New Glucose Measurement Technology

discovery
A BETTER WAY TO MEASURE GLUCOSE
FOR DIABETICS
The next generation for
diabetic monitoring:
painless measurement
The World Health Organization estimates that diabetes mellitus is the
eighth largest cause of death globally with the diseases fastest growth
rate in the developed regions of the world. There are 29.1 million
Americans living with diabetes which leads to a 50% higher risk of death
in adults.
Monitoring blood glucose is one crucial aspect of diabetes management.
Currently, monitoring blood glucose requires direct FDA-approved
measurement from a blood sample, using a lance, strips and glucometer.
This inconvenient and invasive monitoring technique often discourages
patients from making the frequent measurements needed for careful
regulation of glucose.
For the professional: Glucose Breathalyzer
Measures glucose concentration in exhaled breath. Ideal for screening sessions
in clinics, hospitals, ER centers, doctor’s offices and schools.
 Developed at Purdue University, USA, patent pending
For the patient: Disposable biosensor strips
Measures glucose concentration in saliva samples placed on disposable
biosensor strips. Potentially ideal for personal use as an alternative to blood
glucometers, lances and strips.
 Developed at Arizona State University, USA, U.S. patent 8,815,178
NEW INNOVATIONS FOR SAFE, ACCURATE AND
PAINLESS DIABETES MANAGEMENT
BREATH GLUCOSE MONITOR
SALIVA GLUCOSE METER
Glucose is a non-volatile molecule found in exhaled breath
condensates. Accurately measuring the concentration of
glucose in exhaled breath may allow non-invasive
estimation of glucose concentration in blood, which in turn
could be used for routine monitoring of the blood glucose
concentration in diabetic patients. Currently, there is no
commercially available device to collect exhaled breath
condensate and measure its glucose level.
Glucose is present in saliva at low concentrations. The
device allows trace fluid samples from a biological surface to
be obtained for electrochemical analysis and the subsequent
detection of analytes. The device can be used to collect fluid
from the mouth and for such samples to be subsequently
processed to detect glucose, a metabolic product in saliva,
using disposable biosensor strips.
HO W I T W O R KS The device has a collections chamber
HO W I T W O R KS The glucose monitor consists of a
breath condensing unit that monitors the temperature,
volume, and glucose concentration of exhaled breath along
with a condenser for background air. The glucose
concentration of exhaled breath condensate is corrected
for the humidity and glucose concentration of background
air in order to deliver more reliable measurements
compared to those of similar technologies. The blood
glucose concentration is calculated from its correlation with
the corrected glucose concentration in the exhaled breath
condensate with fluorescent spectroscopy.
A D V A NT AG E S
The advantages of this technology are
that the sensor system does not require blood samples
while simultaneously reducing measurement complications
that may result from humidity and glucose in air.
containing an absorbent hydrogel material with a connected
microfluidic channel. A sensing chamber is connected to the
channel that allows saliva samples to be extracted. The
sensing chamber contains an enzyme that detects the
glucose through electrochemistry. The glucose concentration
is calculated from the current generated in the biosensor
strip.
A D V A NT AG E S
The advantages of this technology are
that the sensor is quick, easy to use, does not require blood
samples and operates in a similar way to the current FDAapproved blood glucose strips. The technique is very
sensitive and only needs very small saliva samples. The
strips can be manufactured in high volumes at low cost using
screen-printed thick films.
Available for Immediate License
.
For additional information contact:
Dr. Michael Kayat
Vice President
mkayat@tekcapital.com
+1 305 200 3450 x 303 (office)
+1 727 242 3786 (mobile)
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