Program Book

Transcription

Program Book

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ACNP
AMERICAN COLLEGE OF NEUROPSYCHOPHARMACOLOGY
44th
ANNUAL MEETING
GENERAL
PROGRAM
WAIKOLOA, HAWAII
HILTON WAIKOLOA VILLAGE
DECEMBER 11-15, 2005
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Table of Contents
Acknowledgments . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1
Council . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2
Program Committee . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2
Dates and Location . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3
Book of Abstracts . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3
Program Book . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3
Abstracts-On-Line . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3
Abstracts-On-CD . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3
Executive Office . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3
Continuing Medical Education (CME) . . . . . . . . . . . . . . . . . . . . . 4
Meeting Evaluation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5
Scientific Program
Videotaping Sessions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5
Teaching Day . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5
Hot Topics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5
Oakley Ray History Lecture . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6
President’s Plenary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6
Distinguished Lecture . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6
Issues in Ethics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6
Panels (times and dates) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7
Study Groups (times and dates) . . . . . . . . . . . . . . . . . . . . . . . . . 7
Posters Sessions (times and dates) . . . . . . . . . . . . . . . . . . . . . . . 7
Registration . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8
Hotel Facilities . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9
Insurance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9
Services . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10
Refreshments Breaks . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10
Buffet Meals . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11
Reception . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11
Special Events . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11
College Meetings . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13
Committee/Task Force Meetings . . . . . . . . . . . . . . . . . . . . . . . . . 14
Sanctioned Meetings . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16
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Program Listings
Sunday, December 11th
Teaching Day . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23
Hot Topics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24
Oakley Ray History Lecture . . . . . . . . . . . . . . . . . . . . . . . . . . . 28
Monday, December 12th
President’s Plenary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29
Distinguished Lecture . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30
Afternoon Panel Sessions
Dopamine Beta Hydroxylase Genetics and Substance
Abuse: Of Mice and Men . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 31
Specificity of Cortical GABAergic Systems: Development
and Disturbances in Schizophrenia . . . . . . . . . . . . . . . . . . . . . . . . 32
Homo- and Hetero-Dimerization of G Protein-Coupled
Receptors: Drug Mechanisms and Pharmacological
Diversity. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33
Successful Aging: A Neuropsychiatric Entity . . . . . . . . . . . . . . . 34
Towards Building Translational Measures of Depression:
Objective Characterizations of Depressive Phenotypes and
Biomarkers in Humans and Animals . . . . . . . . . . . . . . . . . . . . . . 35
Effects of Immune Mediators on the Development of
Brain Circuits Regulating Cognition and Emotion . . . . . . . . . . . 36
Genes and Brain Development in Health and Illness: The
Trajectory is the Story . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37
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Monday, December 12th (cont’d)
The Future of Phase IV Studies and Off-Label Prescribing:
The Conundrum Facing Corporate Sponsors of Research,
Regulators, Clinical Investigators and the Future of
Psychiatric Practice . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38
Study Groups
Developing a Consortium and Mechanism to Facilitate the
Development of Radiotracers as Useful Biomarkers in
Academia and Industry . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39
J’Accuse: COI in the News, but What of the Accused? . . . . . . . . 40
Tuesday, December 13th
Morning Panel Sessions
Animal Models of Schizophrenia: Making Progress or
Just a Delusion? . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41
Noradrenergic and Dopaminergic Modulation of
Prefrontal Cognition . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 42
Steroid Hormones and Addiction: From Genes to
Behavior . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 43
Drug Development: Biomarkers in Alzheimer’s Disease:
Early Diagnostic and Treatment Implications . . . . . . . . . . . . . . . 44
The Prefrontal Cortex and Cognitive Flexibility . . . . . . . . . . . . . 45
Stress, Pain and Emotions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 46
New Neuroimaging Findings in the Pathophysiology and
Treatment of Panic Disorder . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47
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Tuesday, December 13th (cont’d)
ECNP Panel: Bipolar Disorders: European Contributions . . . . . . 48
Issues in Ethics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49
Lipid Rafts, Caveolin-Related Proteins and Neuronal
Signaling . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 50
JSNP Panel: Molecular Mechanisms of Drug Dependence
Induced by Amphetamine and Related Drugs . . . . . . . . . . . . . . . 51
What Does Dopamine Say: Clues from Computational
Modeling . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 52
The Role of Feeding Neuropeptides in Alcohol and Drug
Dependence . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 53
Drug Development: Development of Novel Metabotropic
Glutamate Receptor Agents for the Treatment of
Schizophrenia and Anxiety-Related Disorders . . . . . . . . . . . . . . . 54
Drug Development: Practical Clinical Trials of
Antipsychotic Drugs in Schizophrenia . . . . . . . . . . . . . . . . . . . . . 55
Corticolimbic Changes in Bipolar Disorder: A
Developmental Perspective . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 56
Novel Pharmacological Approaches to the Treatment of
Drug Addiction: Animal and Human Studies . . . . . . . . . . . . . . . . 57
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Wednesday, December 14th
The Warrior/Worrier Paradox: Varying Allelic Effects and
Counter Balancing Selection of Phenotypes . . . . . . . . . . . . . . . . 58
Subregions in the Medial Temporal Lobe: Implications
for Normal and Disordered Cognition . . . . . . . . . . . . . . . . . . . . . 59
Drug Development: GSK-3: A Novel Target for Improved
Therapeutics for Severe Neuropsychiatric Diseases . . . . . . . . . . 60
Validation of Screening Models for Medications
Development to Alcoholism . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 61
Is it Worth the Risks? Treating the Elderly with
Antipsychotics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 62
Neuregulin and Schizophrenia: From Genetic Sequence to
Pathogenic Mechanisms . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 63
Animal Models of Deficient Sensorimotor Gating:
A New Role for the Corticotropin-Releasing Factor
System? . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 64
Molecular Mechanisms of Synaptic Alterations Associated
with Neuropsychiatric Disorders and Addiction . . . . . . . . . . . . . 65
Tourette Syndrome-A Window into Neurochemistry and
Neuropharmacology of Many Comorbid Neuropsychiatric
Disorders . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 66
Drug Development: Advances in Neurotensin
Neurobiology: Implications for Novel Treatments for
Psychosis and Drug Abuse . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 67
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Wednesday, December 14th (cont’d)
Cortical Dopaminergic Neurotransmission and Cognition:
Neuroimaging and Physiologic Studies . . . . . . . . . . . . . . . . . . . . 68
Protein Trafficking and Therapeutic Mechanisms for
Mood Disorders . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 69
5-HT6 Receptors: New Targets for Neuropsychiatric
Disorders . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 70
Stress in Addiction Relapse: Are There Viable Treatment
Targets? . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 71
Thursday, December 15th
Selecting Animal Models to Predict Pro-Cognitive Effects
in Human Populations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 72
Synaptic Plasticity: Focus on the Mechanisms and Clinical
Implications of Long-Term Depression . . . . . . . . . . . . . . . . . . . . 73
Advances in Functional Neuroanatomy and
Neurochemistry of Resilience . . . . . . . . . . . . . . . . . . . . . . . . . . . 74
If You Prick Them, Do They not Bleed? Emotion
Recognition and Schizophrenia . . . . . . . . . . . . . . . . . . . . . . . . . . 75
Clock Genes, Melatonin and Affective Disorders . . . . . . . . . . . . 76
The Endocannabinoid System as Target for Drug
Discovery . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 77
A Noradrenergic Focus on Attention and Attention-Deficit
Disorders . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 78
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Thursday, December 15th (cont’d)
Teaching Neuropsychopharmacology . . . . . . . . . . . . . . . . . . . 79
Plastic Changes in the Addicted Brain: A Glimpse at the
Next Generation of Pharmacotherapies . . . . . . . . . . . . . . . . . . . . 80
Neural Changes in Adolescence and Onset of
Schizophrenia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 81
Neuregulin 1 - ErbB4 Signaling in Schizophrenia . . . . . . . . . . . . 82
Drug Development: Novel Insights into the Neurobiology
and Treatment of Autism Spectrum Disorders . . . . . . . . . . . . . . . 83
Neural Mechanisms of Extinction: Translating from Rats
to Humans . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 84
Sex Differences in the Action of Opioids . . . . . . . . . . . . . . . . . . . 85
Whole Genome Association Studies: New Promise for
Psychiatric Genetics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 86
Poster Sessions
Poster Session I . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 89
Poster Session II . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 111
Poster Session III . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 134
Nonmember Participants List . . . . . . . . . . . . . . . . . . . . . . . . . . . 159
Appendix . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 173
Author Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 191
Hotel Map . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 222
Future ACNP Annual Meetings . . . . . . . . . . . . . . Inside Back Cover
Summary Program . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Back Cover
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ACKNOWLEDGMENTS
The American College of Neuropsychopharmacology gratefully acknowledges the following companies in support of the 44th ACNP Annual Meeting:
Bristol-Myers Squibb Company
Cyberonics, Inc.
Eli Lilly and Company
Forest Laboratories
GlaxoSmithKline
Janssen Pharmaceutica Products, L.P.
Otsuka Maryland Research
Pfizer Pharmaceuticals
Wyeth Pharmaceuticals
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COUNCIL
Officers and Council
President
President-Elect
Secretary
Treasurer
Daniel R. Weinberger
Kenneth L. Davis
Oakley S. Ray
Irwin J. Kopin
Council
William T. Carpenter, Jr.
Dennis S. Charney
Michael Davis
Ellen Frank
Raquel Gur
Mary Jeanne Kreek
Eric J. Nestler
Carol A. Tamminga
PROGRAM COMMITTEE
2005 Program and Scientific Communications Committee
Chair
Co-Chair
Council Liaison
Trey Sunderland
Larry Siever
Raquel Gur
Members
Lori Altshuler
Nancy Andreasen
Jay Baraban
Karen Berman
Jacqueline Crawley
John Csernansky
Steven DeKosky
David Goldman
Suzanne Haber
Dilip Jeste
Edward Jones
John Krystal
Pat Levitt
Edythe London
Helen Mayberg
Bruce McEwen
Charles Nemeroff
Daniel Pine
Judith Rapoport
Perry Renshaw
Lorna Role
Gary Small
Rita Valentino
Elizabeth Young
George Zubenko
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GENERAL INFORMATION
Dates and Location
Dates
Location
Sunday, December 11, 2005 - Thursday, December 15, 2005
Hilton Waikoloa Village, Waikoloa, Hawaii
Book of Abstracts
The abstracts presented at the Annual Meeting will be archival. All scientific registrants will receive a copy of Neuropsychopharmacology, Volume 30,
Supplement 1, December 2005 as part of their registration material.
Additional copies may be purchased from Nature Publishing Group
(http://www.nature.com/npp) for $30.00 each.
Program Book
All scientific registrants will receive a Program Book as part of their registration material. The Program Book is also available on the ACNP website,
www.acnp.org.
Abstracts-On-Line
All scientific registrants will be able to access the 44th ACNP Annual
Meeting Abstracts-On-Line at www.acnp.org.
Abstracts-On-CD
All scientific registrants will receive the 44th ACNP Annual Meeting
Abstracts-on-CD as part of their registration material.
ACNP Executive Office
ACNP Executive Office
545 Mainstream Drive, Suite 110
Nashville, Tennessee 37228
Phone: 615-324-2360
Fax:
615-324-2361
E-mail: acnp@acnp.org
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Continuing Medical Education
The 2005 ACNP Annual Meeting is jointly sponsored by the ACNP and
Vanderbilt University School of Medicine. This activity has been planned and
implemented in accordance with the Essential Areas and Policies of the
Accreditation Council for CME (ACCME) through the joint sponsorship of
Vanderbilt University School of Medicine and ACNP. Vanderbilt University
School of Medicine is accredited by the Accreditation Council for CME to
sponsor continuing medical education for physicians. Vanderbilt School of
Medicine designates this educational activity for up to 42.0 Category 1 credits toward the AMA Physician’s Recognition Award. Each physician should
claim only those hours of credit that he/she actually spent in the educational
activity. There is no charge for scientific registrants to obtain CME credits.
Current guidelines of the Accreditation Council for CME require that participants in CME activities must be made aware of any affiliation or financial
relationship that might influence a speaker’s presentation(s). To meet these
guidelines, each speaker was required to complete a “Financial Disclosure
Form.” Information that speakers provide on these forms is included in the
appendix of the Program Book.
The 2005 ACNP Annual Meeting has been planned to meet the educational
needs of the membership of the American College of Neuropsychopharmacology. Invited guests of members and trainees may also attend.
Learning Objectives:
After participating in the 2005 ACNP Annual Meeting, ACNP members
should be able to describe and discuss:
• recent theories about the treatment of mental and addictive disorders
• recent advances in basic neurosciences that affect the development of
new treatments
• recent progress in the molecular genetics and molecular biology of mental
and addictive disorders
• anatomical areas of the brain that are involved in the medication of behavioral states
• functional and anatomical brain abnormalities observed in recent studies of
mental and addictive disorders
CME forms and instructions are included in the meeting registration tote bag.
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Meeting Evaluation
All meeting attendees are urged to complete an evaluation of the meeting.
Attendees who are requesting CME credit for the meeting a re re q u i red to
complete the evaluation. You may complete the evaluation in the ACNP
Computer Center in Kona 2 or on-line at www.acnp.org (click Annual
Meeting). All evaluations must be completed by January 15, 2006.
SCIENTIFIC PROGRAM
VIDEOTAPING SESSIONS
Attendees may not videotape, audiotape, or photograph (camera or camera
phone) presentations at the Annual Meeting without prior permission from
the panel chair.
PLENARY SESSIONS
TEACHING DAY. Teaching Day is organized and chaired by Kenneth Davis,
the President-Elect. The topic this year is “Total Glia.”
8:00 a.m. - 12:30 p.m.
This session is located in the Monarchy Ballroom.
HOT TOPICS. Each presentation should last about ten minutes with a fiveminute period for questions and open discussion. There are two categories:
Basic/Translational topics & Clinical topics. The two sessions will be concurrent.
2:30 p.m. - 5:00 p.m.
Basic
Clinical
Kona 5
Kona 4
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OAKLEY RAY HISTORY LECTURE. This will be the first year of the biennial Oakley Ray History Lecture. This lecture will be chaired by Carl
Salzman, the History Committee Chair. Andrea Tone will be speaking on
“Fifty Years After Miltown: Tranquilizers, History, and Psychiatry.”
7:00 p.m. - 8:00 p.m.
This session is located in Kona 4.
PRESIDENT’S PLENARY. This year’s President's Plenary, chaired by ACNP
President, Daniel Weinberger, is titled “The Complexity of Complex
Genetics: Beyond Genes and Environment.”
8:00 a.m. - 11:30 a.m.
DISTINGUISHED LECTURE. This plenary is chaired by Daniel Weinberger.
The lecture will be presented by Ronald McKay. The title of his talk is,
“Stem Cells Today and Stem Cells Tomorrow.”
1:00 p.m. - 2:15 p.m.
ISSUES IN ETHICS. This year’s topic is “Rethinking Risk in Clinical
Research” and is co-chaired by David Rubinow and David Braff. The speakers this year include Paul Andreason, David Brent, James Harris, Lydia
Lewis, Jane Pearson, and Donald Rosenstein.
12:00 p.m. - 2:30 p.m.
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CONCURRENT SESSIONS
PANELS. The title and location of each Panel is indicated in the Program.
The presentations in each session are scheduled at approximately 30-minute
intervals, allowing for 20-minute presentations and 10-minute discussion
periods. A thirty-minute general discussion period is scheduled after the last
presenter in each session. Panels are scheduled:
2:30 p.m. - 5:00 p.m.
8:00 a.m. - 10:30 a.m.
2:30 p.m. - 5:00 p.m.
8:00 a.m. - 10:30 a.m.
2:30 p.m. - 5:00 p.m.
8:00 a.m. - 10:30 a.m.
2:30 p.m. - 5:00 p.m.
STUDY GROUPS. This year will be the first year of Issue Oriented Study
Groups. There are two study groups scheduled for Monday evening. The title
and location of each Study Group is indicated in the Program. They are:
7:45 p.m. - 9:00 p.m.
POSTER SESSIONS
POSTERS. Poster presentations are grouped by general topic area. Topic
areas are sometimes repeated. All three Poster Sessions are located in the
Kohala Ballroom.
5:30 p.m. - 7:30 p.m.
Poster Session I
Welcoming Reception
5:30 p.m. - 7:30 p.m.
Poster Session II
Reception
5:30 p.m. - 7:30 p.m.
Poster Session III
Reception
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REGISTRATION
ON-SITE REGISTRATION PERIODS
Date
Time
Location
Saturday, December 10th
10:00 a.m. - 6:00 p.m.
Kona 3
7:00 a.m. - 5:00 p.m.
Kona 3
7:00 a.m. - 5:00 p.m.
Kona 3
7:30 a.m. - 5:00 p.m.
Kona 3
7:30 a.m. - 5:00 p.m.
Kona 3
7:30 a.m. - 3:00 p.m.
Kona 3
ON-SITE REGISTRATION FEES
Categories
On-Site Fee
Members of ACNP
Members of ECNP, CINP, CCNP, JSNP (on list)
Emeritus
Corporate Representatives
Non-Member Program Participant
2005 Travel Awardees
Trainee*
Invited Guest
Past Travel Awardee (2003-2004)
Optional Journal Subscription for non-ACNP members**
Accompanying Person***
$450
$450
$250
$650
Waived
Waived
$250
$650
$250
$100
$125
*A Trainee is a person in a training position and not a full-time, permanent
position. A Trainee can be a M.D., Ph.D., Postdoctoral Fellow, or a Resident
Research Fellow. Trainees have all the rights and privileges of Invited Guests.
**Non-ACNP members may pay $100 extra and receive a 1-year subscription
(calendar year 2006) to Neuropsychopharmacology. This is a substantial discount from the normal non-member rate of $245.
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***An accompanying person is a spouse, relative, or significant other who
accompanies an attendee. An accompanying person may only attend the
social functions of the meeting, which includes the networking breakfast,
morning buffets, lunches, and the closing reception dinner. Accompanying
persons are also allowed to attend the poster sessions.
Registration fee for scientific registrants includes:
- Meeting refreshment breaks
- Admission to Teaching Day, Hot Topics, Issues in Ethics Session,
President’s Plenary, the Distinguished Lecture, Oakley Ray
History Lecture, Teaching Neuropsychopharmacology, all
panel & study group sessions
- Admission to poster sessions
- Admission to the Buffet Luncheons on Monday, Tuesday,
Wednesday
- Meeting Abstract Book, Program Book, and Abstracts-On-CD
- Registration packet containing CME instructions, other meeting
materials
- Thursday Evening Reception
Pre-paid registration will be outside of Waikoloa 1.
Hotel Facilities
The Hilton Waikoloa Village guest rooms, common areas, and transportation
services are in compliance with the public accommodation requirements of
the Americans with Disabilities Act. These facilities will be accessible to and
usable by individuals with disabilities who attend and participate in the
Annual Meeting.
Meeting and activity rooms have been designated smoke-free for the duration
of the Annual Meeting.
Insurance
It is highly recommended that all participants carry the proper travel and
health insurance as the ACNP cannot accept liability for any accidents or
injuries that may occur at the meeting.
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SERVICES
ACNP Service Center
The “Office Away from the Office” is provided for the convenience of meeting attendees. The Service Center will feature a message center, fax transmissions, and photocopying.
Kona 3:
Saturday (registration only)
Sunday-Monday
Tuesday-Wednesday
Thursday
10:00 a.m. - 6:00 p.m.
7:00 a.m. - 5:00 p.m.
7:30 a.m. - 5:00 p.m.
7:30 a.m. - 5:30 p.m.
ACNP Computer Center
The ACNP Computer Center is provided this year for the convenience of
meeting attendees. The computers will available for the following: abstractson-CD, e-mail, internet access, and meeting evaluation.
Kona 2:
Sunday through Wednesday
Thursday
7:30 a.m. - 9:00 p.m.
7:30 a.m. - 5:00 p.m.
Speaker Ready Room
A speaker ready room will be available in Kona 1. The speaker ready room
will be open Sunday - Thursday, 6:30 a.m. - 6:00 p.m.
Travel Information Desk
The Travel Information Desk is located outside of Queen’s 4 and is staffed by
Sailair Travel, Inc., the official travel agency for the ACNP. Participants can
obtain travel, tour, and car rental information, purchase tickets, and make a
variety of other tour and travel arrangements at this desk.
REFRESHMENT BREAKS
All registered individuals are invited.
Coffee and light pastries for registered individuals will be available in Lagoon
Lanai the following times:
Sunday, Monday, Tuesday, Thursday:
Wednesday:
7:00 a.m.
6:45 a.m.
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BUFFET MEALS
Date: Monday, December 12th
Time: 11:30 a.m. - 12:45 p.m.
Place: Lagoon Lanai
Date: Tuesday, December 13th
Time: 11:00 a.m. - 12:00 p.m.
Place: Lagoon Lanai
Date: Wednesday, December 14th
Time: 12:00 p.m. - 1:00 p.m.
Place: Lagoon Lanai
ACNP RECEPTION
Date: Thursday, December 15th
Time: 7:30 p.m. - 10:30 p.m.
Place: Monarchy Ballroom
SPECIAL EVENTS
Saturday, December 10, 2005
Travel Award Breakfast
(by invitation only)
Time: 6:00 p.m. - 7:30 p.m.
Place: Water’s Edge Ballroom
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Sunday, December 11, 2005
Travel Award Breakfast
Time: 7:00 a.m. - 8:00 a.m.
Past Presidents’ Luncheon
Time: 12:30 p.m. - 2:00 p.m.
Place: Water’s Edge Boardroom
Monday, December 12, 2005
Informal Networking Session for Spouses/Guests of Attendees
See flyer in registration tote bag
Time: 9:00 a.m. - 11:00 a.m.
Place: Kona 5
Media Training Session
Time: 7:30 p.m. - 10:00 p.m.
Place: Queen’s 6
Wednesday, December 14, 2005
Town Hall Meeting: Clinical Trials Registry & U.S. Drug Surveillance
System
Time: 7:00 a.m. - 8:00 a.m.
Place: Kona 4
Travel Award Luncheon
Time: 12:00 p.m. - 2:00 p.m.
Memorial Symposium
Time: 1:00 p.m. - 2:15 p.m.
Place: Queen’s 6
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Thursday, December 15, 2005
Teaching Neuropsychopharmacology
Time: 12:30 p.m. - 2:00 p.m.
Place: Kona 5
COLLEGE MEETINGS
Neuropsychopharmacology Editorial Board
Time: 11:30 a.m. - 12:45 p.m.
Place: Kona 4
Tuesday, December 13, 2005
Corporate Liaison Meeting
Time: 11:00 a.m. - 12:00 p.m.
Annual Business Meeting
(ACNP Scientific Members only)
Chair: Daniel Weinberger
Time: 10:45 a.m. - 11:45 a.m.
Place: Kona 4
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Council Meetings
Council is involved in many activities during the Annual Meeting. The official Council meetings are listed below:
ACNP Council
Time: 8:00 a.m. - 3:00 p.m.
2005 Committee Chairs - Reports to Council
Time: 6:00 p.m. - 11:00 p.m.
2006 Committee Chairs & ACNP Council
Time: 11:00 a.m. - 1:00 p.m.
COMMITTEE/TASK FORCE MEETINGS
Meetings listed below are as scheduled by the Committee Chairs. Committee
meetings, Task Force meetings, and activities not listed here will be posted at
the ACNP Registration Desk.
Credentials Committee
Time: 8:15 a.m. - 5:30 p.m.
Place: Kona 5
Animal Committee
Time: 10:00 a.m. – 12:00 p.m.
Place: Waikoloa 3
Constitution & Rules Committee
Time: 10:30 a.m. - 11:30 a.m.
Place: Waikoloa 2
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Saturday, December 10, 2005 (cont’d)
Ethics Committee
Time: 1:00 p.m. - 3:00 p.m.
Place: Queen’s 6
Medication Development Task Force
Time: 1:30 p.m. - 3:00 p.m.
Place: Queen’s 5
Advocacy Committee/Advocacy Affiliates/Coalition for
Mental Health Research
Time: 2:00 p.m. - 3:30 p.m.
Place: Kohala 2
Human Research Committee
Time: 2:00 p.m. - 4:00 p.m.
Place: Waikoloa 2
Liaison Committee
Time: 3:00 p.m. - 5:00 p.m.
Place: Kohala 1
Publications Committee
Time: 3:30 p.m. - 5:00 p.m.
Place: King’s 3
Finance Committee
Time: 3:30 p.m. - 5:30 p.m.
Place: King’s 2
Education & Training Committee
Time: 4:00 p.m. - 6:00 p.m.
Place: Kona 4
Public Information Committee
Time: 4:30 p.m. - 6:30 p.m.
Place: Queen’s 4
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2006 Nominating Committee
Time: 12:30 p.m. - 2:30 p.m.
Place: TBA
Program Committee
Time: 11:30 a.m. - 12:45 p.m.
The History Task Force will be video taping interviews by appointment in
Waikoloa 3.
ACNP SANCTIONED MEETINGS
(These Sanctioned Meetings are closed meetings.)
TURNS SOU Compound Selection Meeting
Date: Saturday, December 10, 2005
Time: 8:00 a.m. - 5:00 p.m.
NIDA Workshop
Time: 8:30 a.m. - 5:00 p.m.
Place: Kohala 3
CDI Booster Session
Time: 1:30 p.m. - 6:00 p.m.
Place: Kohala 4
Date: Sunday, December 11, 2005
Time: 12:30 p.m. - 2:30 p.m.
Place: Kohala 4
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SBP
Council
Time: 4:00 p.m. - 9:00 p.m.
Place: King’s 1
P rogram Committee
Date: Wednesday, December 14, 2005
Time: 11:45 a.m. - 1:30 p.m.
Place: Monarchy Ballroom (dancefloor area)
Emory-GSK-NIMH Steering Committee
Time: 12:30 p.m. - 2:30 p.m.
Place: Waikoloa 2
Duke Clinical Research Institute Private Function
Time: 8:00 p.m. - 10:00 p.m.
Place: Waikoloa 2
Date: Monday, December 12, 2005
Time: 9:00 p.m. - 11:00 p.m.
Place: Waikoloa 2
Time: 7:00 p.m. - 11:00 p.m.
Academic Consortium Meeting
Time: 12:00 p.m. - 1:15 p.m.
Place: Waikoloa 2
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In Memoriam
Ernest Sigg
October 12, 2004
Julius Axelrod
December 29, 2004
Peter Stokes
January 22, 2005
C. Jelleff Carr
February 15, 2005
David Segal
August 23, 2005
Mogens Schou
September 29, 2005
Frederic Quikin
October 9, 2005
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ACNP
44th
Annual Meeting
Scientific Program
Legends for tabs
PA-Panel
PL-Plenary Session
SG-Study Group
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8:00 AM - 12:30 PM
Teaching Day
Monarchy Ballroom
Teaching Day
Su
PL
Total Glia
Chair:
Kenneth L. Davis
8:00 a.m.
Welcome and Introduction
Kenneth L. Davis
8:10 a.m.
Glial Cells of Mammalian CNS
James E. Goldman
8:50 a.m.
Neuron-Glia Metabolic Coupling and its Relevance for
Functional Brain Imaging in Neuropsychiatry
Pierre J. Magistretti
9:30 a.m.
Oligodendrocytes and Myelination
Bruce D. Trapp
10:10 a.m.
Break
10:30 a.m.
Involvement of Glial Cells in the Pathophysiology and
Treatment of Severe Mood Disorders
Husseini K. Manji
11:10 a.m.
White Matter Abnormalities in Schizophrenia
Joseph D. Buxbaum
11:50 a.m.
Derivation of High Purity Neural Lineages from
Human Embryonic Stem Cells
Hans Keirstead
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2:30 - 5:00 PM
Hot Topics - Basic
Kona 5
Su
Hot Topics
PL
Basic/Translational
Chair:
Larry Siever
2:30 p.m.
Distinct Roles for Different Homer1 Isoforms in
Behaviors Associated with Prefrontal Cortex Function
in vivo
Karen Szumlinski
2:45 p.m.
Early-Onset Behavioral and Synaptic Deficits in a
Mouse Model of Alzheimer’s Disease Are Reversed by
Inhibition of Gamma Secretase
Menelas Pangalos
3:00 p.m.
Insulin And Igf-1 Reverse Mitochondrial, Energy
Metabolism, Proteasome, And Neuronal Plasticity
Gene Decreases Of Schizophrenia In An Mrna-Based
Screen For Antischizophrenia Agents
C. Altar
3:15 p.m.
Casein Kinase 1 Epsilon Modulates Sensitivity to
Stimulant Drugs in Both Mice and Humans: A
Translational Genetic Study
Abraham Palmer
3:30 p.m.
Histone Hyper-Acetylation Enhances Memory Storage
and Facilitates Synaptic Plasticity via the Transcription
Factor CREB
Ted Abel
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2:30 - 5:00 PM
Hot Topics - Basic
Kona 5
Hot Topics
Su
PL
Basic/Translational
Chair:
Larry Siever
3:45 p.m.
Neural Correlates of Anxiety in Serotonin 1A
Receptor-Deficient Mice
Joshua Gordon
4:00 p.m.
MUTED (6p24.3), a Protein That Binds to Dysbindin
(DTNBP1, 6p22.3), Is Strongly Associated with
Schizophrenia and Exhibits Statistical Epistasis with
COMT
Richard Straub
4:15 p.m.
Electroconvulsive Seizures Increase Cell Proliferation
in the Adult Monkey Cortex
Tarique Perera
4:30 p.m.
COMT Inhibition Enhances Neuregulin-Induced Cell
Migration in B Lymphoblasts
Elizabeth Tunbridge
4:45 p.m.
Engraftment of a Monoaminergic Cell Line within
Affective Neural Circuitry
Miles Cunningham
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2:30 - 5:00 PM
Hot Topics - Clinical
Kona 4
Su
Hot Topics
PL
Clinical
Chair:
Trey Sunderland
2:30 p.m.
Schizophrenia is Associated with Increased Synaptic
Dopamine in Associative Rather than Limbic Regions
of the Striatum
Marc Laruelle
2:45 p.m.
Early Postnatal Brain Structure and Development in
Humans: Sexual Dimorphism and Cerebral
Asymmetry are Present at Birth
John Gilmore
3:00 p.m.
Oxytocin Increases Social Cognition in Autism
Eric Hollander
3:15 p.m.
Influence of Low and High Dose Hydrocortisone
Infusion on Hemodynamic Response in Amygdala
While Viewing Emotional Faces
Kristine Erickson
3:30 p.m.
Distribution of [11C]PIB in a Nondemented
Population: Implication for Use as an Antecedent
Marker of Alzheimer’s Disease
Mark Mintun
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2:30 - 5:00 PM
Hot Topics - Clinical
Kona 4
Hot Topics
Su
PL
Clinical
Chair:
Trey Sunderland
3:45 p.m.
Glutamate Transporter Gene (SLC1A1) Associated
with Obsessive Compulsive Disorder
Paul Arnold
4:00 p.m.
Frontal Dopamine D2 Receptor Binding in
Neuroleptic-Naive First-Episode Schizophrenic
Patients Correlates with Positive Psychotic Symptoms
and Predicts Treatment Outcome
Birte Glenthoj
4:15 p.m.
The Trajectory is The Story: Cortical Gray Matter
Changes During Adolescence In Childhood Onset
Schizophrenia Evolve Into The Adult Pattern By
Age 25
Nitin Gogtay
4:30 p.m.
Corollary Discharge Failure in Schizophrenia is
Related to Severity of Auditory Hallucinations: fMRI
Evidence
Judith Ford
4:45 p.m.
Robust, Rapid and Relatively Sustained Antidepressant
Effects with a Single-Dose of an NMDA Antagonist in
Treatment-Resistant Major Depression: A DoubleBlind Placebo-Controlled Study
Carlos Zarate
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7:00 - 8:00 PM
Oakley Ray History Lecture
Kona 4
Su
PL
Fifty Years After Miltown: Tranquilizers,
History, and Psychiatry
Chair:
Carl Salzman
Presented by
Andrea Tone
Canada Research Chair in the Social History of Medicine
Social Studies of Medicine & Department of History
McGill University
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8:00 - 11:30 AM
President’s Plenary
Monarchy Ballroom
President's Plenary
Welcoming Remarks and Moment of Silence
Daniel Weinberger
President
Mo
PL
Presentation of Honorific Awards and Media Award
Carol Tamminga
Chair, Honorific Awards Committee
The Complexity of Complex Genetics: Beyond
Genes and Environment
Chair:
Daniel Weinberger
8:30 a.m.
Lessons from Mendelian Genetics About the Mistakes
Not to Make
Michael Dean
9:15 a.m.
Genetics of Addictions: From Behavior to Genetic
Architecture, and Back
David Goldman
10:00 a.m.
Imaging Genetics: Mapping the Mechanisms from
Genes to Circuits to Behavior
Andreas Meyer-Lindenberg
10:45 a.m.
The Long Term Neurobiological Consequences of
Stress in Early Life: Gene-Environment Interactions in
the Real World
Charles Nemeroff
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1:00 - 2:15 PM
Distinguished Lecture
Monarchy Ballroom
Mo
PL
Stem Cells Today and Stem Cells Tomorrow
Chair:
Daniel Weinberger
Presented by
Ronald D.G. McKay
Chief, Laboratory of Molecular Biology
National Institute of Neurological Disorders and Stroke
National Institutes of Health
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2:30 - 5:00 PM
Dopamine Beta Hydroxylase & Substance Abuse
King’s 2
Dopamine Beta Hydroxylase Genetics and Substance Abuse:
Of Mice and Men
Chair:
Co-Chair:
2:30 p.m.
Joseph Cubells
Thomas Kosten
Human Genetics of Plasma DBH Activity in Cocaine
Dependence
Joseph Cubells
Mo
PA
3:00 p.m.
Dopamine Beta-Hydroxylase Knockout Mice Have
Alterations in Dopamine Signaling and Are
Hypersensitive to Cocaine Locomotion, Reward, and
Aversion
David Weinshenker
3:30 p.m.
DBH Genotype and Human Self-Administration of
Cocaine
Robert Malison
4:00 p.m.
Norepinephrine in Opiate Reward, Locomotion, and
Withdrawal: Evidence for Distinct Contributions by the
Locus Coeruleus and the Nucleus Tractus Solitarius
Valerie Olson
4:30 p.m.
Discussion
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2:30 - 5:00 PM
Cortical GABAergic Systems in Schizophrenia
Kona 4
Specificity of Cortical GABAergic Systems:
Development and Disturbances in Schizophrenia
Chair:
Co-Chair:
David Lewis
John Krystal
2:30 p.m.
Fate Determination of Cortical Interneurons. It Is Who
You Are, Not How You Get There
Stewart Anderson
3:00 p.m.
Regulation of Axon Growth and Inhibitory Synapses
Formation by GAD67-Mediated GABA Signaling:
Implications in Schizophrenia Pathogenesis
Z. Josh Huang
3:30 p.m.
Differential Vulnerability of Specific Cortical GABA
Systems in Schizophrenia
David Lewis
4:00 p.m.
New Clinical Evidence Implicating GABA Systems in
Psychosis and Cognition: Implications for
Schizophrenia
John Krystal
4:30 p.m.
Discussion
Mo
PA
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2:30 - 5:00 PM
G Protein-Coupled Receptors
King’s 1
Homo- and Hetero-Dimerization of G Protein-Coupled
Receptors: Drug Mechanisms and Pharmacological Diversity
Chair:
2:30 p.m.
3:00 p.m.
Jonathan Javitch
Functional and Pharmacological Consequences of
Oligomeric Assemblies in G-Protein-Coupled Receptor
Signalling
Mo
Michel Bouvier
PA
Hetero-Dimerization of CNS Expressed G ProteinCoupled Receptors: Implications for Drug Function
Graeme Milligan
3:30 p.m.
Role of GPCR Oligomerization in Regulating
Receptors by Endocytic Membrane Trafficking
Mark von Zastrow
4:00 p.m.
Crosstalk in G Protein-Coupled Receptors: Changes at
the Transmembrane Homodimer Interface Determine
Activation
Jonathan Javitch
4:30 p.m.
Discussion
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Successful Aging
King’s 3
Successful Aging: A Neuropsychiatric Entity
Chair:
Co-Chair:
2:30 p.m.
Mo
Dilip Jeste
Trey Sunderland
A Psycho-Bio-Social Study of Successful Aging
Among Community-Dwelling Seniors
Dilip Jeste
PA 3:00 p.m.
Genome Survey for Loci that Influence Successful
Aging
George Zubenko
3:30 p.m.
Neurodegeneration and Regeneration in the Aging
Nervous System
Laura Dugan
4:00 p.m.
Effects of a 14-Day Healthy Aging Lifestyle Program
on Brain Function
Gary Small
4:30 p.m.
Discussion
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2:30 - 5:00 PM
Translational Measures of Depression
Kona 5
Towards Building Translational Measures of Depression:
Objective Characterizations of Depressive Phenotypes
and Biomarkers in Humans and Animals
Chair:
Co-Chair:
2:30 p.m.
Athina Markou
Diego Pizzagalli
Objective Measures of Core Cognitive Symptoms of
Depression
Barbara Sahakian
3:00 p.m.
Laboratory Measures of Anhedonia in Humans: A
Signal Detection Approach
Diego Pizzagalli
3:30 p.m.
Measuring Anhedonia in Animals: Reversal by
Antidepressant Treatments
Athina Markou
4:00 p.m.
Long-Term Neurobehavioural Effects of Early Life
Adversity in Rats and Monkeys with Relevance to
Depression
Joram Feldon
4:30 p.m.
Discussion
35
Mo
PA
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2:30 - 5:00 PM
Immune Mediators on Brain Circuits
Queen’s 4
Effects of Immune Mediators on the Development of
Brain Circuits Regulating Cognition and Emotion
Chair:
Co-Chair:
Lois Winsky
Mark Geyer
2:30 p.m.
The Effects of Prenatal Infection on Mechanisms
Critical for Cortical Development
John Gilmore
3:00 p.m.
Sensorimotor Gating Deficits in Rodent
Developmental Models Related to Psychotic Disorders
Mark Geyer
3:30 p.m.
The Impact of Infection Early in Life on the Formation
of Long-Term Memories in Adulthood
Steven Maier
4:00 p.m.
Maternal Influenza Infection Leads to Neuropathology
and Behavioral Abnormalities in Adult Offspring
Paul Patterson
4:30 p.m.
Discussion
Mo
PA
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2:30 - 5:00 PM
Genes and Brain Development
Queen’s 6
Genes and Brain Development in Health and Illness:
The Trajectory is the Story
Chair:
Co-Chair:
2:30 p.m.
Jay Giedd
Judith Rapoport
The Genetics of Cerebral Cortex Development in the
Mouse
Susan McConnell
Mo
PA
3:00 p.m.
Searching for the Cause of Dyslexia: To Gel and Bac
Albert Galaburda
3:30 p.m.
Trajectories of Anatomic Brain Development in
Children and Adolescents
Jay Giedd
4:00 p.m.
Genes, Brain Development and Clinical Outcome in
Children with Attention Deficit/Hyperactivity Disorder
(ADHD)
Philip Shaw
4:30 p.m.
Discussion
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2:30 - 5:00 PM
Phase IV Studies & Off-Label Prescribing
Queen’s 5
The Future of Phase IV Studies and Off-Label Prescribing:
The Conundrum Facing Corporate Sponsors of Research,
Regulators, Clinical Investigators and the
Future of Psychiatric Practice
Chair:
Co-Chair:
2:30 p.m.
Mo
PA 3:00 p.m.
Roger Meyer
Alexander Glassman
Dealing with the Challenging Legal Environment for
Phase IV Clinical Trials and Off-Label Prescribing
Sandra Johnson
The Changing Legal Environment Around Phase IV
Studies: The Industry Response
Dave Ceryak & Doug Snyder
3:30 p.m.
Reporting of Phase 4 Studies in Scholarly Journals
Richard Glass
4:00 p.m.
The Future of Phase IV Studies and Off-Label
Prescribing: The Conundrum Facing Corporate
Sponsors of Research, Regulators, Clinical
Investigators and the Future of Psychiatric Practice
David Meltzer
4:30 p.m.
Discussion/Response Panel:
Paul Andreason, Donald Klein, Charles O’Brien
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Development of Radiotracers as Useful Biomarkers
Queen’s 4
Developing a Consortium and Mechanism to Facilitate the
Development of Radiotracers as Useful Biomarkers
in Academia and Industry
Chair:
Dean F. Wong
Co-Chairs:
Linda Brady
Robert Innis
Participants: Donald Burns
Lars Farde
Colin Fish
Richard Frank
Paul Gaylo
Hartmuth Kolb
Timothy McCarthy
Steven Paul
William Potter
Mark Schmidt
Jill Sorensen
39
Mo
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J’Accuse: COI in the News, but What of the Accused?
Queen’s 5
J’Accuse: COI in the News, but What of the Accused?
Chair:
Mo
Participants: Alan Breier
William Carpenter
Ezekiel Emanuel
Jack Gorman
Robert Muse
Jamie Talan
Daniel Weinberger
SG
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8:00 - 10:30 AM
Animal Models of Schizophrenia
Kona 4
Animal Models of Schizophrenia:
Making Progress or Just a Delusion?
Chair:
Co-Chair:
8:00 a.m.
8:30 a.m.
Barbara Lipska
Shitij Kapur
Morphological and Molecular Changes in the
Prefrontal Cortex of Rats Following Neonatal Ventral
Hippocampus Damage
Lalit Srivastava
Genetic Animal Models of Psychosis: The
Dopamine/Glutamate Interaction
Marc Caron
9:00 a.m.
New Genetic Mouse Models of Schizophrenia:
Mimicking Cognitive Dysfunction by Altering
Susceptibility Gene Expression
Jingshan Chen
9:30 a.m.
Modelling Antipsychotic Action - Convergence from
Studies of Mice and Men
Shitij Kapur
10:00 a.m.
Discussion
41
Tu
PA
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8:00 - 10:30 AM
Noradrenergic & Dopaminergic of Cognition
Kona 5
Noradrenergic and Dopaminergic Modulation
of Prefrontal Cognition
Chair:
Co-Chair:
Larry Siever
Daniel Weinberger
8:00 a.m.
Amygdala Modulation of Conditioning within the
Prefrontal Cortex is Dependent on Cannabinoid and
Dopamine D4 Receptor Activation
Anthony Grace
8:30 a.m.
Relative Roles for Dopamine and Norepinephrine in
Attentional Function and the Behavioral Effects of
Methylphenidate and Other Therapeutic Agents for
ADHD
Trevor Robbins
9:00 a.m.
Noradrenergic and Dopaminergic Interventions in the
Schizophrenia
Larry Siever
9:30 a.m.
COMT in Prefrontal Cortex and Beyond: Genetic
Studies of Cortical DA Signaling
Daniel Weinberger
10:00 a.m.
Discussion
Tu
PA
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Steroid Hormones & Addiction
King’s 2
Steroid Hormones and Addiction: From Genes to Behavior
Chair:
Co-Chair:
Daniel Dorsa
Jill Becker
8:00 a.m.
Effects of Estrogen in the Brain: Roles of ER Alpha
and Beta in Neurons and Glia
Daniel Dorsa
8:30 a.m.
Sex Differences and Influences of Steroid Hormones
in Drug Abuse
Jill Becker
Tu
PA
9:00 a.m.
Steroid Hormones, DARPP-32 and Signal Integration
Mechanisms in Brain and Behavior
Shaila Mani
9:30 a.m.
Anabolic Steroid Addiction? Insights from Animal
Studies
Ruth Wood
10:00 a.m.
Discussion
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8:00 - 10:30 AM
Biomarkers in Alzheimer’s Disease
King’s 3
Drug Development
Biomarkers in Alzheimer’s Disease:
Early Diagnostic and Treatment Implications
Chair:
Co-Chair:
Trey Sunderland
George Zubenko
8:00 a.m.
D10S1423 Identifies Susceptibility Locus AD7 for
Alzheimer’s Disease in a Prospective, Longitudinal,
Double-Blind Study of Asymptomatic Individuals
George Zubenko
8:30 a.m.
Cerebrospinal Fluid Peptides as Biomarkers for
Presymptomatic AD in “At Risk” Controls
Trey Sunderland
9:00 a.m.
Antecedent Biomarkers for Alzheimer’s Disease
John Morris
9:30 a.m.
CSF Biomarkers Add to Delayed Recall and
Hippocampal Volume in Diagnosing MCI
Mony de Leon
10:00 a.m.
Discussion
Tu
PA
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8:00 - 10:30 AM
Prefrontal Cortex & Cognitive Flexibility
King’s 1
The Prefrontal Cortex and Cognitive Flexibility
Chair:
Co-Chair:
Daniel Pine
Ellen Leibenluft
8:00 a.m.
Reversal Learning in Primates: A Neuroanatomical,
Neurochemical and Behavioral Analysis
Angela Roberts
8:30 a.m.
The Primate Prefrontal Cortex and the Executive
Control of Attention
Leslie Ungerleider
9:00 a.m.
The Prefrontal Cortex and Cognitive Flexibility
Cameron Carter
9:30 a.m.
Response Flexibility in Bipolar Disorder: A
Developmental Perspective
Ellen Leibenluft
10:00 a.m.
Discussion
45
Tu
PA
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Stress, Pain and Emotions
Queen’s 5
Stress, Pain and Emotions
Chair:
Co-Chair:
Charles Nemeroff
Emeran Mayer
8:00 a.m.
Brain Systems Regulating the Organism’s Response to
Stress: Preclinical and Clinical Studies
Charles Nemeroff
8:30 a.m.
Chronic Pain and Depression
Alan Schatzberg
9:00 a.m.
Irritable Bowel Syndrome: Brain Mechanisms Involved
in the Generation of Chronic Visceral Pain and How
Emotions and Cognitions Can Alter Normal Processing
of Visceral Stimuli
Emeran Mayer
9:30 a.m.
Fibromyalgia: Brain Mechanisms Involved in the
Generation of Chronic Somatic Pain and How Somatic
Pain Processing is Altered in the Setting of Altered
Mood and Cognitions
Daniel Clauw
10:00 a.m.
Discussion
Tu
PA
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8:00 - 10:30 AM
Neuroimaging Findings & Panic Disorder
Queen’s 4
New Neuroimaging Findings in the Pathophysiology
and Treatment of Panic Disorder
Chair:
Co-Chair:
Scott Rauch
Jack Gorman
8:00 a.m.
Functional Magnetic Resonance Imaging Studies of
Amygdalo-Cortical Function in Panic Disorder
Scott Rauch
8:30 a.m.
Functional Magnetic Resonance Imaging of Attention
and Emotion Recognition in Panic Disorder
Srinivasan Pillay
9:00 a.m.
fMRI Studies of Fronto-Limbic Fear Circuitry in Panic
Tu
Disorder
David Silbersweig
PA
Regional Metabolic Brain Activation in Patients with
Panic Disorder During Doxapram Infusion
Jack Gorman
9:30 a.m.
10:00 a.m.
Discussion
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Bipolar Disorders: European Contributions
Queen’s 6
ECNP Panel
Bipolar Disorders: European Contributions
Chair:
Co-Chair:
David Nutt
Guy Goodwin
8:00 a.m.
Exploring the Endophenotype in Bipolar Disorder
Guy Goodwin
8:30 a.m.
Diagnosis of Bipolar Disorder in Children and Adults
(A European Perspective)
Jan Buitelaar
9:00 a.m.
A Critical Analysis of the Value of Psychoeducation in
Bipolar Disorder
Eduard Vieta
Tu
PA 9:30 a.m.
10:00 a.m.
The Treatment of Depression in Bipolar Disorder (An
European Perspective)
Heinz Grunze
Discussion
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12:00 - 2:30 PM
Issues in Ethics
Monarchy Ballroom
Issues in Ethics
Rethinking Risk in Clinical Research
Chair:
Co-Chair:
David Rubinow
David Braff
Donald Rosenstein
Acting Clinical Director
National Institute of Mental Health
Jane Pearson
Acting Deputy Director
Division of Services and Intervention Research
Lydia Lewis
President
The Depression and Bipolar Support Alliance
James Harris
Director, Developmental Neuropsychiatry
Johns Hopkins University School of Medicine
David Brent
Academic Chief
Child and Adolescent Psychiatry
Western Psychiatric Institute and Clinic
Paul Andreason
Acting Deputy Director
Division of Psychiatric Products
Food and Drug Administration
49
Tu
PL
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Lipid Rafts, Caveolae & Signal Transduction
King’s 3
Lipid Rafts, Caveolin-Related Proteins and Neuronal Signaling
Chair:
Co-Chair:
Bryan Roth
Mark Rasenick
2:30 p.m.
Caveolin: A Novel Regulator of GPCR Signaling
Bryan Roth
3:00 p.m.
Caveolin-1 Interacts with Metabotropic Glutamate
Receptors and Participates in Receptor Trafficking
Anna Francesconi
3:30 p.m.
Agonist-Induced Lipid Raft Trafficking and
Subsequent Internalization of G alpha s Regulates
cAMP Signaling
Mark Rasenick
Tu
PA 4:00 p.m.
4:30 p.m.
Lipid Rafts and Neural Cell Adhesion Molecules in
Axon Growth
Vance Lemmon
Discussion
50
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2:30 - 5:00 PM
Molecular Mechanisms of Drug Dependence
Queen’s 4
JSNP Panel
Molecular Mechanisms of Drug Dependence Induced
by Amphetamine and Related Drugs
Chair:
Co-Chair:
Toshitaka Nabeshima
Edward Domino
2:30 p.m.
Overview
2:35 p.m.
Candidate Gene Analysis of MethamphetamineRelated Disorders
Hiroshi Ujike
3:00 p.m.
Brain Imaging Reveals Corticolimbic Dysregulation in
Methamphetamine Abusers
Tu
Edythe London
3:25 p.m.
Mesolimbic Dopamine D2/D3 Receptor-Mediated
Signaling in Methamphetamine-Sensitized Rats
Jin-Chung Chen
3:50 p.m.
The Role of Tissue Plasminogen Activator in
Methamphetamine-Related Reward and Sensitization
Kiyofumi Yamada
4:15 p.m.
Serotonin Modulation of the Effects of Amphetamine
and Phencyclidine: Locomotor Hyperactivity and
Prepulse Inhibition Studies in Rats
Maarten van den Buuse
4:40 p.m.
Question and Answer
51
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2:30 - 5:00 PM
Dopamine & Computational Modeling
King’s 1
What Does Dopamine Say: Clues from Computational Modeling
Chair:
Co-Chair:
Tu
Steven Grant
Jonathan Cohen
2:30 p.m.
The Role of Dopamine in the Temporal Difference
Model of Reinforcement Learning
Read Montague
3:00 p.m.
Dopamine Encodes a Quantiative Reward Prediction
Error for Reinforcement Learning
Paul Glimcher
3:30 p.m.
Implications of the Temporal Difference
Reinforcement Learning Model for Addiction and
Relapse
A. David Redish
4:00 p.m.
Dopamine-Norepinephrine Interactions: Exploitation
versus Exploration
Jonathan Cohen
4:30 p.m.
Discussion
PA
52
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2:30 - 5:00 PM
Feeding Neuropeptides & Drug Dependence
Queen’s 6
The Role of Feeding Neuropeptides in Alcohol
and Drug Dependence
Chair:
Co-Chair:
Michael Lewis
George Koob
2:30 p.m.
Galanin and Opioid Peptides in Relation to Alcohol
Intake and Dietary Fat: Possible Positive Feedback
Mechanisms
Sarah Leibowitz
3:00 p.m.
Neuropeptide Y and Melanocortin Neuropeptides
Regulate Alcohol Intake and Feeding: Are Overlapping
Pathways Involved?
Todd Thiele
3:30 p.m.
Not Your Mother’s CRF: Type 2 Urocortins, Selective
CRF2 Receptor Agonists, Reduce Excessive Ethanol
Drinking and Overeating
George Koob
4:00 p.m.
Sugar Bingeing Produces Effects on Opioid and
Dopamine Systems: Possible Roles in Drug Abuse
Bartley Hoebel
4:30 p.m.
Discussion
53
Tu
PA
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2:30 - 5:00 PM
Novel Metabotropic Glutamate Receptor Agents
Kona 5
Drug Development
Development of Novel Metabotropic Glutamate Receptor
Agents for the Treatment of Schizophrenia and
Anxiety-Related Disorders
Chair:
Co-Chair:
Athina Markou
Anne Lesage
2:30 p.m.
Positive Allosteric Modulators of Metabotropic
Glutamate Receptor 5: A New Generation of
Antipsychotics?
Vincent Mutel
3:00 p.m.
Description of a Clinically Validated Anxiolytic with
mGlu5 Antagonist Properties
Richard Porter
Tu
PA 3:30 p.m.
Anxiolytic and Cognitive Properties of the mGlu1
Receptor Negative Allosteric Modulator JNJ16259685
Anne Lesage
4:00 p.m.
mGluR7: A Novel Therapeutic Target for StressRelated Disorders
John F. Cryan
4:30 p.m.
Discussion
54
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2:30 - 5:00 PM
Practical Clinical Trials of Antipsychotic Drugs
Kona 4
Drug Development
Practical Clinical Trials of Antipsychotic Drugs in Schizophrenia
Chair:
Co-Chair:
Jeffrey Lieberman
Susan Essock
2:30 p.m.
First Generation versus Second Generation
(non-clozapine) Antipsychotic Drugs versus Clozapine
in Schizophrenia: The CUtLASS Trials
Shon Lewis
3:00 p.m.
Effectiveness of Antipsychotic Drugs in Patients with
Chronic Schizophrenia: Primary Efficacy and Safety
Outcomes of the Clinical Antipsychotic Trials of
Intervention Effectiveness (CATIE) Schizophrenia
Tu
Trial
Jeffrey Lieberman
PA
3:30 p.m.
Effectiveness of Antipsychotic Drugs in Unresponsive
and Intolerant Patients
Joseph McEvoy
4:00 p.m.
Cost-Effectiveness of Atypical Antipsychotics in the
CATIE Schizophrenia Trial
Robert Rosenheck
4:30 p.m.
Discussion
55
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2:30 - 5:00 PM
Corticolimbic Changes in Bipolar Disorder
King’s 2
Corticolimbic Changes in Bipolar Disorder:
A Developmental Perspective
Chair:
Co-Chair:
Tu
Caleb Adler
Stephen Strakowski
2:30 p.m.
Prefrontal-Amygdalar Abnormalities in Pediatric
Bipolar Disorder
Kiki Chang
3:00 p.m.
Progression of Anterior Limbic Dysfunction in
Adolescent Bipolar Disorder
Melissa DelBello
3:30 p.m.
Multimodality Magnetic Resonance Imaging Evidence
for Abnormalities in Cortico-limbic Structural and
Functional Connectivity in Bipolar Disorder
Hilary Blumberg
4:00 p.m.
Complementary Morphometric and Functional
Corticolimbic Changes in Adult Bipolar Patients
Caleb Adler
4:30 p.m.
Discussion
PA
56
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2:30 - 5:00 PM
Drug Addiction: Novel Pharmacological Approaches
Queen’s 5
Novel Pharmacological Approaches to the Treatment of Drug
Addiction: Animal and Human Studies
Chair:
Co-Chair:
Charles O’Brien
Laura Peoples
2:30 p.m.
The Differential Neuroplasticity and Differential
Inhibition Hypotheses of Drug Addiction: Empirical
Evidence and Implications for Treatment
Laura Peoples
3:00 p.m.
Novel Pharmacological Targets for Relapse Prevention:
Animal Studies
Friedbert Weiss
3:30 p.m.
Regulating Glutamate Homeostasis in Treating
Cocaine Addiction
Peter Kalivas
4:00 p.m.
Translating Data from Animal Models to New
Treatments for Addiction
Charles O’Brien
4:30 p.m.
Discussion
57
Tu
PA
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8:00 - 10:30 AM
The Warrior/Worrier Paradox
King’s 1
The Warrior/Worrier Paradox: Varying Allelic Effects and
Counter Balancing Selection of Phenotypes
Chair:
Co-Chair:
8:00 a.m.
The 5HTTLPR Low Versus High Activity Alleles are
Associated with High Versus Low Aggressive
Behaviour, But Not Suicidality
James Kennedy
8:30 a.m.
CNS Serotonergic Functioning, Alcohol, Genotype X
by Rearing Interactions and Violence Using a
Nonhuman Primate Model
James Higley
9:00 a.m.
Variation in Allelic Expression of Genes Associated
with Aggression
Larry Siever
9:30 a.m.
Novel Functional Variation in the Serotonin
Transporter and Tryptophan Hydroxylase Genes and
Linkage to Complex Behavioral Phenotypes
David Goldman
10:00 a.m.
Discussion
We
PA
Larry Siever
David Goldman
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Subregions Medial Temporal Lobe & Cognition
King’s 2
Subregions in the Medial Temporal Lobe:
Implications for Normal and Disordered Cognition
Chair:
Co-Chair:
Terry Goldberg
Stephan Heckers
8:00 a.m.
The Hippocampus and Episodic Memory: Cognitive
and Neural Mechanisms
Howard Eichenbaum
8:30 a.m.
Binding Processes and Structures in Working Memory
and Long-Term Memory: Interaction of Hippocampal
and Neocortical Areas
Jaap Murre
9:00 a.m.
Hippocampal Contribution to the Novel Use of
Relational Information in Declarative Memory
John Gabrieli
9:30 a.m.
Hippocampal Dysfunction in Psychiatric Disorders
Stephan Heckers
10:00 a.m.
Discussion
59
We
PA
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8:00 - 10:30 AM
GSK-3: A Novel Target for Severe Neuropsychiatric Diseases
Kona 5
Drug Development
GSK-3: A Novel Target for Improved Therapeutics
for Severe Neuropsychiatric Diseases
Chair:
Co-Chair:
We
Marc Caron
Husseini Manji
8:00 a.m.
Involvement of an Akt/β-arrrestin2/PP2A Signaling
Complex in the Actions of Dopamine
Marc Caron
8:30 a.m.
Targeting Glycogen Synthase Kinase-3 as a Treatment
for Bipolar Disorder
Todd Gould
9:00 a.m.
GSK-3 as a Target of Lithium Action in Bipolar
Disorder and Alzheimer’s Disease
Peter Klein
9:30 a.m.
Genetic Analysis of GSK-3·α and β in Conditional
Knockout Mice and Stem Cells
Jim Woodgett
10:00 a.m.
Discussion
PA
60
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Screening Models for Alcoholism Medications
King’s 3
Validation of Screening Models for Medications
Development to Alcoholism
Chair:
Co-Chair:
Robert Swift
Raye Litten
8:00 a.m.
High Throughput Pharmacological Screening for Lead
Compounds at Molecular Targets of Relevance to
Alcohol Dependence
John Littleton
8:30 a.m.
Development of Animal Models of Excessive
Drinking, Protracted Abstinence, and Cue-Induced
Relapse for Medications Development
George Koob
9:00 a.m.
Application of Functional Genomics to Animal Models
of Alcoholism for Target Discovery and Validation
Markus Heilig
9:30 a.m.
Development and Validation of Human Laboratory
Models for the Prediction of Medication Efficacy in
Clinical Trials
Barbara Mason
10:00 a.m.
Discussion
61
We
PA
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Treating the Elderly with Antipsychotics
Queen’s 4
Is it Worth the Risks? Treating the Elderly with Antipsychotics
Chair:
Co-Chair:
We
Lon Schneider
Pierre Tariot
8:00 a.m.
What Are the Risks?
Lon Schneider
8:30 a.m.
Long-Term Adverse Effects: Old and New?
Dilip Jeste
9:00 a.m.
What About Efficacy?
Pierre Tariot
9:30 a.m.
Cost-Effectiveness of Atypical Antipsychotics in the
CATIE Alzheimers Disease Trial
Robert Rosenheck
10:00 a.m.
Discussion
PA
62
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8:00 - 10:30 AM
Neuregulin and Schizophrenia
Queen’s 5
Neuregulin and Schizophrenia:
From Genetic Sequence to Pathogenic Mechanisms
Chair:
Daniel Weinberger
8:00 a.m.
The Relevance of NRG1-erbB Signaling in
Oligodendrocytes to Schizophrenia
Gabriel Corfas
8:30 a.m.
Neuregulin, Nicotine and Schizophrenia
David Talmage
9:00 a.m.
Neuregulin mRNA and Protein in Patients with
Schizophrenia
Cynthia Weickert
9:30 a.m.
SNPing Away at NRG1 and ErbB4 Gene Expression in
Schizophrenia
We
Amanda Law
10:00 a.m.
Discussion
PA
63
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8:00 - 10:30 AM
Sensorimotor Gating: A New Role for the CRF System
Queen’s 6
Animal Models of Deficient Sensorimotor Gating:
A New Role for the Corticotropin-Releasing Factor System?
Chair:
Co-Chair:
\We
Mark Geyer
Vaishali Bakshi
8:00 a.m.
CRF1 and CRF2 Receptor Modulation of Information
Processing
Victoria Risbrough
8:30 a.m.
Is Dopamine to Blame for CRF-Induced Sensorimotor
Gating Deficits in Rats?
Ronald Hammer
9:00 a.m.
Effects of Antipsychotics and Manipulations of the
Serotonin System on the Corticotropin-Releasing
Factor-Induced Decrease in PPI in Rats
Lisa Conti
9:30 a.m.
Acute and Long-Term Effects of Stress and CRF on
Prepulse Inhibition
Vaishali Bakshi
10:00 a.m.
Discussion
PA
64
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2:30 - 5:00 PM
Synaptic Alterations in Neuropsychiatric Disorders & Addiction
King’s 1
Molecular Mechanisms of Synaptic Alterations Associated
with Neuropsychiatric Disorders and Addiction
Chair:
Co-Chair:
Lorna Role
Jonathan Pollock
2:30 p.m.
Synapse Assembly in the Developing Brain: The
Active Role of the Adhesion Molecule SynCAM
Thomas Biederer
3:00 p.m.
Identification and Analysis of a Rac1 Regulator That
Mediates Dendritic Pruning
Peter Scheiffele
3:30 p.m.
Developmental Synapse Elimination is Mediated by
the Complement Cascade
Ben Barres
4:00 p.m.
Synapse to Nucleus Signaling During Long-term
Synaptic Plasticity: A Role for the Classical Active
Nuclear Import
Kelsey Martin
4:30 p.m.
Discussion
65
We
PA
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2:30 - 5:00 PM
Tourette Syndrome: Neuropsychiatric Disorders
King’s 3
Tourette Syndrome-A Window into Neurochemistry
and Neuropharmacology of Many
Comorbid Neuropsychiatric Disorders
Chair:
Co-Chair:
We
Dean Wong
Anthony Grace
2:30 p.m.
Striatal Biology and Tourette Syndrome
Roger Albin
3:00 p.m.
Tics and Tourette Syndrome in Children: Genetics and
Public Health Impact
Lawrence Scahill
3:30 p.m.
Abnormalities of the Dopamine and Serotonin Systems
Associated with Tourette Syndrome
Dean Wong
4:00 p.m.
Treatment of Tourette Syndrome and Co-Occurring
Conditions
John Walkup
4:30 p.m.
Discussion
PA
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Advances in Neurotensin Neurobiology
Queen’s 4
Drug Development
Advances in Neurotensin Neurobiology: Implications for
Novel Treatments for Psychosis and Drug Abuse
Chair:
Co-Chair:
2:30 p.m.
Elliott Richelson
Charles Nemeroff
Viral Vector-Induced Overexpression of the NT1
Receptor in the Nucleus Accumbens: Further Evidence
for Antipsychotic Effects of Increased NTergic
Neurotransmission
Charles Nemeroff
3:00 p.m.
Neurotensin Regulation of Corticostriatal Function:
Implications for Schizophrenia
Ariel Deutch
3:30 p.m.
The Role of Neurotensin in Estrous Cycle Regulation
of Prepulse Inhibition of Acoustic Startle
We
Becky Kinkead
PA
NT69L: A Neurotensin Receptor Agonist for
Treatment of Neuropsychiatric Diseases
Elliott Richelson
4:00 p.m.
4:30 p.m.
Discussion
67
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Cortical Dopaminergic Neurotransmission & Cognition
Kona 5
Cortical Dopaminergic Neurotransmission and Cognition:
Neuroimaging and Physiologic Studies
Chair:
Co-Chair:
We
Robert Innis
Karen Berman
2:30 p.m.
Dopamine Modulation of Glutamate and GABA
Responses in the Rat Prefrontal Cortex
Patricio O’Donnell
3:00 p.m.
The Cortical D1 Receptor: A Biomarker for Cortical
Dopamine Transmission?
Anissa Abi-Dargham
3:30 p.m.
PET Imaging of Dopamine Metabolism and Receptors
in Cortex: Relation to Cognitive Function in
Parkinson’s Disease
Robert Innis
4:00 p.m.
Interactions of Prefrontal Function and Dopamine:
Multimodal Neuroimaging of Genetic Modulation
4:30 p.m.
Discussion
PA
68
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Protein Trafficking & Therapeutic Mechanisms
Queen’s 6
Protein Trafficking and Therapeutic Mechanisms
for Mood Disorders
Chair:
Co-Chair:
Mark Rasenick
Maurizio Popoli
2:30 p.m.
G Protein Trafficking and its Relevance to Depression
and Antidepressant Therapy
Mark Rasenick
3:00 p.m.
Regulation of G Protein-Coupled Receptors by
Endocytosis
Mark von Zastrow
3:30 p.m.
Modulation of AMPA Glutamate Receptor Trafficking
by Antimanic Agents New Avenues for Drug
Development
Jing Du
4:00 p.m.
Leveling Glutamate Release: A Presynaptic Path
Toward Antidepressant Action
Maurizio Popoli
4:30 p.m.
Discussion
69
We
PA
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5-HT6 Receptors & Neuropsychiatric Disorders
King’s 2
5-HT6 Receptors: New Targets for Neuropsychiatric Disorders
Chair:
Co-Chair:
2:30 p.m.
John Neumaier
Theresa Branchek
The 5-HT6 Receptor: Filled with Promise or Promises
Unfilled?
David Nelson
3:00 p.m.
5-HT6 Receptors in Striatum Inhibit RewardMotivated Learning
John Neumaier
3:30 p.m.
Selective Serotonin 5-HT6 Receptor Antagonist(s) for
the Treatment of Obesity
Patrizia Caldirola
We 4:00 p.m.
PA
4:30 p.m.
A 14 Day, Dose Escalation, Double Blind,
Randomized, Placebo-Controlled Study of SGS518 in
Adult Patients with Schizophrenia
Ann Neale
Discussion
70
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Stress in Addiction Relapse & Treatment Targets
Queen’s 5
Stress in Addiction Relapse: Are There Viable Treatment Targets?
Chair:
Co-Chair:
Charles O’Brien
Rajita Sinha
2:30 p.m.
Novel Pharmacological Treatment Targets to Address
Stress-Induced Relapse: Insights from Animal Models
Friedbert Weiss
3:00 p.m.
The Role of Stress in Smoking Relapse: That’s So
Yesterday
Saul Shiffman
3:30 p.m.
Lofexidine Attenuates Stress Induced Drug Craving
and Arousal to Improve Stress-Induced Relapse
Outcomes
Rajita Sinha
4:00 p.m.
Stress and Drug Cues Motivate Smoking Relapse: Are We
There Neurobiological Substrates That Account for
This Association?
PA
Raymond Niaura
4:30 p.m.
Discussion
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Animal Models to Predict Pro-Cognitive Effects
King’s 1
Selecting Animal Models to Predict Pro-Cognitive Effects in
Human Populations
Chair:
Co-Chair:
Th
John Csernansky
Mark Geyer
8:00 a.m.
Predictive Validity of Rodent Models of Learning and
Memory
John Csernansky
8:30 a.m.
Neuropsychopharmacological Models of Attentional
Dysfunction and Their Translation to the Clinic
Trevor Robbins
9:00 a.m.
Evaluating Sensorimotor Gating Measures in Animals
as Predictors of Pro-Cognitive Effects in Humans
Mark Geyer
9:30 a.m.
Serotonergic Neuromodulation of Behavioral and
Cognitive Functions in Humans
Franz Vollenweider
10:00 a.m.
Discussion
PA
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Synaptic Plasticity & Long-Term Depression
King’s 2
Synaptic Plasticity: Focus on the Mechanisms and Clinical
Implications of Long-Term Depression
Chair:
Co-Chair:
Robert Malenka
Mark Bear
8:00 a.m.
Regulation of AMPA Receptor Function and Synaptic
Plasticity
Richard Huganir
8:30 a.m.
Distinct Triggering and Expression Mechanisms
Underlie LTD of AMPA Receptor and NMDA
Receptor Synaptic Responses
Robert Malenka
9:00 a.m.
Long-Term Synaptic Plasticity at Excitatory and
Inhibitory Synapses on Dopamine Neurons of the VTA
Julie Kauer
9:30 a.m.
The mGluR Theory of Fragile X Mental Retardation
Mark Bear
10:00 a.m.
Discussion
73
Th
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Functional Neuroanatomy & Neurochemistry of Resilience
Kona 5
Advances in Functional Neuroanatomy and
Neurochemistry of Resilience
Chair:
Co-Chair:
Rachel Yehuda
Dennis Charney
8:00 a.m.
Neural Substrates of Stress Inoculation Determined in
vivo by Brain Imaging in Monkeys
David Lyons
8:30 a.m.
Neuroanatomic and Neuroendocrine Alterations in
Trauma Survivors Associated with Coping and PTSD
Risk Factors
Rachel Yehuda
9:00 a.m.
Levels of Emotional Awareness and Alexithymia in
Traumatized Subjects with and Without PTSD:
Implications for Resilience
Ruth Lanius
9:30 a.m.
Th
The Psychobiology of Human Resilience to Stress
Dennis Charney
PA 10:00 a.m.
Discussion
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Emotion Recognition & Schizophrenia
King’s 3
If You Prick Them, Do They not Bleed?
Emotion Recognition and Schizophrenia
Chair:
Co-Chair:
Daniel Javitt
Pamela Butler
8:00 a.m.
Hear No Evil: Early-Stage Auditory Processing and
Emotion Recognition Deficits in Schizophrenia
Daniel Javitt
8:30 a.m.
See No Evil: Early-Stage Visual Processing and
Emotion Recognition Deficits in Schizophrenia
Pamela Butler
9:00 a.m.
Fear No Evil: Top-Down and Bottom-Up Processing of
Emotions in Schizophrenia Investigated with Blocked
and Event-Related fMRI
Ruben Gur
9:30 a.m.
To Thine Own Self Be True: Consummatory vs.
Appetitive Pleasure in Schizophrenia
William Horan
Th
Discussion
PA
10:00 a.m.
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Clock Genes, Melatonin & Affective Disorders
Queen’s 4
Clock Genes, Melatonin and Affective Disorders
Chair:
Co-Chair:
Alfred Lewy
William Bunney
8:00 a.m.
Melatonin Receptors As Targets For Modulation Of
Circadian Rhythms
Margarita Dubocovich
8:30 a.m.
In Winter Depression (SAD), the Sweet Spot for the 10
pg/ml Plasma Dim Light Melatonin Onset (DLMO) is
Six Hours Before Mid-Sleep
Alfred Lewy
9:00 a.m.
The Role of Per Genes in Addiction and Depression
Rainer Spanagel
9:30 a.m.
The Molecular Clock as a Target in the Treatment of
Bipolar Disorder
Francesco Benedetti
Th 10:00 a.m.
Discussion
PA
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Endocannabinoid System: Target for Drug Discovery
Queen’s 5
The Endocannabinoid System as Target for Drug Discovery
Chair:
Alexandros Makriyannis
8:00 a.m.
Overview of the Endocannabinoid System, CB1
Receptor Antagonists
8:30 a.m.
Neuroprotection Through Direct and Indirect
Activation of Cannabinoid CB1 Receptors
Ben Bahr
9:00 a.m.
Progress Towards the Development of a PET
Radioligand for Cannabinoid CB1 Receptors
Samuel Gatley
9:30 a.m.
“Gone to Pot”: Emerging Pharmacological Evidence
Implicating Cannabinoid Receptor Function in
Cognition and Psychosis - Implications for
Medications Development
Deepak D’Souza
10:00 a.m.
Discussion
Th
PA
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Noradrenergic Focus: Attention-Deficit Disorders
Queen’s 6
A Noradrenergic Focus on Attention and
Attention-Deficit Disorders
Chair:
Co-Chair:
Randy Blakely
Maureen Hahn
8:00 a.m.
Norepinephrine Transporters: Genetic Variants and
their Impact on Transporter Function and Regulation
Maureen Hahn
8:30 a.m.
Molecular Control of Noradrenergic Gene Expression
and the Impact of Polymorphisms on Attention
Disorders
Kwang-Soo Kim
9:00 a.m.
Role for Norepinephrine in Attention, Learning and
Memory: Insights from Knockout Mice
Steven Thomas
9:30 a.m.
Th
Noradrenergic Pharmacotherapies in Attention Deficit
Hyperactivity Disorder
Thomas Spencer
PA 10:00 a.m.
Discussion
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Kona 5
The Neglected Constituencies: Can Teaching About
Psychopharmacology Change Attitudes and Practices?
Fifth Annual Teaching Session
12:30 p.m.
Introduction
Ira Glick
12:35 p.m.
Medical Students – What is Relevant and How Much
to Cover?
Murray Raskind
12:50 p.m.
NIMH – Intramural and Extramural
Psychopharmacology: Education in a Research
Setting
Donald Rosenstein
1:05 p.m.
Primary Care Physicians & Other Mental Health
Providers – Where Does Psychopharmacology Fit In?
Sidney Zisook
Th
1:20 p.m.
Industry – The Challenge of Teaching at the Academic- PL
Industry Interface
Terence Ketter & Ira Glick
1:35 p.m.
The Public & Media – Education in the Context of
“Stigma” Among Other Issues
Ellen Frank
1:45 p.m.
General Discussion
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Plastic Changes in the Addicted Brain
Kona 5
Plastic Changes in the Addicted Brain: A Glimpse at the
Next Generation of Pharmacotherapies
Chair:
Co-Chair:
Th
Susan Weiss
Ruben Baler
2:30 p.m.
Neuroadaptations in Proteins in the Postsynaptic
Density and Cocaine Addiction
Peter Kalivas
3:00 p.m.
Role of Amygdala ERK in Incubation of Cocaine
Craving
Yavin Shaham
3:30 p.m.
The Endogenous Brain Cannabinoid System and the
Motivational Control of Reinforced Behavior
Steven Goldberg
4:00 p.m.
Why Are Drugs That Enter the Brain Rapidly
Potentially the Most Addictive?
Terry Robinson
4:30 p.m.
Discussion
PA
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Neural Changes in Adolescence & Schizophrenia
King’s 2
Neural Changes in Adolescence and Onset of Schizophrenia
Chair:
2:30 p.m.
Structural MRI of Typical Adolescent Brain
Development
Jay Giedd
3:00 p.m.
Changes in Prefrontal Dopamine Function During
Adolescence and in a Developmental Animal Model of
Schizophrenia
3:30 p.m.
Differential Expression in Schizophrenic Brain of a
DISC1 Molecular Pathway and Association with
DISC1 SNPs
Barbara Lipska
4:00 p.m.
Brain Development in Childhood Onset Schizophrenia
and their Healthy Siblings
Judith Rapoport
4:30 p.m.
Discussion
Th
PA
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Neuregulin 1 - ErbB4 Signaling in Schizophrenia
King’s 1
Neuregulin 1 - ErbB4 Signaling in Schizophrenia
Chair:
Co-Chair:
Steven Arnold
Chang-Gyu Hahn
2:30 p.m.
Neuregulin/ErbB Signaling in Schizophrenia: An
Overview
Cary Lai
3:00 p.m.
Neuregulin 1- ErbB Signaling During Neuronal
Migration in the Developing and Adult Cerebral
Cortex
Eva Anton
3:30 p.m.
Regulation of Synaptic Plasticity by the NRG-1/ErbB
Signaling Pathway: Possible Implications for
Schizophrenia
Andres Buonanno
4:00 p.m.
ErbB4 Signaling is Altered in Schizophrenia
Chang-Gyu Hahn
4:30 p.m.
Discussion
Th
PA
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Autism Spectrum Disorders: Neurobiology & Treatment
King’s 3
Drug Development
Novel Insights into the Neurobiology and
Treatment of Autism Spectrum Disorders
Chair:
Co-Chair:
Larry Young
Husseini Manji
2:30 p.m.
Neuropeptides and the Social Brain: The Value of
Comparative Studies in Autism Research
Larry Young
3:00 p.m.
Molecular Mechanisms of Fragile X Syndrome Reveal
Potential Therapeutic Approaches
Stephen Warren
3:30 p.m.
Clues From Basic Neurodevelopment For New
Treatment Targets in Autism
Pat Levitt
4:00 p.m.
Pharmacological Treatment of Behavioral Symptoms
in Autism
Christopher McDougle
4:30 p.m.
Discussion
Th
PA
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Neural Mechanisms of Extinction
Queen’s 6
Neural Mechanisms of Extinction:
Translating from Rats to Humans
Chair:
Co-Chair:
Gregory Quirk
Scott Rauch
2:30 p.m.
Extinction Training Initiated Shortly After Trauma May
Reduce Spontaneous Recovery, Renewal and
Reinstatement: Implications for Exposure-Based
Psychotherapy
Michael Davis
3:00 p.m.
Retention of Fear Extinction in Rats Depends on
Infralimbic Prefrontal Cortex Plasticity
Gregory Quirk
3:30 p.m.
Neural Mechanisms of Long- and Short-Term Fear
Extinction in Humans
Fred Helmstetter
4:00 p.m.
Magnetic Resonance Imaging Studies of Extinction
Retention in Human Subjects
Scott Rauch
4:30 p.m.
Discussion
Th
PA
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Sex Differences in the Action of Opioids
Queen’s 4
Sex Differences in the Action of Opioids
Chair:
Co-Chair:
Jon-Kar Zubieta
Anne Murphy
2:30 p.m.
Opioid Drugs: Where Sex Makes a Difference
Christopher Evans
3:00 p.m.
Sex Differences in Opiate Pharmacological Effects in
Humans
James Zacny
3:30 p.m.
Sex Differences in the Antihyperalgesic Actions of
Morphine
Anne Murphy
4:00 p.m.
Sex Differences and Gonadal Steroid Influences on
Mu-Opioid Receptor Neurotransmission in Humans
Jon-Kar Zubieta
4:30 p.m.
Discussion
Th
PA
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Whole Genome Association Studies
Queen’s 5
Whole Genome Association Studies:
New Promise for Psychiatric Genetics
Chair:
Co-Chair:
John Kelsoe
Elliot Gershon
2:30 p.m.
Linkage and Association Findings in Bipolar Disorder
and Schizophrenia
Elliot Gershon
3:00 p.m.
Whole Genome Association: Technologies and
Strategies for Application to Psychiatric Illness
John Kelsoe
3:30 p.m.
Dissecting Neuropsychiatric Traits Through WholeGenome Association Analysis
Dietrich Stephan
4:00 p.m.
Analysis Techiniques for Whole Genome Association
Studies
David Cutler
4:30 p.m.
Discussion
Th
PA
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POSTERS
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Poster Session I—Monday
1.
Statistical and Pharmacoeconomic Issues for Annual Alzheimer Screening
J W. Ashford*, Jared R. Tinklenberg, Helena C. Kraemer, Javaid
Sheikh, Ruth O’Hara, Joy Taylor, Jerome A. Yesavage
2.
Alterations in Brain CRF and SRIF in a Transgenic Mouse Model of
Alzheimer’s Disease (Tg2576) Following Treatment with a High Fat Diet
Garth Bissette*, Katherine Ketchum, Jennifer Horgan
3.
Participation in Alzheimer’s Disease Clinical Trials: A Focus on African
American Caregivers
Warachal E. Faison*
4.
Guanfacine Augmentation of Donepezil In The Treatment of Alzheimer’s
Disease
Joseph I. Friedman*, Hillel Grossman, Maureen Fusco, Kristin
Swedish, Jessica Stern, Mary Sano, Kenneth Davis
5.
Anxiolytic Actions of an Estrogen Receptor Beta Agonist in Aged Female
Rats
Robert J. Handa*, T. John Wu, Trent D. Lund
6.
The Neuroanatomical Patterns Associated With Neuropsychiatric
Symptoms In Older Adults With And Without Cognitive Impairment: An
MRI Study
Helen Lavretsky*, Ling Zheng, Michael Weiner, Dan Mungas, Bruce
Reed, Joel Kramer, William Jagust, Helena Chui, Wendy J. Mack
7.
Deficit in the GABAergic Neuroactive Steroid Allopregnanolone in
Alzheimer’s Dementia and Relevance to Neuropathological Disease Stage:
Investigations in Temporal Cortex
Christine E. Marx*, David C. Steffens, Dan G. Blazer, Marian I.
Butterfield, Christine Hulette, John Ervin, Jeffrey A. Lieberman,
Lawrence J. Shampine
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8.
The Allosteric Potentiation of Nicotinic Acetylcholine Receptors by
Galantamine Ameliorates the Cognitive Dysfunction in the AmyloidTreated Mice: Involvement of Dopaminergic Systems
Yukihiro Noda*, Yuan Zhou, Dayong Wang, Akihiro Mouri, Hiroyuki
Mizoguchi, Toshitaka Nabeshima
9.
Early-Onset Behavioral and Synaptic Deficits in a Mouse Model of
Alzheimer’s Disease Are Reversed by Inhibition of Gamma Secretase
Menelas N. Pangalos*, J S. Jacobsen, Thomas A. Comery, Chi-Cheng
Wu, Jeffrey M. Redwine, Robert Arias, Robert Martone, Susan
Aschmies, Kevin P. Atchinson, John H. Morrison, Karen Marquis,
Bloom E. Floyd, Peter H. Reinhart
10.
Frontal, Parietal, and Callosal Degradation in Aging: A Quantitative DTI
Fiber Tracking Study
Adolf Pfefferbaum*, Edith V. Sullivan
11.
Subjective Cognitive Impairment: The Pre-Mild Cognitive Impairment
Stage of Brain Degeneration: Longitudinal Outcome After a Mean of 7
Years Follow-Up
Barry Reisberg*, Steven Ferris, Mony J. De Leon, Carol Torossian,
Sridhar Kadiyala, Wei Zhu
12.
Effect of Catechol-O-Methyl Transferase val 158 Met Polymorphism on
Information Processing in the Prefrontal Cortex during Working Memory
in the Elderly
Fabio Sambataro*, Elesha Kingshott, Saumitra Das, Bhaskar S.
Kolachana, Christie Russo, Allan F. Mirsky, Terry Goldberg, Michael
F. Egan, Andreas Meyer-Lindenberg, Joseph H. Callicott, Daniel R.
Weinberger, Venkata S. Mattay
13.
Serotonin Modulates Longevity and Global Gene Expression in the
Mammalian Brain
Etienne Sibille*, Jing Su, Samuel Leman, A.M. Le Guisquet, Rene
Hen, Catherine Belzung
14.
PET Studies of Cholinergic Modulation of Serotonin in Alzheimer Disease
(AD)
Gwenn Smith*, Elisse Kramer, Carol Hermann, Yilong Ma, Margaret
Kirshner, David Eidelberg, Bruce Pollock
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15.
Stress History and Breast Cancer Recurrence
Oxana Palesh, Lisa D. Butler, Cheryl Koopman, Helena C. Kraemer,
Robert Carlson, David Spiegel*
16.
Benefits of Memantine/Donepezil Treatment on Behavior in Moderate to
Severe AD Using Factor-Analytically Derived Subscales
Pierre Tariot*, Jeffrey Cummings, Jason Olin
17.
Is Translational Research Monkey Business: The Journey of a Novel
AMPAKINE (CX 717) from Primate to a Human Phase 1B Study with a
Cognitive Impairment Model
Gary Tollefson*, Hank Mansbach, Samuel Deadwyler
18.
Cholinergic Receptor Systems in Cocaine-Addicted Subjects: Alterations
in Regional Cerebral Blood Flow
Bryon Adinoff*, Mark J. Williams, Susan E. Best, Tanya Zielinski,
Thomas S. Harris, Erica R. Schreffler, Michael D. Devous
19.
C-fos Activation Correlates with Cocaine Preference in Adolescent Rats
Susan L. Andersen*, Lucinda Kussmaul, Lee Napierata
20.
A Primer on Multivariate Methods for Pharmacoepidemiology: Cocaine
Dependence Illustration
James C. Anthony*
21.
Extinction-Induced Up-Regulation in AMPA Receptors Attenuates
Sensitization to Cocaine and D2 Receptor Stimulation
Ryan K. Bachtell*, Lisa Monteggia, Rachael L. Neve, David W. Self
22.
Comparative Molecular Field Analyses of Amphetamine, Cocaine, and
Antidepressant Recognition at Serotonin Transporter Mutants Reveals
Contributions of Transmembrane Helix III to Ligand Binding
Eric L. Barker*, Crystal C. Walline
23.
Effects of Standard Dopaminergics and Comparison of D3 and D2
Receptor Ligands on Choice Between Concurrently Available Cocaine and
Food in Rats
Andrew C. Barrett*, S S. Negus, Amy H. Newman, Peter Grundt, S B.
Caine
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24.
Behavioral And Neurochemical Effects Of Chronic Exposure To D2
Agonist Treatment In Monkeys
Jack Bergman*, Walter Tornatzky, Frank Tarazi
25.
Neurotensin System Genes and Susceptibility to Cocaine-induced
Psychosis
Elisabeth B. Binder*, Yilang Tang, Charles B. Nemeroff, Joseph F.
Cubells
26.
Relationships Between State Policies and the Availability of Services for
HIV/AIDS, Hepatitis C Viral Infection, and Sexually Transmitted
Infections in Substance Abuse Treatment Programs
Lawrence S. Brown*, Steven Kritz, John Rotrosen, Sherryl Baker, Jim
Robinson
27.
N-3 Polyunsaturated Fatty Acids Decrease Feelings Of Anger In A
Population Of Substance Abusers
Laure Buydens*, Marc Branchey, Alec Roy
28.
Reduced Cocaine Self-Administration in Muscarinic M5 Acetylcholine
Receptor-Deficient Mice
Morgane Thomsen, David P. Woldbye, Gitta Woertwein, Anders FinkJensen, Juergen Wess, Simon B. Caine*
29.
Decreased CNS Serotonin Turnover, Early-life Stress, and Initial Response
to Ethanol are Predictors of Ethanol Consumption in Adolescent Rhesus
Macaques
Scott A. Chen*, Christina S. Barr, Melanie L. Schwandt, Stephen G.
Lindell, Daniel Hommer, Susan Shoaf, Stephen J. Suomi, Markku
Linnoila, J D. Higley
30.
Pain and Opioid Addiction: Complex Relationship
Wilson M. Compton*, Yonette Thomas, Kevin P. Conway, Marc D.
Brodsky
31.
Attenuation of Ethanol and Sucrose-Seeking and Intake Following Chronic
Acamprosate or Naltrexone Treatment
Cristine Czachowski*, Michael DeLory
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32.
Insulin And Amphetamine: What’s Up With Dat?
Lynette Daws*, W A. Owens, Adrian K. France, Rajkumar Sevak,
Aurelio Galli, Charles P. France
33.
Stress, Alcohol, and Fluvoxamine: Composing the Score for a Dissonant
ConSERT
Nicole L. Baganz Strode, Jaclyn L. Munn, Janel M. Boyce-Rustay,
Andrew Holmes, Lynette Daws*
34.
An Association Study of Adenosine Receptor Gene Polymorphisms and
Acute Responses to Caffeine in Light- or Non-Caffeine Users
Harriet De Wit*, Emma Childs, Christa Hohoff, Jurgen Deckert
35.
Dual Diagnosis and Drinking Behaviors in an Outpatient Treatment
Seeking Sample of Adolescents with Alcohol Use Disorders
Deborah Deas*, Himanshu Upadhyaya, Suzanne Thomas
36.
A Double Blind Placebo Controlled Trial of Bupropion Added to Nicotine
Patch and Cognitive Behavioral Therapy in Smokers with Current or Past
Unipolar Depressive Disorder
A. Eden Evins*, Jonathan E. Alpert, Joel Pava, Timothy J. Petersen,
Amy H. Farabaugh, Maurizio Fava
37.
Genomic Screen for Loci Associated with Marijuana, Stimulant and Drug
Dependence in Mission Indians: Relation to Body Mass Index
Cindy L. Ehlers*, Kirk C. Wilhelmsen
38.
The Effects of Exogenous Progesterone on Cocaine Self-Administration in
Women
Suzette M. Evans*, Richard W. Foltin
39.
Differences in the Dopamine System Correspond to Individual Differences
in Pavlovian Conditioned Approach Behavior
Shelly B. Flagel*, Tracy Simmons, Stanley J. Watson, Terry Robinson,
Huda Akil
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40.
Differential Roles for the Basolateral Amygdala and Medial Prefrontal
Cortex in Extinction and Cue-Induced Reinstatement of Food-Seeking
Behavior
Ryan J. McLaughlin, Stan B. Floresco*
41.
The Role of the Basolateral Amygdala in Consolidation of StimulusReward Associations and Subsequent Conditioned Cued-Reinstatement of
Cocaine Seeking
Rita A. Fuchs*, Matthew W. Feltenstein, Ronald E. See
42.
Regulation of Alcohol-Heightened Aggression by Dorsal Raphe and
Prefrontal Cortical 5-HT1B Receptors: Evidence from Microinjection and
Microdialysis Studies in Mice
Sara P. Faccidomo, Makoto Bannai, Jeremy Maggin, Klaus A.
Miczek*
43.
Evidence of White Matter Pathology in First-Episode Manic Adolescents
with Bipolar Disorder: A Diffusion Tensor Imaging Study
Caleb M. Adler*, John Adams, Melissa P. DelBello, Scott K. Holland,
Vince Schmithorst, Ari Levine, Kelly Jarvis, Stephen M. Strakowski
44.
Quetiapine Efficacy in Bipolar Adolescents with Depressive Symptoms
Drew H. Barzman, Caleb M. Adler*, Melissa P. DelBello, Kevin E.
Stanford, Robert A. Kowatch, Stephen M. Strakowski
45.
Measurement of Brain Betabolites in Type 2 Diabetes and Depression
Using Proton Magnetic Resonance Spectroscopy
Olu Ajilore*, E Haroon, C Darwin, N Binesh, A Thomas, S Kumaran,
J Miller, A Kumar
46.
Escitalopram Responders Have Higher Quality of Life Scores Than
Placebo Responders
George Alexopoulos*, Andrew Korotzer, Anjana Bose, Khalil Saikali
47.
Gender Differences in Sleep Regulation in Depressed Adults and Healthy
Controls
Roseanne Armitage*, Robert Hoffmann
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48.
Glutamate Transporter Gene (SLC1A1) Associated with Obsessive
Compulsive Disorder
Paul D. Arnold*, Tricia Sicard, Eliza Burroughs, Margaret A. Richter,
James L. Kennedy
49.
A Study of Long-Acting, Injectable Risperidone in Frequently Relapsing
Bipolar Disorder: Preliminary Findings
Earle Bain*, Georges Gharabawi, Julie Locklear, Ibrahim Turkoz,
Deborah Yurgelun-Todd
50.
Association of an Ancient CRH Gene Haplotype with HPA Axis Activity
in Rhesus Macaques
Christina S. Barr*, Timothy K. Newman, Stephen J. Suomi, Robert
Lipsky, David Goldman, J D. Higley
51.
Regional Cerebral Metabolism and Anxiety Symptoms in Bipolar
Depression: Effects of Levothyroxine
Michael Bauer*, Edythe D. London, Steven M. Berman, Natalie
Rasgon, Mark A. Mandelkern, Bradley Voytek, Peter C. Whybrow
52.
Duloxetine: Meta-Analyses of Suicidal Behaviors and Thoughts in Clinical
Trials for Major Depressive Disorder
Nayan V. Acharya, Amy S. Rosen, John P. Polzer, Deborah N. DSouza,
David G. Perahia, Patrizia A. Cavazzoni, Charles M. Beasley*, Ross J.
Baldessarini
53.
Generalized Anxiety and Pain: Associations and Implications
Katja Beesdo*, Frank Jacobi, Hans-Ulrich Wittchen
54.
Brain Regional α-[11C]Methyl-L-Tryptophan Trapping in Medication-Free
Patients With Obsessive Compulsive Disorder
Alexandre Berney, Marco Leyton, Paul Gravel, Pedro Rosa-Neto, C
Todorov, Debbie Sookman, Gilbert Pinard, Pierre Blier, Mirko Diksic,
Chawki Benkelfat*
55.
Antidepressant Drug Combination from Treatment Initiation to Improve
Therapeutic Response in Major Depression
Richard Bergeron*, Philippe Tremblay, Herbert E. Ward, Chantal
Hebert, Pierre Blier
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56.
Subjective Evaluation of the Long-Term Cognitive Effects of
Electroconvulsive Therapy
Robert M. Berman*, Joan Prudic, Mark Olfson, Harold A. Sackeim
57.
Pharmacological Dissection of the Effect of Risperidone on SSRI-Induced
Changes of Norepinephrine Neuronal Firing
Pierre Blier*, Eliyahu Dremencov, Mostafa El Mansari
58.
Activity of a Selective Galanin-3 Receptor (GAL3) Antagonist In Acute
and Chronic Behavioral Models of Anxiety and Depression
Thomas P. Blackburn, Chad J. Swanson, Toni D. Wolinsky, Michael J.
Konkel, Mary M. Walker, Margaret Durkin, Roman P. Artymyshyn,
Kelli E. Smith, Kenneth A. Jones, Douglas A. Craig, Christophe P.
Gerald, Theresa A. Branchek*
59.
Attention Bias to Threat in Bipolar Children With or Without Comorbid
Anxiety Disorders
Melissa A. Brotman*, Brendan A. Rich, Mariana Schmajuk,
Christopher S. Monk, Karin Mogg, Brendan P. Bradley, Daniel S.
Pine, Ellen Leibenluft
60.
Post-Retrieval Propranolol Weakens Longstanding Traumatic Memories
Alain Brunet*, Scott P. Orr, Jacques Tremblay, Karim Nader, Roger K.
Pitman
61.
Serotonin Transporter Polymorphism Association with Neuroticism and
Depression: A Controversy Evaluated
Margit Burmeister*, Srijan Sen, Debashis Ghosh
62.
A Pilot Controlled Trial of Bupropion vs. Es-Citalopram in Generalized
Anxiety Disorder (GAD)
Alexander Bystritsky*, Lauren Kerwin, Samuel Eiduson, Tanya
Vapnik
63.
Serotonin Transporter Binding in Unmedicated Bipolar Disorder Subjects
using [Carbon-11] DASB and Positron Emission Tomography
Dara M. Cannon*, Masahiro Ichise, Stephem Fromm, Allison C.
Nugent, Denise Rollis, Shilpa K. Gandhi, Wayne C. Drevets
96
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64.
Depressive-Like Effects of the Kappa-Opioid Receptor Agonist Salvinorin
A on Behavior and Neurochemistry in Rats
William A. Carlezon*, Cecile Beguin, Jennifer A. DiNieri, Michael H.
Baumann, Michele R. Richards, Mark S. Todtenkopf, Richard B.
Rothman, Zhongze Ma, David Y. Lee, Bruce M. Cohen
65.
Prefrontal Neurometabolite Changes Following Lamotrigine Treatment in
Adolescents with Bipolar Depression
Kiki Chang*, Kim Gallelli, Meghan Howe, Kirti Saxena, Christopher
Wagner, Daniel Spielman, Allan Reiss
66.
The ERK Pathway in Left Anterior Cingulate Cortex Modulates
Locomotive and Hedonic Activities
Guang Chen*, Thomas Creson, YanLei Hao, Sharon Engel, Husseini
K. Manji
67.
Glucocorticoid Modulation of TPH2 Protein in Raphe Nuclei and Frontal
Cortical 5-HTP Levels in C57/Bl6 Mice
Janet Clark*, Lee-Yuh Pai, Rachel Conley, Rosemarie B. Flick, Ildiko
Szalayova, Eva Mezey, Peter H. Hutson, Ariel Deutch, Susan P.
Rohrer, Osvaldo Flores
68.
Ontogeny of Individual Differences in Emotional Reactivity
Sarah Clinton*, John D. Stead, Sue Miller, Delia Vasquez, Stanley
Watson, Huda Akil
69.
A Pilot Study of the Effect of Omega-3 Fatty Acids on Heart Rate
Variability in Anxiety Disorders
Kathryn M. Connor*, Wei Zhang, Victoria Payne, Lana Watkins,
Jonathan Davidson
70.
Adjunctive Eszopiclone and Fluoxetine in Major Depressive Disorder and
Insomnia: Effects on Sleep and Depression
Mark Corrigan*, W V. McCall, Maurizio Fava, Robert Rubens,
Thomas Wessel, Judy Caron, David Amato, Thomas Roth
71.
Engraftment of a Monoaminergic Cell Line within Affective Neural
Circuitry
Miles G. Cunningham*, Rachael Donalds, William Carlezon, Susan
Anderson, Lee Napierata, Kwang-Soo Kim, Dong-Wook Kim
97
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72.
Cardiovascular Effects of Duloxetine: Preclinical and Clinical Findings
Michael J. Detke*, Smriti Iyengar, Judith W. Henck, Frank Bymaster,
John T. Callaghan, Mary Pat Knadler, Joachim F. Wernicke, Michael
E. Thase
73.
A Psychosocial Approach to Depression in Parkinson’s Disease
Roseanne D. Dobkin*, Lesley A. Allen, Matthew Menza
74.
Serotonin Attenuates Mating-Induced Glutamate Activity in the Medial
Preoptic Area: Implications for Impaired Libido Resulting from SSRIs
Juan M. Dominguez*, Mario Gil, Jessica H. Brann, Elaine M. Hull
75.
Association of the Functional -1019C/G 5-HT1A Polymorphism with
Decreased Prefrontal Cortex Activation Measured with 3T fMRI in Panic
Disorder
Katharina E. Domschke*, Miriam Braun, Patricia Ohrmann, Thomas
Suslow, Harald Kugel, Jochen Bauer, Christa Hohoff, Anette Kersting,
Almut Engelien, Volker Arolt, Walter Heindel, Juergen Deckert
76.
Membrane Localization of the G protein Gsα is Altered in Post-Mortem
Brain of Depressed Suicide Victims: Possible Disruption of Plasma
Membrane Rafts
Robert Donati*, Justin Brown, Xinguo Ren, Yogesh Dwivedi, Robert
Conley, Ghanshyam Pandey, Mark M. Rasenick
77.
Lithium Normalizes Dendritic Localization of Val66met Polymorphism of
Brain-Derived Neurotrophic Factor (BDNFmet): Therapeutic Implications
Jing Du*, Kastuji Suzuki, Guhan Nagappan, Yun Wang, Bai Lu,
Husseini Manji
78.
Serotonin Transporter Activity Modulates 5-HT1B-Induced Alterations in
Prepulse Inhibition and Locomotion: Implications for Obsessive
Compulsive Disorder and Panic Disorder
Stephanie C. Dulawa*, Kerri A. Holick, Mark S. Ansorge, Rene Hen,
Jay A. Gingrich
79.
Underdiagnosis of Psychotic Symptoms in Patients with Bipolar Mania
David L. Dunner*, Carla M. Canuso, Cynthia A. Bossie, Young Zhu
98
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80.
Olanzapine/Fluoxetine Combination Versus Lamotrigine in the Long-Term
Treatment of Bipolar I Depression
Eileen Brown, David Dunner*, David Adams, Elisabeth Degenhardt,
Mauricio Tohen, Douglas Williamson, John Houston
81.
A Comparison of ETRANK, MMRM and LOCF Analyses of Eighteen
Placebo-Controlled Venlafaxine Clinical Trials for the Treatment of Major
Depressive Disorder
Richard Entsuah*, David V. Sheehan, Michael E. Thase, Ying Zhang
82.
Children of Depressed Mothers in an Urban Primary Care Population
Adriana Feder*, Min Tang, Virginia Warner, Angelique Alonso, Eva
Barranco, Daniel J. Pilowsky, Helena Verdeli, Priya Wickramaratne,
Myrna M. Weissman
83.
The DID Anhedonia Rating Scale: Results of the First Validation Study
James M. Ferguson*, Ken Evans, Terry Sills, Heather McDonald
84.
Passive Avoidance Learning and Response Reversal During Tryptophan
Depletion
Elizabeth Finger*, Abigail Marsh, Niveen Kamel, Karina Peschardt,
Meena Vythilingam, Daniel Pine, James Blair
85.
Cognitive Performance in Bipolar Disorder: A Processing Efficiency
Account
David E. Fleck*, Paula K. Shear, Robert A. Kowatch, Stephen M.
Strakowski
86.
A Pilot Trial of Escitalopram for Depression in Perimenopausal Women
Marlene P. Freeman*, Rebecca Hill, Barbara H. Brumbach, Alan J.
Gelenberg
87.
Modafinil in the Treatment of Bipolar Depression: A Placebo-Controlled
Trial
Mark A. Frye*
88.
Epigenetic Determinants of GAD1/GAD67 (2q31.1) Expression in Human
Prefrontal Cortex
Hsien-Sung Huang, Schahram Akbarian*
99
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89.
Asenapine, a Novel Psychotherapeutic Agent with Efficacy in Positive and
Negative Symptoms During Acute Episodes of Schizophrenia: A
Randomized, Placebo- and Risperidone-Controlled Trial
Steven G. Potkin, Miriam Cohen, Ross A. Baker, Anil S. Jina, Steven
Nettler, Larry Alphs*, John Panagides
90.
Training for Assessment of Negative Symptoms of Schizophrenia Across
Languages and Cultures Utilizing the Negative Symptom Assessment
Scale
Larry Alphs*, David G. Daniel, Dawn Velligan, John Bartko, John
Panagides, John Davis
91.
Insulin And Igf-1 Reverse Mitochondrial, Energy Metabolism, Proteasome,
And Neuronal Plasticity Gene Decreases Of Schizophrenia In An MrnaBased Screen For Antischizophrenia Agents
C. A. Altar*, Rachel A. Hunt, Jurata W. Jurata, Eric Derby, Paul
Gallagher, Andrew Lemire, Pascal Laeng
92.
A Double-Blind Randomized Trial of a Single Dose of Placebo,
Haloperidol, and Risperidone in Healthy Volunteers
Celso Arango*, Juan Francisco Artaloytia, Adrienne Lahti, Javier
Sanz, Ana Pascual, Pedro Cubero, David Prieto, Tomas Palomo
93.
Corticotropin-Releasing Factor (CRF) Impairs Sensorimotor Gating In The
Sprague-Dawley Rat: Reversal By Clozapine And Raclopride
Isabel C. Arrillaga-Romany*, Ronald P. Hammer
94.
Type of Symptom Remission and Treatment Outcomes in the Long-Term
Treatment of Patients with Schizophrenia
Haya Ascher-Svanum*, Baojin Zhu, Douglas Faries, Bruce J. Kinon,
John M. Kane
95.
PCP-Disrupted Social Interaction Paradigm in Rats: Differential Effects of
Typical and Atypical Antipsychotics: Putative Role of α2-Adrenoceptor
Antagonism?
Louisa Douglas, Nicole Golembo, Hilde Duytschaever, Barbara
Biemans, Sahana Nayak, David Ashton*
100
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96.
Predictors of Patient Satisfaction with Medication in Patients with
Schizophrenia
A G. Awad*, Andrew Greenspan, Colette Kosik-Gonzalez, Young
Zhu, Cynthia A. Bossie, Amir H. Kalali, Georges M. Gharabawi,
Michael Davidson
97.
Targeting the Cystine-Glutamate Antiporter to Attenuate the Behavioral
and Neurochemical Effects in the Phencyclidine Rodent Model of
Schizophrenia
David Baker*, Aric Madayag, Eric Haschke, Rostian Akpor-Mensah
98.
NRG-1 Protein Levels in Patients with Schizophrenia, Bipolar Disorder
and Major Depression
Senda Beltaifa*, Maree J. Webster, Cynthia Shannon Weickert
99.
Alterations of Postsynaptic AMPA Receptor Trafficking in the Anterior
Cingulate Cortex in Elderly Schizophrenics
Monica Beneyto*, Arjune K. Rama, Vahram Haroutunian, James H.
Meador-Woodruff
100.
AVE1625, a Cannabinoid CB1 Antagonist, as a Co-Treatment for
Schizophrenia: Improvement in Cognitive Function and Reduction of
Antipsychotic-Side Effects in Animal Models
Beth Borowsky*, Rachel Stevens, Black Mark, Senyah Yaw, Nancy
Rogacki, Odessa Giardino, Odile Piot-Grosjean, Jeremy Pratt, Robert
Lenox
101.
Divergence of PPI Deficits and P50 Suppression Deficits in Schizophrenia
Patients Point to Two Dissociable Endophenotypes: Implications for
Genetic Analyses in the COGS Project
David Braff*, Gregory Light, Kristin Cadenhead, Joyce Sprock, Neal
Swerdlow
102.
Elevated Prenatal Homocysteine as a Risk Factor for Schizophrenia
Alan S. Brown*, Teodoro Bottiglieri, Catherine A. Schaefer, Charles P.
Quesenberry, Liyan Liu, Michaeline Bresnahan, Ezra S. Susser
101
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103.
Evidence That a DTNBP1 Risk Haplotype is Associated with Negative
Symptoms and Cognitive Dysfunction in Patients with Schizophrenia
Katherine E. Burdick*, Pamela DeRosse, Birgit Funke, Todd Lencz,
Philip R. Szeszko, John M. Kane, Raju Kucherlapati, Anil K.
Malhotra
104.
Hypometabolic Medial-Frontal Effects of Chronic Intermitent PCP
Exposure in Rats Assessed with High Resolution Magic Angle Spin 11.7T
Proton Magnetic Resonance Spectroscopy
Juan R. Bustillo*, Nora Perrone-Bizzozero, Rodrigo Paz, Gayle
Griffith, Matthew Galloway
105.
The Eyes Don’t Have It: Face Processing in Schizophrenia
Pamela D. Butler*, Arielle Tambini, Yovel Galit, Maria Jalbrzikowski,
Rachel Ziwich, Nancy Kanwisher, Uriel Heresco, Shlomo Bentin,
Daniel C. Javitt
106.
Neurocognitive Deficits in Prodromal and First Episode Schizophrenia are
Stable and Predictive of Social Functioning
Kristin Cadenhead*, Angela Eastvold, David Braff, Robert Heaton
107.
The Consortium on the Genetics of Schizophrenia (COGS): Recruitment
and Assessment Methods in a Multi-Site Collaboration
ME Calkins*, DJ Dobie, KS Cadenhead, A Olincy, DL Braff
108.
Prefrontal Cortex Inefficiency During Working Memory in Unaffected
Siblings of Patients with Schizophrenia: A Replication
Joseph H. Callicott*, Steven Sust, Hao-Yang Tan, Venkata S. Mattay,
Joshua Buckholtz, Michael F. Egan, Daniel R. Weinberger
109.
Promoter Specific Alterations of BDNF mRNA in Frontal Cortex in
Patients with Schizophrenia
Hope L. Cassano*, Thomas M. Hyde, Amy Deep-Soboslay, Joel E.
Kleinman, Cynthia Shannon Weickert
110.
Trait vs. State Markers for Schizophrenia: the Case of Visual Motion
Processing
Yue Chen*, L Cinnamon Bidwell, Philip Holzman
102
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111.
Identification and Characterization of Behavioral Plasticity Genes in
Drosophila
William Cho*, Fred Wolf, Ulrike Heberlein
112.
Confirmation of the Association of 10 Genes with Atypical Anti-Psychotic
Treatment Emergent Weight Gain in a Cohort with an Obesity Phenotype
Sandra Close Kirkwood*, Richard D. Hockett, Nitai D.
Mukhopadhyay, Dong-Jing Fu, R. Arlen Price, John Blanchard,
Dennis Ballinger, David R. Cox, Alan Breier
113.
Patient-Reported and Clinician-Rated Depressive Symptoms in the
Treatment of Schizophrenia
Robert Conley*, Haya Ascher-Svanum, Baojin Zhu, Douglas Faries,
Bruce Kinon
114.
Investigating Cortical Inhibition as a Potential Mechanism of Atypicality in
the Antipsychotic Clozapine Using Transcranial Magnetic Stimulation
Zafiris J. Daskalakis*, Sarah I. Fountain, Robert Chen
115.
Null Mutation of the Alpha-2A Adrenoceptor in Mice Fails to Alter
Visuospatial Attention or the Performance Enhancing Effects of
Guanfacine
J David Jentsch*
116.
Ziprasidone Dosing Study in Pediatric Patients with Bipolar Disorder,
Schizophrenia, or Schizoaffective Disorder
Mark Versavel, Melissa P. DelBello*, Kathleen Ice, Robert Kowatch,
David Keller, Jeffrey Miceli
117.
Brain Structural and Functional Deficits in Subjects at High Genetic Risk
for Schizophrenia
Lynn E. DeLisi*, Kamila Szulc, Hilary C. Bertisch, Kyle Brown,
Magda Majcher, Sarah Branch, David Mack, Raj Sangoi, Matthew
Hoptman, Craig Branch
118.
Population Pharmacokinetic Analysis of Drug-Drug Interactions Among
Risperidone, Bupropion, and Sertraline in CF-1 Mice
Lindsay DeVane*, Jun-Sheng Wang, Brian Gibson, Jennifer Donovan,
John Markowitz, Haojie Zhu
103
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119.
A Data-Driven Approach for Understanding the Stages of Schizophrenia
John Docherty*, Stephen Rodriguez, Colette Kosik-Gonzalez, Cyndi
Bossie, Georges Gharabawi, Sam Siris
120.
Deficits in PFC Activity in Schizophrenia Patients During the Maintenance
and Response Selection Phases of Working Memory
Naomi R. Driesen*, Hoi-Chung Leung, R. T. Constable, Pawel
Skudlarski, Patricia S. Goldman-Rakic, John H. Krystal
121.
Reduced Hospitalisation in Patients with Schizophrenia Initiated with
Risperidone Long-Acting Injection (LAI): 3 Month Follow-Up from the eSTAR Database
Dieter Naber, Harry Hustig, Dominique Rosillon, Lennart Wetterberg,
Sue Caleo, Mike Ingham, Bo Eriksson*, An Jacobs
122.
Natural Prepulse Inhibition Deficits in Brattleboro Rats Respond to
Valproic Acid Augmention of Clozapine: Further Support for the
Predictive Validity of this Animal Model
David Feifel*, Paul Shilling, Gilia Melendez
123.
Corollary Discharge Failure in Schizophrenia is Related to Severity of
Auditory Hallucinations: fMRI Evidence
Judith M. Ford*, May Gray, Gary Glover, William O. Faustman, Susan
L. Whitfield, Daniel H. Mathalon
124.
Mice Deficient for an Immediate Early Gene Show a Heightened Response
to Environmental Stressors Consistent with a Schizophrenia Phenotype
Amelia Gallitano-Mendel*, David Wozniak, Maureen Boyle, Louis
Muglia, Jeffrey Milbrandt
125.
A Pilot Study Assessing the Effects of Dar-0100 (A Dopamine D1 Full
Agonist) on Regional Brain Activity and Task-Specific Activation in
Patients with Schizophrenia
Mark S. George*, Ziad Nahas, Berry Anderson, F. A. Kozel, Qiwen
Mu, Chris Molnar, Michael Knable, Prabhavathi Fernandes, David
Nichols, Richard Mailman
104
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126.
Neuropsychological Deficits in Non-Smokers with Schizophrenia: Effects
of a Nicotinic Antagonist
Tony P. George*, Kristi A. Sacco
127.
Exploring the Evidence for a Relationship Between Symptomatic
Remission and Improvement in Functioning in Patients With Schizophrenia
Georges Gharabawi*, Cyndi Bossie, Steve Rodriguez, Ibrahim Turkoz,
George Simpson
128.
Appraising Neurocognitive Endophenotypes for Schizophrenia
David C. Glahn*, Laura Almasy, Jaun Manuel Peralta, Gary M. Burk,
Jose Estrada, Naxhielli Meyenberg, Mariana Pereira Castro, Humberto
Nicolini, Henriette Raventos, Michael A. Escamilla
129.
Placebo-Controlled, Add-On Trial of CX516 (Ampakine) in Schizophrenia
Donald C. Goff*, J. S. Lamberti, Alexander Miller, Jayendra K. Patel,
Theo Manschreck, Oliver Freudenreich, Michael F. Green, Andrew
Leon, Steven Johnson
130.
The Trajectory is The Story: Cortical Gray Matter Changes During
Adolescence In Childhood Onset Schizophrenia Evolve Into The Adult
Pattern By Age 25
Nitin Gogtay*, Deanna Greenstein, Jay Giedd, Liv Clasen, Alexandra
Sporn, Marge Lenane, Jason Lerch, Alan Evans, Judith Rapoport
131.
Reelin (RELN) Promoter Hypermethylation In Gaba Neurons In
Schizophrenia
Dennis R. Grayson*, Ying Chen, Rajiv P. Sharma, Alessandro
Guidotti, Erminio Costa
132.
The Consortium on the Genetics of Schizophrenia (COGS): Preliminary
Heritability Analyses of Endophenotypic Measures for Schizophrenia
Tiffany A. Greenwood*, David L. Braff, Neal R. Swerdlow, Michael F.
Green, Keith Nuechterlein, Allen D. Radant, William S. Stone, Ann
Olincy, Raquel Gur, Nicholas J. Schork
133.
Convergence of Cognitive Improvement with Development of Clinical
Remission in Schizophrenia
Philip D. Harvey*, Antony Loebel, Christopher R. Bowie
105
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134.
Cognitive and Functional Improvement with Long Term Treatment with
Long-acting Risperidone
Philip D. Harvey*, Gahan Pandina, Robert M. Bilder, Steven
Rodriguez, Ibo Turkoz, Georges Gharabawai
135.
Cognitive Coping and Illusion of Control Can Both Modulate
Hypothalamic-Pituitary-Adrenal Response to Pharmacological Activation
James L. Abelson*, Samir Khan, Israel Liberzon, Hedieh Briggs,
Elizabeth A. Young
136.
Mifepristone for the Prevention of Olanzapine-Induced Weight Gain in
Rats
Katherine L. Beebe*, Thaddeus Block, Charles DeBattista, Christine
Blasey, Alan F. Schatzberg
137.
Ovarian Steroids Suppress the Apoptosis-Inducing Protein JNK1 in the
Dorsal Raphe Region of Macaques
Cynthia L. Bethea*, Lisa J. Smith
138.
Effects of Left Prefrontal rTMS on Laboratory, Neuropathic and PostOperative Pain
Jeffrey J. Borckardt*, A. R. Smith, Mitchell Weinstein, Scott T.
Reeves, Stephen Gibert, Audrey Barry, F. A. Kozel, Mark S. George
139.
Indiplon Dose-Response Analyses For Objective and Subjective Measures
of Sleep
Brian Corrigan*, Raymond Miller, Phillip B. Chappell, Robert Farber,
Danielle Ouellet, Dimitri E. Grigoriadis
140.
Plasma L-Tryptophan Depletion and Loading Time-Course and Side-Effect
Comparison of 50 and 100g Formulations
Donald M. Dougherty*, D.M. Marsh, C.W. Mathias, M.A. Addicott,
A.A. Jagar, C.J. Morgan, A.A-B. Badawy
141.
Prevalence of Intact Decision-Making Capacity for Research Among
People with Schizophrenia Using Two Standards
Laura B. Dunn*, Barton W. Palmer, Dilip V. Jeste
106
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142.
Methamphetamine-Induced Dopamine Complex Formation: A Role For
Reactive Oxygen Species and Dopamine Receptors
Anthony J. Baucum, Kamisha L. Johnson-Davis, Glen A. Cook, Glen
R. Hanson, Annette Fleckenstein*
143.
Response to Methylphenidate in Symptoms of Most Concern to Parents of
Preschool Children with Developmental Disorders
Jaswinder K. Ghuman*, Rick Cruz, Ron Wright, Harinder S. Ghuman,
Alan Gelenberg
144.
Inhibition of Dopamine Transporter Activity by Cannabinoids
Andrea Giuffrida*, David A. Price, Lynette C. Daws, W A. Owens,
Georgianna G. Gould, Alan Frazer, Alexander Seillier, James L.
Roberts
145.
Differences in Cognitive Function and Acute Sedative Effects of
Risperidone and Quetiapine Among Individuals with Stable Bipolar I
Disorder
Howard A. Hassman*, Steven J. Glass, Luella Engelhart, Lian Mao,
Stephen Rodriguez, Georges Gharabawi, Robert Bilder, David G.
Krefetz, Maria Pinho, Harbans Lal
146.
Family Study of Binge Eating Disorder
James I. Hudson*, Justine K. Lalonde, Cynthia M. Bulik, Scott J.
Crow, Susan L. McElroy, Nan M. Laird, Ming T. Tsuang, B. T. Walsh,
Norman R. Rosenthal, Harrison G. Pope
147.
Duloxetine: Summary of Time to Response in a Preclinical and a Clinical
Model of Neuropathic Pain
Smriti Iyengar*, Yili L. Pritchett, Jerry A. Hall, Amy S. Chappell,
Joachim F. Wernicke, David J. Goldstein, Rosa M. Simmons, Michael
J. Detke, Shuyi Shen, Deborah N. DSouza, Michael J. Robinson
148.
Seizure Risk Among Patients Participating in Psychopharmacology
Clinical Trials
Arif Khan*, Kenneth Alper, Kelly Schwartz, Russell Kolts, Walter
Brown
107
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149.
Early Life Stress Impairs Memory and Produces Hippocampal
Degeneration in Adult Rats
Therese A. Kosten*, David A. Karanian, Colin N. Haile, Thomas R.
Kosten, Jeansok J. Kim, Priscilla Kehoe, Ben A. Bahr
150.
The Role Of Postsynaptic Alpha-2 Noradrenergic Receptors In The
Modulation Of Cortical Activity
Antonieta Lavin*, Glenn D. Andrews
151.
Effects of Childhood Trauma and Acute Lorazepam on Fear-Related
Cortico-Limbic Brain Reactivity: A Pilot Pharmacological fMRI Study
Royce Lee*, Kin L. Phan, Michael Angstadt, Daniel A. Fitzgerald,
Allan Klock, Michael S. McCloskey, Emil F. Coccaro
152.
Trophic Factors and Adrenergic Function
Dona Lee Wong*, T.C. Tai, David C. Wong-Faull, Robert Claycomb
153.
Functional Outcomes in Adults with Attention-Deficit/Hyperactivity
Disorder Following Treatment with Atomoxetine vs. Placebo
Louise Levine*, Roy N. Tamura, Douglas K. Kelsey, Darryle D.
Schoepp, Albert J. Allen
154.
Abnormal Glutamate and Dopamine Receptor Function in the Striatum of
Alpha-Synuclein Overexpressing Mice
Michael S. Levine*, Nan-Ping Wu, Carlos Cepeda, Eliezer Masliah
155.
Asenapine Preferentially Increases Dopamine (DA) and Acetylcholine
(ACh) Efflux in Rat Medial Prefrontal Cortex (mPFC) and Hippocampus
(HIP)
Zhu Li*, Mohammed Shahid, Herbert Y. Meltzer
156.
Topiramate for the Treatment of Moderate to Severe Binge Eating Disorder
Associated with Obesity A Double-Blind, Placebo-Controlled Study
Susan McElroy*, James I. Hudson, Julie A. Capece, Karen Beyers,
Alan C. Fisher, Norman R. Rosenthal
157.
Effect of Risperidone and Olanzapine on Measures Associated with the
Insulin Resistance Syndrome
Herbert Y. Meltzer*, Yuejin Chen, Karu Jayathilake
108
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158.
Multiple Novel Polymorphisms in the Rhesus Macaque DRD4 5’ UTR are
Associated with Impulsive Behavior
Timothy K. Newman*, Christina S. Barr, Rachel E. Holston, Nicole Y.
Davis, Stephen J. Suomi, David Goldman, J D. Higley
159.
Metabolic Profile in Children and Adolescents with Disruptive Behavior
Disorders Treated with Risperidone
Magali Reyes, Gahan J. Pandina*, Ilse Augustyns, Robert L. Findling
160.
The Association of Fatigue with Poor Virologic Response in Patients
Receiving Interferon-Alpha Plus Ribavirin for the Treatment of Hepatitis C
Charles L. Raison*, Carmine M. Pariante, Lucile Capuron, Bin Chen,
Bobbi J. Woolwine, Paul M. Plotsky, Ira M. Jacobson, Andrew H.
Miller
161.
Randomized, Double-Blind, Placebo-Controlled Study of Armodafinil for
the Treatment of Excessive Sleepiness Associated With Chronic Shift Work
Sleep Disorder
Thomas Roth*, Charles A. Czeisler, James K. Walsh, Keith A.
Wesnes, Michael Williams, Gwendolyn E. Niebler, Sanjay Arora
162.
A Complementary Strategy to Approach the Genetics of Schizophrenia
Dan Rujescu*, Ina Giegling, Annette Hartmann, Just Genius,
Christoph Mulert, Ulrich Hegerl, Heinz Grunze, Pierandrea Mulia,
Claire Birell, Andreas Ruppert, Thomas Meitinger, Martin Keck,
Frauke Ohl, Manfred Ackenheil, Hans-Jurgen Moller
163.
Serotonin Transporter Polymorphism Influences the Prolactin Response to
Tryptophan and Stress
Cynthia M. Kuhn, Kishore Gadde, Saul M. Schanberg*, Douglas A.
Marchuk, Ilene C. Siegler, Richard S. Surwit, Redford B. Williams
164.
5-HT6 Receptor Stimulation Induces Neuroprotective Properties In Vitro
and In Vivo
Lee E. Schechter*, Margaret Zaleska, Mark Bowlby, Danni Liu, Shi
Liang, John A. Harvey, Al Robichaud, Ron Bernotas, Derek Cole,
Kevin Pong
109
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165.
Onset of Antidepressant Action and Acute Efficacy and Safety of
Duloxetine Versus Escitalopram and Placebo in the Treatment of Major
Depressive Disorder
AA Nierenberg*, JH Greist, CH Mallinckrodt, A Prakash, JG Watkin,
A Sambunaris, GD Tollefson, MM Wohlreich
110
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Poster Session II—Tuesday
1.
Diffusion Tensor Imaging in Cocaine Dependence: Evidence for Reduced
Myelin in the Anterior Corpus Callosum
F. Gerard Moeller*, Khader M. Hassan, Joel L. Steinberg, Ignacio
Valdes, Larry Kramer, Ponnada A. Narayana, Alan C. Swann
2.
Effects of Self-Administered and Passive Cocaine Infusions on Dopamine,
Norepinephrine and Corticosterone Concentrations in the Medial
Prefrontal Cortex
Nicholas E. Goeders*, Gennady N. Smagin, Marie F. Lanfranco,
Patricia K. Seitz, Mary L. Thomas, Kathryn A. Cunningham, Vitaly S.
Palamarchouk
3.
Decreased Corticolimbic Responset To Monetary Reward in Cocaine
Addiction: Association with Motivation and Self-Control
Rita Z. Goldstein*, Dardo Tomasi, Nelly Alia-Klein, Lisa A. Cottone,
Lei Zhang, Thomas Maloney, Frank Telang, Elisabeth C. Caparelli,
James M. Swanson, Nora D. Volkow
4.
Interactions Between Nalbuphine, Mood and Hypothalamic-Pituitary-Axis
(HPA) Hormones
Nathalie V. Goletiani*, Jack H. Mendelson, Michelle B. Sholar, Arthur
J. Siegel, Alicja Skupny, Nancy K. Mello
5.
Aripiprazole Decreases Alcohol Drinking in Syrian Golden Hamsters
David T. Chau, Alan I. Green*
6.
Time-Dependent Dissociation Between Accumbal and Amygdalar
Mediation of Cue-Induced Cocaine Seeking
Jeffrey W. Grimm*, Meghan Manaois, Dan Osincup, Amber Fyall,
Barbara Wells
7.
Effects of Baclofen on Cocaine Self-Administration: Opioid-Dependent
and Non-Opioid Dependent Volunteers
Margaret Haney*, Carl Hart, Richard W. Foltin
111
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8.
Modafinil Attenuates Disruptions in Performance and Mood During
Simulated Night Shift Work
Carl L. Hart*, Margaret Haney, Suzanne K. Vosburg, Sandra D.
Comer, Erik Gunderson, Richard W. Foltin
9.
Psychiataric Symptoms Among Outpatients in an Open-Label Trial of
Risperidone for Methamphetamine Dependence
Craig Jaffe*, Andrew J. Saxon, Charles W. Meredith
10.
Gender Differences in Substance Use by Healthcare Professionals in a
State Sample
George A. Kenna*, Robert M. Swift
11.
Intravenous Nicotine Self-Administration in C57BL6/J Mice
Paul J. Kenny*, Athina Markou
12.
Behavioral Pharmacology and Pharmacokinetics of Cocaine Analogs in
Rhesus Monkeys
Heather L. Kimmel*, S S. Negus, Sarah B. Ewing, John R. Votaw,
Mark M. Goodman, F I. Carroll, Nancy K. Mello, Leonard L. Howell
13.
Synergistic Interactions Between “Club Drugs”: Gamma-Hydroxybutyrate
and N-Methyl-D-Aspartate Antagonists
Wouter Koek*, Mandar Khanal, Charles P. France
14.
Six-Month Trial of Bupropion with Contingency Management for Cocaine
Dependence
Thomas R. Kosten*, James Poling, Alison Oliveto, Kishor Gonsai,
Mehmet Sofuoglu, Gerardo Gonzalez, Bridget Martell
15.
Naltrexone and Fluoxetine for Relapse to Heroin Dependence in St.
Petersburg, Russia
Evgeny M. Krupitsky*, Edwin E. Zvartau, Elena V. Verbitskaya,
Charles P. O’Brien, George E. Woody
16.
Are Adolescent Rats Addiction-Prone and Hyperresponsive to Stimulants
Because They Are Hypodopaminergic?
Quentin D. Walker, Joseph M. Caster, Lauren Gerlach, Sarah Parylak,
Sarah Morris, Cynthia M. Kuhn*
112
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17.
Ethanol Does Not Affect Discriminative Stimulus Effects of Nicotine in
Rats
Bernard Le Foll*, Steven R. Goldberg
18.
Blockade of D2/D3 Dopamine Receptors Selectively Impairs Reversal
Learning, but not New Learning, in Monkeys Performing a Visual
Discrimination Task
Buyean Lee*, Edythe D. London, J. D. Jentsch
19.
Endocrine Challenge of the HPA Axis Differentially Modulates Plasma
Deoxycortisosterone and Pregnenolone Levels in Cynomolgus Monkeys
A. Leslie Morrow*, Patrizia Porcu, Laura S. Rogers, Kathleen A.
Grant
20.
The Effect of Dopamine Precursor Depletion on Alcohol SelfAdministration in Men: Individual Differences
Sean P. Barrett, Robert O. Pihl, Chawki Benkelfat, Caroline Brunelle,
Simon N. Young, Marco Leyton*
21.
Examining White Matter Abnormalities in Cocaine Dependence with T2
Relaxography
Kelvin O. Lim*, Bryon A. Mueller, Sheila M. Specker, Jeffrey R.
Wozniak
22.
Variation in the rhNPY Promoter Is Associated with Differences in CSF
Levels of NPY and Alcohol Consumption
Christina S. Barr, Stephen G. Lindell*, Stephen J. Suomi, David
Goldman, J D. Higley
23.
The Effects of CRH-1 Antagonist Antalarmin on Cocaine SelfAdministration and Discrimination
Nancy K. Mello*, S S. Negus, Kenner C. Rice, Jack H. Mendelson
113
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24.
The Effects of ‘Binge’ Cigarette Smoking on Hypothalamic-PituitaryAdrenal Axis Hormones and Mood in Men
Jack H. Mendelson*, Nathalie V. Goletiani, Michelle B. Sholar, Arthur
J. Siegel, Nancy K. Mello
25.
Dose-Dependent Effects of Topiramate on Alcohol Cue Reactivity and the
Subjective Effects of Drinking: Preliminary Data
Robert Miranda*, Peter Monti, Robert Swift, James MacKillop,
Jennifer Tidey, Chad Gwaltney, Damaris Rohsenow
26.
5-HT1B Receptors in Nucleus Accumbens Efferents Can Increase both
Rewarding and Aversive Effects of Cocaine
John F. Neumaier*, Sabiha Barot
27.
Factor Analysis of the Y-BOCS in Autistic Disorder
Evdokia Anagnostou*, William Chaplin, Dryden Watner, Jeremy
Silverman, Eric Hollander
28.
Decreased Cortisol Response to the Trier Social Stress Test in Healthy
Adults with Significant Childhood Adversity
Linda L. Carpenter*, Audrey R. Tyrka, John P. Carvalho, Lauren Wier,
Gerard G. Gagne, Andrea F. Mello, Marcelo F. Mello, George M.
Anderson, Lawrence H. Price
29.
Variable Foraging Demand (VFD) Exposure of Primate Maternal-Infant
Dyads and Impaired Insulin Action in Juvenile Offspring
Jeremy D. Coplan*, Daniel Kaufman, Igor Shorman, Eric L. Smith,
Michael J. Owens, Charles B. Nemeroff, Leonard A. Rosenblum, John
G. Kral, MaryAnn Banerji
30.
Early Postnatal Brain Structure and Development in Humans: Sexual
Dimorphism and Cerebral Asymmetry are Present at Birth
John Gilmore*, Christopher Looney, Yethiraja Vesta, J. K. Smith,
Weili Lin, Jeffery A. Lieberman, Guido Gerig
114
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31.
Oxytocin Increases Social Cognition in Autism
Eric Hollander*, William Chaplin, Ann Phillips, Jennifer Sumner,
Latha Soorya, Evdokia Anagnostou, Stacey Wasserman
32.
Individual Differences in Physiological Regulation and Early Development
of African-American Infants Living in Poverty
Suma Jacob*, Kate Keenan
33.
Developmental Regulation of NCAM in Human Frontal Cortex
L. F. Jarskog*, Patricia F. Maness, Karissa L. Gable, Anthony-Samuel
LaMantia, Jeffrey A. Lieberman, John H. Gilmore
34.
Gender-Specific Longitudinal Changes in Cortical Thickness in Children
and Adolescents
Rhoshel Lenroot*, Philip Shaw, Kristin Taylor, Dede Greenstein, Liv
Clasen, Alan Evans, Jay N. Giedd
35.
Behavioral and Electrophysiological Characterization of the Role of
MeCP2 in the Brain
Lisa Monteggia*, Erika Nelson, Terry Gemelli, Olivier Berton, Linda
Perrotti, Rudolf Jaenisch, Ege Kavalali
36.
A Prospective, Open-Label Study of Atomoxetine for ADHD Symptoms
Associated with Higher-Functioning Pervasive Developmental Disorders
David J. Posey*, Ryan E. Wiegand, Wilkerson Jennifer, Melissa
Maynard, Kimberly A. Stigler, Christopher J. McDougle
37.
Relationship Between Behavior and Neurochemical Changes in Rhesus
Macaques During a Separation Paradigm
Simona Spinelli*, Melanie Schwandt, Kristine Erickson, Stephen
Lindell, Jay Schulkin, Philip Gold, Stephen J. Suomi, J. D. Higley
38.
Dysfunction of Critical Regulators of Serotonergic Signaling Confers
Autism Susceptibility
James S. Sutcliffe*, Ryan J. Delahanty, Harish C. Prasad, Qiao Han,
Lan Jiang, Randy D. Blakely
115
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39.
Cortical and Amygdala Overgrowth in Autism Associated With 5-HTTLPR
Thomas H. Wassink*, Heather Cody, Matthew Mosconi, Eric Epping,
Joseph Piven
40.
The Sp4 Transcription Factor Gene is Critical for Postnatal Development
of Dentate Gyrus in Mice and Associated with Bipolar Disorder in
Humans
Xianjin Zhou*, John Kelsoe, Mark A. Geyer
41.
Genetic Correlates of Cortico-Limbic Activity and Connectivity in Major
Depression
Amit Anand*, Yu Li, Yang Wang, Sujuan Gao, Jingwei Wu, Mark J.
Lowe, Thomas Talavage, John I. Nurnberger, David Goldman, Jill
Murrell
42.
Comparison of the Effects of Tolcapone and Entacapone on Cognition and
fMRI in Normal Volunteers
Jose A. Apud*, Venkata Mattay, Jingshan Chen, Kolachana S. Bhaskar,
Joseph H. Callicott, Guilna Alce, Jennifer Iudicello, Natkai Akbar,
Michael F. Egan, Terry E. Goldberg, Daniel R. Weinberger
43.
Altered Serotonin Transporter Binding After Recovery from Anorexia
Nervosa Using PET and [11C]McN5652
Ursula F. Bailer*, Guido F. Frank, Shannan E. Henry, Julie C. Price,
Carolyn C. Meltzer, Angela Wagner, Claire W. McCohana, Chester A.
Mathis, Walter H. Kaye
44.
CBT vs Sertraline in OCD: Effects on Brain Regional Serotonin Synthesis
Index
Igor Sibon, Marco Leyton, Paul Gravel, Debbie Sookman, Gilbert
Pinard, Mirko Diksic, Chawki Benkelfat*
45.
The Neural Correlates of Social Decision-Making: An Event-Related fMRI
Study
Joshua W. Buckholtz*, Qiang Chen, Steven Sust, Emily M. Drabant,
Beth A. Verchinski, Giuseppe Blasi, Fabio Sambataro, Venkata S.
Mattay, Daniel R. Weinberger, Joseph H. Callicott
116
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46.
Role of Medial Prefrontal Cortex in Intention Deficit in Schizophrenia
Margaret A. Cato*, Bruce A. Crosson, Eric L. Granholm, Gregory G.
Brown
47.
Amygdala Hyperactivity to Angry Faces in Patients with Intermittent
Explosive Disorder
Emil F. Coccaro*, Michael S. McCloskey, Daniel A. Fitzgerald, K.
Luan Phan
48.
Prefrontal Neurochemical Abnormalities in Adolescent Bipolar Disorder
Melissa P. DelBello*, Kim Cecil, Cal Adler, Stephen M. Strakowski
49.
Low Frequency Oscillations of Oxy-Hemoglobin in Brain: A NearInfrared-Spectroscopic Feasibility Study
Adriana Di Martino*, PaoloEmilio Barbano, Michael Milham,
Christopher Hyde, F. Xavier Castellanos
50.
Neural Activation During Encoding of Emotional Faces in Pediatric
Bipolar Disorder
Daniel P. Dickstein*, Brendan A. Rich, Roxann Roberson-Nay,
Deborah T. Vinton, Lisa H. Berghorst, Daniel S. Pine, Ellen Leibenluft
51.
Altered Dorsal or Ventral Prefrontal Morphology May Differentiate Risk
for Schizophrenia or Bipolar Disorder: Preliminary Evidence from in vivo
MRI studies
Vaibhav A. Diwadkar*, Boris Birmaher, Jeffrey J. Nutche, Diana
Dworakowski, David Axelson, David Brent, Debra M. Montrose,
Matcheri S. Keshavan
52.
Emotional Numbing in PTSD: fMRI Neuroimaging of Reward Circuitry
Igor Elman*, Blaise Frederick, Dan Ariely, Steven Dunlap, John
Rodolico, David Penetar, Nina Mazar, Jeannette Cohan, Roger Pitman,
Scott Lukas
117
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53.
Influence of Low and High Dose Hydrocortisone Infusion on
Hemodynamic Response in Amygdala While Viewing Emotional Faces
Kristine Erickson*, Maura L. Furey, Jay Schulkin, Suzanne E. Wood,
Linda Mah, Allison C. Nugent, Wayne C. Drevets
54.
Schematic Faces Evoke Exaggerated Regional Activation Within the
Amygdala in Social Anxiety Disorder
Karleyton Evans*, Christopher I. Wright, Michelle M. Wedig, Mark H.
Pollack, Scott L. Rauch
55.
Medial Prefrontal Cortical Maturation: An fMRI Study of Interference
Processing in Healthy Children
Kate D. Fitzgerald*, Hannah F. Chua, Robert C. Welsh, Stephan F.
Taylor
56.
Increased Dopamine D2/D3 Receptor Binding After Recovery from
Anorexia Nervosa
Guido K. Frank*, Ursula F. Bailer, Wayne C. Drevets, Carolyn C.
Meltzer, Julie C. Price, Walter H. Kaye
57.
PET Imaging of the Serotonin 2a Receptor (5-HT2a) and Sertonin
Transporter (SERT) in Personality Disordered Subjects with Impulsive
Aggressivity
WG Frankle*, PS Talbot, Y Huang, L Iskander, M Goodman, AS
New, D-R Hwang, A Abi-Dargham, M Laruelle, LJ Siever
58.
Subcortical Asymmetries in Bipolar and Attention Deficit/Hyperactivity
Disorders
Jean A. Frazier*, Janis L. Breeze, Nikos Makris, Martha R. Herbert,
David N. Kennedy, Steven M. Hodge, Megan E. Dieterich, Joseph
Biederman, Verne S. Caviness
59.
Increased GABAergic Activity Modulates MR-Visible Glutamate and
Glutamine: Studies with High Resolution Magic Angle Spinning Proton
Magnetic Resonance Spectroscopy (HR-MAS 1H-MRS)
Matthew P. Galloway*, Navid Seraji-Bozorgzad, Kerry L. Murphy,
Shonagh K. O’Leary Moore, Kristen M. Haubenreich, George M.
McKelvey, Aliaksei Pustavoitau, John H. Hannigan, Harold M. Marsh
118
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60.
Computational Anatomy to Assess Growth Pattern of Early Brain
Development in Healthy and Disease Populations
Guido Gerig*, John H. Gilmore, Matthieu Jomier, Sarang Joshi,
Joseph Piven
61.
Altered Pain Processing in Veterans with Posttraumatic Stress Disorder
Elbert Geuze*, Anja Jochims, Christian Schmahl, Herman
Westenberg, Eric Vermetten
62.
Frontal Dopamine D2 Receptor Binding in Neuroleptic-Naive FirstEpisode Schizophrenic Patients Correlates with Positive Psychotic
Symptoms and Predicts Treatment Outcome
Birte Y. Glenthoj*, Hans Rasmussen, Torben Mackeprang, Claus
Svarer, William Baare, Lars Pindborg, Lars Friberg, Ralf
Hemmingsen, Charlotte Videbaek
63.
White Matter Integrity in Kleptomania: A Pilot Study
Jon Grant*, Stephen Correia, Thea Brennan-Krohn
64.
Prevention of Relapse in MDD: An Investigation of the Neural Basis of
Self-Regulation of Emotion
Merida M. Grant*, Steven D. Hollon, Richard C. Shelton, Elizabeth
Stringer
65.
What Is the “Therapeutic Window” of Risperidone Long-Acting Injectable
(RLAI)? A Meta-Analysis of Published and Unpublished Data
Gerhard Grunder*, Erik Mannaert, Dean F. Wong, Rossella Medori
66.
MAOA Polymorphism Affects BOLD Responses During Behavioral and
Emotional Regulation
Mary Heitzeg*, Zucker A. Robert, Elzbieta Sliwerska, Margit
Burmeister, Jon-Kar Zubieta
119
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67.
Brain Glycine Increases Detected During Oral Glycine Supplementation
with TE-Averaged Proton Spectroscopy
Marc J. Kaufman*, Andrew P. Prescot, Dost Ongur, A. Eden Evins,
Tanya Barros, Julie Covell, Liqun Wang, John Brown, Maurizio Fava,
Perry F. Renshaw
68.
DTI of Cerebellar and Basal Ganglia Pathways in OCD
Yijun Liu*, Wayne K. Goodman
69.
The Old Drug Scopolamine Offers New Promise as a Potent
Antidepressant Agent: A Randomized, Placebo-Controlled Clinical Trial
Maura L. Furey*, Wayne C. Drevets
70.
Genetic Analysis of Dorsal Raphe Tph2 Expression: Potential Interaction
with Antidepressant Responsive Gene Kf1 (Rnf103)
Steven J. Garlow*, Ericka Boone, Wei Li
71.
Genetic Analysis of Dorsal Raphe 5-HT1A, SERT and Glucocorticoid
Receptor Expression: Potential Shared Genetic Regulation
Ericka Boone, Wei Li, Steven J. Garlow*
72.
Glucocorticoid Receptor Transgenic Mice as Models for Depression
Peter Gass*, Sabine Chourbaji, Stephanie Ridder, Rainer Hellweg,
Alexandre Urani, Christiane Zacher, Wolfgang Schmid, Mathias Zink,
Heide Hortnagl, Herta Flor, Gunther Schutz, Fritz A. Henn
73.
Integration of Emotion-Laden and Working Memory-Related Information
in the Prefrontal Cortex
Aaron L. Goldman*, Lukas Pezawas, Gang Chen, Andreas MeyerLindenberg, Terry E. Goldberg, Ziad S. Saad, Venkata S. Mattay,
74.
Neural Correlates of Anxiety in Serotonin 1A Receptor-Deficient Mice
Joshua A. Gordon*, Clay O. Lacefield, Clifford G. Kentros, Rene Hen
120
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75.
Mouse Strain Differences in Single Dose Lithium Attenuation of
Amphetamine Hyperactivity
Todd D. Gould*, Alyssa M. Picchini, Kelley C. O’Donnell, Robert J.
Schloesser, Husseini K. Manji
76.
Prevalence of Metabolic Syndrome in Partial Responders to Selective
Serotonin Reuptake Inhibitors with Major Depressive Disorder
Tracy L. Greer*, Madhukar H. Trivedi, Timothy S. Church, Bruce D.
Grannemann, Daniel I. Galper, Prabha Sunderajan
77.
Surinabant, a New CB1 Receptor Antagonist, Displays Efficacy in Animal
Models of Attention Deficit/Hyperactivity Disorder
Caroline Louis, Jean-Paul Terranova, Michel Decobert, Jean-Charles
Bizot, Dominique Francon, Craig Karson, Richard Alonso, Caroline
Cohen, Guy Griebel*
78.
The Dexamethasone/CRF Test in Men with Major Depression: Role of
Childhood Trauma
Christine Heim*, Tanja Mletzko, David Purselle, Dominique L.
Musselman, Charles B. Nemeroff
79.
Regulation of 5-HT1A Receptor Function in Inducible BDNF Knock-Out
Mice Following Administration of Fluoxetine or Corticosterone
Julie G. Hensler*, Lisa M. Monteggia
80.
Demonstration on PET of a Widespread Deficiency in Serotonin
Transporter Binding in Bipolar Depression
Maria A. Oquendo, Ramin S. Hastings, Yung-yu Huang, Norman
Simpson, R Todd Ogden, Ronald L. Van Heertum, J John Mann*,
Ramin V. Parsey
81.
Anxiolytic-Like Effects of a DNA Enzyme Targeting the CorticotropinReleasing Factor 2(a) Receptor (CRF2(a)) in the Rat Lateral Septum
Steve A. Nanda, Ned H. Kalin*, Dimitri E. Grigoriadis, Patrick H.
Roseboom
121
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82.
A Randomized Placebo-Controlled Trial of Risperidone Augmentation for
Patients with Difficult-to-Treat Unipolar, Nonpsychotic Major Depression
G I. Keitner*, P T. Ninan, C E. Ryan, S Garlow, D A. Solomon, C B.
Nemeroff, M B. Keller
83.
Placebo-Controlled Trial of Venlafaxine ER in Prevention of Recurrence in
Patients with Recurrent Unipolar Major Depression
Martin B. Keller*, Bing Yan, Saeed Ahmed, Erika Parker-Zavod, Ron
Pedersen
84.
Rapid Cycling Differentially Exacerbates Bipolar II Compared to Bipolar I
Disorder: Implications for Adjunctive Antidepressant Therapy
Terence A. Ketter*, Joseph Calabrese, Charles Bowden, Lauren
Marangell, Laszlo Gyulai, Andrew Nierenberg, Stephen Wisniewski,
Gary Sachs
85.
The REVAMP Medication Algorithm for Chronic Depression: Preliminary
Results
James H. Kocsis*, Martin B. Keller, Daniel N. Klein, Philip T. Ninan,
Alan F. Schatzberg, Michael E. Thase, Madhukar H. Trivedi, Steven
Wisniewski, Alan J. Gelenberg
86.
Olanzapine in the Treatment of Acute Mania in Adolescents with Bipolar I
Disorder: A 3-Week Randomized Double-Blind Placebo-Controlled Study
Mauricio Tohen, Ludmila Kryzhanovskaya, Gabrielle Carlson, Melissa
DelBello, Janet Wozniak, Robert Kowatch*, Karen Wagner, Robert
Findling, Daniel Lin, Carol Robertson-Plouch, Wen Xu, Xiaohong
Huang, Ralf Dittman, Joe Biederman
87.
Paroxetine-Induced Increase in LDL Cholesterol Levels
Jean-Michel Le Melledo*, Kevin Mailo, Maria Castillo Abadia, Lucas
Gil, Nathalie Lara, Stephen Newman, Glen Baker, Stephen Archer,
Mickael Van Ameringen
88.
Reduced Brain Docosahexaenoic Acid Content After a Single
Reproductive Cycle in Female Rats Maintained on a Diet Deficient in n-3
Polyunsaturated Fatty Acids
Beth Levant*, Jeffery D. Radel, Susan E. Carlson
122
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89.
Pooled Analysis of Response and Remission Rates with Venlafaxine ER in
Social Anxiety Disorder
Michael Liebowitz*, Jonathan R. Davidson, Carlos Blanco, Raj
Tummala, Qin Jiang
90.
Randomized Controlled Trial of the Cognitive Side Effects of Magnetic
Seizure Therapy and Electroconvulsive Shock
Sarah H. Lisanby*, Tammy D. Moscrip, Bruce Luber, Matthew
Truesdale, Niko Reyes, Louis Trotman, Herbert S. Terrace
91.
The Familial Aggregation Anxiety Disorders Ascertained from the
Community versus Clinics
Nancy C. Low*, Lihong Cui, Kathleen R. Merikangas
92.
Increased Neurogenesis in CREB-Deficient Mice is Associated with
Antidepressant-Like Behavior
Jessica E. Malberg*, Alana C. C. Conti, Anita J. Bescholt, Irwin
Lucki, Julie A. Blendy
93.
Lithium Increases Gray Matter in the Prefrontal and Subgenual Prefrontal
Cortices in Treatment Responsive Bipolar Disorder Patients
Gregory J. Moore, Bernadette M. Cortese, Debra A. Glitz, Caroline
Zajac-Benitez, Jorge A. Quiroz, Thomas W. Uhde, Wayne C. Drevets,
Husseini Manji*
94.
Vagus Nerve Stimulation for the Treatment of Rapid Cycling Bipolar
Disorder
Lauren Marangell*, Trisha Suppes, Holly Zboyan, Grace Fischer,
James Martinez, Diane Snow, Suresh Sureddi
95.
A Randomized, Double-Blind, Placebo-Controlled, Flexible-Dose, Trial of
Augmentation with OROS Methylphenidate in Treatment Resistant
Depression
Prakash S. Masand*, Ashwin A. Patkar, Kathleen Peindl, Christa
Hooper-Wood, Patrick E. Ciccone, Daniel Blazer
123
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96.
A Genome-by-Genome Interaction Linkage Scan of Bipolar Disorder
Melvin McInnis*, Peter Zandi, Anjene Addington, Carl Langefeld,
John Nurnberger, Bill Byerley, Elliot Gershon, John Kelsoe, John
Rice, Bill Scheftner, Bill Coryell, Wade Berrettini, Francis McMahon
97.
Behavioral and Anatomical Interactions Between Dopamine and
Corticotropin-Releasing Factor (CRF)
Edward G. Meloni*, Lyle P. Gerety, Allison T. Knoll, Bruce M.
Cohen, William A. Carlezon
98.
Amyloid PET Imaging with Pittsburgh Compound-B in Late Life
Depression with Cognitive Impairment
Carolyn C. Meltzer*, Meryl A. Butters, William E. Klunk, Chester A.
Mathis, Julie C. Price, Brian J. Lopresti, Scott K. Ziolko, Jessica A.
Hoge, Charles F. Reynolds, Steven T. DeKosky
99.
Familial Patterns of Comorbidity of Migraine and Affective Disorders
Kathleen R. Merikangas*, Nancy C. Low, Lihong Cui
100.
Emergence of Anhedonia in Laboratory Rats During Continuous
Subordination Stress: Relevance to Antidepressants and Stimulant Abuse
Klaus A. Miczek*, Herbert E. Covington, Artur K. Kieres, Jasmine J.
Yap, Ella M. Nikulina
101.
The Anxiolytic Opipramol Affects Calcium Signalling via Sigma
Receptors
Walter E. Muller*, Bettina Henke, Kristina Treiber
102.
Antidepressant Prescribing Trends Pre and Post-Black Box Warning: A
Review of the Medicaid Database
Meera Narasimhan*, Richard Rech, Richard Harding
103.
Cognitive Function in Patients with Resistant Depression: Effects of
Antidepressant Monotherapy and Risperidone Augmentation
Philip D. Harvey, Robert Bilder, Georges M. Gharabawi, Carla M.
Canuso, Gahan J. Pandina, Ibrahim Turkoz, Charles Nemeroff*
124
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104.
Alterations of Cortico-Limbic Responsiveness to Emotional Valenced
Stimuli in Alpha2CDel322-325 Carriers with Depression and Controls
Alexander Neumeister*, Wayne C. Drevets, David Luckenbaugh,
David Goldman, Inna Belfer, Peter Herscovitch, Dennis S. Charney
105.
Fluoxetine and Triiodothyronine Reduce 5-HT1A and 5-HT1B Receptor
Activites and mRNA Levels in Male but Not in Female Rats
Michael E. Newman*, Ronen Segman, Tsuri Lifschytz, Galit Shalom,
Tanya Golzer, Eitan Gur, Bernard Lerer
106.
Sleep EEG Response to Metyrapone May be a Measure of Hypothalamic
CRF Activity: A Study of Women with and Without Posttraumatic Stress
Disorder
Thomas Neylan*, Christian Otte, Rachel Yehuda, Charles Marmar
107.
CSF 5-HIAA, Suicide Intent and Hopelessness in the Prediction of Suicide
in High Risk Suicide Attempters
Peter Nordstrom*, Jussi Jokinen, Mats Samuelsson, Anna-Lena
Nordstrom, Marie Asberg
108.
Association of the Down-Regulation of the Norepinephrine Transporter in
Rat Brain with the Persistent Behavioral Effects Observed Following
Repeated Treatment with Desipramine
James M. O’Donnell*, Alicia M. Crissman, Zaorui Zhao
109.
Transmission of Mood Disorders to the Offspring of Parents with Bipolar
Disorder and Major Depressive Disorder
Maria A. Oquendo*, Boris Birmaher, Adrienne Tin, Jamie Zelazny,
Barbara H. Stanley, Nadine Melhem, Laurence Greenhill, Steven P.
Ellis, David Kolko, Beth S. Brodsky, J. John Mann, David A. Brent
110.
Brain Derived Neurotrophic Factor (BDNF) is Decreased in Platelets and
Lymphocytes of Pediatric Patients with Bipolar Disorder
Ghanshyam N. Pandey*, Yogesh Dwivedi, Hooriyah S. Rizavi, Xinguo
Ren, Amal C. Mondal, Mani Pavuluri
125
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111.
Resolution of Sleepiness and Fatigue in the Treatment of Major Depressive
Disorder: A Comparison of Bupropion and the Selective Serotonin
Reuptake Inhibitors
George I. Papakostas*, David J. Nutt, Vivan L. Tucker, Alok Krishen,
Maurizio Fava
112.
Proton Magnetic Resonance Spectroscopy Study of the Effects of Lithium
on Myo-Inositol in Bipolar Depressed Adolescents
Nick C. Patel*, Melissa P. DelBello, Kim M. Cecil, Holly S. Bryan,
Caleb M. Adler, Kevin E. Stanford, Stephen M. Strakowski
113.
Electroconvulsive Seizures Increase Cell Proliferation in the Adult Monkey
Cortex
Tarique D. Perera*, Michael Persky, Michele Insanally, Alexander
Sackeim, Jeremy Coplan, Andrew Dwork, Harold Sacheim
114.
Pharmacological Characterization of the Novel 5-HT2C Agonist SCA-136:
Antidepressant-Like Effects
Sharon Rosenzweig-Lipson*, Jack Bergman, John Dunlop, Karen
Marquis, Jean Zhang, Siva Ramamoorthy, Jessica Malberg, Claudine
Pulicicchio, Hossein Mazandarani, Steve Grauer, Paul J. Mitchell,
Boyd Harrison, Menelas N. Pangalos, Lee Schechter, Gary Stack
115.
Constitutive Activation of the G-Protein Subunit G αs Causes Behavioral
and Biochemical Deficits Due to a PKA-Dependent Upregulation of PDE
Activity
Michele Kelly, Michael Esposito, Jan Tokarczyk, Steve Siegel, Steve
Kanes, Ted Abel*
116.
Does Maintenance Treatment with Atypical Antipsychotics Worsen Quality
of Life Among Stable Patients with Schizophrenia?
Charles M. Beasley, Jr.*, Virginia K. Sutton, Cindy Taylor, Gopalan
Sethuraman, Martin Dossenbach, Dieter Naber, David Pickar
117.
Dopaminergic Modulation of Excitatory and Inhibitory Transmission in the
Basolateral Amygdala-Prefrontal Cortex Pathway
Stan B. Floresco*, Maric T. Tse
126
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118.
Schizophrenia, Diabetic Ketoacidosis and Atypical Antipsychotic Agents
David C. Henderson*, Enrico Cagliero, Paul M. Copeland, Pearl M.
Louie, Christina P. Borba, Donald C. Goff
119.
DISC1 Polymorphism in Schizophrenia: Associations with Cognition and
MRI Brain Morphology
Beng-Choon Ho*, Thomas H. Wassink
120.
Temporal and Prefrontal Cortex Gray Matter Abnormalities in Patients
with Schizophrenia and Their Unaffected Siblings; An Optimized VoxelBased Morphometry Study
Robyn A. Honea*, Andreas Meyer-Lindenburg, Katherine Hobbs,
Lukas Pezawas, Beth A. Verchinski, Aaron L. Goldman, Venkata S.
Mattay, Daniel R. Weinberger, Joseph H. Callicott
121.
Identification of a Novel Genetic Locus at 7q36.1 in Strong LD with
Schizophrenia and the Differential Expression of the Flanking Genes,
NOS3 and KCNH2
Stephen J. Huffaker*, Daniel R. Weinberger
122.
Allelic Variations in NRG1 Affect Region-Specific Expression of Low
Affinity Nicotinic Acetylcholine Receptors in the Human Brain
Thomas M. Hyde*, Shiny V. Mathew, Barbara K. Lipska, Shruti N.
Mitkus, Radhakrishna Vakkalanka, Richard E. Straub, Daniel R.
Weinberger, Joel E. Kleinman
123.
Treatment of Patients with Acute Schizophrenia Using Paliperidone
Extended-Release Tablets: A 6-Week Placebo-Controlled Study
John M. Kane*, Michelle Kramer, Lisa Ford, Christiana GassmannMayer, Pilar Lim, Marielle Eerdekens
124.
A Comparison of the Effects of Olanzapine, Quetiapine, and Risperidone
on Neurocognitive Function in First-Episode Psychosis
Richard Keefe*, Hongbin Gu, Diana Perkins, Joseph McEvoy, Robert
Hamer, Jeffrey Lieberman
127
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125.
Relationship of Paternal Age to N-Acetyl-Aspartate in the Prefrontal
Cortex in Schizophrenia
Lawrence S. Kegeles*, Dikoma C. Shungu, Xiangling Mao, Raymond
Goetz, Charles B. Mikell, Anissa Abi-Dargham, Marc Laruelle,
Dolores Malaspina
126.
Cardiac-Related Mortality in People with Schizophrenia
Deanna L. Kelly*, Robert R. Conley, Robert P. McMahon, Raymond
C. Love, Yang Yu, Tara Wagner
127.
Cognitive Remediation and Social Cognition in Early Schizophrenia:
Preliminary fMRI Data
Matcheri S. Keshavan*, Vaibhav A. Diwadkar, Jeffrey J. Nutche,
Gerald E. Hogarty
128.
Factorial Structure of the Schedule for Deficit Syndrome in Schizophrenia
David Kimhy*, Scott Yale, Raymond R. Goetz, Lynn Marcinko
McFarr, Cheryl Corcoran, Dolores Malaspina
129.
Association of Depressive Symptoms and Discontinuation from
Schizophrenia Treatment: A Post-hoc Pooled Analysis of 4 Controlled
Atypical Antipsychotic Treatment Trials
Adam Meyers, David Adams, Haya Ascher-Svanum, Richard Mohs,
Bruce Kinon*
130.
Increased Brain Activation During Eye Gaze Discrimination in
Schizophrenia
Christian G. Kohler*, James Loughead, Kosha Ruparel, Tim
Indersmitten, Ruben C. Gur
131.
Abnormal Expression of NMDA Receptor Subunits and Interacting PSD
Molecules in the Endoplasmic Reticulum in Schizophrenia
Lars V. Kristiansen*, Vahram Haroutunian, James H. MeadorWoodruff
128
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132.
Functional Effects of Haloperidol and Olanzapine over a 6-Week
Treatment Period: Relation to Clinical Response
Adrienne C. Lahti*, Henry H. Holcomb, Carol A. Tamminga, Martin
A. Weiler
133.
Prefrontal Cortical“UP” States in Adult Rat Brain Slice: Role of Glutamate
Spillover and 5-HT2A Receptors
Evelyn K. Lambe*, George K. Aghajanian
134.
Schizophrenia is Associated with Increased Synaptic Dopamine in
Associative Rather than Limbic Regions of the Striatum
Marc Laruelle*, Lawrence S. Kegeles, Gordon W. Frankle, Raj
Narendran, Roberto Gil, Peter S. Talbot, Dah-Ren Hwang, Yiyun
Huang, Thomas Cooper, Slifstein Mark, Anissa Abi-Dargham
135.
DRD2 Promoter Region Variation Predicts Sustained Response to
Antipsychotic Medication in First Episode Schizophrenia
Todd Lencz*, Delbert G. Robinson, Ke Xu, Jenny Ekholm, Serge
Sevy, Handan Gunduz-Bruce, Margaret G. Woerner, John M. Kane,
David Goldman, Anil K. Malhotra
136.
Clozapine Effects on Memory Function are Reversed by Hippocampal
Damage
Edward D. Levin*
137.
Synergetic Effects of Quetiapine and Venlafaxine in Preventing the
Decrease in Cell Proliferation and BDNF Expression in Rat Hippocampus
Caused by Chronic Restraint Stress
Xin-Min Li*, Haiyun Xu
138.
Remission in Schizophrenia: A Comparison of 2 Dose Regimens of
Ziprasidone versus Haloperidol Treatment in a 3-Year Double-Blind
Extension Study
Jeffrey Lieberman*, Lewis Warrington, Antony Loebel, Cynthia Siu
139.
Probing the Cognitive, Clinical, and Functional Impairments of
Schizophrenia Patients with Mismatch Negativity
Gregory A. Light*, Katrin Meyer-Gomes, Joyce Sprock, David L.
Braff
129
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140.
Role of Catechol-O-Methyltransferase Val/Met Polymorphism on P50
Sensory Gating in Schizophrenia
Brett Y. Lu*, Kimberly Martin, Ashley K. Smith, Stephen F. Lewis,
Gregory A. Miller, Jose M. Canive
141.
The Prospective Study of Cannabis Use, Symptoms and Functioning in
Patients Prodromal to Psychosis
Cheryl Corcoran, David Kimhy, Yadira Sanchez, Jessica MacDonald,
Herbert Kleber, Dolores Malaspina*
142.
Symptomatic Remission in Schizophrenia Patients Treated with
Aripiprazole or Haloperidol for up to 52 Weeks
Anil Malhotra*, John Kane, David Crandall, Xiaoling Wu, William
Carson, Dan Oren, Dusan Kostic, Wim Swyzen
143.
Inhibition of the Glycine Transporter (GlyT1) Potentiates the Effect of
Risperidone, but Not Clozapine, on Glutamatergic Transmission in the Rat
Medial Prefrontal Cortex
Monica M. Marcus*, Asa Konradsson, Peter Hertel, Torgny H.
Svensson, Kent E. Jardemark
144.
Efficacy and Tolerability of Two Fixed Dosages of Paliperidone ExtendedRelease Tablets in the Treatment of Acute Schizophrenia: A 6-Week
Placebo-Controlled Study
Stephen R. Marder*, Michelle Kramer, Lisa Ford, Els Eerdekens, Lim
Pilar, Marielle Eerdekens
145.
ERP P300 and Mismatch Negativity Abnormalities in Prodromal and Early
Illness Schizophrenia: Predicting Conversion to Psychosis
Daniel H. Mathalon*, Thomas H. McGlashan, Tandy J. Miller, Scott
W. Woods
146.
Comparison of Atypicals in First-Episode Psychosis (CAFE): A
Randomized, 52-Week Comparison of Olanzapine, Quetiapine, and
Risperidone
Joseph P. McEvoy*, Joseph A. Lieberman, Diana Perkins, Robert M.
Hamer
130
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147.
Novel Targets of Quaking: A Gene Essential for Myelination That is
Severely Reduced in Schizophrenia
Lynne A. McInnes*, Sean Ryder
148.
Comparison of Clozapine and High Dose Olanzapine in Treatment
Resistant Schizophrenia in a Double Blind, Randomized, 6 Month Clinical
Trial
Karu Jayathilake, David O. Meltzer*, Joyce Small, Herbert Y. Meltzer
149.
Comparative Effects of Ziprasidone and Olanzapine on Markers of Insulin
Resistance: Results of a 6-Week Randomized Study in Patients with Acute
Schizophrenia
Jonathan Meyer*, Antony Loebel, Henry Nasrallah
150.
Aripiprazole Effects on Highly Agitated Patients with Alzheimers’s Disease
and Associated Psychosis
Jacobo Mintzer*, Lindsay DeVane, Britt West, Joseph Pultz, Andrei
Pikalov, Ronald Marcus, Rolando Gutierrez-Esteinou, David Crandall
151.
A New Approach to Assessing Objective Functional Outcomes in
Schizophrenia: A Validation Study
Richard Mohs*, S Dube, L Bowman, B Kinon, L. Kleinman, L. Frank,
D Revicki, Y Zhao
152.
Error Feedback Negativity During a Learning Task in Schizophrenia
Sarah E. Morris*, Erin A. Heerey, Benjamin M. Robinson, James M.
Gold
153.
Prefrontal Activity in Schizophrenia: An Interleaved TMS/fMRI Study
Ziad Nahas*, Chris Molnar, Dave Ramsey, John Walker, Jejo Koola,
Kevin Johnson, Richard Holt, Michael Horner, Frank A. Kozel,
Stewart Denslow, Daryl Bohning, Mark S. George
154.
Low Rates of Treatment for Metabolic Disorders in the CATIE
Schizophrenia Trial at Baseline
Henry A. Nasrallah*
131
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155.
An Integrative Approach to Investigate Molecular Mechanisms Underlying
Schizophrenia Using both Rat and Drosophila Melanogaster
Charles Nichols*, Elaine Sanders-Bush
156.
Association of the 5HT2C Gene Polymorphism and Antipsychotic-Induced
Weight Gain
Charles Nnadi*, Christoph U. Correll, Katherine E. Burdick, Jenny M.
Ekholm, John M. Kane, Anil K. Malhotra
157.
Genetic Analysis Supports a Primary Abnormality in Oligodendrocyte
Function in Schizophrenia
Michael O’Donovan*, Lyudmila Georgieva, George Kirov, Vahram
Haroutunian, Kenneth L. Davis, Joseph D. Buxbaum, Michael Owen
158.
The Consortium on the Gentics of Schizophrenia (COGS): The P50
Auditory Evoked Potential as an Endophenotype in a Large Multi-Site
Study
Ann Olincy*, Jamey Ellis, Robert Freedman
159.
Learning to Relax with MRS: Altered NAA T2 Relaxation Times in
Schizophrenia
David P. Olson*, Joseph Coyle, Yong Ke, Staci A. Gruber, Isabelle
Rosso, Marisa Silveri, Perry F. Renshaw, Deborah A. Yurgelun-Todd
160.
Sleep Spindle Abnormalities in Schizophrenia
Michael J. Peterson*, Fabio Ferrarelli, Reto Huber, Marcello
Massimini, Steve K. Esser, Adam Watson, Giulio Tononi
161.
A Double-Blind Placebo Controlled Trial of Modafinil for Negative
Symptoms in Schizophrenia
Joseph M. Pierre*, John H. Peloian, Donna A. Wirshing, William C.
Wirshing, Stephen R. Marder
162.
PCP- and Cocaine- Induced Changes in White Matter- Comparison with
DTI Findings in Schizophrenia and Cocaine Dependence
Jay Nierenberg*, David G. Guilfoyle, Matthew J. Hoptman, Daniel C.
Javitt
132
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163.
A Post-Marketing Observational Study of the Effects of Donepezil on
Patients with Alzheimer Disease
Jared R. Tinklenberg*, Helena C. Kraemer, Kristine Yaffe, Leslie
Ross, J W. Ashford, Javaid Sheikh, Jerome A. Yesavage, Joy L. Taylor
164.
Alterations in Sensorimotor Processing in Mice with Hyperdopaminergic
or Hypomonoaminergic Tone
William C. Wetsel*, Ramona M. Rodriguiz, Marc G. Caron
165.
Candidate Gene Polymorphisms and Birth Weight (BW) in the National
Longitudinal Study of Adolescent Health (Add Health)
Redford Williams*, Melanie Kail, Marcy Speer, Beverly Brummett,
Stephan Zuchner, Ilene Siegler, John Barefoot, Geeta Swamy,
Haywood Brown, Marie L. Miranda, Allison Ashley-Koch
133
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Poster Session III—Wednesday
1.
Design, Synthesis and Application of Novel Tropane-Based Photoaffinity
Labels Toward the Identification of Binding Domains on the Dopamine
Transporter
Amy H. Newman*, Mu-Fa Zou, Jianjing Cao, Joo H. Cha, John R.
Lever, Theresa Kopajtic, Jonathan L. Katz, M. L. Parnas, Roxanne
Vaughan
2.
White Matter Changes in Cocaine Dependence
Jay Nierenberg*, Laurie Nash, Matthew J. Hoptman, Jan Hrabe, Babak
A. Ardekani, Gregory Bunt, Kelvin O. Lim, John Rotrosen
3.
Prediction of Alcohol Problems Using A Prospective Longitudinal Design
Including Genotype
John I. Nurnberger*, R Wiegand, L Bierut, K Bucholz, T Foroud, H
Edenberg, E T. Meyer, J Kramer, D Dick, W Reich, S Kuperman, V
Hesselbrock, A Goate, B Porjesz, H Begleiter
4.
Casein Kinase 1 Epsilon Modulates Sensitivity to Stimulant Drugs in Both
Mice and Humans: A Translational Genetic Study
Abraham A. Palmer*, Jeremy Veenstra-Vander Weele, Miguel
Verbitsky, Rathi Suresh, Asfia Qaadir, Helen M. Kamens, John K.
Belknap, T C. Gilliam, Edwin H. Cook, Tamara J. Phillips, Harriet De
Wit
5.
Cerebellar Vermis Participation in Cocaine-Related Behaviors
Carl M. Anderson, Luis C. Maas, Blaise D. Frederick, Jacob T.
Bendor, Thomas J. Spencer, Eli Livni, Scott E. Lukas, Alan J.
Fischman, Bertha K. Madras, Perry F. Renshaw*, Marc J. Kaufman
6.
Dysregulation of the Hypothalamic-Pituitary-Adrenal Axis in AlcoholDependent Self-Administering Rats
Heather Richardson*, Laura E. O’Dell, Soon Y. Lee, George F. Koob,
Catherine L. Rivier
134
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7.
Sensitization-Prone C57BL/6J Mice Exhibit Reduced Dopamine D3
Receptor-Mediated Inhibition Relative to Sensitization-Resistant DBA/2J
Mice
Robert K. McNamara, Beth Levant, Benjamin Taylor, Rebecca
Ahlbrand, Amy Liu, Kevin Stanford, Neil M. Richtand*
8.
Rats Maintain Ethanol Self-Administration into the Posterior Ventral
Tegmental Area (VTA) Despite the Aversive Effects of Bicuculline
Zachary A. Rodd*, Scott M. Oster, Jamie E. Toalston, James M.
Murphy, Richard L. Bell, Ting-Kai Li, William J. McBride
9.
Exposure to Cues Associated with Palatable Food Increases ImmediateEarly Gene (IEG) mRNA and Proenkephalin (PENK) premRNA
Expression in the Rat Brain
Craig A. Schiltz*, Ann E. Kelley, Charles F. Landry
10.
Ontogeny of the HPA-Axis and Monoamine Response to Acute Ethanol
Challenge in Male and Female Adolescent Rhesus Macaques
Melanie L. Schwandt*, Christina S. Barr, Stephen J. Suomi, James D.
Higley
11.
Aripiprazole Attenuates Cocaine-Seeking Behavior in an Animal Model of
Relapse
Ronald E. See*, Matthew W. Feltenstein, C. A. Altar
12.
Chronic, but Not Acute, Desipramine Treatment Prevented Nicotine
Withdrawal and Decreased Nicotine Self-Administration in Rats
Svetlana Semenova*, Neil E. Paterson, Athina Markou
13.
Positron Emission Tomographic Study of Regional Brain Metabolic
Responses to a Serotonergic Challenge in Major Depressive Disorder with
and Without Comorbid Alcohol Dependence
Leo Sher*, Matthew S. Milak, Ramin V. Parsey, Thomas B. Cooper,
Juan J. Carballo, Maria A. Oquendo, J J. Mann
14.
NMDA Receptors Mediate Some of the Lingering Behavioral Deficits of
Repeated Ethanol Exposure in Adolescent Rats
Ratna Sircar*
135
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15.
Selective Enhancement of Limited Access Ethanol Intake in IsolateHoused Alcohol-Preferring (P) Rats
Craig J. Slawecki*, Cindy L. Ehlers
16.
Amphetamine Effects on Amygdala Responses to Affective Pictures in
Healthy Volunteers
Tara L. White, Robert M. Swift*, Ronald A. Cohen, Lawrence H.
Sweet
17.
The Effects of MDMA (Ecstasy) on Sleep Architecture and Mood in
Humans
Manuel E. Tancer*, Timothy Roehrs, Chris-Ellyn Johanson
18.
Positive and Negative Transcription Regulation of NR2B Gene in Basal
and Ethanol-Induced Gene Expression in Fetal Cortical Neurons
Maharaj K. Ticku*, Mei Qiang
19.
An Open Label Pilot Trial of Atomoxetine and Four-Session Motivational
Interviewing for Cannabis Dependence
Carlos F. Tirado*, Nathalie Maullin, Kampman Kyle, Lauren Klein,
Charles O’Brien
20.
Brain Stimulation Reward Thresholds Are Altered by Viral VectorMediated Elevations of GluR Subunits Within the Nucleus Accumbens
Shell
Mark S. Todtenkopf*, Rachael L. Neve, William A. Carlezon
21.
The Impact of Screening, Brief Intervention, and Referral to Treatment
(SBIRT) on Emergency Department(ED) Patients’ Alcohol Use
Kimberly Walton*, Research Collaborative The Academic ED SBIRT,
Robert E. Taylor
22.
Effects of Acute Plasma Tryptophan Depletion on Serotonin Receptor
Binding Using PET in Healthy Controls: Implications for Alcoholic Brain
Disease
Wendol A. Williams*, Richard E. Carson, Andreas Heinz, James
Bjork, Mary-Anne Enoch, Christopher Geyer, Robert Rawlings,
Daniel Hommer, David Goldman, Peter Herscovitch
136
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23.
Baseline Data from CTN Study 0010: Buprenorphine/Naloxone Facilitated
Psychosocial Treatment for Opioid Dependent Adolescents/Young Adults
George E. Woody*, Sabrina Poole, Forman Robert, Blaine Jack
24.
A Large-Scale Approach for Identifying Vulnerability Genes to
Alcoholism: A 1536 SNP Chip
Ke Xu*, Qiaoping Yuan, Colin A Hodgkinson, Pei-Hong Shen, Lisa
Neuhold, Zhaoxia Ren, Kenneth Warren, David Goldman
25.
Nicotinic Agonists Inhibit Reinstatement of Methamphetamine-Seeking
Behavior in Rats
Tsuneyuki Yamamoto*, Takato Hiranita, Kusnandar Anggadiredja
26.
Diffusion Tensor Imaging Measures Correlate with Cognitive Performance
in Heavy Cannabis Smokers
Staci A. Gruber, Deborah A. Yurgelun-Todd*
27.
Region and Emotion Specific Effects of Lorazepam on Neural Responses
to Facial Displays of Affect
K. Luan Phan*, Mike Angstadt, Daniel A. Fitzgerald, Pradeep J.
Nathan, Royce Lee, Emil F. Coccaro
28.
Reproducibility of Proton Spectroscopic Imaging (H1-MRSI) at 3Tesla:
Effects of Corrections for B1 Field and Partial Volume
Stefano Marenco*, Douglas W. Jones, Alan S. Barnett, Jan Willem
Van der Veen, Aronica Cotton, Daniel R. Weinberger
29.
Neuroticism, Extraversion and Alexithymia Are Associated with
Differential Neural Activation Patterns to Emotional Stimuli
Jennifer C. Britton, Brian Martis*, Shao-Hsuan Ho, Stephan F. Taylor,
Israel Liberzon
30.
Magnetic Resonance Spectroscopic Imaging Twenty Years After the
Emergence of Adolescent-Onset Major Depressive Disorder
Sanjay J. Mathew*, Dikoma C. Shungu, Xiangling S. Mao, Heidi
Fitterling, Jonathan M. Amiel, Eric L. Smith, Adriana Feder, Jeremy
D. Coplan, Myrna M. Weissman
137
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31.
COMT val158met Polymorphism Impacts on Reactivity of Amygdala to
Emotion Laden Stimuli
Venkata S. Mattay*, Giuseppe Blasi, Guilna Alce, Saumitra Das,
Joseph H. Callicott, Bhaskar S. Kolachana, Michael F. Egan, Fabio
Sambataro, Andreas Meyer-Lindenberg, Ahmad R. Hariri, Daniel R.
Weinberger
32.
Irritable Bowel Syndrome and Increased Anxiety in Healthy Females, but
Not in Healthy Males, is Associated with Increased Size of a Midbrain
Region Activated During Inescapable Pain
Steven M. Berman, Joshua Bueller, Brandall Suyenobu, Edythe
London, Lin Chang, Bruce D. Naliboff, Emeran A. Mayer*
33.
Increased Basal Ganglia Activity During Interferon-Alpha Therapy for
Malignant Melanoma: Relationship with Neurovegetative Symptoms
Lucile Capuron, Giuseppe Pagnoni, Marina Demitrashvili, David H.
Lawson, Gregory S. Berns, Charles B. Nemeroff, Andrew H. Miller*
34.
Distribution of [11C]PIB in a Nondemented Population: Implication for
Use as an Antecedent Marker of Alzheimer’s Disease
Mark A. Mintun*, Gina N. LaRossa, Yvette I. Sheline, Sang Y. Lee,
Carmen S. Dence, Mach H. Robert, William E. Klunk, Chester A.
Mathis, Steven T. DeKosky, John C. Morris
35.
Positron Emission Tomography of Brain 5HT1A Receptor Binding with
[11-C]WAY100635 in Postpartum Depressed and Nondepressed Women
Eydie L. Moses-Kolko*, Katherine L. Wisner, Julie C. Price, Sarah L.
Berga, Chester Mathis, Wayne C. Drevets, Andrea L. Confer, Carl
Becker, Carolyn C. Meltzer
36.
The Sensitivity of the Loudness Dependence Auditory Evoked Potential
(LDAEP) as a Measure of Central Serotonin Function in Humans
Pradeep J. Nathan*, Barry O’Neill, Julian Simmons, Nick Allen,
Matthew P. Galloway, K L. Phan, Rodney J. Croft
37.
FDG-PET in Laboratory Induced Aggression in Borderline Personality
Disorder
Antonia S. New*, Roanna Trisdorfer, Erin A. Hazlett, Randall E.
Newmark, Monte S. Buchsbaum, Larry J. Siever
138
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38.
Acute Occupancy of Brain Serotonin Transporter by Sertraline as
Measured by [11C]DASB and Positron Emission Tomography
Ramin V. Parsey*, Justine M. Kent, Maria A. Oquendo, Misty
Richards, Mali Pratap, Thomas Cooper, Victoria Arango, J. J. Mann
39.
Lorazepam Dose-Dependently Decreases Risk-Taking Related Activation
in the Caudate
Martin P. Paulus*, Estibaliz Arce, Murray B. Stein
40.
An fMRI Study of the Interface Between Affective and Cognitive Circuitry
in Pediatric Bipolar Disorder
Mani N. Pavuluri*, Aryal Subhash, Megan M. O’Connor, Erin Harral,
Ellen Herbener, John A. Sweeney
41.
FDG and PIB PET Imaging in Alzheimer’s Disease and Mild Cognitive
Impairment
Julie C. Price*, Scott K. Ziolko, Lisa A. Weissfeld, William E. Klunk,
Brian J. Lopresti, Jessica A. Hoge, Xueling Lu, Wenzhu Bi, Carolyn
C. Meltzer, Nicholas Tsopelas, Steven T. DeKosky, Chester A. Mathis
42.
Imaging Neuroinflammation in Alzheimer Disease with
[111C]Arachidonic Acid and Positron Emission Tomography
Stanley I. Rapoport*, Richard E. Carson, Abesh Bhattacharjee, Mark
B. Schapiro, Giuseppe Esposito, Peter Herscovitch, William C.
Eckelman, Giuseppe Esposito
43.
A Voxel-Based, Whole Brain MRI Analysis of Adolescents with Psychotic
Illnesses
Donald C. Rojas*, David B. Arciniegas, Peter Teale, Olivia Hernandez,
Martin L. Reite
44.
Localization of Increased White Matter Hyperintensities in Late Life
Depression Using an Automated Voxel-Wise Method
Yvette Sheline*, Robert McKinstry, Deanna Barch, Avi Snyder, Asif
Moinuddin, Consuelo Wilkins, Jon Christensen, Mark Mintun
139
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45.
Effects of Lithium Treatment on Human Brain Structure Mapped Using
Longitudinal MRI
Alex D. Leow, Paul M. Thompson, Kiralee M. Hayashi, Carrie
Bearden, Mark A. Nicoletti, Serap E. Monkul, Roberto B. Sassi, Paolo
Brambilla, Alan G. Mallinger, Jair Soares*
46.
Marked Deficits in Membrane Phospholipid Precursor Levels in AttentionDeficit/Hyperactivity Disorder (ADHD) Children with Comorbid
Diagnoses
Jeffrey A. Stanley*, Matcheri S. Keshavan, Heidi Kipp, Erika
Greisenegger, Kanagasabai Panchalingam, Jay W. Pettegrew, Oscar G.
Bukstein
47.
GABRA2 Genetic Variation and Response of the Human Amygdala and
Insula to Fearful Faces
Murray B. Stein*, Martin P. Paulus, Joel Gelernter
48.
Diffusion Tensor Imaging: Fractional Anisotropy in White Matter,
Symptom Severity, and Cognition in the Brains of Schizophrenia Patients
Daniel G. Stewart*, Joseph I. Friedman, Cheuk Tang, Jack Gorman,
Phil Harvey, David Carpenter, Arash Hajianpour, Johnny Ng, Patrick
Hof, Monte Buchsbaum, Kenneth L. Davis
49.
Physiological Correlates of a Non-Working Memory Prefrontal Task
Steven Sust*, Joshua Buckholtz, Brad Zoltick, Doug Jones, Bart
Rypma, Hao Y. Tan, Venkata Mattay, Daniel R. Weinberger, Joseph
Callicott
50.
The Development of Human Parent-Infant Attachment: Functional Brain
Imaging During the Early Postpartum
James E. Swain*, James F. Leckman, Linda C. Mayes, Ruth Feldman,
Robert T. Schultz
51.
Rolling with the Punches: Emotional Resilience and Ventral Prefrontal
Cortex
Stephan Taylor*, Christian E. Waugh, Tor D. Wager, Douglas C. Noll,
Barbara L. Fredrickson
140
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52.
Evidence for Sensitive Periods in the Effects of Childhood Abuse on
Regional Brain Morphology
Martin H. Teicher*, Susan L. Andersen, Akemi Tomoda, Ann Polcari,
Evelyn Vincow, Elizabeth Valente
53.
Allelic Variation of PPP1R1B, Encoding DARPP-32, Affects Human
Striatal Volume and Striatal-Prefrontal Structural Connectivity
Beth A. Verchinski*, Andreas Meyer-Lindenberg, Lukas Pezawas,
Richard Straub, Robyn Honea, Aaron L. Goldman, Katherine Hobbs,
Joshua W. Buckholtz, Joseph H. Callicott, Bhaskar Kolachana,
Venkata S. Mattay, Daniel R. Weinberger
54.
Gastric Stimulation Activates Brain Satiety Circuiy
Gene-Jack Wang*
55.
123I-ADAM SPECT Study in Patients with Major Depression: Serotonin
Transporter Occupancy Induced by Paroxetine and Relationship with
Clinical Response
Victor S. Perez*, Ana Catafau, P Plaza, JC Pascual, S Bullich, M
Danus, D Puigdemont, I Corripio, MM Penengo, J Perich, E Alvarez
56.
Epistasis of SERT & BDNF: A Mechanistic Model of Depression
Lukas Pezawas*, Aaron L. Goldman, Beth A. Verchinski, Venkata S.
Mattay, Gang Chen, Katherine Hobbs, Robyn A. Honea, Joseph S.
Callicott, Bhaskar S. Kolachana, Richard E. Straub, Michael F. Egan,
Andreas Meyer-Lindenberg, Daniel R. Weinberger
57.
Associations in the Longitudinal Course of Body Dysmorphic Disorder
with Major Depression, OCD, and Social Phobia
Katharine A. Phillips*, Robert L. Stout
58.
Toward the Identification of Biological Markers of Bipolar Disorder: A
First Stage Neuroimaging Study
Mary L. Phillips*, Cecile D. Ladouceur, Stefanie Hassel, Natalie Kerr,
Greg Siegle, Kate Fissell, Simon Surguladze, Michael E. Thase, David
J. Kupfer
141
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59.
Shared Genetic Contributions to Pathological Gambling and Major
Depression in Men
Marc N. Potenza*, Hong Xian, Kamini R. Shah, Jeffrey F. Scherrer,
Seth A. Eisen
60.
Adolescent Depression and Neuronal Circuits Associated with Reward
Processes
Uma Rao*, Anup Bidesi, Monique Ernst, Carol Tamminga
61.
Depression-Insulin Resistance Link
Natalie L. Rasgon*, Margaret F. Reynolds, Laurel N. Zappert, Heather
A. Kenna, M.A.
62.
Pediatric Bipolar Disorder and Face Processing: Neural and Behavioral
Deficits
Brendan A. Rich*, Deborah T. Vinton, Lisa Berghorst, Erin B.
McClure, Daniel S. Pine, Ellen Leibenluft
63.
Role of CRF2 Receptors in Maintenance and Recovery from CRF1
Receptor-Induced Alterations in Defensive Startle
Victoria B. Risbrough*, Sarah Coste, Mary Stenzel-Poore, Mark
Geyer
64.
Safety and Tolerability of the Selegiline Transdermal System 20 mg for
Treatment of Major Depression
Donald S. Robinson*, Bryan J. Campbell, Jay D. Amsterdam
65.
Alterations in Human Amygdala Corticotropin-Releasing Factor (CRF)
Receptor Binding Associated with Psychiatric Illness
Patrick H. Roseboom*, Dimitri E. Grigoriadis, Susan K. Sullivan,
Ryan J. Herringa, Ned H. Kalin
66.
A “Pharmacological Stressor” Model of Anxiolysis in Monkeys:
Alprazolam Attenuation of the Behavioral and Physiological Effects of
Yohimbine
Melissa A. Birkett, Donna M. Platt, Stefan Tiefenbacher, James K.
Rowlett*
142
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67.
Adjunctive Topiramate Therapy in Patients Receiving a Mood Stabilizer for
Bipolar I Disorder: A Randomized, Placebo-Controlled Trial
K.N. Roy Chengappa*, Lesley K. Schwarzmann, Joseph F. Hulihan,
Jim Xiang, Norman R. Rosenthal
68.
Is the Association of PTSD and Poor Health Due to a Common Familial or
Genetic Factor?
Peter P. Roy-Byrne*, Carolyn Noonan, Niloo Afari, Dedra Buchwald,
Jack Goldberg
69.
Blockade of Angiotensin II AT1 Receptors Decreases Anxiety and Prevents
the Isolation Stress-Induced Decrease in Cortical CRF1 Receptors and
Benzodiazepine Binding
Juan M. Saavedra*
70.
Antimanic Response to Aripiprazole with High vs. Low Agitation
Gary Sachs*, Jerrold Rosenbaum, Joseph Pultz, Andrei Pikalov,
Christopher Breeder, Dusan Kostic, David Crandall
71.
Paroxetine Treatment of Compulsive Hoarding
Sanjaya Saxena*, Arthur L. Brody, Karron M. Maidment, Lewis R.
Baxter
72.
The Nucleus Accumbens as Target for Deep Brain Stimulation for
Treatment Refractory Depression
Thomas E. Schlaepfer*, Doris Lenartz, Caroline Frick, Volker Sturm
73.
Time Course of Depressive Symptomatology During Vagus Nerve
Stimulation: Comparisons of US and European Results
Caroline Frick, Stephen Brannan, Mustafa Hasdemir, Zeno Stanga,
Markus Kosel, Hans-Ulrich Fisch, Thomas E. Schlaepfer*
74.
Prospective Study of Plasma Stress Hormones in PTSD
Arieh Y. Shalev*, Ronen Segman, Roger K. Pitman, Yair Bannet,
Rachel Yehuda
75.
Risperidone vs. Bupropion Combined with SSRIs in Treatment Resistant
Unipolar Major Depression
Richard C. Shelton*, Stephanie Addington, Vatsal Thakkar
143
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76.
Effects of Chronic Prednisone Therapy on Mood and Memory: A FollowUp Study
E. Sherwood Brown*, Elizabeth Vera, Alan B. Frol, Dixie J. Woolston,
Brandy Johnson
77.
Effect of Two Prednisone Exposures on Mood and Declarative Memory
E. Sherwood Brown*, Laura Beard, Alan B. Frol
78.
In Vivo Effects of Lithium on Synaptic Plasticity and Levels of BDNF and
Phospho-CREB in Hippocampus
Seong Shim*, Michael Hammonds, Joseph Calabrese
79.
Efficacy and Tolerability of Low Doses of Paroxetine CR in Elderly
Outpatients with Major Depression
Ram K. Shrivastava*, Saraswatiben P. Shrivastava, Johanna Landinez,
Cornelius D. Pitts, Desiree M. Schaefer, Alan Lipschitz, Malini
Iyengar
80.
Efficacy of Ziprasidone in Dysphoric Mania: Pooled Analysis of 2 DoubleBlind Studies
Stephen M. Stahl*, Illise Lombardo, Antony Loebel, Francine Mandel
81.
A Single-Blind Prospective Study of Quetiapine for the Treatment of Mood
Disorders in Adolescents Who Are at High Risk for Developing Bipolar
Disorder
Stephen M. Strakowski*, Melissa P. DelBello, Robert Kowatch,
Rachel Whitsel, Cal Adler
82.
Manic Symptoms During Bipolar Depression: Impulsivity and Suicidality
Alan C. Swann*, Joel L. Steinberg, Frederick G. Moeller
83.
Galanin-Evoked Reductions in Serotonergic Neurotransmission in the
Hippocampus and Dorsal Raphe Nucleus Are Attenuated by GAL3
Receptor Antagonists
Chad J. Swanson*, Xuexiang Zhang, Kang Zheng, Zhi-Qing D. Xu,
Tomas Hokfelt, Heidi Chen, Michael J. Konkel, Huailing Zhong, Mary
M. Walker, Thomas P. Blackburn, Theresa A. Branchek, Christophe P.
Gerald, Douglas A. Craig
144
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84.
Decreased Serotonin-1A Receptor Binding in Social Anxiety Disorder
Rupert Lanzenberger, Christoph Spindelegger, Alexander Holik, Key
Mien, Markus Mitterhauser, Wolfgang Wadsak, Nilufar Mossaheb,
Trawat Attarbaschi, Julia Sacher, Nikolas Klein, Kurt Kletter,
Siegfried Kasper, Johannes Tauscher*
85.
Using Symptom Improvement Patterns to Predict Remission in Depressed
Outpatients Treated with Venlafaxine Extended Release (XR) or Selective
Serotonin Reuptake Inhibitors (SSRI)
Madhukar H. Trivedi*, Bruce D. Grannemann, Jeff Musgnung, Qin
Jiang, Raj Tummala, Michael E. Thase
86.
Inhibited Temperament and HPA Axis Function in Healthy Adults
Audrey R. Tyrka*, Linda Carpenter, George Anderson, Lawrence Price
87.
Antidepressant Treatment and Risk of Suicide Attempt by Adults with
Major Depressive Disorder: A Propensity-Adjusted Retrospective Cohort
Study
Robert J. Valuck*, Anne M. Libby, Elaine H. Morrato, Maria A.
Oquendo, Hendricks Brown, Robert D. Gibbons
88.
Mitochondrial Related Gene Expression In Suicide
Marquis P. Vawter*, Simon J. Evans, Prabha V. Choudary, Fan Meng,
Mary E. Atz, Preston Cartagena, David M. Walsh, Jun Li, Hiro
Tomita, Richard M. Myers, Huda Akil, Stanley J. Watson, Edward G.
Jones, William E. Bunney
89.
Altered Sensitivity of Peripheral Blood Leukocytes to Glucocorticoids in
Deployment-Related Postraumatic Stress Disorder
Eric Vermetten*, Carien De Kloet, Annemieke Kavelaars, Angela
Bikker, Ellen Meulman, Herman G. Westenberg, Cobi J. Heijnen
90.
Evidence That SSRI Response in Depression Is Influenced by a Functional
Haplotype in HTR1B and the C-1019G SNP in HTR1A
Sandra M. Villafuerte*, Elizabeth A. Young, Margit Burmeister
145
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91.
The Mu-Opioid Receptor Polymorphism A118G Predicts Cortisol
Responses to Naloxone and Stress
Gary Wand*, Rachel Chong, Lynn Oswald, Xiaoju Yang, Magdalena
Uhart, Ping Lin
92.
5HTTLPR Genotypes and Environmental Stress Interact to Affect Sleep
Quality
Beverly Brummett, Allison Ashley-Koch, Cynthia Kuhn, Melanie
Kail, Jeffery Vance, Stephan Zuchner, Ilene Siegler, John Barefoot,
Redford Williams*
93.
Evidence of Increased CRH Pulsatility in Major Depression
Elizabeth A. Young*, Morton B. Brown, Saulo Ribeiro
94.
Identifying the Most Sensitive Measures and Definitions of Outcome for
Pediatric Bipolar Disorder
Eric A. Youngstrom*, Mark D. Cooperberg, Joseph R. Calabrese,
Robert L. Findling
95.
Robust, Rapid and Relatively Sustained Antidepressant Effects with a
Single-Dose of an NMDA Antagonist in Treatment-Resistant Major
Depression: A Double-Blind Placebo-Controlled Study
Carlos A. Zarate*, Jaskaran Singh, Paul Carlson, Nancy Brutsche,
Rezvan Ameli, David Luckenbaugh, Dennis S. Charney, Husseini K.
Manji
96.
Responsiveness of Mice Deficient in Beta Adrenergic Receptors to
Desipramine and Beta Adrenergic Agonists: Behavioral Effects Observed
Using the Forced-Swim Test (FST) and Differential-Reinforcement-ofLow-Rate (DRL) Schedule
Hanting Zhang*, Lisa R. Stolinski, Ying Huang, James M. O’Donnell
97.
Lithium Regulates P2X7 Receptor Expression and ATP Activation in
Astrocytes: A Novel Therapeutic Target in the Treatment of Bipolar
Disorder?
Lei Zhang*, James E. Barrett, Husseini K. Manji
146
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98.
Abnormal Expression of Transcripts for GKAP and Shank Suggest
Alterations of Interactions Between Metabotropic and Ionotropic
Glutamate Receptors in Schizophrenic Brain
James H. Meador-Woodruff*, Eduardo Reyes, Vahram Haroutunian,
Lars V. Kristiansen
99.
Correlations Between REM Sleep EEG Spectral Analysis and CSF GABA
in Clinically Stable Drug-Free Patients with Schizophrenia: A Pilot Study
Julie Poulin*, Daniel P. Van Kammen, Mary E. Kelley, Roger
Godbout, Thomas C. Neylan, Eric A. Nofzinger, Jeffrey L. Peters,
Guochuan E. Tsai
100.
Medial Temporal Lobe Structures and RGS4 Polymorphisms in FirstEpisode Schizophrenia
Konasale M. Prasad*, Kodavali V. Chowdari, Michael E. Talkowski,
David A. Lewis, Vishwajit L. Nimgaonkar, Matcheri S. Keshavan
101.
The Consortium on the Genetics of Schizophrenia (COGS): Reliability and
Validity of Standardized Assessement of Basic Oculomotor Function in
Schizophrenia Patients, First Degree Relatives and Controls in a Multisite
Study
Allen D. Radant*, Dorcas J. Dobie, Monica E. Calkins, Ann Olincy,
Sean P. Meichle, Debby W. Tsuang
102.
Disrupted Integration of Prefrontal and Hippocampal Activation in
Schizophrenia During Word Encoding and Recognition
John D. Ragland*, Dan Wolf, Mark Elliott, Jeffrey N. Valdez, Ruben
C. Gur, Raquel E. Gur
103.
Bilateral Reduction of Caudate Volumes in the Young, Asymptomatic,
Genetically at Risk Offspring of Patients with Schizophrenia
RP Rajarethinam*, Ameet Upadhyaya, Pon Tsou, Margi Upadhyaya,
Jeffrey Nutche, Matcheri Keshavan
104.
The Orexin-1 Receptor Antagonist SB-334867 Reverses the Depolarization
Inactivation of A9 and A10 Dopamine Neurons Caused by Chronic
Administration of Haloperidol and Olanzapine
Kurt Rasmussen*, Kalpana Merchant, Yili Yang
147
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105.
Second-Generation Antipsychotic Exposure and Patterns of Change in
Metabolic Adverse Effects: A Longitudinal Pharmacoepidemiology Study
from 1988 to 2002
Chris Reist*, Lawrence Albers, Sandor Szabo, Mazan Jamal, Mehrtash
Hashemzadeh, Vural Ozdemir
106.
MEG Gamma Band Activity Reduced in Psychotic Adolescents
Keeran Maharajh, Peter Teale, Don Rojas, Martin Reite*
107.
Randomized Comparison of Olanzapine versus Risperidone for the
Treatment of First Episode Schizophrenia: Four Month Outcomes
Delbert G. Robinson*, Margaret Woerner, Barbara Napolitano, Raman
Patel, Serge Sevy, Handan Gunduz-Bruce, Jose Soto-Perello, Alan
Mendelowitz, Ali Khadivi, Rachel Miller, Joanne McCormack, Beth
Lorell, Martin Lesser, Nina Schooler, John Kane
108.
Olanzapine and Clozapine Rapidly Decrease Whole-Body Insulin
Sensitivity in Rats: Implications for the Diabetic Liability of Certain
Antipsychotics
K L. Houseknecht, A S. Robertson, E M. Gibbs, W J. Zavadoski, F M.
Nedza, D E. Johnson, B K. Koe, H Rollema*
109.
Alteration of Amygdala Inputs to Entorhinal Cortex Through
Dopaminergic Modulation of Voltage-Gated Ion Channels
Amiel Rosenkranz*, Daniel Johnston
110.
Antipsychotic-Like Effects of SCA-136: A Novel 5-HT2C Receptor
Agonist
Karen L. Marquis, Nancy Ator, John Dunlop, Siva Ramamoorthy,
Chad Beyer, Qian Lin, Julie Brennan, Michael Piesla, Charles Ashby,
Boyd Harrison, Ron Magolda, Menelas N. Pangalos, Gary Stack,
Sharon Rosenzweig-Lipson*
111.
Efficacy of Ziprasidone in Schizophrenic Subjects with Differing Levels of
Agitation
Nina R. Schooler*, Jacobo Mintzer, Antony Loebel, Ruoyong Yang
148
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112.
A Pharmacogenetic Test for Prediction of Vulnerability to Tardive
Dyskinesia
Ronnen H. Segman*, Tanya Goltser - Dubner, Fabio Macciardi,
Bernard Lerer
113.
Neuregulin1-Induced Cell Migration of B Lymphoblasts: Possible
Association with Schizophrenia
Yoshitatsu Sei*, Renee Ren-Patterson, Zhen Li, Elizabeth M.
Tunbridge, Michael F. Egan, Bhaskar S. Kolachana, Daniel R.
Weinberger
114.
Differential Methamphetamine-Induced Immediate Early Gene Expression
in the Prefrontal Cortex of High Versus Low Responders
Paul D. Shilling*, Ronald Kuczenski, David S. Segal, Thomas B.
Barrett, John R. Kelsoe
115.
Disruption of Startle Gating in Rats After Systemic D1 Blockade Is
Independent of Prefrontal Cortex and Changes in Sensory Gating.
Jody M. Shoemaker*, Gregory A. Light, Michelle Breier, Hubertus H.
Voet, Richard L. Saint Marie, Alaina C. Neary, Neal R. Swerdlow
116.
Frequency Mismatch Negativity in Mice is Attenuated by Ketamine
Steven J. Siegel*, Richard S. Ehrlichmen, Christina Maxwell, Sonalee
Majumdar
117.
Metabolic Responses to Fatty Meal in Schizophrenic Patients Treated with
Olanzapine or Risperidone
Robert C. Smith*, Jean-Pierre Lindenmayer, Erin Kelly, Adriana
Buga, Melissa Matute, Sumathi Vaidhyanathaswamy, Nabila Sheikh,
Tom Viviano, Santica M. Marcovina
118.
Effects of Smoking and Nicotine Nasal Spray on Cognitive Function in
Schizophrenic Smokers, Schizophrenics Non-Smokers, and Non-Psychotic
Smokers
Erin Kelly, Robert C. Smith*, Anantha Shekhar, Fredrick Molloy,
Timothy Steadman, Nabila Sheikh, Meaghan Kuczora, Alea Khan
149
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119.
Effectiveness and Tolerability Outcomes of Risperidone Long-Acting
Injection Compared to Conventional Depot Antipsychotics in a Canadian
Psychiatric Hospital
Mark Snaterse*, Ron Welch, Pierre Chue
120.
Evidence for Epigenetic Regulation of the 5HT2A Receptor Gene
(5HT2AR). Methylation of Allele C-Specific CpG Sites in 5HT2AR
Correlates with its Expression and eRobust, Rapid and Relatively
Sustained Antidepressant Effects with a Single-Dose of an NMDA
Antagonist in Treatment-Resistant Major Depression: A Double-Blind
Placebo-Controlled Study Expression of DNA Methylase DNMT1
Oxana O. Polesskaya, Christopher Aston, Boris P. Sokolov*
121.
Deficit Syndrome and Memory Function in Schizophrenia
Arielle D. Stanford*, Ronald B. Chin, Binu Thomas, Elena Ivleva,
Carol A. Tamminga
122.
MUTED (6p24.3), a Protein That Binds to Dysbindin (DTNBP1, 6p22.3),
Is Strongly Associated with Schizophrenia and Exhibits Statistical
Epistasis with COMT
Richard E. Straub*, Michael B. Mayhew, Radha K. Vakkalanka,
Bhaskar Kolachana, Terry E. Goldberg, Michael F. Egan, Daniel R.
Weinberger
123.
Bifeprunox: Relationship Between Antipsychotic Potential, EPS Liability
and Dopamine D2 Receptor Occupancy in Rats
Peter Hertel, L Brennum, L Helboe, C K Olsen, M Kreilgard, Karen
Marquis, Torgny Svensson*, A H J Herremans, Mayke Hesselink
124.
Enhanced Cortical Dopamine Output and Antipsychotic-Like Effect of
Raclopride by Low Dose L-Dopa
Torgny Svensson*, Marie-Louise Wadenberg, Amani Eltayb
125.
Effects of Memantine on Startle Gating in Normal Adult Men
Neal R. Swerdlow*, Ashley N. Sutherland, Monique P. Tillemans, Jo
A. Talledo
150
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126.
Lower Anterior Cingulate Grey Matter Volume in Antipsychotic DrugNaive First-Episode Schizophrenia Patients with Cannabis Use
Philip R. Szeszko*, Serge Sevy, Delbert G. Robinson, Sanjiv Kumra,
Claudia I. Rupp, Julia Betensky, Todd Lencz, Manzar Ashtari, John
Kane, Anil K. Malhotra, Handan Gunduz-Bruce, Barbara Napolitano,
Robert M. Bilder
127.
Distinct Roles for Different Homer1 Isoforms in Behaviors Associated
with Prefrontal Cortex Function in vivo
Karen K. Szumlinski*, Kevin D. Lominac, Peter W. Kalivas
128.
Asenapine Displays Unique Long-Term Molecular Effects on Dopamine
Receptor Subtypes
Frank I. Tarazi*, Taylor Moran-Gates, Carla Massari, Erik HF Wong,
Brian Henry, Mohammed Shahid
129.
A Double-Blind, Placebo-Controlled Study of Olanzapine in Adolescents
with Schizophrenia
Ludmila Kryzhanovskaya, Charles Schulz, Christopher J. McDougle,
Jean A. Frazier, Joan Shen, Ralf Dittman, Carol Robertson-Plouch,
Theresa Bauer, Wen Xu, Wei V. Wang, Janice Carlson, Sara Corya,
Mauricio Tohen*
130.
COMT Inhibition Enhances Neuregulin-Induced Cell Migration in B
Lymphoblasts
Elizabeth Tunbridge*, R Ren-Patterson, Z Li, J Chen, J Apud, M
Egan, B Kolachana, P J. Harrison, Y Sei, D R. Weinberger
131.
Chromosome 7q PTC Non-Taster Haplotype is Associated with
Schizophrenia
Bruce I. Turetsky*, Stephen J. Kanes, Mya E. Levy, Paul J. Moberg
132.
The COMT Val158Met Polymorphism and Cognition in Schizophrenia
Elizabeth W. Twamley*, Jenille M. Narvaez, David I. Sitzer, John R.
Kelsoe
133.
Identification of an Interaction Between the Dopamine D1 Receptor and
Niemann-Pick C1 Protein
Gabriel Vargas*, Stanford Chen, Mark Von Zastrow
151
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134.
Are Self-Reports and Physician Impressions of Adherence to Oral
Antipsychotics Related to Objective Measures?
Dawn I. Velligan*, Mei Wang, Desiree Castillo, Scott Bendle, Francis
Lam, Larry Ereshefsky, Pamela Diamond, Alexander L. Miller
135.
Neuroscience-Guided Cognitive Training in Schizophrenia: Preliminary
Data
Sophia Vinogradov*, Christine Holland, Michael Merzenich
136.
Treatment of Cardiac Risk Factors in Patients with Schizophrenia and
Diabetes
Anthony P. Weiss*, David C. Henderson, Jeffrey B. Weilburg, Donald
C. Goff, James B. Meigs, Enrico Cagliero, Richard W. Grant
137.
Aripiprazole Effects in Schizophrenia Patients with High or Low Agitation
Britt West*, James Appel, Stephen Marder, Joseph Pultz, Andrei
Pikalov, Ronald Marcus, Rolando Gutierrez-Esteinou, David Crandall
138.
Anterior Cingulate Bundle Abnormality in Children and Adolescents with
Schizophrenia
Tonya White*, Ayse T. Karagille, Stephane Leherecy, Mustafa Kendi,
Canan Karatekin, Angela Guimaraes, Nicholas Davenport, S. C.
Schulz, Kelvin O. Lim
139.
Altered Cerebral Processing of Reward Uncertainty in Patients with
Schizophrenia While Medication-Free and on Atypical Neuroleptics
Dylan Wint*, Jean-Claude Dreher, Daniella Furman, Paul Koch, Philip
Kohn, Michael Egan, Daniel Weinberger, Karen F. Berman
140.
Asenapine: A Novel Psychotherapeutic Agent with a Unique Human
Receptor Binding Signature
Mohammed Shahid, Erik Wong*, Glenn B. Walker, Ross A. Baker,
Anil S. Jina, Stevin Zorn
141.
Variation in Catecol-O-Methyltransferase and GRM3 on Working Memory
Load and Prefrontal Cortical Physiology
Hao Yang Tan*, Qiang Chen, Steven Sust, Joshua W. Buckholtz,
Richard Straub, Venkata S. Mattay, Michael F. Egan, Daniel R.
Weinberger, Joseph H. Callicott
152
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142.
Cortisol and Cytokines in Chronic and Treatment-Resistant Patients with
Schizophrenia: Association with Psychopathology and Response to
Antipsychotics
Xiang Y. Zhang*, Dong F. Zhou
143.
BDNF Levels and Genotype Are Associated with Antipsychotic-Induced
Weight Gain in Patients with Chronic Schizophrenia
Xiang Y. Zhang*, Yun L. Tan, Dong F. Zhou
144.
Histone Hyper-Acetylation Enhances Memory Storage and Facilitates
Synaptic Plasticity via the Transcription Factor CREB
Ted Abel*, Chris Vecsey, K. Matthew Lattal, Joel Stein, Sara Fabian,
Michelle Attner, Josh Hawk, Marcelo A. Wood
145.
Changes in Natural Killer Cell Function, Inflammatory Signaling and
Plasma IL-6 Production During Acute Stress in Patients with Major
Depression
Oyetunde Alagbe*, Thaddeus Pace, Tanya Mletzko, Jerry Vogt,
Charles Nemeroff, Christine Heim, Andrew Miller
146.
The Phosphodiesterase Type IV Inhibitor, Rolipram, Activates
Septohippocampal Neurons
Min Wu, Elena Morozova, Iryna Dumalska, Ronald S. Duman,
Meenakshi Alreja*
147.
Creation of Designer Biogenic Amine Receptors via Directed Molecular
Evolution
Blaine Armbruster*, Bryan Roth
148.
Elevated Membrane Cholesterol Limits Metabotropic Glutamate Receptor
(mGluR) Suppression of NMDA Function: A Potential Contribution to
Antipsychotic Action?
Andrius Baskys*, Liwei Fang, Moti L. Kashyap, Vaijinath Kamanna,
Ildar T. Bayazitov
149.
Enzymes Coupled with Cyclooxygenase Are Altered in the Brain of
Cyclooxygenase-1 Deficient Mice: Implications for Neuroprotection in
Neuropsychiatric Disorders
Sang-Ho Choi, Francesca Bosetti*
153
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150.
ERK MAP Kinase Signaling in Postmortem Brain of Suicide Subjects:
Differential Regulation of Upstream Raf Kinases Raf-1 and B-Raf
Yogesh Dwivedi*, Robert Conley, Ghanshyam N. Pandey
151.
Adderall® Produces Differential Dopamine Overflow When Compared to
D-Amphetamine in Rat Striatum
Paul E. Glaser*, B. M. Joyce, Garretson D. Epperly, Greg A. Gerhardt
152.
Distinct Roles for MT1 and MT2 Melatonin (MLT) Receptors in MLTMediated Phase Shifts of Circadian Rhythms
R. L. Hudson*, I Stepien, P Ginter, M. L. Dubocovich
153.
Hippocampal Erk Signalling in Stress-Enhanced Aversive Learning
Farahnaz Sananbenesi, Andre Fischer, Christina Schrick, Jelena
Radulovic*
154.
Mood Stabilizers That Downregulate the Brain Arachidonic Acid Cascade
Reduce AP-2 or NF-κB Transcription Factors in Rat Frontal Cortex
Jagadeesh S. Rao*, Richard P. Bazinet, Ho-Joo Lee, Stanley I.
Rapoport
155.
Identification and Characterization of D2 Dopamine Receptor Interacting
Proteins
David R. Sibley*, Lisa A. Hazelwood, R. B. Free, David M. Cabrera
156.
Protein Interactions of the Vesicular Glutamate Transporter, VGLUT1
Susan Voglmaier*, Robert H. Edwards
157.
Dexras1 Is a Novel Modulator of Neuronal Adenylyl Cyclases
Chau H. Nguyen, Val J. Watts*
158.
Long-Term Efficacy of Ziprasidone in Treatment-Refractory Schizophrenia
Steven G. Potkin, Antony Loebel*, John Kane, Cynthia Siu
154
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159.
Dopamine and Serotonin Receptor Occupancy of Long Acting Injectable
Risperidone in Patients with Schizophrenia
Steven G. Potkin*, Jogesh Mukherjee, Georges Gharabawi, Daphne
Collins
160.
Adult Outcome in Children with Obsessive-Compulsive Disorder
Michael H. Bloch*, Britt Craiglow, Philip Dombrowski, Katie Panza,
Denis Sukhodolsky, Bradley S. Peterson, James Leckman
161.
Regulation of Apolipoprotein L2 in Human Drug Abuse
Elin Lehrmann*, Carlo Colantuoni, Thomas M. Hyde, Joel E.
Kleinman, Kevin G. Becker, William J. Freed
155
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NMP 2006.qxp
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NONMEMBER
PARTICIPANTS
NMP 2006.qxp
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NMP 2006.qxp
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Roger Albin
Professor of Neurology
University of Michigan Health System
200 Zina Pitcher Place
Kresge Building 111, Rm. 4412
Ann Arbor, MI 48109-0585
Ruben Baler
National Institute of Health/NIDA
6001 Executive Blvd.
NSC Bldg., Room 5241
Bethesda, MD 20892
Ben Barres
Stanford University School of Medicine
299 Campus Drive
Fairchild Bldg., Room D235
Stanford, CA 94305-5125
Paul Andreason
FDA-Division of Psychiatry Products
Building 22, Room 4112
10903 New Hampshire Avenue
Silver Spring, MD 20993-0002
Jill Becker
University of Michigan
530 Church Street
Ann Arbor, MI 48109
Stewart Anderson
Box 244
1300 York Avenue
New York, NY 10021
Francesco Benedetti
San Raffaele Turro
Via Stamira D'Ancona 20
Milano 20127
ITALY
Eva Anton
University of North Carolina, Chapel
Hill
105 Mason Farm Road
Neuroscience Center, Room 7109B
Chapel Hill, NC 27599
Thomas Biederer
Yale University School of Medicine
Mol Biophys & Biochem
New Haven, CT 06520-8024
Ben Bahr
372 Fairfield Road
Unit-2092
Storrs, CT 06269-2092
Michel Bouvier
Université De Montréal
Département De Biochimie Unive
2900 Edouard Montpetit
Montreal, QUE H3C 3J7
CANADA
Vaishali Bakshi
Wisconsin Psychiatric Institute &
Clinics
6001 Research Park Blvd
Dept. of Psychiatry
Madison, WI 53719
Jan Buitelaar
159
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Andres Buonanno
National Institute of Health
35 Lincoln Drive
MSC 3713, Bldg 35, Room 2C1000
Bethesda, MD 20892
Jin-chung Chen
Jingshan Chen
9000 Rockville Pike
Bldg. 10, Room 4N307
Bethesda, MD 20892
Donald Burns
Merck Research Labs
WP44C-2, Box 4
Sumneytown Pike
West Point, PA 19486
Daniel Clauw
University of Michigan School of
Medicine
Division of Rheumatology
Ann Arbor, MI 48109-0723
M. Catheine Bushnell
McGill Centre for Research on Pain
3640 University Street
Room M/19
Montreal H3A 2B2
CANADA
Lisa Conti
University of Connecticut Health Center
263 Farmington Avenue
Psychiatry, MC 1410
Farmington, CT 06030
Pamela Butler
Nathan Kline Institute for Psychiatric
Research
140 Old Orangeburg Road
Orangeburg, NY 10962
Gabriel Corfas
Harvard Medical School
Dept of Neurology
300 Longwood Avenue
Boston, MA 02115
Patrizia Caldirola
Biovitrum
Berzeliusveg 8
Stockholm 11276
SWEDEN
Rebecca Craft
Washington State University
Dept. of Psychology
P.O. Box 644820
Pullman, WA 99164-4820
Dave Ceryak
Law Division
Lilly Corporate Center
Indianapolis, IN 46285
John Cryan
University College Cork
School of Pharmacy
Dept of Pharmacology
Cork City
IRELAND
Kiki Chang
Stanford University
Psychiatry
401 Quarry Road
Stanford, CA 94305
160
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Cyril D'Souza
Psychiatry Dept
20 York Street
New Haven, CT 06510
Lars Farde
AstraZeneca R&D
Global Discovery Research Area
CNS Pain Control
Sodertalje SE-15185
SWEDEN
Mony De Leon
New York University School of
Medicine
560 First Avenue
New York, NY 10016
Joram Feldon
Swiss Federal Institute of Technology
Zurich
Schorenstrasse 16
Schwerzenbach 8603
SWITZERLAND
Michael Dean
National Cancer Institute
Laboratory of Genomic Diversity
Bld. 560, Rm. 21-18
Frederick, MD 21702
Anna Francesconi
Albert Einstein College of Medicine
Dept of Neuroscience
1300 Morris Park Avenue
Bronx, NY 10461
Jing Du
49 Convent Drive
Bldg. 49, Room B1C60
Bethesda, MD 20892
John Gabrieli
Department of Psychology
Jordan Hall
Building 420, Room 300
Stanford, CA 94305
Laura Dugan
UCSD
9500 Gilman Drive (0665)
San Diego, CA 92093
Albert Galaburda
330 Brookline Avenue, KS-274
Boston, MA 02215
Howard Eichenbaum
Boston University
2 Cummington Street
Boston, MA 02215
S. Gatley
490 Bell Avenue
Upton, NY 11973
Christopher Evans
NPI
760 Westwood Plaza
Psychiatry & Behavioral Sciences
Los Angeles, CA 90024-1759
Jay Gingrich
New York State Psychiatry Institute
Unit 40
1051 Riverside Drive
New York, NY 10032
161
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Richard Glass
JAMA
1033 E 49th Street
Chicago, IL 60615
Chang-Gyu Hahn
415 Curie Blvd
545 CRB
Philadelphia, PA 19014
Paul Glimcher
New York University
4 Washington Place
Room 809
New York, NY 10003
Maureen Hahn
Instructor
Vanderbilt University Medical Center
465 21st Avenue South
7141 MRB III
Nashville, TN 37232
Steven Goldberg
National Institute on Drug Abuse
5500 Nathan Shock Drive
Preclinical Pharmacology
Baltimore, MD 21224
Ronald Hammer
Tufts University School of Medicine
750 Washington Street
Box 1007
Boston, MA 02111
James E. Goldman
Professor of Pathology and
Director, Division of Neuropathology
Columbia University College of P&S
630 West 168th Street, P&S 15-420
New York, NY 10032
Stephan Heckers
McLean Hospital
115 Mill Street
Schizophrenia & Bipolar Disease
Belmont, MA 02478
Guy Goodwin
Oxford University
Warneford Hospital Lane
Oxford OX3 7JX
UNITED KINGDOM
Markus Heilig
National Institute of Health/NIAAA
10 Center Drive
10-CRC/15330
Bethesda, MD 20892-1610
Todd Gould
Bldg. 35, Room 1C-912
9000 Rockville Pike
Fred Helmstetter
University of Wisconsin
Dept of Psychology
P.O. Box 413
Milwaukee, WI 53201
Heinz Grunze
Department of Psychiatry, LMU
Nussbaumastrasse 7
Munich 80336
GERMANY
Bart Hoebel
Princeton University
Princeton, NJ 08544
162
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William Horan
UCLA
Dept of Psychiatry & Biobehavioral
Science
300 UCLA Medical Plaza, Suite 2240
Los Angeles, CA 90095
Kwang-Soo Kim
McLean Hospital/Harvard Medical
School
115 Mill Street
Belmont, MA 02478
Becky Kinkead
Emory University School of Medicine
101 Woodruff Circle
Suite 4000 WMRB
Atlanta, GA 30322
Z. Huang
Beckman 220
One Bungtown Road
Cold Spring Harbor, NY 11724
Richard Huganir
Johns Hopkins University School of
Medicine
Dept of Neuroscience
725 Wolfe Street, PCTB 904A
Baltimore, MD 21205
Peter Klein
415 Curie Blvd
364 Clinical Research Bldg
Philadelphia, PA 19104-6140
Cary Lai
Scripps Research Institute
10550 N. Torrey Pines Road
La Jolla, CA 92037
Sandra Johnson
St. Louis University
3700 Lindell Blvd.
Saint Louis, MO 63108
Ruth Lanius
University of Western Ontario
339 Windermere Road, P.O. Box 5339
Room 10N07
London, Ontario N6A 5A5
CANADA
Julie Kauer
Brown University
Biomedical Center, Department of
MPPB
PO Box G-B4
Providence, RI 02912
Amanda Law
University of Oxford
Warneford Hospital, Headington
Dept. of Psychiatry
Oxford
UNITED KINGDOM
Hans Keirstead
University of California, Irvine
2111 Gillespie Neuroscience Facility
Irvine, CA 92697
Terence Ketter
Department of Psychiatry
Room 2124
401 Quarry Road
Ellen Leibenluft
National Institute of Mental Health, NIH
Mood & Anxiety Program
Bldg. 15K, MSC 2670
163
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Sarah Leibowitz
The Rockefeller University
1230 York Avenue
New York, NY 10021
John Littleton
University of Kentucky
Cooper and University Drive
Lexington, KY 40546
Vance Lemmon
University of Miami Medical School
Lois Pope LIFE Center, Room 4-16
1095 NW 14th Terrace
Miami, FL 33136
David Lyons
Stanford University
1201 Welch Rd
Psychiatry, MSLS, Room 104
Stanford, CA 94305
Anne Lesage
Johnson & Johnson Pharmaceutical
R&D
Turnhoutseweg 30
CNS Discovery Research
Beerse B2340
BELGIUM
Pierre Magistretti
Director, Center for Psychiatric
Neuroscience
Department of Psychiatry - CHUV and
University of Lausanne (UNIL),
Medical School
Professor of Neuroscience
Brain and Mind Institute
Ecole Polytechnique Federale Lausanne
(EPFL)
Rue du Bugnon 7, CH-1005 Lausanne
SWITZERLAND
Lydia Lewis
The Depression and Bipolar Support
Alliance
730 N Franklin
Suite 501
Chicago, IL 60610
Steven Maier
University of Colorado
Psychology
Campus Box 345
Boulder, CO 80309
Shon Lewis
G.907 Stopford Building
Oxford Road
Manchester M13 9PT
UNITED KINGDOM
Robert Malison
Yale School of Medicine
Clinical Neuroscience Research Unit
34 Park Street
New Haven, CT 06519
Raye Litten
National Institute on Alcohol Abuse &
Alcoholism
5635 Fishers Lane
Room 2041
Shaila Mani
Baylor School of Medicine
One Baylor Plaza
123D
Houston, TX 77030
164
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Kelsey Martin
UCLA, Brain Research Institute, Gonda
Bldg.
Department of Psychiatry
695 Charles Young Drive South
Los Angeles, CA 90095-1761
David Meltzer
University of Chicago
5841 S Maryland
MC 2007
Chicago, IL 60637
Graeme Milligan
University of Glasgow
Davidson Building
University Avenue
Glasgow G12 8QQ
UNITED KINGDOM
Emeran Mayer
UCLA/GLA VA HS
Bldg 115/Room 223
11301 Wilshire Blvd
Susan McConnell
Stanford University
Herrin Labs 115
385 Serra Mall
Pendleton Montague
Baylor College of Medicine
Center for Theoretical Neuroscience
Division of Neuroscience
1 Baylor Plaza
Houston, TX 77030
Joseph McEvoy
Duke University Medical Center/John
Umstead Hospital
1003 12th Street
Bldg. 32
Butner, NC 27509
Anne Murphy
Center for Behavioral Neuroscience
P.O. Box 4010
Atlanta, GA 30302
Jaap Murre
Roeterstraat 15
Amsterdam 1018
NETHERLANDS
Ronald McKay
NINDS, Laboratory of Molecular
Biology
Porter Neurosciences Research Center
Building 35, Room 3A-201
35 Covent Drive, MSC 3703
Robert Muse
Stein, Mitchell & Mezines
1100 Connecticut Avenue, NW
Suite 1100
Washington, DC 20036
Michael Meaney
Douglas Hospital Research Center
6875 LaSalle Blvd
Montreal, Quebec H4H 1R3
CANADA
Vincent Mutel
Addex Pharmaceuticals, Ltd.
12, Chemin Des Aulx
Plan Les Ouates CH-1228
SWITZERLAND
165
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Toshitaka Nabeshima
Professor & Director
Nagoya University Graduate School of
Medicine
Dept of Neuropsychopharmacol &
Hosp Phar
65 Touruma-cho, Showa-Ku
Nagoya 486-8560
JAPAN
Paul Patterson
California Institute of Technology
Div Biol 216-76
Pasadena, CA 91125
Jane Pearson
Assoc Dir Preventive Interventions
NIMH
Div of Services & Intervention Research
6001 Executive Blvd, Rm 7160
MSC 9635
Ann Neale
60 Stone Pine Road
Suite 200
Half Moon Bay, CA 94019
Laura Peoples
University of Pennsylvania
3720 Walnut Street
David Nelson
Lilly Corporate Center
Drop Code 0510
Indianapolis, IN 46285
Srinivasan Pillay
McLean Hospital
115 Mill Street
Brain Imaging Center
Belmont, MA 02478
Raymond Niaura
Brown Medical School
345 Blackstone Blvd.
Psychiatry
Providence, RI 02906
Diego Pizzagalli
Harvard University
Dept of Psychology
1220 William James Hall
33 Kirkland Street
Cambridge, MA 02138
David Nutt
University of Bristol
Psychopharmacology Unit
Whitson Street
Bristol BS1 3NY
UNITED KINGDOM
Jonathan Pollock
National Institute on Drug Abuse
Division of Neuroscience & Behavioral
Research
6001 Executive Blvd., Room 4282
MCS9555
Valerie Olson
Acting Assistant Professor
University of Washington
VA Puget Sound Health Care System
Dept of Psychiatry & Behavioral
Science
1660 S. Columbia Way
Seattle, WA 98108
166
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Maurizio Popoli
University of Milano
Center of Neuropharmacology
Dept. of Pharmacology Sci., Via Balza
Milano 20133
ITALY
Donald Rosenstein
Office of the Clinical Director
Bldg 10-CRC, Room 6-5340
10 Center Drive
Bethesda, MD 20892
Richard Porter
Hoffmann La Roche
Bldg. 69-452
Basel
SWITZERLAND
Barbara Rothbaum
Psychiatry, The Emory Clinic
1365 Clifton Road
Atlanta, GA 30322
A. Redish
University of Minnesota
6-145 Jackson Hall
321 Church Street
Minneapolis, MN 55455
Barbara Sahakian
University of Cambridge School of
Clinical Medicine
Department of Psychiatry, Box 189
Audenbrookes Hospital
Cambridge, Eng CB22QQ
UNITED KINGDOM
Victoria Risbrough
University of California, San Diego
9500 Gilman Drive
Psychiatry MC0804
La Jolla, CA 92093
Larry Scahill
Yale Child Study Center
230 South Frontage Road
P O Box 207900
New Haven, CT 06520-7900
Angela Roberts
University of Cambridge
Dept. of Anatomy
Downing Street
Cambridge CB2 3DY
UNITED KINGDOM
Peter Scheiffele
Columbia University
Dept of Physiol & Cell Biophys
630 West 168th St P&S 11-511, MC22
New York, NY 10032
Robert Rosenheck
VA Connecticut Healthcare System
NEPEC #182, Bldg. 8
950 Campbell Avenue
West Haven, CT 06516
Yavin Shaham
IRP/NIDA
5500 Nathan Shock Drive
Baltimore, MD 21044
167
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Philip Shaw
10 Center Drive, MSC 1600
Bethesda, MD 20892
Dietrich Stephan
The Translational Genomics Research
Institute
445 North Fifth Street
Phoenix, AZ 85004
Saul Shiffman
Smoking Research Group
130 N. Bellefield Avenue
Suite 510
Pittsburgh, PA 15213
David Talmage
Columbia University
Institute of Human Nutrition
701 W 168th Street
New York, NY 10032
David Silbersweig
Weill Medical College of Cornell Univ.
New York Presbyterian Hospital
1300 York Avenue
Box 140, Room F1303
New York, NY 10021
Todd Thiele
University of North Carolina
Dept. of Psychology
CB 3270
Chapel Hill, NC 27599
Steven Thomas
University of Pennsylvania
3620 Hamilton Walk
103 John Morgan Bldg.
Rajita Sinha
Yale University School of Medicine
34 Park Street
Room S110
New Haven, CT 06519
Andrea Tone
Professor & Director of Graduate
Studies
McGill University
3647 Peel Street
Faculty of Medicine
Montreal H3A 1X1
CANADA
Rainier Spanagel
J5
Mannheim 68159
GERMANY
Thomas Spencer
Massachusetts General Hospital
55 Fruit Street
YAW 6900
Boston, MA 02114
Bruce Trapp
Cleveland Clinic
9500 Euclid Avenue
Dept. of Neuroscience NC30
Cleveland, OH 44195
Lalit Srivastava
McGill University
Verdun, Quebec H4H 1R3
CANADA
168
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Hiroshi Ujike
Okayama Graduate School of Medicine
2-5-1 Shikata-cho
Okayama 700-8558
JAPAN
John Walkup
Johns Hopkins Hospital
CMSC 314
600 N. Wolfe Street
Baltimore, MD 21287-3325
Leslie Ungerleider
10 Center Drive
Bldg. 10, MSC-1366
Stephen Warren
Dept of Human Genetics
Atlanta, GA 30322
Cynthia Weickert
10 Center Drive
Maarten Van Den Buuse
Mental Health Research Institute
Behavioral Neuroscience Laboratory
155 Oak Street
Parkville 3052
AUSTRALIA
David Weinshenker
Assistant Professor
Emory University
Whitehead Building, Suite 301
615 Michael Street
Atlanta, GA 30322
Marquis Vawter
University of California, Irvine
Gillespie, Room 2119
Irvine, CA 92697-1675
Eduard Vieta
University of Barcelona, Hospital Clinic
Villarroel 170, Rossello 140
Barcelona, NJ 08036
SPAIN
Franz Vollenweider
University Hospital of Psychiatry
University of Zurich
Lenggstrasse 31
PO Box 68
Zurich CH-8032
SWITZERLAND
Lois Winsky
Division of Neurosci MSC 9641
Room 7184
6001 Executive Blvd
Bethseda, MD 20892-9641
Ruth Wood
Keck of Medicine of USC
1333 San Pablo Street
BMT 408A
169
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James Woodgett
Princess Margaret Hospital
610 University Avenue
10th Floor, Room 622
Toronto, ON M5G 2M9
CANADA
Kiyofumi Yamada
Kanazawa University Graduate School
of Natural Science
Kakuma-Machi
Kanazawa
JAPAN
Larry Young
Associate Professor
Emory University
Dept. of Psychiatry
Yerkes Research Center
954 Gatewood Road
Atlanta, GA 30322
James Zacny
University of Chicago
5841 S. Maryland Avenue
MC4028
Chicago, IL 60637
Sidney Zisook
University of California, San Diego
9500 Gilman Drive
0603R
La Jolla, CA 92093
170
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APPENDIX
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Disclosure Statement
It is the policy of Vanderbilt University School of Medicine that the information
presented at Vanderbilt CME activities will be unbiased and based on scientific evidence. To help readers of this enduring material make judgments
about the presence of bias, disclosure of the financial relationships of speakers and Vanderbilt with commercial entities that produce or market products
or services related to the content of this CME activity, if any, are listed below:
Anissa Abi-Dargham
Honorarium: Bristol-Myers Squibb, Otsuka, Sanofi-Aventis
Grant/Research Support: Bristol-Myers Squibb
Steven Arnold
Consultant: Esai, Merck
Gary Aston-Jones
Consultant: Sanofi Aventis
Speaker’s Bureau: Sanofi Aventis
Mark Bear
Consultant: Seaside Therapeutics
Hilary Blumberg
Honorarium: Abbott, Lilly
Theresa Branchek
Stock Shareholder: Lundbeck
Jan Buitelaar
Honorarium: Eli Lilly, Janssen Cilag BV
Consultant: Abbott, Eli Lilly, Janssen Cilag BV, Medice, Shire
William Bunney, Jr.
Consultant: Thuris Corporation
Stock Shareholder: Thuris Corporation
H. Donald Burns
Stock Shareholder: Merck
Other, Employee: Merck
173
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William Carpenter
Consultant: Janssen, Pfizer, Solvay, Wyeth
Dave Ceryak
Stock Shareholder: Eli Lilly and Company
Other, Employee: Eli Lilly and Company
Kiki Chang
Honorarium: Abbott Labs, AstraZeneca, GlaxoSmithKline, Lilly, Shire US
Grant/Research Support: Abbott Labs, AstraZeneca, GlaxoSmithKline,
Otsuka Pharmaceuticals
Consultant: Abbott Labs, AstraZeneca, GlaxoSmithKline, Lilly, Shire US
Daniel Clauw
Consultant: Cypress Biosciences
Stock Shareholder: Cypress Biosciences
John F. Cryan
Other, Employee: Novartis Pharma AG
John Csernansky
Honorarium: Bristol-Myers Squibb, Janssen
Grant/Research Support: AstraZeneca, Bristol-Myers Squibb, Eli Lilly,
Forest Pharmaceuticals, Pfizer
Consultant: Aventis Sanofi
Mony de Leon
Grant/Research Support: Forest Labs, Janssen
Ariel Deutch
Grant/Research Support: Eli Lilly, Pfizer
Consultant: Eli Lilly
Speaker’s Bureau: Eli Lilly
Margarita Dubocovich
Honorarium: Pfizer
Consultant: Shire Pharmaceuticals Group
Lars Farde
Stock Shareholder: AstraZeneca
174
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Colin Fish
Stock Shareholder: GlaxoSmithKline
Other, Employee: GlaxoSmithKline
Richard Frank
Other, Employee: GE Healthcare
Paul Gaylo
Stock Shareholder: Eli Lilly & Company
Other, Employee: Eli Lilly & Company
Mark Geyer
Consultant: Abbott, Acadia, Addex, Avera, Cenomed, Lilly, Nura, Repligen,
Serono, Solvay, Vertex
Grant/Research Support: GlaxoSmithKline, Repligen
Stock Shareholder: San Diego Instruments
Richard Glass
Other, Employee: Deputy Editor of JAMA, American Medical Association
Alexander Glassman
Consultant: AstraZeneca, GlaxoSmithKline, Lilly, Ono Pharma, Pfizer
Speaker’s Bureau: AstraZeneca, GlaxoSmithKline, Pfizer
Ira Glick
Grant/Research Support: AstraZeneca, Bristol-Myers Squibb,
GlaxoSmithKline, Lilly, Pfizer, Shire, Solvay
Consultant: AstraZeneca, Bristol-Myers Squibb, Lilly, Pfizer
Speaker’s Bureau: AstraZeneca, Bristol-Myers Squibb, Janssen, Lilly, Pfizer
Stock Shareholder: Janssen
Guy Goodwin
Honorarium: AstraZeneca, Bristol-Myers Squibb, GlaxoSmithKline, Lilly,
Lundbeck, Sanofi-Aventis
Grant/Research Support: Sanofi-Aventis, Servier
Consultant: Bristol-Myers Squibb, GlaxoSmithKline, Sanofi-Aventis, Servier,
Wyeth
175
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Anthony Grace
Consultant: Novartis, Servier, Taisho
Heinz Grunze
Grant/Research Support: Novartis Germany, UCB Belgium
Speaker’s Bureau: AstraZeneca, Bristol-Myers Squibb, GlaxoSmithKline,
Pfizer
Ruben Gur
Grant/Research Support: Merck
Consultant: Brain Resource Center Sydney, CogTest LTD London, Eli Lilly
Chang-Gyu Hahn
Consultant: Pfizer Pharmaceuticals
Richard Huganir
Consultant: Intra-cellular Therapeutics Inc, Saegis
Other, Royalties: Upstate Biotechnology
Jonathan Javitch
Consultant: Novasite Pharmaceuticals
Dilip Jeste
Consultant: AstraZeneca, Bristol-Myers Squibb, Eli Lilly, Janssen, Solvay,
Wyeth
Grant/Research Support: Janssen
Ned Kalin
Grant/Research Support: Dana Foundation, NIH, Stanley Foundation
Consultant: Bristol-Myers Squibb, Corcept, Cyberonics, Cypress, Forest
Laboratories, GlaxoSmithKline, Janssen Pharmaceutica, Neurocrine Inc,
Novartis, Otsuka America Pharmaceutical Inc, Sanofi-Synthelabo,
Somerset Pharmaceuticals, Wyeth Pharmaceuticals
Speaker’s Bureau: Janssen Pharmaceuticals, Wyeth Pharmaceuticals
Stock Shareholder: Corcept, Neurocrine Inc.
Other, Owner: Promoter Neurosciences, LLC
Shitij Kapur
Grant/Research Support: AstraZeneca, Eli Lilly, EMD, Janssen,
Neuromolecul
Consultant: AstraZeneca, Bristol-Myers Squibb, Eli Lilly, Gla
Speaker’s Bureau: AstraZeneca, Bristol-Myers Squibb, Eli Lilly, Gla
176
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Ira Katz
Grant/Research Support: Janssen
Consultant: AstraZeneca, Janssen, Lilly
John Kelsoe
Speaker’s Bureau: GlaxoSmithKline
Stock Shareholder: Psynomics, Inc.
James Kennedy
Consultant: GlaxoSmithKline
Terrence Ketter
Honorarium: Abbott Laboratories, AstraZeneca, Bristol-Myers Squibb, Eli
Lilly & Company, GlaxoSmithKline, Janssen Pharmaceutica Products,
Novartis Pharmaceuticals Corporation, Pfizer, Shire Pharmaceuticals
Group
Grant/Research Support: Abbott Laboratories, AstraZeneca, Bristol-Myers
Squibb, Eisai, Elan Pharmaceuticals, Eli Lilly & Company,
GlaxoSmithKline, Janssen Pharmaceutica Products, Novartis
Pharmaceuticals Corporation, Shire Pharmaceuticals Group, Solvay
Pharmaceuticals, Wyeth Pharmaceuticals
Consultant: Abbott Laboratories, AstraZeneca, Bristol-Myers Squibb,
Cephalon Inc, Corcept Therapeutics, Elan Pharmaceuticals, Eli Lilly &
Company, Forest Laboratories, GlaxoSmithKline, Janssen
Pharmaceutica Products, Jazz Pharmaceuticals, Novartis
Pharmaceuticals Corporation, Pfizer, Shire Pharmaceuticals Group,
Solvay Pharmaceuticals, UCB Pharmaceuticals, Wyeth Pharmaceuticals
Becky Kinkead
Grant/Research Support: Bristol-Myers-Squibb, Merck, NIMH, Pfizer
Pharmaceuticals, Solvay
Donald Klein
Consultant: Vela Pharmaceutical, Vivometrics
Hartmuth Kolb
Other, Employee: Siemens Molecular Imaging
George Koob
Consultant: Alkermes, Forest Laboratories, Merck/Lipha
177
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Anne Lesage
Other, Employee: Johnson&Johnson Pharmaceutical R & D
David Lewis
Grant/Research Support: Lilly, Merck, Pfizer
Consultant: Lilly, Merck, Pfizer
Shon Lewis
Honorarium: Astra Zenica, Bristol Myers Squibb, GlaxoSmithKline, Janssen,
Lilly, Lundbeck, Novartis, Pfizer, Wyeth
Alfred Lewy
Other, Patents: OHSU
Jeffrey Lieberman
Janssen, Pfizer
Consultant: AstraZeneca, Bristol-Myers Squibb, Eli Lilly, Janssen, Pfizer
Other, Advisory Board: AstraZeneca, Bristol-Myers Squibb, Eli Lilly,
Janssen, Pfizer
John Littleton
Honorarium: Forest Laboratories
Grant/Research Support: Merck s.a.
Consultant: Forest Laboratories, Merck s.a.
Speaker’s Bureau: Forest Laboratories
Stock Shareholder: Naprogenix Inc
Athina Markou
Grant/Research Support: Novartis
Barbara Mason
Consultant: Forest, Somaxon
Speaker’s Bureau: Forest
Other, Medication Supply: Pfizer Pharmaceuticals
Emeran Mayer
Consultant: Allergan, Amgen, AstraZeneca, Avera, GSK, Lilly
Consultant: J&J, Merck, Novartis, Solvay
Grant/Research Support: Novartis, GSK, Lilly
178
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Christopher McDougle
Grant/Research Support: AstraZeneca, Bristol-Myers Squibb, Eli Lilly and
Co, Janssen Pharmaceutica, PediaMed
Consultant: Bristol-Myers Squibb, Eli Lilly and Co, Janssen Pharmaceutica,
PediaMed
Speaker’s Bureau: Bristol-Myers Squibb, Janssen Pharmaceutica
Joseph McEvoy
Honorarium: AstraZeneca, Bristol-Myers, Janssen, Lilly, Pfizer
Grant/Research Support: AstraZeneca, Bristol-Myers, Janssen, Lilly, Pfizer
David Meltzer
Grant/Research Support: Merck
Roger Meyer
Grant/Research Support: Forest, Sepracor, Star Scientific
Consultant: Best Practice Management Inc., Cephalon, Memory
Pharmaceuticals, NABI, Neurim, Ovation, Sanofi, Sepracor, Solvay, Star
Scientific
Stock Shareholder: Best Practice Management Inc
Other, Company Contract: Abbott Pharmaceuticals, AstraZeneca, BristolMyers Squibb, DAS, GlaxoSmithKline, Janssen, J & J Research, Eli Lilly,
M’s Science, Novartis, Pfizer, Prestwick Pharmaceuticals, Takeda
Graeme Milligan
Grant/Research Support: Cara Therapeutics, Pfizer
Consultant: Amersham Biosciences, Boehringer Ingelheim, Cara
Therapeutics, Novasite Pharmaceuticals
John Morris
Grant/Research Support: Elan, Wyeth
Consultant: Amgen, Axonyx, Bristol-MyersSquibb, Elan, Forest Labs,
GlaxoSmithKline, Johnson & Johnson, Neurochem, Novartis, SanofiAventis
Speaker’s Bureau: Forest Labs
Ann Neale
Other, Employee: Saegis Pharmaceuticals
David Nelson
Other, Employee: Eli Lilly and Company
179
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Page 180
Charles Nemeroff
Grant/Research Support: Abbott Laboratories; AFSP; AstraZeneca; BristolMyers-Squibb; Forest Laboratories; GlaxoSmithKline; Janssen
Pharmaceutica; NARSAD; NIMH; Pfizer Pharmaceuticals; Stanley
Foundation/NAMI; Wyeth-Ayerst
Consultant: Abbott Laboratories; Acadia Pharmaceuticals; Bristol-MyersSquibb; Corcept; Cypress Biosciences; Cyberonics; Forest Laboratories;
GlaxoSmithKline; Janssen Pharmaceutica; Otsuka; Pfizer
Pharmaceuticals; Quintiles; Wyeth-Ayerst
Speaker’s Bureau: Abbott Laboratories; GlaxoSmithKline; Janssen
Pharmaceutica; Pfizer Pharmaceuticals
Stock Shareholder: Corcept; Cypress Biosciences; Neurocrine Biosciences;
Acadia Pharmaceuticals
Other, Board of Directors: American Foundation for Suicide Prevention
(AFSP); American Psychiatric Institute for Research and Education
(APIRE); George West Mental Health Foundation; Novadel
Pharmaceuticals
Other, Equity: Reevax; BMC-JR LLC; CeNeRx
Other, Patents: method and devices for transdermal delivery of lithium
(US 6,375,990 B1); method to estimate serotonin and norepinephrine
transporter occupancy after drug treatment using patient or animal
serum (provisional filing April, 2001)
Raymond Niaura
Consultant: GlaxoSmithKline
David J. Nutt
Grant/Research Support: AstraZeneca, GlaxoSmithKline, Janssen, Merck
Sharp & Dohme, Organon, Wyeth
Consultant: AstraZeneca, GlaxoSmithKline, Janssen, Merck Sharp &
Dohme, Organon, Wyeth
Speaker’s Bureau: AstraZeneca, GlaxoSmithKline, Janssen, Merck Sharp &
Dohme, Organon, Wyeth
Stock Shareholder: GlaxoSmithKline
Charles O'Brien
Grant/Research Support: Pfizer
Consultant: Alkermes, Forest, McNeil
Steven Paul
Stock Shareholder: Eli Lilly & Company
Other, Employee: Eli Lilly & Company
180
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Page 181
Richard Porter
Grant/Research Support: Roche
Other, Employee: Roche
William Potter
Other, Employee: Merck Research Labs
Mark Rasenick
Grant/Research Support: Genzyme, NIH, Pfizer
Murray Raskind
Consultant: Bristol-Myers Squibb, Forest Laboratories, Ortho-McNeil
Neurologics
Speaker’s Bureau: Bristol-Myers Squibb, Forest Laboratories, Ortho-McNeil
Neurologics
Trevor Robbins
Honorarium: Lundbeck, Pfizer, Roche
Grant/Research Support: Cephalon, Merck Sharp & Dohme
Consultant: Cambrideg Cognition, Eli Lilly
Speaker’s Bureau: Lundbeck, Pfizer, Roche
Stock Shareholder: CENES plc
Robert Rosenheck
Honorarium: Janssen
Consultant: Bristol Myers Squibb
Barbara Rothbaum
Stock Shareholder: Virtually Better
Barbara Sahakian
Consultant: Cambridge Cognition Ltd (UK)
Lawrence Scahill
Consultant: Bristol-Myers Squibb, Janssen, Pfizer
181
Appendix 2006.qxp
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Page 182
Alan Schatzberg
Honorarium: Lilly
Grant/Research Support: Bristol-Myers Squibb, Eli Lilly, GlaxoSmithKline,
Somerset, Wyeth
Consultant: Abbott, Aventis, BrainCells, Bristol-Myers Squibb, Corcept, Eli
Lilly, Forest Labs, GlaxoSmithKline, Innapharma, Janssen, Neuronetics,
Organon, Pfizer, Somerset, Somaxon, Wyeth
Speaker’s Bureau: Abbott, Aventis, BrainCells, Bristol-Myers Squibb,
Corcept, Eli Lilly, Forest Labs, GlaxoSmithKline, Innapharma, Janssen,
Neuronetics, Organon, Pfizer, Somerset, Somaxon, Wyeth
Other, Equity: BrainCells, Corcept, Elan, Merck, Organon, Pfizer, Somaxon
Lon Schneider
Grant/Research Support: Bristol-Myers Squibb, Janssen, Pfizer
Consultant: AstraZeneca, Bristol-Myers Squibb, Janssen, Pfizer
Saul Shiffman
Consultant: GlaxoSmithKline Inc
Other, Ownership: Invivodata, inc
Gary Small
Other, Patent: FDDNP-PET: Siemens
Thomas Spencer
Honorarium: Eli Lilly & Co, Janssen Pharmaceutical, McNeil
Pharmaceutical, Novartis Pharmaceutical, Shire Laboratories
Grant/Research: Eli Lilly & Co, Janssen Pharmaceutical, McNeil
Consultant: Eli Lilly & Co, Janssen Pharmaceutical, McNeil Pharmaceutical,
Novartis Pharmaceutical, Shire Laboratories
Speaker’s Bureau: Eli Lilly & Co, Janssen Pharmaceutical, McNeil
Stephen Strakowski
Grant/Research Support: AstraZeneca, Forest, Janssen, Lilly
Consultant: OMP, Pfizer
Speaker’s Bureau: AstraZeneca, Bristol-Myers Squibb, Forest, Janssen,
Lilly, OMP, Pfizer
Trey Sunderland
Honorarium: Lundbeck, Pfizer
Consultant: AstraZeneca, Pfizer
182
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Page 183
Robert Swift
Grant/Research Support: Bristol-Myers Squibb, Forest Laboratories, OrthoMcNeil, Pfizer Inc
Consultant: Alkermes, Forest Laboratories, Pfizer Inc
Speaker’s Bureau: Forest Laboratories
Pierre Tariot
Grant/Research Support: AstraZeneca, Forest, Janssen, Lilly, Pfizer
Consultant: AstraZeneca, Forest, Lilly, Pfizer
Speaker’s Bureau: AstraZeneca, Forest, Pfizer
Eduard Vieta
GlaxoSmithKline, Janssen-Cilag
Consultant: AstraZeneca, Bristol-Myers Squibb, Eli Lilly, GlaxoSmithKline,
Janssen-Cilag
John Walkup
Grant/Research Support: Abbott, Lilly, Pfizer
Consultant: Lilly
Speaker’s Bureau: Janssen, Lilly, Pfizer
Stephen Warren
Other, Chair, SAB: Seaside Therapeutics
Dean Wong
Grant/Research Support: Acadia, Eli Lilly, Janssen, McNeil, Merck, Pfizer,
Phillip Morris
Consultant: AstraZeneca, Aventis, Eli Lilly, Janssen, McNeil, Merck, Pfizer,
Pharmacia, Sumitomo
183
Appendix 2006.qxp
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7:48 AM
Page 184
The following individuals had nothing to disclose:
Caleb M. Adler
Roger Albin
Susan Andersen
Stewart A. Anderson
Paul Andreason
Eva S. Anton
Ben A. Bahr
Vaishali P. Bakshi
Ruben Baler
Ben Barres
Jill B. Becker
Francesco Benedetti
Karen Berman
Thomas Biederer
Randy Blakely
Michel Bouvier
Linda Brady
David Brent
Andres Buonanno
M. Catherine Bushnell
Pamela D. Butler
Joseph Buxbaum
Patrizia Caldirola
Marc G. Caron
Cameron S. Carter
Dennis Charney
Jin-Chung Chen
Jingshan Chen
Jonathan D. Cohen
Lisa H. Conti
Gabriel Corfas
Rebecca Craft
Joseph F. Cubells
David J. Cutler
Deepak Cyril D'Souza
Kenneth Davis
Michael Davis
Michael Dean
Melissa P. DelBello
Edward Domino
Daniel Dorsa
Jing Du
Laura L. Dugan
Howard Eichenbaum
Ezekiel Emanuel
Susan Essock
Christopher Evans
Joram Feldon
Anna Francesconi
Ellen Frank
John Gabrieli
Albert Galaburda
Samuel John Gatley
Elliot S. Gershon
John H. Gilmore
Jay Gingrich
Paul W. Glimcher
Steven R. Goldberg
Terry Goldberg
David Goldman
James Goldman
Jack M. Gorman
Todd Gould
Steven Grant
Michael F. Green
Maureen K. Hahn
Ronald P. Hammer
James Harris
Stephan Heckers
Markus Heilig
Fred J. Helmstetter
James Dee Higley
Bartley G. Hoebel
William Horan
Z. Josh Huang
Robert Innis
Daniel C. Javitt
Sandra H. Johnson
Peter Kalivas
Julie A. Kauer
Hans Keirstead
Kwang-Soo Kim
Peter S. Klein
George F. Koob
184
Appendix 2006.qxp
11/17/05
7:48 AM
Page 185
Thomas Kosten
John Harrison Krystal
Cary Lai
Ruth Lanius
Amanda Jayne Law
Ellen Leibenluft
Sarah Leibowitz
Vance Lemmon
Pat Levitt
Michael Lewis
Barbara K. Lipska
Raye Litten
Edythe D. London
David M. Lyons
Pierre Magistretti
Steven Maier
Robert Malenka
Robert Malison
Shaila Mani
Husseini Manji
Kelsey Martin
Susan K. McConnell
Ronald McKay
Read Montague
Anne Z. Murphy
Jaap Murre
Vincent Mutel
Toshitaka Nabeshima
John F. Neumaier
Patricio O'Donnell
Valerie Olson
Paul H. Patterson
Jane Pearson
Laura Peoples
Srinivasan S. Pillay
Daniel Pine
Diego A. Pizzagalli
Jonathan Pollock
Maurizio Popoli
Gregory J. Quirk
Judith L. Rapoport
Scott L. Rauch
A. David Redish
Elliott Richelson
Victoria Risbrough
Angela Roberts
Terry Robinson
Lorna Role
Donald Rosenstein
Bryan L. Roth
Peter Scheiffele
Peter Schmidt
Yavin Shaham
Philip Shaw
Anantha Shekhar
Larry J. Siever
David Silbersweig
Rajita Sinha
Rainer Spanagel
Lalit Srivastava
Dietrich Stephan
Jamie Talan
David A. Talmage
Todd E. Thiele
Steven A. Thomas
Andrea Tone
Bruce Trapp
Hiroshi Ujike
Leslie G. Ungerleider
Maarten van den Buuse
Marquis Vawter
Frank Vocci
Nora Volkow
Franz X. Vollenweider
Mark von Zastrow
Cynthia Shannon Weickert
David Weinshenker
Friedbert Weiss
Susan Weiss
Lois Winsky
Ruth I. Wood
185
Appendix 2006.qxp
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7:48 AM
Page 186
Jim Woodgett
Kiyofumi Yamada
Rachel Yehuda
Larry James Young
James P. Zacny
George S. Zubenko
Jon-Kar Zubieta
186
Appendix 2006.qxp
11/17/05
7:48 AM
Page 187
The following participants intend to discuss an unapproved/investigative
(“off-label”) use of a product:
Susan Andersen
Paul Andreason
Steven Arnold
Ruben Baler
William Bunney, Jr.
H. Donald Burns
M. Catherine Bushnell
Joseph Buxbaum
William Carpenter
Dave Ceryak
Kiki Chang
Joseph F. Cubells
Michael Dean
Edward Domino
Ezekiel Emanuel
Susan Essock
Lars Farde
Colin Fish
Richard Frank
Paul Gaylo
Ira Glick
Guy M. Goodwin
Anthony Grace
Steven Grant
Michael F. Green
Heinz Grunze
Markus Heilig
Jonathan Javitch
Dilip V. Jeste
Ned Kalin
Peter Kalivas
Ira Katz
Hans Keirstead
Terrence Ketter
Donald Klein
Hartmuth Kolb
Thomas Kosten
John Krystal
Raye Litten
Antony Loebel
Husseini Manji
Athina Markou
Barbara J. Mason
Christopher J. McDougle
Joseph McEvoy
Ann C. Neale
David Nutt
Charles O’Brien
Jane Pearson
Daniel Pine
Jonathan Pollock
Murray Raskind
Trevor W. Robbins
Donald Rosenstein
Barbara Rothbaum
Barbara Sahakian
Alan Schatzberg
Peter Schmidt
Lon S. Schneider
Larry J. Siever
Thomas J. Spencer
Stephen Strakowski
Robert Swift
Pierre N. Tariot
Frank Vocci
John T. Walkup
Dean F. Wong
187
Appendix 2006.qxp
11/17/05
7:48 AM
Page 188
Author Index
11/17/05
7:49 AM
Page 189
AUTHOR INDEX
Author Index
11/17/05
7:49 AM
Page 190
Author Index
11/17/05
7:49 AM
Abadia, Maria Castillo
Abel, Ted
153
Abelson, James L.
Abi-Dargham, A.
Abi-Dargham, Anissa
129
Acharya, Nayan V.
Ackenheil, Manfred
Adams, David
Adams, John
Addicott, M.A.
Addington, Anjene
Addington, Stephanie
Adinoff, Bryon
Adler, Cal
Adler, Caleb
Adler, Caleb M.
Afari, Niloo
Aghajanian, George K.
Ahlbrand, Rebecca
Ahmed, Saeed
Ajilore, Olu
Akbar, Natkai
Akbarian, Schahram
Akil, Huda
145
Akpor-Mensah, Rostian
Alagbe, Oyetunde
Albers, Lawrence
Albin, Roger
Alce, Guilna
Alexopoulos, George
Alia-Klein, Nelly
Allen, D. Radant
Allen, Albert J.
Allen, Lesley A.
Allen, Nick
Almasy, Laura
Alonso, Angelique
Alonso, Richard
Alper, Kenneth
Alpert, Jonathan E.
Alphs, Larry
Alreja, Meenakshi
Page 191
122
24, 126,
Altar, C.
Altar, C. A.
Alvarez, E.
Amato, David
Ameli, Rezvan
Amiel, Jonathan M.
Amsterdam, Jay D.
Anagnostou, Evdokia
Anand, Amit
Andersen, Susan L.
Anderson, Berry
Anderson, Carl M.
Anderson, George
Anderson, George M.
Anderson, Stewart
Anderson, Susan
Andreason, Paul
Andrews, Glenn D.
Anggadiredja, K.
Angstadt, Michael
Angstadt, Mike
Ansorge, Mark S.
Anthony, James C.
Anton, Eva
Appel, James
Apud, J.
Apud, Jose A.
Arango, Celso
Arango, Victoria
Arce, Estibaliz
Archer, Stephen
Arciniegas, David B.
Ardekani, Babak A.
Arias, Robert
Ariely, Dan
Armbruster, Blaine
Armitage, Roseanne
Arnold, Paul
Arnold, Paul D.
Arnold, Steven
Arolt, Volker
Arora, Sanjay
Arrillaga-Romany, I. C.
Artaloytia, J. F.
Artymyshyn, Roman P.
106
118
68, 128,
95
109
99, 128
94
106
124
143
91
117, 144
56
94, 126
143
129
135
122
94
116
99
93, 97,
101
153
148
66
116, 138
94
111
147
108
98
138
105
99
121
107
93
100
153
191
24
100, 135
141
97
146
137
142
114, 115
116
91, 141
104
134
145
114
32
97
38, 49
108
137
108
137
98
91
82
152
151
116
100
139
139
122
139
134
90
117
153
94
27
95
82
98
109
100
100
96
Author Index
11/17/05
7:49 AM
Asberg, Marie
Ascher-Svanum, Haya
103, 128
Aschmies, Susan
Ashby, Charles
Ashford, J. W.
Ashley-Koch, Allison
Ashtari, Manzar
Ashton, David
Aston, Christopher
Atchinson, Kevin P.
Ator, Nancy
Attarbaschi, Trawat
Attner, Michelle
Atz, Mary E.
Augustyns, Ilse
Awad, A. G.
Axelson, David
Baare, William
Bachtell, Ryan K.
Badawy, A.A-B.
Bahr, Ben
Bahr, Ben A.
Bailer, Ursula F.
Bain, Earle
Baker, David
Baker, Glen
Baker, Ross A.
Baker, Sherryl
Bakshi, Vaishali
Baldessarini, Ross J.
Baler, Ruben
Ballinger, Dennis
Banerji, MaryAnn
Bannai, Makoto
Bannet, Yair
Barbano, PaoloEmilio
Barch, Deanna
Barefoot, John
Barker, Eric L.
Barnett, Alan S.
Barot, Sabiha
Barr, Christina S.
109, 113, 135
Barranco, Eva
Page 192
125
100,
Barres, Ben
Barrett, Andrew C.
Barrett, James E.
Barrett, Sean P.
Barrett, Thomas B.
Barros, Tanya
Barry, Audrey
Bartko, John
Barzman, Drew H.
Baskys, Andrius
Baucum, Anthony J.
Bauer, Jochen
Bauer, Michael
Bauer, Theresa
Baumann, Michael H.
Baxter, Lewis R.
Bayazitov, Ildar T.
Bazinet, Richard P.
Bear, Mark
Beard, Laura
Bearden, Carrie
Beasley, Jr., Charles M.
Becker, Carl
Becker, Jill
Becker, Kevin G.
Beebe, Katherine L.
Beesdo, Katja
Begleiter, H.
Beguin, Cecile
Belfer, Inna
Belknap, John K.
Bell, Richard L.
Beltaifa, Senda
Belzung, Catherine
Bendle, Scott
Bendor, Jacob T.
Benedetti, Francesco
Beneyto, Monica
Benkelfat, Chawki
116
Bentin, Shlomo
Berga, Sarah L.
Bergeron, Richard
Berghorst, Lisa
Berghorst, Lisa H.
90
148
89
133, 146
151
100
150
90
148
145
153
145
109
101
117
119
91
106
77
108
116, 118
95
101
122
100, 152
92
64
95
80
103
114
94
143
117
139
133, 146
91
137
114
92, 95,
99
192
65
91
146
113
149
120
106
100
94
153
107
98
95
151
97
143
153
154
73
144
140
95, 126
138
43
155
106
95
134
97
125
134
135
101
90
152
134
76
101
95, 113,
102
138
95
142
117
Author Index
11/17/05
7:49 AM
Bergman, Jack
Berman, Karen
Berman, Karen F.
Berman, Robert M.
Berman, Steven M.
Berney, Alexandre
Bernotas, Ron
Berns, Gregory S.
Berrettini, Wade
Bertisch, Hilary C.
Berton, Olivier
Bescholt, Anita J.
Best, Susan E.
Betensky, Julia
Bethea, Cynthia L.
Beyer, Chad
Beyers, Karen
Bhaskar, Kolachana S.
Bhattacharjee, Abesh
Bi, Wenzhu
Bidesi, Anup
Bidwell, L. Cinnamon
Biederer, Thomas
Biederman, Joe
Biederman, Joseph
Biemans, Barbara
Bierut, L.
Bikker, Angela
Bilder, Robert
Bilder, Robert M.
Binder, Elisabeth B.
Binesh, N.
Birell, Claire
Birkett, Melissa A.
Birmaher, Boris
Bissette, Garth
Bizot, Jean-Charles
Bjork, James
Blackburn, Thomas P.
Blair, James
Blakely, Randy
Blakely, Randy D.
Blanchard, John
Blanco, Carlos
Blasey, Christine
Page 193
92, 126
68
152
96
95, 138
95
109
138
124
103
115
123
91
151
106
148
108
116
139
139
142
102
65
122
118
100
134
145
107, 124
106, 151
92
94
109
142
117, 125
89
121
136
96, 144
99
78
115
103
123
106
Blasi, Giuseppe
Blazer, Dan G.
Blazer, Daniel
Blendy, Julie A.
Blier, Pierre
Bloch, Michael H.
Block, Thaddeus
Blumberg, Hilary
Bohning, Daryl
Boone, Ericka
Borba, Christina P.
Borckardt, Jeffrey J.
Borowsky, Beth
Bose, Anjana
Bosetti, Francesca
Bossie, Cyndi
Bossie, Cynthia A.
Bottiglieri, Teodoro
Bouvier, Michel
Bowden, Charles
Bowie, Christopher R.
Bowlby, Mark
Bowman, L.
Boyce-Rustay, Janel M.
Boyle, Maureen
Bradley, Brendan P.
Brady, Linda
Braff, David
102
Braff, David L.
Braff, DL
Brambilla, Paolo
Branch, Craig
Branch, Sarah
Branchek, Theresa
Branchek, Theresa A.
Branchey, Marc
Brann, Jessica H.
Brannan, Stephen
Braun, Miriam
Breeder, Christopher
Breeze, Janis L.
Breier, Alan
Breier, Michelle
Brennan, Julie
193
116, 138
89
123
123
95, 96
155
106
56
131
120
127
106
101
94
153
104, 105
98, 101
101
33
122
105
109
131
93
104
96
39
49, 101,
105, 129
102
140
103
103
70
96, 144
92
98
143
98
143
118
40, 103
149
148
Author Index
11/17/05
7:49 AM
Brennan-Krohn, Thea
Brennum, L.
Brent, David
Brent, David A.
Bresnahan, Michaeline
Briggs, Hedieh
Britton, Jennifer C.
Brodsky, Beth S.
Brodsky, Marc D.
Brody, Arthur L.
Brotman, Melissa A.
Brown, Alan S.
Brown, E. Sherwood
Brown, Eileen
Brown, Gregory G.
Brown, Hendricks
Brown, John
Brown, Justin
Brown, Lawrence S.
Brown, Morton B.
Brown, Walter
Brown, Kyle
Brumbach, Barbara H.
Brummett, Beverly
Brunelle, Caroline
Brunet, Alain
Brutsche, Nancy
Bryan, Holly S.
Bucholz, K.
Buchsbaum, Monte
Buchsbaum, Monte S.
Buchwald, Dedra
Buckholtz, Joshua
Buckholtz, Joshua W.
152
Bueller, Joshua
Buga, Adriana
Buitelaar, Jan
Bukstein, Oscar G.
Bulik, Cynthia M.
Bullich, S.
Bunney, William
Bunney, William E.
Bunt, Gregory
Buonanno, Andres
Page 194
119
150
49, 117
125
101
106
137
125
92
143
96
101
144
99
117
145
120
98
92
146
107
103
99
133, 146
113
96
146
126
134
140
138
143
102, 140
116, 141,
Burdick, Katherine E.
Burk, Gary M.
Burmeister, Margit
145
Burns, Donald
Burroughs, Eliza
Bustillo, Juan R.
Butler, Pamela
Butler, Pamela D.
Butterfield, Marian I.
Butters, Meryl A.
Buxbaum, Joseph D.
Buydens, Laure
Byerley, Bill
Bymaster, Frank
Bystritsky, Alexander
Cabrera, David M.
Cadenhead, Kristin
Cadenhead, KS
Cagliero, Enrico
Caine, S. B.
Caine, Simon B.
Calabrese, Joseph
Calabrese, Joseph R.
Caldirola, Patrizia
Caleo, Sue
Calkins, ME
Calkins, Monica E.
Callaghan, John T.
Callicott, Joseph
Callicott, Joseph H.
116, 127, 138, 141, 152
Callicott, Joseph S.
Campbell, Bryan J.
Canive, Jose M.
Cannon, Dara M.
Canuso, Carla M.
Cao, Jianjing
Caparelli, Elisabeth C.
Capece, Julie A.
Capuron, Lucile
Carballo, Juan J.
Carlezon, William
Carlezon, William A.
136
138
149
48
140
107
141
76
145
134
82
194
102, 132
105
96, 119,
39
95
102
75
102
89
124
23, 132
92
124
98
96
154
101, 102
102
127, 152
91
92
122, 144
146
70
104
102
147
98
140
90, 102,
141
142
130
96
98, 124
134
111
108
109, 138
135
97
97, 124,
Author Index
11/17/05
7:49 AM
Carlson, Gabrielle
Carlson, Janice
Carlson, Paul
Carlson, Robert
Carlson, Susan E.
Caron, Judy
Caron, Marc
Carpenter, David
Carpenter, Linda
Carpenter, Linda L.
Carpenter, William
Carroll, F. I.
Carson, Richard E.
Carson, William
Cartagena, Preston
Carter, Cameron
Carvalho, John P.
Cassano, Hope L.
Castellanos, F. Xavier
Caster, Joseph M.
Castillo, Desiree
Castro, Mariana Pereira
Catafau, Ana
Cato, Margaret A.
Cavazzoni, Patrizia A.
Caviness, Verne S.
Cecil, Kim
Cecil, Kim M.
Cepeda, Carlos
Ceryak, Dave
Cha, Joo H.
Chang, Kiki
Chang, Lin
Chang-Gyu Hahn
Chaplin, William
Chappell, Amy S.
Chappell, Phillip B.
Charney, Dennis
Charney, Dennis S.
Chau, David T.
Chen, Bin
Chen, Gang
Chen, Guang
Chen, Heidi
Chen, Jin-Chung
Page 195
122
151
146
91
122
97
41, 60
140
145
114
40
112
136, 139
130
145
45
114
102
117
112
152
105
141
117
95
118
117
126
108
38
134
56, 97
138
82
114, 115
107
106
74
125, 146
111
109
120, 141
97
144
51
Chen, Jingshan
Chen, Qiang
Chen, Robert
Chen, Scott A.
Chen, Stanford
Chen, Ying
Chen, Yue
Chen, Yuejin
Chen, J.
Chengappa, K.N. Roy
Childs, Emma
Chin, Ronald B.
Cho, William
Choi, Sang-Ho
Chong, Rachel
Choudary, Prabha V.
Chourbaji, Sabine
Chowdari, Kodavali V.
Christensen, Jon
Chua, Hannah F.
Chue, Pierre
Chui, Helena
Church, Timothy S.
Ciccone, Patrick E.
Clark, Janet
Clasen, Liv
Clauw, Daniel
Claycomb, Robert
Clinton, Sarah
Coccaro, Emil F.
137
Cody, Heather
Cohan, Jeannette
Cohen, Bruce M.
Cohen, Caroline
Cohen, Jonathan
Cohen, Miriam
Cohen, Ronald A.
Colantuoni, Carlo
Cole, Derek
Collins, Daphne
Comer, Sandra D.
Comery, Thomas A.
Compton, Wilson M.
Confer, Andrea L.
195
41, 116
116, 152
103
92
151
105
102
108
151
143
93
150
103
153
146
145
120
147
139
118
150
89
121
123
97
105, 115
46
108
97
108, 117,
116
117
97, 124
121
52
100
136
155
109
155
112
90
92
138
Author Index
11/17/05
7:49 AM
Conley, Rachel
Conley, Robert
154
Conley, Robert R.
Connor, Kathryn M.
Constable, R. T.
Conti, Alana C. C.
Conti, Lisa
Conway, Kevin P.
Cook, Edwin H.
Cook, Glen A.
Cooper, Thomas
Cooper, Thomas B.
Cooperberg, Mark D.
Copeland, Paul M.
Coplan, Jeremy
Coplan, Jeremy D.
Corcoran, Cheryl
Corfas, Gabriel
Correia, Stephen
Correll, Christoph U.
Corrigan, Brian
Corrigan, Mark
Corripio, I.
Cortese, Bernadette M.
Corya, Sara
Coryell, Bill
Costa, Erminio
Coste, Sarah
Cotton, Aronica
Cottone, Lisa A.
Covell, Julie
Covington, Herbert E.
Cox, David R.
Coyle, Joseph
Craig, Douglas A.
Craiglow, Britt
Crandall, David
143, 152
Creson, Thomas
Crissman, Alicia M.
Croft, Rodney J.
Crosson, Bruce A.
Crow, Scott J.
Cruz, Rick
Page 196
97
98, 103,
Cryan, John F.
Csernansky, John
Cubells, Joseph
Cubells, Joseph F.
Cubero, Pedro
Cui, Lihong
Cummings, Jeffrey
Cunningham, Kathryn A.
Cunningham, Miles
Cunningham, Miles G.
Cutler, David
Czachowski, Cristine
Czeisler, Charles A.
D’Souza, Deepak
Daniel, David G.
Danus, M.
Darwin, C.
Das, Saumitra
Daskalakis, Zafiris J.
Davenport, Nicholas
Davidson, Jonathan
Davidson, Jonathan R.
Davidson, Michael
Davis, John
Davis, Kenneth
Davis, Kenneth L.
140
Davis, Michael
Davis, Nicole Y.
Daws, Lynette
Daws, Lynette C.
De Kloet, Carien
De Leon, Mony J.
De Wit, Harriet
Deadwyler, Samuel
Dean, Michael
Deas, Deborah
DeBattista, Charles
Deckert, Juergen
Deckert, Jurgen
Decobert, Michel
Deep-Soboslay, Amy
Degenhardt, Elisabeth
DeKosky, Steven T.
139
128
97
104
123
64
92
134
107
129, 139
135
146
127
126
114, 137
128, 130
63
119
132
106
97
141
123
151
124
105
142
137
111
120
124
103
132
96, 144
155
130, 131,
97
125
138
117
107
107
196
54
72
31
92
100
123, 124
91
111
25
97
86
92
109
77
100
141
94
90, 138
103
152
97
123
101
100
89
23, 132,
84
109
93
107
145
44, 90
93, 134
91
29
93
106
98
93
121
102
99
124, 138,
Author Index
11/17/05
7:49 AM
Delahanty, Ryan J.
DelBello, Melissa
DelBello, Melissa P.
117, 126, 144
DeLisi, Lynn E.
DeLory, Michael
Demitrashvili, Marina
Dence, Carmen S.
Denslow, Stewart
Derby, Eric
DeRosse, Pamela
Detke, Michael J.
Deutch, Ariel
DeVane, Lindsay
Devous, Michael D.
Di Martino, Adriana
Diamond, Pamela
Dick, D.
Dickstein, Daniel P.
Dieterich, Megan E.
Diksic, Mirko
DiNieri, Jennifer A.
Dittman, Ralf
Diwadkar, Vaibhav A.
Dobie, DJ
Dobie, Dorcas J.
Dobkin, Roseanne D.
Docherty, John
Dombrowski, Philip
Dominguez, Juan M.
Domino, Edward
Domschke, Katharina E.
Donalds, Rachael
Donati, Robert
Donovan, Jennifer
Dorsa, Daniel
Dossenbach, Martin
Dougherty, Donald M.
Douglas, Louisa
Drabant, Emily M.
Dreher, Jean-Claude
Dremencov, Eliyahu
Drevets, Wayne C.
120, 123, 125, 138
Driesen, Naomi R.
Page 197
115
56, 122
94, 103,
DSouza, Deborah N.
95, 107
Du, Jing
69, 98
Dube, S.
131
Dubocovich, M. L.
154
Dubocovich, Margarita 76
Dugan, Laura
34
Dulawa, Stephanie C.
98
Dumalska, Iryna
153
Duman, Ronald S.
153
Dunlap, Steven
117
Dunlop, John
126, 148
Dunn, Laura B.
106
Dunner, David
99
Dunner, David L.
98
Durkin, Margaret
96
Duytschaever, Hilde
100
Dwivedi, Yogesh
98, 125,
154
Dworakowski, Diana
117
Dwork, Andrew
126
Eastvold, Angela
102
Eckelman, William C.
139
Edenberg, H.
134
Edwards, Robert H.
154
Eerdekens, Els
130
Eerdekens, Marielle
127, 130
Egan, M.
151
Egan, Michael
152
Egan, Michael F.
90, 102,
116, 138, 141, 149, 150, 152
Ehlers, Cindy L.
93, 136
Ehrlichmen, Richard S. 149
Eichenbaum, Howard
59
Eidelberg, David
90
Eiduson, Samuel
96
Eisen, Seth A.
142
Ekholm, Jenny
129
Ekholm, Jenny M.
132
El Mansari, Mostafa
96
Elliott, Mark
147
Ellis, Jamey
132
Ellis, Steven P.
125
Elman, Igor
117
Eltayb, Amani
150
Emanuel, Ezekiel
40
103
92
138
138
131
100
102
98, 107
67, 97
103, 131
91
117
152
134
117
118
95, 116
97
122, 151
117, 128
102
147
98
104
155
98
51
98
97
98
103
43
126
106
100
116
152
96
96, 118,
104
197
Author Index
11/17/05
7:49 AM
Engel, Sharon
Engelhart, Luella
Engelien, Almut
Enoch, Mary-Anne
Entsuah, Richard
Epperly, Garretson D.
Epping, Eric
Ereshefsky, Larry
Erickson, Kristine
118
Eriksson, Bo
Ernst, Monique
Ervin, John
Escamilla, Michael A.
Esposito, Giuseppe
Esposito, Michael
Esser, Steve K.
Essock, Susan
Estrada, Jose
Evans, Alan
Evans, Christopher
Evans, Karleyton
Evans, Ken
Evans, Simon J.
Evans, Suzette M.
Evins, A. Eden
Ewing, Sarah B.
Fabian, Sara
Faccidomo, Sara P.
Faison, Warachal E.
Fang, Liwei
Farabaugh, Amy H.
Farber, Robert
Farde, Lars
Faries, Douglas
Faustman, William O.
Fava, Maurizio
120, 126
Feder, Adriana
Feifel, David
Feldman, Ruth
Feldon, Joram
Feltenstein, Matthew W.
Ferguson, James M.
Fernandes, Prabhavathi
Page 198
97
107
98
136
99
154
116
152
26, 115,
Ferrarelli, Fabio
Ferris, Steven
Findling, Robert
Findling, Robert L.
Finger, Elizabeth
Fink-Jensen, Anders
Fisch, Hans-Ulrich
Fischer, Andre
Fischer, Grace
Fischman, Alan J.
Fish, Colin
Fisher, Alan C.
Fissell, Kate
Fitterling, Heidi
Fitzgerald, Daniel A.
137
Fitzgerald, Kate D.
Flagel, Shelly B.
Fleck, David E.
Fleckenstein, Annette
Flick, Rosemarie B.
Flor, Herta
Flores, Osvaldo
Floresco, Stan B.
Floyd, Bloom E.
Foltin, Richard W.
112
Ford, Judith
Ford, Judith M.
Ford, Lisa
Foroud, T.
Fountain, Sarah I.
France, Adrian K.
France, Charles P.
Francesconi, Anna
Francon, Dominique
Frank, Ellen
Frank, Guido F.
Frank, Guido K.
Frank, L.
Frank, Richard
Frankle, Gordon W.
Frankle, WG
Frazer, Alan
Frazier, Jean A.
104
142
89
105
139
126
132
55
105
105, 115
85
118
99
145
93
93, 120
112
153
94
89
153
93
106
39
100, 103
104
93, 97,
99, 137
104
140
35
94, 135
99
104
198
132
90
122
109, 146
99
92
143
154
123
134
39
108
141
137
108, 117,
118
93
99
107
97
120
97
94, 126
90
93, 111,
27
104
127, 130
134
103
93
93, 112
50
121
79
116
118
131
39
129
118
107
118, 151
Author Index
11/17/05
7:49 AM
Frederick, Blaise
Frederick, Blaise D.
Fredrickson, Barbara L.
Free, R. B.
Freed, William J.
Freedman, Robert
Freeman, Marlene P.
Freudenreich, Oliver
Friberg, Lars
Frick, Caroline
Friedman, Joseph I.
Frol, Alan B.
Fromm, Stephem
Frye, Mark A.
Fu, Dong-Jing
Fuchs, Rita A.
Funke, Birgit
Furey, Maura L.
Furman, Daniella
Fusco, Maureen
Fyall, Amber
Gable, Karissa L.
Gabrieli, John
Gadde, Kishore
Gagne, Gerard G.
Galaburda, Albert
Galit, Yovel
Gallagher, Paul
Gallelli, Kim
Galli, Aurelio
Gallitano-Mendel, Amelia
Galloway, Matthew
Galloway, Matthew P.
Galper, Daniel I.
Gandhi, Shilpa K.
Gao, Sujuan
Garlow, S.
Garlow, Steven J.
Gass, Peter
Gassmann-Mayer, C.
Gatley, Samuel
Gaylo, Paul
Gelenberg, Alan
Gelenberg, Alan J.
Gelernter, Joel
Page 199
117
134
140
154
155
132
99
105
119
143
89, 140
144
96
99
103
94
102
118, 120
152
89
111
115
59
109
114
37
102
100
97
93
104
102
118, 138
121
96
116
122
120
120
127
77
39
107
99, 122
140
Gemelli, Terry
Genius, Just
George, Mark S.
131
George, Tony P.
Georgieva, Lyudmila
Gerald, Christophe P.
Gerety, Lyle P.
Gerhardt, Greg A.
Gerig, Guido
Gerlach, Lauren
Gershon, Elliot
Geuze, Elbert
Geyer, Christopher
Geyer, Mark
142
Geyer, Mark A.
Gharabawai, Georges
Gharabawi, Georges
105, 107, 155
Gharabawi, Georges M.
Ghosh, Debashis
Ghuman, Harinder S.
Ghuman, Jaswinder K.
Giardino, Odessa
Gibbons, Robert D.
Gibbs, E. M.
Gibert, Stephen
Gibson, Brian
Giedd, Jay
105
Giedd, Jay N.
Giegling, Ina
Gil, Lucas
Gil, Mario
Gil, Roberto
Gilliam, T. C.
Gilmore, John
114
Gilmore, John H.
Gingrich, Jay A.
Ginter, P.
Giuffrida, Andrea
Glahn, David C.
Glaser, Paul E.
199
115
109
104, 106,
105
132
96, 144
124
154
114, 119
112
86, 124
119
136
36, 64, 72,
116
106
95, 104,
101, 124
96
107
107
101
145
148
106
103
37, 81,
115
109
122
98
129
134
26, 36,
115, 119
98
154
107
105
154
Author Index
11/17/05
7:49 AM
Page 200
Glass, Richard
38
Glass, Steven J.
107
Glassman, Alexander
38
Glenthoj, Birte
27
Glenthoj, Birte Y.
119
Glick, Ira
79
Glimcher, Paul
52
Glitz, Debra A.
123
Glover, Gary
104
Goate, A.
134
Godbout, Roger
147
Goeders, Nicholas E.
111
Goetz, Raymond
128
Goetz, Raymond R.
128
Goff, Donald C.
105, 127,
152
Gogtay, Nitin
27, 105
Gold, James M.
131
Gold, Philip
115
Goldberg, Jack
143
Goldberg, Steven
80
Goldberg, Steven R.
113
Goldberg, Terry
59, 90
Goldberg, Terry E.
116, 120,
150
Goldman, Aaron L.
120, 127,
141
Goldman, David
29, 58, 95,
109, 113, 116, 125, 129, 136, 137
Goldman, James E.
23
Goldman-Rakic, P. S.
104
Goldstein, David J.
107
Goldstein, Rita Z.
111
Golembo, Nicole
100
Goletiani, Nathalie V.
111, 114
Goltser-Dubner, Tanya
149
Golzer, Tanya
125
Gonsai, Kishor
112
Gonzalez, Gerardo
112
Goodman, M.
118
Goodman, Mark M.
112
Goodman, Wayne K.
120
Goodwin, Guy
48
Gordon, Joshua
25
Gordon, Joshua A.
120
200
Gorman, Jack
140
Gould, Georgianna G.
Gould, Todd
Gould, Todd D.
Grace, Anthony
Granholm, Eric L.
Grannemann, Bruce D.
Grant, Jon
Grant, Kathleen A.
Grant, Merida M.
Grant, Richard W.
Grant, Steven
Grauer, Steve
Gravel, Paul
Gray, May
Grayson, Dennis R.
Green, Alan I.
Green, Michael F.
Greenhill, Laurence
Greenspan, Andrew
Greenstein, Deanna
Greenstein, Dede
Greenwood, Tiffany A.
Greer, Tracy L.
Greisenegger, Erika
Greist, JH
Griebel, Guy
Griffith, Gayle
Grigoriadis, Dimitri E.
142
Grimm, Jeffrey W.
Grossman, Hillel
Gruber, Staci A.
Grunder, Gerhard
Grundt, Peter
Grunze, Heinz
Gu, Hongbin
Guidotti, Alessandro
Guilfoyle, David G.
Guimaraes, Angela
Gunderson, Erik
Gunduz-Bruce, H.
151
Gur, Eitan
40, 47,
107
60
121
42, 66
117
121, 145
119
113
119
152
52
126
95, 116
104
105
111
105
125
101
105
115
105
121
140
110
121
102
106, 121,
111
89
132, 137
119
91
48, 109
127
105
132
152
112
129, 148,
125
Author Index
11/17/05
7:49 AM
Page 201
Gur, Raquel
105
Gur, Raquel E.
147
Gur, Ruben
75
Gur, Ruben C.
128,
Gutierrez-Esteinou, R.
131,
Gwaltney, Chad
114
Gyulai, Laszlo
122
Hahn, Chang-Gyu
82
Hahn, Maureen
78
Haile, Colin N.
108
Hajianpour, Arash
140
Hall, Jerry A.
107
Hamer, Robert
127
Hamer, Robert M.
130
Hammer, Ronald
64
Hammer, Ronald P.
100
Hammonds, Michael
144
Han, Qiao
115
Handa, Robert J.
89
Haney, Margaret
111,
Hannigan, John H.
118
Hanson, Glen R.
107
Hao, YanLei
97
Harding, Richard
124
Hariri, Ahmad R.
138
Haroon, E
94
Haroutunian, Vahram
101,
132, 147
Harral, Erin
139
Harris, James
49
Harris, Thomas S.
91
Harrison, Boyd
126,
Harrison, P. J.
151
Hart, Carl
111
Hart, Carl L.
112
Hartmann, Annette
109
Harvey, John A.
109
Harvey, Phil
140
Harvey, Philip D.
105,
124
Haschke, Eric
101
Hasdemir, Mustafa
143
Hashemzadeh, Mehrtash 148
Hassan, Khader M.
111
Hassel, Stefanie
141
Hassman, Howard A.
Hastings, Ramin S.
Haubenreich, Kristen M.
Hawk, Josh
Hayashi, Kiralee M.
Hazelwood, Lisa A.
Hazlett, Erin A.
Heaton, Robert
Heberlein, Ulrike
Hebert, Chantal
Heckers, Stephan
Heerey, Erin A.
Hegerl, Ulrich
Heijnen, Cobi J.
Heilig, Markus
Heim, Christine
Heindel, Walter
Heinz, Andreas
Heitzeg, Mary
Helboe, L.
Hellweg, Rainer
Helmstetter, Fred
Hemmingsen, Ralf
Hen, Rene
120
Henck, Judith W.
Henderson, David C.
Henke, Bettina
Henn, Fritz A.
Henry, Brian
Henry, Shannan E.
Hensler, Julie G.
Herbener, Ellen
Herbert, Martha R.
Heresco, Uriel
Hermann, Carol
Hernandez, Olivia
Herremans, A. H. J.
Herringa, Ryan J.
Herscovitch, Peter
139
Hertel, Peter
Hesselbrock, V
Hesselink, Mayke
147
152
112
128,
148
106,
201
107
121
118
153
140
154
138
102
103
95
59
131
109
145
61
121, 153
98
136
119
150
120
84
119
90, 98,
98
127, 152
124
120
151
116
121
139
118
102
90
139
150
142
125, 136,
130, 150
134
150
Author Index
11/17/05
7:49 AM
Higley, J. D.
109, 113, 115
Higley, James
Higley, James D.
Hill, Rebecca
Hiranita, Takato
Ho, Beng-Choon
Ho, Shao-Hsuan
Hobbs, Katherine
Hockett, Richard D.
Hodge, Steven M.
Hodgkinson, Colin A.
Hoebel, Bartley
Hof, Patrick
Hoffmann, Robert
Hogarty, Gerald E.
Hoge, Jessica A.
Hohoff, Christa
Hokfelt, Tomas
Holcomb, Henry H.
Holick, Kerri A.
Holik, Alexander
Holland, Christine
Holland, Scott K.
Hollander, Eric
115
Hollon, Steven D.
Holmes, Andrew
Holston, Rachel E.
Holt, Richard
Holzman, Philip
Hommer, Daniel
Honea, Robyn
Honea, Robyn A.
Hooper-Wood, Christa
Hoptman, Matthew
Hoptman, Matthew J.
Horan, William
Horgan, Jennifer
Horner, Michael
Hortnagl, Heide
Houseknecht, K. L.
Houston, John
Howe, Meghan
Howell, Leonard L.
Page 202
92, 95,
Hrabe, Jan
Huang, Hsien-Sung
Huang, Xiaohong
Huang, Y.
Huang, Ying
Huang, Yiyun
Huang, Yung-yu
Huang, Z. Josh
Huber, Reto
Hudson, James I.
Hudson, R. L.
Huffaker, Stephen J.
Huganir, Richard
Hulette, Christine
Hulihan, Joseph F.
Hull, Elaine M.
Hunt, Rachel A.
Hustig, Harry
Hutson, Peter H.
Hwang, D-R
Hwang, Dah-Ren
Hyde, Christopher
Hyde, Thomas M.
155
Ice, Kathleen
Ichise, Masahiro
Indersmitten, Tim
Ingham, Mike
Innis, Robert
Insanally, Michele
Iskander, L.
Iudicello, Jennifer
Ivleva, Elena
Iyengar, Malini
Iyengar, Smriti
Jack, Blaine
Jacob, Suma
Jacobi, Frank
Jacobs, An
Jacobsen, J. S.
Jacobson, Ira M.
Jaenisch, Rudolf
Jaffe, Craig
Jagar, A.A.
Jagust, William
58
135
99
137
127
137
127, 141
103
118
137
53
140
94
128
124, 139
93, 98
144
129
98
145
152
94
26, 114,
119
93
109
131
102
92, 136
141
127, 141
123
103
132, 134
75
89
131
120
148
99
97
112
202
134
99
122
118
146
129
121
32
132
107, 108
154
127
73
89
143
98
100
104
97
118
129
117
102, 127,
103
96
128
104
39, 68
126
118
116
150
144
98, 107
137
115
95
104
90
109
115
112
106
89
Author Index
11/17/05
7:49 AM
Jalbrzikowski, Maria
Jamal, Mazan
Jardemark, Kent E.
Jarskog, L. F.
Jarvis, Kelly
Javitch, Jonathan
Javitt, Daniel
Javitt, Daniel C.
Jayathilake, Karu
Jennifer, Wilkerson
Jentsch, J. David
Jentsch, J. D.
Jeste, Dilip
Jeste, Dilip V.
Jiang, Lan
Jiang, Qin
Jina, Anil S.
Jochims, Anja
Johanson, Chris-Ellyn
Johnson, Brandy
Johnson, D. E.
Johnson, Kevin
Johnson, Sandra
Johnson, Steven
Johnson-Davis, K. L.
Johnston, Daniel
Jokinen, Jussi
Jomier, Matthieu
Jones, Doug
Jones, Douglas W.
Jones, Edward G.
Jones, Kenneth A.
Joshi, Sarang
Joyce, B. M.
Jurata, Jurata W.
Kadiyala, Sridhar
Kail, Melanie
Kalali, Amir H.
Kalin, Ned H.
Kalivas, Peter
Kalivas, Peter W.
Kamanna, Vaijinath
Kamel, Niveen
Kamens, Helen M.
Page 203
102
148
130
115
94
33
75
102, 132
108, 131
115
103
113
34, 62
106
115
123, 145
100, 152
119
136
144
148
131
38
105
107
148
125
119
140
137
145
96
119
154
100
90
133, 146
101
121, 142
57, 80
151
153
99
134
Kane, John
151, 154
Kane, John M.
127, 129, 132
Kanes, Stephen J.
Kanes, Steve
Kanwisher, Nancy
Kapur, Shitij
Karagille, Ayse T.
Karanian, David A.
Karatekin, Canan
Karson, Craig
Kashyap, Moti L.
Kasper, Siegfried
Katz, Jonathan L.
Kauer, Julie
Kaufman, Daniel
Kaufman, Marc J.
Kavalali, Ege
Kavelaars, Annemieke
Kaye, Walter H.
Ke, Yong
Keck, Martin
Keefe, Richard
Keenan, Kate
Kegeles, Lawrence S.
Kehoe, Priscilla
Keirstead, Hans
Keitner, G. I.
Keller, David
Keller, Martin B.
Kelley, Ann E.
Kelley, Mary E.
Kelly, Deanna L.
Kelly, Erin
Kelly, Michele
Kelsey, Douglas K.
Kelsoe, John
124
Kelsoe, John R.
Kendi, Mustafa
Kenna, George A.
Kenna, Heather A.
Kennedy, David N.
Kennedy, James
203
130, 148,
100, 102,
151
126
102
41
152
108
152
121
153
145
134
73
114
120, 134
115
145
116, 118
132
109
127
115
128, 129
108
23
122
103
122
135
147
128
149
126
108
86, 116,
149, 151
152
112
142
118
58
Author Index
11/17/05
7:49 AM
Kennedy, James L.
Kenny, Paul J.
Kent, Justine M.
Kentros, Clifford G.
Kerr, Natalie
Kersting, Anette
Kerwin, Lauren
Keshavan, Matcheri
Keshavan, Matcheri S.
140, 147
Ketchum, Katherine
Ketter, Terence
Ketter, Terence A.
Khadivi, Ali
Khan, Alea
Khan, Arif
Khan, Samir
Khanal, Mandar
Kieres, Artur K.
Kim, Dong-Wook
Kim, Jeansok J.
Kim, Kwang-Soo
Kimhy, David
Kimmel, Heather L.
Kingshott, Elesha
Kinkead, Becky
Kinon, B.
Kinon, Bruce
Kinon, Bruce J.
Kipp, Heidi
Kirkwood, Sandra Close
Kirov, George
Kirshner, Margaret
Kleber, Herbert
Klein, Daniel N.
Klein, Donald
Klein, Lauren
Klein, Nikolas
Klein, Peter
Kleinman, Joel E.
155
Kleinman, L.
Kletter, Kurt
Klock, Allan
Page 204
95
112
139
120
141
98
96
147
117, 128,
Klunk, William E.
139
Knable, Michael
Knadler, Mary Pat
Knoll, Allison T.
Koch, Paul
Kocsis, James H.
Koe, B. K.
Koek, Wouter
Kohler, Christian G.
Kohn, Philip
Kolachana, B. S.
141, 149, 150, 151
Kolb, Hartmuth
Kolko, David
Kolts, Russell
Konkel, Michael J.
Konradsson, Asa
Koob, George
Koob, George F.
Koola, Jejo
Kopajtic, Theresa
Korotzer, Andrew
Kosel, Markus
Kosik-Gonzalez, Colette
Kosten, Therese A.
Kosten, Thomas
Kosten, Thomas R.
Kostic, Dusan
Kowatch, Robert
144
Kowatch, Robert A.
Kozel, F. A.
Kozel, Frank A.
Kraemer, Helena C.
Kral, John G.
Kramer, Elisse
Kramer, J.
Kramer, Joel
Kramer, Larry
Kramer, Michelle
Krefetz, David G.
Kreilgard, M.
Krishen, Alok
Kristiansen, Lars V.
89
79
122
148
149
107
106
112
124
97
108
78, 97
128, 130
112
90
67
131
103, 128
100
140
103
132
90
130
122
38
136
145
60
102, 127,
131
145
108
204
124, 138,
104
98
124
152
122
148
112
128
152
90, 138,
39
125
107
96, 144
130
53, 61
134
131
134
94
143
101, 104
108
31
108, 112
130, 143
103, 122,
94, 99
104, 106
131
89
114
90
134
89
111
127, 130
107
150
126
128, 147
Author Index
11/17/05
7:49 AM
Kritz, Steven
Krupitsky, Evgeny M.
Krystal, John
Krystal, John H.
Kryzhanovskaya, Ludmila
Kucherlapati, Raju
Kuczenski, Ronald
Kuczora, Meaghan
Kugel, Harald
Kuhn, Cynthia
Kuhn, Cynthia M.
Kumar, A.
Kumaran, S.
Kumra, Sanjiv
Kuperman, S.
Kupfer, David J.
Kussmaul, Lucinda
Kyle, Kampman
Lacefield, Clay O.
Ladouceur, Cecile D.
Laeng, Pascal
Lahti, Adrienne
Lahti, Adrienne C.
Lai, Cary
Laird, Nan M.
Lal, Harbans
Lalonde, Justine K.
Lam, Francis
LaMantia, A. S.
Lambe, Evelyn K.
Lamberti, J. S.
Landinez, Johanna
Landry, Charles F.
Lanfranco, Marie F.
Langefeld, Carl
Lanius, Ruth
Lanzenberger, Rupert
Lara, Nathalie
LaRossa, Gina N.
Laruelle, M.
Laruelle, Marc
129
Lattal, K. Matthew
Lavin, Antonieta
Lavretsky, Helen
Page 205
92
112
32
104
122, 151
102
149
149
98
146
109, 112
94
94
151
134
141
91
136
120
141
100
100
129
82
107
107
107
152
115
129
105
144
135
111
124
74
145
122
138
118
26, 128,
Law, Amanda
Lawson, David H.
Le Foll, Bernard
Le Guisquet, A.M.
Le Melledo, Jean-Michel
Leckman, James
Leckman, James F.
Lee, Buyean
Lee, David Y.
Lee, Ho-Joo
Lee, Royce
Lee, Sang Y.
Lee, Soon Y.
Leherecy, Stephane
Lehrmann, Elin
Leibenluft, Ellen
117, 142
Leibowitz, Sarah
Leman, Samuel
Lemire, Andrew
Lemmon, Vance
Lenane, Marge
Lenartz, Doris
Lencz, Todd
151
Lenox, Robert
Lenroot, Rhoshel
Leon, Andrew
Leow, Alex D.
Lerch, Jason
Lerer, Bernard
Lesage, Anne
Lesser, Martin
Leung, Hoi-Chung
Levant, Beth
Lever, John R.
Levin, Edward D.
Levine, Ari
Levine, Louise
Levine, Michael S.
Levitt, Pat
Levy, Mya E.
Lewis, David
Lewis, David A.
Lewis, Lydia
153
108
89
205
63
138
113
90
122
155
140
113
97
154
108, 137
138
134
152
155
45, 96,
53
90
100
50
105
143
102, 129,
101
115
105
140
105
125, 149
54
148
104
122, 135
134
129
94
108
108
83
151
32
147
49
Author Index
11/17/05
7:49 AM
Lewis, Michael
Lewis, Shon
Lewis, Stephen F.
Lewy, Alfred
Leyton, Marco
116
Li, Jun
Li, Ting-Kai
Li, Wei
Li, Xin-Min
Li, Yu
Li, Z.
Li, Zhen
Li, Zhu
Liang, Shi
Libby, Anne M.
Liberzon, Israel
Lieberman, Jeffery A.
Lieberman, Jeffrey
129
Lieberman, Jeffrey A.
Lieberman, Joseph A.
Liebowitz, Michael
Lifschytz, Tsuri
Light, Gregory
Light, Gregory A.
Lim, Kelvin O.
152
Lim, Pilar
Lin, Daniel
Lin, Ping
Lin, Qian
Lin, Weili
Lindell, Stephen
Lindell, Stephen G.
Lindenmayer, J-P
Linnoila, Markku
Lipschitz, Alan
Lipska, Barbara
Lipska, Barbara K.
Lipsky, Robert
Lisanby, Sarah H.
Litten, Raye
Littleton, John
Liu, Amy
Page 206
53
55
130
76
95, 113,
Liu, Danni
Liu, Liyan
Liu, Yijun
Livni, Eli
Locklear, Julie
Loebel, Antony
131, 144, 148, 154
Lombardo, Illise
Lominac, Kevin D.
London, Edythe
London, Edythe D.
Looney, Christopher
Lopresti, Brian J.
Lorell, Beth
Loughead, James
Louie, Pearl M.
Louis, Caroline
Love, Raymond C.
Low, Nancy C.
Lowe, Mark J.
Lu, Bai
Lu, Brett Y.
Lu, Xueling
Luber, Bruce
Luckenbaugh, David
Lucki, Irwin
Lukas, Scott
Lukas, Scott E.
Lund, Trent D.
Lyons, David
Ma, Yilong
Ma, Zhongze
Maas, Luis C.
Macciardi, Fabio
MacDonald, Jessica
Mack, David
Mack, Wendy J.
Mackeprang, Torben
MacKillop, James
Madayag, Aric
Madras, Bertha K.
Maggin, Jeremy
Magistretti, Pierre J.
Magolda, Ron
Mah, Linda
145
135
120
129
116
151
149
108
109
145
106
114
55, 127,
89, 115
130
123
125
101
129, 149
113, 134,
127
122
146
148
114
115
92, 113
149
92
144
41, 81
127
95
123
61
61
135
206
109
101
120
134
95
105, 129,
144
151
51, 138
95, 113
114
124, 139
148
128
127
121
128
123, 124
116
98
130
139
123
125, 146
123
117
134
89
74
90
97
134
149
130
103
89
119
114
101
134
94
23
148
118
Author Index
11/17/05
7:49 AM
Maharajh, Keeran
Maidment, Karron M.
Maier, Steven
Mailman, Richard
Mailo, Kevin
Majcher, Magda
Majumdar, Sonalee
Makris, Nikos
Makriyannis, Alexandros
Malaspina, Dolores
Malberg, Jessica
Malberg, Jessica E.
Malenka, Robert
Malhotra, Anil
Malhotra, Anil K.
132, 151
Malison, Robert
Mallinckrodt, CH
Mallinger, Alan G.
Maloney, Thomas
Manaois, Meghan
Mandel, Francine
Mandelkern, Mark A.
Maness, Patricia F.
Mani, Shaila
Manji, Husseini
123
Manji, Husseini K.
121, 146
Mann, J. J.
Mann, J. John
Mannaert, Erik
Mansbach, Hank
Manschreck, Theo
Mao, Lian
Mao, Xiangling
Mao, Xiangling S.
Marangell, Lauren
Marchuk, Douglas A.
Marcovina, Santica M.
Marcus, Monica M.
Marcus, Ronald
Marder, Stephen
Marder, Stephen R.
Marenco, Stefano
Page 207
148
143
36
104
122
103
149
118
77
128, 130
126
123
73
130
102, 129,
31
110
140
111
111
144
95
115
43
60, 83, 98,
23, 97,
135, 139
121,125
119
91
105
107
128
137
122, 123
109
149
130
131, 152
152
130, 132
137
207
Mark, Black
Mark, Slifstein
Markou, Athina
112, 135
Markowitz, John
Marmar, Charles
Marquis, Karen
150
Marquis, Karen L.
Marsh, Abigail
Marsh, D.M.
Marsh, Harold M.
Martell, Bridget
Martin, Kelsey
Martin, Kimberly
Martinez, James
Martis, Brian
Martone, Robert
Marx, Christine E.
Masand, Prakash S.
Masliah, Eliezer
Mason, Barbara
Massari, Carla
Massimini, Marcello
Mathalon, Daniel H.
Mathew, Sanjay J.
Mathew, Shiny V.
Mathias, C.W.
Mathis, Chester
Mathis, Chester A.
138, 139
Mattay, Venkata S.
116, 120, 127, 138, 140,
Matute, Melissa
Maullin, Nathalie
Maxwell, Christina
Mayer, Emeran
Mayer, Emeran A.
Mayes, Linda C.
Mayhew, Michael B.
Maynard, Melissa
Mazandarani, Hossein
Mazar, Nina
McBride, William J.
McCall, W. V.
101
129
35, 54,
103
125
90, 126,
148
99
106
118
112
65
130
123
137
90
89
123
108
61
151
132
104, 130
137
127
106
138
116, 124,
90, 102,
141, 152
149
136
149
46
138
140
150
115
126
117
135
97
Author Index
11/17/05
7:49 AM
McCarthy, Timothy
McCloskey, Michael S.
McClure, Erin B.
McCohana, Claire W.
McConnell, Susan
McCormack, Joanne
McDonald, Heather
McDougle, Christopher
McDougle, C. J.
McElroy, Susan
McElroy, Susan L.
McEvoy, Joseph
McEvoy, Joseph P.
McFarr, Lynn Marcinko
McGlashan, Thomas H.
McInnes, Lynne A.
McInnis, Melvin
McKay, Ronald D.G.
McKelvey, George M.
McKinstry, Robert
McLaughlin, Ryan J.
McMahon, Francis
McMahon, Robert P.
McNamara, Robert K.
Meador-Woodruff, J. H.
147
Medori, Rossella
Meichle, Sean P.
Meigs, James B.
Meitinger, Thomas
Melendez, Gilia
Melhem, Nadine
Mello, Andrea F.
Mello, Marcelo F.
Mello, Nancy K.
113, 114
Meloni, Edward G.
Meltzer, Carolyn C.
124, 138, 139
Meltzer, David
Meltzer, David O.
Meltzer, Herbert Y.
Mendelowitz, Alan
Mendelson, Jack H.
114
Page 208
39
108, 117
142
116
37
148
99
83
115, 151
108
107
55, 127
130
128
130
131
124
30
118
139
94
124
128
135
101, 128,
Meng, Fan
145
Menza, Matthew
98
Merchant, Kalpana
147
Meredith, Charles W.
112
Merikangas, Kathleen R. 123, 124
Merzenich, Michael
152
Meulman, Ellen
145
Meyenberg, Naxhielli
105
Meyer, E. T.
134
Meyer, Jonathan
131
Meyer, Roger
38
Meyer-Gomes, Katrin
129
Meyer-Lindenberg, A.
29, 68, 90,
120, 138, 141
Meyer-Lindenburg, A.
127
Meyers, Adam
128
Mezey, Eva
97
Miceli, Jeffrey
103
Miczek, Klaus A.
94, 124
Mien, Key
145
Mikell, Charles B.
128
Milak, Matthew S.
135
Milbrandt, Jeffrey
104
Milham, Michael
117
Miller, Alexander
105
Miller, Alexander L.
152
Miller, Andrew
153
Miller, Andrew H.
109, 138
Miller, Gregory A.
130
Miller, J.
94
Miller, Rachel
148
Miller, Raymond
106
Miller, Sue
97
Miller, Tandy J.
130
Milligan, Graeme
33
Mintun, Mark
26, 139
Mintun, Mark A.
138
Mintzer, Jacobo
131, 148
Miranda, Robert
114
Mirsky, Allan F.
90
Mitchell, Paul J.
126
Mitkus, Shruti N.
127
Mitterhauser, Markus
145
Mizoguchi, Hiroyuki
90
Mletzko, Tanja
121
119
147
152
109
104
125
114
114
111, 112,
124
116, 118,
38
131
108, 131
148
111, 113,
208
Author Index
11/17/05
7:49 AM
Mletzko, Tanya
Moberg, Paul J.
Moeller, F. Gerard
Moeller, Frederick G.
Mogg, Karin
Mohs, Richard
Moinuddin, Asif
Moller, Hans-Jurgen
Molloy, Fredrick
Molnar, Chris
Mondal, Amal C.
Monk, Christopher S.
Monkul, Serap E.
Montague, Read
Monteggia, Lisa
Monteggia, Lisa M.
Monti, Peter
Montrose, Debra M.
Moore, Gregory J.
Moore, Shonagh K. O’Leary
Moran-Gates, Taylor
Morgan, C.J.
Morozova, Elena
Morrato, Elaine H.
Morris, John
Morris, John C.
Morris, Sarah
Morris, Sarah E.
Morrison, John H.
Morrow, A. Leslie
Mosconi, Matthew
Moscrip, Tammy D.
Moses-Kolko, Eydie L.
Mossaheb, Nilufar
Mouri, Akihiro
Mu, Qiwen
Mueller, Bryon A.
Muglia, Louis
Mukherjee, Jogesh
Mukhopadhyay, Nitai D.
Mulert, Christoph
Mulia, Pierandrea
Muller, Walter E.
Mungas, Dan
Munn, Jaclyn L.
Page 209
153
151
111
144
96
128, 131
139
109
149
104, 131
125
96
140
52
91, 115
121
114
117
123
118
151
106
153
145
44
138
112
131
90
113
116
123
138
145
90
104
113
104
155
103
109
109
124
89
93
Murphy, Anne
Murphy, James M.
Murphy, Kerry L.
Murre, Jaap
Murrell, Jill
Muse, Robert
Musgnung, Jeff
Musselman, Dominique L.
Mutel, Vincent
Myers, Richard M.
Naber, Dieter
Nabeshima, Toshitaka
Nader, Karim
Nagappan, Guhan
Nahas, Ziad
Naliboff, Bruce D.
Nanda, Steve A.
Napierata, Lee
Napolitano, Barbara
Narasimhan, Meera
Narayana, Ponnada A.
Narendran, Raj
Narvaez, Jenille M.
Nash, Laurie
Nasrallah, Henry
Nasrallah, Henry A.
Nathan, Pradeep J.
Nayak, Sahana
Neale, Ann
Neary, Alaina C.
Nedza, F. M.
Negus, S. S.
113
Nelson, David
Nelson, Erika
Nemeroff, C. B.
Nemeroff, Charles
124, 153
Nemeroff, Charles B.
121, 138
Nettler, Steven
Neuhold, Lisa
Neumaier, John
Neumaier, John F.
Neumeister, Alexander
209
85
135
118
59
116
40
145
121
54
145
104, 126
51, 90
96
98
104, 131
138
121
91, 97
148, 151
124
111
129
151
134
131
131
137, 138
100
70
149
148
91, 112,
70
115
122
29, 46, 67,
92, 114,
100
137
70
114
125
Author Index
11/17/05
7:49 AM
Neve, Rachael L.
New, Antonia S.
New, AS
Newman, Amy H.
Newman, Michael E.
Newman, Stephen
Newman, Timothy K.
Newmark, Randall E.
Neylan, Thomas
Neylan, Thomas C.
Ng, Johnny
Nguyen, Chau H.
Niaura, Raymond
Nichols, Charles
Nichols, David
Nicoletti, Mark A.
Nicolini, Humberto
Niebler, Gwendolyn E.
Nierenberg, AA
Nierenberg, Andrew
Nierenberg, Jay
Nikulina, Ella M.
Nimgaonkar, Vishwajit L.
Ninan, P. T.
Ninan, Philip T.
Nnadi, Charles
Noda, Yukihiro
Nofzinger, Eric A.
Noll, Douglas C.
Noonan, Carolyn
Nordstrom, Anna-Lena
Nordstrom, Peter
Nuechterlein, Keith
Nugent, Allison C.
Nurnberger, John
Nurnberger, John I.
Nutche, Jeffrey
Nutche, Jeffrey J.
Nutt, David
Nutt, David J.
O’Brien, Charles
136
O’Brien, Charles P.
O’Connor, Megan M.
O’Dell, Laura E.
Page 210
91, 136
138
118
91, 134
125
122
95, 109
138
125
147
140
154
71
132
104
140
105
109
110
122
132, 134
124
147
122
122
132
90
147
140
143
125
125
105
96, 118
124
116, 134
147
117, 128
48
126
38, 57, 71,
112
139
134
210
O’Donnell, James M.
O’Donnell, Kelley C.
O’Donnell, Patricio
O’Donovan, Michael
O’Hara, Ruth
O’Neill, Barry
Ogden, R. Todd
Ohl, Frauke
Ohrmann, Patricia
Olfson, Mark
Olin, Jason
Olincy, A.
Olincy, Ann
147
Oliveto, Alison
Olsen, C. K.
Olson, David P.
Olson, Valerie
Ongur, Dost
Oquendo, Maria A.
135, 139, 145
Oren, Dan
Orr, Scott P.
Osincup, Dan
Oster, Scott M.
Oswald, Lynn
Otte, Christian
Ouellet, Danielle
Owen, Michael
Owens, Michael J.
Owens, W. A.
Ozdemir, Vural
Pace, Thaddeus
Pagnoni, Giuseppe
Pai, Lee-Yuh
Palamarchouk, Vitaly S.
Palmer, Abraham
Palmer, Abraham A.
Palmer, Barton W.
Palomo, Tomas
Panagides, John
Panchalingam, K.
Pandey, Ghanshyam
Pandey, Ghanshyam N.
Pandina, Gahan
125, 146
121
68, 81
132
89
138
121
109
98
96
91
102
105, 132,
112
150
132
31
120
121, 125,
130
96
111
135
146
125
106
132
114
93, 107
148
153
138
97
111
24
134
106
100
100
140
98
125, 154
106
Author Index
11/17/05
7:49 AM
Pandina, Gahan J.
Pangalos, Menelas
Pangalos, Menelas N.
148
Panza, Katie
Papakostas, George I.
Pariante, Carmine M.
Parker-Zavod, Erika
Parnas, M. L.
Parsey, Ramin V.
139
Parylak, Sarah
Pascual, Ana
Pascual, JC
Patel, Jayendra K.
Patel, Nick C.
Patel, Raman
Paterson, Neil E.
Patkar, Ashwin A.
Patterson, Paul
Paul, Steven
Paulus, Martin P.
Pava, Joel
Pavuluri, Mani
Pavuluri, Mani N.
Payne, Victoria
Paz, Rodrigo
Pearson, Jane
Pedersen, Ron
Peindl, Kathleen
Peloian, John H.
Penengo, MM
Penetar, David
Peoples, Laura
Perahia, David G.
Peralta, Jaun Manuel
Perera, Tarique
Perera, Tarique D.
Perez, Victor S.
Perich, J.
Perkins, Diana
Perrone-Bizzozero, Nora
Perrotti, Linda
Persky, Michael
Peschardt, Karina
Page 211
109, 124
24
90, 126,
Peters, Jeffrey L.
Petersen, Timothy J.
Peterson, Bradley S.
Peterson, Michael J.
Pettegrew, Jay W.
Pezawas, Lukas
141
Pfefferbaum, Adolf
Phan, K. L.
Phan, K. Luan
Phan, Kin L.
Phillips, Ann
Phillips, Katharine A.
Phillips, Mary L.
Phillips, Tamara J.
Picchini, Alyssa M.
Pickar, David
Pierre, Joseph M.
Piesla, Michael
Pihl, Robert O.
Pikalov, Andrei
152
Pilar, Lim
Pillay, Srinivasan
Pilowsky, Daniel J.
Pinard, Gilbert
Pindborg, Lars
Pine, Daniel
Pine, Daniel S.
142
Pinho, Maria
Piot-Grosjean, Odile
Pitman, Roger
Pitman, Roger K.
Pitts, Cornelius D.
Piven, Joseph
Pizzagalli, Diego
Platt, Donna M.
Plaza, P.
Plotsky, Paul M.
Polcari, Ann
Polesskaya, Oxana O.
Poling, James
Pollack, Mark H.
Pollock, Bruce
155
126
109
122
134
121, 135,
112
100
141
105
126
148
135
123
36
39
139, 140
93
125
139
97
102
49
122
123
132
141
117
57
95
105
25
126
141
141
127, 130
102
115
126
99
211
147
93
155
132
140
120, 127,
90
138
117, 137
108
115
141
141
134
121
126
132
148
113
131, 143,
130
47
99
95, 116
119
45, 99
96, 117,
107
101
117
96, 143
144
116, 119
35
142
141
109
141
150
112
118
90
Author Index
11/17/05
7:49 AM
Page 212
Pollock, Jonathan
65
Polzer, John P.
95
Pong, Kevin
109
Poole, Sabrina
137
Pope, Harrison G.
107
Popoli, Maurizio
69
Porcu, Patrizia
113
Porjesz, B.
134
Porter, Richard
54
Posey, David J.
115
Potenza, Marc N.
142
Potkin, Steven G.
100, 154,
155
Potter, William
39
Poulin, Julie
147
Prakash, A.
110
Prasad, Harish C.
115
Prasad, Konasale M.
147
Pratap, Mali
139
Pratt, Jeremy
101
Prescot, Andrew P.
120
Price, David A.
107
Price, Julie C.
116, 118,
124, 138, 139
Price, Lawrence
145
Price, Lawrence H.
114
Price, R. Arlen
103
Prieto, David
100
Pritchett, Yili L.
107
Prudic, Joan
96
Puigdemont, D.
141
Pulicicchio, Claudine
126
Pultz, Joseph
131, 143,
152
Purselle, David
121
Pustavoitau, Aliaksei
118
Qaadir, Asfia
134
Qiang, Mei
136
Quesenberry, Charles P. 101
Quirk, Gregory
84
Quiroz, Jorge A.
123
Radant, Allen D.
105
Radel, Jeffery D.
122
Radulovic, Jelena
154
Ragland, John D.
147
Raison, Charles L.
Rajarethinam, RP
Rama, Arjune K.
Ramamoorthy, Siva
Ramsey, Dave
Rao, Jagadeesh S.
Rao, Uma
Rapoport, Judith
105
Rapoport, Stanley I.
Rasenick, Mark
Rasenick, Mark M.
Rasgon, Natalie
Rasgon, Natalie L.
Raskind, Murray
Rasmussen, Hans
Rasmussen, Kurt
Rauch, Scott
Rauch, Scott L.
Raventos, Henriette
Rawlings, Robert
Rech, Richard
Redish, A. David
Redwine, Jeffrey M.
Reed, Bruce
Reeves, Scott T.
Reich, W.
Reinhart, Peter H.
Reisberg, Barry
Reiss, Allan
Reist, Chris
Reite, Martin
Reite, Martin L.
Ren, Xinguo
Ren, Zhaoxia
Ren-Patterson, R.
Ren-Patterson, Renee
Renshaw, Perry F.
134
Revicki, D.
Reyes, Eduardo
Reyes, Magali
Reyes, Niko
Reynolds, Charles F.
Reynolds, Margaret F.
212
109
147
101
126, 148
131
154
142
37, 81,
139, 154
50, 69
98
95
142
79
119
147
47, 84
118
105
136
124
52
90
89
106
134
90
90
97
148
148
139
98, 125
137
151
149
120, 132,
131
147
109
123
124
142
Author Index
11/17/05
7:49 AM
Ribeiro, Saulo
Rice, John
Rice, Kenner C.
Rich, Brendan A.
142
Richards, Michele R.
Richards, Misty
Richardson, Heather
Richelson, Elliott
Richtand, Neil M.
Richter, Margaret A.
Ridder, Stephanie
Risbrough, Victoria
Risbrough, Victoria B.
Rivier, Catherine L.
Rizavi, Hooriyah S.
Robbins, Trevor
Roberson-Nay, Roxann
Robert, Forman
Robert, Mach H.
Robert, Zucker A.
Roberts, Angela
Roberts, James L.
Robertson, A. S.
Robertson-Plouch, Carol
Robichaud, Al
Robinson, Benjamin M.
Robinson, Delbert G.
151
Robinson, Donald S.
Robinson, Jim
Robinson, Michael J.
Robinson, Terry
Rodd, Zachary A.
Rodolico, John
Rodriguez, Stephen
Rodriguez, Steve
Rodriguez, Steven
Roehrs, Timothy
Rogacki, Nancy
Rogers, Laura S.
Rohrer, Susan P.
Rohsenow, Damaris
Rojas, Don
Rojas, Donald C.
Page 213
146
124
113
96, 117,
Role, Lorna
Rollema, H.
Rollis, Denise
Rosa-Neto, Pedro
Roseboom, Patrick H.
Rosen, Amy S.
Rosenbaum, Jerrold
Rosenblum, Leonard A.
Rosenheck, Robert
Rosenkranz, Amiel
Rosenstein, Donald
Rosenthal, Norman R.
143
Rosenzweig-Lipson, S.
Rosillon, Dominique
Rosso, Isabelle
Roth, Bryan
Roth, Thomas
Rothman, Richard B.
Rotrosen, John
Rowlett, James K.
Roy, Alec
Roy-Byrne, Peter P.
Rubens, Robert
Rubinow, David
Rujescu, Dan
Ruparel, Kosha
Rupp, Claudia I.
Ruppert, Andreas
Russo, Christie
Ryan, C. E.
Ryder, Sean
Rypma, Bart
Saad, Ziad S.
Saavedra, Juan M.
Sacco, Kristi A.
Sacheim, Harold
Sacher, Julia
Sachs, Gary
Sackeim, Alexander
Sackeim, Harold A.
Sahakian, Barbara
Saikali, Khalil
Saint Marie, Richard L.
Salzman, Carl
97
139
134
67
135
95
120
64
142
134
125
42, 72
117
137
138
119
45
107
148
122, 151
109
131
129, 148,
142
92
107
80, 93
135
117
104, 107
105
106
136
101
113
97
114
148
139
213
65
148
96
95
121, 142
95
143
114
55, 62
148
49, 79
107, 108,
126, 148
104
132
50, 153
97, 109
97
92, 134
142
92
143
97
49
109
128
151
109
90
122
131
140
120
143
105
126
145
122, 143
126
96
35
94
149
28
Author Index
11/17/05
7:49 AM
Sambataro, Fabio
138
Sambunaris, A.
Samuelsson, Mats
Sananbenesi, Farahnaz
Sanchez, Yadira
Sanders-Bush, Elaine
Sangoi, Raj
Sano, Mary
Sanz, Javier
Sassi, Roberto B.
Saxena, Kirti
Saxena, Sanjaya
Saxon, Andrew J.
Scahill, Lawrence
Schaefer, Catherine A.
Schaefer, Desiree M.
Schanberg, Saul M.
Schapiro, Mark B.
Schatzberg, Alan
Schatzberg, Alan F.
Schechter, Lee
Schechter, Lee E.
Scheftner, Bill
Scheiffele, Peter
Scherrer, Jeffrey F.
Schiltz, Craig A.
Schlaepfer, Thomas E.
Schloesser, Robert J.
Schmahl, Christian
Schmajuk, Mariana
Schmid, Wolfgang
Schmidt, Mark
Schmithorst, Vince
Schneider, Lon
Schoepp, Darryle D.
Schooler, Nina
Schooler, Nina R.
Schork, Nicholas J.
Schreffler, Erica R.
Schrick, Christina
Schulkin, Jay
Schultz, Robert T.
Schulz, Charles
Schulz, S. C.
Page 214
90, 116,
Schutz, Gunther
Schwandt, Melanie
Schwandt, Melanie L.
Schwartz, Kelly
Schwarzmann, Lesley K.
See, Ronald E.
Segal, David S.
Segman, Ronen
Segman, Ronnen H.
Sei, Y.
Sei, Yoshitatsu
Seillier, Alexander
Seitz, Patricia K.
Self, David W.
Semenova, Svetlana
Sen, Srijan
Seraji-Bozorgzad, Navid
Sethuraman, Gopalan
Sevak, Rajkumar
Sevy, Serge
151
Shah, Kamini R.
Shaham, Yavin
Shahid, Mohammed
152
Shalev, Arieh Y.
Shalom, Galit
Shampine, Lawrence J.
Sharma, Rajiv P.
Shaw, Philip
Shear, Paula K.
Sheehan, David V.
Sheikh, Javaid
Sheikh, Nabila
Shekhar, Anantha
Sheline, Yvette
Sheline, Yvette I.
Shelton, Richard C.
Shen, Joan
Shen, Pei-Hong
Shen, Shuyi
Sher, Leo
Shiffman, Saul
Shilling, Paul
Shilling, Paul D.
110
125
154
130
132
103
89
100
140
97
143
112
66
101
144
109
139
46
106, 122
126
109
124
65
142
135
143
121
119
96
120
39
94
62
108
148
148
105
91
154
115, 118
140
151
152
214
120
115
92, 135
107
143
94, 135
149
125, 143
149
151
149
107
111
91
135
96
118
126
93
129, 148,
142
80
108, 151,
143
125
89
105
37, 115
99
99
89
149
149
139
138
119, 143
151
137
107
135
71
104
149
Author Index
11/17/05
7:49 AM
Shim, Seong
Shoaf, Susan
Shoemaker, Jody M.
Sholar, Michelle B.
Shorman, Igor
Shrivastava, Ram K.
Shrivastava, S. P.
Shungu, Dikoma C.
Sibille, Etienne
Sibley, David R.
Sibon, Igor
Sicard, Tricia
Siegel, Arthur J.
Siegel, Steve
Siegel, Steven J.
Siegle, Greg
Siegler, Ilene
Siegler, Ilene C.
Siever, Larry
58
Siever, Larry J.
Siever, LJ
Silbersweig, David
Sills, Terry
Silveri, Marisa
Silverman, Jeremy
Simmons, Julian
Simmons, Rosa M.
Simmons, Tracy
Simpson, George
Simpson, Norman
Singh, Jaskaran
Sinha, Rajita
Sircar, Ratna
Siris, Sam
Sitzer, David I.
Siu, Cynthia
Skudlarski, Pawel
Skupny, Alicja
Slawecki, Craig J.
Sliwerska, Elzbieta
Smagin, Gennady N.
Small, Gary
Small, Joyce
Smith, A. R.
Page 215
144
92
149
111, 114
114
144
144
128, 137
90
154
116
95
111, 114
126
149
141
133, 146
109
24, 25, 42,
138
118
47
99
132
114
138
107
93
105
121
146
71
135
104
151
129, 154
104
111
136
119
111
34
131
106
215
Smith, Ashley K.
Smith, Eric L.
Smith, Gwenn
Smith, J. K.
Smith, Kelli E.
Smith, Lisa J.
Smith, Robert C.
Snaterse, Mark
Snow, Diane
Snyder, Avi
Snyder, Doug
Soares, Jair
Sofuoglu, Mehmet
Sokolov, Boris P.
Solomon, D. A.
Sookman, Debbie
Soorya, Latha
Sorensen, Jill
Soto-Perello, Jose
Spanagel, Rainer
Specker, Sheila M.
Spencer, Thomas
Spencer, Thomas J.
Spiegel, David
Spielman, Daniel
Spindelegger, Christoph
Spinelli, Simona
Sporn, Alexandra
Sprock, Joyce
Srivastava, Lalit
Stack, Gary
Stahl, Stephen M.
Stanford, Arielle D.
Stanford, Kevin
Stanford, Kevin E.
Stanga, Zeno
Stanley, Barbara H.
Stanley, Jeffrey A.
Stead, John D.
Steadman, Timothy
Steffens, David C.
Stein, Joel
Stein, Murray B.
Steinberg, Joel L.
Stenzel-Poore, Mary
130
114, 137
90
114
96
106
149
150
123
139
38
140
112
150
122
95, 116
115
39
148
76
113
78
134
91
97
145
115
105
101, 129
41
126, 148
144
150
135
94, 126
143
125
140
97
149
89
153
139, 140
111, 144
142
Author Index
11/17/05
7:49 AM
Stephan, Dietrich
Stepien, I.
Stern, Jessica
Stevens, Rachel
Stewart, Daniel G.
Stigler, Kimberly A.
Stolinski, Lisa R.
Stone, William S.
Stout, Robert L.
Strakowski, Stephen
Strakowski, Stephen M.
117, 126, 144
Straub, Richard
152
Straub, Richard E.
150
Stringer, Elizabeth
Strode, Nicole L. Baganz
Sturm, Volker
Su, Jing
Subhash, Aryal
Sukhodolsky, Denis
Sullivan, Edith V.
Sullivan, Susan K.
Sumner, Jennifer
Sunderajan, Prabha
Sunderland, Trey
44
Suomi, Stephen J.
109, 113, 115, 135
Suppes, Trisha
Sureddi, Suresh
Suresh, Rathi
Surguladze, Simon
Surwit, Richard S.
Suslow, Thomas
Susser, Ezra S.
Sust, Steven
140, 152
Sutcliffe, James S.
Sutherland, Ashley N.
Sutton, Virginia K.
Suyenobu, Brandall
Suzuki, Kastuji
Svarer, Claus
Page 216
86
154
89
101
140
115
146
105
141
56
94, 99,
25, 141,
127, 141,
119
93
143
90
139
155
90
142
115
121
26, 27, 34,
92, 95,
123
123
134
141
109
98
101
102, 116,
115
150
126
138
98
119
216
Svensson, Torgny
Svensson, Torgny H.
Swain, James E.
Swann, Alan C.
Swanson, Chad J.
Swanson, James M.
Swedish, Kristin
Sweeney, John A.
Sweet, Lawrence H.
Swerdlow, Neal
Swerdlow, Neal R.
150
Swift, Robert
Swift, Robert M.
Swyzen, Wim
Szabo, Sandor
Szalayova, Ildiko
Szeszko, Philip R.
Szulc, Kamila
Szumlinski, Karen
Szumlinski, Karen K.
Tai, T.C.
Talan, Jamie
Talavage, Thomas
Talbot, Peter S.
Talbot, PS
Talkowski, Michael E.
Talledo, Jo A.
Talmage, David
Tambini, Arielle
Tamminga, Carol
Tamminga, Carol A.
Tamura, Roy N.
Tan, Hao Y.
Tan, Hao Yang
Tan, Hao-Yang
Tan, Yun L.
Tancer, Manuel E.
Tang, Cheuk
Tang, Min
Tang, Yilang
Tarazi, Frank
Tarazi, Frank I.
Tariot, Pierre
Tauscher, Johannes
150
130
140
111, 144
96, 144
111
89
139
136
101
105, 149,
61, 114
112, 136
130
148
97
102, 151
103
24
151
108
40
116
129
118
147
150
63
102
29, 142
129, 150
108
140
152
102
153
136
140
99
92
92
151
62, 91
145
Author Index
11/17/05
7:49 AM
Taylor, Benjamin
Taylor, Cindy
Taylor, Joy
Taylor, Kristin
Taylor, Robert E.
Taylor, Stephan
Taylor, Stephan F.
Teale, Peter
Teicher, Martin H.
Telang, Frank
Terrace, Herbert S.
Terranova, Jean-Paul
Thakkar, Vatsal
Thase, Michael E.
122, 141, 145
Thiele, Todd
Thomas, A.
Thomas, Binu
Thomas, Mary L.
Thomas, Steven
Thomas, Suzanne
Thomas, Yonette
Thompson, Paul M.
Thomsen, Morgane
Ticku, Maharaj K.
Tidey, Jennifer
Tiefenbacher, Stefan
Tillemans, Monique P.
Tin, Adrienne
Tinklenberg, Jared R.
Tirado, Carlos F.
Toalston, Jamie E.
Todorov, C.
Todtenkopf, Mark S.
Tohen, Mauricio
151
Tokarczyk, Jan
Tollefson, Gary
Tollefson, GD
Tomasi, Dardo
Tomita, Hiro
Tomoda, Akemi
Tone, Andrea
Tononi, Giulio
Tornatzky, Walter
Page 217
135
126
89
115
136
140
118, 137
139, 148
141
111
123
121
143
98, 99,
Torossian, Carol
Trapp, Bruce D.
Treiber, Kristina
Tremblay, Jacques
Tremblay, Philippe
Trisdorfer, Roanna
Trivedi, Madhukar H.
145
Trotman, Louis
Truesdale, Matthew
Tsai, Guochuan E.
Tse, Maric T.
Tsopelas, Nicholas
Tsou, Pon
Tsuang, Debby W.
Tsuang, Ming T.
Tucker, Vivan L.
Tummala, Raj
Tunbridge, Elizabeth
Tunbridge, Elizabeth M.
Turetsky, Bruce I.
Turkoz, Ibo
Turkoz, Ibrahim
124
Twamley, Elizabeth W.
Tyrka, Audrey R.
Uhart, Magdalena
Uhde, Thomas W.
Ujike, Hiroshi
Ungerleider, Leslie
Upadhyaya, Ameet
Upadhyaya, Himanshu
Upadhyaya, Margi
Urani, Alexandre
Vaidhyanathaswamy, S.
Vakkalanka, Radha K.
Vakkalanka, R.
Valdes, Ignacio
Valdez, Jeffrey N.
Valente, Elizabeth
Valuck, Robert J.
Van Ameringen, Mickael
Van Den Buuse, M.
Van der Veen, Jan W.
Van Heertum, Ronald L.
53
94
150
111
78
93
92
140
92
136
114
142
150
125
89
136
135
95
97, 136
99, 122,
126
91
110
111
145
141
28
132
92
217
90
23
124
96
95
138
121, 122,
123
123
147
126
139
147
147
107
126
123, 145
25, 151
149
151
106
95, 105,
151
114, 145
146
123
51
45
147
93
147
120
149
150
127
111
147
141
145
122
51
137
121
Author Index
11/17/05
7:49 AM
Van Kammen, Daniel P.
Vance, Jeffery
Vapnik, Tanya
Vargas, Gabriel
Vasquez, Delia
Vaughan, Roxanne
Vawter, Marquis P.
Vecsey, Chris
Veenstra-Vander Weele, J.
Velligan, Dawn
Velligan, Dawn I.
Vera, Elizabeth
Verbitskaya, Elena V.
Verbitsky, Miguel
Verchinski, Beth A.
141
Verdeli, Helena
Vermetten, Eric
Versavel, Mark
Vesta, Yethiraja
Videbaek, Charlotte
Vieta, Eduard
Villafuerte, Sandra M.
Vincow, Evelyn
Vinogradov, Sophia
Vinton, Deborah T.
Viviano, Tom
Voet, Hubertus H.
Voglmaier, Susan
Vogt, Jerry
Volkow, Nora D.
Vollenweider, Franz
Von Zastrow, Mark
151
Vosburg, Suzanne K.
Votaw, John R.
Voytek, Bradley
Vythilingam, Meena
Wadenberg, Marie-Louise
Wadsak, Wolfgang
Wager, Tor D.
Wagner, Angela
Wagner, Christopher
Wagner, Karen
Wagner, Tara
Page 218
147
146
96
151
97
134
145
153
134
100
152
144
112
134
116, 127,
Walker, Glenn B.
152
Walker, John
131
Walker, Mary M.
96, 144
Walker, Quentin D.
112
Walkup, John
66
Walline, Crystal C.
91
Walsh, B. T.
107
Walsh, David M.
145
Walsh, James K.
109
Walton, Kimberly
136
Wand, Gary
146
Wang, Dayong
90
Wang, Gene-Jack
141
Wang, Jun-Sheng
103
Wang, Liqun
120
Wang, Mei
152
Wang, Wei V.
151
Wang, Yang
116
Wang, Yun
98
Ward, Herbert E.
95
Warner, Virginia
99
Warren, Kenneth
137
Warren, Stephen
83
Warrington, Lewis
129
Wasserman, Stacey
115
Wassink, Thomas H.
116, 127
Watkin, JG
110
Watkins, Lana
97
Watner, Dryden
114
Watson, Adam
132
Watson, Stanley
97
Watson, Stanley J.
93, 145
Watts, Val J.
154
Waugh, Christian E.
140
Webster, Maree J.
101
Wedig, Michelle M.
118
Weickert, Cynthia
63
Weickert, C. S.
101, 102
Weilburg, Jeffrey B.
152
Weiler, Martin A.
129
Weinberger, Daniel
29, 30, 40,
42, 63, 152
Weinberger, Daniel R.
40, 90,
102, 116, 120, 127, 137, 138, 140,
141, 149, 150, 151, 152
99
119, 145
103
114
119
48
145
141
152
117, 142
149
149
154
153
111
72
33, 69,
112
112
95
99
150
145
140
116
97
122
128
218
Author Index
11/17/05
7:49 AM
Weiner, Michael
Weinshenker, David
Weinstein, Mitchell
Weiss, Anthony P.
Weiss, Friedbert
Weiss, Susan
Weissfeld, Lisa A.
Weissman, Myrna M.
Welch, Ron
Wells, Barbara
Welsh, Robert C.
Wernicke, Joachim F.
Wesnes, Keith A.
Wess, Juergen
Wessel, Thomas
West, Britt
Westenberg, Herman
Westenberg, Herman G.
Wetterberg, Lennart
White, Tara L.
White, Tonya
Whitfield, Susan L.
Whitsel, Rachel
Whybrow, Peter C.
Wickramaratne, Priya
Wiegand, R.
Wiegand, Ryan E.
Wier, Lauren
Wilhelmsen, Kirk C.
Wilkins, Consuelo
Williams, Mark J.
Williams, Michael
Williams, Redford
Williams, Redford B.
Williams, Wendol A.
Williamson, Douglas
Winsky, Lois
Wint, Dylan
Wirshing, Donna A.
Wirshing, William C.
Wisner, Katherine L.
Wisniewski, Stephen
Wisniewski, Steven
Wittchen, Hans-Ulrich
Woerner, Margaret
Page 219
89
31
106
152
57, 71
80
139
99, 137
150
111
118
98, 107
109
92
97
131, 152
119
145
104
136
152
104
144
95
99
134
115
114
93
139
91
109
133, 146
109
136
99
36
152
132
132
138
122
122
95
148
Woerner, Margaret G.
Woertwein, Gitta
Wohlreich, MM
Woldbye, David P.
Wolf, Dan
Wolf, Fred
Wolinsky, Toni D.
Wong, Dean
Wong, Dean F.
Wong, Dona Lee
Wong, Erik
Wong, Erik HF
Wong-Faull, David C.
Wood, Marcelo A.
Wood, Ruth
Wood, Suzanne E.
Woodgett, Jim
Woods, Scott W.
Woody, George E.
Woolston, Dixie J.
Woolwine, Bobbi J.
Wozniak, David
Wozniak, Janet
Wozniak, Jeffrey R.
Wright, Christopher I.
Wright, Ron
Wu, Chi-Cheng
Wu, Jingwei
Wu, Min
Wu, Nan-Ping
Wu, T. John
Wu, Xiaoling
Xian, Hong
Xiang, Jim
Xu, Haiyun
Xu, Ke
Xu, Wen
Xu, Zhi-Qing D.
Yale, Scott
Yamada, Kiyofumi
Yamamoto, Tsuneyuki
Yan, Bing
Yang, Ruoyong
Yang, Xiaoju
Yang, Yili
219
129
92
110
92
147
103
96
66
39, 119
108
152
151
108
153
43
118
60
130
112, 137
144
109
104
122
113
118
107
90
116
153
108
89
130
142
143
129
129, 137
122, 151
144
128
51
137
122
148
146
147
Author Index
11/17/05
7:49 AM
Yap, Jasmine J.
Yaw, Senyah
Yehuda, Rachel
143
Yesavage, Jerome A.
Young, Elizabeth A.
146
Young, Larry
Young, Simon N.
Youngstrom, Eric A.
Yu, Yang
Yuan, Qiaoping
Yurgelun-Todd, Deborah
Yurgelun-Todd, D. A.
Zacher, Christiane
Zacny, James
Zajac-Benitez, Caroline
Zaleska, Margaret
Zandi, Peter
Zappert, Laurel N.
Zarate, Carlos
Zarate, Carlos A.
Zavadoski, W. J.
Zboyan, Holly
Zelazny, Jamie
Zhang, Hanting
Zhang, Jean
Zhang, Lei
Zhang, Wei
Zhang, Xiang Y.
Zhang, Xuexiang
Zhang, Ying
Zhao, Y.
Zhao, Zaorui
Zheng, Kang
Zheng, Ling
Zhong, Huailing
Zhou, Dong F.
Zhou, Xianjin
Zhou, Yuan
Zhu, Baojin
Zhu, Haojie
Zhu, Wei
Zhu, Young
Zielinski, Tanya
Page 220
124
101
74, 125,
Zink, Mathias
Ziolko, Scott K.
Zisook, Sidney
Ziwich, Rachel
Zoltick, Brad
Zorn, Stevin
Zou, Mu-Fa
Zubenko, George
Zubieta, Jon-Kar
Zuchner, Stephan
Zvartau, Edwin E.
89
106, 145,
83
113
146
128
137
95
132, 137
120
85
123
109
124
142
27
146
148
123
125
146
126
111, 146
97
153
144
99
131
125
144
89
144
153
116
90
100, 103
103
90
98, 101
91
220
120
124, 139
79
102
140
152
134
34, 44
85, 119
133, 146
112
MAPS 2006.qxp
11/17/05
7:50 AM
Page 221
MAP
69' x 36'
Kohala 1
BOARDROOM
Lagoon
Lagoon
Lanai
35' x 55'
28' x 36'
Kona 2 Kona 3
21' x 36'
222
Waikoloa Suites
Waikoloa 1 Waikoloa 2 Waikoloa 3
31' x 23' 31' x 23' 31' x 23'
30' x 36'
Kona 1
80' x 36'
Kona 4
80' x 36'
Kona 5
Kona Ballroom
Grand
Staircase
up
To
Main Lobby
7:50 AM
LOUNGE
Queen's 4
35' x 55'
36' x 55'
King's 1
Queen's 5
37' x 55'
Queen's 6
36' x 55'
Grand Promenade
95' x 134'
King's 2
37' x 55'
Monarchy
Function and Meeting Space
11/17/05
69' x 36'
Kohala 2
69' x 36'
Water’s Edge Ballroom
King's 3
120' x 206'
69' x 36'
Kohala 3
Grand Ballroom
HILTON WAIKOLOA VILLAGE
Kohala 4
Kohala Ballroom
MAPS 2006.qxp
Page 222
MAPS 2006.qxp
11/17/05
7:50 AM
Page 223
223
MAPS 2006.qxp
11/17/05
7:50 AM
Page 224
Future ACNP Annual Meetings
Dates
Hotel
Location
December 3 - 7, 2006
December 9 - 13, 2007
December 7 - 11, 2008
The Westin Diplomat
Boca Raton Resort & Club
The Fairmont Scottsdale Princess
Hollywood, Florida
Boca Raton, Florida
Scottsdale, Arizona
Summary Program
Event
Time
Location
On-Site Registration
Pre-Paid Registration
10:00 am - 6:00 pm
10:00 am - 6:00 pm
Kona 3
Outside Waikoloa 1
Teaching Day
Hot Topics
7:00 am 7:00 am 8:00 am 2:30 pm 7:00 pm -
5:00 pm
5:00 pm
12:30 pm
5:00 pm
8:00 pm
Kona 3
Outside Waikoloa 1
Monarchy Ballroom
Kona 4 & Kona 5
Kona 4
Awards Presentation
President’s Plenary
Poster Viewing
Panel Sessions
Poster Session I
Issue Oriented Study Groups
7:00 am 7:00 am 8:00 am 8:30 am 10:30 am 1:00 pm 2:30 pm 5:30 pm 7:45 pm -
5:00 pm
5:00 pm
8:30 am
11:30 am
4:30 pm
2:15 pm
5:00 pm
7:30 pm
9:00 pm
Kona 3
Outside Waikoloa 1
Monarchy Ballroom
Monarchy Ballroom
Kohala Ballroom
Monarchy Ballroom
See Program Book
Kohala Ballroom
See Program Book
Panel Sessions
Poster Viewing
Issues in Ethics
Panel Sessions
Poster Session II
7:30 am - 5:00 pm
7:30 am - 5:00 pm
8:00 am - 10:30 am
10:30 am - 4:30 pm
12:00 pm - 2:30 pm
2:30 pm - 5:00 pm
5:30 pm - 7:30 pm
Kona 3
Outside Waikoloa 1
See Program Book
Kohala Ballroom
Monarchy Ballroom
See Program Book
Kohala Ballroom
Town Hall: Clinical Trials Registry
Registration
Panel Sessions
Poster Viewing
Business Meeting (Members Only)
Memorial Symposium
Panel Sessions
Poster Session III
7:00 am 7:30 am 8:00 am 10:30 am 10:45 am 1:00 pm 2:30 pm 5:30 pm -
Kona 4
Kona 3
See Program Book
Kohala Ballroom
Kona 4
Queen’s 6
See Program Book
Kohala Ballroom
Registration
Panel Sessions
Panel Sessions
Reception
7:30 am - 3:00 pm
8:00 am - 10:30 am
12:30 pm - 2:00 pm
2:30 pm - 5:00 pm
7:30 pm - 10:30 pm
Kona 3
See Program Book
Kona 5
See Program Book
Monarchy Ballroom
ACNP Service Center
Saturday (registration only)
Sunday-Monday
Tuesday-Wednesday
Thursday
10:00 am 7:00 am 7:30 am 7:30 am -
6:00 pm
5:00 pm
5:00 pm
5:30 pm
Kona 3
Kona 3
Kona 3
Kona 3
ACNP Computer Center
Sunday-Wednesday
Thursday
7:30 am - 9:00 pm
7:30 am - 5:00 pm
Kona 2
Kona 2
8:00 am
5:00 pm
10:30 am
4:30 pm
11:45 am
2:15 pm
5:00 pm
7:30 pm
ACNP Executive Oﬃce • 545 Mainstream Drive, Suite 110 • Nashville, TN 37228

Program Book

Transcription

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