Part 2 - MIT Club of Washington DC

 INFECTIOUS DISEASES (ID) IRG Lead PIs:
Phase II Year 2
Jianzhu CHEN, MIT
OOI Eng Eong, Duke-NUS
Phase I: Jun 2007 to Dec 2013
Phase II: Jan 2013 to Dec 2017
Research Focus:
•  Understand pathogen-host interactions at the cellular and& molecular levels
•  Diseases worked on are influenza, RSV, dengue fever, malaria and tuberculosis
Highlights:
•  Developed an antibody that could potentially neutralize all four dengue serotypes
(worked in live mice tests)
•  Developed a set of biomarkers that could predict likelihood of getting DHF
27 EVIRONMENTAL SENSING AND MODELING CLIMATE URBAN ONLINE MONITORING & MODELING OF WATER DISTRIBUTION SYSTEM, HYDRAULICS & WATER QUALITY COUPLED MODELLING OF THE MARITIME CONTINENT REGIONAL CLIMATE MODELING OVER THE MARITIME CONTINENT NONPOINT SOURCE WATER QUALITY IN SINGAPORE’S CATCHMENTS ECOLOGICAL GENOMIC INDICATORS FOR URBAN WATER QUALITY MARINE WAVE-­‐CURRENT-­‐SEDIMENT INTERACTION FACILITY DYNAMICS OF SEDIMENT CLOUDS NEAR FIELD HYDRODYNAMICS SENSORS and OPTICAL VERIFICATION GLOBAL CLIMATE MODELING AND PROCESSES PEAT FOREST FLUXES AND CARBON FOOTPRINT URBAN CARBON FLUXES AND ABSORPTION BY VEGETATION HIGH RESOLUTION MULTI-­‐SCALE MODEL OF SINGAPORE ENVIRONMENT ROBOTIC FLEET FOR ENVIRONMENTAL MONITORING AND INSPECTION IN-­‐SITU CHEMICAL SENSING FOR ENVIRONMENTAL MONITORING CENTER FOR ENVIRONMENTAL SENSING AND MODELING (CENSAM) IRG Lead PI:
Leslie NORFORD, MIT
Phase II Year 1
Phase I: Jan 2008 to Dec 2012
Phase II: Jan 2013 to Dec 2017
Research Focus:
• 
To develop a representation of the natural and built environment that will seamlessly transition from micro-scale processes, to the
meso-scale of the citystate of Singapore
• 
Develop new environmental sensor technology, networks & platforms and predictive environmental models
• 
Demonstrate the importance of pervasive sensing through applications in the well managed urban environment of Singapore
Highlights:
• 
Developed WaterWise@SG software platform for real-time monitoring of water distribution network in Singapore in collaboration with
PUB
• 
Efforts to discover through corals why there is an unusual type of lead content found in the sea around Singapore
• 
Development of low-cost multi-platform sensors to potentially improve the efficiency and accuracy of monitoring water quality
• 
Researcher concluded the type of tree plant is a significant factor in reducing emissions
29 BIOSYSTEMS AND MICROMECHANICS Imaging
Microfluidics
Cell sorting / profiling
Computation &
Control
Stalk Cell
Tip Cell
Lumen
Filopodia
Single molecule handle
Bio-Physics
small MSCs large MSCs
unsorted
psg 3 MSCs
D7
D14
Cancer drug screening
High%
Cancer proliferation in the absence of drug
D7 D14
High% Low%
hMSCs angiosense
Low%
Cancer proliferation arrested by drug
Stem Cells & tissue
Liver fibrosis multiengineering
Point of care diagnostics
scale imaging
30 BIOSYSTEMS AND MICROMECHANICS (BioSyM) IRG Lead PI:
Krystyn VAN VLIET
Phase II Year 1
Phase I: Jan 2009 to Dec 2013
Phase II: Jan 2014 to Dec 2018
Research Focus:
•  Mechanics-based technologies to understand, detect, and treat tissue diseases and
regenerate healthy tissues
•  Developed cutting-edge engineering technologies for molecular-scale to tissue-scale
discoveries and diagnostics
Noteworthy:
•  Developed a patent pending circulating tumor cells (CTC) isolation and retrieval technique
which has been acquired by Clearbridge Biomedics
•  Developed a palm-sized NMR-based biosensor for point-of-care medical diagnosis
31 FUTURE URBAN MOBILITY Technologists Wireless Traffic Network Autonomy Transport Systems Modelers Planners Travel Behavior Models (LT/MT/ST) Infrastructure Measure. Real-­‐Time Traffic Mgt FM = Technologists + Modelers + Planners Social Accessibility Modelers CongesIon-­‐Aware RouIng Mobility-­‐on-­‐Demand Trip Ahractors & Producers Technologists Boarding AlighXng Real-­‐Time Data Plaform & ApplicaIons Path Track & Route Guidance FM Planners Urban Metabolism 32 FUTURE URBAN MOBILITY (FM) IRG Lead PI:
Emilio FRAZZOLI, MIT
Phase I Year 4
Phase I: Jul 2010 to Jun 2015
Research Focus:
•  Use combination of new technologies and optimized operations management to
maximize productivity of existing infrastructure, improve level of service and
enhance sustainability of urban mobility.
Highlights:
•  Currently working on demonstrating safe, reliable low cost autonomous driving
capabilities on the NUS campus
•  Low cost crowd counting using audio tones
33 ENERGY ELECTRONIC SYSTEMS LOW To create new materials, devices, and integrated circuits that offer new funcXonality, lower power, and increased miniaturizaXon as compared to current electronic systems MulXfuncXonal Displays Self-­‐Powered Systems material Efficient CommunicaXons process Power Electronic Systems chip III -­‐ V template
Si substrate
GaAsP
Si0.30Ge0.70
500 nm
12 LOW ENERGY ELECTRONIC SYSTEMS (LEES) IRG Lead PIs:
Eugene FITZGERALD, MIT
YOON Soon Fatt, NTU
Phase I Year 3
Phase I: Jan 2012 to Dec 2016
Research Focus:
•  More efficient use of power in integrated electronics
•  Identify new technologies in seminconductor electronic systems with reduced
energy per function, lower power consumption and higher performance electronic
infrastructure
Highlights:
•  Collaborative agreements signed with Aixtron, EVG and SAMCO
•  GlobalFoundries and Panasonic Jazz Tower as a commercial foundry partners
35 INNOVATION EvoluIon of aC
n ENTRE Idea Catalysts i-­‐Teams NUS, NTU, INSEAD, SMU Bootcamp Ideas Emerge from Basic Research SELECT (review by VCs and Entrepreneurs) DIRECT (Catalysts, iTeams, Bootcamps) CONNECT (to Markets and Financing) New Company FormaXon Company Growth InvenIon disclosures = 84 Under licensing opIon = 4 (13 technologies) Under license = 4 Start-­‐up companies = 13 Networking Events/IdeaStream Applicants from MIT-SMART and throughout Singapore.
14 13 START-­‐UPs FORMED 13 START-­‐UPs FORMED PHD PROGRAM  MOE Funding
 Total of 10 intakes (2 per year)
 Awarded a total of 75 fellowships
 NUS: 44; NTU: 31
 SMART Funding
 BioSyM:
 BioSyM:
Awarded 25; Accepted 15
 1st intake: August 2014
 Awarded 19; Accepted 9
 NUS: 5; NTU: 4
Awarded 3; Accepted 2
 CENSAM: Awarded 28; Accepted 20
 CENSAM: Awarded 4; Accepted 2
 FM:
Awarded 13; Accepted 10
 FM:
Awarded 3; Accepted 1
 ID:
Awarded 23; Accepted 18
 ID:
Awarded 4; Accepted 1
 LEES:
Awarded 19; Accepted 12
 LEES:
Awarded 5; Accepted 3
39 SMURFS (MIT, NUS and NTU) SUMMER UGs Students
•  Opportunity for an International
Experience
Singapore-­‐MIT Undergraduate Research Fellows (SMURFs) Summer 2014 Summer 2013 •  Exposure to different cultures
•  Increase personnel self-development,
self-confidence, and maturity
•  Make new friends
•  Opportunity to learn a new language
•  Enhance employment prospects as
employers value international
experience
•  Opportunity to travel within the region
SMART’s Birthday CelebraIon: SMURFs on stage 40 STRATEGIC DIRECTIONS External Growth – Position for the Future
§  Strengthen the CREATE and Singapore University interactions
§  Diversify the research base (Expand out from the current base but
within the IRG concept)
§  Deepen the two-way flow of people and ideas with MIT
Internal Alignment – Continuous Improvement
§  Build the SMART community
§  Develop the SMART brand in Singapore, at MIT and to the world
41 THANK YOU hhp://smart.mit.edu