- isott 2016

Transcription

- isott 2016

The 44th Annual Meeting
International Society on Oxygen Transport to Tissue
Organizing Committee
ISOTT President
Howard J. Halpern, University of Chicago
Local Committee
Hao F Zhang, Northwestern University
Joseph Culver, Washington University in St. Louis
Boris Epel, University of Chicago
ISOTT 2016. Chicago. July 10 t h – 14 t h
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Oral presentations
Sunday, 10th
16:00
19:00
Reception
Session 1: Chair Howard J. Halpern
19:00
20:00
Gregg L. Semenza
Oxygen, glucose metabolism, and breast cancer stem cells
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Monday, 11th
8:30
8:45
8:45
9:25
9:25
9:55
9:55
10:10
10:10
10:25
10:25
10:55
10:55
11:25
11:25
11:40
11:40
12:10
12:10
13:40
13:40
14:20
14:20
14:40
14:40
14:55
14:55
15:10
15:10
15:50
15:50
16:05
16:05
16:20
16:20
16:35
16:35
16:50
16:50
17:50
19:00
21:00
Conference foreword
Session 2. Chairs: Boris Epel and Manjari Rain
Samuel Achilefu
Breaking the oxygen and tissue depth dependency of
photodynamic therapy with nanophotosensitizers
Murali C. Krishna
MRI and EPR based Imaging Biomarkers to Guide
Treatment in Tumor Bearing Mice
Paul Okunieff
Enterade decreases radiation-induced nausea in mice using
a pica model
Coffee break
Session 3. Chairs: Peter Vaupel and Rong-Wen Tain
John W.
Eight sages over five centuries share oxygen’s discovery
Severinghaus
Lin Z Li
Optical imaging of mitochondrial redox state in cancer
transformation and progression
Yuya Enokida
Directional migration of MDA-MB-231 cells under O2/pH
gradients
Rapid Fire presentations P1-P14
Lunch
Session 4. Chairs: Harold M. Swartz and Leonard Che Fru
Peter Vaupel
Tumor Oxygenation Status: Facts and Fallacies
Arnulf Mayer
Multiparametric analysis of the tumor microenvironment:
Hypoxia markers and beyond
Anne Riemann
Hypoxia-related tumor acidosis affects the miRNA
expression pattern in prostate and breast tumor cells
Coffee break
Session 5. Chairs: Sabine van Huffel and Anne Riemann
Paul T Schumacker
Mitochondrial ROS regulate cell stress response
Rong-Wen Tain
Characterization of the Intrinsic MRI Relaxation Properties of
Hydroxyl ROS
Ju Jin
Evaluation of free radical scavenging capacity and antioxidative damage effect of resveratrol-nanostructured lipid
carrier
Adrien Lücker
The relative influence of hematocrit and red blood cell
velocity on oxygen transport from capillaries to tissue
David Highton
Slow oscillations in electroencephalography and cerebral
oxygenation following acute brain injury.
Poster session
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Boat trip
Tuesday, 12th
8:30
9:10
9:10
9:50
9:50
10:05
Session 6. Chairs: Joseph C. Lamanna and Alexander Caicedo Dorado
Nanduri R
Oxygen sensing by the carotid body
Prabhakar
Robert A.
Unique features of oxygen delivery to the mammalian retina
Linsenmeier
Michelle Puchowicz
Diet-induced ketosis protects against focal cerebral ischemia
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10:05
10:45
10:45
11:00
11:00
11:20
11:20
11:35
11:35
11:50
11:50
12:05
12:05
12:20
12:20
12:50
14:20
12:50
14:20
15:00
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15:45
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16:15
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in mouse
Conference photograph / Coffee break
Session 7. Chairs: Oliver Thews and Michal G Gonet
Lin Z Li
Imaging redox state of mouse muscles of different ages
Claudine Kieda
Imaging Cancer hypoxia alleviation for monitoring adjuvant
tumor therapies
Leonard Che Fru
Potential role of the glycolytic oscillator in acute hypoxia in
tumors
(Lina Xu)
Computational Simulation of Tumor Hypoxia Using
Peter Vaupel
Experimental Data from a Dorsal Skin Window Chamber
Kyung A. Kang
Gold Nanoparticle based, Fluorescent Contrast agent with
Enhanced sensitivity/selectivity for MDA-MB 231
Lin Z Li
Identification of redox-associated gene expressions in
dissected tissues from mouse xenografts of human breast
cancer
Session 8. Chairs: Gareth R. Eaton and Frederic Lange
Executive board meeting / Lunch
Harold M. Swartz
Clinical trials with EPR oximetry update: progress,
challenges, and some lessons learned
Periannan
Initial Results of Phase 1 clinical trial of OxyChip, an
Kuppusamy
implantable pO2 sensor for tumor oximetry
Ann B. Flood
Reviewing the longterm risks of injections of India ink used
as an EPR oximetry sensor
Coffee break
Session 9. Chair: Ann B. Flood and Guennadi Saiko
Gareth R. Eaton
RF frequency dependence of trityl electron spin relaxation
and signal-to-noise
Boris Epel
Tumor oxygen-guided radiation therapy optimization
Martyna Elas
Oxygen and redox mapping in animals in vivo using CW Lband EPR
Poster session
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Wednesday, 13th
8:30
9:00
9:00
9:15
9:15
9:45
9:45
10:00
10:00
10:15
10:15
10:30
10:30
10:45
10:45
11:15
11:15
11:30
11:30
11:45
Session 10. Chairs: Clare E. Elwell and Andreas J. Metz
James S. Hyde
Neuro-vascular coupling in brain mediates oxygen transport
D. S. Fahmeed
Imaging metabolic heterogeneity of the tumor
Hyder
microenvironment
Song Hu
Photoacoustic Microscopy of the Cerebral Metabolic Rate of
Oxygen in Mice
(Pardis Kaynezhad)
A new miniature broadband near-infrared spectroscopy
Ilias Tachtsidis
system for real-time measurement of brain tissue
oxygenation and metabolism
Isabel de Roever
Functional NIRS measurements of cytochrome-c-oxidase
demonstrate a more depth-resolved marker of frontal lobe
activation compared to the haemoglobins
Gemma M. Bale
Using near-infrared spectroscopy to measure cerebral blood
flow during spontaneous oxygenation changes in neonatal
brain injury
Coffee break
Session 11. Chairs: Gemma Bale and Wilson A. Schreiber
Chien Ho
NMR Spectroscopy and X-ray Crystallography Are Providing
An Evolving Picture of Hemoglobin as the Oxygen Carrier of
Vertebrates
Franca Schmid
Depths dependent flow and pressure characteristics in
cortical microvascular networks
Chuan He
Environmental enrichment induces increased cerebral
capillary density and improved cognitive function in mice
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11:45
12:00
12:00
12:15
12:15
12:30
12:30
14:00
14:00
14:20
14:20
14:35
14:35
14:50
14:50
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15:05
15:20
15:20
15:35
15:35
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16:20
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16:35
16:35
16:50
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17:20
17:20
18:30
18:30
21:30
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Subhabrata Mitra
Changes in cerebral oxidative metabolism during recurrent
neonatal seizures following perinatal hypoxic ischemic brain
injury
Alexander Caicedo
Relation Between Changes in EEG Activity and Brain
Dorado
Oxygenation in Preterm Infants after Propofol Administration
Andreas J. Metz
Physiological effects of continuous colored light exposure in
humans – A systemic physiology complemented functional
near-infrared spectroscopy (fNIRS) study
Lunch
Session 12. Chairs: Lin Z Li and Molly M Lockart
Ji-Xin Cheng
Imaging and deciphering metabolism at single cell level
Ursula Wolf
Effect of short-term colored light-exposure on cerebral and
systemic physiological activity:
A study applying systemic physiology complemented (SPC)
fNIRS brain imaging
Witold Karol
Factors determining the oxygen permeability of biological
Subczynski
membranes
Sally Pias
Cholesterol-enriched membranes hinder oxygen flow
Phong T Phan
Spatial Distribution of Cellular Oxygen Metabolism in the
Presence of Normal Haemodynamic Responses during
Frontal Lobe Activation using Broadband Near-Infrared
Spectroscopy
Coffee break
Session 13. Chairs: Peter E. Keipert and Qi Liu
Kenneth Schenkman Optical assessment of muscle oxygenation may aid in
optimizing transfusion threshold decisions
Tomiyasu Koyama
Oxygen front in distal vein arterialization in the hind limb in
thick-walled muscle cylinder supported by retrograde
perfusion
George A. Perdrizet
HBOT Suppresses Renal Injury in a Rodent Model of
Diabetes Mellitus
Guennadi Saiko
Methemoglobin: a new way to distinguish burn depth
Joseph C. LaManna
Tissue partial pressure of oxygen measurement during
normoxia and hypoxia using two-photon laser scanning
microscopy
Subhabrata Mitra
Pressure passivity of mitochondrial metabolism is associated
with poor outcome following perinatal hypoxic ischemic brain
injury
Leif Bülow
Recombinant production of blood substitutes in bacteria and
plants – a comparative study
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Conference Banquet
Thursday, 14th
8:30
9:10
9:10
9:25
9:25
9:45
9:45
10:00
10:00
10:25
10:25
10:40
10:40
10:55
Session 14. Chairs: Joseph Culver and Agnieszka E. Drzal
Abdu Alayash
Oxidative pathways and toxicity of extracellular hemoglobin
and blood derived microparticles.
Carleton J.C. Hsia
Nanomedicine using SanFlow - A hemoglobin-based
nanoparticle for critical care and transfusion medicine
Peter E Keipert
Hemoglobin-based oxygen carrier (HBOC) development in
trauma: Past regulatory challenges, lessons learned, and a
path forward
Martin Wolf
Comparison of near infrared spectroscopic tissue oximeters
on a liquid phantom with adjustable oxygenation
Clare E. Elwell
Brain development from birth in Gambian infants
Coffee break
Session 15. Chairs: W. K. Subczynski and Bryan A Clifford
Natalie A
Tissue-integrating oxygen sensors for continuous tracking of
Wisniewski
tissue hypoxia
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10:55
11:10
11:10
11:40
11:40
11:55
11:55
12:10
12:10
13:40
13:40
13:55
13:55
14:10
14:10
14:30
14:50
15:05
14:30
14:50
15:05
17:00
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Frédéric Lange
Evaluation of Hemoglobin and Cytochrome responses
during forearm ischemia using a multiwavelength Time
Domain NIRS system
Valery V. Khramtsov Relationship between tumor hypoxia, redox status and
metabolism in solid tumors: intracellular vs. extracellular
oxidative stress
Mrignayani Kotecha
MRI and Oxygen Imaging in the Assessment of Biomaterials
Yi He
Maximum Likelihood Total Variation Denoising for Photon
Noise
Lunch
Session 16. Chair: Kyung A. Kang and Martyna Elas
(Pardis Kaynezhad)
Optical monitoring of spinal cord tissue oxygenation and
Ilias Tachtsidis
metabolism during hyperoxia in a preclinical model of
Multiple Sclerosis
Zhen Zhang
Evaluation of free radical scavenging capacity with
DPPHABTSOH and the antioxidation of resveratrol
nanoethosomes
Kwang-Sup Soh
Mast cells as the indicator for acupoints and primo nodes
Pan Dong Ryu
The role of the primo-vascular system in hematopoiesis
Coffee break
General meeting
End of conference
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Poster presentations
P1
Atsuhiro Tsubaki
P2
Daisuke Sato
P3
Nana Takehara
P4
P5
Tomotaka Takeda
Yoshiaki Kawakami
P6
Yudai Yamazaki
P7
Yuta Murayama
P8
Alexander Caicedo
Dorado
P9
Agostino Brugnera
P10
Agostino Brugnera
P11
Yutaka Sato
P12
Kaoru Sakatani
P13
Guennadi Saiko
P14
George A. Perdrizet
P15
Gemma M. Bale
P16
Jingjing Jiang
P17
Jinsheng Yang
P18
Linda Ahnen
Cortical oxyhemoglobin elevation persists after moderate-intensity
cycling exercise: A near-infrared spectroscopy study
Site specificity of changes in cortical oxyhemoglobin concentration
induced by water immersion
Changes in cortical oxyhemoglobin during low- and moderate-intensity
cycling exercise: A near-infrared spectroscopy study
PFC blood oxygenation changes through four different cognitive tasks
Relationships between gum chewing and Stroop test
Interindividual differences in exercise-induced spatial working memory
improvement: A near-infrared spectroscopy study
Relation between cognitive function and baseline concentrations of
hemoglobin in prefrontal cortex of elderly people measured by timeresolved near-infrared spectroscopy
CaRMoN: a Matlab Based Toolbox for the Monitoring of Cerebral
Autoregulation Using Near-Infrared Spectroscopy
Cortical and autonomic stress responses in adults with high vs low
levels of anxious symptoms: a pilot study
Age-related changes in physiological reactivity to a stress task: A Near
Infrared Spectroscopy study
Effects of chorus with sign language on anxiety levels and prefrontal
cortex activity at rest measured by near-infrared spectroscopy
Evaluation of pleasure-unpleasure induced by application of lipsticks
using time-resolved near-infrared spectroscopy
NIR spectroscopy of methemoglobin as a predictor of the viability of
burn wounds in humans
Inflammatory Hypoxia: A Common Barrier to Oxygen Delivery to
Tissues
NIRS-Measured Frontal Cortex Asymmetry in Neonatal Brain Injury
A new method based on graphics processing units
for fast near infrared optical tomography
Optical design of adaptive optics confocal scanning laser
ophthalmoscope with two deformable mirror
Near-Infrared Image Reconstruction of Newborns’ Brains: Development
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P19
Adkhamjon Paiziev
P20
Matt Maggio
P21
Richard C. Miller
P22
Howard J. Halpern
P23
Yi He
P24
Sally Pias
P25
Siyu Chen
P26
Bryan A. Clifford
P27
Shun Takagi
P28
Shun Takagi
P29
Takuya Osawa
P30
Takuya Osawa
P31
Ka Zhang
P32
P33
P34
P35
Sandeep S. Chakane
Manjari Rain
Kazuhiro Ichikawa
Michal G Gonet
P36
Michal G Gonet
P37
Agnieszka E. Drzal
P38
Qi Liu
P39
Molly M Lockart
P40
Eiji Takahashi
P41
Robabeh Rahimi
Darabad
P42
Masamichi Moriya
P43
Inema E Orukari
Page |5
and Validation of the Light Sensor
Dorsiflexors muscle oxygenation during low, moderate, and maximal
sustained isometric contractions
Radiation optimization using 3D printed radiation blocks
Correlation between hypoxia proteins and EPR-detected hypoxia in
tumors
Guiding Breast Cancer Prevention with Absolute Oxygen Images
Improving retinal image quality using registration with SIFT algorithm in
qusia-confocal line scanning ophthalmoscope
Lower Than Expected Membrane Permeability to Oxygen, Especially
When Cholesterol Content Is High
Measuring retinal and choroidal circulation oxygen saturation using
visible-light optical coherence tomography (Vis-OCT)
Fast low-rank tensor based dynamic EPR oxygen imaging: improving
subspace estimation with prior information
Effects of 8 weeks training on oxygen dynamics in university rugby
players
Evidence of impaired muscle oxygen utilization during exercise in early
post-myocardial infarction
Delayed onset of reoxygenation in inactive muscles after supra-maximal
cycling exercise
Tissue blood volume parameters measured by continuous-wave and
spatially-resolved NIRS show different changes during prolonged
cycling exercise
Purification of recombinant human hemoglobin from Escherichia coli
crude extracts using molecularly imprinted polymers
XTEN-hemoglobin F: an alternative strategy for PEGylation
Relevance of telomere-telomerase system at high-altitude
Construction of 0.15 Tesla Overhauser enhanced MRI
EPR Image registration with ultrasound advantages and limitations
3D and 4D image reconstruction of data acquired by Bruker EPR E540
L-band imager using EPR-IT software
Effectiveness of oxygen release by ultrasound sensitive O2
microbubbles
Imaging brain hemodynamics after ischemic stroke using visible-light
optical coherence tomography
Binding of inhibitors to cytochrome P450 monooxygenases
Mitochondrial membrane potential in DMOG model of metabolic
reprogramming
In vivo EPR resolution enhancement using techniques known from
quantum computing
Effects of motor imagery on cognitive function and prefrontal cortex
activity in normal adults evaluated by NIRS
The effects of glioma growth on resting state networks in mice
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The Venue
Hilton Chicago / Magnificent Mile Suites
198 E. Delaware Place, Chicago, Illinois 60611-1719, USA
Tel: +1-312-664-1100
Notes on Venue:
• Complimentary breakfast for all ISOTT Participants will
be served at Park Avenue Café on the 2nd floor
•
•
•
Lectures will be held inside the Lakeshore Ballroom on the 3rd floor
GoldCoast Boardroom on the 3rd floor can be used for lecture preparation
Poster session will be held on 3rd floor foyer outside of the lecture room
Coffee breaks will be served in the area outside of the lecture room
Page |8
Sunday July 10th
Social event: Conference Reception
Time: 4 PM- 7 PM
Place: Conference venue, Park Avenue Café, 2nd floor of the Hotel
•
Light meal provided. Beer and Wine provided.
Monday July 11th
Social event: Chicago’s First Lady boat tour.
Time: 7 PM- 9 PM, Boarding will start at 6:45 PM
Place: Chicago River Chicago’s First Lady boat dock, near DuSable Bridge
How to get there:
• The bus will leave Conference Venue at 6:30.
• About 1 mile walk from the Conference Venue
How to get to the boarding location from Hilton Hotel by foot (20 min):
Stroll along Michigan Avenue South from
the Hotel.
After crossing DuSable Bridge across
Chicago River, look for blue awning
marking the kiosk on street level on the
southeast corner of the Michigan Avenue
Bridge at Wacker Drive, then descend the
stairs located there and prepare for
magnificent views of Chicago’s iconic
skyline.
Use 112 E. Wacker Drive for GPS
purposes.
Sandwiches, salad, and assorted
desserts will be catered by Café Ba Ba
Reeba on the cruise. Drinks will be
cash bar.
In case you have time, nearby the
boarding location of “Chicago’s First
Lady”, you can sip coffee at the
Ghirardelli Chocolate Café, or tea at the
Argo Tea Cafe
Page |9
Tuesday July 12th
Social event: Group Photo
Time: 10:05 AM- 10:30 AM
Place: Hancock building, West entrance, on the stairs
•
We will be walking across the street to the Hancock building as a group.
Social event: Poster session/ Reception
Time: 5:30 PM- 7:30 PM
Place: Conference venue, foyer on the 3rd floor of the Hilton Hotel.
•
Light meal provided. Beer and Wine provided.
Wednesday July 13th
Social event: ISOTT 2016 Banquet
Time: 6:30 PM- 9:30 PM
Place: Hancock building, 875 N. Michigan Ave., Chicago, IL 60611. The Signature
Room, 95th floor.
How to get there:
• Come out of the venue main entrance and walk around the right corner of the
Hotel
• Cross E Delaware and walk towards Hancock tower North Entrance.
• There will be signs and staff to assist to get up to the Signature Room.
Announcement:
P a g e | 10
The University of Maryland School of Pharmacy has for sale
a Bruker EleXsys E-540L L-band CW EPR purchased in
2012. The machine has not been used since the 2012
training session.
For more information please contact Pam Crowe
(pcrowe@rx.umaryland.edu).
SPONSOR of ISOTT 2016 Conference
P a g e | 11
SPONSOR of ISOTT 2016 Conference
P a g e | 12
P a g e | 13
SPONSORS of ISOTT 2016 Conference
Department of the Radiation and Cellular Oncology
P a g e | 14
Achilefu, Samuel...... p16
Ahnen, Linda...... p104
Alayash, Abdu...... p71
Angles, Gary...... p62 p110
Bale, Gemma...... p52 p101
Brugnera, Agostino...... p95 p96
Bülow, Leif...... p70 p117 p118
Chakane, Sandeep...... p118
Chen, Siyu...... p111
Cheng, Ji-Xin...... p59
Clifford, Bryan...... p112
Darabad, Robabeh...... p127
Dorado, Alexander...... p57 p94
Drzal, Agnieszka...... p123
Eaton, Gareth...... p43
Elas, Martyna...... p45 p121 p122
Elwell, Clare...... p75
Enokida, Yuya...... p21
Epel, Boris...... p44 p106 p112
Flood, Ann...... p42
Fru, Leonard...... p36
Gonet, Michal...... p121 p122
Halpern, Howard...... p44 p106 p108
Harrison, David......
He, Chuan...... p55
He, Yi...... p81 p109
Heyerick, Arne......
Highton, David...... p30
Ho, Chien...... p53
Hsia, Carleton...... p72
Hu, Song...... p48
Huffel, Sabine...... p57 p94
Hyde, James...... p46
Hyder, D....... p18
Ichikawa, Kazuhiro...... p120
Jiang, Jingjing...... p102
Jin, Ju...... p28
Kang, Kyung...... p38
Kawakami, Yoshiaki...... p91
Kaynezhad, Pardis...... p49 p82
Keipert, Peter...... p73
Khramtsov, Valery...... p79
Kieda, Claudine...... p35
Kotecha, Mrignayani...... p80
Koyama, Tomiyasu...... p65
Krishna, Murali...... p17
Kuppusamy, Periannan...... p41
LaManna, Joseph...... p33 p65 p68
Lange, Frédéric...... p78
Li, Lin Z....... p20 p34 p39
Li, Rupeng...... p47
Linsenmeier, Robert...... p32
Liu, Qi...... p124
Lockart, Molly...... p125
Lücker, Adrien...... p29
Maggio, Matt...... p106
Mayer, Arnulf...... p23
P a g e | 131
Metz, Andreas...... p58
Miller, Richard...... p107
Mitra, Subhabrata...... p56 p69
Moriya, Masamichi...... p128
Murayama, Yuta...... p93
Okunieff, Paul......p130
Orukari, Inema...... p129
Osawa, Takuya...... p115 p116
Padmanabhan, Pradeep......
Paiziev, Adkhamjon...... p105
Perdrizet, George...... p66 p100
Phan, Phong...... p63
Pias, Sally...... p62 p110
Prabhakar, Nanduri...... p31
Puchowicz, Michelle...... p33
Rain, Manjari...... p119
Riemann, Anne...... p24
Roever, Isabel...... p51
Ryu, Pan...... p85
Saiko, Guennadi...... p67 p99
Sakatani, Kaoru...... p93 p95 p96 p97 p98
p128
Sato, Daisuke...... p88
Sato, Yutaka...... p97
Schenkman, Kenneth...... p64
Schmid, Franca...... p54
Schreiber, Wilson......
Schumacker, Paul...... p25
Semenza, Gregg...... p15
Severinghaus, John...... p19
Soh, Kwang-Sup...... p84
Subczynski, Witold...... p61
Swartz, Harold...... p40
Tachtsidis, Ilias......
Tain, Rong-Wen...... p26
Takagi, Shun...... p113 p114
Takahashi, Eiji...... p21 p126
Takeda, Tomotaka...... p90
Takehara, Nana...... p89
Thews, Oliver...... p24
Tsubaki, Atsuhiro...... p87
Vaupel, Peter...... p22 p23
Wisniewski, Natalie...... p76
Wolf, Martin...... p74
Wolf, Ursula...... p60
Xu, Lina...... p37
Yamazaki, Yudai...... p92
Yang, Jinsheng...... p103
Zhang, Ka...... p117
Zhang, Zhen...... p83

- isott 2016

Transcription

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