E - Newsletter CRC HKL - Clinical Research Centre

Issue 1, Volume 1
JUNE 2016
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Ijazah Sarjana Perubatan
E - Newsletter CRC HKL
HOW
TO
D O RES EA RCH IN HO SP ITA L
KUA L A LUM P UR
C L I N I C A L
R E S E A R C H
C E N T R E
H O S P I T A L
K U A L A
L U M P U R
MULA
M e s s a g e
D R .
H J H
f r o m
S A L I N A
A DV I S O R
A B D U L
A Z I Z
Assalamualaikum And Warm Welcome To Our Readers,
On behalf of the team, I am proud to present the first Clinical Research Centre Hospital Kuala Lumpur
(CRC HKL) Newsletter for 2016. My heartiest appreciation to those of you who have contributed, without which this would not have been possible. Through the creation of our first newsletter, we hope to
promote research culture; make it interesting and informative to seasoned as well as new researchers.
It has always been our mission to improve the quality of health and healthcare through the application
of a high-quality and credible clinical research. This newsletter will be a collegial platform to share
knowledge, experience and success in various aspect of clinical research from recognition to awards to
publication.
In this edition, we have included a list of publications by our distinguished colleagues in Hospital Kuala
Lumpur. We would like to encourage you to notify us your publications or achievements so that we
may build this section in the following editions. We also highlight the latest research workshops/
trainings organized with great participation and support from various healthcare personnel. I sincerely hope that these efforts would
assist in making us more receptive as well as help to foster and motivate an interest to embark in clinical research.
Staf HKL
Bukan Staf HKL
*termasuk Pegawai Perubatan di bawah program
Membawa salinan borang
IA-HOD-IA dan borang
kelulusan JEPP (jika ada)
ke CRC HKL
Mendaftar penyelidikan di NMRR
Mendapatkan kelulusan JEPP dan
membawa salinan surat kelulusan
etika JEPP ke CRC HKL
Mendaftar penyelidikan di
CRC HKL (borang HKL/
HCRC/AK-02-01, HKL/
HCRC/AK-02-02)
Mendaftar penyelidikan & menandatangani persetujuan penyelidik
di CRC HKL (boring HKL/HCRC/AK02-01, HKL/HCRC/AK-02-02)
CRC HKL Newsletter aims to deliver to you topics or issues of interest for all our readers. We will release our newsletter biannually.
Readers can get the electronic version of our e-newsletter in the CRC website at www.crc.gov.my. Let us know your feedback and
ideas on how we can collaborate to make HKL our nation’s main clinical hub.
And lastly, congratulations to the editorial team for this wonderful beginning. “May today’s success be the beginning of tomorrow’s
achievements”. I look forward to an enjoyable and enlightening read in the many newsletters to follow. I hope the readers will enjoy
the newsletter as much as I do.
Thank you.
O R G A N I Z A T I O N C H A R T
C R C H K L
I N S I D E
T H I S
I S S U E :
Organization
Chart CRC HKL
1
Research Flow in
HKL
2
Trainings and
Workshops
34
List of Publications 2014
5
List of Publications 2015
Mendapatkan
kelulusan JEPP (jika
belum ada)
Membawa salinan
surat kelulusan etika
JEPP
Kakitangan CRC HKL
melengkapkan
borang HKL/HCRC/AK
-02-01
Mulakan peyelidikan
Rujukan:
IIR – Investigator Initiated Research
JEPP – Jawatankuasa Etika Penyelidikan Perubatan
(MREC)
HKL/HCRC/AK-02-01: Agreement for Undertaking
Research at Hospital Kuala Lumpur
HKL/HCRC/AK-02-02: Hospital Kuala Lumpur
SERVICES REQUIRED FOR THIS RESEARCH
PROJECT
HKL/HCRC/AK-02-03: Head of Department
Agreement/Director of Hospital Kuala Lumpur
Agreement
Mengusulkan borang HKL/HCRC/AK
-02-03 yang telah dilengkapkan
Ketua-Ketua Jabatan kepada
Pejabat Pengarah
Mendapatkan persetujuan
Pengarah, Hospital Kuala Lumpur
untuk menjalankan penyelidikan di
Hospital Kuala Lumpur
Kembali ke CRC HKL dengan borang
HKL/HCRC/AK-02-03 yang telah
ditandatangani ketua jabatan dan
Pengarah HKL
6
HKL Research Day
7
Announcement
Announcements
Mendapatkan persetujuan Ketua
Jabatan bagi jabatan-jabatan HKL
yang tertera di borang HKL/HCRC/
AK-02-02, menggunakan borang
HKL/HCRC/AK-02-03
8
Kakitangan CRC HKL melengkapkan
borang HKL/HCRC/AK-02-01
Mulakan peyelidikan
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January 2016 - First CME collaborative workshop 
with Pediatric Department, HKL entitled
“Introduction to Research”.
January 2016 - NMRR User & Research (IIR)
Registration Training.


February 2016 - Interdepartmental workshop with
Nursing Department, HKL.
February 2016 - CRC HKL & CRM Family Day with
Bowling Tournament which was held at Wangsa
Walk Bowl, One Utama.
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March 2016 - CRC HKL has organized Good Clinical 
Practice Workshop which was held at Seminar
Room Level 5, SCACC specially to HKL staffs.
May 2016 - Introduction to Statistic Course which
was held at Institut Kesihatan Umum, Bangsar.

April 2016 - CRC HKL has organized Research 
Methodology Workshop which was held at Seminar Room CRC HKL, delivered by Prof. Dr. Syed
Zulkifli Dr. Zuraidah & Dr. Husyairi from (UKMC)
and Prof. Dr. Sharmini Selvarajah.
May 2016 - CME session of Interdepartmental
training with Pediatric Department, HKL, entitled
“Writing Research Proposal”.

April 2016 - Interdepartmental Workshop with
Radiology Department, HKL entitled “Critical
Appraisal” which was held at Seminar Room CRC
HKL.


-

February 2016 - Interdepartmental workshop with
Orthopedic Department, HKL entitled “How to
Present a Research Proposal & Its Protocol: A
Guide for the Beginner”.
February 2016 - Interdepartmental workshop with
Pharmacy Department HKL entitled “Developing
Your Research: Brainstorming, Formulating
Research Question Plan”.
E
Trainings & Workshops
Trainings & workshops

4
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May 2016 - CRC HKL & CRM was collaborated in
organizing “Becoming a Clinical Trial Investigator”
workshop which was given by Dr. Mahadevan,
Head of CRC Seremban and Ms. Carrie Koh from
Paraxel.

May 2016 - Good Clinical Practice Refresher has
been organized with the collaboration between
CRC HKL & CRM with the speaker Ms. Eelaine Tan
from Quintiles.
May 2016 - Interdepartmental training with Nursing Department, HKL, entitled “Data Management”
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PUB LICAT IONS & ACHIEVEMENT S
No. Year Name of Researcher
Department
Title of Research
Journal
1.
2014 Dato’ Dr. Hussain
Imam B. Hj Muhammad Ismail
Pediatric
Neurologic manifestations and complications of
pandemic influenza A H1N1 in Malaysian children: What have we learnt from the ordeal?
2.
2014 Dr. Chee Kok Yoon
Psychiatry
A Review Of Schizophrenia Research In Malaysia MJM Supplement
from 2000-2013
3.
4.
5.
6.
7.
8.
9.
2014 Dr. Chee Kok Yoon
2014 Dr. Hiew Fu Liong
2014 Dr. Hiew Fu Liong
2014 Dr. Noorliza Chemi
2014 Dr. Shanti
Viswanathan
Psychiatry
Neurology
Neurology
Psychiatry
Neurology
2014 Dr. Shanti
Viswanathan
Neurology
2014 Dr. Shanti
Viswanathan
Neurology
Outcomes of Patients With First-Episode Schizophrenia At One-Year Follow-up: Findings From
National Mental Health Registry In Malaysia
Brain &
Development
Journal
Schizophrenia
Research
Novel Mutation in the Gene Encoding Acid a-1,4- Case Reports in
Glucosidase in a Patient with severe Late-Onset Neurological
Glycogen Storage Disease Type ii (Pompe's
Medicine
Disease)
Arakan Neuropathy: Axonal Motor Sensory
Polyneuropathy Among Myanmarese Refugees
A Review Of Substance Abuse Research In
Malaysia from 2000-2013
International
Scholarly Research
Notices
The frequency of anti-aquaporin-4 IgG antibody, Multiple Sclerosis
in Neuromyelitis Optica and its spectrum
International
disorders at a single tertiary referral center In
Malaysia
Central nervous system Erdheim Chester disease Neurology India
presenting with raised Intracranial pressure and
cerebellar signs mimicking neurosarcoidosis with
secondary cerebral venous thrombosis
Waste Tongue In Neuromyelitis Optica Spectrum Neurology India
Disorders due to Hypoglossal nerve involvement
Pediatric
Dental
Aneurysmal Bone Cyst Of The Mandible: A Care
Report
Pediatric Dental
Journal
11. 2014 Dr. Tan Teik Hin
Nuclear
Medicine
False negative 99mTc-HDP three-phase bone
scintigraphy and 99m-Tc besilesomab scan in
detecting tibia osteomyelitis concomitant with
necrotizing fasciitis: A Case Report
World Journal of
Nuclear Medicine
13. 2014 Pn. Lai Jun Yi
Langerhans cell histiocytosis in an adult - a rare,
life-threatening and not to be missed
The Medical
Journal of Malaysia
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PUB LICAT IONS & ACHIEVEMENT S
No. Year Name of Researcher
Department
Title of Research
Journal
1.
2015 Dr. Chee Kok Yoon
Psychiatry
Utility of AD8 Screening Tool (AD8) as a self- or
informant-rating tool for Cognitive Impairment
in Parkinson's disease: Comparison between
AD8 and Montreal Cognitive Assessment
Instrument (MoCA)
Journal of
Neuropsychiatry &
Clinical
Neurosciences
2.
2015 Dr. Hiew Fu Liong
Neurology
Subacute neuropathy among the Rohingya in
Malaysia
Neurology Journal
3.
2015 Dr. Izzaty Dalawi
CRC HKL
Gorlin Syndrome Case Report: Clinical and
Radiological Correlation
Malaysian Journal
of Dermatology
4.
2015 Dr. Jama'iah Mohd
Sharif
Pediatric
Dental
Multidisciplinary Approach of Managing Patient
with Obstructive Sleep Apnea
Pediatric Dental
Journal
5.
2015 Dr. Kunasilan A/L
Subramaniam
Forensic
Ruptured Saccular Intracranial Aneurysm
associated with Arteriovenous Malformation:
A Fatal Diagnosis
Malaysian Journal
of Pathology
6.
2015 Dr. Ngu Lock Hock
Genetic
Eyes on MEGDEL: Distinctive Basal Ganglia
Involvement in Dystonia Deafness Syndrome.
Neuropediatrics
Journal
7.
2015 Dr. Ngu Lock Hock
Genetic
Carbamoylphosphate synthetase 1 (CPS1)
deficiency: clinical, biochemical, and molecular
characterization in Malaysian patients
European Journal
of Pediatrics
8.
2015 Dr. Ngu Lock Hock
Genetic
N-carbamylglutamate is an effective sole
Neonatology
treatment of acute neonatal hyperammonaemia Journal
in a patient with Methylmalonic Aciduria.
9.
2015 Dr. Paul Vijayandran
Neurosurgery
Outcome of patient diagnosed with gliomas at
Hospital Kuala Lumpur (HKL) from January 1,
2011 - December 31 2013
Medical Journal of
Malaysia
10. 2015 Dr. Sumithra Devi A/
P Valiapan
Obstetric &
Gynecology
Elevated serum progesterone levels on the day
of human chorionic gonadotrophin
administration and the impact on pregnancy
rates in gonadotrophin releasing hormone
analogue in-vitro fertilization cycles
Journal of Fertility
and Sterility
11. 2015 Dr. Sunita a/p
Bavanandan
Nephrology
Budget Impact Analysis of Peritoneal Dialysis vs Value in Health
Conventional In-Centre Hemodialysis in Malaysia Regional Issues
12. 2015 Dr. Wong Teck Huat
Ophthalmology Clinical Outcome of autologous cultivated limbal Journal of Stem Cell
transplantation therapy for patients with ocular Research &
surface disease
Therapy
Dermatology
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MJM Supplement
10. 2014 Dr. Shina Mohd
Ariffin
12. 2014 Dr. Thiageswary
Umapathy
P a g e
Nuclear
Medicine
Influence of CEA on Diagnostic Performance of
FDG PET-CT in Detecting Recurrent Colorectal
Cancer
Medical Journal of
Malaysia
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ANNOUNCEMENT
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N e w s l e tt e r
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H K L
ANNOUNCEMENT
UPCOMING EVENTS
1) Hospital Kuala Lumpur Research Day 2016
3) Good Clinical Practice Workshop
Venue: Main Auditorium, HKL
Venue : Seminar Room, Level 5, SCACC
Date/Time: 22nd September 2016 / 8.30am—5 pm
Date : 25 - 27 October 2016
*It will be officiated by Datuk Dr. Shahnaz Binti Murad,
Deputy DG, Ministry of Health, Malaysia
*Open to all HKL staffs to participate in Poster/
Oral Presentation Competition.
4) NIH Research Week 2016 Incorporating the 19th NIH
Scientific Seminar
Venue: Institute for Health Management, Kuala Lumpur
Date : 19 –23 November 2016
2) National Medical Research Registry (NMRR) User and
Theme: Transforming Health System Through Research:
Research Registration Training.
Towards Sustainability
Venue : Caw. Teknologi Maklumat (CTM), Level 7, SCACC.
Date : 11 October 2016
GREETINGS FROM US

Salam Ramadhan (6 june—5 july 2016)
E D I T O R I A L
T E A M
ELIGIBILITY CRITERIA

Abstract should be based on original research and should NOT have been presented at any international scientific
conferences.

Participants may submit more than ONE abstract.

Abstracts must be submitted in ENGLISH.

Studies conducted in Ministry of Health facilities must submit NMRR ID with their abstract.

Only studies involving human subjects will be considered. This includes clinical studies (observational and interventional) and cross sectional surveys, case reports & case series.

The Scientific Committee will review and reserve the right to decide on the acceptance of abstracts for poster and
oral presentation.
ADVISOR
DR. HJH SALINA ABDUL AZIZ
EDITOR-IN-CHIEF
DR. IZZATY DALAWI
SPECIAL THANKS TO
DR. MURNILINA ABDUL MALEK
DR. LEE JEN VEN
& ALL CRC HKL TEAM
C O N T A C T
U S
CLINICAL RESEARCH CENTRE, HSOPITAL KUALA LUMPUR,
LEVEL 7, SPECIALIST COMPLEX & AMBULATORY CARE CENTRE
(SCACC), JALAN PAHANG, 50586 KUALA LUMPUR.
PHONE NO. : 03-26155555 EXT 1144/1622
YOU’RE WELCOME TO CONTRIBUTE (NEWS, EVENTS,
PUBLICATIONS, ARTICLE OF INTEREST, ETC) TO US BY
EMAIL:hosp.crchkl@gmail.com or izzatydalawi@crc.moh.gov.my