Join the team - Prostate Cancer Foundation
Transcription
Join the team - Prostate Cancer Foundation
J u n e 11 - 21, 2009 V o lu m e n o. 14 “ F RO M C o a s t to Coa st ” 14th Se a so n 1996 - 2 0 0 9 Join the team Fighting Can cer one home run at a time! The ques t to cure cancer Hall of Fame pitcher Nolan Ryan famously said, “A beautiful thing about baseball is that every once in a while, you come into a situation where you want to, and where you have to, reach down and prove something.” That’s the situation cancer researchers face every day—they want to prove that cancer can be beaten. Thanks in part to your support, they’re making great progress in doing just that. PCF an r & Chairm en - Founde Mike Milk Since 1993, the Prostate Cancer Foundation has accelerated development of more effective treatments, expanded our understanding of how cells become cancerous, produced new insights into areas like nutrition, and raised awareness of preventive activities. Most importantly, fewer men are dying—as much as 50% below projections made in the 1990s. By raising nearly $400 million directly, and guiding another $10 billion in funding from others—industry, government, philanthropists, people like you—the PCF has “Kept Dad in the Game.” More than 80 percent of prostate-cancer research leaders have been supported by the PCF, and a majority of drugs currently in the pipeline have our imprint on them. Jonathan Sim ons - Preside PCF nt and CEO But as more men live longer, more will be diagnosed—this year alone, 192,000 more. So we must continue to support these remarkable researchers. This is the PCF Home Run Challenge’s 14th season—a partnership with Major League Baseball (MLB), its players, managers and teams, as well as prominent sponsors, who raise awareness about prostate cancer worldwide and generate millions of dollars for crucial research. MLB players have averaged 135 home runs during the 60 Home Run Challenge games each year—they hit 143 last year. Please use the enclosed form or visit www.pcf.org to make a generous pledge that can help put an end to prostate cancer. Thank you! Mike Milken Chairman Jonathan Simons, MD President and CEO Home Run Challenge Sponsors How to parti ci pate •Fans attending games around the country contribute hundreds of thousands of dollars to fight prostate cancer. •Dedicated people like you make a donation for every home run hit in 60 Home Run Challenge games this year. •Safeway Corporation has raised more than $36 million for prostate cancer research through its annual June fundraising campaigns over the past eight years. Customers of Safeway stores (including Vons, Randalls, Tom Thumb, Pavilions, Genuardi’s, Carrs and Dominick’s) donate to the PCF at checkout counters, and with blue ribbon tear-off sheets and other in-store promotions. Safeway employees also contribute to the prostate cancer campaign. See page 2. Make a pledge at www.pcf.org One-A-Day and Major League Baseball will donate $10 to the Prostate Cancer Foundation for every strikeout in MLB games over the next three years. Visit www.pcf.org. P CF : L e veraging Million s into Billio ns How does the PCF grow million-dollar investments into billion-dollar medical advances? Financial Capital The $400 million raised directly by the PCF has attracted the infusion of more than $10 billion of additional funding for prostate cancer research—from government agencies, venture capital investments, the pharmaceutical and biotechnology sections, academic sectors and other philanthropists. Human Capital From what Forbes called “a research backwater” in 1993, the prostate cancer field—because of interest and funding generated by the PCF—has attracted more than 1,000 medical scientists into prostate cancer research. The PCF now plays a part in 90 percent of the field’s published research, a human-capital contribution exceeding $100 billion. Social Capital Fragmented and underfunded in 1993, the community of medical institutions actively pursuing a prostate cancer cure, and applying their findings to other deadly diseases, has grown to include virtually every major cancer research center in North America, and dozens more worldwide. In 1993, it was rare for men to get life-saving screening tests; today, because of PCF awareness programs, more than 60 percent do. Incalculable Social Capital 100 billion $ Human Capital 400 million $ Prostate Cancer Foundation 10 billion $ Financial Capital 6 Researchers Changing the Wor ld Breakthroughs Funded by PCF Donors Steven Balk, MD, PhD David Heber, MD, PhD Dan a Farb er / H arvard Can ce r Cen t e r UCLA Cen t er for H uma n Nutritio n Studying the mechanisms of resistance to new medications that are used to block the production of testosterone (cancer fuel) directly in the tumor sites. Studies may lead to prolonged drug usefulness and the definition of the next-generation treatments. Discovered that macrophage (specialized white blood cells that scavenge invading microbes and tissue debris) activation, a condition that promotes prostate cancer progression, is associated with obesity. Clinical investigations are underway to determine if dietary changes can reverse macrophage activation, establishing a marker for successful dietary intervention. Todd Golub, MD Howard Scher, MD Th e Broad In stitu te of MIT an d H arvard Unive rsit y Me morial Sloa n-Ke tte rin g C a n cer Cen te r Using some of the world’s most advanced screening biotechnologies to discover molecules that block the effects of genetic alterations in prostate cancer. These molecules could be featured in the next generation of treatments for prostate cancer. Developing two promising drug candidates for treatment of advanced prostate cancer. These oral medicines have few side effects and represent a new generation of treatments for patients who fail to respond to current therapies. Daniel Haber, MD, PhD Muneesh Tewari, MD, PhD H arvard Me dical S chool , Massachus e tts Gene ral H ospital Ca nce r Cen te r F re d H utchi n so n C a nc er Re se arch Cen ter a n d th e Un iv ersity of Washi ngto n Leading a research team that is refining a system to measure and identify circulating tumor cells in patient blood. This system may provide an early signal of prostate cancer progression, allowing doctors to better identify cancers and provide more informed treatments. Discovered small regulatory RNA molecules that circulate in the blood of prostate cancer patients. Testing is underway to validate a cancer-specific diagnostic test for prostate cancer that enables doctors to profile tumors and customize therapy. S afe w a y and Emp loyees A $36 Million Team. Each year Safeway and its affiliated stores host an in-store campaign for customers, vendors and employees to donate money for prostate cancer research. Since 2001, the company has raised more than $36 million. Surprise Visits to Safeway Tommy Lasorda makes surprise visits to Safeway stores during the Home Run Challenge to promote Safeway’s annual effort to raise funds for prostate cancer research. Mayoral Kickoff San Francisco Mayor Gavin Newsom helps launch Safeway’s annual prostate cancer fundraising drive in 2008. Ready for the Big Leagues? Keep on Truckin’ Safeway promotes its prostate cancer fundraising efforts in California by outfitting its delivery trucks with special graphics. Larree Renda, Safeway executive vice president, shows off her fastball by throwing out the first pitch at a San Francisco Giants game. Steve Burd, Safeway chairman, president and CEO, always brings a glove to HRC ball games. 2009 Schedule Thursday, June 11 Minnesota at Oakland Detroit at Chicago (AL) Cincinnati at Washington Pittsburgh at Atlanta Chicago (NL) at Houston San Francisco at Arizona PCF National League Player Representatives 12:35 1:05 4:35 1:00 1:05 12:40 Friday, June 12 Eric Byrnes Conor Jackson Chipper Jones Derrek Lee Jay Bruce Arizona Diamondbacks Arizona Diamondbacks Atlanta Braves Chicago Cubs Cincinnati Reds Todd Helton Jorge Cantu Lance Berkman Aaron Boone Miguel Tejada Colorado Rockies Florida Marlins Houston Astros Houston Astros Houston Astros Matt Kemp Jason Kendall Mike Cameron Carlos Delgado Chase Utley Los Angeles Dodgers Milwaukee Brewers Milwaukee Brewers New York Mets Philadelphia Phillies Philadelphia Phillies Nate McLouth Jack Wilson Brian Giles Aaron Rowand Albert Pujols John Russell Pittsburgh Pirates Pittsburgh Pirates San Diego Padres San Francisco Giants St. Louis Cardinals Washington at Tampa Bay Detroit at Pittsburgh St. Louis at Cleveland Cincinnati at Kansas City San Diego at Los Angeles (AL) Saturday, June 13 Boston at Philadelphia New York (NL) at New York (AL) Minnesota at Chicago (NL) Cincinnati at Kansas City Chicago (AL) at Milwaukee Houston at Arizona Sunday, June 14 Florida at Toronto Atlanta at Baltimore Seattle at Colorado San Diego at Los Angeles (AL) Tuesday, June 16 New York (NL) at Baltimore Toronto at Philadelphia Pittsburgh at Minnesota Milwaukee at Cleveland Tampa Bay at Colorado Oakland at Los Angeles (NL) Seattle at San Diego 7:38 7:05 7:05 7:10 7:05 7:05 4:10 12:05 6:10 3:05 5:10 1:07 1:35 1:10 12:35 7:05 7:05 7:10 7:05 6:40 7:10 7:05 PCF Team Managers A.J. Hinch Ken Macha Arizona Diamondbacks Milwaukee Brewers Bobby Cox* Jerry Manuel* Atlanta Braves Lou Piniella* Chicago Cubs Dusty Baker* Cincinnati Reds Clint Hurdle* Colorado Rockies Fredi Gonzalez* Florida Marlins Cecil Cooper Houston Astros Joe Torre* Los Angeles Dodgers New York Mets Charlie Manuel* Pittsburgh Pirates Bud Black* San Diego Padres Bruce Bochy* San Francisco Giants Tony La Russa* St. Louis Cardinals Manny Acta Washington Nationals *PCF Lead Manager Jason LaRue Nick Johnson St. Louis Cardinals Washington Nationals Ryan Zimmerman Washington Nationals Team representatives speak out about the importance of prostate cancer research and encourage fans to make a pledge. Some appear in public service announcements, while others donate autographed merchandise and participate in stadium events to raise awareness about this exciting way to join the search for a cure. Help keep dad in the game! PCF American League Player Representatives 2009 Schedule Wednesday, June 17 Washington at New York (AL) Toronto at Philadelphia Florida at Boston Milwaukee at Cleveland Detroit at St. Louis 7:05 7:05 7:10 7:05 7:15 Thursday, June 18 Cesar Izturis Nick Markakis Jason Bay David Ortiz Paul Konerko Baltimore Orioles Baltimore Orioles Boston Red Sox Boston Red Sox Chicago White Sox Chicago (AL) at Chicago (NL) New York (NL) at Baltimore Houston at Texas Tampa Bay at Colorado Oakland at Los Angeles (NL) 1:20 7:05 7:05 1:10 7:10 Friday, June 19 Atlanta at Boston Arizona at Seattle Texas at San Francisco 7:10 7:10 7:15 Saturday, June 20 Jim Thome Travis Hafner Chicago White Sox Cleveland Indians Curtis Granderson Brandon Inge Jose Guillen Detroit Tigers Detroit Tigers Kansas City Royals New York (AL) at Florida St. Louis at Kansas City Los Angeles (NL) at Los Angeles (AL) Texas at San Francisco Sunday, June 21 Mark Teahen Torii Hunter Joe Mauer Kansas City Royals Los Angeles Minnesota Twins Angels of Anaheim Derek Jeter Nick Swisher New York Yankees New York Yankees Toronto at Washington Tampa Bay at New York (NL) Baltimore at Philadelphia Atlanta at Boston New York (AL) at Florida Chicago (AL) at Cincinnati Cleveland at Chicago (NL) Milwaukee at Detroit St. Louis at Kansas City Houston at Minnesota Arizona at Seattle Los Angeles (NL) at Los Angeles (AL) Oakland at San Diego Texas at San Francisco Pittsburgh at Colorado 7:10 6:10 1:10 6:05 1:35 1:10 1:35 1:35 5:05 1:10 1:20 1:05 1:10 1:10 1:10 TBD 1:05 1:05 1:10 PCF Team Managers Dave Trembley Eric Chavez Nomar Garciaparra Jason Giambi Ken Griffey, Jr. Mike Sweeney Baltimore Orioles Oakland Athletics Oakland Athletics Oakland Athletics Seattle Mariners Seattle Mariners Boston Red Sox Terry Francona* Ozzie Guillen* Chicago White Sox Eric Wedge* Visit us online and make a pledge! www.PCF.org Carlos Pena Michael Young Scott Rolen Vernon Wells Tampa Bay Rays Texas Rangers Toronto Blue Jays Toronto Blue Jays Cleveland Indians Jim Leyland Detroit Tigers Trey Hillman Kansas City Royals Mike Scioscia* Los Angeles Angels of Anaheim *PCF Lead Manager Ron Gardenhire* Minnesota Twins Joe Girardi New York Yankees Bob Geren Oakland Athletics Don Wakamatsu Seattle Mariners Joe Maddon* Tampa Bay Rays Ron Washington* Texas Rangers Cito Gaston Toronto Blue Jays Home Run Challenge HOme Run Leaders All -Time HRC Leaders Team Player Home Runs Eric Karros 15 Retired Sammy Sosa 15 Retired Team Juan Gonzalez 9 Retired Todd Helton 9 Colorado Rockies Ken Griffey, Jr. 13 Seattle Mariners Phil Nevin 9 Retired Alex Rodriguez 13 New York Yankees Mike Piazza 9 Retired Adam Dunn 12 Washington Nationals Frank Thomas 9 Retired Barry Bonds 11 Inactive Larry Walker 9 Retired Pat Burrell 11 Tampa Bay Rays Jason Giambi 11 Oakland Athletics Alfonso Soriano 8 Chicago Cubs Gary Sheffield 8 New York Mets Rafael Palmeiro 8 Retired Richie Sexson 11 Retired Raul Mondesi 8 Retired Shawn Green 11 Retired Manny Ramirez 11 Los Angeles Dodgers Tony Clark 10 Arizona Diamondbacks Javier Lopez 8 Retired Chipper Jones 8 Atlanta Braves Jim Edmonds 10 Retired Torii Hunter 8 Los Angeles Angels Luis Gonzalez 10 Retired Carl Everett 8 Retired Andruw Jones 10 Texas Rangers Jim Thome 10 Chicago White Sox Albert Belle 9 Retired Jeromy Burnitz 9 Retired J.D. Drew 8 Boston Red Sox Carlos Delgado 8 New York Mets Joe Crede 8 Minnesota Twins Jeff Bagwell 8 Retired All -Time Active HRC Leaders National League American League Adam Dunn 12 Washington Nationals Ken Griffey, Jr. 13 Seattle Mariners Manny Ramirez 11 Los Angeles Dodgers Alex Rodriguez 13 New York Yankees Tony Clark 10 Arizona Diamondbacks Todd Helton 9 Colorado Rockies Carlos Delgado 8 New York Mets J.D. Drew 8 Boston Red Sox Torii Hunter 8 Los Angeles Angels Chipper Jones 8 Atlanta Braves Gary Sheffield 8 New York Mets Pat Burrell 11 Tampa Bay Rays Jason Giambi 11 Oakland Athletics Andruw Jones 10 Texas Rangers Jim Thome 10 Chicago White Sox Joe Crede 8 Minnesota Twins Vladimir Guerrero 7 Los Angeles Angels Alfonso Soriano 8 Chicago Cubs Hideki Matsui 7 New York Yankees Garret Anderson 7 Atlanta Braves Jorge Posada 7 New York Yankees Carlos Beltran 7 New York Mets Eric Byrnes 7 Arizona Diamondbacks Troy Glaus 7 St. Louis Cardinals Carlos Lee 7 Houston Astros Aramis Ramirez 7 Chicago Cubs Matt Stairs 7 Philadelphia Phillies Marcus Thames 6 Detroit Tigers Scott Rolen 6 Toronto Blue Jays Magglio Ordonez 6 Detroit Tigers Justin Morneau 6 Minnesota Twins Brandon Inge 6 Detroit Tigers 836 National League 782 American League 1997 – 114 1998 – 127 1999 – 126 2000 – 160 2001 – 149 2002 – 126 2003 – 130 2004 – 132 2005 – 128 2006 – 153 2007 – 130 2008 – 143 Paul Konerko 7 Chicago White Sox Annual HRC Home Runs Player Home Runs Eric Chavez 6 Oakland Athletics Total = 1,618 The average annual home run total is 135. 1996 statistics not included. Hall of Fame Some of Major League Baseball’s greatest players participate in the Home Run Challenge, often joining the Road Trip team. The Incomparable Vin Scully Hall of Fame broadcaster Vin Scully spends time with the HRC Road Trip team. Hall of Fame players, managers and broadcasters who’ve participated in HRC events: Ernie Banks Marty Brennaman Dennis Eckersley Rich “Goose” Gossage Reggie Jackson Sandy Koufax Mr. October and Mr. Garvey Hall of Fame slugger Reggie Jackson (left) and Dodgers perennial All-Star Steve Garvey at a pregame ceremony. Little Joe Mike and Hall of Fame second baseman Joe Morgan review the HRC schedule. Tommy Lasorda Willie McCovey Joe Morgan Jim Palmer Frank Robinson Vin Scully Brooklyn Dodger Legend Don Newcombe is the only pitcher to win the Rookie of the Year and Cy Young Award in the same year (1949). Below, “Newk” spends time with Guggenheim’s Scott Minerd. ‘The Great One’ Signs Autographs He may be more comfortable slapping a hockey puck on the ice, but NHL hockey Hall of Famer Wayne Gretzky signed lots of baseballs for fans during the HRC Road Trip in 2005. Hall of Fame Hurlers Jim Palmer (above), Baltimore Orioles pitcher, autographs Bob Barth’s Home Run Challenge jersey. HRC Road Trip member Mike Zapolin (left) gets in an animated discussion with Dennis Eckersley. Frank Robinson and Larry Lucchino Hall of Famer Frank Robinson, (middle photo above, red jacket), meets the Guggenheim team. Above, Hall of Fame Dodgers' manager Tommy Lasaorda and Red Sox President and CEO Larry Lucchino swap stories before an HRC game. TA KE THE HOM E RUN CHALLENGE QUIZ Home Run Challenge guests have witnessed some of the greatest moments in Major League Baseball over the past 14 years. See if you know the answers to these questions about some of those games. Question 1 Question 4 In 2004, Ken Griffey, Jr. hit his 500th career home run during a Home Run Challenge game. Where does Griffey rank on the all-time list of career home run hitters? San Diego Padres relief pitcher Trevor Hoffman was honored at a 2007 Home Run Challenge game. What milestone did this future Hall of Famer reach? Question 2 Question 5 In 2003, the Yankees and the Cubs played in Wrigley Field for the first time in more than 65 years. Roger Clemens pitched for the Yankees, hoping to earn his 300th career victory. Which player ruined his chances with a late-game pinch-hit home run? Sammy Sosa (A), Eric Karros (B), Moises Alou (C), Mark Grudzielanek (C), Lenny Harris (E). Who is this guy? And why have Chief Justice John Roberts (A), Dodgers Manager Joe Torre (B), and Cardinals Manager Tony La Russa (C) taken photos with him? Question 3 Hall of Fame Dodgers pitcher Sandy Koufax hurled four no-hitters in his career. During a 2003 HRC game, the Houston Astros no-hit the New York Yankees. How many Astros pitchers were used to complete the no-hitter? B A C See page 12 for answers. qu iz a nswer s Answer 1 Answer 4 Ken Griffey, Jr. ranks 5th on the all-time home run list. With 615 home runs (as of May 20, 2009), he trails only Barry Bonds (762), Hank Aaron (755), Babe Ruth (714) and Willie Mays (660). He is tied for second on the all-time HRC home run list (see page 16). San Diego pitcher Trevor Hoffman earned his 500th career save in June 2007. Now pitching for the Milwaukee Brewers, Hoffman has recorded 564 saves and has a career ERA of 2.75 over 17 seasons. Answer 2 Answer 5 Eric Karros. Answer 3 Six Houston Astro’s pitchers combined to no-hit the New York Yankees—the most pitchers to ever participate in a no-hitter. Mike’s assistant Larry Shamhart has attended every Home Run Challenge Road Trip game since 1996, entertaining his traveling companions, hauling bags and making sure everyone has a great time. Thanks, Larry—we couldn’t do it without you! p r o g r ess again st P ros tate can c er 1993 2003 After two decades of supporting a broad range of medical research, Mike Milken establishes the PCF, originally called CaP CURE. Annual prostate cancer deaths fall well below expert predictions. Fast-track grant guidelines limit applications to five pages, and fund projects within 90 days. 2004 PCF Call-to-Action dinner in the Mansfield Room of the U.S. Senate. The PCF’s first $4.5 million in research awards are presented. 1994 First Scientific Retreat brings together scientists, researchers, government officials and business leaders. Tenth annual Scientific Retreat in N.Y. The PCF plays key role in N.Y. Senate legislation allowing taxpayers to check off tax refund donations. A Call to Action published: a history of the PCF’s first decade. PCF-funded researcher Aaron Ciechanover awarded the Nobel Prize in chemistry. 1995 Fortune cover article calls Mike Milken “The Man Who Changed Medicine.” Four tissue banks and Gene & Family Studies Consortium created. 2005 First Las Vegas Golf Invitational hosted by Steve and Elaine Wynn. The PCF hosts FDA meeting to accelerate approval of oncology drugs. National Cancer Summit to develop action plans. 1996 Fortune magazine announces the PCF will be its official charity in 2005. The PCF publishes Report to the Nation, a guide for patients and their families. Number of PCF-funded projects reaches 1,200; $260 million raised since 1993. The PCF provides 46 researchers with Competitive Research Awards. Prostate cancer on the cover of Time and Fortune magazines. 2006 Therapy Consortium formed. Tenth anniversary: PCF Home Run Challenge. 1997 2007 Nutrition & Prostate Cancer published, detailing dietary guidelines. Jonathan Simons named CEO/President of the Prostate Cancer Foundation. Home Run Challenge raises $3 million for prostate cancer research. Three-pronged strategy introduced to provide larger, multiyear grants, support clinical trials and identify new biomarkers. 1998 PCF Young Investigator Awards start. THE MARCH in Washington and other cities draws hundreds of thousands to demand more government funding of cancer research. Funding doubles in five years. The Taste for Living Cookbook published. Senior PGA sponsorship begins. 1999 Mike Milken, Joe Torre and Senator Bob Dole testify before U.S. Senate for increased prostate-cancer research funding. Michael Jordan and Wayne Gretzky play the Las Vegas Golf Invitational. Safeway raises $10 million as part of its prostate cancer research funding program. 2008 The PCF reports a record year with $37.3 million in revenues; funds raised by the PCF since 1993 tops $350 million. The PCF issues 20 three-year Young Investigator Awards and eight multi-year Challenge Awards, making a total commitment of nearly $24 million to new research. New Prostate Cancer Strikeout Challenge launched with Bayer. 2000 Nine-year-old Winter Vinecki helps raise $125,000 for the PCF in honor of her father. U.S. News & World Report: “The [PCF’s] work is making a difference … [and] has led to 70 treatments now in human clinical trials.” Total government funding of prostate cancer has grown by a factor of 20 since 1993, to $550 million. The PCF and others succeed in requiring Medicare to pay for clinical trials. 2001 With PCF support, California is 14th state to pay for the cost of clinical trials. Safeway launches its prostate cancer campaign to support research. The PCF’s first Gourmet Games. 2002 First Indian Wells Tennis Tournament. Home Run Challenge named an official partner of Major League Baseball. 2009 The PCF funds $1 million for 10 one-year Creativity Awards. The PCF releases Nutrition, Exercise and Prostate Cancer, the latest science-based guidelines for prostate cancer prevention and survivorship. Marathon Hall of Famer and cancer survivor Bill Rodgers returns to the Boston Marathon to raise awareness for prostate cancer and the PCF’s Athletes for a Cure program. HOme Run challenge Funding PROSTATE CANCER RESEARCH FOR 14 YEARS Visit us online and make a pledge! www.PCF.org
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