,Tehran, Iran 2. PhD. of Psychology, Assistant Professor of Psychology Department, Buali Sina University, Hamadan, Iran 3. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran Background and Aim Many underlie factors affects injecting drug and conditions around the first injection experience is full of complex psychological and social factors. Thus purpose of this study was identify of psychosocial predictors of initiation into injection drugs among substance abusers. Methods Study method was cross- sectional study. Research Statistics universe constitutes of all People suffering substance dependence disorder with pattern of injection usein Tehran and Hamedan citys. This study conducted among 255 individual with substance dependence disorder that selected from harm reduction centers in Tehran and Hamedan citys, The sampling selection method was simple random. The instruments used for data collection was included: demographic information, patterns of drug use and initiation of injection scales, SCL90-R questionnaire, Data analyzed using multivariate regression analysis. Results Results showed psychosocial predictors of initiation into injection drugs were homelessness, unemployment, Euphoria, aggression, curiosity, age of initiation drug use, peer pressure, faster effect of injection drugs. Conclusion Finally, should be said that injection drug use is a very complex phenomenon that in studies transition from drug abuse to initiation of injection drug use is associated with different factors, that understanding of these factors is useful to design successful prevention approaches or delaying the to initiation of injection. Keywords Psychosocial Predictors, Initiation, Injection Drugs, First Injection The Relationship between the Place of Residence and Initiation of Injection in Drug Users Mosaiyb Yarmohamadi vasel1, Fatemeh Ghannadi2, Mohammad Hasan Farhadi3 1. PhD. of Psychology, Assistant Professor of Psychology Department, Buali Sina University, Hamadan, Iran 2. MSc, Psychology of Kharazmi University,Tehran, Iran 3. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran Background and Aim Residents of risky areas may find themselves in danger of using Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S129 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall drug abuse as a consequence of socioeconomic structure of their surroundings. Studies have indicated that being exposed to environments in which drug use is prevalent, may be the leading cause of injection initiation hazards. Hence, the objective of this study is to investigate the relationship between living in risky neighborhoods and initiation of injection. Methods This was a cross-sectional study. The Statistics universe included all the drug abusers with pattern of injection use in Hamedan and Tehran cities. The participants were 255 individual with substance dependence disorder that selected from harm reduction centers in Tehran and Hamedan ,The sampling method was simple random. The instruments used were demographic information and patterns of drug use and initiation of injection scales. Results Findings showed that people were living in risky areas initiated injection of drugs much sooner than other addicts. Also, they mostly chose ruined areas after adopting pattern of injection use. Conclusion Thus, risky areas are considered a great hazard regarding injecting drug use among youth. In this sense, preventative interventions and preventative education programs in such areas are to be considered seriously for this purpose. Keywords Risky place, Initiation, Injection, Drug users Effectiveness of Resiliency Skills Training in Reducing High-Risk Behaviors of Students Farideh Piri1, Mosaiyb Yarmohamadi vasel2, Khosro Rashid3, Ali Farhoudian4 1. MSc, Psychology of Buali Sina University, Hamadan, Iran 2. PhD. of Psychology, Assistant Professor of Psychology Department, Buali Sina University, Hamadan, Iran 3. PhD. of Psychology, Assistant Professor of Psychology Department, Buali Sina University, Hamadan, Iran 4. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran Background and Aim Resilience indicates an individual’s ability to re-adapt in face of unpleasant circumstances in life and if one is trained in this regard, one would be able to increase capacity against stress, unpleasant events and hardships in the surroundings and to solve problems. Thus, the objective of this study was to evaluate the effectiveness of resiliency skills training in reducing high-risk behaviors of students. Methods Study method was quasi-experimental and research design was pre-tests and post-tests with control and experimental groups. The research Statistics universe of the study included all the female high school students of Hamedan province in 2014. The participants were 15 students in control group and 15 in the experimental group who were selected randomly. Then, the resilience-training program was administered for 12 sessions, 1.5 hours per week for the experimental group. The instruments used were The ConnorDavidson Resilience scale (CD-RISC) and high-risk behaviors questionnaire. To compare the effects of the intervention, pretest and posttest was given to both groups. Data analyzed using Covariance analysis test. Results Results showed resiliency skills training was effective in reducing high-risk behaviors of students. Also, The resiliency skills training was effective for high-risk behaviors of violence and substance use of students. Conclusion Therefore, according to the effectiveness of resiliency skills training program in reducing high-risk behaviors, it is suggested that teachers and educators incorporate resiliency training in their curricula for reducing students’ high-risk behaviors. Keywords Resiliency, High-Risk Behaviors, Violence and Substance Use The Role of Deterministic Thinking in Mental Health of Substance Abusers Who Involved Rehabilitation Program Seyyed Jalal Younesi1, Mohammad Ebrahimi2, Hadi Gholam Mohammadi3 1. University of Social Welfare and Rehabilitation Sciences 2. University of Social Welfare and Rehabilitation Sciences 3. University of Social Welfare and Rehabilitation Sciences Background and Aim The current research is to investigate the relation between deterministic thinking and mental health among the drug abusers, in which it considers and clarifies the role of cognitive distortions by focusing on deterministic thinking. Methods The present study is descriptive and correlative. All the individuals with experience of drug abusing who referred to Shafag rehabilitation center located in Kahrizak were considered as statistical population. 110 individuals who were addicted to drugs (stimulus and Metamephtalin) were selected from the population by the purposeful sampling method to answer the questionnaires of deterministic thinking and general health (GHQ). For data analysis were used Pearsonian coefficient correlation and regression analysis was used. Results The results showed that there is a positive and significant relation between deterministic thinking and the lack of mental health at the statistical level [R=%22, P<0/05] and had the closest relation with deterministic thinking among the factors of mental health anxiety and depression. It was found that definitiveness in predicting tragic events and then in future anticipation (two factors of deterministic thinking are the most vigorous variables that predict the lack of mental health. Conclusion It seems that the drug abusers to suffer deterministic thinking, S130 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall when they to confront with difficult situations, they would be more affected by depression and anxiety. This way of thinking may play a major role by impelling or restraining drug addiction. Keywords Deterministic Thinking, Mental Health, Drug Abuse, Rehabilitation Keywords Oral Cancer, Alcohol, Tobacco, Smoking A Study of Structural Factors Affecting the Propensity to Addiction in Iranian Society Fatemeh Zandi1, Maryam Rezaie Dareh Deh2 1. Bualisina University Hamedan Iran 2. Bualisina University Hamedan Iran Alcohol, Tobacco, Smoking and the Risk of Oral Cancer Samira Yousefnorozi 1, Elham Davari Dolatabadi2 1. Ba Nursing Student, Khorasgan Azad University, Young Researchers Club, Isfahan, Iran 2. Faculty Member, Department of Nursing, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran Background and Aim Worldwide, oral cancer represents approximately 5 per cent of all malignant lesions, with over 800 new intra-oral squamous cell carcinomas .Despite recent advances in therapy, the five-year survival rate remains around 50 per cent and the sequelae of treatment can be seriously debilitating. It has been long established that smoking, alcohol consumption, as well as tobacco chewing are risk factors linked to the development of oral cancer. Methods This review assesses the epidemiological evidence, supportive in vitro studies and mechanism by which alcohol tobacco and smoking is involved in the development of oral cancer with extensive searches in PubMed, ProQuest, science direct and google scholar databases by oral cancer, alcohol, tobacco, and smoking keywords. Results These studies have shown that among alcoholic consumers and smokers the risk of oral cancer tended to combine more in a multiplicative than additive fashion and were increased more than 35fold among those who consumed two or more packs of cigarettes and more than four alcoholic drinks/day. Cigarette, cigar, and pipe smoking were separately implicated, although it has shown that risk was not as high among male lifelong filter cigarette smokers. In other researches it have found that Cessation of smoking was associated with a sharply reduced risk of this cancer, with no excess detected among those having quit for 10 or more years, suggesting that smoking affects primarily a late stage in the process of oral carcinogenesis. Another research has shown the risks varied by type of alcoholic beverage, being higher among those consuming hard liquor or beer than wine. Conclusion In summary these studies implicates tobacco smoking and alcohol drinking as the major determinants of oral cancer. Either product alone can induce this cancer although most studies result from the combined effect of smoking and drinking. Thus measures to prevent oral cancer should be aimed at reducing intake of both alcohol and tobacco. These studies also provide new leads regarding differential effect by type of product, including the lower risk associated with filter cigarettes and with intake of wine compared to beer or liquor. Background and Aim Addiction has become a social issue of concern for researchers and social planners due to its destructive nature that affects the mental and social health issues. To investigate the structural causes of addiction propensity in the Iranian society today, this study firstly briefly discusses these factors: the transition from traditional to modern (or pre-modern) society in the contemporary Iran; revolution and the changes it has caused; the population explosion in the sixties; and the increase in the urban population without the provision of culturally appropriate structures.Then, the effects of these factors are discussedthrough the theories of “Social Identity” by Tajfl, “Social Control” byHyryshy, “Failing Dignity” by Albert Cohen,“Anomie” by Merton, and finally, “Leisure” by Simmel. Some of these effects are “the generationgap”, “low social capital”, “inaccessibility of goals” and ultimately, “individualism and the desire to be different”. Methods Meteanalysis Results Conditions of the transition from traditional to modern and semimodern, Revolution and the changes it caused some changes in the population explosion of the sixties and the increase in population structure and culture of cities without providing the proper urbanization Factors in society has created The tendency of the population, especially young people, addiction has contributed to These factors include: 1. Create a generational gap between parents and children, leading to a lack of understanding toward each other in the family environment (as the first and most established resort identity and emotional) is 2. Their low social capital resulting from the transition from traditional to modern society and the lack of timely and appropriate shaping component of modern relationships such as community relations, trust administrators, trust unfamiliar, sense of belonging to others and social acceptance; group identity and social identity, thus disrupting the drug is causing widespread social damage. The theory of “social identity” Tajfl and social control theory Hyryshy of theories that explain the causes are.. Conclusion Failing to achieve its objectives, the factors that explain the development of societies in transition to modernize and media advertising and encouraging the consumption Modern society encourages people to earn a livelihood can But most of them do not make it possible to achieve Dhdbh explain why people tend to deal with addiction.¬ These factors also explain the failure of theoretical theories of Albert Cohen and dignity are Merton’s theory of anomie. 4. Individualism and the desire to be different, these Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S131 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall factors also born the modern world’s increasing dependence of intense social and personal freedoms in modern society In response to a compulsory social constraints action does the non-normative Explain the tendency to addiction, especially in the upper stratum of society pays It also explains the theory and Leisure Simmel’s theory is used in. Keywords Addiction, Structures, Failure Status, Anomie, Leisure, Generation gap The Efficacy of Motivational Interviewing on Decreasing Male Addicts’ Sexual High Risk Behaviors Farshad Zarei1, Seyyed Jalal Younesi2, Farshad Bahari3, Mahdi Arabzadeh4, Mahmoud Tavakoli5 1. MA Student of Rehabilitation Counseling, Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran. (Corresponding author). farshadzm@yahoo.com 2. PhD. of Clinical Psychology, Assistant Professor of Counseling, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran. 3. University of Social Welfare and Rehabilitation Sciences, Tehran. 4. Assistant Professor of Educational Psychology, Kharazmi University. 5. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran Background and Aim Studies have shown that high-risk sexual behaviors are one of the main reasons for AIDS transmission. The rate of high-risk sexual behaviors is high among addicts. The aim of the current study was to determine the efficacy of motivational interviewing on decreasing male addicts’ high-risk sexual behaviors in Kermanshah. Methods The method was quasi-experimental with pretest-posttest and control group. The population of the study consisted of male addicts in Kermanshah. Three addiction treatment centers were selected by convenient sampling. The high-risk sexual behaviors questionnaire (Zarei et al. 2010), was given to participante. From whom; 71 persons achieved higher normal scores. 24 clients frome all participants went in two experimental and control groups with equal numbers (n = 12). Results Motivational interviewing was performed on the experimental group in the frame of 5 sessions .each lasted for 90 minutes. Post test was taken two weeks after the last session of the intervention. Data were analyzed using descriptive statistics (mean and standard deviation) and inferential statistics (covariance analysis). The results indicated a significant difference between the mean of high-risk sexual behaviors between experimental and control groups (p<0/05). Also results revealed that motivational interviewing is probably efficacious for reducing high-risk sexual behaviors among addicts Conclusion therefore this approach can be used in order to prevent HIV incidence through decreasing high-risk sexual behaviors in high-risk groups. Keywords Motivational Interviewing, High-risk Sexual Behaviors, HIV, Addicts. Effectiveness of Fara Roshd Training Program on Social Adjustment, Problem Solving Skills, Creative Thinking and Relaxation of Opioid-Dependent Patients Kiumars Arjomand Ghujur1, Mohammad Zavvar Chartagh2 1. Dehkhoda University of Applied Science and Technology of Tekab 2. Dehkhoda University of Applied Science and Technology of Tekab Background and Aim A multi-pronged psychological interventions can have positive effects on opioid-dependent patients. Present study aims to determine the effectiveness of Fara Roshd training program on social adjustment, problem solving skills, creative thinking and relaxation of opioid-dependent patients of town of Takab. Methods This study is a kind of clinical trial which its content of training program using external studies, for the first time was designed in Dehkhoda University of Applied Science and Technology of Tekab. The statistical population included all Opioid-dependent patients of town of Tekab in 1392 who referred to addiction treatment centers of this town and among them 40 cases were selected as samples using available sampling and were divided into two groups of experiment (20 subjects) and control (20 subjects). This study investigated the effects of a multi-pronged psychological training program for a period of two months (2 sessions per week) on the experimental group. Instruments include the Bell Adjustment inventory (BAI), Heppner and Petersen Problem Solving inventory (PSI), Torrance creativity test and researcher made questionnaire. To analyze the data, in addition to descriptive statistics, the analysis of variance test with repeated measure (ANCOVA) was used. Results The results showed there is significant difference between the experimental group and the control group, and the experimental group showed a higher level of social adjustment, problem solving skills, creative thinking and relaxation compared with the control group (P<0.001). Conclusion Fara Roshd training program is effective in raising the level of social adjustment, problem solving skills, creative thinking and relaxation of opioid-dependent patients and this training program can be used in treatment and rehabilitation centers in order to enhance the quality of life of drug-dependent patients and prevention of relapse in them. Keywords Fara Roshd Training Program, Social Adjustment, Problem Solving Skills, Creative Thinking, Relaxation S132 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Reproductive Health Status of Women Referring to Addiction Centers Under the Supervision of Urmia City’s Welfare Organization Zhaleh Zeinaly1, Parvin Mohammadpouri2, Zahra Amirkhanzadeh Barandouzi3, Mahnaz Mohammadpouri4, Zahra Ahmadnezhad5, Javid Behnam6, Iran Khalili7 1. Clinical Research Development Center, Motahari Teaching Hospital, Urmia University of Medical Science, Urmia, Iran 2. Prevention Department, Welfare Organization of West Azarbayjan, Urmia, Iran 3. Clinical Research Development Center, Motahari Teaching Hospital, Urmia University of Medical Science, Urmia, Iran 4. Clinical Research Development Center, Motahari Teaching Hospital, Urmia University of Medical Science, Urmia, Iran 5. Clinical Research Development Center, Motahari Teaching Hospital, Urmia University of Medical Science, Urmia, Iran 6. Clinical Research Development Center, Motahari Teaching Hospital, Urmia University of Medical Science, Urmia, Iran 7. Clinical Research Development Center, Motahari Teaching Hospital, Urmia University of Medical Science, Urmia, Iran Conclusion Considering to the high prevalence of drug abuse during pregnancy and its complications and the low average age at marriage and low education and the relative prevalence of risky sexual behaviors in this stratum of society, the need to give awareness and education on reproductive health issues and improve the quantity and quality of reproductive health services seem to be a necessity. Keywords Reproductive Health, Woman, Addiction Background and Aim Addiction is one of the major health, mental and social problems in the world and the main causes of the breaking up families and communities. According to a recent report by the Center for Combating Drugs, today, about 65 percent of addicts are married, leading to fourfold increasing addicted woman over the last ten years in Iran. According to statistics, 75% of addicted women are in fertility age and importance of reproductive health in providing family health, particularly in women and girls, the need to assess their health, is necessary. This study assesses the women’s reproductive health status referred to addiction treatment centers in Urmia city. Methods In this descriptive study the reproductive health status of women who admitted to addiction centers under Welfare Organization Urmia city, were evaluated. Sampling method was census so, all women in the reproductive age participated in the study. The questionnaire included demographic information, drug abuse, menstrual history, obstetric history used in this study. Validity and reliability of this instrument was determined by Content Validity Index and Inter Rater Reliability (r=0.95). Data were analyzed by SPSS version 20. Results undergone Pap smear screening test. Average age at first pregnancy was 19/68 ± 3/83 years, the average number of conceptions was 2/85 ± 1/61, 58/8% were terminated by NVD and 41/80% by C/S. In terms of pregnancy outcome, 35/2 % of pregnancies result in abortion, 20/6% of the preterm births, 16/8 % of infants born with low birth weight, 8/6% had abnormalities and 21/33 % of the births were stillbirths. Average age of women was 35/14± 1/55, mean of married age 17/91 ± 0/61 , the highest level of education, under diploma (58/8%), the first drug consumed by more women was opium (55/90%), the age range of onset of drug abuse, in most women was (35/30%) 15-20 years, and mean duration of methadone using in the more women (35/30%) was more than one year. The mean age of menarche was 13/23± 0/21 years, the mean duration of menstruation was 5/93 ± 0/24 days, and the average intervals between menstruation days was 26/13 ± 0/61. 84/4% of women had regular menstrual cycle, 67/5% of the women were suffering from moderate to severe dysmenorrhea, among them only 38/2% of women had used pain medication to relieve their dysmenorrhea. 57/6 % of those were sexually active apply one of the contraceptive methods, the most applied was LD (36/4 %). Among sexually active women 22/6 % had more than one sexual partner in the last two years, 44/1 % of sexually active women, who had Phosphodiesterase Inhibitor 4, Ibudilast, Can Control The Hippocampal Neurodegeneration Caused by Chronic Morphine Addiction. Mohsen Zhaleh1, Ghasem Saki2, Mehri Ghafourian Broojerdnia3, Rostam Ghorbani4 1. Department of Anatomy and Cell Biology, Paramedical Faculty, Kermanshah University of Medical Sciences, Kermanshah, Iran 2. Department of Anatomy and Cell Biology, Medicine Faculty, Ahvaz Jundishapur University of Medical Sciences, Kermanshah, Iran 3. Department of Immunology, Medicine Faculty, Ahvaz Jundishapur University of Medical Sciences, Kermanshah, Iran 4. Department of Anatomy and Cell Biology, Medicine Faculty, Kermanshah University of Medical Sciences, Kermanshah, Iran Background and Aim Following long-term administration of morphine, neurogenesis can be impaired and specifically decrease. Many researchers believe this is due to suppression of endogenous opioid system and overstimulation of classical opioid receptors, especially opioid receptor type Mu (MORs) by the morphine agonist drug receptor. And more detailed studies found that morphine can act as a ligand for a Toll-like Receptor type 4 (TLR4) and after stimulation of this receptor cause increase stimulation of innate immune system and increased levels of pro-inflammatory cytokines. This cytokines can disrupt their neurological environment situation and neurological degenerative process. This study was undertaken to determine whether chronic administration of morphine stimulates neuronal degeneration and whether that action dependent on TLR4 receptors in male rat hippocampus. Methods 32 mature male rats (200-250 gr) were randomly divided in four (n=8) group. All animals in the first 7 days, to intercept the newly divided cell immunohistochemistry, the intraperitoneal administration of di-BromodeoxiUridin (BrdU) were used. The groups are; Control: These animals were received in their drinking water at a rate of 4% sucrose. Morphine dependent: These animals were received morphine in the form of solution in the drinking water (maximum concentration 0.4 mgr/ml) with 4% sucrose for elimi- Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S133 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall nation of bitter and nasty taste. Coadministration of morphine and non-specific phosphodiesterase inhibitor drug, (Ibudilast): These animals in addition get the same morphine such as group B , as well as Ibudilast drug as inhibitor of TLR4 receptor stimulation effects, twice a day and the 10 mgr/kg/day by Intraperitoneal injection. Coadministration of morphine and non-reversible antagonist of Mu opioid receptor, (β-Funaltrxamine, β-FNA): These animals in addition get the same morphine such as group B, β-FNA drug also 20 mgr/kg by intraperitoneal injection of once every four days. After 30 days, the left hemisphere freezed and stored at -20 �. Then, on the basis of brain map Paksino, frozen serial sections were prepared for the immunohistochemistry experiments. Prepared slides were examined for presence and supply of specific protein and characteristics of each cell during neural differentiation (immature granular cells for the presence of Doublecorthin protein, mature granular cells for the presence of NeuN protein, mature astrocyte cells for the presence of S100-b) and also BrdU marker to identify newly divided cells by immunohistochemistry. After imaging, the number of positive cells were calculated from immunohistologic in three-dimensional and per unit volume specific in each of the groups under study. Results The results and statistical analysis showed that the greatest reduction in neurogenesis, including proliferation, differentiation and cell fate was in morphine-dependent group (Group B). This is a significant difference between the control group entirely (p<0.001). Co administration Ibudilast as TLR4 receptor inhibitors has been able to maintain control over the conditions of nerve regeneration. Effects of Mu opioid receptor blockade (MOR) by β-FNA is always weaker than the effect of the drug Ibudilast and the difference is quite significant (p<0.04). Conclusion Our results suggested that phosphodiesterase inhibitor drugs like as Ibudilast can be used for controlling and treatment of morphine-induced CNS degeneration. Keywords Hippocampus, Morphine, Ibudilast, Neurodegeneration, TLR4, BrdU. Capacity Building: a Model for Enhancing the Capabilities of Actors Involved in Community-Based Processes Seyed Babak Moosavi Nejad Baznegar Moaser Institute of Development Studies in Collaboration with Addiction Prevention Bureau of Welfare Organization Objective This article aims to present the case for implementing a capacity building programme in place of a conventional training programme. The advantages and effectiveness of the two approaches are therefore also compared. In spite of the long history of training in development, one of the more debatable topics has always been the effectiveness of training programmes. This has led to doubts regarding the trend and methods of training. In this article, it is explained that capacity building is more than mere training. Throughout the 90’s, capacity building came to be used as a comprehensive term to describe a sustained enhancement of the competency and problem-solving abilities of people and institutions. However, in order to be effective, a capacity building programme or process has pre-requisites. These are also assessed in this article. Methodology The capacity building programme implemented for the staff of addiction prevention bureau aimed to establish a learning approach amongst individuals and groups, so that they can gradually gain the capacity to learn from the diverse situations they find themselves in and to be able to plan for appropriate action. The basis for the capacity building programme was for the participants to reflect upon their own activities and to extract lessons and principles for their future activities. This six-month capacity building programme comprised of meetings, practical work and activities to be carried out in between the meetings. The intended methodology was experiential learning, an iterative and cyclic process of action-reflection-action. It was expected that after each experience the participants would be equipped with a new and more transparent perception of how to implement and support participatory and community-based processes in their own environments. Findings One of the more significant findings of this programme were the driving and prohibiting factors that affect the implementation of a capacity building programme. The participants’ understanding of these are touched upon in this article. In some of the provinces there was also an opportunity to evaluate the capacity building process in terms of its relevance to the participants real working environments, as well assessing the requirements of implementing a capacity building programme at community level. Conclusions The more the participants could work together as teams in their practical field work, the more it could be expected that the practical work be more multi-dimensional. Also, like any learning process, the speed, quality and lessons of a capacity building process depend to a great extent on the trust and motivation of the participants with respect to the process and the facilitating team. Finally, in terms of opportunities for joint learning, probably nothing can be as effective as the participants reflecting together on their practical field work. Reflection can be considered as the main component of a capacity building programme. A Study of the Characteristics of the Context and the Nature of Activities Conducive for a Community-Based Process (Based on the Experience of Five Provinces – Mazandaran, Zanjan, Hamedan, Alborz and Tehran) Shahryar Rahmani Baznegar Moaser Institute of Development Studies in Collaboration with Addiction Prevention Bureau of Welfare Organization S134 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Objective The bureau of addiction prevention of the Well-being Organisation started to adopt a community-based approach to addiction prevention in 2002, so that communities could begin to take the initiative and responsibility with respect to addiction prevention. There have been obstacles along the way, two reasons of which are examined in this article: (1) aiming to do community-based work in a context where a community – in the true sense of the word – does exist; and (2) the lack of coherence between the type of activities envisaged for community-based projects and the concepts and principles of a community-based approach (with a focus on educational and training activities). Methodology The approach to identifying and examining the obstacles to community-based work was group discussions - using participatory methods and techniques - with the implementing staff of the projects and assessing the obstacles with respect to the theory of community-based approaches. Findings An overall review of some of the community-based projects in the provinces has shown that these projects are often carried out in contexts where there are no communities, or the features expected in a community are very faint. In other words, situations in which it is claimed that community-based activities are taking place do not necessarily have in them the characteristics associated with the term ‘community’. To elaborate on the distinction between a community-based and classic/conventional approach to prevention programmes, this article takes a critical look at some of these project titles and asks whether the claimed community-based nature of a project should be reflected in its title. From another perspective, the type of activities that make up the main components of a project claiming to be community-based should also be different from those of a conventional approach. For example, in a conventional approach, it is normal for educational and informative activities to make up significant parts of the process. However, in a community-based approach, educational and training activities can not in themselves be considered as community-based. This article will shed light on why such projects should – at best – be seen as occasional inputs in bigger, more integrative and more people-centered process. Conclusions This article argues that if the advantages of adopting a community-based approach are to be realized, then it is important to implement the projects in a real community setting. That is why identifying a community by characteristics that are discussed in the article should be considered as one of the more significant steps in the early stages of a project cycle. As for the phenomenon of training, the article does not imply that there is no room for training or educational activities in a community-based process. What is important is that these trainings complement, and do not contradict, the community-based nature of the whole process and this applies to all the activities envisaged for a community-based process. The Efficacy of Cognitive-Behavioral Stress Management Training on Mental Health and the Sense of Group Therapy for Drug Abusers Ameneh Aalivand 1, Reza Zilabi2 1. MA in Clinical Psychology 2. General Medicine Objective The aim of this study was to evaluate the efficacy of cognitivebehavioral stress management training on mental health and the sense of group therapy for drug abusers. Method 36 Nfrazafrad rehab center in Ahwaz method selected and divided into two groups, training and monitoring. Findings Cognitive-behavioral stress management training and Mnadrmany a significant difference in promoting mental health and drug abusers has provided. Conclusion The results of the experiment showed that the training sessions, increasing mental health, drug abusers have been effective. Keywords Stress Management Training, Cognitive - Behavioral Group Therapy Concepts, Mental Health, Drug Abusers Factors Influencing the Orientation of the Drug in Poor Neighborhoods Narges Hedayati, Muhammad Baqrsfvt, Narges Hedayati Province Welfare - Department of Social Welfare Shiraz city Introduction “God and everyone else was the same place I was living in a ruined neighborhood like this, so she was addicted ...” The words and phrases like, most of the languages of many addicts to treatment centers for drug addiction Welfare (which constitute most impoverished neighborhoods inhabited the customers) are referred to, are heard. Methods The project is in the form ((case - control)) and research is a marginal population of the city neighborhoods, the Neighborhood ((ten cup), respectively).(non-addicted youth) and 30 controls (Youth Addict) were selected.Research tool to obtain demographic data (researcher) and then to reviews. (GHQ) mental health test. After data collection, using statistical methods to test the hypothesis whether Vmnadar scores in the two groups, are investigated. Research findings Based on the findings of the youth group (non-drug) compared Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S135 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall with other groups, have better academic achievement, in terms of employment status, working mainly in Vmshaghl service, shops, super mechanic, sometimes with military occupations or office. These Vghalba had more interest in the sport was a sport activity. Households in the experimental group than the control group, often between 4 and 6 Nfrbvdnd public health in the total test scores for this group over other groups. Discussion This research is based on 1 - ((proactive approach)) is a 2 - rather than the process (risk factors), 3 - (protective factors) note, Vlzatmrkzan not on the drug, the other drug, causes of its tendency to addiction is. 1-Preventive Approach 2-Risk factors 3-Protective factors To maintain control and discipline in the home, community and family values, respect for rules, carefully chosen friends and having more mental health, substance abuse prevention, have been effective in this area, but there are factors such as marital status and group Lack of family or addict, addiction does not show the little reluctance. Creating spaces and sports and recreational facilities, such as the employment of youth,)) and NGO) and 2 ((C.B1 (as is required in the form of long-term prevention programs such as Local, to provide training to strengthen (protective factors) Mzkvrv institutionalize their families should be paid. 1-Communty Base 2-Nongovernment organization Research conclusion It shows that all plans which are applied in order to prevention are as total Maximum agreements among responders who considered to community-based plans (64%) and after that other responses considered to comprehensive and focused plans based on giving information and awareness. Among aimed groups , people who have more influence on addicted and can prevent them are parents (75%) then friends (54%) which are really important and most of the responders are believed that among four prevention methods , it is better that needed budgets would be assigned to the hedging. Key Words Addiction, Prevention, Drug Abuse, Cultural Poverty, Ten Region of Tehran Recovery Based on Spirituality in Substance Abusers in Iran Abbas Shamsalina1, Kiyan Norouzi2, Masoud Fallahi Khoshknab3, Ali Farhoudian4 1- B.Sc. ,M.Sc. ,PhD Student, Nursing Department, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 2- Corresponding Author: PhD, Assistant Professor,,Nursing Department, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 3- PhD. Associate Professor, Nursing Department,University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 4- Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran Background Seyydeh Maryam Emamizadeh1, Hossein Aghajani Mersa2 1- Anthropology Science And Research Branch of Islamic Azad University of Tehran 2- Faculty Member of Azad University Background And Aim Addiction is one of problem in human society which is known as a biological psychological and social disease, we can see it around us seriously. Arising problems in families, society and increasing the amount of crime in the society, indicate the need for attention to this issue and also lack of attention to this social problem, lack of serious studying and pathological addiction , lack of cohesive and comprehensive plan all are as factors which led to growing addiction in the society. Since dealing with addiction problems requires substantial time and cost so prevention is much more effective rather than treatment and the most effective way for a health society is preventing the proliferation and drug distribution which is required to much more attention from responsible. General aim of this study is identifying effective ways in order to reducing addiction and prevention before treatment. Method of research In this study both quality and quantity methods are combined and needed information by using of questionnaire technique is collected and statistical population is composed of 40 peoples who are addicted and 20 people as experts of prevention offices in 10 region of Tehran are selected. One of the effective factors in the decrease of substance abuse severity and maintenance of recovery is spirituality. This research, investigates the effect of spiritual experience in the recovery of substance abusers. Methods This study used qualitative approach.16 men and 6 women were selected through purposeful sampling and with maximum variety from among both genders and from different recovery periods. Data were collected via semi-structured interviews. Results Data analysis two main categories:“Mutual relationship between spirituality and recovery” with the four subcategories of religious background, religious teachings, experience exchange and support by family and society, and “A new perspective toward life” with the two subcategories of access to calmness, and spiritual development. A repetitive code was named under the title of “spirituality meaning religion”. Conclusions The results of this study can be useful for the policy makers, care providers, families, and addicts. Promotion of spirituality in substance abusers for struggling with temptation, encouraging of substance abusers and their families to participate in spirituality-based psycho-therapy sessions held in addiction treatment centers, multi-disciplinary cooperation for completing the treatment programs among the organizations involved in addiction phenomenon, and training the families regarding the importance S136 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall of spirituality in the mental health of their children through the mass media are of the effective strategies for drug abstinence and maintaining of recovery. Keywords Recovery, Substance Abuse, Spirituality, Qualitative study Reflections of a Homeless Population’s Lived Experience With Substance Abuse Javadi .S. M.H1., Pilevari . A2., Hamed .,M3. 1- PHD Student in Social Work, Tehran Welfare and Rehabilitation University -javadismh4@gmail.com 2- PHD Student in Social Work, Tehran Alame University 3- PHD Student in Social Work, Tehran Alame University Background And Aim Substance abuse is recognized as a major health problem among the homeless. People who cycle in and out of homelessness tend to cycle in and out of alcohol and drug abuse. The relationship between substance abuse and homelessness requires that they are treated simultaneously and not independently. Although there is an increase in public interest concerning the homeless population, research on the issues of homelessness has been fragmented and incomplete. Research is necessary to understand substance abuse among the homeless so that prevention and intervention measures can be developed and implemented. The aim of this study was to describe a homeless population’s lived experience with substance abuse and to better understand factors that effect to substance abuse treatment among the homeless. Method of research This paper fulfilled by the method of grounded theory. The data were gathered through in-depth interviews with 20 men who participating in Project of rehabilitation of drug user (1393). Data from the interviews were analyzed by theoretical coding. Research conclusion Categories that emerged from the data included: experience of rejection from family and friends, traumatic experience, shame, social isolation, hopeless, social apathy. The core category in this investigation was “marginalization” of the homeless addict. Finally in this article we present a paradigm model of marginalization of these groups. Recognizing these categories can assist to effective planning, make policy and intervention on addiction and homeless. Key Words Lived Experience, Addiction, Homeless, Experience of Rejection CRF1 Receptor As a Novel Target for Substance Addiction Treatment Roshanak Mostofialmamaleki1, Javad Morabbi2 1- MS candidate in Cellular & Molecular Biology 2- MD, PhD Candidate in Addiction Studies Drug addiction has been conceptualized as a chronically relapsing disorder of compulsive drug seeking and taking that progresses through three stages: binge/intoxication, withdrawal/negative affect, and preoccupation/ anticipation. Drug addiction impacts multiple motivational mechanisms and can be conceptualized as a disorder that progresses from positive reinforcement (binge/intoxication stage) to negative reinforcement (withdrawal/negative affect stage). The construct of negative reinforcement is defined as drug taking that alleviates a negative emotional state.one hypothesis is that the negative emotional state that drives such negative reinforcement is derived from dysregulation of key neurochemical elements involved in the brain stress systems within the frontal cortex, ventral striatum, and extended amygdala. Specific neurochemical elements in these structures are CRF, Dynorphine and NE.Additionally, Excessive drug taking engages activation of CRF not only in the extended amygdala, accompanied by anxietylike states, but also in the medial prefrontal cortex, accompanied by deficits in executive function that may facilitate the transition to compulsive-like responding. both the HPA axis and extrahypothalamic CRFsystems are activated during acute withdrawal from all major drugs of abuse in animal models, and central infusion of non-peptide CRF antagonists block the anxiogenic-like responses observed during acute withdrawal from drugs of abuse, including cocaine, alcohol, nicotine and cannabinoids. Similarly, systemic administration of blood–brain-barrier-penetrating CRF1 antagonists reduced the anxiogenic-, aversive- and hypohedonic-like effects of withdrawal from opioids, nicotine, benzodiazepines and alcohol. Moreover, the decreased brain reward function associated with drug withdrawal is CRF1 receptor-dependent. Elevation of reward thresholds during nicotine withdrawal is blocked byCRF1 antagonists. As above evidences CRF1 receptore probabely is a novel target for substance addiction treatment. At the present time GlaxoSmithKline and NIH are collaboratively evaluating verucerfont(An Anti-CRF1) for its ability to reduce stress-induced alcohol craving in anxious, stress-reactive alcoholic women (NCT01187511). Similarly, a comprehensive collaboration of Bristol Myers Squibb and NIH is currently testing oral daily pexacerfont(An Anti-CRF1) for its efficacy to prevent: (1) stress-induced craving for palatable food in dieters (NCT01656577), (2) stress-induced craving for tobacco in smokers attempting to quit (NCT01557556), and (3) stress- or alcohol cue-induced craving in anxious, alcoholic women (NCT01227980). Drug Prevention History and Current Addiction Prevention Programs in Germany Juliet Roudini1 1- Leipzig University, Germany The presentation will focus on the addiction prevention in Germany over the last years and discuss the prevention programs of addiction in recent years.The prevention of addiction is together with addiction therapy and repressive actions – an integral part of the comprehensive addiction and drug policy of the Federal Republic of Germany. Apart from severe psychological and physical harm done to the individual, substance abuse and addiction also cause huge damage to the national economy. Prevention of addiction therefore assumes a central position in Germany. Prevention is one of the four main areas of German addiction and drug policy Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S137 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall is based on. Primary drug prevention in Germany has been in a constant state of transition since the early 1970s. Themain goal of prevention is to promote the health of the individual, maintain abstinence, prevent and decrease abuse and addiction. Five consecutive phases can be identified: (1) drug deterrence and repression; (2) drug education and drug information; (3) primary drug preventionthrough alternatives to risk-taking, and the strengthening of personal resources;(4) primary drug prevention through strengthening of personal and social resources,promotion of resistance and life skills; (5) primary drug prevention throughstrengthening of personal and social resources, promotion of resistance and lifeskills, the promotion of harm reduction and competence in risk-taking with young people who may already consume legal or illegal drugs. The second focus of the presentation is related to the currentaddiction prevention programs in Germany. With Germany’s history of beer brewing and pharmaceutical drug manufacturing, perhaps its current problems with substance abuse and addiction should come as no surprise.Drug prevention that systematically addresses the relevant target groups in their settings is particularly effective as regards achieving a health-promoting change in knowledge, attitudes and behavior. In this presentation we will investigate drug prevention programs in Germany for children and young people in the family, at school, community, and in their leisure time, and will be discussed about Dot.sys - Documentation system for drug prevention. Ecstasy- Induced Neurotoxicity Improves Following N-Acetylcysteine Administration Sara Soleimani Asl 1, Mehdi Mehdizadeh2 1- Research Center for Behavioral Disorders and Substance Abuse, Hamadan University of Medical Sciences, Hamadan, Iran. 2- Cellular and Molecular Research center, Faculty of Advanced Technologies in Medicine, Department of Anatomy, Iran University of Medical Sciences, Tehran, Iran Introduction Exposure to 3, 4-methylenedioxymethamphetamine (MDMA) can lead to spatial memory impairments and hippocampal cell death. Numerous evidence indicates that the antioxidant Nacetylcysteine (NAC) exerts protective effects in the brain. The present study evaluates the effects of NAC on MDMA-induced neurotoxicity. Methods We intraperitoneally injected 28 adult male Sprague-Dawley rats (200-250 g) with either 0, 10 mg/kg of MDMA, or 10 mg/ kg of MDMA plus 100 mg/kg of NAC. Spatial memory was assessed with a Morris Water Maze (MWM). At the end of the study, rats’ brains were removed to study the structure and ultrastructure of CA1, and measure Bcl-2 and Bax expressions in the hippocampus. Results rant in MDMA-treated animals was attenuated by NAC (p < 0.01). NAC significantly protected against MDMA-induced apoptosis and the up- and down-regulation of Bax and Bcl-2, respectively. Conclusion These data have suggested that NAC could protect against behavioral changes and apoptosis in the hippocampus following administration of MDMA. NAC might be useful for the treatment of neurotoxicity in MDMA users. A Review of Group Therapy in Drug Abuse Saeed Momtazi M.D. Zanjan Medical University and NIDA Research Fellow at UCLA Although group psychotherapy has been used for a variety of mental health problems, it is one of the most common and the most beneficial treatment modalities for drug abuse patients seeking treatment. Irvin Yalom, the most influential person in the field of group psychotherapy described 11 therapeutic factors that influence the processes of improvement and recovery among mental health clients. All of them are functional in drug abuse group therapy: 1. Instillation of hope – encouragement and acceptance that recovery is possible 2. Universality - feeling of having similar problems like other people 3. Imparting information - teaching about addiction processes and recovery 4. Altruism - supporting others in the process of recovery 5. Corrective recapitulation of family of origin – identifying and changing the dysfunctional roles that are played since childhood 6. Developing social skills - learning new ways to talk about feelings, observations and concerns and dealing with others in order to keep recovery 7. Imitative behavior – modeling others’ adaptive behavior and recovery skills 8. Interpersonal learning - finding out about their own and others experiences in the path of drug use recovery 9. Group cohesion - feeling of belonging to a group and being valued by others 10. Catharsis – release of emotional tension which can be related to drug use 11. Existential factors – addressing haman basic concerns like loneliness and death realities Different kinds of group psychotherapy are used for drug abuse clients. The most common treatment models include: 1. Psycho-educational groups 2. Skills development groups 3. Cognitive–behavioral/problem solving groups 4. Support groups 5. Interpersonal process groups 6. Relapse prevention groups 7. Expressive art therapy groups Each model or a combination of two or more modalities should be matched with the needs of different clients. In the MWM, NAC treatment significantly attenuated the MDMA-induced increase in distance traveled (p < 0.05) and escape latency (p < 0.001). The decreased time spent in the target quadS138 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall The First Step of the Program for the National Alcohol Service Providing in Iran Ali Farhoudian1, Alireza Noroozi2 1- Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 2- Head of Substance Abuse Prevention and Treatment Office (SAPTO), Ministry of Health, Tehran, Iran Iran has encountered an outbreak of alcohol use as well as alcohol use disorders these years. Alcohol was the first illicit substance which people have consumed during the last year. Although fortunately we have the chance of having more than 5300 substance use disorder treatment centers with educated staff that is a special opportunity to develop and implement alcohol treatment in the addiction program services. In this presentation we will talk about the inclusion criteria for recruiting volunteer physicians and psychologists, the criteria which a treatment center should own, and the supplementary educations a therapist should pass for fulfilling the criteria. Then, the method of this health system research will be discussed. A Review of Researches on Psychotherapy of Addiction in Iran; a 12-Year Evaluation Ebrahim Rezaei Dogaheh (PhD)1, Farima Anbari(MSc)2 1- Department of Clinical Psychology; Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 2- Department of Clinical Psychology; Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Ira The purpose of this study was to provide an overall perspective of researches on psychotherapy of addiction to identify the strengths and weaknesses. Using approved journals list of the Ministries of “Science, Research and Technology” and “Health and Medical Education”, the journals at the fields of addiction, behavioral science and psychology were identified. All scientific papers in the field of psychotherapy, substance abuse and dependence during a 12- year period beginning from 2003 to 2014 in national scientific journals were assessed. Then several variables including article information, scope and subject, methodology and location of publications were gathered. Research indicators were recorded in designed forms and finally analyzed using SPSS software. Keywords Addiction, Substance Abuse, Trend, Psychotherapy, Iran. Social Work Services for Women and Children in Substance Abuse Treatment and Harm Reduction Leila Arshad1 1- Sun House Society, Tehran, Iran More than 20% of substance abusers are women. The growing increase of substance abuse (especially methamphetamine use) by women and decreasing the average age of first substance abuse among them is a major health issue affecting women and families. Most of Women Substance Abusers (WSAs) hesitate to seek treatment and supports because of the stigma around using a substance and limitations of providing services for them. Social workers can markedly improve treatment and support services for WSAs and their children. Social workers in substance abuse treatment and harm reduction settings focus on providing special services for WSAs in case of pregnancy, sexual abuse, sex-working, child care giving, domestic violence, poverty, homelessness, etc. Keywords: Substance Abuse, Women, Child, Social Work Coping with Sress, Traumatic Experience and Disaster – The Role of Addiction and Specific Situations in Germany and South-East-Asia Evelin Witruk1 1- University of Leipzig, Germany Thepresentationwill focus on the addiction problems in Germany over the last years and discuss the psychological problems of addictionin the aftermath of traumatic experiences by natural disasters in South-East-Asia. On the basis of the psycho-biographical model of addiction,the following characteristics will be discussed: the degree of severity of drug problems (problematic use, abuse, addiction and dependency), the types of substances and non-substances which are used, the reasons or motivation for this abuse, the biographical background including the genetic factors, the living-, workingand family conditions and previous traumatic experiences as well as the physiological, psychological, and environmental consequences of the addiction, particularly the drug caused comorbidity, traffic accidents and criminal behavior. The both foci of the presentation will integrate research from two complete different territories, different cultural backgrounds, and reasons for addiction. First of them is the current situation in Germany and the second one is the addiction integrated into coping behaviorin the aftermath of natural disasters in South-EastAsia. The German drug report (2014) shows the predominance of Nicotine- and Alcohol abuse and addiction in comparison to illegal drugs such as Cannabis, Opium or Cocaine. The prevalence of alcohol problems in the adulthood can be predicted by the biographical onset of regular drinking and show an increase during the last five decades not only for men but also for women (Kraus et al., 2000). Among the illegal drugs, Opiates show the highest and increasing prevalence in adolescents and young adults (Perkonigg et al., 2004). Non-substance related addiction,particularly Internet-and Computer addiction, alsoincreased in German adolescents over the last years. The second focus of the presentation is related to the role of drug abuse and addiction in the context of coping with the experience of a natural disaster.One year after the earthquake on Java in 2006, we found a significant impact of psychological affectedness ondrug abuse as coping behavior (Witruk et al., 2014). In ourstudyregarding2 months, 1, 3 and 5 years after tsunami 2004 in Sri Lanka, we found in2007 and 2009 significant correlations between drug abuse included in an individual coping strategy an- Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S139 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall dgender, experience of the loss of home, the loss of job as well as the post-traumatic stress factor “Intrusions”(Witruk et al., 2009). The current findings show the complexity of relations between drug abuse and drug addiction and the biographical and environmental context.Moreover, traumatic experiences and chronic stress have special relevance.In this presentation, Escapism will be discussed as an important motivation for all kinds of abuse and addiction. Keywords Substance and Non-Substance Addiction, Legal and Illegal Drugs, Escapism as one of the Motives, Traumatic Experience. Addiction: A Choise or an Illness? Farbod Fadai Department of psychiatry, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran. Background and aim There are numerous debates and unanswered questions about the moral or criminal responsibilities in drug dependence. So, I decided to assess the various kinds of responsibilities in people with drug addiction. Methods Reviewing the related resources in medicine, social sciences, law, and philosophy Results There are two main points of view emong the thinkers. A group believe in free will of human beings and regard addiction as a personal choice. another group think that addiction is beyond the ideal concept of free will and see the people with addiction as patients who need treatment. Conclusion It seems that the truth lies beetween these two contradictory beliefs. Keywords Addiction, Responsibility, Illness Addiction in the Youth vs. Adults: How Different are They? Javad Alaghband rad, M.D. Tehran University of Medical Sciences Adolescence is a transitional developmental period in which enormous biological, cognitive and psychological changes occur. During this stage of ontogeny, however, substance use is commonly initiated. Among a fraction of users the consequences of consumption leads to problematic use or addiction. Typically, consumption begins with substances that are cheap and readily available. However, the particular drugs used and the pattern of progression are neither due to the pharmacological properties of the drugs nor constitute a developmental process. Rather, magnitude of individual predisposition in conjunction with opportunity to access a particular drug determine the outcomes. Age-related events such as disengagements from parental authority, socialisation, adult status (financial resources, independent transporta- tion), jaundiced view towards society, they all contribute to the outcome. In this presentation a conceptual model is described in which the interplay of liability- enhancing and liability- attenuating phenotypes interact with the environment during ontogeny. Psychiatric co morbidities are far more important than adults as will be described in this presentation. National Standards for Establishment of Inpatient Alcohol Treatment Programs: A Case of I. R of Iran Alireza Noroozi1, B RoshanaieMoghadam2, Ali Farhoudian3, N Beyraghi4, SV Shariat5, Jamal Shams6, A Hajebi7 1- Psychiatrist, Head of Substance Abuse Prevention and Treatment Office (SAPTO), Ministry of Health 2- Psychiatrist, Iranian National Center for Addiction Studies (INCAS), Tehran University of Medical Sciences (TUMS) 3- Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 4- Assistant Professor of Psychiatry, ShaheedBeheshti Medical University (SBMU) 5- ssociate Professor of Psychiatry, Iran University of Medical Sciences (IUMS) 6- Associate Professor of Psychiatry, ShaheedBeheshti Medical University (SBMU) 6- Assistant Professor of Psychiatry, Iran University of Medical Sciences (IUMS), Director General, Mental Health, Social Health and Addiction Department (MeHSHAHD) There is a total religious and legal ban on alcohol consumption in Iran, however in response to epidemiological data on alcohol use disorders and incidence of few cases of methanol intoxication mass epidemics in Iran, Ministry of Health and Ministry of Interior have formulated national policies on “Prevention, Tackle, Treatment, Harm Reduction and Rehabilitation of Alcohol Use” which were ratified in high rank national councils. One of the main strategic objectives of national policy document is to increase utilization of treatment, harm reduction and rehabilitation services in urban and rural areas. In order to develop standards of inpatient treatment models necessary to respond to alcohol treatment demand the MoH Alcohol Treatment Expert Group reviewed international evidence and guidelines and while considering context of addiction, psychiatric and health services in the country, suggest a two tiers approach including (i) low intensity inpatient care [medically managed residential services] and (ii) high intensity inpatient treatment services. To decrease cultural sensitivity and stigma attached to alcohol use from one hand and insufficiency of resources to develop new standalone programs on the other hand, MoH Alcohol Treatment Expert Grouprecommend to integrate alcohol programs within currently available network of inpatient psychiatric and health facilities. In this presentation the especial considerations to establish an inpatient alcohol treatment program are discussed. The suggested standards are going to be piloted in many private and governmental inpatient services and will be subject to further adjustments according to the results of pilot phase. Alcohol Screening Presentation in the Abstract Amir Ghanbari1 Aftabe Mehrvarzi Substance Abuse Treatment Center; Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran S140 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall An old adage about alcoholism is it’s “the only disease that denies it exists and resists treatment.” There are hundreds of alcohol screening tests available, including many detailed examinations with dozens of questions. In recent years, shorter tests have been developed to encourage screening for alcohol problems in urgent care centers and primary healthcare settings, which have been shown to be excellent opportunities to reduce harmful drinking with brief interventions. This presentation includes the Definition of Screening, it’s goals and it’s relation to the treatment plan and describes Different Types of Alcohol Screening Tests. Assessment of Sex Addiction There’s an ongoing debate in the psychiatric community about exactly how to define compulsive sexual behavior, because it’s not always easy to determine when normal sexual behavior crosses the line into problem sexual behavior. And also differential diagnosis with paraphilia, GID, hyper sexuality and… Assessments in this article is a reviewing of Drs. Pat Carnes and Ken Rosenberg that have 4 categories :Sexual Addiction Screening Test (SAST),The Ten Sexual Addiction Types Scales, Consequences Scales(Family/Friends, Financial/Business ,Legal and Preoccupation/Loss of Control) and Motivation for Change Scale . The Sexual Addiction Screening Test (SAST) is designed to assist in the assessment of sexually compulsive behavior which may indicate the presence of sex addiction. Developed in cooperation with hospitals, treatment programs, private therapists, and community groups, the SAST-R provides a profile of responses which help to discriminate between addictive and non-addictive behavior. Ten Sexual Addiction Types Scales(Fantasy Sex, Seductive Role Sex ,Voyeuristic Sex, Exhibitionistic Sex, Paying for Sex, Trading Sex, Intrusive Sex Anonymous Sex, Pain Exchange Sex, Exploitive Sex).after assessment a report with stratification help therapist for management. and messages that encourage non-use. ATS clearly represent a considerable cost and range of harm to individuals, families and communities. Prevention must be a central part of a response to ATS use problems because the other options cannot, in themselves, be expected to address these problems fully. A general drug prevention strategy cannot be expected to address ATS concerns without additional specific attention. An adaptation of prevention research points to the principles outlined below: Locate the amphetamine-type stimulant use prevention plan within a larger drug strategy and youth development frameworks; Base the prevention plan on a clear knowledge of the amphetamine type stimulant use problem and the resources that can be applied to it; Clarify the targets of amphetamine-type stimulant use prevention; Engage the youth target group meaningfully in policy and programme design and implementation; Strive for a comprehensive, coordinated response Choose programmes that are proven or show promise Ensure that activities are evaluated Pay attention to workforce development and organizational capacity No drug group has grown in use as ATS have in the past 15 years and there is a range of harm associated with their use. Problematic youthful ATS use can take a great toll on the young person and those who are close to them. It can also result in long-term social welfare, criminal justice, health and lost productivity costs to the community. Consequently, while addressing ATS-specific concerns, it is important to build infrastructure for the prevention of all substances. If that infrastructure does not currently exist in a community, a comprehensive, sustained approach to addressing ATS use— while effective in preventing or delaying ATS use— will also be a step in the direction of building capacity for substance use prevention generally. When this happens, the benefits to individuals, families and communities will be substantial. Keywords Sex Addiction. Assesment, Sexual Addiction Screening Test (SAST), Amphetamine Type Stimulant (ATS) Use Prevention Programmes in the World and Iran Hamidreza Taherinakhost1 1- National Programme Manager, United Nations Office on Drugs and Crime (UNODC), Country Office of Iran, hamid.taherinakhost@unodc.org Abstract A specific focus on ATS is necessary in many countries and communities because of their prevalence, the culture of hazardous use within some populations and the significant harm associated with these substances. There is currently a gap in the knowledge on how to prevent or delay use of ATS among young people. In any population of young people, whether among the mainstream of society or not, there is a large portion of individuals that are not using ATS, or are using them experimentally, and who would benefit from measures Person Centered Care: A Key Concept in Treatment for ATS Users Over the past 25 years, efforts to find effective treatments for ATS use have been extensive. Strategies have been adapted from the psychology-behavior therapy literature (CBT, Motivational Interviewing, Contingency Management, Matrix Model). A major effort has been conducted to discover medications that have efficacy for treating ATS users. Public health/harm reduction strategies have been devised and delivered to reduce the morbidity and mortality associated with ATS use. While no medications have been proven efficacious, several of the behavioral treatments are considered “evidence-based” and harm reduction efforts have been widely implemented in areas with heavy ATS use. As a result of all of these efforts, a variety of services now exist for ATS users in many parts of the world. In many of these efforts (at least in the United States) the development of the services have often involved extensive literature review, expert consultations, technical assistance and major (and in some cases, expensive) training programs. However, one critically important group has Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S141 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall often been overlooked as an essential and arguably the most important source of information for developing ATS services……. ATS users themselves. This step, of carefully and extensively assessing what the ATS users want as “help” or “treatment” or “low threshold” services is often overlooked. Efforts to collect this information using surveys and focus groups are important and useful first steps, but they are just first steps. There is a diversity of patient perspectives and priorities on this issue and the perspective and priorities change over time. As ATS treatment/harm reduction strategies are implemented, it is critically important to collect data on the patients’ perspectives on these approaches and helping strategies. Of course surveys, feedback questionnaires and focus groups are useful, but additionally, a critical measure is: When strategy X is implemented, do patients return to receive more of strategy X? When patients return over time, do their perspectives and priorities change? Do they like the service to be “as needed” or would they like a schedule of activities? Would they like some type of curriculum and/or information? On what topics? If they are attempting to reduce or abstain from use, and they relapse, is there any way that treatment could help them avoid relapse in the future. In our efforts to implement evidence-based treatment and harm reduction methods, we may forget the essential step of talking with the patients; their perspective and their priorities are essential to the success of any helping effort. programme design and implementation; Strive for a comprehensive, coordinated response Choose programmes that are proven or show promise Ensure that activities are evaluated Pay attention to workforce development and organizational capacity No drug group has grown in use as ATS have in the past 15 years and there is a range of harm associated with their use. Problematic youthful ATS use can take a great toll on the young person and those who are close to them. It can also result in long-term social welfare, criminal justice, health and lost productivity costs to the community. Consequently, while addressing ATS-specific concerns, it is important to build infrastructure for the prevention of all substances. If that infrastructure does not currently exist in a community, a comprehensive, sustained approach to addressing ATS use— while effective in preventing or delaying ATS use— will also be a step in the direction of building capacity for substance use prevention generally. When this happens, the benefits to individuals, families and communities will be substantial. Proven and promising universal and selective ATS use prevention programmes Amphetamine Type Stimulant (ATS) Use Prevention Programmes in the World and Iran Hamidreza Taherinakhost1 1- National Programme Manager, United Nations Office on Drugs and Crime (UNODC), Country Office of Iran, hamid.taherinakhost@unodc.org Abstract A specific focus on ATS is necessary in many countries and communities because of their prevalence, the culture of hazardous use within some populations and the significant harm associated with these substances. There is currently a gap in the knowledge on how to prevent or delay use of ATS among young people. In any population of young people, whether among the mainstream of society or not, there is a large portion of individuals that are not using ATS, or are using them experimentally, and who would benefit from measures and messages that encourage non-use. ATS clearly represent a considerable cost and range of harm to individuals, families and communities. Prevention must be a central part of a response to ATS use problems because the other options cannot, in themselves, be expected to address these problems fully. A general drug prevention strategy cannot be expected to address ATS concerns without additional specific attention. An adaptation of prevention research points to the principles outlined below: Locate the amphetamine-type stimulant use prevention plan within a larger drug strategy and youth development frameworks; Base the prevention plan on a clear knowledge of the amphetamine type stimulant use problem and the resources that can be applied to it; Clarify the targets of amphetamine-type stimulant use prevention; Engage the youth target group meaningfully in policy and Universal prevention Communication methods These messages can be delivered through a number of avenues, but the most common are the media (Internet, television, comics, etc.), peers, parents, dance clubs and youth mediators (for example, disc jockeys, recreation leaders, coaches and teachers). Combining several of these avenues helps to reinforce the messages, maximize exposure and increase effectiveness. World Practices: Meth Project, … Iran Practices: State Welfare Organization Meth Prevention Campaign School-based skill building models Based on a review of school programmes that rigorous evaluation has shown to be effective in preventing substance abuse, an intensity of one session per week over 10 weeks could be suggested as the minimum to produce results in school programmes. Sometimes this is simply not possible, so between three and five “booster” sessions in years that follow an initial 10-session programme to reinforce earlier lessons help to sustain effects. To be effective, school-based programmes need to combine elements of knowledge and skill development. World Practices: UpFront program operating in Oakland, CA, Life Skills Training Programme, Unplugged, & Party Drugs, … S142 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Iran Practices: Ministry of Education Life Skills Training (LST) Programme, Strengthening Schools, & Families and Schools Together (FAST) World Practices: In the United States, the Fast Track project, … Iran Practices: Families and Schools Together (FAST), Programme for Street Children The alternatives approach The alternatives approach is a commonly used prevention strategy. Although there is little research to support this approach at this point, it has an appealing logic to it: if they are involved in other satisfying activities, young people are less likely to use substances. Moreover, substance use is an important avenue for socializing, so those who choose not to use substances need other opportunities to make and build friendships. There is some indication that youth who are attracted to ATS use are sensation seeking; it would therefore make sense to work with young people to design activities that appeal to this need (for example, outdoor adventure or extreme sports). In other cases, there may simply be a need for a place to meet and belong to, such as club houses, chill-out cafés and Internet cafés. World Practices: Stockholm’s “Clubs Against Drugs” Project, Australia, drug-free dance parties, … Iran Practices: University of Tehran, Annual Tour for Freshmen (Dizin), Family programming for higher risk families It appears that “family-based” interventions are more effective than “parent-only” programming in building protective factors. Research has found that even relatively brief (five to seven sessions) family programmes that address communication, coping and disciplinary skills can be effective in delaying the onset of substance use among adolescents in at-risk families, compared with a comparison group after a four year follow-up World Practices: The Strengthening Families Program (SFP), FAST, … Iran Practices: Parenting, FAST, SFP 6-11, Healthy Youth Policy-based or environmental approaches Some public health experts contend the nightclub industry has a responsibility to contribute to the healthy socialization of young people because it looms so large in their lives and because other institutions (for example, the family and religious institutions) are now less influential with youth. By developing a firm policy against use of illegal substances, including ATS, on premises and training staff to identify drug use and exchanges, it is possible to reduce use by both guests and staff in these venues. We must remember, however, that such initiatives work only when there is a minimum critical mass of very popular venues participating in the campaign. Training staff from one or two out-of-the-way clubs will not have any impact at all. World Practices: Shawnee County Meth Awareness Project, North Coastal Prevention Coalition, Hood River County Alcohol Tobacco And Other Drug Prevention Coalition, Salt Lake City Mayor’s Coalition on Alcohol Tobacco and Other Drugs, … Iran Practices: Some Parenting Programmes !!? Selective prevention Selective prevention aims to build protective factors among young people exposed to one or more risk factors. Selective prevention programming that has multiple, integrated elements involving more than a single domain (such as the family, school or community), is more likely to have positive results than standalone interventions. Several selective prevention measures have been shown to prevent or delay use of substances (including ATS use) and are briefly described below. Early childhood and early school interventions Children living in difficult environments clearly benefit from selective prevention interventions in their pre-school (age 0-6) and early school (age 7-12) years. Programmes that combine child and parent components (often including home visits) have shown benefits in preventing a number of later behaviours—including substance use—in long-term studies at both the early childhood and early school period. School connection programmes School programmes that select at-risk young people (those who are not succeeding in school, have few peer contacts or are not involved in extra-curricular activities, for example) have proven effective in re-engaging students and reducing the risk of substance use. World Practices: The Reconnecting Youth programme, … Iran Practices: Parenting, FAST, SFP 6-11, Healthy Youth Outreach approaches The most vulnerable young people are often hard to reach, particularly if they no longer attend school. Outreach services are often necessary to reach and engage these young people. Accordingly, programmes for vulnerable youth may be situated in shopping malls, in hospital emergency wards, or in one-stop service centres on the street. World Practices: The MPowerment programme, … Iran Practices: Programme for Street Children Brief Motivational Home-Based Social Work Intervention Morteza Danaei Far Department of Social Work, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran Despite all the problems addiction causes for drug addicts and their families, less than 10% of addicts are volunteer for treatment. A qualitative study was conducted to design a Brief Motivational Home-Based Social Work Intervention to enhance drug abuse treatment entry rates and outcomes. Data was collected with semi-structured interviews with social workers who are working in drug abuse treatment setting. Interviews were recorded, transcribed and coded thematically and interventions were categorized. The Brief Motivational Home-Based Social Work Intervention was extracted according to the social work literature and proposed interventions. Social workers revised and finalized intervention (including family members awareness raising and preparation, motivational interviews at home, referring and following up) in focus group discussions. Keywords Home Based Social Work, Motivational Intervention, Drug Abuse Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S143 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Overview of Child Abuse and Neglect in Family with Drugs Abusers Asghar dalvandi1, Saeideh Bahrampuri2, Fatemeh Pashaei Sabet3 1- PhD in Healthy Ageing, Nursing Department, University of Social Welfare & Rehabilitation Sciences, Tehran, Iran 2- PhD student of health in disaster and emergency , University of Social Welfare & Rehabilitation Sciences, Tehran, Iran. 3- PhD student of Nursing in Nursing Department, University of Social Welfare & Rehabilitation Sciences,Tehran, Iran Introduction Addiction is one of the main social, psychological and health problems in recent century. The physical, emotional and social addiction’s aspects affect both the addicted person and the family and society itself. pesons are social creature and baby’s first communication to take place within family environment. Therefore family would play a significant contribution in the socialize children and shaping social behavior. Drug abuse by parents anxious incident that disrupted the balance of family and other members of the family responsibilities and roles affected parents are addicts. On the other hand, parental substance abuse, social constraints and reducing operating systems support for the children. This paper aims to present an overview Child Abuse and Neglect in Family with Drugs Abusers as a social problem. Content Child abuse and neglect are social and public health problems, as well as that considered the issue of children’s rights in any country. Abuse and neglect can be caused a wide range of negative outcomes for children and teenager in addict’s families (family lead addicts). Subgroup of child abuse and neglect in addict’s families can be noted physical, emotional and sexual abuse, neglect, and violence in the family and also forcing them to sell drugs. This reviews article explains the effects of parent’s addiction problem on child abuse and neglect, in the various types of abuse in childhood and adolescence, associated with certain adverse. Therefore, it seems to explain problems of children who have substance abuse dependent fathers could indicate their unhealthy and difficult life to authorities, their daily life. Contingency Management (CM) is a systematic use of reinforcement of desired behaviors in the treatment of alcohol and other drug use disorders. It encourages positive behavior change in patients. Most of the researches support CM’s efficacy in treating various behavioral disorders, including drug abuse treatment. Social workers apply CM techniques to reward positive behaviors by reinforcing consequences when patients meet treatment goals and or providing punitive measure when patients engage in the undesired behaviors. For example, positive consequences for abstinence may include receipt of vouchers that are exchangeable for retail goods, whereas negative consequences for drug abuse may include withholding of vouchers. Keywords Contingency Management, Social Work Addiction Monitoring, A Brief Review Abstract Hobbies are hobbybecausetheyhadthepower to attractpeople to them, but as theseattractionsbecomesmore, andthepeopleare interestedmore, the pathologic phenomenonarisesknown as behavioral addiction. Monitoraddiction in theforms of activeandpassive are among one of the behavioral addictionssuch as gamblingandshoppingorsexaddiction. Asthemonitorprogramsdevelopedmany subcategories especially in thedomain ofactivemonitoraddictionraised, such as computeraddiction, Internet addiction, cyber-sex addiction, etc. This article is trying to give a briefreview of thehistory, trend, terminologyandresearchdomains that could be feasibleaccording to the Iran situation as a developingcountry. Keywords Monitor Addiction. Internet Addiction, Computer Addiction, Sex Addiction Treatment: a Task-Based Approach Conclusion Therefore, it seems to explain problems of children who have substance abuse dependent fathers could indicate their unhealthy and difficult life to authorities, planners and researchers and also provide a wider vision than the problems these children face in their daily life. Here the present review article is done with our current identifying community needs and the necessity of providing appropriate services to these children. Keywords Child Abuse Neglect, Family Addiction, Social Problem Contingency Management in Social Support Zahra Saberi Prevention Deputy, Drug Prevention Office, State Welfare Organization, Tehran, Iran Abstract sex addiction is the use of sex or pornography to address nonsexual emotional needs. Sex addiction is relatively common behavioral addiction. Treatment for compulsive sexual behavior typically involves psychotherapy(Individual Therapy ,Group Therapy, Family Participation ,Family Recovery, Couples Recovery ,Exercise/Nutrition) medications and self-help groups. Certain medications may be helpful like Antidepressants,Mood stabilizers,Naltrexone,Anti-androgens, and (LHRH)But best treatment is Task-Based approach.that contain three phase First phase(Recovery Start) is about intervening in the cyclical compulsiveprocess The therapist must extend the patient’s sexual history to include all aspectsof the problematic behavior.During the initial phase of treatment, therapy focuses on teaching the patientabout the illness. In addition to coaching from the therapist, the patient must readand learn about the problem. The next section provides a list of resources wherepatients can obtain such information, refer the patient to a local 12-step group for sex addiction or sexual compulsion, start confronting areas of significant S144 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall denial in the patient, patient agreement to report any problems. Second phase(Creating Personal Recovery) of treatment can begin (during the first 4 to 8 weeksof treatment) 12-Step attendance, Complete first step of 12-step process, Agree on writing an abstinence definition, Written relapse-prevention plan, Complete period of celibacy, Develop a sex plan, Partner and family involvement, Multiple addiction assessment,Trauma assessment, Group therapy, Shame reduction Once a period of relapse-free behavior has taken place, Third phase(Creating Family Recovery) of treatment may begin. This phase focuses on underlying developmental issues and family-of-origin issues, Grief resolution ,Marital and family therapy, Career issues, Trauma therapy . behavioral addictions in the proposed categorization scheme A number of experts have argued that the concept of addiction will expand to four category : Substances (e.g. alcohol, street drugs, food, tobacco/nicotine, pharmaceuticals, etc.) Activities (e.g. work, sex, gambling, exercise, worship, cleaning, etc.) Relationships (i.e. codependency) Mind/body states (e.g. anger, arousal, histrionics, etc.) This new approach said that addictive behaviors relations are more than coexist, they interact, reinforce, become part of one another. They become packages. Keywords Addiction Interaction Disorder, Addiction and Related Disorders Keywords Sex Addiction Treatment, Task-Based Approach An Introduction to Multiple Addictions: Addiction Interaction Disorder RabertFarnam Psychiatrist Abstract With the new edition of the DSM, the revised category of“Substance-Related and Addictive Disorders” moves beyond a focus onwithdrawal and tolerance (i.e., classical dependence symptoms),towards the strength of motivation for substance use and engagementin behavior as well as the lack of control to resist craving. This reconceptualization allows for the inclusion of both,substance-related as well as behavioral addictions in the proposedcategorization scheme. A number of experts have argued that the concept of addiction will expand to four categories: Substances (e.g. alcohol, street drugs, food, tobacco/nicotine, pharmaceuticals, etc.), activities (e.g. work, sex, gambling, exercise, worship, cleaning, etc.), relationships (i.e. codependency, love addiction, traumatic bonding, etc.) and mind/body states (e.g. anger, arousal, histrionics, etc.). This new approach said that addictive behaviors relations are more than coexist, they interact, reinforce, become part of one another. They become packages. Understanding addiction interaction disorder could help addiction therapists to understand changing patterns of addictions during the treatment and could help them to develop more appropriate treatment plan addressing complexity of the multiple addiction within a client. Seyed Ramin Radfar1 1- Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran Amphetamine-type Stimulants (ATS) are known as one of the most important stimulants of abuse in the world with an increasing trend, so much that currently amphetamines are ranked second after cannabis as the most abused drug in the world. In recent years, the rate of stimulant use has grown dramatically, and such drugs are getting to a significant level that they are changing the old traditional pattern of addiction in Iran, In the other hand, the amount of seized ATS in Iran highly increased in recent years while Prior to 2004 there were no reported seizures of ATS in Iran and the first reported of ATS seizure was in 2005 but in less than 5 years an increasing number of seizures reported in Iran. The amount of methamphetamine seized qualified Iran for ranking 5th in ATS seizures in 2010 and 2011 . Comparing the ratio of seized ATS in each year shows a 400% increase in the amount of ATS seized in Iran between 2010 and 2011, this oneyear rate of increase compares to increases of 238% in Mexico 166% in Thailand, 153% in USA (153%) and 140% in China, puts Iran in the first ranking for increase in seizure. Some very recent studies show that the prevalence of ATS use among people who injects drug is almost equal to prevalence of opium use with a long history in Iran. This article is trying to follow trend of ATS use prevalence and changes in the pattern by a desk review from the available documents. Keywords Keywords Addiction Interaction Disorder,Addiction and Related Disorders Addiction Interaction Disorder Abstract Trend of ATS Abuse among Iranian Drug Users, a Decade Follow up With the new edition of the DSM, the revised category of “Addiction and Related Disorders” moves beyond a focus on withdrawal and tolerance (i.e., classical dependence symptoms), towards the strength of motivation for substance use and engagement in behavior as well as the lack of control to resist craving. this reconceptualization allows for the inclusion of both, substance-related as well as Amphetamine Type Stimulants, ATS, Methamphetamine, Iran Latent Tuberculosis (TB) Prevalence and Challenges for Integration of TB Diagnosis and Treatment programs in Harm Reduction activities in Iran Seyed Ramin Radfar1 ,Alireza Noroozi, Katayoun Tayeri, Abbas Motavalian, Pardis Nematollahi, Setareh Mohsenifar 1- Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S145 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Background Injecting Drug Users (IDUs) are one of the most at risk groups for HIV and other blood born infectious disease. Tuberculosis (TB) is another infection which could be spread out from this group to the other part of the community through daily contacts. LTBI situation with or without HIV among IDUs is important for designing better harm reduction services in Iran for providing better services for both IDUs /DUs and community. But the problem is that merging holistic TB services in harm reduction services is not easy due to many factors that some of them will be described later in this article. Methods This is a cross-sectional survey with laboratory and/or radiologic tests, has been conducted in Tehran, Isfahan, Mashhad, Shiraz, Gorgan and Kermanshah in Iran in 2013. Cities has been selected by joint committee of United Nation Office on Drug and Crime in Iran (UNODC), Drug Control Head Quarter (DCHQ) and Center for Disease Control at Ministry of Health (CDC) as the supporters of the study .Participants were active (had injection in past month) and recent (had injection in past 6 months) IDUs receiving services from drop in centers recruited by convenient sampling. The second part that is describing challenges for merging TB services in the harm reduction services that are mainly taken from a roundtable report that conducted by United Nations Office on Drugs and Crime office in Tehran in the current year with this topic. Results 420 IDUs (97.4% Male,2.6% Female) interviewed and checked for tuberculin skin test and HIV test and then based on selection criteria’s chest X-ray and sputum smear has been requested for 190 (45.2%)of them. HIV / PPD results are available for 99.3% and 94.8% of participants, respectively. HIV prevalence was 8.6% (0 to 18% in different cities; overall 9.1% of females, 8.6% males) and average positive tuberculin test was 35.7% (14.3% to 67.1% in different cities; overall 54.5% of females, 35.1% of males) of study participants. Odds ratio for positive tuberculin test calculated 3 (1.5<CI<6.4) in HIV positive IDUs comparing to HIV negative participants. PPD negative participants were younger than PPD positive (P value<0.04) but age difference for HIV positive VS negative participants were insignificant. All of the smear test were negative but radiologic findings were seen in 14.5% of patients with Chest X-ray. Conclusion Latent TB is very common among Iranian IDUs and the participants’ knowledge and information regarding TB is very low, therefore harm reduction programs should consider TB as one of the priorities in the current harm reduction services. Among the activities in the field of TB prevention, diagnosis and treatment in this group, the hardest feasible activity is treatment, because of the nature of the effective TB treatment and in the other hand the poor adherence of drug users for TB treatment regimens which can potentially result multi-drug resistant TB. Ethnography as Applied Research Method in Explaining and Understanding the Phenomena of Substance Abusers Recovery Asghar Dalvandi1, Saeideh Bahrampuri2 1- PhD in Healthy Ageing, Nursing Department, University of Social Welfare & Rehabilitation Sciences, Tehran, Iran Fatemeh Pashaei Sabet: PhD Student of Nursing in Nursing Department, University of Social Welfare & Rehabilitation Sciences,Tehran, Iran 2- PhD Student of Health in Disaster and Emergency, University of Social Welfare & Rehabilitation Sciences, Tehran, Iran. Introduction Ethnography is a written description of a particular culture, customs, beliefs and behavior, based on the information collected through the fieldwork. In this study, the researchers using the observation with the participation of, the subjects in an absolutely natural and free chats with them .According to assumptions of study, the individual’s behavior in groups are affected by a complex interaction which that has elements more than facts, statistics and evidence sums, as well as the behavior of individuals directly affected by the situation in which the behavior occurs placed.. The main objects of Ethnography is understand about values and beliefs of the people rounding in a social phenomenon like addiction and inform from their behavior through observation and participation in a selected social context, such as drug addiction. In this way, participants are enabling researchers to take an active role in public life with minimal disruption to the normal flow of social life on it the cortex to detect and help to explain the phenomenon of interaction and behavior of addicted peaple . Therefore, this paper introduces Ethnography as applied research method in explaining and understanding the phenomena of substance abusers recovery. Content Today, addiction as a health, social, and cultural have been facing all countries. The phenomenon of drug addiction is a multifaceted nature and rapid and/or privacy changes, therefore its need to comprehensive, accurate and also fast and dynamic interventions. In addition, the basis for policy-making, planning and selection of the proper procedures for drug abuse rehab is detailed knowledge of the information and the process of establishing terms and conditions governing the people involved with the quest for this phenomenon. Conclusion The experiences of researchers expressing, the surface review of this complex issue and inattention to deep cultural layers around behavior and interactions created in drug abuse is one of the causes of past failure in achieving comprehensive rehabilitation programs and the prevention of drug consumption, respectively. Keywords Ethnography Research, Abusers Recovery Keywords Tuberculosis, HIV, Injecting Drug Users, Iran, Multi-Drug Resistant TB S146 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 Qualitative Approach, , Substance The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Family –Based Intervention in Substance Abuse Treatment and Harm Reduction: A Systematic Review Masoomeh Maarefvand Department of Social Work, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran Little evidence exists regarding the Family Based Social Work Interventions (FBSWIs) in substance abuse treatment and harm reduction settings. In this study, FBSWIs in substance abuse treatment and harm reduction standards, protocols and programs reviewed systematically. Electronic search of SAMHSA, NIDA and NASW databases with no limits to publication year was conducted to find proposed FBSWIs. Social worker as a case manager could provide various FBSWIs including family support (i.e. meeting basic needs and conditional supports), child protection, family group conferencing, domestic violence intervention, family therapy and family training were the most important suggested FBSWIs. Keywords Family –Based Intervention, Substance Abuse, Social Work Conclusion Methamphetamine use among patientsundergoing methadone treatmentprograms in Iran is verycommonand could reverseorwastessome of theresources that are spendingfor HIV epidemic. Phenomenology of methamphetamine use among MMTpatients based on thefindings of thisstudy could be described as thatsomepatientswho are going to startMMT, alreadyhadpositiveattitude and/or experience of methamphetamine, ifthesepatientshad not thissituation a peergroup of theotherpatients and/ or friends/ families recommend them to use methamphetamine forreducingsideeffects of methadone that are prominentespecially in theinductionphase of methadone. Drug Prevention History and Current Addiction Prevention Programs in Germany Juliet Roudini1 1- Leipzig University, Germany Phenomenology of Methamphetamine Abuse Among Patients Undergoing Methadone Maintenance Treatment Background Formal data shows that annually about 500,000 patientsregisteredforOSTtreatment in Iran. Stimulant use among patients under OST potentially can wasteparts of thehugeresources which spentfor HIV/AIDS prevention. Thepurpose of thestudy is to explorefactorsandmechanismassociated with methamphetamine use among patientsundergoing methadone maintenancetreatment. Thisstudy is approved by boththe University of California at Los Angeles (UCLA) Human Subjects’ committeeandthe Tehran University of Medical Science Ethics Committee and is part of an IAS/NIDA-funded fellowship at UCLA Integrated Substance Abuse Programs. Method This qualitative studywasconductedusingfocusgroupdiscussion (FGD) in Isfahan, Iran, within varyingsettings of private, governmental, drop in centersandwomenfriendlyfacilities. Thematic analysis was conductedusing a thematic approach by ATLAS.tiversion 6.0.15. Results continue methamphetamine during MMTbecausethis two drug are verymatched with eachotherwhile methamphetamine and/or methadone are not matched with other opioids such as heroin oropium.Positive attitude toward methamphetamine Methadone cons, Methamphetamine pros and cons were extracted as the most important factor for methamphetamine abuse. Totally 7 FGDs (two for female participants and 5 for male participants) conducted between December 2013 and February 2014. Findings from eachsectorandgenderdid not showmajorvariation in participantperceptions. All of themaleandmajority of femaleparticipantsexpressedthat methamphetamine use among MMTpatients is verycommon, near half of them expressedthatmany of patients before to startMMTalreadydecided to use/ The presentation will focus on the addiction prevention in Germany over the last years and discuss the prevention programs of addiction in recent years.The prevention of addiction is together with addiction therapy and repressive actions – an integral part of the comprehensive addiction and drug policy of the Federal Republic of Germany. Apart from severe psychological and physical harm done to the individual, substance abuse and addiction also cause huge damage to the national economy. Prevention of addiction therefore assumes a central position in Germany. Prevention is one of the four main areas of German addiction and drug policy is based on. Primary drug prevention in Germany has been in a constant state of transition since the early 1970s. Themain goal of prevention is to promote the health of the individual, maintain abstinence, prevent and decrease abuse and addiction. Five consecutive phases can be identified: (1) drug deterrence and repression; (2) drug education and drug information; (3) primary drug preventionthrough alternatives to risk-taking, and the strengthening of personal resources;(4) primary drug prevention through strengthening of personal and social resources,promotion of resistance and life skills; (5) primary drug prevention throughstrengthening of personal and social resources, promotion of resistance and lifeskills, the promotion of harm reduction and competence in risk-taking with young people who may already consume legal or illegal drugs. The second focus of the presentation is related to the currentaddiction prevention programs in Germany. With Germany’s history of beer brewing and pharmaceutical drug manufacturing, perhaps its current problems with substance abuse and addiction should come as no surprise.Drug prevention that systematically addresses the relevant target groups in their settings is particularly effective as regards achieving a health-promoting change in knowledge, attitudes and behavior. In this presentation we will investigate drug prevention programs in Germany for children and young people Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S147 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall in the family, at school, community, and in their leisure time, and will be discussed about Dot.sys - Documentation system for drug prevention. Study on Situation of HIV, Latent Tuberculosis Infectious (LTBI) and Active TB Infection among Injecting Drug Users Receiving Harm Reduction Services in Tehran and 5 large cities in Iran Seyed Ramin Radfar1, Alireza Noroozi2, Katayoun Tayeri3, Abbas Motavalian4, Pardis Nematollahi5, Setareh Mohsenifar6 1- Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 2- Ministry of Health, Iran 3- Isfahan University of Medical Science 4- Iran University of Medical Science 5- Isfahan University of Medical Science 6- Unitted Nations Office on Drugs and Crime ,Tehran Background Injecting Drug Users (IDUs) are one of the most at risk groups for HIV and other blood born infectious disease. Tuberculosis (TB) is another infection which could be spread out from this group to the other part of the community through daily contacts. LTBI situation with or without HIV among IDUs is important for designing better harm reduction services in Iran for providing better services for both IDUs /DUs and community. Methods This is a cross-sectional survey with laboratory and/or radiologic tests , has been conducted in Tehran, Isfahan, Mashhad, Shiraz, Gorgan and Kermanshah in Iran in 2013. Cities has been selected by joint committee of United Nation Office on Drug and Crime in Iran (UNODC), Drug Control Head Quarter (DCHQ) and Center for Disease Control at Ministry of Health (CDC) as the supporters of the study .Participants were active (had injection in past month) and recent (had injection in past 6 months) IDUs receiving services from drop in centers recruited by convenient sampling. Results 420 IDUs (97.4% Male,2.6% Female) interviewed and checked for tuberculin skin test and HIV test and then based on selection criteria’s chest X-ray and sputum smear has been requested for 190 (45.2%)of them. HIV / PPD results are available for 99.3% and 94.8% of participants, respectively. HIV prevalence was 8.6% (0 to 18% in different cities; overall 9.1% of females, 8.6% males) and average positive tuberculin test was 35.7% (14.3% to 67.1% in different cities; overall 54.5% of females, 35.1% of males) of study participants. Odds ratio for positive tuberculin test calculated 3 (1.5<CI<6.4) in HIV positive IDUs comparing to HIV negative participants. PPD negative participants were younger than PPD positive (P value<0.04) but age difference for HIV positive VS negative participants were insignificant.All of the smear test were negative but radiologic findings were seen in 14.5% of patients with Chest X-ray. Conclusion Latent TB is very common among Iranian IDUs and the par- ticipants’ knoeledge and information regarding TB is very low ,therefore harm reduction programs should consider TB as one of the priorities in the current harm reduction services. Keywords Tubercolusis, HIV, Injecting Drug Users, Iran Social Work Services for Women and Children in Substance Abuse Treatment and Harm Reduction Leila Arshad Sun House Society, Tehran, Iran More than 20% of substance abusers are women. The growing increase of substance abuse (especially methamphetamine use) by women and decreasing the average age of first substance abuse among them is a major health issue affecting women and families. Most of Women Substance Abusers (WSAs) hesitate to seek treatment and supports because of the stigma around using a substance and limitations of providing services for them. Social workers can markedly improve treatment and support services for WSAs and their children. Social workers in substance abuse treatment and harm reduction settings focus on providing special services for WSAs in case of pregnancy, sexual abuse, sex-working, child care giving, domestic violence, poverty, homelessness, etc. Keywords Substance Abuse, Women, Child, Social Work Substance Use Disorders in Medically Ill Inpatients Atefeh Ghanbari Jolfaei, MD1 1- Mental Health Research Center, Iran University of Medical Sciences Substance use disordersare frequent in medically ill inpatients. The prevalence of substance use disorders in the general hospital inpatients ranges from 40% to 70% which is significantly higher than the rate of these disorders in general population. Although the frequency ofsubstance use problems within psychiatric consultation is up to 30%,substance use disorders often remain unrecognized in medically ill inpatients. It was reported that the rate of hospitalization increased among these patients and it was also shown that comorbidity of substance use disorders in medically ill inpatientsare associated with more complications and can influence the course and prognosis of underlying medical diseases. With regard to the complicationsof substance use disorders and their importantrole on the course of diseases andquality of life, diagnosis and management of substance use disorders are particularly important in inpatients of a general hospital. The aim of this paper is to describe the importance and methods of assessment and management of substance use disorders in inpatients of general hospitals. S148 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Early Onset Substance Use: Comorbid Psychiatric Disorders Elham Shirazi Child and adolescent psychiatrists, Mental Health Research Center, Tehran Institute of Psychiatry- Faculty of Behavioral Sciences and Mental Health, Iran University of Medical Sciences, Tehran, Iran Substance use disorder (SUD) in children is comorbid with ADHD and bipolar disorder in up to 80% of cases, with major depresive disorder in up to 50% of cases, and with anxiety disorders in up to 40% of cases. It is common in early onset schizophrenia, borderline personality disorder, history of physical and sexual abuse, learning disorder, language disorder, and oppositional defiant disorder (ODD). Comorbidity may precede, exacerbate, or follow the onset of SUD. Childhood psychopathology is associated with earlier onset of SUD in adolescence, more persistent course of SUD, and early return to it. Externalizing disorders are the most frequent comorbid disorders in early onset SUD and are more common in boys. Internalizing disorders are more common in girls with SUD. Comorbidity is more common in clinical population vs general population which is called Berkson’s bias. In clinical population of adolescents with SUD, 80% have cooccurring non-substance related mental disorder and more than 50% have at least 3 comorbidities. More than 80% have disruptive behavior disorders (DBD) including ADHD, conduct disorder (CD), and ODD. CD, ADHD, and mood disorders are the most common comorbid disorders, and more than 50% have mood and anxiety disorders. In general population of adolescents with SUD, 70% have comorbid psychiatric disorders. CD and ODD are the most common. Sixty percent have DBD, up to 32% have ODD, up to 32% have mood disorder, and up to 20% have anxiety disorders. Key words Adolescent, Comorbid Disorder, Substance Use Factors Influencing Transition to Methamphetamine among Youth Opioid Users in Tehran AlirezaNoroozi1, Mohsen Malekinejad2, Afarin Rahimi-Movaghar3, Minoo Mohraz4, Hossein Malekafzali5, William McFarland6, Kimberly Page7 1- Psychiatrist, Head of Substance Abuse Prevention and Treatment Office, Ministry of Health 2- Assistant Professor, Institute for Health Policy Studies, University of California San Francisco 3- Associate Professor of Psychiatry, Director of Iranian National Center for Addiction Studies (INCAS), Iranian Institute for Reduction of High-Risk Behaviors, Tehran University of Medical Sciences 4- Professor of Infectious Diseases, Iranian Research Center for HIV/AIDS (IRCHA), Iranian Institute for Reduction of High-Risk Behaviors, Tehran University of Medical Sciences 5- Professor, Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences 6- Associate professor of epidemiology, Public Health and Global Health Sciences, University of California San Francisco 7- Professor of epidemiology, Dept. of Epidemiology and Biostatistics, Division of Preventive Medicine and Public Health and Global Health Sciences, University of California San Francisco introduced to Iranian drug users. Twin epidemics of drug use and HIV infection emerged during late 1990s among people who inject drug particularly in prison settings. In response to that, a harm reduction policy adopted and scaled up across the country since 2002. During last 6 years the country encountered with an emerging epidemics of methamphetamine use. The epidemics spread rapidly parallel to domestic production of methamphetamine and currently it is the second most prevalent drug of use among people who use drug in the country. To explore factors influencing transition to methamphetamine we conducted a qualitative study on a diverse sample of 42 purposefully selected groups of youth noninjecting opioid users, injecting opioid users and stimulant users, as well as health care professionals in Tehran. The interviews were audio-recorded, transcribed and coded in Farsi using OpenCode 3.6 software, and then translated to English. We categorized perceived factors to approach or avert from methamphetamine use in 4 level including individual, drug specific, social/environmental and macro level/structural. Here we are going to present the perceived factors for transition to methamphetamine in details and discuss its implications for current national harm reduction program. Substance Use Disorders in Women in Iran Afarin Rahimi-Movaghar, MD, MPH* Associate Professor of Psychiatry, Iranian National Center for Addiction Studies (INCAS), Tehran University of Medical Sciences This is a review on substance use and substance use disorders in women in Iran. Substance use in women is considered a more hidden problem than men. Although in many countries, women consist of up to 40% of substance users, in Iran this rate is less than 10%. According to the 2011 national household mental health survey (IranMHS), 3.1% of women aged 15-64 had used an illicit drug or alcohol in the last 12 months, and 4 per 1000 met the criteria for a substance use disorder (SUD) in the same period. Although women start using substances years later than men, women with SUD have fewer resources (education, employment, income) than men and are more likely to live with those with SUD. They are more probable to suffer from a comorbid mood or anxiety disorder than men. In Iran, most women with substance use problems have children and are responsible for their care. HIV prevalence is around 10% and 1% in women who inject drugs and women with non-injecting drug use, respectively. Health service use for substance problem is very low among women with SUD. Women encounter significant barriers in accessing treatment, which consists of cultural, structural, financial and personal problems. Many women with SUD avoid mixed-gender treatment programs. More researches are needed to understand various aspects of initiation, patterns, consequences, and needs of women with substance use problems. Key words Women, Gender, Drug use, Addiction Opium has been the main drug of use in Iran drug scene for centuries. During last few decades heroin and injecting drug use Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S149 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Transition to Injecting Drug Use among Youth in Tehran, Iran; a Qualitative Study Afarin Rahimi-Movaghar, MD, MPH1*; Mohsen Malekinejad, MD, PhD2; Alireza Noroozi, MD3 1- Associate Professor of Psychiatry, Iranian National Center for Addiction Studies (INCAS), Tehran University of Medical Sciences 2- Assistant Professor, Institute for Health Policy Studies, University of California San Francisco, USA 3- Psychiatrist, Iranian National Center for Addiction Studies (INCAS), Tehran University of Medical Sciences Background and objectives Iran has a large population of opioid users that are potentially at risk of initiation of injecting. This study was carried out to investigate the factors facilitating transition from non-injection to injection drug use. Methods In this qualitative study, conducted in 2011, a total of 42 injecting and non-injecting drug users and health workers participated in the in-depth interviews. The interviews were audio-recorded and transcribed. OpenCode 3.6 software was used for analysis. Results The most frequently mentioned factor for transition from noninjecting drug use to injecting use was the high level of drug dependence. Injection decreased the cost of drugs several folds in short-term. Influence of others, either by learning from others, encouraged by them or feeling a force or pressure imposed by others, or similarities in the lifestyle of a non-injector with an injector also resulted in the transition. A desire to experience the immediate rush was rarely mentioned. Rather, the need to maintain function and reduce pain and suffering and overcoming financial difficulties, much far from the concept of pleasure-seeking behavior, were reported more frequently. The two main reasons to prevent drug users from initiation of injection were health concerns and control and pressure of the family. Conclusion After around a decade of adopting harm reduction policy and providing extensive treatment and HIV prevention services for drug users, Iran is facing a considerable extent of injecting drug use among youths, and it is necessary to plan for effective measures to prevent transition to injecting drug use and promote shifting back to non-injection. Keywords Route of Administration, Injecting Initiation, Risk Factors for Injecting, Protective Factors for Injecting, First Injection Episode. Factors Influencing Transition to Methamphetamine among Youth Opioid Users in Tehran Alireza Noroozi1, Mohsen Malekinejad2, Afarin Rahimi-Movaghar3, Minoo Mohraz4 1- Psychiatrist, Head of Substance Abuse Prevention and Treatment Office, Ministry of Health 2- Assistant Professor, Institute for Health Policy Studies, University of California San Francisco 3- Associate professor of psychiatry, Director of Iranian National Center for Addiction Studies (INCAS), Iranian Institute for Reduction of High-Risk Behaviors, Tehran University of Medical Sciences 4- Professor of infectious diseases, Iranian Research Center for HIV/AIDS (IRCHA), Iranian Institute for Reduction of High-Risk Behaviors, Tehran University of Medical Sciences Opium has been the main drug of use in Iran drug scene for centuries. During last few decades heroin and injecting drug use introduced to Iranian drug users. Twin epidemics of drug use and HIV infection emerged during late 1990s among people who inject drug particularly in prison settings. In response to that, a harm reduction policy adopted and scaled up across the country since 2002. During last 6 years the country encountered with an emerging epidemics of methamphetamine use. The epidemics spread rapidly parallel to domestic production of methamphetamine and currently it is the second most prevalent drug of use among people who use drug in the country. To explore factors influencing transition to methamphetamine we conducted a qualitative study on a diverse sample of 42 purposefully selected groups of youth non-injecting opioid users, injecting opioid users and stimulant users, as well as health care professionals in Tehran. The interviews were audio-recorded, transcribed and coded in Farsi using OpenCode 3.6 software, and then translated to English. We categorized perceived factors to approach or avert from methamphetamine use in 4 level including individual, drug specific, social/ environmental and macro level/structural. Here we are going to present the perceived factors for transition to methamphetamine in details and discuss its implications for current national harm reduction program. S150 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S151 P EO R T S POSTER The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Condition of Management of Prevention and Treatment Program of Drug Abuse in the Network System of Ahvaz University of Medical Sciences: 1392 Zohreh Abbasi1, Abbasi Z(MA)2, Davasaz Irani R(MPH)3, Barzkar A(MA)4, Mansouri S(BA)5 1. Department of Mental, Social Health and Addiction .Health Center of Khuzestan Province, Ahvaz Jundishapour University of Medical Science 2. General Psychology 3. Department of Mental, Social Health and Addiction .Health Center of Khuzestan Province, Ahvaz Jundishapour University of Medical Science 4. Clinical Psychology_Manager of DIC 5. General Psychology-Center of Local Mental Health Avaye Zendegi - Ahvaz Background and Aim Improving the nation’s health care system is possible only when all the sub-systems and components subsidiary are possessed of a dynamic management. This study aimed to evaluate management of prevention and treatment program of drug abuse in the network system of Ahvaz University of medical sciences Methods This was an applied study that conducted in descriptive- analytic method. The study sample consisted of all managers at various level of management of prevention and treatment program of drug abuse in the network system of Ahvaz University of medical sciences (n = 115) that were selected by census method. Data was gathered by a researcher- made questionnaire that its validity was cheked by expert opinion. This questionnaire included four subscales: programming, organizing, functioning and control that was graded on a five-point Likert scale from very low to very high. The data were analyzed using descriptive statistical methods by SPSS16 software. Results The Results showed that overall ,condition of management of prevention and treatment program of drug abuse in the network system of Ahvaz is moderate. In fact performances of managers in all aspects of management were moderate. In comparing Results, the best performance belonged to monitoring and control,then planning. Executive functions and organization were ranked respectively the third and the fourth. Conclusion Due to the moderate majority of managers in management of prevention and treatment program of drug abuse, this program is in need of reform in order to provide basic services to the field of substance abuse prevention and treatment with better quality in Ahvaz University of Medical Sciences. Keywords Drug Abuse Program, Management, Network System Investigate the Role of Additional Behaviours and Impulsivity in Forecasting the Reactions of Bipolar Patients Moslem Abbasi1 1. Department of Psychology, Faculty of Literature and Human Sciences, Salman Farsi University of Kazerun, Kazerun, Iran Background and Aim Introduction:The aim of this study is to investigate the role of additional behaviours and Impulsivity in forecasting the reactions of bipolar patients. Methods The design of this investigation is descriptive- cross sectional. It is also a correlation design. The statistical society of this investigation is all outpatients and combined to bed patients who are affected to this disorder, in Isar and Fatemi hospital of Ardabil from Shahrivar to Esfand 1390 (Sep- March of 2011-2012). The statistical sample of this investigation include 60 individual of bipolar patients. (30 of them are affected to typ 1 and 30 of them are affected to typ 2 bipolar disorder). They were selected among patients who were combined to bed or out patients of Isar and Fatemi hospital of Ardabil in coincidently. Togather the needed information it was used of questionnaire. To resolve the data of this investigation, it were used of Pearson,s correlation coefficient and multi variable regression analysis and multi variance analysis test.(MANOVA). Results The result of the investigation showed that there is negative relation between additional behaviours and the reaction of the patients and a possitive reactionability between Impulsivity (& them dimansions) and additional behaviours. (P≤ 0.01). Conclusion Also the Results showd that there is meaningful relation between bipolar patients from the respect of additional behaviours and their reactionability and Impulsivity. Keywords Additional Behavior, Impulsivity, Reactionability& Bipolar Patients. Compare Alexithymia, Self-Injury Behavior and Emotional Processing in Single Substance Drug Addicts and Normal Controls Moslem Abbasi1, Z. Pirani, P.h.D2, A.R. Mehrabi MSc3 1. Department of Psychology, Faculty of Literature and Human sciences, Salman Farsi University of Kazerun, Kazerun, Iran 2. Department of Psychology, Faculty of Literature and Human sciences, University of Islamic Azad University of Arak. 3. Department of Psychology, University of Islamic Azad University of Khorasan Razavi,Neyshabur, Science and Research Branch Khorasan Razavi,Neyshabur. Background and Aim The purpose of this study is to compare Alexithymia, Self-Injury behavior and emotional processing in single substance drug addicts and normal controls. Methods The study of 1200 addicts individual in Arak drug addiction treatment centers formed in 1393 that passed the stage of detoxifi- S154 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall cation. The sample consisted of 120 addicts single-substance drug addiction treatment centers in Arak in 1393 who were selected by using convenience sampling from among those detox. Data were collected using the Toronto Alexithymia Scale, emotional processing scale, self-injurious behavior and addiction severity index. Data were analyzed using t-test. Results The Results indicated that there is significant discrepancy between single-agent drug addicts and normal subjects in terms of Alexey Time, Khvdasyby behavior and emotional processing. Conclusion In total, the inability to express emotions, self-injury behaviors and difficulties in emotion regulation difficulties women addicted to drugs. Therefore, these variables can be used in the interpersonal behaviors of drug users, is affecting society. Keywords Alexithymia, Self-Injury Behavior ,Emotional Processing, Substance Drug Addicts A Qualitative Study on Stereotypical Beliefs and Experiment of Addicts About the Influence of Taking Drugs on Sexual Life and Family (Case Study of Addicts in Arak City) Ebrahim Abbasi1, Mahmood Abbasi2, Ahmad Abbasi3, Sepideh Kamyani4 1. Expert at DCHQ 2. Expert at Legal Medicine Organization 3. Expert at Markazi Government, Arak, Iran 4. Reporter Background and Aim A qualitative study on Stereotypical beliefs and experiment of addicts about the influence of taking drugs on sexual life and family Research method: the population includes addicts who are taking a especial drug that are chosen by available sampling method. According to the research that is done qualitative, data gathered by empathic observation and interview method. The method of analyzing data is by analyzing content. Methods the population includes addicts who are taking a especial drug that are chosen by available sampling method. According to the research that is done qualitative, data gathered by empathic observation and interview method. The method of analyzing data is by analyzing content Results Conclusion It is appear that the lost item in the prevention of addiction is not paying attention to the positive influence at the beginning of taking drugs. In other words performing the risky preventive programs not only cannot prevent from taking drug, but acting as an anti advertisement. It should be noticed that by reducing the sexual function, it affects the relation with the spouse and leads to other problems (such as divorce, emotional divorce, illegal sexual relation, violence, disputations, etc). Also most of addicts believe to their friends about the positive influence of drugs rather than governmental organizations, so that Stereotypical beliefs as a strong effect on addiction Keywords Stereotypical Beliefs, Addiction, Experiment of Addicts. Comparing Sexual Dysfunction in Addicted Women Before and After Addiction Treatment Ebrahim Abbasi1, Ahmad Abbasi2, Mahmood Abbasi3, Sepideh Kamyani4, Narges Akbary5, Hamid Reza Shamsi6 1. Expert at DCHQ 2. Expert at Markazi Government, Arak, Iran 3. Expert at Legal Medicine Organization 4. Reporter 5. Expert at DCHQ 6. Expert Addiction Background and Aim In this research we compare sexual disorder in addicted women before and after addiction treatment. Methods This is a quasi-experimental study.duo to research factor, we choose 70 addicted women who were in their treatment period (medically or not medically). We choose those who passed at least one month of treatment and their sexual function analyses before and after treatment. For taking information we use demographic questionnaire and made questionnaire (which its validity is approved) and sexual satisfaction questionnaire. For analyzing the data we use descriptive statistics and tests. Results The level of sexual desire and sexual satisfaction in the period of taking drugs and in the period of maintenance treatment has a big difference. In other words treated people have more strengthful sexual desire and more qualified intercourse. Also by treating the addicted woman and therefore improving sexual function, family issues (like violence, disputations, illegal sexual relations and…) will reduce. Conclusion Most of addicts express the strengthening of sexual desire as the reason for taking drugs, after a while of taking drugs, the relish of taking it will be double, however after a period, the sexual desire will reduce and therefore it leads to violence and disputation in the family. Most of addicts get the positive influence of drugs from their friends which are differing from what they experience Addicted women that are treated have less sexual dysfunction comparing to the time that they taking drugs. More important, because of improving sexual function, the illegal sexual relation will increase, that indirectly can lead to family disputations and violence. This issue should be noticed by the experts and therapists to have addiction treatment side by side sexual dysfunctions in women Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S155 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Keywords Sexual Disorder, Drug Abuse, Addiction Treatment The Effect of Comprehensive Psychological Interventions on Decrease the Tendency to the Use of Substance in Drug Removed Hossein Abbasi Molid1, Shahram Sheikhani2, Mohhammad Reza Miri 3, Sarif Barati4 1. Research Institute of Police Sciences and Social Studies (naja) 2. MA of Clinical Psychology , Preventive Assistant Welfare South Khorasan 3. Associate Professor of Medical Sciences University of Birjand 4. Professor of Allameh Tabatabai University Background and Aim Introduction and purpose: In this research, the researchers studied the efficacy of comprehensive psychological interventions on decrease the tendency to the use of substance in drug removed in Birjand city, Iran. The population consisted of all men who were under antitoxic treatment, at least for one year. The number of qualified people for the research was 2100 from among which 80 people were chosen with available sampling and then they were divided randomly into two 40- people groups (test and control groups). Methods Tool and Method: A researcher- developed questionnaire was used to measure the amount of tendency to the Use of substance in selected sample. Then, integrative comprehensive psychological interventions including family- therapy (8 session), couple- therapy (8 session), group- therapy (8 session) and Self -help groups (8 session) were conducted on test- group members based on a compiled didactic- psychic package during 3 months. There were no interventions for control group. When the interventional programs were completed, two groups were examined with the post- test and the Results were analyzed statistically. To analyze the data, descriptive approaches and also multi- variable quariance analysis test and t-test were used. Results The Results show that there is a meaningful difference between the difference of the average of pretest- posttest scores in test group and control group. The Results of quariance analysis with F= 28.25 indicates that there is a meaningful difference between two groups (P≤ 0.001). Conclusion The Results of this research show that the comprehensive psychological interventions decrease the tendency to the use of substance in drug removed, meaningfully. The findings of this research are compared to the findings of previous researches and discussed. Keywords Addiction Survey of Women Involved with the City of Kerman Reza Abbasiraeni1, Samira Ashrafganjooi 2, Reza Abbasiraeni 3 1. Welfare Directorate General of Kerman Province. 2. Ashrafganjooi 3. Abbasiraeni Background and Aim Drug dependency and it is one of the most important social issues in the world. However, over the past few years more or less in some women who use drugs, but addiction is generally considered to be an issue for men, But in recent years, along with the changing social roles of women, raising the possibility that the material has increased, Global and regional changes in food consumption patterns to extend the field of drug abuse among women is provided Objective: This study examined the experience of women involved in drug addiction and drug-dependent women living in the city of Kerman. The main research questions: 1- the addiction of drug-dependent women 2 - due back to addiction after quitting the drug-dependent women, 3 - emotional experience drug-dependent women consume 4 - emotional experience of non-drug-dependent women consumption 5 - feels towards drugdependent women66 - determine the type of social relationships, drug-dependent women from their own perspective. Methods Method, which has been accompanied by a qualitative research approach. In order to understand the experience of addiction from an interpretative phenomenological approach was used. Interview and observation method of data collection techniques and data analysis methods were colaizzi. Haas R snowball sampling method selected. Number of study subjects was 30people., That most of them were in the age group of 21-25 years Results The main drug respondents crack. The main causes of addiction tends to respondents are: family history of addiction, mental health problems, a feeling of frustration, poor family relationships, family torn apart, the social environment, with friends, individual factors, the medical aspects of addiction They have been effective The social disorganization theory, social bonding, stigma woman, and economic deprivation can be explained. Respondents returned the leading cause of addiction, social stigma, coercion theory of social stigma and negative evaluations of the identity of a woman can be explained and individual factors can not be explained in sociological theories of earlier Conclusion In this study it was observed that the objectives focus on sociological theories do not exist and can not be explained. The Results for the basic concepts of extension Mvdjvd theory is applicable. Keywords Addiction, Women Comprehensive Psychological Interventions, Decrease the Tendency to the Use of Substance, Drug Removed. S156 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Addiction and Divorce (With Emphasis on Article 1130 of the Civil Code) Shahrzad Abbaslou1 1. MS ShahrzadAbbaslou - Graduater Student of Law - Shahid Bahonar University of Kerman, Kerman, Iran. used in this study include self-esteem and self -efficacy. The design of the study was pre-test/post-test with a control group. After random selection of experimental and control groups, the pre-test was conducted on two groups, then the experimental intervention was performed and after completing the training program, the post-test was administered to both groups. Results Background and Aim Today, in addition to the many problems of addiction is a phenomenon that has to be considered as one of the causes of divorce. Divorce is actually a way to end the failed marriage. Marriage in Islam is respected. Divorce, legal way to end this sacred bond in this study, According to the Article 1130 of the Civil Code the role of addiction in to the realization or non-realization of divorce, Was evaluated. The Results show that emotional intelligence training enhancing of self-esteem and self -efficacy the experimental group compared to the control group. Conclusion The Results indicated that the emotional intelligence training can enhancing of addicted women’s self- esteem and self -efficacy Keywords Methods The Civil Code investigated in this study, the addiction was considered as one of the causes of divorce.This study describes and analyzes the role of addiction in divorce . acording to the article 1130 of Results The Results of this study indicate, if the drug caused life continues to be difficult, it can be considered as one of the causes of divorce and Finally, the court examined the circumstances and conditions governing the issue of the divorce decree to prove hardship. Emotional Intelligence, Addicted Women, Self-Esteemm, Self -Efficacy The Impact of Spiritual Intelligence on the Happiness of Addicted Men Attended Shahid Famili Clinic in East of Tehran Zahra Abdikhan1, Masomeh Sahabikia2 1. M.S.c Azad Univercity 2. M.S.c Azad Univercity Conclusion In general, the hardness of wife’s life gives her the right to divorce if she can prove it According to the second paragraph of Article 1130 of the Civil Code amendments: wife can divorce if living with addicted man be so hard and Intolerable Keywords Addiction, Divorce, Hardship, Marriage, Proof of Extreme Hardship The Effectiveness of Emotional Intelligence Training on Enhancing of Addicted Women’s Self-Esteem and Self -Efficacy Elham Abde Pour Sabzghabaei1 1. Islamic Azad University, Sciences and Research Branch, Ellam Background and Aim The purpose of this study was to examine the effectiveness of emotional intelligence training on enhancing of addicted women’s self-esteem and self -efficacy Methods The population consisted of all addicts’ women who were referred to Ahvaz self-report centers. The sample included 24 who were selected by simple random sampling method and were assigned to two experimental and control groups. The instruments Background and Aim The present investigation, which was a practical research and a descriptive-survey one in terms of method of collecting data, was aimed to study the impact of spiritual intelligence on the happiness of addicted men attended Shahid Famili clinic in east of Tehran Methods Using random sampling method, 180 individuals were chosen as a sample size and answered to the questionnaires of King’s standard spiritual intelligence (2008) and Oxford’s happiness (1989). The data analysis was carried out using Structural Equation Modeling (SEM) and Smart PLS 2.0 software in two parts of measurement and structural. Results Technical features of the questionnaire were checked in the measurement model and required reforms were carried out. Moreover, the structural coefficients of the model were used in order to check the research hypothesis in the structural section Conclusion The Results demonstrated that spiritual intelligence and its dimensions have positive and significant impact on individuals’ happiness. Keywords Spiritual Intelligence, Critical Thought of Being, Creation of Personal Meaning, Transcendental Consciousness, Development of Consciousness State, Happiness Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S157 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Personality Disorders and Substance Abuse in Kermanshah Central Penitentiary Convicts Jalal shakri1, Nasrin Abdoli2,Vahid farina3 1. Psychiatrist and Associate Medical Sciences, Kermanshah 2. PhD Student at University of Mashhad Imam Reza 3. Psychiatrist and Associate Medical Sciences, Kermanshah Background and Aim prevent mental disorders and substance abuse and its related crime happen has attracted psychologists and lawyers. Year of mental illness or neurosis or behavior that is not an essential part. Psychological distress in patients with dementia in a person’s health can arise. Psychologists believe that concerns one of the most important signs of neurosis and is the most common type. The temporary type is concerned, both continuous.are. Methods The questionnaire consisted of 71 questions that diagnostic software in their effortless for individuals diploma education was incomplete and over diploma has been used. Rating scales and questionnaires three and nine clinical scales. And analysis was performed using spss software. Results The method of sampling for the men sentenced to penitentiary center in Kermanshah be convicted of women due to the limitations of prison rules were excluded from the age of the lowest and most age groups, respectively, 18 to 60 years maximum percentage of convicts between the ages of 26 toAnd a history of drug abuse, 46 percent were reported., And most consumables and drugs, opium and heroin, crack glass ... And 68 per cent of the consumer experience all the ingredients were., And the employment percentage of 71% of self-employed and unemployed, respectively., And disorders common to 56% of personality disorder and 18.5 percent of mental disorders.11.5 percent disorders psychotic and 21.5 had a personality disorder and neurosis together. between in communication disorders, neurosis and substance abuse (p = .019). Significant relationship exists. Conclusion This study shows an association between substance abuse, neurosis as anxiety and depression have underlying personality disorder, and diagnosis and treatment of these disorders to abuse Prevention Materials and social harms family Compensation psychological and economic to the individual and to society. Keywords Substance Abuse Disorders, Neurosis, Psychosis, Personality Disorders. Effect of Training on Stress Management Techniques to Reduce Anxiety and Depresion in People with Drug-Dependent Sara Abdolvahaby1, Malihe Pashib2, Zahra Hematy Javanmard3 1. MA in Clinical Psychology, Islamic Azad University of Birjand 2. Master of Clinical Psychology Torbat Heydariyeh University of Medical Sciences , Torbat Heydariyeh,Iran 3. MA in Clinical Psychology, Islamic Azad University of Birjand Background and Aim The main objective of this study is to investigate the effect of training in stress management techniques to reduce anxiety in people with drug-dependent Methods The tool used in this study is Beck’s Anxiety Inventory. The independent variable of the present study is 8 session treatment to deal with stress performed as a group for the experiment group and the dependent variable which is the score each subject is acquired in Beck’s Anxiety Inventory. The statistical community of this study ismale drug addicts living in Mashhad. Subjects were selected randomly and then classified at random into two groups of 15 people of experiment and control groups. In this study, semi-experimental research method and pretest-posttest design with control group was used and data have been analyzed through SPSS software and T tes Results The Results of the study showed that stress treatment has been effective in reducing depression of drug users. Therefore, the training program of how to deal with stress plays a main role in reducing drug-addicted users decided to quit and thus help them quit more successful in a longer period of time. Conclusion The Results of the study showed that stress treatment has been effective in reducing depression of drug users. Therefore, the training program of how to deal with stress plays a main role in reducing drug-addicted users decided to quit and thus help them quit more successful in a longer period of time. Keywords Training to Deal with Stress,), Drug-Dependent Individuals Analyzing the Effectiveness of Lazarus Multimodal Therapy on Craving and Health Promotion of Drug Abuse Maryam Abedi1, Roghayeh purshahbaz2, Marziyeh sattari3 1. Science and Research Branch Islamic Azad University,Arak 2. Science and Research Branch Islamic Azad University,Arak 3. Payam Noor University, Azarshahr Background and Aim Addiction is a complex disease which is identified with features such as compulsive behaviors, irresistible temptations, constant search for drug and its consumption, even in situations with negative consequences. Therefore, in order to treat addiction it is essential to use psychotherapy techniques beside detoxification. The main objective of this study is to provide a method based on cognitive - behavioral techniques which is entitled Lazarus Multimodal Therapy to be used in hospitals. Methods The present research is a kind of Quasi-experimental research S158 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall with pre-test, post-test and control group. The research population of the present study includes all patients with drug abuse in Azarshahr. Among those people who were volunteers to participate in the study, after reviewing some criteria (the duration of drug use at least for 6 months, at least one or more previous unsuccessful treatment, no severe mental illness), 40 people were selected and then they were randomly and equally replaced in experimental and control groups. To collect data, General Health Questionnaire GHQ and Tiffany Craving Questionnaire were used. Lazarus Multimodal treatment was performed in 12 sessions of 90 minutes during 3 months in the experimental group, and craving and general health was measured before and after the treatment. Results The Results of MANCOVA test showed that Lazarus multimodal therapy significantly decreased depression (P=.0005), anxiety (P=.0005), and social dysfunction scores (P=.0005), but it did not have a significant effect on physical symptoms subscale (P=.308), and the reduction of craving (craving (P = .001)) was observed in individuals. .53 Severity of addiction was less in resilience addicts. Conclusion Severity of addiction was less in resilience addicts. These findings could be an explanation for regression addiction. Due to the low resiliency , addicts taken down regress quickly and lose their normal functions in a quick break away from the family and society. Resiliency skills can be acquired with teaching .the social harm that caused by addiction can reduced with teaching Resiliency skills. These findings to help contribute to the better understanding of addiction, Prevention of addiction and social damage, can also help to the Professionals to provide the best specific treatments in this field Keywords Resiliency, Severity of Addiction The Comparison of the Addiction Potential in Resilience Soldiers and Unresilience Soldiers Conclusion It can be claimed that Lazarus Multimodal Therapy was effective in the general health promotion of people with drug abuse, and it reduced craving in individuals. Somayeh Abedi1 1. Payame Noor University of Shahrood Background and Aim The aim of this study was to The Comparison of the Addiction Potential in resilience Soldiers and unresilience Soldiers. Keywords Multimodal Therapy ,Health Promotion , Drug Abuse Investigate The Relationship between Resiliency and Severity of Addiction in Methadone Treatment Addicts Somayeh Abedi1, Ahmad Borjali2, Ezatollah Kordmirza3 1. Allameh Tabatabai University-Tehran Iran 2. Professor of Allameh Tabatabai University 3. Assistant Professor of Alborz University Methods 50 soldiers were selected from the shahrood garrison, their rate of graduates were high school .they were selected through random sampling. Then Resiliency Scale Connor and Davidson (2003) (CD-RISC) Addiction Potential Scale (APS) was performed. Results T-test was significant (t = 1.98). The Results showed Addiction Potential is significantly higher in unresilience Soldiers. Background and Aim Addiction is one of society’s problems that, has weakened the foundation and institutions of human society in recent years. And the capital cost for the fight, treatment, and it, s damages are spent. The aim of this study was to investigate the relationship between relationship between resilience and severity of addiction in methadone treatment addicts. Methods So, 56 addict that was in treatment with methadone that are range 18-30 years old and they had diploma ,Associates And BA Degree selected with used simple random sampling. They are responded to Resiliency Scale Connor and Davidson (2003) (CD-RISC) and severity of addiction Semi-structured interviews Mac lellan and co-workers (ASI) (2006) was performed. Conclusion Addiction Potential in un resilience Soldiers was greater than resilience soldiers. Resiliency skills can be acquired with teaching. incidence of addiction among soldiers can reduce with Resiliency training Keywords Addiction Potential, Resiliency The Relationship between Irrational Beliefs and Resiliency in Methadone Treatment Addicts Somayeh Abedi1, Ahmad Borjali2, Ezatollah Kordmirza3 1. Allameh Tabatabai University-Tehran Iran 2. Professor of Allameh Tabatabai University 3. Assistant Professor of Alborz University Results The Results showed negative and significant relationship between resiliency and severity of addiction. The correlation was 0 Background and Aim Nowadays , we can better recognize addiction and its outcomes Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S159 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall and can improve Appropriate encounter. The aim of this study was the relationship between irrational beliefs and resiliency in methadone treatment addicts. Methods So, 56 addicts that was in treatment with methadone that are range 18-30 years old and they had diploma ,Associates And BA Degree. They were selected with using Simple random sampling method. They answer to Jones irrational beliefs scale(1968)(IBT), Conner and Davidson resiliency scale(2003)(CD-RISC) . Results The Results showed negative and significant relationship between irrational beliefs and resiliency . The correlation was 0 .37 Conclusion Irrational beliefs was less in resilience addicts. This finding suggests that to increase resiliency and prevention of social harms and treatment of addiction, irrational beliefs must be modified Keywords Resiliency, Irrational Beliefs Study of the Relationship between Personality Traits of Addict and Non-addict Youths of Esfahan Zahra Adham1, Azam Shamohammadi 2 1. M.A. in General Psychology,Department of Justice Crime Prevention Isfahan 2. M.A. in General Psychology, Esfahan Public Education Background and Aim The main aim of the present research is to investigate the relationship between personality traits including: neuroticism, extroversion, agreeableness, openness and conscientiousness on selfreferred substance abusers and the normal group. Methods This is a discriptive research in which the relationship between 30 addicted persons who referred to treatment centers and 30 normal persons is investigated. In order to collect data, NEO inventory (revised abridged form) was utilized. The collected data were analyzed by correlation coefficient. Results There is a significant relation between the addicted group and the normal one in most personality disorder indices (p< 0.05). The addicts acquired different scores in comparison with the normal group in all five dimensions, acquired higher scores in neuroticism dimension, and obtained lower scores in all other dimensions. Conclusion Results of this research revealed that the scores of addicted people in personality factors continum generally tends to the negative side (for instance, high neuroticism and low openness, agreeableness and conscientiousness). And it can be finally asserted that unhealthy personality traits are seen more in these people. Keywords Personality Traits, Youth, Addict. Drug Abuse Pattern and Frequency of High Risk Behaviors the Cliens to Outpatient Addiction Treatment Centers Abolhassan Afkar1 1. PhD Management of Health and Cure Services, Social Determinants of Health Research Center (SDHRC), Guilan University of Medical Sciences, Rasht, Iran Background and Aim Today, the issue of addiction to narcotics or drug abuse has evolved into a global and universal problem. This study was performed with the goal of determining of the drug abuse pattern and high risk behaviors among the clients to DIC of Private sector of Rasht. Methods This is a cross-sectional study in 2013.The questionnaire contained 10 general questions about demographic characteristics and 30 specific questions about drug abuse and high-risk behaviors. This questionnaire was completed via interviewing the addicts. The reliability of the questionnaire was checked using Cronbach’s alpha (α=0.86). SPSS software was used to analyze the Results and, descriptive statistics such as frequency tables and inferential statistics including the chi-square test were used. Results The average age of patients was 38.8. Opium and crack were the most widely used narcotic among subjects, respectively before referring to DIC centers. In addition, 9.8% of them had a history of using injectable drugs, among which 20.6% had used shared needle for injection. 80.9% had experienced sexual intercourse, among which 48.4% were unmarried. There was a significant statistical relationship between men and women (p=0.001). There was a significant statistical relationship between running away from home and the consumption of narcotics (p=0.002). Results also indicated that committing suicide had a positive significant relationship with the variations of age (p=0.001), the age of smoking onset (p=0.002) and method of use (p=0.003). Conclusion This study knows the following items as the main high-risk behaviors of addicts: taking narcotics by injection, using common syringe and needle, blood playing background, imprisonment background, making homosexual intercourses, suicide, and using no condom during sexual intercourse. Keywords Drug abuse, High Risk Behaviors, Addiction Treatment Some of Characteristics of Women Referred to Drug Addiction Treatment Centers in Kermanshah Touraj Ahmadi-Jouybari1, Masoud Moradi2, Farid Najafi3, Vahid Farnia4, Abbas Aghaei5 S160 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall 1. Internist, Substance Abuse Prevention Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran 2. MSc of Psycology, Substance Abuse Prevention Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran 3. PhD of Epidemiology, Substance Abuse Prevention Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran. 4. Psychiatrist, Substance Abuse Prevention Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran. 5. PhD student in Epidemiology, Substance Abuse Prevention Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran. Background and Aim The prevalence of substance abuse in women’s society, have been rising in recent years. Therefore, this study whit aim to assessing some characteristics of women admitted to addiction treatment centers in Kermanshah province was conducted. Methods This is a cross-sectional (descriptive - analytical), in which all women attending drug treatment centers in Kermanshah province in 2102 were enrolled. According researcher check list, list of the required information was obtained from medical records and, if necessary to extra information or the patient’s files were incomplete, with treating physician or expert individuals in the center getting connected. Results Number of 72 women referred to health centers treated with conservative therapy were studied, mean age was 38.33 (11.88 ±). 50 patients (70%) referred to center of the city of Kermanshah and 22 patient referred to treatment centers in other city of province. Average age at first abuse was 27.2 (4.8 ±) and opium (75%) was the must consumed in first abuse. 54 of these patients had a family history of addiction and 33 (61%) of whom have husband whit substance abuse. The age of onset of smoking and age of first drug abuse correlated significantly (p <0.001). 6 (8%) patients had a history of injection and 3 of them (100% of participants attempted suicide), have a history of suicide attempts. Conclusion Less than thirty years of age have the highest risk of addiction and family history (especially addicted husband) is one of the major risk factors for drug abuse is a tendency to substance abuse in women. So along with treatment and patronage of men with addiction at the community, supporting to their families is very necessary and important. Keywords Addiction, Women, Substance Abuse Epidemiology of Substance Abuse and Dependence in Patient Referred to Substance Abuse Treatment Centers in Kermanshah Province, Year of 2012 Masoud Moradi1, Touraj Ahmadi-Jouybari2, Farid Najafi3, Vahid Farnia4, Abbas Aghaei5 1. MSc of Psycology, Substance Abuse Prevention Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran. 2. Internist, Substance Abuse Prevention Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran. 3. PhD of Epidemiology, Substance Abuse Prevention Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran. 4. Psychiatrist, Substance Abuse Prevention Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran. 5. PhD student in Epidemiology, Substance Abuse Prevention Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran. Background and Aim Substance abuse is one of the most comlex problems in all of the contries. This study aimed to specifying the substance abuse and dependence in patient referred to substance abuse treatment centers in Kermanshah province in year of 2012 . Methods This cross-sectional study carried out among patients referred to substance abuse treatment centers in Kermanshah province in 2012. Necessary information collected by trained colleagues. Patients files in all of the treatments centers (80 center in 2012) was assessed. And if necessary to extra information or the patients files was incomplete, with treating physician or expert individuals in the center getting connected. For analysis SPSS version 16 was used. Results Overall, 2562 patients, information on substance abuse treatment centers in 2012 were collected. The mean age of subjects was 37.98 (± 11.18) years. More than 97 percent were males. Opiates, tramadol and cannabis respectively have highest proportion among the materials that consumed in first time by the subjects. Average years of traditional substance abuse was much higher than this average among industrial materials. Proportion of substance abuse did not differ significantly between men and women, while this proportion about non-narcotic and synthetic materials were significantly different. Conclusion Considering the The Results of this study can be said that substance abuse is a problem that has plagued our community, and the size, cost and burden of that is increasing. And Synthetic drug abuse is on the rise too. For the treatment and prevention of access to these new materials, new ways of treating of these materials should be searched. Keywords Drug Abuse, Drug Addiction, Drugs, Synthetic Substance The Effectiveness of Self- Management Skills Training on Junior High School Students’ Self-Esteem to Drug Abuse Prevention Parvaneh Aghajari1, Sousan Valizadeh2, Mohammad Hashtrudizadeh3 1. Department of Pediatric Nursing, Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran 2. Department of Pediatric Nursing, Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran 3. Medical Sciences Faculty, Maragheh, Iran Background and Aim One of the healthy people objectives to 2020 is the health edu- Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S161 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall cation programs in schools to prevent health problems such as violence, suicide, and drug abuse. Life skills training (LST), according Bandura’s Learning Theory, are offered to this aim and communication skills is an integral part of LST. This study was performed to determining the effectiveness of self-management skills training on junior high school students’ self-esteem to drug abuse prevention. Methods This study is a pre and post test quasi- experimental study with control group that 417 students participated in 2 and 3 grades of Maragheh’s middle schools. Eight girls’ and boys’ schools were selected randomly through the schools list of Education office and after pre-test, were divided in 2 groups. In the case group, we performed the LST program in the 8 session, and then tested both of the case and control groups. The questionary included the demographic questions PSC, CPSC, and HSS scales. Data were analyzed by SPSS/15 and t-test, and χ2. Results After intervention, differences between post test’s and pre test’s mean and standard deviation of self-esteem and problem solving skills in intervention group were significantly increased (P=0.02, P<0.001) but in case group they were decreased. There are not any difference between gender and grade with decision making and problem solving skills, self-control, and self-esteem. Conclusion In the case group self-management skills training had positive effect on self esteem, and then it is recommended to be used in school as a protective factor for drug abuse. Keywords Students, Problem Solving, Decision Making, Self Concept, Prevention & Control Study of Abandon and Tendency to Addiction in Addicts who Referred to Health Setting in Urmia Nader Aghakhani1,Nader Aghakhani2, Ali Eftekhari3, Abbas Zarei4, Narges Rahbar5 1. Urmia University of Medical Sciences, Urmia, Iran 2. Urmia University of Medical Sciences, Urmia, Iran 3. Legal Medicine Research Center in Urmia, Iran. 4. Legal Medicine Research Center in Urmia, Iran. 5. Faculty of Nursing of Urmia University of Medical Sciences, Nazloo Road, Urmia, Iran Background and Aim Addiction is a widespread phenomenon that requires a comprehensive vision that specialists and researchers should be involved. There isnot a detailed study about the factors at the onset of addiction based on cultural and economic in Urmia, Iran, the study about this title was performed to determine abandon and tendency to addiction in addicts who referred to health setting in Urmia. Methods In this descriptive and analytical study, 400 addicts who referred to the forensic drug abuse abandon center based on the multistage cluster sampling in Urmia city were studied by a questionnaire that its content validity confirmed by experts and the members of the scientific board and reliability was confirmed by test of internal index. Results It was clear that encouragement of friends and spending time with friends and their tendency that didnot not allow to leave the drugs were the most important cause to determine abandon and tendency to addiction in addicted men who referred to health setting in Urmia. There was a significant relationship between their tendency with level of literacy and cigarette smoking in their father ((p>0.05). Conclusion According to the findings, determining rules about awarment, decreasing the tendency to addiction in addicts and establishment of consulting centers can useful to reduce the problems Keywords Abandon, Tendency, Addicts, Urmia Study of Psychological Dimensions of Addicts who Referred to Health Settings in Urmia, Iran Nader Aghakhani1, Dr. Nader Aghakhani2, Dr. Ali Eftekhari3, Dr.Abbas Zarei4, Narges Rahbar5 1. Urmia University of Medical Sciences, Urmia, Iran 2. Urmia University of Medical Sciences, Urmia, Iran 3. Legal Medicine Research Center in Urmia, Iran. 4. Legal Medicine Research Center in Urmia, Iran. 5. Faculty of Nursing of Urmia University of Medical Sciences, Nazloo Road, Urmia, Iran Background and Aim Addiction is a chronic and reversible disorder with deep social, psychological and physiologic and economic impression on human being. This problem is one of the most important, widespread concern and a preventable risk to health. So far, no efforts in the field of accurately study about the psychological aspects of psychological profile in addicts in Iran, in general and specifically ﻩ n Urmia has not been carried out. This study determined psychological dimensions of addicts who referred to health settings in Urmia to shoe the present condition of them. Methods The survey included demographic information of 400 addict who were selected based on the multistage cluster sampling. Data were collected by using SCL-90 – R .All data were analyzed by SPSS16 software and presented with T test in 95% confidence level. Results It was obvious in the study that depression, severe anxiety, severe neglect patients, severe obsessive-compulsive, interpersonal sensitivity, extreme aggression, paranoid ideation, severe phobias and psychosis, severe mental health problems in this population S162 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall is comprised respectively. There was a significant relationship between psychological health with marriage status and duration of addiction. (p>0.05). Conclusion Regarding to the Results, addiction is a multifactor phenomenon that impact on all of socio-psychological conditions, and to have effective preventive intervention, it need to integrate individual, family, and health providers’ cooperation, simultaneously. Keywords Psychological Dimensions, Addicts, Health Settings, Urmia, Iran. Study of Knowledge & Practice of Male High School Students in Urmia Nader Aghakhani1, Nader Aghakhani2, Ali Eftekhari3, Abbas Zarei4, Narges Rahbar5 1. Urmia University of Medical Sciences, Urmia, Iran 2. Urmia University of Medical Sciences, Urmia, Iran 3. Legal Medicine Research Center in Urmia, Iran. 4. Legal Medicine Research Center in Urmia, Iran. 5. Faculty of Nursing of Urmia University of Medical Sciences, Nazloo Road, Urmia, Iran Background and Aim As a dangerous phenomenon, addiction threatens adolescents and requires a comprehensive vision that specialists and researchers should be involved. There is not a detailed study about the factors at the onset of addiction based on cultural and economic in Urmia, Iran, the study about this title was performed to determine Knowledge & Practice of Male High School Students in District One & Two about Addiction in Urmia. Methods In this descriptive and analytical study, 306 students who were selected based on the multistage cluster sampling were analysed by using student’s t. test were studied by a questionnaire that its content validity confirmed by experts and the members of the scientific board and reliability was confirmed by test of internal index. Results In this study, most of samples mentioned that they introduced their friends to the parents that show the control on their relatoons with others that is important to prevent addiction in the youth. Demographic charactristics like age, settlement, average of marks, and education level of parents had a significant relation with knowledge & practice of male highschool students about addiction (p>0.05). Conclusion Regarding to the Results, knowledge in students is fairly good, an effective and preventive intervention is necessary to promote their knowledge that needs to integrate individual, family, school, peers, and neighborhoods factors, simultaneously. It should be concern in conducting prevention programs. Keywords Knowledge, Practice, High School Students, Addiction, Urmia The NEO-Five Factor Indicators and Adult ADHD Rating the Anticipated Return of Addicts Vida Aghazadeh1, Behzad Asbaghi2, Zahra Babazadeh3, Najibe Najafi4 1. Yong Researchers club, Ardabil Branch, Islamic Azad University, Ardabil, Iran. 2. Department of Clinical Psychology, Ardabil Branch, Islamic Azad University, Ardabil, Iran. 3. Department of Clinical Psychology, Ardabil Branch, Islamic Azad University, Ardabil, Iran. 4. Department of Clinical Psychology, Ardabil Branch, Islamic Azad University, Ardabil, Iran. Background and Aim The purpose of this study, the NEO-Five Factor indicators and adult ADHD rating was anticipated return in addicts. Methods The population of the study drug addiction clinic in Tabriz in 2014 with a mean age (20 to 40) were formed. The number 60 was chosen sampling method, respectively, 26% of glass, 22% of heroin, and 11 percent were taking opium. Data collected from the questionnaire, the NEO Five-Factor personality (NEO-EFI), the Conner’s Adult ADHD Rating Scales PCAARS-S: SV, and return to drug questionnaire used. Data using Pearson correlation and linear regression, and SPSS 16 were analyzed. Results The findings showed that ADHD significant level (P value <0/04) and Neo indices, the index of agreeableness (P value <0/023), return in addict the two-level power consumption and desires linearly predict. beween other indicators Neo significant relation between the variables did not exist. Also a significant correlation between ADHD and neuroticism index, respectively, with a significance level (P value <0/04), and (P value <0/028), with return in Addict existed. Conclusion The study shows index of agreeableness and ADHD rating return to predict drug involved and these variables can be used as a marker for increased rehabilitation for addicts return into drug use. Keywords The NEO-Five Factor Indicators, Adult ADHD Rating, Return of Addict. Comparison of Alexithymia and Depression between Addicts and Healthy Subjects Vida Aghazadeh1, Behzad Asbaghi2 1. Yong Researchers club, Ardabil Branch, Islamic Azad University, Ardabil, Iran. 2. Department of Clinical Psychology, Ardabil Branch, Islamic Azad University, Ardabil, Iran. Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S163 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Background and Aim Aim: This study compared the Alexithymia and Depression between addicts and healthy people. Methods The study sample addicts referring to addiction camps in Tabriz in 2014 with a mean age (18 to 55) were formed. A total of 122 patients (60 addicts and 62 healthy subjects) were selected for sampling. Data collected from the questionnaire, the Toronto Alexithymia Scale -20 (FTAS), and depression scale (DASS), were used. Data with Mean and Independent T-test and SPSS 16 were analyzed. Results The Results showed that the alexithymia addicts and control group, a significant differences) P value< 0/000(, addicts mean (M = 66.96) and control group (M = 48.57). And there was significant difference between two group in depression scale (P value <0/000), and mean in addicts and control group was respectively (M = 18.07), (M = 10.93). Conclusion This study shows that significant differences in alexithymia and depression between addicts and healthy people. Keywords Alexithymia , Depression , Addicts. The Primary Exploration of Sexual Dysfunctions of Men Who were Infected with Substance Abuse Laudanum under the Methadone Maintenance Therapy Hossein Aghazadeh vazifekhah1, Mehdi Sedghi2, Saeede Sanee3, Rozna Asgharnejhad4 1. Master of Clinical Psychology, Islamic Azad University of East Azarbayjan Science and Research Branch. 2. Master of Clinical Psychology, Islamic Azad University of East Azarbayjan Science and Research Branch. Young Researchers And Elite Club, Tabriz 3. B.A of General Psychology- P.N.U University of Fariman- Khorasan Razavi 4. Master of Clinical Psychology, Islamic Azad University of East Azarbayjan Science and Research Branch. Young Researchers And Elite Club, Tabriz Background and Aim The sexual dysfunction is one the most common problems which people who are dependent to laudanum substance are included. So, the goal of the present study is the primary exploration of sexual dysfunction in a group of patients who depended on laudanum under the treatment of Methadone preserving and after 6 months Methods The present research is a temporary research. 30 patients who were dependent on laudanum were selected from Kosar clinic in Tabriz and evaluated. At first, the demography information of patients was gathered, and then the sexual application of patients was evaluated before and after the treatment by the international index of the erection application Results The erection application showed the middle improvement by increasing the, while the sexual status was improved completely. The level of the sexual desire and the score of the sexual satisfaction were improved in slight, while the orgasmic function was not improved Conclusion The Results of study showed the outbreak of sexual dysfunction and the improvement of some factors through the treatment. Results show that on interring the treatment, the patients should be evaluated in sexual problems points of view; therefore, the great studies and investigations are needed to explore the other factors’ roles. Keywords Sexual Dysfunction, Laudanum, Methadone Maintenance Therapy Effect of Physical Training and its Components on Smoking S SOMAYEH Ahamdi1, Somayeh Ahmadi2, Ayyub Sheikhi3, Reza Kazemi4 1. Department of Physical Training, Science and Research Branch, Azad Univ., Kerman 2. Department of Physical Training, Science and Research Branch, Azad Univ., Kerman 3. Department of Statistics, Shahid Bahonar University, Kerman, Iran 4. Department of Physical Education, Valiasr University, Rafsanjan, Iran Background and Aim Smoking has been recognized to be a risk factor for progression of disease and kills about 5.4 million people a year, an average of one person every six seconds. Research on smoking and physical activity provides strong evidence of smoking’s negative impact and physical activity’s positive impact on long-term health. Many researchers pointed out that Regular use of tobacco products leads to addiction in many users. So, physical training can be used as a type of therapy to prevent people, especially young adult students, from smoking. The aim of this study is to assess the effect of physical training and its components, i.e., environmental training facilities and motivation of students, on their tendency to smoking cessation between students of physical education in Rafsanjan city. Methods The research method was correlational. The research population consisted of all students of physical education, Rafsanjan city in the academic year 2013-14 (1392-93s.c.). From among them 214 were selected via cluster random sampling and filled a Researcher-build questionnaires. Results Structural Equation Modeling (SEM) and Confirmatory Factor Analysis (CFA) were used to determine factors using SPSS20 and Amos Graphic 22. Path Analysis had been conducted to obtain the best fit model of SEM. The fitness parameters of the modified model (chi-square: 3.15, goodness of fit: .91, normal fit index:.93, root mean square error of approximation: .06 and comparative fit index: .95) indicated its suitability as the research model. S164 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Conclusion Physical training should be improved to prevent people especially young adult students, from smoking. Meanwhile, increasing the motivation of students and preparation of suitable training facilities will decrease tendency to smoking. Keywords Addiction - Smoking- Motivation - Structural Equation Modeling A Comparison of Defense Mechanisms, Dysfunctional Attitudes and Self-esteem among Glass Addicted and Non- Addicted People zohreh Ahangar Ghorbani1, Abbas Ali Hossein Khanzadeh2 1. M.A. in Psychology, University of Guilan 2. Assistant Professor of Psychology, University of Guilan Nafiseh Ahmadi1, Parvaneh Sarkeshikzadeh2, Hassan Mirza Hosseini3, Abolfazl Amirian4, Mohammad Taghi Rajabi5, Sayed Jafar Mir Hosseini6 1. MA in General Psychology Allameh Tabatabai University 2. Ma in Psychology 3. Department of Psychology, Islamic Azad University, Qom 4. MA in Psychology 5. Bachelor of General Biology 6. Bachelor of Science Background and Aim The main aim of this study was to examine the effectiveness of training health programs on prevention of addiction in high school students in the 90-91 academic year in Qom. Methods Background and Aim Addiction as a social crisis has many negative psychological consequences in society. Previous studies have suggested relationship among dysfunctional attitudes, defense mechanisms and self -esteem. This factors could cause depression, similar disorders and finally tendency to addiction The aim of this study was conducted to compare the defense mechanisms, dysfunctional attitudes and self-esteem among persons with glass addiction and non-addicted people. Methods The method of this research was causal-comparative. The sample consisted of two groups, 60 persons of people with glass addiction and 60 non-addicted people. Two groups were matched in terms of gender and age. The Defense mechanisms questioner (Andrews and et al, 1993), Self-Esteem Scale (Rosenberg, 1965) and the Dysfunctional Attitudes Scale (Beck and Weismann, 1978) were completed by participants. Data analysis was conducted using independent-t test and analysis of variance. Results The Results showed that there is significant difference in the defense mechanisms, dysfunctional attitudes and self-esteem among two groups of with grass addiction and non-addicted people. The result of independent-t test between two groups showed that the persons with addiction had more dysfunctional attitudes and poorly self-esteem when compared with non-addicted people. Also, based on analysis of variance, persons with addiction exhibited more used the neurotic and immature style. Conclusion According to the Results of this research, dysfunctional attitudes, self-esteem and defense mechanisms can to be important factors for predict, realize and effective therapy in addiction. Keywords The Effectiveness of Training Health Programs on the Prevention of Addiction in High School Students in Qom Defense Mechanisms, Dysfunctional Attitudes, Self-Esteem The research method used was semi-experimental with pre -test - post-test and control groups design. The population consisted of all high school students in Qom with 358 (176 males and 182 females ) of the randomly selected using clustering technique and divided into two experimental and control groups. The experimental group received 10 sessions of training health promoters. Inventory APS (Addiction Preparation Scale) as a pre-test and post-test were used for both groups. Results Showed that health promoting educational programs were effective in decreasing students’ tendency to drug abuse, active tendency and passive tendency. Further studies of the effectiveness of educational programs on males and females showed that health promoting educational programs were effective in decreasing female students’ active and passive tendency to drug abuse. They were not effective on male students. Conclusion Health promoting educational programs is effective in decreasing students’ tendency to drug abuse, active tendency and passive tendency. Keywords Health Promoters, Prevention of Addiction, Active Tendency to Addiction,, Passive Tendency to Addiction. Study of High School Students’ Knowledge in the Field of Addiction and Psychoactive Drugs In Order to Design Preventive Training Programs in Noor Abad Mamasani City Education. Nahid Ahmadi1, Hasan Maleki2, Esmaeel Sadipour3, Seyede Maryam Noormohamadi 4 1. MA in Educational Planning: Allame Tabatabaee University. 2. PhD in Educational Planning, Academic Member of Allame Tabatabaee university. 3. PhD in Educational Psychology, Academic Member of Allame Tabatabaee University. Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S165 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Background and Aim Drug addiction is one of the most important social problems that is decline in human societies and the institution of family breakdown, divorce, murder, suicide, robbery, being orphaned children, AIDS and other social harm. This study aimed to Study of high school students’ knowledge in the field of addiction and psychoactive drugs In order to design preventive training programs in Noor Abad mamasani city education done. Methods This is a descriptive study.The population that is consisted of all boys and girls high school students in the academic year 92-93 Nurabad mamasani city which between them 350 were randomly selected as the sample. Research tools, test from the Addiction National Institute and Drug Abuse America and have 6 units. Results The Results showed that students’ knowledge about addiction, drugs and their side effects is low, but awareness of drug marijuana is the least. Conclusion According to the Results of the present study should be noted that Best goal of the community to prevent and reduce drug demand, is Training and awareness of contacts, particularly students and students. Keywords Knowledge, High School Students’ ,Addiction. Results The Role of Thought Suppression, the Meta-Cognitive Factors and Negative Tensions in Predicting the Drug Dependency Disorder Conclusion Amir Ahmadi1, Babak Mohammadi2, Saeede Sanee3, Mahdi Zare4 1. Master of Clinical Psychology, Islamic Azad University of East Azarbayjan Science and Research Branch. Young Researchers And Elite Club, Tabriz 2. Master of Clinical Psychology, Islamic Azad University of Ardabil Science and Research Branch. Young Researchers And Elite Club, Tabriz 3. B.A of General Psychology- P.N.U University of Fariman- Khorasan Razavi 4. Master of Clinical Psychology, Islamic Azad University of East Azarbayjan Science and Research Branch. Young Researchers And Elite Club, Tabriz The Results showed that the level of knowledge in the unit 6, is very low. The situation is far from satisfactory knowledge; Also, information and knowledge in all six of the unit, with no significant difference. According to the Results of the present study should be noted that Best goal of the community to prevent and reduce drug demand, is Training and awareness of contacts, particularly students and students. Keywords knowledge, addiction and psychoactive drugs ,preventive training programs Survey of high school students’ knowledge in the field of addiction Nahid Ahmadi1, Hasan Maleki2, Esmaeel Sadipour3, Seyede Maryam Noormohamadi4 1. MA in Educational Planning, University of Allameh tabatabaee 2. phd in Educational planing, academic member of Allame tabatabaee university. 3. phd in Educational psychology, academic member of Allame tabatabaee university. 4. MA in clinical psychology, University of Allameh tabatabaee Background and Aim Addiction is one of the injuries and problems of the modern world that Form taken a risky and very complicated at the same time, the spread is global. This study aimed to Survey of high school students’ knowledge in the field of addiction done. Methods This is a descriptive study.The population that is consisted of all boys and girls high school students in the academic year 92-93 Nurabad mamasani city which between them 350 were randomly selected as the sample. To assess the level of awareness of drugs, used of Questionnaire Addiction and Substance Abuse America the farmer is the norm in 1390, the level of knowledge with respect to nicotine, cocaine, alcohol, cannabis, heroin, marijuana and club drugs measures. Background and Aim The goal of the present research is to investigate the role of thought suppression, meta-cognitive factors and the negative tensions in predicting the drug dependency disorder Methods The research plan in one side is solidarity and by attention to the other goal it is causative- comparative. The samples of the research were 70 populations who were infected with the drug dependency disorder and 70 populations were normal people. The people who were dependent to drug were selected from the men who referred to an outpatient treatment center and the normal samples were selected from normal population. The sampling method in both methods was accessible. Two groups’ people were evaluated by using meta-cognitive questioner, white bear suppression inventory and the anxiety and depression questioners. For analyzing the data, the recognizing analysis was used Results The negative meta-cognition believes about concern, depression and thought suppression had the highest power of significant predicting of the drug dependency disorder. Conclusion It is possible to predict the dependence to the drug disorder by using the meta-cognitive factors, thought suppression and negative emotions, the drug dependency disorder. In base of this plan, it is possible to supply the prevention approach from drug dependency and a psychotherapy approach in base of cognitive and meta-cognitive therapy and to use the S166 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Results Of the present research in the environment and clinical consultation for helping the people who are dependent to drug Keywords Self-Regulatory Executive Function Model, Meta-Cognitive Believes, Thought Suppression, Drug Dependency Keywords Life Skill, Avoiding, Get Further Into Drug, University Students. Evaluation of Impulsivity of Cognitive Flexibility Base on Type of Consumptive Dugs in Substance Dependent Individuals Influence of Teaching Life Skills Programs for Avoiding of Drug Taking on University Student Teymor Ahmadi1, Atefe VahediGajari2, Seyed Yousof Seyednezad Jeludar3 1. Islamic Azad University,Qhaemshahr Branch , Young Researchers Club, Qhaemshahr, Iran 2. Staff of Educational, Babol, Babol, Iran 3. Staff of Educational, Babol, Babol, Iran Background and Aim Impulsivity is a core element of plenty of individual and social deficits. The purpose of this study is to evaluation impulsiveness and cognitive flexibility based on the type of drug- addicted people. Methods Background and Aim Background and Objective: life’s skill because of great theory and researching background is very important in avoiding of getting further into drug. “Teaching life skill’s s” collection by Dr.Botvin is the same and tries by contrasting sense of person to increase great self-independency and self-confidence. It is an important key on taking drug. Because there is no influence avoiding program on universities, we verified this program on this research. life’s skill because of great theory and researching background is very important in avoiding of getting further into drug. “Teaching life skill’s s” collection by Dr.Botvin is the same and tries by contrasting sense of person to increase great self-independency and self-confidence. It is an important key on taking drug. Because there is no influence avoiding program on universities, we verified this program on this research. Methods All university student of Payam noor, Babol branch on the years of 2014-2015 are of research collection. Research sample of about 100 girl and boys student were chosen and divided on two 50 persons groups. (Control and testing) testing group students passed life skills course but the other did not passed. The two groups were compared by health and good behavior of Dr.Botvin’s Questionnaires and on the base of dependent and independent group of T-teaching statistic. Results The mean score of university student have had differences to the scores on pre-testing phase. Because after- testing we had increasing information about materials, changing attitude to material and increasing skills. Conclusion Fariba Ahmadian1, Zahra Rashid Tavallaie2 1. Zahedan University of Medical Science 2. Zahedan University of Medical Science Teaching life skills increased testing group’s skills level. In this case, this program is an avoiding factor and decrease drug taking on future. Teaching life skills collection is an avoiding factor on drug taking.We propos to teach this as an optional course on all universities. To do research on all other factor on life skills and noticing to time of teaching (long term, short term) is very interesting. The present study is descriptive cross-sectional .The sample consisted of 80 substance dependence. Baratt Impulsiveness Scale and Wisconsin Card Sorting Test were used. We used ANOVA and Kruskal-Wallis to analyze the data. Results The finding indicated there is a Significant difference between Drug and impulsivity, groups of Hashish and Crystal had the highest score impulsiveness (P < 0/05). Also, there is no statistically Significant difference between Drug and cognitive flexibility ,but group using hashish and crystal had the highest score cognitive flexibility (P < 0/05). Conclusion This study showed that using hashish and crystal in comparison with other drugs ,can be leading to greater impulsiveness in people ,and taking these drugs can damage to neuropsychological functions related to the cognitive flexibility of the frontal lobe. Keywords Impulsivity, Cognitive Felexibility, Substance Dependent Individuals The Relationship between Narcotic Substance Abuse and Duration of Exclusive Breast Feeding Mothers Hoda Ahmari Tehran1, Rogieh Javan2, Yaser Tabaraei3, Maryam Yavari4, Maryam Hashemian5 1. Faculty of Midwifery,Research Center for Medicine and Religions, Qom University of Medical Sciences, Qom, Iran 2. General Practitioner, Sabzevar University of Medical Science, Sabzevar ,Iran 3. Department of Biostatistics, Faculty of Health, Sabzevar University of Medical Sciences, Sabzevar, Iran. 4. Msc of Medical Education .Hospital Shahid Beheshti .Kashan University of Medical Sciences. 5. Msc of General Health, Faculty of Health Center, Sabzevar University of Medical Science, Sabzevar ,Iran Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S167 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Background and Aim Today substance abuse is a major health problem in many population groups, such as mothers and their newborns are put at serious risk. Since breast-fed infants is an important need for which can be affected by many factors such as substance abuse This study aimed to determine the association between drug abuse and duration of exclusive breastfeeding was the mother city of Sabzevar Methods The study was a cohort study. In order to assess the nutritional status of 75 pregnant women exclusively breastfeeding for 2, 4 and 6 months of age infants were studied. Data Analysis was done using SPSS.Confidence coefficient of 95% was considered. Results 31/4% of mothers who substance abuses have had exclusive breastfeeding up to 6 months. 85% of mothers who not substance abuses have had exclusive breastfeeding up to 6 months. The feeding status at 2 and 4 months of age was significantly different between the two groups (P=0/0001). Conclusion Drug use by the mother during pregnancy and lactation can reduce the duration of exclusive breast feeding .Therefore; preventive educational programs during pregnancy should focus on reduction and elimination of using such drugs. Keywords Narcotic Substance Abuse , Breast Feeding , Mothers The Association between Narcotic Substance Abuse and Duration of Exclusive Breast Feeding Mothers Hoda Ahmari Tehran1, Roghieh Javan2, Yaser Tabaraei3, Maryam Yavari4, Maryam Hashemian5 1. Faculty of Midwifery,Research Center for Medicine and Religions, Qom University of Medical Sciences, Qom, Iran 2. General Practitioner, Sabzevar University of Medical Science, Sabzevar ,Iran 3. Department of Biostatistics, Faculty of Health, Sabzevar University of Medical Sciences, Sabzevar, Iran. 4. MSc of Medical Education .Hospital Shahid Beheshti .Kashan University of Medical Sciences. 5. MSc of General Health, Faculty of Health Center, Sabzevar University of Medical Science, Sabzevar ,Iran Background and Aim Today substance abuse is a major health problem in many population groups, such as mothers and their newborns are put at serious risk. Since breast-fed infants is an important need for which can be affected by many factors such as substance abuse This study aimed to determine the association between drug abuse and duration of exclusive breastfeeding was the mother city of Sabzevar Methods The study was a cohort study. In order to assess the nutritional status of 75 pregnant women exclusively breastfeeding for 2, 4 and 6 months of age infants were studied. Data Analysis was done using SPSS.Confidence coefficient of 95% was considered. Results 31/4% of mothers who substance abuses have had exclusive breastfeeding up to 6 months. 85% of mothers who not substance abuses have had exclusive breastfeeding up to 6 months. The feeding status at 2 and 4 months of age was significantly different between the two groups (P=0/0001). Conclusion Drug use by the mother during pregnancy and lactation can reduce the duration of exclusive breast feeding .Therefore; preventive educational programs during pregnancy should focus on reduction and elimination of using such drugs. Keywords Narcotic Substance Abuse , Breast Feeding , Mothers How Abuse is Related to Methadone Maintenance Tratment Outcomes Elaheh Ahounbar1, Behrouz Dolatshahi2, Ali Farhoudian3 1. Clinical Psychology Dept., University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 2. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran, Clinical Psychology Dept., University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 3. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran Background and Aim More than half of substance abusers entering addiction treatment report a history of physical or sexual abuse. It is unclear if such a history impacts treatment outcomes. (1) This study investigates the prevalence and effective variables on men with sexual, emotional and physical abuse histories who were treated at an outpatient methadone treatment program. Methods Opioid-dependent, methadone-maintained patients were recruited in the present study. A structured abuse questionnaire was used, in order to assess the life time prevalence and effective variables on men with sexual, emotional and physical abuse histories, during Methadone Maintenance Treatment (MMT) admission. Results An extremely high portion of participants experienced sexual, emotional and physical abuse histories. The highest level of abuse was found to be emotional(76%), and sexual abuse was reported least among three kinds of abuse evaluated (27%). Conclusion In this study of opiate-dependent men who participated in outpatient methadone treatment, we see evidence that many clients experienced sexual, emotional and physical abuse histories and with regard to behavioral and emotional functioning, patients with an abuse history reported significantly more problems in the psychiatric and family domains upon initiation of treatment as compared with those without an abuse history. S168 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Keywords Sexual, Emotional and Physical Abuse - Methadone Maintanace Treatment Prevalance of Birth Orders in People with Opioid use Disorders Elaheh Ahounbar , Behrouz Dolatshahi , Ali Farhoudian 1. Clinical Psychology Dept., University of social welfare and rehabilitation sciences, Tehran, Iran 2. Clinical Psychology Dept., University of social welfare and rehabilitation sciences, Tehran, Iran, Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 3. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 1 2 3 Background and Aim The study of birth order in substance related disorders is crucial. First, past research in this area was short-lived creating the need to revive it. Second, literature suggests that very few studies investigated the phenomenon making it difficult to conclude whether a birth order effect exists (Weeks & Newlon 1984; Lerner & Linder 1975; Smart 1963; Schachter 1959). Methods The study included 100 participants from different MMT centers in Tehran, Iran. All the participants were male and their age ranged from 25 to 60 years of age. An interview was used to collect information concerning the participant’s birth order. is an unavoidable part of human life. On the other hand, soothing the stress can immune people against mental disorders and diseases specially drug addiction? The goal of this research is to investigate mental toughness with and strategies to calm down the stress among HIV afflicted male prisoners Methods This research in descriptive and mental toughness the community of research consists of all male drug addicted prisoners in the camp of Kermanshah. By simple random sampling, 120 drugs addicted as samples. Then, COOBASA questionnaire (1984) and LAZAROOS and FALKMAN strategies (1985) were distributed among the addicted people and obtained information was analyzed by SPSS. Results Considering the analyzed data, we find that there is a significant relation between the mental toughness with strategies of Problemfocused and emotion-focused. Conclusion Considering the Results, we find that are those challenges, committed and qualified to know more manageable, less stressful and threatening to evaluate the benefit of more effective coping skills And contrary to what people uncontrollable circumstances threatens to assess coping strategies less. Keywords Prisoners, HIV Afflicted, Mental Toughness Results Since the aim of the research was to assess whether particular ordinal birth orders were more prevalent than others when it comes to substance related disorders. Descriptive statistics were used to investigate the objectives of the study. The majority of patients were the last child of family (67%). Their mean number of siblings was 5 ± 2 (range 20–70 years of age). Conclusion From the descriptive statistics noted above, it was evident that most of the population sampled was characterized by participants who were youngest children from their families of origin. All in all, the Results illustrate that indeed birth order does play a role when it comes to addiction. Keywords Birth Orders, Opioid use Disorders Investigation on Psychological Mental Toughness and Strategies to Calm Down the Stress among HIV Afflicted Male Prisoners Ajdare Asaddagi1, Reza Akbari2, Abozare Azimi3 1. M A in Management 2. M.A in Counselling Psychobiology 3. M A in Education Psychology Background and Aim Studying the Effectiveness of Group therapy “Cognitive-Behavior” and “Stages of Change” on Craving Heroin Addicts in Kabul Sayyed Hussain Hussaini1, Sediqa Akbari2 1. Teacher, Departent of Psychology, Education University Kabul, Kabul, Afghanistan 2. Department of Clinical Psychology, Shiraz University, Iran. Background and Aim A high number of people suffer from addiction in Afghanistan. Existing treatment provision is still dominated by residential and home based approaches which focus on detoxification, residential rehabilitation and low-intensity aftercare. Treatment must shift to more evidence-based modalities such as structured psychosocial interventions, as international research proves they yield better treatment outcomes including a lower rate of relapse and improvements in social functioning. The main objective of this research is “Studying the effectiveness of Group therapy “Cognitive-Behavior” and “Stages of Change” on heroin craving among in-treatment heroin abusers in Kabul”. Methods Nowadays, stress and neural pressure are widespread and stress This fundamental research-application is a quasi-experimental study on 42 heroin addicts male conducted in summer 1392. 42 addicted male individuals assigned into two experimental groups; Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S169 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall CBT (13 persons), Change stages (14 persons) and a control group (15 persons). The Change Stages and CBT groups received 8 ninety minutes long intervention sessions. The control groups received nothing. A Heroin Craving Questionnaire (HCQ) was administrated to assess craving to heroin use before and after intervention. Data was analyzed using ANCOVA method. Results CBT and Change stages experimental group rather than control group had differences significantly in craving to heroin use. However, there was no difference between the effectiveness two types of interventions. Conclusion Cognitive behavior therapy is based on beliefs; Change stages intervention is based on motivational structures. Many researches were supporting as effective psychotherapy methods in the world. So, both of CBT and Change stages are new and effective methods as evidence-based therapy in drug abuse treatment in Afghanistan. Keywords Cognitive Behavior Therapy (CBT); Stages of Change; Group Therapy; Craving; Heroin; Motivation Reviewing the Causes of Epidemiology and Industrial Addiction Students Applying Preventive Mohamad Akbari1 1. Hospital Staff Najaf Abad Fateme Zahra of Social Security - Prevent Instructors Barking Culture Parsfarhang Center Background and Aim Problem: Today, not only in Iran but in the epidemiology and etiology of numerous studieson student target population has been But incidence of drug addiction and provoke much speculation in the industry Addiction phenomena that arise victimization (crime victim) is effective Drug Addictive orientation bias in consumption patterns among college students need to explain the prevalence and etiology addiction The purpose of this research brief evaluation of studen Student Hype t prevalence emphasizing the underlying Probable risk factor That Significant correlation between Industrial (ice)Materials addictive University of Southern California (UCLA, etc), is present Finally preventive is practices (Marilyn (Marilyn, etc.) Methods Methods A review of the new approach is to study that 8 reviews important research and other resources with a brief summary of risk factors The prevalence rate among students in the traditional drugs are estimated as a percentage Results Rigorous screening has not done to students about drugs and quasi-drugs Drug Industry material such as addictive drugs (Ritalin) and hookah smoking Although the incidence of drug abuse among students is very troubling Not worrying but the stress system. Lifestyle and especially null and positive beliefs Industrial materials and medicines to some one hand and rapid spread Regardless of gender, legal materials, such as cigarettes and shisha (range 15 to 21.1 percent) as the gateway drug of concern and is attention Conclusion The best method of prevention methods are based on the consumption patterns of and risk factors based particularity Rectifier (Low stamina Obtain energy) is the target group of students Cortical Precautionary models must include precautionary principle and interactive contingency This article reviews some research on college campuses will attempt to present recommendations for the preventive model Keywords Prevalence and Etiology Student Hype Materials Addictive prevention, Risk Factors Brain Imaging and Treatment Interventions Mohamad Akbari1 1. Mohammad Akbari PharmD Student in Pharmaceutical Sciences Of Hospital Socialworker - Instructor Prevent Kanun Pars Farhang Culture Center Background and Aim Introduction: MAMP addictive substance is easier than amphetamine was built in 1919 in Japan and 1 950 were used amphetamines in treating severe depression. Problem: The duration of the treatment, monitoring and withdrawal from drugs a nd other atherapies bottle of challenges, the recovery of ice addiction(meth amphetamines) a lengthy process and at each stage, the patient may experience certain symptoms and problems Failure to inform the patient of his or her progress Recovery lead to fatigue and frustration To be able to deal with potential problems and effective intervention can be planned. General purpose: To evaluate the applicability of the idea of non-invasive brain imaging Motivational interviewing is a new attitude and matrix methods(mrs.mri.EE G pets .spet) Methods are reviewed That and qualitative methods which can be Results Early stages of recovery skills, knowledge of development disease relapse temptations andobjective methods of brain imaging sensor Illustration objective medical team can help Program objective perception of improvement and progress toImages of the brain, avoiding the temptation of short-term risk in the first week of a monthb will determine In the poisoning long term is also used to avoid poisoning such depression withdrawal symptoms and decreased the Vmax receptor limbic dopamine and Non-dopamine pet.spect Prefrontal shows the relevant portions of the limbic pleasure seeking as part of logical thinking rational and orbital frontal damage is shown after one month abstinence Conclusion Brain imaging using pharmacologic interventions making it possible to design and effective medication protocols, follow-up S170 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall and monitoring to provide medical Non-pharmacological interventions in the management of cognitive and behavioral therapy techniques, and evaluation matrix times of temptation Prove the treatment of recurrent periods of critical illness Avoiding Addicts imaging is useful to the psychologist and consultant The idea of basic research and applied research, and qualitative case study of drugs and otherinterventions will be Keywords Methamphetamine, Brain imaging, Interventions, Monitoring ions and lack of happiness can be regarded as a criteria for propensity of the addiction. Also from the both groups point of view political challenges can have a very small effect for propensity of it and usability for decelerating the emotions or difficulties can cause propensity for the addiction. The camp groups and students had different ideas, but it is not significant meaning. From the both groups point of view, the family’s mental health can be effective in decreasing the propensity to the fix and accompanying with bum friends can be up to high level regarded as a criteria for propensity of addiction. Conclusion Investigate the Relationship between the Amount of the Familys Anarchy and Propensity to the Addiction in the Damghan’s Payamenoor University and Camp (the Samans Deduction Damage Institute) in the S Mohammad Akbari , Hosin Abrahimi , Masomeh Alamoutiniya 1. Azad Univarsity 2. Azad University Shahrood 3. Azad University Shahrood 1 2 3 Keywords Addiction, Accomplishment and Human Value, Spiritual, Ethical Social Anarchy. Use of Ritalin among Students, a Systematic Review Background and Aim Today, rarely we can find a country who weather from addiction problem and did not all cater various price. it is obvious that en country this huge predicament will be useful which is accompany with scientific invasion from its different perspective. human and societies which forget accomplishments and human values and with the excuse of freedom and liberality stick from the God’s servitude and slavery of party, nationality, pylon and even worse gravitate to their own concupiscence, achieved a abjection humility, so they encounter with different spiritual, ethical and social investigate the relationship between the amount of the familys anarchy and propensity to the addiction in the Damghan’s Payamenoor university and camp (the Samans deduction damage institute) in the Shahrood city this research in the level of Damghan’s Payamenoor university and of the Shahrood’s camp can be an effective step for recognizing the reason for propensity to the addiction. The research population included the student’s who were studying at Damghan’s Payamenoor university and the Shahrood’s camp which we choose 50 people with this sample population’s and we have chosen the final analysis the descriptive method such a research in the university level and camp can be an effective step in recognizing the reason for addiction. Methods In the present research a method has been chosen which the necessary accuracy, aggrades the way for doing the similar and comprehensive research. Descriptive research is a definite and specific research process which its aim meaning the real and regular characteristics or a subject. The research aim that report whatever is it without any interferential and conceptual deduction. Results the result of this research shows that probably one of the elements can have a positive role in the people’s propensity to the addition, which is caused by the anderfin’s recreation in the brain which the people shelter to it naturally and unintentionally for securing it. The sample groups (student and camp) according to the chi do test result for answering the research question had similar opin- Mohammad Akbari kaji1, Jafar Moghaddasi 2, Sedigheh Farzi 3, Esmaeil Mohammad Nejad 4 1. PhD Student of Nursing in Isfahan University of Medical Sciences. Member of Young Reserchers Club, Islamic Azad University Khoorasgan branch, Khoorasgan, Esfahan , Iran 2. PhD Student of Nursing,Isfahan University of Medical Sciences, Faculty Member of Shahrekord University , shahrekord,Iran 3. PhD Student of Nursing,Isfahan University of Medical Sciences, Faculty of Nursing and Midwifery,Isfahan,Iran 4. PhD Student of Nursing, International Branch, Shahid Beheshti University of Medical Sciences, Tehran, Iran Background and Aim Although methylphenidate(Ritalin) is considered first-line pharmacotherapy for the treatment of attention deficit hyperactivity disorder (ADHD) , it has potential for abuse and diversion . The licit and illicit use of methylphenidate has increased dramatically over the past 10 years specially in student . The use of Methylphenidate for cognitive enhancement is a subject that has received much attention in the literature and academic circles in recent times globally. Medical doctors and medical students appear to be equally involved in the off-label use of Methylphenidate. Pharmacological neuroenhancement has increased in the academic environment, mainly among college students, to such an extent that the use of psychostimulating drugs to improve academic performance is considered a public health problem in various countries. Aim of this study is review the effects of methylphenidate on cognitive enhancement, memory, and performance in students Methods A review of six databases (ProQuest, PubMed ,scopus, iran medex , ScienceDirect, SID ) analyzing the abstract and full text of all articles published between 2010 to april 2014. We Search terms “methylphenidate”, “Ritalin”, “Ritalin-SR” . From 65 Results found in the mentioned databases, 18 articles were included in the final analysis Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S171 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Results Most students began using the drug after entering the university, and the reasons cited to justify it are related to enhancing academic performance. Ritalin simply increases wakefulness , alertness and reducing the time of sleep but any article not determined it is definitely effect on memory and learning or not ? it has side effect in long use or not ? More research is needed to promote understanding and awareness of this problem among student and the risk for substance use in different population and More educational programs regarding the use of methylphenidate are required and should be focused on the students Conclusion we don’t find any article in iran about this title and we have not any statistical for prevalence use of methylphenidate in student. Therfore the healthy responsible must have more attention to this subject. Keywords Methylphenidate, Ritalin , Ritalin-SR, Systematic Review Effects of Methamphetamine Use on Sexual Function and Male Fertility Pouran akhavan akbari1, Marefat Ghaffari Novin2, Farzaneh Zaheri3 1. Shahid Beheshti University of Medical Science-Tehran- Iran 2. Shahid Beheshti University of Medical Science-Tehran- Iran 3. Shahid Beheshti University of Medical Science-Tehran- Iran Background and Aim Exposure to drugs and toxins can play an important role in male infertility. Methamphetamine (MAMP) is a central nervous system stimulant that is increasingly abused especially by young adults. Sexual disorders are the most important effects of stimulants and addictive drugs. Regarding to the excessive use of methamphetamines (crystal) among men of reproductive age, this study aimed to investigate the effects of methamphetamines on sexual function and male fertility. Methods This article reviews the research on the methamphetamine effects on Sexual function and male fertility. A literature search was conducted in June 2014 using the electronic databases Google Scholar, PubMed, Scopus, Web of Science and SID. Search terms used were methamphetamine, fertility, men and reproduction. Results The studies of amphetamines on male fertility are modeled through animal studies. Studies showed that addictive stimulant drug use initially reinforced sexual function through reducing anxiety and raising the mood temporarily but continued use of drugs gradually decreased libido which is followed by Lack of sexual arousal, orgasm or ejaculation. Findings from animal and human experiments indicate that amphetamines can reduce sperm quality. Methamphetamine use caused inflammation in seminiferous tubules of male testes and decreased quantity and motility of sperm. In vitro and in vivo male rat studies showed that a single injection of amphetamine led to decreased plasma testosterone in a dose-dependent manner. Amphetamines Inhibited testosterone production by Gonadotropin reducing. Increasing Methamphetamine consumption, increased serum levels of LH and testosterone, while FSH concentrations decreased with increasing levels of methamphetamine. Studies have found that regular high doses consumption of methamphetamine decreased the number of mature sperm in the epididymis. Acute injection of methamphetamine at different doses (5, 10, or 15 mg/kg) induced apoptosis in seminiferous tubules in male mouse testis .Methamphetamines led to disruption of normal testicular homeostasis by reducing the reproductive cells and increased apoptosis of spermatogenic cells in the testes. Conclusion Use of methamphetamines is often during reproductive years or during critical periods of testicular development .Methamphetamine use affects the hormonal axis and causes impairments in semen analysis and functional sperm parameters. Negative effects of methamphetamine have been proved on male fertility, including sperm function and testicular structure. Keywords Methamphetamine, Fertility, Men, Reproduction Study of the Intra-Accumbal and Peripheral Effects of Memantine on Withdrawal Syndrome in Morphine-Dependent NMRI Male Mice Zeinab Akhtari1, Hedayat Sahrai2, Mahboobeh Kamali3 1. Neuroscience Research Center, Baqyiatallah University of Medical Science, Tehran, Iran. 2. Neuroscience Research Center, Baqyiatallah University of Medical Science, Tehran, Iran. 3. Department of Biology, Faculty of Sciences, Azad University, Tehran, Iran. Background and Aim Different investigations have showed a role for nucleus accumbens in animals’ response to morphine dependence. Methods Male NMRI mice (30g) were used. In a primary study, the effect of peripheral Memantine (0.1, 1, and 5 mg/kg) on withdrawal syndrome sings including number and the high of jumping and the amount of fecal material was investigated. In another groups, canulation was performed in the right, left or both sides of nucleus accumbens and seven days later, the effects of intra-accumbal memantine administration on morphine withdrawal was investigated. Results Our Results showed that peripheral memantine administration caused a reduction in the number and high of jumping in all doses used. The drug reduced the amount of fecal material in dose of 5 mg/kg. Memantine reduces the number and high of jumps when injected in right, left or both sides of nucleus accumbens. Conclusion In Conclusion, it seems that NMDA glutamate receptors within S172 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall the nucleus accumbens have a crucial role in withdrawal syndrome signs in morphine dependent mice. On the other hand, there is no difference between right or left sides of nucleus accumbens in this regard. Keywords Social Factors, Psychological Factors, Drug Use, Tehran Keywords Physical Dependence, Morphine, Nucleus Accumbens, Memantine Effect of Psycho-Social Factors on the Prevalence of Addiction in Tehran Hassan Ali Veiskarami1, Ezatollah Ghadampour2, Roghayeh Alaei Khoraem3, Sarah Alaei Khoraem4 1. Assistance Professor, The Department of Psychology, Lorestan University, Lorestan, Iran. 2. Assistance Professor, The Department of Psychology, Lorestan University, Lorestan, Iran. 3. PhD. student, The Department of Psychology, Lorestan University, Lorestan, Iran. 4. MA. The Department of Psychology,University of Mohaghegh Ardabili, Ardabil, Iran Background and Aim Addiction is a problem which should be considered of more social and psychological dimensions than the political and economic. The Results of some studies show that young adults and adolescents dealing with substance abuse are most involved in theft, violence, academic failure, disorganized thinking, reduced psycho-social adaptation, reduced the ability of problem solving, the high degree of social isolation and depression (Newcomb and al, 1998; Sussman et al, 1996). This study aimed to identify of psycho-social factors on the prevalence of addiction in Tehran. Methods This research method is qualitative, library and documentation has been collected through 12 in-depth interviews (with addicts) and five structured interviews (with staff associated with the drug). Results The Results of these interviews, after the coding and extraction components are the followings. the social factors are: lack of employment, unemployment and seasonal unemployment; income gap and the distance between the top, middle and lower-class society; the inability to subsistence; irresponsibility and indifference mode about everything; no education and social skills; addicted friends, unsafe families and unclean neighborhoods; easy access to drugs and the lack of a proper fight with its distribute; depending many families on the income from the retail drug and very high turnover for wholesalers. The psychological factors are: state of confusion and lack of peace; caught in complete boredom; stress and anxiety; lack of access to satisfy the needs and demands; ignorance and lack of knowledge about life skills, a sense of emotional loss and not to be in desired social status; not receiving the respect and self-esteem from others. Conclusion ate and effective coping with drug use. Therefore, these Results could have important impacts on training and consulting services. The main factors for substance use in social institutions are: the family, school, peers, community and the individual. The psychosocial factors have the greatest role in the prevalence of substance use in Tehran. The Results suggests that drug users )whether adults or adolescents( do not have mental and social skills for appropri- Women Treatment Seekers and Methamphetamine Use: the First Report from the Persian Gulf Region Zahra Alam Mehrjerdi1, Kate Dolan2, Abbas Deylamizade3 1. Program of International Research and Training, National Drug and Alcohol Research Centre, Faculty of Public Health & Community Medicine, University of New South Wales, Sydney, Australia 2. Program of International Research and Training, National Drug and Alcohol Research Centre, Faculty of Public Health & Community Medicine, University of New South Wales, Sydney, Australia 3. Rebirth Society (NGO), Tehran, Iran Background and Aim The transition from using opiates to methamphetamine is a newly emerged health problem among some Iranian opiate-dependent women. Yet, the underlying reasons associated with initial methamphetamine use are not well-studied especially among treatment seekers. Methods In 2011-2012, a cross-sectional survey was conducted at the largest women therapeutic community center in Tehran to explore the initial reasons associated with methamphetamine use. All women (N=500) were recruited and interviewed using a semi-structured questionnaire during one year. Results The mean age of the women was 31.8 (SD= 8.5) years old. Half of them were married (51.8%). The remaining respondents were separated or divorced. At admission, 30.2% of women reported making a transition to co-use of methamphetamine with other drugs. 30% of women were methamphetamine users while the remaining women were still opiate users. The mean year of dependence on methamphetamine use was 4 (SD=4.5) years. Initial reasons associated with methamphetamine use included curiosity, a desire for increased energy and job-related outcomes, increasing sexual performance, a desire for staying awake, self-treatment of depression and anxiety, increasing concentration, substituting opiate use with methamphetamine use, increasing mental abilities, a desire for being slim, and improving the quality of skin. Conclusion Methamphetamine use could have important clinical and treatment implications for some Iranian drug-dependent women. The initial reasons associated with this problem should be considered in designing and implementing drug education and prevention programs for this group. Keywords Iranian Women, Methamphetamine, Opiates, Treatment, Persian Gulf Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S173 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Examining the Predictive Role of Child Abuse Background and Perceived Social Support in Forecasting the Tendency of Youth to Addiction : a Case Study of Youth Aged 20 to 30 in Yasuj , Yazd and Kashan Anise Alfoone1, Nahid Akrami2, Maryam Naiemi3, Neda Lotfi4 1. Student 2. PHD 3. Student 4. Student Background and Aim The tendency to addiction is one the main challenges in nowadays society and necessary topics for research. In line with this need, examining the predictive factors of the addition could help preventing the addiction and misuse of addictive materials. Hence, the purpose of this study is examining the predictive role of child abuse background and perceived social support in predicting the youth (aged 20 to 30) tendency towards addition in Yasuj, Yazd, and Kashan. The hypothesis in this study is the predictive role of these variables for the tendency towards addiction. Methods The method of this study was correlation. The population of this study was the youth aged 20 to 30 in Yasuj, Yazd, and Kashan. The samples of the study were 150. From each city 50 participants were selected through simple random sampling and child abuse questionnaire, and tendency towards addiction and perceived social support questioners were distributed. To analyze the data, regression and SPSS were used to deterring the predictive role of perceived social support and child abuse in tendency towards the addiction. Results The findings of the study showed that both child abuse and perceived social support can predict youth aged 20 to 30 tendency towards addiction. According to the Results of child abuse questionnaire, physical child abuse is the strongest predictive factor for the tendency towards addiction in comparison with other types of child abuse. Conclusion Regarding the predictive role of child abuse background and perceived social support in tendency towards addiction, it could be expected that controlling child abuse and maximizing perceived social support can have a preventive role for tendency towards addiction in youth. Keywords Child abuse, Perceived Social Support, Tendency Towards Addiction, Youth Relation between Control Resource and Addiction. Hadi Aliabadi1, Fateme Rahnama2, Fateme Mirieskandari3, Reza Ghlekahe4 1. Tabatabaye Alame Tehran Iran 2. Slamik Azad University Torbate Jam Iran 3. Tabatabaye Alame Tehran Iran 4. Slamik Azad University Mashhad jam Iran Background and Aim Purpose of current research is relation between addiction and control resource. Methods The research method was correlational and statistical society was the addicted at clinics of Neyshabour city at 2013 that 70 individuals were selected by available sampling. Rater’s control resource questionnaire was used. Data was analyzed by correlational coefficient. Results The findings showed that there is significant relation between addiction and external control. Conclusion Results show the relation between addiction and control resource. Keywords Control Resource, Addiction, A Comparative Study of Factors Associated with Repeated Drug Addiction Treatment Center va Bakhtiari Groups in 1392 Reyhaneh Alikhany1, Davoud Zamani2 1. MSc 2. MSc Background and Aim One of the main issues and problems from the past and present, human society is threatening, abusive consumption and drug addiction phenomenon that has a variety of severe consequences in political, economic, social and psychological different levels of society between generations is young. Methods A cross sectional study of patients referred to the clinic for addiction Demographic information is performed . Units during the year were selected by convenience sampling method , data collection tool was a questionnaire .which included family factors , economic and personal , social and cultural Results The 258 patients , 244 patients ( 58/94 %) men and 14 ( 42/5 %) were female , mean age 85/7 ± 56/28 years and the mean age of S174 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall onset of addiction 24/5 ± 87/19 years and all of the addiction had more than one type of substance abuse . , and most consumables such opium , molasses, heroin , crack , crystal and hashish .had . The Results showed that 244 patients ( 100% ) subjects had a previous addiction and drug re- recorded the majority of them ( 76.8% ) having a mental illness ( signs symptoms psychosis depression ) , respectively. Demographic factors , relieve loneliness and isolation ( 44% ) , family factors , poor relationships with parents, children ( 38.85 %) in singles and inappropriate relationship with the wife of his wife and children , and misunderstanding , respectively ( 36.6 percent, 28.3 percent ) in the field of social factors are addicted friends ( 34.6 percent ) , economic factors , unemployment ( 58.9 percent ) and cultural factors , lack of healthy entertainment in their leisure time (41.4% ) of anglers and recreational drug use with ( 46.9% ) , respectively, were the most important reasons why Back to the smallest physical problems with drug use ( 1.3% ) with refractory disease ( 0.6 %) were formed. Conclusion the study Results indicated that Education, interpersonal relationships with clients and dealing with the patient’s family members after the cessation of drug use is essential And recommended authorities for proper employment of these addicts, more than they planned. Keywords Relapse, Opioid, Addiction Clinics,Chaharmahal&Bakhtiyari Investigating the Level of Metapsychoplasticity and Behavioral Inhibition/activation Systems of Brain in Patient with Substance Addiction Abbas Alimadadi1, Sima Mazraeh2 1. Faculty Member if University- PhD Clinical Psycgology 2. General Psychology-NDC Background and Aim The term called Plasticity is the specific endowment of nervous system to develop and also to react or adjust to the internal/external environment changes. While, Neuroplasticity refers to changes of neurons or glial cells while the brain develop. neuroplasticity mechanisms are triggered by various natural/artificial stimuli, which may arise in the internal/external environment and they may differ quantitatively/qualitatively. plasticity effects can lead to the Positive/Negative development. which occurs by learning with regard to the cell changes. based some study ,substance addiction is a kind of learning, it has a special plasticity of it down which is negative .Metaplasticity is a level higher than plasticity and also includes the prior synaptic process. The concept of Metapsychoplasticity is consisted of three basic construction sets(Temperament, Attachment style, Defense mechanisms) which of occurs more older than the other psychological phenomena such as personality. the formation type of these construction leads to health or pathology in mental or biological level. It seems that these structures( Metapsychoplasticity)are probably related to brain functions of behavioral inhibition/activation systems, which define affective style and individual behaviors. studying the relation of this factors can be a guide in clinical section especially in the prevention programs. The aim of this study was investigating the level of Metapsychoplasticity and behavioral inhibition/activation systems of brain in patient with substance addiction. Methods 18 male patient with substance addiction participated in research. The control group consisted of 25 normal persons. Short form adult temperament questionnaire(ATQ), adult attachment scale(AA) and defense mechanisms questionnaire(ESQ/40) were used as instrumental research. Results Data analysis showed that the metapsychplasticty elements and behavioral inhibiation/activation systems are significant different between patients and control groups. Patients had insecure attachment, abnormal temperament,Immature defense mechanisem and disturbance in behavioral inhibition/activation systems. Conclusion The concept of metapsycholplasticity refers to the basic formation psychological function which have a main role in health and pathology. It seems that dependency to substance is under the influence of these basic factors and also the result of brain inhibition/ activation systems functions. These issues may refer to the strong correlation between the metapsychoplasticity and neuroplasticity phenomena. The recent finding would have very important positive effects in therapeutic and preventive plans. Keywords Plasticity- Neuroplasticity -Metapsychoplasticity-BISBAS Investigating the Level of Metapsychoplasticity and Behavioral Inhibition/activation Systems of Brain in Patient with Substance Addiction Abbas Alimadadi1, Sima Mazraeh2 1. Faculty Member if University- PhD Clinical Psycgology 2. General Psychology-NDC Background and Aim Introduction: The term called Plasticity is the specific endowment of nervous system to develop and also to react or adjust to the internal/external environment changes. While, Neuroplasticity refers to changes of neurons or glial cells while the brain develop. neuroplasticity mechanisms are triggered by various natural/artificial stimuli, which may arise in the internal/external environment and they may differ quantitatively/qualitatively. plasticity effects can lead to the Positive/Negative development. which occurs by learning with regard to the cell changes. based some study ,substance addiction is a kind of learning, it has a special plasticity of it down which is negative .Metaplasticity is a level higher than plasticity and also includes the prior synaptic process. The concept of Metapsychoplasticity is consisted of three basic construction sets(Temperament, Attachment style, Defense mechanisms) which of occurs more older than the other psychological phenomena such as personality. the formation type of these construction leads to health or pathology in mental or biological level. It seems Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S175 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall that these structures( Metapsychoplasticity)are probably related to brain functions of behavioral inhibition/activation systems, which define affective style and individual behaviors. studying the relation of this factors can be a guide in clinical section especially in the prevention programs. The aim of this study was investigating the level of Metapsychoplasticity and behavioral inhibition/activation systems of brain in patient with substance addiction. Methods 18 male patient with substance addiction participated in research. The control group consisted of 25 normal persons. Short form adult temperament questionnaire(ATQ), adult attachment scale(AA) and defense mechanisms questionnaire(ESQ/40) were used as instrumental research. Results Data analysis showed that the metapsychplasticty elements and behavioral inhibiation/activation systems are significant different between patients and control groups. Patients had insecure attachment, abnormal temperament,Immature defense mechanisem and disturbance in behavioral inhibition/activation systems. Conclusion The concept of metapsycholplasticity refers to the basic formation psychological function which have a main role in health and pathology. It seems that dependency to substance is under the influence of these basic factors and also the result of brain inhibition/ activation systems functions. These issues may refer to the strong correlation between the metapsychoplasticity and neuroplasticity phenomena. The recent finding would have very important positive effects in therapeutic and preventive plans. Keywords Plasticity- Neuroplasticity -Metapsychoplasticity-BISBAS The Relationship between Meta-Cognitive and Cognitive Emotion Regulation with Mental Health in Females Opiate Addicts Farshid Alipoor1, Saber Saeedpoor2 1. University of Kharazmi Tehran 2. University of Kharazmi Tehran Background and Aim Mental Health is affected by many factor this study aimed to investigate the possible relationship between females opiate addicts Meta-cognitive and cognitive emotion regulation with their Mental Health Methods In this descriptive-explanatory study,42 females were selected accessible sampling method .the females completed the Wells Meta-cognitive Beliefs Inventory, Goldbergers General Mental Health Questionnaire and Cognitive Emotion regulation Questionnaire. Results The data analysis showed that there were negative correlations between maladaptive Cognitive Emotion Regulation strategies (Catastrophizing, rumination, self blame and other blame) with mental health .also positive correlation between adaptive Cognitive Emotion Regulation strategies with mental health. And significant positive relationships between meta-cognitive beliefs and general health. In other words, individuals with higher scores in meta-cognitive scale revealed worse general health status. There was also a significant relationship between total scores of both scales and scores on uncontrollability, positive beliefs, cognitive confidence and need to control thoughts. Conclusion Meta-cognitive and adaptive Cognitive Emotion Regulation strategies are effective factors in general health female’s opiate addicts. Keywords Meta-Cognitive, Cognitive Emotion Regulation, Mental Health, Female’s Opiate Addicts The Relationship between Magnitude of Spirituality, Anxiety and Depression in Addict Anonymous and Opiate Dependence Patient under Methadone Maintenance Farshid Alipoor1, Saber Saeedpoor2 1. University of Kharazmi Tehran 2. University of Kharazmi Tehran Background and Aim Aim of the present Study was to determinate relation between Magnitude of Spirituality, Anxiety and Depression in addict anonymous and opiate Dependence Patient under Methadone Maintenance Treatment and also to access the predictability of anxiety and depression from the levels of spiritual in addict anonymous and opiate Dependence Patient under Methadone Maintenance Treatment Methods 42 addicts among addict anonymous and opiate Dependence Patient under MMT Program with sampling accessible selected and answered completed depression, anxiety and stress scales [DASS] as well as Palutzian& Ellison spiritual health Questionnaire Results Revealed that there was a negative relationship between anxiety and spirituality and also negative relationship between Depression and spirituality. The finding revealed addicts anonymous scored higher in spiritual than opiate Dependence Patient under MMT Program also Dependence Patient under MMT Program scored higher in Anxiety and Depression than addicts anonymous Conclusion According to this finding negative relationship between Anxiety and Depression and spirituality in opiates addicts. This can help to choose an appropriate treatment substance abuse S176 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Keywords Results Anxiety, Depression, Spirituality, Opiate Dependence Effectiveness of Detached Mindfulness Techniques in Treating a Craving in Addiction Disorder Farshid Alipoor1, Saber Saeedpoor2 1. University of Kharazmi Tehran 2. University of Kharazmi Tehran Conclusion Results demonstrated the effectiveness of Quality of life therapy On improvement of quality of life of opiate addicts. Keywords Background and Aim The objective of this study was to introduce and explore the effectiveness of detached mindfulness techniques in the treatment of a craving in addiction disorder Methods In a single-subject experimental trial of A-B type, the detached mindfulness techniques were carried out on a subject with craving in addiction disorder. The subject s were assessed at tree stage, A(base line) , stage B(last session) and both month follow-up by Depression Anxiety Stress Scale (DASS-21),General Self Efficacy Scale(GSES),Desires for Drug Questionnaires Franken and Tiffany Heroin Craving Questionnaire. Results After treatment, scores’ patients who received detached mindfulness techniques declined in craving .other finding include score reduction in depression, anxiety and stress score increase in GSES. Conclusion Detached mindfulness techniques were effective in craving in addiction disorder. Keywords Detached Mindfulness Techniques, Craving Effectiveness of Quality of Life Therapy on Improving Quality of Life in Opiate Addicts Jaber Alizadehgoradel1 1.Young Researchers and Elite Club, Ardabil Branch, Islamic Azad University, Ardabil, Iran Quality of Life Therapy, Cognitive-Behavior Therapy, Opiate Addicts Effect of Training on Stress Management Techniques to Reduce Depression in People with Drug-Dependent Jaber Alizadehgoradel1 1. Young Researchers and Elite Club, Ardabil Branch, Islamic Azad University, Ardabil, Iran Background and Aim The main objective of this study is to investigate the effect of training in stress management techniques to reduce depression in people with drug-dependent Methods The tool used in this study is Beck’s depression Inventory. The independent variable of the present study is 8 session treatment to deal with stress performed as a group for the experiment group and the dependent variable which is the score each subject is acquired in Beck’s depression Inventory. The statistical community of this study is male drug addicts living in Mashhad. Subjects were selected randomly and then classified at random into two groups of 15 people of experiment and control groups. In this study, semi-experimental research method and pretest-posttest design with control group was used and data have been analyzed through SPSS software and T test Results The Results of the study showed that stress treatment has been effective in reducing depression of drug users(P<0.005) Conclusion Background and Aim This study was aimed to assess the Effectiveness of Quality of life therapy on Improving Quality of Life in Opiate Addicts. Methods Data analysis revealed that the mean WHOQOL-BREF score in the experimental group had significant higher increase when compared with that of the control group. This was a semi experimental study using control group also pre-test, post-test. Thirty six patients were selected between the entire opiate addicts referred to addiction centers in Ardabil city within judgmental sampling and were randomly assigned into experimental and control groups. They were all administered the WHOQOL-BREF. In experimental group, Quality of life therapy was performed in 8 sessions and the control group was registered in the waiting list for the CB-GT. Therefore, the training program of how to deal with stress plays a main role in reducing drug-addicted users decided to quit and thus help them quit more successful in a longer period of time. Keywords Training to Deal with Stress, Depression, Drug-Dependent Individuals Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S177 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Efficacy of Group Problem-Solving Training and the Effective Communication on Improved Life Quality and Happiness Level in Wives of Addicted People Masoumeh Allahi1, Bahman Akbari2, Behrooz Golchai3, Fatemeh Pourgholi4 1. M.A in Clinical Psychology,Azad University Branch Tonekabone,Iran 2. PhD in Psychology,Azad University Science and Research Branch Guilan,Rasht.Iran 3. Medical Student 4. PhD in Psychology ,Azad University Science and Research Branch Guilan,Rasht.Iran Background and Aim Addiction is among the most unwelcomed social phenomena which has many harmful impacts on families. This work analyzes the effect of group problem-solving training and effective communication on life quality and happiness level in women with addicted husbands. Methods This study is a semi-empirical research with a pretest-posttest design by a control group conducted in centers supported by Social Welfare in Rasht. Among the centers covered by Social Welfare, 5 centers were selected using clustering sampling method. Among 200 wives of the addicted people undergoing the detoxification and rehabilitation phases in these centers, 45 were selected using the sample size formula and divided into two test and control groups. The trials of test group were subject to eight 90 min sessions of group problem-solving training and effective communication, once in a week. To gather required data, life quality questionnaire of world health organization (WHO) and Oxford questionnaire of Happiness were used. Results The findings of present work revealed that group problemsolving training significantly enhances life quality (p = 0.001, F = 33.335) and happiness level (p = 0.001, F = 16.620) of the wives of addicted people. Besides, the effective communication group training improves significantly the life quality (p = 000, F = 79.954) and happiness level (F = 10.880, p = 0.003) of these women. Moreover, the findings show noticeable improvement of physical health and social communications among the women. Conclusion The Results of this work indicate that by offering a long-term plan for group problem-solving training and the effective communicationto the wives of addicted people or intervention in their families it is possible to improve the mutual communications between them and solve their problems and improve their life quality and happiness level. Keywords Wives of Addicted husbands, Problem-Solving, Effective Communication Assessment of Parent-Child’s Relationship Quality Among Addicted and Non-Addicted Adolescent Omid Amani1, Saeed Ghodrti2, Sana Peykani3 1. Shahid Beheshti 2. Shahid Beheshti 3. Shahid Beheshti Background and Aim Nowadays addiction is a global issue that kills thousands of people annually and one of the groups which are more vulnerable to this social and mental problem are adolescents. This research conducted to assess the quality of parent-child relationship among addicted and non-addicted adolescents. Methods To conduct this research, 34 adolescents who were clients of Qazvin addiction treatment centers and they were between 14-18 years old were chosen for this purpose by the use of convenience sampling method, Also 34 non-addicted adolescent were chosen from high school level and those adolescents were paired by their age, gender and educational level who answered the quality of parent-child relationship questionnaire. In order to do statistics analyses, independent sample t-test was used. Results The Results of this research showed that the quality of motherchild relationship and all of its component (positive affect, communication, role confusion, replication ) in non-addicted adolescents were meaningfully better than addicted adolescent. Also the quality of father-child relationship and its subscales (positive affect, communication, anger and father involvement) were meaningfully better in non-addicted adolescents than addicted adolescents. Conclusion The quality of parent-child relationship in addicted adolescents is worse than non-addicted adolescents. Keywords Parent-Child’s Relationship.Adolescent .Addicted Assessment of The Relationship between Spiritual Intelligence and Sensation Seeking among Drug Addiction Omid Amani1, Saeed Ghodrti2, Sana Peykani3 1. Shahid Beheshti 2. Shahid Beheshti 3. Shahid Beheshti Background and Aim Nowadays, drugs addiction is one of the important problem and prominent social deviance in human life which can harm sociocultural base of every country and will afflicted by problems caused by abusing the drugs has some negative impacts in the wellbeing of members of nations. This research has been conducted to assess the relationship between spiritual intelligence and affectivity among drug addictins. S178 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Methods The sample consists of 132 addicted persons which has been sampled with convenience sampling method from the private and governmental clinics of Qazvin city. The questionnaires which has been used for this purpose was the self-report questionnaire of spiritual intelligence and Zukerman’s affectivity scale (zukerman, 1980). Results Data analysis by using the step by step regression and correlation coefficient showed that there is a negative meaningful correlation between the spiritual intelligence and the sensation seeking among the drug users (p<0.5). In other words, the affectivity scores decreased with increasing in the spiritual intelligence scores. Also the sensation seeking components had negative relationship with addiction scores. Conclusion By this research we can conclude that people with low levels of spiritual intelligence are so prone to addiction and will do more risky jobs. Keywords The Results showed the first book covers more theories of social control and labeling and the second book contains the theories of cultural transmission, whereas the third book more encompasses the theory of anomie. Altogether Anomaly theory, Merton isolation theory, Labeling Theory and Cultural transmission theory had the highest frequency and Social control theory and theory of social development model had the lowest frequency in the texts Conclusion In high school social science courses, the subject which directly relates to the problem of addiction or social deviance does not exist. The discussion of addiction in the education system of Iran has not been considered as serious and it is still not considered to as a phenomenon. But statistics indicates increasing the addiction among the youth. Alongside the media, the formal education system, are considered an important means to inform people that can discuss ways to prevent of addiction. Although the high school is not a good epoch to education of the dangers of addiction, but the consequences of some risky behaviors can be considered in this texts. Keywords Spiritual Intelligence.Sensation Seeking. Drug Addiction The Survey of Components to Preventing Addiction in High School Sociology Textbooks Osman Amini1, Jafar Ahmadi2, Mohammad Adib Hesami3 1. MA in Knowledge and Information Science, Urmia University of Medical Sciences, Boukan Nursing Faculty 2. MA in Cultural Studies, Urmia Municipality 3. MA in Nursing, Urmia University of Medical Sciences, Boukan Nursing Faculty Background and Aim The textbooks are critical resource for education of prevention of addiction. For this reason, its inclusion in textbooks is useful to understand addiction in teenager. This paper aims to survey the components of addiction in educational textbooks. For this purpose, we used the theories of addiction. The most popular theories are Anomaly theory, Merton Isolation theory, Labeling Theory, Cultural Transmission theory, Social Control theory, Theory of social development model. In this paper we intend to realize the theories are reflected in the texts. Methods Results The High School Textbooks of Humanities include three books entitled “Sociology 1, Sociology 2, Sociology New World Order” which are taught in this course. The first book contains three chapters that have 18 lessons. The second book involves three chapters and 14 lessons and thirds contain 4 chapters and 14 lessons. The quantitative content analysis method was used for analysis the textbooks. This means that each course in terms of content is analyzed to determine the courses which cover the theories of addiction prevention. For the analysis of texts, each theory was divided into categories and the text contents were adapted in categories Addiction, Textbooks, High School Sociology, Theories of Addiction Investigation of Reproductive Health Condition of Women Gone to the Selected Drug Detoxification Centers Sediigheh Amir Ali Akbari1, M Bahri Khomami2, H Alavi Majd3 1. Faculty of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran. 2. Faculty of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran. 3. Professor, Dept. of Biostatistics, Faculty of Paramedical, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Background and Aim Scientific evidences show that drug abuse and addiction create different challenges for women compared to men; therefore, the current research has been carried out in order to Survey study of reproductive health condition of women referred to the selected drug detoxification centers in Tehran, Iran. Methods The present study has been conducted by means of descriptive method with the sample size of 200 women referred to the selected drug detoxification centers in Tehran. Materials of study were questionnaires containing questions about demographic information, status of drugs being used, and general health by the General Health Questionnaire (GHQ), obstetrics, cyclic period, family planning history and menopause status. SPSS-16 software was applied to analyze the data collected. Results Opium and crack, in the priority, were the most prevalent drugs used and the most common age of the consumption onset was 14 to 20 (34%). General health status was undesirable in 46.5% of Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S179 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall women. 27/6% of pregnancies led to the birth of LBW infants. After getting addicted, women reported a change in the amount of menstrual bleeding (45.5%).Women having sexual intercourses have applied one of contraceptive methods, the most common of which was the withdrawal method. The average age of menopause was 40.18 ± 8.03 years old and 47.3% had desirable quality of life among the menopause ones and 7.3 %of them suffered from cancer. Conclusion Based on the Results of this research, it is concluded that the reproductive health conditions of women who are addicts or drugs/ substances abusers requires more study and supervision. Keywords Reproductive Health, Women, Addiction Compare the General health Status of Socially Harmed and No Socially Harmed Women in Tehran Sediigheh Amir ali akbari1, Gohar Mohammadi2 1. Dept. of Midwifery, Faculty of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran. 2. Dept. of Midwifery, Faculty of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Background and Aim With regard to the problem due to harmed- women in societies, due consequences and the importance of women health, this study was carried out to comparison general health between the Socially Harmed and No socially Harmed Women in Tehran. Methods This analytical research was conducted on 75 socially harmed women who were clients of harm reduction centers, and 170 non-socially harmed women in the city of Tehran. socially harmed was defined based on the two main components violence,addiction,Data collection tools included questionnaires of general health status(GHQ), and social harm assessment. The data collection method was structured interviews. All women were interviewed as an organized construction method. Gathered data analyzed as descriptive (frequency, mean and percentile) and Analytic(x2) statistic methods by spss18. Results Results showed that the mean of the women age was 34.27±9.6 in case group and 34.05 ±7.9 in control group.24% of women with and 100% without social harmed were married . Considering general health there was a significant statistical difference between the two groups (p<0.001) – 89.3% of the socially harmed women suffered from inadequate general health. Conclusion As result, social harmed had significant impacts on women general health status and it is necessary to have a special program in health system for supporting women in purpose of preventing of physical and emotional problems. Keywords Social Harmed Women, General Health, Women Drug Abuse Background and Mental Health Status of a Sample of Methadone/ Buprenorphine Maintenance Patients in Iran Pegah Amiri1, S. Momtazi, N. Musavinasab2, B. Daneshvar, A. Moradi3, I. Omidi4 1. State welfare organization of Iran, East Azerbaijan, Marand 2. Zanjan University of Medical Sciences and Substance Abuse Prevention and Treatment Office, Iran 3. Agonsit Treatment Center, Iran 4. Private Researcher, Canada Background and Aim Methadone and buprenorphine maintenance treatment is an approved drug policy in Iran. There are numerous maintenance treatment centers using one of these drugs run by public and private sectors. In this study, we aimed to find out about the mental health status of patients under treatment in these centers. Methods We assessed 150 patients under treatment with methadone or buprenorphine maintenance in different centers in Tehran and two other cities—Zanjan and Karaj. We built a questionnaire including drug use history and demographic features. For assessment of patients’ mental health, we used General Health Questionnaire–28 (GHQ). SPSS version 16 software was used for data analysis. Results Our sample was 150 male patients, including 108 people on methadone and 42 on buprenorphine. The age range was between 21 and 55 with mean age±standard deviation of 32.2±8.21 years. In all, 102 people were married, and 48 (32%) were single or divorced. Duration of drug use before entering treatment was 0.25 to 20.00 years with a mean of 6.37 years and mean age of first drug use of 22.6±7.36 years. Seventy-three people (48%) had a history of injecting drugs at least two times. Duration of drug injection before treatment for this group was 0.15 to 4.0 years with a mean duration of 1.88 years. Age of first drug injection was 25.9±8.36 years. Nine people (6%) had a history of needle sharing. All patients had a diagnosis of opioid dependence according to DSM-IV-TR criteria. The most frequent opioid used was opium, which was the main drug in 123 patients (82%). Heroin was used by 104 (69%). Thirty-three persons (22%) also had a history of crystal methamphetamine abuse. With a cut-off point of 6 or more, GHQ showed that 28 percent of the patients had mental health problems. In GHQ subscales, social dysfunction was the most frequent problem (38%), while depression was the least frequent problem (20%); anxiety and insomnia were present in 32 percent, and somatic symptoms were present in 24 percent. Nonparametric analysis and the Mann-Whitney test—used to analyze data without normal distribution—showed that the GHQ-28 score of people who used heroin or opium as the main drug was not significantly different, but those patients who also had a history of crystal methamphetamine abuse showed significantly more mental health problems, with a mean GHQ score of 9.0 and a median equal to 8.0, compared with those who did not use methamphet- S180 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall amine, with a mean score of 4.4 and a median of 2.0 (p<0.005). There was no considerable difference between methadone and buprenorphine groups regarding their drug use behavior or mental health, and there was no significant difference between opium and heroin abusers regarding their GHQ score. Conclusion Mental health problems are frequent in methadone maintenance and buprenorphine maintenance treatment patients. The most frequent problem is social dysfunction. History of methamphetamine abuse was associated with more mental health problems. Keywords Methadone,Buprenorphine,Drug,Abuse 3 4 Borzoo Amirpour1, Mehran Farhadi2, Maryam Hashemi3 1. Psychology Department, Payame Noor University 2. Department of Psychology, Faculty of Economics and Social Sciences, Bu-ali Sina Universitiy, Hamadan, Iran 3. Department of Psychology, Faculty of Economics and Social Sciences, Bu-ali Sina Universitiy, Hamadan, Iran Methods 5 Background and Aim Internet addiction in the diagnostic and statistical manual of mental disorder, 5th edition (DSM-5) specifically, has been investigated and it is characterized as poorly controlled internet use, so can lead to impulse-control disorders. This study was conducted to Comparison of impulsivity and its dimensions among high-school female students with and without internet addiction disorder. Methods This descriptive-comparative causal study was performed on 200 high-school female students were selected from Kangavar city, Participants were chosen by Single-stage cluster sampling. Subjects completed two scales impulsiveness scale (Barratt et al, 1995) and internet addiction test (Young, 1988). Data were analyzed and processed using descriptive statistics and T test, by SPSS18. Results result revealed that Overall, 17 out of the 200 students identified with internet addiction that they obtained significantly higher scores on impulsivity in addition, among the three dimensions of impulsivity(non-planning impulsiveness, motor impulsiveness and cognitive impulsiveness) in cognitive impulsiveness students with internet addiction obtained significantly higher scores. Conclusion The Relation between Attending at Narcotics Anonymous (NA) Groups, and Mental Illness and Health in Addicts Addiction is a disease that has many bio-psycho-social consequences, and its treatment programs have different outcomes. This study investigated the relationship between attending at Narcotics Anonymous programs, with mental health and illness in addicts. Borzoo Amirpour , Rahim Goli , Abedin Darabi , Naser Veysi , Zinab Ahmadi , Neda Isfandiyari6 1. Payam e Noor university 2. Kermanshah University of Applied Science and Technology 3. Payam e Noor University 4. Payam e Noor University 5. Kermanshah University of Applied Science and Technology 6. Payam e Noor University 2 Internet Addiction Disorder, Impulsiveness, Student Background and Aim Comparison of Impulsivity and Its Dimensions among High-School Female Students with and without Internet Addiction Disorder 1 Keywords This study like, numerous studies showed associations between Internet addiction and mental health problems, So with regard to Internet access in multiple setting such as home, school, Parents and teachers is essential to monitor the Internet use rate. A sample of 110 subjects (55 subjects in each group) of male anonymous addicts in Isfahan was selected. Ninety-item checklist of the mental health, mental well-being questionnaire, and self-esteem questionnaire were performed in the two groups (one group participated at the program for six months or less, and another group for a year and a half or more. Data were analyzed with independent t-test and Pearson correlation methods. Results indicated that participation in Narcotics Anonymous programs were associated with reducing mental problems and increased mental health. Furthermore, mental health and mental illness dimensions were correlated in addicts. Conclusion Addiction creates problems such as work, financial, physical, social, and psychological problems. Therefore, multi-faceted Narcotics Anonymous programs can reduce drug addiction and increase mental health. Keywords Narcotics Anonymous, Mental Illness, Mental Health. Effectiveness of Gratitude Training on Psychological Burden and Quality of Life Among The Wives of Male Addicted Patients in Shahreza City Hamidreza Andalib1, Gholamreza Manshaee2 1. MA Student of Psychology, Esfahan Science and Research Branch, Islamic Azad University,Esfahan, Iran. 2. Assistant Professor, Department of Psychology, Esfahan Science and Research Branch, Islamic Azad University, Esfahan, Iran Background and Aim This study aimed at investigating the effect of teaching gratitude on the decrease of the psychological burden of spouses and Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S181 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall improvement of the matrimonial life quality of those who have requested for help in order to abandon their addiction. Methods The applied method in the present study was semi-experimental in which both pre-test and post-test were conducted and two experimental and control group were investigated. To this end, 30 spouses were selected randomly as participants, 15 of which were identified as experimental group and other 15 as control group. The experimental group experienced 9 sessions of treatment to learn how to show their gratitude. The instruments used in this study consisted of the psychological burden questionnaire of Zarit and et all (1980) and matrimonial life quality questionnaire of World Sanitary Organization (1996). The data were analyzed by multi-variances statistical methods of covariate analysis and variance analysis Results Based on the revealed Results, detected F in showed a significant difference between the post-test averages scores of experimental and control group for psychological burden and matrimonial life quality Conclusion Results Findings showed that 80% of the sample had personality disorders, %56/7 of them had more than one disorder, % 23/3 had only one disorder, and no schizotypal personality disorder was presented in the subjects. Passive - aggressive Personality disorder and depression were seen more than other disorders. Among coping strategies, somatization (%10), cognitive assessment (%3/3), social support (%3/3), problem-solving (%6/7), and coping method of emotion-centered) %76/7) were used. Conclusion Considering the high prevalence of personality disorders in this population, and dealing with life events and difficulties with emotional manipulation of emotion-centered strategies used by them, teaching life skills and problem solving skills are recommended for this group. Keywords Drug Abuser Women, Personality Disorders, Coping Strategies Comparison of Methods for Problem Solving and Religious Orientation of the Individuals Abuse Substances and Normal Bushehr Based on the findings of this research teaching gratitude has been suggested an effective method for promoting quality of life and decreaseing of Psychological Burden in Wives of Male Addicted Patients. Keywords Teaching of Gratitude, Psychological Burden, Spouses, Matrimonial Life Quality, Addiction The Study of Personality Disorders and Coping Strategies in Drug Abuser Women Sara Ansari1, Banafsheh Ghoraei2, Parvin Afsar-Kazerouni3, Mozhgan Patoo4 1. Shiraz University of Medical Sciences, Department of Mental Health 2. Assistan Prof. of Tehran University of Medical Sciences, Mental Health Resrarch Centre, Tehran Psychiatric Institute 3. PhD. in Social Medicine, Center for Disease Control, Shiraz University of Medical Science 4. PhD student in psychology, TarbiatModares University Background and Aim Today women are more than before drugs abuse and affected by its consequences. Drug abusers women than men are experienced severe physical and mental problems. The present study aims to assess personality disorders and coping strategies in drug abuser women in Shiraz Methods This research study is ex post facto (cross sectional - descriptive) sectional.30 women used drugs were selected by accessible sampling. All subjects were evaluated and compared by Moss and Billings’ Coping Style Questionnaire and the Structured Interview of DSM-IV disorders (SCID-II). Data were analyzed by using descriptive statistics. Mojtaba Ansari1, Maryam Farhadi2, Adibeh Tammari3 1. Social Security Organization 2. Education and Training Organization 3. Free Background and Aim This study aimed was to compare methods of problem solving and religious orientation of the Individuals abuse substances and normal Bushehr. Methods This study was a comparison, the research sample of 160 selected sampling and questionnaire methods of problem solving and religious orientation responded. Results Data analysis using multivariate analysis of variance showed that inhibition of the problem Individuals abuse substances is significantly lower than normal. Between Individuals abuse substances and normal of religious orientation and its dimensions are significantly different. Conclusion Substance abusers of religious orientation and problem solving methods are faced with problems that could be causing substance. Keywords Problem Solving, Religious Orientation, Individuals Abuse Substances Tendency to Addiction Causes of Women in the Cty of Shahreza Keyvan Arabi1 1. Master of Clinical Psychology, Islamic Azad University of Tonekaboon,MaZa S182 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall ndaran,Iran,Welfare Employee of City Shahreza, Consultant and Clinical Psychologist for Chronic Psychiatric Patients Background and Aim The present study the causes of the trend of women in the township shahreza addiction.In the same context, the present study aims to investigate the causes of the tendency to abuse of women in the social dimension, economic, emotional sexual behavior, and later. Methods The study of the kind of descriptive survey.Therefore all treatment centers and counseling in the city operated a list was prepared by randomly (sampling cluster), a center of the center samples consisted of 100 women who turn to It had been selected as age, sex, drug and education have been controlled in this study. All subjects completed the test questions tend to cause addiction in the social, economic, emotional, sexual, behavioral Cronbach 923/0 responded. The data obtained were analyzed using spss software. Results Results indicate that Atyadznan trends in social, economic, emotional, and sexual behavior at ? <0/01 was approved. Conclusion The Results indicate that it is all the dimensions of the tendency to drug addiction among women in the social dimension, economic, and then, emotional sexual behavior can and cannot be drug addiction to explain the next one.It can also be concluded that are related to the social dimension and emotional later. - the needs of the emotional and social needs of the most important causes a tendency to addiction in women and the lowest many due to the sexual dimension. Keywords Addiction Women,social Dimension,economic Dimension,Emotional Dimension,Sexual Dimension Comparing the Effectiveness of Cognitive-Behavioral Therapy(CBT) on Violence Rate and Life Quality of Addicted Prisoners in Rasht City keyvan Arabi1 1. Master of Clinical Psychology, Islamic Azad University of Tonekaboon,MAz andaran,Iran,Welfare Employee of City Shahreza, Consultant and Clinical Psychologist for Chronic Psychiatric Patients Background and Aim Present research was executed aiming to study the effectiveness of cognitive – behavioral therapy on decreasing violence and increasing life quality of Rasht’s city prisoners.Therefore, the aim of this study 1. Examine the impact of education, cognitive - behavioral (CBT) on aggression among prisoners was a drug addict. Methods The sample society of present research is 350 client of social service in Rasht city prison.40 of individual who their score in violence questionnaire was higher than cut edge and lower than normal in quality of life questionnaire were chosen by random sampling method after scanning and replaced in two test and control groups. The test group received 12 sessions of 45 minutes each session cognitive – behavioral therapy and the control group received no education. The each group answered the questionnaires once again and Results were analyzed by covariance analyze method. Results Analyzes Results indicate that in a synthetic variance, cognitive – behavioral therapy is effective on decreasing violence and increasing quality of life and also in decreasing prisoners’ violence (P<0/0001). But it had no meaningful effect on increasing prisoners’ quality of life (P>0/0001). Conclusion Based on Results obtained in this research the cognitive-behavioral therapy could be a proper method to decrease violence. Keywords Cognitive-Educational Education, Violence, Life Quality The Effectiveness of Music Therapy Methods and Token Economy of Scale Aggression, Drug Addicts Leaving the Camps Isfahan Keyvan Arabi1 1. Master of Clinical Psychology, Islamic Azad University of Tonekaboon,MAz andaran,Iran,Welfare Employee of City Shahreza, Consultant and Clinical Psychologist for Chronic Psychiatric Patients Background and Aim The present study investigated the efficacy of music therapy methods and token economy of scale aggression, drug are leaving camps in Isfahan. Therefore, the objectives of this study: 1. Examine the effects of music therapy on aggression 2. token Economic Effects on Aggression 3. Compare these two approaches is the extent to which aggressive treatment approach was more effective in reducing aggression addicts are leaving. Methods The study sample included 200 addicts had left the camps Isfahan are among the people after the test run aggression in 30 patients who score in aggression over 45 achieved using random sampling in three groups: control and 10 who were assigned to collect data from the aggression Questionnaire (AGQ) was used. program of music therapy in 6 sessions of 90 minutes in the first trial, week 2 sessions as well as strengthening the token economy 6 sessions of 90 minutes in the second group experimental sessions took 2 weeks and the control group were managed without any training and after training, post-test was administered to all three groups. The Results obtained with the use of one-way analysis of covariance (ANCOVA) was performed. In addition to determining the difference between the means of the Bonferroni method was used. Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S183 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Results The Results showed that the two methods of music therapy and token economy on reducing aggression among addicts leaving has been significant.and (F(2,26)=41/851 ، P=0/000 ،ETA=0/763) Conclusion Thus it can be concluded that music therapy methods and token economy are leaving the drug is effective in reducing aggression was defined as the difference between the average using the Bonferroni method token economy (12/538) is greater than the average effect of music therapy methods reduction in aggressive addicts. Keywords Music Therapy Methods, The methods Token Economy, Aggressive, Drug Addicts Leaving Compare the Effectiveness of the Two Education Cognitive Group - and the Analysis of Mutual Treatment Centres on the Happiness Drug Addicts Improved Over the Feet of the County Shahreza. Keyvan Arabi1 1. Master of Clinical Psychology, Islamic Azad University of Tonekaboon, Mazandaran,Iran,Welfare Employee of City Shahreza, Consultant and Clinical Psychologist for Chronic Psychiatric Patients Background and Aim This subject, study comparing the effectivenss of the training group cognitive – behavioral and analyzing the research 1.Effect of training cognitive –behavior happiness. 2. Effect of education analyzing the behavior of mutual on general health and happiness.3. Comparing the tow educational methods on happiness is ,and which educational methods are more effective on the happiness improved drug addicts. Methods There fore community study 500 drug addicts improved over the feet of the city centres shahreza. 200 improved drug addicts responded to questionnaires and 70 people from the Oxford Happiness Questionnaire score was below 42 had won 36 randomly selected individuals and groups open to the crash test and control group were replaced . subjects in experimental groups trained seven sessions of cognitive – behavioral analysis and interaction behaviors were studied . All subject again responded to the questionnaire . Data obtained with covarians analysis were analyzied . Results The finding showed that educational method cognitive – behavioral and analyzing of mutual happiness was effective and the first hypothesis was confirmed . Conclusion Keywords Cognitive – Behavior, Behavior Analysis of Interaction, Happiness, Improved Drug Addicts Compare the Effectiveness of the Two Education Cognitive Group - and Mutual Behaviour on Public Health Centres of Drug Addicts Improved Over the Reet of the County Shahreza. Keyvan Arabi1 1. Master of Clinical Psychology, Islamic Azad University of Tonekaboon, Mazandaran,Iran,Welfare Employee of City Shahreza, Consultant and Clinical Psychologist for Chronic Psychiatric Patients Background and Aim This subject, study comparing the effectivenss of the training group cognitive – behavioral and analyzing the research 1.Effect of training cognitive –behavior on general health and. 2. Effect of education analyzing the behavior of mutual on general health.3. Comparing the tow educational methods on general health is ,and which educational methods are more effective on general health improved drug addicts. Methods There fore community study 500 drug addicts improved over the feet of the city centres shahreza. 200 improved drug addicts responded to questionnaires and 70 people from the general health questionnaire score above 22 had won 36 randomly selected individuals and groups open to the crash test and control group were replaced . subjects in experimental groups trained seven sessions of cognitive – behavioral analysis and interaction behaviors were studied . All subject again responded to the questionnaire . Data obtained with covarians analysis were analyzied . Results The finding showed that educational method cognitive – behavioral on general health has been instrumental in the out come of the second hypothesis was confirmed by tow methods and the educational component of anxiety and social dysfunction but was effective on depression and physical symptoms have been ineffective . But generally the two methods statistically , none of the dependent Variables was not statistically different . Conclusion There fore ,it con be concluded that training cognitive – behavior and analyzing the behavior of both the increasing interaction of general health of improved drug addicts and con be effective of these methods to increase these components con be used. Keywords Cognitive – Behavior, Behavior Analysis of Interaction, General Health, Improved Drug Addicts There fore ,it con be concluded that training cognitive – behavior and analyzing the behavior of both the increasing interaction of happiness of improved drug addicts and con be effective of these methods to increase these components con be used. S184 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Prioritize of Fears Improved Drug Addicts and their Coping Behavior. Keyvan Arabi1 1. Master of Clinical Psychology, Islamic Azad University of Tonekaboon, Mazandaran,Iran,Welfare Employee of City Shahreza, Consultant and Clinical Psychologist for Chronic Psychiatric Patients Background and Aim Drug addicts who have left are in a position to encounter all kinds of fears and tensions, and make decisions about what to do when confronting the person in need of his judgment. We aim to prioritize their fears addicts improve their coping behaviors were investigated. Methods 430 addict improved (25 to 35 years) men and women available Isfahan participated in this survey. Questionnaires, personal and family information, his fears after drug withdrawal, stress and severity of their exposure, and examine ways to improve the treatment of religious beliefs filled and methods of descriptive statistics ranks of percent and Order priorities have been us. Results The Results showed that the majority of drug addicts have improved in the first priority of the pain caused by the body of the Withdrawal of the drug fear of special to stress the greatest fear of (hangover and lassitude ). Conclusion The most common fear among addicts improved The Hangover again fear And then the fear of craving and desire. Most oppose them, using the experience of the coaches, knowing and talking about a situation they are in and saying Prayers . Keywords Fears of the After Leaving the Drugs, Hangover and Lassitude, Improved Drug Addicts, Coping Behavior The Effectiveness of Group Metacognitive Therapy on Dysfunctional Attitudes in Addicted MenTreating with Methadone Hamzeh Arbab1, Maliheh Rahmani2, Hassan Zarei Mahmoodabadi3 1. MA of Counseling, Kashan University of Medical Sciences 2. Postgraduate Student of Clinical Psychology, Kashan University of Medical Sciences, Student Research Committee 3. Assistant Proffessor in Counseling, Yazd University Background and Aim Nowadays, there are many psychological factors in field of addiction treatment that especially effect oneffectiveness of pharmacotherapy alone in a long time. In most cases their effects on outcomes, are unknown.Even despiteunderstanding these factors, appropriate psychological interventions have been less for control of these.The goal of this study is“the effectiveness of group metacognitive therapy on dysfunctional attitudes in addicted mentreating with methadone. Methods Measurement: Dysfunctional Attitudes Scale (DAS) (beak and Weissman, 1978) (α=0/89), metacognitive therapy (MCT) protocol (Adrian Wells, 1999). Sample: 24 addicted men (M=35/33 & SD= 2/35) that was treating by methadone in Kashan’sOmid methadone therapy institute. Samples were dividedtwo groupsrandomly. Two groups were randomly assigned to experimental group and control group. Method wasquasi-experimental with pre-test and post-testusing cloning and taking entrance criteria. Results Results show a significant different betweenexperimental and control group.Experimental grouptook significant reduce in posttest in DAS. This finding is consistent with most previous studies in this field. Conclusion Thus, MCT can be effective in a short treatment. We consequence that group metacognitive therapy is effective to moderatedysfunctional attitudes and negative emotions and affects (anxiety, depression and…).Thus this method can Strength addicted men in front of most important stimulates encouraging substance dependence. Moreover MCT help addicted men to promote their meta-beliefs about thought and affects. In this method participants were educatedsome techniques like mindfulness, InsteadChallenge with contents of cognitions.Finally an adaptive thought style develops by dropping mind ruminations and reducing maladaptive self-monitoring. Our findings are supported by several researches. Keywords Metacognitive Therapy, Dysfunctional Attitudes, MethadoneMaintenance Therapy Comparison between the Amount of life Skills among Patients Men (With Drug Abuse or Drug Dependence) and Healthy Men In the Area of Arasbaran in 1393 Batool Arhami Khage1, Kolsom Arhami Khage2, Uagob Kamrani3 1. Province of Azerbaijan Shargy– City of Harris – City of Khwaja -Street of Behzisti - Office Behzisti Khwaja 2. Province of Azerbaijan Shargy– City of Harris – City of Khwaja -Street of Behzisti - Office Behzisti Khwaja 3. Province of Azerbaijan Shargy– City of Harris – City of Khwaja -Street of Behzisti - Office Behzisti Khwaja Background and Aim Today, drug addiction and drug abuse become as a social problem and mental different country and that are threatens highly different countries and societies. According to the World Health Organization in 2004 ؛life skills can be used also as a strategy for improving mental health and also as a tool in the prevention of social damages like addiction and .... The aim of this study is Comparison between the amount of life skills among patients men ( With drug abuse or drug dependence) and healthy men In the area of Arasbaran in 1393 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S185 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Methods Research Methods This study is descriptive. The population of this study is including all men over 20 years In the area of Arasbaran. Arasbaran including the counties of Harris, Ahar,khodafain, Varzeqan and kaleubar of province of Azerbaijan shargi. There were 155 patients men (ReferredWithdrawal and addiction treatment centers.and medium-term residence (Kamp) under behzisti or medical university located in Arsbaran) and 155 healthy men who were randomly selected. Measuring instrument is questionnaire of life skills with 144-item . All participants have responded to the questionnaire And for to analyze the data obtained from the questionnaire were used of methods independent t, and the Results were analyzed using spss software. Results The Results obtained show that there were significant differences in the means of patients men ( With drug abuse or drug dependence) and healthy men in the variable life skills. (p <0/05) Conclusion Healthy men have higher levels of life skills compared with men patients ( With drug abuse or drug dependence) These skills may be effective in prevent of their tendency to drug abuse or dependence. And accordingly is suggested to prevent The tendency of individuals to drug abuse or dependence are trying to improve their life skills. Keywords Life Skills. Drug Abuse . Drug Dependence Preventive Methods in Addictionof Specific Groups (Adolescents and Young adults) Mohammad Ariana1, Heydar Khenari2 1. Psychological and Counseling Center 2. Psychological and Counseling Center Background and Aim Addiction Prevention in the Youth: Nowadays, drug addiction is a mental, social and health problem in the world. In the last few decades,addiction to legal and illegal drugs has been widespreadand suggested the emergence of a serious problem in terms of physical, mental and social health. From a sociological and psychological perspective,one of causes of people’s tendency of individuals to narcotics is the psychological rediness and behavioral disorders in the youth such as mental pressures,thinking problems,anxiety, failures,and so on.That’s why they tend tonarcotics to get relieved and of the pressure,which is an astray. Methods The primary preventive methods are applied to decrease emotional demonstration in the society through combating the stressors and other moders.ods which potentially cause mental disorders. Secondary preventive methods are the programs which are meant to decrease (lower) the mental disorders by holding low and, or intermediate disorders.This method is applied in early diagnosis and quick treatment. Level three preventive methods are the programs applied to decrease the effects of early and, or late complications in mental illnesses. The purpose of these programs is to restore the total social role of the individual in the shortest possible time. Results Strategies and Suggestions: - With an emphasis on the primary preventions method, the most basic way in prevention is to teach adolescents life skills, in other words, making them able to resist against life difficulties.The researchers have been able to run various courses and workshops in Qaemshahr based on CBO plans under the supervision of Behzisti organization, and have achieved some objectives in this regard. There are indexes showing this claim. - The most effective way in making people (adolescents) aware, is setting up homogeneous group meetings (workshops) and monitoring discussion about a topic. - Deciding on the topics to be discussed with adolescents in small groups. - Deciding the necessary contents to be discussed with parents. - - The influence of popular figures (charactors) in any region and neighborhood to help prevent drug abuse in adolescents. Conclusion Addiction Prevention in the Youth: Nowadays, drug addiction is a mental, social and health problem in the world. In the last few decades,addiction to legal and illegal drugs has been widespreadand suggested the emergence of a serious problem in terms of physical, mental and social health. From a sociological and psychological perspective,one of causes of people’s tendency of individuals to narcotics is the psychological rediness and behavioral disorders in the youth such as mental pressures,thinking problems,anxiety, failures,and so on.That’s why they tend tonarcotics to get relieved and of the pressure,which is an astray. Some misinformation of the youths on addiction: - Trying narcotics once does not cause addiction. - Using drugs is useful when one is working at night and, or doing extra work for example indrivers and students. -Addiction does not affect all negatively in physical, social and economic aspects. - Narcotics are offered always by criminals. Adolescence needs: Physiologic,Affective,Sexual, Cognitive,Social,Reccognitional,Spritual needs. Adolescencedevelopments: 1- Physical. 2- Cognitive: Failure in understanding other people’s emotions, Difficulty logical thinking,Wishful thinking. 3- Affective: Emotion intensity,Hormone release increase,Sense of independence,Failure in understandingParents. Adolescence psychological features: Hastiness,Narcissism,Rapid decision making,Sense of competition,Valuation,Passionate friendship,Pessimism to life,Sense of criticism,Sense of adventures. Keywords Addiction - Youth - Prevention The Comparison of Personality Characterstics between Dependence Adult with Normaladult (Not Dependence) S186 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 Nasim Arjhang1 1. Azad University.Tehran.Rodehan.Iran The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Background and Aim Introduction:The purpose of the current study was,comparison of personality characterstics between dependence adult with normaladult. Methods The method of present study was Ex-post(after the occurrence),is a researcher looking to discover and explore the relationship between personality characteristics and the phenomenon of drug addiction.Thesampels were 60 persons included boy adults between 15-20 ages.30 persons of ordinary and 30 people arrested for drug addicts in the prison of Isfahan province statistical society ,people are examples of simple random sampling took place. the tools used to create personality questionnaire form has been the 370 of Minnesota. In order to analyze the data from the t-test was used in 99% confidence level. Results Findings: the Results indicated a significant difference between the two groups in the means community characteristics, depression, paranoia, personality features of a patient’s own, mental fatigue, hysteria, schizophrenia and scaleL (lie detector) ﻭf (mental disturbances) with 99% there is a significant difference. and more than of the addicted teens were normal, but in Hypomanya and scale properties of the k (the defensive aspect) significant differences were observed between the two groups. Conclusion Conclusion The Results of this research and the specific characteristics of thedrug is approved.These features and characteristics can be used as factors underlie and sustain an addiction or drug addiction has been exacerbated by the formation and and it is better to treat drug addicts not only body characteristics but also to the characteristics of attention is also paid to the personality problems. Keywords Drugs, Personality Characteristics,Addiction Relationship between Loneliness, Excitement Seeking and Drug Industrial betwen Addicted Youth Nasim Arjhang1 1. Azad University.Tehran.Rodehan.Iran Background and Aim The aim of this research was relationship loneliness, excitement seeking and drug addiction among young people between the ages of 20-30 industrial centers addiction . Methods This descriptive correlation study that aims to explore the relationships between variable. Samples included 150 people addicted to drugs addiction Mkhdrsnty center of Isfahan city that is randomly selected. Instruments used, Loneliness Scale (UCLA), sensation seeking scale Arendt (AISS) is. Mnzvrtjzyh analyzing the data, the correlation coefficient r and regression analysis were used. Results The Results showed a significant relationship between sensation seeking and drug addiction, drug addiction industrial industrial Loneliness is confirmed. Conclusion Two variables predicted loneliness and sensation seeking drug industry have made a significant variable, but between these variables based on stepwise regression method, the best predictor for loneliness, drug addiction industrial be. Keywords Loneliness, Excitement Seeking; Drug Industry Evaluation of Smoking Pattern and Its Correlation with Addiction among Substance Abusers Mahshid Aryanpur1, Zahra hessami2, Homan Sharifi3, Gholamreza heidary4 1. Tobacco Prevention and Control Research Center, National Research Institute of Tuberculosis and Lung Disease, Shahid Beheshti University of Medical Sciences 2. Tobacco Prevention and Control Research Center, National Research Institute of Tuberculosis and Lung Disease, Shahid Beheshti University of Medical Sciences 3. Tobacco Prevention and Control Research Center, National Research Institute of Tuberculosis and Lung Disease, Shahid Beheshti University of Medical Sciences 4. Tobacco Prevention and Control Research Center, National Research Institute of Tuberculosis and Lung Disease, Shahid Beheshti University of Medical Sciences Background and Aim Since tobacco consumption is not illegal, people are often not considering it as an addictive substance. Cigarette and hookah contain nicotine which is highly addictive and Results in development of dependence. Nicotine, heroin and some opioids have a similar effect on the brain. It has been revealed that young smokers have a stronger desire and tendency to experience high risk behaviors and have a greater risk of substance abuse compared to non smokers. Also, rate of smoking among addicts is several times greater than this rate among non-addicts. In this study we are evaluating Smoking Pattern and Its correlation with Addiction among Substance Abusers. Methods In this descriptive cross sectional study. 487 cases referred to the rehabilitation centers and substance abuse clinics in Tehran were evaluated and smoking pattern and its correlation with initiation of substance abuse was studied by using a standard questionnaire. Results A total of462 person (95.9%) mentioned a history of smoking. There were 435 (92.4%) smokers which 261 (57.7%) had moderate or high nicotine dependence. A significant correlation was detected between first substance abuse experience or daily substance abuse during the first 2 years following smoking onset (P=0.006). Those who started smoking at a younger age in our study started substance abuse significantly sooner than others or developed a daily addiction to it. Using below formula, we can anticipate how Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S187 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall long after smoking experience one would probably experience their first substance abuse (P=0.001). First substance abuse experience age=7.72+0.78 (first smoke experience age) Conclusion A significant correlation exists between smoking and future substance abuse. Therefore, efforts must be made to prevent tobacco consumption in the first place. For those who are already smokers, preventive and supportive measures must be undertaken to prevent substance abuse especially in the first two years following smoking initiation. Keywords Smoking, Substance Abuse, Experience, Initiation The Efficacy of Group-Reality Therapy Approach in Reducing Depressive Symptoms and Preventing Relapse in Drug-dependent Adolescents Javad Asadolahi1, Mohammad Javad Asghari, Ebrahimi. Abad2, Sayed Ali Kimiaee3, Davood Razi Roodi4 1. MSc. Student- Department of Family Counseling, Ferdowsi University of Mashhad 2. Assistant Professor Department of Psychology,Ferdowsi University of Mashhad 3. Assistant Professor Department of Psychology,Ferdowsi University of Mashhad 4. MSc.of clinical psychology.Islamic Azad University Torbatjam of Mashhad Background and Aim One of the important things in reversion (relapse) of drug-dependence adolescents is the comorbidity of depression and substance abuse. The group-reality therapy is designed to help individuals monitor and control over their behaviors, take their responsibilities and make appropriate choices. The aim of this study was to evaluate the efficacy of the approach of group-reality therapy in reducing the symptoms of depression and preventing relapse in drug-dependent adolescents Methods In a quasi-experimental design, 20 drug-dependent adolescents were selected through availability sampling. All adolescents were resident in Mashhad Anonymous Addicts Forum, completed detoxification period successfully, and scored 14 or higher of symptoms of depression in Beck Depression Inventory (Second Edition). Then they were randomly assigned to both experimental groups (n = 10) and control group (n = 10). Experimental group received 10 sessions of group-reality therapy training and control group took no treatment during this period. The subjects of the study were evaluated by Beck Depression Inventory (Second Edition), morphine test before and after treatment, and after a twomonth follow-up. Data analysis was done by using chi-square test, z-test comparing test and analysis of covariance. Results The Results showed that group-reality therapy training can cause a significant decrease in symptoms of depression in addicted adolescents. Moreover, x2 Results showed a significant difference in the relapse frequency between the two groups (experimental and control). Conclusion Overall, the survey Results showed that group-reality therapy training is effective in reducing depressive symptoms and preventing relapse in drug-dependent adolescents Keywords Reality Therapy, Depression, Drug Dependence, Relapse Prevention, Adolescents The Efficacy of Mindfulness-Based Stress Reduction (MBSR) Group Therapy in reducing aggression of Addicts treated with Methadone Maintenance Javad Asadolahi1, Sayed Ali Kimiaee2, Zahra Tabibi3, Nafise Nezakati4, Masoumeh Mohammadi5 1. MSc. Student- Department of Psychology, Ferdowsi University of Mashhad 2. Assistant Professor Department of Psychology,Ferdowsi University of Mashhad 3. Assistant Professor Department of Psychology,Ferdowsi University of Mashhad 4. MSc. Student- Department of Psychology, Ferdowsi University of Mashhad 5. MSc. Student- Department of Psychology, Ferdowsi University of Mashhad Background and Aim Aggression is one of the most prevalent problems among drug addicts which has lead them to abuse drugs. The aim of current study is to survey the effect of mindfulness based stress reduction therapy on aggression reduction of addicts treated with methadone maintenance. Methods The plan type of quasi-experimental study was pretest – posttest with a witness group. Sampling was targeted and the case study of this quasi-experimental survey contained 20 addicts of Cheneran Occupational therapy camp who had gained high scores in Buss and Perry questionnaire. These 20 people were randomly placed into two groups as a witness group and an experiment group. Then the experiment group was subjected to 8 sessions of mindfulness based stress reduction therapy (mbsr) while the witness group didn’t receive any intervention. The data were analyzed through Univariate variance analysis. Results One way covariance showed that mindfulness based stress reduction therapy was effective in the posttest stage (P<0.05) Conclusion According to prevalence of aggression among drug addicts and effectiveness of mindfulness based stress reduction therapy, offering psychological services in order to reduce aggression and its underlying factors seems necessary. Keywords Mindfulness-Based Stress Reduction, Aggression, Opiate Addicts S188 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Investigate the Correlation between Indicators the NEO-Five Factor and Trust Interpersonal Relationship in the Addicts. Behzad Asbaghi1, Zahra Babazadeh2, Vida Aghazadeh3 1. Department of Clinical Psychology, Ardabil Branch, Islamic Azad University, Ardabil, Iran. 2. Department of Clinical Psychology, Ardabil Branch, Islamic Azad University, Ardabil, Iran. 3. Yong Researchers Club, Ardabil Branch, Islamic Azad University, Ardabil, Iran. Background and Aim Objective: The purpose of this study was to investigate the correlation between indicators the NEO-Five Factor and trust interpersonal relationship in the addict. Methods This study is a correlation. The research population of addicts referring to addiction camps in Tabriz in 2014 with a mean age (18 to 50) comprised. A total of 62 patients were selected for sampling, and collection of data from NEO Five-Factor Personality Inventory (NEO-EFI), and interpersonal trust scale Rempel and Holmes (IRS) was used. Data using Pearson correlation analysis, and were analyzed by SPSS 16. Results The Results showed that the index NEO neuroticism indexes the loyalty subscale (P value <0/02) and of the openness and predictability subscales (P value <0/008) had a significant negative correlation. Also indicators agreeableness with subscale predictability and the Conscientiousness of the whole scale interpersonal trust, respectively (P value <0/013), (P value <0/04) had a significant positive relation. Conclusion The Results indicate that these variables can be used as a counseling strategies used to help addicts. Keywords Indicators the NEO-Five Factor, Trust Interpersonal Relationship. The Role of Alexithymia in Predicting Of Depression, Anxiety and Stress Substances Abusers Behzad Asbaghi1, Tavakkol Mousazadeh2, Mohammad Narimani3 1. Department of Clinical Psychology, Ardabil Branch, Islamic Azad University, Ardebil, Iran. 2. . Department of Clinical Psychology, Ardabil Branch, Islamic Azad University, Ardebil, Iran. 3. Department of Psychology, University of Mohaghegh Ardabili, Ardabil, Iran. Background and Aim Objective: This study aimed to determine the role of alexithymia in predicting depression, anxiety and stress, drug abuse was conducted. Methods randomly. Depression scale, anxiety and stress (DASS), the Toronto Alexithymia Scale -20 (FTAS), was used for data collection. Statistical software SPSS 17, and methods of Pearson correlation and regression analysis were used to analyze the data. Results The Results showed that the total scale and subscales between alexithymia whole scale of depression, anxiety and stress subscales were significant positive correlations between the 0/22 there (P<0/05). Alexithymia (difficulty in identifying feelings with difficulty describing feelings) predicted depression drug abusers (P<0/001). Alexithymia (difficulty in identifying feelings and difficulty describing feelings with concrete thinking) predicted anxiety drug abusers (P<0/001). Alexithymia (difficulty in identifying feelings with difficulty describing feelings) predictors of stress in drug abusers (P<0/001). Conclusion Based on the Conclusions of this study, alexithymia predictive of anxiety, depression, stress and drug abusers. Keywords The Alexithymia, Depression, Anxiety, Stress, Substance Abuse. The Role of Psychosomatic Indicators in Predicting of Depression, Anxiety and Stress Substances Abusers Behzad Asbaghi1, Tavakkol Mousazadeh2, Mohammad Narimani3 1. Department of Clinical Psychology, Ardabil Branch, Islamic Azad University, Ardebil, Iran. 2. Department of Clinical Psychology, Ardabil Branch, Islamic Azad University, Ardebil, Iran. 3. Department of Psychology, University of Mohaghegh Ardabili, Ardabil, Iran. Background and Aim This study aimed to determine the role of psychosomatic factors in predicting depression, anxiety and stress, drug abuse was conducted. Methods This study is a correlation. 132 cases of drug abuse among patients referred to Tabriz addiction camps were selected randomly. Depression scale, anxiety and stress (DASS), Psychosomatic Inventory Index subscale (SCL-90) was used for data collection. Statistical software SPSS17, and methods of Pearson correlation and regression analysis were used to analyze the data. Results Findings showed that the overall scale of psychosomatic indices depression, anxiety and stress and its subscales were significantly correlated with 52/0 is (P<0/05). With the arrival of all of the regression equation determined psychosomatic psychosomatic indices that is capable of %32/3 of the variance in depression, anxiety and stress can predict (P<0/001). Conclusion Method: This study is a correlation. 132 cases of drug abuse among patients referred to Tabriz addiction camps were selected Based on the Conclusions of this study, psychosomatic factors predictive of anxiety, depression, stress and drug abusers. Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S189 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Keywords Psychosomatic Index, Depression, Anxiety, Stress, Substance Abuse. Comparison of Alexithymia and Anxiety and Stress between Addicts and Healthy Subjects Behzad Asbaghi1, Vida Aghazadeh2 1. Department of Clinical Psychology, Ardabil Branch, Islamic Azad University, Ardabil, Iran. 2. Yong Researchers club, Ardabil Branch, Islamic Azad University, Ardabil, Iran. Background and Aim This study compared the alexithymia and anxiety and stress between addicts and healthy people. Methods The study sample addicts referring to addiction camps in Tabriz in 2014 with a mean age (15 to 45) were formed. A total of 122 patients (60 addicts and 62 healthy subjects) were selected for sampling. Data collected from the questionnaires, the Toronto alexithymia Scale -20 (FTAS), and anxiety and stress scales (DASS), were used. Data with Mean and Independent T-test and SPSS 16 were analyzed. Results The Results showed that the alexithymia addicts and control group, a significant differences) P value< 0/000(, addicts mean (M = 66.96) and control group (M = 48.57). And there was significant difference between two group in anxiety and stress scales (P value <0/000), and mean in addicts and control group was respectively in anxiety (M = 21.77), (M = 12.77) and stress (M = 19.39), (M = 10.22). Conclusion This study shows that significant differences in alexithymia, anxiety and stress between addicts and healthy people. Keywords Alexithymia, Anxiety, Stress, Addicts. Smoking and Acute Myocardial Infarction (Female Versus Male) Elnaz Asghari1 1. Nursing and Midwifery School of Tabriz. Tabriz Medical University Background and Aim Acute Myocardial Infarction (AMI) has traditionally been considered a disease affecting mostly men because of smoking and hormonal issue. But nowadays it seems that the role of smoking as the main risk factor has changed in both genders. This study was to examine the smoking role among risk factors of AMI in both genders. Methods The study was conducted as a prospective cohort survey among patients admitted to CCU. All patients in one of the CCUs, selected accidentally, admitted with documented diagnosis of AMI were assessed during one year. Some socio- demographical characteristics of the patients recorded at the first day of the admission. Then those patients were followed up until discharge or death. Statistical analyses were performed with SPSS version 13.0. The data was analyzed by descriptive and inferential statistics. Regression analysis is used to predict the risk factors Results A total of 182 patients (140 men (68.6%) and 42 women (20.6%)) admitted with AMI were enrolled in the study. There were no difference in previous admission, death, or need for Coronary angiography among both gender. Women were on average 2 years older (64.74 versus 62.21, P< 0.0001), and had a greater prevalence of hypertension (76.2% vs 44.3%, P< 0.0001) but Men more often were smokers (45.7% vs 11.9%, P< 0.0001). Regression analysis indicated that smoking could predict 16 % and 18% of SD changes of AMI in men and women respectively. Conclusion In this study smoking is one the main risk factors for AMI in both genders. Although smoking is more prevalent among men, it is more harmful for at risk women. So the awareness needs to be directed towards eliminating controllable risk factors of fatal heart disease. Keywords Smoking, Acute Myocardial Infarction and Gender Decision to Quit among Female Substance Abusers, a Qualitative Study Elnaz Asghari1 1. Nursing and Midwifery School of Tabriz, Medical Sciense University of Tabriz Background and Aim Introduction: addiction in woman has too many disadvantages for their own and family members, so recognizing addiction quit reasons especially in women, is very important. The aim of this study has to explore effective factors on the decision to quit among female substance abusers. Methods This is a qualitative study undertaken with grounded theory approach. The Participants were 7 married addict females who were undertaken in quit rehabilitation course for the first time. Participants were selected using purposeful sampling and maximum variation. Data were gathered through face-to-face interviews and semi-structural questions. Data analysis was conducted using content analysis method. Results the main category explored in this study is “the wish to survive”, which includes three subcategories: 1- to feel threatened, 2- to get tired of the current condition and 3- “to keep family”. Most of the S190 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall main threat and encourage messages were from their spouse. Conclusion The Results of this study show that “husband” has the main role in females’ addiction condition and it’s quit, so if family background and context support the addict women, they may try rehabilitation. If governments and addiction treatment institutes make families show more compassion, motivation and support the result of quit decision seems to get better. Keywords Addiction, Married women, Decision to Quit, Qualitative Study Cognitive Behavioral Therapy for the Treatment of Personality Disorder in Crack Dependents Fatemeh Asgharzadeh1, Yahya Bahrini2, Faryma Naghdi3, Seyed Morteza Mosavi4, Ensyeh Sadeghi5, Ali Salesh Tabar6, Hossin Ali Ghanazadegan7, Masome Fadavi8, Katayon Razjoyan9 1. Clinical Addiction 2. Doctor 3. M.A Psychology 4. M.A Psychology 5. PhD.Olom Tarbiati 6. M.A Psychology 7. PhD Psychology 8. Clinical Psychology 9. Doctor Background and Aim Cognitive behavioral therapy for the treatment of personality disorder in crack dependents Methods In this research , we have used cognitive-behavioral therapy (CBT) for the treatment of 12 kinds of personality disorders in crack dependents . Personality diagnosis questionnaire used for measuring. 20 of dependents randomly placed in experimental group .They have used METHADON and CBT for treatment , but control group only received METHADON . We studied personality disorders of experimental & control group in 12 sessions. In this research we used of ANCOVA statistic. Results Showed that personality disorders improves in crack dependents in experimental group . Improvement in 3 personality disorders (schizoid - antisocial & narcissistic) didn’t show up. Conclusion After passing 9 months ; only one patient suffered a relapse in experimental group , but in control group , 4 patients relapse . Crack dependents were well to respond the CBT treatment Keywords Personality Disorder , Cognitive Behavioral The Relationship between Personality Characteristics and Social Support with Depression, Addiction Mojtaba Ashouri1, Shamsi Mohammadi2, Parvin Zolghadri3, Sara Abdi4, Ziaadine Rafiee5, Esmat Nasiri6, Rahim Ganjkhanlu7 1. Master of Educational Psychology, Urmia University, a Visiting Member of Payam Noor University 2. MA in Clinical Psychology, Rehabilitation Specialist Zanjan 3. Master of Educational Psychology, Urmia University, a Visiting Member of Payam Noor University 4. MA in Clinical Psychology, Rehabilitation Specialist Zanjan 5. MB in Clinical Psychology, Rehabilitation Specialist Zanjan 6. MA in Clinical Psychology, Rehabilitation Specialist Zanjan 7. MB in Clinical Psychology, Rehabilitation Specialist Zanjan Background and Aim We aimed to investigate the relationship between personality characteristics, social support and depression were addictive. Methods 350 cases of drug sampling were chosen using a random sample of 16 personality factors, social support questionnaire, completed the wax and colleagues and Beck Depression Inventory. Data obtained using the t test and stepwise regression were analyzed. Results The Results showed that the social Mtghyrhmayt and depression (p <0/01), personality characteristics, social support and depression in substance abuse (p <0/01), there is a correlation Conclusion The characteristics and social support could predict depression in addiction. Keywords Characteristics, Social Support, Depression and Addiction. The Relationship between Personality Traits and Personal Values and Attitudes Towards Drug Addicts Mojtaba Ashouri1, Masuome Rahbar2, Eskandare Rahbar3, Farzane Piran4, Sara Abdi5, Parvina Zolghadri6, Shamsi Mohamadi7 1. Master of Educational Psychology, Urmia University, a Visiting Member of Payam Noor University 2. MA in Clinical Psychology, Rehabilitation Specialist Zanjan 3. MB in Physiotherapy Assistant Rehabilitation Organization Intelligence city 4. MB in Clinical Psychology, Rehabilitation Specialist Zanjan 5. MA in Clinical Psychology, Rehabilitation Specialist Zanjan 6. Master of Educational Psychology, Urmia University, a Visiting Member of Payam Noor University 7. MB in Clinical Psychology, Rehabilitation Specialist Zanjan Background and Aim This study examined the relationship between personality traits and personal values and attitudes towards drug addiction. Methods Among 310 cases of population addicts Zanjan, 186 patients (99 females and 87 males) randomly selected and tested 16-factor Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S191 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall personality Cattle Inventory attitude questionnaire about finding value, Schwartz completed. Data analyzed using correlation, regression and chi-square test (x2) was analyzed. Results The Results showed that the relationship between drug attitude and personal values ??(except for power values??, tradition and self-reliance) are not significant. And the relationship between personality traits and attitude towards drug addicts in ¬ factor of 16 different. ¬ Draml of A (the painting - misanthropy), F (vitality - the heart of the dead), L (skeptical - the gullible), Q2 (dominant self - reliant on others) is significant and not significant Sayraml. Between personal values ??and personal characteristics in some variables, there is a significant relationship between the two forms Conclusion Correlation between factor A People - stained with the values of benevolence and conformity - Agent E rule - obey the values of strength and self-reliance - the F vitality - Dell ¬ dead values, universalism and conformity - the L skeptical - gullible value benevolence - the Q2 dominant self - reliant on others the value of self-reliance and negative: I Draml critical - factor stubborn self-reliance and distrust values disquieting - Atmadtvam calmly values of benevolence and self-reliance - Q4 operating nervous tension cents worth. No other variables are significant. Comparison Emotional Intelligence, Coping Strategy and Cognitive Emotion Regulation in Addict and None Addict people. Mahdiye Ashouri , Rogayeh Ashourpour , Reza Kazemi , Azra Gaffari 1. ashouri 2. ashourpour 3. kazemi 4. gaffari 1 2 3 4 Background and Aim drug abuse and addiction problem one of the important problem in the current world that accompanied with healthy, socially and economical pathology. Psychiatry association of USA said that the main feature of dependency to drug abuse cause that despite of problems in drug abuse, addicted person continue to abuse. The main purpose of this research, comparison Emotional Intelligence, Coping strategy and Cognitive Emotion Regulation in addict and none addict people. Methods This present research is descriptive and comparative model. The population is persons applicant person to MMT center in Tehran. they were selected by convenience sampling that compose of 150 addicted person and 150 none-addicted person Results Conclusion indicate that emotional intelligence and coping strategy have significant correlation among addicted and none-addicted person. Keywords Emotional Intelligence, Drug abuse, Addiction Effectiveness of Positive Psychology Interventions on decreasing the Depression, stress, Social Malfunction in women with Drug Abuse in Hamedan Town Ship Maedeh Ashrafi1, Behrouz Karkhaneie2, Sareh Roshanpour3 1. M. A Degree in General Psychology.Hamedan Science and Research Branch, Islamic Azad University 2. Assistant Professor in Hamedan Medical Science University 3. MSc of Food Since Engineer Islamic Azad University of Damgan Background and Aim Since the Vulnerability and Psychological depression and Stress signs in addicted Women are more high in compare with the other women, so, Performing mental investigations and Servicing beside the positive psychological interventions from the Mental Health Systems absolutely Results in highly improving their life levels. Purpose: The goal of this research is formulate and determing the effectiveness of positive psychology Interventions on dereasing the depression, Stress, Social malfunction in women with drug abuse in Hamedan township. Methods About 30 volunteers woman Selected as a sample group. (15 women as experimental group and 15 women as Control group). The research plan based on pre- test and post- test on the Control group. The research tool is GHQ- 28 method. The teaching intervention performed on the experimental group during 8 Sessions (90 minutes). Data analyzed based on the multi variables Covariance Statistical test. Results The Results showed that teaching the Psychological Positive interventions Results in increasing the Psychological health level and decreasing the levels of depression, Stress, Social mal function of addicted woman with drug abuse. Conclusion According to the investigation from the hypothesizes analysis, it can be nor the worthing to said that the levels of Psychological disorders in the women decreased during the teaching Sessions, as well. Keywords Psychological Positive Interventions, Mental Health, Women, Drug show that Emotional Intelligence have significant difference among addicted person and none-addicted person. Coping strategy and self-regulation also have significant difference among addicted and none-addicted person. S192 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Social Support and Drug Tendency in Student indicated that the material craving scores, there was no significant difference in NA. And the Results showed that the number of slip and craving scores in the methadone group there was a significant relationship. Saeid Askari1, Saeid Sadeghi2, Zahra Hasani3, Zahra Sahragard4 1. Razi University 2. Shahid Beheshti University 3. Razi 4. Razi Conclusion Background and Aim The purpose of this study is the relationship between social support (family) with a tendency to addiction. Keywords Methods The study sample consisted of all students in the Faculty of Social Sciences, Razi University, selected using random sampling. Correlation coefficient was used to analyze the data. Results Showed that social support has a significant negative correlation with the tendency to addiction. Conclusion Increasing social support resources and enhance social supports quality can reduce the tendency to be addictive. Keywords Social Support , Drug Tendency , Student NA group, Methadone Maintenance Treatment, Craving Evaluation of Self and Spiritual Health and Marital Satisfaction among Male Addicts Recovering in NA and MMT Groups in the City of Susa Satar Kaikhavani1, Koorosh Sayemiri2, Mahre Asmael Chegani3 1. Assistance Professor. Department of Psycology, Ilam Science and Research Branch, Medical Sciences University, Ilam, Iran 2. Assistance Professor. Department of Psycology, Ilam Science and Research Branch, Medical Sciences University, Ilam, Iran 3. MA in Psycology, Department of Psycology, Ilam Science and Research Branch, Islamic Azad University, Tabriz, Iran. Background and Aim Comparison of Craving Score Based on Imagery-Induced Craving in Addicts under Methadone Treatment in NA and Associations Referred to these Centers in the City of Susa Satar Kaikhavani1, Koorosh Sayemiri2, Mahre Asmael Chegani3 1. Assistance Professor. Department of Psycology, Ilam Science and Research Branch, Medical Sciences University, Ilam, Iran 2. Assistance Professor. Department of Psycology, Ilam Science and Research Branch, Medical Sciences University, Ilam, Iran 3. MA in Psycology, Department of Psycology, Ilam Science and Research Nranch, Islamic Azad University, Ilam, Iran. Background and Aim Drug addiction, is today one of the fundamental problems of human life is considered. This study compares craving scores based on imagery-induced craving in addicts treated with methadone detox Narcotics Anonymous, which has been carried out. Methods In this study the cause - a comparison of 80 patients (40 men and 40 women methadone NA) man recovering addict who spent detoxification period is included. Results The test evaluates the different groups of drug craving, as well as the validity and reliability of the localization is perfect, most of the features of this phenomenon can be detected before and after treatment to determine how successful protocols in reducing craving and relapse prevention addiction help. showed that the highest score among test-related cravings is tramadol test. Results also showed that there was no significant difference between the two groups cravings. And the chi-square test Drug abuse is a disaster for consumers, their families and society, Therefore, as a major cause of social, economic, health, criminology known. This study aimed at comparing spiritual health, restraint and marital satisfaction in married male addicts in Narcotics Anonymous (NA) and methadone maintenance therapy (MMT) was performed. Methods In this comparison, the number of 25 persons men volunteers (members of Narcotics Anonymous and the 25 subjects MMT, with an age range of 60-30 years with at least 6 months of abstinence from food, the city of Susa, the scale of spiritual well Pvlvtzyn and Ellison restraint, self-made and completed marital satisfaction. Results Significant test of Leuven (0/697) more than 5 0/0 indicating equal variances between the two groups. So the average recurrence rate was not significantly different between the groups. Conclusion The following Results were obtained from this study: 1. Between the two groups in terms of marital satisfaction na and there are significant differences 0.2 mmt. Mmt between na and there are significant differences in terms of spiritual health. Three. Between the two groups in terms of self-mmt na and there are significant differences. Keywords Spiritual Well-Being, Self-Control, Sexual Satisfaction Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 S193 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Effect of TCS-OX2-29 Orexin-2 Receptor Antagonist Microinjected into the Nucleus Accumbens on Morphine Sensitization by Conditioned Place Preference Paradigm in Rat Nasim Assar1, Dorna Mahmoudi2, Seyede Zahra Mousavi3, Abbas Haghparast4 1. Department of Toxicology & Pharmaceutical Sciences Branch, Islamic Azad University (IAUPS) 2. Department of Toxicology & Pharmaceutical Sciences Branch, Islamic Azad University (IAUPS) 3. Department of Toxicology & Pharmaceutical Sciences Branch, Islamic Azad University (IAUPS) 4. Neuroscience Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran Background and Aim It has been reported that orexins (hypocretin) are important neuropeptides in reward. Previous studies have shown that orexin receptor in the nucleus accumbens (NAc) is necessary for development of morphine place preference. The present study extended the role of orexin receptors within the NAc in opioid sensitization. In this study, the effects of bilateral administration TCS OX2 29 of, orexin-2 (OX2) receptor antagonist, on the acquisition of morphine sensitization by morphine-induced conditioned place preference (CPP) in rats were investigated. Background and Aim because ability to regulating emotions is very important in human behavior, recognizing affect of them in tendency to substance abuse and addiction can be useful in primary prevention. The aim of this research is comparing Difficulties in Emotion Regulation between people with substance abuse and people without. Methods 50 men aged 25-50 with substance abuse and 50 men with the same age range without substance abuse were participated in this study. Difficulties in Emotion Regulation Scale (DERS) administered on both groups. Means of Difficulties in Emotion Regulation score in both groups were analyzed by SPSS and independent t-test. Results the mean of Difficulties in Emotion Regulation (x=128.72) in substance abuse group was higher than normal group (x=65.32). In other word the difference between two groups in mean of scores was statistically significant (p> 0.05, t= 33.31). Conclusion Difficulties in Emotion Regulation in substance abuse group are higher than normal group. Keywords Methods Adult male albino Wistar rats were used in this experiment. Rat were bilaterally implanted by two cannulae in the NAc, and received intra-NAc infusions of OX2 receptors antagonist TCS OX2 29 (2, 10 and 20 nM/side) 10 min before injection of morphine during sensitization period. In this period, animal received repeated administration of morphine once daily for three days (sensitization period) followed by 5 days free of the drug. Then, CPP paradigm has been performed for evaluation of morphine rewarding properties. Difficulties in Emotion Regulation (DERS), Addict, Non Addict. Cigarette Smoking Evaluation of Prevalence and Causes of Male Students in Tabriz University Hafez Atapour1, Mahdi Zare2, Babak Mohammadi3, Amir Ahmadi4 1. Master of Clinical Psychology 2. Master of Clinical Psychology 3. Master of Clinical Psychology 4. Master of Clinical Psychology Results Data showed that bilateral administration of TCS OX2 29 into the NAc dose-dependently reduced acquisition of morphine sensitization. Conclusion Our findings indicated that OX2 receptors within NAc are involved in acquisition of morphine sensitization. Keywords Orexin, Nucleus Accumbens, Morphine Sensitization, Conditioned Place Preference, Rat Comparing Difficulties in Emotion Regulation between People with Addict and Non Addict. Rozita Astaneh1 1. Tehran Background and Aim Tobacco is the most common form of nicotine that is being smoked in forms of: cigarettes, cigars and pipe. Nicotine is addictive, just like cocaine and heroin. According to the world Health Assessment, there are approximately one billion smokers in the world that consume 6 trillion thread cigarettes each year. In addition, tobacco is contributed to the death of 3 million. Smoking effects include: urinary tract and bladder cancer, lung cancer, laryngeal cancer, obstructive pulmonary disease, and etc. It also increases blood cholesterol, and causes coronary artery disease. The Results also show that there is a significant negative relationship between mental health and addiction potential. Methods This study is aimed to determine the outbreak and the causes of tendencies toward cigarette smoking among male students in Tabriz University. 169 male students in Tabriz University were selected by random cluster sampling. This study was cross-sectional, descriptive analysis of the data required were collected through a questionnaire. The data were analyzed by chi-square test lead. S194 Archives of Iranian Medicine, Volume 16, Number 5 (Suppl. 1), May 2013 The 8th International Congress on Addiction Science 10 - 12 September, 2014, Tehran Razi Hall Results The Results showed that 38/5 % of students smoke. Also, there was a significant relationship between the age of entering college, academic failure of students and the tendency toward smoking. The chi-square test Results showed that there is a significant relationship between cigarette smoking and smoking in the families of the students (p=0/001). Conclusion This study showed that there exists a significant relationship between the age of entry to university, academic failure, family smoking, and smoking in students. So we can say that the most important factors of smoking among students are: family, friends, and academic problems. The Results of these researches are consistent with the findings of Ghasemi (1382). Keywords Prevalence, Causes, Trends, and Smoking; Students Reviews Using Drugs, Alcohol and Psychotropic Drugs Among Adolescents and Youth 15-35 Years Old Students and Non-Students in Tabriz. Hafez Atapour1, Mahdi Zare2, Amir Ahamadi3, Babak Mohammadi4 1. Master of Clinical Psychology 2. Master of Clinical Psychology 3. Master of Clinical Psychology 4. Master of Clinical Psychology Background and Aim One of the important issues and challenges in recent years that have been appeared seriously in Iran among youth, students and non-students, is the issue of drugs, alcohol and psychotropic drugs. Therefore, the need to scientific study and as far as possible accurate state of the current substance abuse to develop prevention programs by community mental health practitioners at the national level makes it necessary. Methods The aim of the present research was to study drugs, alcohol and psychotropic drugs among adolescents and young adults, 20-35 years old students and non-students in Tabriz. The study sample of this research were youth 15-35 years old in Tabriz that was conducted from 4 region of Tabriz by cluster random sampling. And a sample of survey data from 1600 was used to calculate and collect demographic questionnaire and the Beck Depression Inventory and a questionnaire. Results To investigate the prevalence of stimulants, alcohol, psychotropic drugs, Scheffe and chi-square tests were used. Results showed a significant difference between students and non-students of the smoking and alcohol (p=0/05); and, psychotropic drugs and stimulant medications of this groups showed no significant difference (p=0/243). Conclusion Results of this study showed that smoking rate among students is 18/5 percent and among non-students is 20/1 percent. Chi-square test showed that there are significant differences of smoking and alcohol between the two groups. In other words, students have to consume more alcohol. Students compared to other students in the use of stimulant medications do not show significant differences. Results showed that depression is significan