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UNLOCK YOUR INNER POWER TO GROH® The Ergo Boost products work internally with the body’s complex biological system to fulfill everyday nutritional needs that diet alone fail to provide, supporting healthy hair, scalp, skin, nails, and lashes. GROH® Created by Nature. Unlocked by Science. © Total Nutraceutical Solutions, Inc. 2014 GROH® Ergo Boost Discovery & Innovation INDUSTRY LEADER Entia Biosciences, an innovator in the Life Sciences industry, is leading the way in identifying new therapies through the science of Nutrigenomics. Under the direction of Dr. Marvin S. Hausman MD and an esteemed team of scientists spanning multiple disciplines, Entia seeks to unlock the answers to our body’s genetic requirement for nutrients, many of which Entia believes are disappearing from our diet as a result of modern farming and agricultural practices. entia BIOSCIENCES GROH’s UNEXPECTED DISCOVERY While Dr. Hausman and his team may never have intended to enter the world of beauty, several observations were made during pre-clinical studies designed to examine the benefits of an enhanced mushroombased medical food concentrated with Ergothioneine & Vitamin D2. Initially, many of the study participants reported improvements in their hair and nails, both good indicators of overall wellness. However, it was the discovery of the Ergothioneine Transporter within the hair follicle and in key skin cells GROH® Created by Nature. Unlocked by Science. that made it very clear: Entia’s technology could dynamically revolutionize the way we approach beauty through wellness. It is this technology and innovation that serves as the foundation of GROH’s Ergo Boost Line of products. ALL NATURAL SOURCE Why mushrooms? Mushrooms (fungi) play a key role within our ecosystem. They naturally fortify plants by releasing nutrients into the soil. Changes in modern agricultural processes over the last century (including: heavy tilling, pesticides, herbicides, etc...) have caused a disturbance in this process and may explain the decreasing concentration in Ergothioneine and other nutrient levels in our population. GROH® is formulated using a select group of medicinal mushrooms that are enhanced and concentrated with Ergothioneine and Ergocalciferol (Vitamin D2), utilizing a patented UV-enrichment process. In order to assure the highest level of quality ingredients and bio-availability, this process is performed in the USA at Entia’s own FDA-registered and USDA-Certified Organic facility. entia BIOSCIENCES Discovery that Ergothioneine levels have decreased over the last 80 years • Salt HB. (1931) The Ergothioneine Content of the Blood in Health and Disease. Biochem 25(34): 1712-1719 • Weigand-Heller AJ, Kris-Etherton PM, Beelman RB. (2012) The bioavailability of ergothioneine from mushrooms (Agaricus bisporus) and the acute effects on antioxidant capacity and biomarkers of inflammation. Prev Med. 54 Suppl:S75-8. Mushroom and Fungi - Function in the Ecosystem (Nutrient Difficancy) • Miller R.M, Lodge D.J. (1997) 5 Fungal responses to disturbance: agriculture and forestry. Environmental and Microbial Relationships 65-84. • Matson P.A, Parton W.J, Power A.G, Swift M.J. (1997) Agricultural intensification and ecosystem properties. Science 277, 504. • Trappe J, Luoma D. The Ties that Bind: Fungi in Ecosystems. Oregon State University 17-20. Ergothioneine - Prodcued by Mushrooms • Beelman R. Ergothioneine in Mushrooms-Nature’s Best Source of a New Human Vitamin. Penn State University. Presentation Ergothioneine - Genetic Transporter Identified in Hair Bulb using IHC Study • Hausman, Burmer, (2011) Entia Biosciences Ergothioneine IHC Data Summary © Total Nutraceutical Solutions, Inc. 2014 SCIENCE & DISCOVERY Smart Nutrients Ergothioneine & Vitamin D POWERFUL SCIENCE The foundation of GROH® products and services is our revolutionary antiaging approach: using the science of Nutrigenomics to boost the body’s own repair systems and encourage healthy and youthful cellular function throughout the body. GROH® products are made with naturally enriched nutrients derived from mushrooms: Ergothioneine and vitamin D2. These two essential nutrients are required by the body but are often in insufficient supply in our modern-day diets. Ergothioneine Vitamin D2 DEDICATED DELIVERY SYSTEM While other ‘targeted delivery’ beauty products use liposome-based packaging to trick the cell into absorbing the packaged nutrients, GROH® products use a genetically encoded delivery system to ensure that nutrients are absorbed by the cells that need them most. For example, Ergothioneine is delivered via a dedicated transporter, which is present in high levels in the hair bulb, skin, nail bed, and many other tissues in the body. Levels of Ergothioneine Transporter increase when cells are subjected to inflammation or oxidative stress, as occurs in alopecia, various skin conditions such as eczema or psoriasis, as well as in chronic auto-immune, metabolic, GROH® Created by Nature. Unlocked by Science. and neurodegenerative diseases. These increases in Transporter levels suggest that cells under stress need Ergothioneine to restore their function. CELLULAR FUNCTIONS Once inside the cell, Ergothioneine functions as a potent antioxidant, works to reduce inflammation, and boosts various cellular processes. The effects of Ergothioneine in the cell are complemented by vitamin D, which is important for cellular growth and immune function. Because GROH® products promote healthy cellular function and have the ability to target stressed cells, users can experience dramatic improvements in hair, skin, and nail health. “The discovery of the Ergothioneine Transporter and its direct expression within hair and skin cells will transform the fundamental way we approach beauty and wellness.” - Marvin S. Hausman M.D. Hair bulb Expressing the Ergothioneine Transporter (gene symbol SLC22A4) PATENTED GENETIC TRANSPORT TECHNOLOGY entia BIOSCIENCES Smart Nutirent Delivery System (Hair & Skin) • Grundemann D. (2011) The ergothioneine transporter controls and indicates ergothioneine activity-A review. University of Cologne. 54(2012):S71-S74. • Grundemann D, Harlfinger S, Golz S, Geerts A, Lazar A, Berkels R, Jung N, Rubber A, Schomig E (2005) Discovery of the ergothioneine Transporter. Proceedings of the National Academy of Sciences 102 (14): 5256-5261 • Perederiy JV, Hausman M. (2013) Impact of GROH Hair & Scalp Conditioning Treatment and Daily Replenishing Supplement on Hair Growth and Wellness. Entia Biosciences 2013. Cellular Protection, & Regeneration • Paul BD, Snyder SH. (2009) The unusual amino acid L-ergothioneine is a physiologic cytoprotectant. Cell Death and Differentiation. 1(1), 1-7. • Aruoma OJ, Spencer JP, Mahmood N. (1999) Protection against oxidative damage and cell death by the natural antioxidant ergothioneine. Food Chem Toxicol 37:1043–1053. • Hartman, PE. (1990) Ergothioneine as antioxidant. Methods Enzymol. 186:310–318. • Obayashi K, Kurihara K, Okano Y, Masaki H, Yarosh DB. (2005) L-Ergothioneine scavenges superoxide and singlet oxygen and suppresses TNF-alpha and MMP-1 expression in UV-irradiated human dermal fibroblasts. J Cosmet Sci. 56(1):17-27. • Rahman I, Gilmour PS, Jimenez LA, Biswas SK, Antonicelli F, Aruoma OI. (2003) Ergothioneine inhibits oxidative stress- and TNF-alpha-induced NF-kappa B activation and interleukin-8 release in alveolar epithelial cells. Biochem Biophys Res Commun. 302(4):860-4. GROH® Ergo Boost The Lifestyle Kit ADVANCED BOOSTING TECHNOLOGY Exceed your guests expectations with natural effective formulations. GROH’s Advanced Boosting Technology Offers targeted delivery of key nutrients for the support of healthy hair, scalp, skin, nails, and lashes. LIFESTYLE LINE & PRO SERVICES • • • • • Balances cellular structures Improves skin condition Increases nail strength & growth Encourages healthier hair & lashes Promotes thicker, fuller hair • Revitalizes damaged hair GROH® Created by Nature. Unlocked by Science. © Total Nutraceutical Solutions, Inc. 2014 Thicker, Fuller Hair Advanced Hair & Scalp Treatment Targeted to your individual hair needs Ergo Boost Hair & Scalp Conditioning Treatment Daily hair and scalp conditioning treatment. Hydrating and smoothing formulation of pure essential oils – coconut oil, argan oil (infused with vitamin D), rosemary, lemon peel, lavender, and sweet almond oil – work together to replenish hair and nourish scalp. R Use: Massage into towel dried hair and scalp. Allow 2-3 minutes for absorption. Rinse. For best results use 2 times per week or every time you wash your hair. Results: This hydrating and smoothing formulation replenishes hair and nourishes scalp. Targeted delivery of essential nutrients activates cellular regeneration to encourage hair growth and repair for thicker, shinier, healthier-looking hair S DER CHOI EA CE Hair types: All hair types launchpad AWARD WINNER VOTED BEST THINNING REGIMEN GROH® received Beauty Launchpad magazine’s Readers’ Choice awards in both women’s and men’s haircare categories. The GROH® Ergo Boost Hair and Scalp Conditioning Treatment is an all-natural product recognized as “Best Women’s Thinning Regimen” and “Best Men’s Thinning Treatment” winner. GROH® Created by Nature. Unlocked by Science. © Total Nutraceutical Solutions, Inc. 2014 Targeted Nutrients Advanced Nutritional Supplement Targeted to your individual cellular needs Ergo Boost Daily Replenishing Supplement A whole food, all-natural dietary supplement, containing a blend of six ultra-potent mushrooms promotes detoxification, reduces inflammation, boosts energy and offers nutritional support for cellular health of skin, hair, scalp, nails, and lashes. Use: Morning or early afternoon. As a dietary supplement, take 2-4 capsules daily. Nail Results: Strengthens and fortifies nails, stimulates growth. Skin Results: Radiant, hydrated, and younger looking skin. Hair Results: Smoother and increased shine. Strengthens and stimulates growth. Wellbeing Results: Reduces inflammation, strengthens immune system, boosts energy. GROH® Created by Nature. Unlocked by Science. © Total Nutraceutical Solutions, Inc. 2014 Detoxifying Cleanse Advanced Vitamin & Antioxidant Bar Detoxifying and nourishing Ergo Boost Skin Recharge Cleansing Bar Gentle and nourishing cleansing bar for all skin types infused with a rich blend of pure essential oils and antioxidants. Skin types: All skin types Use: Morning and evening. Activate with a splash of warm water to create a lush lather. Gently massage into face, neck, and décolleté. Rinse thoroughly. Results: Soothes the skin, improves tone and texture, nourishes and protects, revealing healthy, smooth, glowing skin. GROH® Created by Nature. Unlocked by Science. © Total Nutraceutical Solutions, Inc. 2014 Targeted Skin Care Advanced Serum and Moisturizer Targeted to your individual skin needs Ergo Boost Skin Repair Treatment A gentle and moisturizing skin treatment for all types of skin. Fast-absorbing, rich in antioxidants and vitamin D2. Essential age-fighting nutrients work at a cellular level to repair and stimulate collagen production. Skin types: All skin types Use: Morning and evening. Gently apply to face, neck, décolleté, and cuticles. Skin Results: Inhibits the oxidation process and limits the spread of free radicals. More radiant, resilient, younger looking skin. Results on cuticle: When applied to nail bed and hands, this solution hydrates, soothes and minimizes inflammation. GROH® Created by Nature. Unlocked by Science. © Total Nutraceutical Solutions, Inc. 2014 GROH® ERGO BOOST Lifestyle Kit For healthy hair, skin and nails GROH® Ergo Boost™ An all-natural lifestyle line of skin and hair care products created specifically for the professional salon & spa industry. Ergo Boost™ Hair & Scalp Conditioning Treatment Hydrating and smoothing formulation replenishes hair and nourishes scalp. A rich blend of pure essential oils – argan oil infused with organic vitamin D2, coconut, rosemary, lemon peel, lavender, and sweet almond oil – work together to hydrate and smooth, while the antioxidant-rich Ergo Boost Complex delivers potent micronutrients to both hair and scalp to recharge and protect them from daily stresses and future damage. Ergo Boost™ Daily Replenishing Supplement Ultra-potent, all-natural supplement offers nutritional support for cellular health for stronger skin, hair, scalp, nails, and lashes. Rich in antioxidants and bionutrients, this formula replenishes the body’s essential building blocks and supports a healthy immune system. GROH® Created by Nature. Unlocked by Science. Skin Repair Treatment A gentle and moisturizing skin treatment for all types of skin. Fast-absorbing Ergo Boost Complex, rich in antioxidants and vitamin D2, inhibits the oxidation process and limits the spread of free radicals. Essential age-fighting nutrients work at a cellular level to repair and stimulate collagen production for radiant, resilient, younger- looking skin. Ergo Boost™ Skin Recharge Cleansing Bar Gentle and nourishing skin recharge bar infused with a rich blend of pure essential oils and antioxidants. Gently cleanses away impurities and recharges the skin with fast-absorbing Ergo Boost bionutrients that nourish and protect to reveal healthy, smooth, glowing skin. Luxurious In-Salon Service Advanced Hair & Scalp Treatment Ultra-Potent, targeted to your individual hair & scalp needs Ergo Boost Professional Hair & Scalp Treatment A luxurious, deep-conditioning, in-salon treatment provides ultra hydration, smoothing and anti-aging benefits. Infused with a concentrated dosage of Ergo Boost Complex, this professional hair and scalp treatment rapidly absorbs, delivering essential nutrients and activating cellular regeneration to encourage hair growth and repair for thicker, shinier, healthier-looking hair. How to Deliver: This intensive treatment begins at the shampoo bowl after freshly shampooing and towel drying hair. Apply the entire tube of the Ergo Boost™ Treatment to scalp. Massage in for 3-5 minutes to stimulate blood flow and absorption. Pull through ends of hair. Rinse with warm water. Style as usual. To enhance the treatment (before rinsing) put a processing cap on the guest and place under a warm dryer for 7-10 minutes to open the cuticle and maximize nutrient absorption. $25 ProTreatment Differentiation: - 5x more potent - Plus Chia Seed Oil - Individual Dose GROH® Created by Nature. Unlocked by Science. © Total Nutraceutical Solutions, Inc. 2014 Professional Training & Certification BECOME A GROH CERTIFIED PROFESSIONAL Thank you for partnering with GROH. Please enjoy a complimentary 12 Month Passport to access the GROH Professional Training and Certification Portal. At GROH we recognize that Professional Training drives success and we are excited to invite your salon to attend the GROH on-line training & certification portal. Through this portal your salon will be educated on the benefits of GROH’s boosting technology and instructed how to boost your guest‘s experience with GROH’s luxury line of Ergo Boost Products. Bonus Product FREE LIFESTYLE TRAVEL KIT - $80.00 VALUE GROH® How to Get Certified: Step 1: Register your salon by visiting: http://www.mygroh.com/register-salon and completing the on-line registration form. Step 2: Once the salon registration information has been reviewed by the GROH Salon Support Team, you will receive a “Welcome Email” containing a Salon Registration Key Code and certification instructions. If you do not receive a welcome email within 24 Hours please contact our GROH Salon Support Team by calling 1(866) 998-7173. Each staff member who successfully completes the training will receive a complimentary travel size set of the luxurious lifestyle kit. Hurry! This is a limited time offer and only available while supplies last! Created by Nature. Unlocked by Science. © Total Nutraceutical Solutions, Inc. 2014 CASE STUDY: ANNASTASIA SALON Professional Salon ANNASTASIA STATS Number of Stylists: 23 In business since: 1985 Portland, Oregon - Annastasia's is a full service salon dedicated to helping each guest make a great first and a long lasting impression. Professional Stylists help make guests feel and look their best by crafting a look that uniquely fits each guest's key features. Taking into account their face, skin, and eyes, while accommodating their ideal lifestyle. The staff lives the mission to inspire, educate, and support their guests and one another. While reinforcing that real beauty begins on the inside. Annastasia’s is dedicated to creating an exceptional environment for the salon team to ensure an exceptional experience for each guest. http://www.annastasias.com COMPARATIVE SALES Total Sales OCT13-JAN14 Brand Qty Total Alterna (26) $492 Framesi (464) $9835 Redken (1004) $14,400 Pureology (159) $3,041 GROH® (207) $8,517 REVENUE GROWTH 2013-2014 $2429 $1633 Luke Huffsutter| Salon Owner Has developed a supportive and education oriented salon. This creates an environment where stylists are open to trying new processes and products to create greater success for themselves. This collaborative style of working supports practices that have built a thriving business. LEADERSHIP & GROH® AMBASSADORS Sandie Griffith, Stylist 17 years GROH Brand Ambassador A combination of creative thinking and business sense. The first messenger for a new brand or product, champions innovation and methods in the salon. Works internally training a team to educate and communicate the value GROH products bring. Kristi, April, Toni, & Natalie, Stylists | Early Adopters Smart, active and value driven. Early adopter stylists embrace new innovation and new opportunities. They take initiative to be educated and to share what they are experiencing. They understand that as their business grows that redefines and adds value to their salon guest experience. With a new product and service in their toolbox they can actively engage in a dialog with guests about how GROH contributes to boosting their everyday efforts to live a healthy lifestyle. PRO-TREATMENT CONVERSION RATE Conversions 1/14/14-2/22/14 # of Service Treatments: 52 Customer Conversion Rate: 30% 17 of 52 customers purchased product Conversion Rate 30% $2671 $1784 OCT NOV DEC JAN GROH® Created by Nature. Unlocked by Science. THE HEALING POWER OF NATURE All Natural | Certified Organic Ingredients No Chemicals or Dyes | No Chemical Extracts 100% Vegan | Whole Food | Manufactured in USA © Total Nutraceutical Solutions, Inc. 2014