Fish Diseases.wps
Transcription
Fish Diseases.wps
Mouth Fungus Treatment for Mouth Fungus: One day, you’re faced with one of your fish, who has patches of white fuzzy stuff on him and you start thinking to yourself, ” I need some medicine quick to kill this fungus, because if it’s white and fuzzy, then it must be a fungus, right?!” Wrong! White fuzzies that occur on otherwise normal skin and fins of a fish are much more likely to be due to a Flexibacter infection, which is a bacterial infection and not a fungal one. True fungus (Saprolegnia) can appear on open, raw or wounded areas, that is, it grows on dead tissue and it is seen much less often in the hobby than a Flexibacter infection is. The majority of fish medications with the word “Fungus” in their title actually contain antibiotics to kill bacteria! The fish drug companies know that most things white and fuzzy are not due to a fungus but rather are due to Flexibacter and although they give you the correct drug to treat the problem, they perpetuate the myth that all things white and fuzzy must be due to a fungus! Treatment Options The treatment of Flexibacter is best accomplished by feeding medicated food, containing oxytetracycline, tetracycline or kanamycin. Other antibiotic-laced foods may contain antibiotics, to which Flexibacter is resistant, such as ormetoprim and sulfadimethoxine, so, substitutes are not acceptable. The unfortunate problem with this disease is that the infected fish rapidly becomes ill and stops eating, especially if it has “Mouth Fungus”, therefore, treating with medicated food may not be an option. Antibiotics in the water would be the next treatment option. It is best to perform this type of antibiotic treatment in a separate “hospital” tank as this removes the sick fish from the healthy ones in the main tank, does not unnecessarily expose the healthy fish to antibiotics and medication costs will be lower when treating in a smaller tank. However, if multiple fish are infected in the main tank, then it may need to be treated. Kanamycin (Kanaplex, Kanacyn) daily in the water is a great first choice for treating Flexibacter and it usually does not harm the biological filter (the “good guy” bacteria). As an alternative, erythromycin (plain Maracyn) or tetracycline can be used. When using either erythromycin or tetracycline in an established (“cycled”) tank, be sure to watch your water parameters, as these two antibiotics may harm the biological filter. Likewise, nitrofurazone (Fungus Eliminator) works well against Flexibacter but can harm the bio filter. Cephalexin (Keflex, Velosef) can be used at the rate of 250 mg per 10 gallons daily preceded by a 25% water change but this cephalosporin antibiotic is harmful to the biological filter. For those fishkeepers living outside of the United States, who are unable to obtain the antibiotics mentioned, then either Waterlife’s Myxazin or Interpet’s AntiFungus and Finrot would be the best treatment to choose. Other antibiotics, which may be effective against Flexibacter are nifurpirinol, acriflavine, chloramphenicol and malachite green. Disinfectant dips, such as with quaternary ammonium, and prolonged immersion in potassium permanganate or copper sulfate have been advocated. Aeromonas, another gram-negative bacterium ubiquitous to one’s tank, often infects a Flexibacter-infected fish at the same time (secondary bacterial infection) and is thought to be the cause of death in many cases of Flexibacter infection. Therefore, treatment should also be aimed at this bacterium. If you are already using kanamycin (Kanacyn) in the water to treat the Flexibacter, it will also treat the Aeromonas. If you are alternatively using either erythromycin (plain Maracyn) or tetracycline, then treat simultaneously with minocycline (Maracyn-Two) for the Aeromonas. Both kanamycin and minocycline are antibiotics, which are considered not to be harmful to the biological filter, but at high dosages, kanamycin can harm the bio filter. Be sure to remove all activated carbon when treating with antibiotics in the water. All antibiotic treatment should be continued for a minimum of 10 days and the decision for treatment beyond 10 days will depend upon how well one’s fish is recovering. Bring the water temperature down in the main tank until it is at 75-76ºF (24ºC), to slow the growth of Flexibacter. The water temperature in the hospital tank must not go above 76ºF (24ºC) for the duration of treatment. Additionally, increasing aeration, which improves oxygenation in the tank, will help to provide conditions less suitable for Flexibacter. In short, treatment for a Flexibacter infection in a hospital tank would look like the following… • Feed medicated food containing oxytetracycline, tetracycline or kanamycin. Kanamycin (Kanaplex or Kanamycin) daily in the water for both Flexibacter and Aeromonas. As an alternate choice, Maracyn (erythromycin) for Flexibacter and Maracyn-Two (minocycline) for Aeromonas can be used in the water. Overseas fishkeepers can use either Waterlife’s Myxazin or Interpet’s AntiFungus and Finrot. • Decrease the temperature to 75-76ºF and no higher. • Increase aeration. • While care should always take place when treating sick fish, this strain of Flexibacter cannot be transmitted to humans. Flexibacter columnaris, most recently named Flavobacterium columnare, is a bacteria that grows in layers, one on top of the other, giving it the appearance of “columns” or “haystacks” under the microscope and this is what gives us the white fuzzy look with our naked eye. Flexibacter is a thin gram-negative rod bacterium that is an ubiquitous organism, meaning that it is ever-present in one’s tank water, though the organism will only cause disease in fish that are undergoing stress. The specific conditions and stressors identified as setting up the right conditions for a Flexibacter infection are: 1. Sudden increases in water temperature. 2. Overstocking. 3. Infrequent water changes. 4. Low water oxygen (O2) content. 5. Elevated nitrite levels. 6. Uneaten food in the tank, which supports growth of Flexibacter. In general, poor water conditions will pave the way for a Flexibacter infection, so regular maintenance with partial "water changes are a must for a healthy tank. Mouth Fungus: The white patches often have a reddish rim around them and within 24 hours, they can quickly form an ulcer (raw open area in the skin), which is shaped like a circle and then it enlarges. The ulcers may sometimes have a yellow or orange color to them due to the piling of pigmented bacteria upon each other. If an ulcer penetrates into the body deeply, this leads to septicemia. The symptoms of a Flexibacter infection may include sluggish activity and a poor to absent appetite. The treatment of Flexibacter is best accomplished by feeding medicated food, containing oxytetracycline, tetracycline or kanamycin. Other antibiotic-laced foods may contain antibiotics, to which Flexibacter is resistant, such as ormetoprim and sulfadimethoxine, so, substitutes are not acceptable. The unfortunate problem with this disease is that the infected fish rapidly becomes ill and stops eating, especially if it has “Mouth Fungus”, therefore, treating with medicated food may not be an option. Freshwater Velvet Velvet (Oodinium or Piscinoodinium) is caused by a parasite that attaches to the outside of your fish, on its’ skin and gills. Piscinoodinium limneticum is the the type of Velvet infecting aquarium fish in North America, while Piscinoodinium pillulare infects those in Europe and Malaysia. The most susceptible fish to Velvet infections are the anabantids (e.g. bettas and gouramis) and cyprinids (e.g. barbs, danios and rasboras). Fry and tadpoles are particularly susceptible to it. Many cases of unexplained fish death can be attributed to Velvet heavily infesting the gills, that you usually cannot see easily with the naked eye. A flashlight and magnifying glass can assist you in seeing the Oodinium parasite. Shine the light on the fish's body and if it looks like it is covered with a fine gold or rusty mist or with a yellow-grayish powdery coating, then this is likely Velvet. By the time that a fish shows the characteristic gold or rust-colored coating, it is heavily infested. A fish with Velvet will eventually act sick, have clamped fins, scratch against rocks, gravel or tank walls (flashing), have a loss of appetite and may lay motionless. Treatment The entire tank needs to be treated when treating for Velvet. A “white spot” remedy such as RidIch+ should be used. Maracide may be used for small fry and is usually effective with bettas. When using RidIch+, always precede each daily dosage with a 25% water change, be sure that your water parameters (pH, ammonia, nitrite and nitrate levels) are normal and follow all pertinent instructions included with the medication that you have chosen. Continue the treatment for three days after the coating has completely disappeared and typically treatment should last for as long as 10-14 days. Reducing light in the tank helps to kill Velvet. Do not share equipment such as nets, between your tanks, to avoid spreading this parasite. Pop-eye Some day you may find, as you are staring into your favorite fish’s adorable eyes, that *gulp* one of his eyes is HUGE! Your fish is most likely suffering from pop-eye, which is also known by the medical term, exophthalmus. Humans with an over active thyroid can have exophthalmus and if you remember Marty Feldman from the movie “Young Frankenstein”… he had pop-eye! Some fish, such as the Black Moor, normally have eyes that are bulging or “telescoping” and this is not considered to be pop-eye. Pop-eye is not a disease itself, but rather it is a sign of some underlying problem. The signs of pop-eye are that one or both eyes start to bulge out. Over the next week, the eye may bulge out even more and sometimes to the point that your once adorable fish is really quite grotesque to look at (the infamous Quasimodo stage!). You may see a large ring of white “skin” around the base of the eye. This tough tissue, that helps to hold the eye in its’ socket, is being stretched as the eye bulges. Your fish may show other symptoms such as being less active and not eating well. The eyes bulge out abnormally in pop-eye because of an accumulation of fluid either in the eye itself or behind the eye. The many causes of pop-eye include infections from bacteria, viruses and parasites, as well as from water nitrogen supersaturation (gas bubble disease), water quality problems, tumors, internal (metabolic) disorders and nutritional deficiencies. Treatment of pop-eye is based on identifying and treating the underlying problem. Gas Bubble Disease is a result of supersaturation (excess levels) of the water with the gas, nitrogen. Supersaturation occurs whenever the pressure of a gas in the water is higher than the pressure of the same gas in the surrounding atmosphere. When there is this difference between gas pressures, the gas gets pulled too quickly out of the bloodstream, leaving gas bubbles behind. This is what happens to SCUBA divers who ascend too quickly and create a big difference in gas pressures, which leads to the diver getting gas bubble formation or the “bends”. In fish, gas bubbles can accumulate behind the eye, making it bulge outward. Water in a newly filled tank will be supersaturated with gases and you will see the gas bubbles covering the inside of the tank. The more that the water is agitated as you are pouring it in for the first time, the less supersaturation you will have. Agitation of water releases gas from it. Normal aeration will speed up the time that it takes for this excess gas to leave the water. When the bubbles on the tank disappear, then it is safe to put your fish into the new water. High-powered powerheads, that shoot streams of air into your tank’s water, can lead to nitrogen supersaturation. Treatment in this circumstance would be to turn down the powerhead water stream adjustment to its’ lowest setting and allow the air pump to be the only source of air. For the next few days, observe your fish. If the pop-eye starts to go away, then it was due to nitrogen supersaturation. If there is no change or the condition worsens, then the popeye is most likely due to an infectious cause and probably a bacterial one. An excess of nitrogen gas can also occur as a result of a large build-up of nitrites and nitrates in the water and has been seen in deep wells and frozenover ponds and lakes, but probably does not happen to a significant degree in the aquarium. It is always important however to maintain excellent water quality for your fish. Under normal circumstances, there should be no measurable nitrites and the nitrates should be kept at 20 ppm or lower for all but the most sensitive species. The bacterial causes may manifest themselves as septicemia from such organisms as Aeromonas, Pseudomonas and Edwardsiella, all gram-negative rod bacteria. To diagnose septicemia, you should look for red blotches or red streaks on the body and fins. Bloody splotches at the base of the pectoral fins are often the first indication of septicemia. It is when the bacterial infection attacks the internal organs that the eyes begin to collect fluid. If your fish is still eating, treat by feeding antibiotic food. The most effective medicated food is Medi-Gold, which contains three antibiotics, including kanamycin. Romet B and Tetra medicated food for bacterial infections are alternatives to use, but the Tetra brand food may be less effective due to bacterial resistance that has developed to its’ antibiotic, tetracycline. If your fish has stopped eating or seems to be quite sick even with medicated food, then he should be treated with antibiotics in the water. The antibiotics kanamycin (Kanacyn) and minocycline (Maracyn-Two) have gram-negative rod bacterial coverage and can be used to treat septicemia. Other bacterial causes of pop-eye are from Mycobacteria (fish TB) and Nocardia. Fish infected with these bacteria tend to waste away and may have open ulcers on their bodies. Few studies have been performed to determine There has been some reported success with minocycline (Maracyn-Two) and kanamycin (Kanacyn). Interestingly, minocycline which antibiotic is best to treat fish TB. successfully treats Mycobacterium marinum (fish TB) in humans! Viral causes of pop-eye have been identified in the fishing industry in channel These viral diseases cannot be treated with medication and all fish must be destroyed, as it is very contagious. Even the survivors of these catfish, trout and salmon. viral diseases are destroyed because they then become carriers of the virus with the potential to spread it to healthy fish. Pop-eye is very rarely a result of such parasites as Ichthyophonus and flukes. The fungal-like organism, Ichthyophonus hoferi, formerly known as Ichthyosporidium, is not the same as Ich (Ichthyophthirius multifiliis). The Swinging Disease or Tumbling Disease, as fish infected with it rock, sway and even tumble as they swim. No treatment is known and affected fish should be removed from the aquarium and destroyed. Eye flukes (Diplostomum) cause the eye disease that it causes is known as to become cloudy, on occasion to bulge and often leads to blindness. This parasitic infection can only result from a fish being exposed to an intermediate host in its’ life cycle and usually that’s a snail. An inadequate diet may result in pop-eye. In this circumstance, you would also expect to see other signs of severe starvation or malnutrition, such as curvature of the spine. It is important to provide a varied diet to meet the nutritional requirements of your fish. Remember that flake and freeze-dried foods provide moderate nutritional adequacy, pellet and frozen foods provide high adequacy and live foods provide the highest. Pop-eye may be seen with dropsy, which is a condition in which fluid accumulates in the abdomen as a result of dysfunction of the internal organs. A fish’s scales will stick out and away from the body, giving it a “pinecone” appearance. Also, the underside or belly may look swollen in dropsy. This condition is very often fatal yet some within the goldfish community boast success when treating dropsy in its’ earliest stages. This treatment includes treating your fish for the first three days with a medication, such as Rid-Ich+, for external parasites in a hospital tank. This is then followed by rapidly raising the water temperature to 86*F, using extra aeration to keep the oxygen levels high and treating for a bacterial infection as outlined above for septicemia (e.g. feed Medi-Gold and/or use Kanacyn or Augmentin in the water), for as long as 2-4 weeks. Epsom salts are to be used at the rate of 1/8 of a teaspoon per five gallons of water to reduce swelling. Do not use aquarium or other similar salts as this may worsen the swelling. A bulging eye may be seen as a result of injury. If both eyes are affected, then trauma is unlikely to be the cause. Finally, pop-eye can very rarely be the result of a tumor, located behind the eye, pushing it outwards. The good news is that pop-eye is not often fatal, especially if given proper treatment. Pop-eye will sometimes even go away on its’ own with no treatment. As pop-eye is generally not very contagious, one fish expert, Dr. Chris Andrews, recommends observing your fish with pop-eye, while left in the main tank, to see if he gets better on his own or not. If the other previously healthy fish in the tank begin to get pop-eye, he then recommends isolation and treatment of the affected fish. I would advise that you search carefully for the cause of the pop-eye as discussed in this article and treat accordingly. If you cannot figure out the cause, then I recommend treatment with either Kanacyn or Maracyn-Two, for a possible bacterial infection, in a separate hospital tank. While the main tank may be treated with these antibiotics without harming its’ biological filtration, treating in a hospital tank allows you to isolate the sick fish from the others and medicating a smaller tank means lower medication costs. Even with proper treatment, your fish may be left with a grotesque eye and fish have even been known to “lose” the eye, that is, the eye becomes detached from its’ socket. Losing an eye is not necessarily traumatic for a fish. Fish can live a relatively normal life with just one eye, except that they can have problems with depth perception, that is, knowing how close or how far things are away from them. This can make swimming and eating a bit of a challenge. A fish that is blinded in one eye should not be destroyed, as they most often can live out a healthy and full life! DROPSY DESCRIPTION: A condition in which the internal organs, specifically the kidneys, fail, leading to fluid accumulation within the body. CAUSE: Unknown. May be bacterial in origin from Aeromonas or Mycobacterium, viral, parasitic from Costia as implicated in goldfish, water quality problems, nutritional deficiencies or abdominal tumors. SIGNS: Markedly swollen abdomen, scales sticking out and away from the body giving it the appearance of a pinecone, pop-eye, rapid gill breathing. SYMPTOMS: Poor to no appetite, sluggish behavior. PROGNOSIS: Very poor. Most cases are fatal. TREATMENT: Most cases of dropsy are diagnosed when it is too far advanced for any treatment to be effective, so euthanasia should be performed. If dropsy is caught very early, then it may respond to 1. Romet B or Medi-Gold (antibiotic foods)** for two weeks. 2. Maintaining the water at 84-86*F for two weeks. Be sure to provide extra aeration/oxygenation when treating at these high temperatures because warmer water holds less oxygen. 3. Abdominal swelling may be lessened by adding Epsom salt at the rate of 1/8 teaspoon per every 5 gallons of water, as it will draw fluid out of your fish. Never use aquarium or other types of salt, as these will pull even more fluid inside of your fish. 4. Always remove your fish with dropsy from the main tank and treat in a hospital tank. 5. Consider treating with RidIch+ or Maracide for external parasites. **Use kanamycin (Kanacyn) or minocycline (Maracyn-Two) as a bath, if unable to find medicated food, for 10-14 days. **The best antibiotic to be used for prolonged immersion, which can only be obtained from your Vet, is tauted to be Augmentin (amoxicillin/clavulanic acid) 500 mg tablet crushed per every 10 gallons water after a 25% water change has been performed, daily for 10-14 days, though I have been disappointed with its results in tropical fish. Feeding antibiotic food is the best course to follow. Once a tropical fish with dropsy has stopped eating, in my experience, it uniformly dies. The goldfish community has had a different and much more encouraging experience with successfully treating dropsy than the those with tropical fish. Fin Rot Cause: Bad water quality or exposure to other infected fish. Contagious. Symptoms: Pieces of the fins may appear tattered, shredded, or disintegrating. The edges of the fins may appear black or grayish in color. The fish may be lethargic, have clamped fins, or be hiding. Treatment: Tetracycline, Kanacyn, Maracyn2, TMP Sulfa Septicemia (VHS) No-Treatment Causes : Results from uncycled tanks and ammonia spikes, blood-born pathogens that cause bacterial infections. Symptoms: Bright red streaks on fins and may have patches of reddish coloration on body. Erratic swimming and may hyperventilate. Symptoms: Redness on fish, bloodstreaks on skin without apparent injury, especially blood streaks in the fins, inflamed blood vessels in the skin and at fin bases stand out, small haemorrhages around eyes, loss of appetite, sluggish or very sluggish behavior Clinical signs of SVC First signs of the disease may be a change in behavioral patterns of the fish. Fish may congregate in slow–flowing water, near pond banks, or lie on the bottom. Over time, the rate of respiration will decrease, as will reaction to stimulation and swimming speed. As the disease progresses, the fish become sluggish and may swim and lie on their sides. Externally, the fish can exhibit a number of non–specific physical signs including darkening of the skin, swollen abdomen, exophthalmia (pop–eye), hemorrhages in the skin, gills and anterior eye chamber, anemia and pale gills, and a protruding vent. Internally, the signs are dominated by building up of fluid (edema) in all organs and in the body cavity, hemorrhages in the swim bladder, and inflammation of the intestines. Temperature and seasonality Research has shown that the optimal temperature for development of SVC in experimentally infected carp is between 16 and 17° C. At this temperature, 90 percent of the fish died within 5 to 17 days after being infected. At lower temperatures, 11–15° C, the percent of fish that died was similar but the mortality was delayed (2–3 weeks). Mortality was reduced at temperatures between 17 and 26° C. The optimum temperature for in vitro virus replication is 20–22° C. Other experiments have investigated the influence of increasing and decreasing temperatures on the rate of disease. Research has also demonstrated that a gradual decrease of temperature (11 down to 5° C) caused low mortality, while increasing temperature back to 20° C caused massive mortality as the temperature changed from 7 to 14° C. These results correspond with the field observations that most SVC outbreaks occur in the spring with warming temperatures. What are the signs of VHSv? (Not all fish will exhibit symptoms) • Bulging eyes • Pale gills • Darkening overall color • • • Distended (fluid-filled) abdomen Bleeding around the eyes, bases of the fins, sides and head Corkscrew swimming behaviour Treatment: Maracyn-2, Oxytetracycline Hydrochloride Powder, water changes and testing to try to improve water conditions. FUNGAL INFECTIONS: True Fungus Causes: Bad water quality or exposure to another infected fish. Symptoms: Cottony tufts on fins and body. Lethargic. Clamped fins. Treatment: Kanacyn, Mardel MarOxy. Fish Tuberculosis(TB) Causes: Mostly found in saltwater fish, but occasionally in freshwater species. Caused by the pathogen: Mycobacterium spp., mostly M. piscium and M. marinum. Symptoms: Open sores; red or pink in color. Inflamed sores. Deep ulcers. Lethargic, no appetite, may become anorexic. Appears to waste away and you may see significant weight loss. The spine may begin to curve, causing difficulty in swimming. The fish will hide and clamp it's fins. Treatment: Kanamycin Sulfate; Kanamycin with Isoniazid. *******NOTE: Fish tuberculosis, although not in the same form, IS contagious to humans with open cuts on their hands so if you think you may have an infected fish please make sure you wear gloves when handling the fish, the water, or anything that has been in the tank. Ick Causes: Parasites in the water. can get it from improperly treated water (water that has not been dechlorinated). Highly contagious so may contract it from other fish. It is more likely to infect severely stressed fish and fish that are trying to adjust to drastic temperature and/or pH changes. Symptoms: Small white granules covering the fish as if they've been sprinkled with salt. The fish will flash and dart and try to rub against anything in the tank. Hiding. May gradually become more and more listless. Fish may hang near the surface of the water. Treatments: Maracide, Kanamycin, CopperSafe (Note: Do not use CopperSafe if you have invertebrates such as snails or crayfish in the tank to be treated. It will kill them.) Hole-in-the Head Cause: protozoan Hexamita. Symptoms: Holes appear in the head of the fish. These holes may have puss. This usually occurs in larger species of fish such as Oscars, Koi, or Pacus. Accompanying symptoms include lethargy, loss of balance, and in appetite. These symptoms and the tell-tale holes often do not appear until the condition is advanced and may at that point be untreatable. If not treated early, Hole-in-the-Head is fatal. Treatment: Jungle Hole-in-the-Head Hex-a-mit by Aquatronics, Paragon. Anchor Worm Cause: External parasites Symptoms: these parasites are visible. They are small worms that attach to the outside of the fish. They are shaped like a 'y'. These parasites are found most often in ponds or on fish that are regularly fed live foods. Other than seeing the parasite itself, there are usually no visible symptoms. Treatment: Jungle Parasite Guard Roundworms Cause: Internal parasite (nematodes) Symptoms: lethargy and inappetite. These parasites usually cannot be seen unless they are directly under the first layer of tissue. Treatment: Clout Flukes of the Skin, Gills, or Eyes Cause: Internal parasites? Symptoms: so small that they usually cannot be seen unless present on gills (this is rare to see as well). Gasping, labored breathing, scratching, flashing, darting. Treatment: Praziquantel, formalin and/or malachite green Louse Cause: external parasite Symptoms: may appear as a flat, round bump on the surface of the fish's skin. Other than that, there are usually no visible signs. Treatment: Jungle Parasite Guard or Clout. Planaria Cause: external parasite. Found in tanks with bad water quality, too much gravel, too much decaying waste in the gravel bed, and infrequent water changes. Symptoms: little white string-like worms swimming in the water. May be seen attached to the walls and decor in the tank. Treatment: Treat with Quickcure. Do 25% water changes every day for a week and remove excess gravel. Gravel should not be more than 1 1/4 inches from the bottom of the tank. For a more detailed description of Planaria and how to deal with it, click here. What are Planaria? Have you ever looked into your tank and seen tiny little white things wriggling through the water or crawling on your glass? If so, you are likely seeing Planaria. Planaria are a type of flatworm; Platyhelminthes phylum. Before you get too upset about having flatworms in your aquarium, take a deep breath. Planaria are harmless to your fish. But don't get too complacent about their presence, either. There are a few things you should be aware of . . . Why are They in My Tank? Planaria tend to crop up in aquariums where there is an excess of food and waste decaying in the gravel beds. This rotting waste is their food source. So you see, while the planaria themselves are harmless they are a symptom of a larger problem. This problem being, specifically, that uneaten food and fish waste releases ammonia as it rots. Ammonia is toxic and often lethal to fish. In a well-maintained and cycled aquarium the normal output of ammonia from uneaten food and fish waste is converted to less harmful substances by the colonies of good nitrifying bacteria built up in the tank. However, if you're seeing planaria then chances are that the problem has gone on long enough that the nitrifying bacteria is no longer present and your ammonia, nitrite, or nitrate levels are almost surely at a dangerous level now. Your fish may be experiencing health problems, behavioral changes, and ammonia poisoning at this point. As you've realized by now, planaria are warning signs that you need to re-evaluate your tank maintenance routine. How Do I Get Rid of Them and Fix My tank? The only real way to get rid of them is to remove their food source, striking at the root of the problem. To do this you'll need to do the following things: • do 15-25% water changes every day for the next week • Make sure you use a gravel vacuum when doing water changes so that you know you're getting it clean. If you never use a gravel vacuum, that's part of your problem. • You may have too much gravel in your tank. If this is the case it is providing too much space for food/waste to decay in. That makes it harder to clean during water changes and harder for the filter to suck out particles. You should never exceed 1/4 of an inch of gravel on the bottom of your tank. If you have more than that, you'll need to get rid of some. • Adding aquarium salt can help in some cases also. (Do not exceed 1 tablespoon per 5 gallons of water). However, if you keep invertibrates or scaleless fish in your tank you should skip on the salt as it can hurt or kill them. • Test you ammonia, nitrite, and nitrate levels every day to ensure that they go down and stay in safe levels. How To Make Sure They Don't Come Back If you're having planaria problems it's time to start trouble-shooting your maintenance methods. Below are some of the things you should be doing on a regular basis to keep your tank healthy and planaria-free: • • • • • weekly 25% water changes using a gravel vacuum each and every time you do water changes Don't overfeed your fish. You should only feed them as much as they can eat in 5 minutes. If you're seeing a substantial amount of food left over after they're done eating it's time to start cutting back. Test your ammonia, nitrite, and nitrate levels once a week. If you start to see you nitrates climbing (or heaven forbid, your nitrites or ammonia) you'll need to do some water changes. Make sure you don't have too much gravel. You only need 1/4 of an inch evenly spread. Bacterial Infections BACTERIA Bacteria grow erratically and are often white or milky in appearance. A bacteria infection may be localized or may be evident on several areas of the fish. Bacteria infections are likely to be found in or around open sores or any area where the fish has lost it's protective slime coating. Antibiotics and medicated food should be used to treat bacteria infections along with frequent water changes. A dirty system can prevent successful treatment. Because there are so many different types of bacteria, you may have to try several types of antibiotics before finding one that works. Be sure to do large water changes between treatments of different medications. Different resins and high-quality carbons will remove medications from the water and should be removed during any treatment with antibiotics. Internal bacterial infections may be identified by the gas they produce. This may cause the following symptoms- swelling, a fish that has trouble staying on the bottom, whitish feces that float or trail off behind the fish, or lack of feces entirely (blockage). STRESS Any system's condition that is not good for the livestock may cause stress and too much stress usually leads to disease. The most common sources of stress are: 1) Improper pH or drastic and\or sudden changes in pH. 2) Improper temperature or sudden changes in temperature. 3) Improper salinity or water density for extended periods. 4) Improper hardness, or sudden change in hardness. 5) Pounding on the system, or sudden movements that scare the fish. 6) Aggressive pond-mates. 7) Poor diet. 8) High metabolite levels. (A high nitrite level prevents oxygen from reaching the cells and may cause suffocation or brain damage). 9) High nitrate levels. (This may lower the PH as well). 10) Any measurable ammonia level. (80% of all fish waste is in the form of ammonia and is extremely toxic if not converted immediately into nitrite). 11) Other toxins. (Chlorine, copper, detergents, iron, lead, zinc, commercial ammonia, nicotine, perfume or cologne, oil, paint fumes, insecticides including contamination from dog and cat flea collars, etc.). 12) Too little or too much dissolved gas in the water, or a rapid change from water that is saturated with gases to a "normal" gas saturation level. This can be a problem when releasing newly purchased fish into the system. If the water is not mixed, the fish may suffer a condition that is very similar to "the bends" and may be just as deadly. 13) Too much or too little light. Too much light (no, or short periods of darkness), speeds up the metabolism of the fishes and does not allow the fish to rest. Too little light and the fish may be lethargic and not eat properly. 14) Dirty or cloudy water. Cloudy water is usually caused by bacteria. The bacteria in the water uses all the available oxygen and the fish suffocate. 15) No hiding places for the fish to feel safe. 16) Loss of mucous of the fish's slime coating. This condition may be caused by stress instead of the other way around, but once the slime coating is lost, additional stress is incurred. 17) Infectious (bacterial & fungal) and protozoan diseases. 18) Any other sudden changes in the environment. 19) Overcrowding. Stress triggers the release of epinephrine, a hormone which prompts the fish to get ready to fight or flee. (The hormone used to be called adrenaline.) This increases the heart rate, blood pressure and respiration. At worst continual stress will cause a fish to die of exhaustion. At best the fish's immune system may become so over-stimulated that it functions improperly and the fish dies from a disease that would not kill an unstressed organism. A over-stressed fish usually becomes sick. If the stress is severe the fish may go into shock and die immediately. Most aquatic systems have a constant supply of fungus, bacteria, and parasites that have little or no effect on a healthy fish. Once a fish is under stress however, it may fall prey to the disease organisms that comes along or are already present but that it might have resisted without being over-stressed. Fish and invertebrates are more dependent on their environment than any of the higher animals. They are totally dependent on their owners to provide them with proper living conditions. Slime Diseases Symptoms: sluggishness, frayed fins, dulled coloration (fish has bcome mucus covered), damaged gills, death There are various types of protozoa which can cause these symptoms, and they are treated in a similar way. The different parasites are Costia (Ichtybodo), Cyclochaeta (Trichodina), and Chilodonella respectively, the last being the most resistant of the parasites. Once the disease has spread to the gills, it is at its most deadly, and could prove fatal to the affected fish. remedy: The first thing to do is to contact your vet or petstore for further instruction. Several good medications are available. It is wise to treat your main tank in order to ensure that you have successfully removed all traces of the parasite from it (although it may be beneficial to also move a badly afflicted fish to a quarantine tank). Leave the filter running, but remove any activated carbon because this substance takes medicine out of the water. If the slime disease persists despite the use of a general medication, it is most likely the Chilodonella strain, and additional action must be taken. Placing your fish into a short-term bath is then suggested. NOTE that giving your fish a bath in this way is strongly discouraged except under the supervision of an expert! This said: if the fish's gills are not affected, a bath in a water-formalin solution (formalin is a corrosive poison) is suggested. If the gills are affected, the fish may not be able to survive a bath in water-formalin, and so a bath in a water-salt solution is suggested, with a water-formalin bath to follow only if the water-salt solution does not succeed. Costia Costia Latin name: Ichthyobodo necatrix, Costia necatrix Other names: Pathogen: parasite Symptoms: Flagellates 8-15 micrometers large of different form which depends on the relative position to the observer. There are two flagella on the front part of the organism, Clamped fins, Fish do swinging movements, Fish itch (fish scratch on the rocks and other objects), Fish stop feeding, Laboured breathing, Blue-grayish slime coating, Entire body covered whith gray coating, Fins stick together, Fraying of fins, Separate slightly red areas on the body, Separation of fin rays, Slime comes out of gills Scratching against hard objects, awkward swimming with fins clamped and the appearance of a velvety grayish or bluish film on the fish's body, caused by excessive slime production, is a characteristic of the disease. If the gills are badly affected, fish show signs of asphyxia, even though the oxygen level in the aquarium is normal. Gills are anemic and are covered in mucous which blocks the absorption of the dissolved oxygen. Fish will stop feeding. Sometimes fin disintegration will occur, which is characterized by the necrosis of tissues between fin rays. Denudation of fin rays is observed. Description: Costia is an invasive disease that affects many aquarium and free-living fish. It is caused by the flagellate Ichthyobodo necatrix, formerly known as Costia necatrix, a member of the Family Bodonidae, Order Protomonadina. It is very small, 8-15 micrometers in diameter. At the anterior end, the protozoan has two flagella by means of which it swims and attaches itself to the skin and gills burrowing itself into the outermost epidermal cells and feeding on their content. Microscopically, the flagellate will have different shapes (oval, cone-shaped, or curved). It is not uncommon to see four flagella ? two small and two big ones. This is explained by the parasite?s ability to multiply rapidly. The second pair of flagella will indicate that the flagellate has started dividing. In its center, the parasite has an oval nucleus. There are different vacuoles and inclusions in the protoplasm. Costia necatrix will infect the skin and gills. The parasite can only survive for a few hours without a host. Costia necatrix has a very simple life cycle. Once on the host, Costia infects the outermost epidermal cells of the skin and gills. It grows rapidly and begins to multiply by longitudinal division. It is yet unclear whether unfavorable conditions can cause the flagellate to get back to the cyst stage (encystment). It is only known that if conditions deteriorate, Costia becomes round in shape. The parasite multiplies most rapidly at temperatures of 25 to 28C (77-82F). However, it does not tolerate temperatures above 30?32C (86-89F). Outbreaks are most common in nursery tanks due to overcrowding. Adult fish rarely die of Costia, but their become carriers of disease. Clinically, chilodotiasis, trichodinosis and gyrodactylis often resemble Costia. That is why the diagnosis should be based on clinical signs of disease as well as microscopic examination of scrapings of the skin and gills. Microscopic examination is carried out with a microscope at medium power with a half-closed diaphragm. Only experts can carry out microscopic examination with a microscope at low power. How to cure: Sick fish are to be treated in a separate tank. Treat fish with a series of short-term baths: potassium permanganate solution (KMnO4), for five days sodium chloride solution (NaCI), for seven days. Artificial seawater can be used. pure copper sulfate solution (CuSO2*5H2O), daily for four days. Malachite green solution Basic violet K solution Formaline solution Bicillin-5 solution If it is impossible to treat fish in a separate tank the following medications are added into the main tank: Trypaflavine, Malachite green with copper sulfate, Rivanol, methylene blue, Bicillin-5. Water, gravel, and plants need not be taken away from the main tank after fish have been moved to the hospital tank. Without a host, parasites die within 24 hours. As a preventive measure, water temperatures can be raised to 32?34C (90-93F) for two days. Once the treatment is over, fish are reintroduced into the aquarium and are given large amounts of fresh feed. Medicine: SERA Costapur Sera Ectopur TetraMedica ContraIck TetraMedica General Tonic Aquarium Pharmaceuticals General Cure Aquarium Pharmaceuticals All-Natural Melafix Potassium permanganate solution sodium chloride Pure copper sulfate solution Malachite green solution Basic violet K solution Formaline solution Bicillin-5 solution Prevention: Newly bought fish are quarantined for 30 days. Before introducing new fish into the aquarium, give them three short-tem therapeutic baths. Do not let water from the tank get into live feed. It is not advisable to introduce pond plants without first disinfecting them. Nets, scrapers, feed boxes, thermometers, pulverizers and other equipment should not be shared between several aquaria. TRICHODINA (Cyclochaeta) Another protozoan parasite, this one resembles a flying saucer in shape and behaviour, spinning and dancing as it does it is very easy to identify using a microscope with a 100 x or greater .. this parasite is normally found when water temperatures are high and causes excessive mucus secretion and blemishes on the skin and gill surfaces - this parasite affects the respiration which eventually weakens the koi. Method of Eradication:- Potassium Permanganate Crystals. Method: Measure Potassium Permangante crystals at the rate of 1.5 grams per ton (220 gallons) of water. Mix in a clean plastic bucket with water close to the boiling point and pour over the crystals, ensuring that all the crystals are dissolved - then leave this to stand for at least 30 minutes until the water cools down. Before application stir thoroughly once more and then pour the solution round the perimeter of the pond - this will turn the water a violet colour but after a few hours will begin to clear. A second doseage may be required if the water temperature is above 68 degrees F, after 7 days. Probably the most common of the Parasites that invade our Koi are:- Trichodina a common fish parasite Written by Frank Prince-Iles FishDoc Extremely irritating It is not uncommon to find small populations of the parasite Trichodina on fish. At low levels they don't pose a threat to fish health. Unlike many parasites it doesn't actually feed on fish; these parasites only use the fish host as a home and means of transport! However, in large numbers they are extremely irritating and it is likely that some tissue damage will result from the sucking disc that trichodinids use for attachment. Healthy fish can control the numbers of parasites. Severe trichodinid infestations are usually associated with overcrowding and poor water quality. Under such conditions these parasites can rapidly multiply. Trichodina This shows the outer rim of cilia and the central sucking disc with its hook-like denticles Trichodina in a wet mount (mucus) at low magnification Trichodina on the edge of a gill filament. Note the density, with some sitting on top of others. Identification They are easy to recognize in a wet mount. They always remind me of flying saucers, hovering and skimming over the surface of the gill or skin. They are top-hat shaped when viewed from the side. When viewed from the top it is possible to see an outer ring of cilia and the concentric rings and hook-like denticles of the sucking disc. (See the top photo) Gill trichodinids are smaller than their skin-dwelling cousins, usually less than 30 mm. They also tend to move faster than skin trichodinids. Those found on the skin are usually > 50 mm. The fish react to Trichodina in much the same way as any other parasite by rubbing and flashing. There may be focal areas of reddening. At a later stage the fish will be lethargic, they may isolate themselves, stop feeding and lay on the bottom with clamped fins. While they are not as immediately life-threatening as most parasites, heavy infestations do cause considerable stress to the fish and it is not uncommon for other ectoparasites and bacteria to take advantage leading to secondary infections. Treatments My own experience is that this parasite can be tricky to treat. Sometimes it responds to proprietary parasite treatments and other times they have little or no effect. The same applies to malachite green and formalin. The most effective treatment against Trichodina seems to be potassium permanganate which seems to work virtually every time. Usually only one treatment is needed to. Salt baths can be useful if only dealing with just one or two fish. Article and pictures placed here with permission from the author, Frank Prince-Iles FishDoc http://www.fishdoc.co.uk It’s the joint action of the Denticles and the cilia that irritate as they rasp on the skin surface of the koi, causing the koi to flash off the pond bottom in an attempt to shake this parasite off. This is usually accompanied by an increase in mucus production. Although Trichodina are not readily associated with mortalities of koi on there own, except when in great numbers on the gill lamellae, the blade like Denticles are the prime way the koi gets infections as the epidermis is breached by the rasping action of the Denticles, secondary bacterial infections often occur at the site of such a breach in the epidermis Another way Trichodina damages koi indirectly, is by irritating the koi to such a point, that in an attempt to shed the parasite it can and does damage itself on objects in the pond yet again secondary infection can occur. As stated the underside is concave with the Denticles hanging down and this is the side presented to the koi’s skin, the other side is convex and is the side looking away from the koi’s skin, this is the side where the mouth and the gullet is located, so the feeding side of this parasite is away from the koi’s body. Trichodina reproduce by binary fission or division and for this reason treatment becomes that much easier, as a typical successful treatment gets all generations of this parasite usually in one treatment. CHILONONELLA: Chilodonella - this is the one parasite that kills so many fish so fast in the Springtime. Chilodinella is one of the hottest fish killers there is. Under the scope you may see a heartshaped organism, or a large round organism full of tiny bubbles. Alive, the chilodinella resembles a heart shaped onion, with a fuzzy end where you could imagine the onions roots would be. These are actually cilia. Dead, Chilodinella are motionless round balls full of tiny bubbles. They may resemble Ich but they do not have a crescent nucleus nor do they move in their dead, rounded state. Chilodinella clears EASILY with salt. Leave the salt in for 14 days, and be sure to supplement aeration, as gill damage d/t Chilodinella may be severe in the survivors. Chilodinella should be suspected anytime large numbers of fish are dying on the surface, or who roll over on their sides except when disturbed, the Koi dash madly. http://media.putfile.com/3D-Chilo Method of Erradication: Treats easily with salt at the doseage rate of 3/4 ounce per gallon (0.75 percent). Clears almost overnight, so immediate salting can save a lot of fish. Treatments: 1.5% on up to 3% salt dips and placing into a sterile environment, then continue with QuickCure continuously for 3 days. This can be a harsh treatment so follow instructions carefully, aerate very well and have a fresh tub of water on standby. This treatment can be a sure fire kill if done correctly. Potassium permanganate bath and placing into sterile environment. Scope and treat one more time if the fish's health allows or need be. Other treatments such as Parasite clear and a 0.3% salt solution, along with salt dips, can be quite successful. It took 2 weeks at 0.8% (not a typo) salinity and 3 PP dips @ 2ppm for 4 hours, once every 3 days, to kill off an especially hardy strain of Chilodonella (?Uncinata?) once and for good. All of the rest of the treatments listed above failed, multiple times. BLACK SPOT Symptoms: Small black speckles on body Flickering Small black smudges on fish Scratching against surfaces Very irritated Symptoms of Stress & Disease Black Spot General Description A disease caused by the larvae of parasitic digenetic flukes, Cercaria and Metacercaria. A common disease in earthen bottom ponds and lakes, this disease is caused by a parasite (larval trematode) that burrows into the skin of a fish causing the formation of a cyst approximately one millimeter in diameter. This parasite has a complex life cycle that requires fish eating birds or mammals, snails, and fish at different stages in order to survive. In general, even heavy infestations of these parasites do relatively little damage to the fish. There is some evidence that heavily infested juvenile fish may experience excessive blood loss, physiological stress, and even death. Also, fish with heavy infestations on the eyes may be blinded. The term "Black Spot" refers to the formation of small cysts in the muscle and skin around which the parasite lives. The cyst accumulates black pigment cells. These cause little harm to the fish. Young fish have growth problems if heavily infected. The first intermediate host is a mollusc. The fish is the second intermediate host and the final host is a kingfisher or heron. Black Spot Treatments Black spot is generally easy to cure. There are a number of commercially available treatments and preventatives. Black Spot Prevention Be careful when adding new fish. Black Spot, or diplopstomiasis, often follows the addition of new aquarium fish. All fish are susceptible, especially the Silver Dollar and Piranha. It is fairly easy to diagnose and treat. Fish Diagnosis Chart Appearance Symptoms Possible Causes Treatments Black spots appearing Caustic irritant Parasites Test and correct water Parasite treatment Broken spines on fins Mechanical damage Will heal without treatment Color change; white spreading Pigment loss to the skin Not a problem if fish is acting good, eating well, and fins look OK Can be caused by a temperature spike Crooked ("S"-shaped) back Malnutrition -- lack of vitamin C Enlarged ovary Add good-quality food No action required Mechanical damage Dropping scales Myxosporidia protozoans Water accumulation Eyes bulging Trauma to the eye Will heal without treatment Is not treatable; change water If related to Dropsy, can be fatal Will return to normal shortly Exothalamus Bacterial infection; no cure, but not fatal Eyes pop out Edwardsiella Etarda Bacterial infection carried by frogs & turtles Feed Romet B Inject Chloramphenicol or Amakacin Fins or tails are eaten away; red area adjacent to body Fin/Tail Rot Jungle Fungus Eliminator Salt solution Antibiotics Gills are bright red No problem No action required Gills are brownish Nitrite toxicity Correct water chemistry Gills are dark red Water quality problem Test & correct water quality Gills are light red with patches of rotten tissue Bacterial infection Salt solution Antibiotics Jungle BGDX Eye/eyes pop out Gills swollen open or pale red Gill cover has hole Milky skin Flukes Tuberculosis Aeromonas bacteria Excess mucus production pH plunges Ammonia burn Parasites Parasite treatment TB not treatable Antibiotics Raise water temp to 85 deg F Test and correct water Salt Parasite treatment Mouth rotting away Parasite caused the initial lesion; Flukes Formalin Antibiotics Red belly Aeromonas infection Bacterial infection Antibiotics Injections Raise water temp to 85 deg F Red mouth Columnaris infection or Enteric redmouth Romet B antibiotic food Red spiderweb under scales Stress Bad water quality Parasites Test and correct water Salt Treat for parasites Red spots on skin Bacterial infection Abrasions Parasites (Flukes) Antibiotics Salt Parasite treatment Red streaks on fins and/or tail near body Hemorrhagic Septicemia Jungle Fungus Eliminator Clear Pond Treats All Nearly always fatal Scales are white or clear Site of wound which has healed No action required Scales missing on a "fat" fish Mating ritual Treat for parasites & then bacteria Salt dip Peroxide on wound Neosporin Creme on wound Anotbiotics Scales stand out on part of the body Mating Parasites Test and correct water Salt Slimy, light-colored feces with bubbles Constipation No food for 2 days, then chopped earthworms for 3 days Split fin Flukes Parasite treatment Suture fin Swollen abdomen; no raised scales Fatty liver Egg impaction Cystic kidneys Swollen and deformed abdomen; no raised scales Cancer of some kind Cystic kidneys Surgery Swollen abdomen; raised scales all over body Dropsy Jungle Fungus Eliminator Heat water to 85 deg F Add 1/8 tsp Epsom Salt to 5 gallons water Antibiotic food Usually fatal Ulcers, lethargy, & loss of appetite Bacterial infection Aeromonas/Pseudomo nas Salt Antibiotics Raise water temp to 85 deg F Very red fins Stress Nitrate poisoning Ammonia or Nitrite Parasites Bacterial sepsis Test and correct water Salt Parasite treatment Wasting away Flukes (smaller fish) TB of the liver (larger fish) Remove eggs Parasite treatment Flexobacterial infection Corneal edema Caustic trauma White eye Antibiotics Time will heal Caused by Formalin or Ammonia Aeromonas bacteria White ring around red ulcer Antibiotics Raise water temp to 85 deg F Behavior Symptoms Anorexia, excess slime, isolation, resting on the bottom, streaking of the fins, and finally death Clamped fins Fins collapsed close to body; listless behavior Flashing/scratching Possible Causes Treatments Acidosis Water changes Buffering agent pH crash Parasites Test and correct water Salt Parasite treatment Gill Flukes Jungle Parasite Guard Anti-parasite food Sulfadimethoxin Parasites Changes in water quality UV stabilizers in PVC pipe Specific parasite treatment Test and correct water Don't use untested plastics Gasping at the surface Inadequate oxygen in water Gills are damaged Test and correct water Salt Gasping at the surface; excess slime; death Alkalosis Water changes Buffering agent Hover at the surface; milky skin pH plunge Test and correct water Salt Isolate themselves, lie on the bottom, clamp their fins, secrete excess slime Ammonia toxicity Water changes Manage pH Aeration Jumping Irritant in the water Flukes Test and correct water Parasite treatment Salt Potassium Permanganate Jumping; small lump on skin or fins Fish Lice (Argulus) Jungle Parasite Guard Labored breathing and eratic movements Salt Toxicity Reduce salt concentration in water Lethargic; don't play Inadequate aeration Add waterfall, venturi, or air stone Laying inactive on bottom; gills are light red Bacterial Gill Disease Parasites Jungle BGDX Salt Open gills, rapid respiration Gill Flukes Jungle Parasite Guard Rolling/spiral swimming Neurological disorder due to poison >50% water change Chloramine and heavy metal neutralizer Rubbing objects and breathing rapidly Acidosis Correct pH of water Scratching on bottom or objects in pond Itching Jungle Parasite Guard Clear Pond Treats All Sitting on bottom; struggle to swim to surface Swim bladder problem (bacteria) Electrocution Antibiotics Salt GFCI outlet Sitting on bottom: swim fine when disturbed Heavy Fluke infection Fluke Tabs Salt Spitting Normal behavior Fluke infestation No problem Fluke Tabs Swimming VERY fast Bad water quality Test and correct water Swimming with head down, tail up at the surface Bacterial infection Antibiotic injections Swimming with mouth open; can't close it Foreign body stuck in the mouth Ulcer or sore in the roof of the mouth Remove object through the gill Swab with hydrogen peroxide Swimming with tail up Swim Bladder Disorder Jungle Fumgus Eliminator Constipated No food for 2 days, then chopped earthworms for 3 days Feed more green roughage Swimming upside down External Problems Symptoms Possib le Cause s Treatments Golden velvety coating on the back of the fish Velvet Diseas e Acriflavine Leeches Leech Salt solution Small lump on skin or fins; jumping Fish Lice (Argul us) Jungle Parasite Guard Small thread-like worms attached to the body of the fish Ancho r Worm Trichlorfon Potassium Permanganate Jungle Parasite Guard Mecurochrome swab Dimilin Waxy growth on skin and fins Fish Pox Viral infection Heat water to 85 deg F Salt White cottony growth on body or fin (like goblets) Epistyl is Salt White Fungu s Jungle Fungus Eliminator Salt Peroxide Potassium Permanganate Colum naris bacteri a Salt Potassium permanganate Antibiotic food Swab peroxide and Neosporin on the wound Staph infecti on Salt Potassium permanganate Antibiotic food Swab peroxide on the wound White Spot or Ick Salt > 1 ppt Malachite Green Clear Pond Treats All Methyl Blue Copper salts Raise water temp to 85 deg F White cottony growth on body or fin (like strands of hair) White cottony growth on body or fin; red around the wound; darkened skin; loss of slime coat; can go systemic White cottony growth on body or fin; very dark red around the wound; usually an Oranda White pinhead spots on body or fins Feeding Problems Symptoms Possible Causes Treatments Loss of appetite; surfacing pH crash Test and correct water; add buffer to water Loss of appetite, ulcers, & lethargy Bacterial infection Antibiotics