Programme - International Conference on Brain Monitoring and
Transcription
Programme - International Conference on Brain Monitoring and
Welcome Dear Colleagues and Friends, We are delighted to welcome you to Cork, Ireland for the 9 th International Conference on Brain Monitoring and Neuroprotection in the Newborn. This meeting would not be possible without the involvement and support of the Faculty. We would like to thank them for their encouragement and assistance in the development of the conference programme. We look forward to a wonderful programme of workshops and we are very pleased that over 250 delegates are in attendance from so many countries. We look forward to sharing knowledge and expertise throughout this stimulating and interesting conference. This conference is accredited by the European Accreditation Council for Continuing Medical Education (EACCME) and is designated for a maximum of 15 hours of European external CME credits. Certificates of accreditation will be emailed to you after the conference. *Please note: Credits received will be based on your registered attendance. Also we would like to acknowledge Abbey Conferences for their efforts in organizing the conference. We hope you enjoy! Céad míle fáilte, Geraldine Boylan and Robert White Conference Co-Chairs 3: Conference Co-Chairs Geraldine Boylan is Professor of Neonatal Physiology, Department of Paediatrics & Child Health, University College Cork, Ireland and Director of the Irish Centre for Fetal and Neonatal Translational Research. - www.infantcentre.ie Robert White is the American Academy of Pediatrics representative to and co-chair of the AAMI Committee on Incubators, the US representative to the International Electrotechnical Equipment Working Group for Paediatric Equipment, and a member of the Healthcare Guidelines Revision Committee. 4: Scientific Subcommittee Mona Toet trained as a paediatrician and neonatologist in the Wilhelmina Children’s Hospital in Utrecht, The Netherlands. She has worked as a neonatologist in Utrecht since 1996. Linda de Vries trained as a paediatrician and neonatologist in the Wilhelmina Children’s Hospital in Utrecht, The Netherlands. Since 1989, she has worked in the department of Neonatology in Utrecht, where she is Professor in Neonatal Neurology since 2001. Lena Hellström-Westas, MD, PhD, is Professor of Perinatal Medicine at Uppsala University, and Senior Consultant in Neonatology at the Department of Neonatology, Uppsala University Hospital, Sweden. 5: Faculty Nicholas Abend is an Assistant Professor of Neurology and Paediatrics at the Children’s Hospital of Philadelphia and the Perelman School of Medicine, University of Pennsylvania, USA. Kurt Albertine is Professor of Paediatrics, Adjunct Professor of Internal Medicine, and Adjunct Professor of Neurobiology & Anatomy, University of Utah, USA. John Barks, M.D. is a Professor of Paediatrics and Communicable Diseases at the University of Michigan, and the Director of the Division of Neonatal-Perinatal Medicine at University of Michigan’s C.S. Mott Children’s Hospital, USA. Frank van Bel MD, PhD, is Professor in Neonatology, at University of Utrecht, and Consultant Neonatologist at University Medical Center, Wilhelmina Children’s Hospital, Utrecht, The Netherlands. 6: Faculty Manon Benders qualified in 2006, and is a consultant neonatologist in Wilhelmina Children’s Hospital, University Medical Center, Utrecht, The Netherlands. Robert Clancy is Professor of Neurology and Paediatrics at the Perelman School of Medicine, University of Pennsylvania, USA. He is founder of the Paediatric Regional Epilepsy Program of the Children’s Hospital of Philadelphia, USA. Eugene Dempsey is a Consultant Neonatologist at Cork University Maternity Hospital and Clinical Professor of Paediatrics in the Department of Paediatrics and Child Health, University College Cork, Ireland. Alistair Gunn is Professor 0f Physiology and Paediatrics, and a Paediatrician-scientist in the Department of Physiology at the University of Auckland, New Zealand. 7: Faculty John Hartline is the Editor-in-Chief of NeoReviewsPlus©,a neonatologist and a member of the NeonatalPerinatal Section of the American Academy of Pediatrics (AAP), USA. Terrie Inder is Chair of the Department of Paediatric & Newborn Medicine, and Mary Ellen Avery Professor in Paediatrics in the Field of Newborn Medicine at Brigham & Women's Hospital Boston, USA. Petra Lemmers is consultant neonatologist at the Wilhelmina Children’s Hospital/University Medical Center, Utrecht, The Netherlands. Solomon Moshé, is the Charles Frost Chair in Neurosurgery and Neurology, and Professor of Neurology, Neuroscience and Paediatrics at Albert Einstein College of Medicine, The Bronx, New York, USA. 8: Faculty Jeffrey Neil is a practicing paediatric neurologist specialising in neonatal neurology and Professor of Neurology at Boston Children’s Hospital, Boston, Massachusetts, USA. Gunnar Naulaers is a Consultant Neonatologist, and Head of the NICU at University Hospital Leuven and is Associate Professor at Katholieke Universiteit Leuven, Belgium. Ronit Pressler is a Consultant in Clinical Neurophysiology and clinical lead of the Telemetry Unit at Great Ormond Street Hospital, London and Honorary Senior Lecturer at the UCLInstitute of Child Health, London, UK. Janet Rennie is Consultant Neonatologist at University College London Hospital and part of the Research Department of Neonatology at UCL EGA Institute for Women's Health, London, UK. 9: Faculty Ingmar Rosén Professor emeritus of Clinical Neurophysiology Lund University. and since 1986 Head physician at the Department of Clinical Neurophysiology, University Hospital, Lund. Renée Shellhaas, MD, MS is Clinical Associate Professor of Paediatrics (Neurology Division) at the University of Michigan, in Ann Arbor, MI, USA. Sampsa Vanhatalo is Head of Paediatric Neurophysiology at Helsinki University Hospital. He is currently Clinical Research Fellow of Finnish Academy, based in Helsinki University Central Hospital, Finland. Courtney Wusthoff currently serves as the neurology director for the Lucile Packard Children’s Hospital Neuro/Neonatal ICU and is Assistant Professor of Neurology and Paediatrics at Stanford University, USA. 10: Programme Wednesday 30th September 2015 17.00- 19.00 Registration/Conference Desk Open Hotel Lobby 17.00-19.00 Poster set-up Preconference Area 15.00-18.00 Exhibitor set-up Exhibit Area Thursday 1st October 2015 (Workshops) Workshop A Workshop C.1 Workshop D.1 Workshop E Workshop F (Single session) (Single session) (Single session) (Double session) (Double session) Industry Sponsored Dr Mahony Room The Cove Interpreting MRI in the the Neonatal term neonate EEG Robert Clancy, Ronit Pressler Terri Inder, Linda de Vries 10.00-10.30 The Boardroom MRI in the preterm neonate NIRSmonitored brain oxygenation Frank van Bel, Petra Lemmers, Gunnar Naulears Tea/Coffee The Cove Interpreting MRI in the the Neonatal term neonate EEG Robert Clancy, Ronit Pressler aEEG for the Experienced User Lena HellströmManon Benders, Westas, Jeffrey Neil Mona Toet Workshop B Workshop C.2 Workshop D.2 (Single session) (Single session) (Single session) Industry Sponsored Dr Mahony Room Industry Sponsored Industry Sponsored Fleming Room Smith Barry Suite Terri Inder, Linda de Vries The Boardroom MRI in the preterm neonate Workshop E (Continued) Workshop F (Continued) Industry Sponsored Industry Sponsored Fleming Room Smith Barry Suite aEEG for the Experienced User Lena HellströmManon Benders, Westas, Jeffrey Neil Mona Toet NIRSmonitored brain oxygenation Frank van Bel, Petra Lemmers, Gunnar Naulears 11: Programme Thursday 1st October 2015 (Conference) 08.00-18.00 Registration/Conference Desk Open Hotel Lobby 12.00 – 13.00 Lunch Exhibit Area Hotel conference room 13.00–15.10 Session 1 Electrophysiology 13.00-13.10 Welcome – by conference co-chairs Geraldine Boylan and Robert White 13.10-13.50 Seizure mechanisms in the developing brain Solomon Moshé 13.50-14.30 New directions in the neonatal EEG analysis Sampsa Vanhatalo 14.30-15.10 aEEG/EEG applications in the NICU Lena HellströmWestas 15.10-15.30 Tea/Coffee Exhibit Area 15.30-18.00 Session 2-Neonatal Seizures Hotel conference room 15.30-16.10 Metrics of Neonatal Seizure Quantification Robert Clancy 16.10-16.50 Detecting electrographic seizures in the preterm infant; aEEG or EEG? Courtney Wusthoff 16.50-17.30 Neonatal seizure trials: promise or peril? Ronit Pressler 17.30- 18.00 Panel Discussion Chaired by Ingmar Rosén 18.00 Finish 19.30 Welcome Reception and Buffet 12: Fota Clubhouse Programme Friday 2nd October 2015 08.00-18.00 Registration/Conference Desk Open 08.30-10.30 Session 3- Neuroprotection 08.30-09.10 Early brain activity and brain growth 09.10-09.50 09.50-10.30 Contribution of inflammatory mediators, oxidants and antioxidants on brain injury in neonates Can we improve therapeutic hypothermia? Some preclinical evidence 10.30-11.00 Tea/Coffee 11.00-12.20 Session 3- Neuroprotection Hotel Lobby Hotel conference room Manon Benders Kurt Albertine Alistair Gunn Exhibit Area Hotel conference room 11.00-11.40 Next generation cooling trials John Barks 11.40-12.20 Seizures and EEG Monitoring Beyond the Neonatal Period Nicholas Abend 12.20-14.00 Lunch and Poster Presentations 14.00-16.05 Session 5- Neuromonitoring 14.00-14.40 Sleep in the NICU – what have we been missing? Exhibit Area Hotel conference room Renée Shellhaas 13: 14.40-15.20 Abstract presentations 14.40-14.55 Functional brain connectivity in the newborn develops rapidly, changes between sleep states, and is affected by fetal drug exposure Anton Tokariev 14.55-15.10 Diffuse Optical Imaging of Resting State Functional Connectivity In Newborns Chuen Wai Lee 15.10-15.25 Early electrographic seizure activity in preterm infants < 32 weeks gestation. Rhodri Lloyd 15.25-16.05 Clinical application of NIRS monitoring Frank van Bel 16.05-16.20 Tea/Coffee 16.20-18.00 Session 6- Neuromonitoring Exhibit Area Hotel conference room 16.20-17.20 Abstract presentations 16.20-16.35 EEG Predicts Delayed Maturation on MRI at Term in Preterm Infants. Chikako Ogawa 16.35-16.50 Effect of propofol on cerebral hemodynamic parameters and amplitude integrated EEG in newborns. Liesbeth Thewissen 16.50-17.05 Lidocaine efficacy in aEEG-confirmed neonatal seizures: retrospective study of 413 full-term and preterm infants Lauren Weeke 17.05-17.20 Early statistical measures of EEG bursts indicate clinical outcomes in extremely preterm infants Kartik Iyer 17.20- 18.00 Monitoring the newborn brain – which technique for which question? Terrie Inder 18.00 14: Finish Programme Saturday 3rd October 2015 08.00-13.00 Registration/Conference Desk Open Hotel Lobby 11.00-> Poster take down Preconference Area 11.00 -> Exhibitor take down Exhibit Area 08.30-10.35 Session 7-Topics of general interest 08.30-09.10 Neuromonitoring in the delivery room Eugene Dempsey 09.10-09.50 Imaging biomarkers – will they ever be ready for the rest of us? Jeffrey Neil 09.50-10.35 Abstract presentations 09.50-10.05 10.05- 10.20 Regional cerebral oxygenation as measured by NIRS is related to neurodevelopmental outcome at 2 years of age Untargeted metabolomic analysis and pathway discovery in perinatal asphyxia and hypoxic ischaemic encephalopathy 10.20-10.35 Cerebral oxygen metabolism varies across neonatal sleep-wake states 10.35-11.00 Tea/Coffee 11.00-13.30 Session 8-Topics of general interest 11.00-11.40 11.40-12.00 Learning from reflection, complex clinical cases (with ARS) Update: The role of MRI in neonatal seizures Hotel conference room Thomas Alderliesten Niamh Denihan Renée Shellhaas Exhibit Area Hotel conference room Janet Rennie Linda de Vries 15: 12.00-12.20 Update: Out with the old and in with the new? Effect of NICU environment Gunnar Naulaers 12.20-13.00 ARS – open questions from the audience John Hartline and Robert White 13.00-13.15 Oral and Poster Prize giving 13.15 – 13.30 Closing address Robert White and Geraldine Boylan 13.30 Finish 13.30 Take away Lunch 16: Exhibit Area Oral Abstract Presentations Functional brain connectivity in the newborn develops rapidly, changes between sleep states, and is affected by fetal drug exposure Anton Tokariev1,2,4, Mari Videman3,4, Susanna Stjerna1,4, Eija Gaily3, Matias Palva2, Sampsa Vanhatalo1,3,4 1 Department of Clinical Neurophysiology, HUS Medical Imaging Center, Helsinki University Central Hospital and University of Helsinki, Finland 2 Neuroscience Center, University of Helsinki, Finland 3 Department of Pediatrics, University of Helsinki, Children’s Hospital, Helsinki University Central Hospital, Finland 4 BABA center, Children’s Hospital, Helsinki University Central Hospital, Finland Diffuse Optical Imaging of Resting State Functional Connectivity In Newborns Chuen Wai Lee1,2, Rob Cooper1,3, Laura Dempsey1,3, Maria Chalia1,2, Sabrina Brigadoi1,3, Jem Hebden1,3, Topun Austin1,2 1 neoLAB, The Evelyn Perinatal Imaging Centre, Cambridge University Hospitals NHS Foundation Trust, UK Department of Neonatology, Cambridge University Hospitals, NHS Foundation Trust, UK 3 Department of Medical Physics and Biomedical Engineering, University College London, UK 2 Early electrographic seizure activity in preterm infants less than 32 weeks gestation. Rhodri Lloyd 1,2, John O'Toole 1, Peter Filan 1,2, Geraldine B Boylan 1,2 1 2 INFANT: Irish Centre for Fetal and Neonatal Translational Research, University College Cork, Ireland Department of Neonatology, Cork Univeristy Maternity Hospital, Ireland EEG Predicts Delayed Maturation on MRI at Term in Preterm Infants. Chikako Ogawa1, Hiroyuki Kidokoro1, YujiIto1, Tamiko Negoro1, Kazuyoshi Watanabe1, Yuichiro Sugiyama2, Miharu Ito2, Yoshiaki Sato2, Masahiro Hayakawa2, Jun Natsume1 1 2 Department of Pediatrics, Nagoya University Graduate School of Medicine, Japan Center for Maternal-Neonatal Care, Nagoya University Hospital, Japan Effect of propofol on cerebral hemodynamic parameters and amplitude integrated EEG in newborns. Thewissen L 1, Smits A 2, Caicedo A 3 , Koolen N 3, Allegaert K 1 , Naulaers G 1 1 Department of Neonatology, University Hospitals, Leuven of Pediatrics, University Hospitals, Leuven 3 Department of Electrical Engineering, STADIUS-ESAT, KU Leuven 2 Department 17: Lidocaine efficacy in aEEG-confirmed neonatal seizures: retrospective study of 413 full-term and preterm infants Lauren Weeke 1, Linda van Rooij 1, Mona Toet 1, Floris Groenendaal 1, Geraldine Boylan 2, Ronit Pressler 3, Marcel van den Broek 4, Linda de Vries 1 1 Department of Neonatology, Wilhelmina Children’s Hospital, University Medical Centre Utrecht, The Netherlands 2 Irish Centre for Fetal and Neonatal Translational Research, University College Cork, Ireland 3 Section of Clinical Neurosciences and Neonatal Unit, University College London, London, UK 4 Department of Clinical Pharmacy, University Medical Centre Utrecht, Utrecht, The Netherlands Early statistical measures of EEG bursts indicate clinical outcomes in extremely preterm infants Kartik Iyer 1, James Roberts 1, Lena Hellström-Westas 2, Sverre Wikström 3, Ingrid Hansen Pupp 4, David Ley 4, Sampsa Vanhatalo 5, Michael Breakspear 1 1 QIMR Berghofer Medical Research Institute, Australia of Women’s and Children’s Health, Uppsala University, Sweden 3 Centre for Clinical Research, Karlstad Central Hospital, Sweden 4 Department of Pediatric, Institute for Clinical Sciences, Lund University, Sweden 5 Department of Pediatrics, Children’s Hospital, University Central Hospital and University of Helsinki, 2 Department Regional cerebral oxygenation as measured by Near-InfraRed Spectroscopy (NIRS) is related to neurodevelopmental outcome at 2 years of age Thomas Alderliesten, Ingrid van Haastert, WimBaerts, Niek van der Aa, Linda de Vries, Corine Koopman-Esseboom, Frank van Bel,Petra Lemmers University Medical Center Utrecht, Wilhelmina Children's Hospital, Utrecht, The Netherlands Untargeted metabolomic analysis and pathway discovery in perinatal asphyxia and hypoxic ischaemic encephalopathy Niamh M Denihan1, Jennifer A Kirwan2, Brian H Walsh3, Warwick B Dunn2, David I Broadhurst 4, Geraldine B Boylan 1, Deirdre M Murray 1 1 Neonatal Brain Research Group and Irish Centre for Fetal and Neonatal Translational Research, University College Cork, Ireland 2 School of Biosciences, University of Birmingham, UK 3 Division of Newborn Medicine, Boston Children's Hospital and Department of Pediatric Newborn Medicine, Brigham and Women's Hospital, Boston, USA 4 Department of Medicine, University of Alberta, Canada Cerebral oxygen metabolism varies across neonatal sleep-wake states Renee Shellhaas 1, Joseph Burns 2, Ronald Chervin 3, John Barks 1 1 University of Michigan Department of Pediatrics & Communicable Diseases, United States Tech Research Institute, United States 3 University of Michigan Department of Neurology, United States 2 Michigan 18: Poster Presentations Theme 1 - Progression of, and influences on, fetal or neonatal brain development, both normal and abnormal 1. Data-driven method for tracking early EEG maturation Ninah Koolen 1,2, Anneleen Dereymaeker 3, Okko Räsänen 4, Susanna Stjerna 5, Katrien Jansen 3, Jan Vervsich 3, Vladimir Matic 1,2, Maarten De Vos 6, Gunnar Naulaers 3 , Sabine Van Huffel 1,2, Sampsa Vanhatalo 5, 1 Division STADIUS, Department of Electrical Engineering (ESAT), University of Leuven, Belgium iMinds-KU Leuven Medical IT Department, Belgium 3 Department of Development and Regeneration, Neonatology, University of Leuven, Belgium 4 Department of Signal Processing and Acoustics, Aalto University, Finland 5 BABA center and Department of Children’s Clinical Neurophysiology, HUS Medical Imaging Center and Children’s Hospital, Helsinki University Central Hospital, University of Helsinki, Finland 6 The Institute of Biomedical Engineering,Department of Engineering Science, University of Oxford, UK 2 2. Effects of prenatal serotonin reuptake inhibitor exposure on newborn brain activity Mari Videman 1, Anton Tokariev 2,3, Sampsa Vanhatalo 3, 1 Department of Pediatric Neurology, Helsinki University Hospital, Finland Department of Biosciences, University of Helsinki, Finland 3 Department of Children's Clinical Neurophysiology, Medical Imaging Center and Children's Hospital, Helsinki University Hospital and University of Helsinki, Finland 2 3. Clinical characteristics and neurodevelopmental outcomes of preterm infants with punctate white matter lesions: from the viewpoint of neonatologists. Ken Imai, Atsushi Uchiyama, Eri Sugita, Satsuki Totsu, Hidehiko Nakanishi, Satoshi Kusuda , Department of Neonatology, Tokyo Women's Medical University, Japan 4. Concurrent EEG and SEP recording in the NICU: a possible and useful strategy in early assessment of newborns after HIE. Viviana Marchi 1, Päivi Nevalainen 2, Marjo Metsäranta 3, Sampsa Vanhatalo 2, Leena Lauronen 2, 1 Department of Developmental Neuroscience, Stella Maris Scientific Institute, IRCCS Stella Maris Foundation Pisa, Italy; Department of Clinical and Experimental Medicine, University of Pisa, Italy 2 Department of Clinical Neurophysiology, Children's Hospital, HUS Medical Imaging Center, HUCH, University of Helsinki, Finland 3 Department of Neonatology, Children's Hospital, HUCH, Finland 19: 5. Brain-Injury After Neonatal Surgery For Non-Cardiac Congenital Anomalies Lisanne Stolwijk 1, Petra Lemmers 1, Kristin Keunen 1, Floris Groenendaal 1, Maud van Herwaarden2, Frank van Bel1, David van der Zee2, Linda de Vries1, Manon Benders1, 1 Neonatology, Wilhelmina's Children Hospital, University Medical Center Utrecht, The Netherlands Surgery, Wilhelmina's Children Hospital, University Medical Center Utrecht, The Netherlands 2 Pediatric 6. Developmental expression patterns of KCC 2 and functionally-associated molecules in the human brain Kai Kaila 1, Goran Sedmak 2, Nataša Jovanov-Milošević 2, Monika Ulamec 3, Božo Krušlin 3, Martin Puskarjov 1, Miloš Judaš 2, 1 University of Helsinki, Department of Biosciences and Neuroscience Center, Finland University of Zagreb School of Medicine, Croatian Institute for Brain Research, Croatia 3 University of Zagreb School of Medicine, Clinical Hospital Center Sisters of Mercy, Department of Pathology, Croatia 2 7. Relationship between General Movements and neuroimaging findings in infants with high risk for brain injury: a pilot study Renato Gasperini , Gabriel Variane , Rodrigo Figueredo, Francisco Rodrigues , Heitor Castelo Branco Rodrigues Alves, Maurício Magalhães , Santa Casa De São Paulo - SP Brazil, Brazil 8. Automated neonatal brain volumetric analysis in Down syndrome. K Murphy 1, JA Allen 2, RS O'Neill 2, CO Bogue 3, PM Filan 2, 1 Irish Centre for Fetal and Neonatal Translational Research, University College Cork, Ireland Department of Neonatology, Cork University Maternity Hospital, Ireland 3 Department of Radiology, Cork University Hospital, Ireland 2 9. Risk Factors For Cerebral Hemorrhage In Preterm Infants ≤32 Weeks Gestational Age Maria Livia Ognean 1, Oana Boanta 1, Ecaterina Olariu 1, Simona Kovacs 2, Doina Andreicut 2, 1 Neonatology 2 Dpt., Clinical County Emergency Hospital, Romania Premature Infants' Dpt., Clinical County Emergency Hospital, Romania 20: 10. Potential neuroprotective effect of miR-374a downregulation in hypoxic ischaemic encephalopathy. Ann-Marie Looney1, Shane Hegarty3, Katie Togher2,3, Gerard O'Keeffe2,3, Deirdre Murray1, 1 Irish Centre for Fetal and Neonatal Translational Research,University College Cork, Ireland Dept of Anatomy and Neuroscience, University College Cork, Ireland 3 Dept of Obstetrics and Gynaecology, Cork University Maternity Hospital, Ireland 2 11. Assessment of interhemispheric synchrony in preterm EEG by means of the Activation Synchrony Index (ASI) Anneleen Dereymaeker1, Ninah Koolen2, Gunnar Naulaers1, Katrien Jansen1, Jan Vervisch1, Sabine Van Huffel2, Maarten Devos3, Sampsa Vanhatalo4, 1 University Hospitals Leuven, Belgium Department of Electrical Engineering, (ESAT) KU Leuven, Belgium 3 Department of Engineering Science, Institute of Biomedical Engineering, University of Oxford, UK 4 Department of Children’s Clinical Neurophysiology, HUS Medical Imaging Center and Children’s Hospital, Helsinki University Central Hospital, Finland 2 Theme 2 - Neuroprotection strategies in the neonate 12. Using cerebrovascular reactivity to determine optimal blood pressure and the risk for IVH in a cohort of preterm infants Zachary Vesoulis , Steve Liao, Nathalie El Ters, Shamik Trivedi, Amit Mathur, Washington University School of Medicine, United States 13. Establishing Neonatal Neuro-Critical Care program using multidisciplinary team approach to Hypoxic Ischemic Encephalopathy to build the model (a 2 year experience) Khorshid Mohammad, University of Calgary, Canada 14. Redefining normative blood pressure in very preterm infants using a massive data approach Zachary Vesoulis , Steve Liao , Nathalie El Ters , Shamik Trivedi , Amit Mathur , Washington University, United States 21: 15. Differences in hospital care and brain injury in newborns receiving therapeutic hypothermia. MJ Harbert 1,2, Mridu Sinha 2, Sheila Rosenberg 2, Rachelle Sey 1, Kathy Arnell 1, Linda Salinda 1, Todd Coleman 2, Maynard Rasmussen 1, 1 Sharp Mary Birch Hospital for Women and Newborns, United States of California San Diego, United States 2 University 16. Feasibility study on the potential of giving neuroprotective treatment to neonates with hypoxic ischemic encephalopathy in low resource settings Thérèse Biselele 1, Gunnar Naulaers 2, Huibert Tjabbes 3, Jephté Bambi1, Gabriel Tabu4, Josy Kapinga 4, Valérie Bola 5, Bruno Tady 1, Cacha Peeters-Scholte 3, 1 Neonatal Unit, Department of Pediatrics, University Hospital of Kinshasa, DR Congo Pregnancy, Fetus and Newborn, Department of Growth and Regeneration, KU Leuven, Belgium 3 Neurophyxia BV, The Netherlands 4 Neonatal Unit, Department of Pediatrics, Clinique Ngaliema, DR Congo 5 Neonatal Unit, Department of Pediatrics, Hopital Saint Joseph, DR Congo 2 17. Body Hypothermia Neuroprotective in Neonates with Hypoxic-ischemic Encephalopathy: Five Years of the Beginning of the Protocol in a Private Hospital in São Paulo, Brazil. Mauricio Magalhaes, Renata Yoshida, Frederico Pires, Arno Warth, Maria Fernanda Dornaus, Alice Deutsch, Hospital Israelita Albert Einstein, Brazil 18. A resuscitation scale for predicting the need for therapeutic hypothermia. MJ Harbert 1,2, Melissa Brown 1, Nicole George 1, Danielle Lazarus 1, Sarah Jane Steen1, Madeline Wozniak 1, Deborah Poeltler 1, D Maynard Rasmussen 1, 1 2 Sharp Mary Birch Hospital for Women and Newborns, United States University of California, San Diego, United States 19. Therapeutic Hypothermia: Six years' experience in a Single Tertiary Center in Brazil Gabriel Fernando Todeschi Variane , Francisco Paulo Martins Rodrigues, Erica Vince Marrara, Maria Renata Tollio Chopard, Clery Bernardi Gallacci, Paulo Roberto Pachi, Victoria Catarina de Albuquerque Melo, Amanda Melhado, Tabajara Barbosa Lima Neto, Inês Oliveira, Maurício Magalhães, Santa Casa De Sao Paulo, Brazil 22: 20. Brain MRI Outcomes Following Darbepoetin Administration in Newborns Undergoing Hypothermia for Hypoxic-ischemic Encephalopathy Mariana Baserga 1, Betsy Ostrander 1, Joanna Beachy 1, Bradley Yoder 1, Robert McKinstry 2, Robin Ohls 3, William Walsh 4, Dennis Mayock 5, Sandra Juul 5, Robert Christensen 1, 1 University of Utah, USA Washington University, USA 3 University of New Mexico, USA 4 Vanderbilt University, USA 5 University of Washington, USA 2 21. Therapeutic Hypothermia: Is it safe and feasible to cool neonates in a low resource setting? Gabriel Fernando Todeschi Variane, Erica Vince Marrara, Maria Renata Tollio Choppard, Victoria Catarina de Albuquerque Melo, Beatriz Helena de Moraes Milioni, Amanda Melhado, Maruício Magalhães, Irmandade da Santa Casa de Misericordia de Sao Paulo, Brazil 22. Feasibility and safety of combining therapeutic hypothermia with magnesium sulfate administration, in the management of neonates with hypoxic ischemic encephalopathy- randomized control trial. Ewa Gulczynska1, Janusz Gadzinowski2, Marek Nowiczewski1, Barbara Sobolewska1, Joanna Caputa2, Anna Maczko3, Wojciech Walas3, Tomasz Talar1, 1 Polish Mother's Memorial Hospital-Research Institute, Poland University of Medical Sciences, Department of Neonatology; Poland 3 District Medical Center Opole; Poland 2 Theme 3 - Continuous EEG monitoring – theory and applications 23. Video EEG (vEEG) Characteristics In Newborns After Selective Head Cooling (SHC) And Correlation With Abnormal Brain Imaging Elena Wachtel, Hannaise Cruz, Pradeep Mally, New York University Medical Center, United States 24. The First Year of a Dedicated Neuro-NICU: Outcomes Elisabeth Yan, Krisa Van Meurs, Courtney Wusthoff, Patients, Treatments, and Stanford University, United States 23: 25. Rewarming Induces EEG Background Deterioration in Term Newborns with Hypoxic-Ischemic Encephalopathy Undergoing Therapeutic Hypothermia Ala Birca, Anne Lortie, Gregory Anton Lodygensky, Jean-Claude Decarie, Veronica Birca, Anne Gallagher, Mathieu Dehaes , Lionel Carmant, CHU Sainte-Justine, Canada 26. The role of early amplitude integrated EEG in monitoring neonates at high risk for brain injury Gabriel Fernando Todeschi Variane, Renato Gasperini, Heitor Castelo Branco Rodrigues Alves, Thiago Luiz Pereira Donoso Scoppetta, Rodrigo Jesus Gonçalves Figueredo, Francisco Paulo Martins Rodrigues, Mauricio Magalhães, Irmandade da Santa Casa de Misericórdia de São Paulo, Brazil 27. EEG background activity and seizure burden are associated with brain injury on MRI and neurodevelopmental outcome in full-term infants with hypoxicischaemic encephalopathy. Lauren Weeke1 , Geraldine B. Boylan2, Ronit Pressler3, Boubou Hallberg4, Floris Groenendaal1, Linda de Vries1, 1 Department of Neonatology, Wilhelmina Children's Hospital, University Medical Centre Utrecht, The Netherlands 2 Irish Centre for Fetal and Neonatal Translational Research, University College Cork, Ireland 3 Section of Clinical Neurosciences and Neonatal Unit, University College London, London, UK, 4 Department of Neonatology, Karolinska University Hospital, Stockholm, Sweden 28. Electrophysiological Diagnostic Methods of Newborn’s Paroxysmal Disorders Dariia Kostiukova 1, Elizabeth Schunko 2, Tetyana Orlova 1, Tetyana Konchakovska 2, , 1 2 National Children’s Specialized Hospital “OHMATDYT”, Ukraine P.L. Shupyk National Medical Academy of Postgraduate Education, Ukraine 29. Early stability of brain activity cycling (BAC) predicts outcome in extremely preterm babies Susanna Stjerna1, Nathan J Stevenson2, Sverre Wikström2, Ingrid Hansen-Pupp 4, David Ley 4, Lena Hellström-Westas 3,Sampsa Vanhatalo 1, 1 University of Helsinki, Finland University College Cork, Ireland 3 University of Uppsala, Sweden 4 University of Lund, Sweden 2 24: 30. P.A.N.D.A.S (Providing Amplitude Integrated Electroencephalography in Neonates with Drug Abstinence Syndrome) Jamie Limjoco 1, Meghan Brodhead 2, Lucyna Zawadzki 1, Jens Eickhoff 1, Chrysanthy Ikonomidou 1, 1 2 University of Wisconsin School of Medicine and Public Health, United States Pharmacy, Meriter-Unity Point Health, United States 31. aEEG Abnormalities in Neonates with Complex Congenital Heart Disease Donna Goff, Andrea Pardo, Priscilla Pegis, Douglas Deming, Andrew Hopper, Loma Linda University Children's Hospital, United States 32. Remote Real Time Decision Support with the Babylink Platform Cillian O'Driscoll, Geraldine B Boylan, Gordon Lightbody, Liam Marnane, Irish Centre for Fetal and Neonatal Translational Research , University College Cork, Ireland 33. Amplitude-duration duality of EEG interbursts in term asphyxiated infants and correlation with outcome Anneleen Dereymaeker1, Vladimir Matic2, Sabine Van Huffel2, Katrien Jansen 1, Jan Vervisch 1, Paul Govaert 3, Gunnar Naulaers 1, 1 Neonatology and Child Neurology, University Hospitals Leuven,, Belgium Department of Electrical Engineering (ESAT) KU LEUVEN, Belgium 3 ZNA Middelheim, Belgium 2 34. Term Equivalent Amplitude Integrated EEG (aEEG) Measures Predict Brain Injury in Preterm Infants Nathalie El Ters 1, Christopher Smyser 2, Zachary Vesoulis 1, Steve Liao 1, Rakesh Rao1, Shamik Trivedi 1, Amit Mathur 1, 1 Department of Pediatrics, Division of Newborn Medicine, Washington University School of Medicine, United States 2 Department of Neurology, Division of Child Neurology, Washington University School of Medicine, United States 35. Detecting inter-burst intervals in the EEG of preterm infants John O' Toole 1, Rhodri O. Lloyd 1, Robert M. Goulding 1, Sampsa Vanhatalo 2, Geraldine B. Boylan 1, Nathan J Stevenson 1, 1 Neonatal Brain Research Group, Irish Centre for Fetal and Neonatal Translational Research (INFANT), University College Cork, Ireland 2 Department of Children’s Clinical Neurophysiology and HUS Medical Imaging Centre, Helsinki University Central Hospital and University of Helsinki, Finland 25: 36. Education of NICU Providers in Amplitude Integrated EEG Interpretation Krisa Van Meurs 1, Kathi Randall 1, Catherine Clark 2, Christina Williams 3, Christine Little 1, Courtney Wusthoff 2, 1 Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine, United States 2 Division of Child Neurology,Department of Neurology and Neurologic Sciences, Stanford University School of Medicine, USA 3 Stanford University School of Medicine, USA 37. Early Continuous Multichannel EEG in a Case of Molybdenum Cofactor Deficiency Claire Power 1, Caroline Ahearne 2, Niamh McSweeney 1, Brendan Murphy 3, Geraldine B Boylan 2, 1Department of Paediatrics, Cork University Hospital, Cork, Ireland Centre for Fetal and Neonatal Translational Research, University College Cork, Ireland 3Department of Neonatology, Cork University Maternity Hospital, Cork, Ireland 2Irish Theme 4 - Other forms of brain monitoring, such as NIRS, fMRI, biochemical, etc. 38. Cerebral Hemodynamics in Newborns Undergoing Hypothermia Therapy: A Multiple-Time-Scale Approach Lina Chalak, Tian Fenghua, Rong Zhang, UT Southwestern Medical Center Dallas, United States 39. Quantitative analysis of cranial ultrasonographic periventricular echogenicity in preterm infants Tammy Beller1, Tali Peylan1, Liat Ben Sira2, Loren Levi1, Shelly Irene Shiran2, Haim Bassan1, 1 2 Child Neurology and Development, Tel Aviv Medical Center, Tel Aviv University, Israel Department of Radiology, Tel Aviv Medical Center, Tel Aviv University, Israel 40. Developmental Outcomes Following White Matter Injury To Optic Radiations in Neonates Exposed to Chorioamnionitis Lakshmi Katikaneni, Lee Hewett, Denise Mulvihill, Katherine Hope, Andrew Barbour, Truman Brown, Dorothea Jenkins, MUSC, United States 26: 41. Serum Biomarkers Of Neuronal Injury In Newborns Who Were Evaluated For Hypoxic Ischemic Encephalopathy But Did Not Qualify For Head Cooling, Compared To Normal Newborns: A Pilot Study Elena Wachtel, Uday Patil, Pradeep Mally, New York University Medical Center, United States 42. Near-infrared Spectroscopy and Detection of a Significant Patent Ductus Arteriosus Valerie Chock, Laura Rose, Jet Mante, Rajesh Punn, Stanford University, United States 43. EEG Maturation and Stability of Cerebral Oxygen Extraction in Very Low Birth Weight Infants Mohamed El-Dib1,2, Rathinaswamy Govindan2, Safwat Aly1,2, Khalid Alyami1, Saleh Alqahtani1, Ahmad Ibrahim1, Mohamed Mohamed1,2, Adre du Plessis1,2, Hany Aly1,2, 1 2 The George Washington University, United States Children's National Health System, United States 44. Effects of Anesthesia on Amplitude-integrated EEG (aEEG) in Neonates Nidhi Shah 1, Alexis Davis 2, Krisa Van Meurs 1, 1 2 Stanford University/Lucile Packard Children's Hospital, United States Good Samaritan Hospital, Pediatrix Medical Group, United States 45. Outcome Prediction in Neonates with Intraventricular Hemorrhage using a functional MRI Score Katharina Goeral 1, Gregor Kasprian 2, Christiane Leeb 1, Renata Fuiko 1, Angelika Berger 1, Monika Olischar 1, Katrin Klebermass-Schrehof 1, 1 Department of Pediatrics and Adolescent Medicine - Division of Neonatology, Intensive Care and Pediatric Neurology, Medical University of Vienna, Austria 2 Department of Radiology - Division of Neuroradiology and Musculoskeletal Radiology, Medical University of Vienna, Austria 27: 46. Amplitude integrated EEG and near-infrared spectroscopy in neonates with hypoxic-ischemic encephalopathy Katharina Goeral 1, Vito Giordano 1, Gregor Kasprian 2, Lisa Schmidt 1, Berndt Urlesberger 3, Katrin Klebermass-Schrehof 1, Monika Olischar 1, 1 Department of Pediatrics and Adolescent Medicine - Division of Neonatology, Intensive Care and Neuropediatrics, Medical University of Vienna, Austria 2 Department of Radiology - Division of Neuroradiology and Musculoskeletal Radiology Medical University of Vienna, Austria 3 Department of Pediatrics and Adolescent Medicine - Division of Neonatology, Medical University of Graz, Austria 47. Cerebral oxygenation in preterm infants less than 32 weeks during the first 48 hours of life William Hutch 1, Eugene Dempsey 1,2, Rhodri Lloyd 1, John O' Toole 1, Margret Wall , Mmoloki Kenosi 2, Vicky Livingstone 1, Geraldine B Boylan 1,2, 1 2 Irish Centre for Fetal and Neonatal Translational Research, University College Cork, Ireland Department of Paediatrics, University College Cork, Ireland 48. Monitoring Seizures in Neonates using simultaneous Near Infrared Spectroscopy (NIRS) and Electroencephalogram (EEG). A Systematic Review William Hutch 1, Eugene Dempsey 1,2, Geraldine B Boylan 1,2, 1 2 Irish Centre for Featal and Neonatal Translational Research, University College Cork, Ireland Department of Paediatrics, University College Cork, Ireland 49. Impact of extrauterine life on normal maturation of visual evoked potentials in preterm infants Eva Schwindt , Vito Giordano , Zsofia Rona , Christine Czaba-Hnizdo , Monika Resch , Thomas Waldhoer , Renate Fuiko , Katrin Klebermass-Schrehof Medical University Vienna, Austria 50. Prospective Study Of The Cortical Haemodynamic Response Of Burst Suppressed Or Discontinuous Electroencephalographic Activity In Infants With Hypoxic Ischaemic Encephalopathy. Maria Chalia 1,2, Robert Cooper 1,3, Laura Dempsey 1,3, Andrea Edwards 1,2, Chuen Wai Lee 1,2, Andrew Michell 2, Sabrina Brigadoi 1,3, Nick Everdell 1,3, Jeremy Hebden 1,3, Topun Austin 1,2, 1 neoLAB, The Evelyn Perinatal Imaging Centre, Cambridge University Hospital, NHS Foundation Trust, United Kingdom 2 Department of Neonatology, Cambridge University Hospital, NHS Foundation Trust, United Kingdom 3 Department of Medical Physics and Biomedical Engineering, University College London, United Kingdom 28: 51. Association between placental pathology and NIRS in the first 7 2 hours of life in preterm babies. Silvia Cecilia Pisoni 1,2, Petra M.A. Lemmers 1, Thomas Alderliesten 1, Manon J.N. Benders 1, Peter G.J. Nikkels 3, Frank van Bel 1, Wim Baerts 1, 1 Wilhelmina Childrens Hospital, University Medical Center Utrecht, The Netherlands Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, University of Milan, Department of Clinical Sciences and Community Health, Italy 3 University Medical Center Utrecht/Department of Pathology, The Netherlands 2 52. Sleep- wake- cycling in amplitude- integrated EEG – what do we see in polysomnography? Lisa Schmidt 1, Alexandra Hausmann , Vito Giordano , Zsofia Rona , Tobias Werther, Sampsa Vanhatalo , Angelika Berger , Katrin Klebermass-Schrehof 1 Medical University Vienna, Austria 53. Evaluation of early MRI and interrater agreement in cooled neonates in a single tertiary center in Latin America Gabriel Fernando Todeschi Variane, Erica Vince Marrara, Heitor Castelo Branco Rodrigues Alves, Thiago Luiz Pereira Donoso Scoppetta, Renato Gasperini, Maurício Magalhães, Santa Casa De São Paulo - SP Brazil, Brazil 54. Determining the relationship between thresholds of cerebral hypoxia and adverse outcome in preterm infants Cristine Sortica Da Costa1, Gordon Stevenson1, Marek Czosnyka2, Peter Smielewski2, Topun Austin1, 1 2 Neonatal Unit, Rosie Hospital, Cambridge University Hospitals, NHS Foundation Trust, United Kingdom Brain Physics Lab, Academic Neurosurgical Unit, University of Cambridge, United Kingdom 55. Detecting brain injury in the preterm infant with cerebral oxygenation monitoring John O' Toole, Mmoloki Kenosi, Geraldine B. Boylan , Eugene Dempsey Neonatal Brain Research Group, Irish Centre for Fetal and Neonatal Translational Research (INFANT), University College Cork, Ireland 29: 56. Quantitating poly-unsaturated fatty acids in neonates with hypoxic-ischemic brain injury Jessica Wisnowski 1,2,3,4, Aaron Reitman 1,2, Tai-Wei Wu 5, Eugenia Ho 1,2, Douglas Vanderbilt 1,2, Claire McLean 1,2,Philippe Friedlich 1,2, Marvin Nelson 1,2, Ashok Panigrahy 1,2,3, Stefan Bluml 1,2,4, 1 Children's Hospital Los Angeles, United States University of Southern California, United States 3 Children's Hospital of Pittsburgh of UPMC, United States 4 Rudi Schulte Research Institute, United States 5 Chang Gung Memorial Hospital, Taiwan 2 Theme 5 - Long‐term outcome studies 57. A New Validated Clinical MRI Injury Scoring System in Neonatal HypoxicIschemic Encephalopathy Shamik Trivedi 1,. Rakesh Rao 1, Zachary Vesoulis 1, Preethi Srinivasakumar 2, Steve Liao 1, Amit Mathur 1, 1 Edward Mallinckrodt Department of Pediatrics, Washington University School of Medicine, United States Department of Pediatrics-Neonatal Perinatal Medicine, University of Texas Southwestern Medical Center, United States 2 58. Examining the Validity of a Digitalised Assessment of Executive Functioning for Toddlers: The BabyScreen App Conal Wrigley 1,3, Caroline Ahearne 2,3, Raegan Murphy 1, Deirdre Murray 2,3, 1 School of Applied Psychology, University College Cork, Ireland Department of Paediatrics and Child Health, , University College Cork, Ireland 3 Irish Centre for Fetal and Neonatal Translational Research, University College Cork, Ireland 2 59. Heart rate variability in infants with hypoxic ischaemic encephalopathy: correlation with 2-year neurodevelopmental outcome Robert Goulding 1,2, Nathan J Stevenson 1, Caroline Ahearne 1,2, Peter Filan 1,2, Geraldine B Boylan 1,2, 1 2 INFANT Centre, Neonatal Brain Research Group, University College Cork, Ireland Department of Neonatology, Cork University Maternity Hospital, Cork, Ireland 60. Bayley Scales Of Infant And Toddler Development (Edition 3): How Does The 2 Year-Old Irish Population Compare? Caroline Ahearne 1,2, Geraldine Hannon 1, Mairead Kiely 1, Louise Kenny 1, Jonathan Hourihane 2, Deirdre Murray 1,2, 1 2 Irish Centre for Fetal and Neonatal Translational Research, University College Cork, Ireland Department of Paediatrics and Child Health, University College Cork, Ireland 30: 61. High electrographic seizure burden in neonatal hypoxic ischemic encephalopathy is associated with abnormal outcome at 24 - 48 months. Liudmila Kharoshankaya 1,2, Nathan J Stevenson 1, Vicki Livingstone 1, Deirdre Murray 1,2, Caroline Ahearne 1,2, Brendan Murphy 3, Geraldine B Boylan 1,2, 1 Neonatal Brain Research Group, Irish Centre for Fetal and Neonatal Translational Research (INFANT), University College Cork, Ireland 2 Department of Paediatrics and Child Health, University College Cork, Ireland 3 Department of Neonatology, Cork University Maternity Hospital, Ireland 62. Predictive value of early cEEG for developmental outcome at 24-48 months in cooled neonates with hypoxic ischemic encephalopathy. Liudmila Kharoshankaya1,2, Vicki Livingstone1, Brendan Murphy3, Geraldine B Boylan1,2, 1 Neonatal Brain Research Group, Irish Centre for Fetal and Neonatal Translational Research (INFANT), University College Cork, Ireland 2 Department of Paediatrics and Child Health, University College Cork, Ireland 3 Department of Neonatology, Cork University Maternity Hospital, Ireland 63. Predictors of short and long-term outcome in cooling era: five years experience Silvia Malguzzi, Gaia Kullmann, Giuseppe Paterlini, Davide Bernasconi, Paolo Tagliabue, MBBM Foundation - San Gerardo Hospital Monza, Italy Theme 6 – Seizures 64. Performance measurement of an automated neonatal seizure detector in EEG seizure data showing inter-rater disagreement Amir Hossein Ansari 1,2, Perumpillichira Joseph Cherian 3, Vladimir Matic 1,2, Anneleen Dereymaeker 4, Leen De Wispelaere 5, Charlotte Dielman 6, Jan Vervisch 4, Paul Govaert 5, Gunnar Naulaers 4, Maarten De Vos 7, Sabine Van Huffel 1,2, 1 Department of Electrical Engineering (ESAT-STADIUS), KU Leuven, Leuven, Belgium, Belgium iMinds-KU Leuven Medical IT Department, Leuven, Belgium, Belgium 3 Section of Clinical Neurophysiology, Department of Neurology, Erasmus MC, Rotterdam,The Netherlands 4 Department of Development and Regeneration, Neonatology, University of Leuven, Leuven, Belgium, Belgium 5 Section of Neonatology, Department of Pediatrics, Sophia Children’s Hospital, Erasmus MC, Rotterdam, The Netherlands 6 Paola ziekenhuis/hospital-ZNA, Antwerp, Belgium 7 Institute of Biomedical Engineering, Department of Engineering, University of Oxford, UK 2 31: 65. Treatment variability for seizures in newborns: results from the multicenter Neonatal Seizure Registry Renee Shellhaas 1, Courtney Wusthoff 2, Taeun Chang 3, Nicholas Abend 4, Catherine Chu 5, M. Roberta Cilio 6, Sonia Bonifacio 6, Shavonne Massey 4, Tammy Tsuchida 3, Faye Silverstein 1, Janet Soul 7, Hannah Glass 6, 1 University of Michigan C.S. Mott Children's Hospital, United States Lucille Packard Children's Hospital, Stanford University, United States 3 Children's National Medical Center, United States 4 Children's Hospital of Philadelphia, United States 5 Massachusetts General Hospital, United States 6 University of California, San Fransisco, Benioff Children's Hospitall, United States 7 Children's Hospital Boston, United States 2 66. Early Seizure Detection in At Risk Neonates using Amplitude Integrated EEG (aEEG) Cecelia Glennon, Rachel Small, Lucile Packard Children's Hospital at Stanford University, United States 67. Seizures in premature infants less than 28 weeks gestation Eilon Shany 1, Hila Zur-Sebton 2, Irina Meledin 1, Michael Friger 2, 1 2 Ben Gurion University of the Negev and Soroka Medical Center, Israel Ben Gurion university of the Negev, Israel 68. Reliability and usefulness of the Recognize seizure detection software in management of neonatal seizures on the NICU: An observational study. Mamata Jalisatgi 1, Archana Mishra, 1 Royal Bolton Hospital, United Kingdom 69. Changes in cerebral oxidative metabolism during recurrent neonatal seizures Subhabrata Mitra 1, Gemma Bale 2, Sean Mathieson 1, Cristina Uria-Avellanal 1, Judith Meek 1,Ilias Tachtsidis 2, Nicola Robertson 1, 1 2 Institute for Women's Health, University College London, United Kingdom Department of Medical Physics and Bioengineering, University College London, United Kingdom 70. Optimising Treatment of Neonatal Seizures with Bumetanide Maria Donovan 1,2, Geraldine B Boylan 3,4, John Cryan 2,5, Brendan Griffin 1, 1 School of Pharmacy, University College Cork, Ireland Department of Anatomy and Neuroscience, University College Cork, Ireland 3 Irish Centre for Fetal and Neonatal Translational Research, University College Cork and Cork University Maternity Hospital, Ireland 4 Department of Paediatrics and Child Health, University College Cork, Ireland 5 Alimentary Pharmabiotic Centre, Ireland 2 32: Theme 7 - Withdrawal of care and other challenging decisions 71. Factors associated with mortality in the era of therapeutic hypothermia for neonatal encephalopathy. Maynard Rasmussen 1, MJ Harbert 1,2, Melissa Brown 1, Danielle Lazarus 1, Deborah Poeltler 1, 1 2 Sharp Mary Birch Hospital for Women and Newborns, United States University of California, San Diego, United States 72. Walker-Warburg syndrome: a case series. Ana Luiza Teixeira Balloti, Rafaela Fabri Rodrigues, Gabriel Variane, Maurício Magalhães, Irmandade Da Santa Casa De MisericóRdia De SãO Paulo, Brazil 33: Social Calendar Welcome Reception and Buffet – Thursday 1st Oct 19.30 Join us at the Fota Island Golf Club, just a few minutes’ walk from Fota Island Resort for an informal Welcome Reception and Buffet from 19:30pm on Thursday the 1st of October. Relax and unwind with Traditional Irish music and food in the wonderful ambience of The Spike Bar. Nestled in the grounds of Fota Island Resort, Fota Clubhouse is an extremely creative conversion of old stone farm buildings with views across the Fota golf courses and water features. 4km Charity Fun Run – Friday 2nd Oct 07.00am Please join us for a charity 4km Fun Run, through the grounds of Fota Island Resort, in aid of the Jack & Jill Foundation. The Jack & Jill Foundation provides nursing care and support for children with severe neurological development issues, as well as offering some respite to the parents and families Jack & Jill provides direct funding to families, enabling them to buy home respite care to give them a break, providing support through home visits from nurses and bereavement support. The Foundation cannot cure the children but it can help to alleviate some of the difficulties that exist. We will meet in the Hotel Lobby and request a small donation of All Donations would be appreciated and all monies raised from the FUN RUN will go towards providing home respite care for families. 34: www.natus.com Olympic Brainz Monitor CFM The Olympic Brainz Monitor is the latest technology in cerebral function monitoring (CFM), including Seizure Detection software and an optional software for automatically mark the trace to suggest background patterns, allowing you to begin monitoring in 3 easy steps: Plug in unit, apply electrodes and start recording. BEST IN CLASS NEWBORN DEDICATED aEEG MONITOR UNIQUE SOFTWARE PACKAGES: BACKGROUND PATTERN CLASSIFICATION Automated Background Pattern Classification Software for the Olympic Brainz Monitor that automatically applies clinical criteria to the aEEG trace to assist in identifying the baseline pattern classification. RECOGNIZE SEIZURE DETECTION Automated Seizure Detection Software for the Olympic Brainz Monitor that conveniently marks the aEEG and EEG traces to indicate areas of suspected seizure activity during an aEEG study. CONTINUOUS BEDSIDE CEREBRAL FUNCTION MONITORING – PROVIDING ACTIONABLE INFORMATION WHEN YOU NEED IT MOST… Natus Medical Incorporated 1501 Industrial Road San Carlos, CA 94070 USA 1-800-303-0306 +1-650-802-0400 For any information please contact: pierre.radzikowski@natus.com Thank you to our Sponsors Sponsors and Exhibitors Workshop Sponsors Workshop A:Interpreting the Neonatal EEG, Workshop E:aEEG for the Experienced User, Workshop F:NIRS-monitored brain oxygenation, Thank you to our Sponsors Gold Sponsors Silver Sponsors