effect of slimming product - Perpustakaan Negara Malaysia
Transcription
effect of slimming product - Perpustakaan Negara Malaysia
EFFECT OF SLIMMING PRODUCT BAHAGIAN PAKAR MAKLUMAT PERPUSTAKAAN NEGARA MALAYSIA SOURCES 3. http://w\V\v. consuI1]~lab"-£9JTI/Lecal1s. aSfl S. http://nutreL litmania cOl.n/arti~le htm) 6. http://wwwwomanhtcornlsideeffects.ofdietpills.htm 12. httpl/216.23 9.3 5~lQD6;Q<ll.c;h?g=cacbeNOM~?H90H14C :w .. .lanorpats.pdf+slimm ing:f12.iJl-"+&bl= en&ie=UJF~ ConsumerLab.colll- Weight Loss, Slimming, and Diabetes-Management Supplements (Chromium, CLA, an .. Page 3 of4 LonsumerLaO.com purcnasea a IOta I or '115 supplements: I LLA procucts, I chromium products, 2 pyruvate products, and 2 combination products (one with pyruvate and chromium and the other containing chromium, Garcinia cambogia, CLA, L-carnitine and other ingredients) (see How Product§ were Qf;!Elc!EldJ. One of the pyruvate products failed to pass the review because its labeling did not clearly indicate the amount of pyruvate in the product and was potentially misleading. The product name included the words "Pyruvate 1000" but the ingredients indicated that each tablet, in fact, had 1 ,000 mg of a pyruvate "complex" - meaning that pyruvate accounted for an unspecified percentage of the 1,000 mg amount. In fact, testing showed the product to contain only 240 mg of pyruvate per tablet - less than one-quarter of what one might have expected. Another pyruvate product also failed to pass the review, because it contained less than 85% of the claimed amount of pyruvate. Consequently, there were no pyruvate-only products to pass this review - although one pyruvate-chromium combination product did pass. One chromium product failed because it had less than 5% of its claimed amount. Such a reduction in chromium should be of concern to anyone relying on the product for its potential effect on insulin and blood sugar levels. Another chromium product met its claim for chromium, but was found to contain chromium (VI) - the form of chromium associated with toxicity and potential carcinogenicity. Although only a very small amount was present, chromium (VI) is an undesirable contaminant. Ironically, the makers of this product seemed aware of the importance of the different forms of chromium, as this product stated on its label that it contained the "Trivalent" (safe) form of chromium. In total, 14 of the 18 products selected to be evaluated passed this review. All products passed the disintegration testing - which applied only to tablet forms. See Testing MethQcJ§clrlcJPClS§ing$COrf; for more information about the testing and criteria. Products That Passed Testing: Listed alphabetically below by name are the examples of some of the products that passed ConsumerLab.com's independent testing of dietary supplements containing chromium, CLA, and/or pyruvate. Also shown are the claimed concentrations of these ingredients. The full list of ingredients is available for h d t b li ki th r k t th d f it ea pro uc Jy c IC mq on e In a e en a I s row. CONSUMERLAB.COM APPROVED QUALITY CHROMIUM, CLA, AND/OR PYRUVATE PRODUCTS Click on .Ii for additional information on the product Product Name ManufacturerlDistributor Full List of and Labeled Amount of Ingredients from Label Ingredient per Pill [Click below] I IChromium Products: Puritan's Pride® Chromium Picolinate 200 mcg (200 mcg) Mfd. By Puritan's Pride, Inc. FulllngrediElnts Mfd. By Vitamin World, Ellil IngmcJii:)nts Vitamin World® Naturally inspired" Yeast Free Chromium Picolinate 200 mcg Dietary Supplement (200 mcg) Inc. I CLA Products: CLA 1000 mg Conjugated Linoleic Acid (CLA) Dietary Supplement (720820 mg) A.Nature Made® I I Mfd. By Vitamin World, Inc. II FllJLI ngCEldii:)nt§ II I 8/19/01 • Conslll1lcrLabcul11 - Loss, Slimming, and Diabetes-Management Supplements (Chromium, CLA, an. Page 1 of 4 Product Review: Weight Loss, Slimminq, and DiabetesManagement Supplements (Chromium, eLA, and Pyruvate) What It Is: Many ingredients have been touted for weight loss and/or slimming (increasing the proportion of lean body mass). A number of these have also been used in the treatment of diabetes as they may positively impact the levels of sugar and insulin in the blood. These ingredients include ephedra (an herbal product also known as ma huang and which contains ephedrine), CH ROM I. U M hydroxycitric acid (HCA) from the fruit Garcinia cambogia, conjugated linoleic acid (CLA) (a Be Sure !t'$ CL!<pproved polyunsaturated fatty acid found naturally in milk and meat fats and produced from safflower and sunflower oils), the essential mineral chromium (naturally found in animals, plants, and soil), as well as pyruvate and Lcarnitine (both of which are found and made in our bodies). What It Does: The amount of evidence supporting the various weight loss, slimming, and diabetes-management ingredients Be Sur., It's (I.. .Appn:.wod varies greatly, and, for many, is not very strong. There are also safety concerns for some regarding their use. Below is a summary of information about several of the most popular ingredients used for weight loss or slimming (see Consumer'I'ips ?' for more information specifically about the forms, dosage, and safety for chromium, CLA, and pyruvate): PYRUVATE Summary of Evidence for Popular Weight Loss, Slimming, and Diab'Dt~"Sl~],<lPfi9l$'I:'tnj,npro'j/o . Ingredients t I Iingredient Name Purported Use Evidence Safety Chromium Improving blood May be effective Trivalent form is sugar control in for diabetes and generally people with type mildly impaired considered safe " diabetes, or glucose when taken at a more mildly tolerance, but dose of 200mcg impaired glucose more research daily or less; tolerance. needed. however, long \. Assisting weight One reasonably term safety loss and large study found testing has not improving body it effective for been performed. composition weight loss; most Hexavalent form (faUmuscle ratio). other studies may be toxic and failed to find should not be evidence of found in benefit for weight supplements loss or body (see below). composition. CLA (Conjugated Linoleic Acid) Slimming / Small studies are Generally safe. leanness (but not suggestive of weight loss). May efficacy. More Cons1ll11crLab.com - Weight Loss, Slimming, and Diabetes-Management Supplements (Chromium, CLA, an .. Page 2 of 4 research I also Improve needed. I I I insulin levels in diabetics. Ephedra May aid weight loss by suppressing appetite. Shown effective when combined with caffeine. May cause high blood pressure, stroke and serious heart problems particularly if used with caffeine. Canada asked for a recall of ephedra products except in very low doses. Hydroxycitric Acid (HCA)/ Garcinia cambogia Weight loss by interfering with fat metabolism or appetite suppression. Studies have shown mixed results. Generally safe. L-Carnitine Inhibition of obesity Little evidence of effect on obesity, (although proven useful in some cardiac diseases). Generally safe. Pyruvate and dihydroxyacetone - DHA. Also called DHAP when pyruvate and DHA are combined. May have modest effect on weight lossparticularly fat loss. Small studies are suggestive of efficacy. More research needed. No serious side effects when taken orally. Vitamin C (See CL's Vitamin ~ ProQLJ~tBElvLew) May help with weight loss in significantly overweight individuals Small studies are suggestive of efficacy. More research needed. Safe, though in high doses (1,000 mg), may cause diarrhea. Based on the clinical evidence supporting their potential benefits and risks in weight loss, slimming and/or diabetes, ConsumerLab.com focused its testing on products containing the following ingredients: chromium, CLA, and/or pyruvate. In addition to the uses indicated above, these ingredients have other potential actions and uses. There is mixed clinical evidence that chromium may help lower cholesterol. CLA, in animal studies, has shown a cholesterollowering and cancer inhibition effect. Pyruvate may enhance exercise endurance when used in conjunction with DHA and it may also have a cholesterol-lowering and blood pressure-lowering effect. Quality Concerns and What CL Tested For: The chromium that our bodies require is called trivalent chromium or chromium (III). Another type, called hexavalent chromium (VI), does not occur in significant amounts naturally but can be formed as a by-product of industry. Ingesting large amounts of chromium (VI) can cause stomach upsets and ulcers, convulsions, kidney and liver damage, and even death. Chromium (VI) is also a known carcinogen (particularly when airborne) and is, for example, the form of chromium implicated as causing cancers in the movie Erin Brokavich. While it should not normally be found in chromium supplements, it has been known to occur as a contaminant. Consequently, all of the products claiming to contain chromium were also tested for levels of chromium (VI). Neither the FDA nor any other federal or state agency routinely tests supplements for quality prior to sale. Consequently, ConsumerLab.com tested the CLA and pyruvate products, as wei' as the chromium products, to confirm the identity and amount of these respective ingredients. All tablet and caplet products were also tested for their ability to disintegrate properly so as to be available for absorption in the body. What CL Found: RI19/01 lJutriWE13 lVL1laysia • Page 1 orz HealthYE:~tLtlg I Y\[elgbtlssues I Fit & Trim I £@gn--9lJ~Y1k_LacJacling I Diet & Diseases I Food Laws About NSM Mission of f'JutriWEB Rules of NSM (I By-Laws ofNSM (:I Council Member (:I Publications (I (I C) FAQs Application FQrQ1 I\lutrition Tools Food Pyramid '::1 BMI Calculator (:I CaioriesBlJIQIT (I (:I o Date: Tuesday, July 09 @ 12: 38: 32 MYT Heart Hate Monitor featured Content 3,«1 MIAlll ((ijlGltm C>fmETfnCS ~y IT is a f/ab-bergasting fact. One in every five adult Malaysians is either overw. sudden spurt in the incidence of obesity may well lend it the infamous distinct century"s leading national health problem. Obesity is simply an excess of body fat. It is a contributing cause of many pre maladies. It increases the body"s resistance to insulin and susceptibility to inf at a higher risk for developing coronary artery disease, diabetes, gallbladder ( pressure, kidney problem and stroke. Statistics indicate that obesity is a high-risk national malaise. Around 7.9 per nation "s obese adult population are women and 4.7 per cent are men. It is a not spared the armed forces personnel for many are spotted on duty with big jutting out from behind the shrubs and bridge columns along the highways an warning of a speed trap. This may well be construed as, a sign of developmer infectious diseases to lifestyle diseases implies a certain level of material afflu preventable ailments were seen as a rich man"s disease and common only to countries. But today, the situation is reversed. The prevalence of non-communicable diseases is rapidly rising in developing ( to the World Health Organisation, some 79 per cent of the deaths due to such occurred in the developing countries and, these countries would see over 100 coronary deaths during 1990-2020. Apart from hereditary factors and endocti chief culprit of obesity is a combination of unhealthy eating habits and a sede: Statistics show that every year globally, around two million deaths are attribu inactivity. Most people indulge in static mental exercise such as surfing the in: the television and reading - in Malaysia"s case, even the latter is not pursue: unflattering impression of a nation of corpulent and mentally-lazy slobs. The f and the carbohydrate-laden twominute noodles as convenient substitutes for also contribute to weight gain. , . Clearly, it is imperative that the Government prioritises disease prevention an promotion. The Health Ministry"s Healthy Lifestyle campaign must be cornplei measures to promote physical activity since factors such as environment, spo amenities influenced people"s inclination in this direction. There must be ratic measures such as the creation of protected cyclists" lane would aspire people Obesity clinics should be set up in all public hospitals. If Malaysians are getting fatter, it does not mean they have stopped trying to Businesses have cottoned on to the demands for a slim, trim figure by churnir products from the frontiers of alternative medicine. And since these products consuming approvals from the drug control authorities, they score hugely ove Thus, the market is inundated by slimming pills and salons. ~. nutriWEB Malaysia Supported by ut« Malaysia Page 2 of2 Alas, there is no quick fix for obesity. Not all the contents of slimming pills cal vouched for. Those with banned substances are lethal, causing death or dame organs. Diets such as the high-protein diet, grapefruit diet and cabbage soup about temporary weight loss, but some is likely to be simple water loss. Wher a wide variety of whole foods or prescribes mainly one food as the miracle die eventually one"s health is going to suffer. The only intelligent way to lose wei is through a well-balanced diet, exercise and prescribed drugs. v •.• , '", .'; '" I .• ~." f,j .,.".~ l ' 1'( All individuals have the weapon to fight obesity: living a healthy lifestyle. Ind: choices have never been more important in determining the outcome of a nat in eliminating a national image of indolent fatsos. - New Straits Times (7-Juf-2002) Copyright © 2000-2002 Nutrition Society of r"1alaysia. Website jointly deveioped by MIMCj:Q..JiQil Bhd and Versacomm Sdn Bhd. Nutrition Society Malaysia (NSM), c/o Division of Human Nutrition, Institute for Medical Research, 50588 Kuala Lumpur, Malaysia Any comments, suggestions, or questions? ~ili£U'our feecU;S'sk here! ConsumerLab.com - Weight Loss, Slimming, and Diabetes-Management Supplements (Chromium, CLA, an .. Page 4 of4 -- "--------- COOjLI9CltGd linoleic Aci(j~QQrngQietary SURRls2ment (50Q Il1c;g ) NOW®CLA Conjugated Linoleic Acid 1000 mg-70% CLA Dietary Supplement (700 mg) Nutritional Products FLJD In g rElcJiEl nls Mfd. By Now Foods I [Pyruvate Products: II I None passed I Combination Products: Nutrilite® Trim Advantage ™ Weight Management Support Pack (Chromium 1 00 meg/strip; CLA 300 mg/strip) II I I DisL By Nutrilite ELJ IL) I]g [Gc:JiElot$ Unless otherwise noted, information about the products listed above is based on the samples purchased by ConsumerLab.com for this Product Review. Manufacturers may change product ingredients and information at any time, so be sure to check labels carefully when evaluating the products you use or buy. If a product's ingredients differ from what is listed above, it may not necessarily be of the same quality as what was tested. It also cannot be assumed that other products from a Manufacturer or Distributor listed above are of equal quality to those listed. Copyright Consurnerl.ab.com, LLC, 2002. All rights reserved. Not to be reproduced, excerpted, linked to, or cited in any fashion without the express written permission of ConsumerLab.com LLC. Want to see more? For a complete list of CL Quality Approved Products that passed this review, as well as ConsumerLab.com's ConsumerTips ™ for buying and using such products, please click below on the "Log In" button if you are already a subscriber or the "Subscribe" button to learn how to subscribe. Subscribers can also access the Natural Products Encyclopedia and the archive of Recalls and Warnings on this site. $LJQ$.c;rJtJe I horne I logIn I mY.ilc;_c;@Qt I prjy<:).c;YJ2QU.Qy !gQOJiliQfyJEl$ire§.LJLl.§ I DgiLJIClLpLQc:J.1,l c;i§i2D_C;Y.QJQW2c:JISl I rEJ.QilU~~9rnLng § search ,thi$..site I Q.QQJJ.LI,l§ I the cI seal I testing programs tech nical &oth e r .. LEl PQ rt § I n.G WS I j Qi nJ[GG nGvv§IGttG[ Ic;QDt<:)c;tl,l$/hGlp © 2002 ConsumerLab.com, LLC. __ 1r""conSUl11crLab.c0ll1 - independent tests of herbal, vitamin, and mineral supplements Page 1 of2 Be Sure fI 's CL Approved) Recalls and Warnings From time to time, ConsumerLab.com learns of recalls, warnings, or other alerts relating to vitamin, mineral, herbal, and other dietary supplements, as well as other nutrition products. Subscribers can access any of these reports, while nonsubscribers can view the latest posting and the headlines of earlier reports. This new service began January 1, 2002. Latest Recall andW:;:,nlinn FDA Warns Public About Chinese Diet Pills Containing Fenfiuramine (Date Posted 8/15/2002) On August 13, the U.S. FDA alerted the public about Chinese weight-loss products, Chaso (Jianfei) Diet Capsules and Chaso Genpi, because they pose a potential public health risk. The agency is alerting the public to this health risk because several people in Japan have become ill, and some have died, after consuming these diet products. "FDA is taking this action as a precautionary measure to help assure that people are not exposed to this potentially dangerous product," said Dr. Lester M. Crawford, FDA Deputy Commissioner. AcJvcnliscrlkmt Products of this type are often sold in small urban markets as alternatives to Western medicine. In 2001, FDA issued a nationwide alert on the recall of thirteen "Treasure of the East" herbal products because of a dangerous ingredient, aristolochic acid, which is toxic to the kidney. The deaths in Japan linked to these Chinese weight-loss products may have resulted from the presence of such active drug ingredients as fenfluramine in the capsules. Fenfluramine and another diet drug, phentermine, were used in combination for weight loss until it was determined that the combination of drugs was linked to valvulopathy, a serious and sometimes fatal heart disease. Fenfluramine and a chemically similar drug, dexfenfluramine, were removed from the market in 1997. Phentermine, when used alone, has not been associated with valvulopathy and remains on the market. FDA has advised its import operations personnel to be on the alert for Chaso , Diet Capsules and Chaso Genpi. The agency is urging consumers not to take these diet pills and to notify their local FDA if the products are found in their area. Archive of Recent Recalls and VV<l.rnin~s • 8E?c;Clllgf] HerPClIPr9cJuc;tsJrQI'DE3otClllicLcabin LJsancJ AbroCld (Posted: 8/9/2002) http·JJwwwcons\lmerhh.comlrecal1s.asp 8/19/01 • ConsumcrLabcom - independent tests of herbal, vitamin, and mineral supplements Page 2 of2 •• Rec9lL91 N atu re' s _\}\/_a y Nett I Q£' rQc:JLic;t J:)1lE2J9b§'lc;LC_o_ nta min a tio n (Posted: 7/1/2002) •• Becall QLDalyvite ligI,Jid MUltiyit~llliD (Posted: 6/30/2002) e CClOClQian\}\/"rning on Use ofSevEln Herbal$upplernElnt::; frollJ E3otanicLi3t:J (Posted: 6/21/2002) eCi3Di3cJian\}\/ClrningonUse of BejaiBowyantan fgrIOfClnts(Posted: 6/20/2002) e Rgc;ClIILJPQatEl for Portagen Iron Fortified Nutrition PoINder (Posted: 5/24/2002) Ultra Slim~Fast with Soyprot§ioQrink::; (Posted: 5/17/2002) <> MorEl Information 5/3/2002) of PC-SPES -ProstatEl SupplgllJElot (Posted: (Posted: 3/25/2002) •• RecCl11 of Multivitamin Unsafej30ttling ForChilcJI§O (Posted: 3/12/2002) ..R§c;i3IIClDd\}\/arning to Stop Use of Prostate Supplements "PC$Pf':S" i3nQ"SPES" (Posted: 3/11/2002) •• Reci3I1QtAdcJitiOl1al Pepsin-containing Dige::;tiv§AicJs (Posted: 2/7/2002) •• Rec;ClIL LJpdi3te for Certain Bar::; -Exce::;sivElVitClrninA (Posted: 1/31/2002) <> Rec;all of Certain Iron (Posted: 1/19/2002) •• B~LalI of P.Jill_"inSQnti3ining [)igc;stivc;_$UP[21(jrnent::; (Posted: 1/18/2002) <>R§callot"Prostatin" Supplement -- Contain::; Aristolochic I\c;icJ (Posted: 1/15/2002) e CClOClQ?RE;quests of (Posted: 1/11/2002) ..Kava (Posted: 1/7/2002) Information from the ConsumerLab.com archive of Recalls and Warnings is available only to current subscribers to ConsumerLab.com. If you are a subscriber, please login now. If you would like to subscribe, please click OE;re. For information about reporting serious reactions and problems with medical products to the U.S. Food and Drug Administration through its MedWatch please go to §jJj;).::;c;rll:J~ I nome I LOgin I mYi3.c1QlJIJt Ipriys1CY.PQJic;y JQQm'ltQrytEl~trEl"'Lllt::; I Ili3JI,Jr?I.PIOcJW;;tSf:2nc;y_c;IQQ§<:Jii.l. 1 rf:2C;ClU~_<l<_\l/ClmLng::; search this site I abQuJ~ I the cl seal I testing programs t§_c;hnic;91!l-,othflLJElPQrts 1 De.IN .. ::;. 1 jQinfreeflElw::;lett§r lc;onti.l.c;Lu::;Jb,§lg © 2002 ConsumerLab.com, LLC. Page 1 Page 1 of2 Slimming pills have recently been seen by some as the easy way to lose weight. However, besid that they have only a limited ability in assisting weight loss these pills have many inherent dange counteract much of this limited usefulness. It is a very human reaction to want to fix a problem fast and when people are overweight, they n an instant remedy. Well, it would be magic if we could sort of book into a "fat transfusion service all those unwanted kgs to other people who need a bit of padding, and then walk out of the treat weighing 20 kg less! Unfortunately, this kind of service is not available, but we still demand fast Consequently a great deal of research is done to find an ideal pill that will help overweight peopl excess weight. Over the years researchers have come up with countless products that are supposed to aid wei either suppressing appetite or increasing metabolism to help burn up fat. Most of these products do what they are supposed to do, or they cause unpleasant and dangerous side effects. Let's have a look at some of the categories of slimming pills and their disadvantages: Slimming pills that contain diuretics stimulate water-loss. If you take a pill that makes you lose s water, your weight will decrease by 1 kg, but the moment you drink liquids, this water will be repl body and your weight will return to normal. Unless prescribed by a physician, diuretics are paten because certain diuretics increase potassium losses along with the water-loss. You need potassi body functions and potassium depletion can lead to muscle weakness, including weakening of t muscle, and mental confusion. Water depletion is also dangerous, particularly in hot countries lik Africa. Slimming pills that contain laxatives stimulate the digestive system and can cause severe diarrh are taking one of these products and find that you are constantly suffering from diarrhoea, then it to stop taking the diet pill. Constant diarrhoea prevents proper absorption of food and you may d dehydration due to water-loss, and vitamin and mineral deficiencies, all of which may have bad health. Harsh laxatives also have the disadvantage that they tend to destroy normal peristalsis (t movement of the bowels). People who take harsh laxatives for long periods, lose the ability to pr stools. Slimming pills that suppress the appetite often contain derivatives which cause unpl effects such as palpitations, dry mouth, insomnia, restlessness and anxiety. Other appetite suppressants contain '" '0', derivatives and are highly addictive. In addit effect tends to wear off if they are taken long periods, so the patient is inclined to take large a doses with ever increasing addiction. also fall into the category of appetite suppressant. Fenfluramines suppress appe interacting with certain receptors in the brain, but the latest research shows that fenfluramines al detrimental effects on health. PPH is a life-threatening disease which causes heart failure and d http://www.weightlosslab.com/new_page_l.htm 8/20/01 Page 2 of2 Ncw P,lgC I have shown that people who take fenfluramines run a 10 to 20 times greater risk of developing P those who do not take these chemicals. In addition, fenfluramines have been linked to brain rece damage, which may not be reversible. But what can people do who are overweight? The most sensible approach to weight-loss is to ea highcarbohydrate, high-fiber diet and do regular exercise (NorwoodJ!I/E!tghLL,.Q~JLP'rQgr§rr1J T will make those kgs drop, slowly, but steadily, and ensure that the lost kgs are not put on again. favor, avoid slimming pills, and use a sensible approach to weight-loss. The results will be 100% without any harmful effects to your health. http://www.weightlosslab.com/newyage_l.htm 8120/01 free health and weight-loss information and advice Page I of3 August Report: The popularity of weight loss drugs and supplements are on the rise, but according to the government's recent guidelines for the treatment for weight loss and obesity, about 55 percent of people in Britain, or 32 million people, are either overweight or obese. Quick-fix diets, pharmaceuticals, and even "natural" weight loss formulations don't promote good eating habits because they are not a life-long plan. "When you talk to me, we're talking the 90-year plan," says Edinburgh-based nutritionist Anne Dubner." You need to establish eating patterns that work longterm, and incorporate foods that allow you to lose, and then maintain, body weight." Dubner, whose specialty is weight loss, found that her clients didn't want to learn anything about diet, they just wanted to take a pill and lose weight. But when they went off the drug they gained the weight back. "I do not recommend weight loss drugs. I'm sure they work, but they are temporary." Dubner believes that if weight loss drugs are used they should be a part of a multidisciplinary approach. "See a dietician, psychiatrist, or psychologist, if necessary." Weight loss drugs can serve as a jump start for an individual who is significantly overweight, or someone who has to lose weight before undergoing surgery. Both Fen-phen and Redux were found to cause damage to heart valves and were taken off the market in 1997. The newly hyped weight loss drug, Meridia, released last April, acts on serotonin and norepinephrine, another brain chemical to make users feel full, like Fen-Phen and Redux, but not in the same way. Researchers at Knoll Pharmaceutical, , who produce Meridia (sibutramine), say Meridia works on two neurotransmitters instead. of just on serotonin. What's coming down the road in the way of weight loss drugs? Orlistat, which will be marketed as Xenical, received the American FDA advisory committee's approval in May 1997, but Hoffmann-La Roche, its manufacturer, has decided to do more analysis before releasing it for final approval. Orlistat is a lipase inhibitor, which means it works on lipase, an intestinal enzyme that breaks down fat. Xenical cuts fat absorption in the intestine by about 30 percent. http://nutrel.litmania.com/article.html 8120101 '~'ec health ,1I1e! weight-loss information and advice Page 2 of3 According to many health foodshop operators, herbal phen-fens in ali forms - from teas to pills are by far the biggest sellers of herbal weight-loss products. And, chemists and experts agree, the reason for their popularity is probably due in part to slick marketing tactics by manufacturers that compare their products to the banned fen-phen prescription drug. The big difference, according to herbal phen-fen marketers, is that unlike the prescription drug, their herbal phenfens are completely safe because they use "natural" ingredients. "Some of the most potent toxins are 'natural' ... even poison is natural ... the word 'natural' does not guarantee safety," says Dr. Kathy Kapica, PhD, RD, associate professor of nutrition and dietetics at Chicago Medical School. And, according to Dr. Kapica, another major problem is that due to the lack of government standards for botanicals and herbs, consumers can't always be sure that the products they are getting are pure, or even contain what the labels say. "It's very scary to think that consumers invest in products that they think will help them when they'll actually be lucky if they don't harm them," adds Dr. Kapica. Most herbal phen-fens contain a mixture of herbs which often include ephedra, St. John's wort, chromium picolinate and others. Some ingredients like ephedra, which is addressed below, can be dangerous when abused, while others, such as St. John's wort and chromium picolinate, show no clinical evidence of being beneficial for weight loss. Ephedra, also known as ma huang, is a strong stimulant found in popular herbal phenfen diet aids. While the efficacy has been well researched and substantiated for relieving nasal congestion and some allergic disorders, Varro E. Tyler, an authority of the medicinal use of herbs, states in his book, The Honest Herbal, that "there is no substantial clinical evidence that [ephedra] is either a safe or effective promoter of weight loss in obese patients." And, ephedra can be very damaging to the body, especially when abused. Its active ingredient is ephedrine, a stimulant that works in the body much the way that adrenaline does in what is known as the "fight or flight" response. The danger is that when taken regularly, your body stays in an unnatural high gear and there is risk for heart palpitations, heart attacks, and strokes: particularly for those with a history of heart disease, hypertension, diabetes, or thyroid disease. To date the American FDA and Centers for Disease Control Prevention have received more than 900 complaints about products containing ephedrine, including 17 deaths. The FDA has plans to regulate ephedrine levels in dietary supplements in the future. Many herbal phen-fen combinations with ephedra contain St. John's wort as well. Manufacturers of diet supplements containing St. John's wort claim it may increase the production of the brain chemical serotonin, possibly having a positive influence on mental wellness, which could help suppress overeating that may be linked to depression. St. John's wort has been one of the most scientifically researched medicinal herbs in history. Many clinical trials in Britain and abroad using standardized St. John's wort preparations have confirmed its safety and effectiveness in treating depression. However, there is no clinical evidence to substantiate that St. John's wort has weight 1055 benefits. Marketers of this popular diet supplement tout its ability to "trap" and get rid of dietary fat and cholesterol. The theory is that when taken regularly, chitosan-a non-digestible dietary fiber-will decrease the absorption of fats and carry them, along with their calories, right out of the body. While there have been some promising studies that show chitosan to have a cholesterol-lowering effect in animals, there has been no such evidence in humans. "There is absolutely no research indicating that chitosan is effective for weight loss," says Dr. Kapica. "It has never been tested for weight 1055, or in humans at all." In fact, Dr. Kapica says that Chitosan has the potential to be harmful due to the fact that it binds fat soluble vitamins, which could result in deficiencies and set in motion, . other harmful effects. And, while limited research has shown chitosan may help lower cholesterol in animals, Dr. Kapica says Chitosan isn't even at a point where it can be recommended for that. The bottomline is that we just don't know enough about chitosan and the potential dangers from taking it. Therefore, she says, consumers would be wise to stay away. None of the weight 1055 drugs on the market now, or any that might be available in the future, are going to solve the problem of excess weight. And serious health effects were found with the drugs that have been removed from the market. Each year Britons spend billions of pounds in the hopes of finding the magic pill(s) for weight loss. Accurate figures are hard to come by in the UK, but in the States, according http://nutrel.litmania.com/article.html 8/20101 ~~'C' Free health and weight-loss information and advice Page 3 of 3 to the National Council Against Health Fraud, a whopping $8.9 million are spent annually on vitamins and dietary supplements alone. And, because vitamins, herbs and other supplements are not officially regulated by the Department of Health, consumers are often unaware of the proper dosage amounts, efficacy and product safety. Then, add to that the fact that an incredible amount of diet supplements are introduced each year, making it Virtually impossible for government officials to keep up. There have been a number of cases recently of the Department of Health withdrawing much-hyped slimming pills from the market, which has shaken many people's confidence in appetite suppressants. In April 2000 the government banned several pills because trials had shown they didn't "help people lose weight effectively" and even "caused lung and heart problems in some patients." The supplements removed were Duromine (phentermine), Ionarnin (phentermine), Diethylpropion (amfepramone), Tenuate Dospan (dexfenfluramine), and Ponderax (fenfluramine). When checking out weight loss supplements, read the claims and literature carefully. One product manufacturer, after touting its product's effectiveness, also encouraged users to exercise for 20 to 60 minutes five to seven days a week; eat three low-fat, balanced meals and two snacks every day; eat at least two servings of fruit and three servings of vegetable each day; drink six to eight glasses of water every day; limit or stop drinking alcohol; stop eating two to three hours before bedtime; reach for the walking shoes before reaching for the refrigerator ... etc. This sounds very much like the Department of Health's Dietary Guidelines for Healthy Living, which remarkably when followed, generally result in a healthy weight and best of all, here they are for fl-ee. Department of Health Dietary Guidelines Eat a variety of foods Balance the foods you eat with physical activity-maintain or improve your weight e Choose a diet with plenty of grain products, vegetables, and fruits e Choose a diet low in fat, saturated fat, and cholesterol " Choose a diet moderate in sugars •• Choose a diet moderate in salt and sodium " If you drink alcoholic beverages, do so in moderation e e "Weight loss should be managed long term and include modification of your diet, more exercise and other important lifestyle changes." Professor Liam Donaldson, Chief Medical Officer, Department of Health, February 2002. © 1 August, 2001; Nadeem Azam, Bradford University BMLCpJC:LJ.@t Q[ I http://nutrel.litman ia.com/article.html 8/20/01 Page 1 of 4 Side effects of diet pills Beauty Who's the hottest? Slimming pills may Earning Money seem like a quick and easy way to lose weight, but they do have side effects. Sometimes, the side effects can be fatal. Entertainment and (@ Prince William \' Ben Affleck \' Josh Hartnett \' Hayden Christensen Celebrity Heard of Slim 10? Women in Singapore have been using the slimming pills for quite a while, before it came the notice of the authorities that Slim 10 contains a drug called \' Tobey Maguire \' Orlando Bloom \' Matt Damon fenfluramine. 3 cases Health of liver damage due to SIim1 O. Of these, the most well known victim in Singapore, was local celebrity Andrea De Cruz. Lifestyle Her doctor suspects she had been taking the pills for 2 to 4 months when the liver damage was apparent. Her sister noticed that Andrea's had a \' Brad Pitt \' David Beckham \' Jet Li \' Jackie Chan \' Will Smith yellowish tinge. Love and Romance SUbsequently, Andrea started having fever and slipped in and out of consciousness. Motherhood ----_._--------_._. \' Denzel Washington r Russel Crowe She was on the brink death. It was literally \' love that saved her. George Clooney She needed a liver to replace her failing one. \' http://www.womanht.com/side_effects_oCdiet.-J)iIls.htm \ . 8/20/01 • Side effects of diet pi lls Page :2 of 4 Her fiance, Pierre Png, Sean Bean also a local celebrity took the risk. He donated almost half his (" Pierce Brosnan liver to her. That saved her life. Both are recovering now, but (" Harrison Ford she would be on medication for the rest of her life. (' Mel Gibson Why is he the hottest? Merida has been linked to 29 deaths and several side effects. "The department of Health in Britain reports that two patients taking the anti-obesity drug ===c2...L Reductil (Meridia) in Britain have died and more than 200 others have had suspected Hettie I-'--~adverse reactions. " Tobey Maguire ~h Hartnett For one thing, it increases heart rate Brad Pitt and blood pressure. Prince William Hayden Christensen Seizures were reported Ben Affleck in <0.1 % of patients --> using it. Orlando Bloom George Clooney Other side effects Mel Gibson include anorexia, David Beckham insomnia, abdominal pain .. Matt Damon Russel Crowe Will Smith HarrisonFord Pierce Brosnan Phenylpropanolamine (PPA) is found in many _. Jet Li slimming pills or diet pills. Sean Bean FDA has banned Over the Counter sales of anything Denzel Washington Jackie Chan containing Phenylpropanolamine (PPA) for safety reasons. Votes 73 59 40 38 35 25 22 20 14 12 12 10 10 9 8 8 7 6 2 \/otes This drug helps you control a huge appetite. Thus, it was used as a slimming aid. Unfortunately, the side effects of the drug can be fatal. Examples of such side effects are the development defects in their heart valves, primary http://www.womanht.com/side_effects_oCdiet_pills.htm 8/20/01 Side effects of diet pills Page 3 of 4 pulmonary hypertension which is a lung condition that can be fatal, among other things, These are fibre supplements that bind to some of the fat that is not digested yet They make the fat indigestible and allow the fat to pass through the system without being accumulated in the body, Side effects include uncontrolled bowel movements, oily discharge, oil spotting and constant stomach discomfort If you plan to use slimming pills to lose weight, please don't If you have friends who are using slimming pills Please email this article to them. A safer way to lose weight is through proper [ill Tobey t',/lal]uire [ill E:rad D F'rince \,'i/illiarn Pitt EJj] Orlando fill r',/lel E:loorn Gib::;; 0 n [ill t',/latt Dar-non EJj] 'V\iill Srnith [ill E:eckham till Harrisonford fit .let !'!ill :3ean E:ean [ill.Jackie Chan C;eor'l~le C:loc1ney D Da',/id Li [ill Denzel \I'/ashington Try working out. Too broke, busy or embarassed to get a gym membership? Try working out al\1home. Another alternative for lazy girls is To get in shape, try exercise instead, Run slowly for 30 minutes every day on the tread mill like the one from for the next few-months and see the results yourself http://www.womanht.com/side_effects_oCdiet_pills.htm 8/20/01 Slimming pills bring fat profits - APRIL 30, 2002 Page] 0[2 Apr 30,2002 Slimrninq pills ring fat profits Up to 100 fat burner drugs are being developed by US pharmaceutical companies in a mad rush to reap the billions that will come to the next firm that hits on that allelusive formula to fight obesity WASHINGTON - Obesity has been identified as the 'largest future market' for pharmaceutical companies racing to develop tile next prescription diet drug. Up to 100 obesity medications are in the early stages of development, insiders say. Some are designed to bum calories; others tinker with brain chemistry to control appetite; still others promote a feeling of fullness in other ways. Some may one day be used to treat people who have only 5 kg or 10 kg to lose. Most of the drugs in the pipeline will probably never make it to the market, and the few that look the most promising are still at least two years away from being prescribed to obese Americans. But for drug makers, it's worth the gamble: The company that comes up with the next really safe and effective diet drug will probably hit pay dirt, possibly making billions of dollars, obesity researchers say. In the United States alone, potential patients include 54 million people who are obese, which is roughly 14 kg over a healthy weight. Add to that a growing number of overweight children and an increasing number of heavyset people around the world. 'We think obesity represents what is unquestionably the largest future market for pharmaceuticals,' said Mr John Maraganore, senior vice-president of strategic product development for Millenium Pharmaceuticals, which is working with Abbott Laboratories to develop obesity and diabetes drugs. There are only a few prescription drugs now used to treat obesity, including Meridia, which works on brain chemicals to control appetite, and Xenical, which blocks some fat from being absorbed by the body. However, the cost of developing a prescription medication is estimated at US$802 million (S$1.45 billion), according to the Tufts University Centre for the Study of Drug Development. Marketing diet drugs is also full of pitfalls. Some people are reluctant to take them because of the withdrawal of two diet drugs from the market fenfluramine and dexfenfluramine (Redux) - in September 1997 because of concern that they could be linked to heart-valve problems. Furthermore, obesity drugs often are not covered by insurance, and some people expect miracles from these medications. But pharmaceutical companies are betting that the public's attitude towards obesity medications will change. http://straitstimes.asial.com.sg/health/story/0,3324,117116,00.html 8/20101 , "'~_.::1~~ ,. r Slimming pills bring fat profits - APRIL 30, 2002 Page 2 of2 Mr Terry Opgenorth, of Abbott Laboratories, compares today's attitude towards obesity drugs to past views on blood pressure and cholesterol drugs. People once thought blood pressure and cholesterol should be controlled with diet and exercise not medication, he said. ' r~r Louis Aronne, director of weight programmes at the Weill-Cornell Medical Centre in New York, said doctors might one day treat people who had 5 to 10 kg to lose in the hope of keeping them from becoming obese. Many experts caution that no drug wili ever be a panacea, and that nothing beats diet and exercise for controlling weight. Consumer advocate Sidney Wolfe, director of the Public Citizen's Health Research Group, is sceptical of diet pills. The group is asking for a ban on Meridia, which it associates with 29 deaths. Abbott Laboratories maintains that Meridia is safe and that experts cannot confirm whether people died solely because of the medication. Mr" Thomas Wadden, director of the Weight and Eating Disorders Programme at the University of Pennsylvania School of Medicine, says drugs have an important place but are not the only answer to the obesity epidemic. Drugs would probably end up being most beneficial for people who had a genetic propensity to being overweight, he said, adding: 'Even the best drugs in the world are going to be no match for billion-dollar ad campaigns that encourage people to super-size their bur-gers and fries. People don't realise they are super-slzlno themselves,' --USA Today <font face='Verdana, Arial, Helvetica, sans-serif size="- I http://straitstimes.asial.com.sg/health/story/0,3324,117116,00.html 8/20/01 Asiawcck.cOIll I Health: Looking for Trouble 112/24/99 Magazine Archive 2001 1999 1997 1995 Special Sites Besl Universities 1\11$;\ PI'Ogril1l1 Other News roo R TUNj:SOlJ} FORTUNE-----_._-_.~ China MONEY.com ..... _--_ .. _--- ---- ~._ .. 1\0 L._c()111 I::m latest Asiaweek relurn HOll),€, Search the Asiaweek site tor vour ChOSCll topic tile Asiaweek for l11oreTi'i3r16 Asiavveek covers stories • Page 1 of2 By JIM ALCIE P",nn!(nk without having to work at it are about as has Most know their chances of ephemeral never stopped anyone from buying into of a as a free lunch. That, the fantasy of super'-duper diet pill How could being mode! slim with they resist? In 1'1 have been purchasinq slimrninq pills, India. girls as younq usually over the counter But the dream solutions come Kong, the danqers were starkly outlined when an collapsed and died on Dec 8 She had been on for a year three different kinds Ten days earlier, ail inquest found that another woman dieel From taking slimming pills containing a harmful ClnoRtitR ,:"'nl'~",'c:"'nt Just as marketing is the name of ~1dme. so it is part of the problem, VVe have all tile ads BUill calories while you use a natural formula to block fat-absorption. products are often solei as herbal concoctions or dietarv under that amorphous heading - health' This means pills can turn up on store shelves without the more rigorous standards set for pharmaceuticals Consider tile compound c:/lracteci from the Chinese herb, mahuang, pills which claim to burn fat by rate The extract certainly heart rate but it can also cause blood vessels constrict, blood pressure It can dampen and increase alertness, but, like caffeine, call insomnia and the jitters In the US, the Food and Drug Administration decided there was insufficient evidence of danger to limit the amount used, But ephedracontaining products still worry some experts because of reported links to seizures, strokes and heart attacks. A recent report in the Journal of l'.Jeurology, Neurosurgery and Psychiatry also implicates mahuang extract, taken as "energy supplements," in strokes. Not surprisingly, the Hong deaths have prompted calls for stricter laws on health products. (A survey by the local consumer council found that 85% of ads for health foods and thel'apies contained doubtful, even hazardous, clairns.) peg,pie Director Ann Hui's extraordinary coup Cinema From Thailand, a haunting blockbuster Health fhetlazards of being tall and thin Newsmakers Jailed, no bail: Lee Wenho ~ ASiAWEEK Health: A Cut Above the Rest Why more men are turning to plastic surgeons Health: This Bean isno haS-been Is-soya the next wonderfood? Health: AIDS Explosion Of course, diet drugs obtained under prescription 2I'e not Time bombs along the always risk-free. Medication containinq the fenphen Mekong call for a regional (fenflurarnine and phentermine) mix was pulled from the solution U.S, market in 1997 because of associated health problems. Besides damage to heart valves, the cocktail was linked to prirnary pulmonary tension (when tiny arteries inside the lung constrict, weakening the heart as it to keep blood flowing). While diet drLiQs taken with a doctor's advice may point out the keys to weight loss are simple: adequate exercise and a diet. Stomach-staplmq aside (a radical' measure for the seriously obese), there are no short cuts In Brief: Wronq-footed All the rage from-Taipei to The more prominent casualties include model Campbell and Spice Girl Emma Bunton. What are we talking about'? Platform shoes, Retro revivals from the 1970s, the footwear tends to inflict the same injuries it did then twisted ankles, broken bones and the like, But with the latest designs elevating wearers by as much as 25 centimeters, injuries have been more severe In Japan, two women died - one cracked her head after falling off her shoes; another was a passenger in a car that crashed because the woman driver could not brake properly in 15-cm boots .. Safety advocates are demanding health warrunqs. Perhaps anticipating law suits, shoe- http://www.asiaweek.com/asiaweek/magazine/99/1224/health.diet.html 8/20/01 Asiaweek.col11 I Health: Looking for Trouble I 12/24/99 Page 2 of2 nave to include caveats on labels (Jf fashion can kill. and Search: should acid" at the for the latest regional analysis Display Summaries (ID yes l no 8/20/01 • J}i\ngerous obsession with dieting prompts crackdown on slimming pills - smh.corn.au Home > World (\J~\i\'S Page 1 of2 > Article newS Ilational wodd opinion business ~. technology sport entertainment } multimedia classifieds jobs property cars place an ad extra personal finance travel education subscribe horne delivery eNewsletter archives Dangerous 0 with dieting crackdown on pills n August 3 2002 Israeli tro_oRs_anQJan~~-9uIlnto centre of N_<3blus . - -_ .... _. HeldjJibay Dirty N~\,\I_'y'()ckIT~_Cl[E:Ojustihe ticket for some Tokyo: Weighing in at less than 51 kilograms and standing 1.63 metres tall, the average 20-year-old Japanese woman possesses the sort of svelte figure that any weight-conscious Bridget Jones could The_Earthlsg(OttingJ§!ter only dream of. _ClJ:9.llrlQ.th_~ middle But that has not stopped increasing numbers of Japanese average or otherwise - turning to potentially deadly diet pil!s to get closer to the stick-like ideal represented by international fashion models and a growing number of their domestic idols. E UjJ~_CQ.~lrl1lrl9 w 0 C'ifLllia.i]J::JlI:Qrl.,_~.<l~ whis_tl_el:ilow"r Five people have died and almost 500 have fallen ill after taking the dangerous and poorly regulated herbal slimming aids from China, reports say. ~eywords-- The latest victim was a man who had been taking a brand of the pills not previously identified as potentially dangerous. today's edition: alll past 10 days This week China banned eight diet drugs containing fenfluramine, an appetite-suppressant which has been associated with heart valve problems and possibly liver failure, and which has been linked to a number of deaths in Asia. site guide In this section H idingir()l11hi~ The Japanese Health Ministry has issued warnings about 14 brands of imported diet aids, police have arrested one retailer and the Tokyo municipal government has ordered shops to withdraw two similar products. Stilt.e._n.otcompletely a romantic desert Fl.oLDania first to protect US from new co lift Ofic;l':-Ioyal w.orkers turn on departing whiteJarmer~ Famous for a low-fat diet of fish, seaweed, and green tea, Japan Anew start to the end of history has long been credited with a lifestyle that keeps tummies trim and cholesterol levels low. But such healthy habits have been changing in recent years, as the popularity of faity Western food sends waistlines outwards, even as the media and fashion industries apply psychological pressure in the opposite direction. This is partly because growing Asian affluence and Western influence have changed attitudes. In Maya government-funded study found that 5 per cent of girls in Tokyo junior schools had suffered from anorexia nervosa. Reports of eating disorders nationwide have risen tenfold since 1980. , . Psychologists say this is a global trend, but one that has been accelerated in Japan because women's value in society is determined more by appearance and age than in the West, where there are more opportunities to build careers based on ability. Nochiko Morikawa, a Tokyo psychotherapist, said: "In Japan the ideal woman is cute, like a child. If you put on weight, then you look older." Bookshops have whole sections devoted to slimming books and magazines of all kinds. One of them describes how to lose weight by wrapping oneself in Cellophane and singing karaoke; belting out one song is apparently the equivalent to jogging 1 00 http://www.smh.com.au/mticles/2002/08/02/1 028157845 881 .html 8/20/01 • DangerouS obsession with dieting prompts crackdown on slimming pills - smh.corn.au Page 2 of2 metres The Guardian Printer friendly version ~:~~~~ the Email toafriencl f8iter keywords archives for related stories (*Fee for full article) left I handheld (hovvto) tlletllbe~hifll cpnditi()D_S I J2Q,,-Cl.9' Copyright © 2002. The Sydney Morning Herald. http://www.smh.com.au/articles/2002/08/02/l028157845881.html advertise I c()ntact us 8/20/01 INfORMATION FOR PATIENTS ON THE WITHDRAWAL OF SUMMING PILLS CIVIA Y 2001) Page] 01'2 • This is the html version of the file bllQj/ww\f\l,-rr:LQ~Q\jJJkLouQIVorl</ITionitQ[~f~qlJ~ln~cJ/~'2i~t.YJ11essages/anomatsydf 'J automatically generates html versions of documents as we crawl the web. __________________________ To link to or bookmark this page, use the following uri: itt tp: / !'d\;". goog12. com! s e a r c h? c __ .C : >1(lH:-:8H 90tl14 c: 'rl W\V. Inca. gov. uk/ ou rwo r k z'mon i t o rs ; lJ1l>?d/ - sa fe t yme ss ac e s / anorpa ts . pdf+.slirmning+pill s+ &hl=e Google is no! cffiluned with the authors ofthis jJage nor rcsponsrblcfnr its content. I Page 1 INFORMATION FOR I) A TIENTS ON THE WITHDRAW OF SLIl\1lVHNG PILLS (MAY 20tH) This leaflet contains important information for people who are taking slimming pills ( anorectics appetite suppressants). You may have heard drugs are being withdrawn in Europe. slimming pills. Which slimming pills are being withdrawn? or read in the pre the following products: Duromine (phentcrmine) Ionamin (phentcrrnine) Dicthylpropion (amfepramone) Tcnuate Dospan (amfepramone) How can I tell if! am taking one of these drugs? Jfyou are taking slimming pills and you are not sure which ones they are, your pharmacist or doctor able to help. Why are these slimming pills being withdrawn again? This relates to a legal action; there are no new safety concerns with these pills. A European review of and benefits of these drugs was carried out. This led to a withdrawal of the products in April last year. companies which hold the licences for some of the products successfully appealed against the withdra leading to the licences being re-instated. This appeal has now been overturned in the European courts licences must be withdrawn again (in Europe). A final ruling with regard to the withdrawal ofthese p expected within a year. Why were these slimming pills withdrawn in the first place? The European review of the risks and benefits of these drugs concluded that trials do not show that th help people lose weight effectively. Also, although no new safety problems were identified with these some other anorectic products have been previously associated with heart and lung problems, in some A possible link with amfepramone and phenterrnine products cannot be totally excluded. When will the pills be withdrawn? The drugs will start to be withdrawn from 11 May. The withdrawal will be complete by 10 June, by time you should have stopped taking them. What should I do now? Should I stop taking my pills? If you are currently taking any of the above slimming pills, you should talk to your doctor as soon as http://216.239.35.] 00/search?q=cache:NQMx8H90H14C:w .. ./anorpats.pd1'+slimming+pills+&hl=en&ie=UTF- 8/20/01 INFORMATION FOR PATIENTS ON THE WITHDRAWAL OF SLIMMING PILLS (MAY 2001) Page2of2 about stopping your treatment. You may then need to be stop taking the pills gradually. Why do I need to stop taking the pills gradually? Some people may suffer from withdrawal symptoms when they stop taking this type of slimming pill particularly ifthey have taken them for more than 3 months. These symptoms can include low mood depression, anxiety, irritability, dizziness and disturbed sleep. Ifthese occur, they are usually worst b fourth day after stopping treatment. What do I need to do if I suffer these symptoms'? If you suffer these symptoms despite stopping the pills gradually and are worried about them. please s doctor who can advise on whether you need any treatment. How will I know if I've suffered harm as a result of taking slimming pills? If you are concerned about any worrying symptoms, such as breathlessness, palpitations (rapid or irre heart beat) or ankle swelling, which you have now or have had in the past while taking the pills, pleas doctor. I've been on slimming pills for years without ill effects what should I do now they've been with Weight loss should be managed long term and include modification of your diet, more exercise and at important lifestyle changes. See your doctor, who can advise you about other ways of losing weight. .IIZ/ ]-IP&paticnts anorectics 10050 I vFF.doc http://216.239.35.1 00/search?q=cache:NQMx8H90H14C:w .. ./anorpats.pdf+slimming+pills+&hl=en&ie=UTF- 8/20/0] ~~~~ "'- Slimm ing pi 11s at 13 put Debbie Oil the wa) to her heroin death Page 201'2 'Last Sunday, Debbie should have been starting a six-week detoxification session at Tolworth Hospital in South London,' Mrs Lnden revealed. 'But I can't understand it - it went wrong and they said she could only be treated as a day patient. ' In those last few days of her life, Debbie twicc slashed her wrists and her mother was fighting a desperate battle to try to get her booked into a hospital. 'I even begged one doctor to section her under the Mental Health Act just so I could get her round-the-clock attention,' said Mrs Linden. 'We'd been to our GP, we'd been together to Kingston Hospital, where she was eventually found dying in a corridor, and on that final Saturday 1 thought she was going to be adrn itted to Tolworth. 'She rang me on Saturday night from outside the hospital asking me to pick her up. But she went to some sort of drug place -Lord - I just clon't even know where it was.' Before she went out that night Debbie hugged her mother a said: 'I love you, Mummy. l ' always missed you, Mummy, and I want to thank you for everthing you've tried to do for me.' Mrs Linden said: 'It felt strange. I didn't know then, but perhaps she felt everything had gone. She had told me earlier in the day that although she was at ruck bottom-- she had no work and no money -- she wanted live. She was desperate to live.' Actress r'v101lie Sugden, who played Mrs Slocombe in Are You Being Served?, told last night how cast members realised something was wrong with Debbie when she appeared in the show. 'I remember going home one day and on drugs. Then I burst into tears. to my sons that I was so upset because I thought the pretty little girl was 'She used to have a faraway look on her face some of the time and we all suspected something. I'm so upset by news of her death ---it is such a shame for someone so young and pretty. I really feel for her mother.' John Inman, who played Mr Humphries, was in the United States last night promoting reruns of the cult programme when The Mail on Sunday told him of Debbie's death. 'What a terrible shame - I suspected that she was ill while she was in the show,' said 62-year-old Inman. 'She was often poorly and very peeky when we were filming. She was only in about six episodes but people remembered her as she was a n ice girl.' Debbie's death puts the spotlight on the debate over the decriminalisation of cannabis. Richard Branson, Sir Paul McCartney, Anita Roddick, Martin Amis and Harold Pinter are among those who favour such a move. Some, however, believe that experimentation with soft drugs such as cannabis can lead to the use of hard drugs like heroin. for Debbie, it was cocaine counteracted by alcohol and valium that would lead to her demise. In 1993, doctors told her she was' a month from death' if she didn't stop drinking and taking drugs. Her skin had gone grey and her liver had almost failed completely. Mrs Linden added: 'When you start off with babies, you never imagine that things could go so wrong. 'But I'll always remember her laughter. She used to say I was her best friend as well as her mother. I don't really blame the hospitals. After' all, everyone has tried to help her ever since this began.' ~.::JIWWW.Whalc.toldrugSISllmmlng.html 8/20/01 Page 2 of3 Agence France Presse June 9, 2002 SINGAPORE Related: S aciJal e 0 LcLea t h ,_sl1ff(; riIlglllld_etblc s HE Singapore girl made famous by the national airline is a slender and channing woman, but in reality she lives in a fatphobic society that has fuelled a multimillion-dollar diet-pill industry with tragic consequences. One woman is dead, another needed a liver transplant to save her life and several others are seriouslv ill after tak iuu a herbal slimming aid. 'c The women all took the Chinese-made "Slim 10" diet pill, which contained the banned substance Fcnfluraminc and has now been yanked from the market, but its highly publicised side-effects have had little impact on sales of other brands. In Singapore culture, "we don't accept people who arc , said Tcy Beng Hea, head of a weight-management progmmme at Singapore's Alexandra Hospital explaining the obsession with being thin. Most Singaporeans are petite and "the bigger ones tend to be the butt of jokes, adding to their insecurities" he said. A J 7year-old college student, at 1.6 metres (five three inches) tall and 60 kilograms (132 pounds), told AFP she had been taking diet pills on and off since she was 11. "I wanted to look better and I guess there's pressure lrom friends and magazines," she said. She quit the pills last year after a series of dizzy spells and headaches and said her weight reduction programme now was binge eating and: "I throw up after every meal." But slimming-pill retailers are laughing ali the way to the bank as they cash in on the lucrative business. One local chain, General Nutrition Centers, reaped between S$3 and S$4 million (US$1.7-2.2 million) in sales in 2001, according to chief executive Cynthia Poa. "Slim 10" is reported to have racked up S$3 million in sales in the five months it was on the market with 20,000 bottles sold at S$150 each. Tey cited a patient, a university graduate in her mid 20s, who was mildly overweight. He considered her "well proportioned" but she was not happy. When he asked her why, she looked him in the eye and said: "Do you think guys would look at girls like me who are fat?" At a recent forum on slimming which aimed to improve women's perspective on dieting and body image, Tay recalled that: "From my bird's-eye scan, most who attended were not seriously overweight." ; . The yearning to be thinner was compounded by advertisements, with media glorifying people who were underweight and medically unhealthy, Tey said. Normal-sized girls looked up to dangerously thin models as having the "todie-for" physique. The models were "so thin, they become exposed to certain health risks", he said. "Their immunity is compromised and their resistance to infection is very much reduced. http://www.singapore-window.org/sw02/020609af.htm 8/20/01 I Page 3 01'3 ~"'"':jngapore women dying to be thin c1 ~ I "We find that statistically they are more susceptible to tuberculosis, cancer, and their guts have problems absorbing nutrients.' "Women are their own worst enemy," said Singapore Women's \Veekly cditor-iu-chicfTara Barker. "Once, we did a story featuring normal-sized women in clothes. Almost immediately. we have women calling in, saying, 'why arc you showing big women?' "And when we interview men they say they prefer women with curves. But women .just don't believe them. "A magazine; is led by its readers. We can't force down their throats what they don't want to sec." Retailers say salcs of slimming pills slumped more than 30 percent because of the publicity surrounding "Slim 10" but it was not the end ofthe thin fad. Sales of meal replacement diet products rose; a simi lar amount. The medical watchdog Health Sciences Authority is now checking 45 Chinese-mack slimming products to see; if they have; been adultcratcd with svntuctic chemicals, and the importers of "Slim I (I" have 'heen charged with contravening the; poisons act. Police arc also investigating the "unnatural death" of 43-yearold Rani Raja who died early this month from liver failure after taking "Slim 10". But despite the cout-ovcrsy, pharmacist Chen Yee Ju backed diet pills if taken correctly and for a short term. "I've been in this industry for about five years and no one has come back reporting adverse side-effects. Slim I () is a freak case," he said. Home