Kangaroo Mother Care - International Initiative for Impact
Transcription
Kangaroo Mother Care - International Initiative for Impact
Kangaroo Mother Care Prof. Somashekhar Nimbalkar Professor of Pediatrics and Chairman (Research) Pramukhswami Medical College, Karamsad –Anand- Gujarat Governing Council Member 2013 and 2014 (National NNF) West Zone IAP PALS Coordinator (2009-2010) West Zone Coordinator (BNCRP) 4 million newborn deaths - When? Up to 50% of neonatal deaths are in the first 24 hours 75% of neonatal deaths are in the first week – 3 million deaths Source: Lawn JE et al Lancet 2005, Based on analysis of 47 DHS datasets (1995-2003), 10,048 neonatal deaths) Lancet 2010; 375: 1969–87 Lancet 2010; 375: 1969–87 8·795 million child deaths in 2008 3.6 million neonatal deaths Lancet 2010; 375: 1969–87 1.2906 million neonatal deaths Estimated numbers of deaths by cause in children younger than 5 years in South East Asia All cause by age Bangladesh Bhutan Burma India Indonesia Maldives Nepal North Korea Sri Lanka Thailand Timor-Leste <5 years 182 936 1199 123 562 1 829 826 173 036 163 36 822 18 246 6239 14035 3924 0–27 days 113 884 523 49 119 1 003 767 80 140 90 22 578 9373 3165 9971 1901 1–59 months 69 053 676 74 443 826 060 92 895 73 14 244 8873 3073 4064 2023 Estimated numbers of deaths by cause in children younger than 5 years in South East Asia All cause by age Bangladesh Bhutan Burma India Indonesia Maldives Nepal North Korea Sri Lanka Thailand Timor-Leste <5 years 182 936 1199 123 562 1 829 826 173 036 163 36 822 18 246 6239 14035 3924 0–27 days 113 884 523 49 119 1 003 767 80 140 90 22 578 9373 3165 9971 1901 1–59 months 69 053 676 74 443 826 060 92 895 73 14 244 8873 3073 4064 2023 Neonatal deaths contribute to about 40% deaths of the total under 5 child mortality. Deaths in children <5 y is 7.6 million 3.07 Million deaths in 0-27 days Global, regional, and national causes of child mortality: an updated systematic analysis for 2010 with time trends since 2000 Estimated numbers of deaths by cause in 2010 Estimated number (UR; millions) Neonates aged 0–27 days Preterm birth complications Intrapartum-related complications Sepsis or meningitis Pneumonia* Congenital abnormalities Other disorders Tetanus Diarrhoea† Children aged 1–59 months Other neonatal disorders Pneumonia* Diarrhoea† Malaria Injury Meningitis AIDS Measles 1·078 (0·916–1·325) 0·717 (0·610–0·876) 0·393 (0·252–0·552) 0·325 (0·209–0·470) 0·270 (0·207–0·366) 0·181 (0·115–0·284) 0·058 (0·020–0·276) 0·050 (0·017–0·151) 1·356 (1·112–1·581) 1·071 (0·977–1·176) 0·751 (0·538–1·031) 0·564 (0·432–0·709) 0·354 (0·274–0·429) 0·180 (0·136–0·237) 0·159 (0·131–0·185) 0·114 (0·092–0·176) Amount of Reduction (%) in all-cause neonatal mortality or evidence morbidity/major risk factor if specified (effect range) Evidence of efficacy for interventions during Postnatal periods Resuscitation of newborn baby IV Breastfeeding V Prevention and management of hypothermia IV Kangaroo mother care (low birth weight infants in health facilities) 6–42% 55–87% 18–42% Incidence of infections: 51% (7– IV 75%) V – Best evidence -------------------- I –Poor Evidence Lancet 2005; 365: 977–88 Amount of Reduction (%) in all-cause neonatal mortality or evidence morbidity/major risk factor if specified (effect range) Evidence of efficacy for interventions during Postnatal periods Resuscitation of newborn baby IV Breastfeeding V Prevention and management of hypothermia IV Kangaroo mother care (low birth weight infants in health facilities) 6–42% 55–87% 18–42% Incidence of infections: 51% (7– IV 75%) V – Best evidence -------------------- I –Poor Evidence Lancet 2005; 365: 977–88 Kangaroo Joey – Is it Magic? Kangaroo Mother Care Kangaroo mother care is care of infants carried skin-to-skin with the mother. Components of KMC Key Components are: early, continuous and prolonged skin-to-skin contact between the mother and the baby (Kangaroo Position); exclusive breastfeeding ; Skin to skin contact promotes lactation and facilitates the feeding interaction. Prerequisites of KMC Support to the mother in hospital and at home A mother cannot successfully provide KMC all alone. Mother requires • counselling along with supervision from care-providers, • assistance and cooperation from her family members. Post-discharge follow up KMC is continued at home after early discharge. Regular follow up and access to health providers is crucial to ensure safe and successful KMC at home. Brief History of KMC Began this method in 1978 in response to the high burden of Low Birth Weight babies and paucity of resources at the Instituto Materno Infantil (IMI) in Bogota, Colombia Rey ES, Martinez HG. Manejo racional del niño prematuro. In: Curso de Medicina Fetal, Universidad Nacional, Bogotà, Colombia, 1983. 137-151 Dr. Edgar REY SANABRIA COMPARATIVE STATISTICS BEFORE & AFTER INTRODUCTION OF KMC AT COLOMBIA Weight Categories Before KMC (g.) 1975 – 1976 501 – 1000 0 After KMC 1979-1981 72 1001-1500 27 89 Abandoned Babies 34 10 Benefits of KMC Breast feeding Thermal Control Early Discharge Decreased Mortality Reduced neonatal pain Improved Maternal Attachment Decreased Maternal depression Neonatal Transport Decreased Apnea Decreased Infections Better Neurodevelopment KMC results in increased breastfeeding rates as well as increased duration of breastfeeding Study Author Year Outcome KMC Control RCT Charpak 1994 Partial or excl breastfeeding at 1 month 6 months 1 year Partial or excl breastfeed at 3 mo Excl breastfeeding at discharge Daily volume Daily feeds Breastfeeding at 6 weeks Breastfeeding at discharge Daily feeds (34 weeks of Gest Age) Breastfeeding at: discharge 1 month Daily volume at 4 weeks Excl breastfeeding at discharge 93% 70% 41% 82% 88% 640 ml 12 55% 77% 12 90% 50% 647 ml 37% 78% 37% 23% 75% 70% 400 ml 9 28% 42% 12 61% 11% 530 ml 6% RCT RCT Charpak Cattaneo Schmidt 1997 1998 1986 Whitelaw Wahlberg Syfrett BlaymoreBier Hurst et al. 1988 1992 1993 1996 1997 Benefits of KMC Breast feeding Thermal Control Early Discharge Decreased Mortality Reduced neonatal pain Improved Maternal Attachment Decreased Maternal depression Neonatal Transport Decreased Apnea Decreased Infections Better Neurodevelopment KMC provides effective thermal control with a reduced risk of hypothermia. X-skin to skin at birth and continuing O- Skin to skin and transfer to warmer – Warmer from beginning Journal of Nurse-Midwifery Vol. 25, No. 1, Jan/Feb 1980 Body temp and oxygen consumption during skin-to-skin care in stable preterm infants weighing less than 1500 gms During skin-to-skin care the mean rectal temperature was 0.2 ° C (p <0.0 I) and the peripheral skin temperature was 0.6 ° C (p <0.01) higher than during the preceding hour in the incubator. Back in the incubator, body temperatures returned to values recorded before skin-toskin care. Oxygen consumption during skin-to-skin care (6. I + 0.9 ml/kg per minute)was not significantly higher than in the incubator (5.8 + 0.8 ml/kg per minute) J Pediatr 1997;130:240-4 Randomised study of skin-to-skin versus incubator care for rewarming low risk hypothermic neonates STS care was at least as effective as incubator care for rewarming low-risk hypothermic neonates. Healthy fullterm infants cared for with STS by their mothers gain heat when their body temperature is less than 36·3 C, but lose heat to the mother when the body temperature has increased to 37 C. THE LANCET • Vol 352 • October 3, 1998 Benefits of KMC Breast feeding Thermal Control Early Discharge Decreased Mortality Reduced neonatal pain Improved Maternal Attachment Decreased Maternal depression Neonatal Transport Decreased Apnea Decreased Infections Better Neurodevelopment KMC managed babies had better weight gain, earlier hospital discharge and higher excl. breast-feeding rates. Randomized control trial in 28 neonates(<1500 gms) . The Kangaroo group (n=14) was subjected to KMC of at least 4 hours per day in not more than 3 sittings. The babies received Kangaroo Care after shifting out from NICU and at home. The control group (n=14) received only standard care (incubator or open care system). Neonates in the KMC group demonstrated better weight gain after the first week of life (15.9 + 4.5 gm/day vs. 10.6 + 4.5 gm/day in the KMC group and control group respectively p<0.05) and earlier hospital discharge (27.2 + 7 vs. 34.6 + 7 days in KMC and control group respectively, p<0.05). Ramnathan et al Indian J Pediatr 2001; 68 (11) 9 1019-1023 KMC improves growth low birth weight infants. 206 neonates with birth weight <2000 g were randomized into (KMC-103) and control group (CMC: 103) The KMC babies had better average weight gain per day (KMC: 23.99 g vs CMC: 15.58 g, P<0.0001). The weekly increments in head circumference (KMC: 0.75 cm vs CMC: 0.49 cm, P = 0.02) and length (KMC: 0.99 cm vs CMC: 0.7 cm, P = 0.008) were higher in the KMC group. A significantly higher number of babies in the CMC group suffered from hypothermia, hypoglycemia, and sepsis. SUMAN RAO et al Indian Pediatrics 2008 Vol 45 Benefits of KMC Breast feeding Thermal Control Early Discharge Decreased Mortality Reduced neonatal pain Improved Maternal Attachment Decreased Maternal depression Neonatal Transport Decreased Apnea Decreased Infections Better Neurodevelopment ‘Kangaroo mother care’ to prevent neonatal deaths due to preterm birth complications Meta-analysis of three RCTs commencing KMC in the first week of life showed a significant reduction in neonatal mortality Joy Lawn et al in IJE 2010;39:i144–i154 ‘Kangaroo mother care’ to prevent neonatal deaths due to preterm birth complications A meta-analysis of three observational trials comparing KMC with standard incubator care showing cause specific mortality effect for babies of birthweight <2000 g Joy Lawn et al in IJE 2010;39:i144–i154 ‘Kangaroo mother care’ to prevent neonatal deaths due to preterm birth complications Meta-analysis of five RCTs comparing KMC with CMC showing effect on severe morbidity (severe pneumonia, sepsis, jaundice and other severe illness) for babies of BW <2000 g . KMC was started in first week of life. Joy Lawn et al in IJE 2010;39:i144–i154 ‘Kangaroo mother care’ to prevent neonatal deaths due to preterm birth complications Major mortality reduction [51% (18–71%)] for neonatal mortality in babies with birthweight <2000 g, with even greater reductions in serious morbidity Recommend the routine use of KMC for all babies <2000 g as soon a they are stable. Up to half a million neonatal deaths due to preterm birth complications could be prevented each year if this intervention were implemented at scale. Joy Lawn et al in IJE 2010;39:i144–i154 Benefits of KMC Breast feeding Thermal Control Early Discharge Decreased Mortality Reduced neonatal pain Improved Maternal Attachment Decreased Maternal depression Neonatal Transport Decreased Apnea Decreased Infections Better Neurodevelopment Kangaroo Care is effective in decreasing pain response in preterm neonates PIPP scores across the first 90 sec from the heel lancing procedure were significantly lower(0.002<P<0.04) than by 2 points in the KC condition (Preterm>32 weeks) Arch Pediatr Adol Med 2003; 157 : 1084 -1088 KMC is effective in decreasing pain response in very preterm(28-32 weeks) neonates PIPP scores at 90 seconds post lance were significantly lower in the KMC condition (8.871 (95%CI 7.852–9.889) versus 10.677 (95%CI 9.563–11.792) p < .001). Time to recovery was significantly shorter, by a minute(123 seconds (95%CI 103–142) versus 193 seconds (95%CI 158–227). Facial actions were highly significantly lower across all points in time reaching a two-fold difference by 120 seconds post-lance and heart rate was significantly lower across the first 90 seconds in the KMC condition. BMC Pediatrics 2008, 8:13 • PIPP score was significantly low in KMC group • KMC even for a short duration of 15 minutes prior to the procedure and continuing during the heel prick has pain reducing benefits • Preterm neonates >32 weeks GA can benefit from short duration KMC to decrease pain from heel prick procedure Benefits of KMC Breast feeding Thermal Control Early Discharge Decreased Mortality Reduced neonatal pain Improved Maternal Attachment Decreased Maternal depression Neonatal Transport Decreased Apnea Decreased Infections Better Neurodevelopment KMC Facilitates Mother Baby Attachment in Low Birth Weight Infants 16 month period 110 neonates( 35 weeks, 1-69 kg) were randomized into KMC group and CMC group The duration of hospital stay was significantly shorter in the KMC group (3.56±0.57 days) compared to control group (6.80±1.30 days). The total attachment score (24.46±1.64) in the KMC group was significantly higher than that obtained in control group (18.22±1.79, p<0.001). Mothers were significantly more involved in care taking activities and spent more time beyond usual care taking. They went out without their babies less often. They derived greater pleasure from their babies. Indian J Pediatr 2008; 75 (1) : 43-47 Benefits of KMC Breast feeding Thermal Control Early Discharge Decreased Mortality Reduced neonatal pain Improved Maternal Attachment Decreased Maternal depression Neonatal Transport Decreased Apnea Decreased Infections Better Neurodevelopment Effect of KMC on Postpartum Depression In 177 low-income mothers with their preterm infants 66 mothers (37.3%) had depression and it decreased to 30 (16.9%) after KMC intervention; p<0.0001. None developed PPD during the Kangaroo stay. KMC may lessen maternal depression 2008 Journal of Tropical Pediatrics Vol. 55, No. 1 Benefits of KMC Breast feeding Thermal Control Early Discharge Decreased Mortality Reduced neonatal pain Improved Maternal Attachment Decreased Maternal depression Neonatal Transport Decreased Apnea Decreased Infections Kangaroo Transport Instead of Incubator Transport 11 premature infants were transported in Heidelberg, Germany, in the kangaroo position with their mothers or female nurses when parents were not available. In Wernigerode, Germany 20 preterm and term infants were transported in the kangaroo position by their mothers, the father, or one of the authors. Two transports were by helicopter , rest by ambulance. Pediatrics 2004;113;920-923 Gestational age Weight at transport Age at transport Distance of transport Time for transport Range 26–41 wk 1220–3720 g 1 h to 79 d 2–400 km 10–300 min Median 35 wk 1970 g 17 d 35 km 40 min Kangaroo Transport Instead of Incubator Transport Kangaroo transport might be considered as a safe, effective, and inexpensive method of transport, promoting parent-infant bonding Pediatrics 2004;113;920-923 Benefits of KMC Breast feeding Thermal Control Early Discharge Decreased Mortality Reduced neonatal pain Improved Maternal Attachment Decreased Maternal depression Neonatal Transport Decreased Apnea Decreased Infections Better Neurodevelopment Reduces Apnea A dramatic drop in the frequency of clinically evident episodes of obstructive apnea and/or bronchoaspiration. Pediatrics 1997;100:682– 688 Regular Breathing patterns with a decrease of apneic episodes and periodic respiration are more frequent in conventional care J Perinatology 1991 , 11: 216-226 Benefits of KMC Breast feeding Thermal Control Early Discharge Decreased Mortality Reduced neonatal pain Improved Maternal Attachment Decreased Maternal depression Neonatal Transport Decreased Apnea Decreased Infections Better Neurodevelopment Kangaroo mother method: randomised controlled trial of an alternative method of care for stabilised low-birthweight infants. Maternidad Isidro Ayora Study Team Lancet. 1994;344:782–785 Kangaroo Mother Vs Traditional Care for Newborn Infants <2000 Grams: A RCT The proportions of mild to moderate infectious episodes that could be treated as on an OPD basis were 6.7% and 2.8% in the KMC and control groups, respectively (P = .019). Proportion of nosocomial infections after eligibility and before primary discharge was higher in the control group (kangaroo, 3.8%; control, 7.8%, P = .026). The number of total infectious episodes that had to be treated in the hospital was lower in KMC although the difference was not statistically significant (kangaroo, 7.6%; control, 11%, P = .17). Pediatrics 1997;100:682– 688 Kangaroo Mother Vs Traditional Care for Newborn Infants <2000 Grams: A RCT Kangaroo infants’ infections were less severe, most of them requiring only ambulatory care. Traditional care infants had a higher number of nosocomial infections and greater need for inpatient care of their infections. Pediatrics 1997;100:682– 688 Benefits of KMC Breast feeding Thermal Control Early Discharge Decreased Mortality Reduced neonatal pain Improved Maternal Attachment Decreased Maternal depression Neonatal Transport Decreased Apnea Decreased Infections Better Neurodevelopment KMC: A method for protecting high-risk LBW and premature infants against developmental delay 431 low-birth-weight and premature infants (≤1801 g) were assigned randomly to KMC or Traditional Care. KMC infants had a higher IQ than those given traditional care (TC). The difference was most highly significant for infants who were • more premature (30–32 weeks of gestational age), • had required intensive care, and • had a diagnosis of doubtful or abnormal neurological development at 6 months Infant Behavior & Development 26 (2003) 384–397 Comparison of KMC and Traditional Care: Parenting Outcomes and Preterm Infant Development Pediatrics 2002;110;16-26 Mother–infant interactive behaviors at 37 weeks’ GA in KC and control subjects. *P .05; ***P .001. Comparison of KMC and Traditional Care: Parenting Outcomes and Preterm Infant Development Pediatrics 2002;110;16-26 KC: mean: 96.39; KC: mean: 85.47; controls: mean: 91.81 controls: mean: 80.53 MDI and PDI scores of KC and control premature infants born at high and low medical risk. **P .01. Benefits of KMC Breast feeding Thermal Control Early Discharge Decreased Mortality Reduced neonatal pain Improved Maternal Attachment Decreased Maternal depression Neonatal Transport Decreased Apnea Decreased Infections Better Neurodevelopment Acta Pediatrica 2010 Nyquist et al Preterm infants should be considered extero-gestational foetuses needing KMC to promote maturation. After the uterus, maternal ⁄ parental–infant SSC is the expected evolutionary environment for development. All intrapartum and postnatal care should adhere to a paradigm of non-separation of infants and their parents. Kangaroo Mother Care should be used for warming, comfort, physiological and psychological benefits, growth, development, and the psychosocial needs of the family, and to promote lactation, breastfeeding initiation and longer breastfeeding duration The KP is the preferred routine place for care, beginning at birth, taking into consideration the physiological and behavioral state of the infant and parent; it is possible that KMC may contribute to the infant’s stabilization. Removal from this place of care should be for specific reasons only. Kangaroo Mother Care should be used for transfer of the infant to the neonatal unit after birth (when appropriate), within the hospital, and between hospitals Most nursing and medical procedures can be performed with the infant in KP, day and night. C Section? Ventilation? Short period on mother’s chest immediately in the operating room, if possible continued during post-op observation. Afterwards the mother is assisted with transportation to the NICU for as much KMC as possible without unjustified restrictions: Father - substitute acts as primary KMC provider. CPAP/ ventilator treatment does not constitute an obstacle to KMC Preterm on CPAP in KC position Baby on Ventilator KMC and phototherapy No need for separation Most nursing and medical care can be performed in KMC Tube feeding Suctioning Diaper change Blood samples Extubation Insert i.v. cannula Chest auscultation Twins, 26 weeks, ventilator care In affluence KMC is a valuable addition to infant care In financial constraints it is a precious gift In poverty it may be the only means of survival Prof. Attis Malan, South Africa Thank you