2014-2015 Annual Report - School of Sciences and Mathematics

Transcription

ANNUAL REPORT
2014-2015
School of Sciences and Mathematics Annual Report 2014‐2015 Executive Summary The 2014 – 2015 academic year was a very successful one for the School of Sciences and Mathematics (SSM). Our faculty continued their stellar record of publication and securing extramural funding, and we were able to significantly advance several capital projects. In addition, the number of majors in SSM remained very high and we continued to provide research experiences for a significant number of our students. We welcomed four new faculty members to our ranks. These individuals and their colleagues published 187 papers in peer‐reviewed scientific journals, many with undergraduate co‐authors. Faculty also secured $6.4M in new extramural grant awards to go with the $24.8M of continuing awards. During the 2013‐14 AY, ground was broken for two 3,000 sq. ft. field stations at Dixie Plantation, with construction slated for completion in Fall 2014. These stations were ultimately competed in June 2015, and will begin to serve students for the Fall 2015 semester. The 2014‐2015 academic year, marked the first year of residence of Computer Science faculty, as well as some Biology and Physics faculty, in Harbor Walk. In addition, nine Biology faculty had offices and/or research space at SCRA, and some biology instruction occurred at MUSC. In general, the displacement of a large number of students to Harbor Walk went very smoothly. Temporary astronomy viewing space was secured on the roof of one of the College’s garages. The SSM dean’s office expended tremendous effort this year to secure a contract for completion of the Rita Hollings Science Center renovation, with no success to date. We continue to see expanding interest in STEM programs and remained a major producer of STEM graduates in South Carolina. A prominent feature of SSM is the extent to which our students obtain real‐world, hands‐on experience in research laboratories, internships, and field experiences. These experiences are critical to preparing students for graduate and professional study, as well as for entering the work force. STEM fields continue to dominate lists of the most lucrative employment fields. A recent article in Forbes Magazine lists the Top Degrees for Getting Hired in 2015 based on a study by the National Association of Colleges and Employers (NACE). It revealed which majors college career placement offices are looking to place with employers. The article discusses three areas with specific degrees most in demand. Computer science was ranked the third top Bachelor’s degree in demand; computer science, accounting, and information sciences & systems were among the top 10 Master’s Degrees and ; physics, computer science, math/statistics, and chemistry were among the top 10 Doctorate degrees. To note: all 10 top Doctorate Degrees in Demand were in STEM fields. SSM is committed to preparing our students for education and careers beyond our borders. 1 School of Sciences and Mathematics Annual Report 2014‐2015 SCHOOL Mission Statement and Goals Our mission is to integrate discovery, innovation and education in order to serve our students, our state and our nation. The principal responsibility of the School of Sciences and Mathematics is to provide the science and mathematics courses for all students at the College, and, concomitantly, to equip students who major in sciences and/or mathematics with the knowledge and skills to pursue careers in a wide variety of fields, including, science, engineering, medicine and allied health, law, social services, and journalism. The school's graduate programs have been carefully selected both to complement the undergraduate programs in areas of significant national strength and to meet the intellectual, professional and economic needs of the region and the state. Our vision and our mission are founded on our core values ‐‐ those principles that define and guide the way in which we achieve our mission. The School of Sciences and Mathematics reflects the values of a public liberal arts and sciences university. We value: 
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Students as individuals Our colleagues and peers as teachers and scholars Commitment to responsible and ethical practices in research and pedagogy Inquiry and intellectual curiosity Meaningful engagement with the community, region and state Collaborative effort and lifelong learning Diversity and dialogue Assessment and accountability as key tools to drive continuous improvement Our goals in science are to help assure that all graduates of the College of Charleston: 1. Can demonstrate understanding of some of the fundamental scientific concepts and theories about the natural world; 2. Acquire a knowledge of the evidence, ideas, and models that scientists use to make judgments about the natural world; 3. Acquire a knowledge about science and technology as they shape contemporary experience and values, and demonstrate an appreciation of the historical and contemporary impact of science on daily life; 4. Develop the skills of logical and critical thinking necessary to explore how the natural world works; 5. Can demonstrate an appreciation and understanding of the scientific method of inquiry; 2 School of Sciences and Mathematics Annual Report 2014‐2015 6. Understand that scientific knowledge is based on the outcomes of testing of hypotheses and theories that are under constant scrutiny and subject to revision based on new observations, and such knowledge is not just a collection of facts; 7. Can demonstrate an ability to distinguish between science and technology and appreciate the capabilities and limitations of both; Our goals in mathematics are to help assure that all graduates: 1. Develop an appreciation for the practical value of mathematics in the modern world; 2. Can interpret mathematical models such as formulas, graphs, tables, and schemata, draw inferences and make decisions from them, and communicate these conclusions verbally; 3. Can organize information, recognize patterns and relationships, and represent them mathematically; 4. Can use mathematical, analytical, and statistical methods to solve problems and recognize limits of the methods; 5. Can estimate and check answers to mathematical problems in order to determine whether an answer is reasonable, and critically appraise numerical information; 6. Can apply mathematical methods in the context of other disciplines, and reason logically and recognize where conclusions can be drawn from a set of hypotheses. For Sciences and Mathematics majors, the School has the responsibility to lead students toward acquiring a depth of knowledge and competence in their respective disciplines. In particular, science and mathematics graduates should have: 1. The ability to recount and explain the basic facts and postulates of the discipline and to use these in the solution of problems with which the discipline concerns itself; 2. Proficiency in the use of the techniques and tools of the discipline; 3. An awareness of the resources of the discipline and the ability to seek out and assimilate knowledge that has not been a part of the classroom experience; 4. The ability to relate knowledge in the discipline to other disciplines. A key element of our mission is accountability, which includes regular assessments of the effectiveness of School of Sciences and Math programs. Departments must be alert to opportunities to measure their programs against objective indicators of programmatic quality, such as accreditation reviews and external program evaluations. The School of Sciences and Mathematics recognizes that a college education is not merely an independent activity that follows high school but is part of a greater educational experience that begins in kindergarten. Academic departments are sensitive to their obligation to promote education at all levels. Consequently, faculty engagement in pre‐college activities with students and teachers is regarded as an important part of the mission of the school. A central element of the mission of the School of Sciences and Mathematics is to sustain the involvement of its faculty in research and scholarship. Scholarly activities of the faculty not only are essential for maintaining the intellectual environment that characterizes an excellent institution of higher learning, but they support the mission of the College by providing students a community in which to engage in original inquiry and creative expression. Faculty members are urged to guide students in research activities whenever possible. All undergraduate programs in the School of Sciences and 3 School of Sciences and Mathematics Annual Report 2014‐2015 Mathematics use independent study and student‐faculty research as important methods for developing intellectual independence and creativity as well as for teaching appreciation and understanding of sciences and mathematics. Research is central to the goal of leading students to connect their coursework with the techniques and applications of their disciplines. Strategies and tactics in the College’s strategic plan your department would place as highest priorities Strategy 1: Enhance the Undergraduate Academic Core 1.1 Provide each student a personalized experience that integrates classroom learning with at least two of the following: research and creative activities, civic engagement, study away, internships, and peer education. The School of Sciences and Mathematics believes that undergraduate research is essential to learning. Undergraduate majors receive a highly personalized experience when mentored by our faculty in current, relevant, private, state and federally funded research. This work aids a student’s comprehension of their field and better prepares them for graduate programs and industry work. Research grant funds provide students with stipends necessary to forgo jobs in unrelated areas so they can stay focused on their field and often travel to conferences where they present their findings. The Department of Mathematics furthered the personalization of education with the implementation of ALEKS. This intuitive math placement exam, now mandatory for all incoming undergraduates, insures that math skills are properly assessed so students can properly design their course of study and increase their chances of success in their major and at the College. The Department of Chemistry & Biochemistry uses LearnSmartPrep as an on‐line, self‐paced tool to help students assess their preparedness to take introductory chemistry and to remediate any deficiencies at the start of the semester. The School of Sciences and Mathematics continued to play a strong role in the College’s study abroad programs. Faculty led students to Trujillo, Germany, Panama, Indonesia, Ecuador and the Galapagos Islands, and the U.S. British Virgin Islands. Exchange programs with Xiamen University in China and the University of Tartu in Estonia continue to grow. The Department of Mathematics is in negotiations for an exchange program with the University of São Paulo in Brazil. Faculty members from the Department of Geology traveled to South Africa to begin planning for study abroad in Summer 2016. Faculty and students of the Department of Geology and Environmental Geosciences routinely travels for field research. This year 29 geology students completed their annual Maymester field studies trip which was comprised of three weeks of mapping geological sites in Utah, Arizona, Nevada, and California. Sites included Yosemite National Park, Zion National Park, Cathedral Gorge, and North Rim, Grand Canyon. Fourteen BEAMS seafloor mapping students took a four‐day cruise off the coast of Charleston led by Drs. Leslie Sautter and Scott Harris. Six students experienced a 10 day field course at the Gerace Research Centre in the Bahamas during the December holiday break. 1.2 Enhance undergraduate academic programs that are strongly linked to the history, traditions, culture, and environment of Charleston and the Lowcountry, such as a new undergraduate majors in African‐American Studies and sustainability. Many of our programs take full advantage of our regional setting. The College of Charleston was recently listed among the Top 10 Marine Biology programs in the United States. The Grice Marine Laboratory on James Island offers the unique opportunity to collaborate and work with a large, diverse group of 4 School of Sciences and Mathematics Annual Report 2014‐2015 dedicated scientists at the Fort Johnson Marine Science Center. Our coastal South Carolina location provides an excellent setting in which to study and explore a variety of marine ecosystems. Students in graduate and undergraduate programs in Environmental Studies, Biology, and Geology also take advantage of our coastal location and partners at Fort Johnson. Locations such as Dixie Plantation, Folly and Edisto Beach, and Frances Marion National Forest provide outdoor classrooms for natural science labs. Students can study marine and animal habitats, water systems, and botany in natural settings. Our climate allows for extended access to these areas. This summer construction of two field stations at Dixie Plantation was completed. These low carbon footprint, self‐sustaining buildings will provide classrooms right in the heart of this diverse ecosystem. The field stations will house classes offered in biology, geology, astronomy, archaeology and environmental studies beginning Fall 2015. 1:3 Develop academic programs at the College of Charleston North Campus to offer lifelong learning courses and programs to serve the needs of returning adult learners or non‐degree students. Classes required for the M.S. in Computer & Information Systems have been taught at the Lowcountry Graduate Center. The School continues to explore strategies to expand course offerings on this campus. Computer Science remains actively involved in the new Bachelor of Professional Studies by supporting a concentration in Information Systems. Seven elective courses in areas such as Communications Technology & the Internet, Website Design, Database Security, and Ethics in Information Systems are offered. 1:4 Strengthen the Honors College through dedicated faculty for innovative curriculum Faculty members in all six departments of the School contribute to Honors curriculum. The departments of Biology, Chemistry, Geology, Mathematics, and Physics have dedicated Honors Intro Sections. Elizabeth Meyer‐Bernstein, Associate Professor of Biology, was named Associate Dean of the Honors College in summer 2014. 1:9 Increase significantly the numbers of and enrollments in interdisciplinary courses and programs Our faculty continues to contribute heavily to the First‐Year Learning Communities to foster interdisciplinary relationships between departments for unique learning experiences. Chris Korey, Associate Professor of Biology, serves as Director of the First‐Year Experience. The School houses two interdisciplinary programs that bridge the School of Sciences and Mathematics with the School of Humanities and Social Sciences. Both the graduate and undergraduate programs in environmental studies as well as the neuroscience minor continue to see an increase in enrollments. SSM has added 3 more roster faculty to the Neuroscience minor. With the expansion of the faculty we continue to see a steady increase in the number of graduating minors. There are now over 70 declared minors overall. The program has a strong relationship with the Neuroscience Department and Neuroscience Institute at MUSC which attracts students interested in pursuing research opportunities with MUSC faculty. It is unclear what the future holds for an Interdisciplinary Major in Neuroscience at the College. Popularity of the current minor suggests heavy enrollment in a major, but this would potentially further strain already taxed resources in both Biology and Psychology. The Neuroscience Steering Committee 5 School of Sciences and Mathematics Annual Report 2014‐2015 will continue discussions but are generally agreed that a major would not be instituted until the renovations of the Rita Hollings Science Center are complete. Assessment of the environmental studies minor showed that course offerings in the area of humanities and social sciences are currently inadequate, particularly in the area of political science. Like Neuroscience, faculty hope to develop BS/BA tracks in Environmental Studies. Strategy 2: Develop nationally recognized graduate programs 2:1 Emphasize the acquisition of research and teaching grants to develop interdisciplinary, international and innovative programs that capitalize on our unique location and capabilities. Faculty in the marine biology program continued their success in securing extramural research and teaching grants. Faculty in this discipline secured $1.89M which includes a $575K MRI Acquisition grant from the National Science Foundation. Funded research interests include: 1. Marine genomics 2. Detection of an invasive parasite of American eels 3. Modeling and analysis of the Gulf ecosystem 4. Analysis of jaws and backbones of sharks for inclusion on the vertebrate tree of life 2:2 Enhance graduate programs in marine biology, environmental studies, historic preservation, and arts management to achieve national recognition. Our Graduate Program in Marine Biology continues to be highly competitive and nationally ranked. The program attracts applicants from all over the country. Fall 2015 incoming students hail from institutions such as: Vanderbilt; Rutgers; Georgia State; Florida State; University of Kentucky; and Davidson. The Masters of Environmental Studies (MES) program enrollment decreased slightly with 97 students actively enrolled and/or working on internships and thesis projects during the last year compared to the 113 on record for 2013‐2014. A total of 21 new students enrolled in the MES program in the 2014‐2015 academic year. Out‐of‐state students represented 39% of this total. The ability of the MES program to provide students with a comprehensive background in both policy and science remains an attractive feature for prospective students. However, resources committed to this program are low. The program employs one full‐time Program Coordinator who oversees administrative duties, logistics, and advising. Dr. Tim Callahan, a professor of Geology, serves as program director. Currently there are no roster faculty members designated fully to this discipline. Classes are taught by adjuncts and faculty borrowed from other departments. The MES Program has a prominent position in the revised strategic and master plans for the College of Charleston. The MES program and its Peace Corps Master’s International option and Dual‐Degree Public Administration/Environmental Studies program have a solid reputation and strong interest from prospective students, thus producing greater interest in University of Charleston graduate studies. However, the current structure of the program is not resilient. MES needs to increase the number of full‐time equivalent faculty in order to meet specific areas of need in sociology, chemistry, and education. 6 School of Sciences and Mathematics Annual Report 2014‐2015 Strategy 4: Recruit, enroll, and retain an academically distinguished, well‐prepared and diverse student body. 4:4 Increase the amount of merit‐based and need‐based scholarship funding largely funded through private resources. In the academic year 2014‐2015, the School of Sciences and Mathematics awarded approximately $195,500 in scholarships. These funds came from both private donors and public sources. Fourteen incoming freshman intending to major in computer science were awarded recurring scholarships in amounts varying from $2500 ‐ $5000 per year. These funds were made possible by a special appropriation from the State of South Carolina. The appropriation was provided to support the College’s dedication to helping grow the Charleston a recognized digital hub by attracting the brightest and best to the area. Four of the fourteen recipients were female, mirroring the female population within the department which is 24% of the CSCI student body. Programs like Women in Computing have helped achieve a better gender balance in computer science. Four students continue to be funded by a grant from the Clemson University Center for Workforce Development (CUCWD). Preference for this award was given to first generation college students from traditionally disadvantaged backgrounds and/or from underrepresented groups. All four recipients continue to maintain a 3.0 gpa to meet eligibility for renewal. In an effort to retain minority students the chemistry department offered CHEM 103, a pre‐CHEM 111 course for twelve students who participated in the SCAMP/SPECTRA Summer Bridge program. After two summer sessions, these students had an average GPA of 3.06. The average Fall CHEM 111 grade is 2.7 versus the average grade for underrepresented minority students of 1.89. This fiscal year Boeing continued its support by providing four scholarships for students interested in pursuing careers in the aerospace industry. The Dr. Stephanie Dellis Scholarship in Biology matured and was able to provide funds for one upperclass, biology major whose studies focus on molecular biology. BiblioLabs continued their commitment to pay full tuition for two in‐state computer science majors. The W. Frank Kinard endowment continues to grow and will soon provide funding for scholarships in the areas of chemistry and biochemistry. Other endowed scholarship funds continue to grow providing more funds to award each year. Strategy 7: Provide up‐to‐date facilities and infrastructure to enhance academic, co‐curricular, and extracurricular programs. 7:1 Build, renovate, and maintain classrooms, laboratories, and studios that allow for a variety of class sizes and teaching and learning styles. The Rita Hollings Science Center was emptied in May 2014. The building was abated and the space has been prepared for construction. Physicians Auditorium is being demolished in late summer 2015. Departments normally housed in RHSC are temporarily located at Harbor Walk, the School of Sciences and Mathematics Building, SCRA, MUSC, and JC Long. The Department of Computer Science has become quite comfortable in its newly acquired offices at Harbor Walk. This location allows faculty and students access to the fast growing Charleston Digital Corridor. 7 School of Sciences and Mathematics Annual Report 2014‐2015 This summer, two new field stations opened on Dixie Plantation. They will begin housing classes, labs and support research efforts in Fall 2015. In future years, the School hopes to move forward on a new building for the Grice Marine Lab at Fort Johnson. Plans are complete and most funding has been secured for this project. FACULTY WORKLOAD Enrollments 2014‐2015 Department Biology Chemistry and Biochemistry BIOL TOTAL CHEM Fall 2014 Spring 2015 G U 158
4371
158
4371
0
1989
G 148 148 0 U 4740
4740
2126
Computer Science Geology and Environmental Geosciences TOTAL CSCI CSIS CITA DATA TOTAL GEOL 0 0 20 0 0 20 0 2126
1007
0
67
51
1125
1921
0
0
24
0
0
24
0
1989
1179
0
50
52
1281
2171
Mathematics Physics and Astronomy TOTAL MATH TOTAL ASTR 0 54 54 0 1921
3840
3840
637
0
43
43
0
2171
2905
2905
627
School Total PHYS TOTAL 0 0 222 904
1541
15,290
0
0
225
918
1545
14,262
Average Undergraduate Class Size Department Biology Chemistry and Biochemistry Subject CHEM 24.0
Computer Science CSCI 23.2
BIOL Average Class Size 26.0
8 School of Sciences and Mathematics Annual Report 2014‐2015 Geology and Environmental Geosciences Mathematics Physics CITA DATA 19.1
24.0
GEOL MATH ASTR PHYS 27.1
33.2
27.5
21.2
26.8
SCHOOL AVG
Declared Majors Major Biology Marine Biology Biochemistry Chemistry Computer & Info Sciences Computer Info Systems Computer Science Computing in the Arts Data Science Environmental Studies Environ Studies/Dual Pro Geology Mathematics Astronomy Astrophysics Physics School Total U
749
165
93
104
25
59
264
64
34
G
49
55
20
120
73
3
32
67
1854
18
167
Fall enrollments were up in most departments. We noticed a slight dip in enrollments in BIOL and PHYS Intro courses and suspect the recent move to Harbor Walk may be responsible. Majors from other Schools who are completing science credits may be avoiding the trip to Harbor Walk and are instead registering for Geology or Chemistry courses offered in SSMB at 202 Calhoun Street. Research‐active faculty members in the School of Sciences and Mathematics teach a 3:3 course load, unless altered by special exception. In addition to teaching regularly scheduled classes and advising declared majors, faculty pursue research grants, mentor undergraduate research assistants, participate in external STEM outreach events, contribute to graduate and special programs such as Honors and First Year Seminar as well as interdisciplinary majors and minors such as Neuroscience, Environmental Studies, Science and Math for Teachers, and serve on 9 School of Sciences and Mathematics Annual Report 2014‐2015 departmental and College‐wide committees. Instructors teach a 4:4 course load as well as participate in many of the same additional duties listed above. In order to prepare major students for upper division courses, departments prefer to place roster faculty in introductory level courses. Unfortunately, the ability to make roster faculty available for foundation courses is limited by the need for their expertise in upper level and graduate courses. In introductory lecture sections only 58% of our students across SSM see a roster faculty member as their instructor. In larger departments, such as Biology, one unintended side‐effect of these efforts, particularly when combined with support for Honors and FYE, is that junior and senior majors increasingly report difficulty finding seats in upper level major courses. The implementation of the popular Public Health major increased enrollment in Anatomy and Physiology making it increasingly difficult for Biology majors to complete this course. For more information refer to the Assessment portion of this report. Research and Professional Development This year Science and Math faculty members obtained $6.4M in newly awarded research grants and continued work on $24.8M in ongoing grants. Grants were from federal, state and private sources such as: National Science Foundation; US Fish and Wildlife Service; Medical University of South Carolina; Slocum‐Lunz Foundation; SC Department of Natural Resources; University of Southern Florida; Howard Hughes Medical Institute; National Institutes of Health (SC‐INBRE); Camille & Henry Dreyfus Foundation; American Chemical Society; NASA; NOAA; SC Sea Grant Consortium; and the Chandra Observatory at Harvard University. SSM faculty published 187 articles in peer reviewed journals and presented their research at both national and international conferences. Over 60 students were published as co‐authors and also traveled to regional and national conferences to present posters. Research interests include: 1. Environmental issues such as: climate change; degradation of pharmaceuticals in waste water and its effects on the wildlife; relationship between population growth and land‐
cover change in Charleston; health of marine organisms; nutrient cycling in Antarctica; invasive seaweeds; green chemistry and the transformation of waste products. 2. Astrophysical topics: accretion onto black holes; structure of quasars; search for exoplanets. Grants obtained for professional research can be found in Appendix A. Publications reported to the Faculty Activity System can be found in Appendix B. Special publications, conference proceedings, and patents can be found in individual department reports. Service In addition to department programs and standing committees (such as curriculum, scholarship, assessment, long range planning, and safety) many SSM faculty members provide service to College‐wide committees and external professional organizations. Some examples of these activities include: College committees: 10 School of Sciences and Mathematics Annual Report 2014‐2015 
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Pam Riggs‐Gelasco: Chair, Council of Chairs Amy Rogers: Chair, Grievance Committee Christine Moore: Director, SC Alliance for Minority Participation (SCAMP) Renee McCauley: Post‐tenure Review Committee Member Aspen Olmsted: Distance Education Steering Committee Steve Jaumé: Faculty Curriculum Committee National and regional offices within their discipline:  Lou Burnett: Associate Editor, Biological Bulletin; President, Southern Association of Marine Laboratories; President‐Elect, Society for Integrative and Comparative Biology  Robert Dillon: Treasurer, Lowcountry Phi Beta Kappa Association  Jack DiTullio: Editorial Board Member of Association of Oceanography and Limnology; NSF Proposal Review Panelist for Biological Oceanography  Melissa Hughes: Associate Editor, Behavioral Ecology and Sociobiology  Susan Morrison: Executive Board Member, Howard M. Jenkin Medical Foundation  Jim Deavor: Secretary/Treasurer, South Carolina Section American Chemical Society  Neal Tonks: Chair, South Carolina Section American Chemical Society  Renee McCauley: President/Elect/Past, ACM Special Interest Group in Computer Science Education  K. Adem Ali: Editorial Board Member, Hydrogeology & Hydrologic Engineering  Cassandra Runyon: Director, SC Space Grant Consortium  Erin Beutel: Associate Editor, Geological Society of America Bulletin  Sorinel Oprisan: Councilor for Physics and Astronomy, Division of Council on Undergraduate Research (CUR); Editor, CUR Quarterly  Ana Oprisan: President, South Atlantic Sections of the American Association of Physics Teachers Outreach School of Sciences and Mathematics faculty, staff, and students participate regularly in STEM outreach activities throughout the Lowcountry and Tri‐County area. Faculty host school groups on campus, organize public events, and visit local elementary and high schools to give presentations that inspire interest in higher learning in the STEM fields. Thanks to their efforts thousands of students in the Charleston County School District and beyond are exposed to natural and physical sciences, mathematics, and computer science each year. The Mace Brown Natural History Museum continues to be a favorite field trip for hundreds of local school children, senior groups, clubs and organizations, homeschoolers, local citizens and fossil aficionados, and tourists. The museum displays more than 3,000 fossil specimens that demonstrate how the Earth and life on Earth has changed over the past 3.45 billion years. In June 2013 Mr. Brown gifted his $1.6M collection of fossils to the School. This past year, the museum was expanded to accommodate an exhibit that displays examples of whale evolution. This new section of the museum house Cotylocara macei, the subject of a recent study by James Carew and Jonathan Geisler ’95 that dated echolocation as far back as 28 million years. Since opening in 2010, over 5000 local school children have enjoyed the museum. 11 School of Sciences and Mathematics Annual Report 2014‐2015 On February 13, 2015, the School of Sciences and Mathematics teamed up again with Athletics to provide hands‐on activities to over 2000 local school children who attended the 3rd annual STEM Education Day at TD Arena. Faculty representatives from all six department as well as staff and students were in attendance with bones, biological specimens, marine touch tanks, rock samples, chemistry experiments, robotics, and math puzzles designed to engage students one on one and excite their curiosity in the sciences and mathematics. Afterwards, students cheered on the Women’s Basketball team as they played Hofstra. This popularity of this event demonstrates the need for STEM education outreach. Planning has already begun for 2015. Last year the School began a partnership with the RiverDogs when it participated in Education Day at Joe Riley Jr. Park. In lieu of that event, the School brought STEM outreach to a Saturday evening game. Faculty and staff from the Department of Physics & Astronomy as well as faculty and students affiliated with the SC Space Grant Consortium participated in the Astronomers Without Borders, Global Star Party, hosted by the RiverDogs to celebrate the Hubble Space Telescope’s 25th Anniversary on Saturday, April 25, 2015. NASA loaned out a moon rock for the event and astronomy faculty were on hand with solar scopes so patrons could view the sun. The Lowcountry Hall of Science and Math set up an inflatable star lab for pregame outreach while physics faculty offered a table with hands‐on activities. Moon Pie donated treats as parting gifts for patrons. Christine Moore continued to facilitate Girls Day Out. The event, held on July 25, 2014 attracted 55 young women ages 12‐14 from the Tri‐County area to campus. The overnight experience is a collaborative partnership with SPAWAR Systems Center (SSC) Atlantic, the National Defense Education Program, Trident Technical College and College of Charleston. The girls and their parents learned about various STEM career opportunities, degree programs, and admissions requirements. The mission of this program is to provide participants with the opportunity to meet women working in STEM fields and to provide hands on activities that promote and encourage programs of study and careers associated with STEM. The 2015 Darwin Week was held February 7‐12, 2015 with an emphasis on teaching the controversy. As always lectures were provided by those in both the religious and scientific professions. Members of the College and Charleston communities packed venues to hear guest speakers who included: Jeremy Rutledge, Senior Minister, Circular Congregational Church; Lee Dugatkin, Professor of Biology, University of Louisville; Jon Hakkila, Professor of Physics & Astronomy, College of Charleston; John Hildebrand, Regents Professor of Neuroscience and Professor of Chemistry & Biochemistry, Entomology, and Molecular & Cellular Biology, University of Arizona in Tuscon; Emily Willoughby, writer and scientific illustrator. For the second year in a row, students from the Tricounty area participated in Piccolo Darwin Week. Lectures tailored to elementary age children were offered at venues both on and off campus and we offered tours of the Natural History Museum that documented whale evolution as well as a hands‐on simulated lab of virtual organisms. 12 School of Sciences and Mathematics Annual Report 2014‐2015 This year’s Annual Math Meet attracted 442 students from 41 schools located in South Carolina, North Carolina, and Georgia. This is actually about 100 students less than averaged over past years. One major reason for the decline was due to renovations of Physician’s Auditorium. Sottile Theatre needed to serve as the main auditorium for the event and based on its availability, the Meet was scheduled for Valentine’s Day, which coincided with a President’s Day Holiday on Monday, February 16. Given the three‐day weekend, many schools were unable to attend due to prior commitments. Once the Meet is able to move back to its regularly scheduled timeslot at the end of February, we expect attendance to increase. The College’s Math Meet started in 1978 and predates almost all other college sponsored high school mathematics competitions. It is designed to encourage students of all levels in their math studies. The Departments of Chemistry, Computer Science, and Physics also participate by offering events and demonstrations making the competition an all‐day event that advertises the College and exposes students to the broader impacts of mathematics on the sciences. The event achieved its goal of making many students feel like winners; 26 of the 41 schools that participated took home at least one award. The Lowcountry Hall of Science and Math (LHSM), the School’s educational outreach center, held the 35th Annual Lowcountry Regional Science and Engineering Fair on March 24, 2015 at TD Arena. The Fair is open to students in grades 5‐12 in Berkeley, Charleston, Colleton, Dorchester, and Georgetown counties. This year 126 students presenting 87 projects represented 15 schools including Academic Magnet High School, Porter Gaud, St. Andrews School of Math and Science, Burke Middle School, Daniel Island, and Palmetto Scholars Academy. There were 46 volunteer judges from the organizations such as College of Charleston, Boeing/AIAA, MUSC, NOAA, the Citadel, Charleston Soil & Water Conservation District, and S2TEM Centers SC. The Fair is affiliated with the Intel International Science and Engineering Fair (ISEF). Senior Division first place winner Bertrand Zhang, a twelfth grade student from Academic Magnet, represented the region at the ISEF in Pittsburgh, PA May 10‐16, 2015. Her expenses and those of her mentor were paid by the Lowcountry Science Fair and a donation from the Charleston Defense Contractors Association, a long‐time supporter of the Fair. Other corporate sponsors included Patriots Point Foundation Cold War Submarine Memorial Fund. Cynthia Hall, Director of LHSM, served on the planning committee for the 2nd Annual Charleston STEM Fest, hosted by Lowcountry STEM Collaborative. The 2015 STEM Fest took place on February 7, 2014. Faculty from all six academic departments as well as student organizations participated by manning hands‐on activities and performing experiments for guests. Over 7,500 people attending the festival held at Brittlebank Park. STEM Collaborative partners include Bosch, The Citadel, Boeing, Google, InterTech Group, The South Carolina Coalition for Mathematics & Science, Charleston Southern University, and STEMPremier. SSM plans to participate in the third festival scheduled for February 6, 2016. CORAL (Community Outreach Research and Learning) Program at Grice Marine Lab, led by Pete Meier, exposes students of all ages to the local marine environment through regular on and off campus programs. This year CORAL conducted 51 events that served approximately 13 School of Sciences and Mathematics Annual Report 2014‐2015 3800 school children, which is triple the amount than in the previous year. In addition, CORAL regularly participates in group STEM outreach events such as STEM Day at TD Arena, STEM Fest, Earth Fair in North Charleston, and the Marion Square Green Fair which interface with thousands of students and adults in the Lowcountry. CORAL touch tanks have become a highlight of these events. On November 3, 2014 Wendy Cory, Department of Chemistry and Biochemistry, worked with the Literacy Outreach Initiative (LOI) now Honors Engaged to host a day of science activities for 100 area fifth graders from Title I schools based on the book The Frog Scientist, a children’s book about SC native and world‐renowned herpetologist Dr. Tyrone Hayes. On December 11, 2014 100 sixth graders from Title I schools experienced the same type of program, this time based on the book Tracking Trash, a children’s book about trash found in the ocean, especially the Great Pacific Garbage Patch. Both events were funded by a grant from the National Science Foundation. Students from Mitchell Elementary made their annual visit to the School in January 2015 to experience hands‐on science lessons. This event, now in its seventh year, provided learning opportunities in biology, chemistry, physics, and geology for over 200 students, grades 3‐6. The 2‐day field trip gave underrepresented students an intimate connection with the scientific process by working in fully equipped, state‐of‐the‐art laboratories, with real scientists. Astronomy Observatory Open Houses are currently unavailable due to the ongoing renovations of the Rita Hollings Science Center (RHSC). The Astronomy Deck has been temporarily moved to the top of the St. Philips Parking Garage. Although this location is suitable for labs, it was decided it was not in the best interest of the safety and security of community guests to hold viewings in the garage. Public open houses will resume once the astronomy deck at RHSC is complete. Faculty members regularly participate in outreach activities hosted by local and regional schools, career days, and science nights. Select educational outreach activities include:  Anthony Harold: Adopt‐a‐Highway participant  Eric McElroy: Guest speaker at Chicora Elementary Child Development Class  Courtney Murren: Exhibitor, James Island Elementary STEM night  Gavin Naylor: Guest speaker, Milstein Lecture Series ~5000 NYC middle school children  Ana Zimmerman: Organizer, bone marrow donor registry drive; hands‐on DNA workshop at SC Jr. Academy of Sciences  Marcello Forconi: Chemistry demonstration for Kindergarten class at Orange Grove Elementary Charter School  Amy Rogers: As faculty advisor for the Alpha Chi Epsilon chemistry fraternity, organized science experiments at Stiles Point Elementary and STEM night at Summerville Elementary  Wendy Cory: Led a week of STEAM Camp at the School of the Arts for elementary students from the Charleston County School District 14 School of Sciences and Mathematics Annual Report 2014‐2015 
Drs. Sorinel and Ana Oprisan: Organized four different workshops for middle and high school teachers from Berkeley, Charleston, and Dorchester counties. ADDITIONAL INSTRUCTIONAL CONTRIBUTIONS Contributions to the Honors College The Schools commitment to the Honors College continues to grow. In 2014‐2015 SSM faculty offered a total of 56 credit hours to the HONS curriculum. Offerings included:  HONS 115: Honors Calculus  HONS 151/151L: Honors Biology I/Lab  HONS 152/152L: Honors Biology II/Lab  HONS 155/155L: Honors Geology I/Lab  HONS 156/156L: Honors Geology II/Lab  HONS 159/159L: Honors Astronomy I/Lab  HONS 160/160L: Honors Astronomy II/Lab  HONS 192/192L: Honors Organic Chemistry I: Applications of Molecular Structure and Properties/Lab: Purification, Separation and Characterization of Organic Compounds  HONS 293/293L: Honors Organic Chem II/Lab  HONS 216: Conceptual Tour of Contemporary Mathematics  HONS 294/294L: Mathematical Treatment of Equilibrium and Kinetics, Intro to Nuclear Chem/Chemical Principles Laboratory  HONS 381: Computer Music on a Laptop  HONS 499: Natural Fractal Structure, Independent Study Contributions to the First Year Experience The School also continued its strong commitment to the First Year Experience. Faculty participated interdisciplinary learning communities as well as offer individual seminars. Offerings included:  Learning Communities  CHEM 111 & 111L/BIOL 111: Chemistry and Biology for Pre‐Med Students  HTMT 210/MATH 104: Measuring the Impacts of Tourism in Charleston  ENGL 110/BIOL 111: Microbes: Friend or Foe?  BIOL 111/PYSC 103: Gateway to Neuroscience  CITA 180/MUSC 131: Introduction to Computer Music and Aesthetics: Programming Music, Performing Computers  First Year Seminars  FYSE 108: Molecular Biology in the News, BIOL  FYSE 112: Android App Development for the Liberal Arts, CSCI  FYSE 112: The Science of Secrecy, CSCI  FYSE 112: Technology, Innovation, and Sustainability, CSCI  FYSE 117: Understanding Environmental Pollution, GEOL/CHEM  FYSE 130: Physics of Sports, PHYS Distance Education 15 School of Sciences and Mathematics Annual Report 2014‐2015 The popularity of online courses in computer science and mathematics continues to grow and these two departments are listening. In 2014‐2015, the following online course offerings were made:  CSCI 110: Computer Fluency  CSCI 112: Communications Technology and the Internet  CSCI 392: Seminar on Computing & Society  CSCI 490: NGAL Software Entrepreneurship  CSCI 490: Computer Network Design, Implementation and Security  CSCI 490: Information Security Principles  MATH 101: College Algebra  MATH 103: Contemporary Math with Applications  MATH 104: Elementary Statistics The need to provide hands‐on laboratory experiences limits the feasibility of on‐line courses in natural science programs. However, Biology was able to provide some online lecture courses for a second time this summer session. They were:  BIOL 101: Concepts/Apps in Biology I  BIOL 102: Concepts/Apps in Biology II  BIOL 111: Intro to Cell Molec Biology  BIOL 112: Evol, Form & Func of Organisms Interdisciplinary Course/Course in Other Schools The School’s two interdisciplinary minors, Environmental Studies and Neuroscience, are shared with the School of Humanities and Social Sciences. Both continue to be popular among students and discussions to move both minors to a major continue. Enrollment for the Computing in the Arts major continues to grow and maintain support from the School of the Arts. Classes offered by the Department of Geology and Environmental Geosciences support an interdisciplinary major and minor in archaeology offered by the Schools of the Arts; Humanities and Social Sciences; Languages, Cultures, and World Affairs; and Sciences and Mathematics. Although not a shared program, the Department of Biology now finds itself servicing large numbers of students from the School of Education, Health, and Human Performance (EHHP) who are majoring in Public Health, Exercise Science, and Athletic Training. International/Global Initiatives Summer study abroad programs for the 2014‐2015 academic year included:  TRUJILLO, SPAIN, Faculty Directors Gorka Sancho and Deborah Bidwell BIOL: Students studied Natural History of Spain and Conservation Biology in Fall 2014.  BRITISH VIRGIN ISLANDS, Faculty Directors Rusty Day and Phil Dustan, BIOL: Students studied biology, ecology, and conservation of the Caribbean coral reef ecosystem.  ECUADOR, Faculty Director John Chadwick GEOL lead students on an in‐depth field experience through the volcanic region near Quito, Ecuador and in the volcanic Galapagos Islands. The course linked geology and evolution.  INDONESIA, Faculty Director Phil Dustan BIOL: Located in the province of Bali, this program introduced students to the natural and human ecology of the tropics, explore 16 School of Sciences and Mathematics Annual Report 2014‐2015 

the complex and distinctive natural features of tropical communities and become familiar with ecological processes at they apply to tropical ecosystems. PANAMA, Faculty Director Craig Plante, BIOL: The course fulfilled a lecture and lab course in ecology required for marine biology majors. A significant portion of the lab was spent in the tropical setting. GERMANY, Faculty Directors Chris Korey BIOL and Michael Ruscio; Exposed students to neuroscience research and training conducted by the consortium of the German Schools of Neuroscience (GSN). Students interact with leading researchers through seminar style lectures, laboratory tours and demonstrations. Dr. K. Alem Ali and Cynthia Hall, GEOL traveled to Africa this summer to begin laying the groundwork for a new study abroad offering that will be available in the Summer 2016. Additional Programs and Centers The BEnthic Acoustic Mapping and Survey (BEAMS) Program completed its 8th year at the College. Housed within the Department of Geology and Environmental Geosciences, the program trains geology and marine biology students in the use of state‐of‐the‐art technology and software, to study in detail the ocean’s seafloor. The program is designed to address the omnipresent need for qualified ocean surveyors to support the expanding academic opportunities and job market in bathymetric mapping, seafloor habitat characterization, hydrography, marine spatial planning, water column process, marine geology and geophysics research, and remote observation of the ocean’s variability through time. The College’s BEAMS student alumni have become recognized internationally for their knowledge of and experience with mapping technologies. Santee Cooper Geographic Information Systems Laboratory is a center for excellence in geographic information systems (GIS) and remote sensing. It supports undergraduate, graduate, and faculty teaching and research, facilitates education and outreach, and trains students in GIS software. The lab also provides data and support for community and regional groups:  SCGIS maintains a base station on the roof of the science building that serves as part of the state’s emergency management plan allowing first responders to use differential GPS during emergencies and disasters.  The lab is a source of information about the Charleston Seismic Zone providing educational information for K‐higher education users as well as the general public.  A partner of the United States Geologic Survey, the Center is a data site for the National Map program.  The lab supports FEMA’s HAZUS‐MH program by holding certification workshops at the College.  The lab supports the South Carolina Arc Users Group and South Carolina Mapping Advisory Committee.  The lab supports South Carolina Earthquake Education and Preparedness. 17 School of Sciences and Mathematics Annual Report 2014‐2015 South Carolina Space Grant Consortium (SCSGC) is part of a nationwide network that promotes aerospace research, K‐12 and college education, and public awareness of NASA mission directorate initiatives. Within the larger context of national STEM initiatives, SCSGC promotes activities in research, education, and public engagement related to NASA’s mission. The College of Charleston serves as the lead institution for the SCSGC and SC NASA EPSCoR and the College acts as the Consortium’s legal and fiscal agent for both programs. SCSGC’s goals and objectives are: to increase access and understanding of space, Earth systems science, biological sciences, and aeronautics; encourage cooperative programs among colleges and universities, state organizations, business and industry, and pre‐college interests; enhance interdisciplinary research, education and public service activities; recruit and train students, educators, and professionals, especially women and underrepresented groups; promote a strong STEM base in SC education; facilitate statewide communication of NASA opportunities and programs. Students who work closely with this program have gone on to internships and jobs with NASA’s Goddard Space Center and Johns Hopkins Applied Physics Laboratory. Lowcountry Hall of Science and Math is the education/public engagement arm of the College of Charleston’s Schools of Sciences and Mathematics (SSM), serving as a critical bridge between science and math faculty and educators. The LHSM provides a mechanism for communication and collaboration between SSM, the School of Education, Health and Human Performance (EHHP), regional educators, and the general public. The philosophy of the LHSM is providing the classroom teacher with a strong science and math education, the first step in achieving a solid knowledge base and hands‐‐ on understanding of the natural world. Since its inception in 1997, the LHSM has reached tens of thousands of students through the Lowcountry Regional Science and Engineering Fair (hosted by LHSM), SSM open houses at the College of Charleston, Community‐‐ wide STEM Festivals and Education Days, Science and Math nights, etc. The LHSM has reached thousands of teachers through STEM professional development opportunities and as a resource library of STEM curricula for pre‐‐‐ and in‐‐ service teachers. South Carolina Earthquake Education & Preparedness Program (SCEEP) is composed of Geology faculty members whose broad research interests encompass everything from the cause of earthquakes to their likely effects and then share that information with the public and the appropriate emergency management groups. The group is funded by the SC Emergency Management Division and is responsible for promoting earthquake safety and examining hazards on a statewide basis. DIVERSITY Faculty Recruitment Efforts The School’s roster of 137 faculty members has risen to 46% females, the largest underrepresented group in STEM fields, and approximately 20% of ethnicities other than Caucasian or of foreign descent. A comparison of recent percentage of women and minorities receiving terminal degrees in various STEM fields, and our employment percentages in those 18 School of Sciences and Mathematics Annual Report 2014‐2015 fields is shown below. The comparison shows that SSM is a leader in providing fair employment opportunities to both demographic groups. Minorities Women CIP Discipline IPEDS CofC IPEDS CofC 11 Computer and Information Science and 12.3% 23.1% 19.4% 23.1% Support Services 26 Biological and Biomedical Sciences 18.4% 12.8% 53.6% 30.7% 27 Mathematics and Statistics 9.7% 43.7% 29.1% 34.3% 40 Physical Sciences 10.0% 13.7% 34.0% 32.0% When advertising for faculty positions, search chairs allocate additional funds to advertise in media available to minority audiences such as the Association for Women in Science and the Society for the Advancement of Native Americans and Chicanos in Science and the National Organization for the Professional Advancement of Black Chemists and Chemical Engineers. Advertisements are also sent to institutions known to have large numbers of minority PhD students such as Howard University, Alabama A&M, Florida International University, and University of Puerto Rico. Academic requirements remain a priority in regards to potential hires. During the 2014‐2015 academic year four, new roster faculty members began teaching in four of the six academic departments. 



BIOL: Assistant Professor, Daniel McGlinn, Caucasian Male, Ph.D. Oklahoma State University CHEM: Assistant Professor, Katherine Mullaugh, Caucasian Female, Ph.D. University of Delaware MATH: Assistant Professor, Justin Webster, Caucasian Male, Ph.D. University of Virginia PHYS: Assistant Professor, Ian Rumsey, Caucasian Male, Ph.D. North Carolina State University Student Diversity Efforts The South Carolina Alliance for Minority Participation (SCAMP) is an initiative of the National Science Foundation and is aimed at encouraging minorities to pursue degrees in STEM areas. A major goal of the program is to increase the number of underrepresented minorities receiving baccalaureate degrees in these areas. The long‐term goal is to increase the number of students matriculating in graduate studies in STEM fields. It is a subset of the Louis Stokes‐AMP national program. In South Carolina, the consortium is made up of the College of Charleston and nine other institutions of higher learning, with South Carolina State University serving as the lead institution. 19 School of Sciences and Mathematics Annual Report 2014‐2015 The Summer Bridge Program for SCAMP is held in conjunction with SPECTRA during Summer II Session. SCAMP students register for the college level Pre‐calculus and accompanying Lab and work with tutors to help them succeed. The department of chemistry and biochemistry began offering a pre‐CHEM 111 course for twelve students who participated in the SCAMP/SPECTRA Summer Bridge program, CHEM 103. The participating students in this course for the past three summers had an average CHEM 111 grade of 3.06. The average Fall CHEM 111 grade is 2.6‐2.7. The average Fall CHEM 111 grade for underrepresented minorities students is 1.89. Currently 35 students participate in SCAMP with 9 new students currently enrolled in SPECTRA. Some recent graduate accomplishments include:  Casey Wadsworth ’14: Accepted to MUSC College of Medicine  Lidoshka Marc ’14: Employed at Mead Westvaco as Associate Applications Chemist  Tomika Caldwell ’14: Attending MS Immunology program at MUSC  Briosha Sanders ’14: program Assistant of Expecting Health, at Genetic Alliance in Washington, DC  Jan Enabore ’14: Accepted to USC Greenwood Medical School  Tiffani Smalls ’14: Studying Nursing at MUSC  Joye Nettles ’15: Software Developer at ThoughtWorks Women in Computing is an initiative of the Department of Computer Science. Despite the high female population at the College as a whole, the majority of majors in computer science disciplines are males. The goal of this new organization is to increase the number of female majors by focusing on female mentoring by female faculty. Under the direction of RoxAnn Stalvey, number of female majors in the department has risen to 24% of its student body. The national average is 18%. Two external grant programs, the Howard Hughes Medical Institute (HHMI) and the South Carolina National Institutes of Health IDeA Networks of Biomedical Research Excellence (SC INBRE), help support undergraduate research and in particular emphasize the inclusion of underrepresented minorities. The School’s complete diversity report can be found in Appendix C. ASSESSMENT ACTIVITES Assessment takes place at both the school‐wide and departmental/programmatic levels. School‐wide assessment looked at what type of faculty provide instruction in our introductory general education courses, how many students participated in undergraduate research, and laboratory safety. The results show that we need additional lines to provide roster faculty to teach in introductory lectures and thus lessen our dependency on adjuncts (54.8% of intro students are taught by adjuncts), that we continue to provide research opportunities to over 200 students each year and that we require more resources to provide similar opportunities to more students (234 for credit in FY14, 217 for credit in FY15), and that our safety efforts continue to improve (departmental safety committees are becoming more 20 School of Sciences and Mathematics Annual Report 2014‐2015 active). Departments assessed aspects of their program that were important to them. The School’s complete assessment report can be found in Appendix D. STUDENT ACCOMPLISHMENTS Undergraduate/Graduate Research Undergraduate research remains a priority and a high impact experience for Science and Math majors. This experience often results in students presenting their research findings at regional and national conferences and/or being published alongside their faculty mentors in peer reviewed journals. This credit is invaluable for graduate and professional health school applications and further prepares students for their graduate studies. Each year approximately 250 students work in a research lab with approximately 50 experiences resulting in student author credit on an article published in a refereed scientific journal. In November 2014, the School held its now annual research match‐making session which introduced faculty mentors to undergraduates eager for a high impact research experience. Approximately 150 students stopped by to meet with researchers from our six academic departments and the Medical University of South Carolina. Dozens of students were matched to a faculty mentor and began working in labs in Spring 2015. SSM students were awarded a total of 76 research grants from the Office of Undergraduate Research and Creative Activities. These grants provide funds for materials, stipends for summer research, and cover travel fees to conferences and meetings. A complete list of awards and abstracts can be found in Appendix E. The 26th Annual Undergraduate Research Poster Session featured 132 posters representing the work of 218 authors. A complete list of abstracts can be found in Appendix F. SSM students also presented at campus events such as the Graduate School Poster Session , Neuropalooza, and Celebration of Scholars. In the Spring of 2015, the Dean of the School of Sciences and Mathematics awarded twenty students with stipends to support a summer research project. Students presented research at regional and national conferences often winning scholarships and awards. Conferences and meetings include: SYNAPSE annual meeting; Society for Integrative Comparative Biology; American Chemical Society; US HYDRO Conference; American Fisheries Society Southeastern Division; Southeastern Society of Parasitologists; Southeastern Developmental Biology Conference; Southeast Enzyme Meeting; Lunar and Planetary Sciences Conference; Geological Society of America; USA CARIS 2015 Conference. Some Awards and Distinctions: 21 School of Sciences and Mathematics Annual Report 2014‐2015 
BEAMS Students swept the US Hydro academic poster session awards, receiving cash awards totaling $3000.  Alannah Aldstadt: Awarded a Fulbright Teaching Assistantship in Germany  Samantha Nicolau: Northwestern University, Ph.D. program in Biology  Aliya Dumas: International Research Experience at Nanyang Techological University in Singapore  Madeline Gordon: NIST Fellowship; Best Oral Presentation Award, SERMACS  Nathan Adamson; Duke University, Ph.D. program  Tyler Perini: As part of the Harry and Reba Huge Foundation grant, studied at the University of Tartu in Estonia in spring 2015  Steve Gorman, Mike Lis, John Sussingham: Worked on US Olympic Committee research projects using mathematics to rank US athletes.  Kate O’Dell: First place in SC Academcy of Sciences in Earth Sciences  Mathematics Students Sweep Conference Awards at 2014 SEINFORMS Conference  Derek Novo ’15: GEM Fellow admitted to Columbia University’s Fu Foundation School of Engineering and Applied Science.  Society of Physics Student Organization: Named Distinguished SPS Chapter External Scholarships  Nathan Adamson: Goldwater Scholarships  Brenna Norton Baker: Goldwater Scholarship  Sharleen Johnson: Harry Hampton Wildlife Fund/Guy Harvey Ocean Foundation Scholarship Select Faculty Awards and Distinctions  Scott Harris: Fulbright Award  George Chartas: College of Charleston Distinguished Research Award  George Chartas: Gordon E. Jones Distinguished Achievement Award  Wendy Cory: Outstanding Outreach Volunteer Award, South Carolina Section, American Chemical Society Recent Press  Anton Dumars: Forget Outside the Box – This Professor Thinks Outside the Boat  Joye Nettles: Bucking the Trend: College of Charleston Senior Joye Nettles is Computer Science Star  Gorka Sancho: Saving the Waves: US Leads the Way on Protecting Oceans  BEAM Team: College Seafloor Mappers Sweep Awards  Jessica Brewer ’98: Women in Business: Jessica Brewer, Senior Vice President of Engineering and Global Services  Jim Bowring: CofC Professor Part of NSF’s $31 Million to Improve Big Data 22 School of Sciences and Mathematics Annual Report 2014‐2015 

Cassandra Runyon: Geology Professor’s Commitment to Students and Science is Rock Solid Zach Brooker: Summer Internship in Alaska Gets Biology Major Up‐close to Nature Promotional Videos  Species Evolution – Mapping the Evolutionary Tree of Sharks and Rays  Black Hole Accretion Disks, Developing Computer Simulations  Chemical Rescue of a Mutant Version of a Computationally‐designed Enzyme  Ewan Oglethorpe ’12, Data Scientist  “Selfies” and the Mobile App Entrepreneur  $100,000 Grant for Genomics Undergraduate Research  Academy Award Winning Visual Effects Artist Discusses Motion Graphics and Movies  Undergraduate and Graduate Students Focus on Marine Research  Marine Biology Internship, Coral Reef and Shark Research Medical School Acceptances The 2014‐2015 academic year saw an increase in student activity drawn from a pool of prospective students, currently enrolled students, transfer students, and alumni. An average of 30 students per week visited the Health Professions Advising Office. Of these, 139 students were accepted to professional schools including clinical programs in the following areas: medicine, dental, veterinary, pharmacy, allied health, and nursing. 60 students were accepted to medical schools (both MD and DO). Trends in medical school applications are changing and approximately 50% of students are applying the year they graduate rather than starting medical school immediately after graduation; taking a gap year. This trend has been well received by medical schools, but it presents new challenges in accurate student tracking. Since the launch of Banner, the College’s software system, the pre‐health category helps to identify and track incoming pre‐health students. As of June 2015, more than 700 students were designated as pre‐health students with an assigned pre‐health advisor. Pre‐Health Peer Mentors have recently been made available to make pre‐health information more accessible to all interested pre‐health students at the College. Student to student interaction has proven to be very successful. The first annual Military Night was held on September 17, 2014. The purpose of the event was to offer pre‐health students the opportunity to learn about the various military scholarship opportunities offered through various branches of the military and to heighten awareness of students for those who serve in the military and the sacrifices they make that benefit everyone. The event was very popular and attracted a diverse group of students from across campus. It will continue as an annual collaborative event between SSM and local military recruiters. 23 GRANTS‐NEW
APPENDIX A
ORGA Number Date Funded
BIOL
BIOL
Federal
Federal
2015‐109
2015‐117
2012‐003S
4/6/2015 deburoni
5/14/2015 deburoni
7/1/2014 burnettl
BIOL
BIOL
BIOL/GML
Federal
Private
Federal
Field Optimization of a Recently Developed qPCR Tool for Detection of an Invasive Parasite of American Eels
Blood fluke parasites of the spotted seatrout in North Inlet, SC: species identification and life cycle
Supplement: RUI: Elevated envionmental CO2 impairs acclimation to hypoxia in crustaceans
US Fish and Wildlife Service
Belle W. Baruch Foundation
National Science Foundation
2014‐070
7/15/2014 leep
2011‐100D 10/4/2014 naylorg
2011‐100E 10/4/2014 naylorg
2015‐116A 4/19/2015 brews
2014‐063
8/19/2014 ditullioj
2015‐027
8/29/2014 deburoni
2014‐003C 10/9/2014 ditullioj
2015‐074 12/18/2014 burnettk
2014‐003D 4/16/2015 ditullioj
BIOL/GML
BIOL/GML
BIOL/GML
BIOL/GML
BIOL/GML
BIOL/GML
BIOL/GML
BIOL/GML
BIOL/GML
Federal
State
State
Private
Federal
Federal
Private
Private
Private
MUSC
MUSC
Slocum‐Lunz Foundation
SC Department of Natural Resources
Universiry of South Florida
Sigma Xi
University of South Florida
2011‐022S2
6/9/2015 naylorg
BIOL/GML
Federal
2011‐057R
2011‐040E
2012‐038C
7/26/2014 coryw
7/1/2014 deavorj
9/9/2014 gelascop
CHEM
CHEM
CHEM
Federal
Federal
Private
2015‐056
11/5/2014 guirgisg
CHEM
Private
2015‐090
2/24/2015 tonksn
CHEM
Private
RUI: Vitamin B12 and nitrogen regulation of oceanic dimethylsulfoniopropionate (DMSP) and dimethylsulfide (DMS)
Centers of Economic Excellence‐Marine Genomics
Student Research Stipends
MRI: Acquisition of a field‐deployable mass spectrometer for biogeochemical research and education
Detenction of an Invasive parasite of American Eels using qPCR
Center for Integrated Modeling and Analysis of the Gulf Ecosystem (C‐Image)
Quantification of hemocyanin forms in the Pacific white‐leg shrimp following hypoxic exposure
REU Supplement: Collaborative Research: Jaws and Backbone: Chondrichthyan Phylogeny and a Spine for the Vertebrate Tree of Life
RUI: Photochemical Degradation, Soil Sorption, and Environmental Fate of Pharmaceutically active Compounds in Simulated and Natural Water Samples
Building Biomedical Research Pathways in Genetics, NeuroBIOL, and Chemical BIOL
2014 Undergraduate Science Education Completion
Conformational studies of compounds containing a six‐membered ring system consisting of silicon and other atoms in the cyclic backbone
Pontamne Blue 3R, the optimization of the synthesis process for Direct Blue 71 to form a stable liquid formulation starting with Casella acid/a‐Napthylamine
Kemira
3/1/2015 funded
$20,000
2015‐083
2015‐070
5/5/2015 boucherds
5/11/2015 mullaughkm
CHEM
CHEM
Federal
Private
National Institute of Standards and Technology
Oak Ridge Associated Universities
5/1/2015 funded
6/1/2015 funded
$8,942
$5,000
CHEM
CSCI
CSCI
CSCI
Private
Federal
Federal
Federal
Summer Undergraduate Research Fellowship Program‐Gaithersburg
Ralph E. Powe Junior Faculty Enhancement Award
Employing Light Scattering Analysis and Zeta Potential Measurements to Study the Assembly and Stability of Poly(3‐
Hexylthiophene) in Binary Solvent Mixtures REU Site: Next‐Generation Bioinformatics for Genomics‐enabled Research in the Life Sciences
Collaborative Research: Cyberinfrastructure for Interpreting and Archiving U‐series Geochronologic Data
EarthCube Test Enterprise Governance: An Agile Approach
CSCI
Private
Red Drum Sequencing
CSCI
GEOL
GEOL
GEOL
GEOL
GEOL
GEOL
GEOL
Federal
Federal
Federal
Federal
Federal
Federal
Federal
State
Computational Genomics Support, 2015‐2020
Sources, Fate, and Transport of Contaminants in Engineered Stormwater Structures
SCEMD/FEMA funding 2015
SSERVI‐UCF, Year 2
SSERVI‐Brown‐MIT, Supplement
NASA ESPSCoR 2014 Research‐Chen Li, USC
Research Infrastructure Development 2012‐2016
Saltwater Interface Project
Landscape evolution and geoarchaeology of the OCS: prehistoric maritime cultural resources in South Carolina
Blueways‐Greenways: Developing Examples as Models for Other Communities Understanding Coastal Vulnerability in the ACE Basin National Estuarine Research Reserve: A Multifaceted GIS‐Based Approach
1/1/2015 andersonp
2015‐141
6/11/2015
2015‐061
3/20/2015
2015‐130
6/24/2015
2013‐095B 5/21/2015
2013‐094S 6/15/2015
2015‐017
8/7/2014
2013‐011C 9/16/2014
2015‐046 10/14/2014
anderspe
vuluvav
levinen
runyonc
runyonc
runyonc
runyonc
callahant
2015‐021
2015‐039
11/11/2014 harriss
11/11/2014 levinen
GEOL
GEOL
Federal
Federal
2015‐035
11/11/2014 levinen
GEOL
State
Status
Amount Funded
6/15/2015 rutterm
8/28/2014 clarkaj
2015‐071
Sponsor
Anticip Start Date
2014‐008B
2014‐007
boucherds
andersonp
bowringj
bowringj
DEPT/UNIT
Funding Source
Project Title
RUI: Collaborative: unPAK: undergraduates Phenotyping Arabidopsis Knockouts: A distributed genomic approach to examine evolutionary important traits
Collaborative IOS Full Proposal: RUI: Biting hard with soft feeding apparatuses
2015‐043
6/8/2015
2014‐010
7/1/2014
2014‐081
8/25/2014
2013‐100B 11/25/2014
PI ID
Co‐PI ID
6/1/2014 funded
9/1/2014 funded
$208,574 murrenc
$116,067
9/1/2015 funded
7/1/2015 funded
3/1/2012 funded
$0
$5,000
$15,201 burnettk
9/1/2014
7/1/2010
7/1/2010
4/19/2015
9/1/2014
8/1/2014
10/9/2014
1/16/2015
4/14/2015
funded
funded
funded
funded
funded
funded
funded
funded
funded
National Science Foundation 2/1/2011 funded
SC‐INBRE
Howard Hughes Medical Institute 9/1/2012 funded
4/1/2010 funded
9/2/2012 funded
Camille & Henry Dreyfus Foundation
American Chemical Society
University of Arizona
SC Department of Natural Resources/SC Sea Grant Consortium
National Oceanic and Atmospheric Administration
SC Sea Grant Consortium
SC Emergency Management Division
University of Central Florida
Brown University
NASA
NASA EPSCoR
University of South Carolina
11/1/2014 funded
6/1/2015
10/1/2014
9/1/2014
9/1/2014
funded
funded
funded
funded
1/1/2015 funded
6/15/2015
3/2/2015
6/24/2015
11/1/2013
11/1/2013
7/9/2014
10/19/2012
10/15/2014
funded
funded
funded
funded
funded
funded
funded
funded
$894,664 ditullioj
$164,356 hilleniusj
$134,257 hilleniusj
$3,586
$574,942
0
$900
$500
$6,150
Co‐PI ID
stranda
auerbachmj
auerbachmj
$99,176
$100,728 vulavav
$132,516
$350,000
$20,000
$70,000
$334,662 shedlockam
$579,762
$20,000
$5,000
$2,826
$25,000
$19,236
$50,000
$40,500
$749,998
$125,000
$37,500
11/1/2014 funded
11/1/2014 funded
$21,987
$25,000
10/18/2014 funded
$6,635
beckinghamb
beutele
hallcr
hallcr
callahant
GRANTS‐NEW
APPENDIX A
PI ID
DEPT/UNIT
Funding Source
2013‐107R
2015‐098
2015‐101
2/10/2015 callahant
2/16/2015 callahant
2/25/2015 sautterl
GEOL
GEOL
GEOL
Federal
Private
State
2012‐019C
2012‐096D
2015‐069
Internal
2015‐105
2015‐044
3/2/2015
3/23/2015
4/29/2015
5/29/2015
6/3/2015
11/1/2014
GEOL
GEOL
GEOL
GEOL
GEOL
MATH
State
Federal
Federal
Federal
Federal
Federal
2015‐072
1/22/2015 jonesm
MATH
Private
2015‐010
2013‐129
2014‐002B
2015‐032
2012‐069C
2010‐076R
7/22/2014
7/31/2014
8/1/2014
4/1/2015
4/14/2015
6/8/2015
PHYS
PHYS
PHYS
PHYS
PHYS
PHYS
Federal
Federal
Federal
Federal
Federal
Federal
callahant
runyonc
callahant
alika
runyonc
websterj
carsonjc
chartasg
neffj
chartasg
larsenml
oprisans
Project Title
Sponsor
Development of monitoring and assessment tools for nitrogen and phosphorus in South Carolina coastal wetlands II: hydrological assessments
2015 IASNR Conference
U.S. Hydro 2015 Conference Student Travel
International Association for Society and Natural SC Sea Grant Consortium
SC Department of Transportation/SC Department Stringer Creek Hydrology
of Natural Resources
UAH‐CofC NASA Space Missions Design
The University of Alabama in Huntsville
JFA (USGS): Monitoring Stream Flow in the Turkey Creek Watershed, Francis Marion National Forest, South Carolina
US Forest Service/US Geological Services
Monitoring the effect of watershed development and climate change on the marine wetlands in the U.S. Virgin Islands Research Infrastructure Development
NASA EPSRoR 2015 Flow‐thru: UVI
NASA EPSCoR
Analysis and Control of Mathematical Models of Fluttering Plates
POST‐INSTITUTE IMPLEMENTATION SENCER NSF 2014‐2016 SUB‐AWARDS
Decoding Debris System Substructures: Imprints of Planets/Planetesimals and Signatures of Extrinsic Influences on Material in Ring‐Like Disks
Unveiling the x‐ray/UV connection in AGN Winds: The PG 1126‐041 Case Study
NSF IPA
AGNs Formed in Protogalaxies Associated with Sub‐DLAs
Spatial Variability (Structure) in Rain
Year 5: CAREER
National Center for Science and Civic Engagement
Hubble/NASA
Space Telescope Science Institute
Chandra Observatory at Harvard University
Anticip Start Date
Status
10/1/2014 funded
3/1/2015 funded
3/1/2015 funded
2/17/2015
3/15/2015
4/29/2015
10/1/2014
1/1/2016
10/1/2014
$92,879
$92,457
$800
funded
$7,520
funded
$5,000
funded
$13,211
funded
$18,000
funded
$748,026
funded (tra $110,277
1/1/2015 funded
6/1/2014
8/12/2013
3/23/2015
9/15/2012
4/1/2011
Amount Funded
funded
funded
funded
funded
funded
funded
$3,000
$0
$39,655
$129,069
$70,465
$44,098
$90,000
$6,438,122
Co‐PI ID
Co‐PI ID
GRANTS‐ACTIVE
APPENDIX A
PI ID
DEPT/UNIT
Funding Source
Project Title
Sponsor
Research Program
Collaborative:RUI:Quantifying mutation parameters in a fitness landscape: spontaneous mutation in A. thaliana in its National Science Foundation
REU Supplement: Arabidopsis 2010 Collaborative Reserac: RUI: Quantifying mutation parameters in a fitness landscape: Spontaneous mutation in A. thaliana in
REU Supplement: Arabidopsis 2010 Collaborative Reserac: RUI: Quantifying mutation parameters in a fitness landscape: Spontaneous mutation in A. thaliana in
Collaborative: Analytical techniques and software: Development of cyberinfrastructure to support laser‐ablation ICP National Science Foundation
Collaborative: Analytical Techniques and Software: Development of CyberInfrastructure to Support Laser‐Ablation ICP National Science Foundation
2007‐109
2009‐009
1/31/2007 beamc
8/25/2009 rutterm
CHEM
BIOL
Private
Federal
2009‐009S
5/11/2010 rutterm
BIOL
Federal
2009‐009S2
2009‐084
2009‐084B
2009‐084C
2009‐084S
1/26/2011
5/24/2010
4/15/2011
4/5/2012
6/25/2014
BIOL
CSCI
CSCI
CSCI
CSCI
Federal
Federal
Federal
Federal
Federal
2009‐124
3/23/2010 zimmermana
2009‐124B 3/26/2012 zimmermana
2010‐048D 10/19/2012 dustanp
2010‐048E 12/5/2013 dustanp
2010‐051
7/14/2010 carsonjc
BIOL
BIOL
BIOL
BIOL
PHYS
Federal
Federal
Private
Private
Federal
2010‐064
2010‐064S
2010‐074
2010‐074B
2010‐074B
2010‐074B
2010‐074C
2010‐074D
2010‐074E
2010‐074S
8/31/2010
1/9/2012
7/16/2010
9/9/2011
5/3/2012
9/10/2010
7/23/2012
6/11/2013
12/2/2013
8/19/2010
BIOL
BIOL
GEOL
GEOL
GEOL
GEOL
GEOL
GEOL
GEOL
GEOL
Federal
Federal
Federal
Federal
Federal
Federal
Federal
Federal
Federal
Federal
2010‐076R
3/25/2011 oprisans
PHYS
Federal
2010‐076R
8/8/2011 oprisans
PHYS
Federal
PHYS
PHYS
PHYS
CSCI
CSCI
CSCI
GEOL
GEOL
GEOL
BIOL
BIOL/GML
BIOL
BIOL
BIOL/GML
BIOL/GML
BIOL/GML
Federal
Federal
Federal
Federal
Federal
Federal
Federal
Federal
Federal
Federal
Federal
Federal
Federal
Federal
Federal
Federal
(RUI): Targeted Annotation and Exploration of Synteny of Immunoglobulin Ioci in Teleosts Using RSS Motifs
(RUI): Targeted Annotation and Exploration of Synteny of Immunoglobulin Ioci in Teleosts Using RSS Motifs
Year 4: Continuation of ecological watershed studies on BP lands
Year 5: Continuation of ecological watershed studies on BP lands
RUI: Ground‐Based and Space‐Based Direct Imaging Surveys for Extrasolar Planets
RUI: Fine root production and architecture in a loblolly pine forest exposed to FACE: Interactive effects of atmospheric CO2 enrichment with soil N availability
Supplement for RUI: Fine root production and architecture in a loblolly pine forest exposed to FACE: Interactive effects Space Grant Year 18
Space Grant Year 19
SCSGC Year 19 Augmentation
SCSGC Year 18 Augmentation
SC Space Grant Year 20, 2012‐2013
Space Grant Year 18
CAREER: Prediction of Synchrony and Phase‐Locked Modes in Neural Networks based on Stimulus Time Resetting Curve
Year 2 CAREER: Prediction of Synchrony and Phase‐Locked Modes in Neural Networks based on Stimulus Time Resetting Curve
Year 2 Supplement CAREER: Prediction of Synchrony and Phase‐Locked Modes in Neural Networks based on Stimulus Time Resetting Curve
Year 3: Supplement CAREER
Year 4: CAREER
Year 2: Collaborative Research: Scaling up an innovative approach for attracting students to computing
subaward to USC (Reynolds)
sub to clemson (Chen)
Monitoring Stream Flow in the Turkey Creek Watershed, Francis Marion National Forest, South Carolina
Collaborative: RUI: Engaging undergraduates in genomic questions and environmental context: building a database of Collaborative Research: Cascading effects of an invasive seaweed on estuarine food webs of the southeastern US
RUI: Integrating roots into whole plant phenotypes: ecological and genetic perturbations
RUI: Integrating roots into whole plant phenotypes: ecological and genetic perturbations
Collaborative Research: Jaws and Backbone: Chondrichthyan Phylogeny and a Spine for the Vertebrate Tree of Life
REU Supplement: Collaborative Research: Jaws and Backbone: Chondrichthyan Phylogeny and a Spine for the REU Supplement: Collaborative Research: Jaws and Backbone: Chondrichthyan Phylogeny and a Spine for the rutterm
bowringj
bowringj
bowringj
bowringj
pritchards
pritchards
runyonc
runyonc
runyonc
runyonc
runyonc
runyonc
runyonc
runyonc
2010‐076R
2010‐076R
2010‐076R
2010‐077B
2010‐077C
2010‐077D
2010‐087
2010‐088
2010‐096E
2011‐005
2011‐007
2011‐008R
2011‐008R
2011‐022
2011‐022S
2011‐022S2
9/23/2011
8/13/2013
2/12/2014
5/3/2012
6/17/2013
5/15/2014
8/3/2010
7/20/2010
6/9/2014
4/12/2011
3/31/2011
2/9/2012
4/30/2014
3/23/2011
3/28/2014
6/9/2015
oprisans
oprisans
oprisans
stalveyr
stalveyr
stalveyr
runyonc
runyonc
callahant
rutterm
sotkae
murrenc
murrenc
naylorg
naylorg
naylorg
2011‐025
5/11/2011 burnettl
BIOL/GML
Federal
REU Site: Research Experiences in Marine Organism Health: Resilience and Response to Environmental Change
2011‐025B
7/19/2013 burnettl
BIOL/GML
Federal
REU Site: Research Experiences in Marine Organism Health: Resilience and Response to Environmental Change
Anticip Start Date
Status
Amount Funded
2/1/2007 funded
09/01/09 funded
$5,000
$258,372
5/11/2010 funded
$7,000
1/26/2011
06/01/10
6/1/2010
6/1/2010
6/1/2010
funded
funded ‐ le
funded
funded
funded
$7,000
$127,478
$96,320
$98,113
$31,894
BP America, Inc.
BP America, Inc.
03/15/10
03/15/10
11/1/2008
11/1/2008
9/1/2010
funded
funded
funded
funded
funded
$151,570
$45,354
$1,000
$1,000
$286,568
NASA
NASA
NASA
NASA
NASA
NASA
NASA
NASA
9/1/2010
1/1/2012
6/25/2010
6/25/2010
6/25/2010
6/25/2010
6/25/2010
6/25/2010
6/25/2010
8/19/2010
funded
funded
funded
funded
funded
funded
funded
funded
funded
funded
$584,298
$7,500
$430,000
$430,000
$185,000
$185,000
$430,000
$430,000
$430,000
$35,304
4/1/2011 funded
$210,000
4/1/2011 funded
$20,000
NASA
NASA
National Science Foundation National Science Foundation National Science Foundation 4/1/2011
4/1/2011
4/1/2011
6/1/2011
6/1/2011
6/1/2011
8/16/2010
8/1/2010
6/9/2014
4/15/2011
8/1/2011
3/1/2012
3/1/2012
2/1/2011
2/1/2011
2/1/2011
Co‐PI ID
stranda
colganm
colganm
colganm
colganm
colganm
colganm
colganm
colganm
funded
funded
funded
funded
funded
funded
funded
funded
funded
funded
funded
funded
funded
funded
funded
funded
$70,000
$20,000
$90,000
$75,636
$39,088
$63,269
$750,000 colganm
$750,000 colganm
$11,680
$422,500 stranda
$265,414
$239,417
$372,225
$2,234,878
$6,000
$99,176
6/1/2011 funded
$194,900 burnettk
6/1/2011 funded
$98,550
Co‐Email
murrenc
GRANTS‐ACTIVE
APPENDIX A
PI ID
DEPT/UNIT
Funding Source
Project Title
Sponsor
Anticip Start Date
Status
Amount Funded
Co‐PI ID
2011‐040E
2011‐047R
2011‐049
7/1/2014 deavorj
8/15/2012 neffj
8/26/2011 neffj
CHEM
PHYS
PHYS
Federal
Federal
Federal
Building Biomedical Research Pathways in Genetics, NeuroBIOL, and Chemical BIOL
RUI/Collaborative Research: A Spectroscopic Survey of Circumstellar Gas in Lambda Boo Stars
Molecular Band Measurements of Absolute Starspot Properties
SC‐INBRE
4/1/2010 funded
8/15/2012 funded
6/1/2011 funded
2011‐050
8/9/2011 calinia
MATH
Federal
8/15/2011 funded
$174,104 calinia
2011‐057R
7/26/2012 coryw
CHEM
Federal
9/1/2012 funded
$133,880 vulavav
2011‐057R
2011‐063
2011‐100C
2011‐100D
2011‐100E
2011‐113
2012‐003
2012‐003B
2012‐003C
2012‐003S
7/26/2014
6/8/2011
5/11/2011
10/4/2014
10/4/2014
7/3/2012
1/6/2012
2/22/2013
2/24/2014
7/1/2014
coryw
langvillea
naylorg
naylorg
naylorg
ditullioj
burnettl
burnettl
burnettl
burnettl
CHEM
MATH
BIOL/GML
BIOL/GML
BIOL/GML
BIOL/GML
BIOL/GML
BIOL/GML
BIOL/GML
BIOL/GML
Federal
Federal
State
State
State
Federal
Federal
Federal
Federal
Federal
Collaborative Research, RUI: Nonlinear Schroedinger Models in Fluid Dynamics: Rogue Waves and Vortex Filaments
AF: Small: RUI: Ranking and Clustering by Integer and Linear Optimization
TRACERS: Tracing the fate of Algal Carbon Export in the Ross Sea
RUI: Elevated environmental CO2 impairs acclimation to hypoxia in crustaceans
Year 2: RUI: Elevated environmental CO2 impairs acclimation to hypoxia in crustaceans
RUI: Elevated envionmental CO2 impairs acclimation to hypoxia in crustaceans
Supplement: RUI: Elevated envionmental CO2 impairs acclimation to hypoxia in crustaceans
2012‐019C
2012‐038
2012‐038B
2012‐038C
2012‐042
2012‐043
2012‐062R
3/2/2015
7/5/2012
9/5/2013
9/9/2014
8/27/2012
5/25/2012
5/7/2014
callahant
gelascop
gelascop
gelascop
fragilep
carsonjc
coxbl
GEOL
CHEM
CHEM
CHEM
PHYS
PHYS
MATH
State
Private
Private
Private
Federal
Private
Private
2012‐065
8/27/2012 coryw
CHEM
Federal
2012‐069
9/19/2012 larsenml
PHYS
Federal
2012‐069B
6/22/2013 larsenml
PHYS
Federal
2012‐069C
2012‐096D
4/14/2015 larsenml
3/23/2015 runyonc
PHYS
GEOL
Federal
Federal
2012‐108R
2013‐011
2013‐011B
2013‐011C
1/16/2014
11/8/2012
8/14/2013
9/16/2014
GEOL
GEOL
GEOL
GEOL
Federal
Federal
Federal
Federal
2013‐013
8/13/2013 rutterm
BIOL
Federal
2013‐016
2/21/2013 runyonc
GEOL
Federal
2013‐017
2013‐018
2013‐025
2013‐026
2013‐030
1/31/2013
1/28/2013
1/9/2013
1/7/2013
2/12/2013
GEOL
GEOL
PHYS
PHYS
GEOL
Federal
Federal
Federal
Federal
Federal
Stringer Creek Hydrology
RUI: Numerical Simulations of Optically Thick Accretion onto Black Holes
Extrasolar Planet Imaging Studies with the Hubble and Spitxer Telescopes
Collaborative work in conformal field theory
MRI: Acquisition of an Ultra High Pressure Liquid Chromatograph ‐ Mass Spectrometer for Interdisciplinary Undergraduate Research and Teaching in Chemistry and Related Fields
Collaborative Research: Characterization of the Two Dimensional/Temporal Mosaic of Drop Size Distributions and Spatial Variability (Structure) in Rain
UAH‐CofC NASA Space Missions Design
Charleston, SC Area Earthquake Hazard Mapping Project (CAEHMP) Workshop and Pilot Study: Collaborative Research with College of Charleston and University of Memphis
Collaborative: RUI: The natural history of mutations: sequence and fitness data from A. thaliana mutation accumulation lines
Design, Manufacture, Evaluation, and Multi‐physical Modeling of Aerospace Composite Materials for Enhanced Reliability (USC Flow‐through)
Development of the Virgin Islands Center for Space Science at Etelman Observatory: Research, Education, and Economic Development through Promotion of NASA's Vision
Earthquake Mitigation Plan and Education and Outreach: South Carolina 2013‐2014
The Energetics and Shielding of FeLoBAL Quasar Outflows
Energy Dependent X‐Ray Microlensing and the Structure of Quasars
Evaluating water quality parameters in the coastal waters of South Carolina using satellite data
2013‐056
3/19/2013 welcha
BIOL
Federal
Effects of Pharmaceutical Photodegradation Products in Freshwater on Local Amphibians
jaumes
runyonc
runyonc
runyonc
runyonc
beutele
chartasg
chartasg
alika
National Science Foundation MUSC
MUSC
MUSC
SC Department of Transportation/SC Department of Natural Resources
Howard Hughes Medical Institute Howard Hughes Medical Institute Howard Hughes Medical Institute National Science Foundation
Research Corporation for Science Advancement
Simons Foundation
9/1/2012
9/1/2011
7/1/2010
7/1/2010
7/1/2010
7/15/2012
3/1/2012
3/1/2012
3/1/2012
3/1/2012
funded
funded
funded
funded
funded
funded
funded
funded
funded
funded
$100,728
$399,897
$148,483
$164,356
$134,257
$313,461
$267,476
$247,992
$231,309
$15,201
2/17/2015
9/1/2012
9/1/2012
9/2/2012
9/1/2012
7/1/2012
9/1/2014
funded
funded
funded
funded
funded
funded
funded
$7,520
$385,040 meyerbernsteinhurdm
$350,000 meyerbernsteinhurdm
$350,000
$189,653
$35,000
$35,000
9/1/2012 funded
9/15/2012 funded
$237,871
9/15/2012 funded
$43,433
The University of Alabama in Huntsville
9/15/2012 funded
3/15/2015 funded
$44,098
$5,000
US Geological Survey
NASA EPSCoR
NASA EPSCoR
NASA EPSCoR
1/16/2014
10/18/2012
10/18/2012
10/19/2012
funded
funded
funded
funded
$115,019
NASA EPSCoR
1/1/2013 funded
$750,000
funded
funded
funded
funded
funded
3/1/2013 funded
hilleniusj
hilleniusj
hilleniusj
auerbachmj
auerbachmj
auerbachmj
burnettk
burnettk
burnettk
burnettk
foxjl
$47,659 levinen
$125,000
$125,000
$125,000
1/1/2013 funded
1/1/2013
10/1/2012
1/1/2013
11/19/2012
2/1/2013
vulavav
$277,191 forconim
NASA EPSCoR
South Carolina Emergency Management Division
South Carolina Water Resources Center at Clemson University
Co‐Email
$132,516
$79,344
$166,112
$748,921 hakkilaj
$22,894 levinen
$15,000
$50,700
$9,999
$12,031 coryw
neffj
jaumes
GRANTS‐ACTIVE
2013‐067
9/10/2013
2013‐073
3/1/2013
2013‐091R 6/23/2014
2013‐094
5/30/2014
2013‐094S 6/15/2015
2013‐095
5/29/2014
2013‐095B 5/21/2015
2013‐099
1/18/2013
2013‐100
9/15/2013
2013‐100B 11/25/2014
APPENDIX A
PI ID
DEPT/UNIT
Funding Source
Project Title
Computing in the Arts: A Community‐Building Initiative
Humility, Conviction, and Disagreement in Morality; AN Interdisciplinary Investigation
MRI: Acquisition of a Bruker Avance III HD 400 High Performance Digital NMR Spectrometer with a Multinuclear probe SSERVI‐Brown‐MIT
SSERVI‐Brown‐MIT, Supplement
SSERVI‐UCF
SSERVI‐UCF, Year 2
SCUBA and video documentation of fish spawning at Gray's Reef National Marine Sanctuary
Development of monitoring and assessment tools for nitrogen and phosphorus in South Carolina coastal wetlands II: hydrological assessments
Genetic Risk Assessment Modeling for Offshore Marine Aquaculture Operations: Cobia
Defining the Role of Accessory Protein Subunits in the Assembly Mechanism of Mitochondrial Complex I
manarisb
wrightjj1
wyattj
runyonc
runyonc
runyonc
runyonc
plantec
bowringj
bowringj
CSCI
PYSC
CHEM
GEOL
GEOL
GEOL
GEOL
BIOL/GML
CSCI
CSCI
Federal
Private
Federal
Federal
Federal
Federal
Federal
Private
Federal
Federal
2/10/2015 callahant
4/30/2013 stranda
2/19/2014 foxjl
GEOL
BIOL/GML
CHEM
Federal
State
Private
2013‐122
5/13/2013 callahant
2013‐125
2/19/2014 forconim
2013‐129
7/31/2014 chartasg
2013‐135B 6/30/2014 sautterl
2014‐002
7/31/2013 neffj
2014‐002B
8/1/2014 neffj
2014‐002B
6/5/2014 neffj
2014‐003 10/24/2012 ditullioj
2014‐003B 3/24/2014 ditullioj
2014‐003C 10/9/2014 ditullioj
2014‐007
8/28/2014 clarkaj
GEOL
CHEM
PHYS
GEOL
PHYS
PHYS
PHYS
BIOL/GML
BIOL/GML
BIOL/GML
BIOL
Federal
Private
Federal
Private
Federal
Federal
Federal
Private
Private
Private
Federal
2014‐008
5/21/2014 rutterm
BIOL
2014‐008B
2014‐009
2014‐010
2014‐012
2014‐015
2014‐016
2014‐016B
2014‐017
2014‐018
6/15/2015
1/6/2014
7/1/2014
8/20/2013
4/11/2014
9/8/2013
6/2/2014
8/12/2013
1/28/2014
rutterm
sotkae
andersonp
callahant
podolskyb
andersonp
andersonp
harriss
chartasg
BIOL
BIOL/GML
CSCI
GEOL
BIOL/GML
CSCI
CSCI
GEOL
CSCI
2014‐049
2014‐053
2014‐061
2014‐063
2014‐070
2014‐081
2014‐084
2014‐086
2014‐093
2/3/2014
1/16/2014
2/25/2014
8/19/2014
7/15/2014
8/25/2014
2/18/2014
3/28/2014
5/12/2014
sanchog
sotkae
agrests
ditullioj
leep
bowringj
moorec
carsonjc
jonesl
BIOL/GML
BIOL/GML
MATH
BIOL/GML
BIOL/GML
CSCI
CSCI
PHYS
PHYS
Fishing habits and fish consumption in coastal GA
Necleophilic aromatic substitution in proteins: An old reaction for new functionalization strategies
Unveiling the x‐ray/UV connection in AGN Winds: The PG 1126‐041 Case Study
UW VISIONS '13 expedition
IPA Appointment
NSF IPA
NSF IPA‐Supplement
Collaborative IOS Full Proposal: RUI: Biting hard with soft feeding apparatuses
Federal
Federal
Detecting genetic adaptation during marine invasions
Federal
REU Site: Next‐Generation Bioinformatics for Genomics‐enabled Research in the Life Sciences
Federal
NERRS Evaluation Synthesis MES Graduate Student Landon Knapp
Federal
REU: Research Experience in Marine Organism Health: Resilience and Response to Environmental Change
Federal
Computational Genomics Support
Federal
Computational Genomics Support
Federal
Folly Beach County Park: 2‐year Renourishment Survey Program
Local
The Ultrafast Outflow of the Lensed z=1.51 AGN HS 0810+2554
Federal
The Pilot Fish Habitat Characterization Program (FishHab): Undergraduate Workforce Training in Ocean Fisheries Research
Federal
InternationPilot Project: Stacy Krueger
Tensor SUMMA Math Camp
Private
MRI: Acquisition of a field‐deployable mass spectrometer for biogeochemical research and education
Federal
RUI: Vitamin B12 and nitrogen regulation of oceanic dimethylsulfoniopropionate (DMSP) and dimethylsulfide (DMS)
Federal
Collaborative Research: Cyberinfrastructure for Interpreting and Archiving U‐series Geochronologic Data
Federal
LS‐SCAMP 2013‐2018
Federal
Imaging Search for Dynamically Inferred Planets in Nearby Debris Disk Systems
Federal
Research Assistant and Equipment Loan
Private
2014‐100
2014‐103A
2014‐103B
5/30/2014 oprisans
5/29/2014 brews
5/29/2014 brews
PHYS
BIOL
BIOL
Federal
Private
Private
2013‐107R
2013‐118
2013‐119
Sponsor
Anticip Start Date
The Templeton Foundation
Brown University
Brown University
Lux Foundation
9/1/2013
4/1/2013
8/1/2014
11/1/2013
11/1/2013
11/1/2013
11/1/2013
1/18/2013
8/1/2013
9/1/2014
funded
funded
funded
funded
funded
funded
funded
funded
funded
funded
$234,147
$240,355
$319,800
$32,400
$40,500
$52,001
$50,000
$5,000
$35,000
$20,000
National Oceanic and Atmospheric Administration‐National Ocean Service
Space Telescope Science Institute
University of Washington
10/1/2014 funded
5/1/2013 funded
7/1/2014 funded
$92,879
$22,403
$35,000
National Oceanic and Atmospheric National Oceanic and Atmospheric Charleston County Parks and Recreation
Smithsonian Astrophysical Observatory/Harvard
Marine Biological Association of the UK
Mathematical Association of America
SC State University
Jet Propulsion Laboratory
K‐Laser
REU Site: A Pilot Distributed REU Site Focused on serving PHYS Students from Comprehensive and Community Colleges Central Washington University
Graduate Student Research Support 2014 (Frede)
Graduate Student Research Support 2014 (Mealey)
5/15/2013
7/1/2013
6/1/2014
5/16/2014
8/12/2013
8/12/2013
8/12/2013
10/24/2012
10/24/2012
10/9/2014
9/1/2014
Status
funded
funded
funded
funded
funded
funded
funded
funded
funded
funded
funded
6/1/2014 funded
Amount Funded
Co‐PI ID
$24,462 mcelweetm
$35,000
$39,655
$8,636
$118,350
$129,069
$11,000
$6,810
$8,670
$900
$116,067
$281,316 murrenc
6/1/2014
3/1/2014
10/1/2014
8/16/2013
5/15/2014
8/16/2013
8/16/2013
6/15/2013
12/18/2013
funded
funded
funded
funded
funded
funded
funded
funded
funded
$208,574
$622,923
$334,662
$22,687
$272,932
$1,500
$2,950
$55,423
$61,599
5/1/2014
1/6/2014
6/1/2015
9/1/2014
9/1/2014
9/1/2014
9/15/2013
3/28/2014
5/12/2014
funded
funded
funded
funded
funded
funded
funded
funded
funded
$10,000
$2,970
$3,000
$574,942
$894,664 ditullioj
$579,762
$22,969
$5,000
$4,000
5/31/2014 funded
5/29/2014 funded
5/29/2014 funded
Co‐Email
mccauleyr
mazzonem
nadelhofferta
coryw
vanhornb
hallcr
hallcr
hallcr
hallcr
colesdp
$9,172
$1,041
$1,000
stranda
murrenc
stranda
murrenc
stranda
shedlocka@cofc.edu
sautterl
GRANTS‐ACTIVE
APPENDIX A
PI ID
DEPT/UNIT
Funding Source
Project Title
GEOL
MATH
GEOL
State
Private
Federal
Evaluation of Coastal Vunerability from Capers Island to murrells Inlet through Applied Shoreline Change Analyses
Forecasting and data collection summer research
NASA ESPSCoR 2014 Research‐Chen Li, USC
11/11/2014 harriss
8/29/2014 deburoni
4/1/2015 chartasg
GEOL
BIOL/GML
PHYS
Federal
Federal
Federal
2015‐035
2015‐039
2015‐044
11/11/2014 levinen
11/11/2014 levinen
11/1/2014
GEOL
GEOL
MATH
Federal
Federal
Federal
2015‐056
2015‐061
11/5/2014 guirgisg
3/20/2015 vuluvav
CHEM
GEOL
Private
State
Landscape evolution and geoarchaeology of the OCS: prehistoric maritime cultural resources in South Carolina
Detenction of an Invasive parasite of American Eels using qPCR
AGNs Formed in Protogalaxies Associated with Sub‐DLAs
Understanding Coastal Vulnerability in the ACE Basin National Estuarine Research Reserve: A Multifaceted GIS‐Based Approach
Blueways‐Greenways: Developing Examples as Models for Other Communities Analysis and Control of Mathematical Models of Fluttering Plates
Conformational studies of compounds containing a six‐membered ring system consisting of silicon and other atoms in the cyclic backbone
Sources, Fate, and Transport of Contaminants in Engineered Stormwater Structures
2015‐069
2015‐070
4/29/2015 callahant
5/11/2015 mullaughkm
GEOL
CHEM
Federal
Private
JFA (USGS): Monitoring Stream Flow in the Turkey Creek Watershed, Francis Marion National Forest, South Carolina
Ralph E. Powe Junior Faculty Enhancement Award
CSCI
MATH
BIOL/GML
CHEM
Private
Private
Private
Federal
Red Drum Sequencing
POST‐INSTITUTE IMPLEMENTATION SENCER NSF 2014‐2016 SUB‐AWARDS
Quantification of hemocyanin forms in the Pacific white‐leg shrimp following hypoxic exposure
Summer Undergraduate Research Fellowship Program‐Gaithersburg
Pontamne Blue 3R, the optimization of the synthesis process for Direct Blue 71 to form a stable liquid formulation starting with Casella acid/a‐Napthylamine
2014‐105
2014‐107
2015‐017
6/11/2014 levinen
6/1/2014 langvillea
8/7/2014 runyonc
2015‐021
2015‐027
2015‐032
2015‐071
2015‐072
2015‐074
2015‐083
1/1/2015
1/22/2015
12/18/2014
5/5/2015
andersonp
JonesM
burnettk
boucherds
2015‐090
2/24/2015 tonksn
CHEM
Private
2015‐098
2015‐101
2015‐105
2015‐117
2015‐141
2/16/2015
2/25/2015
6/3/2015
5/14/2015
6/11/2015
GEOL
GEOL
GEOL
BIOL
CSCI
Private
State
Federal
Private
Federal
Sponsor
SC Department of Natural Resources‐SC Geological Survey
US Olympic Committee
NASA
University of South Carolina
Amount Funded
6/1/2014 funded
6/1/2014 funded
7/9/2014 funded
$18,750
$8,000
$749,998
11/1/2014 funded
8/1/2014 funded
3/23/2015 funded
$21,987
0
$70,465
10/18/2014 funded
11/1/2014 funded
10/1/2014 funded (tra
Co‐PI ID
$20,000
$25,000 beckinghamb
Oak Ridge Associated Universities
SC Department of Natural Resources/SC Sea Grant Consortium
National Center for Science and Civic Engagement
Sigma Xi
National Institute of Standards and Technology
4/29/2015 funded
6/1/2015 funded
$13,211
$5,000
Kemira
International Association for Society and Natural Resources
NASA EPSCoR
Belle W. Baruch Foundation
National Oceanic and Atmospheric 5/6/2013 alika
GEOL
Federal
Internal
Internal
5/7/2012 alika
5/29/2015 alika
GEOL
GEOL
Federal
Federal
2015‐109
2015‐116A
2015‐116B
2015‐116C
2015‐116D
2015‐116E
4/6/2015
4/19/2015
4/19/2015
4/19/2015
4/19/2015
4/19/2015
BIOL
BIOL/GML
BIOL/GML
BIOL/GML
BIOL/GML
BIOL/GML
Federal
Private
Private
Private
Private
Private
Field Optimization of a Recently Developed qPCR Tool for Detection of an Invasive Parasite of American Eels
Claire Stegman
Ann Wassick
Kevin Mack
Mark Lehtonen
Wiley Sinkus
US Fish and Wildlife Service
1/1/2015
1/1/2015
1/16/2015
5/1/2015
funded
funded
funded
funded
$5,000
$3,000
$500
$8,942
3/1/2015 funded
$20,000
3/1/2015
3/1/2015
1/1/2016
7/1/2015
6/15/2015
9/1/2015
4/19/2015
4/20/2015
4/21/2015
4/22/2015
4/23/2015
funded
funded
funded
funded
funded
$92,457
$800
$748,026
$5,000
$2,826
6/1/2013 funded
$18,000
5/1/2012 funded
10/1/2014 funded
$18,000
$18,000
funded
funded
funded
funded
funded
funded
Co‐Email
$6,635
$25,000
$110,277
11/1/2014 funded
3/2/2015 funded
Internal
deburoni
brews
brews
brews
brews
brews
Status
Camille & Henry Dreyfus Foundation
2015 IASNR Conference
U.S. Hydro 2015 Conference Student Travel
NASA EPSRoR 2015 Flow‐thru: UVI
Blood fluke parasites of the spotted seatrout in North Inlet, SC: species identification and life cycle
Computational Genomics Support, 2015‐2020
Evaluating water quality parameters and assessing algal bloom dynamics in the coastal waters of South Carolina using hyper ‐ and multispectral sensors aboard
SC Space Grant Consortim (REAP Facilitation)
Application of Satellite Remote Sensing Techniques for Determining Water Quality Parameters in the Optically Complex Waters of Lake Erie (Palmetto Academy 2012)
SC Space Grant Consortim (REAP Facilitation)
using NASA’s ocean color sensors
NASA EPSCoR RID (Index 520987)
callahant
sautterl
runyonc
deburoni
anderspe2
Anticip Start Date
$0
$600
$350
$1,194
$842
$600
$24,782,299
callahant
Activities Database/Curriculum Vitae
APPENDIX B Date Range: Jul 01, 2014 - Jun 30, 2015
Department/Program: Biology
Publications
User
Email
Department/Program
(Most Recent)
Biology
School (Most Recent)
Publication Type
Title of Publication
Publisher
School of Sciences and
Mathematics
Journal Article, Academic
Journal
Natural history of Spain:
teaching students about
nature and culture in a
foreign country.
Journal of Natural History
and Experience
Issue Number
Page Numbers or Number Date Published
of Pages
1-8
2014
First Name
Middle Name/Initial
Last Name
Gorka
A.
Student's Major
Sancho
Student's Level
Academic Term
Year
First Name
Middle Name/Initial
Last Name
Deborah
A.
Student's Major
Bidwell
Student's Level
Academic Term
Year
Publication Type
Mathematics
Journal
Deep transcriptomic profiling
reveals sequence diversity
in the hemocyanin IgG-like
domain from the
aquacultured Pacific
whiteleg shrimp,
Litopenaeus vannamei.
Bidwell, Deborah A: bidwelld bidwelld@cofc.edu
Volume
8
Authors
Is a student?
Institution of contributor, CWID
if not College of
Charleston
Is Student Earning Course Associated Course Prefix Associated Course
Credit?
Number
Is a student?
if not College of
Charleston
Credit?
Number
User
Email
Burnett, Karen G: burnettk
burnettk@cofc.edu
Department/Program
(Most Recent)
Biology
Volume
Issue Number
of Pages
Middle Name/Initial
Last Name
Publisher
Authors
First Name
Report Generated on Aug 12, 2015 at 01:23:09 PM CDT
Is a student?
if not College of
Page 1 of 181
Charleston
J.L.
Student's Major
Johnson
Student's Level
Academic Term
Year
Middle Name/Initial
Last Name
Student's Major
Kniffin
Student's Level
Academic Term
Year
First Name
Middle Name/Initial
Last Name
Louis
E.
Student's Major
Burnett
Student's Level
Academic Term
Year
Middle Name/Initial
Last Name
Student's Major
Anderson
Student's Level
Academic Term
Year
First Name
Middle Name/Initial
Last Name
Karen
Gray
Student's Major
Burnett
Student's Level
Academic Term
Year
Department/Program
(Most Recent)
Biology
Publication Type
Mathematics
Journal
Effects of environmental
Integrative and Comparative
hypoxia and elevated CO2 Biology
on the hemocyanin oxygen
binding properties of the
Atlantic mud crab,
Panopeus herbstii
First Name
C.D.
First Name
P.E.
User
Email
burnettk@cofc.edu
Credit?
Number
Is a student?
if not College of
Charleston
Credit?
Number
Is a student?
if not College of
Charleston
Credit?
Number
Is a student?
if not College of
Charleston
Credit?
Number
Is a student?
if not College of
Charleston
Credit?
Number
Publisher
Page 2 of 181
Volume
Issue Number
of Pages
Middle Name/Initial
Last Name
Student's Major
Millan-Hernandez
Student's Level
Academic Term
Year
First Name
Middle Name/Initial
Last Name
Karen
Gray
Student's Major
Burnett
Student's Level
Academic Term
Year
First Name
Middle Name/Initial
Last Name
Louis
E.
Student's Major
Burnett
Student's Level
Academic Term
Year
Publication Type
Publisher
Mathematics
Journal
Recovery from hypoxia and
hypercapnic hypoxia:
Impacts on the transcription
of key antioxidants in the
shrimp Litopenaeus
vannamei
Comparative Biochemistry
and Physiology Part B:
Biochemistry and Molecular
Biology
Authors
First Name
C
Is a student?
Credit?
Number
Is a student?
if not College of
Charleston
Credit?
Number
Is a student?
if not College of
Charleston
Credit?
Number
User
Email
burnettk@cofc.edu
Department/Program
(Most Recent)
Biology
Volume
Issue Number
of Pages
43-49
2014
First Name
Middle Name/Initial
Last Name
C.
D.
Kniffin
170
if not College of
Charleston
Authors
Is a student?
if not College of
Charleston
Page 3 of 181
Student's Major
Student's Level
Credit?
Number
Academic Term
Year
First Name
Middle Name/Initial
Last Name
Louis
E.
Student's Major
Burnett
Student's Level
Academic Term
Year
First Name
Middle Name/Initial
Last Name
Karen
Gray
Student's Major
Burnett
Student's Level
Academic Term
Year
Publication Type
Mathematics
Journal
Deep transcriptomic profiling
reveals sequence diversity
in the hemocyanin IgG-like
domain from the
aquacultured Pacific
whiteleg shrimp,
Litopenaeus vannamei.
Is a student?
if not College of
Charleston
Credit?
Number
Is a student?
if not College of
Charleston
Credit?
Number
User
Email
Burnett, Louis E: burnettl
burnettl@cofc.edu
Department/Program
(Most Recent)
Biology
Volume
Issue Number
of Pages
Middle Name/Initial
Last Name
Student's Major
Johnson
Student's Level
Academic Term
Year
Middle Name/Initial
Last Name
Publisher
Authors
First Name
J.L.
First Name
C.D.
Is a student?
if not College of
Charleston
Credit?
Number
Is a student?
if not College of
Charleston
Kniffin
Page 4 of 181
Student's Major
Student's Level
Academic Term
Year
First Name
Middle Name/Initial
Last Name
Louis
E.
Student's Major
Burnett
Student's Level
Academic Term
Year
Middle Name/Initial
Last Name
Student's Major
Anderson
Student's Level
Academic Term
Year
First Name
Middle Name/Initial
Last Name
Karen
Gray
Student's Major
Burnett
Student's Level
Academic Term
Year
Publication Type
Mathematics
Journal
Effects of environmental
Integrative and Comparative
hypoxia and elevated CO2 Biology
on the hemocyanin oxygen
binding properties of the
Atlantic mud crab,
Panopeus herbstii
First Name
P.E.
Credit?
Number
Is a student?
if not College of
Charleston
Credit?
Number
Is a student?
if not College of
Charleston
Credit?
Number
Is a student?
if not College of
Charleston
Credit?
Number
User
Email
burnettl@cofc.edu
Department/Program
(Most Recent)
Biology
Publisher
Volume
Issue Number
of Pages
Middle Name/Initial
Last Name
Is a student?
Student's Major
Millan-Hernandez
Student's Level
Authors
First Name
C
if not College of
Charleston
Page 5 of 181
Credit?
Number
Academic Term
Year
First Name
Middle Name/Initial
Last Name
Karen
Gray
Student's Major
Burnett
Student's Level
Academic Term
Year
First Name
Middle Name/Initial
Last Name
Louis
E.
Student's Major
Burnett
Student's Level
Academic Term
Year
Publication Type
Mathematics
Journal
Interactive effects of
Archives of Environmental
mosquito control insecticide Contamination and
Toxicology
toxicity, hypoxia, and
increased carbon dioxide on
larval and juvenile Eastern
oysters and hard clams
Is a student?
Credit?
Number
Is a student?
if not College of
Charleston
Credit?
Number
User
Email
burnettl@cofc.edu
Department/Program
(Most Recent)
Biology
Volume
Issue Number
of Pages
450-462
2014
Middle Name/Initial
Last Name
Student's Major
Garcia
Student's Level
Academic Term
Year
Middle Name/Initial
Last Name
Student's Major
Chung
Student's Level
66
if not College of
Charleston
Publisher
Authors
First Name
R.N.
First Name
K.W.
Is a student?
if not College of
Charleston
Credit?
Number
Is a student?
if not College of
Charleston
Credit?
Number
Page 6 of 181
Academic Term
Year
Middle Name/Initial
Last Name
Student's Major
Key
Student's Level
Academic Term
Year
First Name
Middle Name/Initial
Last Name
Louis
E.
Student's Major
Burnett
Student's Level
Academic Term
Year
Middle Name/Initial
Last Name
Student's Major
Coen
Student's Level
Academic Term
Year
First Name
Middle Name/Initial
Last Name
M.
E.
Student's Major
DeLorenzo
Student's Level
Academic Term
Year
Publication Type
Publisher
Mathematics
Journal
Recovery from hypoxia and
hypercapnic hypoxia:
Impacts on the transcription
of key antioxidants in the
shrimp Litopenaeus
vannamei
Comparative Biochemistry
and Physiology Part B:
Biochemistry and Molecular
Biology
of Pages
43-49
2014
First Name
P.B.
First Name
L.
User
Email
burnettl@cofc.edu
Department/Program
(Most Recent)
Biology
Volume
Issue Number
170
Is a student?
if not College of
Charleston
Credit?
Number
Is a student?
if not College of
Charleston
Credit?
Number
Is a student?
if not College of
Charleston
Credit?
Number
Is a student?
if not College of
Charleston
Credit?
Number
Page 7 of 181
Authors
User
First Name
Middle Name/Initial
Last Name
C.
D.
Student's Major
Kniffin
Student's Level
Academic Term
Year
First Name
Middle Name/Initial
Last Name
Louis
E.
Student's Major
Burnett
Student's Level
Academic Term
Year
First Name
Middle Name/Initial
Last Name
Karen
Gray
Student's Major
Burnett
Student's Level
Academic Term
Year
Department/Program
(Most Recent)
Biology
Publication Type
Mathematics
Journal
Characterization of circadian
behavior in the starlet sea
anemone, Nematostella
vectensis.
Issue Number
of Pages
First Name
Middle Name/Initial
Last Name
William
D
Student's Major
Hendricks
Student's Level
Academic Term
Year
Middle Name/Initial
Last Name
Email
Byrum, Christine A: byrumc byrumc@cofc.edu
Volume
Is a student?
if not College of
Charleston
Credit?
Number
Is a student?
if not College of
Charleston
Credit?
Number
Is a student?
if not College of
Charleston
Credit?
Number
Publisher
Authors
First Name
Is a student?
if not College of
Charleston
Credit?
Number
Is a student?
if not College of
Page 8 of 181
Charleston
Christine
A
Student's Major
Byrum
Student's Level
Academic Term
Year
First Name
Middle Name/Initial
Last Name
Elizabeth
L.
Student's Major
Meyer-Bernstein
Student's Level
Academic Term
Year
Publication Type
Mathematics
Journal
Pathology and impact of the Diseases of Aquatic
Organisms
invasive nematode,
Anguillicoloides crassus on
the American eel, Anguilla
rostrata
Credit?
Number
Is a student?
if not College of
Charleston
Credit?
Number
User
Email
de Buron, Isaure: deburoni
deburoni@cofc.edu
Department/Program
(Most Recent)
Biology
Volume
Issue Number
of Pages
Middle Name/Initial
Last Name
Student's Major
Hein
Student's Level
Academic Term
Year
First Name
Middle Name/Initial
Last Name
W
A
Student's Major
Roumillat
Student's Level
Academic Term
Year
Middle Name/Initial
Last Name
Publisher
Authors
First Name
J.
First Name
S
Is a student?
if not College of
Charleston
Credit?
Number
Is a student?
if not College of
Charleston
Credit?
Number
Is a student?
if not College of
Charleston
Arnott
Page 9 of 181
First Name
Student's Major
Student's Level
Academic Term
Year
Middle Name/Initial
Last Name
Student's Major
de Buron
Student's Level
Academic Term
Year
Publication Type
Mathematics
Journal
Population dynamics of
endoparasites of the spotted
seatrout in South Carolina
estuaries
Isaure
Credit?
Number
Is a student?
if not College of
Charleston
Credit?
Number
User
Email
deburoni@cofc.edu
Department/Program
(Most Recent)
Biology
Volume
Issue Number
of Pages
Middle Name/Initial
Last Name
Student's Major
Arnott
Student's Level
Academic Term
Year
Middle Name/Initial
Last Name
Student's Major
Dykova
Student's Level
Academic Term
Year
First Name
Middle Name/Initial
Last Name
William
A
Student's Major
Roumillat
Student's Level
Publisher
Authors
First Name
Steve
First Name
Iva
Is a student?
if not College of
Charleston
Credit?
Number
Is a student?
if not College of
Charleston
Credit?
Number
Is a student?
if not College of
Charleston
Credit?
Number
Page 10 of 181
First Name
Academic Term
Year
Middle Name/Initial
Last Name
Student's Major
de Buron
Student's Level
Academic Term
Year
Publication Type
Mathematics
Journal
Comparative Parasitology
New host record
(Gobiosoma bosc,
Teleostei), for
Homalometron sp.
(Digenea: Apocreadiidae) in
Charleston Harbor, South
Carolina, U.S.A
Isaure
Is a student?
if not College of
Charleston
Credit?
Number
User
Email
deburoni@cofc.edu
Department/Program
(Most Recent)
Biology
Volume
Issue Number
of Pages
2015
Middle Name/Initial
Last Name
Student's Major
D'Aguillo
Student's Level
Academic Term
Year
Middle Name/Initial
Last Name
Student's Major
Sotka
Student's Level
Academic Term
Year
Middle Name/Initial
Last Name
Student's Major
de Buron
Student's Level
Publisher
Authors
First Name
Michelle
First Name
Erik
First Name
Isaure
Is a student?
if not College of
Charleston
Credit?
Number
Is a student?
if not College of
Charleston
Credit?
Number
Is a student?
if not College of
Charleston
Credit?
Number
Page 11 of 181
Academic Term
Year
Publication Type
Mathematics
Journal
Parasitology Research
The muscle dwelling
myxozoan, Kudoa inornata,
enhances swimming
performance in the spotted
seatrout, Cynoscion
nebulosus
User
Email
deburoni@cofc.edu
Department/Program
(Most Recent)
Biology
Publisher
Volume
Issue Number
of Pages
2015
First Name
Middle Name/Initial
Last Name
Eric
J
Student's Major
McElroy
Student's Level
Academic Term
Year
Middle Name/Initial
Last Name
Student's Major
George
Student's Level
Academic Term
Year
Middle Name/Initial
Last Name
Student's Major
de Buron
Student's Level
Academic Term
Year
Department/Program
(Most Recent)
Biology
Publication Type
Mathematics
Journal
Striped Bass, Morone
saxatilis, identified as new
host for a parasite of public
health concern in Striped
Bass, Morone saxatilis,
Authors
First Name
Andrew
First Name
Isaure
User
Email
deburoni@cofc.edu
Is a student?
if not College of
Charleston
Credit?
Number
Is a student?
if not College of
Charleston
Credit?
Number
Is a student?
if not College of
Charleston
Credit?
Number
Publisher
Page 12 of 181
identified as new
host for a parasite of public
health concern in South
Carolina
Volume
Issue Number
of Pages
Middle Name/Initial
Last Name
Student's Major
Taliercio
Student's Level
Academic Term
Year
Middle Name/Initial
Last Name
Student's Major
Darden
Student's Level
Academic Term
Year
First Name
Middle Name/Initial
Last Name
Vincent
A
Student's Major
Connors
Student's Level
Academic Term
Year
First Name
Middle Name/Initial
Last Name
William
A
Student's Major
Roumillat
Student's Level
Academic Term
Year
Middle Name/Initial
Last Name
Student's Major
de Buron
Student's Level
1
Authors
First Name
Michelle
First Name
Tanya
First Name
Isaure
Is a student?
if not College of
Charleston
Credit?
Number
Is a student?
if not College of
Charleston
Credit?
Number
Is a student?
if not College of
Charleston
Credit?
Number
Is a student?
if not College of
Charleston
Credit?
Number
Is a student?
if not College of
Charleston
Credit?
Number
Page 13 of 181
Academic Term
Year
Publication Type
Mathematics
Journal
Infection of newly recruited ICES Journal of Marine
Sciences
American eels (Anguilla
rostrata) by the invasive
swimbladder parasite
Anguillicoloides crassus in a
U.S. Atlantic tidal creek
User
Email
deburoni@cofc.edu
Department/Program
(Most Recent)
Biology
Volume
Issue Number
of Pages
2015
Middle Name/Initial
Last Name
Student's Major
Hein
Student's Level
Academic Term
Year
Middle Name/Initial
Last Name
Student's Major
de Buron
Student's Level
Academic Term
Year
Middle Name/Initial
Last Name
Student's Major
Roumillat
Student's Level
Academic Term
Year
Middle Name/Initial
Last Name
Student's Major
Post
Student's Level
Academic Term
Year
Publisher
Authors
First Name
Jennifer
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Cryptic phenotypic plasticity Zoological Studies
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Sensory system plasticity
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Sex and weapons:
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Host performance as a
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Exploring the spatially
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The American Naturalist
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BMC evolutionary biology
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Rhinobatos whitei, a new
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Olive ridley sea turtle
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nest sand at Ostional, Costa
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Redefining fine roots
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2015
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nitrogen reflect alternate soil
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The rhizosphere and
hyphosphere differ in their
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Improved scaling of
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941-948
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Long-term dynamics of
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loblolly pine forest grown
with free-air-CO2enrichment and soil N
fertilization for 6 years
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Root length, biomass, tissue
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temperate forest
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Swimming performance of Journal of Fish Biology
Fundulus majalis and
Fundulus heteroclitus under
different salinity regimes.
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8
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Natural history of Spain:
teaching students about
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Journal of Natural History
and Experience
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New host record
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Teleostei), for
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2015
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Changes in root architecture
under elevated
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nitrogen reflect alternate soil
exploration strategies.
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Mathematics
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an empiricallyderived depth of field and
correcting for the
underestimation of root
diameters
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Long-term dynamics of
mycorrhizal root tips in a
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loblolly pine forest grown
with free-air-CO2enrichment and soil N
fertilization for 6 years
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Root length, biomass, tissue
chemistry and mycorrhizal
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years of CO2 enrichment
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fertilization in a warm
temperate forest
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compartmentalization
underlies stimulus specific
adaptation in an insect
neuron
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Journal Article, Professional Mechanical properties of the PeerJ
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cuticles of three cockroach
species that differ in their
wind-evoked escape
behavior.
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Mathematics
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Jeffrey
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filiform receptor neuron
afferents of the windsensitive cercal system in
three cockroach species.
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Journal of Insect Physiology
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Hovering Flight in the
Honeybee Apis mellifera:
Kinematic Mechanisms for
Varying Aerodynamic
Forces
Physiological and
Biochemical Zoology
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Jeffrey
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PREVALENCE OF
BATRACHOCHYTRIUM
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DENDROBATIDIS IN
AGALYCHNIS MORELETII
(HYLIDAE) OF EL
SALVADOR AND
ASSOCIATION WITH
LARVAL JAW SHEATH
DEPIGMENTATION
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47
3
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Yang, Lei: yangl
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Mathematics
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A description of the
mitogenome of the
Endangered Taiwanese
angelshark, Squatina
formosa.
Mitochondrial DNA
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Date Range: Jul 01, 2014 - Jun 30, 2015
Department/Program: Chemistry & Biochemistry
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Silane: A Combined
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Characterization of new and
some known organic
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carbazate and its
119
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transformation into
hydrazones
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Preparation of 2Hspiro[Benzo[d]isothiazole3,3'-pyrazole]-1,1-dioxide2'(4'H)-carboxylates from
Dilithiated C( ),NCarboalkoxyhydrazones and
Methyl 2(Aminosulfonyl)benzoate
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Hydrazine
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methyl 2-acetyl-5'-(2-thienyl2H-spiro[benzo[d]isothiazole-3,3'-pyrazole]1,1-dioxide-2'(4'H)carboxylate and methyl 2acetyl-5'-phenyl-2Hspiro[benzo[d]-isothiazole3,3'-pyrazole]-1,1-dioxide2'(4'H)-carboxylate
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The synthesis and crystal
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ne)-hydrazinecarboxylate
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drazinecarboxylate
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Preparation of FerrocenylPyrazoles from Dilithiated
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Part B: Polymer Physics
Assembly of Poly-(3hexylthiophene) Using
Solubility and
Solvatochromic Parameters
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Persistent
Phototransformation
Products of Vardenafil
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Chemosphere
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2015
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Influence of Organic Matter Environmental Pollution
on Sorption and
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of Naproxen and Ibuprofen
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Collard Landraces are
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Glucoraphanin and other
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Plant Breeding
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Tightening of Active Site
Interactions En-route to the
Transition State Revealed
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Group I Ribozyme
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adopted by Peptidomimetics
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to Acetylcholinesterase
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PREVALENCE OF
BATRACHOCHYTRIUM
DENDROBATIDIS IN
AGALYCHNIS MORELETII
(HYLIDAE) OF EL
SALVADOR AND
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PROMS101
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LARVAL JAW SHEATH
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American Heart Association
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On Asymptotic behavior of
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Evolution of communication MIT Press
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Heteroscedastic model via
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Decompositions of λKn
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185-195
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New Construction
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LambdaK_n into multigraphs
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30
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The p-adic Arakawa-Kaneko Journal of Number Theory
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Spitzer: deep observations
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Journal Article, Professional The outer disks of Herbig
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Journal Article, Professional The Structure of PreJournal
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Journal Article, Professional The VLT/NaCo large
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Journal Article, Professional SPOTS: The Search for
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Planets Orbiting Two Stars I.
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Journal Article, Professional Near-infrared polarimetry of
Journal
the GG Tauri A binary
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1438
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Itoh
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Journal Article, Professional Surface Geometry of
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Protoplanetary Disks
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A Statistical
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Analysis of SEEDS and
Other High-contrast
Exoplanet Surveys: Massive
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Dwarfs?
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Probing for
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Exoplanets Hiding in Dusty
Debris Disks: Disk Imaging,
Characterization, and
Exploration with HST/STIS
Multi-roll Coronagraphy
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Journal Article, Professional The Structure of HE 1104- Institute of Physics (IOP)
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Local Stability of Strongly
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The X-Ray Flux Distribution The Astrophysical Journal
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Mathematics
Journal
No Evidence for Bardeen- The Astrophysical Journal
Petterson Alignment in
GRMHD Simulations and
Semi-Analytic Models of
Moderately Thin, Prograde,
Tilted Accretion Disks
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104
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The Astrophysical Journal
Conservative GRMHD
Simulations of Moderately
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103
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Radio and Millimeter
Monitoring of Sgr A*:
Constraints on the G2
Encounter and the Spectrum
and Variability of Sgr A*
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Mathematics
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Numerical Simulations of
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Rotating Flow
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Moon and Europa Missions
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Mathematics
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Estimates of the Statistical
Two-Dimensional Spatial
Structure in Rain over a
Small Network of
Disdrometers
Springer
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Jameson
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Larsen, Michael L: larsenml larsenml@cofc.edu
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On the Variability of Drop
Size Distributions over
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72
4
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1386--1397
2015
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Disdrometer network
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observations of fine scale
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rain
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72
4
of Pages
1648--1666
2015
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Charleston
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Jameson
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Michael
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Identifying Individual Rain
Events with a Dense
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12 pages
2015
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Michael
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Larsen
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of Pages
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Mathematics
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Elsevier
Scaling properties of
raindrop size distributions as
measured by a dense array
of optical disdromters
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424--432
2015
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Larsen
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521
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Timothy
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Teves
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On the recovery of 3D
spatial statistics of particles Society
from 1D measurements:
Implications for Airborne
Instruments
Volume
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31
10
of Pages
2078--2087
2014
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Michael
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Larsen
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Briner
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Boehner
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Philip
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Further evidence for super- American Geophysical
terminal raindrops
Union
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of Pages
2014
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Dimple coalescence and
Eur. Phys. Journal E Soft.
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Mathematics
Journal
Volume
Issue Number
37
9
of Pages
41
2014
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Oprisan
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liquid droplets distributions Matter
during phase separation in a
pure fluid under microgravity
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Ana
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Sorinel
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90
022127
Journal Article, Professional Imaging critical fluctuations Physical Review E
Journal
of pure fluids and binary
mixtures
of Pages
8 pages
2014
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Mathematics
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Beysens
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Dimple coalescence and
Eur. Phys. Journal E Soft.
liquid droplets distributions Matter
during phase separation in a
pure fluid under microgravity
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Oprisan, Sorinel: oprisans
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37
9
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41
2014
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Oprisan
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Journal
Photometric and
Astrophysical
Spectroscopic Studies of
Journal/American
Astronomical Society
Massive Binaries in the
Large Magellanic Cloud. II.
Three O-type Systems in the
30 Dor Region
Yves
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Daniel
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Penny, Laura R: pennyl
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2014
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Morrell
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Neugent
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Penny
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Gies
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Mathematics
Journal
Applications of Acoustic
Bragg Imaging in BioMaterials
Journal of the Acoustcial
Society of America
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Kathryn
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Douglas
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Teklu, Alem A: teklua
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Alem
Abraha
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McPherson
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Mathematics
Journal
The Effects of Vortex
Structure and Vortex
Translation on the Tropical
Cyclone Boundary Layer
Wind Field
Journal of Advances in
Modeling Earth Systems
Michael
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Williams, Gabriel J:
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7
1
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188-214
2015
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Diversity Report
June 22, 2015
The following diversity activities took place in the School of Sciences and Mathematics since July 2014.
Summer 2014
 In Summer II, Dr. Dawne Taylor offered a section of CHEM 103, a preparatory class for general
chemistry, for 12 entering SCAMP/SPECTRA students. These URM students all enrolled in
CHEM 103 and MATH 111 with Dr. Sophia Agrest.

Both the Howard Hughes Medical Institute (HHMI) and NIH-INBRE grants on campus have
incentivized and continue to incentivize faculty to seek URM students to participate in their
research group by providing stipends and supply money for students

The Engaging Creative Minds Summer STEAM Institute was held for creative and energetic
students in grades 3-8. They spent their summer engaged in unique learning experiences that
fostered creativity to solve real world challenges working with local artists, cultural organizations,
and professionals in the fields of science, technology, engineering, and mathematics. At least
25% of the students were from title 1 school. STEAM has an added component (A for ARTS)
from a traditional STEM program.
Fall Semester 2014



The SCAMP Program provides URM students with opportunities to challenge themselves
academically, to increase their chances for academic success, to prepare them for what to expect
in STEM career fields, and to sharpen their academic skills.
BIOL associate professor Chris Korey taught a Learning Community First Year Experience for
SCAMP students.

Community Outreach Research and Learning (CORAL) The Grice Marine Lab held numerous
discussions, demonstrations, and hands-on activities for pre-college students, especially URM
students.

The Tensor SUMMA Grant was awarded to Dr. Sophia Agrest (MATH) to encourage the pursuit
and enjoyment of mathematics by students who are members of groups historically
underrepresented in the field of mathematics.

A follow-up fall break The Frog Scientist workshop was held for 5th and 6th graders from
Memminger, Mitchell, and James Simons Elementary Schools.

The College of Charleston has been selected to participate in the renewal of the statewide NIHINBRE grant which has a major component of interfacing with the SCAMP program. Faculty
members in the biomedical research field are currently to become Target Faculty through its
Developmental Research Project Program. The current grant finishes up this summer and is
sponsoring

On October 1 the SCAMP program held its annual research dinner featuring research
presentations by undergraduate students.

On October 8 the Gender and Sexual Equity Center held a forum on “Women in Science” as part
of the Diversity Week celebration. Faculty members from SSM participating were Linda Jones
(PHYS) , Christine Moore (CSCI), Courtney Murren (BIOL), and Ana Zimmerman (BIOL).

Throughout the year PHYS Faculty held presentations on various physics and astronomy topics
including discussions, demonstrations, and hands-on activities for K-12 students, especially URM
students.

Departments have begun faculty recruiting efforts and incorporating tactics to increase the
number of minority applicants.

SSM made a major financial contribution of $7500 to the SCAMP budget.

Diversity is a topic on the agenda at each semi-monthly department chairs meeting.

The Department of Computer Science’s Women in Computing chapter continues to grow in number.

Research Student Outcomes: Fall 2014 HHMI students and others supported in HHMI labs Graduate School in Science Medical/ Dental/ Vet Other Graduate Employed in Science Left Science Unknown Still planning to apply to Med Still planning to apply for Grad Still planning to apply to other grad Graduated Students N=182 Graduated URM students N=18 59 32% 7 39% 33 18% 1 6% 18 10% 1 6% 22
12% 2
11% 7
4% 0
0% 6
3% 1
6% 20
11% 4
22% 11 6% 2 11% 6
3% 0
0% Spring Semester 2015
 The School of Sciences & Mathematics hosted approximately 100 students from Mitchell
Elementary on January 9 and 10, 2014 to participate in a number of hands-on activities in
biology, chemistry, & physics.

The SSM office was joined by URM Maya Dillegard as one of our student workers.

At the STEM Festival Kick-off at Brittlebank Park on Saturday February 7 the Lowcounty Hall of
Science and various SSM faculty members sponsored numerous hands-on activities for the
approximate 3000 participants, over 50% of who were female and around 20% of whom were
underrepresented minorities.

Darwin Week, with a special Piccolo Darwin Week for local K-12 communities, was held in honor
of Charles Darwin’s birthday, February 9-13. During the week, around 200 students attended
lectures on evolutionary science.

On February 13 the second annual Education Day at the College of Charleston Women’s
Basketball game featured S.T.E.M. activities presented by all of the departments of the School of
Sciences & Mathematics, the School of Education, Health & Human Performance, and the Office
of Sustainability, plus several non-CofC agencies. Approximately 1600 4th-8th graders and their
teachers and chaperones attended. Over 40% of those attending were from underserved
communities.

On Saturday, February 14 the Math Department hosted its 39th annual Math Meet.
Approximately 800 students and coaches from the tri-state area come to Charleston for a day of
mathematics competition, culminating in an event hosted by the American Mathematical Society
called "So you want to be a mathematician", and ending in an awards ceremony. The event is a
celebration of exceptional talent and broad diversity. Every race, sex, ethnicity is highly
represented.

On April 24, the Department Physics and Astronomy, the Lowcountry Hall of Sciences &
Mathematics, and the NASA Space Grant hosted an Astronomy Night at the Charleston
Riverdogs game.

The SSM Poster Session on April 17 featured 132 posters, many from SCAMP, HHMI, or INBRE
minority students.

Dr. Wendy CORY (CHEM) received the Outreach Volunteer Award from the South Carolina
Section of the American Chemical Society , much in part to her NSF-sponsored grant activities
that includes an outreach component to URM students at Title I schools.

On May 14, the Department of Chemistry & Biochemistry participated in a STEM hands-on
activity night at Charleston Charter School for Math & Science. Approximately 200 students
participated.

The following Excel awards were presented to members of SSM:
o Pamela Riggs-Gelasco (Chemistry & Biochemistry), SSM Outstanding Faculty Member
o SCAMP Student of the Year - Aliya Dumas (Biology)
o SSM Student of the Year- Quinten Meadors (Biology)
o Honors College Outstanding Student – Neha V. Muoppala (Biology) and Needhee N.
Patel (Biology)
o Eugene C. Hunt Senior Minority Student- Tervor Stubbs-Stroud (Marine Biology)
o Eugene C. Hunt Junior Minority Student- Jasmin R. Graham (Marine Biology)
o Outstanding Female Athlete of the Year – Alexia M. Neal

HHMI and INBRE will be funding a number of minority students to participate in summer research
projects with SSM faculty.

On May 29 three classes of students from Sanders-Clyde Elementary, hosted by CHEM and
GEOL, participated in hands-on chemical activities and toured the Natural History Museum.

The faculty hiring process in the Department of Physics and Astronomy concluded with an offer
being made to a female.

Dr. Mani Pokharel, a URM, has been hired as the Physics laboratory manager.

Dr. Susan Morrison of the Department of Biology is the academic advisor for students
participating in the PREP program for MUSC students. This program is designed to prepare
applicants who are from underrepresented groups in medicine & dentistry and who are
considered to have a good chance of success. They are selected from the pool of applicants to
MUSC’s dental school or medical school. They spend one year at the College of Charleston
taking primarily science courses, with funding coming from MUSC.

Dr. Narayanan Kuthirummal of the Department of Physics and Astronomy mentored is the STEM
advisor to 7 students in the ASCEND (Achievement, Self-awareness, Communication,
Engagement, Networking, and Development Skills) program of the Alpha Kappa Alpha Sorority,
Inc. Students in this program will have an opportunity to receive academic enrichment and life
skills training to support their journey to college or vocational employment.

From 2010‐2013 Chemistry & Biochemistry sent 73% of its URM students (African American and Latino) to graduate and professional schools (MD, PhD, pharmacy, etc.) 
In June 2015 the Department of Computer Science hosted the Geek Squad Summer Academy. The 2‐day computer camp comprises about 100 girls mostly from the Lowcountry. Sponsored by Best Buy Geek Squad, the girls learn subjects such as Robotics, Digital Filming, 3‐D Printing, and Digital Citizenship. SSM ASSESSMENT REPORT FOR THE FY15 ANNUAL REPORT SSM assessed three program goals relating to delivery of general education courses, providing undergraduate
research opportunities, and improving environmental health and safety.
1)
PROGRAM GOAL: To provide students in general education courses with outstanding instruction provided
by roster faculty members in the discipline.
The data below are for General Education lecture courses only. This is not to denigrate the instruction of
laboratories at the introductory level. However, reality dictates that we will never have enough faculty lines to
teach the lab sections. The hope is to be able to cover all the lectures with roster faculty.
Lectures Adjunct Only Sections BIOL Adjunct Roster Students Sections Roster Students 18 977 6 285 CHEM 5 199 10 397 GEOL 2 95 10 664 HONS 0 0 5 140 MATH 13 1390 59 1310 PHYS 2 82 15 526 Total 40 2743 105 3322 Lectures Adjunct Adjunct Only Students Sections Sections Roster Roster Students BIOL 75.0% 77.4% 25.0% 22.6% CHEM 33.3% 33.4% 66.7% 66.6% GEOL 16.7% 12.5% 83.3% 87.5% HONS 0.0% 0.0% 100.0% 100.0% MATH 18.1% 51.5% 81.9% 48.5% PHYS 11.8% 13.5% 88.2% 86.5% 27.6% 45.2% 72.4% 54.8% The table below shows the % adjunct usage over the last 4 fall semesters.
% Adjunct Usage‐ Students Taught‐ Lectures Only 2011 2012 2013
2014
BIOL 68.4% 79.2% 60.1% 77.4% CHEM 36.5% 49.6% 42.9% 33.4% GEOL 19.1% 0.0% 25.0% 12.5% HONS 0.0% 0.0% 0.0% 0.0% MATH 36.2% 27.6% 52.6% 51.5% PHYS 0.0% 0.0% 0.0% 13.5% Overall 38.7% 42.6% 42.9% 45.2% It is very evident that two departments have an extremely high adjunct dependence (BIOL and MATH) and a third,
CHEM, has a very high adjunct dependency.
2)
PROGRAM GOAL: To provide students with a highly personalized education enhanced by opportunities to
perform
SSM STUDENTS PERFORMING UNGERGRADUATE RESEARCH FOR CREDIT Fall 2012 Spring 2013 FY 2013 Fall 2013 Spring 2014 FY 2014 Fall 2014 Spring 2015 FY 2015 BIOL 34 47 81
49
43
92
37 43
80
CHEM 24 25 49
44
26
70
38 43
81
CSCI 6 10 16
10
6
16
4 8
12
GEOL 1 21 22
5
5
10
2 3
5
MATH 1 1 2
3
2
5
0 0
0
PHYS 12 16 28
21
20
41
16 23
39
Total 78 120 198
132
102
234
97 120
217
We are able to provide a large number of our students with opportunities. It is important to track these numbers for reporting to granting agencies.
3)
PROGRAM GOAL: To enhance safety in all laboratory and field experience courses by working with the
respective SSM departments and the office of Environmental Health and Safety to improve and add to
existing policies and procedures.
4)
A committee of SSM lab managers and faculty worked with the Director of Environmental Health & Safety and the
College's Industrial Hygienist/Safety Manager to improve and add to existing policies and procedures. The SSM
Lab Managers Safety Committee met on a regular basis throughout the fall, tackling a number of issues, solving
some, discovering new ones. Challenges involving signage, waste pick-up, and training were addressed. An OSHA
training workshop was held for the lab managers in December. Challenges remain in instituting laboratory
inspections and establishing proper communication channels between stockroom personnel and their department
chairs or facility manager. A meeting with department chairs and the Grice Marine Lab director was held in the
spring to discuss communication issues. Wrestling through the process it was decided to focus on one department,
the one with the most risk exposure, Chemistry and Biochemistry.
APPENDIX E
2014 - 2015 Award Recipients
The office of Undergraduate Research and Creative Activities is pleased to
announce the Grant Award Recipients for 2014–2015 academic year.
Please join us in congratulating these students and their mentors.
Academic Year Research Grant (AYRA)
1.
Student: Sahand Askarian
Major: Biochemistry
Mentor: Gamil Guirgis
Department: Chemistry and Biochemistry
Title: Novel Isocyanation of Chloromethyl Silane
As part of my long-standing research program in chemistry, we prepare, characterize, and predict
the characteristic and spectroscopic properties of small organic compounds. This project was started
as a result of a novel isocyanation mechanism that is not yet explained by the means of organic and
inorganic chemistry. We correlate the theoretical ab initio predictions of molecules to the observed
experimental values. This fundamental area of research may lead to interesting applications and
certainly will lead to publications in a refereed journal. The refinement of fundamental knowledge is a
very appropriate activity in which to involve undergraduate students in research in a meaningful and
productive manner.
2.
Student: Colin Cotter
Major: Chemistry
Mentor: Gamil Guirgis
Title: Believe it or not, not all six membered ring compounds are not in chair conformation:
preparation, characterization, and spectra of cyclo- 1,3,5-trisiloxane
Organo-silane compounds, molecules with both carbon and silicon, have a variety of uses
ranging from making water proof clothing to assisting in making other chemical compounds. This
projects aims to study organa-silane compounds in a ring formation by synthesizing 1,3,5 trioxatrisilanane. This compound has been predicted t o have an extremely unusual shape where the CSi ring in the compound is planar. Normal rings in chemistry almost always form a complex shape
called chair where they atoms are spread out away from each other on different planes as opposed to be
aligned on one. We aim to synthesize 1 ,3,5-trioxatrisilanane and study its structure through Raman and
infrared spectroscopy for this project.
3.
Student: Allen S. Hill
Major: Physics
Mentor: Alem Teklu
Department: Physics and Astronomy
Title: Thin Film Characterization through Resonant Ultrasound Spectroscopy
Resonant Ultrasound Spectroscopy (RUS) is an experimental technique by which fundamental
material properties can be obtained through acoustic probing. Many of the limitations of the RUS
technique deal with the size, shape, and composition of the sample specimens. The samples used in the
current RUS research at the College of Charleston are commonly a few millimeters in diameter. This
particular experiment necessitates the characterization of a material that is on the order of a few hundred
nanometers in thickness. The two overarching goals of this experiment include the adaption of current
techniques so as to allow for the characterization of these materials. The second goal is to utilize this
technique in order to characterize the mechanical properties for a thin film of Zinc Oxide. The vital
component of this process is the construction of a new RUS sample cell – an apparatus wherein small
micrometer sized samples can be mounted and examined. The apparatus utilizes two transducers, one of
which drives the sample through the application of acoustic waves while the other measures the sample's
response. These transducers are to be created with polyvinylidene fluoride (PVDF) strips that are 9
micrometers thick. This piezoelectric film reduces noise and provides for more accurate measurements. The
cell as a whole can be adapted to utilize the Dynamic Resonance Systems (DRS) Modulus 1, which is used
for all other RUS work presently done at the college.
4.
Student: Marino Mugayar-Baldocchi Major: Psychology
Mentor: Daniel Greenberg
Department: Psychology
Anthony Bishara
Title: Anchoring Autobiographical Memories
Autobiographical memories are memories for the events of everyday life. They help provide the
foundation of our identity and serve as a record of what we have done and where (or who) we have been.
Most people report that they can remember back to the age of three or so, but memories from ages three
to five tend to be vague and fragmented. How reliable are these memories, and how vulnerable are they
to distortion and change? In a previous study, we sought to determine whether participants' earliest
memories were susceptible to a subtle manipulation known as the anchoring effect. This effect occurs
when the presentation of a number affects participants’ estimates of a subsequent uncertain quantity. In
this case, we found that participants who received a low anchor (the number 1) reported earlier
memories than those given a high anchor (the number 6). We now hope to replicate the effect and
extend it by examining a broader range of childhood memories. In this way, we hope to understand how
reliable and pervasive the effect really is, and whether it varies with the age of the memory. We
hypothesize that anchoring will affect a range of childhood memories, not just their earlier memories,
but that the effect will be stronger.
5.
Student: Hannah Wilson
Major: Biology
Mentor: Joe Carson
Title: An Innovative System for 3D Clinical Photography
We recently developed a low-cost, user-friendly technique to take a single snapshot image using the
commercially available Lytro camera and convert this image into a full 3D rendering that can be effective
for the diagnostic monitoring of cancer lesions, such a Kaposi’s sarcoma – the leading cancer among men
in Mozambique. By utilizing a relatively low cost (~$300) consumer camera as the technology backbone,
the technique translates to an estimated cost of around 75 cents per diagnosis. This is an extreme benefit
for areas of the world that cannot afford most 3D imaging technology that is available today. In contrast,
for example, the commonly used Magnetic Resonance Imaging (MRI) has a typical cost of >$2,000 per
diagnosis, as well as requiring expert personnel to operate it and substantial infrastructure to support it.
Our technology provides a way for minimally trained personnel to operate it, and the complicated data
processing work can take place at a location away from the resource limited setting, allowing relevant
results to be succinctly summarized and restored to clinicians in the field. To prove the effectiveness of the
technique, we and collaborators successfully carried out a pilot program at Maputo Central Hospital, the
largest public hospital in Mozambique, and showed that effective, single-snapshot, 3D images of Kaposi’s
sarcoma lesions could be obtained bedside by minimally trained personnel. The results are published in the
Journal of Translational Medicine (Baghdadchi et al. 2014).
Major Academic Year Support (MAYS)
1.
Student: Melina Acosta
Major: Psychology
Mentor: Jennifer Wilhelm
Title: Does estrogen mediate axon regeneration after peripheral nerve injury in males?
Thousands of peripheral nerve injuries occur each year. Although nerves in the peripheral
nervous system have the capacity to regenerate, recovery of function is often poor and incomplete
leaving patients with long-term deficits. Previous studies have shown that exercise in the form of
treadmill training causes an enhancement in axon regeneration following peripheral nerve damage that
could improve functional recovery. Interestingly, this exercise induced increase in regeneration occurs in
a sex dependent manner with males and females requiring different forms of treadmill exercise to
achieve maximal regeneration. The mechanisms mediating this sex difference are relatively unknown.
Previous studies have shown that androgens, such as testosterone, can enhance the regeneration of nerve
following a nerve injury. However testosterone can be converted into estrogen; therefore, the
enhancement by testosterone treatment may be due to an increase in estrogen. The present study will
examine the effects of estrogen on axon regeneration in unexercised and treadmill exercised male mice.
The common fibular branch of the sciatic nerve will be cut and repaired. Estrogen-filled or blank
capsules will be implanted subcutaneously in male mice at the time of nerve transection. Three days post
repair mice will be treadmill exercised for two weeks. Two weeks after the initial cut and repair, neurons
whose axons will have regenerated past the original cut sites will be labeled with a retrograde dye. The
number of labeled neurons will be counted to examine the effects of estrogen on axon regeneration. We
hypothesize that estrogen treatment will enhance axon regeneration after peripheral nerve transection
similar to the enhancement found in treadmill exercised mice. The results of these experiments will
provide insight into whether exercise induced increase in axon regeneration is estrogen dependent.
2.
Student: Alana Acuff
Major: Anthropology
Mentors: James Newhard
Department: Classics
Title: The Global Electronic Repository of Aegean Scripts (GERAS): post-processing 3D structured
light scanning imagery
The Global Electronic Repository of Aegean Scripts (GERAS) as an international, multi-year,
interdisciplinary effort to record the extant remains of writing from the Late Bronze Age Aegean. Formed
in 2012, it elected as its initial project to bring the Linear B archives from the Palace of Nestor at Pylos to
full publication and access via traditional print and online media.
Documentation of the archives includes tablet transcriptions, archaeological illustration,
Reflectance Transformation Imagery (RTI), 3D imaging, X-Ray Fluorescence (XRF) data, and
archaeological context of tablet fragments via geographic information systems (GIS). In the summers
of 2013 and 2014, GERAS collected raw image data of approximately 75% of the nearly 1,200 tablets
and sealings from the archive necessary to complete the project.
The College of Charleston serves as the informatics hub of the project, responsible for the
development and maintenance of the GERAS database, user interface, image files (RTI and 3D), and
geospatial component. In the 2014 academic year, students and faculty will be engaged in developing a
prototype online interface, which will include refining the database structure, processing raw 3D
imagery captured in 2013 and 2014 into final products, developing the online presence of GERAS, and
refining the geospatial search capabilities. RTI image processing, tablet transcriptions, and illustrations will
be concurrently undertaken by project members at the Universities of Texas and Toronto.
This proposal specifically applies to the 3D post-processing component of the project, which
will be undertaken by Acuff in collaboration with Newhard and Baxley.
3.
Student: Jami Baxley
Major: Classics
Mentor: James Newhard
Title: The Global Electronic Repository of Aegean Sripts (GERAS): post-processing 3D structured
light scanning imagery and final season assessment
The Global Electronic Repository of Aegean Scripts (GERAS) is an international, multi-year,
interdisciplinary effort to record the extant remains of writing from the Late Bronze Age Aegean. Formed in
2012, it elected as its initial project to bring the Linear B archives from the Palace of Nestor at Pylos to full
publication and access via traditional print and online media.
Documentation of the archives includes tablet transcriptions, archaeological illustration,
Reflectance Transformation Imagery (RTI), 3D imaging, X-Ray Fluorescence (XRF) data, and
archaeological context of tablet fragments via geographic information systems (GIS). In the summers of
2013 and 2014, GERAS collected raw image data of approximately 75% of the nearly 1,200 tablets
and sealings from the archive necessary to complete the project.
The College of Charleston serves as the informatics hub of the project, responsible for the
development and maintenance of the GERAS database, user interface, image files (RTI and 3D), and
geospatial component. In the 2014 academic year, students and faculty will be engaged in developing a
prototype online interface, which will include refining the database structure, processing raw 3D
imagery captured in 2013 and 2014 into final products, developing the online presence of GERAS, and
refining the geospatial search capabilities. RTI image processing, tablet transcriptions, and illustrations
will be concurrently undertaken by project members at the Universities of Texas and Toronto.
This proposal specifically applies to the 3D imagery post-processing component of the project,
which will be undertaken by Baxley along with Newhard and Alana Acuff.
4.
Student: Aubrey Butcher
Major: Marine Biology
Mentor: Craig Plante
Department: Biology
Title: Effects of Beach Renourishment on Benthic Microalgal Communities
Beaches are valuable resources providing recreational activities and storm protection, and sustaining
diverse biological populations. One method of preserving beaches against the effects of erosion and sea-level
rise is beach renourishment. Folly Beach completed a renourishment project from January-June 2014 and
Tybee Island will begin their own project in November, 2014. Both projects involve transporting (via
pipeline) sediment from offshore borrow sites onto the beach face in hopes of reversing erosional losses;
however, other components of the ecosystem are affected as well.
This study aims to monitor renourishment effects on benthic microalgae (BMA), a group of
photosynthetic microbes found in coastal sediments. BMA, as primary producers, represent the basis of
nearshore food webs. They also release extracellular polymeric secretions (EPS), which bind together
sediment particles thereby inhibiting erosion and sediment transport. Despite these vital roles, few studies
have examined the effects of renourishment on these microbes. By studying BMA biomass, composition,
and EPS, this project will reveal the effects of specific renourishment practices (e.g., use of coarse borrow
sediments) on benthic microalgae. Our research this past summer demonstrated that beach renourishment
does significantly reduce BMA abundance immediately after the event. We also know that BMA recovery
time is longer than 4 months, which is surprising given their motility and short generation times. More
research is needed to understand the differences in BMA species composition between renourished and
control beaches. Findings could lead to changes in renourishment protocols that favor BMA communities,
thereby indirectly enhancing stabilization of newly added beach sands.
5.
Student: Haley Cabaniss
Major: Geology
Mentor: John Chadwick
Department: Geology
Title: Prediction of Catastrophic Eruptions of Colima Volcano, Mexico, via Analyses
of Long-term Trends in Lava Chemistry
Volcan de Colima in western Mexico is one of the most active volcanoes in the world,
erupting dozens of times in the past century. It is therefore an excellent laboratory for
understanding temporal patterns of eruption activity and investigating how eruption magnitudes may
relate to the varying chemistry of its erupted lavas and gases over t i m e . Identifying a relationship between
lava chemistry and eruption activity may allow for improved predictions of t h e particularly powerful and
deadly eruptions that occur at Colima about once every century. This study will focus on the
relationship between the chemical compositions of volatiles (gases such as water vapor and sulfur
dioxide) released before, during, and after volcanic eruptions and those same volatiles trapped in tiny
inclusions within the erupted lava itself. Since volatiles in volcanic systems are the most important drivers
of eruptions, understanding their behavior during the period leading up to and during eruptions may
allow for an improved method of predicting them. Working with a professional colleague in Mexico,
student Haley Cabaniss collected lava samples at Colima during the summer of 2014 from several
eruptions with known dates back to the 1960s. In this study, Haley and her College of Charleston
mentor Dr. John Chadwick will analyze the chemistry of Colima lavas and the volatile gases trapped in
them in an effort to identify temporal patterns in volatile behavior that signal impending larger
eruptions. The project will provide the student with a wealth of field, laboratory, data analysis, and
presentation experience.
6.
Student: Kellen Lawson
Major: Astrophysics
Mentor: Joe Carson
Title: Searching for Extrasolar Planets with the Subaru SEEDS Survey
The Strategic Exploration of Exoplanets and Disks with Subaru (SEEDS) survey is a five year
international astronomical survey with 120 nights of observations using the Subaru telescope atop Mauna
Kea in Hawaii (Tamura et al. 2009). The intent of this survey is to directly image exoplanets and disks (the
reservoirs of material around young stars from which these planets form) around stars and to better
understand how they form and are related.
More specifically, our research comprises a group within SEEDS that focuses on extrasolar planets
around high mass stars. The importance of these stars lies in the fact that they often produce higher mass
planets. Such planets retain more heat and are therefore more visible in infrared wavelengths in which we
observe (Baraffe et al. 2003). Additionally, we will prioritize targeting the youngest stars in this category,
for similar reasons to those above; namely, these systems will have more residual heat, again making
planets more visible in the infrared.
Alternative indirect detection strategies discover planets by observing their effects on the star,
such as a slight drop in stellar brightness due to a transiting planet. Besides revealing the fact that the
planet exists and offering basic limits on planet mass and orbit, these approaches are limited in the
knowledge they provide. With the light from direct imaging, we can produce information on the planet's
temperature, composition, and atmospheric chemistry. While technically difficult, this method allows us
unique insights into characterizing planets and the parameters that affect their formations.
7.
Student: Lawson Lloyd
Major: Biochemistry
Mentor: David Boucher
Title: Atomic Force Microscopy Study of Polymer Films Processed from Mixtures of Organic Solvents
Functional materials that incorporate semiconducting polymers, which are now being used in
solar cells and other optoelectronic devices, are processed by forming a thin film of a polymer solution
onto an appropriate substrate, e.g., glass, quartz, etc. The random nature of the molecular packing of a
polymer during this process is detrimental to the properties of functional composites, and has proved to
be one of the main barriers to achieving high performance devices using polymer materials. In order to
make these materials more efficient we need to control how the polymers organize themselves when the
films are made. Our research group is trying to achieve control by using mixtures of organic solvents,
wherein the disparate properties of the solvents in the mixtures, e.g., evaporation rates and viscosity,
help the polymer assembly in different ways. Using over 100 different solvent mixtures, we have already
shown that we can achieve control of polymer organization in the liquid phase, but now we need to
see what happens when we actually make films from these mixtures. To accomplish this task we will
use atomic force microscopy (AFM) to study the films that we make. AFM is a highly sensitive imaging
technique that allows us to see the structure of polymer films on a molecular, or even an atomic, level.
The high resolution possible with AFM will allow us to observe different film structures with a great
level of detail that can then be tested as possible candidates for solar cells materials.
8.
Student: Kaitlyn Manley
Mentor: Amy Langville
Title: Calculus Workbook Series
Major: Applied Mathematics
Department: Mathematics
This continuing project aims to complete a series of calculus workbooks/journals for publication,
aimed towards secondary and post-secondary students. We will be attempting to overcome challenges faced
by educators in our field: Why are so many students turned off by math? How can we make it appealing and
relatable? What are some successful strategies in engaging students with calculus? These books approach
calculus from a new angle, providing a balanced development of concept- and calculation-based
understanding. Inspired by Keri Smith’s Wreck This Journal series, we invoke creativity as the primary
vehicle for instruction by appealing to kinesthetic learners and those who consider themselves as “nonmath-minded.” Through student involvement and innovative designs, including physical activities, games,
and graphic novellas, we intend to engage the students who are most commonly disconnected from this
surprisingly lively and relatable subject. Highly illustrative, with a focus on visual cues and tactile
involvement, these books can appeal to all students, regardless of prior mathematical interest. In order to
accomplish this, we first intend to research design and educational strategies, existing and comparable texts,
and other sources for creative inspiration. We will then test the books in at least two classes of business
calculus and use the students’ feedback to improve upon their design. Finally, we will promote the series
through academic connections made through conferences and other disseminations of our work. As two
aspiring educators, we will get a hands-on experience of publishing an educational text by the completion of
this project.
9.
Student: Sean Mueller
Major: Studio Art (Sculpture)
Mentor: Jarod Charzewski
Department: Studio Art (Sculpture)
Title: Exploration of the Unifying Factors behind Community, Industry, and Growth through
Sculpture Collaboration in the Landscaped Environment for Art
Sean Mueller and Jarod Charzewski will construct a series of three to five pieces with the intention
of placing them on public display and entering into various sculpture competitions and exhibitions. Sean
and Jarod will explore what elements unify communities and industry, particularly during periods of
growth. They will then express these elements in a series of sculptures for public display in the landscaped
built environment, specifically the sculpture park. The sculptures will be completed by working together:
developing designs, procuring materials, and creating the piece. The project accomplishes both Sean and
Jarod’s goals of academic and career advancement, as well as having the opportunity of working
collaboratively. Sean and Jarod predict the pieces will be installed in public exhibitions and receive high
commendation in competitions.
10.
Student: Joye Nettles
Major: Computer Science
Mentor: James Bowring
Department: Computer Science
Title: CHRONI – An Android Application for geochronologists to access archived sample analyses
from the NSF-funded GeoChron.org data repository
NSF requires data management plan s as part of funding proposals and geochronologists,
among other scientists, are archiving their data and results to the public cloud archives managed by
the NSF-funded Integrated E ar th Data Applications, or IEDA. GeoChron is a database for
geochronology housed within IEDA. The software application U-Pb_Redux[l,2,3] developed by Dr.
Bowring at the College of Charleston provides seamless connectivity to GeoChron for geochronologists
to automatically upload and retrieve their data and results. CHRONI i s a lightweight mobile
application for Android devices that provides easy access to these archived data and results. With
CHRONI, geochronologists can view archived data and analyses downloaded from the GeoChron
database, or any other location, in a customizable format. CHRONI use s special documents called
Report Settings that can be customized in U-Pb_Redux, stored in the cloud, and then accessed and
used in CHRONI to create the customized data display on a mobile device. In addition to providing
geologists effortless mobile access to archived data and analyses, CHRONI allows users to manage their
GeoChron credentials, quickly download private and public files, and view specialized graphics
associated with particular files. Future versions of CHRONI will be developed to support iDScompatible (iPhone, iPod, and iPad) devices. CHRONI is an open source project hosted at
https://github.com/CIRDLES/CHRONI.
11.
Student: Alexis Payne
Major: Physics
Mentor: Alem Teklu
Mike Larson
Title: Resolving Airborne Particulate Concentration Inhomogeneities with a Schlieren Optical
Technique
Turbulence is a phenomenon that is present in many aspects of everyday life; even the act of
walking through a room generates complicated turbulent eddies in the wake of the walker. Atmospheric
particulates suspended in air are moved about by the complicated fluid motions associated with
turbulence, though the general behavior of particulates is unknown. The purpose of this project is to
explore the influence turbulence has on particulates is unknown. The purpose of this project is to explore
the influence turbulence has on particulate clustering via use of the Schlieren Photographic technique. This
light scattering technique can be used to investigate particle concentration fluctuations, which, in our
experiment, would be driven by turbulence. The light that hits the airborne particles is scattered, and the
scattering effect gives rise to an image that allows inference of the particle locations. Ultimately, statistical
properties of the spatial clustering of individual particles will be linked to properties associated with the
turbulence to attempt to quantify the effects of turbulence on particle clustering.
12.
Student: Tyler Perini
Major: Mathematics
Title: Wreck This Calculus Workbook Series
This continuing project aims to complete a series of calculus workbooks/journals for publication,
aimed towards secondary and post-secondary students. We will be attempting to overcome challenges faced
by educators in our field: Why are so many students turned off by math? How can we make it appealing and
relatable? What are some successful strategies in engaging students with calculus? These books approach
calculus from a new angle, providing a balanced development of concept- and calculation-based
understanding. Inspired by Keri Smith’s Wreck This Journal series, we invoke creativity as the primary vehicle
for instruction by appealing to kinesthetic learners and those who consider themselves as “non-mathminded.” Through student involvement and innovative designs, including physical activities, games, and
graphic novellas, we intend to engage the students who are most commonly disconnected from this
surprisingly lively and relatable subject. Highly illustrative, with a focus on visual cues and tactile
involvement, these books can appeal to all students, regardless of prior mathematical interest. In order to
accomplish this, we first intend to research design and educational strategies, existing and comparable texts,
and other sources for creative inspiration. We will then test the books in at least two classes of business
calculus and use the students’ feedback to improve upon their design. Finally, we will promote the series
through academic connections made through conferences and other disseminations of our work. As two
aspiring educators, we will get a hands-on experience of publishing an educational text by the completion of
this project.
13.
Student: Mariel Thottam
Major: Psychology
Title: Stress, Coping, and Autobiographical Memory
Everyone reacts to stress and trauma a bit differently. Some people are "cool under fire" no
matter how difficult life becomes; for others, a seemingly moderate trauma can lead to substantial
emotional distress, including post-traumatic stress disorder (PTSD). Research on PTSD has historically
focused on pharmacological or psychological therapies for people who have been traumatized;
however, recent studies have tried to identify risk factors that make one individual more susceptible to
trauma than another. Neurological research, for instance, has identified differences in a brain region
called the hippocampus, which is important for learning and memory: People with smaller
hippocampi are more likely to fall victim to PTSD. Although these results are interesting and
important, brain scans are cumbersome, expensive, and somewhat removed from the psychological
symptoms that trauma can bring about. What if you could predict someone's vulnerability to stress
and trauma with a simple paper-and-pencil test instead?
In our study, we will focus on tests of autobiographical memory (memories for events of
everyday life). Previous research has shown that overgeneral autobiographical memories – memories
that are vague and short on details – often go hand-in-hand with emotional distress or psychiatric
illness. We propose that this relationship exists because people with overgeneral memories are more
vulnerable to stress. More specifically, people might develop a tendency to remember in an
overgeneral fashion as a way of avoiding further exposure to stressful memories. If this is true, then we
can use these tests to predict who will have a poor reaction to subsequent major stressors.
14.
Student: Kelsey Marie Vollmer
Major: Biology
Mentor: Sorinel Oprisan
Title: Investigation of stimulus shape contribution to phase resetting curve
Neurons are excitable cells that are silent most of the time and only briefly produce a burst of
electrical activity called action potentials (APs) in response to inputs received from other neurons. Some
neurons are intrinsic burster capable of producing a periodic sustained electrical activity. Such spiking
neurons are frequently encountered as part of autonomous neural networks responsible for rhythmic
activities, such as flying, swimming, walking, chewing, etc., called central pattern generators (CPG). The
main mechanism used by neurons to respond and adapt to environmental stimuli is through changing their
firing frequency proportional to inputs received. The relationship between the external stimulus timing
and the change in the firing rate of the neuron is called a phase resetting curve (PRC). In addition to its
application to investigating the mechanisms that allow the same neural network to generate multiple
patterns of activities, e.g., the gait network can produce walk, trot, gallop, etc., the PRC can predict the
synchronous firing of a large network that occurs during epileptic seizures. Our work this summer will
focus on investigating numerically the relationship between the shape of the external perturbation and the
PRC. For this purpose, a model neuron will be used to map the effect of external perturbations, such as
the amplitude, duration, rate of change of inputs from other neurons, and the PRC.
15.
Student: Benjamin Wilson
Mentor: Joe Carson
Title: Extrasolar Planets and Disk Imaging using the Hubble Space Telescope
The Hubble DICE survey is an observational program approved by NASA. The team consists of
nineteen multinational experts in the field of astrophysics. Led by Dr. Glenn Schneider (Univ Arizona),
there is an ongoing effort to study eleven carefully chosen stars with known circumstellar disks. The
disks surrounding these young stars are interesting because they are believed to be the birthplaces of
planets. By discovering evidence of planet formation in these disks, either by imaging disk gaps caused by
forming planets or by directly imaging the planets themselves, one can gain invaluable insights to guide
planet formation theories and ultimately help better understand the origins of our own solar system.
We use the STIS camera equipped on the Hubble Space Telescope to observe our target stars,
utilizing high resolution imaging techniques to probe precise and detailed structures of the circumstellar
disk. Aided by the precision of the STIS camera, combined with the sensitivity of the Hubble Telescope,
we collect data from these target stars at multiple telescope roll rotations. These observations allow us
to, for the first time, explore substructures and, in particular, asymmetries that indicate the presence
of recently formed planets.
In particular, I have been working under the guidance of Dr. Joe Carson to develop a VariablePixel Linear Reconstruction, or “Drizzling”, procedure. This allows us to take advantage of the multiple roll
angles in order to sub-pixelate the final image and increase the effective imaging resolution. We have
successfully proven that this procedure, among others, aids the clarity of the disk and will be applied to our
additional targets.
Research Presentation Grants (RPG)
1.
Student: Olivia Adams
Major: Anthropology
Mentors: Maureen Hays
Departments: Anthropology
Kimberly Pyszka
Title: Landscape Archaeology and GIS: Understanding Cultural Adaptations and Tenant
Farming in the Low Country, Hollywood, SC
Conference: South Eastern Archaeological Conference
Dixie Plantation (Hollywood, SC) has a long history of occupation, though little is known about
the period post-Civil War, a time of social and economic change. For this research, the focus is on the
transition of tenant farming through the mid-20th century. The ephemeral nature of tenant sites and the
social significance of the transition mark this as a critical period for investigation. A preliminary picture of
tenant farming will be presented through the analysis of existing architecture, historic documentation, and
material culture. Using GIS to geospatially reference structure, site, and resource location allows for
exploration on how alterations in landscape usage communicate changes in social relationships.
2.
Student: Omorose Aighewi
Major: Biochemistry
Mentors: Wendy Cory
Departments: Chemistry and Biochemistry
Title: The Photodegradation of Ranitidine in the Aquatic Environment
Conference: 2015 International Pittsburgh Conference on Analytical Chemistry and
Applied Spectroscopy
Because of the wide use of pharmaceuticals, there is now increasing concern about their possible
presence in public water systems and the surrounding aquatic environment. When exposed to UV light,
the active compounds in some medications have been observed degrade into compounds that may pose
a threat to aquatic life. In this research, the photodegradation of ranitidine (the active drug in Zantac®,
an acid reflux medication) was investigated under simulated environmental conditions. The rate of solar
photodegradation was determined for ranitidine in aqueous solution and in solutions containing humic
acid, an important form of dissolved natural organic matter found in the aquatic environment, following
photoexposure of these solutions in a solar simulator. Future work before the conference will include
identifying the products of photodegradation using a chemical analysis technique called liquid
chromatography-mass spectrometry (LC-MS).
3.
Student: Zak Bartholomew
Major: Anthropology
Mentor: James Newhard
Norman Levine
Title: The Development of a Legacy GIS for the Contextualization of the Linear B Deposits from the
Palace of Nestor at Pylos
Conference: Archaeological Institute of America Annual Meeting
The Palace of Nestor has been an important site for scholars since it was first excavated. One
of the noteworthy classes of artifacts is the administrative evidence in the form of Linear B tablets and
sealings. Concurrent with the formal, traditional publication of this assemblage is the development of
a visual and spatial informatics system. One of the sub-tasks includes the creation of a GIS to spatially
locate the fragments within the palace. While the location of the objects have been emphasized in
previous studies, geospatial applications have advanced such that the spatial location of the tablets can
be linked to other information and presented in a format that facilitates querying and exploration by
the user. This project will give users the ability to query by tablet and series data. Results are
displayed within a site map that shows the location of each queried fragment.
4.
Student: Elizabeth H. Blankenship Major: Biochemistry
Mentor: Jennifer L. Fox
Wendy Cory
Title: Metabolite Profiling of Saccharomyces cerevisiae by Liquid Chromatography-Mass Spectrometry
Conference: Southeastern Regional Meeting of the American Chemical Society
Metabolomics is a field capable of improving medical diagnoses, drug therapies, and our current
understanding of cell biology. Metabolites are small molecules that act as signatures of biochemical
activity at the cellular level, detected primarily through liquid chromatography-mass spectrometry (LCMS), a technique that allows for identification of the chemical compounds in a sample. To investigate
metabolic differences experienced by cells in response to varying cellular conditions, we developed
methodology for metabolite extraction of baker's yeast and analysis by LC-MS. Our results will be
presented at this conference, including the reproducibility of this method for analysis of independent
biological samples.
5.
Student: F. Garrett Boudinot
Major: Geology
Mentor: Vijay M. Vulava
Department: Geology
Title: Sorption and Transport of Sildenafil in Natural Soils
Conference: Annual Meeting of the Geological Society of America
Pharmaceutical Chemicals mainly enter our ecosystems from discharges of treated wastewater, and
have direct effects on their ecological health. Sildenafil (Viagra) is one such chemical, whose effect
on natural ecosystems is heretofore unknown. Given that sildenafil consumption (and concurrently
disposal) is on the rise, it is essential that its behavior in the natural environment be understood. Thus,
the goal of this study was to quantify how sildenafil travels and functions in differing natural soils.
Experiments were performed using pristine organic-rich and clay-rich soils collected in a managed forest
near Charleston, SC. Data from the experiments indicate strong chemical bonding of sildenafil to all soils,
with clay-rich soils showing even higher bonding. Soil bonding acts as a filter in groundwater, effectively
removing those bound chemicals from the water system. These results show that very little sildenafil will
remain in the groundwater upon discharge into natural soils.
6.
Student: Haley Cabaniss
Major: Geology
Department: Geology
Title: Prediction of Catastropic Eruptions of Colima Volcano, Mexico, via Analyses of Long-term
Trends in Lava Chemistry
Conference: Geological Society of America’s Annual Conference
As the most active volcano in Mexico, Volcan de Colima is an excellent laboratory for
understanding patterns of eruption activity and how the chemistry of its lavas and gases varies over
time. Understanding how the chemical signatures of these volcanic products evolve may allow for
improved predictions of the particularly powerful and deadly eruptions that occur at Colima about
once every century. Working with a professional colleague in Mexico, student Haley Cabaniss collected
lava samples in Colima during the summer of 2014 from several eruptions dating back to the 1960s.
In this study, Haley and her College of Charleston mentor Dr. John Chadwick are analyzing the
chemistry of Colima lavas and volatile gases trapped in tiny inclusions within these samples to
understand how their variability relates to the pattern of eruptions over time to identify patterns in
volatile behavior that signal the start of eruptions.
7.
Student: Christine Logan Chambers Major: Psychology
Mentor: Lisa Thomson Ross
Title: The Role of Sex Education for Reducing Risky Behaviors
Conference: Society of Southeastern Social Psychologists
Early sexual behaviors (ESBs) and risky sexual behaviors (RSBs) put young adults in danger of
unwanted outcomes (STD/STI, pregnancy, sexual aggression). The current study focused on the prevention
of ESBs/RSBs through sex education. Secondary data was used to test the hypothesis that students
reporting higher quality sex education would have lower reports of ESBs/RSBs. College women (N=260,
73% Caucasian, M = 19 years) completed a survey on the quality of sex education (family and school) and
ESBs/RSBs. Sex education quality was more valuable from mothers than fathers. Participants who reported
the sex education from their mothers as more valuable were more likely to report their first sex was with a
partner they had known longer and closer to their age. Participants reporting more valuable father sex
education also reported fewer sexual hookups. Surprisingly, school sex education was unrelated to
ESBs/RSBs. Family-based sex education can be valuable for reducing ESBs/RSBs.
8.
Student: F. James Claire
Major: Chemistry
Mentor: Richard Himes
Title: Synthesis of novel dual-active antimitotic chemotherapies
Conference: South Eastern Meeting of the American Chemical Society
The goal of this project was to design and synthesize a novel chemotherapeutic compound. One
way to make chemotherapies more effective is to design the drugs such that they will bind to multiple sites
within cells to disrupt several cell processes. Our compound was designed based on the chemically- active
structures of two molecules that are known to inhibit cell division in different ways. Combretastatin
A-4 (CA4), the first of these molecules, attacks microtubulin within a cell to prevent cell division. The
second molecule is a Roche drug that suppresses tumors by attacking a specific site abundantly found in
tumor cells of many types of cancer. The combination of these two compounds’ structures will allow
our novel chemotherapy to bind to both of these sites therefore having greater cytotoxicity to cancer cells.
9.
Student: Lundy Davis
Major: Biology
Mentor: Brooke Van Horn
Title: Iodinated Hydroxylamines for X-ray Opaque Polyester Materials
X-ray imaging is a common technique used in medical science in which contrast agents injected
in the body are illuminated to detect and diagnose disease states. Our lab aims to guide X-ray imaging
science away from the current limitations associated with small molecule contrast agents and toward
polymer systems. The polymeric systems we are building have the benefit of being tunable in size and the
potential to target tissues, diagnose/image and treat disease through personalized medicine. In summer
2014, we fulfilled our goal of successfully synthesizing a triiodo small molecule and conjugating it to
varying polymer chains. We will continue to improve the synthesis and purification of the triiodo small
molecule and conjugate it to polymer chains for higher iodine concentration, as well as evaluate our
products using Nuclear Magnetic Resonance (NMR) and Gel Permeation Chromatography (GPC) at
CofC and by X-ray analysis with collaborators at Clemson University.
10.
Student: Lauren Deasy
Major: Psychology
Title: Sociability, Personality, and Autobiographical Memory
Conference: Annual Meeting of the Southeastern Psychological Association
Our memories provide us with a record of where we have gone, what we have done, and who we
have been. On a social level, they connect us to a point in history (as with memories of 9/11), and they
help us establish relationships with others. Most people recall memories that are detailed, rich, and vivid;
however, other people report memories that are overly general, and they cannot provide specific details,
even when pressed. People who tend to retrieve overgeneral memories are vulnerable to depression and
other mental illnesses as well as several forms of cognitive decline.
In this study, we examined the relationship between personality, social support, and memory in
older adults. We found that strong support of family members led to stronger and more positive
autobiographical memories; the support of friends had no significant effect. We now plan to present
these findings at the Southeastern Psychological Association's annual meeting.
11.
Student: Taylor Domenick
Major: Biochemistry
Mentor: Wendy Cory
Title: Photodegradation of Fluoxetine in the Aquatic Environment
The effect of the release of pharmaceuticals into the environment is gaining attention due to their
potentially deleterious effects on aquatic organisms. Selective serotonin reuptake inhibitor fluoxetine
(Prozac®) has been reported to persist (remain) in the aquatic environment. Photoexposure has been
documented to degrade pharmaceuticals and result in the formation of new compounds (products) with
diverse activities. In this work, aqueous solutions of fluoxetine were exposed to simulated sunlight with
and without humic acid (HA), a form of natural dissolved organic matter found in the environment,
to mimic natural water conditions. After light exposure, the samples were chemically analyzed and the
rate of fluoxetine photodegradation was determined. Data indicated that the half-life of fluoxetine in water
was 46 hours, meaning it took almost two full days for half of the sample to degrade. Humic acid was
observed to speed up the degradation reaction.
12.
Student: Tess Dooley
Mentor: Robert Podolsky
Department: Biology
Title: Fertilization in single- and multiple-male spawnings under elevated CO2: implications for
reproductive success in response to ocean acidification
Conference: Society for Integrative and Comparative Biology Annual Meeting
Ocean acidification (OA), where CO2 is absorbed by the ocean, is of major ecological concern
because it interferes with pH-sensitive biological processes. Our recent research suggested that predicted
near-future levels of OA will negatively impact fertilization in the sea urchin, Arbacia punctulata.
However, recent literature reviews have noted that OA more weakly affects fertilization in studies that
mixed gametes from multiple mating pairs. To test the hypothesis that group spawning reduces the negative
effects of OA, we measured fertilization success under current and 2.5x-current CO2 conditions using
single- and multiple-male crosses. We did not find a significant effect of CO2 on fertilization and the
multiple-male crosses did not show greater resistance to the effects of CO2. However, the multiple-male
crosses showed significantly lower fertilization than the average fertilization of the single-male crosses,
indicating an interaction among sperm that could reduce fertilization success for females that spawn in
larger aggregations.
13.
Student: Aliya Dumas
Major: Biochemistry
Mentor: Wendy Cory
Department: Chemistry & Biochemistry
Title: Photodegradation of Diphenhydramine
Pharmaceuticals enter the sewage system as the result of human excretions or improper disposal of
unused medications. Often, these compounds are not wholly removed during the wastewater treatment
process. Once in the aquatic environment, they are then exposed to sunlight which facilitates
photochemical degradation. In this work, the photodegradation of diphenhydramine (Benadryl®, a
common antihistamine) in aqueous solution was investigated. Solutions were exposed to light in a solar
simulator, then chemically analyzed in order to measure the amount of diphenhydramine left in solution as
well as any new compounds (products) that might have formed as a result of the photochemical
reactions. The effect of humic acid, a form natural organic matter found dissolved in natural water
samples, was investigated. The resulting data was used to determine the rate of the photodegradation
reactions, and the products of these reactions were also measured and identified.
14.
Student: Hannah Evans
Major: English
Mentor: Simon Lewis
Department: English/International Studies
Title: Chimamanda Ngozi Adichie against the single story: intersections of virtual space,
transnationalism, and feminism
Conference: British Commonwealth and Postcolonial Studies Conference
This project explores Nigerian author Chimamanda Ngozi Adichie’s layered narrative in her novel
Americanah. Adichie writes virtual space in a transnational context, through her protagonist’s blogs, to
scrutinize racism in the U.S. and give intersectional perspectives on feminism and nationality. She inhabits
multiple spaces, both literary and actual, rejecting a “single story” of Nigerian literature. A close
reading of Adichie’s fiction and that of relevant African and African-American contemporaries forms my
foundation. I situate this reading within the context of Adichie’s presence in popular culture, including
TED talks, online articles, and a blog based on her protagonist’s blog in Americanah. I examine how
Adichie inserts herself into and pushes against Nigerian literary tradition. Virtual space in Americanah gives
insight into how Adichie’s transnational status enables her bold comments on American racism and crosscultural feminism. Virtual space connects the narrative functions in Americanah to Adichie’s participation in
popular and literary discourse.
15.
Student: Chloe Fletcher
Major: Data Science
Mentor: Jason Howell
Title: Dynamic Modeling of Targeted and Non-targeted Advertising Strategies
Conference: Institute for Operations Research and the Management Sciences 2014
Annual Meeting
With the growing collection of data regarding the depth of detailed knowledge of consumer
habits and trends, firms are gaining the capability to discern customers of other firms from the market of
uncommitted consumers. Firms with this capability will be able to implement advertising campaigns
where the advertising effort towards customers of competing firms differs from that towards uncommitted
customers. We develop two mathematical models for the dynamic behavior of sales due to competitive
advertising in a setting with a small number of competing firms. One model (non-targeted) assumes the
advertising effort is the same for both categories of customers, and the other model (targeted) gives firms
the capability to allocate advertising effort across the two categories differently. The models are
mathematically analyzed and we formulate and answer several strategic questions that a firm may face
when implementing a targeted policy.
16.
Student: Malka Fox-Epstein
Major: Public Health
Mentor: Beth Sundstrom
Department: Communication/Public Health
Andrea DeMaria
Health and Human Performance
Title: Investigating correlates of daily and nondaily contraception use among college-aged women
Conference: 142nd American Public Health Association Annual Meeting and Exposition
One third of unintended pregnancies in S.C. are among women in their twenties. The majority of
these women use “the pill” as their primary method of birth control, which has a higher failure rate than
nondaily contraception. This study investigated correlates of daily and nondaily contraception use. 663
participants aged 18-24 years completed self-administered web based surveys. Contraception methods were
categorized as daily (oral contraceptive pill) and nondaily (IUD, implant, injection, patch, vaginal ring).
Results showed nondaily users were more likely to have a history of vaginal (p=.02) and anal (p=.01)
intercourse, giving (p=.02) and receiving (p=.02) oral sex, and greater frequency of solo masturbation (p<.01)
during the past four weeks than daily users. Those classified as overweight or obese were significantly more
likely to primarily use nondaily contraceptive methods (OR 3.82; 95% CI [1.61, 8.77]; p<0.01). Findings
suggest opportunities to increase uptake of nondaily methods among college-aged women.
17.
Student: Megan Freifelder
Major: Elementary Education and Dance
Mentor: Gretchen McLaine
Department: Theatre and Dance
Title: To “e” or not to “e”? Using technology for enhanced collaborative learning and self-reflection
Conference: National Dance Education Organization Conference 2014
Our research project, “To e or not to e,” is a study on how technology, specifically the use of eportfolios, can expand the way artists engage in collaborations, receive and apply feedback, and how they
can be effectively used to assess dance education practices and outcomes. E-portfolios are a key tool to
artists’ engagement in meaningful assessments and reflective practice. Our research demonstrates the need
for dance educators to incorporate e-portfolios and other technology into their teaching, and that
prospective employers in this market prefer seeing the applicant’s work in one place and in a creative, up-todate, format. The resulting presentation will provide attendees easy-to-use, practical applications for
implementing various technologies in their classrooms, and the value of such.
18.
Student: Madeleine Gordon
Major: Chemistry
Title: Mixed-solvent Directed Assembly of Poly(3-hexylthiophene) Films
Organic photovoltaic (OPV) materials are a growing field in the area of solar cell research.
Poly(3-hexylthiophene) (P3HT) is a common photovoltaic polymer used in the construction of OPVs
and the structure of solid P3HT thin films plays a central role in device efficiency. Our research explores
the structural order and assembly of P3HT thin films through fine adjustments made in the composition
of solvent mixtures used to process these solar cell materials. We have used different optical and atomic
force microscopy imaging techniques to observe the structure of the film surfaces, which is critical to the
efficiency of P3HT-based solar cells. Our research has shown that small changes in the composition of
binary organic solvent mixtures and P3HT film processing procedure lead to drastic changes in the P3HT
film structure. Our observations will help improve our understanding of what structures are optimal for
the performance of P3HT-based solar cells.
19.
Student: Avigeet Gupta
Major: Biochemistry
Mentor: Timothy Barker
Department: Chemistry
Title: Synthesis of Unnatural Amino Acids
Amino acids are the basic building block of all living things. There are twenty naturally
occurring amino acids in nature. We examined methods to make unnatural amino acids in the
chemistry laboratory that have previously never been made. These unnatural amino acids will then be
connected into a string of natural amino acids. We focused our efforts on the synthesis of the unnatural
amino acids.
20.
Student: Nicholas J. Harris
Major: Biology
Title: Mutational Analysis of Heme A Synthase
Proteins act as the agents that orchestrate an intricate series of chemical reactions in our bodies'
cells, through which all of the components of the cell are created, broken down, and transformed into
useful molecules. There are thousands of unique proteins within a cell, each with its own specific role.
The goal of this project is to understand how the cell synthesizes the large protein complex
cytochrome oxidase, which has a crucial r o l e in the cell’s ability to generate energy. Improper function
of cytochrome oxidase can lead to a broad range of negative impacts on human health. To determine
the mechanism for the complicated assembly process of cytochrome oxidase, we focused on one of the
steps that is not yet understood (specifically, cofactor synthesis and installation into the maturing
complex). We investigated this step by altering the enzyme responsible for performing it and analyzing
the effects of those modifications.
21.
Student: Alyssa Johnson
Major: Geology
Department: Geology
Title: Analyzing the Eruptive Phases of the Blue Dragon Lava Flow through Hyperspectral and
Multispectral Remote Sensing and Geochemical Analysis
Conference: Geological Society of America 2014
The Blue Dragon flow resulted from a volcanic eruption approximately 2,000 years ago at
Craters of the Moon National Monument in Idaho, and is one of the largest single lava flows in the
contiguous United States. Field work conducted by Dr. John Chadwick and student Alyssa Johnson in the
summer of 2014 revealed that the flow resulted from multiple eruption phases. Geochemical analysis on
the collected lava samples is performed using X-Ray Fluorescence (XRF) for major and trace elements at
external laboratories after preparation in Dr. John Chadwick’s high temperature geochemisty lab.
Chemical analysis of the lava samples reveals that the magma supplying these eruptions evolved over time
in a shallow magma chamber. Remote sensing satellite images are also being used to determine the
boundaries and volume of the eruptive phases.
22.
Student: Savannah Jones
Major: Biochemistry
Department: Chemistry
Title: Lewis Acid-Catalyzed Minisci Reactions
Heterocycles are molecules with a ring of carbon atoms that also contain nitrogen, oxygen or
sulfur. Heterocycles are an important class of molecules to study because they are often found in drug
candidates and medicines. The ability to easily modify a heterocycle is useful to medicinal chemists because
they are then able to create many drug candidates with slightly different structures and physical
properties. We developed a method to modify heterocycles to provide medicinal chemists an efficient way
of preparing many different drug candidates from a single heterocycle starting material.
23.
Student: Lisa Kasprzok
Major: Chemistry
Mentor: Wendy Cory
Title: Solar Photodegradation of Sertraline in the Aquatic Environment
Pharmaceuticals are being released into our aquatic environment by wastewater treatment plants
and are increasingly being detected along with the products that they turn into after chemical reactions
in the environment. These new compounds can be more toxic than the pharmaceutical itself. We
investigated what happens when solutions of sertraline (Zoloft®), a commonly prescribed anti-depressant,
are exposed to sunlight. Some solutions contained humic acid, a form of natural organic matter that is
found in the aquatic environment. Samples were photoexposed in a solar simulator and analyzed at
certain time points. As expected, the concentration of sertraline was observed to decrease due to
photodegradation. Sertraline was observed to photodegrade quickly, within the course of a day; added
humic acid made it photodegrade even faster. Future work, to be included in the presentation, will include
evidence of new compounds that formed using a chemical analysis technique called liquid chromatographymass spectrometry (LC-MS).
24.
Student: Kellen Lawson
Major: Astrophysics
Mentor: Joe Carson
Title: Searching for Extrasolar Planets with the Subaru SEEDS Survey
Conference: American Astronomical Society 225th Meeting
This research comprises the major part of the High-Mass Star study within SEEDS, a direct
imaging exoplanet survey. Observations for the survey are carried out using the 8-meter Subaru Telescope’s
HICIAO camera in near-infrared wavelengths. We utilize sophisticated software to remove much of the
star's light in the images in order to resolve the relatively much fainter planetary light. Once confirmed,
additional observations may allow for a wealth of information to be uncovered regarding the planet –
including planet temperature, composition, and atmospheric chemistry. These measurements aid in filling
a significant gap in the census of exoplanet data, and will help to reach a more complete understanding of
the nature of these astronomical bodies. In January, the survey's progress to date will be reported –
including the nature of the novel methods used in processing our data, improved software sensitivities, and
the prior discovery of the Super-Jupiter planet Kappa Andromedae.
25.
Student: Robert Lemasters
Major: Physics
Mentor: Mike Larsen
Title: Investigating the Dependence of Fractal Dimension on Raindrop Size for Drop Arrival
Times as Measured by a Two-Dimensional Video Disdrometer
Conference: American Geophysical Fall Meeting
The statistical structure of rainfall is an important, yet not well characterized subject in the field
of atmospheric microphysics. For most purposes, raindrops are assumed to arrive in a completely
random fashion. However, when rainfall is looked at closer, one will find that this is not quite the case and
that rain has an inherent “clumpyness” to it. This project is mainly focused on characterizing this observed
deviation from perfect randomness and how this evolves throughout a given storm. There exist a variety of
methods that can used to better identify these deviations, but for this project we attempt to calculate
what’s called the “Monofractal Dimension” of a storm because of its easy implementation and relatedness
back to physical phenomena. With data provided by a novel rain-measuring instrument array located at
Dixie Plantation in Hollywood, SC, we have developed a better understanding of the behavior of rain.
26.
Student: Danielle Massé
Major: Applied Mathematics
Mentors: Jason Howell
Title: Newtonian and Non-Newtonian Fluid Dynamics in Abdominal Aortic Aneurysms
Conference: Society of Industrial and Applied Mathematics Conference on
Computational Science and Engineering
Prevalence of abdominal aortic aneurysms in the general population is estimated to be at least
2%, and rupture of these aneurysms often directly leads to mortality. Biomedical research has indicated
that dynamic characteristics of the blood flow inside arteries with aneurysms are risk factors for both the
enlargement and rupture of the associated aneurysm. In Summer 2014 this project analyzed these blood
flow characteristics inside arteries with aneurysms from a mathematical and computational standpoint. In
the model, an idealized shape of an aneurysm was constructed and subsequently adjusted to account for
characteristics found in actual aneurysms. Data from the simulations indicated that the force along the
arterial walls of an asymmetric aneurysm presents a larger gradient than symmetric aneurysms, which
could lead to further growth and possibly rupture of the modeled aneurysm. Ongoing research will extend
these simulations to more realistic geometries and fluid parameters.
27.
Student: Grace Moxley
Major: Biology
Mentors: Andrea DeMaria
Department: Health and Human Performance
Beth Sundstrom
Public Health/Communication
Title: Predicting women’s responses to contraceptive campaign messages: An application of the theory
of planned behavior
Conference: Society for Public Health Education 66th Annual Meeting
Despite widespread use of the oral contraceptive pill (OCP), half of all pregnancies in the US
remain unplanned. Nondaily (e.g., vaginal ring, patch) contraceptive options offer an alternative approach
that has proven more effective than the OCP in preventing pregnancy. Despite high rates of unintended
pregnancy, reported lack of satisfaction with traditional methods, and the success of nondaily options in
studies and clinical trials, women in the US continue to rely on the OCP as their primary birth control
method.
Long-acting reversible contraceptives (LARC) (e.g., intrauterine device, implant, injection), a
category of nondaily contraception, eliminate the possibility of user error and offer higher rates of
effectiveness. The recent Affordable Care Act requires that all FDA-approved contraceptives, including
LARC methods, must be covered by health insurance. Research suggests with the barrier of price removed,
LARC methods become a more realistic option for all women.
This research project offered an interdisciplinary approach to investigate psychological, clinical, and
behavioral factors impacting contraceptive choice. Research findings will extend public health and
communication concepts, methods, and theory to offer practical recommendations for campaign
development.
28.
Student: Marino Mugayar-Baldocchi
Major: Psychology
Mentors: Anthony Bishara
Title: Anchoring Effects on Earliest Autobiographical Memories
Conference: Annual Meetings of the Psychonomic Society and Society for Judgment and
Decision Making
The current project investigated the malleability of people’s earliest memories. We were
particularly interested in whether participants’ reported age of their earliest memory could be
influenced by a subtle cognitive technique called anchoring. Anchoring is the choice of an arbitrary
number that influences a person’s estimate. There were two conditions with an anchor present, one to pull
the age estimate up and one to bring it down, and a control condition with no anchor. After reporting
the age of their earliest memory, participants then had to rate certain aspects of that memory on 7
point scales. The results suggested that participants’ estimates were pulled up by the anchor but were not
brought down the other anchor. Moreover, the reported age of the memory was more malleable if the
person recalled the event in a third person perspective as opposed to a first person perspective.
29.
Student: Joye Nettles
Mentor: James Bowring
Department: Computer Science
Title: CHRONI – An Android Application for geochronologists to access archived sample analyses
from the NSF-funded GeoChron.org data repository
Conference: 2014 American Geophysical Union Fall Meeting
Today, geochronologists are archiving their data and results to public cloud archives managed by the
NSF-funded GeoChron database. The software application U-Pb_Redux[l,2,3] developed by Dr.
Bowring at the College of Charleston provides seamless connectivity to GeoChron for geochronologists
to automatically upload and retrieve their data. CHRONI i s a mobile application for Android devices
that provides easy access to this information. With CHRONI, geochronologists can view archived data
and analyses downloaded from the GeoChron database, or any other location, in a customizable format.
CHRONI use s special documents called Report Settings to create the customized data display on a
mobile device. In addition to providing geologists effortless mobile access to archived data and analyses,
CHRONI allows users to manage their GeoChron credentials, quickly download private and public
files, and view specialized graphics associated with particular files. Future versions of CHRONI will be
developed to support iDS-compatible (iPhone, iPod, and iPad) devices.
30.
Student: Samantha E. Nicolau
Major: Biochemistry and Biology
Mentor: Brooke Van Horn
Department: Chemistry & Biochemistry
Title: Investigations into the Ring-Opening Polymerization of 1,4,8-trioxa[4.6]spiro-9-undecanone
(TOSUO) using an Organocatalyst
Current polymer science is evolving in its preparation of materials for an expanding variety of
applications and to fill those needs, synthetic chemists must have precise control over the properties of
those materials and therefore the means that we employ to make them. We are exploring organic
catalysts for the synthesis of materials using analog molecules of epsilon-caprolactone. These polymers have
significant value in biomedical applications where the health and safety of the material may require
moving away from traditional heavy metal catalysts. We are preparing copolymers of epsiloncaprolactone and a ketal-containing analog as a means to introduce functional groups in the polymer in
subsequent chemical reactions. Interestingly, we create polymers with one monomer inserting preferentially
rather than randomly or statistically early in the polymerization process, giving gradient copolymers. This
undergraduate presentation will highlight our preliminary results using NMR and GPC characterization
of the polymerization process and final products.
31.
Student: Brenna C. Norton-Baker Major: Biochemistry
Mentor: Marcello Forconi
19
Title: Introduction of FT-IR and F NMR probes in proteins via SNAr
Many proteins need to fold in a globular structure t o perform their functions. A folded
protein can harbor microenvironments with significantly different characteristics. The development of
specific probes to determine the properties of these microenvironments is an active area of research.
We have used a simple chemical reaction to modify proteins and site-specifically in troduce probes
suitable for vibrational spectroscopy and nuclear magnetic resonance. This reaction uses cheap and
relatively safe reagents, making it suitable for settings such as undergraduate institutions.
32.
Student: Derek Novo
Major: Physics
Mentor: Sorinel A. Oprisan
Title: Fluctuations in network’s parameters and their effects on the shape of interval timing output
Conference: Annual Meeting of the Society for Neuroscience
In most species, decision making, rate calculation, and planning necessitate temporal estimations
in the seconds-to-minutes range (interval timing). Briefly, a conditioning stimulus (light or sound) is
presented to a subject for a to- be-learned duration and the subject's first response after the stimulus is
terminated is reinforced with a reward. After this training, the conditioning stimulus is instead
presented for threefold the duration of the learned time without reinforcement. During this procedure,
the subjects respond less at the beginning, most around the learned time, and then gradually less as the
trial ends, following a tailed Gauss-like distribution with a standard deviation proportional to the learned
time. We used a computational network of oscillators that mimics the activity of some neurobiological
structures known to be involved in interval timing. We found that small fluctuations of the network’s
parameters have specific signatures that help to reveal the source of noise perturbing the network.
33.
Student: Tyler Perini
Major: Mathematics (Applied)
Title: The Humility Project: Text Analysis for Characteristic Linguistic Patterns
Conference: Southeastern Chapter of the Institute for Operations Research and the
Management Sciences
There has been a growing interest in using language data to identify, quantify, and differentiate
individuals as either having or lacking certain traits, and in this research, our interest lies in humility. We
hope to empower the developing concept of humility’s psychological construct by unveiling the hidden
linguistic trends in self-reported answers from volunteers, treating sentences from responses as documents,
while comparing to the individuals’ respective humility scores. After initial data collection, we use a web tool
to extract usage of terms, parts of speech, and semantic categories, which will initialize a sparse feature-bydocument matrix, A, where we then introduce some term-weighting methods. By applying nonnegative
matrix factorization (NMF), we decompose this matrix into two matrices that identifies some k number of
trend vectors that best describe the data set: the W matrix specifies the weights of the terms’ belonging to
each topic, and the H matrix shows the topic distribution over the documents. By varying the values for k,
and manipulating the weighting schemes used, we hope to find valuable topics that are uniquely
characteristic for the ’humble’ documents. From the topic-by-document H matrix, we may cluster the
documents and evaluate the significance of the specified topic vectors; on the other hand, the term-by-topic
W matrix allows us an easy resource for visualization, i.e. by creating word clouds of the characteristic words
within the descriptive topics. With further improvements, the objective for this research is to create a tool
that can predict the humility of an unknown query document.
34.
Student: Dillon Presto
Major: Chemistry
Brooke Van Horn
Title: Progress Toward P3HT Block Copolymers from Modular “Click” Syntheses
Organic photovoltaic materials show significant promise in creating more efficient solar cells.
Unlike traditional silicon-based solar cells, organic-based materials are relatively lightweight, inexpensive,
and their optical properties can be manipulated and optimized. Poly(3-hexylthiophene) (P3HT) is a
benchmark polymer in organic photovoltaic devices. However, in many organic solvents P3HT, the electron
donor, separates from the electron acceptor, such as quantum dots. Our research aims to solve this
problem by adding small amounts of copolymers, which dramatically increase organic photovoltaic device
performance, to P3HT blends. We seek to couple P3HT to polymers such as polystyrene that affinity for
electron acceptors using a novel "click" chemistry methodology. This approach will give us greater control
over the molecular architecture of the polymers. Once perfected, we will use this method to create a
library of copolymers with varying chain lengths, which will serve as the basis for future research on
polymer properties and device performance.
35.
Student: Caitlin Purvis
Major: Biology
Mentor: Wendy Cory
Title: The Photodegradation of Bupropion
Pharmaceuticals and over-the-counter medicines have been observed to have environmental effects
due to human consumption and subsequent excretion of medications as well as the improper disposal of
these products. Once introduced into an aquatic environment, drugs may further degrade into more
toxic moieties which may harm humans and aquatic organisms. We investigated the effects of exposing
solutions of bupropion (Wellbutrin®), an anti-depressant and smoking cessation aid, to simulated sunlight.
Some solutions contained dissolved organic material, humic acid, which is naturally found in the aquatic
environment. Samples were exposed to simulated sunlight for specific time periods so we could determine
the concentration of bupropion after exposure. After photoexposure, bupropion in solution quickly
degraded in less than a day, and the addition of humic acid aided in degradation. Future work will include
identifying the photodegradation products and their toxicity using a chemical analysis technique called
liquid chromatography-mass spectrometry (LC-MS).
36.
Student: Carson Reed
Major: Biochemistry
Title: Synthesis and Evaluation of a Novel, Bis-indenyl “Batwing” Ligand
Often, it is necessary for synthetic chemists to utilize chemical additives called catalysts to speed
up the rate of reactions and to increase reaction efficiency. Efficiency is key in various chemical industries,
such as in the pharmaceutical industries and materials development (e.g., polymers). The advent of efficient
chemical reactions in the pharmaceutical industry not only lowers the economic cost of synthesizing
new drugs, and it also can open up novel synthetic routes to new drugs or other necessary compounds. My
research involves the design and synthesis of a specific catalyst that can achieve this efficiency in the
synthesis of new compounds with practical applications. Currently, I have successfully synthesized my
catalyst precursor and will be investigating how this compound can be used to speed up the rates of certain
reactions.
37.
Student: Luke Rein
Major: Biology
Mentor: Allison Welch
Department: Biology
Title: Toxicity of combinations of naproxen and its photodegradants
Pharmaceutical compounds have been observed in natural waterways, due largely to their
incomplete removal from wastewater. In the environment, ultraviolet radiation can degrade these
pharmaceuticals into other biologically active compounds. However, continual input of common
pharmaceuticals results in pseudo-persistence, whereby enough new material is added that levels remain
elevated in spite of their breakdown. We investigated the effects of UV photodegradation and pseudopersistence on the toxicity of naproxen, a common anti-inflammatory. Southern toad tadpoles were
exposed to naproxen, its two degradants, and combinations of these three compounds in proportions that
correspond to laboratory observations of naproxen photodegradation. Naproxen’s two degradants were
significantly more toxic than naproxen itself, and combinations of naproxen and its photodegradants were
particularly toxic. These data suggest that the ecological effects of pharmaceutical pollutants may be
underestimated.
38.
Student: Enis Sanchez
Major: Chemistry
Title: Using Bio-Based Materials to Synthesize a Novel Surfactant in the Production of
Polyurethane Foams
The primary focus of this research is to improve foam formation in the production of polyurethane
foams, using bio-based materials. Industrially, poly-ethylene glycol based surfactants are derived from
petroleum oil. In contrast to these petroleum-based surfactants, our surfactants are based on renewable fatty
acid sources, thus being more environmentally favored. Surfactants reduce the surface tension between
isocyanates and poly-ether or poly-ester based polyols, which allows for more uniform mixing during
polyurethane formation. We have started synthesizing polyurethane foams, comparing foams made with
bio-based surfactants to foams made with traditional surfactants. Image analysis based on scanning electron
microscopy will allow for comparisons of average foam cell size distributions between the polyurethane foam
samples. Upon further interpretation of the results, we hope to conclude that polyurethane foams
synthesized using bio-based surfactants are comparable to polyurethane foams manufactured using
petroleum-based surfactants used in industry.
39.
Student: Justin Skinner
Major: Biology
Mentor: Robert Podolsky
Department: Biology
Title: Sensory Neuron Plasticity During Claw Transformation in the Snapping Shrimp, Alpheus
angulosus
Conference: Society for Neuroscience 2013 Annual Conference
Alpheus species’ claws are bilaterally asymmetrical: they possess a pincer and a snapper claw that
differ both functionally and morphologically. Both claws play important roles in the behavioral
interactions of the shrimp. When the snapper is removed, the pincer will morph over a period of four
molts into a functioning snapper claw, which has the unique ability of producing a “snapping” sound
when the shrimp rapidly closes the large claw. Transformation occurs through a step-like change in
shape, nerve growth, and muscle tissue. Setae, hair-like structures on the claw, are the outward projections
of sensory nerves; they provide a unique opportunity to use outward morphology as a window into the
normally concealed nervous system. We will present our completed analysis of changes in setae patterns
throughout claw transformations and what these changes may reflect in the nervous-system structures
underneath the claws’ surfaces.
40.
Student: Peter Spearman
Major: Biology
Mentor: Kathleen Beres Rogers
Department: Biology
Title: Acute and chronic effects of naproxen and its photodegradants on southern toad
tadpoles
Pharmaceutical pollution is an emerging environmental issue. Many pharmaceuticals pass through
the body, are not completely removed during wastewater treatment, and are ultimately released into the
environment. Naproxen, a widely used pain reliever, has been detected in natural waterways around the
world. When exposed to sunlight, naproxen is converted into two related compounds, known as
photodegradants, which are predicted to be more toxic than naproxen itself. We tested the toxicity of these
three compounds to tadpoles of the southern toad during acute (96 hours) and chronic exposures (until
metamorphosis). Acute toxicity of the first photodegradant was similar to that of naproxen, while the
second photodegradant was over six times as toxic. During chronic exposures at lower concentrations, both
photodegradants reduced tadpole survival and growth, while naproxen had no effect. These results suggest
that the degradation of naproxen in the environment may increase risk to freshwater organisms.
41.
Student: Nicholas G. Taylor
Major: Physics
Title: Nonlinear effects induced by stimuli on the phase resetting curve
Conference: Society for Neuroscience 2013 Annual Conference
Rhythmic patterns of neural activity are ubiquitous phenomena in animals. Central pattern
generators are autonomous networks of neurons that control biological rhythms such as the circadian
rhythm, heartbeats, etc. The neurons change their firing patters due to the inputs from other neurons.
Inputs arrive to the neurons with different amplitudes, durations, and shapes. As a result, each input
induces a different neural response. In these computational experiments, we mimicked injected electrical
stimulus of different amplitude, duration, and shapes into a neuron model. We found that the relationship
between the stimulus strength and the response of the neuron was linear. However, the duration of the
stimulus induced a non-linear response. This suggests that the change in firing rate is not strictly
proportional to the area under the curve of the stimulus, as previously thought, but is also sensitive to other
parameters such as how fast the stimulus reaches its maximum value.
42.
Student: Joshua Teves
Major: Chemistry
Mentor: Mike Larsen
Title: Synthesis of Stereospecific Bis-Indene Catalysts
Everyone recognizes the vital role that medicine plays in our society today. However, not many
people are aware of the difficulties that organic chemists face when making pharmaceutical drugs. It
is often difficult to control certain aspects of a molecule’s structure, specifically its three-dimensional
arrangement. This spatial arrangement of the drug’s structure determines how it will react with the body.
For instance, the anti-inflammatory drug known as Aleve could instead act as a liver toxin if its
three-dimensional shape is slightly different. Our goal is to fabricate a new molecule, also known as a
catalyst, which will aid in making the correctly shaped drug structures. Our newly designed catalyst has been
based off a previous molecule that proved successful. Once we have finished producing our catalyst, we
hope to soon test its effectiveness in making pharmaceutical drugs that require a specific three-dimensional
arrangement.
43.
Student: Travis Varner
Major: Psychology
Title: Developmental Origins of the Moral Sense
Conference: Cognitive Development Society
How do children first learn about, and begin to explore, the moral domain? We hypothesized that
pretend play serves as an important context for moral learning by providing opportunities for moral
evaluation and for moral exploration, as children take on/explore “moral themes.
We studied five children from 2.0 to 5.0-years-old. We coded separately for when they engaged in
pretend play and when morally relevant parent/child dialogue occurred, mapping the extent to which these
two overlapped. While there was a developmental decrease in the frequency of moral dialogue in general,
there was no developmental change in the frequency of moral dialogue within the context of pretend play.
Moral evaluation decreased and exploration increased over time. Children increasingly use pretend play as a
medium through which to explore moral themes, doing so allows for an increased sensitivity to the feelings,
dispositions, and behaviors of those (real/imaginary) with whom they interact.
44.
Student: William Vesely
Major: Biochemistry
Mentor: Vijay M. Vulava
Title: Synthesis of a Novel Dual-Action Cytosporone E/Triazole Antibiotic
Antibiotic resistance is an issue that has recently taken precedence in the medical community and is
rapidly becoming difficult to combat. As more antibiotics are introduced into our water supply, soil, and
food, bacterial resistance to these antibiotics escalates, which reduces the effectiveness of current
commercial antibiotics. The goal of this project is to create a series of new antibiotics, to which bacteria
have not yet grown resistant. To do this we will be combining cytosporone E, a compound shown to have
antibiotic properties, with key features of other antibiotic compounds. These new compounds will then be
tested against different strains of bacteria to determine how effective they are compared to current
antibiotics. The results from these tests will give us insight into how to change and design the next
generation of antibiotic derivatives.
45.
Student: Grace Waddell
Major: Biochemistry
Title: Synthesis of a Novel Dual-Action Cytosporone E/Triazole Antibiotic
Antibiotic resistance is an issue that has recently taken precedence in the medical community and is
rapidly becoming difficult to combat. As more antibiotics are introduced into our water supply, soil, and
food, bacterial resistance to these antibiotics escalates, which reduces the effectiveness of current
commercial antibiotics. The goal of this project is to create a series of new antibiotics, to which bacteria
have not yet grown resistant. To do this we will be combining cytosporone E, a compound shown to have
antibiotic properties, with key features of other antibiotic compounds. These new compounds will then be
tested against different strains of bacteria to determine how effective they are compared to current
antibiotics. The results from these tests will give us insight into how to change and design the next
generation of antibiotic derivatives.
46.
Student: Benjamin Wilson
Mentor: Joe Carson
Title: Extrasolar Planets and Disk Imaging using the Hubble Space Telescope
Conference: 225th American Astronomical Society Conference
The Hubble DICE survey is an observational program approved by NASA. The team consists of
nineteen multinational experts in the field of astrophysics. Led by Dr. Glenn Schneider (Univ Arizona),
there is an ongoing effort to study eleven carefully chosen stars with known circumstellar disks. The
disks surrounding these young stars are interesting because they are believed to be the birthplaces of
planets. By discovering evidence of planet formation in these disks, either by imaging disk gaps caused by
forming planets or by directly imaging the planets themselves, one can gain invaluable insights to guide
planet formation theories and ultimately help better understand the origins of our own solar system.
B. Wilson will be presenting his progress with Hubble DICE and the numerous contributions he
has made in the last year. These contributions include revealing new disk substructures that have not
previously been seen. Attending the conference will therefore be a unique opportunity to present
unmatched progress, achieved at College of Charleston, for interpreting new results from NASA’s flagship
space telescope.
2015 Summer Undergraduate Research with Faculty (SURF)
1. Student: Joyce Biaco
Major: Chemistry
Title: Lewis Acid-Catalyzed Minisci Reactions
Many pharmaceutical drugs contain at least one nitrogen atom. If that nitrogen atom is part of
a ring with carbon atoms it is called a heterocycle. The ability to easily modify a heterocycle is useful to
medicinal chemists because they are then able to create many drug candidates with slightly different
structures and physical properties. We are proposing a method to selectively modify heterocycles that
would be useful for the synthesis of new drug candidates.
2. Student: Paige Bippus
Mentor: Erik Sotka
Department: Biology
Title: Use of herbivory resistance in different populations of the alga Gracilaria vermiculophylla to
track its invasive history
Species that are not native to the habitat they are living in are called ‘invasive species’. Both land
and marine invasive species are changing the community structure (i.e. food webs and competition for
space and nutrients) as well as the surrounding environment. One species of marine seaweed, Gracilaria
vermiculophylla, has invaded virtually all the coasts of the Northern hemisphere. Although we know it
can tolerate a variety of temperatures and salinities, it is believed that the seaweed has adapted
genetically to its surrounding environments in order to thrive. Our object for the project is to
determine whether or not there are genetic differences in the Gverm populations from different regions
of the world that it has invaded. In order to determine genetic adaptation, we must test varying
phenotypes (observable characteristics). The phenotype we will focus on is herbivory resistance. Many
seaweeds, including Gverm, are often unpalatable for various reasons to herbivores that feed on it. In
order to test whether or not populations from different regions have adapted to ward of herbivores, we
will conduct three different feeding experiments in which we feed the Gverm to herbivores and see if
they will eat it or prefer it to local seaweed. By doing this, we will ideally be able to track the invasive
history of the seaweed and discover whether or not it evolved in characteristics that helped it be
successful in many environments. We hope Gverm will serve as a model for analyzing genetic
adaptations of future invasive species.
3. Student: Joseph Boscia
Major: Biochemistry
Mentor: Amy Rogers
Title: Growth and Purification of Endothelial Nitric Oxide Synthesis for Crystallographic Studies
with Novel Pterins Bound
It is not uncommon to hear about molecules that are harmful and should be avoided. But have
you ever heard of a dangerous molecule that you actually need? Nitric oxide (NO), a toxic gas similar
to carbon monoxide, is just that molecule. In fact, it was awarded Molecule of the Year in 1992 for its
surprising role as a neurotransmitter, vasodilator, and anti-cancer agent. So how is this toxic molecule
made in the body with such precision that it provides Dr. Jekyll’s effect and not evil Mr. Hyde’s? The
enzyme nitric oxide synthase (NOS) produces NO in vivo by converting the molecule L-Arginine into Lcitrulline and NO but exactly how this is done is not well understood. There are several cofactors that
are needed by NOS in order for the reaction to proceed; one of them is called tetrahdyrobiopterin
(BH4). Without BH4, the reaction does not proceed and toxic products are formed. But the exact
role of the BH4 is unknown. We believe that one key factor in understanding how NOS produces
NO lies in understanding what BH4 is doing during catalysis. Our studies focus on probing the role
of BH4 by spectroscopic and catalytic assays as well as X-ray crystallography. We believe this important
cofactor provides not only reducing equivalents to the reaction center, but also a proton. Uncovering
the role of BH4 could provide insights into how NOS produces a toxic gas in the perfect concentration
to provide essential biological functions like neurotransmission or cardiac blood flow.
4. Student: F. James Claire, III
Major: Chemistry
Mentor: Kristin Krantzman
Title: Simulations to Study the Morphology of Fullerene-Graphene Nanocomposites
Carbon nanomaterials, such as fullerene and graphene and their derivatives, have attracted
considerable attention for their use in nanoelectronics because of their exciting structural, electronic
and magnetic properties. The excellent electronic and mechanical properties of carbon nanomaterials
enable their use in solar cells, advanced energy conversion and storage devices. Understanding and
controlling the carbon nanocomposite interfacial properties and resulting morphology is a crucial
factor in tailoring materials properties for use in a wide range of applications. The fullerene molecule,
C60, is composed of 60 carbon atoms joined together by single and double bonds to form a hollow
sphere. Graphene is a one-atom thick planar sheet of carbon atoms. It is proposed to use computer
simulations to study the adsorption of fullerene molecules on a graphene solid substrate. The proposed
research will provide a fundamental understanding of the role of physical and chemical properties
of carbon nanomaterials constructed from fullerene and graphene. The results will significantly
enhance the current understanding of the role of surface and component properties on morphology
formation of carbon nanocomposite films and will have direct implications for interpreting
experimental results and can be used as guidelines for design of future nanocomposites.
5. Student: Anna Collett
Major: Biology
Mentor: Jason Vance
Department: Biology
Title: Optomotor response to simulated rotations during tethered flight in honey bees
Honey bees and other insects are capable of rapid maneuvers in response to turbulence and wind
during flight. However, it is unclear how bees detect these perturbations. One possibility is that visual
feedback can provide the sensory input necessary to modulate this rapid kinematic response. Honey
bees' visual system has been well-studied in the context of flight navigation, which contributes to flight
odometry, maintaining heading angle, and flight velocity. However, it is not known how vision is used
over short timescales for reactive flight control. In the proposed research, we will investigate the
reacting time (latency) and frequency response (bandwidth) of the compound eye and ocelli visual
feedback. Bees will be tethered within a custom LED arena, and oscillating visual patterns will be
presented to simulate rotations the yaw-axis. High-speed videography (6000 fps) will record wing and
head movements to characterize the bees' kinematic response. By comparing the bees' kinematic
response to the movement of the visual pattern, we can determine the reaction time and frequency
range of visual feedback on motor control. This research will determine which visual pathways,
compound eyes and/or ocelli, contribute to the initiation and modulation of the kinematic response to
flight perturbations in bees.
6. Student: Patricia Cooney
Major: Biology
Mentor: Christopher Korey
Department: Biology
Title: Mechanisms of Autonomy During Claw Transformation in the Snapping Shrimp
The snapping shrimp, Alpheus angulosus, exhibits a unique characteristic in its front claws. The
snapper, used for defense and communication, and the pincer, used for feeding and habitat
manipulation, differ radically in shape and size. When grabbed by the large snapper claw, the shrimp
will generally drop it in the interest of survival — just as a lizard might drop its tail. Upon dropping
its snapper, the shrimp can “switch hands” by regenerating a pincer from the previous snapper
limb, and transforming the previous pincer into a functional snapper. While this transformation is
standard among snapping shrimp, the specific claw dropping behavior seems to differ within the
species. To evaluate these differences and understand the role of nervous system control in this
process, we have divided a large group of shrimp into categories by sex, size (as a proxy for age) and
molt stage. With these shrimp, we are using a systematic threat process to gauge how long each
shrimp must be threatened before dropping its snapper. After this initial threat, each shrimp will be
given its assigned number of molt stages to develop its new claw before being threatened and
dropping its claw again. With these data, we will be able to further understand the evolutionary
context of snapper dropping behavior, as well as the amount of neural control involved in this
process, forming the groundwork to make this species a competitive model for regenerative
neuroscience studies.
7. Student: Noah Denman
Major: Biology
Title: Quantifying the Sulfatase Activity of SdsA1
The enzyme SdsA1, found in the pathogenic bacterium Pseudomonas aeruginosa, has been proposed
to be capable of degradation of sodium dodecyl sulfate (SDS), a component of soaps and detergents.
Because SDS is a man-made chemical that is not easily biodegradable, SdsA1 might represent a possible
target for the bioremediation of SDS contaminations. However, previous results from our lab showed
that moderate quantities of SDS inhibit the reactions, suggesting that SDS might not be the real
substrate for this enzyme. Here, we are going to study how different chemical compounds that share
some similarities with SDS are degraded by SdsA1, in order to better understand the biological
function of SdsA1.
8. Student: David Derouen
Major: Geology
Mentor: K. Adem Ali
Department: Geology
Title: Satellite Remote Sensing of water quality parameters in the coastal waters of the US Virgin
Islands
Coral reefs in US Virgin Islands (USVI) represent complex and dynamic ecosystems. These
habitats provide primary framework for the development, growth and survival of thousands of species,
and protect shorelines from wave erosion and storm surges. They are highly valuable as a natural
resource, and for ecological services, but yet highly sensitive to changes in surrounding factors
(temperature, water chemistry, and human disturbance). The scenic attributes have drawn more and
more people to this region, and urbanization has increased as a result. This has caused coral reefs to
receive an increased flux of storm water runoff, wastewater discharge, and other contaminants
associated with urbanization. These changes are predicted to accelerate with climate change. Reef
recovery rates are slow and could thus face severe devastation from continued anthropogenic stresses.
A key index that can be used to assess stress on these ecosystems is the water quality. Current water
quality assessment is largely based on in situ measurements with limited spatial and temporal
resolution. This makes it difficult to understand the dynamics of water quality parameters (WQPs)
such as phytoplankton, suspended materials, and dissolved organic matter. Satellite-based synoptic
measurements using multispectral sensors provide better resolution, but require the development of
algorithms that relate spectral reflectance to the WQPs. The goal of the proposed project is to
develop robust regionally tiered model that can estimate concentrations of WQPs from satellite
data in the coastal waters of USVI. These synoptic models can provide information critical to the
understanding of biogeochemical processes in the ecosystem.
9. Student: Diana Devine
Major: Psychology
Mentor: Amy Kolak
Title: Emergent Self-Regulatory Skills Within the Family Context
The primary aim of this research project is to better understand 2-year-old children’s ability to
control their behavior with and without parents’ help. During a visit to our lab, each toddler was
observed in two “don’t touch” tasks. In the first one, the experimenter asked the child not to touch toys
until she returned and the parents, who were both in the room, were asked to reinforce the “don’t
touch” rule. In the second, the child was again asked not to touch a wrapped gift until the experimenter
returned. In this paradigm, the parents, however, were asked not to reinforce the “don’t touch” rule. For
this project, we will apply a coding system to assess the attentional focusing strategies the children used
during these “don’t touch tasks” and examine how these strategies were associated with whether or not
they touched the toys or gift. First, we are interested in examining the difference between children’s
behavior across these paradigms when parents reinforced the rule versus when they did not. Second, we
are interested in examining mothers’ and fathers’ individual parenting and their joint parenting
behavior as relates of children’s behavior in these “don’t touch” tasks. Third, we are interested in
examining longitudinal links between children’s attentional focusing strategies at 2 years of age and
their self-regulation at 5 years of age.
10. Student: Sarina Etheridge
Major: Astrophysics
Mentor: P. Chris Fragile
Title: Contrasting Magnetohydrodynamic Turbulence with Alpha-Viscosity
A black hole accretion disk is an accumulation of materials, such as gas and dust, which orbits a
black hole. The goal of this project is to create two separate computer simulations of black hole
accretion disks. The two computer simulations will use different methods of producing the turbulence
that is required for accretion disks to operate.
One of the simulations will use an artificial viscosity put in “by hand.” This implies that this
method is not a representation of true viscosity, but merely acts like viscosity. No physical mechanism
is truly represented. This is how accretion disks have been modeled for decades. The other simulation
will incorporate the physical process now known to be responsible for accretion, called the magnetorotational instability.
The purpose of the project is to compare the two simulations to understand in what ways the real
physical process differs from the artificial viscosity treatment. Ours will be the first such simulations
done using general relativistic gravity, as is appropriate near a black hole.
11. Student: Lindsay Evans
Majors: Psychology/Computer Science
Mentor: Sorinel Oprisan
Title: Nonlinear effects in time perception modeled with a realistic cortico-striatal network
Time is an essential dimension of the world around us, determining the decisions we make, the
actions we choose to take, and the very precision of our slightest movements. Millisecond timing is
important for speech recognition, auditory processing, playing music and dancing. Circadian timing
(hours to days range) controls sleep and wakefulness, and is critical for metabolic and reproductive
fitness. Interval timing, or timing in the seconds-to-minutes range, is crucial for rate estimation,
decision-making and foraging. Interval timing has been demonstrated in many species, from
invertebrates, to many vertebrates, such as fish and birds, and mammals such as rats and humans. In
most of these species, the error of time estimation varies quasi-linearly with the estimated duration, a
property called scalar property or scalar timing. Deficits in interval timing, including lack of scalar
timing, have been reported in Parkinson’s Disease, Huntington’s Disease, Schizophrenia, Attention
Deficit Hyperactivity Disorder, and Alzheimer’s disease. We will use a realistic computational model
developed by Oprisan and Buhusi (2011) to investigate the effect of the number of neurons allocated to
the interval timing task on the scalar property. The striatal beat frequency (SBF) model produces a
Gaussian output with a sharp peak centered on the learned interval time, as seen in actual experiments,
and, in addition, the output obeys scalar property. The objective of this project is to investigate the
neural network parameters that contribute to nonlinear effects that lead to deviations from scalar
property.
12. Student: Lucas Freeman
Major: Biochemistry
Title: Early Transition Metal Complexes for Carbon-Carbon Bond Formation
The molecules of life are exquisitely complex, a fact which often demands that the chemicals
used to influence biology – drugs, for example, with which we hope to prolong or improve life – have a
very specific structure to give their intended effect. That effect can be finely sensitive to even miniscule
changes in the molecule: switching a single atom’s arrangement can lead to an inactive or even
hazardous drug, as was learned with thalidomide in the 50s. Synthesizing drugs and other useful
organic molecules thus requires very specific control over the reactions in their synthesis. Yet, the
simpler the process to make a drug, and the simpler and more readily available the starting materials,
the more cheaply and more easily the drug may be made for the public. The synthetic chemist
continually looks to more easily build complex molecules: using less energy, using less expensive
materials and simpler methods. Building complex molecules from simple reactants requires control
over how those reactants arrange their bonds and atoms when they combine. The use of a metal
compound – called a catalyst – may provide that control. The goal of this proposed project is to
develop the chemistry of inexpensive titanium (abundant, cheap, non-toxic) catalysts for using simple,
readily available materials to synthesize molecules with control over their complexity. These specific
molecular building blocks can then be further incorporated into desirable, biologically active molecules
such as drugs.
13. Student: Laura Galloway
Major: Biology
Mentors: Agnes Ayme-Southgate
Department: Biology
Jason Vance
Title: Differential gene expression in nurse to forager honeybee transition
Within a honeybee hive, the tasks to be accomplished such as cleaning, feeding, defending and
finding the food are divided between different workers. Most inside-the-hive jobs are accomplished by
the nurses, which barely ever leave the hive and therefore are not active fliers. On the other hand,
finding the food and bringing it back to the colony is the job of the foragers. These are the bees going
back and forth between the hive and the flowers, and therefore, they are extremely good fliers. During
a worker life cycle, the bee starts as a nurse, but at some point becomes a forager, usually based on
the needs of the colony. This process is in a way similar to someone starting a fitness program. So how
do you prepare for such a transition in life? Major changes occur to enable the worker bee to
transition to this completely different job. Decrease in weight, increase in metabolic and immune
activity, and depressed ovary activity are a few of the known reprogramming events. There is also some
evidence for modifications of the muscle proteins to generate enhanced flight ability. Starting to
understand this process at the molecular level is the goal of this proposal. We will use several molecular
biology techniques to investigate the difference in muscle gene expression (usage) between nurses and
foragers. Knowing which muscle proteins are either turned down or overproduced during the
transition will provide a basis for a molecular dissection of this critical process in honeybee life process.
14. Student: Jasmin Graham
Major: Biology
Mentor: Gavin Naylor
Department: Biology
Title: Reconstructing the Evolution of Hammerhead Sharks
Hammerhead sharks are unique among sharks in having a laterally expanded head. Currently, there
are 8 different recognized species of hammerheads. The various species differ, among other things, in
the degree of the lateral expansion seen in the head structure – termed the “cephalofoil”. Two
conflicting hypotheses have been forwarded to account for the evolution of the structure. The first,
based on an assessment of overall form, suggests that the head has become incrementally laterally
expanded over the course of evolution, while the second, based on comparison of mitochondrial DNA
sequence data, suggests that the early forms already had a highly laterally expanded head that became
gradually reduced over time. These two hypotheses invoke opposing directions of natural selection. In
the current study, we propose to obtain nuclear gene data using a cross species gene capture approach
developed in Dr. Naylor’s lab at the College of Charleston that will allow us to address the question
from a genomic perspective.
15. Student: Maja Grzejdziak
Mentors: Merissa Hart Ferrara
Department: Communication
Beth Sundstrom
Title: e-HOPE: Increasing health care access among rural women in South Carolina
Rural populations face unique barriers to health care often resulting in health disparities. Residents
in rural communities are more likely to report poor health status and are less likely to be insured than
their urban counterparts. In 2008, Planned Parenthood of Greater Iowa pioneered the use of
telemedicine by providing health services via sophisticated video and fiber equipment at remote clinics.
Planned Parenthood Health Systems (PPHS) will initiate a telemedicine program (e-HOPE Plus) in
South Carolina in Spring 2015 to address barriers to health care in rural areas, especially in women’s
services. Existing research demonstrated high satisfaction levels among rural participants in a family
health telemedicine project, noting that this method of care offers a promising opportunity in
underserved rural areas.
Over the course of our project, we will work collaboratively with PPHS to evaluate the effectiveness
of the telemedicine program in SC rural communities by conducting a pre-/post-test survey design. We
will seek to determine the impact of the program on patient contraceptive choice, follow-through, and
compliance. This study will expand the limited research regarding the effects of telemedicine as a
promising approach to increase health care access and address health disparities. This research will also
inform the continued implementation of the e-HOPE PLUS project in South Carolina, as well as other
telemedicine projects.
16. Student: Carly Harward
Major: Dance
Mentor: Gretchen McLaine
Department: Dance
Title: Letter to a Man De-constructed: Analyzing choreographic interpretations of mental illness
Choreography is a collaborative art form that exhibits specific themes, ideas, and is often related to
personal experiences of the choreographer. Throughout the planning process it is pertinent that the
choreographer make strategic decisions that will allow the audience to perceive the work in the way
intended. Once the work is complete and presented, the audience is given the freedom to interpret the
piece in the way that they saw it. Because choreography is designed from personal experiences, the
question arises of whether the choreographer can successfully transpose the feelings elicited by one with
mental illness.
“Letter to a Man Deconstructed: Analyzing choreographic interpretations of mental illness” allows
for an intensive look into how mental illness affects creativity and how such illness is communicated
through non-verbal expression. This research project will investigate how mental illness affects both the
messenger and the message in choreographic work. An in-depth analysis of Nijinsky’s journals, on-going
research on creativity and mental illness, and movement analysis via LMA will clarify how Nijinsky’s
illness was perceived by Baryshnikov and expressed through the construction of this new work.
17. Student: Daniel Hickman
Majors: Biology/Chemistry
Mentor: Gamil A. Guirgis
Title: Conformational studies of compounds containing a six-membered ring system consisting of
silicon and other atoms in the cyclic backbone
The proposed project includes the synthesis of four six-membered ring compounds containing three
carbon and three silicon atoms in an alternating fashion. These compounds are not well understood in
the literature because of difficulties in synthesizing, handling, and studying them. These compounds
are interesting and have several possible three-dimensional shapes in space. These compounds can be
studied using different instruments at the College of Charleston and at other institutions. I do have
long standing collaborations in place at the University of Missouri-Kansas City (UMKC) and the
University of Virginia (UVA). The comparison of the data to that of similar known compounds
containing only carbon will reveal the nature of the bonding and structure of these compounds, which
will be useful for potential applications of these species.
18. Student: Mamiko Higa
Mentors: Andrea DeMaria
Departments: Health and Human Performance
Beth Sundstrom
Communication
Rural populations face barriers to health care often resulting in health disparities. Residents in rural
communities are more likely to report poor health status and are less likely to be insured than their
urban counterparts. In 2008, Planned Parenthood of Greater Iowa pioneered the use of telemedicine by
providing health services via sophisticated video and fiber equipment at remote clinics. In South
Carolina, Planned Parenthood Health Systems (PPHS) will initiate a telemedicine program (e-HOPE
Plus) in Spring 2015 to address barriers to health care in rural areas, especially in women’s services.
Researchers found very high satisfaction levels among rural participants in a family health telemedicine
project, noting that this method of care offers a promising opportunity in underserved rural areas.
Over the course of our project, the Women’s Health Research Team will work collaboratively with
PPHS to evaluate the effectiveness of their telemedicine program in SC rural communities by
conducting a pre-/post-test survey design. We will seek to determine the impact of the program on
patient contraceptive choice, follow-through, and compliance. This study will expand the limited
research regarding the effects of telemedicine as a promising approach to increase health care access and
address health disparities. This research will also inform the continued implementation of the e-HOPE
PLUS project in South Carolina, as well as other telemedicine projects nationally and internationally.
19. Student: Lucien Jay
Major: Biochemistry
Title: The Synthesis of Allyl Ureas and Carbamates
Many pharmaceutical drugs contain at least one nitrogen atom. Developing new methods of
incorporating nitrogen into molecules is useful to medicinal chemists. We are proposing a method to
incorporate a nitrogen atom into molecules that can be further modified into compounds with
different properties in a subsequent reaction.
20. Student: Sarah Legendre
Major: Classics
Mentor: Allison Sterrett-Krause
Title: But Is It a Bottle? Quantitative and Qualitative Study of Roman Glass Vessels
Archaeologists analyze fragmentary pieces of antiquity, like broken glass, to answer questions about
aspects of daily life. To do this, archaeologists study “diagnostic” pieces – recognizable parts of
fragmentary glass vessels such as bases, rims, and handles. Such studies record formal characteristics
(shape, size, color, and decoration) and functional categories of the pieces. They then compare the
fragments to objects with similar forms and functions to contextualize individual objects.
Problems arise when vessels are extremely fragmentary and are compounded when fragments share
formal characteristics with many different types of vessels. This is a consistent problem for
archaeologists studying Roman glass of the Imperial period (ca. 50 C.E.to 450 C.E.), because the
Roman glass industry was international and industrial in scale. While formal features of a fragmentary
vessel can reflect its functional category (drinking cup, bottle, plate, etc.), in many cases poor
preservation prevents such precision.
Our current research project will propose a statistical model for determining the functional category
of glass vessel fragments which are not diagnostics. Using the techniques of statistics and probability, we
will test our proposed model for viability on both fragmentary and complete vessels. Our project
employs a contextual component as well: studying glass from ancient perspectives to understand Roman
categories for vessels. Combining quantitative mathematical study with ancient literary and visual
evidence offers a new avenue for archaeologists studying the creation and use of glass in antiquity. Such
a model may provide new methods for archaeologists studying many different time periods and
materials.
21. Student: Needhee Patel
Majors: Biology/Psychology
Mentors: Mike Ruscio
Departments: Psychology
Chris Korey
Biology
Title: Neurogenesis and Neural Development in Snapping Shrimp
The ability of an adult nervous system to change in response to environmental changes, such as
damage to the system, is unique and challenging when scientists are studying vertebrate systems. This is
because to observe a response, permanent damage must often be done to the organism’s nervous system.
Therefore, invertebrates that are known for their regenerative abilities are an ideal system to explore and
study the changes an organism goes through to recover or adapt to its environmental needs. The
snapping shrimp, or Alpheus angulosus, is a small crustacean with two claws, one big and the other small.
If a shrimp loses its big claw, its primary defense, it transforms its small claw into a big claw while
growing a new small claw. The claws have different purposes and thus different sensory neuron inputs
and outputs. We study the neural changes involved in transformation by tracking and studying the
sensory hairs’ (setae) distribution on the claws throughout the duration of this process. Past studies have
revealed that setae change, both in composition and number, mostly on the cutting edge of the claw.
This proposal focuses on the development of the sensory hairs, particularly how and where the sensory
neurons in the sensory hairs are created and how they develop.
22. Student: Olivia Pearce
Major: Chemistry
Mentor: Katherine Mullaugh
Title: Voltammetric Determination of Silver Ions Using Chemically Modified Carbon Paste
Electrodes
Today over 1600 consumer products are available that contain nanomaterials with sizes less than
1/1000 the width of a human hair. As nanotechnology becomes increasingly integrated into daily life,
the release of nanoparticles into the environment is inevitable. To anticipate the potential
environmental effects of nanotechnology, controlled laboratory experiments are required to understand
the conditions that control their behavior in the environment and any chemical changes they may
undergo after release. Silver nanoparticles, currently one of the most widely used types of nanoparticles
because of their antimicrobial properties, are found in products like socks, athletic clothing, and
cleaning products. However, it is now well known that silver nanoparticles readily degrade and release
silver ions, which are toxic to many aquatic organisms. To better anticipate the environmental impact
of silver nanoparticles, more studies are needed to understand the conditions that favor or inhibit the
silver nanoparticle degradation process. Two major limitations of existing studies are (1) that they
generally require high concentrations because the currently available methods of silver ion detection are
not sufficiently sensitive and (2) they require a pre-treatment step to separate silver nanoparticles from
silver ions prior to analysis. The goal of this project is to develop an improved method that is sensitive
enough to measure silver ions at low, environmentally relevant conditions and can measure silver ions
without interference from silver nanoparticles such that no separation is necessary.
23. Student: Dillon Presto
Major: Chemistry
Title: Synthesis and Characterization of Polymer/Graphene Nanocomposites
Solid thin-films composed of mixtures of polymers and carbon-based structures, such as carbon
nanotubes and graphene, are promising materials for the next generation of solar cells and other
renewable energy technologies. One of the main problems is getting the polymer and carbon
structures to interact strongly with each other. Such weak interactions lower the fundamental electrical
properties of these materials, as well as adversely impacting the properties, e.g., ruggedness and
crystallinity, of the solid thin-films. In our lab, we are synthesizing polymer/graphene materials using
an innovative technique, wherein we make the polymer in a solution that already contains the
graphene. We have already shown that this “in situ” polymerization technique improves the
characteristics of polymer/carbon nanotube materials; thus, it is highly likely that we will see same
results with the polymer/graphene counterparts. In addition to making these materials, we are able to
study the surfaces of the polymer/graphene thin-films using an atomic force microscope (AFM). The
atomic force microscope allows us to observe the structure of our materials, e.g., how well they’re
mixed together, on an atomic and molecular level.
24. Student: Ashley Rice
Major: Physics
Mentor: Ana Oprisan
Title: Investigating Non-Equilibrium Fluctuations in the Presence of Magnetic Field
Magnetic nanoparticles are used in many applications, from industry to cancer research. However,
little is known about the mobility of magnetic nanoparticles when used for biomedical applications.
The purpose of this project is to determine physical properties related to the dynamics of magnetic
nanoparticles dispersed in water. We will experimentally investigate fluctuations produced at the
interface between water and magnetic nanoparticles suspensions both in the absence and in the
presence of magnetic field. The nanocolloid consists of tiny spherical particles of iron oxide with
diameters in the range of 100 to 200 nanometers suspended in a water-soluble inert agent. In order to
observe the interface between water and colloidal suspension, the magnetic nanocolloid must have a
relatively high concentration of nanoparticles. Concentration inhomogeneities inside the fluid lead to
local differences in fluid properties. As a result, the interface is not perfectly flat but has microscopic
“bumps” (fluctuations) that can significantly change the speed of the diffusion process. Since, in
addition to temperature and fluid properties, the fluctuations of the interface are strongly influenced
by the concentration of nanoparticles in suspension such interface fluctuations are called concentration
fluctuations. These fluctuations have been so far only investigated in the presence of the gravitational
field. However, our plan is to perform two experiments for the same magnetic colloidal suspension in
the presence and absence of magnetic field.
We plan on recording images of a glass cell unit filled with magnetic nanocolloids that experiences
concentration fluctuations and analyze the images offline. We will use image and data analysis
methods such as Fourier transform, power spectrum, and curve fitting tools to estimate the correlation
time of fluctuations and to determine the diffusion coefficients for both experiments.
25. Student: Amber Ruby
Major: Biology
Mentor: Allison Welch
Department: Biology
Title: Salinity effects on early life stages in squirrel treefrogs
Salinity levels are increasing in some freshwater environments due to human activities including
road salt runoff, land use changes from agriculture, and rising sea levels. Amphibians are particularly
vulnerable to habitat salinization because they need freshwater to complete their life cycle. Increased
salinity can harm amphibian larvae by decreasing survival, reducing growth, and increasing the time to
reach metamorphosis. Salinization of breeding habitats may also affect other stages of the frog life cycle,
including fertilization and embryo development. Exposure to salinity during fertilization could affect
sperm function, decreasing the number of eggs fertilized. Increased salinity can also slow or halt
embryonic development. Testing the salinity tolerance of each of these life stages will help us identify
which life stages are most sensitive to habitat salinization. In addition, we will test how salinity exposure
during fertilization and embryonic development affects tadpole success. One possibility is that early
exposure will allow acclimation to salinity, increasing the ability of tadpoles to survive and thrive at
elevated salinity. On the other hand, early salinity exposure could have a cumulative effect and decrease
a tadpole’s ability to tolerate additional stress from salinity exposure, ultimately leading to poorer
performance or even death. Studying how salinity exposure during early development affects the fitness
of tadpoles will improve our understanding of the effects of habitat salinization during different life
stages. Overall, our work will help conservation efforts address the impact of elevated salinity on the
most susceptible amphibian life stages.
26. Student: Leslie Sawyer
Major: Psychology
Mentor: Chad Galuska
Title: Regulation of Rats’ Water Intake by Shifts in Food Reward Availability
Research in our laboratory has shown that negative incentive shifts involve transitions from
favorable-to-unfavorable situations can disrupt behavior profoundly; these sorts of transitions may have
relevance to the environmental stressors that trigger alcohol seeking in humans. An existing animal
model of negative incentive shifts involves arranging schedules of positive reinforcement differing in
the signaled amount of food pellets delivered contingent upon completing a lever-press response
requirement. The transition from a just-received large food reinforcer to an upcoming signaled small
food reinforcer has been shown to produce profound disruptions in ongoing responding. In the
proposed research, we will use this model to determine if these negative incentive shifts trigger excessive
water consumption (polydipsia) in non-thirsty rats. The resulting data will inform us as to the feasibility
of using this behavioral baseline to induce excessive alcohol consumption in our future research.
27. Student: Sarah Shainker
Mentor: Erik Sotka
Department: Biology
Title: Heat shock, cold shock, and light tolerance of Gracilaria vermiculophylla
Gracilaria vermiculophylla is a red seaweed native to the Sea of Japan and Japan’s northeast Pacific
coast. It has invaded the coasts of North America and Europe. G. vermiculophylla’s successful adaptation
to a wide variety of diverse non-native environments facilitated its successful invasions all over the
Northern Hemisphere. Two adapted traits that have aided G. vermiculophylla’s invasive success are its
ability to tolerate a wide range of temperatures and varying amounts of light exposure. It is unclear
where and when these adaptations occurred. In a pre-adaptation scenario, a subset of the species within
the native range may have evolved to acquire advantageous traits which facilitated biological success
once spread to non-native regions. In a post-adaption scenario, a subset of the native population may
have spread to a non- native area before evolving to acquire advantageous traits after introduction. In a
bridgehead scenario, a subset of the native population would have spread to a non-native bridgehead
location where it evolved to have advantageous traits before further spreading to additional non-native
regions. In order to investigate which scenario or combination of scenarios occurred for G.
vermiculophylla, samples will be collected from native and non-native regions in Japan, North America,
and Europe. The samples will be exposed to different light and temperature ranges and grown in the
lab in order to determine the light and temperature tolerance of samples from various areas.
Comparing these traits in native and non-native individuals could provide helpful information
regarding the evolutionary pathway facilitating G. vermiculophylla’s invasive success.
28. Student: Sierra Raven Small
Mentor: Michael Hemphill
Department: Health and Human Performance
Title: Impact of Imbalanced Community Sex Ratio on Acquisition of HIV and other Sexually
Transmitted Diseases among African-Americans
In 2008, the rate of new HIV diagnoses among adults and adolescents in the United States (US)
was nine times greater among blacks (73.7 diagnoses per 100,000) than among whites (8.2 per 100,000)
(1). This black-white disparity is particularly stark among women. Despite accounting for less than
14.0% of the US female population in 2008 (3), blacks accounted for 66.7% of new HIV diagnoses
among women in 2008 (1). Of women who contracted HIV through heterosexual contact living in
2007, 63.5% were black and 18.6% white, a prevalence ratio of 3.4 (1). Several studies have
hypothesized a link between certain community level factors and the occurrence of HIV among black
women (4, 5-22).
One such community level factor is the community sex ratio, which is defined as the ratio of men to
women in a given geographic area (12). Prior research has shown that sex ratios in predominantly black
areas are substantially more imbalanced (i.e., fewer men than women) than sex ratios in predominantly
white areas (12). The purpose of this project is to assess the impact of the community sex ratio as well as
other demographic variables, including income, education, and racial distribution, on the acquisition of
HIV and other STDs in South Carolina counties. This research will provide greater insight into the
factors that contribute to HIV and STD incidences, and possibly lead to the development of more
effective preventive interventions.
29. Student: Ellie Smith
Mentors: Beth Sundstrom
Departments: Communication
Andrea DeMaria
Health and Human Performance
Rural populations face barriers to health care resulting in critical health disparities and risks.
Residents in rural communities are more likely to report poor health status and are less likely to be
insured compared to urbanized areas. In 2008, Planned Parenthood of Greater Iowa pioneered the use
of telemedicine by providing health services via sophisticated video and fiber equipment at remote
clinics. In South Carolina during Spring 2015, Planned Parenthood Health Systems (PPHS) will launch
a telemedicine program (e-HOPE Plus) to address barriers to health care in rural areas, focusing on
women’s services. Current research shows very high satisfaction levels among rural participants in family
health telemedicine. This method of care presents a promising opportunity in underserved rural areas.
Throughout the duration of our project, we will work collaboratively with PPHS to evaluate the
efficacy of their telemedicine program in South Carolina’s rural communities by conducting a pre-/post
test survey design. As a team, we will investigate how the program influences patient contraceptive
choice, follow-through, and compliance. This study will contribute to the limited research regarding the
effects of telemedicine in order to increase health care access, while addressing health disparities. This
research will also ensure the successful implementation of the e-HOPE PLUS project in South Carolina,
as well as telemedicine projects pertinent to communities nationally and globally.
30. Student: Heather Thornton
Major: Studio Art
Mentor: Sara Frankel
Department: Studio Art
Title: Contemporary Apotheosis: A Vision Explored in Painting
The dynamic theme of humankind’s quest for spiritual meaning is found not only in art history
but in the history of humanity. Today there are newfound methods of searching for personal spiritual
significance outside of conventional religions relating to science and the perspective of humanity as an
integral component of the universe. Translated through a body of five large-scale oil paintings,
Heather Thornton will explore this theme employing a contemporary approach and the guidance of
her faculty mentor Professor Frankel. Heather’s visual conception, in which figures commingle with
heavenly objects and otherworldly spaces is inspired by both fantasy and cosmic imagery. With an
emphasis on glowing light emanating from their hearts, hands and minds, each figure in the
paintings will resonate a universal energy and awareness.
Utilizing a professional painting process and practice with the academic critique of Professor
Frankel, the artwork will achieve a level of fantastic realism and will be suitable for display in
professional gallery settings.
31. Student: Travis Varner
Major: Biochemistry
Title: Synthetic and Theoretical Studies of a Novel Bis-Indenyl Ligand: The “Batwing”
Everyone is familiar with different everyday polymers, such as Styrofoam and spandex. In the
production of some polymers, a molecule called a catalyst is often needed to start the reaction to
produce a specific polymer. Designing these catalytic systems has received much attention over the
years, in hopes that they can be used to also control other vital aspects of the desired polymer. One of
these certain features of interest is the three-dimensional arrangement of a polymer’s structure. This
simple spatial arrangement can completely change the properties of a product polymer molecule.
Therefore, it is vital for a chemist to be able to control this aspect when designing and synthesizing new
materials. Certain catalysts have been seen to possess this unique feature of regulation—nonetheless,
there is still the need for more exploration of this topic. Using current known catalysts as models, a new
“batwing” catalyst has been designed and synthesized. We are seeking funding to support research that
involves the synthesis and computer modeling of this original metal catalyst.
32. Student: William Vesely
Major: Environmental Geology
Mentors: Timothy Callahan
Department: Geology
Vijay Vulava
Title: Organic carbon concentrations and dynamics in estuaries and associated watersheds
Dissolved organic carbon (DOC) is a classification for carbon dissolved in aqueous environments.
DOC is increasing in estuaries, which are bodies of water where freshwater combines with tidal waters
from the ocean resulting in conditions that can support a wide variety of habitats, such as certain
species of fish (red drum) and shellfish (oyster, crab). The most common source of DOC in the
estuaries is phytoplankton. The non-estuarine sources of DOC are terrestrial plant debris and
freshwater plankton arriving from river flow. An intriguing non- estuarine source, and what will be a
focus for this project, is the submarine flow of groundwater. This research will produce a survey of
DOC concentrations in surface waters and shallow groundwater in coastal South Carolina.
Water samples will be taken from locations in the Ashepoo, Combahee, and Edisto (ACE) Basin
and Charleston harbor. Samples will also be taken in regions located further inland to see DOC
content in a forested area. The data will be used look at the DOC differences between a forested areas
and urbanized areas. The main goal of this project is to better understand the amount of DOC in the
ACE Basin and Charleston regions. As land use is changed for housing development, less groundwater
may be cycling through these systems and thus a source of carbon to the estuaries, relied upon by the
aquatic food web, may be impacted.
33. Student: Alexis Violette
Major: Chemistry
Mentor: Neal Tonks, Jr.
Title: Drug Delivery Polyurethane Materials Using Bio-Based Polyols
Polyurethanes are widely used polymer materials that have applications from paint coatings to
soft/rigid foams. More recently, polyurethanes are being developed for drug delivery purposes. By
incorporating a drug-delivery pre-polymer into the polyurethane matrix, we can produce a material
that will slowly release a drug under physiological conditions. There are two significant unique aspects
this project. Firstly, only biologically compatible materials will be used. Almost all current polymeric
polyurethane materials are made using chemicals derived from petrochemicals. The major material in
the final product by mass consists of a polyalcohol derived from a soy-based edible oil. Secondly,
new drugs that have never been used for drug delivery purposes before using polymer delivery systems
are being investigated. For this study, a series of successful drug delivery materials were made from the
anti-inflammatory drug Ibuprofen, nalidixic acid, a simple antibiotic compound as well as two potent
chemotherapeutic agents. Upon exposing these drug delivery materials to physiological media,
significant drug release was observed in as little as 20 hours. A library of synthetic
methodologies for the prodrugs was developed by Nathan Adamson over the last year and a half. The
project will continue this summer, specifically by exploring new synthetic approaches to these
polymeric materials to yield products with varying applications including type of drugs being released,
rate of drug release, and overall composition of the material. In addition, long-term degradation studies
of these materials will be performed to confirm their safety in biological environments, and the results
will be monitored by LC-MS.
34. Student: Hannah Wilson
Major: Biology
Mentor: Joe Carson
Title: An Innovative System for 3D Clinical Photography
We recently developed a low-cost, user-friendly technique to take a single snapshot image using the
commercially available Lytro camera and convert this image into a full 3D rendering that can be
effective for the diagnostic monitoring of cancer lesions, such as AIDS- induced Kaposi’s sarcoma – the
leading cancer among men in Mozambique. By utilizing a relatively low cost (~$200) consumer camera
as the technology backbone, the technique translates to an estimated cost of around 75 cents per
diagnosis. This is an extreme benefit for areas of the world that cannot afford most 3D imaging
technology that is available today. In contrast, for example, the commonly used Magnetic Resonance
Imaging (MRI) has a typical cost of >$2,000 per diagnosis, as well as requiring expert personnel to
operate it and substantial infrastructure to support it. Our technology provides a way for minimally
trained personnel to operate it, and the complicated data processing work can take place at a location
away from the resource limited setting, allowing relevant results to be succinctly summarized and
restored to clinicians in the field. To prove the effectiveness of the technique, we and collaborators
successfully carried out a pilot program at Maputo Central Hospital, the largest public hospital in
Mozambique, and showed that effective, single-snapshot, 3D images of Kaposi’s sarcoma lesions could
be obtained bedside by minimally trained personnel. The results are published in the Journal of
Translational Medicine (Baghdadchi et al. 2014).
APPENDIX F Abstracts 27th Annual Poster Session ‐ Thursday, April 16th 2015 The first fourteen posters are featured as part of the UNESCO International Year of Light. Each has a light‐based connection. 1. Video Analysis of Reef Fishes and Live Bottom Seafloor Cover in the South Atlantic Bight Luke Rein1, Gorka Sancho1, Rachel Bassett1, Tracey Smart2 and Dawn Glasgow2 1 Department of Biology, College of Charleston, 2 South Carolina Department of Natural Resources South Carolina Department of Natural Resources’ Marine Resource Monitoring, Assessment and Prediction Program (MARMAP) collects and analyzes data concerning the South Atlantic Bight’s commercially important snapper‐grouper fishery to determine catch limits and conserve the region’s fishery. In addition to conventional trap capture‐based data, MARMAP increasingly employs video recordings to determine key metrics about the fish communities in this region. This study uses video analysis to compare the presence of live bottom seafloor cover to the abundance and diversity of four common species of the snapper‐grouper complex (C. striata, P. pagrus, R. aurorubens, and B. capriscus). This analysis shows that live bottom seafloor cover may have a variable effect on the presence of fishes. 2. Correlating solubility parameters and Kamlet‐Taft solvatochromic parameters with the self‐
assembly of poly(3‐hexylthiophene) in mixtures of organic solvents Madeline P. Gordon and David S. Boucher, Department of Chemistry and Biochemistry Recent experimental endeavors have shown that well‐ordered P3HT assemblies formed in solution can improve the crystallinity and morphological uniformity of thin films and composites, thereby providing a promising new route to more efficient polymeric optoelectronic materials. We have studied the assembly and crystallinity of poly(3‐
hexylthiophene) (P3HT) in >100 binary solvent mixtures using UV‐Vis absorption spectroscopy, APPENDIX F and it is clear that the identity of the poor solvent used to drive aggregation has a significant impact on the structural order and crystallinity of the P3HT aggregates in solution. Here we report our findings using Hansen solubility parameters (HSPs), specifically the solubility distance vector, Ra, and the Kamlet‐Taft solvatochromic parameters of the solvent mixtures to better understand the dominant solvent forces driving the self assembly of P3HT. 3. Direct imaging of concentration‐induced fluctuations in nanocolloids Lincoln Fraley, Department of Physics and Astronomy Nanocolloids are ideal systems for investigating both spatial and temporal processes using optical methods since they have particle sizes larger than the characteristic size of atomic or molecular systems. We performed direct imaging experiments in order to investigate the concentration‐driven non‐equilibrium fluctuations. Our direct imaging experimental setup involved a glass cell filled with colloidal suspension and water with the concentration gradient oriented against the gravitational field and a superluminescent diode (SLD) as the light source. Nonequilibrium concentration‐driven fluctuations in silver nanocolloidal suspensions with a range of particle sizes and at different concentrations were recorded using direct imaging technique. We used a dynamic structure factor algorithm for image processing in order to compute the structure factor and to find the power law exponents and the correlation time of these fluctuations. The investigation of time evolution of concentration induced fluctuations allowed us to evaluate the dynamics of critical wave number. 4. Palagonite Alteration of the Blue Dragon Flow, Craters of the Moon National Monument, Idaho Garth Groshans Jr. and Robert Nusbaum, Department of Geology and Environmental Geosciences The purpose of this research was to study surficial weathering and alteration products of the Blue Dragon lava flow located in Craters of the Moon National Park, Idaho. Of particular interest is the alteration of basaltic glass to palagonite in a terrestrial setting. Palagonitization of Blue Dragon Lava is observed as dark brown alteration product surrounding plagioclase and olivine phenocrysts within the basaltic glass. Lava samples were analyzed using polarized light microscopy and a Tescan MIRA‐3 SBU scanning electron microscope (SEM) equipped with a backscattered electron detector and an energy‐dispersive x‐ray spectrometer (EDS). Backscatter SEM images suggest the palagonite is compositionally zoned distal from the phenocryst boundary. While glass values for elemental oxides are relatively constant, the same oxides may vary by a factor of five in adjacent palagonite. With the exception of MgO, the results are consistent with initial development of amorphous “gel” palagonite described in the literature. 5. Toxicity of combinations of Naproxen and its Photodegradants APPENDIX F Luke Rein1, Allison Welch1 and Wendy Cory2 1 Department of Biology 2 Department of Chemistry and Biochemistry Pharmaceutical compounds have been observed in natural waterways, due largely to their incomplete removal from wastewater. In the environment, ultraviolet radiation can degrade these pharmaceuticals into other biologically active compounds. However, continual input of common pharmaceuticals results in pseudopersistence, whereby enough new material is added that levels remain elevated in spite of their breakdown. We investigated the effects of UV photodegradation and pseudopersistence on the toxicity of naproxen, a common anti‐
inflammatory. Southern toad tadpoles were exposed to naproxen, its two UV degradants, and combinations of these three compounds in proportions that correspond to laboratory observations of naproxen photodegradation. Naproxen’s two degradants were significantly more toxic than naproxen itself, and combinations of naproxen and its photodegradants were particularly toxic. These data suggest that the ecological effects of pharmaceutical pollutants may be underestimated. 6. An Innovate System for 3D Clinical Photography Hannah Wilson and Joseph Carson, Department of Physics and Astronomy We and collaborators have developed a novel imaging technique that enables 3D imaging from a single digital snapshot, for the purposes of low‐cost clinical photography in resource limited settings, such as rural regions in southeast Africa. The technique takes advantage of the emerging technology of light‐field photography, which captures the information of multiple focus depths in a single digital snapshot. Our novel software approach reconstructs 3D shapes by evaluating how different parts of the image sharpen or blur at different focal depths. We combined our computational approach with a commercially available light‐field camera, Lytro, and a medical hardware adaptor custom‐developed by collaborators to ensure controlled and repeatable measurements. We have recently been working to expand our capabilities to enable endoscopic imaging with a miniaturized camera version as well as to improve the overall accuracy of our 3D rendering technique. 7. Pericyte Distribution in the Cerebral Cortex Revealed by High‐Resolution Imaging of Transgenic Mice Ian Grant, David Hartmann, Robert Underly, Ashley Watson, Volkhard Lindner, and Andy Shih, Department of Biology and Program in Neuroscience, College of Charleston, Department of Neurosciences, Medical University of South Carolina, and Center for Molecular Medicine, Maine Medical Center Research Institute Pericytes are essential for normal brain function and play diverse roles in the brain, including maintenance of blood‐brain barrier integrity, angiogenesis, and regulation of cerebral blood APPENDIX F flow. Defects in pericyte function facilitate tissue injury in stroke and neurodegeneration by impairing cerebral microcirculation and vascular stability. Here, we utilized a transgenic mouse line that expresses Cre constitutively under the PDGRFβ promoter, providing highly specific and near complete labeling of pericytes along the entire cerebrovasculature. Optically cleared brain tissue from these animals allowed for collection of high‐resolution image stacks over the entire depth of cortex using two‐photon microscopy. Analysis of pericyte distribution in cleared tissue was assessed between layer I and layer II/III of the cortex, which revealed marked differences. Further characterization of pericyte density in other in vivo‐accessible brain regions will provide insight to overarching pericyte distribution, and may lead to discoveries that implicate varying pericyte distribution in certain disease pathologies. 8. Relationship between Population Growth and Land‐cover Change in the Charleston Area: A Landsat Remote Sensing Study from 1984‐2014 Zak Bartholomew, Shelby Bowden, Eric Brown, Carolina Cardoso, David Derouen, Sam Fink, TJ Gladden, Elliot Harrington, Kristin Hughes, Robert Jones, Kori Ktona, Will Lorentzen, Savannah Norvell, Griffin Scott, Elizabeth Watkins, Hannah Yates, and John Chadwick, Department of Geology and Environmental Geosciences The Charleston area is one of the fastest growing metropolitan areas in the eastern U.S., with Charleston, Berkeley, and Dorchester Counties increasing their total populations by 54.4% between 1980‐2010. The relationship between population growth and changes in land cover (i.e. loss of natural vegetation and gain of human‐modified cover like concrete and asphalt) can be monitored in the region using satellite remote sensing. Five student teams analyzed a total of 20 multispectral Landsat Thematic Mapper images collected between 1984 and 2014 using ENVI image processing software to quantify land cover changes. Image pixels were classified as vegetation, marsh, or urban development (other minor cover types were unclassified), based on their unique spectral reflectance properties. The results show that urban land cover increased by 117.5 km2 (16.8%), vegetation decreased by 108 km2 (8.7%), and marsh increased by 11.4 km2 (5.1 %) over the 30‐year time span. 9. Searching for Extrasolar Planets with the Subaru SEEDS Survey Kellen Lawson, Nathan Gunzenhauser, Laura Stevens, Joe Carson, Department of Physics and Astronomy, and the multi‐national SEEDS Science Team We present a status report on the SEEDS subprogram to search for extrasolar planets (exoplanets) around high‐mass stars. SEEDS, the Strategic Exploration of Exoplanets and Disks with Subaru, is a multi‐year, direct‐imaging survey to explore the link between planets and disks, and the evolution of protoplanetary systems and debris disks. It is an international project approved by National Astronomical Observatory of Japan (NAOJ) and led by PI M. Tamura. With first observations carried out in 2009, the high‐mass star subprogram uses the Subaru 8‐meter Telescope, an adaptive optics system (AO188), the HiCIAO near‐infrared imaging science camera, and the angular differential imaging (ADI) technique, to search for heat APPENDIX F signatures from young exoplanets. The survey is currently in its concluding stages. We describe the selection of our 42 targets, observing and data processing procedures, and recent progress and results. 10. Quantifying Coastal Changes of Cape Romain, SC using Google Earth from 1989 to 2014 Kristin Hughes, Kori Ktona and Leslie Sautter, Department of Geology and Environmental Sciences Cape Romain is a prominent cuspate foreland on the South Carolina coast, located approximately 35 miles north of Charleston. A thorough study using Google Earth imagery was completed in order to determine the geomorphologic changes of the shoreline from 1989 to 2014. Major factors that have affected the shape of Cape Romain include storm surges and hurricanes. Qualitative data were analyzed from historical imagery, and quantitative analyses of shoreline changes were made using Google Earth measurement tools. This study is crucial for use in managing the National Wildlife Refuge located on Cape Romain, and for understanding the effects of the cuspate foreland's changing morphology on the nearby barrier islands. 11. Engineering a Photodegradation Protective Coating for Firefighter Turnout Gear Isaac Gould, Yeon Kim, Shonali Nazare and Rick Daivs, National Institute of Standards and Technology In a study done in 2011 it was found that firefighter suits, comprised of melamine polymer blend, are particular susceptible to mechanical degradation from to UV radiation. This degradation severely limits the suits potential lifetime use. To increase the suits lifetime a thin photoprotective film of TiO2 nanoparticles was applied to the melamine fabric and then tested for its effectiveness in improving the fabrics mechanical performance after advanced UV exposure. 12. Exploring 3D data acquisition, modeling, and printing for geoscience applications Kyle W. Bostick and Norman S. Levine, Department of Geology and Environmental Geosciences Geoscience 3D visualization and modeling has become relevant with the advent of laser‐
scanning, drone and 3D printing technologies. This project explores several methods for 3D data acquisition: laser‐scanning and "photo‐stitching" (sample modeling) and eBee drone and LiDAR data (landscapes). Real‐life objects (e.g., fossils, specimens) and terrains were imaged and converted into polygonal mesh composed of vertices, edges, and faces. These geometric data collectively define the shape of a polyhedral object; when coupled with 3D management software such as MeshMixer we can modify shape, size, fill, and textures. Using our "MakerBot 5.0" 3D‐printer, we have produced several scale‐models of geologic terrains as well as completed paleontological models including an ocular orbit for Xenorophid whale skull on display at the Mace Brown Museum of Natural History. There are numerous applications of APPENDIX F these 3D imaging technologies which include the curations of specimens, illustrating data for visually impaired students, and the manufacture educational flood‐models. 13. Art Installation Visualizing Rogue Wave Modeling Victoria Shuler and Annalisa Calini, Department of Mathematics Rogue waves are waves of extreme height that can appear out of nowhere, at times in a calm ocean, and have been known to cause many a shipwreck. Only recently, systematic measurements from oil platforms and from satellites have shown that rogue waves are far more common than expected. This artwork is a representative visitation for several concepts concerning a mathematical model of rogue wave formation in deep water. The model is based on the Nonlinear Schroedinger Equation, that admits rogue wave‐like solutions, and that give rise to chaotic dynamics when physically realistic corrections are added. The underlying mathematical theory that this artwork denotes shows that a chaotic sea state enhances rogue wave generations, providing a possible explanation of why rogue waves are not such rare events. 14. The Design and Testing of a Raindrop Velocimeter Derek R. Tuck and Michael L. Larsen, Department of Physics an Astronomy Using affordable laser diodes and photodetecting transducers, a simple instrument was constructed. This instrument is designed to be capable of measuring raindrop arrival times at two locations with known vertical offset. Acquired data includes the fall speeds of large raindrops with the ultimate goal of identifying and analyzing drops falling slower than their terminal velocities. Here we present results from the early calibration and testing phases of the instrument prototyping process. 15. Bathymetric and Geomorphologic Characterization of the Mouth of Shannon, Ireland Victoria Houston and Leslie Sautter, Department of Geology and Environmental Geosciences The Shannon Estuary is located on the west coast of Ireland where Ireland’s longest river, the River Shannon enters the Atlantic Ocean. In July 2011, the Marine Institute of Ireland surveyed the 15 km wide estuary mouth between Loop Head and Kerry Head. Data were collected aboard the Institute’s R/V Celtic Voyager using a Kongsberg EM3002 multibeam echo sounder and were processed using CARIS HIPS & SIPS 8.1 to map the basin’s geomorphology. Marine development opportunities and sheltered deep‐water add ecological and economical value to the Shannon Estuary. This study characterizes the seafloor of the southern portion of the estuary mouth, using bathymetric data and revealed a significantly large area potentially consisting of bedrock buried under soft mud extending to both edges of the mouth at approximately 20 meters. Creating a slope map, reveals steep edges, inferred as rocky outcrops. APPENDIX F 16. A Role for the Extracellular Matrix Protease ADAMTS5 in Cardiovascular Development Lockett Nelson1, Sarah Thibaudeau2 and Christine B. Kern2 1 Biology Department 2 Department of Regenerative Medicine and Cell Biology, Medical University of South Carolina (Intentionally blank) 17. Phase resetting of neural oscillators subject to multiple inputs Kelsey Vollmer and Sorinel Oprisan, Department of Physics and Astronomy External stimuli, such as presynaptic inputs, reset the phase of neural oscillators. The phase resetting curve (PRC) determines the advance or delay of an action potential based on the strength and timing of the presynaptic stimulus. Since neural oscillators are nonlinear systems, the neural response to a set of external stimuli is not the sum of responses to an individual stimulus. We developed a systematic and consistent mathematical approach to predicting the phase resetting induced by multiple stimuli that arrive during the same activity cycle of a neural oscillator. Our approach is independent of oscillator’s biophysical details and generalizes the single‐stimulus PRC. 18. Effect of burning regimes on ants in a longleaf pine forest Olivia LaRussa and Brian Scholtens, Department of Biology In Francis Marion National Forest, fire regimes combat the invasion of loblolly pine and preserve the longleaf pine ecosystem. However, this treatment affects other organisms in the forest. Ants range in their ability to withstand hot, xeric conditions; therefore, forest fire management may influence which species can survive. Samples were taken at four different soil types in corresponding maintained and unmaintained plots of the forest. The arthropods collected were sorted to morphospecies and the ants identified to genus or species. The predominant species in both treatments was Nylanderia parvula. ANOVAs comparing the number of ants sampled or diversity indices between treatments showed no significant differences. However, collections were made using Winkler funnels for extraction and recent research has indicated that pitfall traps may be a more appropriate sampling technique in temperate areas. Further experimentation using this method may illustrate how fire adapted genera like Solenopsis are affected by fire maintenance. 19. Computational Studies of Hemodynamic Flows in Abdominal Aortic Aneurysms Danielle Massé and Jason Howell, Department of Mathematics Biomedical research has recently indicated that some specific dynamic characteristics, such as the blood wall shear stress and oscillatory shear index, of the blood flow inside arteries with APPENDIX F aneurysms are risk factors for both the enlargement and rupture of the associated aneurysm. The primary objective of the project is to determine the influence that the geometry of an abdominal aortic aneurysm has on these specific characteristics. 20. Protein Disulfide Isomerase as a Novel Drug Target in ER+ Breast Cancer Chelsea Snipes and Danyelle Townsend, College of Charleston Department of Biology and Medical University of South Carolina Department of Pharmaceutical and Biomedical Sciences Protein disulfide isomerase (PDI) is a chaperone protein in the endoplasmic reticulum that facilitates folding and disulfide bond formation in its protein substrate. Estrogen receptor alpha (ERα), a steroid hormone receptor and transcription factor, directly interacts with PDI. The posttranslational modification, S‐gluthathionlylation, prompted by oxidative stress, inhibits PDI‐
ERα interaction suggesting that redox regulation of PDI mediates ERα stability. Using Kaplan‐
Meier Plotter, this introductory study examined the overall survival probability in silico of breast cancer patients expressing high and low levels of protein disulfide isomerase A1 (PDIA1) between disease subtypes and treatments. High levels of PDIA1 are shown to be a poor prognostic factor in estrogen receptor positive breast cancers and therefore a novel drug target with the potential to dually target estrogenic signaling and protein homeostasis. 21. Behavioral Evidence for Enhanced Intracellular Calcium Signaling in Cocaine Sensitization Carrie Bailes, Bethany Pavlinchak, Arthur Riegel and William Buchta, College of Charleston Department of Biology and Program in Neuroscience and the Medical University of South Carolina Department of Neuroscience Chronic cocaine use causes cellular adaptations in the prefrontal cortex (PFC) that contribute to addiction and relapse. A better understanding of these cellular adaptations will promote the development of effective relapse pharmacotherapies. Chronic cocaine disrupts multiple intracellular signaling cascades in the PFC, including calcium release from intracellular stores. However, the behavioral role for intracellular calcium signaling in addictive behaviors is unclear. Therefore, using cocaine sensitization to model aspects of addiction, we designed experiments to test the hypothesis that an elevated release of calcium from PFC stores contributes to cocaine sensitization. To establish behavioral sensitization, we administered daily cocaine (15mg/kg IP) to rats and assessed their locomotor responses. In sensitized animals, pharmacological manipulation of calcium release from intracellular stores augmented locomotor activity in sensitized animals but had no effect in non‐sensitized animals. These findings demonstrate that adaptations in intracellular calcium signaling within the PFC contribute to the expression of cocaine sensitization. 22. Topsoil: An Open Source Visualization Tool for Geochronologists Ben Wilson, Brandon Wagner, Cortney Mood, Tom Evans, Paul Kyser and Jordan Burrows, Computer Science Department APPENDIX F We are StackOverflow, a group of six Software Engineering Practicum students at the College of Charleston. Our semester long project has been to contribute to the open‐source project, Topsoil. Topsoil is an open‐source visualization tool for geochronologists. Topsoil has been developed by the CIRDLES undergraduate research lab, by principal investigator Dr. Jim Bowring. As Topsoil approaches a major release this summer, we have been aiding in the development of documentation and refactoring the existing code base in preparation for the upcoming version. 23. MuseScore: a free and open source way to create, play and print sheet music Eugene Johnson, Trevor Kirkpatrick, Philip Rabe, Frank DuRant, Department of Computer Science MuseScore takes the concept of open source and applies it to both the development of the software and to the sharing of products produced by the software. It includes a highly sophisticated social aspect integrated into the web platform, which enables MuseScore users to share sheet music files easily and efficiently. MuseScore is written primarily in C++ and is used to create, play and print sheet music, and is supported on Windows, OSX and several Linux operating systems. MuseScore can be used for a variety of purposes, including the writing of personal pieces to entire orchestral arrangements. Musescore is released under the GNU General Public License agreement. Its source code is made publicly available through its repository on GitHub. 24. Erroneous Drop Sizing by Impact Disdrometers: Possible Effects on Z‐R Relationships Kate O'Dell and Michael L. Larsen, Department of Physics and Astronomy Erroneous drop sizing by impact disdrometers and its effect on the relationship between rain rate (R) and reflectivity factor of RADAR (Z) was investigated using data inferred from a two‐
dimensional video disdrometer. Six events were studied in detail. Comparison of drop size distributions for the inferred impact disdrometer data and the two dimensional video disdrometer data revealed substantial differences in drop sizing. However Z‐R relationships produced using each set of data showed minimal effects of erroneous drop sizing. 25. General Relativistic Radiation Hydrodynamic and Magnetohydrodynamic Simulations of Low‐ Angular Momentum, Super‐Eddington Accretion onto Black Holes Ally Olejar, Department of Physics and Astronomy We use the state‐of‐the‐art, astrophysics numerical code Cosmos++ to gain insight into black holes and black hole accretion disks. For this project, we investigated the black hole accretion disk systems which exceeded the Eddington Limit, the maximum luminosity an astronomical object can have while maintaining hydrostatic equilibrium. Astronomers have observed objects (particularly black hole systems) which exceed this luminosity, which suggests that the APPENDIX F proposed Eddington Limit may not restrict nature at all. In order to accurately treat the radiation physics of these systems, we have included Compton cooling into Cosmos++ and have performed several tests to ensure the high performance of the code. 26. Age and Length Structure of Tomtate Haemulon aurolineatum in a Marine Protected Area Zachary Brooker, Tracey Smart2, Rachel Bassett1 and Gorka Sancho1 1 College of Charleston 2 South Carolina Department of Natural Resources This study aims to provide contemporary data for the age and length structures of tomtate (Haemulon aurolineatum). A total of 1,251 fish were sampled from May 2000 to September 2014 by the South Carolina Department of Natural Resources (SCDNR) near deep‐water reefs in Marine Protected Areas (MPAs) along the coasts of North and South Carolina. Total (TL), standard (SL), and fork lengths (FL) were recorded for 1,249 fish to the nearest millimeter, and total fish weight (W) was recorded to the nearest gram. Ages were recorded for 737 of 1,251 samples. Samples were sexed using macroscopic observation in the lab on the research vessel. Growth curves, meristic conversions between lengths and weights, and age composition are essential data inputs to stock assessment models used most commonly in the southeastern United States, and those from this specific study can potentially be used in a new management plan for the Tomtate fishery. 27. A Comparative Dietary Analysis of Haemulon aurolineatum and Haemulon plumierii Mary Frances Babrowicz, Kevin Spanik, Rachel Bassett and Gorka Sancho, Department of Biology A diet analysis can provide insight on competition for resources, food web dynamics, and transfer of energy through the ecosystem. Species population management is most effective when focusing on ecosystem based fisheries management. Studying groups of fishes rather than one species can be useful when completing a dietary analysis of the community. This study compared the diet of two species from the genus Haemulon: Tomtate, Haemulon aurolineatum, and White grunt, Haemulon plumierii. Both species had a widespread diet that included amphipods, bony fishes, bryozoans, crabs, decapods, echinoderms, gastropods, isopods, mollusks, ostracods, shrimp, sponges, stomatopods, tunicates and worms. White Grunt had a more diverse diet, feeding on a total of 52 varied prey items, while Tomtate fed on 21 different prey items. Competition between the two fish is unlikely because of the wide variety of prey items consumed. 28. Hello, Girl ‐ Promoting Computer Science Through the Sugar Learning Platform Joye Nettles, Alex Castelli, Sarah Mackey and Alex Housand, Department of Computer Science APPENDIX F A worldwide effort to provide every child with opportunities towards quality education, the Sugar Learning Platform is humanitarian free and open source software that promotes "collaborative learning" for users through a number of Sugar Activities. Adding to Sugar’s immense collection, Hello, Girl is an activity that encourages young girls to learn programming using fashion to create a customized girl. With this activity, users would simply drag and drop various clothes and accessories on the doll of their choice. As they do this, the users will also be able to learn how the python commands associated with the dolls appearance would be modified. Hello, Girl was developed in the Sugarizer development environment using Javascript and CSS. Moving forward, community participation is encouraged in future iterations of this activity. It is our hope that Hello, Girl will be another step towards breaking down the male‐
dominated stereotypes of the computer science field. 29. Slumps in a Proposed Marine Protected Area on Florida’s Atlantic Margin Luke Rein and Leslie Sautter, Department of Geology and Environmental Geosciences A proposed network of marine protected areas (MPAs) off the east coast of the United States has undergone multibeam sonar surveillance to determine the major seafloor features in the region. One particular site, located approximately 130 km east of Jacksonville, Florida on the shelf margin, possesses a number of slump features that may provide habitat for fishes in the snapper‐grouper complex that the MPA is intended to protect. The slumps at this survey site were analyzed to determine a relationship between slump width and slump relief, and it was found that in most cases, slumps exhibit greater relief as they increase in width. 30. Toxicological Effects of Oil Dispersants Finasol OSR 52 and Corexit 9500 on the Eastern Mud Snail, Ilyanassa obsoleta Millie Thomas and Marie DeLorenzo, Biology Department The explosion of the Deepwater Horizon offshore oil drilling rig in 2010 brought a discharge of oil into the ocean of a magnitude not previously seen. This necessitated the use of many different means of oil spill remediation, includingoil dispersants such as Finasol OSR 52 and Corexit 9500. With little research previously done on these chemicals, it is of great importance that the effects of these dispersants are better understood as to more effectively and safely clean up oil spills. The Eastern Mud Snail, Ilyanassa obsoleta, is an ideal estuarine species to study the effects of these chemicals on as it lives and feeds benthically in estuaries from Canada to Northern Florida. This study determined the LC50 values of the two dispersants on larval and adult mud snails, and determined that larval and adult snails are more sensitive to Finasol than Corexit, with larval snails showing greater sensitivity than adults. 31. Chronic Intermittent Ethanol Exposure Alters Protein Expression in the Lateral Orbitofrontal Cortex APPENDIX F Julia Moss1,2, Natalie McGuier2, Joachim Uys3 and Patrick Mulholland2,4 1 Department of Biology and Program in Neuroscience 2 MUSC Department of Neuroscience 3 MUSC Department of Pharmacology 4 MUSC Department of Psychiatry and Behavioral Sciences Alcohol use disorders (AUDs) are chronic, relapsing conditions characterized by excessive alcohol consumption and various behavioral deficits. Research in chronically drinking individuals shows functional deficits in the orbitofrontal cortex (OFC). A recent study from our lab demonstrated an increase in the density of long, thin dendritic spines in the lateral OFC (lOFC) following withdrawal from chronic intermittent ethanol (CIE) treatment. We hypothesized changes in synaptic protein expression would accompany this alteration and performed a proteomics analysis to compare expression in the post‐synaptic density of neurons in the lOFC of CIE‐treated mice versus unexposed controls. CIE treatment altered 29 proteins and immunoblotting confirmed changes in growth associated protein‐43, elongation factor 1, synaptopodin, α actinin, and excitatory amino acid transporter‐2. Protein‐level changes affect morphological remodeling and glutamatergic signaling; together, these physiological processes may underlie OFC‐dependent behavioral deficits observed in AUD patients. 32. You Can’t Monitor A Volcano If You Don’t Know What Time It Is Carolina D. Cardoso and Steven C. Jaumé, Department of Geology and Environmental Sciences Beginning on September 23, 2004, earthquake activity increased within Mount St. Helens, which culminated in an eruption on October 11. We acquired data from seismic stations close to Mt St Helens from the Incorporated Research Institutions for Seismology Data Management Center (IRIS DMC). We attempted to use this data to locate and track seismic sources within Mt St Helens in the lead up to the eruption. Unfortunately, after some analysis, we determined the data was corrupted. We expected P‐waves to always arrive at station SEP before station YEL; we found, however, that for some events this was reversed. A detailed examination of data from SEP and YEL revealed time gaps and overlaps ranging from 0.086 to 0.899 seconds in the seismograms. This leads to mislocations of seismic events by up to 2 km. We are in the process of reporting this problem to the IRIS DMC. 33. Dynamic Modeling of Targeted and Non‐Targeted Advertising Strategies Chloe Fletcher and Jason Howell, Department of Mathematics With the growing collection of data regarding the depth of detailed knowledge of consumer habits and trends, firms are gaining the capability to discern customers of other firms from the market of uncommitted consumers. Firms with this capability will be able to implement advertising campaigns where the advertising effort towards customers of competing firms differs from that towards uncommitted customers. We develop two mathematical models for APPENDIX F the dynamic behavior of sales due to competitive advertising in a setting with a small number of competing firms. One model (non‐targeted) assumes the advertising effort is the same for both categories of customers, and the other model (targeted) gives firms the capability to allocate advertising effort across the two categories differently. The models are mathematically analyzed and we formulate and answer several strategic questions that a firm may face when implementing a targeted policy. 34. CHRONI ‐ An Android Application for geochronologists to access archived sample analyses from the NSF‐funded GeoChron.org data repository Joye Nettles and Jim Bowring, Department of Computer Science Today, geochronologists are archiving their data and results to public cloud archives managed by the NSF‐funded GeoChron database. The software application ET_Redux developed by Dr. Bowring at the College of Charleston provides seamless connectivity to GeoChron for geochronologists to automatically upload and retrieve their data. CHRONI is a mobile application for Android devices that provides easy access to this information. With CHRONI, geochronologists can view archived data and analyses downloaded from the Geochron database, or any other location, in a customizable format. CHRONI uses special documents called Report Settings to create the customized data display on a mobile device. In addition to providing geologists effortless mobile access to archived data and analyses, CHRONI allows users to manage their GeoChron credentials, download private and public files, and view specialized graphics associated with particular files. Future versions of CHRONI will be developed to support iOS compatible (iPhone, iPad, and iPod) devices. 35. Analyses of Marine Protected Areas on the North Carolina Continental Shelf Lisa Diamond, Department of Biology and Leslie R. Sautter, Department of Geology and Environmental Geosciences Along the southeastern coast of the United States, oceanic and conservation organizations have joined forces to enact Marine Protected Areas (MPAs) with varying geographic locations, sizes, and management types in order to benefit focal species and their critical habitats. Two MPAs in North Carolina, located off the coast of Frying Pan Shoals and Cape Lookout Shoals, were evaluated through the analysis of their seafloor features and biology. In June 2014, NOAA geoscientists collected multibeam sonar data from aboard NOAA Ship Nancy Foster. This bathymetric information provided insight to the seafloor features found at each MPA. Additionally, NOAA provided underwater images from a remotely operated vehicle (ROV) in these areas. Images showed presence/absence of the focal species near these protected and managed zones. Seafloor features and biota present were analyzed together to assess each MPA’s influence on the focal species’ abundances. 36. Behavioral Neuroscience in the Snapping Shrimp, Alpheus angulosus: An Autotomization Study APPENDIX F Patricia Cooney, Melissa Hughes and Chris Korey, Department of Biology The snapping shrimp, Alpheus angulosus, exhibits a unique characteristic in its front claws. The snapper, used for defense and communication, and the pincer, used for feeding and habitat manipulation, differ radically in shape and size. When grabbed by the large snapper claw, the shrimp will generally drop, or autotomize, it in the interest of survival—just as a lizard might drop its tail. Upon autotomization, the shrimp can "switch hands" by regenerating a pincer from the previous snapper limb, and transforming the previous pincer into a functional snapper. While this transformation is standard among snapping shrimp, the specific autotomy behavior seems to differ within the species. To evaluate these differences and understand the role of nervous system control in this process, we have begun a large‐scale behavioral analysis in which we compare drop latency of shrimp by sex and size initially, and by stage in claw transformation after initial autotomy. 37. Searching for Emission Episode Self Consistency in Gamma‐Ray Burst Light Curves Thomas Cannon and Jon Hakkila, Department of Physics and Astronomy Using light curves of gamma‐ray bursts (GRBs) detected by the Burst And Transient Source Experiment on NASA’s Compton Gamma Ray Observatory, we introduce a new method of self‐
consistent GRB categorization. We compile a table of similarity distances measuring the degree of correlation between any two GRB light curves. We then apply automated data mining tools such as Self‐Organizing Maps and decision trees to sort like‐GRBs into groups according to their similarity distances. The results give us an additional method for classifying GRB light curves. 38. Role of Programmed Cell Death in Complement Mediated Killing of Candida Species Beatrice Zaki1,2, Mary Alice Cummings1,2, Silvia Vaena de Avalos2 and Caroline Westwater2,3 1 Department of BIology, College of Charleston 2 Department of Oral Health Sciences, Medical University of South Carolina 3 Department of Microbiology and Immunology, Medical University of South Carolina Candida species are the most common fungal pathogen of humans. Our laboratory has discovered that complement‐derived peptides prompt potent antifungal activity against Candida glabrata. The goal of this study was to examine whether cells display classic markers of programmed cell death in response to complement peptide exposure. Phosphatidylserine is a phospholipid membrane component that is held on the cytosolic side of the cell membrane by the flippase enzyme. The triggering of cell death allows phosphatidylserine to flip to the extracellular side, becoming a signal to macrophages to engulf the cell. Cell death may also be triggered by DNA damage, and is accompanied by the production of excessive reactive oxygen species. Therefore, this study measured the appearance of programmed cell death markers in complement peptide treated cells by monitoring intracellular reactive oxygen species, the APPENDIX F appearance of phosphatidylserine and annexin in the outer membrane, and the degradation of DNA. 39. Gender Determination and Reproductive Development of the American Eel, Anguilla rostrata, in Southeast North American Waters M. Austin Sturkie, Department of Biology The American eel, Anguilla rostrata, is a catadromous species found throughout the waters of eastern North America. A histological verification of gross gender assessment and reproductive development in the species provided a unique opportunity to compare findings in southern waters to previous studies, all of which so far have been performed in or north of Chesapeake Bay. All specimens studied were caught in inshore waters of South Carolina. A relationship was found between fish length and maximum oocyte size, while measurements of mean and extremes in oocyte size were found to be in disagreement to all past studies performed in more northerly waters, likely due to differences in environment sampled and the reproductive strategy of the animal itself. 40. Introduction of FT‐IR and 19FNMR Protein Probes via SNAr Brenna Norton‐Baker, Jessica Kapp, Carson Reed and Marcello Forconi, Department of Chemistry and Biochemistry The electronic environment of proteins is highly idiosyncratic. IR and NMR spectroscopy are commonly used to reveal information about the properties of local environments. Proteins lack nitrile groups and fluorine atoms, making these good candidates for selective probes. Taking advantage of the nucleophilicity of cysteine, we developed a facile, inexpensive way to modify this amino acid and introduce such probes via nucleophilic aromatic substitution (SNAr). We found that N‐ and O‐protected cysteines react with a variety of fluoroaromatics, including 3,4,5‐
trifluorobenzonitrile (TFBN). FT‐IR analyses showed that the nitrile stretching frequency of the cysteine‐fluorobenzonitrile is dependent on the solvent electronic properties, lending to the proposal that it will indicate electronic properties of protein microenvironment. Protein modification trials were conducted using lysozyme, BSA, and hemoglobin. Analysis of the TFNB‐
treated proteins through Ellman’s reagent and mass spectrometry analysis suggests that solvent‐exposed cysteine residues of these proteins were modified by TFBN. 41. Slope Failure Potentiality within the New England Seamount Chain: Analyzing Bathymetric Profiles for Potential Submarine Landslides Garth Groshans and Leslie Sautter, Department of Geology and Environmental Geosciences The New England Seamount Chain (NESC) is a deep sea volcanic chain comprised of over 30 volcanic peaks. These seamounts developed from the Great Meteor mantle‐plume hotspot between 100 and 80 million years ago, and extend over 1200 kilometers in the northwest APPENDIX F Atlantic Ocean. Seamounts of the NESC exemplify eminently steep terrain that could potentially have hazardous implications if submarine landslides were to result. The Gulf Stream current coinciding with steep topography can possibly expedite erosional processes. In addition, the entire NESC is capped with a thin layer of sediment on top of basaltic rock, which can contribute to further instability. At the utmost, severe slope failure could produce a cataclysmic tsunami event on the prone shores of Bermuda or New England. Cross‐sectional profiles allow for quantifiable comparisons of seamounts based on calculations of slope and hydrostatic pressure. Seamounts exhibiting definitive guyot morphology posed the highest feasibility for slope failure. 42. Geomorphology of the Continental Margin off of the Dingle Peninsula, Ireland Hannah Yates, Leslie Sautter and Erin Beutel, Department of Geology and Environmental Geosciences From May to June 2009, the R/V Celtic Voyager collected multibeam bathymetric data off the southwest coast of County Kerry, Ireland for The Geological Survey of Ireland and Marine Institute. The system used for data collection was a Kongsberg EM3002 system. CARIS HIPS and SIPS 8.1 software was used to post‐process the data and create 2D and 3D bathymetric surfaces. The area of study is located within Dingle Bay and immediately south of the Blasket Islands where the seafloor ranges from a depth of 20 to 100 m. The various features studied within Dingle Bay (outcrops, joint systems, and folds) show compressional forces acting both NW‐SE and NE‐SW, representing the Caledonian and Variscan Orogenies, respectively. The main deformational event that has shaped the geomorphology of Dingle Bay appears to be the Caledonian orogeny in the late Cambrian to mid‐Devonian. Best of Chemistry & Biochemistry and Solubility Parameters for Polymers Best of Mathematics 43. Convex Benjamin Stephens, Department of Chemistry and Biochemistry Solubility parameters are certain measurable quantities that are observed to influence the ability of a solvent to fully dissolve a polymer. Current theory indicates that the dispersion energy, the dipole interaction, and the hydrogen bonding of the material are of critical importance, and each material has coordinates in a three‐dimensional parameter space. The Hansen Solubility Parameters of a polymer are taken to be the center of the sphere of best fit of the coordinates of the good solvents in the parameter space. We propose a new method APPENDIX F computing solubility parameters of a polymer that employs the convex hull of the good solvents in the parameter space and describe several alternatives for the computation of the convex solubility parameters of that polymer. 44. Histological analysis of adipose tissue in the tail of American alligators exposed to tributyltin in ovo Nolan Barrett, Department of Biology Tributyltin (TBT), a chemical used as an antifouling agent, gained attention after studies linked TBT‐exposure to imposex in gastropods and obesogenic properties in mammals by stimulating the PPARγ‐RXRα heterodimer signaling pathway. The developmental and obesogenic effects of TBT have not been investigated on Alligator mississippiensis (American alligator). At developmental stage‐19, the collected eggs were given a single dose of 0.5 µl /g egg weight ethanol, 0.2 µg /g egg weight TBT, or 0.625 μg /g egg weight rosiglitazone. At one‐week‐old, the alligators were euthanized and necropsied. In a comparison between hatchlings' and one‐week‐
olds' morphometric measurements, the regression of the tail girth index in the TBT‐exposed group was significantly higher as compared to the control group. The tail adipose tissue was histologically analyzed to evaluate morphological alterations such as the number of adipocytes. The results showed that there were no significant changes in the number of adipocytes across the treatments. 45. Investigation of Structural Plasticity Elicited by Cocaine within the Prefrontal Cortex of Rats Steven Lander1,2, Ben M. Siemsen2, Patrick Mulholland2, Jonathan Koerber2, Peter Kalivas2 and Jacqueline F. McGinty2 1 Department of Biology 2 Department of Neuroscience, Medical University of South Carolina Pre‐clinical models of cocaine self‐administration (SA) suggest dysregulation of the dorsomedial prefrontal cortex (dmPFC) to the nucleus‐accumbens core (NAc) initiating relapse to drug‐
seeking. We have previously shown that cocaine SA decreases phospho‐protein signaling in the dmPFC two hours after the final SA session, suggesting a reduction in synaptic transmission and shrinkage of dendritic spines. The present study investigated whether cocaine SA alters apical spine head diameter and density in the dmPFC during the two‐hour timepoint. Rats self‐
administered cocaine for 14 days then were perfused two hours after the final session; brain slices containing the dmPFC were cut. Images of individual apical dendrites were then taken from layers V and II/III. Preliminary data indicates that cocaine SA decreases apical II/III spine density and decreases spine head diameters of layer V pyramidal neurons. We predict that this APPENDIX F alteration plays a role in facilitating relapse due to decreases in synaptic activity during early withdrawal. 46. Ranking Coaches To Help Predict March Madness Steve Gorman, Department of Mathematics Despite there being many different types of predictive models to create brackets for March Madness, most don't take into consideration the value of a good coach. In order to take this into account, a simple method of evaluating and quantifying the strength of a coach was developed, called "Coach Ratings". This poster will discuss the creation of Coach Ratings in addition to it's effectiveness at picking out potential upset years and building a better March Madness bracket. 47. Heme Analysis by Liquid Chromatography‐Mass Spectrometry Nicholas J. Harris, Elizabeth H. Blankenship and Jennifer L. Fox, Department of Chemistry and Biochemistry Heme is an essential cofactor required for function of the mitochondrial electron transport chain (ETC). The protein complexes of the mitochondrial ETC utilize heme cofactors with different functional group modifications of the porphyrin ring, designated heme A, B, and C. To analyze the heme content of mitochondria, we sought to develop a sensitive and reproducible method using liquid chromatography‐mass spectrometry. Challenges included the need to avoid the use of trifluoroacetic acid, the low solubility of heme at low pH, and adapting literature heme extraction and liquid chromatography methods designed for use with visible absorbance detection to the mass spectrometer. 48. Analysis of Amino Acid Residues Essential for Function of Heme A Synthase Nicholas G. Taylor, Nicholas J. Harris, Oleh Khalimonchuk and Jennifer L. Fox, Department of Chemistry and Biochemistry and University of Nebraska Department of Biochemistry Heme A is an essential cofactor required for function of the mitochondrial electron transport chain. This cofactor enables electron transfer within cytochrome c oxidase to reduce molecular oxygen to water and to help establish the protonmotive force needed to drive ATP synthesis. The heme A cofactor is synthesized from heme B precursor by the successive actions of the heme O and heme A synthases, which respectively incorporate a farnesyl and aldehyde modification to the porphyrin ring. However, the enzymatic mechanisms of these biosynthetic processes remain debated, and recent discoveries suggest additional roles for the heme A synthase. We investigated this enzyme by expressing mutants in the eukaryotic model organism Saccharomyces cerevisiae and determined the effects of mutations on enzyme structure and function. APPENDIX F 49. Lumican Emerges as a Potential Regulator of Cardiomyocyte Hypertrophy Using a Developmental Approach Lorna Doucette, Loren Dupuis, Matthew Berger, Samuel Feldman, Shukti Chakravarti, Amy Bradshaw and Christine B. Kern, Biology Department The maturation of cardiomyocytes and the extracellular matrix (ECM) occurs simultaneously in postnatal development. Collagen assembly is required to maintain a healthy mature heart but not all patients with collagen‐related disorders have mutations in genes directly related to collagen. The role of the small leucine rich proteoglycan (SLRP), lumican that binds to collagen is investigated here. Lumican was immunolocalized in the cardiac ventricles beginning at E10.5. A significant number of mice homozygous for the lumican gene (C57BL/6) died at postnatal day 0 and had increased ventricular myocardium. There was no significant increase in proliferation at E17.5, E18.5 or P0. However the myocardial cell size at P0, 1 month, and 4 months was significantly increased in lumican null mice compared to wild type littermates, suggesting myocardial cell hypertrophy had occurred. These data propose that lumican may play a critical role in the maturation of ECM which controls eutrophic growth of cardiomyocytes. 50. Mopidy Laura Barber, Cameron Beacham, Michael Blackburn and Ron Zielaznicki, Department of Computer Science Music has slowly become more and more integrated into our lives as technology grows. Originally, music was static, meaning it only came from one source, but now, music can be from streaming services like Spotify, Pandora, Soundcloud, etc. or local files on whatever device is playing the music. This makes it much trickier to get access to all of your music at once. Mopidy solves this issue by separating the client from the backend controlling your music. This makes your music library extensible and allows you to aggregate all your music sources into one. Additionally, Mopidy uses MPD clients that take Mopidy’s content and delivers it to the device you are using in the format you want. This poster will show our teams contributions to the Mopidy open source project. 51. Opening Apache Open Office Logan Minnix, Erik Engstrom, Kenneth Startin, Patrick Lynn and Nicholas Bechtol, Department of Computer Science Apache OpenOffice is an open source productivity suite. As a team, we have joined the community and have contributed to the project by fixing bugs, improving documentation, and adding features. This involved downloading and installing the source code for OpenOffice, getting it running, and also being able to run and debug the code in our Eclipse IDE. The first bug fixed dealt with differentiating between two shades of blue that had been misrepresented in the color palette. The second entailed removing links to older search engines that were no APPENDIX F longer in use. The third bug was much more involved. The word count function in the Writer module was malfunctioning and needed to be fixed. In our fourth and final bug, we added a new feature to the Writer module. We added shortcut keys to quickly increase the font size of a selected text segment. 52. Using Confounder Correcting Orthogonal Projections to Latent Structures (ccO‐PLS) to classify high‐dimensional data sets with small sample sizes David Moore and Paul Anderson, Department of Computer Science Predicting biological phenotypes from next‐generation high‐throughput data sources is essential to bioinformatics. However, confounding variables such as gender, age, and habitat can skew the results of such data, leading to biased and inaccurate results. While work has already been done to create a confounder correcting method in Support Vector Machines by Li et. al, there is no such method available for a classification algorithm suited for high‐
dimensional data sets with small sample sizes (d >> n). We have extended Li et. al’s confounder correcting algorithm for Support Vector Machines (ccSVM) to allow Orthogonal Projections to Latent Structures (O‐PLS) to account for confounding variables. We demonstrate that our novel method improves the accuracy of a non‐confounder correcting O‐PLS implementation, and that it is better suited to datasets that exhibit the d >> n pattern than the ccSVM. 53. The Effects of Cocaine on Cue‐induced Drug Seeking Leading to Relapse Mallory Mulvaney, Sade Spencer, Constanza Garcia‐Keller, Doug Roberts‐Wolfe and Peter Kalivas, College of Charleston Department of Psychology and Program in Neuroscience and the Medical University of South Carolina Department of Neurosciences Chronic cocaine usage induces an increase in nucleus accumbens core (NAc) medium spiny neuron (MSN) spine head diameter. These changes, designated as transient synaptic potentiations (t‐SP), occur at variable times during reinstatement. The longer latency in expected t‐SP allowed us to hypothesize that cocaine‐priming suppresses the initial t‐SP. Rats were trained to self‐administer cocaine paired with cues for 10 days. Following extinction, a modified reinstatement schedule was imposed where the rat was exposed to 10 min of cues with no cocaine access followed by 45 min with access. Rats were sacrificed at various intervals to demonstrate that upon access, the increase seen in MSN spine head diameter is reversed. This reaffirms that cocaine promotes an increase in dopamine release in the NAc, thus removal of this access increases drug seeking behaviors. This research is pertinent to finding a treatment for addiction as the reinstatement schedule resembles the human phenomenon “relapse”. 54. Comparison of Salt Withdrawn Basins on the Louisiana Continental Shelf, Northern Gulf of Mexico Megan Jackson and Leslie R. Sautter, Department of Geology and Environmental Geosciences APPENDIX F Multibeam sonar data of submarine basins were analyzed along the continental shelf in the Northern Gulf of Mexico, an area known for its numerous salt domes (diapirs). The sonar data were collected in 2014 using a Kongsberg EM302 abroad the NOAA Ship Okeanos Explorer. Three areas of the region off the Louisiana coast were studied and consist of diapirs and several small basins, referred to as salt withdrawn basins. Depths of these basins were measured along with each basin’s short and long axes. A comparison of the axis ratios to basin depths showed depth does not affect the basin shape. Several of the basins measured were nearly circular with varying depths. Backscatter intensity analysis was performed on three basins of varying depths and showed no relationship between basin bottom hardness and basin depth. 55. Geochemical Fate and Transport of Antidepressants in Natural Soils William C. Vesely, Larissa R. Almeida, Ashleigh N. Kirker and Vijay M. Vulava, Department of Geology Unintended exposure to antidepressant medications have become a worldwide concern due to increasing presence in water resources. They are discharged from wastewater treatment plants in trace levels resulting in soil, sediment, and groundwater contamination. Trace levels of three antidepressants: fluoxetine (Prozac), sertraline (Zoloft), and bupropion (Wellbutrin) have been reported in natural streams. The main objective of this study was to determine sorption and transport behavior of these antidepressants in natural soils. Sorption and transport experiments were conducted using two types of natural soils – organic rich A‐horizon and clay‐
rich B‐horizon soils. The antidepressants were measured using UV‐Vis and HPLC techniques. Sorption isotherms were nonlinear and fit using Freundlich model. The data showed fluoxetine and sertraline sorbed more strongly to the B‐horizon soil while bupropion sorbed more strongly to A‐horizon soil. Fluoxetine and sertraline preferentially sorbed with negatively‐charged clay minerals in B‐horizon soils. Bupropion sorption behavior suggests partitioning into organic‐rich A‐horizon soils. 56. The impact of P3HT molecular weight and solvent composition on P3HT films processed from binary solvent mixtures Lawson T. Lloyd, Madeline P. Gordon and David S. Boucher, Department of Chemistry and Biochemistry Polymer assembly and organization into well‐defined nanostructures is of great interest for organic photovoltaic applications. We have studied the assembly and crystallinity of two regio‐
regular poly(3‐hexylthiophene) (P3HT) samples, Mn » 28 kDa and Mn » 65 kDa, in several different binary mixtures of organic solvents. We use an excitonic coupling analysis of the UV/Vis absorbance spectra to assess the impact that the solvent and the molecular weight of P3HT have on the relative structural order of the polymer assemblies. In addition, we investigate the influence that the solvent composition and the structural order of P3HT aggregates have on the assembly and organization of P3HT films. We use optical and atomic force microscopy techniques to study thin films of P3HT processed from different solvent APPENDIX F mixtures. Our results show that relatively small variations to the P3HT solutions can produce significant changes in the morphology and macromolecular structures of the P3HT films. Best of Physics and Astronomy 57. Diurnal Evolution of the Statistical Structure of Near Surface Wind Alexis Payne and Mike Larsen, Department of Physics and Astronomy Near surface wind’s power spectrum was studied with a focus on how it shifts through a diurnal cycle. Data were acquired using three sonic anemometers to gather wind speed and temperature. For each of the 26 days studied, the data were partitioned into four disjoint six hour intervals. It was apparent that wind’s power spectrum does go through a diurnal shift. However, the transition still preserves statistical structure. Nevertheless, small changes were evident in the power law exponents, for sunrise it was ‐1.64±0.06, for day it was ‐1.68±0.02,for sunset it was ‐1.47±0.15, and night’s was ‐1.33±0.07. 58. Wreck this Calculus Book Kaitlyn Manley and Amy Langville, Department of Mathematics Many students are frustrated by their Calculus textbooks, finding them to be dry, formulaic, and uninteresting. These students end up memorizing definitions for tests, without ever learning how to appreciate the conceptualizations behind the polished texts. These students will often ask, "Why do we need to learn Calculus?" or "How is this useful to me?" Professor Langville started writing her "Wreck this Calculus Book" series with the goal of instructing students in a way that they can understand the "traces of investigation" made by the discoverers of calculus. Using hands‐on activities, challenge and conceptual problems, graphic novellas, pictures and diagrams, and stories of the history of mathematics, the "Wreck this Calculus Book" series has flourished, with five potential works in progress, including two nearly‐
complete books covering Calculus 1 and Calculus 3. This poster will show examples of the types of activities and pages in her books, and explain why books like these are needed. 59. Bathymetric Analysis of Axial Seamount's Southeastern Flank, Juan De Fuca Ridge Anna DeGeorge and Leslie Sautter, Department of Geology and Environmental Geosciences APPENDIX F Multibeam sonar data were acquired aboard the R/V Thomas G. Thompson. Axial’s southeastern flank exhibits a unique topography that is a direct result of the geological implications and processes associated with extrusive eruptions and seismic activity. Through this study, we found that the flank is characterized by terraced lava flows. The feature has layers that extend from the caldera to the base and all vary in depth ranging from ~1450 to 2500 meters. The second area studied was a cluster of small seamounts located at the base of the flank. The seamounts sit in a linear pattern and all have the same general morphology. These six seamounts range in depth from ~2400 to 2500 meters. Backscatter analysis showed that the shorter seamounts are primarily composed of hard rock, most likely basalt, and the taller seamounts are composed of soft substrate, most likely sand, mud, and silt deposited on the seafloor. 60. Extending deep neural networks to multi‐way classification Kellan Fluette and Paul Anderson, Department of Data Science Deep learning models that capture high‐level abstractions in data often outperform standard models for classification problems. On large datasets, significant gains in classification accuracy can be achieved by using computationally efficient non‐linear transforms, such as using deep neural networks (DNNs) or stacked denoising autoencoders (SDAEs), to model higher‐level abstractions in the data before using standard models for classification on the transformed dataset. Le et al. have developed Fastfood, a method for approximating kernel expansions in loglinear time; kernel expansions are performed in neural networks and must be calculated for every pair of training samples–this quickly becomes costly for large datasets, and is partially resolved by using Fastfood kernel expansions. As the existing paper describes using Fastfood optimized neural networks (FONNs) for binary classification problems, we extend the algorithm such that it can be applied to classification problems with more than two classes using a logistic classifier. Best of Computer Science 61. Galaxy Classification Using Deep Belief Networks Alexander Jacobs and Paul Anderson, Department of Computer Science The massive number of galaxies in the universe poses a central problem for astronomers and requires novel techniques to be used for classification. To cope with the vast amounts of data created by modern observations, past research organizations, specifically Galaxy Zoo (part of the citizen science project, Zooniverse), have crowd‐sourced morphological classification APPENDIX F techniques, inviting members of the public to log onto a website and classify the data. The technique has been effective, but we hypothesize that we should be able to apply machine learning techniques to classify the data as well as humans. We analyze the performance on this classification task for a deep learning neural network constructed by stacking restricted Boltzmann machines on top of one another, also referred to as a deep belief network. 62. The Roles of MMPs and nNOS in Animal Models of Heroin Reinstatement Emily Berich, Alexander Smith and Peter Kalivas, Department of Psychology and Program in Neuroscience, College of Charleston, and Department of Neuroscience, Medical University of South Carolina Proteins necessary for the neuronal plasticity that characterizes addiction include matrix metalloproteinases (MMPs) and neuronal nitric oxide synthase (nNOS). We explored the effect of pharmacologically inhibiting MMP‐9 and nNOS in a brain region critical to addiction, the nucleus accumbens (NA), on reinstatement behavior and MMP activity. Following heroin self‐
administration, rats received intra‐accumbens injections of either MMP or nNOS inhibitor prior to reinstatement, a quantifiable model of heroin relapse. Behavior analysis revealed that MMP‐
9 inhibitor attenuated reinstatement‐associated level pressing, (p=0.2659), suggesting MMP‐9 is necessary for heroin relapse. Furthermore, in vivo zymography data suggested that microinjections of nNOS inhibitor, but not MMP‐9 inhibitor, led to lower levels of MMP activity than contralateral microinjection of vehicle (t4=3.692, p=0.021), indicating that nNOS is necessary for the MMP upregulation associated with heroin reinstatement. These data implicate an important role for MMP‐9 and nNOS in neuronal plasticity related to heroin relapse. 63. Are You a MAHT Person? MAHT, a novel genomic approach to study the stability of human tRNAs. Ariel McShane, Eveline Hok, Jensen Tomberlin and Renaud Geslain, Laboratory of tRNA Biology, Department of Biology Genetic translation is the universal mechanism that allows the biosynthesis of cellular proteins; some of the most prominent actors in this process are transfer RNAs. Paradoxically, little is known about the stability of individual tRNA species because of the practical challenges that represent precise and systematic tRNA identification. This work describes a new technical and conceptual in vivo approach named MAHT (Microarray Analysis of Human tRNAs) designed to study the stability of human tRNA at the genomic level. The overall half‐life for the entire pool of human tRNAs was estimated at 43 hours, suggesting that most tRNAs are passed down from parent to daughter cell during cell cycle. Interestingly, five tRNAs, specific to Leu, Gly, Glu, Pro and His amino acids were found to be significantly less stable. The role of posttranscriptional modifications on tRNA stability is currently under investigation. APPENDIX F 64. How noise influences the interval timing clock Derek Novo1, Sorinel Oprisan1 and Catalin Buhusi2 1 Department of Physics and Astronomy 2 Department of Psychology, Utah State The ability to accurately and reliably estimate the passage of time in the supra‐seconds range (interval timing), is critical for cognitive processes like decision making, rate calculation, and planning. A timed response in this temporal range typically follows a Gauss‐like curve centered at the time being estimated (criterion time) and with a standard deviation proportional to the criterion time. We used a computational model that mimics the activity of some neurobiological structures known to be involved in interval timing. In our model, the output of the network is determined by the coincidence between the state of the network at the reinforcement time and the current activity. We found that small fluctuations of the network’s parameters have specific signatures that allow us to identify the source of noise. 65. Graphical User Interface for Beets Derek Novo, Andrew Hanold, Jason Houston and Carter Wooten, Department of Computer Science Beets is a free and open source music organizer that aims to give the user exceptional control over manipulating and accessing his or her music library by utilizing metadata. Beets catalogs the user’s music collection and improves its metadata upon continual use by exploiting the MusicBrainz database. Before this work, the user was required to evoke Beets’ functionality via command line operations. We are currently implementing a workable Graphical User Interface (GUI) for both novice users and an overall more intuitive experience. Here, we discuss the requirements analysis involved in developing this GUI. Specifically, we examine the requirements analysis involved in designing the import function, which moves music to the user’s desired directory. Since this function can be customized with a tag suite on the command line, we aim to retain this flexibility in our GUI. 66. Blockade of Stress Related Neuropeptides Reduces Binge‐Like Drinking in Male C57BL/6J Mice Clark Phelps, Rachel Anderson, Marcelo Lopez and Howard Becker, College of Charleston Department of Biology, Charleston Alcohol Research Center, Department of Psychiatry and Behavioral Sciences‐Medical University of South Carolina and Ralph H. Johnson Veterans Administration Medical Center Alcohol abuse is one of the most preventable health problems facing society. Mouse models are useful for testing drugs that may reduce excessive alcohol consumption. In this experiment we examined the effects of two drugs that have been recently shown to play a large role in APPENDIX F stress modulated drinking, a κ‐opioid receptor (KOR) antagonist and a corticotropin releasing factor (CRF) antagonist on binge‐like drinking using the drinking in the dark model (DID). In the DID model the mice were given access to alcohol for 2 hours for 3 consecutive days, followed by a 4th test day when we administered the drug prior to 4 hours of access to alcohol. We also tested both drugs with sucrose drinking and activity monitoring boxes to see if they were selective for alcohol. KOR antagonists appear to be a great candidate to treat excessive alcohol consumption, while CRF antagonists appear to have nonselective effects. 67. Comparison of Effectiveness of Convolutional Neural Networks Daniel Hurlburt and Paul Anderson, Data Science/Computer Science Department There has been a great push in recent years to allow computers to make sense of the vast amounts of data which exist around us. Tasks of allowing computers to make meaningful associations and classifications are becoming increasingly important, and great strides have been made in recognition tasks because of advancements in convolutional neural networks, which perform recognition by using overlapping input fields. The layers of the network provide continually higher‐level features until a classification can be made. After studying these networks, the question of their strengths and weaknesses in evaluating different types of datasets became a question. To that end, we tested convolutional neural networks on a variety of image datasets to compare its relative effectiveness. 68. Post OP Michael Andino, David Amick, Miller Fanning and Ryan Sprowles, Department of Computer Science There are very few, if any, open source social media applications. This led to the development of a new project known as Post OP. Post OP is an open source social media grouping application. The application was designed to allow the user to post statuses, images, and view live feeds for all of their selected social media sites. The application runs on AppJS and uses a SQLite Database, allowing the application to be multi‐platform. The process begins by saving user login credentials into the database as a way to persist login data. After the user has successfully logged in, the application retrieves the specific API and uses node.JS to post and receive requests from the respective social media site. The user has the ability to post to any and/or all social media sites at once through a single request. The results of this project have proven that open source social media integration is possible though very difficult. 69. Analysis of Terracing and Geomorphology of the Florida Escarpment Sarah Chahin and Leslie Sautter, Department of Geology and Environmental Geosciences Multibeam data were collected on the NOAA Ship Okeanos Explorer in 2011 and 2014 and post processed with CARIS HIPS to investigate the terracing features present in two study areas on APPENDIX F the Florida Escarpment. Study area 1 showed that the terracing features have gradual relief descending down the platform, but has a higher relief with near‐vertical drops (100‐400m) at the region of the area where terraces are present. A second study area showed similar features, although the relief in this location was more exaggerated and terracing started at a shallower depth with drops between 500 and 900 m. Backscatter data shows that in the locations where terracing is present, there is hard rock exposed, which is likely limestone. The forces affecting the geomorphology of the terraced features are turbidity currents, slope failure, ground water sapping, exfoliation and undercutting, and biogenic methane seeps. 70. Noise and Distortion in Mental Imagery Katie Lynam and Thomas Naselaris, Department of Biology and Program in Neuroscience, and the Medical University of South Carolina Department of Neuroscience fMRI studies show that visual perception and mental imagery are related, but not identical. In this study we show that it is possible to model and compare these processes using a simple visual task. We also attempt to determine the causes of error in mental imagery, which we believe is a result of noise and distortion. Subjects were shown an image on a computer and asked to remember it. Then they were shown probes and asked to count how many objects the probe covered in their mental image. Afterwards, a perception trial was conducted in which the probes and image were presented simultaneously. We found that there are differences between imagery and perception, mainly due to distortion. In addition, we created unique pictures representing each subject’s mental image and perception. Understanding these two processes can help explain errors in memory and improve treatments for mental disorders associated with mental imagery. 71. Method Development for Metabolomic Analysis by LC‐MS Elizabeth H. Blankenship, Wendy C. Cory and Jennifer L. Fox, Department of Chemistry and Biochemistry Specific metalation of metalloproteins is crucial for many biochemical functions and depends on well‐regulated metal transport and intracellular storage processes, including mechanisms that are less than fully understood. To investigate metabolic differences experienced by cells in response to varying metal ion availability, we developed methodology for metabolite extraction of Saccharomyces cerevisiae and analysis by ultra high‐performance liquid chromatography‐
mass spectrometry. These methods and the reproducibility of results from independent biological samples are presented here. 72. Fungal and bacterial composition of sea turtle nest sand at Ostional, Costa Rica Morgan Larimer, Kristina M. Hill‐Spanik, Vanessa Bezy and Craig J. Plante, Department of Biology APPENDIX F Olive ridley sea turtle hatching success is lower at mass nesting beaches than at solitary nesting beaches, presumably due to the high microbial activity that results from decomposing eggs crushed by overlapped nesting. Higher microbial activity at these sites increases temperature and decreases oxygen availability, potentially interfering with embryonic development. To discount specific pathogens or fungal invasions as possible causes of embryo mortality, a comparison of microbial species composition and diversity in areas of high and low survival was conducted using PCR‐DGGE. Preliminary results indicate no statistically significant difference between the fungal communities of the sample sites. The bacterial component of this research is ongoing. Additional analyses (i.e. band excision and DNA sequencing) are also planned. 73. Solvents, micelles, and random proteins: Are they different from computationally‐
designed Kemp eliminases? Enis Sanchez and Marcello Forconi, Department of Chemistry and Biochemistry De‐novo computationally‐designed enzymes can produce significant advancements in our ability to break down pollutants and cure diseases. The most promising enzymes are Kemp eliminases, which speed up the Kemp elimination reaction of 5‐nitrobenzisoxazole by 107‐fold using active site carboxylates as the general base. The factor of acceleration by the nonpolar solvent acetonitrile suggests that simply partitioning the substrate in this protein’s hydrophobic interior catalyzes the reaction. We used micelles and long‐chain carboxylates or phosphates to simulate this protein’s core. These simple model systems accelerated the reaction by 104‐fold. Linear‐free energy relationships suggest that the rate acceleration is due to the loose positioning of the substrate’s reactive groups rather than specific interactions between the substrate and the micelle or enzyme. The natural enzyme ketosteroid isomerase (KSI) possesses an active site capable of accommodating 5‐nitrobenzisoxazole and significantly accelerates Kemp elimination. We are currently using site‐directed mutagenesis to investigate this enzyme’s mechanism of action. Best of Biology 74. Roles for the complement anaphylatoxins C3a and C5a in regulating tumor immunity following radiation therapy Colleen Quaas1,5, Merry Andersen1,5, Andrea Whitfield2, Andrew Ellis3, Mario Fugal3, Kenneth Vanek3, Melissa Scheiber1,4,5 and Stephen Tomlinson1,3 1 Departments of Microbiology and Immunology, Medical University of South Carolina 2 Pediatrics, Division of Hematology/Oncology, MUSC APPENDIX F 3 Radiation Oncology, MUSC 4 Ralph H. Johnson Veterans Affairs Medical Center 5 College of Charleston Biology Department The complement system, comprised of over 30 soluble and cell surface proteins, is a vital component of the both the innate and adaptive immune systems. Complement activation leads to the generation of pro‐inflammatory anaphylatoxins, C3a and C5a. These pro‐inflammatory mediators have been shown to promote tumor growth. Using a mouse model of subcutaneous lymphoma (EL4), localized radiation therapy (RT) was shown to significantly reduce the tumor growth rate and increase survival in C3aR/C5aR knockout (KO) mice compared to wild‐type (WT) mice. Thirty‐seven days post initial RT, 66.7% of the KO that received RT had no detectable primary tumor. These six mice were re‐challenged with EL4 cells. After an additional 37 days, 5 of the 6 re‐challenged KO mice had no detectable primary tumor, suggesting an anti‐tumor memory response. Further studies are needed in order to confirm and determine the mechanism(s) responsible for this anti‐tumor immune response. 75. Using an Accumulation Contribution Fraction to Investigate Rainfall Joshua B. Teves and Michael L. Larsen, Department of Physics and Astronomy Using a dense optical rain gauge array near Charleston, SC, a novel measure of rain is used to categorize and analyze storm behavior. Using 14 non‐overlapping raindrop diameter ranges, the fraction of each size category's contribution to overall accumulation is determined. This "accumulation contribution fraction," fa, is calculated each minute over both a summer and winter storm. The diameter range with the largest fa, Ma, was determined for each minute. Assuming a Marshall‐Palmer distribution, the theoretical Ma was determined. Both theoretically and observationally, Ma's were determined. Strong agreement was found for the winter storm. In the summer storm, however, the theoretical Ma largely underestimated the observed Ma. 76. AquaTerra ArcGIS Plugin Nico Buescher, Christina Carmack, Caleb Whitaker, Zach Campbell and Thomas Mims, Department of Computer Science AquaTerra is a plug‐in that interfaces with the ArcGIS geographical mapping software provided by Esri. The AquaTerra toolbox prototype was developed by James M.L. Newhard, Norman Levine, and Angelina Phebus. The purpose of AquaTerra is to map out Terrestrial and Marine Communication Routes between two points on a map given a GeoDatabase. Our team has adapted and refactored the prototype with the intention of providing the modified AquaTerra python toolbox to the public as free and open source software that can be further modified. As a result the newly refactored AquaTerra is on GitHub ready to be collaborated on by an interested community. APPENDIX F 77. Scanning Electron Microscopy Analysis of El Guapo Chimney William G. Dennis‐King, M. Montgomery Taylor, Robert L. Nusbaum and Leslie R. Sautter, Department of Geology and Environmental Geosciences El Guapo is an active hydrothermal vent located along the Juan de Fuca ridge ~300 miles off the western coast of Oregon. A small (1‐m) inactive, parasite vent was collected from the base of El Guapo during the 2013 VISIONS’ 13 expedition led by University of Washington. Two cm‐sized flat segments were prepared for imaging and elemental analysis using a Tescan Vega3 Scanning Electron Microscopy (SEM) equipped with an energy dispersive (EDS) system. SEM/EDS analysis revealed textural and compositional variation between the two samples: one from the (vent) center and the other closer, but not at, the vent edge. The “central vent” sample consisted of colloform mafic glass with intergrowths of 20 micron Zn‐sulfide euhedra. The “closer to the edge” sample also exhibited colloform and amorphous masses of mafic glass along with disseminated 1‐micrometer Zn‐Fe sulfides. These observations may reflect temperature variation within this small vent when it was active. 78. Open Source: Diving into Firebug & CodeCombat Adam Sugarman, Jose Gonzalez, Will McCaskey and Scott Hallman, Computer Science Department Taking a step into the world of open source software can be overwhelming and hard to fathom for developers of any level. Four students dove into two different projects, Firebug and Code Combat. Firebug is a widely adopted extension to the popular Mozilla Firefox, allowing an extension to the built in web development tools to allow users to see any Javascript, HTML, Net requests, and CSS of any webpage live as they use it. Code Combat is a multiplayer strategy programming game aimed to teach users how to code through a interactive game played in any browser. While we experienced many failures in the Firebug project, we had much success contributing to Code Combat. Our poster will highlight our learning points from diving into the world of open source software and show our success in becoming contributors to projects used by millions. 79. Properties of the Coosawhatchie Clay of Jasper County South Carolina Katie Faust and Robert Nusbaum, Department of Geology and Environmental Geosciences Two specimens from stratigraphically adjacent beds of the Coosawhatchie Clay Member from the Hawthorn Formation were collected from Dawson’s Landing in Jasper County, South Carolina. The Hawthorn Formation is from the Miocene‐Plicocene Epoch and displays prominent outcrops in Florida, Georgia and South Carolina. Using an ASD spectroradiometer and observation of expansion qualities, it was determined that the clays were montmorillonite‐
rich. Further investigations using a scanning electron microscope for textural and chemical analysis supported this claim and provided possible explanations for why the two samples APPENDIX F behaved differently. The upper clay sample is rich with diatom fragments while the lower sample exhibits almost none. The results are consistent with a literary analysis that suggests a marine depositional environment for montmorillonite and the silica required for the abundance of diatoms. While no glass shards were observed as evidence of volcanic tephra, high silica and montmorillonite are consistent with a source of distal volcanism. 80. Hacking Brackets ‐ Contributing to an Open Source Web Development Text Editor Nora Grossman, Katherine Vaughan, Courtney Profera and Venessa Johansen‐Barrera, Department of Computer Science Brackets is an open source text editor meant to simplify and enhance the web development experience. Described as a “code editor for HTML, CSS, and Javascript that’s built in HTML, CSS, and Javascript”, Brackets supports a wide range of customization as well as live preview functionality for user interface development. Throughout the semester we have contributed to the project in a variety of ways, from fixing existing bugs and reporting new ones to extending the existing functionality to support syntax highlighting for additional programming languages and writing new visual themes. Although bug fixes are considered the de facto manner of contribution to an open source project, Brackets provided us with several different ways to support this vibrant development community, demonstrating that there are many different but equally valuable skill sets needed to create and maintain an open source project. 81. Phenotypic effects of multinutrient treatments on model plant system Arabidopsis thaliana Elsa A. Cousins, Clare Kohler, Rebecca J. Balazs and Courtney J. Murren, Department of Biology Root system architecture (RSA) and aboveground phenotypic components can be jointly and independently responsive to nutrient stress and can vary among populations. Ten worldwide natural accessions and five lines per six Iberian populations were grown in replicates under four nutrient treatments. We collected data on bolting date, rosette diameter and height. After harvest, additional aboveground data were collected and roots were scanned for RSA analyses. Phenotyping for this experiment is ongoing. Different nutrient levels result in distinct differences in RSA and aboveground traits. We detected genetic variation among populations for above and belowground traits. Low nitrogen treatments inhibited root growth across the lines and produced smaller rosette diameters, but some populations experienced milder effects. Studying natural variation and understanding stress tolerance in Arabidopsis provides insights into environmental responses that can be applied across plant species, especially those of agricultural significance. 82. Gene Expression Analysis of Candida glabrata Following Exposure to Complement‐Derived Antifungal Peptides APPENDIX F Mary Alice Cummings1,2, Silvia Vaena de Avalos2 and Caroline Westwater2,3 1 Department of Biology 2 Department of Oral Health Sciences, Medical University of South Carolina 3 Department of Microbiology and Immunology, MUSC Candida species are the most common fungal pathogen of humans. The goal of this study was to use a candidate approach to identify the intracellular events that are critical for complement peptide killing of Candida glabrata (Cg). We used the nanoString nCounter System, a technology that digitally measures target mRNAs, to identify processes that are altered in Cg cells treated with complement peptide. Cg was incubated in the presence or absence of sub‐lethal complement peptide and isolated RNA was mixed with a custom‐designed nanoString probe set. For each experiment, raw counts were adjusted for technical variability, and then normalized for total input RNA, using the geometric mean of robustly expressed genes. A number of Cg genes in the probe set were altered when the treated and untreated datasets were compared. Future studies will validate the gene expression data and evaluate mutants lacking the identified genes for susceptibility to complement peptides. 83. Applying Principles of Physics and Meteorology to Sea Fog and Rip Current Forecasting A. Clayton Caulder and B. Lee Lindner, Department of Physics and Astronomy , and Peter J. Mohlin, National Weather Service, Charleston Coastal hazard prediction can provide a unique challenge for weather forecasters because it involves a wide range of atmospheric and oceanographic processes and potential interactions between them. I explore potential summer research projects using National Weather Service data pertaining to sea fog and rip currents. I will document events of dense sea fog for correlation with various oceanographic and atmospheric data including air temperature, ocean temperature, wind speed, and temperature inversions. For rip current prediction, I will correlate the significant wave height and dominant period of offshore wind waves with the height of breaking waves on the coastline. 84. Salinity Tolerance in Southern Toads Emily Beam, Department of Biology Anthropomorphic activities are altering natural environments all over the world with direct implications for organisms and their choice of habitat. The use of road salts to de‐ice roads and agriculture have all introduced a higher level of salinity to surrounding areas than what would naturally be present. This presents a direct challenge, as it is known that amphibians have specific ranges of salinity tolerance and are poor osmoregulators. For the southern toad, Anaxyrus terrestris, a coastal organism, adults have been shown to have a range of tolerance for differing salinities while previous studies have provided evidence supporting a very limited tolerance of tadpoles. Obviously, salinity tolerance varies between life stages. This research APPENDIX F seeks to understand how physiological and behavioral responses to salinity vary from tadpole, to metamorph, to adult life stages. This would work to better assist conservation as it is important to denote which specific life stages are most imperiled. 85. Body Condition of African Elephants Emily Beam, Department of Biology Body condition of individuals relates directly to foraging success and health, and therefore is an important tool for conservation. In this study, a body condition mixed model was used to assess free‐ranging African elephant health and contributing factors in the Tarangire‐Manyara Ecosystem in three protected areas. Seasonality was the largest factor—the average body condition score in the dry season was more poor than scores in the wet season. Another contributing factor was location. The highest body condition scores were found in Lake Manyara National Park, then Manyara Ranch, then Serengeti National Park, and lastly, Tarangire National Park. In the United States, captive elephants were also assessed based on body condition. Though the sample size was small, it was found that out of three locations, a sanctuary environment had higher mean body condition scores than zoo environments. 86. Geomorphology of Lighthouse and Turneffe Fore‐Reefs: Exploration using Backscatter Kristin Hughes and Leslie Sautter, Department of Geology and Environmental Sciences Deep sea corals are known to form in areas with a topographically enhanced bottom composed of a hard substrate on which attachment is possible. Bathymetric data were acquired for areas of interest in search of deep sea corals from the deep‐water eastern flank, or fore‐reef of Lighthouse Reef Atoll and the southern fore‐reef of Turneffe Reef: 2 of 3 atolls that lie on Belize’s continental margin. With depths reaching 4,000 meters, the atolls lie on submarine ridges just west of the Yucatan Basin. The deep waters of these escarpments have potential for being suitable habitats for deep‐sea corals to thrive. Through this research, it is our hope to benefit future ROV exploration by mapping areas of interest in search of deep‐sea coral habitats. Furthering research of these atolls is crucial for understanding the delicate, threatened ecosystems of deep‐sea corals. 87. Spit Growth and Decay at Pawleys Inlet, South Carolina from 1994 to 2014 Dante Curcio, Mason Atkinson and Leslie Sautter, Department of Geology and Environmental Geosciences Pawleys Inlet is located on the South Carolina coastline between Pawleys Island and Debidue Island. Having an ebb‐tidal delta along with a strong northeast‐southwest longshore current, this inlet migrates rapidly, primarily due to spit accretion on Pawleys Island. The spit can be breached by storm waves, relocating the inlet and causing accretion on Debidue Island’s north end. Google Earth historical images from 9 years between 1994 and 2014 were used to better APPENDIX F understand how sediment fluctuates between the spit, ebb delta shoals, and the north end of Debidue Island. Following a breaching event between 1995 and 1999, Pawleys’ spit area decreased by 14,000 m2, and continued to erode between 1999 and 2005, resulting in a total decrease of 39,365 m2. Much of the sand migrated to Debidue Island during that time period, resulting in accretion of 22,000 m2. 88. Geomorphology of Two Puerto Rico Protected Habitats Evalynn Barbare and Leslie Sautter, Department of Geology and Environmental Geosciences Seafloor geomorphology was examined for two distinct protected tropical habitats, located off the northeast coast of Puerto Rico within the Northeastern Grand Reserve Ecological Corridor, and off the southern coast of the nearby Isla De Vieques. These continental shelf and slope areas were surveyed in March 2013 covering depths between 25 and 1150 m. Approximately 866 species of coral reef fauna inhabit these protected areas, and concern has been raised as to their stability to withstand complications. Features of the Reserve and Vieques margins were characterized and compared, and include submarine canyons that plunge approximately 900 m, and fore‐reef edges of coral reef habitat on the continental shelf. These bathymetric 2D and 3D surfaces will be useful as baseline surveys of the critical protected areas to estimate future continental shelf and slope changes. 89. Inlet Orientation Associated with Bar Bypassing and Deposition in a Barrier Inlet System: North Island, South Carolina Nicholas C. Damm, Kristopher J. Enfinger, William L. Hefner and Leslie Sautter, Department of Geology and Environmental Geosciences Google Earth Pro satellite imagery from 1994 to 2013 was used to examine the relationship between inlet migration and general morphology of the downdrift barrier island at North Inlet, South Carolina. Using a reference line to divide the inlet into throat and tail sections, the orientation of the deep water channel was documented for each study year. The downdrift island’s north end was divided into three equal quadrants to examine accretion and erosion trends. Orientation measurements display a southern trend from 1994 to 2010 shifting 16.91o. As the inlet moved southward, the Central quadrant showed an increased deposition of 31,722 m2, whereas the North quadrant eroded. The South quadrant remained relatively stable until 2010 when a slight shift in tail orientation resulted in a bar bypassing event and subsequent shoal attachment. Therefore, the inlet orientation drives the downdrift barrier island geomorphology and plays a critical role in bar bypassing processes. 90. Ebb‐Delta Breaching and Swash Bar Migration at Breach Inlet, South Carolina, From 2001‐
2014 Cameron Troilo, Sonja Tyson, Sue Morrison and Leslie Sautter, Department of Geology and Environmental Geosciences APPENDIX F In South Carolina, mixed tidal and wave energy environments create an abundance of tidal inlets. Breach Inlet, located between Isle of Palms and Sullivan’s Island, influences the geomorphology of the flanking barrier islands because of channel direction and wave refraction, causing periodic shoal bypassing events due to ebb‐tidal delta breaching events. Google Earth images from 2001 to 2014 were used to quantify measurements and descriptive statistics. Ebb‐delta breaching and shoal migration affect erosion and accretion rates downdrift and updrift. The average total swash bar volume is 447,610 m3 per year, with increased volumes occurring before breaching with shoal bypassing events in 2005 and 2010. Repeated bypassing events cause tombolo effects on Sullivan’s Island while Isle of Palms experiences accretion or erosion based on channel position. The high rate of swash bar migration causes erosion and accretion on short timescales, which inhibits full development of dune complexes on both islands. 91. Morphodynamics of Captain Sam's Inlet, SC from 1989 to 2014 Cara Lauria, Shelby Bowden and Leslie Sautter, Department of Geology and Environmental Geosciences Captain Sam’s Inlet is a migrating ebb tidal inlet located along the central mesotidal South Carolina coast between Kiawah and Seabrook Islands. Evidence for the main inlet channel migration and pivoting is shown by accretion and erosion patterns of adjacent barrier islands. Migration of the channel southwestward was consistent throughout the study years 1989 to 2014, except for an engineered breaching in 1996. Kiawah Spit showed an average increase in area at a rate of 3.36 km2/year prior to breaching and 18.49 km2/year following the breaching. Accompanying the spit’s extension is a southwestern pivot of the main inlet channel at a rate of 1.91 m/year prior to breaching and 1.05 m/year following the breaching. Quantitative and qualitative measurements collected in this study reveal the morphology of a dynamic inlet downdrift of a recurved spit. 92. Synthesis and Computational Analysis of a Novel, Bis‐Indenyl 'Batwing' Ligand Carson W. Reed, Travis P. Varner and Richard A. Himes, Department of Chemistry and Biochemistry During the synthesis and development of new carbon‐carbon bonds in molecules, it is vital at times to utilize a catalyst that will exhibit some control over the reaction. The chemistry of indene derivatives bound to transition metals has proven fruitful in this area. More specifically, indenyl ansa‐metallocene complexes of titanium and zirconium have characteristic and unique reactivities, especially for controlling the tacticity of polymer synthesis. Slight modifications of indenyl ligands have been shown to have potentially drastic effects on polymerization reactivity. Therefore, we have designed and synthesized a novel, polycyclic, bis‐indenyl 'batwing' ligand through two separate synthetic routes. The steric and electronic consequences of this ligand will be explored and discussed through both experimental and DFT computational methods. APPENDIX F 93. Geomorphologic Analysis of the Eastern Slope of Glover’s Reef: a Coral Atoll on the Continental Margin of Belize Kori Ktona and Leslie Sautter, Department of Geology and Environmental Geosciences Multibeam sonar data of the eastern slope of Glover’s Reef atoll were collected by NOAA marine biologist Dr. Peter Etnoyer. Glover’s Reef is an atoll within the Mesoamerican Reef, located approximately 45 km east of the Belize mainland. This study of the geomorphology of the seafloor could potentially lead to a better understanding of the entire biological system of deep sea coral habitat. Sonar data were post‐processed to generate bathymetric 2D and 3D images, and backscatter was used to determine the character of the seafloor, including probable locations for deep‐sea corals. Results show various interesting features including canyons and depths over 2,800 meters below sea level. The seafloor characteristics that were defined using backscatter allowed for identification of potential hard‐bottom locations of deep‐
sea coral habitats. Detecting these environments is crucial for the continuation NOAA’s work studying the deep‐sea corals of this atoll. 94. Toward Developing an Expert System for Classifying Gamma‐Ray Burst Pulses Maly Taylor, Thomas Cannon, Stephen Lesage, Eric Hofesmann, Ethan Redel, Samantha Word, Jacob Epps and Jon Hakkila, Department of Physics and Astronomy Gamma‐ray bursts consist of pulses that range from the simple to the complex. We can improve upon the empirical Norris pulse model by fitting the pulse residuals with the Hakkila fitting function. We apply this approach to the gamma‐ray data collected by the Burst And Transient Source Experiment (BATSE). Via an expert system we determine which entries will be added to our BATSE gamma‐ray burst pulse catalog. Through discussion and comparison, we identify adequate pulses for catalog inclusion; this is difficult given the low signal‐to‐noise of BATSE data coupled with an apparently large range of pulse characteristics. 95. The Fitting Process for Gamma Ray Burst Pulses Stephen Lesage, Thomas Cannon, Maly Taylor, Eric Hofesmann, Jacob Epps, Samantha Word and Ethan Redel, Department of Physics and Astronomy We present a process for modeling and fitting gamma‐ray burst pulses. The bursts in this sample were observed by the Burst and Transient Source Experiment (BATSE) on NASA’s Compton Gamma‐Ray Observatory. The Norris fitting function is the four‐parameter model represented by two merged exponential functions. The model easily reproduces multichannel light curves of isolated pulses. However, when fitting many pulses, operator intervention is often required. In many cases the operator must adjust the parameter settings and determine if the output the program has created a good fit, bad fit, or if the pulse structure is simply too uncertain to be fit by the model. APPENDIX F 96. Proposed Mission to Europa Stephen Lesage, Thomas Cannon, Ethan Schneider and Madysen Cheek, Department of Physics and Astronomy Jupiter's satellite Europa has a liquid water ocean under its icy exterior that could harbor life. We have developed, in conjunction with UAH engineering students, a mission to Europa with the purpose of determining whether or not Europa's structure is conducive to the development of life. Upon arrival at Europa our mission will establish a polar orbit and deploy between nine and eighteen "temporary probes" as well as one large lander. The network of probes will gather seismic data for 30 days. The lander will study a previously discovered large plume of liquid water near the South Pole. The orbiter will map the surface at multiple wavelengths. Our observations will tell us about Europa's surface, interior, the chemicals on both the surface and interior, how these chemicals interact with one another, and the probability of life being able to develop and grow in a habitat such as this. 97. Analysis of Raindrop Time Series via a Size‐Dependent Pair Correlation Function Robert Lemasters and Michael L. Larsen, Department of Physics and Astronomy There is empirical evidence that large raindrop arrival times are not perfectly random. Additionally, it has been observed that a substantial portion of smaller drops tend to be falling at superterminal velocities. The exact mechanism for these phenomena are not clear and it is uncertain whether they are related. In an effort to identify any correlation, the authors use a generalized notion of the temporal cross‐correlation function for use with discrete data. This tool, which will be called the "size dependent pair correlation function" (SDPCF), is applied to data provided by a 2‐dimensional video disdrometer. 98. Mycobacteriophage Pipsqueaks: The Complete Genome Annotation of a New Cluster N Phage Heba Abdin, Victoria Edmund, Brianna Harmon, J'Neice Payne, Brandi Bell, Samaria Boyd, Samantha Bridges, Maya Dilligard, Taylor Gibson, TaMia Morris, Cherie Pitts, James Solomon and Christopher Korey, Department of Biology HHMI SEA‐PHAGES is a yearlong research‐based course that allows undergraduate students to collaborate with faculty mentors and discover new scientific information. This program is run with first‐year students in collaboration between the First Year Experience and the South Carolina Alliance for Minority Participation (SCAMP). In the fall semester, students isolated novel bacteriophage viruses from soil samples using a variety of laboratory tools and techniques. The bacteriophage Pipsqueaks was selected from the six phage identified in the first semester to be sequenced at the University of Pittsburgh. In the spring semester, students in the First Year Experience Research Course explored basic annotation and bioinformatics. Pipsqueaks’ genome sequence was annotated from the 5’ to 3’ end using the DNA Master APPENDIX F Genome Annotation Software. We identified the open reading frames based on the predicted coding potential using the annotation algorithm programs Glimmer and Gene Mark. Here we present the initial data from the annotation of this new cluster N phage. 99. Vagus Nerve Stimulation as a Treatment for Parkinson's Disease Donna Davis1, Ariana Farrand2, Rebecca Gregory3, Kristi Helke3, Seth Hays4, Vanessa Hinson5 and Heather Boger6 1 Department of Exercise Science and Program in Neuroscience, College of Charleston 2 Department of Neuroscience and Center on Aging, MUSC 3 Department of Comparative Medicine, MUSC 4 Department of Bioengineering, University of Texas at Dallas 5 Department of Neurology, MUSC 6 Department of Neuroscience and Center on Aging, MUSC Vagus nerve stimulation (VNS), currently FDA approved for the treatment of drug‐resistant depression and epilepsy, has been shown to induce various electrochemical changes in brainstem nuclei and their projections, including the increase of brain derived neurotrophic factor (BDNF) in locus coeruleus (LC) target regions. In Parkinson’s disease (PD), studies have shown that the LC noradrenergic (NE) neurons degenerate prior to the dopaminergic (DA) neurons in the substantia nigra (SN). Therefore, we hypothesize that noradrenergic degeneration regulates growth factor expression in a rat model of PD. To evaluate this hypothesis, a neurotoxic double‐lesion model was used to mimic the effects of PD. Following two weeks of VNS, stimulated rats showed greater locomotor activity, as well as increased BDNF levels in the frontal cortex and striatum and an increase in dorsal striatum density compared to the non‐stimulated rats. Taken together, these data indicate a potential beneficial use of VNS in the treatment of Parkinson's disease. 100. The Discovery and Isolation of Six New Mycobacteriophage from the Historic Soil in Charleston Heba Abdin, Victoria Edmund, Brianna Harmon, J'Neice Payne, Brandi Bell, Samaria Boyd, Samantha Bridges, Maya Dilligard, Taylor Gibson, TaMia Morris, Cherie Pitts, James Solomon and Christopher Korey, Department of Biology HHMI SEA‐PHAGES is a yearlong research‐based course that allows undergraduate students to collaborate with faculty mentors and and participate in the research process. This program is run with first‐students in collaboration between the First Year Experience and the South Carolina Alliance for Minority Participation (SCAMP). In their fall semester, students used a variety of laboratory techniques to isolate novel bacteriophages that infect Mycobacterium smegmatis from soil samples. Using sterile techniques and plaque assays, we were able to isolate 6 new phages. We created a high titer lysate that contained a high amount of phage to isolate genomic DNA to be sequenced. At the conclusion of the fall semester, the phage Pipsqueaks was selected to be sequenced at the University of Pittsburg. These new phages will APPENDIX F help in the broader understanding of phage evolution and will contribute to a library of phage being developed as potential therapeutics against M. tuberculosis. 101. Influence of Neck Width on the Hemodynamics of Intracranial Cerebral Aneurysms Allison Conger and Jason Howell, Department of Mathematics Recent advances in medical imaging technologies have enabled the study of the hemodynamics of arterial aneurysms through computational fluid dynamics (CFD) simulations. Researchers in medicine and biomedical engineering have discovered that several measures of the blood flow near and inside aneurysms may lead to enlargement and/or rupture of the aneurysm. These measures include the fluid wall shear stress (WSS) along the interior aneurysm wall, as well as the Oscillatory Shear Index (OSI). This project seeks to investigate the effect that the width of the entry point of an intracranial aneurysm has on the WSS and OSI, and therefore its enlargement and rupture. 102. The Role, Expression and Connectivity of Neuronal Nitric Oxide Synthase: Implications for Cocaine Addiction Melissa Lorang, Peter Kalivas and Alexander Smith, College of Charleston Department of Biology and Program in Neuroscience and the Medical University of South Carolina Department of Neuroscience Chronic cocaine use induces plasticity within a projection from the prefrontal cortex to the nucleus accumbens core (NAc). The extracellular matrix modifies plasticity through matrix metalloproteinases (MMPs). Nitric oxide (NO) synthesized by neuronal nitric oxide synthase (nNOS) activates MMPs. Cocaine use amplifies nNOS production causing greater MMP activity. nNOS role in MMP activation was determined by site‐specifically inhibiting nNOS prior to cue‐
induced reinstatement, then analyzing MMP activity. This study hypothesized and confirmed nNOS inhibition attenuates reinstatement of cocaine seeking, as well as the associated increase in MMP activity. The abundance and colocalization of nNOS interneurons were compared to parvalbumin and choline acetyltransferase interneurons, which demonstrated nNOS interneurons are a unique cell type within the NAc and do not colocalize with either GABAergic interneuron. Furthermore, the prelimbic cortex, dorsal raphe nucleus, and ventral tegmental area exhibit direct monosynaptic connections to nNOS cells. 103. Geomorphology of the Southwest Coast of County Cork, Ireland: A Look into the Rocks, Folds, and Glacial Scours Shelby Bowden, Rachel Wireman, Erin Beutel and Leslie Sautter Department of Geology and Environmental Geosciences Bathymetric data were collected off the southwest coast of County Cork and computer generated 2D and 3D bathymetric surfaces were used to examine some of the lithologic APPENDIX F formations. Several large rock outcrops occur showing a vertical rise of nearly 20 m. These outcrops are oriented in a northeast‐southwest direction, and exhibit significant bed folding and tilting, regional folding, and cross joints. The folds studied are plunging chevron folds. These folds have a northeast‐southwest fold axis orthogonal to the cross joints and are older relative to the jointing systems. The NE‐SW joints are older than the NW‐SE joints due to their correlation with drainage and erosion patterns. Regional folding is the youngest feature due to its superposition on the chevron folding and jointing systems. The interaction of cross jointing and folding is consistent with the geologic history of the area, and creates a unique bathymetry worthy of further study. 104. Optical Properties of Zinc Oxide Doped with Argon and Oxygen Leisha Lopez1, Narayanan Kuthirummal1, Ramakrishna Podila2 and Apparao Rao2 1 Department of Physics and Astronomy, College of Charleston 2 Department of Physics and Astronomy, Clemson University We have investigated zinc oxide (ZnO) semiconducting nanoparticles (~80 nm) doped with Argon (Ar) and oxygen (O2) using photoacoustic spectroscopy (PAS). Although the bandgaps did not show notable changes upon increasing the concentration of impurities, the steepness and Urbach energy parameters revealed significant changes. The Urbach energy parameter increased from 0.1478 eV to 0.1870 eV for ZnO doped with Ar (0.1478 eV to 0.1865 eV for oxygen doped samples) revealing increased density of defect states and hence a wider conduction band tail. Upon further increasing the impurity concentration, the Urbach energy shows saturation behavior for both Ar and O2 doped ZnO samples. Best of the Best, and Best of Geology and Environmental Geosciences 105. Prediction of Catastrophic Eruptions of Volcán de Colima, Mexico Via Analysis of Long Term Trends in Lava Geochemistry Haley Cabaniss1, John Chadwick1, Erin Beutel1 and Nick Varley2 1 Department of Geology and Environmental Geosciences 2 Universidad de Colima, Facultad de Ciencias Volcán de Colima, Mexico is one of the most active volcanoes in the world, erupting dozens of times in the past century. It is therefore an excellent laboratory for understanding temporal APPENDIX F patterns of eruption activity and investigating how eruption magnitudes may relate to the varying chemistry of its erupted lavas over time. The chemistry (including volatiles) of volcanic systems are the most important drivers of volcanic eruptions; understanding their behavior before, during, and after an eruption may result in a better mechanism for predicting the particularly powerful and deadly eruptions that occur about once every century in Colima. X‐ray fluorescence spectrometry and Electron microprobe analyses of melt inclusions within plagioclase phenocrysts was undertaken for rock samples from 1998‐1999, 2004, and 2013‐
2014 andesitic lava flows; these data will become part of a larger project to observe the evolution of sulfur concentrations over one complete cycle of volcanism of Volcán de Colima. 106. Open‐Source Contributions to Moodle Don Cole, Jason Curry and Oddom Vong, Department of Computer Science Moodle is a widely used, free and open source software (FOSS) learning platform that is, in many ways, similar to Oaks. It allows educators to create secure, personalized learning environments for their students. Because it is open source, it is highly flexible and allows individual modules and components to be added or removed by users. Its flexibility also allows it to organize online classes as well as blended learning. Moodle is written in PHP and backed by a MySQL database. Our team made a number of contributions to the project, with examples including fixing issues in SQL queries and data retrieval for HTML table generation. 107. Data Reduction Techniques for Circumstellar Disk Imaging with the Hubble DICE Survey Benjamin Wilson, Zach Griggs, Clay Gardner and Joe Carson, Department of Physics and Astronomy We present a status report on the effort to develop computational tools to improve the effective sensitivity of Hubble Space Telescope (HST) imaging observations of circumstellar disks around nearby stars. Specifically, we are implementing an algorithm that enables one to combine tens or hundreds of digital images in a manner that strips away the overwhelming light from the parent star, while leaving intact the faint light from the surrounding disk. Our implemented image processing components are described in the sections of RAM, Shizzle, RSS, LOCI, Outlier Pixel Rejection, and Boxcar Smoothing. The ultimate goal is to reveal disk substructures which can indicate the presence of planetary formation and evolution. 108. Human Genomic Variation in Functionally Polymorphic Genes Andrea Nillas and Andrew Shedlock, Department of Biology This project aimed to identify differential expression of functionally polymorphic genes between human populations. Six loci (APOH, AVPR1a, CYP2C9, HERC2, MC1R and VDR) were APPENDIX F selected and buccal DNA was extracted from human subjects of differing ethnic backgrounds for analysis to determine if ancestral conditions affected modern evolution of these genes. Appropriate primers were designed and PCR conditions were optimized to amplify target DNA segments. Successful amplifications were identified by gel electrophoresis, cleaned and directly sequenced. Sequences were edited with FinchTV, aligned in MEGA and compared to the NCBI reference database with BLAST to detect polymorphism. When referencing the Human HapMap project, loci HERC2 and APOH exhibited diagnostic mutations suggesting possible differential selection. Based on these preliminary results we expect a more extensive haplotype survey of Indo‐Pacific vs. European subpopulations could elucidate how shifts in ancient demographics and culture may have impacted the phenotypic expression of these genes 109. Hypermutation of the Immunoglobulin Heavy Chain Genes in Zebrafish Kaitlyn Ballotti, Joshua Shaffer and Anastasia Zimmerman, Department of Biology The Zebrafish, Danio rerio, has become a popular model for comparative immunology and biomedical research. In humans, mutations at antibody (Ig) loci are critical for effective immune responses. Knowledge of DNA motifs that are targeted for mutation can be used for understanding antibody responses to various infections, B‐cell cancers, and autoimmune diseases. It is our goal to determine which DNA bases are prone to mutation in Zebrafish immunoglobulin heavy chain genes (IgH). By aligning IgH mRNA transcripts to genomic sequences, biases in DNA mutations at specific base sequences, or AID hotspot motifs, can be discerned. We have obtained over 90 cDNA clones. In aligning these clones to the Zebrafish genome, we have found certain motifs that display high rates of mutation. Understanding how mutations generate antibody diversity is important to establish D. rerio as an immunological model and provide insight for creating novel vaccines and immunotherapies. 110. Solar Photodegradation of Pharmaceuticals in the Aquatic Environment Taylor Domenick, Lisa Kasprzok and Wendy Cory, Department of Chemistry and Biochemistry Pharmaceuticals and their degradation products have been observed in the environment, where they pose potentially negative effects to humans and other organisms. Degradation products may be more environmentally persistent and more toxic than their parent compounds. To investigate the environmental fate of commonly prescribed antidepressants, we measured their solar photodegradation rate in samples simulating the natural aquatic environment. Aqueous drug samples were prepared in 5 mM phosphate buffer (pH=7.0), with and without the organic degradation product humic acid (HA). These samples were photoexposed in a solar simulator and aliquots were taken at relevant time points and analyzed using HPLC and LC‐ESI‐MS. The half‐lives were calculated using pseudo‐first order rate laws. We observed that for most concentrations HA acted as a photosensitizer, speeding up the photodegradation of the compounds. Photodegradation products of sertraline and fluoxetine were detected using LC‐ESI‐MS and structures proposed. APPENDIX F 111. Effect of N‐Acetylcysteine on Appetitive Processes and Preventing Relapse in Adult Smokers Megan White, Neringa Stankeviciute, Patrick A. McConnell and Brett Froeliger Department of Psychology, Program of Neurosciences, College of Charleston Department of Neuroscience, Medical University of South Carolina Hollings Cancer Center, MUSC Department of Psychiatry, MUSC Nicotine interferes with glutamate transmission between the prefrontal cortex and nucleus accumbens, an integral pathway to reinstating drug seeking behaviors and mediating top‐down cognitive control and is interrupted by addiction. In animal models, N‐acetylcysteine (NAC) has restored corticostriatal glutamatergic transmission levels and decreased drug‐seeking behaviors. The effects of NAC have yet to be demonstrated in humans addicted to nicotine. The present study examined the influence of NAC on withdrawal symptoms and self‐administration in adult nicotine‐dependent smokers. Participants were randomized to receive either NAC or matched placebo (PBO) over the course of 3 ½ days of monetary‐incentivized smoking abstinence. Participants came to the lab on each abstinence day so that their smoking could be biochemically monitored. Data revealed that compared to the PBO group, smokers in the NAC group significantly reduced smoking, reported less craving and higher positive affect, suggesting that NAC may help prevent relapse via appetitive process restructuring. 112. Cu‐Catalyzed Addition of Alkynyl Trifluoroborate Salts to Imines Justin Dorris, Department of Chemistry and Biochemistry Cu‐catalyzed additions of potassium alkynylboron trifluoride (BF3K) salts to imines are described. The propargylamine products are useful building blocks in organic synthesis. This addition reaction has also proven to be amenable to the synthesis of racemic unnatural amino acids bearing an alkyne moiety. Unnatural amino acids bearing these alkyne moieties could be useful for inclusion in peptides. 113. Varying Forms of Gamma‐Ray Bursts Eric Hofesmann, Jon Hakkila, Thomas Cannon, Stephen Lesage, Corinne Maly Taylor, Jacob Epps, Ethan Redel and Samantha Word, Department of Physics and Astronomy In the process of constructing a gamma‐ray burst pulse catalog, we have found that there are some gamma‐ray burst light curves that defy current modeling procedures. Many of the bursts that are unfittable share common characteristics. We have begun to group these bursts together based on their observed features. We have named three easily identifiable groups as "Doubles," "Triples," and "Crowns." Doubles and Triples consist of two or three overlapping emission episodes to the extent that the pulse‐fitting program is able to differentiate between APPENDIX F them. The Crowns are composed of single emission episodes having very jagged maxima composed of many peaks. However, some gamma ray bursts have light curves that are intermediate between these groupings: these apparently indicate a gradual shift in complexity that may help us understand these varying types of bursts. 114. Predicting March Madness Using Probabilities Liana Valentino, Department of Mathematics Numerous predictive models exist that are used to predict a bracket for the NCAA March Madness tournament. Basketball analysts have different opinions regarding which statistics are important to use and the weight of importance associated with each statistic; this discrepancy provides the option to use a variety of different models. Instead of focusing on one model, the current research discusses using several methods with different weights and using the probabilities of teams advancing to create a bracket. This allows a bracket to be created from a combination of many models, instead of using a sole method. 115. Beating the Odds ‐ Massey March Madness John Sussingham, Department of Mathematics What is it about March Madness that draws the attention of millions each year? Is it the the aimless stab at creating the perfect bracket? Or perhaps the upsets and unpredictability of it all? The following analysis will reveal which years were predictable vs. unpredictable and how to use this information to form a bracket for this year. One will also learn how to modify the Massey Method of Ranking by implementing various weightings and inducements. Additionally, we will examine each round of the March Madness Tournament as its own separate entity. This will allow us to manipulate our bracket into six sections and apply those different methods to assess and predict each round. In a final analysis, a comparison shall be made between the predicted spreads of our methods to those of Vegas. 116. Synthetic modeling and spectral analysis to determine the surface properties of stars Annie Steele and James Neff, Department of Physics and Astronomy While the surface of the sun is easily resolved, distant stars can only appear as points of light, therefore determining the total starspot area must be accomplished using a circulatory approach. Titanium oxide (TiO) presents itself as a capable indicator of starspots because it maintains its structure in cooler regions in the stellar surface. Synthetic spectra were created using the SPECTRUM program and MARCS models. The average flux value was taken both before and after the band heads at 7055Հ and 8860Հ. The flux ratios taken from hot stars are indicative of active stellar surface regions while cool star ratios are used to indicate starspot regions. These TiO ratios are used to estimate starspot temperature and total starspot coverage by both observed and synthetic spectra. APPENDIX F 117. The Photodegradation of Diphenhydramine in Simulated Natural Water Aliya Dumas and Wendy Cory, Department of Chemistry and Biochemistry Pharmaceuticals can re‐enter the sewerage system either by human execrations or improper disposal, leading to detection of low concentrations of pharmaceuticals in the water supply. Active compounds in the water can be exposed to UV light which can facilitate degradation. Thus studies to understand the effects of these compounds, and their degradants on human, aquatic life, and the environment are warranted. Diphenhydramine, the active ingredient in Benadryl is a commonly used drug. We were able to determine the half –lives of 500 ppb diphenhydramine solutions with varying amounts of humic acid using High Performance Liquid Chromatography. Possible degradation products were determined using Ultra High Performance Liquid Chromatography‐Electron Spray Ionization‐Mass Spectroscopy. Structures of these degradation products will be confirmed in the future with MS/MS. 118. Characterizing a New Method of Harvesting Energy from the Natural Environment and Exploring the Physics of the Triboelectric Effect Ryan Michael Sullivan and Alem Teklu, Department of Physics and Astronomy A prototype DC triboelectric generator (DC‐TEG) is presently undergoing a proof of concept investigation in order to determine its feasibility as a new system for harvesting energy from the natural environment. The DC‐TEG converts rotational motion into electrical energy through the utilization of the triboelectric effect between Nylon fabric and Polytetrafluoroethylene (PTFE) tape. Preliminary results have demonstrated that DC current is generated with the magnitude dependent on angular frequency, surface‐contact area, and properties of the triboelectric materials. Measurements using angular frequencies between 0 and 10 revolutions per second (RPS) have yielded DC currents and voltages with orders of magnitude of 10^(‐9) and 10^(‐3), respectively. However, recent modifications have advanced the performance of the open‐circuit voltage by a factor of roughly 2 for angular frequencies between 10 and 15 RPS. Future work will be to explore different circuits with the DC‐TEG and to model its behavior conceptually and mathematically. 119. Exploring the Bathymetry, Geomorphology, and Seafloor Substrate off the Western Flank Turneffe Atoll, Belize Rebekah Gossett and Leslie Sautter, Department of Geology and Environmental Geosciences Turneffe Reef is a carbonate platform and atoll within the Belize MesoAmerican Reef. The reef flank extends to depths of over 1000 meters and may provide habitat for critical deep coral species. Using multibeam sonar data collected by NOAA scientist Peter Etnoyer aboard the Ocean Exploration Trust’s E/V "Nautilus", variations in bathymetry, seafloor substrate, and geomorphology on the northwest flank of Turneffe Reef were examined in order to hypothesize the identity of rounded structures found along the reef margin at depths ranging from 500 to APPENDIX F 900 m. CARIS HIPS and SIPS 8.1 was used for post‐processing bathymetry and backscatter data, to determine variations in seafloor hardness and identify potential deep coral sites. Characteristics of the geologic structures surrounding Turneffe Reef provide insight as to how deep coral is supported, and to identify sites to investigate on future ROV missions. 120. Investigation of microbial carbonates of the western shoreline of Storr’s Lake, San Salvador, Bahamas Kyle W. Bostick, Mitchell Colgan and James Carew, Department of Geology and Environmental Geosciences Extremophilic life continues to push the environmental bounds of what we consider habitable for life. Microbialites are organosedimentary deposits formed in the presence of microbial biofilms/mats and benthic metazoan communities; these biofilms often thrive in extreme environments where microbial‐grazers are absent. Microbialites form as the result of 1) trapping/binding sediment with extracellular polymeric substances and 2) the process of organomineralization. This project has focused upon modern microbialites present in hypersaline Storr’s Lake located in San Salvador, Bahamas. Microscopy investigation has highlighted meso‐ and microscale petrographic diversity of both Dichothrix and Scytonema microbialites from the western shoreline of Storr’s Lake. We have hypothesized that variations in morphology are dependent upon the dominant genus of cyanobacteria, depth of formation, and geographic location. Through observation and literature review, we have concluded that Dichothrix microbialites form through trapping and cementation of surrounding sediments while Scytonema microbialites depend on organomineralization of High‐Mg calcite. 121. Quantifying the Difference Between Imagery and Perception in the Human Brain Andrew O’Laughlin and Thomas Naselaris Naselaris, College of Charleston Department of Biology and Program in Neuroscience, and Medical University of South Carolina, Department of Neurosciences When imagining a scene, the images in your head do not precisely reflect the state of objects in the actual scene. Some parts of the brain are not as engaged when forming a mental image, leading to discrepancies from perceiving an image. One long‐standing question in neuroscience is what parts of the brain are involved in forming a mental image. To investigate, we quantitatively determine the difference in brain activity when imagining something versus physically perceiving that thing with your eyes. An experiment with two separate fMRI scans quantifies the difference between imagery and perception. In the first scan, subjects are shown five different works of art and in a second scan they are told to imagine those same works. Analysis on the fMRI data reveals which parts of the brain are active when visually perceiving the art versus what parts are active when imagining the art. 122. Effects of Beach Renourishment on Benthic Microalgal Communities and Biological Sediment Armoring APPENDIX F Aubrey Butcher, Kristina M. Hill‐Spanik and Craig Plante, Department of Biology One method of preserving beaches against the effects of erosion and sea level rise is beach renourishment. The town of Folly Beach completed a beach renourishment project from January 2014 to June 2014, which involved pipelining sediment from an offshore borrow site directly onto the beach face. Unlike many other studies that look at the effects of beach renourishment on macro‐fauna, this study aims to monitor the effects of beach renourishment on benthic microalgae (BMA) microscopic, photosynthetic organisms present in coastal sediments. The main objectives of this study were to determine how BMA biomass, community composition, sediment granulometry, and sediment erodibility were altered by renourishment. Results to date indicate that biomass and composition of benthic microalgal communities were altered by renourishment, biomass recovery occurring between 88‐164 days. Sediment erodibility was initially higher in renourished areas, with recovery occurring in 2‐4 months, depending on beach height. 123. Diabetes, Health Literacy and Mobile Technologies Katie Kirchoff, Department of Computer Science As health research continues to develop new technologies for patients to better care for health concerns from home, a serious challenge for healthcare professionals is the health literacy of patients. Health literacy is defined by The Patient Protection and Affordable Care Act of 2010, Title V, as the degree to which an individual has the capacity to obtain, communicate, process, and understand basic health information and services to make appropriate health decisions. Through my experience as a research assistant on a project studying health literacy in African American patients within eight counties of South Carolina at MUSC, I have learned a significant amount about diabetes, health literacy and health care education. From my work on the grant and additional research, I have developed the framework for a new type of mobile application that takes into account health literacy to better manage diabetes. 124. Haemulon aurlineatum, A reproductive analysis of sex ratios in Tomtate Taylor Avery, Department of Marine Biolog A reproductive study on spawning capable Tomtate, Haemulon aurolineatum, was conducted to determine if their sex ratios differ from 1:1 at different points throughout their reproductive cycle and characterize their spawning season off the coasts of South Carolina (USA). Analysis of 1,250 individuals collected from 2000‐2014 over an eleven month period (January‐November) demonstrated a significantly higher proportion of males in the population regardless of their stage in the reproductive cycle. These data also confirmed that Tomtate are multiple batch spawners with the main spawning season occurring from March to July. 125. Substellar Candidate Search using Spitzer's Enhanced Imaging Products (SEIP) APPENDIX F Christina Mueller, Department of Physics and Astronomy For about 20 years, research into distant, faint objects, such as exoplanets, has increased. Many systems of interest are challenging to observe due to the presence of image‐obscuring interstellar dust. Dusty regions can now be viewed at longer wavelengths in the infrared at 3.6 um and 4.5 um, which are nearly free of deleterious influences of dust. Images at those wavelengths for seven nebulae were chosen at random from available imagery. Images were analyzed using the Spitzer Enhanced Imaging Product's source list search powered by Gator, which provides visual and spectral data. The relative flux for 45,000 sources was compared, and 140 sources with flux4.5 > flux3.6 are deemed candidates for further investigation. This selection criterion is a common indicator of substellar objects. 126. NASA Space Mission to Europa Christopher Andrews, Elise Krall, Sam Fink, and Jeremy Jones, Department of Physics and Astronomy Europa, a moon of Jupiter, has potential to increase our knowledge of icy satellites, but also of Earth.This moon, according to fly‐by surveys made by the Galileo and Voyager missions, may have a possible sub‐surface ocean. Due to the existence of this potential ocean, Europa could have a high probability of being habitable. We propose three main scientific goals to determine Europa’s habitability: identifying conditions necessary for surface formations by comparing old and new features, understanding the relationship between Europa’s chemical composition and possible life, and constraining the ice sheet thickness and characteristics of the subsurface environment. Our proposed mission will utilize an orbiter to gather data across the electromagnetic spectrum and a lander that will provide additional planetary surface data. Our proposed mission aims to add significantly to our knowledge of Europa while also providing a foundation for future explorations. 127. Jovian Interplanetary Mission to Europa (JIME) Naomi Hillegass1, Zach Sturman2, Annie Steele3 and Nathan Gunzenhauser3 1 Department of Mathematics 2 Department of Political Science 3 Department of Physics and Astronomy Europa, Jupiter’s smallest Galilean satellite, is an icy body known to have an ice surface several kilometers thick and an all encompassing ocean beneath. The presence of liquid water and the tidally caused internal energy makes Europa an enticing opportunity to look for extraterrestrial life. We propose a reconnaissance mission to study the habitability through surface evolution, internal structures, and Jovian system interactions. JIME requires both a radiation‐endurant orbiter and lander working in conjunction to one another. The mission will observe the transfer of energies, identify surface and subsurface compounds, and map the intricacies of Europa’s structure. Critical instruments to this mission includes radar, laser altimeters, and high APPENDIX F resolution cameras over multiple wavelengths. JIME will lay the groundwork for future subsurface missions to Europa in NASA’s continued search for life in our solar system. 128. Air pollution monitoring utilizing a low cost CubeSat Winslow DiBona1, Jenna Snow2, Leisha Lopez3, Sarenna Nath4 and Courtney Lawrence5 1 Department of Computer Science 2 Department of Health and Human Performance 3 Department of Physics and Astronomy 4 Deparment of Sociology and Anthropology 5 Department of Political Science As global temperatures rise due to increased industrialization around the world, monitoring air pollution has become a pertinent issue as people attempt to resolve the damage caused to the atmosphere. This presents a need for accessible monitoring in regions that contain factories and production plants. This paper proposes a cost‐efficient approach to gathering this data utilizing a CubeSat, smartphone, and a low altitude balloon. The CubeSat along with its payload will be launched in Decatur, Alabama and Huntsville, Alabama to study the presence of carbon monoxide, nitrogen dioxide, sulfur dioxide, ozone, and particulate matter. This data will be used to make a statistical analysis of the composition of the atmosphere above both cities, and to determine the compositional changes compared to previous studies in the regions. 129. The Ontogeny and Dentition of the Naked Goby Tasneem Dossaji, Department of Biology A recent study shows that there is an abrupt shift from microscopic to macroscopic organisms in the dietary composition of the naked goby Gobiosoma bosc. This study’s primary focus is to correlate the shift in diet to the possible shift in the physical dental characteristics of the sample size collected (n=30). A method of clearing and staining was used in order to observe the ontogeny and dentition of the samples. The number and size of teeth relative to body size was observed. The observations show that there is a positive correlation between body size (measured in standard length) and premaxilary tooth number (R2= 0.60). There was also slight positive correlation between the standard length and dentary tooth number count, but not nearly as strong (R2=0.34). It can be seen that there is a discrepancy between the development in premaxilary and dentary teeth and that there is more significant change in comparison to body size in the premaxilla compared to the dentary. 130. (Intentionally Blank) Nicolas E. Alcala, Joshua J. Mifflin, Loren E. Dupuis, Sarah Thibaudeau and Christine B. Kern. Department of Regenerative Medicine and Cell Biology, Medical University of South Carolina (Intentionally left blank) APPENDIX F 131. Investigating the Invasive History of Gracilaria vermiculophylla using molecular markers Sarah J. Shainker, Stacy A. Krueger‐Hadfield and Erik E. Sotka, Department of Biology The seaweed Gracilaria vermiculophylla spread from its native region, the northwest Pacific Ocean, to Europe and North America. A single nucleotide polymorphism (SNP) was used to investigate the invasion’s source and pathways of spread. A SNP is a variant at a single nucleotide of DNA. The SNP of interest exhibited either cytosine (C) or thymine (T). Preliminary data suggested that the SNP could differentiate between populations based on their geographic origin. The SNP was isolated with a restriction enzyme that cut the DNA only when the nucleotide of interest was T. Resulting DNA fragments, visualized using gel electrophoresis, indicated the nucleotide present. Most individuals from the species’ native range exhibited C’s, except for individuals from northern Japan, which exhibited T’s. Most individuals in the non‐
native range also exhibited T’s. These results suggest that the regions of northern Japan and the Sea of Japan are the source of the species’ spread. 132. Believe it or not: not all Six‐Membered Ring Molecules are not in Chair Conformation. Colin Cotter, Gamil A. Guirgis and Clyde R. Metz, Department of Chemistry and Biochemistry The structural parameters for [Si(CH3)2O]3 have been determined from quantum mechanics calculations (I‐IF, MP2, B3LYP) using different basis sets up to 6‐311++G(2d,2pd). These theoretical parameters were compared to the experimental x‐ray structure for the solid of [Si(CH3)2013. The short internuclear distances are consistent with delocalization in the ring. Natural Bond Orbital (NBO) results confirm the contribution of significant delocalization of the oxygen lone pair electrons. Semi‐empirical calculations which do not include d‐orbitals also reveal a planar structure. For the hexamethyl and possibly the hexachloro derivatives, all conformations other than the planar structure lead to severe steric interactions between substituents. Interestingly, when the oxygen atom is replaced by NH group in 1,3,5‐
cyclotrisilazane, the conformation changed to the twisted boat conformation which is contrary the that the boat conformer is a transition state as in the case of the carbon analogue.

2014-2015 Annual Report - School of Sciences and Mathematics

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