Cellicon Lab Inc. Brochure - in

The logotype of Cellicon Lab symbolizes the human shape.
www.celliconlab.com
Head Office
Daejeon Bio-venture town #304, 1662, Yuseong-daero, Yuseong-gu, Daejeon, South Korea
Factory
58, Baekseokgongdan 1-ro, Seobuk-gu, Cheonan-si, Chungcheongnam-do, South Korea
watch arrow, that can turn time back and make
human face healthy and beautiful.
www.celliconlab.com
www.celliconlab.com
R&D
R&D
Business Area
Molecular Design Method
Cellicon Lab specializes in high-functional and skin-friendly cosmeceutical peptides. Molecular design
technology is a method generally used in developing new materials in drugs. Cellicon Lab is capable
to develop a new peptide with more effective at proper cost.
Raw Materials
Development of new peptide which improves various skin concerns
Synthesize of combinated fusion peptide with a high active molecule and peptide
Synthesize of new peptide and natural ingredient complexed composition
Optimized Manufacturing System for Peptide
At the market, peptide cosmetics usually contain low content of peptide due to the extremely high cost
of peptide. By decreasing the manufacturing cost with innovative system of Cellicon Lab, every product
keeps the effective content dosage of peptide rigorously.
ODM / OEM
Produce ODM products with high active peptide
Development of various formulation based on consumers’ various needs
Small quantity batch production
Brand
Cosmeceuticals
Jeu’Demeure
Anti-aging
Anti-dark circle
Whitening
Collagen Germinating Peptide
Reforming Series
Regenerating Cream
Regenerating Eye Cream
De-mela Whitening Essence
Moisturizing and nourishing
Anti-atopic dermatitis
Hair-growth
Day by Day Revital Enery Series
MyAto Series
HairGenesis Series
Dermal-Delivery System technology (DDS)
Cellicon Lab applies Bio-encapsulation technology as a Dermal-Delivery System(DDS).
Bio-encapsulation is designed with bio-materials, so it shows great effect and safety without any side
effect.
Core Formulation
To maximize the efficacy of active ingredients, Cellicon Lab uses combination of natural products with
any other active ingredients and make a strong synergic effect and various formulation to satisfy
consumers’ needs.
R&D Field
Wrinkle&Firming
Anti-dark circle
Hair Growth
Collagen production
stimulating peptide
Melanin synthesis inhibiting
peptide
Scalp collagen production
promoting peptide
Anti-Acne
Anti-pollution
Anti-pigmentation
Anti-bactierial(P.acnes)
peptide
Protect skin against smoke
and heavy metals
Melanin synthetic hormone
inhibiting peptide
Atopic Dermatitis
Lypolysis
Anti-stretchmark
Skin regerating peptide
Lipolytic peptide
Melanin synthesis controlling peptide
Hair Growth
Pigmentation
Wrinkles&Firming
Dark circles
Anti-acne
AC Control Series
Patent
Peptide
Patent No
Whitening Peptide
10-1154233
Hair Growth Peptide
Acne
Atopic dermatitis
Stretchmarks
Pollution
Anti-wrinkle Peptide
10-15778901
Peptides for promoting hair growth, it’s synthetic procedure, and composition of
peptide to prevent hair loss or promote hair growth
10-1573745
Peptides for promoting synthesis of collagen, it’s synthetic procedure, and composition
10-2014-0113484
Lypolysis
Anti-acne
Atopic Dermatitis
Remarks
Grant
Grant
Grant
Cosmetic composition of acne treatment
Pending
10-20140113486
Cosmetic composition of treatment for skin trouble
Pending
10-2014-0113487
Peptide and amino acid complex for treatment of acne
Pending
10-2014-0113485
Cosmetic composition for prevention of atopic dermatitis
Pending
10-2014-0113488
Cosmetic composition for prevention of atopic dermatitis
Pending
10-2015-0168928
Cellicon Lab. Inc
Title
Cosmetic whitening composition containing tyrosine derivatives
Cosmetic composition containing β-glucan and peptide for skin reparing and
moisturizing
Pending
02+03
www.celliconlab.com
OEM / ODM
ODM / OEM
Active Ingredients
Cellicon Lab makes products for OEM/ODM based on new materials and core
formulation system in cooperation with domestic&international cosmetic companies.
Product Areas
High functional products
- Anti-aging, whitening, anti-trouble, anti-darkcircles, antioxidation
Cosmeceutical
- Atopic dermatitis, anti-acne, hair growth, anti-stretchmark, anti-pigmentation, anti-dark spots
Active Ingredients
Wrinkle free J316
WrinkleFree J316 is a new peptide that makes procollagen high-active which synthesize
collagen by fibroblasts. New anti-wrinkle and firming material which shows high activity in low
concentration (Patent No : 10-1573745)
Function
Anti-aging products
Formulation
Powder, water soluble
Specifications
Services
Various products and cost range
- Small/mass quantities
- Popular/targeted products
148% promote synthesis of collagen in 50 ppm concentration, low dermal toxicity
MTT assay
1.2000
Map
[3H]
Thymidine incorporation (% control)
Control
Pal-PNP-4
Pal-PN-4P
0.8000
120
CIL-J316
0.6000
80
0.4000
0.2000
40
0.0000
0
Optimized Business partner
10
100
500
1000
0
50 ug/ml
Concentration (uM)
- From popular products to targeted advanced products
- Bulk or finished product
Core Technology
Body-friendly ingredients applicable to skin concerns
- Peptide: Anti-acne, anti-pigmentation, anti-dark spots, anti-darkcircle, anti- atopic dermatitis,
anti-wrinkles, anti-stretchmark, hair growth
- β-glucan(93.3% purity), YeastzymeTM, natural extracts
Germinating Triplex
Core ingredients of WrinkleFree J316, Copper tripeptide-1 and amino acid complex that shows excellent
effect on anti-wrinkles, firming, moisturizing and regeneration.
Function
Stimulation of collagen, regeneration of damaged NMF
Application
Anti-wrinkles and nutrition
Formulation
Transparent liquid, water soluble
Specifications
Total solution from the ingredients to finished products
- Full skincare series, mask sheet
- Flexible production system based on various needs
- Finished and half-finished product
< MIN
AVG
> MAX
MOQ(kg)
< 100
300
> 500
Quantity(ea)
<1,000
3,000
> 5,000
120
100
80
O
O
Complex efficacy of anti-wrinkle, firming and moisturizing
[3H]
Thymidine incorporation (% control)
160
Collagen synthesis (%)
One Stop Service
Design Providing Negotiable
160
CIL-J316
1.0000
The latest and trendy products
- Based on investigation of concept and market research, we produce higher quality products
by develoing of formulation and packaging
Quote(%)
By stimulating collagen, enhance activity of dermal fibroblast
Application
Control
Pal-PNP-4
120
CIL-J316
80
40
0
10 ug/ml2
5 ug/ml5
- Competitive mass production cost
- Strict quality check
- Qulified formulation, production process and finished products
- ISO certified
Phospho-p38
Collagen type 1 a 1
Total p38
Collagen type 1 a 2
Phospho-ERK
Actin
Fast Production System
Guarantee on deadline of finished products within 45 days after order(except package and
design decision period)
Order - Consult - Contract - Development of product and sample test - Produce - QC - Delivery
0 ug/ml
Collagen synthesis study
CTL
No.1 No.2 No.3
50ppm
No.1 : Pal-PNP-4
No.2 : CIL-010
No.3 : CIL-J316
Total ERK
CTL
(ug/ml)
10 50
10 50
10 50
No.1
No.1
No.3
No.1 : Pal-PNP-4
No.2 : CIL-010
No.3 : CIL-J316
Business Process
Business consulting - Contract - Plan - Secrecy agreement - Sample test - Quotation Purchase order - Produce - QC - Delievery
Cellicon Lab. Inc
04+05
www.celliconlab.com
Acnotide(CIL-020)
Triple M Complex(CIL-060)
New anti-acne peptide that has excellent antimicrobial effect, directly sterilizing acne bacteria
(P.acnes), and antimicrobial mechanism without resistance against bacteria. 1000 times more
potent antimicrobial effect than existing peptide.
New skin-friendly and stable amino acid complex which has similar structure with Natural Moisturizing Factor(NMF).
Maintain the moisture balance on 18% even after 8 hours.
(Reference: Jamie, E.M. et al., J. Invest. Dermatol. (2005) 125, 256-263)
Function
Anti-acne, Anti-trouble
Application
Anti-acne cosmetics, anti-trouble cosmetics, after-treatment products
Formulation
Powder, water soluble
Moisturizing
Application
Skin regenerating product after cosmetic procedure,
cosmetics for dry skin
Formulation
Transparent liquid, water soluble
Recover moisture balance of skin, maintain 18% of
moisture balance after 8 hours
Specifications
1.00E+08
CIL-020
1.00E+06
1.00E+05
1.00E+04
Control
60
CIL-060(0.1%)
50
CIL-060(0.3%)
40
30
20
10
before
10
20
30
40
50
60
70
80
4hr
8hr
HairGenesis 1.1 (CIL-030)
Hydrophilic peptidoglycan layer
(lighter)
Cosmeceutical hair growth promoting peptide(Patent No: 10-15778901).
Since there is no link between HairGenesis 1.1 and testosterone, this peptide shows effectiveness for everyone.
0.5 um
0
2hr
Lipophilic layer (dark)
1.00E+03
1.00E+02
1hr
Untreated
Positive control
1.00E+07
70
0
Mechamism assay (ref.jamie et al)
Antimicrobial test
Bacterla remalning (CFU/ml)
Function
Electrical conductivity(A.U)
Active Ingredients
90 100
Peptide concentration (um)
Calm Triplex
Function
Hair growth, improving of scalp condition
Application
Hair loss prevention, scalp treatment
Formulation
Blue colored powder, water soluble
Specifications
Improving hair density and thickness
187%
142%
164%
0d
Calm Triplex is an anti-trouble ingredient which consists of two peptides and five amino acid
complex. It has strong soothing effect in low concentration, so it is fast-acting on acne problem.
122%
8w
4w
0d
Increase hair density
0d
Hair density (ea)
Hair thickness (mm)
8w
4w
Increase hair thickness
8w
4w
78
119
142
0.051
0.060
0.065
*. n : 12 (M ; 8 / f ; 4)
*. Ages : 59.5 yr. (ave.)
Function
Anti-trouble, Calming sensitive skin
Application
Anti-acne cosmetics, anti-trouble cosmetics
Formulation
Transparent liquid, water soluble
Specifications
Water, Copper Tripeptide-1, amino aicd complex
Hair growth test (in vivo)
β-glucan(93.3%)
Earn 93.7% of purity by enzyme fermentation technique.
Show effectiveness in moisturizing, anti-wrinkles and antioxidation.
Function
Anti-wrinkles, moisturizing
Application
Anti-aging series, moisturizing/nutrient series
Formulation
White colored powder
Comparison of ß-glucan purity
(left; 93%, right; ~40%
YeastzymeTM
Complex of β-glucan and natural fermentation ingredient. Excellent in moisturizing without sticky and greasy feeling.
Function
Anti-wrinkles, moisturizing
150
Application
Anti-aging series, moisturizing
100
Formulation
Water, β-glucan, Copper Tripeptide-1,
fermentated complex
Specifications
Transparent liquid, water soluble
Pro-collagen synthesis activity (%)
4
RT-PCR test of MMP-1 mRNA level
3
2
50
1
0
Negative
control
Positive control
(ascorbic acid
200ppm)
ß-glucan
50 ppm
ß-glucan
100 ppm
ß-glucan
200 ppm
0
60
control
ß-glucan
50 ppm
ß-glucan
100 ppm
66%
ß-glucan
200 ppm
0.5%HA
0.4%beta-glucan
244%
30
0
Cellicon Lab. Inc
20min
0.2%HA+0.3%beta-glucan
120min
06+07
www.celliconlab.com
PRODUCT
표준
Product Map
Wrinkles&Firming
Brand
C
a
t
e
g
o
r
y
Anti-acne
Whitening
Jeu’Demeure
Jeu’Demeure
Jeu’Demeure
Collagen Germinating
Day by Day
AC Control Series
Peptide Series
Revital Energy Series
Hair Loss
Atopic Dermatitis
Jeu’Demeure
HairGenesis Series
MyAto
Cleansing
Oil-free Cleanser
Toner
Reforming Toner
Mild Cleanser
Calming
Calming Gel
AcnoGel
Revital Toner
MyAto Lotion
Moisturizing
Reforming Cream
AcnoLotion
Revital Emulsion
MyAto Lotion
Revitallization
Reforming Ampoule
Reforming Cream
Special Care
V21 Solution
Jeu’Demeure
Collagen
Germinating
Peptide Series
(Anti-wrinkles
&Whitening)
Regenerating Shampoo
Regenerating Tonic
○ Freckles/Pigmentation
- De-mela Whitening Essence
Revital Energy Toner 150 ml
Revital Energy Emulsion 150 ml
The high-performance
formulation intensely nourishing
and refreshing. The most
purified β-glucan strengthen
skin’s moisture barrier.
Well-formulated emulsion with
patented ingredients helps skin
hydrate and repair damaged
skin.
Revital Energy Cream 50 ml
Revital Energy Mask 25 g
Freshly formulated for instant
moisturizing and hydrating.
High-content of premium
ingredients provide nourishment and revitalization.
Lightweight, non greasy and
non sticky.
Premium mask sheet with
purified β-glucan, maximize
the power of skin’s natural
recovery.
○ Dark circles
- Intensive Eye Cream
Regenerating Toner
Revital Cream
Intensive Care
Jeu’Demeure
Day by Day
Revital
Energy Series
(Moisturizing
&whitening)
MyAto Cream
○ Revitallization/Wrinkles
- Intensive Cream
○ Yellow&fine Dust
- DUST-OUT cleanser
○ Anti-mosquito
- MOS-OUT Body Wash
Oil-free Cleanser Milk
150 ml
Reforming Toner 200 ml
Oil-free cleanser without
foaming. No irritancy and
gentle removing makeup.
Make skin rest and smooth and
prepare the skin for the next
step of care.
Jeu’Demeure
Intensive Series
(Intensive Care)
De-mela Intensive
Whitening Essence
0.6 g + 12 ml
Brightening specialist with
patented De-mela complexTM.
The FRESHEST vitamin and
brightening peptide intensively
control melanin synthesis.
Cellicon Lab. Inc
Reforming Calming Gel
120 ml
V21 Solution 50 ml
Show great effect on skin
relaxing and soothe.
Recommend for sensitive
and troubled skin types.
Wash-off pack for lifting and
exfoliation. Make facial contours
strengthen and tighten.
Reforming Ampoule 30 ml
Reforming Cream 50 ml
Anti-wrinkle specialist with
high concentration of
peptide. Fine lines and
wrinkles around lips and
eyes effectively disappear.
Formulated with high concentration of peptide effectively
care wrinkle and fines.
Deliver moisture and rejuvenation on skin.
Intensive Regenerating
Cream 50 ml
Recover and regenerate
skin with concentrated
premium ingredients.
Also intensive nourishing
formula enhance elasticity
and firmness.
Intensive Regenerating
Eye Cream 30 ml
Premium eye contour cream.
Fine lines around eye area
disappear and get brighter with
peptide.
08+09
www.celliconlab.com
Product
Jeu’Demeure
AC Control Series
(Anti-acne)
Mild Cleanser 100 ml
Well-formulated cleanser
of skin-friendly pH level.
Suitable for acne and troubled skin types.
AcnoGel 60 ml
Show fast-acting improvement
on sensitive and acne-related
skin. Amino acid complex and
peptide effectively control
P.acnes instantly.
Jeu’Demeure
HairGenesis
Regenerating
Series
Hair Shampoo 250 ml
Hair Toner 150 ml
Perfectly free from harmful
ingredients and suitable for
troubled scalp.
NO PARABENS
NO SLS/SLES
NO SILICONS
Light toner for anti-hair loss
and troubled scalp.
Light formulation is suitable
for daily use.
Hair care product which helps
to improve scalp problems and
strengthen hair from roots to
ends.
AcnoLotion 60 ml
Hair Tonic 50 ml
The velvety lotion instantly
nourishes and soothes
without greasy.
MY ATO
Series
Cellicon Lab. Inc
Effective on hair loss and scalp
treatment with high concentration
of peptide.
Moist Lotion 150 ml
Intensive Cream 50 ml
Face and body lotion to
relieve the itching and
irritation of skin by
combination of 5 patented
ingredients.
High functional cream for
intensive care to strengthen
skin barrier. Restore
damaged skin and relieve
the itching.
Jeu’Demeure
OUT Series
DUST-OUT Foam Cleanser
150 ml
MOS-OUT Good Night Body Wash
320 ml
This is Jeu’Demeure solution
for anti-pollution. Premium
cleanser formulated with
Bio-Fiber which adsorbs fine
dust and heavy metals.
Anti-mosquito body wash
without irritant by including
natural antibactierial phytoncide
and natural extracts.
10+11