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Volume 377 · Number 9769 · March 12–18, 2011 The Lancet—London 32 Jamestown Road, London NW1 7BY, UK T +44 (0)20 7424 4910 F +44 (0)20 7424 4911 The Lancet—New York 360 Park Avenue South, New York, NY 10010–1710, USA T +1 212 633 3810 F +1 212 633 3853 Editorial Articles 875 876 876 905 A breath of fresh air please “A very severe physical trial” Preventing elder abuse: can we learn from child protection? Comment P Malfertheiner and others 877 Quadruple or triple therapy to eradicate H pylori 914 The Lancet—Beijing Unit 1–6, 7F, Tower W1, Oriental Plaza, Beijing 100738 China T + 86 10 85208872 F + 86 10 85189297 878 EMBRACE, eribulin, and new realities of advanced breast cancer editorial@lancet.com Editor Richard Horton Deputy Editor Astrid James Senior Executive Editor Sabine Kleinert Executive Editors Pam Das Justine Davies David McNamee Ros Osmond Pia Pini Stuart Spencer William Summerskill Managing Editor Stephanie Clark Web Editors Richard Lane Erika Niesner Assistant Web Editor Nicolai Humphreys 880 Ultra-long-acting insulins for a lifestyle-related pandemic J Monsonego 883 Universal health care in India: missing core determinants R Narayan 885 A stormy future for population health in southeast Asia? C D Butler B Zinman and others 932 Incidence and clearance of genital human papillomavirus infection in men (HIM): a cohort study A R Giuliano and others Clinical Picture 941 Retroperitoneal liposarcoma with lamellar bone inside J Yamauchi and others Seminar 888 Offline: Where are the optimists? G-Z Yang and others R Horton World Report 889 US bioethics commission hears expert testimonies N Bristol 890 Mediator scandal rocks French medical community A Mullard M C Kiernan and others 956 The health of prisoners S Fazel, J Baillargeon Case Report 966 Rupture without warning S Schimmack and others Perspectives 893 Seamus Heaney—digging deep into prehistory R Tallis 894 In brief A Robinson 895 On Reflection J Laurance 895 Lunch with The Lancet C Martin 896 Virtue and vice in health and illness: the idea that wouldn’t die R P Sloan Deputy Managing Editor Hannah Cumber Obituary Senior Assistant Editors Laura Benham David Holmes Katrina Phillips Onisillos Sekkides Lucy Wilkie Farhat Yaqub 898 Herschel Weldon Leibowitz Assistant Editors Olaya Astudillo Mario Christodoulou Tim Dehnel Jessica Greatrex Dara Mohammadi Zena Nyakoojo L Frölich, H Förstl; A-C J M de Pont and others; D Gusmao-Flores and others; R M G Berg, K Møller; F L Opdam and others; M M J van Eijk and others 901 New drug development 903 Benefits of medical treatment of obesity 903 What would Shaw do? 903 The dynamics of collective human behaviour The Lancet® is a registered trademark of Elsevier Properties S A, used under licence. Review Editorial Assistants Holly Baker Emma Rogulska Katherine Rolfe Frances Whinder J Cortes and others 924 Insulin degludec, an ultra-long-acting basal insulin, once a day or three times a week versus insulin glargine once a day in patients with type 2 diabetes: a 16-week, randomised, open-label, phase 2 trial 942 Amyotrophic lateral sclerosis Asia Editor Helena Hui Wang (Beijing) Media Relations Manager Tony Kirby Eribulin monotherapy versus treatment of physician’s choice in patients with metastatic breast cancer (EMBRACE): a phase 3 open-label randomised study 886 Patients’ safety for global health Conference Editor Laura Hart Elvira Manjaji Y C Kudva, A Basu 881 Genital infection with HPV in men: research into practice Senior Editors Niall Boyce Jane Godsland Lin Guo Seema Kang Selina Lo Zoë Mullan Joanna Palmer Udani Samarasekera Richard Turner North American Senior Editor Maja Zecevic (New York) B H Lee, N Kim N U Lin, H J Burstein Helicobacter pylori eradication with a capsule containing bismuth subcitrate potassium, metronidazole, and tetracycline given with omeprazole versus clarithromycin-based triple therapy: a randomised, open-label, non-inferiority, phase 3 trial S Pincock Correspondence 899 Cholinesterase inhibitor treatment in patients with delirium S J Hoffman and others; F Catalá-López and others P Aveyard S A Norton J Krause, G D Ruxton 904 No increased risk of febrile convulsions after seasonal influenza immunisation in UK P Bryan, S Seabroke 904 Department of Error Peer reviewed and fast-tracked to publication in 4 weeks Previously published online See www.thelancet.com for WebExtra content International Advisory Board Karen Antman (Boston) Valerie Beral (Oxford) Robert Beaglehole (Auckland) Anthony Costello (London) Robert Fletcher (Boston) Suzanne Fletcher (Boston) Karen Gelmon (Vancouver) David Grimes (Durham) Ana Langer (Mexico City) Judith Lumley (Melbourne) Elizabeth Molyneux (Blantyre) Christopher Murray (Seattle) Alwyn Mwinga (Lusaka) Marie-Louise Newell (Somkhele) Magne Nylenna (Oslo) Peter Piot (London) Stuart Pocock (London) Giuseppe Remuzzi (Bergamo) Caroline Savage (Birmingham) Ken Schulz (Chapel Hill) Frank Shann (Melbourne) Jan Vandenbroucke (Leiden) Cesar Victora (Pelotas) Nick White (Bangkok) Information for Authors See www.thelancet.com for guidelines for authors. Ombudsman Charles Warlow (c/o The Lancet or ombudsman@lancet.com)