Immortality: myth or becoming reality?

Syntropy 2013 (3): 168-207
ISSN 1825-7968
Immortality: myth or becoming reality?
On the conservation of information
Dirk K.F. Meijer1
Abstract
Immortality, in the personal sense, is defined as the potential to freely choose the moment of
individual death, rather than having the meaning of eternal life. Man is a symbol and metaphorcreating being who apprehends the world through his imaginary power. The desire to give a place to
an “inevitable“ individual death, has led mankind to many powerful immortality symbols, of which
some of the most important ones will be discussed. Apart from individual immortality, the term is
also used in relation to collective survival of mankind as well as an ultimate rebirth of our universe.
Cell biology shows that humans are programmed to die and daily experience shows that we cannot
escape fatal wear of our body. But should we really be satisfied with our mortal organism or should
we declare war on this ancient enemy, and rather decide that death is not invincible? Genetic and
nano-technological interventions in our body will become possible, but obviously will raise many
ethical questions. How will the future on our precious planet evolve with regard to individual life
span and the quality of life of its inhabitants? And how dominant will biomedical technology
become in further pushing the limits of longevity? Molecular and genetic aspects of current
longevity research shed a spectacular light on the first attempts to master immortality.
We entered the era of digital immortality while broadly experienced transcendental awareness
suggests mental survival. Some claim that dying is only virtual on the basis of quantum physics and
is being interpreted as one form of conservation of information.
Transhumanism advocates that mankind may become the first species in evolution to create its own
successors. Human/machine hybrids (cyborgs) will be designed and the universe might be finally
recreated by super-intelligent civilizations, providing a cyclic process of rebirth of our universe.
1
Em. Professor of Pharmacology and Therapeutics, University of Groningen, The Netherlands Mail:
meij6076@planet.nl
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Contents:
Introduction
1. Immortality in a historical perspective, pages:
2. Health technology: hope for a longer life?
3. Do we live on through our offspring or can we survive in cyberspace?
4. The physics of the future and its implications for immortality
5. Transcendence of the individual self
6. The significance of individual life in a fine-tuned Universe
7. The distant future: death and rebirth of the Universe
8. Final summary
9. References
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Introduction
The author defines immortality as the potential for humans or mankind to freely choose the moment
of (individual) death, rather than using the term in the sense of eternal life. Man is a symbol and
metaphor creating being who knows the world through his imaginary power. The human desire to
give a place to the seemingly inevitable death, has led to many powerful immortality symbols and
opinions (see Fig.1), of which some of the most important ones will be discussed in the following.
For example, we may distinguish between individual survival (of the self) versus collective
immortality (of humanity). In addition, we know terms such as living on in the other (through our
offspring). In addition, people may live on through their works (for instance digital immortality), or
one may put hope in developments in technological and biomedical life extension.
Fig. 1: Philosophical statements about (im)mortality
An incredible amount of thought has been written about (im)mortality. When these terms are
"Googled" one will find hundreds of thousands of hits and the amount of literature is literally
overwhelming. There are even academic dissertations written about the subject and some of them
are really excellent! (van Bergen, 2002, Vidal, 2012)
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In this essay the author will take a position of a "neutral" observer of this information and review a
number of critical issues and opinions, albeit on the basis of a personal selection. These various
aspects will be dealt with without much value judgments, so that the readers in their own way can
judge their relative importance and value. It will become clear that immortality is a multilayered
concept that deserves an integral approach. Some rightfully state that we should pursue
"immortality" only in the brief life given to us. In this way we may finally become fully aware of
the perfect intertwining of life with nature and the cosmos and become reconciled with the
temporality of our existence, in favor of those who come after us. [Cave, 2012]. Although this is a
sensible attitude, it is certainly not the whole story, as will be shown in the following.
1. Immortality in a historical perspective
The desire for immortality fascinated mankind already from the beginning of human history 2200
years BC, (see link Epic of Gilgamesh, Fig. 2). This mythological king, who sought immortality,
was convinced to find it in the form of a plant which, according to the myth, after eating it, would
provide eternal life. He plucked the particular plant from the seabed through tying heavy stones to
himself, in order to lower his body to the bottom of the sea. Back on the beach, however, he fell
asleep and after waking up discovered that it was stolen by a snake. This is probably typical for this
type of quests, thinking that you have your hands on immortality, it eludes again at the same time!
Gilgamesh seems still alive also in this time, albeit in the virtual world of computer games (see
upper right inset, Fig. 2).
Fig. 2: The Gilgamesh Epic
Pyramids in Egypt were the supposed burial tombs of the pharaohs, but subsequent interpretations
indicate that these enormous structures, with a still unexplained construction technology, in fact
were intended as "soul-moving machines". Retrospective cosmological calculations suggest that the
typical inclining channels of the burial chambers, appeared to be aimed precisely at those stellar
constellations in which the Egyptian Gods were supposed to house, calculated back to the period of
the probable construction of the particular pyramids. So Egyptians thought to acquire immortality
through thorough cosmological knowledge!
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2. Health technology: hope for life extension?
Man dies from trauma, disease or aging: all three processes are open to countermeasures (Fig. 3).
Aging arises partly due to wear, oxidation and attrition of the ever more energy costing gene repair.
The current and future developments in biomedical science offer perspectives for longer and
healthier lives, that is, if we do not allow the living conditions in our world to deteriorate further
(Best, 2012, De Grey, 2007 and the link Ageing). How old we will be able to become is certainly
influenced by our own personal experience and attitude towards the meaning of aging. It is common
knowledge that growing old is facilitated by an optimistic life style and courage to deal with the
inevitable problems of aging. Staying healthy, according to modern concepts, requires an integrated
approach, in which in each stage of the life-cycle, an optimal life style is adopted and also a right
mix of interventions, tailored to the individual, is chosen. Proper drug treatment is an example of
such an intervention where major progress was made.
Fig.3: Stop aging: we may live to 120 years…
However, medication is often considered too abundant and multiple drugs per individual are
sometimes uncritically prescribed, especially for the elderly (called poly-pharmacy). This may lead
to fatal side effects or even to downright abuse (drug addiction): advanced drug-technology has also
its downside!
Will we live to 120 and if so, should that be considered as natural or unnatural?
Long life and virtual immortality is not a new phenomenon in nature (see internet link List of long
living organisms): not only colonies of primitive protozoa and bacteria are in fact immortal but even
some animals can become more than 8.000 years old! (Fig. 4). The oldest human, recorded so far,
was a French woman, living up to 122 years. She appeared quite smart at that age: when a journalist
visited her for her birthday and after the interview said: well, see you next year perhaps, she
answered: I count on that, you do not look too bad to me! In the circles of gerontologists and
transhumanists (see link Transhumanism), it is strongly believed that life span can be boosted to an
average of 120 in the coming years, through preventive health measures. At the time that this is
achieved, genetic engineering will be developed to such a perfection that quite soon after that an
average of 250 years is within reach, including an appropriate quality of life....The famous British
gerontologist Aubrey De Grey tries to proactively deal with concerns people might have with his
focus on extreme longevity research. He covers several contra-arguments such as overpopulation,
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immortal tyrants, only the rich, first things first and playing god. And also discusses some other
often heard remarks: I don't even want to live to 1000; I'm too old to have any chance of benefiting;
we should focus on curing disease and feeding the starving first; let's become better people first –
we don't deserve long lives; we should focus on postponing frailty, not death; life is already long
enough to do the full range of what life offers; we'd be denying future generations the right to be
born; this would not be saving lives, it would be extending lives; we'd forget so much about our
youth that we wouldn't be the same person. De Grey states that this is a new perspective for those
individuals who do not simply accept a restricted life time of 70-80 years and sees it as a typical
human endeavor: modern man always pushes his limits (De Grey and Rey, 2007)! For others, this
life-sustaining tendency represents an obvious ecological disaster scenario and is also viewed upon
as contrary to the idea of evolution (survival of the fittest implies selection and the necessity of
dying). For example, would there enough space and food for all those people who would wish to
live so much longer? Yes, say the advocates of life extension: in the western world we now throw at
least 50% of our food supply away, its production can be much, much higher and the unequal and
unjust global distribution of food in fact is now the biggest problem. Moreover, they claim, we may
eventually inhabit our oceans or ultimately colonize other planets. In any case, there seem to be
only two choices: a short but powerful life or a much longer but perhaps more boring one...
However the latter is a projection on the basis of the present state: why would a longer life with
high quality in the future be boring anyway? What, on the contrary, would be won through the
preservation of knowledge and experience!
Fig. 4: Current human life is on the average rather short (70 - 90 years), but even a life span of 120 is now
possible (see miss Calment!). In this century, a 150 years life span may become feasible too and some
scientists claim that the first human that will become 150 year is already born! Some genes have been
identified that code for proteins that may promote longevity, (for example SIRT 1, DAF -16 and INS-7). Note
the variable life span of other species (right above).
Since the recent genetic / molecular biological revolution, expectations for a rapid development of
more effective and safer medicines and gene therapy, are high. The latter includes gene correction,
replacement and foreign gene transfection. More recently it has become clear that composition and
expression of our genes is not always the only factor in the etiology and / or maintenance of a
disease. Environmental factors such as over-consumption, stress, insufficient exercise, pollution,
hunger and social insecurity are often very dominant [Jablonka, 2006]. Our chronic welfare diseases
are often over-eating' diseases and there is a huge mismatch between our genes and the current
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dietary patterns. We are not so much victims of our genes as well of our collective behavior! (see
link Ben Best)
Healthy food consumption and calorie restriction
Conversely, there are indeed long lasting and favorable effects on the expression and repair of
longevity genes by the quality of food that we use (low calorie, high fiber and antioxidants in fresh
fruits and vegetables, (see Fig. 5) and a modest daily food consumption. It is certainly better to stay
relatively lean by calorie restrictions and combine that with regular exercise. Research with mice on
a low or high calorie diet regimes showed that the "fasted" animals lived at least three times longer
compared with mice who received excess of food every day!. Calorie restriction is both for the
young and the elderly individual a "must"... Other crucial advices are stress reduction, plenty of
exercise, sufficient resting points throughout the day, (e.g, meditation) and last but not least,
smoking cessation.
Fig. 5: The health pyramid: a good basis is plenty of water, fruit and fiber, but refrain from excess of fats
and sugars (top of the pyramid). Exercise is essential and up to two glasses of red wine a day is fine, but one
should stop smoking as soon as possible!
Another important factor is once activity pattern both physically and mentally. Ageing of our
complex organism is in fact due to loss of complexity of various biological systems in our body
(increased entropy over time). In order to counteract this, we must put more energy into the system
in the form of cognitive stimulation, i.e. informational energy, which activates many biological
processes. It is advised therefore that elderly people actively accept new challenges in their life and
maintain much of their youngster lifestyle properties such as sports, sex and learning. Intentional
cognitive stimulation (i.e. special brain exercises, sense exercises, seeking novelty and excellence)
will add robustness to their planned positive attitude. The brain should therefore be forced to make
more decisions and to select the best option among a number of possibilities. An appropriate
selection itself creates information (Shannon’s reduction of uncertainty). Meaningful information
(knowledge, experience, wisdom, excellence), via expressive activation of appropriate brain
mechanisms, increases the energy available to biological processes that then improve repair and
maintenance, thus non-ageing.
Statistically, people who live according to these directions, may live 10-15 years longer than people
who do not, although there are exceptions to this rule which are due to individual genetic make-up.
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Also the psychological factor counts: people who are feeling old, become victim of a self-fulfilling
prophesy, in contrast to those who accept the challenges of life even after sixty and may feel
relatively healthy: aging is indeed is also something between the ears...The unraveling of the human
genome with its DNA and RNA, opened the door to revolutionary and emergent developments in
evolution. Examples are gene modification, gene replacement, gene transfection, improved gene
repair and protection. Even the cloning of individuals will become possible, at least in principle.
(see Fig. 6).
Genetic approaches
Genetic interventions in the humans are, by many, seen as a taboo item, but by others rather
welcome its potential blessings. This principle ethical divide, may lead to a crucial split in the
further evolution of humanity (See Greenfield, 2003, Chown, 2007, Post,2004, Goldsmith, 2012).
Fig. 6: Gene manipulation by the insertion of a gene (red) in circular DNA strands (plasmids), which is then
are used for the synthesis of a therapeutic proteins (bottom left). Right: Gene-control (activation on and off)
by protein complexes (transcription factors) that bind to the DNA promotor strand of a gene with in the cell
(inset lower right, red, blue and green structure).
Genomics and proteomics now are the "buzzwords" in the life sciences. Our genome with
approximately 22,000 genes, that code for the essential proteins of our cells, contains a sea of
information which, as shown above, is trapped in the cell nucleus. The DNA is composed of a chain
of nucleotides that are efficiently folded in a double helix, which, in turn, is packed in the
chromosomes in a sophisticated manner. The reading of the nucleotide sequence in each gene can
only occur when the folded double spiral can be unfolded on the spot and each triplet of
nucleotides, corresponding to a particular alpha- amino acid, can be recognized. Through the
reading of the entire gene, the individual amino acids are strung together into a specific protein in a,
for that gene specific, sequence. This protein will then fold into a three-dimensional protein
structure.
Any gene can thereby give rise to multiple proteins, either by partial reading of the gene or by
variations in the folding of the amino acid chains. This whole process is subject to strict regulation
by specific clusters of signal proteins that control whether a gene is really active or not (see bottom
right inset in Fig. 6). Genes can, in this manner, be turned on or off, and this pattern of gene
activations is different for each cell type. This creates the 200 different cell types in the body, all
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with a slightly different mix of active genes and thus their corresponding proteins. In other words:
liver, heart, muscle, - or brain cells do all have the same genes but not the same mix of proteins!
Fig. 7: A Cell with its organelles (above left) uses oxygen that as a byproduct produces reactive oxygen
species (free radicals). Oxygen is needed for cellular metabolism, but the reactive oxygen species, are
damaging DNA and proteins that, on a daily basis, makes many repairs needed, (bottom left). If repair does
not keep pace with damage, ultimately severe tissue damage is produced and loss of function of organs and
joints may occur.
It became clear also that environmental influences are "felt" by cells through modification of their
gene expression. For example, major stress causes the production of stress hormones that in turn act
on the genes of certain brain cells such as neurons. Specific genes in these cells undergo chemical
modification (for instance by methylation of DNA) and thereby are turned off, so that the
corresponding proteins are no longer produced (Jablonka, 2006). Consequently, gene expression is
changed and cellular functions, as related to the particular proteins, are modified. Such changes can
even be passed on to the next generation because they also occur in the germ cells of the particular
individual. This newly discovered process is called epi-genetics and implies that the state of our
organism is not only determined by our genes perse, but also by the influences of the environment
via the individual gene expression. For example, it became clear that Holocaust victims, exposed to
chronic stress indeed can pass certain behavioral patterns on to their children.
One of the disturbing facts of life is that we finally will end our life due to the fact that we inhale
oxygen! Although essential for cell metabolism and the production of cellular energy, the major
drawback is that we thereby all produce very reactive oxygen species (radicals) that react with
essential cell components, finally leading to dysfunction and death of cells (Fig. 7). DNA repair
(500.000 repairs per cell per day), can finally not cope with this damage, since the quality of the
cellular repair machinery also becomes affected.
The whole process of gene expression, regulation and repair (Fig.7) is much more dynamic and
variable than previously thought. The Darwinian evolution mechanisms, such as random DNA
mutations coupled with a "survival" -directed selection of the variants of these genes, proved to be a
rather primitive model. It should be stressed that diseases are often based on abnormalities in more
than one gene and that such aberrations may also depend on individual gene expression, as
influenced by the adopted lifestyle and behavior of the patient! Thus disease control may not only
require the correction of multiple gene functions or their products (i.e proteins), but also an
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adaptation of living conditions and/or psychic stability! (Best, 2012, Post, 2004, Bishop, 2010,
Kirkwood, 2011, Lipton, 2005).
In practice, immortality is taken to mean not an eternal life perse, but rather an indefinite lifespan,
i.e. a lifespan without a predetermined end, and thus the abolition of involuntary death due to
ageing. In addition, it is taken to mean the continual absence of significant age-related pathology.
Instead of accepting that our cells are programmed to die, it should be investigated if hidden (nonexpressed) genes are present that code for longevity. If there was a way to activate this 'something'
then human biological immortality would be possible. If there were one or more genes that code for
immortality, and these may have been inactive for millions of years: they would have mutated over
time and eliminated into oblivion. Take, for example, the genes for developing a tail. This ability is
encoded in the fetal development and represents an active gene system also in humans. However
new genetic controls have been added during evolution to overwrite them. The genes exist but their
action is suppressed or inhibited. Human embryos have tails when they are a month old. Then the
tail regresses and disappears through action of newer genetic controls, causing apoptosis and
remodeling. If we would be able to activate the supposed genetic ability for continuing life, then
this genetic system could be manipulated to operate along a different option, which may lead to a
life without a pre-determined end (Kyriazes, 2013).
Scientists are also working now on the "genetic design" of drugs. For instance, chemicals or
therapeutic proteins are screened for binding to and inhibiting of gene components or gene
products. The latter can be a protein that in the cell is engaged in the metabolic network that is
dysfunctional and may be the cause of the disease. In this manner the function of the diseased cell
may be favorably adjusted (for example the relaxation of blood vessels in patients with abnormally
high blood pressure or by influencing specific factors by which the folding of proteins is improved
(for example, in Alzheimer's disease). However the hunt for the "disease genes", that are supposed
to be the very cause of a particular disease appears extremely complex and the related costs are sky
high (800 million Euros for each new drug that comes to the market). Nevertheless, scientists still
await spectacular developments in this field.... Life extension by genetic modification certainly lies
in the future as a reachable goal (Fig. 8). Yet, gene manipulation should always be accompanied
with proper societal guidance and be preceded by a well-organized public debate about what is
ethically justified on the long term (De Grey, 2007, Post 2004, Weiner, 2010).
Fig. 8: In-utero gene transfection (left) and gene therapy to produce a therapeutic protein (right).
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This is also true for the genetic aspects (for a number of relevant genes in this respect, see Fig. 4). A
likely development is the modification of gene expression or even the addition of foreign genes that
may enhance normal bodily functions. For example, there are current thoughts on the injection of
viral carriers with a specific gene that promotes the production of a certain type of muscle cell that
can largely improve the performance of athletes...., doping in the future may therefore be genedoping!
Survival by cryopreservation
Programmed freezing and preservation of deceased individuals (called cryopreservation), in order to
revive such individuals at a later time, when a definite cure for their disease is available, is already
initiated by a specialized organization in the USA that, until now, keeps about 40 bodies in liquid
nitrogen storage compartments (see Fig. 9 and link Cryonics). This requires a programmed freezing
technology and injection of preservation fluids to prevent freezing damage to tissues. Even more
complex is the de-freezing stage that still have to be fully mastered in the future. Anyway this
seems a quite silly endeavor, since after all, it would be sufficient to store some individual stem
cells in order to clone a young and healthy individual (see later). Even if this extremely costly
procedure would be fully accomplished and the particular disease could be handled, the particular
individuals would wake up in an environment that would be completely different from the previous
one (relatives, societal conditions) so that, through the necessary adaption to the new situation,
much of the original individuality would be lost.
An obvious complicating factor in the therapeutic intervention with drugs in our organism, is the
sheer multiplicity and redundancy of cellular processes in each of our cells. Intervention with a
single process by drug therapy will inevitably lead to either compensation reactions or to subtle
changes in the whole organism that may be detrimental to the individual on the long run. We have
no less than 100 million times a million cells in our body, which somehow work perfectly together
and during the life also are replaced regularly! Each cell is, in itself is already a complex machine
having at least 100.000 different functional proteins. About the fine regulation of this beautiful
multi-cellular system we still are largely in the dark, although considerable progress have been
made in the study of processes leading to aging and death in the last 20 years.
Fig. 9: Survival of the individual by cryopreservation of whole body or brain: a good idea ?
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Cell rejuvenation
Recently it became known that removal of senescent (outdated) cells, that remain intact for too long
in the body during aging, can yield major improvement of health. By programming of immunecompetent cells that selectively destroy such cells, a dramatic rejuvenation of the respective tissue
can be attained. Senescent cells, in between healthy cells (Fig 10, below, in the center) release a lot
of harmful inflammatory substances that negatively affect the quality of life. The inset at the bottom
of Fig. 10, shows a (relatively large) mouse after such an immunological treatment compared to an
aged non-treated animal (Naylor et al, 2011,Treadwell, 2006).
Could the life prolonging effects of calorie restriction and removal of senescent cells be mimicked
by the action of appropriate medicines? Last year, research convincingly showed, for the first time,
that a drug could extend life span in mammals. The particular drug is rapamycin, a medicine
prescribed to prevent rejection of transplanted organs. Despite its reputation as an immune inhibitor,
earlier studies with worms and flies suggested that it might mimic the anti-aging effects of calorie
restriction. And when researchers at three different U.S. labs gave it to late-middle-aged mice, the
results were stunning: the life expectancy of the aged males was boosted by about 20 percent, that is
on the average more than 15 years in human life span. It works by blocking a single protein – an
enzyme called TOR or ‘target of rapamycin’. TOR is the center of a massive signaling network in
the cell, TOR influences how cells grow and divide, how rapid proteins are manufactured from
RNA, and how unwanted components are recycled in the disposal units of the cells called
lysosomes. Blocking TOR by rapamycin type of drugs, increases removal of dysfunctional proteins
and organelles in cells, as well as helps to destroy cripple (senescent) cells so that damage by these
tissue components is restricted and the aging process is greatly retarded.
Rapamycin’s new powers were discovered as part of the National Institute on Ageing Interventions
Testing Program, an ambitious research program that tests potential life-extending chemicals in
mice. Green tea extract, aspirin, resveratrol (found in red wine) and simvastatin are all potential
candidates, and it is quite possible that other already existing drugs could have life- prolonging
effects. Supporting this idea, is the finding that metformin, an anti-diabetes drug, that steadies
blood-sugar levels in people, clearly mimics the effects of calorie restriction on gene activity in
mice. It has been shown to extend a healthy lifespan, even in non-diabetic rodents. More than 50
million prescriptions for metformin are written annually in the U.S. This means the anti-aging
revolution may already have been accidentally launched! Years from now, we may discover that
long-term use of metformin by diabetics increase their healthy lifespan far more than can be
explained by its effect on their blood sugar levels. There’s already evidence that people on
metformin have lower risk of cancer, dementia, heart failure and other diseases of aging. This
suggests that such drugs, if proved safe to take chronically as preventive medicines, would have
unprecedented efficacy in ameliorating or warding off obesity-associated diseases, regardless of
whether they induce weight loss or not.
Would such interventions lead to a sharp rise of health care costs because people simply live longer
or would it rather spare costs because these older persons remain longer in a good shape?
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Fig. 10: Above: The "oxidative stress" hypothesis of aging. Cell damage occurs through oxidative reactions
on DNA and proteins by oxygen radicals (red dots) occurs especially in metabolically unstable individuals,
such as mice (upper left) and humans with obesity. Proper countermeasure is major calorie restriction in the
diet or removal of senescent cells (below, right).
The proof for the latter came out in 2003 in the New England Journal of Medicine. Analyzing
Medicare data, federal researchers showed that elderly people in good shape at age 70 — meaning
they had no difficulties performing tasks of daily living such as walking and shopping — could
expect to live up to 84 years, while after 70 they had average, cumulative health care bills totaling
$136,000. In contrast, less healthy 70-year-olds with at least one limitation in daily-living activities
could expect to live up to 81 years —three years less — yet had cumulative medical bills of over
$145,000 during their shorter remaining lives. Thus, boosting longevity with anti-aging medicines
might well lower Medicare expenses on a per-capita basis.
Conclusion: It is certainly not excluded that, even in the near future, combinations of gene therapy,
healthier lifestyle and appropriate medical interventions, may lead to a substantial extension and
quality of life (see the links for Engineered negligible senescence).
Stem cell therapy and cloning
Other examples, apart from gene transfections with life-prolonging genes, is the implanting of socalled stem cells into tissues of the diseased organism. Stem cells, prepared from embryonic tissue,
can develop into any cell type wanted. For example, diseased cells in the brains can in this manner
be replaced. For example, in the case of the fatal Parkinson's disease (see Fig. 11) promising results
have been obtained by local injection of stem cells that, in the brain, grow out to dopamine
producing cells (West, 2013).
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Fig. 11: Stem cells (grown on agar, below) and inserted into the brain by injection (left) or the heart (upper
part right): a breakthrough in renovation and repair of organs!
Recently it has been demonstrated that stem cells from the skin of mice can be manipulated back
into embryonic cells, and that using these cells a whole series of mice can be cloned (Fig. 11). If
such cloning technology would be available for the reproduction of man, a special kind of
immortality could be achieved that hitherto is only known from the world of micro-organisms like
bacteria. By activating four different transcription factors (Oct4, Sox2, Lin28 and Nanog) in
embryonic stem cells, induced pluripotent stem cells are produced in which the internal clock of
aging is reversed and the cells regain immortality through lengthening of their telomeres (see also
next section). Interestingly, it was shown that woman that smoke cigarettes suffer a considerable
loss of telomere length, whereas lower levels of omega-6 fats coupled with increased omega-3 fats
results in increased telomere length. The omega-3 boosting can be achieved by taking 1,500 mg fish
oil daily and is probably due to the inhibition of inflammatory cytokines. These human studies
indicate that it may become feasible in the near future to juvenile cells in the intact organism by
therapeutic agents (Liu, 2003).
De-programming of inborn cell death
Another possibility to do something about our limited life span, is the genetic reprogramming of
cells in our organism. The hard fact is that each of our cells (except germ cells) is programmed to
die after a certain time: our cells are restricted to up to 40-50 cell divisions in our life time. Our
death is therefore in fact built into our bodies…. From an evolutionary standpoint this is a useful
mechanism since it guarantees that our organism dies after having accomplished its reproduction
task. Also it stops senescent cells to get out of control. Cells in which this internal death mechanism
is disabled, for example, can turn into tumor cells, growing out to solid tumors that invade healthy
tissues and may spread throughout the body (metastasis)!
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Fig. 12: Telomeres at the end of chromosomes (green, top left and fluorescent yellow, top right). At each cell
division shortening of the telomere occurs, and the DNA chains will be less and less protected during each
cell division.. The telomerase is coded by the telomerase gene, of which the expression is normally low, can
be promoted through the influence of hormones like testosterone.
One of the processes that determine the life span of cells is the shortening of the so-called
telomeres, located at the end of each chromosome in the cell nucleus, that is associated with each
cell division (Fig. 12). Telomeres are repeated short strands of nucleotides at each end of the folded
DNA chains which are necessary for the DNA chain to stay protected against damage during cell
division (see links Telomere and Telomerase). At each division of the cell, this telomere becomes
shorter, until the cell can no longer repair the damage done, and consequently dies. Only one
catalytic protein, the enzyme telomerase, is able to rebuild their length. It is, except in our germ
cells (egg and sperm cells), poorly expressed in other cells in our body. Thus, it seems obvious to
bring (transfect), the gene encoding the telomerase artificially in our cells, or to activate the
dormant gene in the cell in order to locally produce telomerase!
Activation of the gene for telomerase is realized via the associated promoter-gene (a type of on- and
off- switch, see Fig. 12) so that the telomeres can be, at least partly, restored. Sex hormones such as
estradiol and testosterone stimulate this promoter element, but the production of these hormones in
our body is unfortunately reduced with age... Recent research in mice showed that the telomerase
gene in that animal can be completely disabled by a technique called gene-knock out. These geneknock out animals, already at very young age, show severe signs of aging, such as abnormal
posture, hair loss, loss of sperm production, reducing the brain size, etc (see Fig. 13 and Jaskelioff
et al, 2010). Mice live only about three years and have a genome that resembles that of humans, and
are therefore very suitable laboratory animals for aging research, since in the relatively short life
span all stages of life can be studied.
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Fig. 13: The enzyme telomerase can maintain telomere length by the insertion of nucleotides (bottom left) at
the distal end of chromosome. Mice lacking the gene for production of telomerase, or mice in which the gene
is turned off, age abnormal rapidly. If telomerase in these animals is again reactivated, the enzyme is
produced again and stops further aging and even induces rejuvenation (big mouse with a glossy coat, top
right). The question is whether such a rejuvenation process may become feasible also in humans (bottom
right).
If one now injects a chemical that activates the promoter of the telomerase gene into these
artificially aged animals, telomerase enzyme is again produced, and the telomeres of the mice
extended. This not only stopped the aging of these animals but, to the surprise of the scientists, led
to a spectacular rejuvenation, with hairs and sperm coming back, while mobility greatly improved
and the brain of the animals becoming anatomically more normal (see Fig. 13). This animal model
demonstrates the importance of telomerase to counteract aging and even showed a major
improvement in fitness of these animals. Of course the relevance of this artificial model for humans
remains to be proven. Also it should be realized that there are multiple cellular mechanisms, other
than telomere function, which influence the aging process.
The pharmaceutical industry is nonetheless actively searching for selective telomerase-activating
agents and in fact there seems to be already one on the market (Fig. 14): an extract from the root of
a plant that grows in China. Astragalus is the active component, which has been shown to cause an
improvement of the immune system, which is probably linked to an extension of the telomeres in
the immune cells. Incidentally, many of the recommended "lifestyle" measures mentioned in Fig. 5,
have also be shown to produce a modest degree of telomere extension! Thus, telomerase activation
seems to be a logical target to battle aging. Yet the risk of this therapy is still too large because such
measures may also increase the chance of promoting tumors in the particular target tissues.The
solution here lies in the fine regulation of telomerase expression so that telomere repair occurs
without causing cancer! Proponents argue that activation of telomerase expression in the tumor cells
is already naturally high and therefore will not be further increased by the treatment, while the
positive effect of medicines such as Astragalus on the immune system even would improve cancer
treatment. The above-mentioned research is promising but awaits further proof in humans, among
others since laboratory animals have a genome that differs at least 20 % from humans (see
Andrews, 2010).
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Fig. 14: Left: Extension of telomere length by sex hormones and by an extract of the plant Astragalus. Also
the substance resveratrol, from red wine, may have a positive effect on telomere length, cellular repair and
protective mechanisms.
Conclusion: It is not inconceivable that in the next 50 years innovative solutions will be found for
increasing the life span of the human body and that in due course, by more sophisticated
biotechnological interventions and novel therapies, it will become possible to even renew the
organism to a significant extent (see links Biological Immortality, Life extension and
Rejuvenation). Despite solid reserve and skepticism on this claim(Vijg, 2008, Post, 2004, Shapin,
2000 and Goldsmith, 2012), one could speculate that about a century from now, people may look
back with pity on that dark period of humanity around the year 2000, when people still died at an
age of about 80 years...
3. Do we live on through our offspring or can we survive in cyberspace?
Continuation of our individual life is not yet possible but what about living on in your children and
their offspring? This is a popular, but not entirely correct, assumption. It should be realized that
children bear only half of the genes that are specific for the father or the mother and that their
descendants have, through the contribution of foreign partners, increasingly diluted genes (Fig. 15).
People resemble genetically much more their brother or sister, because they have indeed the same
genes from both the mother's and father's side. The genes and memes (personal mental properties),
that are so specific to an individual, are slowly fading away with each generation...
Digital immortality?
In recent decades, through the global computerization, a new experience space was created: the
colonization of everyday life with cyberspace. This development will inevitably change our
biological and cultural identity. An alternative for living on in the other, is that you live on, with
much of your personal information, in cyberspace. This is possible now by incubating yourself in
the virtual worlds of computer gaming or make your expression on Internet as large as possible....:
survival in cyberspace is up for grabs! (Kurzweil, 2005, De Mul,2002, Greenfield, 2003, Kaku,
2005 and 2007, and the link Second life).
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Fig. 15: Continuing personal life in your children (left) or attaining digital immortality (right)
The degree of expression of an individual on Internet provides in fact a kind of digital fingerprint. A
personal blueprint or autobiography is easily identified in this immense collective meme library
(Fig. 15). This strictly personal information is not easily erasable and will ultimately survive our
physical existence: digital immortality is, in this manner, indeed up for grabs (de Mul, 2006)!
Virtual reality fills our existence
Many, especially young, people have discovered the virtual world. Coming home from work with
everyday chores, they prefer the virtual reality: they are "avatar" in their own world where life is
good, human contacts satisfying and life more colorful and exciting. There they have a loved one,
besides friends and extensive possessions (Fig. 16). They play these games according to the rules
collectively agreed by the users: you can do almost everything but even here there are limits and
responsibilities! Interactive games and virtual worlds are offered nowadays on a digital square with
portals to practically any reality. Naturally, the world of flesh and blood is staying on, but the short
life that we are awarded can be much more filled and concentrated: lifespan itself is not extended,
but its intensity may at least be doubled! (see link Second Life).
Fig. 16: Double your life: dive in cyberspace!
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Will our brains adapt to this colorful exhibition: yes, this will certainly be the case, just like any
metaphor or story or image changes the wiring of ones overall neural network. Indeed, this
intensely experienced virtual world changes the very wiring of our brains just like the input of
walkmans, phones, television and the internet will do: all these peripheral apparatus are in fact
extensions of our brain. All of this, per definition, also modifies our individual self-consciousness,
because that arose through interaction of our brains with the environment: without such an
interactions we would not develop self-consciousness anyway! Will cyberspace become a factor in
the development of future human consciousness? The impact of these developments, on the long
run, may be a much more drastic than we can foresee now...Extrapolations of current technological
developments give clear indications for drastic changes in the evolution of future mankind. The
flow of information that assails us every day is overwhelming, and according to many, even
alarming!
Many parts of our bodies seem already replaceable by organ transplantation. Bio-chips that
continuously monitor our metabolic status will support such a development. Is the present world
conceivable without the computer, Internet and mobile telephone? We seem indeed to externalize
increasingly more brain functions and it follows that our brain will undoubtly adapt to the situation!
It has been claimed that we are already cyborgs (in silico bio-hybrids) (Clark, 2000, Fig. 17)! Will
this technology be our salvation, because we can ultimately substitute our fragile organism by
indestructible hardware?. In that case, there is no need at all to intervene in our genome in order to
extend our life span! Anyway, a parallel development of cyborg -technology and gene manipulation
seems obvious (Greenfield, 2003, Kaku, 2005 and 2007) and that these techniques may be finally
combined into a novel species: our “mind children” that may become our successors in evolution
(Kurzweil, 2005). It could be argued that the death of the individual organism is necessary so that
evolution will continue refining and increasing the level of complexity and intelligence through the
continual and progressive variability of the offspring. But it could also be argued that this may be
true for any other organism except for humans. It may be the case that modern humans represent the
highest point of procreative evolution, and that further refinement of intelligence through
procreation is now becoming unnecessary. Intelligence can now reach higher hierarchical levels not
through evolutionary variability (i.e. the evolution of the offspring through procreation) but through
personal development, i.e. a personal, self-centered developmental singularity process. If we could
indeed be programmed to live indefinitely, the hierarchical progress can develop through perpetual
learning, experience and intellectual sophistication which can continue to evolve in the same
individual. Organisms with lower intelligence must indeed follow the path of death/rebirth (as
required by the Disposable Soma Theory) in order to attain higher complexity through natural
selection, whereas such modern humans have now attained the highest possible intelligence level
afforded by procreative evolution, and do not need further development through this particular route
(Kyriazes,2013).
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Fig. 17: Artificial intelligence and robot science: a necessity for mankind in the future to cope with
an excess of information and technology!
It is important that we think thoroughly about these possible developments, in order to keep destiny
in our own hands. For example, "science fiction" literature is a useful reflection of such projections
of the future, because in this art the incredible becomes reality and a framework is created to
analyze social developments in its ultimate consequences. These projections of the future, in turn,
affect the existing science and art as they have done in the past. Who does not know the examples
of visionaries like Leonardo da Vinci, Jules Verne, George Orwell and Isaac Asimov (the first robot
laws). How strong is the influence of our projections of the future on actual development? Are the
films Star Track, AI and I Robot interspersed with virtual images or do they represent a "selffulfilling" prophecy of the future of humanity? Yet, the fear that robots will become conscious and
will overpower a weakened mankind is a misconception: we will have to collaborate with artificial
intelligence in order to cope with the many new challenges (see Fig. 17).
Is in the future the human organism replaceable?
Each human cell is, as mentioned earlier, in itself a complex machine that is programmed to a
relatively short lifespan. In addition many imperfections have evolutionarily slipped into the human
organism. Impressive is the sheer multiplicity and coherence of the hundreds of thousands of
cellular responses in each of these cells. This also applies to our brain. In the 100 billion brain cells
(neurons) in our brain self-awareness is manifested as a virtually unexplained phenomenon. Will it
become feasible in the future to design a completely new organism on the basis of synthetic biology
and / or cyber technology? Can our personal autobiography and self-awareness be "uploaded" in a
less ephemeral hybrid life form or in advanced robots? (Kurzweil, 2005,Tipler, 1994, Moravic,
1999).
Depth scanning of the brain and "uploading" of brain activity patterns up to a complete memory in
advanced computers can be an ultimate goal in the distant future. Would it be possible that our
"mind" eventually will feel more at home in a reliable machine instead of the vulnerable and mortal
human body? In particular for nanotechnology there could be a role here (see Fig. 18). It will, at
least according to some experts, become reality in the coming 200 years that super small "sensors"
injected into the bloodstream will be engineered to pass into the brain or other tissues and organs of
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our body, with the aim to monitor relevant cellular functions. This, includes scanning of the whole
circuitry in our brains. Such nanobots are instrumented to transmit this information to a remote
machines that than maps our personal profiles at any time on a continuous basis.
All of these points are seriously considered in the field of "Transhumanism" science. Robot
technology and current research on artificial intelligence indicate that if this trend continues, within
50 years, home computers will be built with the capacity of the human brain and may easily contain
the entire global bibliography, implying everything that ever have been written or printed!
Fig. 18: Scanning of neuronal brain networks (inset below), using nano-sensor technology that enables
uploading of individual information (inset top right). Here a so called nanobot is depicted that selectively
attacks dangerous cancer cells in the bloodstream.
This will be combined with the building of self-learning computer systems, going through the same
evolutionary process as the human brain, but in a fraction of the 100.000 years that the humans
brain evolved. In this manner incredibly intelligent machines will be created (Kurzweil,
2005,Tipler, 1994, Moravic, 1999).
In general, the societal impact of this development will be astounding. If we realize that even a
technical failure in the booking computer of an airport, nowadays poses a huge chaos, it is clear that
to deal with the complexity of our society, our future world will be largely run by artificial
intelligence. An interesting question is whether that kind of artificial brains will be aware of
themselves and of the environment with which they interact. Will people become a kind of extended
robots or will robots evolve to human-like machines? (Fig. 17). Will robots be able to develop
empathy and be programmed to act as our best friends, or will they instead become a potential
threat as pictured in well-known SF books such as “2001, A Space Odyssey” and movies like “I
Robot “, and the "Terminator" series?
And how will the future world look like thousand years from now? It should be realized that this
technological development exhibits an exponential nature: in the 20th century the knowledge
doubled every 10 years, now it doubles each year! (Kurzweil, 2005) The conditions at the end of
this millenium will greatly surpass our wildest dreams. Anyway, It may well be that the
development of artificial intelligence will prove to be an ultimate resort in the cascade of
information that will engulf us: the computer /robot may become even more than our best friend: an
indispensable instrument in survival of the human race…
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4. The physics of the future and its implications for immortality
In the foregoing it was assumed that the individual life is finite, in spite of the advanced measures to
prolong life that will become available: death seems ultimately unavoidable. However, there are
theorists, such as some quantum physicists, who at this point come to a very different conclusion:
namely that dying, in fact, is impossible! Our body cannot escape its demise, but according to them,
the information that determines our overall personality and continually reflects our lives, will
remain: the law of conservation of information.
This idea is, as mentioned before, borrowed from modern physics, especially quantum physics.
Although at first glance it seems an unreal idea, it is perhaps somewhat more compelling when one
realizes that what we perceive of the world is likely very limited and forms a very inadequate
representation of reality! In the underlying coherent reality (see Fig. 19), which is described by
quantum physics, the preservation of information is a prerequisite. Therefore, in the framework of
this essay, it makes sense to discuss these scientific developments in some detail (Forberg, 2006,
2007, Greenfield,2003, Capra, 1996, Lanza, 2012).
In the 20th century the standard model about the structure of matter and its building blocks, the
elementary particles, was created. This model at the micro level and the accompanying quantum
theory, however, were not consistent with the description of the macro world of the Universe as, in
particular, is described in Einstein's theory of relativity. There are now desperate attempts to
develop a "theory of everything", that should adequately describe both aspects. One example of this
is the String theory or, even better, its successor: the M-theory. The basic idea of the String theory
is, that not the real elementary particles, such as electrons. protons, photons and quarks, are the
building blocks of matter, but rather much smaller elements that can best be described as a sort of
strings that can vibrate at different, discrete, modes. Each of these different vibration patterns
corresponds to a particular elementary particle. This implies that at the smallest physical level, even
our brain, is an assembly of vibrations!
In addition, quantum physics tells us that particles may at the same time behave as oscillations
(waves), by which they can interfere with each other and can produce a sort of mixed waves, called
superpositions. The structure of reality therefore seems much more flexible than thought on the
basis of solid particles. Moreover, particles that belong to each other, in term of their properties
(e.g. their polarization and rotation or spin) are always linked even over huge distances: if you the
change the spin of one particle the paired particle spin is altered too. This strange phenomenon was
called “quantum entanglement”.
That such particles are somehow intertwined does not mean that they are exchanging signals, but
that they, in one way or another, are correlated. This was for quantum physics such as David Bohm
and many others, a reason to assume a "quantum wholeness" an idea that really means that
everything in the universe is connected "entangled (Meijer, 2012, Meijer and Korf, 2013). This
entanglement of everything cannot be detected directly or felt by us. Our individual consciousness
is so dominated by the overwhelming sensory input from our senses that we are rarely really aware
of this kind of connectedness. According to Bohm, such hidden phenomena are due to fact that they
are part of an underlying quantum information field that is present always and everywhere (thus is
non-local) and that, according to Einstein and Minkowsky, exhibits a four-dimensional structure
since it contains a complete time dimension: past, present and future are represented in this domain.
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Quantum uncertainty
Wave-interference
Wave/particle duality
Foton(en)
Quantum Physics
Quantum entanglement
De-coherence/Coherence
Superpositions
Fig.19: Elements of quantum physics: uncertainty of position of particles, wave / particle duality as
demonstrated in the double-slit experiment (upper part),as well as entanglement (non-locality) of particles at
great distances, the phenomenon of coherence/decoherence and superposition of waves (lower part).
Such a quantum field does not exercise influence through the use of forces, as is the case with
electromagnetic fields, but does so through the exchange of energy that is continually reallocated in
a dynamic process. Building and decomposition of matter are, in fact, caused by absorption and
release of (virtual) photons and matter can thus, more poetically, be envisioned as "light captured by
gravity." The virtual particles of the field can in this manner also provide an energy exchange
between the physical reality and the non-zero local field to which they belong (Fig. 20). Even the
force of gravity, a yet poorly understood phenomenon, may be related to this field, because it has a
retarding effect on the movement of material: so-called inertia. Both aspects also underline the
possibility suggested by Penrose that quantum gravity is instrumental in the capture of quantum
information in our brain (Meijer and Korf,2013).
The infinite consciousness: an information field?
This particular quantum energy field is also seen as a giant hologram (see, for instance, Steven
Hawkins and the Dutch scientist Gerard van 't Hooft) that permeates everything in the universe. It is
considered by the physicist and systems theorist Laszlo as an universal information field (Laszlo,
2006). Consequently, each of us is supposed to be in contact with the field through wave
interactions. So we are in fact connected to a general energy field, which penetrates our bodies
constantly (Meijer, 2012). The information exchanged is not only used for a deeper form of
coordination but probably also for the creation of meaning. A number of prominent scientists
scientists who laid the foundations for the hypothesis of the quantum brain: the Nobel Prize winners
Wigner (quantum physicist) and Eccles (neurologist), the quantum physicists Bohm, Stapp,
Goswami and Wolf, the neurologist Pribram and mathematician Penrose, initiated the idea that our
brain may functions as an interface between the individual and the collective consciousness that is
stored in this quantum field.
Ervin Laszlo, 2006, states that the universe, in this way, exhibits a kind of universal memory and
that all experiences are stored in, what he calls, the Akashi field, an term that is also encountered in
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the Eastern religions. The basis for the existence of this field derived Laszlo from the, so called,
torsion fields / vacuum domains previously by Russian researchers.
Fig. 20: Left: The universal, all pervading "zero energy field" as a vacuum with fluctuations of quantum
waves or particle/antiparticles (insets right). Through superposition and photon polarization) information
storage is possible. Two plates at a very narrow distance (left below) show attraction since the virtual
particles outside can exert more pressure than the spatially expelled particles inside (the so called Casimir
effect that demonstrated the universal presence of zero point energy). The anti-particles travel in a reversed
time mode.
Recent experiments showed that teleportation of particles is based on sending complete information
on that particle over a wide distance, by which at that distant site a solid particle is created: thus
matter arises from information. The renowned scientist Anton Zeilinger therefore concluded that
information is more fundamental than matter and energy. It became also clear that such an universal
information field can also be seen as the source of the origin of the Universe (see also the link to”
Information Universe”, in the references).
In the next sections we will explore the possibility that also personal information is stored in this
domain and can be instrumental in the realization of an fundamentally different modes of
immortality. In other words immortality could be considered as the conservation of information.
5. Transcendence of the individual self
This section addresses the, so called, transcendental phenomena in human experience. Detailed
investigation shows that also in this area scientific research of high quality has been done in Europe
as well as a great number of top universities in the USA. With the term " quality research” we mean
that it is properly designed research with sufficient built-in controls, professional statistical analysis
of data as well as publication in peer-reviewed journals. Yet the recognition for this ground
breaking work by "mainstream" science is often rather thin, because one tends to deal with the
particular results in a rather conservative way on the basis of usual reductionist and materialist
frameworks.
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Fig. 21: Transpersonal experiences: the researchers (bottom right), the techniques for them to arouse or
experience (top right) and the postulate of the internal filters in our brains (top left). Personal information
from a supposed quantum field, is experienced as clairvoyance or described as an inner voice (called
“Daemon” in classical Greece philosophy).
Scientists who upfront reject scientific results, that do not belong to the (temporary) consensus, are
evidently counterproductive in the advance of science perse. When in this area “the wheat is
separated from the chaff” (and that is needed in all areas of science), it is discovered that there is
overwhelming evidence for the occurrence of so called extraordinary experiences (anomalies, see
Jahn and Dunne, 2007 Radin, 2006, 1996). It is therefore worthwhile to keep these phenomena
against the light, in the framework of modern physics, in order to see what they mean for our
current view on the world and how we could get a finger behind the mechanisms that are in play
here. It is also of great importance for science in general to seek the fringes of its disciplines,
because historically it often appears that the real breakthroughs occur especially in these areas (Fig.
21). Of note, the scientific debate between materialistic and idealistic worldviews runs as a red
thread through the history of science and philosophy, and, for example, is now prominent in the
major discussions on the nature of consciousness, as well as in the dialogue on the relationship
between science and religion.
Religions have had a very unbalanced role in the cultural evolution of mankind: useful unifying
visions of society to the most horrific acts that humans have ever committed. Modern brain research
indicates that religious and spiritual experience is associated with various brain structures and that
immanent evolutionary spirituality is deeply embedded in human nature (Carter, 2013, Lanza, 2012,
Wolf, 2008, Peake, 2008).
Whether individual consciousness is retained in any shape or dimension beyond death is currently
intensively discussed in relation to various types of transpersonal experiences, in near-death
experiences (NDEs), mystical experiences and in "channeling" (receiving very complex
information, large texts or images from an unknown source). Is our brain somehow a signal receiver
for information from a "superconscious" domain (Jahn and Dunne, 2007, Peake, 2008, Radin,
2006)?
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Consciousness beyond space and time in the Near Death Experience
In line with other Near Death Experiece (NDE) investigators, particularly from England and the
USA, the Dutch cardiologist van Lommel, 2001, 2007, proposed an own vision on consciousness.
In his book 'Endless Consciousness', he argued that consciousness may not really an
epiphenomenon of the brain, but is rather an autonomous phenomenon, independent of the physical
body. In such phenomena as consciousness, we must also bear in mind that there is a continuous
exposition of our individual consciousness to the outside world: without the imprint of the outside
world, personal consciousness could not arise anyway. Our brain should therefore always be seen in
relation to a flow of information from the other parts of our body and also the signals we receive
from and send away to the world around us. This flow of information includes the interaction with
the invisible, but ever-present, quantum wave world, that after all is as real as the material world of
particles: matter and mind are complementary aspects of a unified reality.
Ultimately, all our senses are based on only electrical impulses propagated through the nerves to the
brain, where they activate networks of neurons and then somehow are translated into a perceptions.
Sight, hearing, taste, smell and touch are thus, in materialistic terms, fundamental similar, because
all these different sensory experiences, arise from electrical stimuli. However, it is still entirely
unclear how our individual consciousness and self-consciousness become manifest and what the
basis is for our subjective feelings such as our individual perceptions of color, smell and sound
(called qualia). Many scientists today support the hypothesis that this kind of experience is not
merely based on the sum of neuronal activity, etc. Rather the required communication between
brain areas (`binding`) is the result of quantum coherence and quantum entanglement in the brain
and consciousness is, at least, partly caused by the so called wave / particle duality, implying that
the elementary particles that constitute our brains are also part of a wave world as postulated in the
quantum theory. Through this quantum wave aspect, according to this hypothesis, non-sensory
information transfer to the brain can occur from a universal wave field. Recent research showed that
the quantum world is not only relevant at the micro level, but also belongs to all of our everyday
macro world (Fig. 26, 27). Quantum phenomena were recently shown not to be solely important for
the atomic level. Quantum effects were demonstrated in living cells including the essential process
of photosynthesis as well as in the brains of birds in the detection of geomagnetic fields during bird
migration. Therefore it is quite well possible that quantum fields played a role in the becoming of
living organisms, and are instrumental in the coordination of 100 trillion cells that constitute our
bodies (Meijer and Korf, 2013)
Common features of NDEs
The research showed that about 20% of patients in cardiac arrest had a mild to profound near-death
experience. The experiences during a near-death experience appear to be quite universal and have
been reported worldwide. The experience seems only modestly dependent on age, gender, cultural
background and religion of the people involved. It happens both to believers and atheists, and also
to people who have no prior knowledge of the NDE phenomenon (Van Lommel, 2007, Carter,
2012, Elsaesser, 1997).
The common characteristics (Fig. 22) are: traveling through a tunnel toward the light, a
retrospective view on the life and encounters with deceased loved ones. Most patients experience an
expanded awareness: thoughts seem to go faster than during normal waking consciousness. It
appears, in many cases that some kind of access is felt to an omniscient consciousness that answers
every question that a person on earth has ever asked. It is scientifically proven by several
researchers that these experiences occur during the period of cardiac arrest in which both brain
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activity and the heartbeat are not measurable. The ECG and EEG of these patients do show a flat
line on the monitor and activity in the cortex and brainstem are not detectable. According to current
scientific knowledge, it cannot be explained that patients during a near-death experience can see
and hear more clearly and apparently have an expanded consciousness. In contrast, one would
rather expect a more limited consciousness. All conventional scientific explanations given for the
near-death experience, such as oxygen deficiency in the brains, hallucinations, drug use that can be
accessed from the recorded data can be altogether rejected.
For example the often raised argument that the loss of blood supply and a flat EEG does not exclude
that somewhere there is still little brain activity, especially since an EEG is predominantly a
recording of the electrical activity of the cerebral cortex, misses the whole essence. Because it's not
about whether there might be some neuronal activity to measure, but whether there are specific
forms of brain activity, that according to current neuroscience are considered necessary to
experience such a clear consciousness. In vivid dreams of this type there are always intense brain
activities that can be easily determined. And precisely these specific forms of brain activity in the
EEG in patients with cardiac arrest totally disappear during a NDE experience.
Recent developments in physics in relation to NDE
The phenomenon of near-death experience also raises deep philosophical questions. This experience
shows that consciousness, under those circumstances, apparently can observe a physical world
without involvement of the normal senses. There are even documented cases in which during the
near-death experience, observations were made by the patient at great distances from the body, that
later were verified as being absolutely correct. The question arises whether our normal sensory
perceptions act as a filter for this kind of conscious extra-sensory perceptions. From the testimony
of persons reporting NDE, it is inferred that their perception during near-death experience is faster,
broader, more realistic and more pure of nature than during an ordinary dream. Also during the use
of certain drugs, meditation and rapid change of gravity (falling down and traffic accidents), "out of
the body" and NDE-like experiences are generated, but they do not have the quality and character
content of the expanded NDE experiences as they were in many cases reported (see Fig.22).
Recently an interesting study was presented (Venselaar, 2011), in which the NDE is described fully
physically as a 5- stage process that includes a) separation of photonic consciousness from the body,
b) a journey to a tunnel of light after strong contraction of the particular information, involving
mini- black hole and wormhole modalities and observation of cosmic structures, c) being at the
presence of light at a border, having a life review and experiencing specific light shifts, d) a
subsequent return to the body and e) final unification with the physical body. Another recent study
(Bokkon et al, 2013) confirms the potential role of bio-photons in several aspects of NDE, in
relation to intrinsic visual perceptions and imageries as well as self-consciousness that may involve
low-energy quantum entanglement of bio-photons in interaction with the photonic zero-point
energy field (ZPE). Bio-photons are constantly produced in the entire organism at the cell
membrane, and within the cell in mitochondria and DNA, including the brain, the latter due to
Casimir-like conversion of virtual photons of the ZPE to real photons, at the synaptic cleft of
neurons, providing an ultra-rapid communication system in the entire organism.
“Life after life” is pictured as a being of light, due to the fact that damaged or dying atoms of our
physical body release countless photons (light energy). Since our daily consciousness is connected
to the brain, these exotic photons, are supposed to be transformed into another broader transcendent
consciousness, in which such photons are indestructible. The particular photonic body, in this
theory, may be capable to 'carry' information about who we were and are.
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The panorama of life: better than memory....
Impressive is that during a near death experience, the patient is confronted with a full and bright
panorama of his/her entire life, in which he/she is not only relives the life from his/her own ego
perspective, but also from the perspective of each person with whom one has been in contact during
one’s lifetime. This experience from the perspective of the other, according to many of the NDE
patients is complete, including the thoughts and feelings of every person who crossed ones path in
life. Of note, the majority of NDE witnesses, subsequent to their profound experience, live a more
conscious life, being more open to others and more interested in the big questions of life (see Fig.
22).
Fig. 22: The general components of a Neat Death Experience
Is a NDE only due to previously stored images in the brain?
The extraordinary near-death experience of Vicky Noratuk showed that even blind people can see
again during a near death experience! From her birth she had a shrunken eyeball and optic nerve
and an undeveloped visual cortex. So even if there would be a yet unknown activity of the brains
during the near-death experience, she did not possess a healthy sense organ that could transfer her
visual impressions to her consciousness through the brain, nor a memory for detailed images. After
she had her experience, she described this as "it felt like the place where all knowledge is". A
faithfully executed study with 31 similar cases of blind vision (Ring and Cooper, 1997), revealed
that blind persons, including those blind from birth, do report classic NDEs of the kind common to
sighted persons. Further citing the article: “Thus, what we have here is an adumbration of a process
that begins with Mind, seemingly fully independent of brain becoming self-referential, that is,
becoming identified with consciousness itself, and then converting this noumenal consciousness
into a dualistic modality that generates the familiar phenomenal world. What we have called
transcendental awareness is at least the beginning of the reversal of that process by which, even
though the traces of an everyday dualism remain, the individual is enabled, however temporarily, to
experience the world from a perspective independent of brain functioning and the operation of the
senses. Each of these theories formally entails such a state of awareness, and specifically in blind
persons, during NDEs or OBEs”.
The modern NDE research thus leads, just as investigation of reincarnation (see below), to the
hypothesis that consciousness continues to exist in some form after death. Death, according to this
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hypothesis, is only an illusion. It is, in this consideration, only a transitional state to another form of
conscious life, but without the experience of a physical body. According to some quantum
physicists, such as Alan Wolf (1996,1999, and 2008), and Hameroff (2013), dying is, more
precisely, not a transition to another phase, but rather every individual is at every moment of ones
life already represented in the non-material dimension of the aforementioned quantum information
field (Fig. 23). In other words, in this theory, conservation of individual information is a continuous
process and is permanent.
Reincarnation: an indication for life after death?
For a possible survival of personal information after death, there are also indications in the many,
now documented, reincarnation reports of children. Children from very different age, sketch
spontaneously, without any special cause, life histories of people that have been proven to be
completely unknown to them and about particular persons deceased long before their own birth, and
that in a staggering detail. Globally ten thousands of well-documented cases have been thoroughly
examined, often dealing with children at an age of 5-10 years who spontaneously explain that they
have lived another life and have been another person. Such suggestions are always met with much
skepticism and sometimes received with complete disbelief, which is obviously quite
understandable (see links Reincarnation and link Ian Stevenson).
However it encompasses many cases with descriptions in an incredibly detail, outlining various
aspects, such as the exact location of the residence of the deceased, the layout and decor of the
house, hidden objects, knowledge of family of the deceased and personal characteristics thereof,
including the character of the deceased. These stories were, inter alia, thoroughly verified by the
renowned historical researcher Stevenson (see link Ian Stevenson) and in many cases found to be
completely in line with historical reality (Phipps, 2012, Peake, 2008, Carter, 2012, Elsaesser, 1997,
Fontana, 2005)! All this, even in cases where the child had never been in the described country and
did not have any contacts with people out of the particular area nor with family members of the
deceased. In some cases these stories also report the fluent speaking of a second language (of the
deceased person) by the child or for example, without any exercise, playing a musical instrument. It
is as if the skill of the deceased is directly transferred to the child.
A critical discussion of these puzzling phenomena are found in references of Braude, 2003 and
Carter, 2012, and link to Reincarnation. There are, according to the authors, apart from fraud, that
often can be simply excluded, two possibilities: either the child receives somehow exact
information from another world in which the deceased in some modality mentally persists (survival
hypothesis) or it is due to a telepathic transmission from a still living person, who in that case
should have detailed information on the deceased and be able to transmit this telepathically (the PSI
hypothesis). In the above mentioned, well referenced and well-researched, books, it is concluded
that the survival hypothesis, as related to these reports, seems much more supported than the
assumption of telepathic contact between the child and the particular person involved. It is
hypothesized that a general information field may be instrumental in the reincarnation process due
to storage of individual information and potential resonance with a future entity (Fig. 23).
The respective authors conclude, after really exhaustive and scrupulous research, that in a manner
not understood, some people (or detailed data on them) persist, at least temporarily, after their
death. This, in some way, leads to the transfer of personal information to young children that
become beware of this information and interpret it as their former life (Braude, 2003 and Carter,
2012, and link to Reincarnation). It is clear that we arrive here at the borders of knowledge and that
we experience something that is far beyond our human intellect. Nevertheless, the phenomenon of
children report is, in itself, established in thorough research, and despite the absence of a
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satisfactory explanation, is recognized as such in scientific circles, albeit without the notion that this
represents a process of rebirth or reincarnation. An impressive report of a “skeptic” scientist is
depicted in the link about reincarnation, that provides an interesting view on this possible modality
of immortality (Phipps, 2012).
The Construction of Reality
Big Bang
Vibration/Wave
superpositions
non-locality
uncertainty
Matter
Time/ Space/ Info
E = h.v
E= m. c^2
elem. particles
entanglement
inform. network
Quantum Energy
Universum
inhabit. planets
entropy
syntropy
biol. evolution
Information Field
Quantum Field
zero-point energy
brain as interface
Universal Consciousness
All Time
Individual
Consciousness
culture/memes
mental evolution
free will /choice
P
S
I
/
E
S
P
Human
Intelligence
evolution brain
Implicate Order
Rebirth Cosmos
Ω Information
Observers /
Participants
Re
in
car
nat
ion
Intelligent Life
humanity
science
natural Laws
Artificial Intelligence
human/technology
Fig.23: A tentative scheme to picture the construction of reality, with a central place for a Universal
Consciousness, or Quantum Information field (black). in which all time is laid down and that is considered
to be the source for and final destination of our Universe. The Big Bang gave rise to the material (right part)
and mental (left part) unfolding of information. These complementary aspects of reality lead to human and
machine intelligence, by which the Universe is able to observe itself in ever increasing detail. PSI, ESP as
well as BDE/ reincarnation phenomena reflect the dynamic interaction of individual and universal
consciousness with our brain as interfacing instrument. The collection and compression of all final
information leads to rebirth of our Universe in a subsequent version at the omega point (see section 6 and
7).
The notion that can be inferred from the sections above, namely that consciousness of all living
entities belongs to a collective "web of information", should implicitly be supplemented with the
reverse side of this concept: that individual consciousness, through this interfacing, is just as much
an expression of the universal (nonlocal) consciousness. In this respect we are, according to this
quantum concept, truly part of the unity of nature, as Spinoza already postulated (Fig. 23).
Paranormal phenomena: extra-sensory perception of information from another domain?
The quantum consciousness models treated above may also be instrumental in the explanation of a
number of so called transcendental experiences. Examples are, the fairly normal, (trans)-personal
feelings of intuition, serendipity, synchronicity as well as feelings of "high", and dreams (Fig. 23
and 24). But also more "transcendent," or paranormal aspects such as channeling, out of body
experiences and near death experiences (NDEs) might be discussed in this framework (Radin, 2006,
Jahn and Dunne, 2006, Braude, 2003, Carter,2012).
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Fig. 24: Various forms of extra sensory perception
The general question here is whether the so called "normal" and "beyond normal" experiences are
so sharply separated and whether they do not constitute a continuity of reality. Other non-local
phenomena in this context, are called the PSI phenomena (see Fig. 24) such as clairvoyance,
telepathy, remote viewing and psychokinetic. These phenomena could also be related an underlying
non-local information field because they concern influences at a distance or messages from the
future, experienced by people. The central question is how for the necessary information for these
phenomena can reach the brain and how these extra-sensory communication / perception occur
from a mechanistic point of view.
It is important to note that much of PSI / ESP research in this field is carried out at a scrupulously
accurate manner, to exclude any form of statistical bias and misinterpretation. Yet, this research is
often focused on the direct detection of paranormal phenomena and less on the underlying physical
mechanisms of information transfer. The latter is of great importance for future investigation,
because it may provide answers to study the well-known evading aspects at sequential PSI
observations, as well how the signal strength of ESP experiences could be improved. Both aspects
could be related to the inbuilt filters in our brain that should protect us against too much disturbing
information (see Jahn and Dunne, 2007, Radin, 1996, 2006)
6. The significance of individual life in a fine-tuned Universe
The origin of life, and also the appearance of man appears to be due to fine-tuned construction: even
tiny deviation in each of the 25 fixed constants in the laws of nature, would have been fatal for the
emergence of biological life (Ross, 1989, Fig. 34). This picture is also true if one includes the
macro parameters such as the distance from the planet Earth to its sun (determining density of light,
free energy for life and temperature), the influence of the moon (influencing life cycles) and the
place of our solar system in its galaxy (just far away from a huge big black hole in the center!).
These conditions in our Universe provided that intelligent life was brought forth and that the
Universe finally created its own observers: us humans! This consideration is called the anthropic
principle: man formulated the laws of nature thereby unveiled the underlying processes of
biological evolution. In fact one could say that intelligence is an essential part of a universal
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program for the processing of information. Universal consciousness can therefore be seen as the
program on which our Universe is running (Greene, 2011, Tipler, 1996, Vidal, 2012, Wolf,
1996,1999, 2006, Meijer, 2012).
Information may have already existed at or during the "Big Bang". Recent cosmology indeed
indicates an initial scalar field exhibiting acoustic waves and fluctuation in a quantum vacuum, a
process in which energy, matter and antimatter were created. Yet, the start of the universe did not
really look like an explosion, but was, according to current cosmology, a highly fine-tuned
expansion process. Even small deviations in the particular expansion rate would have made the
creation of life impossible! For example, the formation of carbon from helium, a prerequisite for
life, would not have occurred. Again, this gives the impression of well-defined start-information,
already at the start of our Universe (Ross, 1989, Meijer, 2012).
Fig. 25: The Anthropic Principle: micro- and macro- conditions seem fine tuned to the creation of life in our
Universe
The logical question is: where did the information about the natural constants and the required
expansion rate constants come from and how could a solar system with a structure exactly as that of
ours be formed? (Fig.25). Some argue that millions of other universes exist (the multi-verse theory)
and that perhaps only in our universe conditions were such that life could emerge. However, there is
still no single piece of evidence for a multi-verse. Another hypothesis is that the constants of nature
were not always constant but that they have been gradually converged to the values needed for the
origin of life. In the aforementioned 4-dimensional domain, with all time layed out, life can even be
a product of “backward causation” of future events on the primary conditions of the big bang. The
information on advanced intelligent life in that domain could have had a time- reversed influence on
the gradual molding of these constants (thus the necessary information came from our own future).
A third hypothesis is that the information came from a previous version of our own universe, in
which, in one way or another compressed information was used for the birth process: the process of
time and history of the universe is then interpreted as circular (Gott, 1997, Penrose, 2012,
Steinhardt, 2008).
What has this supposed architecture of reality to do with immortality? It is evident that our bodies
are composed of atoms/ elementary particles that were formed 13.5 million years ago, we are,
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indeed, quite old… At the end of our material existence, thus following our personal death, these
building blocks stay manifest. Our organism may become decomposed or burned entirely, yet all of
its atoms are retained. None of these building blocks become lost, they rather may reappear in other
forms (that is in oxidized forms or becoming integrated in other organisms) or simply circulate in
the atmosphere, but the atoms are still there. One could say that the specific atoms that form our
body only become distributed over a larger area of our world, while gravity prevents diffusion away
from our planet. Yet, it is clear that their functional organization of these building blocks, that is
required for life, is completely lost.
But is this also true for the personal wave information, that is the non-material aspect of these
atoms/elementary particles. In other words, is this information destroyed? Some quantum physics
claim that information cannot be lost (the law of conservation of information) and that due to
entanglement of the wave type of these building blocks, the personal structure and functional
organization of individual life will survive bodily death (see the references of Wolf and Hameroff
and Chopra). As the consequence of the persistent storage of this information in the universal
quantum field, together with the total imprint of our personal experiences (our complete biography)
in this domain, the personal profile would be retained and would also be available for resurrection
(Tipler, 1996, Hameroff and Chopra, 2013) and, in principle, for reincarnation.
Citing the latter paper: “Recently two clinical studies used processed EEG brain monitors at the
time of death in terminally ill or severely brain-damaged patients from whom support was
withdrawn, allowing the patients to die peacefully. In both sets of patients, measurable EEG brain
activity dwindled as blood pressure dropped and, eventually the heart stopped beating. But then, in
each patient, there was an abrupt burst of brain activity lasting about a minute or more which
correlated with gamma synchrony EEG, the most reliable marker of conscious awareness. Then,
just as abruptly, the activity ceased. Because these patients died, we can’t know if they had NDE or
OOB experiences, or if the activity actually marked the soul leaving the body – ‘giving up the
ghost’. But regardless, the mystery is how the energy-depleted brain could muster synchronous
neuronal EEG activity – whatever it was. One possible answer is that consciousness and gamma
synchrony involve very low energy quantum entanglements which persist while other brain
functions
have
run
out
of
fuel.
Could consciousness exist outside the body after death? The particular authors believe it can:
“According to the Orch OR consciousness model, under normal conditions in an intact, healthy
brain, consciousness occurs as frames or snapshots extending through multiple spatiotemporal
levels from networks to neurons to microtubules to quantum forces (see also Meijer and Korf,
2013), down to and including Planck scale geometry. When the blood stops flowing and metabolic
energy can no longer drive microtubule quantum coherence, quantum information relating to the
subject’s conscious experience and memory isn’t necessarily lost or destroyed, but may dissipate to
the universe at large, remaining entangled as a unified soul-like entity grounded in Planck scale
geometry. If the body is resuscitated, the quantum information can return, and the subject may
report an NDE or OOB experience. If the body is not resuscitated and the patient dies, the entangled
quantum information constituting the subject’s consciousness and memory may persist in spacetime
geometry, perhaps entering an embryo in the context of reincarnation. Could the universe – empty
spacetime geometry – conceivably host consciousness on the loose? There is ample energy in the
form of zero point fluctuations, so the question is whether information can be registered in the
nothingness of spacetime, and transcend from Planck scale to biological scale”. Many will see this
daring hypothesis as an empty speculation or, at best, an understandable illusion, but for others it
will provide wide perspectives for potential answers to an ancient quest of mankind, regarding
individual survival and the reality of afterlife (Carter, 2012)
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7. The distant future: death and rebirth of the Universe
Transhumanists (see internet link) look into the far future, beyond the current limits of our
organisms, and especially to the technological potentials to drastically curtail the limitations of the
human body. Some physicists like Frank Tipler and Ray Kurzweil, project that our "mind children",
as very advanced, hybrid, (cyborg) machines, will ultimately travel to the boundaries of the
universe, not restricted by the current limitations of the human body, and will eventually collect all
the information about the universe and its total past history. Of note: the distances to other solar
systems, let alone to other galaxies, are so immense that our human body, even if its lifespan might
be stretched a thousand times, could never realize such extremely long journey. But intelligent
human-related machines, that can repair and reproduce themselves, would be able to do so,
provided that sufficient energy is available. As long as the universe does not die in a heating process
(and this is estimated to occur only over billions of years), the universe will be gradually populated,
and will finally become saturated with information (see Tipler, 1996 and Fig 37, Kurzweil, 2005,
and epoch 6, in Fig. 26].
In this trans-humanist concepts, ultimately, a giant omniscience (quantum) computer, that contains
a complete "database" of the past history of the universe may, according to Tipler, collect all the
information about the history of our universe. Our successors in the far future will, like us, be
curious about their origin, but their excavations will, in this case, not take place in a soil archive, but
in a huge computer database (Lloyd, 2006, Bostrom, 2003). Because all the information necessary
will be available at that time, one will be able to submit the total history of the universe to a perfect
simulation. Through unimaginably advanced technology, this simulations can be performed with
such high a quality that they will be indistinguishable from real. Such a perfect imagination was
called, by the above-mentioned scientists, an “emanation” and is supposed to occur at the, so called,
Omega point, as was earlier postulated by Teillard de Jardin (Intenet link, see also Fig.26 and 27).
Prof. Frank Tipler, 1996, a well-known American mathematician, but also a typical product of
American-Christian progress thinking, speculates that such an event may represent the Day of
Resurrection! We will all, according to this theory, experience this new life immediately after our
death, since after death our kind of time no longer exists. We all will return as individuals with our
own characteristics and live in our own (perfectly simulated) environment.... (Tipler, 1996).
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Fig. 26: The sequential epochs in the evolution of our universe, also depicting the very far future of a
"living" Universe (see black box), in a cyclic time model (top left) in which the universe takes care of its own
reproduction (after Kurzweil,2005)
However physics foretells that our world will not be everlasting…This is because our Universe is
finally doomed to a heat death (by final contraction of the Universe) or destined for a cold death (by
further expansion of the Universe). Consequently, due to the implicit destruction of the
abovementioned omnipotent computer, even the resurrected beings in their simulated paradise, will
not enjoy eternal life and thus another type of resurrection or recreation is needed (Vidal, 2012).
Only a programmed transfer of the total, condensed, information of the dying universe into an
adjacent new “baby universe” may enable such a recreation process. It is assumed in this theory that
our descendents and/or other advanced forms of intelligence will master the physics of black holes
or wormholes, seen as giant portals to other universes. These giant cosmological structure could be
manipulated to pass the required information as a recipe for the birth of a new version of our
universe (an engineered Big Bang)! Thus our successors, in the far future, may give a new start to
our universe in a kind of circular evolutionary process (Gott, 1997, Steinhardt, 2008, Penrose, 2012,
Vidal, 2012).
The projections of Gott, Penrose, Steinhart and many other scientist that have theorized on cyclic
models of the Universe, can also be interpreted to mean that our own reconstructed Big Bang, that
is often seen as the real start of the present cosmos, was rather a reflection of information transfer
from a previous version of our Universe... (see Fig. 27). However, will each cosmic cycle
encompass identical information, so that all of us will be reproduced, or will each rebirth also
contain novel information and innovations, leading to ever growing complexity and intelligence of
cosmic life?
…. The Cycle of Life:
Rebirth of our Universe
…
Fig. 27: Death and birth of the Universe: information is compressed by an advanced civilization as a recipe
for the next universe. This transmission process may lead to a new version of our universe via a mastered
technology of engineered black holes or wormholes (right below).
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8. Final summary
The desire for immortality that, like a red thread runs through ancient myths, religions and wisdom
traditions, in this manner obtains a cosmological outlet in a new human evolution.
Represent these thoughts just a curious kind of "Science Fiction" or do they perhaps relate to a
veiled, reality? Anyway, current science often draws its inspiration from such images of the future,
and at the same time these projections may serve to shape the future of mankind...
In his thesis on the beginning and end of our Universe, Vidal (2012) stated: “But how can we
imagine to seriously care for such an issue as cosmological immortality? We can summarize five
steps towards it. The first is to realize that your individual death is normal and inevitable in the long
term. The second is to develop psychologically, and fulfill all your needs to grow the hierarchy of
needs up to the need of self-transcendence. You then surpass yourself to become compassionate and
identify with the process of cosmic evolution. Even if you accept individual death, you still refuse
death as a whole, namely the idea that nothing would continue to evolve after the predictable death
of your body, society, species, Sun, galaxy and universe. You then set the immortality of the
evolutionary process as a goal”.
Immortality indeed represents a truly a multi-layered concept. Those who are interested in the
various aspects of immortality, see the books of Van Bergen, Chown, Pickover,Weiner, and Cave.
Interested readers may share some frequently asked questions: are humans intrinsically immortal
(see references of Carter, Phipps, Peake, Wolf, Hameroff, Van Lommel, Forberg, Braude and
Fontana), or: will we, ultimately, become physically immortal either by advanced medical
technology (see De Grey, Post, Shapin) or by becoming some modality of cyborg (Tipler,
Greenfield, Kaku, Moravic, Kurzweil).
Alternatively, some claim that there is a perspective for immortality for all of us: through rebirth
and eternal cycling of our Universe (Gott, Penrose, Steinhart, Vidal). Yet, all of these concepts can
be viewed upon as a process of conservation of information.
Acknowledgement: I am indebted to Drs. Elizabeth Waltheer for checking the language and Prof.
Jan Engberts for critically reading and valuable comments on the manuscript.
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Websites/Articles on Life extension and Immortality (general):
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Ageing: Wikipedia: http://en.wikipedia.org/wiki/Ageing
Anti-Ageing medicine: http://en.wikipedia.org/wiki/American_Academy_of_AntiAging_Medicine
Ben Best, 2012. Life Extension Writings: http://benbest.com/lifeext/lifeext.html
Biological Immortality: Wikipedia: http://en.wikipedia.org/wiki/Biological_immortality
Cryonics: Wikipedia: http://en.wikipedia.org/wiki/Cryonics
Engineered negligible senescence: Wikipedia:
http://en.wikipedia.org/wiki/Negligible_senescence
Epic of Gilgamesh: Wikipedia: http://en.wikipedia.org/wiki/Epic_of_Gilgamesh
Ian Stevenson: http://en.wikipedia.org/wiki/Ian_Stevenson
Immortality: Wikipedia: http://en.wikipedia.org/wiki/Immortality
Information Universe. http://www.sintropia.it/english/2012-eng-1-1.pdf
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Life extension: Wikipedia: http://en.wikipedia.org/wiki/Life_extension
List of long living organisms: Wikipedia: http://en.wikipedia.org/wiki/List_of_longliving_organisms
Maximum lifespan: Wikipedia: http://en.wikipedia.org/wiki/Maximum_life_span
Rejuvenation: Wikipedia: http://en.wikipedia.org/wiki/Rejuvenation_(aging)
Reincarnation: http://en.wikipedia.org/wiki/Ian_Stevenson
Second Life: Wikipedia: http://en.wikipedia.org/wiki/Second_Life
Strategies for Engineered negligible senescence: Wikipedia
https://en.wikipedia.org/wiki/Strategies_for_Engineered_Negligible_Senescence
Teillard de Jardin: http://en.wikipedia.org/wiki/Pierre_Teilhard_de_Chardin
Telomerase: Wikipedia: http://en.wikipedia.org/wiki/Telomerase
Telomere: Wikipedia: http://en.wikipedia.org/wiki/Telomere
Magazines/Institutes
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Life extension magazine: http://www.lef.org/magazine/index.htm
Fight aging: http://www.fightaging.org/articles/
Programmed aging: http://www.programmed-aging.org/
Immortality institute: http://www.longecity.org/
Mehthuselah Foundation: http://www.methuselahfoundation.org/
American Academy of Anti- Aging Medicines: http://www.a4m.com/
Sens research foundation: http://www.sens.org/research
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