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Brand Generic Guide
Dr. Reddy’s Laboratories, Inc. BRAND-TO-GENERICTO-BRAND 2016 Edition Conversion Guide Brand-To-Generic-To-Brand Conversion Guide 2016 Dear Healthcare Professional, At Dr. Reddy’s North American Generics, we strive every day to do what matters most to patients –accelerating access to the affordable medicines they need, because Good Health Can't Wait. Each of us is driven by the urgency for good health and committed to providing you with the most affordable products at the best value every day. The medicines we provide to patients and our customers are among the more than 1000 products listed in the Dr. Reddy’s 2016 Brand-to-Generic-to-Brand Conversion Guide. The complimentary pocket guide features an easy-to-use conversion guide and other clinical resources to assist you with conversions, calculations, assessments and more. It includes: • Generic-to-Brand Conversion Guide An alphabetical listing of generic products, cross-referenced to the corresponding brand names 1 • Brand-to-Generic Conversion Guide An alphabetical listing of brand products, cross-referenced to the corresponding generic names • Clinical Resource Section Resources such as charts on liver function assessment, equi-analgesic doses, and high-alert drugs • Product Portfolio The complete Dr. Reddy’s product portfolio is presented in section 2 of the guide. Throughout the guide, Dr. Reddy’s products are printed in color. Introduction SECTION ONE As the 2016 Brand-to-Generic-to-Brand Conversion Guide earns its place as a valuable tool in your clinical setting, know that all of us at Dr. Reddy’s take great pride in, and are committed to, providing you with important resources for the care of your patients. Sincerely, Dr. Reddy’s Laboratories, Inc. 3 SEC 1 Good Health Can't Wait. Access to many of today’s expensive, life-changing medicines remains a hurdle for countless Americans. Helping overcome these barriers to good health and wellness is what drives each and every one of us who work at Dr. Reddy’s North American Generics. Each day, we strive to do what matters most to patients, determined to find the best way to answer their unmet and under-met needs innovatively and with agility. Our 5 promises: •B ringing expensive medicines within their reach by helping reduce the cost of therapy •O ffering products that provide convenience, safety, and efficacy •P roviding education and support to help manage disease better •E nsuring that products are always on the shelf by partnering with our customers •W orking with our partners to help them meet patient needs Uncovering new opportunities for good health has helped us build one of the most expansive offerings in the industry and bring value to the pharmacy and its customers. Dr. Reddy’s products span across major therapeutic categories including gastrointestinal, cardiovascular, pain management, oncology, anti-infectives, pediatrics, and dermatology. More than 60 prescription products are marketed under the Dr. Reddy’s label in over 280 dosing presentations, supported by an aggressive product pipeline with 76 ANDAs pending approval, of which 50 are Para IV certifications and 18 have ‘First To File’ status. Rx-to-OTC switches are supported through our Private Label OTC Group which markets 5 products and more than 150 store-brand packaging presentations. One reason that we’re able to make our medicines affordable is because we manage the entire value chain – from producing the active ingredients to developing formulations to distributing them through our streamlined supply chain. 4 SEC 1 Dr. Reddy’s manufacturing facilities follow cGMP guidelines in the production of API’s and finished dosage forms. Four finished dosage facilities and 9 API facilities currently serve North American Generics. The strategic benefits of vertical integration help ensure that Dr. Reddy’s products are delivered on time. The need for good health continues to propel our business strategies at Dr. Reddy’s. We are in the business of facilitating good health – driven by a companywide imperative to accelerate access to affordable and innovative medicines to people who need them. With this conviction, we continue to invest in product development, acquisitions, and advances in research, processes, and technologies that help us deliver on our promise. We don’t see medicines as just molecules, but as tools that will help people get back to health and promote wellness among them. As we look ahead, we’re committed to meet the needs of consumers by resolving challenges. Our goal is to make good health possible. Important Notice The 2016 Brand-to-Generic-to-Brand Conversion Guide has been produced to provide an easy-to-use reference source of generic names, brand names, and other selected drug information. While the 2016 Brand-to-Generic-to-Brand Conversion Guide is an extensive list, it is not a complete list of allthe generic and brand-name drugs currently available. The 2016 Brand-to-Generic-to-Brand Conversion Guide should not be relied upon in making generic substitution determinations. It is the healthcare professional’s responsibility to consult and follow all applicable federal and state laws and regulations when prescribing or dispensing pharmaceuticals and, as always, the full prescribing information should be consulted. In reaching a professional judgment, healthcare professionals should 5 SEC 1 thoroughly understand the options available for any clinical application, the potential effectiveness of each product, the associated risks and side effects, and possible interactions. This knowledge should be considered in light of the special circumstances of the patient, for each patient is unique. Dr. Reddy’s Laboratories, Inc. does not assume and hereby expressly disclaims any liability whatsoever for any errors or omissions in such information or for any of the products listed. All brand names listed in the “BRAND” columns are trademarks and are the property of their respective owners. To request additional copies, please contact Customer Service at: CUSTOMER SERVICE TELEPHONE 866-733-3952 CUSTOMER SERVICE FAX 866-733-3939 MEDICAL INFORMATION Questions related to: · Medical Inquiries · Product Complaints · Adverse Events TOLL FREE (9:00AM-7:00PM ET) 1-888-375-3784 EMAIL medinfo@drreddys.com 2 Dr. Reddy’s 2016 Product Portfolio SECTION TWO 6 SEC 1 Dr. Reddy’s GenericBrand Dr. Reddy’s GenericBrand A Desloratadine Orally Disintegrating Tablets Allopurinol Tablets, USP Zyloprim® Amlodipine Besylate and Atorvastatin Calcium Tablets Amlodipine Besylate and Benazepril Hydrochloride Capsules Caduet® Lotrel® Amoxicillin and Clavulanate Potassium Extended Release Tablets Augmentin XR® Amoxicillin and Clavulanate Potassium Powder for Oral Suspension Augmentin® Atorvastatin Calcium Tablets Lipitor ® Augmentin® (amoxicillin and clavulanate potassium) Powder for Oral Suspension Augmentin XR ® (amoxicillin and clavulanate potassium) Extended Release Tablets Azacitidine for Injection Augmentin® Augmentin XR® Vidaza® C Ciprofloxacin Tablets, USP Cipro ® Clocortolone Pivalate Cream 0.1% Clopidogrel Tablets USP Cloderm Cream®, 0.1% Plavix ® Divalproex Extended-Release Tablets, USP Docetaxel Injection USP Donepezil Hydrochloride Tablets, 23 mg Dacogen® Esomeprezole Magnesium Delayed-Release Capsules USP Eszolpiclone Tablets CIV SEC 2 Purple text indicates product is available from Dr. Reddy’s Depakote® ER Taxotere® Aricept® Nexium® Delayed-Release Lunesta® F Fenofibrate Capsules, USP Antara® Finasteride Tablets, USP Propecia® Finasteride Tablets, USP Proscar® Fluconazole Tablets, USP Diflucan® Fluoxetine Delayed-Release Capsules USP Prozac® Weekly Arixtra® G Glimepiride Tablets USP 8 Depakote® Sprinkles E Fondaparinux Sodium for Injection D Decitabine for Injection Divalproex Sodium Delayed-Release Capsules USP, (Sprinkle) Clarinex® Reditabs® Purple text indicates product is available from Dr. Reddy’s Amaryl® 9 SEC 2 Dr. Reddy’s GenericBrand Dr. Reddy’s GenericBrand I N Ibandronate Sodium Tablets Boniva® IBU™ Ibuprofen Tablets, USP Motrin® L Lamictal® XR Lansoprazole Delayed-Release Capsules, USP Prevacid® Levalbuterol Inhalation Solution, USP Xopenex® Levofloxacin Tablets Levaquin® M Zyprexa® Zydis Olanzapine Tablets USP Zyprexa® Omeprazole Delayed-Release Capsules, USP Prilosec® Ondansetron Tablets USP Oxaprozin Tablets, USP Zofran® Daypro® P Memantine Hydrochloride Tablets USP Meprobamate Tablets USP CIV Metoprolol Succinate Extended-Release Tablets USP Namenda ® Pantoprazole Sodium Delayed-Release Tablets USP Protonix® Miltown® Pramipexole Dihydrochloride Extended-Release Tablets Mirapex ER® Toprol-XL® Minocycline Hydrochloride Tablets, USP Dynacin® Montelukast Sodium Oral Granules Montelukast Sodium Tablets Singulair Oral Granules ® Singulair® Moxifloxacin Hydrochloride Tablets SEC 2 Starlix® O Olanzapine Orally Disintegrating Tablets Lamotrigine Extended-Release Tablets 10 Nateglinide Tablets USP Avelox® Purple text indicates product is available from Dr. Reddy’s Pravastatin Sodium Tablets, USP Pravachol® Q Quetiapine Fumarate Tablets Seroquel® R Ranitidine Hydrochloride Capsules Zantac® Rivastigmine Tartrate Capsules, USP Exelon® Purple text indicates product is available from Dr. Reddy’s 11 SEC 2 Dr. Reddy’s GenericBrand Ropinirole Extended-Release Tablets Requip XL® S Sirolimus Tablets Rapamune® SSD™ 1% Silver Sulfadiazine Cream SSD™ 1% Silver Sulfadiazine Cream Sumatriptan Injection USP Autoinjection System Imitrex STATdose Pen® Sumatriptan Tablets USP Imitrex® T Tacrolimus Capsules, USP Prograf® Tizanidine Tablets, USP Zanaflex® V Valganciclovir Tablets USP, 450 mg Valcyte® Z Zafirlukast Tablets Accolate® Zenatane™ (Isotretinoin Capsules USP) Ziprasidone Hydrochloride Capsules Accutane® Geodon® Zoledronic Acid Injection Reclast® Zoledronic Acid Injection Zometa® 12 SEC 2 Purple text indicates product is available from Dr. Reddy’s 3 Generic-To-Brand Conversions SECTION THREE GenericBrand A GenericBrand Aldesleukin Abacavir Abacavir Besylate, Lamivudine & Zidovudine Abacavir Sulfate & Lamivudine Abatacept Abiraterone Acetate Ziagen Alendronate Sodium Trizivir Epzicom Alendronate Sodium & Colecalciferol (Vitamin D) Alfuzosin Orencia Alglucosidase Alfa Zytiga Tekamlo Campral Acarbose Precose Aliskiren & HCTZ Acetazolamide Sodium Extended Release Acetohydroxamic Acid Diamox Sequels XR Lithostat Acetylcholine Chloride Miochol-E Acitretin Soriatane Aclidinium Bromide Tudorza Pressair Acrivastine & Pseudoephedrine Semprex-D Acyclovir Zovirax Adalimumab Humira Adapalene Differin Adapalene & Benzoyl Peroxide Epiduo Adefovir Dipivoxil Hepsera Adenosine Adenocard I.V. Ado-Trastuzumab Emtansine Kadcyla Agalsidase Beta Fabrazyme Albendazole Albenza Albuterol Sulfate Proventil HFA Albuterol Sulfate Ventolin Albuterol Sulfate & Ipratropium Bromide Alcaftadine 14 SEC 3 Combivent Lastacaft Purple text indicates product is available from Dr. Reddy’s Uroxatral Lumizyme Tekturna Acamprosate Calcium Sectral Fosamax Fosamax Plus D Aliskiren Aliskiren & Amlodipine Besylate Acebutolol Proleukin Aliskiren & Valsartan Aliskiren, Amlodipine & HCTZ Allopurinol Almotriptan Alogliptin Benzoate & Metformin Alogliptin Benzoate & Pioglitazone Alosetron Alprazolam Alprazolam Extended Release Tekturna HCT Valturna Amturnide Zyloprim Axert Kazano Oseni Lotronex Xanax Xanax XR Alprostadil Caverject Alprostadil Alteplase Prostin VR Pediatric Activase Alteplase Cathflo Activase Altretamine Hexalen Alvimopan Entereg Ambrisentan Letairis Amiodarone Cordarone Amlexanox Aphthasol Amlodipine & Olmesartan Azor Amlodipine Besylate Norvasc Amlodipine Besylate & Atorvastatin Calcium Caduet Purple text indicates product is available from Dr. Reddy’s 15 SEC 3 GenericBrand Amlodipine Besylate & Benazepril Amlodipine Besylate & Telmisartan Amlodipine Besylate, Olmesartan Medoxomil & HCTZ Amoxicillin Amoxicillin & Clavulanate Potassium Lotrel Twynsta Tribenzor Amoxil Augmentin Amoxicillin & Clavulanate Potassium Extended Release Augmentin XR Amoxicillin & Clavulanate Potassium Suspension Amoxicillin For Oral Suspension Augmentin OS Amoxicillin, Clarithromycin & Lansoprazole Ampicillin Sodium & Sulbactam Sodium Amoxil Prevpac Unasyn Anagrelide Agrylin Anakinra Kineret Anastrozole Arimidex Anidulafungin Eraxis Apixaban Eliquis Apraclonidine Aprepitant Arformoterol Tartrate Iopidine Emend Brovana Aripiprazole Abilify Armodafinil Nuvigil Artemether & Lumefantrine Asenapine Maleate Aspirin & Extended Release Dipyridamole Atazanavir Sulfate Coartem Saphris Aggrenox Reyataz Atenolol Tenormin Atenolol & Chlorthalidone Tenoretic Atomoxetine 16 SEC 3 Strattera Purple text indicates product is available from Dr. Reddy’s GenericBrand Atorvastatin Atovaquone Atovaquone & Proguanil Auranofin Axitinib Lipitor Mepron Malarone Ridaura Inlyta Azacitidine Vidaza Azathioprine Imuran Azelaic Acid Azelastine Azelex Astepro Azelastine Astelin Azelastine Optivar Azelastine & Fluticasone Propionate Dymista Azilsartan Kamedoxomil Azilsartan Kamedoxomil & Chlorthalidone Azithromycin Azithromycin Extended Release Aztreonam Edarbi Edarbyclor Zithromax Zmax Azactam B Balsalazide Sodium Becaplermin Beclomethasone Dipropionate Monohydrate Belimumab Benazepril Benazepril & HCTZ Colazal Regranex Beconase AQ Benlysta Lotensin Lotensin HCT Bendamustine Treanda Benzonatate Tessalon Benzphetamine Sodium Bepotastine Besilate Besifloxacin Purple text indicates product is available from Dr. Reddy’s Didrex Bepreve Besivance 17 SEC 3 GenericBrand GenericBrand Betamethasone Celestone Betamethasone Dipropionate Diprolene Betamethasone Dipropionate & Calcipotriene Hydrate Betamethasone Dipropionate & Clotrimazole Betaxolol Suspension Taclonex Betoptic S Buprenorphine & Naloxone Bethanechol Chloride Urecholine Bupropion Lotrisone Bevacizumab Budesonide Suspension Metered Dose Inhaler Bupivacaine Bupivacaine & Marplan Epinephrine Bitartrate Buprenorphine Pulmicort Respules Marcaine Marcaine w/ Epinephrine Buprenex Suboxone Zyban Avastin Bupropion Extended Release Tablets Wellbutrin XL Bexarotene Targretin Bupropion Sustained Release Tablets Wellbutrin SR Bicalutamide Casodex Busulfan Bimatoprost Latisse Bimatoprost Lumigan Bisoprolol Fumarate & Hydrochlorothiazide Bivalirudin Ziac Angiomax Boceprevir Victrelis Bortezomib Velcade Bosentan Tracleer Bosutinib Monohydrate Bosulif Brimonidine Tartrate Alphagan P Brimonidine Tartrate & Brinzolamide Brimonidine Tartrate & Timolol Maleate Simbrinza Combigan Brinzolamide Azopt Bromocriptine Mesylate Parlodel Budesonide Entocort EC Budesonide Rhinocort Aqua Budesonide & Formoterol Fumarate Dihydrate Budesonide Powder Metered Dose Inhaler 18 SEC 3 Symbicort Pulmicort Flexhaler Purple text indicates product is available from Dr. Reddy’s Butabarbital Sodium Butenafine Myleran Butisol Sodium Mentax C Calcipotriene Dovonex Calcitriol Rocaltrol Canagliflozin Invokana Candesartan Atacand Candesartan & HCTZ Capecitabine Atacand HCT Xeloda Carbamazepine Equetro Carbamazepine Tegretol Carbamazepine Extended Release Carbidopa & Levodopa Carbidopa & Levodopa Extended Release Carbidopa, Entacapone & Levodopa Carfilzomib Carisoprodol Carvedilol Carvedilol Phosphate Extended Release Capsule Purple text indicates product is available from Dr. Reddy’s Tegretol-XR Sinemet Sinemet CR Stalevo Kyprolis Soma Coreg Coreg CR 19 SEC 3 GenericBrand Caspofungin Acetate Cefazolin Cefditoren Pivoxil Cefepime Cancidas Ancef Spectracef Maxipime GenericBrand Ciprofloxacin Ciprofloxacin & Hydrocortisone Cisatracurium Citalopram Hydrobromide Cipro Cipro HC Nimbex Celexa Cefixime Suprax Clarithromycin Extended Release Biaxin XL Ceftaroline Fosamil Teflaro Clavulanic Potassium & Ticarcillin Disodium Clindamycin Timentin Ceftazidime Fortaz Ceftibuten Dihydrate Cedax Ceftriaxone Sodium Cefuroxime Axetil Cefuroxime Sodium Celecoxib Rocephin Ceftin Zinacef Celebrex Cephalexin Keflex Certolizumab Pegol Cimzia Cetrorelix Cetrotide Cetuximab Erbitux Cevimeline Evoxac Chlorambucil Chlorothiazide Sodium Chlorzoxazone Cholestyramine Choline Fenofibrate Leukeran Diuril Parafon Forte DSC Questran Trilipix Clobazam Temovate Clocortolone Pivalate Cloderm Clofarabine Anafranil Clonazepam Klonopin Clonidine Clonidine Transdermal Patch Clopidogrel Bisulfate Clorazepate Dipotassium Clozapine Colesevelam Colestipol Colistimethate Sodium Ciclesonide Omnaris Colistin, Hydrocortisone, Neomycin, Thonzonium Suspension Cosyntropin Ciclesonide Zetonna Crizotinib Ciclopirox Loprox Crofelemer Cidofovir Vistide Cromolyn Sodium Cilostazol Cinacalcet 20 SEC 3 Pletal Sensipar Purple text indicates product is available from Dr. Reddy’s Clolar Clomipramine Alvesco Primaxin Onfi Clobetasol Propionate Ciclesonide Cilastatin Sodium, Imipenem Cleocin Crotamiton Cyclopentolate Cycloserine Purple text indicates product is available from Dr. Reddy’s Catapres Catapres TTS Plavix Tranxene Clozaril Welchol Colestid Coly-Mycin M Coly-Mycin S Cortrosyn Xalkori Fulyzaq Gastrocrom Eurax Cyclogyl Seromycin 21 SEC 3 GenericBrand Cyclosporine Neoral Cyclosporine Sandimmune Cystamine Bitartrate Cystagon GenericBrand Desogestrel & Ethinyl Estradiol Desoximetasone Desvenlafaxine Succinate Dexlansoprazole D Ortho-Cept Topicort Pristiq Dexilant Dabigatran Etexilate Mesylate Pradaxa Dexmedetomidine Dabrafenib Mesylate Tafinlar Dexmethylphenidate Extended Release Focalin XR Ampyra Dextroamphetamine Sulfate Dexedrine Dextromethorphan Hydrobromide & Quinidine Sulfate Diazepam Nuedexta Dalfampridine Dalfopristin & Quinupristin Synercid Dalteparin Sodium Fragmin Dantrolene Sodium Dantrium Daptomycin Cubicin Darbepoetin Alfa Aranesp Darifenacin Hydrobromide Enablex Darunavir Ethanolate Prezista Dasatinib Sprycel Decitabine Dacogen Deferasirox Exjade Deferoxamine Mesylate Desferal Degarelix Acetate Firmagon Delavirdine Mesylate Rescriptor Denosumab Prolia Denosumab Xgeva Desflurane Suprane Desloratadine Clarinex Desloratadine & Pseudoephedrine 12 Hour Desloratadine & Pseudoephedrine 24 Hour Desloratadine Orally Disintegrating Tablets Desmopressin Acetate 22 SEC 3 Clarinex-D 12 Hour Clarinex-D 24 Hour Clarinex Reditabs DDAVP Purple text indicates product is available from Dr. Reddy’s Diazoxide Precedex Valium Proglycem Diclofenac & Misoprostol Arthrotec Diclofenac Potassium Cataflam Diclofenac Sodium Voltaren Diclofenac Sodium Extended Release Dicyclomine Voltaren-XR Bentyl Didanosine Videx Didanosine Videx EC Dienogest & Estradiol Valerate Difenoxin & Atropine Natazia Motofen Difluprednate Durezol Digoxin Lanoxin Diltiazem Cardizem Diltiazem Extended Release Dilacor XR Diltiazem Extended Release Capsule Cardizem CD Diltiazem Extended Release Tablet Cardizem LA Dimethyl Fumarate Diphenoxylate & Atropine Dipyridamole Disopyramide Phosphate Purple text indicates product is available from Dr. Reddy’s Tecfidera Lomotil Persantine Norpace 23 SEC 3 GenericBrand Disopyramide Phosphate Extended Release Disulfiram Norpace CR Antabuse Divalproex Sodium Divalproex Sodium Delayed Release Divalproex Sodium Extended Release Docetaxel Depakote Sprinkles Depakote Depakote ER Taxotere Dofetilide Tikosyn Dolasetron Anzemet Donepezil Aricept Doripenem Doribax Dorzolamide Trusopt Dorzolamide & Timolol Maleate Cosopt Doxapram Dopram Doxazosin Extended Release Cardura XL Doxazosin Mesylate Cardura Doxercalciferol Hectorol Doxorubicin Doxil Doxycycline Vibramycin Dronedarone Multaq Drospirenone & Ethinyl Estradiol Yasmin Drospirenone, Ethinyl Estradiol & Levomefolate Calcium Duloxetine Beyaz Dutasteride Dutasteride & Tamsulosin Dyphylline Cymbalta Avodart Jalyn Lufyllin E Eculizumab Efavirenz 24 SEC 3 Soliris Sustiva Purple text indicates product is available from Dr. Reddy’s GenericBrand Efavirenz, Emtricitabine & Tenofovir Disoproxil Fumarate Eletriptan Hydrobromide Eltrombopag Olamine Atripla Relpax Promacta Emtricitabine Emtriva Emtricitabine & Tenofovir Disoproxil Fumarate Emtricitabine, Rilpivirine, Tenofovir & Disoproxil Fumarate Enalapril Maleate Truvada Complera Enalapril Maleate & HCTZ Vaseretic Enfuvirtide Enoxaparin Sodium Entacapone Entecavir Vasotec Fuzeon Lovenox Comtan Baraclude Enzalutamide Xtandi Epinastine Elestat Epirubicin Ellence Eplerenone Inspra Epoprostenol Sodium Eprosartan Eprosartan Mesylate & HCTZ Ergocalciferol Flolan Teveten Teveten HCT Drisdol Eribulin Mesylate Halaven Erlotinib Tarceva Ertapenem Sodium Erythromycin Invanz Ery-Tab Erythromycin Ethylsuccinate E.E.S. Erythromycin Ethylsuccinate Eryped Erythromycin Particle Coated Erythropoietin Alphax Purple text indicates product is available from Dr. Reddy’s PCE Epogen/Procrit 25 SEC 3 GenericBrand Escitalopram Oxalate Esmolol Esomeprazole Magnesium GenericBrand Lexapro Etonogestrel Implanon Brevibloc Etonogestrel Nexplanon Nexium Etravirine Esomeprazole Magnesium & Naproxen Vimovo Everolimus Afinitor Estradiol Climara Everolimus Zortress Exemestane Aromasin Estradiol & Norethindrone Acetate Estradiol Acetate CombiPatch Femtrace Estradiol Acetate Vaginal Ring Femring Estradiol Cypionate Depo-Estradiol Estradiol Valerate Delestrogen Estramustine Phosphate Sodium Estrogens, Conjugated Estrogens, Conjugated & Medroxyprogesterone Acetate Estrogens, Conjugated & Medroxyprogesterone Acetate Eszopiclone Emcyt Ethacrynic Acid Pepcid Uloric Felbamate Felbatol Lunesta Fenofibrate Enbrel Fenofibrate Ortho Evra Ethotoin Etomidate 26 SEC 3 F Febuxostat Ethinyl Estradiol & Norelgestromin Patch Ethinyl Estradiol & Norgestimate Ethosuximide Vytorin Famotidine NuvaRing Ethinyl Estradiol, Norethindrone Acetate & Ferrous Fumarate Ethionamide Zetia Famvir Myambutol Ethinyl Estradiol & Norgestrel Ezetimibe & Simvastatin Bydureon Premphase Ethinyl Estradiol & Etonogestrel Ethinyl Estradiol & Norgestimate Ezetimibe Famciclovir Edecrin Ethambutol Exenatide Synthetic XR Suspension Byetta Premarin Prempro Etanercept Exenatide Synthetic Intelence Ortho Tri-Cyclen Ortho Tri-Cyclen Lo Lo/Ovral-28 Loestrin-Fe Trecator Zarontin Peganone Amidate Purple text indicates product is available from Dr. Reddy’s Fenoldopam Mesylate Fenoprofen Calcium Antara Tricor Corlopam Nalfon Fentanyl Duragesic Fentanyl Citrate Sublimaze Fesoterodine Fumarate Fidaxomicin Filgrastim Toviaz Dificid Neupogen Finasteride Propecia Finasteride Proscar Fingolimod Flecainide Acetate Gilenya Tambocor Fluconazole Diflucan Flucytosine Ancobon Purple text indicates product is available from Dr. Reddy’s 27 SEC 3 GenericBrand Fluocinolone Acetonide Synalar Fluorometholone FML Forte GenericBrand Gadodiamide Omniscan Gadopentetate Dimeglumine Magnevist Efudex Gadoteridol ProHance Fluoxetine Prozac Gadoversetamide Optimark Fluoxetine Sarafem Galantamine Hydrobromide Razadyne Symbyax Galantamine Hydrobromide Extended Release Galsulfase Razadyne ER Fluorouracil Fluoxetine & Olanzapine Fluoxetine Delayed Release Prozac Weekly Flurandrenolide Cream Cordran SP Flurandrenolide Lotion Cordran Flurandrenolide Tape Cordran Tape Fluticasone Furoate Veramyst Fluticasone Propionate Cutivate Fluticasone Propionate MDI Flovent HFA Fluticasone Propionate Spray Flonase Fluticasone Proprionate & Salmeterol Xinafoate Fluvastatin Sodium Advair Lescol Ganciclovir Sodium Gatifloxacin Gemcitibine For Injection Gemfibrozil Gemifloxacin Mesylate Glatiramer Acetate Glimepiride Glipizide Extended Release Glyburide Glyburide & Metformin Naglazyme Cytovene Zymar Gemzar Lopid Factive Copaxone Amaryl Glucotrol XL Diabeta Glucovance Fluvastatin Sodium Extended Release Lescol XL Fondaparinux Sodium For Injection Arixtra Glycopyrrolate Cuvposa Formoterol Fumarate Foradil Glycopyrrolate Robinul Lexiva Golimumab Simponi Goserelin Acetate Zoladex Fosamprenavir Calcium Foscarnet Sodium Foscavir Fosfomycin Tromethamine Monurol Frovatriptan Succinate Fulvestrant Furosemide Frova Faslodex Lasix G Gabapentin Gabapentin Enacarbil Gadobenate Dimeglumine 28 SEC 3 H Halcinonide Halobetasol Propionate Haloperidol Hexachlorophene Neurontin Horizant Multihance Purple text indicates product is available from Dr. Reddy’s Hydrocortisone Hydrocortisone Sodium Succinate Hydroxychloroquine Sulfate Purple text indicates product is available from Dr. Reddy’s Halog Ultravate Haldol Phisohex Cortef Solu-Cortef Plaquenil 29 SEC 3 GenericBrand GenericBrand Hydroxyurea Hydrea Insulin Lispro Recombinant Humalog Pen Hydroxyzine Vistaril Insulin Lispro Recombinant & Insulin Lispro Protamine Recombinant Insulin Lispro Recombinant & Insulin Lispro Protamine Recombinant Humalog Mix 75/25 Humalog Mix 75/25 Pen I Ibandronate Sodium Boniva Ibuprofen Advil Insulin Recombinant Human Humulin R Ibuprofen Motrin Insulin Recombinant Human Novolin R Corvert Insulin Recombinant Human & Insulin Suspension Isophane Recombinant Human Ibutilide Fumarate Icosapent Ethyl Vascepa Idarubicin Idamycin Iloperidone Fanapt Iloprost Ventavis Imatinib Mesylate Gleevec Imiglucerase Cerezyme Imipramine Tofranil Imiquimod Zyclara Immune Globulin Cytogam Indacaterol Arcapta Neohaler Indinavir Sulfate Crixivan Indomethacin Indocin Infliximab Remicade Ingenol Mebutate Picato Insulin Aspart Recombinant Novolog Insulin Aspart Recombinant+Insulin Aspart Protamine Recombinant Novolog Mix 70/30 Insulin Recombinant Human, Insulin Suspension Isophane Recombinant Human Insulin Suspension Isophane Recombinant Human Insulin Suspension Isophane Recombinant Human Interferon Alfa-2B Iodixanol Iohexol Isovue Iopromide Ultravist Iothalamic Sodium Conray Ipilimumab Yervoy Ipratropium Bromide Irbesartan Apidra Irinotecan SEC 3 Visipaque Omnipaque Iopamidol Irbesartan & HCTZ Purple text indicates product is available from Dr. Reddy’s Intron-A Avonex Lantus 30 Humulin N Betaseron Insulin Glargine Recombinant Humalog Mix 50/50 Humalog Novolin N Interferon Beta-1B Levemir Insulin Lispro Protamine Recombinant & Insulin Lispro Recombinant Insulin Lispro Recombinant Novolin 70/30 Interferon Beta-1A Insulin Detemir Recombinant Insulin Glulisine Humulin 70/30 Iron Sucrose Isoflurane Isoniazid & Rifampin Purple text indicates product is available from Dr. Reddy’s Atrovent Avapro Avalide Camptosar Venofer Forane Rifamate 31 SEC 3 GenericBrand Isosorbide Dinitrate Isordil GenericBrand Levocarnitine Isotretinoin Accutane Levocarnitine Sugar-Free Isotretinoin Zenatane Levocetirizine Dihydrochloride Isradipine Extended Release Dynacirc CR Itraconazole Ivacaftor Levofloxacin Sporanox Levoleucovorin Calcium Kalydeco Levonorgestrel Carnitor Carnitor SF Xyzal Levaquin Fusilev Plan B One Step Ivermectin Stromectol Levonorgestrel & Ethinyl Estradiol Ixabepilone Ixempra Kit Levothyroxine Sodium Synthroid Lidocaine Xylocaine K Ketamine Ketoconazole Ketalar Linaclotide Linzess Nizoral Shampoo Linagliptin Tradjenta Linagliptin & Metformin L Lacosamide Vimpat Lamivudine Epivir Lamivudine & Zidovudine Combivir Lamotrigine Chewable Tablets Lamotrigine Extended Release Nordette Lincomycin Linezolid Liothyronine Sodium Lamictal CD Liraglutide Recombinant Lamictal XR Lisdexamfetamine Dimesylate Jentadueto Lincocin Zyvox Cytomel Victoza Vyvanse Lamictal Lisinopril Prinivil Lansoprazole Prevacid Lisinopril Zestril Lanthanum Carbonate Fosrenol Lamotrigine Tablets Lapatinib Ditosylate Tykerb Laronidase Aldurazyme Latanoprost Xalatan Lenalidomide Revlimid Letrozole Femara Leuprolide Acetate Lupron Depot Levalbuterol Inhalation Solution Levalbuterol MDI Levetiracetam Levobunolol 32 SEC 3 Xopenex Xopenex HFA Keppra Betagan Purple text indicates product is available 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Restoril Temodar Temsirolimus Torisel Tenofovir Disoproxil Fumarate Viread Terbinafine Lamisil Terconazole Terazol 3 Terconazole Terazol 7 Teriflunomide Aubagio Teriparatide Recombinant Human Forteo Tesamorelin Acetate Egrifta Testosterone Cypionate Tetrabenazine Theophylline DepoTestosterone Xenazine Elixophyllin Tiagabine Gabitril Ticagrelor Brilinta Tygacil Protopic Betimol Adcirca Timolol Tacrolimus 44 Telmisartan & HCTZ Timolol Prograf Tadalafil Telmisartan Ketek Tigecycline Tacrolimus Tadalafil Telithromycin Nucynta ER Cialis Purple text indicates product is available from Dr. Reddy’s Timolol Extended Release Purple text indicates product is available from Dr. Reddy’s Timoptic Timoptic-XE 45 SEC 3 GenericBrand Tinidazole Tindamax GenericBrand Triamterene & HCTZ Dyazide Tiopronin Thiola Triazolam Halcion Tiotropium Bromide Monohydrate Spiriva Trientine Syprine Tipranavir Aptivus Tizanidine Zanaflex Tobramycin MDI Tobi Podhaler Tocilizumab Actemra Trimethobenzamide Trimipramine Triptorelin Pamoate Tropicamide Tofacitinib Citrate Xeljanz Trospium Chloride Tolcapone Tasmar Trospium Chloride Extended Release Tolterodine Tartrate Detrol Tolterodine Tartrate Extended Release Tolvaptan Detrol LA Samsca Topiramate Topamax Topotecan Hycamtin Toremifene Citrate Torsemide Tramadol Tramadol & Acetaminophen Trandolapril Trandolapril & Verapamil Tranexamic Acid Tranylcypromine Sulfate Trastuzumab Fareston Demadex Ultram Ultracet Ella Actigall Ustekinumab Stelara V Valacyclovir Valganciclovir Valproic Acid Capsule Valproic Sodium Injection Tarka Valsartan & Amlodipine Besylate Parnate Sanctura Sanctura XR Ursodiol Valsartan Herceptin Trelstar Mydriacyl U Ulipristal Acetate Mavik Cyklokapron Tigan Surmontil Valsartan & HCTZ Valsartan, Amlodipine Besylate & HCTZ Vancomycin Valtrex Valcyte Depakene Depacon Diovan Exforge Diovan HCT Exforge HCT Vancocin Travoprost Travatan Z Vardenafil Levitra Treprostinil Remodulin Vardenafil Staxyn Treprostinil Sodium Tyvaso Varenicline 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indicates product is available from Dr. Reddy’s Brand Generic A Abilify Aripiprazole Abraxane Paclitaxel Accolate Zafirlukast Accupril Quinapril Brand Generic Alimta Pemetrexed Alinia Nitazoxanide Alkeran Melphalan Alocril Nedocromil Alomide Lodoxamide Accuretic Quinapril & HCTZ Accutane Isotretinoin Alrex Aceon Perindopril Altabax Alphagan P Brimonidine Tartrate Loteprednol Etabonate Retapamulin Aciphex Rabeprazole Sodium Actemra Tocilizumab Alvesco Ciclesonide Actigall Ursodiol Amaryl Glimepiride Activase Alteplase Ambien Zolpidem Tartrate Ambien CR Zolpidem Tartrate Extended Release Naratriptan Actonel Actoplus Met Actoplus Met XR Actos Adalat CC Adcirca Adenocard I.V. Advair Advicor Advil Afinitor Aggrenox Agrylin Albenza Aldactazide Aldactone Aldurazyme 50 SEC 4 Risedronate Sodium Pioglitazone & Metformin Pioglitazone & Metformin, Extended Release Pioglitazone Altace Amerge Amidate Amitiza Ramipril Etomidate Lubiprostone Nifedipine Extended Release Amoxil Amoxicillin Tadalafil Amoxil Amoxicillin For Oral Suspension Adenosine Fluticasone Proprionate & Salmeterol Xinafoate Lovastatin & Niacin Ibuprofen Everolimus Aspirin & Extended Release Dipyridamole Anagrelide Albendazole Spironolactone & HCTZ Spironolactone Laronidase Purple text indicates product is available from Dr. Reddy’s Ampyra Dalfampridine Amturnide Aliskiren, Amlodipine & HCTZ Anadrol-50 Oxymetholone Anafranil Clomipramine Anaprox Naproxen Sodium Ancef Cefazolin Ancobon Flucytosine Angiomax Bivalirudin Antabuse Antara Disulfiram Fenofibrate Anzemet Dolasetron Aphthasol Amlexanox Purple text indicates product is available from Dr. Reddy’s 51 SEC 4 Brand Generic Apidra Insulin Glulisine 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Meperidine Demser Metyrosine Denavir Penciclovir Sodium Depacon Valproic Sodium Injection Depakene Valproic Acid Capsule Depakote Divalproex Sodium Delayed Release Divalproex Sodium Extended Release Divalproex Sodium Depakote ER Depakote Sprinkles Depo-Estradiol Depo-Medrol 58 SEC 4 Prednicarbate Deferoxamine Mesylate Desoxyn Methamphetamine Detrol Tolterodine Tartrate Detrol LA Tolterodine Tartrate Extended Release Dexedrine Dexilant Diabeta Diamox Sequels XR Dibenzyline Didrex Differin Dificid Diflucan Dilacor XR Dextroamphetamine Sulfate Dexlansoprazole Glyburide Acetazolamide Sodium Extended Release Phenoxybenzamine Benzphetamine Sodium Adapalene Fidaxomicin Fluconazole Diltiazem Extended Release Dilantin Phenytoin Sodium Diovan Valsartan Diovan HCT Valsartan & HCTZ Dipentum Olsalazine Sodium Diprivan Propofol Diprolene Betamethasone Dipropionate Ditropan XL Oxybutynin Extended Release Diuril Chlorothiazide Sodium Estradiol Cypionate Dopram Doral Doxapram Quazepam Methylprednisolone Doribax Doripenem Purple text indicates product is available from Dr. Reddy’s Purple text indicates product is available from Dr. Reddy’s 59 SEC 4 Brand Dovonex Doxil Drisdol Duetact Dulera Duragesic Durezol Dutoprol Generic Brand Calcipotriene Eliquis Doxorubicin Elitek Ergocalciferol Pioglitazone & Glimepiride Mometasone Furoate & Formoterol Fumarate Dihydrate Fentanyl Difluprednate Metoprolol Succinate & HCTZ Generic Apixaban Rasburicase Elixophyllin Theophylline Ella Ulipristal Acetate Ellence Epirubicin Elmiron Pentosan Polysulfate Sodium Elocon Mometasone Furoate Eloxatin Oxaliplatin Emcyt Estramustine Phosphate Sodium Emend Aprepitant Emsam Selegiline Dyazide Triamterene & HCTZ Dymista Azelastine & Fluticasone Propionate Dynacin Minocycline Emtriva Emtricitabine Isradipine Extended Release Enablex Darifenacin Hydrobromide Dynacirc CR Dyrenium Triamterene E EC-Naprosyn Edarbi Edarbyclor Naproxen Sodium Enteric Coated Azilsartan Kamedoxomil Edecrin Azilsartan Kamedoxomil & Chlorthalidone Ethacrynic Acid Edurant Rilpivirine E.E.S. Effexor Effexor XR Effient Erythromycin Ethylsuccinate Venlafaxine Venlafaxine Extended Release Prasugrel Efudex Fluorouracil Egrifta Tesamorelin Acetate Eldepryl Elestat Elidel 60 SEC 4 Selegiline Epinastine Pimecrolimus Purple text indicates product is available from Dr. Reddy’s Enbrel Etanercept Entereg Alvimopan Entocort EC Epiduo Epivir Epogen/Procrit Budesonide Adapalene & Benzoyl Peroxide Lamivudine Erythropoietin Alpha Epzicom Abacavir Sulfate & Lamivudine Equetro Carbamazepine Eraxis Erbitux Erivedge Anidulafungin Cetuximab Vismodegib Ertaczo Sertaconazole Nitrate Eryped Erythromycin Ethylsuccinate Ery-Tab Erythromycin Eurax Crotamiton Evista Raloxifene Evoxac Cevimeline Purple text indicates product is available from Dr. Reddy’s 61 SEC 4 Brand Exelderm Generic Sulconazole Nitrate Exelon Rivastigmine Tartrate Exforge Valsartan & Amlodipine Besylate Exforge HCT Exjade Valsartan, Amlodipine Besylate & HCTZ Deferasirox Fosamax Fosamax Plus D Agalsidase Beta Generic Alendronate Sodium Foscavir Alendronate Sodium & Colecalciferol (Vitamin D) Foscarnet Sodium Fosrenol Lanthanum Carbonate Fragmin Frova F Fabrazyme Brand Fulyzaq Furadantin Dalteparin Sodium Frovatriptan Succinate Crofelemer Nitrofurantoin Factive Gemifloxacin Mesylate Famvir Famciclovir Fusilev Levoleucovorin Calcium Iloperidone Fuzeon Enfuvirtide Fanapt G Fareston Toremifene Citrate Faslodex Fulvestrant Gabitril Felbatol Felbamate Gastrocrom Feldene Piroxicam Gemzar Gemcitibine For Injection Femara Letrozole Geodon Ziprasidone Femring Tiagabine Cromolyn Sodium Estradiol Acetate Vaginal Ring Gilenya Fingolimod Femtrace Estradiol Acetate Gleevec Imatinib Mesylate Firmagon Degarelix Acetate Glucophage Metformin Flagyl ER Metronidazole Glucotrol XL Glipizide Extended Release Epoprostenol Sodium Glucovance Glyburide & Metformin Flolan Flomax Tamsulosin Flonase Fluticasone Propionate Spray Flovent HFA Glyset Miglitol H Fluticasone Propionate MDI Halaven Eribulin Mesylate FML Forte Fluorometholone Halcion Triazolam Focalin XR Foradil Dexmethylphenidate Extended Release Formoterol Fumarate Forane Isoflurane Fortaz Ceftazidime Forteo Teriparatide Recombinant Human 62 SEC 4 Purple text indicates product is available from Dr. Reddy’s Haldol Haloperidol Halog Halcinonide Hectorol Doxercalciferol Hepsera Adefovir Dipivoxil Herceptin Purple text indicates product is available from Dr. Reddy’s Trastuzumab 63 SEC 4 Brand Hexalen Hiprex Horizant Humalog Generic Altretamine Methenamine Hippurate Gabapentin Enacarbil Brand Generic Increlex Mecasermin Recombinant Inderal LA Propranolol Extended Release Indocin Indomethacin Insulin Lispro Recombinant Inlyta Axitinib Humalog Mix 50/50 Insulin Lispro Protamine Recombinant & Insulin Lispro Recombinant Inspra Eplerenone Humalog Mix 75/25 Insulin Lispro Recombinant & Insulin Lispro Protamine Recombinant Insulin Lispro Recombinant & Insulin Lispro Protamine Recombinant Insulin Lispro Recombinant Humalog Mix 75/25 Pen Humalog Pen Humira Humulin 70/30 Humulin N Humulin R Hycamtin Adalimumab Insulin Recombinant Human & Insulin Suspension Isophane Recombinant Human Insulin Suspension Isophane Recombinant Human Insulin Recombinant Human Intelence Etravirine Intron-A Interferon Alfa-2B Invanz Ertapenem Sodium Invega Paliperidone Invirase Saquinavir Mesylate Invokana Canagliflozin Iopidine Apraclonidine Isentress Raltegravir Potassium Isordil Isosorbide Dinitrate Isovue Iopamidol Ixempra Kit Ixabepilone J Topotecan Jakafi Ruxolitinib Phosphate Hydrea Hydroxyurea Jalyn Dutasteride & Tamsulosin Hyzaar Losartan & HCTZ I Iclusig Idamycin Ilevro Imitrex Imitrex STATdose Pen Implanon Sitagliptin Ponatinib Jentadueto Linagliptin & Metformin Idarubicin Juvisync Simvastatin & Sitagliptin Nepafenac K Sumatriptan Succinate Kadcyla Sumatriptan Injection Kaletra Etonogestrel Azathioprine Incivek Telaprevir SEC 4 Sitagliptin & Metformin Januvia Imuran 64 Janumet Purple text indicates product is available from Dr. Reddy’s Ado-Trastuzumab 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Lufyllin Lumigan Lumizyme Lunesta Lupron Depot Lyrica Lysodren Generic Dyphylline Brand Methergine Bimatoprost Mevacor Lovastatin Micardis Telmisartan Eszopiclone Leuprolide Acetate Pregabalin Mitotane Micardis HCT Miltown Minipress Minocin Miochol-E Macrobid Nitrofurantoin, Macrocrystalline Mirapex Macrodantin Nitrofurantoin, Macrocrystalline Mirapex ER Gadopentetate Dimeglumine Malarone Atovaquone & Proguanil Marcaine Bupivacaine Marcaine w/ Epinephrine Marplan Mavik Maxair Autohaler Maxalt Maxalt-MLT Maxipime Medrol Megace ES Mentax Mephyton Bupivacaine & Marplan Epinephrine Bitartrate Isocarboxazid Trandolapril Pirbuterol Acetate Rizatriptan Rizatriptan Orally Disintegrating Tablet Cefepime Methylprednisolone Megestrol Acetate Butenafine Phytonadione Mobic Modicon Monistat 3 Multaq Multihance Myambutol Mycamine Mycobutin Mydriacyl Ibuprofen Dronedarone Gadobenate Dimeglumine Ethambutol Micafungin Sodium Rifabutin Tropicamide Mycophenolic Acid Busulfan Myrbetriq Meropenem N SEC 4 Norethindrone & Ethinyl Estradiol Miconazole Nitrate Myleran Merrem IV Purple text indicates product is available from Dr. Reddy’s Pramipexole Dihydrochloride Extended-Release Meloxicam Myfortic Sibutramine 68 Acetylcholine Chloride Pramipexole Dihydrochloride Difenoxin & Atropine Motrin Meridia Pyridostigmine Bromide Prazosin Minocycline Motofen Mysoline Mestinon Meprobamate Fosfomycin Tromethamine Atovaquone Mesna Telmisartan & HCTZ Monurol Mepron Mesnex Methylergonovine Maleate Alglucosidase Alfa M Magnevist Generic Naftin Naglazyme Purple text indicates product is available from Dr. Reddy’s Mirabegron Primidone Naftifine Galsulfase 69 SEC 4 Brand Generic Brand Nalfon Fenoprofen Calcium Norvir Namenda Namenda XR Naprosyn Nardil Memantine Naproxen Phenelzine Sulfate Ropivacaine Nasonex Mometasone Furoate Monohydrate Natacyn Natamycin Natazia Dienogest & Estradiol Valerate Natroba Spinosad Neoral Neptazane Neulasta Ritonavir Novolin 70/30 Insulin Recombinant Human, Insulin Suspension Isophane Recombinant Human Memantine Extended Release Naropin Navelbine Generic Vinorelbine Tartrate Cyclosporine Methazolamide Pegfilgrastim Novolin N Insulin Suspension Isophane Recombinant Human Novolin R Insulin Recombinant Human Novolog Insulin Aspart Recombinant Novolog Mix 70/30 Insulin Aspart Recombinant+Insulin Aspart Protamine Recombinant Noxafil Posaconazole NPlate Romiplostim Nucynta Tapentadol Nucynta ER Nuedexta Tapentadol Extended Release Dextromethorphan Hydrobromide & Quinidine Sulfate Ethinyl Estradiol & Etonogestrel Neupogen Filgrastim NuvaRing Neupro Rotigotine Nuvigil Armodafinil Nymalize Nimodipine Neurontin Gabapentin Nevanac Nepafenac Nexavar Sorafenib Tosylate Nexium Esomeprazole Magnesium Nexplanon Nilandron O Omnaris Omnipaque Omniscan Gadodiamide Nilutamide Oncaspar Pegaspargase Cisatracurium Onfi Nizoral Shampoo Ketoconazole Onglyza Noroxin Norpace Norpace CR Norvasc 70 SEC 4 Iohexol Etonogestrel Nimbex Nordette Ciclesonide Levonorgestrel & Ethinyl Estradiol Clobazam Saxagliptin Opana Oxymorphone Norfloxacin Opana ER Oxymorphone Extended Release Disopyramide Phosphate Optimark Gadoversetamide Disopyramide Phosphate Extended Release Amlodipine Besylate Purple text indicates product is available from Dr. Reddy’s Optivar Orap Purple text indicates product is available from Dr. Reddy’s Azelastine Pimozide 71 SEC 4 Brand Orencia Ortho-Cept Ortho-Cyclen Ortho Evra Ortho Micronor Generic Brand Abatacept Pepcid Desogestrel & Ethinyl Estradiol Percocet Oxycodone & Acetaminophen Percodan Oxycodone & Aspirin Ethinyl Estradiol & Norelgestromin Patch Norethindrone Norethindrone & Ethinyl Estradiol Ortho-Novum 7/7/7 Norethindrone & Ethinyl Estradiol Ortho Tri-Cyclen Ethinyl Estradiol & Norgestimate Ortho Tri-Cyclen Lo Ethinyl Estradiol & Norgestimate Alogliptin Benzoate & Pioglitazone Osphena Ospemifene Oxandrin Oxandrolone Oxistat Oxsoralen Ultra Oxycontin Oxiconazole Nitrate Methoxsalen Oxycodone Extended Release P Pamelor Parafon Forte DSC Nortriptyline Chlorzoxazone Parlodel Bromocriptine Mesylate Parnate Tranylcypromine Sulfate Pataday Olopatadine Ophthalmic Solution Patanase Patanol Paxil Olopatadine Nasal Spray Olopatadine Ophthalmic Solution Paroxetine Paxil CR Paroxetine Extended Release PCE Erythromycin Particle Coated Peganone Pegasys Pentam-300 72 SEC 4 Famotidine Norgestimate & Ethinyl Estradiol Ortho-Novum 1/35 Oseni Generic Ethotoin Peginterferon Alfa-2A Pentamidine Isethionate Purple text indicates product is available from Dr. Reddy’s Perjeta Persantine Phenergan Pertuzumab Dipyridamole Promethazine Phisohex Hexachlorophene Picato Ingenol Mebutate Pitocin Oxytocin Plan B One Step Plaquenil Plavix Pletal Pomalyst Ponstel Potiga Pradaxa PrandiMet Prandin Pravachol Precedex Precose Prefest Premarin Levonorgestrel Hydroxychloroquine Sulfate Clopidogrel Bisulfate Cilostazol Pomalidomide Mefenamic Acid Retigabine Dabigatran Etexilate Mesylate Repaglinide & Metformin Repaglinide Pravastatin Sodium Dexmedetomidine 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Finasteride Alprostadil Remicade Pantoprazole Tacrolimus Albuterol Sulfate Provera Medroxyprogesterone Acetate Provigil Modafinil Prozac Fluoxetine Pulmicort Flexhaler Pulmicort Respules Purinethol 74 SEC 4 Fluoxetine Delayed Release Budesonide Powder Metered Dose Inhaler Budesonide Suspension Metered Dose Inhaler Mercaptopurine Purple text indicates product is available from Dr. Reddy’s Becaplermin Relenza Finasteride Prozac Weekly Ranolazine Rapaflo Proscar Prostin VR Pediatric Protonix Proventil HFA Cholestyramine R Ranexa Propecia Protopic Generic Remodulin Eletriptan Hydrobromide Mirtazapine Mirtazapine Orally Disintegrating Tablet Infliximab Treprostinil Renagel Sevelamer Renvela Sevelamer Carbonate Requip Ropinirole Requip XL Ropinirole Extended Release Rescriptor Delavirdine Mesylate Restoril Temazepam Retin-A Tretinoin Retin-A Micro Retrovir Revatio Revlimid Purple text indicates product is available from Dr. Reddy’s Tretinoin Zidovudine Sildenafil Lenalidomide 75 SEC 4 Brand Reyataz Rhinocort Aqua Ridaura Rifadin Rifamate Rilutek Risperdal M-Tab Ritalin Ritalin LA Generic Brand Atazanavir Sulfate Sectral Budesonide Auranofin Rifampin Isoniazid & Rifampin Riluzole Risperidone Orally Disintegrating Tablets Methylphenidate Rituxan Methylphenidate Extended Release Capsule Methylphenidate Extended Release Tablet Rituximab Robaxin Methocarbamol Robinul Glycopyrrolate Ritalin-SR Rocaltrol Calcitriol Rocephin Ceftriaxone Sodium Rozerem Ramelteon Rythmol Propafenone Rythmol SR Propafenone Extended Release S Sabril Samsca Generic Acebutolol Selzentry Maraviroc Semprex-D Acrivastine & Pseudoephedrine Sensipar Cinacalcet Serevent Diskus Seromycin Salmeterol Xinafoate Metered Dose Inhaler Cycloserine Seroquel Quetiapine Fumarate Seroquel XR Quetiapine Fumarate Extended Release Mesalamine SF Rowasa Silvadene Silver Sulfadiazine Simbrinza Brimonidine Tartrate & Brinzolamide Simponi Sinemet Golimumab Carbidopa & Levodopa Sinemet CR Carbidopa & Levodopa Extended Release Montelukast Sodium Singulair Singulair Chewable Singulair Oral Granules Skelaxin Vigabatrin Soliris Tolvaptan Solu-Cortef Montelukast Sodium Chewable Montelukast Sodium Oral Granules Metaxalone Eculizumab Hydrocortisone Sodium Succinate Sanctura Trospium Chloride Solu-Medrol Sanctura XR Soma Sandimmune Trospium Chloride Extended Release Cyclosporine Sandostatin Octreotide Acetate Sonata Zaleplon Saphris Asenapine Maleate Soriatane Acitretin Sarafem Savella 76 SEC 4 Fluoxetine Milnacipran Purple text indicates product is available from Dr. Reddy’s Methylprednisolone Sodium Succinate Carisoprodol Somavert Pegvisomant Spectracef Spiriva Cefditoren Pivoxil Tiotropium Bromide Monohydrate Purple text indicates product is available from Dr. Reddy’s 77 SEC 4 Brand Sporanox Sprycel SSD Stalevo Generic Itraconazole Dasatinib Silver Sulfadiazine Carbidopa, Entacapone & Levodopa Starlix Nateglinide Staxyn Vardenafil Stelara Ustekinumab Stivarga Regorafenib Strattera Stromectol Brand Tafinlar Dabrafenib Mesylate Talwin Pentazocine Lactate Tambocor Tamiflu Tarceva Tolcapone Taxotere Docetaxel Tazorac Nisoldipine Suprane Desflurane Teflaro Cefixime Trimipramine Tegretol-XR Sustiva Efavirenz Sutent Sunitinib Malate Tekturna Budesonide & Formoterol Fumarate Dihydrate Fluoxetine & Olanzapine Pramlintide Acetate Synagis Palivizumab Synalar Fluocinolone Acetonide Syprine Dalfopristin & Quinupristin Levothyroxine Sodium Trientine T Taclonex 78 SEC 4 Betamethasone Dipropionate & Calcipotriene Hydrate Purple text indicates product is available from Dr. Reddy’s Tazarotene Tegretol Tekamlo Synthroid Trandolapril & Verapamil Tasmar Sular Synercid Bexarotene Tarka Tecfidera Symlin Erlotinib Targretin Ivermectin Buprenorphine & Naloxone Symbyax Methimazole Nilotinib Suboxone Symbicort Oseltamavir Phosphate Tapazole Atomoxetine Fentanyl Citrate Surmontil Flecainide Acetate Tasigna Sublimaze Suprax Generic Dimethyl Fumarate Ceftaroline Fosamil Carbamazepine Carbamazepine Extended Release Tekturna HCT Temodar Aliskiren & Amlodipine Besylate Aliskiren Aliskiren & HCTZ Temozolomide Temovate Clobetasol Propionate Tenoretic Atenolol & Chlorthalidone Tenormin Atenolol Terazol 3 Terconazole Terazol 7 Terconazole Tessalon Benzonatate Teveten Eprosartan Teveten HCT Eprosartan Mesylate & HCTZ Thiola Tiopronin Tigan Trimethobenzamide Purple text indicates product is available from Dr. Reddy’s 79 SEC 4 Brand Tikosyn Timentin Timoptic Timoptic-XE Generic Dofetilide Clavulanic Potassium & Ticarcillin Disodium Timolol Brand Truvada Tudorza Pressair Twynsta Generic Emtricitabine & Tenofovir Disoproxil Fumarate Aclidinium Bromide Amlodipine Besylate & Telmisartan Timolol Extended Release Tygacil Tigecycline Tinidazole Tykerb Lapatinib Ditosylate Tobramycin MDI Tysabri Natalizumab Tofranil Imipramine Tyvaso Treprostinil Sodium Topamax Topiramate Tyzeka Telbivudine Tindamax Tobi Podhaler Topicort Toprol-XL Desoximetasone Torisel Metoprolol Succinate Extended Release Temsirolimus Toviaz Fesoterodine Fumarate U Uloric Febuxostat Ultane Sevoflurane Ultiva Tracleer Bosentan Ultracet Tradjenta Linagliptin Ultram Transderm Scop Tranxene Scopolamine Clorazepate Dipotassium Ultravate Ultravist Travoprost Unasyn Treanda Bendamustine Trecator Ethionamide Uniretic Travatan Z Trelstar Treximet Tribenzor Tricor Trileptal Triptorelin Pamoate Sumatriptan Succinate & Naproxen Sodium Amlodipine Besylate, Olmesartan Medoxomil & HCTZ Fenofibrate Oxcarbazepine Trilipix Choline Fenofibrate Trizivir Abacavir Besylate, Lamivudine & Zidovudine Dorzolamide Trusopt 80 SEC 4 Purple text indicates product is available from Dr. Reddy’s Univasc Urecholine Uroxatral Remifentanil Tramadol & Acetaminophen Tramadol Halobetasol Propionate Iopromide Ampicillin Sodium & Sulbactam Sodium Moexipril & HCTZ Moexipril Bethanechol Chloride Alfuzosin V Valcyte Valganciclovir Valium Diazepam Valtrex Valacyclovir Valturna Vancocin Vascepa Purple text indicates product is available from Dr. Reddy’s Aliskiren & Valsartan Vancomycin Icosapent Ethyl 81 SEC 4 Brand Vaseretic Generic Enalapril Maleate & HCTZ Vasotec Enalapril Maleate Vectibix Panitumumab Velcade Bortezomib Venofer Iron Sucrose Ventavis Iloprost Ventolin Albuterol Sulfate Veramyst Vesicare Fluticasone Furoate Solifenacin Succinate Brand Vivactil Diclofenac Sodium Voltaren-XR Diclofenac Sodium Extended Release Pazopanib Votrient Vytorin W Vfend Voriconazole Vfend IV Voriconazole Wellbutrin XL Victoza Lisdexamfetamine Dimesylate Welchol Wellbutrin SR Vibramycin Ezetimibe & Simvastatin Vyvanse Rimeloxone Sildenafil Citrate Protriptyline Voltaren Vexol Viagra Generic Colesevelam Bupropion Sustained Release Tablets Bupropion Extended Release Tablets X Doxycycline Xalatan Liraglutide Recombinant Xalkori Latanoprost Crizotinib Victrelis Boceprevir Vidaza Azacitidine Xanax Xanax XR Videx Didanosine Xarelto Rivaroxaban Videx EC Didanosine Xeljanz Tofacitinib Citrate Viibryd Vilazodone Xeloda Capecitabine Vimovo Esomeprazole Magnesium & Naproxen Lacosamide Vimpat Viracept Viramune Viramune XR Viread Visipaque Nelfinavir Mesylate Nevirapine Nevirapine Extended Release Tenofovir Disoproxil Fumarate Iodixanol Vistaril Hydroxyzine Vistide Cidofovir 82 SEC 4 Purple text indicates product is available from Dr. Reddy’s Alprazolam Alprazolam Extended Release Xenazine Tetrabenazine Xenical Orlistat Xgeva Denosumab Xifaxan Rifaximin Xolair Xopenex Omalizumab Levalbuterol Inhalation Solution Xopenex HFA Xtandi Xylocaine Xyzal Purple text indicates product is available from Dr. Reddy’s Levalbuterol MDI Enzalutamide Lidocaine Levocetirizine Dihydrochloride 83 SEC 4 Brand Generic Zoladex Y Yasmin Drospirenone & Ethinyl Estradiol Yervoy Ipilimumab Ziv-Aflibercept Zanaflex Tizanidine Zantac Ranitidine Zarontin Zaroxolyn Ethosuximide Metolazone Zavesca Miglustat Zegerid Magnesium Hydroxide, Omeprazole & Sodium Bicarbonate Zelboraf Vemurafenib Zemplar Paricalcitol Zemuron Rocuronium Bromide Zenatane Isotretinoin Zerit Zestoretic Zestril Zetia Zetonna Ziac Stavudine Lisinopril & HCTZ Lisinopril Ezetimibe Ciclesonide Bisoprolol Fumarate & Hydrochlorothiazide Ziagen Abacavir Zinacef Cefuroxime Sodium Zioptan Zithromax Azithromycin Extended Release Simvastatin SEC 4 Goserelin Acetate Vorinostat Sertraline Zoledronic Acid Injection Zomig Zolmitriptan Zonegran Zonisamide Zortress Zosyn Zovirax Everolimus Piperacillin Sodium & Tazobactam Sodium Acyclovir Zyban Bupropion Zyclara Imiquimod Zyflo Zyflo CR Zylet Zyloprim Zymar Zyprexa Zyprexa Zydis Zileuton Zileuton Extended Release Loteprednol Etabonate & Tobramycin Allopurinol Gatifloxacin Olanzapine Zytiga Olanzapine Orally Disintegrating Tablets Abiraterone Acetate Zyvox Linezolid Tafluprost Zocor 84 Zoloft Generic Azithromycin Zmax Zofran Zolinza Zometa Z Zaltrap Brand Ondansetron Purple text indicates product is available from Dr. Reddy’s Purple text indicates product is available from Dr. Reddy’s 85 SEC 4 Lists ISMP’s List of Error-Prone Abbreviations, Symbols, and Dose Designations The abbreviations, symbols, and dose designations found in this table have been reported to ISMP through the ISMP National Medication Errors Reporting Program (ISMP MERP) as being frequently misinterpreted and involved in harmful medication errors. They should NEVER be used when communicating medical information. This includes internal communications, telephone/ verbal prescriptions, computer-generated labels, labels for drug storage bins, medication administration records, as well as pharmacy and prescriber computer order entry screens. 5 Clinical Resources SECTION FIVE ABBREVIATIONS INTENDED MEANING MISINTERPRETATION CORRECTION µg Microgram Mistaken as “mg” Use “mcg” AD, AS, AU Right ear, left ear, each ear Mistaken as OD, OS, OU (right eye, left eye, each eye) Use “right ear,” “left ear,” or “each ear” OD, OS, OU Right eye, left eye, each eye Mistaken as AD, AS, Use “right eye,” AU (right ear, left ear, “left eye,” or each ear) “each eye” BT Bedtime Mistaken as “BID” (twice daily) Use “bedtime” cc Cubic centimeters Mistaken as “u” (units) Use “mL” D/C Discharge or discontinue IJ Injection Mistaken as “IV” or “intrajugular” Use “injection” IN Intranasal Mistaken as “IM” or “IV” Use “intranasal” or “NAS” HS Half-strength Mistaken as bedtime Use “halfstrength” or “bedtime” hs At bedtime, hours of sleep Mistaken as half-strength IU** International unit Mistaken as IV (intravenous) or 10 (ten) Premature Use “discharge” discontinuation of and medications if D/C “discontinue” (intended to mean “discharge”) has been misinterpreted as “discontinued” when followed by a list of discharge medications Use “units” 87 SEC 5 Lists ISMP’s List of Error-Prone Abbreviations, Symbols, and Dose Designations – cont’d ABBREVIATIONS INTENDED MEANING MISINTERPRETATION CORRECTION ABBREVIATIONS INTENDED MEANING MISINTERPRETATION CORRECTION o.d. or OD Once daily Mistaken as “right eye” (OD-oculus dexter), leading to oral liquid medications administered in the eye Use “daily” SC, SQ, sub q Subcutaneous Use “subcut” or “subcutaneously” OJ Orange juice Mistaken as OD or OS (right or left eye); drugs meant to be diluted in orange juice may be given in the eye Use “orange juice” SC mistaken as SL (sublingual); SQ mistaken as “ 5 every;” the “q” in “sub q” has been mistaken as “every” (e.g., a heparin dose ordered “sub q 2 hours before surgery” misunderstood as every 2 hours before surgery) Per os By mouth, orally The “os” can be mistaken as “left eye” (OS-oculus sinister) Use “PO,” “by mouth,” or “orally” ss Sliding scale (insulin) or 1⁄2 (apothecary) Mistaken as “55” q.d. or QD** Every day Mistaken as q.i.d., especially if the period after the “q” or the tail of the “q” is misunderstood as an “i” Use “daily” Spell out “sliding scale;” use “one-half” or “1⁄2” SSRI Sliding scale regular insulin Mistaken as selective-serotonin reuptake inhibitor Spell out “sliding scale (insulin)” SSI qhs Nightly at bedtime Mistaken as “qhr” or every hour Use “nightly” Sliding scale insulin Mistaken as Strong Solution of Iodine (Lugol’s) Nightly or at bedtime Mistaken as “qh” (every hour) Use “nightly” or “at bedtime” i/d One daily Mistaken as “tid” Use “1 daily” TIW or tiw 3 times a week Every other day Mistaken as “q.d.” (daily) or “q.i.d. (four times daily) if the “o” is poorly written Use “every other day” Mistaken as “3 times a day” or "twice in a week" Use “3 times weekly” U or u** Unit Mistaken as the number 0 or 4, causing a 10-fold overdose or greater (e.g., 4U seen as “40” or 4u seen as “44”); mistaken as “cc” so dose given in volume instead of units (e.g., 4u seen as 4cc) Use “unit” UD As directed (“ut dictum”) Mistaken as unit dose (e.g., diltiazem 125 mg IV infusion “UD” misinterpreted as meaning to give the entire infusion as a unit [bolus] dose) Use “as directed” qn q.o.d. or QOD** q1d Daily Mistaken as q.i.d. (four times daily) Use “daily” q6PM, etc. Every evening at 6 PM Mistaken as every 6 hours Use “daily at 6 PM” or “6 PM daily” 88 SEC 5 89 SEC 5 Lists ISMP’s List of Error-Prone Abbreviations, Symbols, and Dose Designations – cont’d DOSE DESIGNATIONS AND OTHER INFO INTENDED MEANING Trailing zero after decimal point (e.g., 1.0 mg)** 1 mg “Naked” decimal point (e.g., .5 mg)** 0.5 mg Abbreviations such as mg. or mL. with a period following the abbreviation mg Drug name and dose run together (especially problematic for drug names that end in “l” such as Inderal40 mg; Tegretol300 mg) Inderal 40 mg Numerical dose and unit of measure run together (e.g., 10mg, 100mL) Large doses without properly placed commas (e.g., 100000 units; 1000000 units) 90 SEC 5 mL Tegretol 300 mg 10 mg 100 mL 100,000 units 1,000,000 units MISINTERPRETATION CORRECTION Mistaken as 10 mg if the decimal point is not seen Do not use trailing zeros for doses expressed in whole numbers Mistaken as 5 mg if the decimal point is not seen Use zero before a decimal point when the dose is less than a whole unit The period is unnecessary and could be mistaken as the number 1 if written poorly Use mg, mL, etc. without a terminal period Mistaken as Inderal 140 mg Place adequate space between the drug name, dose, and unit of measure Mistaken as Tegretol 1300 mg The “m” is sometimes mistaken as a zero or two zeros, risking a 10- to 100-fold overdose Place adequate space between the dose and unit of measure 100000 has been mistaken as 10,000 or 1,000,000; Use commas for dosing units at or above 1,000, or use words such as 100 “thousand” or 1 “million” to improve readability 1000000 has been mistaken as 100,000 DRUG NAME ABBREVIATIONS INTENDED MEANING MISINTERPRETATION CORRECTION To avoid confusion, do not abbreviate drug names when communicating medical information. Examples of drug name abbreviations involved in medication errors include: APAP acetaminophen Not recognized as acetaminophen Use complete drug name ARA A vidarabine Mistaken as cytarabine (ARA C) Use complete drug name AZT zidovudine (Retrovir) Mistaken as azathioprine or aztreonam Use complete drug name CPZ Compazine (prochlorperazine) Mistaken as chlorpromazine Use complete drug name DPT DemerolPhenerganThorazine Mistaken as diphtheriapertussis-tetanus (vaccine) Use complete drug name DTO Diluted tincture of opium, or deodorized tincture of opium (Paregoric) Mistaken as tincture of opium Use complete drug name HCl hydrochloric acid or hydrochloride Mistaken as potassium chloride (The “H” is misinterpreted as “K”) Use complete drug name unless expressed as a salt of a drug HCT hydrocortisone Mistaken as hydrochlorothiazide Use complete drug name HCTZ hydrochlorothiazide Mistaken as hydrocortisone (seen as HCT250 mg) Use complete drug name MgSO4** magnesium sulfate Mistaken as morphine sulfate Use complete drug name MS, MS04** morphine sulfate Mistaken as magnesium sulfate Use complete drug name 91 SEC 5 Lists ISMP’s List of Error-Prone Abbreviations, Symbols, and Dose Designations – cont’d DRUG NAME ABBREVIATIONS INTENDED MEANING MISINTERPRETATION CORRECTION MTX methotrexate Mistaken as mitoxantrone Use complete drug name NoAc novel/new oral anticoagulant No anticoagulant Use complete drug name PCA procainamide Mistaken as patient controlled analgesia Use complete drug name PTU propylthiouracil Mistaken as mercaptopurine Use complete drug name T3 Tylenol with codeine No. 3 Mistaken as liothyronine Use complete drug name TAC triamcinolone Mistaken as tetracaine, Adrenalin, cocaine Use complete drug name TNK TNKase TPA ot tPA tissue plasminogen activator, Activase (atteplase) Mistaken as TNKase (tenecteplase), or less often as another tissue plasminogen activator, Retavase (retaplase) Use complete drug names zinc sulfate Mistaken as morphine sulfate Use complete drug name INTENDED MEANING MISINTERPRETATION CORRECTION “Nitro” drip nitroglycerin infusion Mistaken as sodium nitroprusside infusion Use complete drug name “Norflox” norfloxacin Mistaken as Norflex Use complete drug name “IV Vanc” intravenous vancomycin Mistaken as Invanz Use complete drug name ZnS04 STEMMED DRUG NAMES 92 SEC 5 Mistaken as “TPA” SYMBOLS INTENDED MEANING MISINTERPRETATION CORRECTION Dram Symbol for dram mistaken as “3” Use the metric system Minim Symbol for minim mistaken as “mL” x3d For three days Mistaken as “3 doses” Use “for three days” > and < Greater than and less than Mistaken as opposite of intended; mistakenly use incorrect symbol; “<10” mistaken as “40” Use “greater than” or “less than” / (slash mark) Separates two doses or indicates “per” Mistaken as the number 1 (e.g., “25 units/10 units” misread as “25 units and 110” units) Use “per” rather than a slash mark to separate doses @ At Mistaken as “2” Use “at” & And Mistaken as “2” Use “and” + Plus or and Mistaken as “4” Use “and” ° Hour Mistaken as a zero (e.g., q2° seen as q 20) Use “hr,” “h,” or “hour” zero, null sign Mistaken as numerals 4, 6, 8, and 9 0 or zero, or describe intent using whole words Use complete drug name φ or ∅ **These abbreviations are included on The Joint Commission’s “minimum list” of dangerous abbreviations, acronyms, and symbols that must be included on an organization’s “Do Not Use” list, effective January 1, 2004. Visit www.jointcommission.org for more information about this Joint Commission requirement. ISMP 2015. Permission is granted to reproduce material with proper © attribution for internal use within healthcare organizations. Other reproduction is prohibited without written permission from ISMP. Report actual and potential medication errors to the ISMP National Medication Errors Reporting Program (ISMP MERP) via the Web at www.ismp.org or by calling 1-800-FAIL-SAF(E). www.ismp.org 93 SEC 5 Tables Conversion Tables The approximate dose equivalents used in the following Conversion Tables have been adopted by the United States Pharmacopeia and the National Formulary, and have the approval of the federal Food and Drug Administration. LIQUID MEASURE* SEC 5 METRIC APPROXIMATE APOTHECARY EQUIVALENTS METRIC APPROXIMATE APOTHECARY EQUIVALENTS 30 g 1 ounce 30 mg ½ grain METRIC APPROXIMATE APOTHECARY EQUIVALENTS METRIC APPROXIMATE APOTHECARY EQUIVALENTS 15 g 4 drams 25 mg 3⁄8 grain 10 g 2½ drams 20 mg 1⁄3 grain 1000 mL 1 quart 3 mL 45 minims 7.5 g 2 drams 15 mg ¼grain 750 mL 11⁄2 pints 2 mL 30 minims 6g 90 grains 12 mg ¹⁄₅ grain 500 mL 1 pint 1 mL 15 minims 5g 75 grains 10 mg 1⁄6 grain 250 mL 8 fluid ounces 0.75 mL 12 minims 4g 60 grains (1 dram) 8 mg 1⁄8 grain 200 mL 7 fluid ounces 0.6 mL 10 minims 3g 45 grains 6 mg 1⁄₁₀ grain 8 minims 2g 30 grains (½ dram) 5 mg 1⁄₁₂ grain 100 mL 3½ fluid ounces 0.5 mL 50 mL 1¾ fluid ounces 0.3 mL 5 minims 1.5 g 22 grains 4 mg 1⁄₁₅ grain 30 mL 1 fluid ounce 0.25 mL 4 minims 1g 15 grains 3 mg 1⁄₂₀ grain 15 mL 4 fluid drams 0.2 mL 3 minims 750 mg 12 grains 2 mg 1⁄₃₀ grain 600 mg 10 grains 1.5 mg 1⁄₄₀ grain 500 mg 7½ grains 1.2 mg 1⁄₅₀ grain 400 mg 6 grains 1 mg 1⁄₆₀ grain 10 mL 2½ fluid drams 0.1 mL 1½ minims 8 mL 2 fluid drams 0.06 mL 1 minim 5 mL 1 ¼ fluid drams 0.05 mL ¾ minim 4 mL 1 fluid dram 0.03 mL ½ minim *Metric Doses (With Approximate Apothecary Equivalents) 94 WEIGHT* 300 mg 5 grains 800 µg 1⁄₈₀ grain 250 mg 4 grains 600 µg 1⁄₁₀₀ grain 200 mg 3 grains 500 µg 1⁄₁₂₀ grain 150 mg 2½ grains 400 µg 1⁄₁₅₀ grain 125 mg 2 grains 300 µg 1⁄₂₀₀ grain 100 mg 1 ½ grains 250 µg 1⁄₂₅₀ grain 75 mg 1 ¼ grains 200 µg 1⁄₃₀₀ grain 60 mg 1 grain 150 µg 1⁄₄₀₀ grain 50 mg ¾ grain 120 µg 1⁄₅₀₀ grain 40 mg 2⁄3 grain 100 µg 1⁄₆₀₀ grain *Metric Doses (With Approximate Apothecary Equivalents) 95 SEC 5 Tables Conversion Tables – cont’d Tables WEIGHTS, MEASURES, AND EQUIVALENTS 1 centimeter = 0.3937 inch 1 fluid ounce = 29.57353 milliliters 1 gallon = 4 quarts 1 gallon = 3.7854 liters 1 gram = 1,000 milligrams 1 grain = 64.79891 milligrams 1 inch = 2.54 centimeters 1 kilogram = 2.205 pounds 1 kilogram = 1,000 grams 1 liter = 1,000 milliliters 1 meter = 39.37 inches 1 millimeter = 0.03937 inch 1 ounce, avoirdupois (oz avdp) = 28.35 grams 1 pint = 16 fluid ounces 1 pound, avoirdupois (lb avdp) = 453.60 grams 1 quart = 2 pints 1 tablespoon, measuring = 15 milliliters 1 teaspoon, measuring = 5 milliliters WEIGHTS, MEASURES, AND EQUIVALENTS Fahrenheit degrees to Celcius = Subtract 32, multipy by 5, divide by 9 Celcius degrees to Fahrenheit = Multiply by 9, divide by 5, add 32 96 SEC 5 Assessment Of Liver Function The Child-Turcotte-Pugh Scoring System is used to stratify disease severity, surgical risk, and overall prognosis in patients with cirrhosis. CHILD-TURCOTTE-PUGH SCORING SYSTEM CLINICAL / LABORATORY FACTOR DEGREE OF ABNORMALITY POINTS ASSIGNED Encephalopathya None 1-2 3-4 1 2 3 1 2 Ascites None Mild or controlled on diuretics At least moderate despite diuretic treatment Prothrombin Time (PT), seconds prolonged <4 4-6 >6 __________ 1 2 3 __________ International Normalized Ratio (INR) <1.7 1.7-2.3 >2.3 1 2 3 Albumin (g/dL) >3.5 2.8-3.5 <2.8 1 2 3 Bilirubin (mg/dL) <2 2-3 >3 1 2 3 OR 3 a Encephalopathy is graded based on symptoms: 1: Sleep disturbances; impaired concentration; depression, anxiety, or irritability 2: Drowsiness, disorientation, poor short-term memory, uninhibited behavior 3: S omnolence; confusions; amnesia; anger, paranoia, or other bizarre behavior 4: Coma Child-Turcotte-Pugh Risk (grade) based on the total number of points. • Low (A): 5-6 points • Moderate (B): 7-9 points • High (C): 10-15 points 97 SEC 5 Tables Assessment Of Liver Function – cont’d Formulas INTERPRETATION OF THE CHILD-TURCOTTE-PUGH SCORING SYSTEM NUMBER OF TOTAL POINTS CHILD-TURCOTTE-PUGH RISK (GRADE) 2-YEAR SURVIVAL RATE (%) 5-6 Low (A) 85 7-9 Moderate (B) 60 10-15 High (C) 35 CREATININE CLEARANCE FORMULA Measuring creatinine clearance using serum concentration level and timed urine collection provides an estimate of glomerular filtration rate (GFR): Creatinine Clearance (ClCr) =(urine creatinine x volume) ___________________________ serum creatinine COCKCROFT-GAULT EQUATION The estimated creatinine clearance rate using Cockcroft-Gault equation is as follows: ClCr(est) (mL/min) = [140 – age (yrs)] x weight (kilograms) x 0.85 if female __________________________________ 72 x serum creatinine (mg/dL) MODIFICATION OF DIET ON RENAL DISEASE (MDRD) STUDY EQUATION The original MDRD Study Equation – suitable for use with creatinine methods that DO NOT have calibration traceable to isotope dilution mass spectrometry (IDMS): GFR(est) (mL/min per 1.73 m2) = 186 x [serum creatinine (mg/dL)]-1.154 x [age (yrs)]-0.203 x (0.742 if female) x (1.212 if African American) The MDRD Study Equation – re-expressed for use with standardized serum creatinine levels: GFR(est) (mL/min per 1.73 m2) = 175 x [standardized serum creatinine (mg/dL)]-1.154 x [age (yrs)]-0.203 x (0.742 if female) x (1.212 if African American) 98 SEC 5 99 SEC 5 Formulas Formulas For Body Surface Area Codes Codes For Therapeutic Equivalence Evaluations “A” codes are used for drug products considered to be therapeutically equivalent to other pharmaceutically equivalent products. THE MOSTELLER FORMULA BSA (m2) = ([Height (cm) x Weight (kg)]/3600)(½) "A" CODES THE DUBOIS AND DUBOIS FORMULA BSA (m ) = 0.007184 x Height (cm) 2 0.725 x Weight (kg) THE HAYCOCK FORMULA BSA (m2) = 0.024265 x Height (cm) 0.3964 x Weight (kg) 0.5378 THE GEHAN AND GEORGE FORMULA BSA (m ) = 0.02350 x Height (cm) 2 0.42246 x Weight (kg) FORMULAS FOR LEAN BODY WEIGHT Lean Body Weight (men) = (1.10 x weight (kg)) - 128 (weight2/height (cm)2) Lean Body Weight (women) = (1.07 x weight (kg)) - 148 (weight 2/height (cm) 2) AA roducts in conventional dosage forms not presenting P bioequivalence problems AB Products meeting necessary bioequivalence requirements [AB1, AB2, AB3…] AN Solutions and powders for aerosolization AO Injectable oil solutions AP Injectable aqueous solutions and, in certain instances, intravenous non-aqueous solutions Topical products 0.425 AT 0.51456 "B” codes are used for drug products that FDA, at this time, considers not to be therapeutically equivalent to other pharmaceutically equivalent products. "B" CODES B* rug products requiring further FDA investigation and review D to determine therapeutic equivalence BC Extended-release dosage forms (capsules, injectables and tablets) BD ctive ingredients and dosage forms with documented A bioequivalence problems BODY MASS INDEX (BMI) FORMULA BMI = Weight (kg) / Height (meters)2 100 SEC 5 BE Delayed-release oral dosage forms BN Products in aerosol-nebulizer drug delivery systems BP Active ingredients and dosage forms with potential bioequivalence problems BR Suppositories or enemas that deliver drugs for systemic absorption BS Products having drug standard deficiencies BT Topical products with bioequivalence issues BX rug products for which the data are insufficient to D determine therapeutic equivalence 101 SEC 5 Alert High-Alert Medications INSTITUTE FOR SAFE MEDICATION PRACTICES (ISMP) LIST OF HIGH-ALERT MEDICATIONS IN ACUTE SETTINGS High-alert medications are drugs that bear a heightened risk of causing significant patient harm when they are used in error. Although mistakes may or may not be more common with these drugs, the consequences of an error are clearly more devastating to patients. We hope you will use this list to determine which medications require special safeguards to reduce the risk of errors. This may include strategies like improving access to information about these drugs; limiting access to high-alert medications; using auxiliary labels and automated alerts; standardizing the ordering, storage, preparation, and administration of these products; and employing redundancies such as automated or independent double-checks when necessary. (Note: manual independent double-checks are not always the optimal error-reduction strategy and may not be practical for all of the medications on the list). CLASSES/CATEGORIES OF MEDICATIONS adrenergic agonists, IV (e.g., EPINEPHrine, phenylephrine, norepinephrine) adrenergic antagonists, IV (e.g., propranolol, metoprolol, labetalol) anesthetic agents, general, inhaled and IV (e.g., propofol, ketamine) dialysis solutions, peritoneal and hemodialysis epidural or intrathecal medications hypoglycemics, oral inotropic medications, IV (e.g., digoxin, milrinone) insulin, subcutaneous and IV liposomal forms of drugs (e.g., liposomal amphotericin B) and conventional counterparts (e.g., amphotericin B desoxycholate) moderate sedation agents, IV (e.g., dexmedetomidine, midazolam) moderate sedation agents, oral, for children (e.g., chloral hydrate) narcotics/opioids • IV • transdermal • oral (including liquid concentrates, immediate and sustained-release formulations) neuromuscular blocking agents (e.g., succinylcholine, rocuronium, vecuronium) parenteral nutrition preparations radiocontrast agents, IV sterile water for injection, inhalation, and irrigation (excluding pour bottles) in containers of 100 mL or more sodium chloride for injection, hypertonic, greater than 0.9% concentration antiarrhythmics, IV (e.g., lidocaine, amiodarone) antithrombotic agents, including: • anticoagulants (e.g., warfarin, low molecular weight heparin, IV unfractionated heparin) • Factor Xa inhibitors (e.g., fondaparinux) • direct thrombin inhibitors (e.g., argatroban, bivalirudin, dabigatran etexilate, lepirudin) • thrombolytics (e.g., alteplase, reteplase, tenecteplase) • glycoprotein IIb/IIIa inhibitors (e.g., eptifibatide) cardioplegic solutions chemotherapeutic agents, parenteral and oral dextrose, hypertonic, 20% or greater 102 SEC 5 103 SEC 5 Alert High-Alert Medications – cont'd SPECIFIC MEDICATIONS EPINEPHrine, subcutaneous epoprostenol (Flolan), IV insulin U-500 (special emphasis)* magnesium sulfate injection methotrexate, oral, nononcologic use opium tincture oxytocin, IV nitroprusside sodium for injection potassium chloride for injection concentrate BACKGROUND Based on error reports submitted to the ISMP National Medication Errors Reporting Program, reports of harmful errors in the literature, studies that identify the drugs most often involved in harmful errors, and input from practitioners and safety experts, ISMP created and periodically updates a list of potential highalert medications. During May and June 2014, practitioners responded to an ISMP survey designed to identify which medications were most frequently considered highalert drugs by individuals and organizations. Further, to assure relevance and completeness, the clinical staff at ISMP, members of the ISMP advisory board, and safety experts throughout the US were asked to review the potential list. This list of drugs and drug categories reflects the collective thinking of all who provided input. potassium phosphates injection promethazine, IV vasopressin, IV or intraosseous *All forms of insulin, subcutaneous and IV, are considered a class of high-alert medications. Insulin U500 has been singled out for special emphasis to bring attention to the need for distinct strategies to prevent the types of errors that occur with this concentrated form of insulin. © ISMP 2014. Permission is granted to reproduce material with proper attribution for internal use within healthcare organizations. Other reproduction is prohibited without written permission from ISMP. Report actual and potential medication errors to the ISMP National Medication Errors Reporting Program (ISMP MERP) via the website (www. ismp.org) or by calling 1 800-FAIL-SAF(E). A reference list for this Clinical Resources section can be requested from Dr. Reddy’s Laboratories, Inc. 104 SEC 5 105 SEC 5 At Dr. Reddy’s We’re Proud To Be Doing Our Part More than 85% of U.S. prescriptions are filled with generic drugs, saving Americans more than $200 billion in healthcare costs annually. SOURCE: 2014 GPhA As one of the top ten generic pharmaceutical providers in the United States*, we’ve made it our business to make medicines more affordable for millions of Americans. It’s something we take very seriously. Over the next few years, we commit to investing 11% of our revenue directly into R&D as we look to continue to build our pipeline of innovative, and sometimes lifesaving, medicines — addressing the urgency and need for more affordable, high quality pharmaceuticals now and into the future. * Based on September 2015 IMS Sales MAT. Source: IMS Health, National Prescription Audit, September 2015. Dr. Reddy’s Laboratories, Inc. 107 College Road East Princeton, NJ 08540 Tel: 866-733-3952 www.drreddys.com ©2015 Dr. Reddy’s Laboratories, Inc. RDY-0215-096 All right reserved. December 2015 To order additional copies of this guide, please contact our customer service department at: 1-866-733-3952. Dr. Reddy’s Laboratories, Inc. 10 College Road East Princeton, NJ 08540 Tel: 866-733-3952 www.drreddys.com ©2016 Dr. Reddy’s Laboratories, Inc. All rights reserved. RDY-1115-122 January 2016
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