FTFoS Symposium

Transcription

FTFoS Symposium

Sixth French-Taiwanese Frontiers of Science
FTFoS
Symposium
Margaux, France,
June 10 -13, 2013
CONTENTS
CONSORTIUM PRESENTATION................................................................................................................................................ 5
SYMPOSIUM PROGRAM............................................................................................................................................................... 7
LIST OF TAIWANESE OFFICIAL DELEGATES................................................................................................................10
LIST OF FRENCH OFFICIAL DELEGATES........................................................................................................................11
LIST OF TAIWANESE PARTICIPANTS.................................................................................................................................12
LIST OF FRENCH PARTICIPANTS.........................................................................................................................................13
PHOTOS OF PARTICIPANTS.....................................................................................................................................................14
SESSION ABSTRACTS.................................................................................................................................................................17
Session I : Physical Sciences................................................................................................................................ 17
HSIAO Pai-Yi ..................................................................................................................................................................................... 19
JIANG Hong-Ren .............................................................................................................................................................................19
MALLICK Kirone .............................................................................................................................................................................. 20
Session II : Applied Sciences................................................................................................................................................21
CHEN Kate Hui-Hsuan................................................................................................................................................................... 23
LIN Chih-Ping ................................................................................................................................................................................... 23
SIMOES Martine............................................................................................................................................................................... 24
Session III : Life Sciences........................................................................................................................................................25
COURCHAMP Franck .................................................................................................................................................................... 27
DING Tzung-Su ............................................................................................................................................................................... 27
MURIENNE Jérôme ........................................................................................................................................................................ 28
Session IV : Social Sciences / Humanities..................................................................................................................29
JOUVE Bertrand............................................................................................................................................................................... 31
CHAVALARIAS David ..................................................................................................................................................................... 31
LEE Zong-Rong................................................................................................................................................................................ 32
CURRICULUM VITAE (alphabetical order)....................................................................................................................33
B
BRAKENHIELM Ebba............................................................................................................................................................................. 35
C
CHAMPAGNE-LAVAU Maud................................................................................................................................................................ 36
CHAVALARIAS David............................................................................................................................................................................ 38
CHEN Hsuan-Yi ..................................................................................................................................................................................... 39
CHEN Kate Huihsuan ............................................................................................................................................................................40
CHIANG Chun-Fang.............................................................................................................................................................................. 42
CHIANG Yen-Sheng ............................................................................................................................................................................. 43
CHING Yung-Hao................................................................................................................................................................................... 44
CHU Chih-Yuan James........................................................................................................................................................................ 45
CHUNG Kuo-Fang.................................................................................................................................................................................. 46
CLAIR Sylvain.......................................................................................................................................................................................... 48
COURCHAMP Franck............................................................................................................................................................................ 49
D
DING Tzung-Su....................................................................................................................................................................................... 50
3
G
GAUFFRE Fabienne................................................................................................................................................................................ 51
GOSSE Charlie......................................................................................................................................................................................... 52
H
HSIAO Pai-Yi............................................................................................................................................................................................. 53
J
JIANG Hong-Ren.................................................................................................................................................................................... 54
JOUVE Bertrand..................................................................................................................................................................................... 55
K
KIM Junbeum.......................................................................................................................................................................................... 56
KUOCHEN Hao........................................................................................................................................................................................ 58
L
LAI Wen-Sung...........................................................................................................................................................................................59
LE COR Gwen.......................................................................................................................................................................................... 61
LEE Shih-Yu............................................................................................................................................................................................. 62
LEE Wei-Li .............................................................................................................................................................................................. 63
LEE Zong-Rong ..................................................................................................................................................................................... 64
LEVENEUR Sébastien.......................................................................................................................................................................... 65
LIAO Chien-Neng.................................................................................................................................................................................. 66
LIN Chih-Ping......................................................................................................................................................................................... 67
LIN Keng-Hui.......................................................................................................................................................................................... 68
LIN Shau-Ping........................................................................................................................................................................................ 69
LIN Thung-Hong.................................................................................................................................................................................... 70
M
MALLICK Kirone..................................................................................................................................................................................... 71
MURIENNE Jérôme............................................................................................................................................................................... 72
P
PEZO Valérie............................................................................................................................................................................................ 73
PRÉVOT Laurent ................................................................................................................................................................................... 74
S
SCIAMANNIA MARC ............................................................................................................................................................................ 75
SERRA Christophe................................................................................................................................................................................ 76
SHIH Chi-Tin............................................................................................................................................................................................ 77
SIMOES Martine.................................................................................................................................................................................... 79
STOCKHOLM Daniel............................................................................................................................................................................. 80
T
TREUSSART François.......................................................................................................................................................................... 81
V
VUILLERME Nicolas.............................................................................................................................................................................. 83
Y
YEANG Chen-Hsiang............................................................................................................................................................................ 85
ANNEXES ............................................................................................................................................................................................ 87
RELAIS DE MARGAUX PRESENTATION...........................................................................................................................89
ACCESS TO SYMPOSIUM VENUE .......................................................................................................................................90
LIST OF PAST TOPICS .................................................................................................................................................................91
4
THE FRENCH FRONTIERS OF SCIENCE
AND ENGINEERING CONSORTIUM
Since September 2009, a new organization has been set up to manage and coordinate all the FoS and FoE
programs. A group constituted with the ministries and the major French scientific institutions has created a
consortium acting as a steering committee and created a unit devoted to the logistics of the symposia. There
are two types of partnerships :
The “principal partners” in charge of one or more FoS or FoE programs :
• Ministère de l’enseignement supérieur et de la recherche
• Ministère des affaires étrangères
• Centre national de la recherche scientifique
• Conférence des directeurs d’écoles françaises d’ingénieurs
Liberté • Égalité • Fraternité
RÉPUBLIQUE FRANÇAISE
MINISTÈRE
DE L'ENSEIGNEMENT SUPÉRIEUR
ET DE LA RECHERCHE
The “associated partners” in charge of the common expenses to all programs (FoS unit, communication) :
• Institut de recherche pour le développement,
• Institut national de la santé et de la recherche médicale
• Institut Télécom
• Institut national de la recherche agronomique
• Institut national de la recherche en informatique et en automatique
• Institut des sciences et technologies de Paris - ParisTech
• Commissariat à l'énergie atomique
5
SYMPOSIUM PROGRAM
June 10 -13, 2013
Bordeaux, France
June 10, 2013 (Monday)
10.45~11:30
11:55~12:30
11:30~13:00
13:00~14:30
13:30~14:30
14:30~15:15
15:15~15:45
Transfer from Bordeaux Mérignac airport to hotel
“Relais de Margaux”
Transfer from Bordeaux Mérignac airport to hotel
“Relais de Margaux”
Registration & Hotel check in
Lunch at Hotel
Transfer from Bordeaux -Saint Jean station
to hotel “Relais de Margaux”
Registration & Hotel check in
Welcome coffee
Taiwanese participants
French participants
French participants
All participants
Opening ceremony
Ms Béatrice Chassaing
Deputy Consellor in charge of Scientific
Cooperation, Bureau français de Taipei
15:45~16:15
Ms. Catherine Bastien-Ventura
In charge of International Programs
Europe of Research
and International Cooperation Office
CNRS
All participants
Pr. Gilles Lerondel
UTT de Troyes, CDEFI
Dr. Ching-Long LU
Ambassador Taipei
Representative Office in France
16:15~16:30
16:30~16:50
16:50~17:10
17:10~17:30
17:30~18:30
18:30~18:50
19:00~20:30
Dr. Lih-Juann CHEN
President, National Tsing-Hua University
Photo Session
Physical Sciences
Arrow of the time
and non-equilibrium thermodynamics
General discussion
GP (session I) Flash talks
Dinner at Hotel
7
All participants
Chair (Taiwan)
Dr. Pai-Yi Hsiao
Speaker (Taiwan)
Dr. Hong-Ren Jiang
Speaker (France)
Dr. Kirone Mallic
All participants
General participants
All participants
SYMPOSIUM PROGRAM
June 11, 2013 (Tuesday)
09:30~09:50
Applied Sciences
09:50~10:10
Disaster prevention/prediction
10:10~10:30
10:30~11:00
11:00~12:00
12:00~12:20
12:20~14:00
Coffee break
General discussion
GP (session II) Flash talks
Lunch at Hotel
14:00~14:20
14:20~14:40
Life Sciences
Ecology, Biodiversity and evolution
14:40~15:00
15:00~15:30
15:30~16:30
16:30~17:10
17:10~18:40
Coffee break
General discussion
GP (session III-session IV) Flash talks
Poster session
Chair (Taiwan)
Dr. Hui-Hsuan Chen
Speaker (Taiwan)
Dr. Chih-Ping Lin
Speaker (France)
Dr. Martine Simoes
All participants
All participants
All participants
All participants
Chair (France)
Dr. Franck Courchamp
Speaker (Taiwan)
Dr Tzung-Su Ding
Speaker (France)
Dr. Jérôme Murienne
All participants
All participants
General participants
All participants
(Session I - Session IV)
17:10~18:40
Planning Group Meeting
19:00~21:30
Gala dinner
PGMs - French-Taiwanese
delegates
All participants
June 12, 2013 (Wednesday)
08:00~09:30
09:30~09:50
09:50~10:10
10:10~10:30
10:30~11:30
Breakfast and hotel check out
for French participants
Social Sciences /Humanities
Social Network:
quantitative analysis modeling and its impact
General discussion
8
French participants
Chair (France)
Dr. Bertrand Jouve
Speaker (Taiwan)
Dr. Zong-Rong Lee
Speaker (France)
Dr. David Chavalarias
All participants
SYMPOSIUM PROGRAM
Closing ceremony
11:30~11:45
11:45~13:15
13:15~16:30
14:00~15:00
17:30~18:30
17:30~19:00
19:00~21:00
Dr Marc Melka
Director, department of Asian Affairs, MESR
Dr. Tsung Tai LIN
General Director,
Department of International Cooperation, NSC
Lunch
Guided tour
Transfer from hotel “Relais de Margaux”
to Bordeaux Saint Jean station
to Bordeaux Saint Jean station
Free time for Taiwanese participants
Dinner at Hotel
All participants
All participants
All participants
French participants
French participants
June 13, 2013 (Thursday)
05:30~06:10
09:00~13:00
to Bordeaux Mérignac airport
Other departures
9
LIST OF TAIWANESE OFFICIAL DELEGATES
(alphabetical order)
Ms. Tong-En CHANG
• Secretary, Science and Technology Division
• Taipei Representative Office in France
• National Science Council
Dr. Lih-Juann CHEN
• President
• National Tsing Hua University
Ms. Xin-Yi CHENG
• Program Manager, Office of Global Affairs
Dr. Ruey-An DOONG
• Dean, College of Nuclear Science
Ms. Nathalie LAUVERGNIER
• Secretary, Science and Technology Division
Dr. Tsung Tai LIN
• Director General, Department of International Cooperation
Dr. Ching-Long LU
• Ambassador
Dr. Cheng-Tung TAO
• Program Director, Department of International Cooperation
Dr. Wei-Chung WANG
• Vice President, Office of Global Affairs
Dr. Wen-Guey WU
• Director, Science and Technology Division
10
LIST OF FRENCH OFFICIAL DELEGATES
(alphabetical order)
Ms. Catherine BASTIEN-VENTURA
• In charge of International Programs
• Europe of Research and International Cooperation Office
• CNRS
Ms. Béatrice CHASSAING
• Deputy Counsellor in charge of Scientific Cooperation
• Bureau français de Taipei
Mr. Dominique CHATTON
• In charge of scientific affairs Asia pacific
• DREIC
• Ministry of Higher Education and Research
Dr. Cécile MARGOSSIAN
• Director,
• Frontiers of Science Programs
• Frontiers of Science Consortium
Pr. Gilles LERONDEL
• Professor,
• UTT - Université de Technologie de Troyes
• CDEFI
Dr. Marc MELKA
• Director,
• Department of Asian Affairs
• DREIC
• Ministry of Higher Education and Research
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LIST OF TAIWANESE PARTICIPANTS
(session order)
Session I - Physical Sciences
PGM Hsuan-Yi CHEN
Chair Pai-Yi HSIAO
SP Hong-Ren JIANG
GP Wei-Li LEE
GP Keng-Hui LIN
GP Chi-Tin SHIH
National Central University
National Hsing Hua University
National Taiwan University
Academia Sinica
Academia Sinica
Tunghai University
Session II - Applied Sciences
PGM Chien-Neng LIAO
Chair Hui-Hsuan CHEN
SP Chih-Ping LIN
GP Chih-Yuan James CHU
GP Hao KUOCHEN
GP Shih-Yu LEE
National Hsing Hua University
National Taiwan Normal University
National Chiao Tung University
Academia Sinica
Session III - Life Sciences
PGM
SP
GP
GP
GP
Shau-Ping LIN
Tzung-Su DING
Kuo-Fang CHUNG
Yung-Hao CHING
Wen-Sung LAI
Tzu Chi University
Session IV - Social Sciences / Humanities
PGM
SP
GP
GP
GP
Thung-Hong LIN
Zong-Rong LEE
Chun-Fang CHIANG
Yen-Sheng CHIANG
Chen-Hsiang YEANG
Academia Sinica
Academia Sinica
Academia Sinica
Academia Sinica
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LIST OF FRENCH PARTICIPANTS
(session order)
Session I - Physical Sciences
PGM Fabienne GAUFFRE
SP
Kirone MALLICK
GP
Sylvain CLAIR GP
Marc SCIAMANNA
GP
François TREUSSART Institute of "Sciences Chimiques de Rennes" - CNRS
Institute of "Physique Théorique" - CEA
Institute "Matériaux microélectronique nanosciences de Provence" CNRS
Laboratory "Matériaux Optiques, Photonique et Systèmes" University of Lorraine
Laboratory of "Photonique quantique et moléculaire" CNRS-ENS Cachan
Session II - Applied Sciences
PGM
SP
GP
GP
GP
Charlie GOSSE
Martine SIMOES
Junbeum KIM
Sebastien LEVENEUR
Christophe SERRA
Laboratory for Photonics and Nanostructures - CNRS
Institute of Earth Physics of Paris - CNRS
CREIDD - CNRS
Laboratory "Sécurité des Procédés Chimiques" - INSA of Rouen
G2IP/ICPEES, CNRS University of Strasbourg
Session III - Life Sciences
PGM Valérie PEZO
Chair Franck COURCHAMP
SP
Jérôme MURIENNE
GP
Ebba BRAKENHIELM
GP
Daniel STOCKHOLM
GP
Nicolas VUILLERME
ISSB, CNRS & University Evry-Val-d’Essonne
Laboratory of Ecology, Systematic & Evolution CNRS and University of Paris Sud
Evolution and Biological Diversity laboratory - CNRS
Biomedical Research Institut Medical Faculty of Rouen - INSERM
Genethon-Unit 951 - INSERM-UEVE-EPHE
Laboratory "Age, Imagerie, Modélisation" (AGIM) CNRS and University Joseph Fourier
Session IV - Social Sciences / Humanities
PGM Laurent PREVOT
Laboratory Parole et langage - CNRS
Chair Bertrand JOUVE
MSH, IEA and Research Infrastructures - CNRS
SP
David CHAVALARIAS
Center of "Analyse et de Mathématiques Sociales
& Institute of "Systèmes Complexes de Paris Ile-de-France"
GP
Maud CHAMPAGNE-LAVAU Laboratory Parole et langage - CNRS
GP
Gwen LE COR"Transferts critiques et dynamique des savoirs" - University of Paris 8
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PHOTOS OF PARTICIPANTS
(session order)
SESSION I
PHYSICAL
SCIENCES
FabienneKirone Sylvain Marc François
GAUFFRE MALLICK CLAIRSCIAMANNA
TREUSSART
Hsuan-Yi
CHEN
Pai-Yi
Hong-Ren
Wei-Li
Keng-Hui
Chi-Tin
HSIAOJIANG LEE LIN SHIH
SESSION II
APPLIED
SCIENCES
Chien-Neng
LIAO
Charlie Martine JunbeumSébastienChristophe
GOSSE SIMOES KIM LEVENEURSERRA
Hui-Hsuan
Chih-Ping
Chih-Yuan James
Hao
Shih-Yu
CHEN
LIN
CHU KUOCHENLEE
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PHOTOS OF PARTICIPANTS
(session order)
SESSION III
LIFE
SCIENCES
Valérie FranckJéromeEbba Daniel
PEZO
COURCHAMP MURIENNEBRACKENHIELMSTOCKHOLM
Nicolas
VUILLERME
Shau-Ping
Tzung-Su
Kuo-Fang
Yung-Hao
Wen-Sung
LIN DING CHUNG CHINGLAI
SESSION IV
SOCIAL
SCIENCES /
HUMANITIES
LaurentBertrand David Maud Gwen
PREVOT
JOUVE
CHAVALARIAS CHAMPAGNE-LAVAU LE COR
Thung-Hong
LIN
Zong-Rong
Chun-Fang
Yen-Sheng
Chen-Hsiang
LEE CHIANGCHIANG YEANG
15
SESSION I
SESSION FIELD
PHYSICAL SCIENCES
SESSION TITLE
ARROW OF TIME
AND NON-EQUILIBRIUM THERMODYNAMICS
17
SESSION I
PHYSICAL SCIENCES
Arrow of time and non-equilibrium thermodynamics
Chair: Pai-Yi HSAIO
Department of Engineering and System Science, National Tsing Hua University
Fluctuation Theorems: Thermodynamics at Nanoscale
The 2nd law of thermodynamics, which states a spontaneous evolution of an isolated system towards a state
of maximum entropy and hence defines the one-way direction of time’s arrow, has been an unchanging principle of nature since its first formulation in 1850s by Clausius. Nonetheless, breakthroughs in non-equilibrium
thermodynamics starting in 1990s reveal that this law is increasingly blurred as the system size becomes
smaller. Evans and Searles formulate a microscopic version of the 2nd law, called “fluctuation theorem”,
which is applicable to small systems outside the thermodynamic limit including those that evolve far from
equilibrium. It describes quantitatively thermodynamic irreversibility from time-reversible equation of motion.
Later, Crooks proposed another fluctuation theorem which relates the distribution of work, evaluated over nonequilibrium trajectories, to the change of equilibrium free energy. This theorem implies the famous Jarzynski’s
equality and provides a new way to treat thermodynamics at the scale of single molecules. In this introductory
talk, I will speak about recent progresses in fluctuation theorems and discuss challenges in non-equilibrium
thermodynamics. These new concepts are extraordinarily important in today’s nano-world, particularly in understanding and gaining information in biomolecular science and nanotechnology.
Speaker: Hong-Ren JIANG
Institute of Applied Mechanics, National Taiwan University
Direction of Time from Microscopic World
What is time from microscopic world? Can we define time or the direction of time from the motion of a single
particle? In this presentation, I want to start from some relatively simple physical systems, such as Brownian
motion, microfluidics, and phoretic transport, to discuss how the concept of time naturally occurs in such systems. I will try to discuss the relations between the direction of time and nonequilibrium thermodynamics. The
realization of Maxwell's Demon in the single particle level and micro-heat engine based on phoretic motion
of Janus particles will be discussed to illustrate the idea how the energy transfers in the microscopic world.
19
Speaker: Kirone MALLICK
The Institut de Physique Théorique, CEA
Recent Developments in Non-equilibrium Statistical Physics
A complex system maintained out of equilibrium through its interactions with the environment will usually
evolve to a non-equilibrium steady state with a non-vanishing macroscopic current (a metal conductor subject
to a driving field in its bulk, or to a difference of potentials between its boundaries, provides a simple example).
Due to the presence of this stationary current, time-reversal invariance is violated. This is a situation which
lies beyond the realm of traditional thermodynamics and the principles of equilibrium statistical mechanics
do not apply. There exists no fundamental theory or framework (a la Gibbs-Boltzmann) that would allow us
to predict the value of the current and of its fluctuations from first principles. Nevertheless, during the last
two decades, substantial progress has been made towards a statistical theory of non-equilibrium systems.
The aim of this lecture is to explain some remarkable recent results valid for sytems far from equilibrium: the
Work Identities (Jarzynski, Crooks) and the Fluctuation Theorem (Cohen, Evans, Gallavotti and Morriss), that
quantify transient violations of the second principle. These seminal results can be applied to various physical
situations and put the emphasis of some mathematical objects, the large deviation functions that are expected to play for systems out of equilibrium a role akin to that of thermodynamic potentials. We shall illustrate
these concepts with some simple systems such as the Brownian ratchet model for molecular motors and the
asymmetric exclusion process, which is considered today as the paradigm of non-equilibrium physics.
20
SESSION II
SESSION FIELD
APPLIED SCIENCES
SESSION TITLE
DISASTER PREVENTION/PREDICTION
21
SESSION II
APPLIED SCIENCES
Disaster prevention/prediction
Chair: Kate Hui-Hsuan CHEN
Department of Earth Sciences, National Taiwan Normal University
Frontiers in Mitigation of Earthquake Induced Disasters
A thorough review of disaster losses issued by United Nations illustrates that direct losses from floods, earthquakes, and drought are in the range of $2.5 trillion. Awareness and improvement of natural hazard prevention, mitigation, and preparedness therefore, is necessary, to decrease a community’s vulnerability to natural
disasters. In this presentation a broad overview on the worst natural disasters over the past several decades
will be introduced. Haiti, Chile, and New Zealand all experienced major earthquakes in 2010, where the loss
of life and devastation in Haiti was much worse than other two countries, despite the smaller earthquake
magnitude. The differences among the three events will be compared and some social aspects that led to
the conditions in each country at the time of the earthquakes will be discussed as well. How do we improve
prevention of losses and how the scientists do, to better understand the generation mechanisms? I will focus
on some frontier research on earthquake disaster mitigation using real‐time seismic and GPS early warning,
and the most important scientific challenge that would have the potential to improve the early warning system.
Speaker: Chih-Ping LIN
Geo-Imaging and Geo-Nerve Laboratory, National Chiao Tung University
Geo-Nerve & Geo-Imaging for Natural Hazard Mitigation
Human body is born with a sophisticated nerve system, and seeing into the body is a state of practice by biomedical imaging. However, most infrastructures in our society, analogous to major organs in the human body,
do not have a health or early warning monitoring system. And seeing into the earth/structure is still a state of
the art. This talk introduces some recent efforts and projects in developing geo-nerve and geo-imaging techniques for monitoring and examination of infrastructure in the context of natural hazard mitigation.
The geo-nerve technique is realized by transmitting an electromagnetic pulse through a coaxial cable connected to a sensing waveguide and watching for reflections of this transmission due to changes in characteristic
impedance along the waveguide. Depending on the design of the waveguide and analysis method, the reflected signal can be used to “feel” various engineering parameters. Developments involved to adapt such a technique to various problems (e.g. landslide, bridge collapse, urban flooding, and reservoir sedimentation) are
introduced. The geo-imaging is achieved by geophysical prospecting using seismic wave, electrical current,
and radar. Some examples are given on how geo-imaging can be of value in hazard prevention. Difficulties
encountered in engineering scale and engineering environment will also be discussed.
23
Speaker: Martine SIMOES
The Institute of Earth Physics of Paris, CNRS
Seismic hazards: what can we learn from geology?
The identification of active (and therefore seismogenic) faults and the knowledge of their kinematics is crucial
for seismic hazards assessment. Even though geological and seismological investigations have been conducted in several active areas in the world, recent examples of devastating earthquakes on faults not previously
recognized as being active illustrate how critical such lack of knowledge can be. The 1999 ChiChi (Taiwan)
and the 2008 Wenchuan (China) earthquakes are two such examples.
One of the main issues in properly conducting such geological investigations lies in the difficult integration of observations at different spatial and temporal scales. Geologists classically describe the geometry of
mountain belts, inherited from a history of millions years of deformation, through geological cross-sections.
However, from there, they are usually unable to indicate which faults are presently active and how much
deformation these faults presently accommodate. On the other hand, geodesists and seismologists can only
observe deformation over a limited time-window of years to decades using GPS and seismological data, even
though the recurrence times of major earthquakes are of 100s to 1000s years. Observations at time scales
of 1s to 10s kyr are therefore needed to bridge the gap between long-term and short-term processes. To
this respect, the observation of landscapes at these time scales provides crucial indices of active tectonics.
Indeed, geomorphological markers of active deformation, such as incised river terraces or disrupted fans, are
used to track faults that are presently active and to decipher their kinematics over several earthquake cycles.
The assessment of seismogenic faults in an active area can therefore only properly be conducted through the
integration of geological observations over different time scales. Then, for the actual purpose of mitigating
seismic hazards, the Earth sciences community needs to put further efforts in communicating this knowledge
to populations and to policy-makers.
24
SESSION III
SESSION FIELD
LIFE SCIENCES
SESSION TITLE
ECOLOGY, BIODIVERSITY AND EVOLUTION
25
SESSION III
LIFE SCIENCES
Ecology, biodiversity and evolution
Chair: Franck COURCHAMP
Laboratory of Ecology, Systematic & Evolution CNRS – University of Paris Sud
Ecology is a fundamental and applied science aiming at understanding the interactions between living organisms and their environment. Living organisms are extremely diverse in form and function and the whole
spectrum of their diversity is commonly called biodiversity. Because individuals within a species display much
variability (genotypes and phenotypes) and ecosystems are made of individuals from up hundreds to thousands of species interacting together in space and time, the understanding of these interactions is extremely
complex. Biodiversity is not a static object of study, it is constantly evolving, the interactions with other elements of the system leading to an evolution towards different compositions and dynamics. The biodiversity
currently on Earth is a snapshot, the result of forces of evolution since the beginning of life, and it continues
to evolve, both qualitatively and quantitatively. In the context of current global environmental changes (climate
change, habitat destruction, biological invasions, pollutions), biodiversity is subject to new drivers of evolution and species must adapt or disappear. This provides scientists with novel challenges, turning a discipline
mostly based on attempts to understand patterns and processes to now trying to project and predict the future
of biodiversity, its functioning and the ecosystem functions and services it provides.
Speaker: Tzung-Su DING
School of Forestry and Resource Conservation, National Taiwan University
Bird Species Migration in East Asia, Australia and Surrounding Islands
Ecologists often fail to provide accurate and precise projection on consequences of ecological crisis caused
by human activities. This inability is mainly due to data availability, unclear causality and complexity of ecosystems, and adaptions of organisms. Here, using data of distribution range and contemporary environment, I
present a macroecological research on bird migration. We calculated the avian migration ratio (the proportion
of breeding species that migrate) in the lands from 70°E to 180°E and examined its relationships with the
annual ranges of ambient temperature, primary productivity (estimated by the Enhanced Vegetation Index),
and precipitation, along with island isolation and elevational range. The avian migration ratio increased with
increasing latitude in general but varied greatly between the two hemispheres. Additionally, it showed minimal
differences between continents and islands.
Our analyses reveal the seasonality of ambient temperature, which represents extra energy expenditure of
birds, is the dominant factor in determining bird species migration. Seasonality in primary productivity and
other environmental factors plays an indirect or limited role in bird species migration. Under current trends
of global warming, our findings should lead to further studies on the impacts of warming on bird migration.
27
Speaker: Jérôme MURIENNE
Evolution and Biological Diversity laboratory - CNRS - University Paul Sabatier - Toulouse
An evolutionary approach to environmental changes
One of the most critical challenge facing biologists is to understand and predict how environmental changes
will influence biodiversity. However, environmental changes have already affected biodiversity in the past and
there is much to learn from evolutionary studies. I will present recent advances in biogeography and how
paleontological information can be combined with DNA-based information to better understand the global
diversity of species in space and time. In the second part, I will present how such macroevolutionary studies
can be used to predict future extinction risks and adaptive potential of lineages or entire areas.
28
SESSION IV
SESSION FIELD
SOCIAL SCIENCES / HUMANITIES
SESSION TITLE
SOCIAL NETWORK: QUANTITATIVE ANALYSIS
MODELING AND ITS IMPACT
29
SESSION IV
SOCIAL SCIENCES / HUMANITIES
Social network: quantitative analysis, modeling and its impact
Speaker: Bertrand JOUVE
ERIC-IXXI – University of Lyon 2
Mathematical tools for social network modelling
I will present a brief overview of the mathematical tools that may be used to study social networks. The objective is to show that a wide range of methods may be relevant, from algebra to topology via statistic or combinatorics and graph theory. It will be illustrated by an example in the domain of history. That presentation will
open some questions about modelling in the Social and Human Sciences. It will be complementary to that of
David Chavalarias particularly focused on web and dynamical data and that of Zong-Rong Lee more sociology
driven with large surveys.
Speaker: David CHAVALARIAS
Centre d’Analyse et de Mathématiques Sociales & Institut des Systèmes Complexes de Paris Ile-de-France
Mining the online traces of the digital society: quantifying the evolution of topics in the
scientific literature, the press and the blogosphere
The exponential increase in the quantity and variety of textual information with which we are given to interact
paves the way toward new approaches to digital corpuses, leveraging quantitative analysis methods and
techniques of interactive visualization. The application of these approaches to different types of traces left by
the digital society (scientific archives, online news, blogs, etc.) along with the use of ad hoc tools, brings new
insights to understand the social dynamics and the dynamics of knowledge in a synthetic and multi-scale way.
Through different examples of reconstructions of these dynamics, we will show to what extent these traces
can be studied with quantitative approaches and we will ask the question of the predictability of the observed
patterns.
31
Speaker: Zong-Rong LEE
Academia Sinica
Social Network Analysis and Its Development in Taiwan
The purpose of this talk is to serve as a knowledge bridge between scholars in this conference, with the intention of fostering mutual understandings and possible collaborations among scholars constrained in their respective domains and geographic territories. For doing so, I will divide my talk into mainly three parts. Firstly, I
will briefly introduce some fundamental ideas and basic approaches of social network analysis utilized mostly
by sociologists and other social scientists. Secondly, I will introduce the history of social network analysis in
Taiwan and its recent developments and ongoing research projects. How Taiwanese scholars contributed to
the general knowledge of social network analysis with their various efforts and approaches will be broadly
sketched. And finally, I will illustrate with one peculiar research project about kinship networks of major
business elites in Taiwan. With a large scale of dataset assembled from records of elites obituaries published
across more than fifty years, this project was able to retrieve and analyze the structure of kinship networks
among local elite families. Additional datasets combined with directories of large business groups and political donation to election candidates enable this project to further gauge the extent to which the market and
political power landscape in Taiwan was influenced by such close-knit familial ties. I will present empirical
analyses showing the myriad impacts of kinship ties upon the economic exchanges, alliance activities and
political collective actions among business groups in Taiwan. The talk will conclude with thoughts on institutional understanding about how social networks emerge and function in this modern world.
32
CURRICULUM VITÆ
33
First Name Ebba
Last Name BRAKENHIELM
Position held Researcher
Laboratory Inserm U1096
Address Biomedical Research Institute Medical Faculty of Rouen University
22 Boulevard Gambetta, 76183 Rouen, France
Institution Inserm
Tel +33 2 35 14 83 70
Fax +33 2 35 14 83 65
E.mail ebba.brakenhielm@inserm.fr
URL http://www.insermu1096.fr/
Participant category General participant
Session field Life Sciences
Session title Ecology, biodiversity and evolution
Research Field Cardiovascular medicine, therapeutic angiogenesis, protein delivery,
biopolymers
Statement of your research interests
Spatiotemporally targeted growth factor protein therapy for creation of stable and functional blood vessels in
the heart as a new treatment option against chronic heart failure.
Recent most important publications
[1] Banquet S, Gomez E, Nicol L, Edwards F, Henry JP, Cao R, Schapman D, Dautreaux B, Lallemand F, Bauer
F, Cao Y, Thuillez C, Mulder P, Richard V, and Brakenhielm E Arteriogenic therapy by intramyocardial sustained
delivery of a novel growth factor combination prevents chronic heart failure. Circulation 2011 124:1059-1069
[2] Burton JB, Priceman SJ, Sung JL, Brakenhielm E, An DS, Pytowski B, Alitalo K, and Wu L Suppression of
Prostate Cancer Nodal and Systemic Metastasis by Blockade of the Lymphangiogenic Axis. Cancer Res 2008
68(19):7828-7837
[3] Nissen LJ, Cao R, Hedlund EM, Wang Z, Zhao X, Wetterskog D, Funa K, Brakenhielm E, and Cao Y Angiogenic
factors FGF2 and PDGF-BB synergistically promote murine tumor neovascularization and metastasis. J. Clin.
Invest. 2007 117(10):2766-2777
[4] Brakenhielm E, Burton JB, Johnson M, Charvarria N, Morizono K, Chen I, Alitalo K, and Wu L Modulating
metastasis by a lymphangiogenic switch in prostate cancer. Int J Can 2007 121(10):2153-2161
[5] Brakenhielm E, Cao R, Gao B, Angelin B, Cannon B, Parini P, and Cao Y Angiogenesis inhibitor, TNP-470,
prevents diet-induced and genetic obesity in mice. Circ Res. 2004 94(12):1579-1588
Poster Title Targeted dual growth factor delivery
Poster Abstract Therapeutic angiogenesis (creation of blood vessels) is a promising approach for the treat-
ment of cardiovascular diseases including myocardial infarction and chronic heart failure (CHF). However,
current strategies of therapeutic angiogenesis or arteriogenesis in cardiovascular diseases have proven insufficient. We aim to improve pro-angiogenic therapies by: i) identifying novel arteriogenic growth factor combinations; ii) developing injectable delivery systems for spatiotemporally-controlled growth factor release; and
iii) evaluating functional consequences of targeted, intramyocardial growth factor delivery in experimental
models of CHF.
35
First Name Maud
Last Name CHAMPAGNE-LAVAU
Laboratory Laboratoire Parole et Langage, UMR 7309
Address Laboratoire Parole et Langage, CNRS UMR 7309 Aix-Marseille
Université 5 Av. Pasteur B.P. 80975 13604 Aix-en-Provence, France
Institution CNRS
Tel +33 4 13 55 27 07
E.mail maud.champagne-lavau@univ-amu.fr
URL http://lpl-aix.fr/person/champagne-lavau
Session field Social Sciences / Humanities
Session title Social network: quantitative analysis, modeling and its impact
Research Field Neurolinguistics
My researches deal with pragmatic aspects of language such as non-literal language processing (indirect
request, irony). Non-literal language includes any linguistic construction producing an apparent need for the
listener to go beyond what is literally said to be able to grasp the speaker’s intention and can therefore understand the meaning of these statements in a given context. I work particularly on the relationship between
language and social cognition in pathology such as schizophrenia and right brain damaged people.
[1] Champagne-Lavau, M., Charest, A., Anselmo, K, Blouin, G. & Rodriguez, J.P. (2012). Theory of mind and
context processing in schizophrenia : the role of cognitive flexibility. Psychiatry Research, 200, 184-192.
[2] Champagne-Lavau, M., Fossard, M., Martel, G., Chapdelaine, C., Blouin, G., Rodriguez, J. P., et al. (2009).
Do patients with schizophrenia attribute mental states in a referential communication task ? Cognitive Neuropsychiatry, 14(3), 217-239.
Lecardeur, L., Stip, E., Giguere, M., Blouin, G., Rodriguez, J. P., &
3] Champagne-Lavau, M. (2009). Effects of cognitive remediation therapies on psychotic symptoms and cognitive complaints in patients with schizophrenia and related disorders: a randomized study. Schizophrenia
Research, 111(1-3), 153-158.
[4] Champagne-Lavau, M., & Joanette, Y. (2009). Pragmatics, Theory of mind and executive functions after a
right hemisphere lesion: Different patterns of deficits. Journal of Neurolinguistics, 22, 413-426.
[5] Monetta, L. & Champagne-Lavau, M. (2009). Right hemisphere damage and pragmatics. In L. Cummings
(Ed.). Pragmatics Encyclopedia, 1st edition, pp. 438-440. Routledge.
36
Poster Title Assessing theory of mind during social interaction in schizophrenia
Poster Abstract Many studies have reported that patients with schizophrenia (SZ) may have impaired social
cognition, resulting in communication disorders and theory of mind impairments. Theory of mind (ToM) refers
to the ability to form representations of other people’s mental states (e.g. intention, thought, belief, knowledge)
and to use these representations to understand, predict and judge their behaviors and statements. Most of the
classical tasks used to assess impaired ToM ability are too complex, and McCabe et al. (2004) suggested that
in real life conversations SZ patients were able to attribute mental states to achieve successful communication. The aim of this study was to assess ToM ability in schizophrenia using both a classical task and a referential communication task. The referential communication paradigm enables one to assess how interlocutors
conversing about how to arrange a set of pictures take into account or not shared knowledge. The main
results showed that SZ patients had difficulties using reference markers and attributing mental states in both
ToM tasks. Contrary to healthy participants, they exhibited a tendency to ineffectively mark the information
they used (indefinite articles for old information and/or definite articles for new information) and had problems
using information they shared with the experimenter.
37
First Name David
Last Name CHAVALARIAS
Laboratory Institut des systèmes complexes de Paris Ile-de-France Centre d’analyse et de mathématiques sociales
Address 57-59 rue Lhomond 75005 Paris
Institution CNRS
Tel +33 1 42 17 40 32
E.mail david.chavalarias@ehess.fr
URL http://chavalarias.com
Participant category Speaker
Session field Social Sciences/Humanities
Session title Social network : quantitative analysis, modelling and its impact
Research Field Socio-semantic networks, cultural evolution modeling, information
visualization, quantitative epistemology, complex systems modeling
David Chavalarias studies the social and cognitive dynamics, both from the modeling and data-mining point
of view. His research is strongly interdisciplinary and includes: quantitative epistemology, information visualization, modeling of the cultural dynamics, socio-semantic networks modeling, scientific discovery processes
and cognitive economics. He has been involved in the design of several interfaces for mapping knowledge
dynamics from large corpora: academic digital repositories, online media or press.
David Chavalarias is the director of the Complex Systems Institute of Paris Ile-de-France
(ISC-PIF - http://iscpif.fr) and Vice-President of the Complex Systems Society (http://cssociety.org).
[1] Chavalarias D. and Cointet J-P. (2013) Phylomemetic Patterns in Science Evolution - The Rise and Fall of
Scientific Fields, PLoS One.
[2] Chavalarias (2012) La société (re)commandée, De la conjecture de von Foerster aux sciences sociales
prédictives, in Conflits des interprétations dans la société de l’information : éthique et politique de l’environnement (Traité des sciences et techniques de l’information), CHARDEL Pierre-Antoine, GOSSART Cédric, REBER
Bernard Eds, Lavoisier.
[3] Chavalarias & Ioannidis (2010) Science mapping analysis characterizes 235 biases in biomedical research,
Journal of Clinical Epidemiology, Volume 63, Issue 11, November 2010, Pages 1205-1215
[4] Chavalarias D. & Cointet J-P (2008) Bottom-up scientific field detection for dynamical and hierarchical
science mapping - methodology and case study Scientometrics Vol. 75 No. 1, 37-50 , (DOI): 10.1007/s11192007-1825-6.e-print
[5] Bourgine P., Chavalarias D. and Cohen-Boulakia C. (Eds.) Déterminismes et Complexités : Du Physique à
l’Ethique - autour d’Henri Atlan, (2008) Ed. La Découverte.
38
First Name Hsuan-Yi
Last Name CHEN
Position held Professor
Address Department of Physics, National Central University, Jhongli,
32001 Taiwan
Institution National Central University
Tel +886 3 4227-151 ext65367
Fax +886 3 4251-175
E.mail hschen@phy.ncu.edu.tw
URL http://www.phy.ncu.edu.tw/ softbio_…
Participant category PGM
Session field Physical Sciences
Session title Arrow of time and nonequilibrium thermodynamics
Research Field Bio/soft-matter theory
Theoretical modeling of active particles, biomembranes, subcellular processes.
[1] Coarse-grain simulations of active molecular machines in lipid bilayers, Mu-Jie Huang, Raymond Kapral,
Alexander S. Mikhailov and Hsuan-Yi Chen, Journal of Chemical Physics, 138, 195101 (2013).
[2] Trajectories of Listeria-type motility in two dimensions, Fu-Lai Wen, Kwan-tai Leung, and Hsuan-Yi Chen,
Phys. Rev. E 86, 061902 (2012).
[3] Strength of adhesion clusters under shared linear loading, Hsin-Hui Liang and Hsuan-Yi Chen, Phys. Rev.
E, 83, 061914 (2011).
[4] Dynamics of biomembranes with active multiple-state inclusions, Hsuan-Yi Chen and A.S. Mikhailov, Phys.
Rev. E, 81, 031901 (2010).
[5] Bell’s expression and generalized Garg’s form for forced dissociation of a biomolecular complex, Han-Jou
Lin, Hsuan-Yi Chen, Yu-Jane Sheng, and Heng-Kwong Tsao, Phys. Rev. Lett., 98, 088304 (2007).
Poster Title Symmetry breaking bacteria motion
Poster Abstract I will introduce models for two distinct types of bacteria movement, the actin-based motility
of Listeria monocytogenes and the gliding motion of Flavobacterium johnsoniae. The physical mechanism for
these two different bacteria are very different but bifurcations that break the symmetries are essential in both
systems.
A Listeria bacterium moves in the host cell by hijacking the actin polymerization machinary with its special
surface protein. The motion of Listeria in a quasi two-dimensional environment shows geometrical trajectories
ranging from straight lines, circles, S-shape curves, figure eights, etc. With a simple Landau-type model I will
show that these trajectories are results of bifurcations in the distribution of actin filaments and force density
on the Listeria surface.
A Flavobacterium johnsoniae moves on a substrate by processive adhesive proteins which are distributed in a
close-loop track. Even in a homogeneous medium, the bacterium breaks the front-rear symmetry and shows
directional movement. I will show that at sufficiently high adhesive protein speed, the distribution of closed
bonds between the proteins and the substrate has a bifurcation that leads to a directional movement for the
bacterium. Such mechanism has the advantage that the bacterium can tune the adhesive protein speed to
detect small gradient of nutrient or toxin in the environment.
39
First Name Kate Huihsuan
Last Name CHEN
Position held Associate Professor
Laboratory Seismology
Address No.88, Sec. 4, Tingzhou Rd., Wenshan District, Taipei 11677
Institution National Taiwan Normal Univ.
Tel +886-9-8825-0062
E.mail katepili@ntnu.edu.tw
URL http://katepili.wix.com/kate-chen
Participant category Chair
Session field Applied Sciences
Session title Disaster prevention/Prediction
Research field Observational seismology
My research is primarily focused on earthquake seismology, mainly the physics of seismological phenomena
associated with different styles and mechanisms of slip in natural fault systems.
[1] Chen, K. H., Nadeau, R. M., and Rau, R. J. (2007). Towards a universal rule on the recurrence interval scaling of repeating earthquakes?,Geophys. Res. Lett., 34, L16308, doi:10.1029/2007GL030554. chosen as AGU
journal editors’ highlight
[2] Chen, K. H., Nadeau, R. M., and Rau, R. J. (2008). Characteristic repeating microearthquakes on an arc-continent collision boundary - the Chihshang fault of eastern Taiwan, Earth Planet. Sci. Lett., 276, doi:10.1016/j.
epsl.2008.09.021.
[3] Chen, K. H., Bürgmann, R., Nadeau, R. M., T. Chen, N. Lapusta (2010), Postseismic variations in seismic moment and recurrence interval of repeating earthquakes, Earth Planet. Sci. Lett., 299, 118-125, doi: 10.1016/j.
epsl.2010.08.027.
[4] Chen, K. H., Furumura, T., Rubinstein, J., and Rau, R. J. (2011), Observations of changes in waveform character
induced by the 1999 Mw7.6 Chi-Chi earthquake, Geophys. Res. Lett., 38, L23302, doi:10.1029/2011GL049841.
[5] Chen, K. H., Burgmann, R., Nadeau, R. M. (2013), Do earthquakes talk to each other? Triggering and interaction of repeating sequences at Parkfield, J. Geophys. Res., 118, 165-182, doi:10.1029/2012JB009486.
40
Poster Title Do earthquakes talk to each other?
Poster Abstract Knowledge of what governs the timing of earthquakes is essential to understanding the
nature of their cycles and to determining earthquake hazard, yet the variability and controls of earthquake
recurrences are not well established. Repeating earthquakes have been well established in several tectonic
settings like Japan subduction zone, Parkfield, and Taiwan. We found that there seems to exist a universal rule
on recurrence interval scaling of repeating earthquakes in diverse tectonic settings. That is, tectonic loading
rate is the most important factor that controls the repeat time. What governs the timing of repeating earthquakes, however, is still an open question. We do not know how the repeating sequences respond to static
stress perturbations associated with nearby earthquakes, and to what degree fault interaction influences
the timing of repeating earthquakes. The large population of small, characteristically repeating earthquakes
at Parkfield provides a unique opportunity to study how the interaction of nearby earthquakes affects their
recurrence properties. We analyze 112 M -0.4 3.0 repeating earthquake sequences (RESs) to examine the
triggering effect from nearby microseismicity. We find that the repeating events with a smaller number of
neighboring earthquakes in their immediate vicinity tend to recur in a more periodic manner. The total stress
perturbation from close-by earthquakes, however, does not seem to impact RES regularity and timing much.
Instead, close-by-events influence RES timing in a matter of minutes or hours by short-term triggering. Events
that occurred within less than 1 day of an RES often imposed or experienced high stress changes. A static
stress increment of 30 kPa is enough, to produce such effectively immediate triggering. This requires that the
triggered repeating events are already near the end of their earthquake cycle.
41
First Name Chun-Fang
Last Name CHIANG
Position held Assistant Professor
Laboratory
Address Dept. Economics, NTU 21, Hsu-Chow Road,
Taipei 100, Taiwan
Institution National Taiwan University
Tel + 886 2-2351-9641ext457
E.mail chunfang@ntu.edu.tw
URL homepage.ntu.edu.tw/ chunfang/
Research Field Political Economy, Labor Economics
My research focuses on the interactions between economics and politics. In the media markets, I investigate
how market structure would affect political ideologies of media outlets, and how media outlets influence
voters’ decisions. I am also interested in the economic factors of individuals’ political attitudes under globalization. Using data from Taiwan, I found that national identity in Taiwan has been influenced by the economic
interactions between China and Taiwan.
[1] “Media Bias and Its Influence : Evidence from Newspaper Endorsements”, with Brian Knight*, July 2011,
Review of Economic Studies, 78(3), 795-820
[2] “Individual Preferences towards Trade Partners in Taiwan” with Jin-Tan Liu, and Tsia-Wei Wen, March
2013, Economics & Politics, 25, 91–109.
42
First Name Yen-Sheng
Last Name CHIANG
Address No. 128, Sec. 2, Academia Rd., Nankgang, Taipei, Taiwan 11529
Employer Academia Sinica
Tel +886-2-2652-5107
Fax +886-2-2652-5050
E.mail chiangys@gate.sinica.edu.tw
Research Field Social networks, computational modeling, social psychology, group behavior
I am interested in how pro-social behavior, such as cooperation, fairness and trust emerges in human behavior. I am also interested in how decisions are made at the collective level through networks. I use computer
simulation to derive theoretical findings and then run experiments with human subjects to test them.
[1] 2013 “Cooperation could evolve in complex networks when activated conditionally on network characteristics.” Journal of Artificial Societies and Social Simulation, 16: 6.
[2] 2013 “Book review on ‘Complex Adaptive System’ by Miller and Page.” Journal of Mathematical Sociology,
37 : 59-60.
[3] 2011 “Judgment of Distributional Inequality in Networks.” Social Networks 33 : 342-349
[4] 2011 “Network Homophily and the Evolution of the Pay-it-Forward Reciprocity.” (with Nobuyuki Takahashi)
PLoS ONE 6 : e29188.
[5] 2010 “Self-Interested Partner Selection can Lead to the Emergence of Fairness.” Evolution and Human
Behavior 31 : 265-270.
Poster Title Cooperation and Sociality
43
First Name Yung-Hao
Last Name CHING
Position held Assistant professor
Address No.701, Sec. 3, Zhongyang Rd., Hualien City, Hualien County 970,
Taiwan (R.O.C.)
Institution Tzu-Chi University
Tel +886 3-856-5301 Office ext 2693 Lab ext 2695
Fax +886 3-857-8386
E.mail yching@mail.tcu.edu.tw
URL www.tcu.edu.tw
Research Field Genetics
My general research interests are molecular genetics and functional genomics in mammalian development.
I am interested in using mouse as model to study human disease that can contribute to the understanding
the molecular control of organogenesis
[1] Mutation in myosin heavy chain 6 causes atrial septal defect. Ching YH, Ghosh TK, Cross SJ, Packham EA,
Honeyman L, Loughna S, Robinson TE, Dearlove AM, Ribas G, Bonser AJ, Thomas NR, Scotter AJ, Caves LS, Tyrrell
GP, Newbury-Ecob RA, Munnich A, Bonnet D, Brook JD. Nat Genet. 2005 Apr;37(4):423-8. Epub 2005 Feb 27.
[2] Random mutagenesis of proximal mouse chromosome 5 uncovers predominantly embryonic lethal mutations. Wilson L, Ching YH, Farias M, Hartford SA, Howell G, Shao H, Bucan M, Schimenti JC. Genome Res. 2005
Aug;15(8):1095-105. Epub 2005 Jul 15.
[3] An allele separating skeletal patterning and spermatogonial renewal functions of PLZF. Ching YH, Wilson LA,
Schimenti JC. BMC Dev Biol. 2010 Mar 25;10(1):33.
[4] High resolution mapping and cloning of ENU-induced mutations in the Rw region of mouse Chromosome
5. Ching YH, Munroe RJ, Moran JL, Barker AK, Mauceli E, Fennell T, Dipalma F, Lindblad-Toh K, Abcunas LM,
Gilmour JF, Harris TP, Kloet SL, Luo Y, McElwee JL, Mu W, Park HK, Rogal DL, Schimenti KJ, Shen L, Shindo
M, Shou JY, Stenson EK, Stover PJ, Schimenti JC. BMC Genet. 2010 Nov 30;11(1):106. [Epub ahead of print]
[5] Transcriptomes of mouse olfactory epithelium reveal sexual differences in odorant detection. Shiao MS, Chang
AY, Liao BY, Ching YH, Lu MY, Chen SM, Li WH. Genomics Research Center, Academia Sinica, Taipei, Taiwan, ROC.
Poster Title Mutations Causing Embryonic Lethality in Mouse: A Functional Genomic Approach
Poster Abstract Forward genetic screens in mice provide an unbiased approach to functionally identify gene
and other genetic elements. A large-scale three-generation ENU mutagenesis program was conducted by my
previous laboratory to fine dissect the function of a 50 Mb region of the mouse chromosome 5. Out off 1000
mutant pedigrees tested, a totally of 37 recessive lethal families were identified, the biggest phenotype class
recovered. We have cloned and characterized these 37 families and reported 13 alleles that are responsible for
the phenotype of these lethal families: eight genes with no previously reported mutant models and five mutations in genes previously reported. According to our data, the mouse genome estimated to have 3479 embryonic lethal genes. The estimated active protein-coding mouse genes are roughly consistent with human genes,
and the high percentage of embryonic lethal genes in mice may reflect an complex process of development.
44
First Name James
Last Name CHU
Laboratory Department of Civil Engineering
Address No.300, Jhongda Rd., Jhongli, Taoyuan, 320, Taiwan
Tel +886-3-422-7151#34151
Fax +886-3-425-2960
E.mail jameschu@ncu.edu.tw
URL http://www.ncu.edu.tw/ jameschu
Session title Disaster prevention/prediction
Research Field Civil engineering
I am interested in
(1) pedestrian simulation and hazard mitigation for transportation facilities,
(2) transportation planning, and
(3) transportation infrastructure life-cycle management.
[1] Chu, J. C.* (2013), Condition-Dependent Maintenance Effectiveness in Dynamic Performance Models for
Transportation Infrastructure, ASCE Journal of Infrastructure Systems, 19(1), 85-98.
[2] Chu, J. C.* and Chen, Y.-J. (2012), Optimal Threshold-based Network-level Transportation Infrastructure
Life-cycle Management with Heterogeneous Maintenance Actions, Transportation Research Part B, 46(9),
1123-1143.
[3] Chu, J. C.* and Yeh, C.-Y. (2012), Emergency Evacuation Guidance Design for Complex Building Geometries,
ASCE Journal of Infrastructure Systems, 18(4), 288-296.
[4] Chu, C.-Y.* (2009), A Computer Model for Selecting Facility Evacuation Design Using Cellular Automata,
Computer-Aided Civil and Infrastructure Engineering, 24(8), 608-622.
[5] Chu, C.-Y. and Durango-Cohen, P.* (2008), Estimation of Dynamic Performance Models for Transportation
Infrastructure using Panel Data, Transportation Research Part B, 42(1), 57-81.
Poster Title Emergency Evacuation Guidance Design and Evaluation for Complex Building
Geometries
Poster Abstract The planning for pedestrian evacuation in large public-gathering buildings is important be-
cause pedestrians are vulnerable to various types of emergency events. One of the most critical measures of
the preparedness of a building during these events is its evacuation guidance. This paper proposes a method
for designing evacuation guidance systems in complex building spaces by solving a maximum coverage problem with side constraints of number of signs and evacuation routes. An example based on a transportation
terminal is presented to validate the methodology. The results show that the proposed methodology is effective and can be used for supporting emergency evacuation planning for buildings.
45
Name Kuo-Fang
Last Name CHUNG
Laboratory Plant Evolution and Biogeography
Address School of Forestry and Resource Conservation National Taiwan
University No. 1, Sec. 4, Roosevelt Road, Taipei, 10617 Taiwan
Tel +886-2-3366-4643
Fax +886-2-2365-4520
E.mail kuofangchung@ntu.edu.tw
URL http://www.fo.ntu.edu.tw/people/bio…
Research Field Plant Evolution
I am a plant taxonomist. I am interested in understanding the history and mechanisms underlying the amazing biodiversity. To understand these, we use molecular tools to generate the evolutionary relationships and
quantify the extent of genetic diversity. Current projects in my lab include the evolution and taxonomy of Asian
Begonia, speciation of limestone plants, biogeography of barberries, population structure of alpine plants,
conservation genetics of Taiwan Sassafras, and the dispersa of paper mulberry.
[1] CHUNG, K.-F., H.-Y. HUANG, C.-I PENG, AND W.-B. XU. Primulina mabaensis (Didymocarpeae, Cyrtandroideae, Gesneriaceae): a new species from a limestone cave of northern Guangdong, China. Phytotaxa 92 : 4048. KONO, Y., K.-F. CHUNG, C.-H. CHEN, Y. HOSHI, H. SETOGUCHI, C.-H. CHOU, K. OGINUMA, et al. 2012.
[2] Intraspecific karyotypic polymorphism is highly concordant with allozyme variation in Lysimachia mauritiana (Primulaceae : Myrsinoideae) in Taiwan : implications for the colonization history and dispersal patterns
of coastal plants. Annals of Botany 110 : 1119-1135. XU, W.-B., Q. ZHANG, F. WEN, W.-B. LIAO, B. PAN, H.
CHANG, and K.-F. CHUNG. 2012.
[3] Nine new combinations and one new name of Primulina (Gesneriaceae) from South China. Phytotaxa 64 :
1-8. CHUNG, K.-F. T.-T. LIN, Y.-S. TSAI, S.-T. LIN, AND C.-I PENG. 2011.
[4] Isolation and characterization of microsatellite loci in Sassafras randaiense (Lauraceae). American Journal
of Botany 98 : e326–e329. CHUNG, K.-F., H. VAN DER WERFF, AND C.-I PENG. 2010.
[5] Observations on the floral morphology of Sassafras randaiense (Lauraceae). Annals of the Missouri Botanical Garden 97 : 1–10.
46
Poster Title Evolution on Guangxi’s limestone karsts—Phylogenetics of Primulina
Poster Abstract The picturesque karst landscapes of Guangxi, China, featured by spectacular limestone
towers and caves, have been hypothesized to have played crucial roles in generating high biodiversity and
endemism there. To test this hypothesis, evolutionary relationships of Primulina, an exemplar of Guangxi’s
limestone flora confined to various limestone habitats, were reconstructed using DNA sequence data. Phylogenetic relationships reveal that species distributed in geographical proximity are also phylogenetically closely
related, suggesting that species diversification were driven mainly through geographic isolation. Divergent
time estimates indicate that Primulina originated at ca. 23 million years before present (MYBP) and the basal
Primulina clades derived from within a narrow time-span ranging from 19.53 to 18.37 MYBP, all within the
Miocene. The inferred tempo and mode of speciation suggests that rapid accumulation of extant Primulina
species is highly correlated with the formation of Guangxi’s modern limestone karsts. During the Miocene, the
uplift of Tibet Plateau to sufficient height greatly altered the pattern of East Asian monsoon, most importantly
increasing the rainfall in Guangxi and accelerating the weathering of carbonate substrate and facilitating the
formation of the karst landscape (karstification). Meanwhile, the karstification also intensified the isolation of
Primulina populations, facilitating population diversification and eventually leading to speciation.
47
First Name Sylvain
Last Name CLAIR
Laboratory IM2NP
Address Aix-Marseille University, campus de Saint Jerome,
Avenue N. Niemen 13397 Marseille cedex 20 France
Institution CNRS
Tel +33 4 91 28 85 38
E.mail sylvain.clair@im2np.fr
URL http://www.im2np.fr/recherche/nano/
Session title Arrow of time and non-equilibrium thermodynamics
Research Field Nanoscience, scanning tunneling microscopy, surface self-assembly, 2D polymers
My research interest is on the elaboration and characterization of self-assembled molecular nanostructures
on surfaces and in particular on the formation of a new class of materials: two-dimensional polymers. I am
developing new approaches to control the activation of a chemical reaction and to create original systems with
programmed structure and functionality.
[1] Single layer of polymeric Fe-phthalocyanine : a fully conjugated organometallic sheet M. Abel, S. Clair, O.
Ourdjini, M. Mossoyan, L. Porte, Journal of the American Chemical Society 133,1203 (2011)
[2] Tip- and electron beam-induced surface polymerization S. Clair, O. Ourdjini, M. Abel, L. Porte, Chemical
Communications (2011) ˇ
[3] Coverage-dependent formation of chiral ethylhiolate-Au-complexes on Au(111) S. Clair, Y. Kim, M. Kawai,
Langmuir 27, 627 (2011)
[4] Mesoscopic arrays from supramolecular self-assembly S. Clair, M. Abel, L. Porte, Angewandte Chemie
International Edition 49, 8237 (2010)
[5] Substrate-induced arrays of quantum dots in a single-walled carbon nanotube H.-J. Shin, S. Clair, Y. Kim,
M. Kawai, Nature Nanotechnology 4, 567 (2009)
Poster Title Growth of two-dimensional polymers
Poster Abstract Supramolecular self-assembly at surfaces has proven in the last two decades to be very
efficient for creating atomically-controlled organic nanostructures. The possibility of extending the concepts of
supramolecular chemistry to the formation of covalent bonds between molecular tectons has attracted recent
focus, and the demonstrations of covalent polymerization performed directly at surfaces have opened promising perspectives. However, the formation mechanism is here very complex due to the necessary activation of
a chemical reaction. In addition, the irreversible character of a covalent bond usually precludes the formation
of the thermodynamically most stable structure through defect self-healing. Nevertheless, exquisite details on
the complex mechanisms involved in the growth of two-dimensional polymers can be gained by comparing
different systems based on various chemical functions.
48
First Name Franck
Last Name COURCHAMP
Position held Senior Researcher
Laboratory ESE - UMR CNRS 8079
Address Labo Ecologie, Systématique & Evolution UMR CNRS 8079
Bat 362 Université Paris Sud 91405 Orsay Cedex
Institution CNRS
Tel +33 1 69 15 56 85
Fax +33 1 69 15 56 96
E.mail franck.courchamp@u-psud.fr
URL http://max2.ese.u-psud.fr/epc/conse
Session title Ecology, Biodiversity and evolution
Research Field Ecology
I work on population dynamics in the framework of conservation biology. Basically, I’m interested in trying to
understand the causes and mechanisms of population decline and extinctions. My topics range from biological
invasions to overexploitation and climate change. Focussing on processes rather than specific species, I use a
large number of animal models, with a combination of experimental work, both in the lab and in the field, and
analytic and theoretical studies.
[1] Duan Biggs, Franck Courchamp, Rowan Martin, Hugh P. Possingham. 2013. Legal Trade of Africa’s Rhino
Horns. Science. 339 : 1038-1039.
[2] Simberloff D., J-L Martin, P Genovesi, V Maris, D A Wardle, J Aronson, F Courchamp, B Galil, E GarcíaBerthou, M Pascal, P Pyšek, R Sousa, E Tabacchi & M Vilà. 2013. Impacts of biological invasions - what’s what
and the way forward. Trends in Ecology and Evolution. 28 : 58–66.
[3] Cleo Bertelsmeier, Gloria M. Luque & Franck Courchamp. 2013. More and better : two ways to increase
invasive range under climate change. Conservation Biology. In press.
[4] Bellard, C., Bertelsmeier, C., Leadley, P., Thuiller, W. and Courchamp, F. 2012. Impacts of climate change on
the future of biodiversity. Ecology Letters. 15/4 : 365–377.
[5] Franck Courchamp, Joanna Gascogne & Ludek Berek. 2008. Allee effects in ecology and conservation.
Oxford University Press. 264 p.
49
First Name Tzung-Su
Last Name DING
Laboratory School of Forestry and Resource Conservation
Address No. 1 Sec. 4 Roosevelt Rd Taipei, 10611 Taiwan
Tel +886-2-3366-5263
E.mail ding@ntu.edu.tw
Research Field Life Sciences
Community ecology, wildlife and forest habitats, macro-ecology, ornithology, landscape ecology, biogeography, Geographic Information System, wildlife conservation.
[1] Ko, C.-Y., R.-S. Lin, T.-S. Ding, C.-H. Hsieh, and P.-F. Lee. 2009. Identifying biodiversity hotspots by predictive
models: a case study using Taiwan’s endemic bird species. Zoological Studies 48(3):418-431.
[2] Ding, T.-S., H.-C. Liao, H.-W. Yuan. 2008. Breeding bird community composition in different successional
vegetation in the montane coniferous forests zone of Taiwan. Forest Ecology and Management 255(7): 20382048.
[3] Chang, Y.-M., K.A. Hatch, T.-S. Ding*, D. Eggett, H.-W. Yuan, B.L. Roeder. 2008. Using stable isotopes to
unravel and predict the origins of Great Cormorants (Phalacrocorax carbo sinensis) overwintering at Kinmen.
Rapid Communications in Mass Spectrometry 22: 1235-1244.
[4] Ding, T.-S., S. Geng, P.-F. Lee, and H.-W. Yuan. 2006. Primary productivity and isolation as the major determinants of bird species richness in East Asia. Journal of Biogeography 33(4): 683-693.
[5] Ding, T.-S., H.-W. Yuan, S. Geng, Y.-S. Lin, and P.-F. Lee. 2005. Energy flux, body size, and density in relation to bird species richness along an elevational gradient in Taiwan. Global Ecology and Biogeography 14(4):
299-306.
50
First Name Fabienne
Last Name GAUFFRE
Position held Researcher/Assistant
Laboratory Institut des Sciences Chimiques de Rennes
Address Campus Beaulieu, Bat 10 A Rennes
Institution CNRS
Tel +33 2 23 23 63 98
Fax +33 2 23 23 66 31
E.mail fabienne.gauffre@univ-rennes1.fr
URL http://blogperso.univ-rennes1.fr/fa…
Research Field Physical-chemistry; nano-chemistry
My current research interests are focused on two main topics:
nano-particles interfaces and hybrids assemblies of nanoparticles and polymers. Adsorption at nanoparticle
surfaces and nanoparticle toxicology.
block copolymers containing a DNA block, their assemblies into polymer nanoparticles and use in sensor
devices.
[1] G. Fuks, L. Kaps, J. Oberdisse, C.Cerclier, C.Gaillard, C.Mingotaud, F. GauffreDNA–Polymer Micelles as
Nanoparticles with Recognition Ability, Chemistry, 2012, 48, pages 13495–13501
[2] A. Dazazzi, Y. Coppel, M. In, C. Chassenieux, P. Mascalchi, L. Salomé, A. Bouhaouss, M. Kahn, F. Gauffre Oligomeric and Polymeric Surfactants for the Transfer of Luminescent ZnO Nanocrystals to Water, J. Mater Chem
C, 2013,1, 2158-2165
[3] J. Rubio Garcia, A. Dazzazi, Y. Coppel, P. Mascalchi, L. Salomé, A. Bouhaouss, M. L. Kahn, F. Gauffre Transfer
of hydrophobic ZnO nanocrystals to water : an investigation of the transfer mechanism and luminescent properties J. Mater. Chem. 2012, 22 (29), 14538 - 14545
[4] J. Rubio-Garcia,Y. Coppel, P. Lecante, C. Mingotaud, B. Chaudret, F. Gauffre, M. L. Kahn One-step synthesis
of metal and metal oxide nanoparticles using amino-PEG oligomers as multi-purposes ligands : size and shape
control, and quasi-universal solvent dispersability Chem. Commun., 2011, 47 (3), p.988 – 990
[5] K.Rahme, P. Vicendo, C. Ayela, C. Gaillard, B. Payré, C. Mingotaud, F. Gauffre A Simple Protocol to Stabilize
Gold Nanoparticles using Amphiphilic Block-Copolymers : Stability Studies and Viable Cellular Uptake. Chemistry, a European Journal, 2009, 15, 42, p.11151-11159
51
First Name Charlie
Last Name GOSSE
Laboratory LPN
Address Route de Nozay 91460 Marcoussis
Institution CNRS
Tel +33 1 69 63 6155
Fax +33 1 69 63 60 06
E.mail charlie.gosse@lpn.cnrs.fr
URL http://www.lpn.cnrs.fr
Research Field Biophysical chemistry
Spatiotemporal dynamics of chemical reaction networks, Microsystem engineering, Molecular interactions,
Kinetics
[1] C. Hoffmann, E. Mazari, S. Lallet-Millet, R. Le Borgne, V. Marchi, C. Gosse, and Z. Gueroui. Spatiotemporal
control of microtubule nucleation and growth triggered by magnetic nanoparticle assembly. Nature Nanotech.
8 (2013) 199-205.
[2] E. Mazari, X. Zhao, J. Collignon, A. Perea-Gomez, and C. Gosse. On chip spatiotemporal electric field shaping
to locally electroporate cell markers into mouse embryonic tissues. MicroTAS 2012, Proceedings of the 16th
International Conference on Miniaturized Systems for Chemistry and Life Sciences, pp. 1729-1731.
3] A. Fang, C. Gosse, C. Gaillard, X. Zhao, and J. Davy. Tuning silica particle shape at fluid interfaces. Lab Chip
12 (2012) 4960-4963.
[4] C. Hamon, M. Postic, E. Mazari, T. Bizien, C. Dupuis, P. Even-Hernandez, A. Jimenez, L. Courbin, C. Gosse,
F. Artzner, and V. Marchi-Artzner. Three-dimensional self-assembling of gold nanorods with controlled macroscopic shape and local smectic B order. ACS Nano 6 (2012) 4137-4146.
[5] K. Zrelli, T. Barilero, E. Cavatore, H. Berthoumieux, T. Le Saux, V. Croquette, A. Lemarchand, C. Gosse, and
L. Jullien. Temperature modulation and quadrature detection for selective titration of two-state exchanging
reactants. Anal. Chem. 83 (2011) 2476-2484.
52
First Name Pai-Yi
Last Name HSIAO
Laboratory Department of Engineering and System Science
Address 101, Sec. 2, Kuang-Fu Rd., Hsinchu, Taiwan 30013
Institution National Tsing Hua University
Tel +886-3-5162-247
E.mail pyhsiao@ess.nthu.edu.tw
URL http://mx.nthu.edu.tw/ pyhsiao/
Research Field Soft matter physics
My research concerns several different topics in the domain of soft condensed matter, including electrokinetics and conformational study of charged macromolecules in solutions, properties of polyelectrolyte brush
in electric fields, elasticity of lipid membranes, adhesion between proteins and surfaces, heat transport on
molecular wires, etc. The goal is to seek a fundamental understanding of these systems through computer
simulations.
[1] Ho YF, Shendruk TN, Slater GW, Hsiao PY*, “Structure of Polyelectrolyte Brushes Subject to Normal Electric
Fields”, Langmuir 29, pp. 2359-2370 (2013)
[2] Wu KM, Wei YF, Hsiao PY*, “Polyelectrolytes in Multivalent Salt Solutions under the Action of DC Electric
Fields”, Electrophoresis 32, pp. 3348-3363 (2011)
[3] Huang CH, Hsiao PY*, Tseng FG, Fan SK, Fu CC, Pan RL, “Pore-Spanning Lipid Membrane under Indentation
by a Probe Tip : A Molecular Dynamics Simulation Study”, Langmuir 27, pp. 11930-11942 (2011)
[4] Hsiao PY*, Wei YF, Chang HC, “Unfolding Collapsed Polyelectrolytes in Alternating-Current Electric Fields”,
Soft Matter 7, pp. 1207-1213 (2011)
[5] Hung SW, Hsiao PY, Chieng CC*, “Dynamic Information for Cardiotoxin Protein Desorption from a MethylTerminated Self-Assembled Monolayer Using Steered Molecular Dynamics Simulation”, J. Chem. Phys. 134,
194705 (2011)
53
First Name Hong-Ren
Last Name JIANG
Laboratory Institute of Applied Mechanics
Address No.1, Sec. 4, Roosevelt Rd., Da’an Dist., Taipei City 106,
Taiwan (R.O.C.)
Tel + 886-9-8983-2072
E.mail hrjiang@iam.ntu.edu.tw
URL http://www.iam.ntu.edu.tw/iam/profe… Jiang
Research Field Physics, soft matter
Soft matter, Biophysics, Nonequilibrium transport, Active matter, Optical manipulation
[1] Hong-Ren Jiang, Natsuhiko Yoshinaga, Masaki Sano, Active Motion of Janus Particle by Self-thermophoresis in Defocused Laser Beam,Phys. Rev. Lett., Vol. 105, 268302 (2010).
[2] Hong-Ren Jiang, Hirofumi Wada, Natsuhiko Yoshinaga, and Masaki Sano Manipulation of Colloids by Nonequilibrium Depletion Force in a Temperature Gradient ,Phys. Rev. Lett 102, 208301 (2009).
[3] Hong-Ren Jiang and Masaki Sano Stretching Single Molecular DNA by Temperature Gradient, Appl. Phys.
Lett. 91, 154104 (2007).
[4] Shoichi Toyabe, Hong-Ren Jiang, Takenobu Nakamura, Yoshihiro Murayama, and Masaki Sano Experimental Test of a New Equality: Measuring Heat Dissipation in an Optically Driven Colloidal System , Phys. Rev. E 75,
011122 (2007)Appl. Phys. Lett. 91, 154104 (2007).
54
First Name Bertrand
Last Name JOUVE
Laboratory ERIC - IXXI
Address Lyon 2 University - France
Institution MESR
Tel +33 6 71 57 67 78
Fax
E.mail bertrand.jouve@univ-lyon2.fr
URL http://eric.univ-lyon2.fr/ bjouve/B…
Research Field Graph theory Social Network analysis
I focus on how the representation and mathematical modeling of real data as a network can improve our
knowledge of these data. In the context of graph theory, I develop mathematical tools from data analysis,
spectral analysis or topology. I have studied real neural networks, social networks and networks of landscape
fragmentation (parcels).
I am particularly involved in cooperation with human and social sciences (director of The Toulouse Social
Sciences and Humanities Research Institute during 6 years and currently deputy director at the Institute for
Humanities and Social Sciences - CNRS)
[1] Villa-Vialaneix N., Jouve B., Rossi F., Hautefeuille F. (2012) Spatial correlation in bipartite networks : the impact of the geographical distances on the relations in a corpus of medieval transactions. Revue des Nouvelles
Technologies de l’Information (SHS-1) : 97-110
[2] Boulet R, Fieux E, Jouve B (2010) Simplicial simple-homotopy of flag complexes in terms of graphs. European Journal of Combinatorics 31: 161-176.
[3] Culus JF, Jouve B (2009) Convex circuit free coloration of an oriented graph. European Journal of Combinatorics 30(1): 43-52.
[4] Boulet R, Jouve B (2008) The lollipop graph is determined by its spectrum. The Electronic Journal of Combinatorics 15(1): R74
[5] Boulet R, Jouve B, Rossi F, Villa N (2008) Batch kernel SOM and related Laplacian methods for social network analysis. Neurocomputing 71 (7-9): 1257-1273.
55
First Name Junbeum
Last Name KIM
Laboratory CREIDD, UTT
Address T221, CREIDD Research Centre on Environmental
Studies & Sustainability
Department of Humanities, Environment & Information Technology
UMR CNRS 6279, University of Technology of Troyes
12 rue, Marie Curie, BP 2060, Troyes Cedex, 10010, France
Institution Institution University of Technology of Troyes
Tel +33 3 25 71 80 06
Fax +33 3 25-71 76 98
E.mail junbeum.kim@utt.fr
URL http://www.utt.fr
Session field Humanities Sciences / Humanities
Research Field Environmental Science and Engineering, Industrial Ecology,
life cycle assessment
Current one of my researches is about social life cycle assessment and “Social networks - co-authorship networks
and analysis in industrial ecology and sustainable science and engineering area”. Scientific publications are one
of the most tangible and well documented forms of scientific collaboration. Many scientific collaboration networks
have been extensively studied from different perspectives, such as degree analysis or centrality. However there
is any study of the scientific collaboration network in industrial ecology and sustainable science and engineering
research. For this reason, I am collecting publication data from publications between 1980 and early 2013 from
several journals and analyze and visualize them using a network analysis software.
[1] unbeum Kim, Yi Yang, Junghan Bae, and Sangwon Suh, The Importance of Normalization References in
LCA-based Policy Decision Support. (accepted, in press, Journal of Industrial Ecology).
[2] Jinwook Chung and Junbeum Kim, Assessment of Best Available Technology (BAT) for Wastewater Facilities
in Leather Tanning and Finishing Industry, Resources, Conservation and Recycling, 2013, 70, 32-37.
[3] Yi Yang, Junghan Bae, Junbeum Kim and Sangwon Suh, Replacing gasoline with corn ethanol results in
significant environmental problem-shifting. Environ. Sci. Technol., 2012, 46 (7), 367-3678.
[4] Inho Yeo, Junbeum Kim, Sukkyo Kang, Jinbeum Kim, Evaluation and Comparison Study of Carbon Footprint
of High School Students : Focused on Commute to School in Big, Middle, Small Size City, The Environmental
Education, Vol. 25, 1, 2012, pp. 15-24.
[5] Junbeum Kim, Kwangho Park, Yongwoo Hwang, and Ildo Park, Sustainable Manufacturing : A Case Study
of the Forklift Painting Process, International Journal of Production Research, Vol. 48, No. 10, 15 May 2010,
3061–3078.
56
Poster Title Co-authorship Networks in Industrial Ecology Domains
Poster Abstract Network theory and studies have developed considerably since beginning in the 1950’s.
It has been used widely in electrical engineering, computer science, engineering economics, social science,
business applications (for example, modeling increasingly complex inventory and logistics systems) and biology, where it has increasingly proven to be a powerful tool in systems ecology and in enabling understanding of complex metabolic pathways and processes. In this study, we collected the co-authorship data and
keywords from the Journal of Industrial Ecology (from volume 1, issue 1 in 1997 to volume 16, issue 5 in 2012)
and International Journal of Life Cycle Assessment (from volume 1, issue 1 in 1996 to volume 17, issue 9 in
2012). Based on the collected dada, we evaluated co-authorship network characteristics, such as, sets of key
players, closeness degree centrality, closeness centrality, betweenness centrality, eigenvector centrality, and
clustering coefficient.
57
First Name Hao
Last Name KUOCHEN
Address No.300, Jhongda Rd., Jhongli City, Taoyuan County 32001,
Taiwan (R.O.C.)
Tel +886-3-422-7151 ext 65602
Fax +886-3-422-2044
E.mail kuochen@ncu.edu.tw
URL http://www.cc.ncu.edu.tw/ kuochen/
Research Field Geosciences
Tectonics: the process of mountain building, 2D and 3D travel-time tomography, Seismic anisotropy, 3D full
waveform modeling, Petrology and seismic structures
[1] Kuo-Chen, H., F. Wu, D. M. Jenkins, J. Mechie, S. Roecker, C.-Y.Wang, and B.-S. Huang (2012) Seismic evidence for the α-β quartz transition beneath Taiwan from Vp/Vs tomography, Geophys. Res. Lett.,
doi:10.1029/2012GL053649.
[2] Kuo-Chen, H., F. T. Wu, and S. W. Roecker (2012) Three-Dimensional P Velocity Structures of the Lithosphere
Beneath Taiwan from the Analysis of TAIGER and Related Seismic Datasets, J. Geophys. Res., 117, B06306,
doi:10.1029/2011JB009108.
[3] Chen, P.-F., C.R. Bina, H. Kuo-Chen, F.T. Wu, C.-Y. Wang, B.-S Huang, C.-H. Chen, and W.-T. Liang (2012)
Slab-Induced Waveform Effects as Revealed by the TAIGER Seismic Array : Evidence of Slab beneath Central
Taiwan, Phy. Earth Planet. In., 196-197, 62-74.
[4] Huang, B.-S., P.-F. Chen, H. Kuo-Chen, K.-H. Kim., and T.-L. Teng (2012) Significant Contribution of the
Shallow Crust to Seismic PKP Travel-Time Residuals and Implications : An Example from Taiwan and Nearby
Islands, J. Asian Earth Sci., 46, 86-91.
[5] Kuo-Chen, H., F. T. Wu, D. Okaya, B.-S. Huang, and W.-T. Liang (2009) SKS/SKKS Splitting and Taiwan Orogeny, Geophys. Res. Lett., doi:10.1029/2009GL038148.
Poster Title Studies of crystal structures and earthquake precursors in Taiwan
Poster Abstract Taiwan is known for natural disasters occurring frequently, such as earthquakes, landslides,
and typhoons. Historically, numerous damage earthquakes occurred in and around Taiwan and those seismogenic zones are related to the convergence of the Philippine Sea and the Eurasian plates. However, fully understanding the geometries of those seismogenic zones are still incapable because of limited geological and geophysical
information of the sub-surface. For this reason, in 2006-2009, we collaborated with geoscientists in USA, Taiwan,
France, and Japan to conduct several geophysical experiments to image the sub-surface of Taiwan. The significantly crustal deformation, the plate boundary between the Philippine Sea and Eurasian plates, rock properties,
and seismicity are revealed in these experiments, which are the basic knowledge for earthquake disaster mitigation. Besides the fundamental geophysical survey, we conduct a geochemical experiment to capture earthquake precursors near the plate boundary in eastern Taiwan. A long-term monitoring of groundwater radon has
been conducted since 2003. Until now, we have successfully captured several radon precursors for earthquake
magnitude greater than five. We hypothesized that the dilation of brittle rock mass occurred at a rate faster than
the recharge of pore water and gas saturation developed in newly created cracks preceding the earthquake.
58
First Name Wen-Sung
Last Name LAI
Laboratory Laboratory of Integrated Neuroscience and Ethology
Address 1 Roosevelt Road, Sec. 4, Taipei 10617, Taiwan
Tel +886-2-3366-3112
Fax +886-2-2362-9909
E.mail wslai@ntu.edu.tw
Research Field Behavioral neuroscience, neurobiology of schizophrenia, social neuroscience,
biopsychology
Our current research interests in the Laboratory of Integrated Neuroscience and Ethology include
(1) to study mouse models of psychiatric disorders and the role of AKT1 and other schizophrenia candidate
genes in the pathogenesis of schizophrenia,
(2) to investigate higher cognitive functions and reward learning during decision making in both mice and
humans, and,
(3) to study social neuroscience and the neural basis of social learning and memory using hamsters as a model
system.
[1] Chen, Y.W., Kao, H.Y., Min, M.Y., Lai, W.S.* A sex- and region-specific role of Akt1 in the modulation of
methamphetamine-induced hyperlocomotion and striatal neuronal activity: implications in schizophrenia
and methamphetamine-induced psychosis. Schizophrenia Bulletin (E-publication : March 8, 2013 ; SCI, DOI:
10.1093/schbul/sbt031).
[2] Hao, C.W., Lai, W.S., Ho, C.T., Sheen, L.Y. Antidepressant-like effect of lemon essential oil is through a modulation in the levels of norepinephrine, dopamine, and serotonin in mice: use of the tail suspension test. Journal
of Functional Foods, 5, 370-379, 2013.
[3] Chen, Y.C., Chen, Y.W., Hus, Y.F., Chang, W.T., Hsiao C.K., Min, M.Y., Lai, W.S.* AKT1 deficiency modulates
reward learning and reward prediction error in Mice. Genes, Brain and Behavior, 11, 157-169, 2012.
[4] Chen, Y.W., Lai, W.S.* Behavioral phenotyping of v-akt murine thymoma viral oncogene homolog 1-deficient
mice reveals a sex-specific prepulse inhibition deficit in females that can be partially alleviated by glycogen
synthase kinase-3 inhibitors but not by antipsychotics. Neuroscience, 174, 178-189, 2011 (The cover of this
issue).
[5] Chen, Y.C., Lai, W.S.* Behavioural phenotyping of dopamine transporter knockdown mice using local small
interference RNA. Behavioural Brain Research, 214(2), 475-479, 2010.
59
Poster Title An integrated approach towards understanding the biopsychology of the mind: The
LINE and our ongoing projects
Poster Abstract “Though this be madness, yet there is method in’t.” – William Shakespeare
As pointed out by Nobel Laureate Dr. Eric Kandel, “Understanding the biology of mental illness would be a
paradigm shift in our thinking about mind…..…. it would also tell us more about who we are and how we
function”. I believe that the biology of the mind will be one of the most fascinating and challenging topics for
this century. In collaboration with human studies, animal model is a powerful/alterative approach to elucidate
causal relationships from gene, to neurons, to brain, to mental illness, and hopefully to the mind. Breeding
mice that carry schizophrenia susceptibility gene(s) and develop schizophrenia-like symptoms help researchers better understand the causal relationship of susceptibility gene(s) for schizophrenia and the pathogenesis
of this complicated disorder. Thus, the central focus of my laboratory aims at investigating the biopsychological functions of AKT1 and other schizophrenia susceptibility genes in mice. Our ultimate concern is to bridge
the most fundamental element of an organism to higher level of mental functions using animal models as a
tool. In the study of etiology of schizophrenia, this approach shall be the “method” to figure it out piece by
piece.
60
First Name Gwen
Last Name LE COR
Laboratory EA 1569 Transferts critiques et dynamique des savoirs.
Adress Université Paris 8
2 rue de la Liberté - 93 526 Saint-Denis
Institution Université Paris 8
Tel + 33 1 49 40 73 21
Fax + 33 1 49 40 70 41
E.mail gwen.le-cor@univ-paris8.fr
Session field Social Sciences /Humanities
Research Field American literature
Statement of your research interests Contemporary American literature and science: I am interested in the
way science and literature interact, intersect and reflect on one another, as well as in the flickering forms these
interactions produce. More generally, my research focuses on hybridity in contemporary American literature
(text/image or air-text chimeras, science/literature).
[1] Le Cor, Gwen, Le Grand, Benedicte. “Disruptive Use of Hyperlinks in Electronic Literature : Joint Analysis
from Literature and Computer Science Worlds” 2013. To appear in éditions Hermès-Lavoisier.
[2] Le Cor, Gwen “The Critical Voice and the Narrative Voice: Robert Penn Warren’s Essay on Coleridge and All
the King’s Men.” Mississippi Quarterly: the Journal of Southern Culture 63.1, (Winter 2010). Mississippi State:
Mississippi State University, 119-133.
[3] Le Cor, Gwen “Vision in Robert Penn Warren’s Poetry” rWp : An Annual of Robert Penn Warren Studies, 6
(2006). Western Kentucky University, 47-56.
[4] Le Cor, Gwen « L’écriture géologique de la mémoire dans les romans de Robert Penn Warren. » Cercles :
Revue pluridisciplinaire du monde anglophone. 23/2012.
[5] Le Cor, Gwen « “We will not stop looking,” parcours visuels et narratifs dans Extremely Loud & Incredibly
Close de Jonathan Safran Foer. » Théorie-Littérature-Epistémologie, vol. 28, 2011, La vérité en fiction, Presses
Universitaires de Vincennes. 2012. 81-98.
0 The Esthetics of Nonlinearity and Nonlinear Dynamical Systems : Liquid Text in Electronic Literature
Poster Abstract Starting from the premise that second generation electronic literature exhibits the charac-
teristics of nonlinear systems, this poster seeks to explore the flow of text which fleetingly hangs on screen.
It focuses more specifically on how the loss of stability impacts the texts and the way we read the works.
Using Stephanie Strickland’s slippingglimpse as a tutor text, this analysis examines how artistic creations can
provide an indirect esthetic answer to theoretical questionings on dynamical systems. The poem reconfigures
itself with each reading, therefore calling for a form of self-reflexive chaotic reading. The self-reflexivity is exhibited both in the pointer device and in the use of coastal-chreods. The pointer questions what can be called
the “arrow of reading,” while the chreods—translated into video loops of waves—provide esthetic recurrence
within a nonlinear reading experience.
61
First Name Shih-Yu
Last Name LEE
Laboratory Research Center of Environmental Changes
Address 128 Academia Rd. Nankang, Taipei, Taiwan
Institution Academia Sinica
Tel +886-2787-1925
Fax +886-2787-1924
E.mail shihyu@gate.sinica.edu.tw
Session title Disaster prevention /prediction
Research Field Climate modeling
My research interests include climate change of the past and future. I am particularly interested in how different factors influence climate change; what the past can reveal about the way climate system works, and how
future climate will impact the environment and society. Specific topical interests including Low-high latitude
climate teleconnection, ocean-atmosphere interactions, paleoclimate dynamics.
[1] Lee, S.-Y., J.C.H. Chiang, K. Matsumoto, and K. Tokos, 2011, Southern Ocean wind response to North Atlantic cooling and the rise in atmospheric CO2 : Modeling perspective and paleoceanographic implications”.
Paleoceaonography, 26, PA1214, doi:10.1029/ 2010PA002004.
[2] Lee, S.-Y. and Poulsen, C.J., 2009, Obliquity and precessional forcing of continental snowfall and melt,
Quaternary Science Reviews, 28, 2663-2674
[3] Lee, S.-Y. and Poulsen, C.J., 2008, Amplification of obliquity forcing through mean-annual and seasonal
atmospheric feedback, Climate of the Past, 4, 205-231.
Poster Title Interhemispheric gradient and tropical climate changes : climate teleconnections
in the past, present and the future
Poster Abstract The tropical sea surface temperature (SST) gradient is an important indicator of the state
of the tropical marine climate; this is particularly true for the cross-equatorial meridional SST gradient that
strongly controls the position of the Atlantic and Pacific ITCZs. Some recent lines of evidence - from both observation and climate modeling - have suggested that the meridional SST gradient (and my implication the position of the ITCZ) can be influence by the extratropics, specifically from a relative contrast in forcing between
the northern and southern hemispheres. In light of the importance of ITCZ position to the location and intensity
of rainfall, the question I pose here is whether or not this idea can be usefully applied to understanding 20th
century and future tropical climate change, focusing specifically on the Atlantic and Pacific.
62
First Name Wei-Li
Last Name LEE
Laboratory Institute of Physics
Address Institute of Physics, Academia Sinica / 128 Sec. 2, Academia Rd.,
Nankang, Taipei 11529, Taiwan
Tel +886-2-2789-6700
Fax +886-2-2789-2443
E.mail wlee@phys.sinica.edu.tw
URL http://www.phys.sinica.edu.tw/ nslab/
Research Field Physics, experimental condensed matter physics, low temperature physics
1. Transport property in novel materials, including strongly correlated electronics system, multiferroics,
topological insulator,etc.
2. Graphene-based electronics, spintronics and spin-related transport phenomena in novel materials and nanostructured systems.
3. Development of unconventional nanofabrication technique.
[1] 1. F. T. Huang, M. W. Chu, H. H. Kung, W. L. Lee, R. Sankar, S. C. Liou, K. K. Wu, Y. K. Kuo, and F. C. Chou*,
“Nonstoichiometric doping and Bi antisite defect in single crystal Bi2Se3”, Phys. Rev. B 86, 081104® (2012).
(Editors’ Suggestions)
[2] 2. C. R. Wang, W. S. Lu, L. Hao, W. L. Lee*, T. K. Lee, F. Lin, I. C. Cheng and J. Z. Chen, “Enhanced thermoelectric power in dual-gated bilayer graphene”, Phys. Rev. Lett. 107, 186602 (2011).
[3] C. C. Ho, P. Y. Chen, K. H. Lin, W. T. Juan* and W. L.Lee*,“Fabrication of monolayer of polymer/nanospheres
hybrid at a water-air interface”, ACS Applied Materials & Interfaces 3, 204 (2011).
[4] Chang-Ran Wang, Wen-Sen Lu and Wei-Li Lee, "Transverse Thermoelectric Conductivity of Bilayer Graphene in Quantum Hall Regime", Phys. Rev. B Rapid Communications 82, 121406® (2010).
[5] Chi-Chih Ho, Tung-Wu Hsieh, Hsiang-Hsi Kung, Wen-Tau Juan, Keng-Hui Lin and W. L. Lee*, “Reduced
saturation magnetization in cobalt antidot thin films prepared by polyethylene oxide-assisted self-assembly of
polystyrene nanospheres”, Appl. Phys. Lett. 96, 122504 (2010).
Poster Title Demonstration of Field-Effect Thermoelectricity in Dual-Gated Bilayer Graphene
Poster Abstract The “field-effect thermoelectricity” is demonstrated for the first time in experiment. When
applying a perpendicular electric field (D) on a bilayer graphene, the thermoelectric power (TEP) can be amplified more than 4 folds while the carrier density remains the same. The value of TEP is comparable to or
exceeding several known low temperature thermoelectric materials. The physical mechanism is rooted in the
band-gap opening due to the inversion symmetry breaking by D, which largely increases the band curvature
near the band edges. On the other hand, its polarity can be readily tuned by the gate voltage to be either
electron-type or hole-type. Our results open up a new possibility in thermoelectric application using graphenebased device.
63
First Name Zong-Rong
Last Name LEE
Position held Associate Research Fellow
Laboratory Institute of Sociology
Address No. 128 Academia Road. Section 2 Taipei, 115 Taiwan
Tel +886-2-2652-5145
Fax +886-2-2652-5050
E.mail zlee@sinica.edu.tw
Research Field Sociology
Trained as an economic and organization sociologist, my research interest focuses on the sociological understanding of individual and corporate market behaviors with the help of analytical tool of social network
analysis. My recent research topics include the kinship network analysis for major business elites in Taiwan,
social networks and financial behaviors, the temporal dynamics of intercorporate networks evolution, and the
spatial dimension of social networks.
[1] Zong-Rong Lee. (2012). “Exploring Social Mechanisms behind Risky Financial Investments: Social Capital
and Participation in Stock Markets and Mutual Funds.” Journal of Social Sciences and Philosophy 24(4): 439467
[2] Zong-Rong Lee. (2011). “The Determinants of Kinship Networks in Taiwanese Business Groups.” Taiwanese Journal of Sociology 46: 115-166
[3] Zong-Rong Lee. (2009). “Institutional Transition and Market Networks: An Historical Investigation of Interlocking Directorates of Big Businesses in Taiwan, 1962-2003” Taiwanese Sociology 17:101-160
[4] Zong-Rong Lee*, Chyi-In Wu, Yu-Ting Huang, 2012, “Exploring the antecedents and effects of structural
holes in youth friendship network”, editor(s) : Chin-Chun Yi, The Psychological Well-being of East Asian Youth :
From Early Adolescence to Young Adulthood, pp. 109-130, New York : Springer Press.
[5] Zong-Rong Lee and Thijs Velema. (forthcoming). “Between State Power and Familism: the Directorate Interlock Network in Taiwan throughout the Twentieth Century.” In The Power of Corporate Networks: A Comparative and Historical Perspective, edited by Gerarda Westerhuis and Thomas David, Routledge
64
First Name Sebastien
Last Name LEVENEUR
Laboratory LSPC-INSA de Rouen
Address 685 avenue de l’université,
BP 08, 76801 Saint-Etienne-du-Rouvray CEDEX
Institution INSA de Rouen
Tel +33 6 18 84 48 59
E.mail sebastien.leveneur@insa-rouen.fr
Research Field Process intensification, Process safety, Valorization of biomass
[1] S. Leveneur, M. Thones, J.-P. Hébert, B. Taouk, T. Salmi, “From Kinetic study to thermal safety assessment:
application to peroxyformic acid synthesis”, Industrial & Engineering Chemistry Research, Vol. 51(43) (2012)
13999–14007.
[2] S. Leveneur, C. A. de Araujo Filho, L. Estel, T. Salmi, “Modeling of a liquid-liquid-solid heterogeneous reaction system: application to the synthesis of peroxy fatty acids”, Industrial & Engineering Chemistry Research,
Vol. 51(1) (2012) 189–201.
[3] S. Leveneur, J. Wärnå, K. Eränen, T. Salmi, Green process technology for peroxycarboxylic acids: estimation
of kinetic and dispersion parameters aided by RTD measurements : green synthesis of peroxycarboxylic acids,
Chemical Engineering Science, Vol. 66 (2011) 1038–1050.
[4] S. Leveneur, J. Wärnå, T. Salmi, D. Yu. Murzin, L. Estel, Interaction of Intrinsic Kinetics and Internal Mass
Transfer in Porous Ion-Exchange Catalysts : Green Synthesis of Peroxycarboxylic Acids, Chemical Engineering
Science, Volume 64, Issue 19, October 2009, Pages 4104-4114.
[5] S. Leveneur, T. Salmi, N. Musakka, J. Wärnå, Kinetic Study of Decomposition of Peroxypropionic acid in
Liquid-Phase through Direct Analysis of Decomposition Products in Gas Phase, Chemical Engineering Science,
Volume 62, Issues 18-20, September-October 2007, Pages 5007-5012.
Poster title Safety and process intensification
Poster abstract The goal is to develop a safe and green continuous process for the production of bio-lubri-
cant, particularly epoxidized vegetable oils. This reaction occurs in heterogeneous liquid-liquid phase, where
the peroxyformic acid formed in the aqueous phase transfers to the organic one to epoxidize the unsaturated
vegetable oils. Even though this oxidation way is safer than the use of oxygen gas, the presence of peroxide
species in the reaction mixture could lead to a thermal runway at high reaction temperature or in presence
of impurities. Indeed, such peroxides could undergo some decomposition reactions which are exothermic.
To determine the maximum reaction temperature, micro-calorimetric measurement will be performed. The
knowledge of the kinetic, thermodynamic and mass transfer parameters is needed to build a robust model
to estimate these parameters. Based on the literature review and on our knowledge, cation exchange resins
are the more suitable catalyst for this reaction because it does not initiate the peroxide decomposition, the
ring opening and greener than the traditional sulfuric acid. The design of a continuous catalytic reactor will be
performed to improve the production of such compounds.
65
First Name Chien-Neng
Last Name LIAO
Laboratory Department of Materials Science and Engineering
Address 101 Sec. 2 Kuang-Fu Road Hsinchu, 30013 Taiwan Taiwan
Institution National Tsing Hua University
Tel +886-3-5715-131 EXT 33843
Fax +886-3-5722-366
E.mail cnliao@mx.nthu.edu.tw
URL http://www.mse.nthu.edu.tw/ cnliao/…
Research Field Material science
My research interests are mainly focused on electromigration of copper interconnects in integrated circuits
and nanocrystalline thermoelectric materials/devices. Our goal is investigate current-driven atomic diffusion
in Cu by using in situ transmission electron microscopy. We have found that the presence of triple junctions of
twin boundaries and grain boundaries are able to impede current-driven atomic transport at grain boundaries,
which may suppress electromigration-induced failure of Cu lines in integrated circuits. More recently, we are
exploring the stability of nanoscale twin in copper under electric current stressing. In addition, we are also
working on electric current induced defect elimination in bismuth telluride based thermoelectric materials.
[1] K. C. Chen, W. W. Wu, C. N. Liao, L. J. Chen and K. N. Tu, (2008) “Observation of Atomic Diffusion at Twinmodified Grain Boundaries in Copper”, Science, 321, 1066.
[2] C. N. Liao and L. C. Wu, (2009) “Enhancement of carrier transport properties of BixSb2-xTe3 compounds by
electrical sintering process”, Appl. Phys. Lett., 95, 052112.
[3] C. N. Liao, W. T. Chen and C. H. Lee, (2010) “Polarity effect on interfacial reactions at soldered junctions of
electrically stressed thermoelectric modules”, Appl. Phys. Lett. 97, 241906.
[4] T. C. Chan, K. C. Chen and C. N. Liao, (2011) “Surface roughness reduction of nanocrystalline Cu thin films
by electrical stressing treatment”, Appl. Phys. Lett., 98, 181902.
[5] C. N. Liao, Y. C. Lu and D. Xu, (2013) “Modulation of crystallographic texture and twinning structure of Cu
nanowires by electrodeposition”, J. Electrochem. Soc. 160 (6), D207.
66
First Name Chih-Ping
Last Name LIN
Laboratory Geo-imaing and Geo-nerve Laboratory
Address 1001 Ta-Hsueh Rd., Dept. of Civil Engr., Hsinchu 300, Taiwan
Institution National Chiao Tung University
Tel +886-3-5131-574
Fax +886-3-5716-257
E.mail cplin@mail.nctu.edu.tw
Statement of your research interests My primary research interests are engineering monitoring based
on electromagnetic time domain reflectometry (TDR) and developments and applications of near-surface geophysics to engineering problems. Current research projects are focusing on solving geotechnical and water
resources-related problems using geophysical methods, including quality inspection of ground improvement,
non-destructive evaluation of dams, subsurface imaging of soil water content, suspended sediment monitoring in rivers and reservoirs, and scour monitoring.
[1] Lin, C.-H., Lin, C.-P., Drnevich, V. P. (2012), “TDR Method for Compaction Quality Control : Multi Evaluation
and Sources of Error,” Geotechnical Testing Journal, Vol. 35, No. 5, p. 817-826.
[2] Lin, C.-H. and Lin, C.-P. (2012), “Metamorphosing the SASW Method by 2-D Wavefield Transformation,”
Journal of Geotechnical and Geoenvironmental Engineering, Vol. 138, No. 8, p. 1027 1032.
[3] Chung, C.-C., and Lin, C.-P. (2011), “High Concentration Suspended Sediment Measurement using Time
Domain Reflectometry,” Journal of Hydrology, Vol. 401, 134-144.
[4] Chung, C.-C and Lin, C.-P. (2009), “Apparent Dielectric Constant and Effective Frequency of TDR Measurements : Influencing Factors and Comparison”, Vadose Zone Journal, Vol. 8, No. 3., pp. 548-556.
[5] Lin, C.-P., Tang, S.-H., Lin, W.-C., and Chung, C.-C. (2009), “Quantification of Cable Deformation with TDR:
Implications to Localized shear deformation Monitoring,” Journal of Geotechnical and Geoenvironmental Engineering, Vol. 135, No. 1., pp. 143-152.
67
First Name Keng-Hui
Last Name LIN
Position held Associate Research Fellow
Laboratory Soft Matter and Cell-Matrix Interactions in 3D
Address 128 Academia Road, Sec. 2 Institute of Physics,
Academia Sinica, Taipei, Taiwan
Tel +886-2-2789-6763
Fax +886-2-2788-9829
E.mail khlin@phys.sinica.edu.tw
URL http://www.phys.sinica.edu.tw/ khlin
Research Field Soft matter physics, cell-material interactions in 3D, solid foam mechanics
[1] Lin J-Y, Lin W-J, Hong W-H, Hung W-C, Nowotarski SH, Gouveia SM, Cristo I, Lin K-H*. (2011) Morphology and organization of tissue cells in 3D microenvironment of monodisperse foam scaffolds. Soft Matter 7:
10010-10016.
[2] Chung K-Y, Mishra NC, Wang C-C, Lin F-H, Lin K-H* (2009) Fabricating scaffolds by microfluidics. Biomicrofluidics 3: 022403.
Poster Title Morphology of fibroblasts on negatively curved substrate with tunable stiffiness
Poster Abstract We used liquid foam as a template to create scaffolds of uniform pores for cell culture. We
can tune the stiffness of the scaffolds and pore sizes. We investigated the morphology of fibroblasts and found
that cells sense local stiffness, rather than overall scaffold stiffness. In addition, we find that when pore sizes
increase, cells exhibit longer cell length and elongation. When the pore size become smaller, the distribution
of cytoskeleton and focal adhesion does not confine in a plane but is truly 3D. Also, at the smaller pore size,
the nucleus is less "squeezed" in comparison with 2D or in larger pore size. This novel 3D scaffold can be an
interesting assay to study cell-matrix interactions in 3D.
68
First Name Shauping
Last Name LIN
Laboratory Institute of Biotechnology, Taipei, Taiwan
Address 4F, No. 81, Chang-Xing St., Taipei 106, Taiwan
Tel +886-2-3366-6005
Fax +886-2-3366-6001
E.mail shaupinglin@ntu.edu.tw
URL http://www.iob.ntu.edu.tw/people/bi…
Research Field Epigenetics and Development
Using mouse, human and chicken germ cells and stem cells as models, to study how epigenetic regulatory
machineries (including but not limited to DNA methylation, functional non-coding RNAs and chromatin modifications) regulate gene expressions and thus cellular function and identity.
[1] Hung-Fu Liao, Kang-Yu Tai, Wendy S.-C. Chen, Luca, C.W. Cheng, and Shau-Ping Lin*. Functions of DNA
methyltransferase 3-like in germ cells and beyond. Biology of the Cell. 2012, 104:571-587.
[2] Ching-Yu Chuang, Kuo-I Lin, Michael Hsiao, Lee Stone, Hsin-Fu Chen, Yen-Hua Huang, Shau-Ping Lin*,
Hong-Nerng Ho and Hung-Chih Kuo*. Meiotic competent human germ cell-like cells derived from human
embryonic stem cells induced by BMP4/WNT3A signaling and OCT4/EpCAM selection. Journal of Biological
Sciences. 2012. 27 ;287(18):14389-401.
[3] Ooi S. K.T, Qiu C, Bernstein E, Li K, Jia D, Yang Z, Erdjument-Bromage H, Tempst P, Lin S.P, Allis C D, Cheng
X and Bestor T.H., DNMT3L Connects Unmethylated Lysine 4 of Histone H3 To De Novo Methylation of DNA.
Nature. 448(7154):714-7 (2007). IF=34.48 Cited : 511 times.
[4] Lin SP, Coan P, da Rocha ST, Seitz H, Cavaille J, Teng PW, Takada S, Ferguson-Smith AC. Differential regulation of imprinting in the murine embryo and placenta by the Dlk1-Dio3 imprinting control region. Development.
2007 Jan ; 134(2) : 417-26. (SCI) IF=6.898, Cited 47 times
[5] Lin S.P, Youngson N, Takada S, Seitz H, Reik W, Paulsen M, Cavaille J, and Ferguson-Smith AC. Asymmetric
regulationof imprinting on the maternal and paternal chromosomes at the Dlk1-Gtl2 imprinted cluster on
mouse chromosome 12. Nature Genetics, 35: 97-102 (2003). IF=34.284 ; Cited : 259 times
mammals.(2006/08/08-2024/03/02)
69
First Name Thunghong
Last Name LIN
Position held Assistant Research Fellow
Laboratory Institute of Sociology
Address: Institute of sociology, 128 Sec. 2 Academia Rd., Nankang, Taipei
11529, Taiwan
Tel +886-2-6614-5127
Fax +886-2-6614-5050
E.mail zoo42@gate.sinica.edu.tw
URL http://www.ios.sinica.edu.tw/ios/E/…
Research Field Sociology, Political Science
I am interested in Social Stratification, Political Sociology, Comparative Political Economy, Sociology of Disaster and China Study. I analyze the social survey datasets of Taiwan, China, Hong Kong, Korea and Japan.
Most of my publications is in Chinese. There are some English papers:
[1] Thung-hong Lin, 2011, “Governing Disaster: Political Institution, Social Inequality and Human Vulnerability”,
paper presented at 2011 Annual Meeting of American Sociological Association, Las Vegas: American Sociological Association, 2011-08-20 2011-08-24. L
[2] Lin, Thunghong, 2012, “When Classes Met Trade : Cross-straits Trade and Class Inequality in Taiwan”,
paper presented at 2012 Annual Meeting of American Sociological Association, Denver, CO, US : American
Sociological Association, 2012-08-17 2012-08-21.
[3] Thung-hong Lin, Xiaogang Wu, 2009, “The Transformation of Chinese Class Structure : 1978-2005”, Social
Transformations in Chinese Societies, 5 : 82-112.
Poster Title Governing Natural Disaster
Poster Abstract The paper argues that state capacity and regime type, two fundamental elements of modern
political institution, shape the allocation of natural disaster vulnerability in the global human community. For
rule and revenue, political elites have incentive to build-up relevant state capacity preventing disaster impacts
on the population and property. The incentive of the elites and the capacity protecting citizens shall be stronger
under democratic competitive elections. A panel data that includes 150 countries from 1995 to 2009 are used
to illustrate the relationship between state capacity, democracy, and the impact of disaster. After controlling
density and continuity of natural disaster hazards, the empirical findings from the multilevel models imply
that strong state capacity and democratic regime is associated with the lower disaster death and victim tolls.
Besides, strong state capacity effectively reduces human vulnerability especially in democracy.
70
First Name Kirone
Last Name MALLICK
Laboratory Institut de physique théorique
Address Orme des Merisiers CEA Saclay 91191 Gif sur Yvette
Institution CEA
Tel +33 1 69 08 14 51
Fax +33 1 69 08 81 20
E.mail kirone.mallick@cea.fr
Research Field Physics
[1] A. Lau, D. Lacoste, K. Mallick: Non-equilibrium fluctuations and mechanochemical couplings of a molecular
motor Phys. Rev. Lett. 99, 158102 (2007).
[2] S. Prolhac, K. Mallick: Current Fluctuations in the Exclusion Process and Bethe Ansatz J.Phys. A: Math.
Theor. 41, 175002 (2008).
[3] T. Chou, K. Mallick, R. K. P. Zia: Non-equilibrium statistical mechanics: from a paradigmatic model to biological transport, Rep. Prog. Phys. 74, 116601 (2011).
[4] J. Olejarz, P. L. Krapivsky, S. Redner, K. Mallick: Growth inside a corne: The limiting interface shape, Phys.
Rev. Lett. 108, 016102 (2012).
[5] M. Gorissen, A. Lazarescu,K. Mallick,2 and Carlo Vanderzande xact Current Statistics of the Asymmetric
Simple Exclusion Process with Open Boundaries Phys Rev Lett 109, 170601 (2012)
Poster Title Recent Developments in Non-equilibrium Statistical Physics
Poster Abstract Recent Developments in Nonequilibrium Statistical Physics A complex system maintained
out of equilibrium through its interactions with the environment will usually evolve to a non-equilibrium steady
state with a non-vanishing macroscopic current (a metal conductor subject to a driving field in its bulk, or to
a difference of potentials between its boundaries, provides a simple example). Due to the presence of this
stationary current, time-reversal invariance is violated. This is a situation which lies beyond the realm of
traditional thermodynamics and the principles of equilibrium statistical mechanics do not apply. There exists
no fundamental theory or framework (a la Gibbs-Boltzmann) that would allow us to predict the value of the
current and of its fluctuations from first principles. Nevertheless, during the last two decades, substantial
progress has been made towards a statistical theory of non-equilibrium systems. The aim of this lecture is to
explain some remarkable recent results valid for sytems far from equilibrium: the Work Identities (Jarzynski,
Crooks) and the Fluctuation Theorem (Cohen, Evans, Gallavotti and Morriss), that quantify transient violations
of the second principle. These seminal results can be applied to various physical situations and put the emphasis of some mathematical objects, the large deviation functions that are expected to play for systems out
of equilibrium a role akin to that of thermodynamic potentials. We shall illustrate these concepts with some
simple systems such as the Brownian ratchet model for molecular motors and the asymmetric exclusion
process, which is considered today as the paradigm of nonequilibrium physics.
71
First Name Jérôme
Last Name MURIENNE
Laboratory "EDB" Evolution et Diversité Biologique, UMR 5174
Address Université Paul Sabatier, bat 4R1 porte 20
118 route de Narbonne 31062 Toulouse cedex 9, France
Institution CNRS
Tel +33 55 61 55 64 39
E.mail murienne@gmail.com
URL http://jmurienne.ups-tlse.fr/
Research Field Biodiversity
I am an evolutionary biologist with a primary interest in molecular phylogenetics and biogeography. My research spans a diversity of biological systems and approaches, conceptually unified by a biogeographic perspective. I investigate the evolutionary forces responsible for the current patterns of global biodiversity. In the
context of a general loss of biological diversity and global climate change, understanding why some places on
earth harbor more species richness and endemism than others has been of fundamental importance.
[1] Murienne J., Benavides L. R., Prendini L., Hormiga G., Giribet G. Forest refugia in Western and Central Africa
as “museums” of Mesozoic biodiversity. Biology Letters, 2013.
[2] Espeland, M. Murienne J.. Diversity dynamics in New Caledonia, towards the end of the museum model?.
BMC Evolutionary Biology. 11, 254, 2011.
[3] Murienne J., Edgecombe, G. D. and Giribet, G. Comparative phylogeography of the centipedes Cryptops pictus
and Cryptops niuensis in New Caledonia, Fiji and Vanuatu. Organisms Diversity & Evolution, 11, 61-74, 2011.
[4] Murienne J., Karaman I. & Giribet G. Explosive evolution of an ancient group of Cyphophthalmi (Arachnida:
Opiliones) in the Balkan Peninsula. Journal of Biogeography, 37 : 90-102, 2010.
[5] Murienne J. Testing biodiversity hypotheses in New Caledonia using phylogenetics. Journal of Biogeography, 36 (8) 1433-1434, 2009.
72
First Name Valérie
Last Name PEZO
Laboratory ISSB/Xenome
Address 5, rue Henri Desbrueres 91000 EVRY
Institution CEA
Tel +33 1 69 47 53 87
Fax +33 1 69 47 44 37
E.mail vpezo@genoscope.cns.fr
Participant Category PGM
Session title Ecology, Biodiversity and evolution
Research Field Microbiology, molecular biology, synthetic biology, xenobiology
The ultimate aim of our team is to design and engineer novel cellular components to elaborate safe GMOs (genetically modified organisms) whose in vivo generation and functionality can be strictly controlled, and which
therefore allow the development of new and advanced applications in biotechnology.
[1] De Berardinis V, Vallenet D, Castelli V, Besnard M, Pinet A, Cruaud C, Samair S, Lechaplais C, Gyapay G,
Richez C, Durot M, Kreimeyer A, Le Fèvre F, Schächter V, Pezo V, Döring V, Scarpelli C, Médigue C, Cohen GN,
Marlière P, Salanoubat M, Weissenbach J. A. Complete collection of single-gene deletion mutants of Acinetobacter baylyi ADP1. Mol Syst Biol. 2008 ;4:174.
[2] Pezo V., Louis D., Guérineau V., Lecaer J-P., Gaillon L., Mutzel R. and Ph. Marlière. A Metabolic prototype for
eliminating tryptophan from the genetic code. Scientific Reports. 2013;3:1359.
[3] Pezo V, Wu Liu F, Abramov M, Froeyen M, Herdewijn P and P Marlière. Binary Genetic Cassettes for Selecting
XNA-Templated DNA Synthesis In Vivo. accepted Angewandte
73
First Name Laurent
Last Name PRÉVOT
Laboratory Laboratoire parole et langage
Address 5 av Pasteur, 13100 Aix-en-Provence
Institution Aix Marseille Université
Tel +33 4 13 55 35 96
E.mail laurent.prevot@lpl-aix.fr
URL http://www.lpl.univ-aix.fr/
Research Field Language Sciences
Computational modeling of discourse and dialogue
[1] Afantenos, Stergos, Nicholas Asher, Farah Benamara, Myriam Bras, Cécile Fabre, Mai Ho-dac, Anne Le
Draoulec, et al. “An Empirical Resource for Discovering Cognitive Principles of Discourse Organisation: The
ANNODIS Corpus.” In Language Resources and Evaluation Conference (LREC), 2012.
[2] Huang, Chu-Ren, Nicoletta Calzolari, Aldo Gangemi, Alessandro Lenci, Alessandro Oltramari, and Laurent
Prévot. Ontology and the Lexicon, 2010.
[3] Prévot, Laurent, and Roxane Bertrand. “CoFee-Toward a Multidimensional Analysis of Conversational Feedback, the Case of French Language.” In Proceedings of the Workshop on Feedback Behaviors, 2012.
[4] Sajous, Franck, Emmanuel Navarro, Bruno Gaume, Laurent Prévot, and Yannick Chudy. “Semi-automatic
Enrichment of Crowdsourced Synonymy Networks : The WISIGOTH System Applied to Wiktionary.” Language
Resources and Evaluation (2011): 1–34.
[5] Vergez-Couret, Marianne, Laurent Prévot, and Myriam Bras. “How Different Information Sources Interact in
the Interpretation of Interleaved Discourse: The Case of Two-Step Enumerative Structures.” Discours. Revue
de Linguistique, Psycholinguistique et Informatique no. 11 (2012).
74
First Name Marc
Last Name SCIAMANNA
Laboratory LMOPS
Address 2, Rue Edouard Belin, 57070 Metz (France)
Institution SUPELEC
Tel +33 3 87 76 47 05
Fax +33 3 87 76 47 22
E.mail marc.sciamanna@supelec.fr
Research Field Physics
Photonics nonlinear optics nonlinear dynamics laser diode optical communications chaos
[1] M. VIRTE, K. PANAJOTOV, H. THIENPONT, M. SCIAMANNA, "Deterministic polarization chaos from a laser
diode". In Nature Photonics, vol 7, 60-65 (2013)
[2] A. KARSAKLIAN DAL BOSCO, D. WOLFERSBERGER, M. SCIAMANNA, "Extreme events in time-delayed nonlinear optics". In Optics Letters, 38:703-705, 2013.
[3] M. SCIAMANNA, M. VIRTE, C. MASOLLER, A. GAVRIELIDES, "Hopf bifurcation to square wave switching in
mutually coupled semiconductor lasers". In Physical Review E, 86(1):016218-1-7, 2012.
[4] V. CAULLET, N. MARSAL, D. WOLFERSBERGER, M. SCIAMANNA, "Vortex Induced Rotation Dynamics of Optical Patterns". In Physical Review Letters, 108:263903, 2012.
[5] D. RONTANI, A. LOCQUET, M. SCIAMANNA, D. CITRIN, A. UCHIDA, "Generation of Orthogonal Codes with
Chaotic Optical Systems". In Optics Letters, 36(12):2287-2289, 2011.
Poster Title Nonlinear Photonics @Supélec
Poster Abstract I will summarize some of our recent most significant achievements in theory and experiment on nonlinear photonics, in the context of the Optics and Electronics (OPTEL) department and the LMOPS
laboratory at Supélec. The reported results include the first demonstration of optical chaos from a free running
laser, the report of extreme events - so called rogue waves - in a laser diode with optical feedback, and the
dynamics of optical pattern formation in a nonlinear optical cavity pumped by a vortex light beam.
75
First Name Christophe
Last Name SERRA
Laboratory G2IP/ICPEES
Address 25 rue Becquerel F-67087 Strasbourg Cedex
Institution University of Strasbourg
Tel +33 3 68 852 718
Fax +33 3 68 852 716
E.mail ca.serra@unistra.fr
URL http://icpees.unistra.fr/caserra
Research Field Polymer Reaction Engineering
Development of new microfluidic-assisted polymer processes for the synthesis of architecture-controlled
polymers and functional microstructured polymer particles.
[1] Allouch A., S. Le Calvé and C.A. Serra, Portable, miniature, fast and high sensitive real-time analyzers: BTEX
detection, Sens. Actuators, B, 182 (2013) 446–452.
[2] Ikram I.U., C.A. Serra, N. Anton and T. Vandamme, Continuous-flow encapsulation of ketoprofen in copolymer microbeads via co-axial microfluidic device: influence of operating and material parameters on drug carrier properties, Int. J. Pharm., 441 (1) (2013) 809-817.
[3] Koehler J.M., Maerz A., Popp J., Knauer A., Kraus I., Faerber J. and C. Serra, Polyacrylamid/silver composite
particles produced via microfluidic photopolymerization for single particle-based SERS micro sensorics, Anal.
Chem., 85 (1) (2013) 313–318.
[4] Parida D., C.A. Serra, F. Bally, D.K. Garg and Y. Hoarau, Intensifying the ATRP synthesis of statistical copolymers by continuous micromixing flow techniques, Green. Proc. Synt., 6 (1) (2012) 525-532.
[5] Bally F., C. A. Serra, C. Brochon, N. Anton, T. Vandamme, G. Hadziioannou, A continuous-flow polymerization
microprocess with online SEC and inline polymer recovery by micromixer-assisted nanoprecipitation, Macromol. React. Eng., 5 (11-12) (2011) 542–547 (invited article).
Poster Title Microreaction Technology: a Tool for the Intensification of Polymerization Processes, Application to ATRP
Poster Abstract This poster presents our latest developpement aiming at the intensification of controlled/”living”
radical polymerization processes for the production of architecture-controlled (co)polymers. Intensification method relies on the use of microtubular reactors and considers both effect of operating parameters (premixing,
temperature, pressure) and microreactor geometry (coiled, flow inversion).
76
First Name Chi-Tin
Last Name SHIH
Address Department of Physics, Tunghai University 1727, Sec.4, Taiwan
Boulevard, Xitun District, Taichung 40704, Taiwan
Institution Tunghai University
Tel. +886-4-2359-0121 ext. 32127
Fax +886-4-2359-4643
E.mail shih.chi.tin@gmail.com
Research Field Biophysics
1. Structure and dynamics of the network of Drosophila brain
2. Electric transport properties of the DNA molecule
3. Analysis of the time series
[1] Chi-Tin Shih*, Stephen A. Wells, Ching-Ling Hsu, Yun-Yin Cheng, and Rudolf A. Römer*, 2012, The Interplay
of Mutations and Electronic Properties in Disease-Related Genes, Scientific Reports 2, 272 (Nature Publishing
Group).
[2] Ann-Shyn Chiang*, Chih-Yung Lin, Chao-Chun Chuang, Hsiu-Ming Chang, Chang-Huain Hsieh, Chang-Wei
Yeh, Chi-Tin Shih, Jian-Jheng Wu, Guo-Tzau Wang, Yung-Chang Chen, Cheng-Chi Wu, Guan-Yu Chen, Yu-Tai
Ching, Ping-Chang Lee, Chih-Yang Lin, Hui-Hao Lin, Chia-Chou Wu, Hao-Wei Hsu, Yun-Ann Huang, Jing-Yi Chen,
Hsin-Jung Chiang, Chun-Fang Lu, Ru-Fen Ni, Chao-Yuan Yeh, & Jenn-Kang Hwang, 2011, Three-dimensional
reconstruction of brainwide wiring networks in Drosophila at single cell resolution, Current Biology 21, 1.
[3] C. T. Shih*, Hsuan-Wen Lin, Ann-Shyn Chiang, 2011, Statistical Analysis and Modeling of the TemperatureDependent Sleep Behavior of Drosophila, Computer Physics Communication 182, 195.
[4] C. T. Shih, Y. Y. Cheng, S. Wells, Rudolf A. Römer*, and C. L. Hsu, 2011, Charge Transport in Cancer-Related
Genes and Early Carcinogenesis, Computer Physics Communication 182, 36.
[5] C. T. Shih, S. Roche, and Rudolf A. Römer*, 2008, Point Mutations Effects on Charge Transport Properties of
the Tumor-Suppressor Gene p53, Phys. Rev. Lett. 100, 018105. (95-2112-M-029-003)
77
Poster Title Toward the Drosophila Connectome : Structural Analysis of the Brain Network
Poster Abstract The brain can be conceptualized as a complex network. It is believed that the topological
structure of the brain network is closely related to the functions of the brain. Therefore, understanding the
network structure of the brain is a crucial task in neuroscience. In this report, we propose a first draft of the
network architecture of the Drosophila connectome at the mesoscopic scale. The structural network of the
Drosophila brain is constructed from a dataset of more than 20,000 single neurons in female brain assembled in the FlyCircuit database (http://www.flycircuit.tw), the most comprehensive database of single-neuron
images of the Drosophila brain to date. The nodes of the network represent mesoscopic brain regions called
Local Processing Units (LPUs). The weight of the edges connecting each node pair corresponds to the number of neurons innervating the two LPUs reciprocally. The network shows hierarchical structure, pronounced
small-world characteristics with high clustering and high global efficiency, and it is composed of six modules
corresponding to known functional domains including the sensory modalities (including olfactory, mechanoauditory, and visual), together with the pre-motor and motor centers. Based on the modular structure of the
network, we propose two models for the flow of information associated with intuitive and reasoning behaviors,
respectively.
78
First Name Martine
Last Name SIMOES
Laboratory Institut de physique du globe de Paris
Address Equipe de tectonique - Mécanique de la lithosphère (Bureau 213)
Institut de physique du globe de Paris
1 rue Jussieu 75238 Paris cedex 05 France
Institution CNRS
Tel +33 1 83 95 76 26
E.mail simoes@ipgp.fr
Active tectonics / mountain building / interactions between tectonics and surface processes / seismic hazards
Recent most important publications (5 maximum)
[1] Simoes M., O. Beyssac, Y.-G. Chen, Late Cenozoic metamorphism and mountain building in Taiwan: a
review., J. Asian Earth Sci., 46 , p 92-119, 2012. - invited review.
[2] Simoes M., J. Braun, S. Bonnet, Continental-scale erosion and transport laws: a new approach to quantitatively investigate macro-scale landscapes and associated sediment fluxes over the geological past., Geochem
Geophys. Geosyst., 11, Q09001, doi :10.1029/2010GC003121, 2010.
[3] Simoes M., J.P. Avouac, O. Beyssac, B. Goffe, K.A. Farley, Y.-G. Chen, Mountain building in Taiwan : a thermokinematic model., Journal of Geophysical Research, 112, B11405, doi:10.1029/2006JB004824, 2007.
[4] Simoes M., J.P. Avouac, Y.-G. Chen, A. K. Singhvi, C.-Y. Wang, Y.-C. Chan, M. K. Jaiswal*, S. Bernard*, Kinematic analysis of the Pakuashan fault tip fold, west central Taiwan : Shortening rate and age of folding inception., Journal of Geophysical Research, 112, B03S14, doi:10.1029/2005JB004198, 2007.
[5] Simoes M., J.P. Avouac, Y.-G. Chen, Slip rates on the Chelungpu and Chushiang thrust faults inferred from
a deformed strath terrace along the Dungpuna river, west central Taiwan., Journal of Geophysical Research,
112, B03S10, doi:10.1029/2005JB004200, 2007.
79
First Name Daniel
Last Name STOCKHOLM
Laboratory Genethon-Unit 951 Inserm-UEVE-EPHE
Address 1, rue de l’Internationale 91000 Evry
Institution Ecole pratique des hautes études
Tel +33 1 69 47 10 30
E.mail stockho@genethon.fr
Research Field Molecular and Cell Biology, Epigenetics, Imaging, Gene Therapy
[1] Yamagata Y, Parietti V, Stockholm D, Corre G, Poinsignon C, Touleimat N, Delafoy D, Besse C, Tost J, Galy
A, Paldi A. Lentiviral transduction of CD34(+) cells induces genome-wide epigenetic modifications. PLoS One.
2012;7(11)
[2] Stockholm D, Edom-Vovard F, Coutant S, Sanatine P, Yamagata Y, Corre G, Le Guillou L, Neildez-Nguyen TM,
Paldi A. Bistable cell fate specification as a result of stochastic fluctuations and collective spatial cell behaviour. PLoS One. 2010 Dec 28;5(12):e14441.
[3] Stockholm D, Benchaouir R, Picot J, Rameau P, Neildez TM, Landini G, Laplace-Builhé C, Paldi A. The origin
of phenotypic heterogeneity in a clonal cell population in vitro. PLoS One. 2007 Apr 25;2(4):e394.
[4] Stockholm D, Bartoli M, Bourg N, Raynaud F, Delevacque A, Han Y, Borel P, Seddik K, Armande N, Richard I.
A mouse model for monitoring calpain activity under physiological and pathological conditions. J Biol Chem.
2006 Dec 22;281(51):39672-80.
[] Stockholm D, Bartoli M, Sillon G, Bourg N, Davoust J, Richard I. Imaging calpain protease activity by multiphoton FRET in living mice. J Mol Biol. 2005 Feb 11;346(1):215-22.
Poster title Epigenetic modifications due to gene therapy treatments in hematopoietic stem cells
Poster Abstract Gene therapy based on HIV-derived vectors is used to treat some inherited disorders of the
blood and immune system. Vectors are particles made of parts of a virus that ensures efficient nuclear delivery
while entirely removing all coding sequences that contribute towards the replication and pathogenesis of the
virus. The stable genomic integration of a therapeutic transgene in blood cells is obtained following ex vivo transduction of hematopoietic stem cells using HIV-derived (lentiviral) vectors. Recently our team found that the ex vivo
lentiviral vector treatment causes epigenetic modifications in hematopoietic stem cells. Examples of such modifications are DNA methylation and histone modification, both of which serve to regulate gene expression without
altering the underlying DNA sequence. We found that more than 5% of the methylation sites were modified which
strongly suggests that broad epigenetic changes induced by ex vivo treatment of the cells by the medium with
cytokines and by effects of the vector, may contribute to define the vector genomic insertion site profile. This may
have consequences on the safety of gene transfer in clinical applications but such knowledge may also help to
provide new biomarkers to rationally optimize gene and cell therapy protocols.
80
First Name François
Last Name TREUSSART
Laboratory Laboratoire Aimé Cotton, CNRS UPR3321
Address Campus universitaire d’Orsay Bâtiment 505 91405 Orsay France
Institution Ecole normale supérieure de Cachan
Tel +33 1 47 40 75 55
Fax +33 1 47 40 55 57
E.mail francois.treussart@ens-cachan.fr
URL http://tinyurl.com/nanodiamants-bio…
Research Field Biophotonics
F. TREUSSART has worked for more than ten years in single emitters and nanocrystal spectroscopy, from single
molecule to single photoluminescent or non-linear nanocrystals. He started to use nitrogen-vacancy color centers
in diamond in 2003, for the production of single-photon-on-demand and its application to quantum information.
In 2006, he launched a new research direction: fluorescent diamond nanocrystal as a traceable vector for drug
delivery, and stable non-toxic label for molecular motors traffic monitoring in dendrites of neurons.
[1] N. D. Lai, O. Faklaris, D. Zheng, V. Jacques, H.-C. Chang, J. F. Roch, and F. Treussart, “Quenching nitrogen–
vacancy center photoluminescence with an infrared pulsed laser,” New J. Phys. 15(3), 033030 (2013)
[2] A. Alhaddad, C. Durieu, G. Dantelle, E. Le Cam, C. Malvy, F. Treussart, and J.-R. Bertrand, “Influence of the
Internalization Pathway on the Efficacy of siRNA Delivery by Cationic Fluorescent Nanodiamonds in the Ewing
Sarcoma Cell Model,” PLoS ONE 7(12), e52207 (2012)
[3] A. Alhaddad, M.-P. Adam, J. Botsoa, G. Dantelle, S. Perruchas, T. Gacoin, C. Mansuy, S. Lavielle, C. Malvy, F.
Treussart, and J.-R. Bertrand, “Nanodiamond as a Vector for siRNA Delivery to Ewing Sarcoma Cells,” Small
7(21), 3087–3095 (2011).
[4] J. Botsoa, T. Sauvage, M. P. Adam, P. Desgardin, E. Leoni, B. Courtois, F. Treussart, and M. F. Barthe, “Optimal
conditions for NV- center formation in type 1b diamond, using photoluminescence and positron annihilation
spectroscopies,” Phys. Rev. B 84, 125209 (2011).
[5] O. Faklaris, V. Joshi, T. Irinopoulou, P. Tauc, M. Sennour, H. Girard, C. Gesset, J.-C. Arnault, A. Thorel, P.A.
Curmi, and F. Treussart, “Photoluminescent Diamond Nanoparticles for Cell Labeling: Study of the Uptake
Mechanism in Mammalian Cells,” ACS Nano 3(12), 3955–3962 (2009)
81
Poster Title Imaging Nitrogen-Color center in diamond nanocrystals by STED microscopy
Poster Abstract The Nitrogen-Vacancy (NV) colour centre in diamond is a perfectly stable emitter under
light excitation, promising for sub-diffraction limited microscopy techniques such as STimulated Emission
Depletion (STED). A resolution of a few nanometres has been achieved using STED for a single NV centre in
bulk diamond. For spherical diamond nanocrystals (ND) in the electrostatic approximation (size ≈100 nm), the
whole particle behaves like a dipole antenna with a quasi-homogeneous inner electric field, so that STED resolution should be limited to ND size. We tested these predictions experimentally. We spincoated ND (size range
20-100 nm) on a photoetched quartz coverslip. We characterized each ND with combined optical confocal –
Atomic Force Microscope and time-intensity correlation setups, allowing for the simultaneous measurement
of the size and number of NV centers. The same ND were then imaged by STED microscopy. ND containing
single NV center resulted STED spots full width at half maximum (FWHM) size of 15 nm whatever the physical
size of the ND was. For ND containing more than one NV center, we observed multiple 15 nm-spots within ND
as small as 80 nm (confirmed by electron microscopy). These observations challenge the above-mentioned
model and are being interpreted.
82
First Name Nicolas
Last Name VUILLERME
Laboratory AGIM
Address GEM (Gerontechnology, E-health and Modelisation) team Univ.
Grenoble Alpes, AGIM laboratory,
FRE 3405 Faculty of Medicine - 38706 La Tronche cédex France
Institution Université Joseph Fourier Grenoble
Tel +33 4 76 63 71 04
Fax +33 4 76 63 74 92
E.mail nicolas.vuillerme@agim.eu
URL http://nicolas.vuillerme.perso.sfr….
Research Field Neurosciences Information Technology Engineering Sciences; e-health
I am currently developing and encouraging an interdisciplinary educational and research program which focuses on the study and the exploitation of the paradigm of perceptual supplementation. This paradigm is
jointly employed (i) as a suitable means to investigate human cognition (multisensory integration mechanisms,
brain plasticity) and (ii) as a promising instrumental solution for the conception and the deployment of technologies and services for ageing, health and autonomy (physical and physiological multimodal, embedded,
interactive sensors and actuators).
[1] Pradels, A., Pradon, D., Hlavacková, P., Diot, B., & Vuillerme, N., Sensory re-weighting in human bipedal
postural control : the effects of experimentally-induced plantar pain. PLoS ONE (2013) (in press)
[2] Franco, C., Fleury, A., Guméry, P.Y., Diot, B., Demongeot, J., & Vuillerme, N., iBalance-ABF : a Smartphonebased audio-biofeedback balance system. IEEE Transactions on Biomedical Engineering. 60 (2013) 211-215.
[3] Fouquet, Y., Franco, C., Diot, B., Demongeot, J., & Vuillerme, N., Estimation of task persistence parameter from
pervasive medical systems with censored data. IEEE Transactions on Mobile Computing . 12 (2013) 633-646.
[4] Verrel, J., Pradon, D., & Vuillerme, N., Persistence of motor-equivalent postural fluctuations during bipedal
quiet standing. PLoS ONE (2012) 7(10) : e48312.
[5] Gueguen, M., Vuillerme, N., & Isableu, B., Does the integration of haptic and visual cues reduce the effect of a biased visual reference frame on the subjective head orientation ? PLoS ONE (2012) 7(4) : e34380.
doi:10.1371/journal.pone.0034380.
83
Poster Title Exploiting the paradigm of perceptual supplementation to investigate human
cognition and to develop smart technologies for health and autonomy
Poster Abstract We present a research program that focuses on studying and exploiting of the paradigm of
“perceptual supplementation”, which is jointly employed (i) as a suitable and relevant means to investigate
human cognition and (ii) as a promising instrumental solution for the development of technologies for health
and autonomy. Hence, this research program presents a truly interdisciplinary feature with a dimension of
basic research in the field of Neurosciences and a dimension of applied research in the field of Information
and Communication Engineering Technology. Two complementary goals, (i) scientific and (ii) technological, are
pursued. The first objective is to investigate in more depth multisensory integration mechanisms involved in
the control of perceptive, spatial, postural and motor behaviours and their changes as results of normal aging, chronic diseases, pathologies and/or accidents and to identifying neuroanatomical correlates associated
with them. The second objective is to develop, validate and deploy technologies and services for health and
autonomy, innovative in terms of (i) the development of integrated, multimodal, embedded and interactive
physical and/or physiological sensors and actuators and (ii) the assessment, substitution, compensation and
assistance of functional deficits resulting from normal aging, pathologies or accidents. Our work also includes
activities of valorisation of R&D results and technology transfer.
84
First Name Chen-Hsiang
Last Name YEANG
Laboratory Institute of Statistical Science, Academia Sinica
Address 128 Academia Road, Section 2, Nankang, Taipei, Taiwan
Tel +886-2-2783-5611-310
E.mail chyeang@stat.sinica.edu.tw
URL http://www.stat.sinica.edu.tw/chyeang/
Session field Social Sciences/Humanities
Research Field Computational biology, social network analysis
1. Cancer genomics: integrative analysis of cancer genomic data, rational design of combinatorial treatments
of cancer.
2. Molecular evolution: coevolutionary analysis of biomolecular sequences, reconstruction of the evolutionary
history of biomolecular networks, evolution of cis-regulatory elements and gene regulatory networks.
3. Social network analysis: detection of network motifs in large-scale networks, topological characterization
of large-scale networks.
[1] D.H. Chen, Y.F. Chang, B.Y. Liao, and C.H. Yeang. “Functional characterization of motif sequences under
purifying selection”, Nucleic Acids Research 41(4):2105-2120, 2013.
[2] S. Suen, H.S. Lu, C.H. Yeang. Evolution of domain architectures and catalytic functions of enzymes in metabolic systems. Genome Biology & Evolution 4(9):852-869, 2012.
[3] R.A. Beckman, G.S. Schemmann, C.H. Yeang. Impact of genetic dynamics and single-cell heterogeneity on
development of nonstandard personalized medicine strategies for cancer. Proceedings, National Academy of
Science, U.S.A. 109(36):14586-14591, 2012
[4] C.H. Yeang, L.C. Huang, W.C. Liu. Recurrent structural motifs reflect characteristics of distinct networks.
Proceedings, The 2012 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining (ASONAM), Istanbul, Turkey, 2012.
S.D. Li, T. Tagami, Y.F. Ho, and C.H. Yeang. Deciphering causal and statistical relations of molecular aberrations
and gene expressions in NCI-60 cell lines. BMC Systems Biology 5:186, 2011.
[5] C.H. Yeang, F. McCormick, A. Levine. Combinatorial patterns of somatic gene mutations in cancer. The
FASEB Journal 22:2605-2622, 2008.
85
Poster Title Recurrent structural motifs reflect characteristics of distinct networks
Poster Abstract In large-scale networks, certain topological patterns may occur more frequently than ex-
pected from a null model that preserves global and local properties. These network motifs are the building
blocks of large-scale networks and may confer functional/mechanistic implications of their underlying processes. Despite active investigations in systems biology, network motifs are less explored in social network
studies. In this work, we modified and improved the method from Milo et al. 2002 to detect significantly
enriched motifs in both directed and undirected networks. We applied this method to identify 3-node and
4-node motifs from the datasets of 18 networks covering social and biological arenas. In undirected networks,
triangles are enriched in almost all datasets, suggesting the prevalence of transitivity in diverse networks.
However, 4-node structures lacking transitivity — diamonds and stars — are also enriched in the majority of
undirected networks. In directed networks, variations of feed-forward loops are over-represented in the networks of web document and political weblog hyperlinks as well as neuronal connections. In contrast, food web
is enriched with unidirectional motifs with distinct trophic levels. These results reveal the nature of distinct
types of networks and invite further explorations on the relations of network structures and types of relations.
86
ANNEXES
87
Le Relais de Margaux
Hôtel
Restaurants
Spa
Balnéothérapie
Golf 18 trous
Journées d’étude
Banquets
Séminaires
Located alongside the Gironde set in 55 hectares of land in the heartland of the famous Medoc wine country, the
"Relais de Margaux Meeting & Resort Luxury **** Hotel " is only 40 minutes from Bordeaux city center and the
Merignac International Airport at Bordeaux.
The “Relais de Margaux” is an ideal holiday resort to discover this beautiful region, visit prestigious wine castles,
discover oenological and to spend a few days of relaxation. Here wine, country and sports activities harmonize
wonderfully well.
100 rooms, all comfortable, spacious (30 to 70 m²), quiet and decorated in a
cosy Bordeaux and British style (air-conditioning, direct telephone, wifi, mini-bar,
satellite television, safety box, complete bathroom with hair-dryer).
Buffet Breakfast in the restaurant « L’Ile Vincent »
Lunch or Dinner in the « Brasserie du Lac ». Saison menu and Region menu
between 19€ to 38€ (Foie gras of duck, Rib steak « Béarnaise » sauce, shallot
and chips, Gourmet coffees)
Piano bar, lounge and terrace for drinks, apéritifs and liqueurs.
11 private rooms avaible for family events or professional meeting.
Spa Les Bains de Margaux accessible at 09.00 a.m until 20.00 p.m and we
propose you a range of treatement between 09:30 am and 6:00 pm. Heated
swiming pool with jets, sauna, turkich bath, fitness room and relax room are
avaibled as well.
89
LE RELAIS DE MARGAUX
ACCES MAP TO « LE RELAIS DE MARGAUX »
At 30 minutes from Bordeaux and 40 minutes from Bordeaux city centre.
At 45 minutes from Bordeaux St Jean (TGV Train Station).
• At 30 minutes from the airport of Bordeaux-Mérignac. (Take the motorway, direction PARIS)
• By motorway, take the exit 7, direction "Le Bouscat, Eysines Le Vigean, (I) Médoc "
• Follow the signs "(I) Médoc, Eysines Le Vigean ", then "Blanquefort", - "Macau" - "Labarde" "Pauillac" by the departmental road "D2".
• Pass the village Macau, Labarde, and Cantenac and then you will arrive at Margaux.
• Pass also the village Margaux following the Departemental 2, at the exit of the village you turn immediately to the right at the big sign "Relais de Margaux"
From here, you will cover 2.5 Km through the middle of the vineyard until the RELAIS DE MARGAUX.
90
List of past topics
Maquette, numérisation et mise en page : Bernard Dupuis - Secteur de l'Imprimé du Siège Campus Gérard-Mégie - CNRS
Physical sciences
Photonics (FTFoS 08)
Bio inspired Physics (FTFoS 09)
How far can we « see » in the universe (FTFoS 10)
Metamaterials / Plasmonics (FTFoS 11)
Self organization (FTFoS 12)
Arrow of time and non-equilibrium thermodynamics (FTFoS 13)
Applied Sciences
New sources of energy (FTFoS 08)
Mind and brain reading (FTFoS 09)
Super-resolution microscopy (FTFoS 10)
Green chemistry renewable resources breed (FTFoS 11)
Lab on a chip and microfluidics (FTFoS 12)
Disaster prevention/prediction (FTFoS 13)
Life sciences
New approaches for the study of human diseases (FTFoS 08)
Stress and aging (FTFoS 09)
Biological complexity (FTFoS 10)
Synthetic biology & Emergence (FTFoS 11)
Epigenetics (FTFoS 12)
Ecology, biodiversity and evolution (FTFoS 13)
Social Sciences / Humanities
Science and social values (FTFoS 08)
The geopolitics of values (FTFoS 09)
Risk (FTFoS 10)
Trust (FTFoS 11)
The Science of happiness (FTFoS 12)
Social network: quantitative analysis, modeling and its impact (FTFoS 13)
91

FTFoS Symposium

Transcription

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