Learn more about our services

QUALITY. DELIVERED.
When vision is at stake,
you want the very best for your patients.
At Eversight, we specialize in delivering the highest quality tissue and expert service
to make that possible.
Quality delivered
The Eversight network of community eye banks
provides a range of services to meet all your
needs, including:
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Specialized tissue preparation
Emergency tissue
Local customer support
Wet lab training for the latest
transplant procedures
• Tissue for charitable services and
medical missions
• Support for research and education
• Free resources for patients
Our team works closely with you to identify
your individual preferences, and each tissue is
carefully prepared to match the specifications
you choose. Using our online request system,
Midwire Match, you can easily schedule
surgeries and accept tissue offers at your
convenience.
Every tissue is recovered, evaluated and
prepared by experienced technicians under
the most rigorous standards in eye banking.
We provide comprehensive information,
including donor medical history, serologies, and
detailed imaging using the latest technology
in optical coherence tomography (OCT) and
specular microscopy.
Request tissue
Start your Eversight tissue request by calling
(866) 900-8119. Our normal business hours
are Monday through Friday, 7:30 a.m. to
6 p.m. An Eversight representative is always
available to accommodate emergency
tissue requests.
Tissue preparation services include:
• Penetrating Keratoplasty (PKP)
• Descemet Stripping Automated
Endothelial Keratoplasty (DSAEK),
Ultrathin and pre-loaded DSAEK.
• Descemet Membrane Endothelial
Keratoplasty (DMEK)
• Anterior Lamellar Keratoplasty (ALK)
• Kerato-limbal Allograft (KLA)
• Lamellar Keratoplasty (LKP)
• Intralase Enabled Keratoplasty (IEK)
• Scleral Tissue – whole globe, 1/2 sclera,
1/4 sclera, 1/8 sclera, or 6mm disc.
• Whole eyes, corneas, posterior poles, etc.,
for research and education
Eversight will notify you of tissue availability
at least 24 hours prior to the scheduled
surgery. Tissue will arrive the day of surgery,
unless otherwise indicated.
Eversight delivers, so your patients can see
life at its best. Working together, we can
restore sight and prevent blindness in our
communities, and give hope to people in
need through the healing power of donation,
transplantation and research.
Tissue Placement: (866) 900-8119 • Fax (734) 780-2730 • distribution@eversightvision.org
EVERSIGHT
SERVICES SERVICES
TISSUE STANDARDS
DMEK / EVERSIGHT
TISSUE STANDARDS
Surgeon: _________________________________ Office contact:___________________________________
Preferred contact: Email: ________________________ Fax: _______________ Phone: _______________
Tissue provided by Eversight is guaranteed to meet the tissue specification standards listed below,
established by Eversight’s Medical Advisory Committee, in accordance with EBAA Guidelines.
Elective PK/EK Standards
DSAEK Preparation Standards
Endothelial cell count: 2,000 or greater*
Post-cut thickness: 90-135µ Eversight standard
target (90-200µ policy range)
Death to procurement interval: Less than
24 hours (Eversight average: 13 hours)
Death to surgery interval: 14 days
(Eversight average: 6 days)
Tissue preferences:
❐❐ Endothelial cell count: _____________
❐❐ Death to procurement interval: _____
❐❐ Death to surgery interval: __________
Tissue specification options:
❐❐ Epithelium centration dot
❐❐ Trephine marking
DMEK Preparation Standards
Single partial trephination: ❐❐ 9.5mm Tissue specification options for
single partial trephination:
❐❐ 8.0mm
❐❐ 8.5mm
❐❐ 9.0mm
Tissue specification options for
double partial trephination:
❐❐ 7.25mm ❐❐ 7.5mm ❐❐ 7.75mm ❐❐ 8.0mm
Hinge location: ❐❐ Peripheral
Tissue specification options:
❐❐ Central
Orientation markings: ❐❐ No marking
Marking options:
❐❐ Micro stromal stamp/2mm punch combination
❐❐ Fold-over micro stromal stamp
❐❐ 1mm Trephination series
Markings: Peripheral alignment mark
Tissue specification options:
❐❐ “S” stromal stamp
❐❐ Micro stromal stamp
❐❐ 9mm Trephine marking
❐❐ Epithelium centration dot
Ultrathin DSAEK Preparation
Post-cut thickness: 40-90µ
Markings: Peripheral alignment mark
Tissue specification options:
❐❐ “S” Stromal stamp
❐❐ Micro stromal stamp
❐❐ 9mm Trephine marking
❐❐ Epithelium centration dot
Pre-loaded DSAEK Preparation
Post-cut thickness: 70-200μ
Markings: “S” Stromal stamp by request.
Upon receipt, the stromal stamp will appear
peripheral, unless a paracentral placement
is requested.
Graft size options:
❐❐ 8.5mm
❐❐ 8.0mm
*Endothelial cell count for emergency tissue requests may vary
based on tissue availability.
Tissue Placement: (866) 900-8119 • Fax (734) 780-2730 • distribution@eversightvision.org
EVERSIGHT SERVICES
DSAEK: Descemet Stripping Automated Endothelial Keratoplasty
DSAEK PREPARED TISSUE
Eversight preparation procedure
DSAEK prepared tissue
Eversight processing technicians use the Moria
Microkeratome System and a 300, 350, or
400µ microkeratome head to prepare corneal
grafts for surgeons performing Descemet
Stripping Automated Endothelial Keratoplasty
(DSAEK) procedures.
Eversight thickness policy range
90-200µ
Head size selection for each tissue is
determined by the processing technician
based on an algorithm that utilizes both the
pre-prepared tissue thickness, as well as
data specific to each technician and each
Moria system.
Pre- and post-prepared tissue thickness
measurements are obtained centrally from
optical coherence tomography (OCT) images.
Surgeons are provided with slit-lamp
biomicroscopy and specular microscopy
evaluations both pre- and post-preparation.
Eversight Support
Eversight is committed to ensuring that you are
both comfortable and confident as you begin
to offer DSAEK to your patients. We provide a
number of practice opportunities, including
wet lab courses, training tissue, supply kits,
and use of our facility with the assistance of an
Eversight processing technician.
Epithelium side
Eversight standard target thickness
90-135µ
Ultrathin thickness policy range
40-90µ
Markings
Peripheral alignment mark
Options
"S" Stromal stamp with equidistant placement
(paracentral or peripheral placement available
by request).
Micro stromal stamp
9mm Trephine marking
Epithelium centration dot
Additional arrangements of stromal bed
dots or streaks by request (for example,
peripheral stromal hash marks at the four
cardinal directions).
Stromal Stamping
The following examples show different
placements of the S stamp. Proportions are
to scale with a typical 11-12mm cornea (dark
blue), typical 10mm cut bed (light blue),
surgeon punch button size (varies, but the
examples use an 8.0mm) and Eversight
DSAEK "S" stromal stamp.
Alignment Mark
Equidistant DSAEK
Stromal Stamp
Paracentral DSAEK
Stromal Stamp
Peripheral DSAEK
Stromal Stamp
Questions? Contact: Lauren Johnson • ljohnson@eversightvision.org • (800) 247-7250 ext. 2597
EVERSIGHT SERVICES
PRE-LOADED DSAEK TISSUE
PRE-LOADED DSAEK TISSUE
Eversight offers pre-loaded tissue for your DSAEK surgeries so you can spend less time in the
OR and more time focusing on your patients.
Pre-loaded Tissue Services
Getting Started
Tissue for DSAEK is prepared according to
your specifications.
When you are ready to begin using pre-loaded
tissue, Eversight will assist in scheduling an
EndoGlide representative to provide training
prior to or during your first surgery, at no cost.
Slit-lamp biomicroscopy, specular microscopy
and OCT evaluations are performed pre- and
post-preparation. The graft is then punched to
the desired size prior to being loaded into the
Coronet EndoGlide Ultrathin Tissue Delivery
System™.
The graft is shipped inside the Glide cartridge,
and contained within a vial of Optisol GS.
When Eversight pre-loaded tissue arrives,
no additional preparation is needed. Simply
remove the EndoGlide from the storage
media and begin the insertion process.
EndoGlide Ultrathin Tissue
Delivery System*
Pre-loaded DSAEK prepared tissue
Eversight thickness policy range
70-200µ
Markings
“S” Stromal stamp or micro stromal stamp
by request. Upon receipt, the stamp will
appear peripheral, unless a paracentral
placement is requested.
Graft trephination size options
8.0mm or 8.5mm
Proven to streamline DSAEK surgery and deliver
optimal patient outcomes, the EndoGlide is
consistent, easy to use, and offers maximum
surgeon control.
Once inserted, EndoGlide creates a “closed
system” that maintains anterior chamber
stability and inhibits tissue inversion.
Published clinical studies – available online at
eversightvision.org – support positive patient
outcomes with less endothelial cell loss
compared to other devices.
*A one-time purchase of EndoGlide Forceps™
from Coronet is required. Learn more at
www.coronetmedical.com.
Questions? Contact: Lauren Johnson • ljohnson@eversightvision.org • (800) 247-7250 ext. 2597
DMEK: Descemet Membrane Endothelial Keratoplasty
EVERSIGHT
SERVICES SERVICES
DMEK / EVERSIGHT
DMEK PREPARED TISSUE
Eversight Preparation Procedure
Tissue is mounted on a vacuum block to
perform a 360o partial trephination through
the Descemet membrane. Surgical grade
trypan blue is then used to stain the tissue for
increased visualization.
A 360o partial dissection is then performed
1-2mm interior to the trephination score.
Next, the Descemet membrane is manually
peeled from the stromal bed, leaving a small
hinge attached within the trephinated button.
After that, the Descemet membrane is gently
adhered onto the stromal bed, and the tissue is
placed in a corneal viewing chamber containing
Optisol GS.
Before transport to the surgery location,
the tissue undergoes additional specular
and slit lamp evaluations.
As with any new surgical procedure, Eversight
understands the importance of providing
flexible options to surgeons as techniques are
refined. If you have questions or need alternate
preparation options, please contact Eversight.
DMEK tissue specification options
Button Trephination
Single partial trephination: 9.5mm is the
standard and largest size offered.
Other options: 8.0mm, 8.5mm
and 9.0mm.
Double partial trephination: 7.25mm, 7.5mm,
7.75mm, and 8.0mm.
Hinge Location
Our standard DMEK tissue has a peripheral
hinge located 1-2mm interior to the trephination
line, identified by a scleral marking.
Orientation Markings
(Available by surgeon request)
Micro Stromal Stamp/
2mm Punch Combination
Before the Descemet membrane is returned
to the stromal bed, a 2mm hole is punched
through the stroma near the periphery of
the trephinated button. After the Descemet
membrane is returned to the stroma, the
tissue is placed epithelial side up and the
micro “S” is stamped onto the stroma through
the trephinated hole. The 2mm punch is
then replaced into the stromal bed.
Fold-Over Micro Stromal Stamp
Before the Descemet membrane is returned
to the stromal bed, the peripheral edge is
folded over onto the rim and the micro “S”
stamp is applied to the stromal side of the
Descemet membrane.
1mm Trephination Series
After the Descemet membrane has been gently
adhered back onto the stromal bed, three 1mm
circles are punched through it so that the circles
are dissected by the trephination line.
Circles are situated at the 12, 1, and 4 o’clock
positions when viewed from the cornea’s
endothelial side.
Eversight Support
Eversight is committed to ensuring that you are
both comfortable and confident as you begin
to offer DMEK to your patients. We provide a
number of practice opportunities, including wet
lab courses, training tissue, supply kits and use
of our facility with the assistance of an Eversight
processing technician.
See opposite side for diagrams.
Alternatively, a centrally placed 2x2mm
hinge is also available by request.
Questions? Contact: Lauren Johnson • ljohnson@eversightvision.org • (800) 247-7250 ext. 2597
DMEK: Descemet Membrane Endothelial Keratoplasty
EVERSIGHT
SERVICES SERVICES
DMEK / EVERSIGHT
DMEK PREPARED TISSUE
Epithelium
Endothelium
Stromal bed
Epithelium
2mm Punch/Micro Stromal
Stamp Combination
After creation of either the peripheral or
central hinge, a 2mm trephine is used to
punch through the remainder of the
stromal bed. The 2mm punch plug is
removed and the Descemet is returned to
the stromal bed. The stamp is then applied
to the stromal side of Descemet through
the 2mm hole from the epithelium side of
the tissue. The 2mm punch plug is
replaced during transport.
Endothelium
Fold-Over Micro Stromal Stamp
After creation of the peripheral hinge,
the edge of the Descemet is left on a
dry area of the scleral rim, and the
stamp is applied directly to the stromal
side of Descemet. The Descemet is then
returned to the stromal bed.
Single Partial
Trephination Options
Standard: 9.5mm
Other options: 8.0, 8.5,
and 9.0mm
Double Partial Trephination Options
Standard 9.5mm single partial trephination
7.25, 7.5, 7.75, or 8mm double partial trephination
1mm Trephination Series
(View from endothelium)
After creation of either the peripheral or
central hinge, the Descemet is returned to
the stromal bed. A 1mm trephine is then
used to punch through the Descemet at
the periphery of the partially trephinated
button. When viewed from the endothelium
side, the 1mm trephine series will be seen
as half-circles at 12, 1, and 4 o'clock.
Corneas and markings are to scale and shown at approximately 300%.
Questions? Contact: Lauren Johnson • ljohnson@eversightvision.org • (800) 247-7250 ext. 2597
EVERSIGHT
SERVICESSERVICES
CHARITABLE SERVICES
DMEK / EVERSIGHT
GIFT OF SIGHT PROGRAM
No one should be denied the
gift of sight.
Eversight offers hope for your patients
with limited income or inadequate
insurance by accepting reduced-fee
requests for corneal tissue.
Our Gift of Sight program, funded solely
through charitable contributions, waives
or reduces the fees associated with
transplantation.
Over the years, our program has helped
hundreds of grateful recipients. Now, these
people can work, care for their family and
live an independent life.
Making your request
Requests can be made by completing the
Gift of Sight Charitable Services Request
Form (available at eversightvision.org)
and returning it to the Eversight Tissue
Placement Department.
All requests will be reviewed within three
business days, and you will be notified of
approval.
When approved, Eversight will waive or reduce
our tissue processing fee, plus any shipping
charges that may be incurred, and bill the
hospital/surgery center for the negotiated fee.
Please provide one week's notice for your
charitable services request to allow ample time
for processing and approval. In the case of
an emergency, your request will be reviewed
immediately.
As part of our Gift of Sight program, we ask
that you join us in providing financial relief
to patients in need by reducing your surgery
fees, whenever possible.
See the impact
Dan Burton began having
problems with his left eye when
he was two years old. As a teenager,
he underwent a cornea transplant
that saved his eye, but did little to
improve his vision.
Nearly 60 years later, an infection robbed
Burton of his remaining vision, and he was
told that another cornea transplant was
the only treatment.
For him, the news could not have come at a
worse time. Burton was always a hard worker,
and owned and operated his own business,
building houses and installing flooring.
But the years of hard work eventually took
their toll on Burton’s body, and he suffered
a heart attack.
“Everything went down the drain for me,”
he recalls. “When it started, it was like a
big ball rolling down a hill.”
When he found out he was going to
need another cornea transplant, he was
unemployed and had no insurance.
He didn't know where to turn.
Much to his surprise, help was on the way.
His eye doctor, Dr. Miriam Schteingart, alerted
Eversight that she had a patient who urgently
needed a cornea transplant, but was unable
to afford the costs associated with the surgery.
Eversight quickly made the arrangements to
provide the necessary corneal tissue, waiving
our usual fees, and Burton underwent a
successful cornea transplant.
Today, he is able to live a productive,
independent life thanks to his renewed sight.
*Revised January 26, 2016 3:16 PM
Tissue Placement: (866) 900-8119 • Fax (734) 780-2730 • distribution@eversightvision.org
EVERSIGHT
SERVICES SERVICES
RESEARCH
DMEK / EVERSIGHT
RESEARCH PROGRAM
Eversight provides resources that help researchers advance cures and treatments
for eye diseases. Components of our program include:
TISSUE
Eversight provides more than 3,000 tissues for research
and education annually. We work to understand your
specific research objectives to ensure you receive
the tissue you need. Our dedicated research team
is trained to recover tissue under strict time and
environmental conditions to preserve the integrity of
precious biological specimens. In addition, Eversight
offers comprehensive donor medical, ocular and social
history information with serology results upon request.
Tissues available for research include:
❐❐ Whole eye
❐❐ Posterior pole
❐❐ Cornea
❐❐ Conjunctiva
❐❐ Lens
❐❐ Retina
Additional tissue types and preservation techniques available upon request.
FUNDING
Eversight provides seed grant funding to help develop
and conduct preliminary research projects. Several of
these grants have led to larger studies and significant
financial support from the National Institutes of Health.
Since 1980, we have awarded more than $3 million
to support research investigating critical diseases
like glaucoma, diabetic retinopathy and macular
degeneration, as well as furthering advances in
corneal surgery and eye banking practices.
PARTNERSHIPS
Eversight collaborates with researchers and surgeons
to improve eye banking practices. By sharing ideas,
we are able to identify key improvement opportunities
that benefit the greater donation, transplantation and
research communities. We share these best practices
through presentations at conferences, scientific journal
publications and educational forums.
Creating an Innovative
Research Program
Eversight is building an
innovative research program centered
on a diseased eye donor registry, data
repository and biorepository to provide
scientists with well-characterized,
human ocular tissue.
In collaboration with some of the
world’s leading academic institutions,
the program will deliver a system for
collecting, processing, storing and
distributing diseased and healthy
ocular tissue, supplemented by
detailed donor information (i.e.
medical, social and ocular data).
The program is projected to launch
in late 2016.
For questions regarding the donor
registry/biorepository or research
grant funding, please contact:
Gregory H. Grossman, Ph.D., CEBT
Director of Research Programs
(216) 706-4233
ggrossman@eversightvision.org
For ocular research tissue inquiries,
please contact:
Colleen Vrba, CEBT
Corporate Research Coordinator
(312) 469-5552
colleen@eversightvision.org
For more information about our program, grant application forms, and examples of
Questions? Contact:
Lauren
Johnson
• ljohnson@eversightvision.org
• (800) 247-7250 ext. 2597
previously
funded
research
projects, visit eversightvision.org/research
EVERSIGHT
SERVICES SERVICES
RESEARCH
DMEK / EVERSIGHT
KEY PARTNERSHIPS
Eversight partners with researchers and academic institutions to make vision a reality
for all people in need.
Our growing list of academic partners
includes:
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Case Western Reserve University
Catholic University of Korea
Cleveland Clinic Foundation
Loyola University Chicago
Michigan State University
Northern Illinois University
Northwestern University
University of Chicago
University of Illinois at Chicago
University of Michigan
Wayne State University
Eversight also supports research efforts at:
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Duke University
Harvard University
Indiana University School of Medicine
Johns Hopkins University
Stanford University
University of Arizona
University of California Los Angeles
University of California San Diego
University of Colorado Denver
University of Miami
University of Southern California
Eversight’s national research partners include:
• Vision Share
• The National Disease Research Interchange
• Foundation for Fighting Blindness
Research Committee of the
Eversight Board of Directors
Jonathan Lass, M.D., Chair
Professor, Department of Ophthalmology and
Visual Sciences, Case Western Reserve University
Rashid L. Bashshur, Ph.D.
Senior Advisor for e-Health, University of Michigan
Health System; Professor Emeritus at the University
of Michigan School of Public Health, Department
of Health Management and Policy
Marilyn R. Lindenauer, M.P.H.
President Emerita, Eversight
Julie Lowery, Ph.D.
Associate Director, VA Center for Clinical
Management Research,VA Ann Arbor
Healthcare System
Elspeth Moore, M.L.S.
Kevin Ross, M.P.H.
President and CEO of Eversight
Maria A. Woodward, M.D.
Assistant Professor of Ophthalmology and
Visual Sciences, University of Michigan
Kellogg Eye Center
For more information about our program, grant application forms, and examples of
Questions? Contact:
Lauren
Johnson
• ljohnson@eversightvision.org
• (800) 247-7250 ext. 2597
previously
funded
research
projects, visit eversightvision.org/research
EVERSIGHT
SERVICES SERVICES
MEDICAL ADVISORY COMMITTEE
DMEK / EVERSIGHT
MEDICAL ADVISORY COMMITTEE
Medical Advisory Committee members combine proven leadership and years of experience to
provide clinical guidance to Eversight and its affiliates. All committee members are practicing
ophthalmologists and Fellows of the American Academy of Ophthalmology (FAAO).
Shahzad I. Mian, M.D. (Committee Chair)
Associate Professor of Ophthalmology and Visual
Sciences at the University of Michigan (U-M) Kellogg
Eye Center; Terry J. Bergstrom Collegiate Professor
for Resident Education in Ophthalmology and Visual
Sciences at the U-M; Associate Chair for the U-M
Education Department
William H. Constad, M.D.
Clinical Professor at Rutgers Medical School and
affiliated with Jersey City Medical Center and St.
Barnabas Medical Center; Hudson Eye Physicians
and Surgeons David Chu, M.D.
Associate Professor of Clinical Ophthalmology at the
Institute of Ophthalmology and Visual Science, New
Jersey Medical School of Rutgers University; Cornea and
Laser Eye Institute; Director of Metropolitan Eye Research
and Surgery Institute of New York and New Jersey
Catharine J. Crockett, M.D.
Eye Surgical Associates, Bloomington, Ill
Jeffrey Goshe, M.D.
Cleveland Clinic Cole Eye Institute
Pankaj C. Gupta, M.D. Director of Cornea and Refractive Surgery,
Department of Ophthalmology and Visual Sciences
and Residency Program Director at University
Hospitals in Cleveland
Gregory I. Halperin, M.D. Gailey Eye Clinic, Bloomington, Ill
Jonathan H. Lass, M.D.
Charles I. Thomas Professor in the Department of
Ophthalmology and Visual Sciences at Case Western
Reserve University in Cleveland; University Hospitals
Eye Institute
Mark A. Lister, M.D. Director of Cornea, External Disease and Ophthalmic
Surgery at Metropolitan Hospital; Ocean County
Medical Center; Hoboken University Medical Center
in Jersey City; Co-director of corneal services at
St. George’s University Medical School; Director of
Cornea Services at Children’s Eye Care Center of New
Jersey, at Clara Maass; Clinical Associate Professor
at New York Medical College and Rutgers University
Medical School
Mark McDermott, M.D., M.B.A., CPE, FARVO Professor, Department of Ophthalmology, Wayne
State University School of Medicine Kresge Eye
Institute
Allen S. Roth, M.D., F.A.C.S. Assistant Clinical Professor of Ophthalmology,
Department of Surgery at the Cleveland Clinic
Lerner College of Medicine of Case Western
Reserve University
Roni Shtein, M.D., M.S. Associate Professor of Ophthalmology and
Visual Sciences at the University of Michigan
Kellogg Eye Center
H. Kaz Soong, M.D.
Professor of Ophthalmology and Visual Sciences at
the University of Michigan Kellogg Eye Center and
Chief of the Cornea Service
Alan Sugar, M.D., F.A.C.S.
Professor of Ophthalmology and Visual Sciences at
the University of Michigan Kellogg Eye Center and
Department Vice Chair
Joel Sugar, M.D., F.A.C.S. Professor in Ophthalmology, Cornea Service and
Vice Chair of Clinical Operations at the University
of Illinois School of Medicine Department of
Ophthalmology
Elmer Y. Tu, M.D.
Professor of Clinical Ophthalmology and Visual
Sciences and Director of the Cornea Service at the
Illinois Eye and Ear Infirmary at the University of
Illinois College of Medicine
Maria A. Woodward, M.D.
Assistant Professor of Ophthalmology and Visual
Sciences at the University of Michigan Kellogg
Eye Center