Spring 2008 - Institute for Complex Engineered Systems
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Spring 2008 - Institute for Complex Engineered Systems
ICES — The Institute for Complex Engineered Systems Carnegie Mellon University Spring 2008 Newsletter www.ices.cmu.edu vascular biomechanics and biofluids laboratory pages 1—2 Image: Vitrea® W/L: 325/270 Segmented ICES, Carnegie Mellon University 1201 Hamburg Hall 5000 Forbes Avenue Pittsburgh, PA 15213-3890 Recipient Name Recipient Title Address Line One Address Line Two iNews • Spring 2008 Newsletter Letter from the Director message from the director Welcome to the Spring ‘08 iNEWS edition! This bi-annual newsletter communicates news, announcements and other useful information to our ICES community. Inside you will find updates on awards and events, highlights from several ongoing research initiatives, and the latest news about the Philip and Marsha Dowd-ICES Fellows. Application details for the 2008 Dowd-ICES Fellowships are located on the ICES website with the due date of May 2. This year, we are proud that ICES swept the CIT Staff Awards! All three winners were from ICES including Christina Cowan, for the Staff Recognition Award, Alicia Brown for the Timothy J. Burritt Education Award and Matt San- The FY2008 project selections for the Pennsylvania Infra- filippo for the Rookie Award. If you didn’t make it to the structure Technology Alliance (PITA) were recently final- awards ceremony, you can read about the details inside ized. Funds were available to support 33 of the 66 project this issue. I am also excited to announce that Rebecca proposals received. In this year’s selection process, direct Gray has joined the ICES staff as Business Coordinator, interactions with Pennsylvania industry partners were joining Rhonda Moyer and Yvonne Brewster in the busi- emphasized even more than in the past. Our colleagues ness office. The addition of Rebecca allows us to begin at Lehigh University, along with Matt Sanfilippo and I, are looking at enhancing our administrative services. When now actively working to ensure continued funding of this you are in the neighborhood of Hamburg Hall, please stop important program for next year. by to welcome her. And last but certainly not least, the ICES faculty and staff Lee Weiss was recently named the recipient of the are in the midst of planning for our President’s Advisory 2007– 2008 Steven J. Fenves Award given for a significant Board meeting in May. As always, I am interested in hear- contribution to systems research in areas relevant to ICES. ing your ideas and comments on ICES, present and future. Lee has been a contributor to systems research extending far before the existence of ICES and its predecessor, the Please enjoy this edition of iNEWS and keep sending in NSF Engineering Design Research Center, and is greatly your stories, comments and feedback! deserving of this award. As of February ‘08, ICES is home to a new Center for Multiscale Modeling of Engineered Materials, CM2EM, with Amit Acharya of Civil and Environmental Engineering as Director and Michael Widom of Physics as Associate Director. CM2EM brings together faculty members from across the entire campus in a unique mission to bridge materials Gary K. Fedder modeling between the atomic, nano-, micro-, meso- and ICES Director macro- scales that will enable revolutionary capabilities to predict behavior of engineered materials. The interdisciplinary nature of the center and its participants makes it a perfect fit within ICES. ICES — The Institute for Complex Engineered Systems Table of Contents in this issue … Biomechanics Research Laboratory Addresses 1 Blood Flow And Its Relationship With Disease Brain Computer Interface Research For 3 Impaired Motor Functioning Dr. Lee Weiss Is The 2007– 2008 Recipient 4 Of The Steven J. Fenves Award ICES Introduces New Interdisciplinary 5 Engineering Center On Multiscale Modeling Honors & Awards 6 ICES Researchers’s NIH-Funded eWatch Study 7 Receives Media Coverage Burcu Akinci’s Research On Construction Proj- 7 ect Control Is Featured Dowd Fellowship News 8 SURE Thing Student’s Research To Be Repre- sented At The IEEE International Conference 8 PITA Collaboration Develops Enterprise-Wide 9 The strength of a “bone” being tested at this year’s National Optimization For Industry Competitiveness Article Examines Combining Profitability And “Outreach Update,” page 11. 10 Environmentally Friendly Electricity Production Student Receives YAHOO! Grant For PITA 10 Blog Research ICES Outreach Receives Media Attention 11 During National Engineers Week Upcoming ICES Events Engineers Week at the Carnegie Science Center. From 12 1 iNews • Spring 2008 Newsletter Biomechanics Feature biomechanics research laboratory addresses blood flow and its relationship with disease regard, the lab’s work includes finding ways to quantify the relationships between vascular biology, structure and biomechanical forces, as well as to design simulation tools based on medical imaging techniques in order to quantify the interactions between medical devices and the vessel wall. The ultimate goal of this research is to optimize the treatment options of vascular diseases and design better medical devices for these options. Vascular diseases and their effects, including carotid artery disease, stroke, and abdominal aortic aneurysms (see Two areas of VBBL research that have yielded funding and Figure 1), affect millions of Americans. In recent decades, press are the lab’s work on (1) understanding the blood flow the role of blood flow and its relationship with disease has and vessel structure relationship in native abdominal aortic created a common focus for both prevention and clinical aneurysms and (2) medical devices to complement carotid management of vascular diseases. During the past two artery stenting for the prevention of stroke. decades, biofluid mechanics has been recognized more widely by researchers in medicine and biology as a key Abdominal Aortic Aneurysm Research factor in the cause of arterial disease and the regulation Receives NIH Funding of haemostasis - stopping the flow of blood - in normal and Dr. Finol was recently awarded $385,812 in NIH funding diseased blood vessels. The ability to model biological flow for VBBL’s work on predicting the rupture potential systems experimentally and numerically is now an important of abdominal aortic aneurysms. The grant, entitled component to fundamental research of vascular disease. “Bioengineering Studies of Abdominal Aortic Aneurysm Fluid and Wall Dynamics,” will support a prospective clinical research study with the objective of investigating the central hypothesis that, once an aneurysm is diagnosed, the primary biomechanical determinant of rupture potential is the non-uniform arterial wall thickness, within the context of a dynamic assessment of aneurysm mechanics. Seed funding provided by the Pennsylvania Infrastructure Technology Alliance (PITA), a grant from the Commonwealth of Pennsylvania Department of Health, and a Dowd-ICES Figure 1. Schematic of carotid artery occlusive disease (left frame) and visualization of a multi-slice thoracic and abdominal computed tomography revealing the presence of an abdominal aortic aneurysm (right frame). Graduate Fellowship provided for the initial stages of this project. During this initial phase, a retrospective review of existing patient records was conducted to determine the feasibility of non-invasively evaluating aneurysmal wall thickness from medical images. The NIH funded research Housed in ICES, the Vascular Biomechanics and Biofluids will be done in collaboration with Prof. James Antaki of Laboratory (VBBL) under the direction of ICES Research the Biomedical Engineerign Department and Drs. Satish Faculty Ender Finol has been conducting just such C. Muluk and Robert W. Biederman at Allegheny General research. The current research projects at VBBL deal Hospital. Dr. Finol, Dr. Muluk and Christine Scotti, a former with: (1) computational biomechanics and (2) design and graduate student in biomedical engineering and ICES and optimization of medical devices. The research vision who has recently published articles on aneurysm numerical of VBBL is based on the development of image-based modeling (see Figure 2) in the journals Computers and computational modeling tools that can be readily utilized Structures and Computer Methods in Biomechanics and in a clinical setting to analyze and plan surgical and Biomedical Engineering. endovascular interventions in a timely manner. In this ICES — The Institute for Complex Engineered Systems Biomechanics Feature Figure 2. Outcome of fluid-structure interaction modeling on two patient-specific aortic aneurysms detailing flow patterns and wall stress distributions. Close to 2 million people in the United States suffer from abdominal aortic aneurysms, defined as a 50% increase in the diameter of a segment of the aorta. The inability to fully assess the status of a patient’s abdominal aortic aneurysm has led to extensive research into other potential indicators of rupture or evaluative criteria for determining surgical repair. The research group at VBBL has developed an application for segmenting threedimensional computed tomography images of the aorta Graduate student Gail Siewiorek injects particle solution based on algorithms that identify and distinguish between into a carotid bifurcation silicone model. the interior of the artery and the outer wall surface in order to assess the aortic wall thickness. (see Figure 3), and they have developed computational and experimental methodologies to support such evaluation. Optimization of Medical Devices for Carotid Artery Stenting Seed funding by the Pennsylvania Infrastructure Technology Carotid artery disease involves the narrowing or blockage Alliance (PITA) and a small grant from the Samuel and of this artery due to plaque build-up. Over time, this Emma Winters Foundation provided for the preliminary narrowing can become severe enough that a blockage studies in this project. This research is being conducted in will decrease blood flow to the brain and may cause a collaboration with Dr. Mark H. Wholey, MD at the University stroke. Carotid artery occlusive disease accounts for of Pittsburgh Medical Center. Dr. Finol, Dr. Wholey and Gail 20-30% of all ischemic strokes. Carotid artery stenting is Siewiorek, graduate student in biomedical engineering a relatively new alternative treatment for severe carotid and ICES, recently published articles on the assessment artery disease. However, it has not yet become widely of distal protection devices in the Journal of Endovascular accepted because there is still some concern about the Therapy and Endovascular Today. Ms. Siewiorek is risk of complications during the stenting procedure due to currently supported by an NIH pre-doctoral training grant distal embolization, which is due to a blockage that may on biomechanics in regenerative medicine, a collaborative occur in cerebral arteries. The research being conducted effort of Carnegie Mellon and University of Pittsburgh. on distal protection devices by VBBL is working to make Future funding for this research is currently sought with the carotid artery stenting a more successful and acceptable goal of developing a model for the prediction of strokes alternative treatment for stroke prevention among and adverse peri-procedural outcomes during carotid endovascular procedures. artery stenting on an individual basis. To address the risk of distal embolization in carotid For more information on research being conducted by artery stenting, VBBL researchers are evaluating the the Vascular Biomechanics and Biofluids Laboratory, carotid artery flow dynamics in the presence of cerebral please contact Ender Finol at finole @ cmu.edu. For more protection with the primary goal of improving the design information on the Vascular Biomechanics and Biofluids of embolic protection filters (EPFs). The lab’s researchers Laboratory, please visit the lab web site at http://www. are assessing the protection devices’ performance in vitro contrib.andrew.cmu.edu/~finol/. 2 3 iNews • Spring 2008 Newsletter BCI Effort brain computer interface research for impaired motor functioning Our BCI platform consists of two major sub-systems: (1) By Jeyanandh Paramesh, Assistant Professor of Electrical and signals and compresses them for wireless transmission. Computer Engineering When normal motor function is impaired by amputation, trauma or disease, it is necessary to use techniques such as prosthetics and wheelchairs to interact with the environment. However, the controllability of a patient a low-power integrated wireless micro-system and (2) a portable neural signal decoder. The wireless sub-system records extremely low-level neural signals from several (e.g., 32) electrodes, amplifies, filters and digitizes these A key trade-off in this design is to minimize its power consumption so that (1) heat dissipation does not cause biological damage and (2) it can operate from relatively small amounts of power that can be inductively coupled in from an external source. can be substantially limited by his impairments: e.g., a patient with spinal cord injury may not be able to control a wheelchair by hand. In this case, it is extremely important to develop a brain computer interface (BCI) for which neural signals from the brain are sensed, amplified, filtered and decoded to control prosthetic limbs, electric wheelchairs, or other external devices, leading to a dramatically improved quality of life. BCI is defined as the science and technology of intelligent devices and systems responding to (1) neural processes in the brain that generate motor movement and (2) cognitive process (e.g., memory) that modify motor movement. Today, with advanced technologies in medical sensors, biocompatible materials, integrated circuit and computational neurosciences, such a BCI system becomes practically feasible. There is a strong interest from industry to commercialize and market a BCI system for both medical Figure 1. BCI Platform An artist’s rendition of a state-of-the-art implanted wireless sub-system is shown in Fig. 1. Because this implant uses several discrete chips assembled on a printed circuit board, it is too large to be embedded in the skull as and non-medical applications. shown. Instead, it may have to be embedded in the larger There is currently a collaborative project being conducted clavicle. This would require long cables from the electrodes in BCI research between Carnegie Mellon’s Gary Fedder, Xin Li, and Jeyanandh Paramesh of the Electrical and Computer Engineering Department and Douglas Weber with the Department of Physical Medicine & Rehabilitation at the University of Pittsburgh School of Medicine. The major goal of our project is to develop a low-power wireless BCI micro-system. In particular, our project focuses on “minimally invasive” BCI technology using electrocorticography (ECoG) recorded from the cortical surface. ECoG has higher spatial resolution than EEG (electroencephalography) and is safer than single-neuron recording. The wireless interface proposed in this project has many advantages in terms of comfort and mobility. Most importantly, it reduces the risk of infection. cavity far away from the brain, for example, close to the to the implants and would raise concerns of infection. A second drawback with this system of Fig. 2a is that the circuits operate relatively inefficiently so that they require an on-implant battery. Ongoing work in our lab aims to find solutions to these problems. Their approach is to integrate all functions (amplification, filtering, digitization, compression and telemetry) on a tiny piece of silicon. This ultra-low power chip would be power using on-chip coils that couple inductively to a remote power source. Concurrently, several groups within CMU are collaborating on a largely biodegradable scaffold that will connect the electrodes to the implantable chip. Our group at CMU also collaborates with UPMC to develop robust, bio-compatible recording electrodes and test in-vivo these complex, engineered implants. ICES — The Institute for Complex Engineered Systems recording electrodes and test in-vivo these complex, engineered implants. Fenves Award dr. lee weiss is the 2007– 2008 recipient of the steven j. fenves award Robotics Institute Research Professor and ICES faculty member Lee Weiss was recently named the 2007– 08 recipient of the Steven J. Fenves Award. The Fenves Award is awarded annually to a faculty member who makes a significant contribution to systems research in areas relevant to ICES. This award will be presented to Dr. Weiss at the Carnegie Institute of Technology (CIT) Faculty Awards Banquet this spring. Dr. Weiss received the Fenves Award for his significant contributions to system engineering research in shape deposition manufacturing, micromechanical Velcro, inkjet printing technologies for biomedical applications and Fig. 2a. Artist’s rendition of the signal conditioning and the establishment of tissue engineering at Carnegie telemetry of a current neural implant and (b) the Neural Mellon. ICES Director Gary Fedder says, “Lee Weiss signal processor. embodies the very essence of the Steven J. Fenves Award The second sub-system (Fig. 2(b)) is a robust decoder that takes the recorded neural signal as input and accurately predicts the kinetic parameters (e.g., direction, velocity, etc.) of targeted movement. Instead of considering the neural signal decoding as a general signal processing problem, we particularly focus on the aspect of hardware implementation with high mobility. Namely, the algorithms used for neural signal decoding must be implemented in hardware with small dimension, light weight and low power. The long-term goal of this project is to develop advanced micro-system technologies and apply them to clinical applications. Through collaborations with several multidisciplinary groups with Carnegie Mellon, the University of Pittsburgh Medical Center (UPMC) and the Allegheny General Hospital, this project will eventually lead to intelligent devices and systems that aid disabled people and significantly improve the quality of their life. as reflected by his significant contributions to systems engineering research with an impact on the real world. His service of three-plus decades at Carnegie Mellon reflects his unparalleled quest for bringing people of different backgrounds together by trail blazing new areas.” Dr. Weiss has been a contributor to systems research since before the existence of ICES and the NSF EDRC (Engineering Design Research Center). “He has been the keeper of the spirit of ICES by reflecting its goals and by being an exemplar researcher for others to follow,” continues Dr. Fedder. The “Steven J. Fenves Award for Systems Research” is presented annually to individuals for their contributions to systems research in areas that are relevant to the College of Engineering and ICES. Individuals considered for this award have made significant contributions to systems research in areas relevant to ICES, by furthering the goal of interconnecting people, physical, and information; development and demonstration of an engineered system; enhancing education in systems through the development of courses, publishing textbooks, or a body of knowledge that is of pedagogical importance; and causing a paradigm shift in systems research. 4 5 iNews • Spring 2008 Newsletter New ICES Center ices introduces new interdisciplinary engineering center on multiscale modeling coordinate research and educational activity in multiscale materials modeling across the Carnegie Mellon Colleges of Engineering and Sciences. The vision of CM2EM is the quantitative understanding of materials from the smallest to the largest relevant scales, with a special emphasis on emergent behavior in complex materials systems, in order to enable the better design of applications with existing engineering materials and to engineer new Some important intellectual challenges of modern-day materials with targeted functionality. The center will science and technology deal with multiscale modeling serve to predict the properties and performance of for engineering materials. These challenges address existing engineering materials systems under varied issues such as fatigue in jet engine and electronic storage operational conditions as well as consider theoretical components; the design and reliability of microelectrical aspects of the design of new materials. It will serve mechanical systems (MEMS) devices; high-rate-deformation as a primary hub for materials modeling activity at in armor and weaponry; forming high strength and high Carnegie Mellon. Civil and Environmental Engineering ductility metallic alloys and metallic glasses for use in Professor Amit Acharya will be the Director of CM2EM, structural applications like auto-body parts and sports and Physics Professor Michael Widom from the Mellon equipment; and the high-frequency response in earthquake College of Science will act as the Associate Director. rupture dynamics, among others. To date, faculty participants in CM2EM hail from the following departments: Civil and Environmental Engineering, Electrical and Computer Engineering, Chemical Engineering, Materials Science and Engineering, Mechanical Engineering, Mathematics, and Physics. Professors (from l. to r.) Amit Acharya and Michael Widom. The mission goals of CM2EM include developing new theory and simulation tools for engineering and scientific Modern engineering technology manipulates the interaction applications that often require multiscale physics. of various materials at multiple scaling levels. The Examples of these applications include stress management macro-scale deals with the visible materials we see. A in metallic and semiconductor heterostructures, earthquake major emphasis of current research deals with smaller rupture dynamics, and the macroscopic response of levels of interaction within these materials, whether they metallic glasses. The emphasis of the research, however, be on the atomic and molecular scale in nanotechnology will be on engineering as well as on physics. Another or intermediate length scales as in MEMS research goal of CM2EM includes educating the next generation of and design. If one were to look under a microscope, students in engineering to be well-versed in such concepts however, it would become apparent that there are other as nonlinear continuum mechanics, relevant aspects of objects between the micro and macro scales which play statistical physics, and mathematics. Most importantly, the an important role. It is the goal of multi-scale modeling focus of CM2EM provides an essential niche which is not of materials to infer the laws that govern the interaction currently a part of training to deal with the challenges facing of materials at the coarser “meso-scales” using modern engineering. interdisciplinary tools from continuum mechanics, dynamical systems theory, statistical physics, and the theory of partial Activities of the center will include hosting a seminar differential equations. series, targeting research funding opportunities in focused groups, establishing industry collaboration, and phasing ICES Director Gary Fedder is pleased to announce the in an interdisciplinary curriculum in multiscale modeling, creation of a new Center for Multiscale Modeling for which includes new and existing courses in the Colleges of Engineering Materials (CM2EM) within ICES that will Engineering and Sciences. ICES — The Institute for Complex Engineered Systems Awards & Recognition honors & awards ICES Staff Members Win CIT Awards ICES is pleased to announce that staff members Christina Cowan, Alicia Brown, and Matthew Sanfilippo received awards at the annual Carnegie Institute of Technology (CIT) Staff Awards on January 31, 2008. Christina Cowan, who is the executive assistant to Director Gary Fedder, won this year’s CIT Staff Award and was selected based on the excellence she has shown in the areas of job performance, dedication, positive attitude, and contributions as a team player. Christina has worked at ICES for the past eight years and has been an invaluable part of the administrative team. Alicia Brown was awarded the Timothy J. Burritt Education ICES CIT Award winners (from l. to r.): Alicia Brown, Matt Award for balancing her pursuit of a Ph.D. in the social Sanfilippo, and Christina Cowan. and comparative analysis of education at the University of Pittsburgh with her position at ICES. Alicia began Culture Prize, given this year in the area of science. Dr. working at ICES in 2004 and was recently promoted to the Franchetti, who grew up in Wiener Neustadt in Austria, position of external relations and outreach coordinator. is one of two co-winners in the young scientist category. Matt Sanfilippo, who is the executive director of the This year’s submissions were judged by a five-member Center for Sensed Critical Infrastructure Research panel on the basis of scientific excellence and connection (CenSCIR), received the Rookie Award. Having worked at to Wiener Neustadt. ICES for less than two years, Matt received the award for demonstrating excellence in the areas of job performance, CenSCIR professors Jim Garrett and Lucio Soibelman dedication, positive attitude, and contributions as a team were recently selected to be co-editors-in-chief for the player in his short time with ICES. American Society of Civil Engineers (ASCE) Journal of Computing in Civil Engineering beginning in January of On January 1st of this year, ICES Director Gary Fedder was this year. They were selected by a national committee elevated to IEEE Fellow for his contributions to integrated and the journal is a leading publication in the area of micro-electro-mechanical-system processes and design computer research in civil engineering. methodologies. Each year, the IEEE (the Institute of Electrical and Electronics Engineers) Fellow Committee In 2007, Metin Sitti, associate professor in biomedical and recommends a select group of recipients to receive the title mechanical engineering, was appointed as the Adamson of Fellow, one of the Institute’s most prestigious honors. Career Faculty Fellow by the Department of Mechanical Engineering for a period of two years. He was named as Professor Fedder was awarded the IEEE Sensors fellow in recognition of his outstanding accomplishments Council’s 2007 Sensors Journal Best Paper Award for and promise in the areas of micro- and nanoscale robotics. his paper on “Electrostatically Actuated Resonant Microcantilever Beam in CMOS Technology for the Stefan Zappe, assistant professor of biomedical Detection of Chemical Weapons.” engineering and ICES affiliated faculty, has received a National Science Foundation (NSF) CAREER Award. Dr. CenSCIR faculty member and Electrical and Computer Zappe will receive $400,000 over a five-year period for use Engineering System Scientist Dr. Franz Franchetti is one in his research on “Automated MEMS-based Drosophila of five recipients of the City of Wiener Neustadt’s 2007 Article continued on page 10... 6 7 iNews • Spring 2008 Newsletter News Shorts ices news shorts This study aims to measure life stress, particularly the ICES Researchers’s NIH-Funded eWatch Study Receives Media Coverage ICES Research Professor Asim Smailagic, Director of the Human-Computer Interaction Institute Dan Siewiorek, and Pitt Psychology Professor Thomas Kamarck have received press coverage on the online news sources ScienceDaily and EurekAlert for their work studying the effectiveness of the eWatch, a wrist-mounted instrument, for measuring psychosocial stress exposure during the course of daily life. The eWatch is a multisensor package about the size of a large wristwatch, was developed by Professors Smailagic and Siewiorek and is one of the wearable products they have created in the Interaction Design Studio and Wearable Computers Lab, of which Dr. Smailagic is the director. Professors Smailagic, Siewiorek and Kamarck have received a $426,000 grant from the National Institutes of Health (NIH) for the first year of their four-year project, which is part of a larger NIH initiative – Genes, Environment and Health Initiative - to study environmental factors that people encounter every day that may increase their risk for certain diseases. duration or intensity of exposure to stress, by outfitting each participant in the study with an eWatch. The eWatch can detect sound, motion, lighting, and other factors. Every 45 minutes during a five day period, the eWatch prompts wearers to take part in a brief interview, recording their responses to questions about their current events. The eWatch was first developed as a class project in Drs. Smailagic and Siewiorek’s Rapid Design and Prototyping course in 2004. The development and refinement of the eWatch was made possible by Pennsylvania Infrastructure Technology Alliance (PITA) funding. This funding also allowed for the continued collaboration of the LINCS lab work with local industry including BodyMedia, a company specializing in wearable biometric data collection devices, Inmedius, Intel, Bosch, and R.J. Lee Group. Over the last decade the Interaction Design Studio and Wearable Computers Lab have collaborated in design and prototyping of more than 30 wearable and context aware systems, which have become cornerstones of the wearable computing field. For more information on the eWatch or on the work done by the Interaction Design Studio and Wearable Computers Lab, please contact Professor Smailagic at asim @ cs.cmu.edu or Professor Siewiorek at dps @ cs.cmu.edu. Burcu Akinci’s Research on Construction Project Control Is Featured Associate Professor of Civil and Environmental Engineering and CenSCIR member Burcu Akinci’s work on active quality control of construction projects and accurate documentation of project history was featured in the Spar Point Research on-line articles. Participants in the project, Advanced Sensor-Based Defect Management at Construction Sites (ASDMCon), draw from the Civil and Environmental Engineering department, the School of Architecture, and the Robotics Institute, and many of the key participants are active members of CenSCIR. The project developed work processes that use integrated project models, 3D laser scanners and embedded sensor systems for early defect detection and management at construction sites. For more information, please contact Professor Akinci at bakinci@cmu.edu. ICES — The Institute for Complex Engineered Systems News Shorts dowd fellowship news 2007 Dowd-ICES Fellow and Civil and Environmental En- gineering graduate student Saurabh Puri and his advisor Professor Amit Acharya are in the process of submitting a paper that is based on research funded by the Philip and Marsha Dowd Fellowship Seed Fund. Puri’s Dowd-funded research is on strength, internal stress, and relaxation in mesoscale plasticity. The goals are to understand mechanical response at the micron scale for microelectromechanical (MEMS) devices and also to understand the stress relaxation in stamped aluminum sheets in order to optimize the production of auto-body panels leading to light 2007– 08 ICES-Dowd Fellows (from l. to r.): Sasha Bakhru, weighting. The effect of this is to improve fuel efficiency Saurabh Puri, Rowena Mittal, and Warren Ruder. and reduce greenhouse gas emissions in automobiles. SURE Thing Student’s Research to be Represented Artificially designed cell factories have the ability to at the IEEE International Conference respond to a localized health threat by targeting the ap- The research that SURE Thing 2007 student Michael Wahl propriate region of the body affected by a medical condi- conducted with his faculty advisors and Electrical and tion and then manufacturing and delivering a biological Computer Engineering faculty Yuanwei Jin and Jose M.F. product to treat the condition over an extended period. In Moura will be represented in a paper at the 5th Institute January, 2007 Dowd-ICES Fellow and Biomedical Engineer- of Electrical and Electronics Engineers (IEEE) International ing graduate student Warren Ruder published an article Symposium on Biomedical Imaging: From Nano to Macro. in Trends in Biotechnology on artificial cell research, which The IEEE conference will be held in May in Paris, France, he co-authored with his advisor and Associate Professor in and his advisors will be presenting their paper on “Breast Biological Sciences and Mechanical Engineering profes- Cancer Detection by Time Reversal Imaging.” Co-authors sor Philip LeDuc, and Postdoctoral Research Associate in on the article were Wahl, Jin, Moura, and a colleague from Mechanical Engineering Ying Zhang. Their article entitled the University of Pittsburgh Medical Center. “Artificial Cells: Building Bioinspired Systems Using SmallScale Biology” is based on PITA-funded research that uses Wahl, an undergraduate student in chemical engineering and converts naturally available molecules in the body into at the University of Pittsburgh, worked with Professors active therapeutics by designing artificial cell factories. Jin and Moura on time reversal beamforming for electromagnetic methods of detecting breast cancer. He In the last year, 2004 Dowd-ICES Fellow Bahareh Behkam’s had an opportunity to model the electrical differences research with Associate Professor and Adamson Career between malignant breast tumors and normal breast Faculty Fellow Metin Sitti has received follow-on funding tissue through different materials to show the potential from the National Science Foundation (NSF) as well as of the time reversal microwave breast cancer detection media coverage. Their research on propulsion systems system. For more information on the SURE Thing summer for miniature swimming robots used medically has ap- internship program, please visit http://www.ices.cmu. peared in New Scientist and on-line on Discovery News edu/sure-thing/. and Nanowerk. Sitti, who is a professor in both Mechanical Engineering and the Robotics Institute, and Bekham have worked on the challenge of developing the power and propulsion of microscale robots. In their research, they have taken a novel approach by using the entire microorganism as the motor and controlling its on/off motor with chemicals. 8 9 iNews • Spring 2008 Newsletter Enterprise-Wide Optimization pita collaboration develops enterprise-wide optimization for industry competitiveness The research work at ICES in EWO is performed by a By Ignacio Grossmann, Rudolph R. and Florence Dean University Professor of Chemical Engineering Enterprise-wide optimization (EWO) has become a major goal in this industry due to the increasing pressure for remaining competitive in the global marketplace. EWO involves optimizing the operations of supply, manufacturing and distribution activities of a company to reduce costs and inventories. One of the key features in EWO is integration of the information and decision-making among the various functions that comprise the supply chain of the company. multidisciplinary team from three Pennsylvania institutions (Larry Biegler, Ignacio Grossmann, John Hooker from Carnegie Mellon, Larry Snyder from Lehigh University, Jeff Linderoth from the University of Wisconsin, Andrew Schaefer from the University of Pittsburgh), composed of chemical and industrial engineers, and operations researchers, (five faculty, eight Ph.D. students). The group is developing novel models, algorithms, decomposition methods, and computational techniques, and involves close collaborations with industry, including ABB, Air Products and Chemicals, BP, Dow Chemical, ExxonMobil, NOVA Chemicals and TOTAL who are members of the Center for Advanced Process Decision-making (CAPD) at Carnegie Mellon. Air Products and Chemicals, and NOVA Chemicals are both headquartered in Pennsylvania. This collaborative research project was initiated in July 2005 and continues with the aid of Pennsylvania Technology Alliance (PITA) funding. It has also since received supplementary funding from the National Science Foundation (NSF). The current research work involves the scheduling of cranes in steel manufacturing (ABB), rescheduling of bulk gas production and distribution (Air Products), optimization models for planning of refinery operations (BP), simultaneous strategic and tactical planning in distributed batch plants (Dow), global optimization of multiperiod refinery models (ExxonMobil), modeling and evaluation platform for a specialty polymer product (NOVA), and crude oil scheduling (TOTAL). The EWO group meets Coordinated optimization of supply manufacturing and twice per year, and organizes a popular seminar series distribution across a supply chain. that is broadcast to the companies. Research results are available on the webpage http://egon.cheme.cmu. To fully realize the potential of IT transactional tools, the edu/ewocp/. The new computational tools in EWO have development of sophisticated deterministic and stochastic demonstrated the potential economic savings that can linear/nonlinear optimization models and algorithms be achieved through a systematic application of these (analytical IT tools) is needed to explore and analyze computational techniques, and in some cases they are alternatives of the supply chain to yield overall optimum being adopted by the companies. economic performance, as well as high level of customer satisfaction. An additional challenge is the integrated and For more information about this project, please contact coordinated decision-making across the various functions in Professor Grossmann at grossmann @ cmu.edu. a company (purchasing, manufacturing, distribution, sales), across various geographically distributed organizations (vendors, facilities and markets), and across various levels of decision-making (strategic, tactical and operational). ICES — The Institute for Complex Engineered Systems PITA Highlights pita project news Article Examines Combining Profitability and Student Receives Yahoo! Grant for Environmentally Friendly Electricity Production PITA Blog Research As of 2007, there are only two integrated gasification Computer science professor Christos Faloutsos’s graduate combined cycle (IGCC) energy plants in the United student Mary McGlohon recently received a Key Technical States. Yet, the process used by this facility is Challenges Grant from Yahoo! The Key Technical more environmentally friendly than other coal-fueled Challenges Program is a new Yahoo! program that technologies such as pulverized coal facilities in the provides a limited number of exceptional Ph.D. students way it separates the CO2 in the process as it captures with $5,000 each of unrestricted funds for the support of and stores the carbon. The PITA-supported research of their research activities. Engineering and Public Policy and Tepper School Professor Jay Apt and Engineering and Public Policy graduate Ms. McGlohon will use this funding for research she student Adam Newcomer looks at producing electricity is conducting with Dr. Faloutsos in blog analysis. This from coal-derived synthesis gas (syngas) in an integrated 2007 PITA-funded project, entitled “Influence Propagation gasification combined cycle facility. They have recently in Large, Blog Graphs,” analyzes blogs as a social published their work in the December 2007 issue of the phenomenon which often influence political opinions journal Environmental Science & Technology. and create market or opinion trends. The goal of their research is to ultimately forecast which trends will While producing electricity in this way is more prevail by looking for patterns of how blog citations environmentally friendly than other methods, it is not appear over time and classifying them. This project profitable when the carbon dioxide price is less than collaborates with the Pittsburgh office of Nielsen approximately $50 per metric ton. In their article, Apt BuzzMetrics, which conducts media measurement using and Newcomer examine whether such a facility that data-mining technology. operates its gasifier continuously but stores the syngas and produces electricity only when daily prices are high may be profitable at significantly lower CO2 prices. ices honors ...Continued from page 6. Dr. Apt is also the Executive Director of the Electricity Embryo Injection Technologies for High-throughput Func- Industry Center, which employs interdisciplinary tional Genomics Screens.” The Faculty Early Career De- approaches to the problems of the electricity industry velopment (CAREER) Program is a Foundation-wide activity and merges engineering, economics, risk analysis, and that offers the National Science Foundation’s most pres- decision science. tigious awards in support of the early career-development activities of those teacher-scholars who most effectively integrate research and education within the context of the mission of their organization. 10 11 iNews • Spring 2008 Newsletter PITA Highlights outreach update ICES Outreach Receives Media Attention during National Engineers Week On February 15 and 16, ICES participated with other Carnegie Mellon departments and local organizations in the National Engineers Week outreach activities at the Carnegie Science Center. The ICES table was manned during these days by ICES faculty, staff, and students who worked with visiting children on the activity “Build a Bone.” This problem-solving activity gives participants a list of materials and parameters they must follow as they attempt to create a bone that will hold the most weight when tested. This year, a new record was set for the strongest bone, which held 24 lbs, and it resulted in attracting the media attention of WQED’s Rick Sebak. Sebak, who creates documentaries about Pittsburgh history, was filming at the Science Center on Friday for a new documentary called “Invented, Engineered, and Pioneered in Pittsburgh.” His film crew captured on tape the testing of the strongest bone by its young creator and by ICES Associate Research Professor Phil Campbell, who was working at the ICES table. Professor Campbell created the Build a Bone activity for National Engineers Week and is the ICES faculty coordinator for National Engineers Week activities at the Science Center. The documentary will premiere on WQED on Thursday, April 10. ICES — The Institute for Complex Engineered Systems Closing Notes upcoming ices events iNews is the official publication of the Institute for Com- moving 4th into engineering Saturday, April 5th For more information, please visit: http://www.ices.cmu.edu/moving_4th.html censcir symposium Tuesday, May 6th Singleton Room, Roberts Hall For more information, please visit: http://www.ices.cmu.edu/censcir pita advisory board meeting In May, Date TBD Lehigh University For more information, please visit: http://www.pitapa.org summer undergraduate research experience (a sure thing!) May 28th - August 1st plex Engineered Systems (ICES). To submit information for the next edition of iNews or to join our mailing list, please contact Alicia Brown at adbrown @ andrew.cmu.edu. Editor and Writer: Alicia Brown Designer: tim kelly Photography: daniel shapiro, ken andreyo, and tim kelly Contributing Writers: amit acharya, nichole dwyer (cee newsletter), ender finol, ignacio grossman, jeyanandh paramesh, matthew sanfilippo, and michael widom Printing: Network printing services To read more about ICES, its current structure, research interests, projects, and people, please visit our newly redesigned website at http://www.ices.cmu.edu/. Please feel free to contact our director, Gary Fedder, or use our on-line directory to identify contacts. We welcome your comments and your ideas. Carnegie Mellon University does not discriminate and Carnegie Mellon University is required not to For more information, please visit: discriminate in admission, employment or administration of its programs or activities on the basis http://www.ices.cmu.edu/sure-thing Title IX of the Educational Amendments of 1972 and Section 504 of the Rehabilitation Act of 1973 summer engineering experience (see) for girls of race, color, national origin, sex or handicap in violation of Title VI of the Civil Rights Act of 1964, or other federal, state, or local laws or executive orders. In addition, Carnegie Mellon University does not discriminate in admission, employment or administration of its programs on the basis of religion, creed, ancestry, belief, age, veteran status, sexual July 14th - July 25th orientation or in violation of federal, state or local laws or executive orders. However, in the judgment For more information, please visit: ask, don’t tell, don’t pursue” excludes openly gay, lesbian and bisexual students from receiving http://www.ices.cmu.edu/see of the Carnegie Mellon Human Relations Commission, the Department of Defense policy of, “Don’t ROTC scholarships or serving in the military. Nevertheless, all ROTC classes at Carnegie Mellon University are available to all students. Inquiries concerning application of these statements should be directed to the Provost, Carnegie Mellon University, 5000 Forbes Ave., Pittsburgh, Pa. 15213, telephone 412-268-6684 or the Vice President for Enrollment, Carnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, Pa. 15213, telephone 412-268-2056. Copyright © Carnegie Mellon University. Carnegie Mellon University publishes an annual campus security report describing the university’s security, alcohol and drug, and sexual assault policies and containing statistics about the number and type of crimes committed on the campus during the preceding three years. You can obtain a copy by contacting the Carnegie Mellon Police Department at 412-268-2323. The security report is available through the World Wide Web at www.cmu.edu/police/statistics.htm. Obtain general information about Carnegie Mellon University by calling 412-268-2000. 12 PITA is a Pennsylvania Department of Community and Economic Development (DCED) program designed to provide economic benefit to Pennsylvania through knowledge transfer, the discovery of new technologies, and the retention of highly educated students. fiscal year 2008 pita funded projects at carnegie mellon For the Fiscal Year 2008, the Pennsylvania Infrastructure Technology Alliance (PITA), through ICES, recently funded 33 It is a collaboration between the Commonwealth of projects at Carnegie Mellon out of a total of 66 submitted Pennsylvania, the Center for Advanced Technology for Large proposals. The accepted projects encourage multidisciplinary Structural Systems (ATLSS) at Lehigh University, and the research across the College of Engineering departments, the Institute for Complex Engineered Systems (ICES) at Carnegie Tepper School of Business, and the Robotics Institute. Mellon University. The research areas funded by PITA include: PITA’s research and education projects involve Pennsylvania companies, faculty, and students. PITA’s programs have led 30% in biomedical and health engineering; 21% in product/process design and optimization; to the creation and implementation of numerous cutting-edge 12% for courses and outreach programs; technologies in Pennsylvania companies and have also enabled 12% in infrastructure safety and security technology; several start-up companies to form within the Commonwealth. 12% in nanotechnology; 6% in environmental technologies; for more information, please visit the pita website at www.pitapa.org or call 412-268 -3372 Gary Fedder, PITA Co-Director Matthew Sanfilippo, PITA Co-Associate Director (ICES) Institute for Complex Engineered Systems Carnegie Mellon University Richard Sause, PITA Co-Director Robert Alpago, PITA Co-Associate Director ATLSS Engineering Research Center Lehigh University 3% in innovative infrastructure system assessment technology; and 3% in information and systems technology.