Scientific Programme Wednesday 14th

Scientific Programme
Wednesday 14th
12.00-18.30 Registration
15.00-17.00 Educacional Symposium: UPDATE ON THROMBOSIS 2014 (Auditorium 2)
Chairs: Javier Batlle, Spain; Ismaïl Elalamy, France
1. Antiphospholipid syndrome: From pathogenesis to novel immunomodulatory therapies
Patrice Cacoub, France
2. Bleeding management of patients under antithrombotic therapy José A. Páramo, Spain
3. Laboratory Monitoring of anticoagulant drugs. Problems and solutions
Armando Tripodi, Italia
4. Heparins in 21st century Ismaïl Elalamy, France
17.00-18.30 Satellite Symposium: FERMENTED BEVERAGES AND MEDITERRANEAN DIET (Auditorium 2) Chairs: Lina Badimon, Spain; Juan José Badimon, USA 18.30
1. Introduction Lina Badimon, Spain 2. Beer in Cardiovascular Health Gemma Vilahur, Spain 3. Wine in Cardiovascular Health Maria Benedetta Donati, Italy 4. PREDIMED Study Ramón Estruch, Spain 5. Concluding remarks and discussion Juan José Badimon, USA Opening Ceremony
Thursday 15th
08.30-09.30 State of Art Session: CHALLENGES IN HAEMOSTASIS AND THROMBOSIS (Auditorium 1)
Chairs: Lina Badimon, Spain; Mª Teresa Santos, Spain
MicroRNAs in thrombosis and haemostasis Manuel Mayr, United Kingdom
The VWF and ADAMTS13 axis: from mechanisms to cardiovascular importance David Lane, United Kingdom
09.40-10.40 Oral Communications (OC1, OC2, OC3, OC4, OC5)
OC1: DEEP VEIN THROMBOSIS: EPIDEMIOLOGY AND RISK FACTORS (Auditorium 2)
Chairs: Harry R. Buller, The Netherlands; Essam AboelNazar, Saudi Arabia
C-0025 THE IMPACT OF RESIDUAL THROMBOSIS ON THE OUTCOME OF PATIENTS WITH DEEP-VEIN THROMBOSIS
Paolo Prandoni; Anthoine WA Lensing; Martin H Prins; Franco Noventa; Sabina Villalta
C-0116 FUNCTIONAL ANALYSIS OF TWO HAPLOTYPES OF THE HUMAN ENDOTHELIAL PROTEIN C RECEPTOR GENE (PROCR)
Elena Bonet, Laura Martos, Luis A. Ramón, Fernando Ferrando, Amparo Vayá, Yolanda Mira, Santiago Bonanad, Amparo Estellés,
Rogier M. Bertina, Hans L. Vos, Francisco España, Pilar Medina, Silvia Navarro Rosales
C-0119 SUBSEQUENT ARTERIAL EVENTS IN PATIENTS WITH ACUTE VENOUS THROMBOEMBOLISM. FINDINGS FROM THE RIETE REGISTRY.
Olga Madridano Cobo, Paolo Prandoni, Jorge del Toro, Alicia Hernández, Mar Martín del pozo, Jorge Gómez Cerezo, Dolores Nauffal, Luis
Hernández, José Bascuñana, Manel Monreal
C-0432 THE RISK OF VENOUS THROMBOSIS IN PATIENTS WITH ULCERATIVE COLITIS
Tetyana Ternushchak, Ivan Chopey, Olga Ternushchak, Michajlo Ternushchak, Vasil Ploskina
C-0463 A CLINICAL SCORE TO RULE OUT THE CONCOMITANT PRESENCE OF DEEP VEIN THROMBOSIS IN PATIENTS PRESENTING WITH SUPERFICIAL VEIN THROMBOSIS : THE ICARO STUDY
Francesco Dentali, Fulvio Pomero, Matteo Nicola Dario Di Minno, Eleonora Tamburini Premunian, Alessandra Malato,
Samantha Pasca, Giovanni Barillari, Luigi Fenoglio, Sergio Siragusa, Giovanni Di Minno, Walter Ageno
C-0525 LONG-TERM RECURRENCE OF VENOUS THROMBOEMBOLISM AFTER TREATED SYMPTOMATIC DISTAL VEIN THROMBOSIS: A RETROSPECTIVE COHORT STUDY
Marco Donadini, Francesco Dentali, Samuela Pegoraro, Fulvio Pomero, Chiara Brignone, Luigina Guasti, Luigi Steidl, Walter Ageno
OC2: NEW APPROACHES AND TECHNOLOGIES TO UNDERSTAND THROMBOSIS IN CORONARY ARTERY DISEASE (Auditorium 3)
Chairs: Turgut Ulutin, Turkey; Gemma Vilahur, Spain
C-0225 PROFILIN-1 LEVELS IN CORONARY THROMBUS AND SYSTEMIC BLOOD DETERMINE PAIN-TO-PCI ELAPSED TIME IN STEMI-PATIENTS
Ilaria Ramaiola, Teresa Padró, Esther Peña, Oriol Juan-Babot, Victoria Martin, Salvatore Brugaletta, Manel Sabaté, Lina Badimon
C-0229 MUTATIONS CREATING NEW GLYCOSYLATION SITES CAUSE DIFFERENT TYPES OF ANTITHROMBIN DEFICIENCY. ROLE OF AN N-GLYCAN AT
THE REACTIVE CENTRE LOOP.
Sonia Aguila, Irene Martínez-Martínez, Nataliya Bohdan, María Eugenia de la Morena-Barrio, Vicente Vicente, Javier Corral
C-0430 THROMBUS PROTEOMIC PROFILE IN STENT-THROMBOSIS
Ilaria Ramaiola, Judit Cubedo, Teresa Padró, Ana Blasco, Javier Goicolea, Lina Badimon
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C-0289 IDENTIFICATION OF A MICROVESICLE PROTEIN NETWORK RELATED TO INFLAMMATORY RESPONSE AND CARDIOVASCULAR DISEASE
THAT PLAYS A RELEVANT ROLE IN ST-ELEVATION MYOCARDIAL INFARCTION
Paula Vélez Viéitez, Raymundo Ocaranza-Sánchez, Andrés F. Parguiña, Lilian Grigorian-Shamagian, Isaac Rosa, Sergio Alonso-Orgaz, Fernando de la Cuesta, José Moreu, María G. Barderas, José Ramón González-Juanatey, Ángel García
C-0398 ACTIVATED FACTOR VII-ANTITHROMBIN COMPLEX PLASMA CONCENTRATION IS A PREDICTOR OF TOTAL AND CARDIOVASCULAR
MORTALITY IN PATIENTS WITH CORONARY ARTERY DISEASE AND ITS PROGNOSTIC SIGNIFICANCE IS IMPROVED BY USING FACTOR VII
GENOTYPE-SPECIFIC THRESHOLD LEVELS
Nicola Martinelli, Domenico Girelli, Marcello Baroni, Patrizia Guarini, Federica Tosi, Barbara Lunghi, Barry Woodhams,
Francesco Bernardi, Oliviero Olivieri
C-0076 INTERACTION BETWEEN HYPERTENSION AND FIBRINOGEN GENETIC VARIABILITY IN PATIENTS ADMITTED FOR STABLE ANGINA PECTORIS SYMPTOMS: EFFECTS ON INFLAMMATION AND COAGULATION
Zoi Pallantza, Nikolaos Papageorgiou, Dimitrios Tousoulis, Vaso Palioura, Argiri Vlachopoulou, Athanasios Bramos, Christos Tassos,
Olga Zoupouli, Stavros Kontos, Christodoulos Stefanadis
OC3: THROMBOSIS AND HAEMOSTASIS IN WOMEN (Room 1)
Chairs: Aitana Braza, Spain; Elvira Grandone, Italy
C-0155 SPANISH REGISTRY OF THROMBOEMBOLIC DISEASE (TD) RELATED WITH HORMONAL THERAPY, PREGNANCY, OBSTETRICS COMPLICATIONS OR ASSISTED REPRODUCTIVE TECHNIQUES IN WOMEN (ARP): PRELIMINARY RESULTS OF THE TEAM PROJECT.(TROMBOSIS EN EL
ÁMBITO DE LA MUJER)
A. Redondo-Izal, I. de Diego, A. Rodriguez-Huertas, P. LLamas, FJ. Rodriguez-Martorell, Oscar Martinez, Manel Casellas, Dolors Tássies, Amparo Santamaria, I.M. Ramirez, M.J. Gutierrez-Pimentel
C-0527 CIRCULATING PROCOAGULANT CELL-DERIVED MICROPARTICLES IN WOMEN WITH RECURRENT MISCARRIAGE ASSOCIATED WITH THE
ANTIPHOSPHOLIPID SYNDROME
D Tassies, L Martin, MA Martinez-Zamora, E Garcia, J Monteagudo, M Creus, F Carmona, J Balasch, JC Reverter
C-0292 THE ROLE OF BREAST CANCER CELL MICROPARTICLES IN THROMBOGENICITY, ANGIOGENESIS AND APOPTOSIS FOLLOWING CHEMOTHERAPY
Anat Aharon; Benjamin Brenner; Gil Barsela; David Loven
C-0390 PREGNANCY RELATED VENOUS THROMBOEMBOLISM: COMPARISON BETWEEN SPONTANEOUS AND ART CONCEPTION
Michela Villani ; Giovanni Tiscia ; Donatella Colaizzo ; Tiziana Petruccelli ; Saverio Fusilli ; Natale Sciannam ; Francesco Petruzzelli ; Pantaleo Greco ;
Maurizio Margaglione ; Elvira Grandone
C-0483 ”OESTROGENS DOWNREGULATE TFPI EXPRESSION THROUGH DIRECT INTERACTION AND INHIBITION OF ITS PROMOTER ACTIVITY\”
Huda Omar Ali; Benedicte Stavik; Elisabeth Dørum; Christiane Myklebust; Nina Iversen; Per Morten Sandset; Grethe Skretting
C-0575 GUIDELINES FOR THE PREVENTION OF ARTERIAL AND VENOUS THROMBOSIS DURING ASSISTED REPRODUCTIVE TECHNOLOGIES.
Jacqueline Conard; J Belaisch-Allart; H Creusvaux; JP Galanaud; C Lamy; S Laporte; L Larue; F Merlet; D Mottier; A Pariente-Khayat;
G Plu-Bureau
OC4: THERAPEUTIC APPROACHES TARGETING PLATELETS, THROMBOSIS AND HAEMOSTASIS (Room 3)
Chairs: Gines Escolar, Spain; Antonio Moscardó, Spain
C-0252 BLOCKADE OF ADP-RECEPTOR WITH TICAGRELOR IN PENTRAXIN-INDUCED PLATELET DEPOSITION
Esther Peña, Raquel De la Torre, Gemma Vilahur, Lina Badimon
C-0368 EFFECT OF TICAGRELOR VERSUS CLOPIDOGREL ON DYNAMIC PLATELET ADHESION IN PATIENTS WITH AN ACUTE CORONARY SYNDROME
Maria Tsoumani, Prokopia Tatsidou, Ioannis Ntalas, Kallirroi Kalantzi, John Goudevenos, Alexandros Tselepis
C-0426 PARTIAL INHIBITION OF PLATELET THROMBOXANE A2 SYNTHESIS AT THE EARLY ONSET OF ACUTE MYOCARDIAL INFARCTION IS ASSOCIATED WITH CARDIAC DEATH AT ONE YEAR FOLLOW-UP.
Isabel Madrid; Antonio Moscardó; Maria Paz Fuset; Luis María De Hevia; Ana Latorre; Juan Bonastre; Miguel Ruano;
Maria Teresa Santos; Juana Vallés
C-0417 BLEEDING PROPENSITY BY TICAGRELOR AND CLOPIDOGREL AT SIMILAR INHIBITION OF PLATELET AGGREGATION IN A CONSCIOUS PIG
MODEL
Gemma Vilahur, Lina Badimon
C-0539 THE PROTHROMBOTIC PROFILE OF BCR-ABL INHIBITORS PONATINIB, NILOTINIB, AND IMATINIB
Cassandra P. Loren, Rachel A. Rigg, Joseph E. Aslan, Laura D. Healy, Andras Gruber, Owen J.T. McCarty
C-0490 ROLE OF PLATELET PROTEIN S IN PRIMARY HAEMOSTASIS IN MICE
Begoña Hurtado, Tal Burstyn-Cohen, Ginés Escolar, Greg Lemke, Pablo García de Frutos
OC5: PLATELETS AND THROMBOSIS IN CHILDREN (Room 6)
Chairs: Patricia Massicotte, Canada; Ana Bronic, Croatia
C-0532 NOVEL MUTATIONS IN THE GAMMA CARBOXYLASE GENE CAUSING VKCFD1
M. Ángeles Dasí, Rocío González-Conejero, Sara Izquierdo, José Padilla, Bienvenida Argilés, Javier Corral
C-0403 GENE EXPRESSION DIFFERENCES BETWEEN NEONATAL AND ADULT PLATELETS: NEW POTENTIAL MODULATORS OF HUMAN PLATELET
REACTIVITY
E Caparrós-Pérez, R Teruel-Montoya, JM Torregrosa, JL Delgado2, MC Llanos, J Rivera, R González-Conejero, V Vicente,
C Martínez, F Ferrer-Marín
C-0405 ROLE OF SYNTAXIN-11 IN GRANULE RELEASE OF NEONATAL PLATELETS.
E Caparrós-Pérez, R Teruel-Montoya, JL Delgado, JM Torregrosa, F Navarro, N Montoya, J Rivera, MC Llanos, V Vicente, C Martínez,
F Ferrer-Marín
C-0414 PREVALENCE OF HYPERHOMOCYSTEINEMIA AND ITS ASSOCIATION WITH C677T MTHFR POLYMORPHISM, VITAMIN B12 AND FOLATE
LEVELS IN CROATIAN CHILDREN WITH CEREBROVASCULAR ACCIDENTS
Jasna Lenicek Krleza, Duranovic Vlasta, Vlatka Mejaski Bosnjak, Lucija Lujic, Ana Bronic
C-0475 CEREBRAL SINUS VENOUS THROMBOSIS IN CHILDREN: AN EMERGENT DISEASE
Sara Izquierdo Sebastiá; Bienvenida Argilés Aparicio; M. Ángeles Dasí Carpio
C-0326 POLYMORPHISMS IN COAGULATION FACTOR GENES AND ENZYMES OF HOMOCYSTEINE METABOLISM IN CROATIAN CHILDREN WITH
ARTERIAL ISCHEMIC STROKE
Desiree Coen Herak, Jasna Lenicek Krleza, Margareta Radic Antolic, Ivana Horvat, Vlasta Djuranovic, Renata Zrinski-Topic, Renata Zadro
10.45-11.15 Coffee Break
11.30-13.00 Symposium: IMPLICATIONS OF THROMBOSIS IN THE EVOLUTION OF VASCULAR DISEASE (Auditorium 1)
Chairs: Juan José Badimon, Spain; Jose A. Páramo, Spain 1. Role of tissue factor in endothelial and vascular smooth muscle cell function Agneta Sieghbhan, Sweden 13
2. The role of platelets in vascular integrity in the context of inflammation. Steve Watson, United Kingdom
3. Thrombosis as an intravascular effector of innate immunity. Bernd Engelmann, Germany Symposium: HAEMOSTASIS AND THROMBOSIS IN WOMEN (Auditorium 2)
Chairs: Benjamin Brenner, Israel; Amparo Estelles, Spain 1. Thrombosis, thrombophilia, vascular complications and antithrombotic therapy in pregnancy
Ian A Greer, United Kingdom
2. Antithrombotic prophylaxis and Assisted reproduction techniques Elvira Grandone, Italy
3. Fibrinolysis and angiogenesis in gynaecological pathology Juan Gilabert-Estelles, Spain
13.15-14.45 Educational Symposium ICCC: UPDATE ON THE TREATMENT OF PATIENTS WITH CORONARY ARTERY
DISEASE (Auditorium 2) This symposium is possible thanks to an unrestricted grant from:
Chairs: Lina Badimon, Spain; Jose Luis López-Sendón, Spain 1. Introduction Lina Badimon, Spain 2. New Modulators of Platelet Activation Juan José Badimon, USA 3. From Plato to clinical experience with Ticagrelor: Clinical efficacy and ESC guidelines recommendations
Antonio Fernández-Ortiz, Spain 4. Ticagrelor: Clinical safety and off-target effects? Robert F. Storey, United Kingdom 5. Concluding remarks and discussion José Luis López-Sendón, Spain
13.15-14.45 OPTIMIZING PATIENT PROTECTION FROM THROMBOEMBOLIC DISEASE: PRACTICAL GUIDANCE ON THE
USE OF DABIGATRAN ETEXILATE(Auditorium 3)
Chairs: David Jiménez Castro, Spain
1. Welcome and introduction
David Jiménez Castro, Spain
2. Protecting patients with nonvalvular atrial fibrillation from ischaemic stroke: the importance of optimal
anticoagulation
Menno Huisman, The Netherlands
3. Periprocedural and emergency management of patients receiving dabigatran etexilate: A case-based
approach
Ismaïl Elalamy, France
4. New horizons for dabigatran etexilate in thromboembolic disease
Peter Verhamme, Belgium
5. Panel discussion and closing summary
David Jiménez Castro, Spain
13.15-14.45 Lunch
15.00-16.30 Symposium: CROSSTALK-MECHANISMS BY MICROPARTICLES IN THROMBOSIS (Auditorium 1)
Chairs: Joan Montaner, Spain; Rienk Nieuwland, The Netherlands
1. Circulating microparticles Rienk Nieuwland, The Netherlands 2. Platelet/monocyte microparticles in cell to cell communication Gemma Vilahur, Spain
3. The role of platelets and their microparticles in rehabilitation of ischemic brain tissue
David Varon, Israel Symposium: THROMBOSIS IN CHILDREN (Auditorium 2)
Chairs: Maria Angeles Dasí, Spain; Gili Kenet, Israel 1. Inherited thrombophilia in children. What’s new? Ulrike Nowak, Germany 2. Thrombosis & Brain. Management of venous and arterial thrombosis in children
Gili Kenet, Israel
3.- Thrombosis & Heart. News in pediatric anticoagulation and antiaggregation M. Patricia Massicotte, Canada
16.40-17.20 Poster session Coffee
17.30-19.00 Symposium: ADVANCES IN UNDERSTANDING PLATELET FUNCTION: MOLECULAR APPROACHES (Auditorium 1)
Chairs:Steve Watson, United Kingdom; Juana Vallés, Spain 1. GPVI signaling in platelet function: clinical and pharmacological implications. Martine Jandrot-Perrus, France
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2. Mechanisms involved in the platelet procoagulant activity Johan W. M. Heemskerk, The Netherlands
3. Understanding reticulum endoplasmic proteins in platelet function. Teresa Padró, Spain Symposium: TREATMENT OF VENOUS THROMBOEMBOLISM (Auditorium 2)
Chairs: Paolo Prandoni, Italy; Ramon Lecumberri, Spain 1. Optimal duration of treatment of venous thrombosis. Paolo Prandoni, Italy
2. Optimal duration of prophylaxis of postoperative venous thrombosis Juan Ignacio Arcelus, Spain 3. Role of the new drugs for maintaining anticoagulant therapy. Harry R. Büller , Netherlands
Friday 16th
State of Art Session: BLOCKING THROMBOSIS IN INTERVENTIONAL PROCEDURES: THE KEY TO SUCCESS (Auditorium 1)
Chairs:Pier Manucci, Italy; Vicente Vicente, Spain Reducing the burden of thrombosis in interventional cardiology Manel Sabaté, Spain Thromboembolism in surgery
Ola E. Dahl, Norway
09:40-10:40 Oral Communications
08.30-9.30
OC1: VTE AND PE (Auditorium 2)
Chairs: Armando d’Angelo, Italy; Juan Carlos Reverter, Spain
C-0523 VENOUS THROMBOEMBOLISM IN SPECIAL POPULATIONS-FINDINGS FROM THE RIETE REGISTRY
Emmanouil Papadakis Dionysia Theocharidou; Constantina Skarmoutsou-Tsimirika; T. Bueso; D. Babalis; A. Braester; Eirini Baldoumi; Anna Kioumi; Manuel
Monreal-Bosch
C-0304 BEMIPARIN PHARMACODYNAMICS/PHARMACOKINETICS IN YOUNG, ELDERLY AND SUBJECTS WITH RENAL IMPAIRMENT
Javier Martínez-González, Salvador Rico, María Rosa Ballester, Ibon Gutierro, Montserrat Borrell, Ignacio Ayani,
Rosa-María Antonijoan, Ignasi Gich, Jordi Fontcuberta
C-0442 POOR PREDICTIVE VALUE OF CONTEMPORARY BLEEDING RISK SCORES DURING LONG-TERM TREATMENT OF VENOUS THROMBOEMBOLISM: A MULTICENTER RETROSPECTIVE COHORT STUDY
Francesco Dentali, Nicoletta Riva, Matteo Nicola Dario Di minno, Nicola Mumoli, Fulvio Pomero, Massimo Franchini, Chiara Fantoni, Roberta Lupoli,
Barbara Brondi3, Valentina Borretta4, Carlo Bonfanti, Walter Ageno
C-0259 PREVALENCE OF DEEP VENOUS THROMBOSIS USING BILATERAL LEG ULTRASOUND IN HOSPITALIZED PATIENTS EVALUATED FOR PULMONARY EMBOLISM? A PRELIMINARY REPORT
María Lourdes Posadas Martínez, Diego Giunta, Sebastian Sevilla, Diego Giunta, Fernan Bernaldo de Quiros, Esteban Gandara,
Vanesa Cubilla, Fernando VAzquez
C-0255 IMMEDIATE AND LONG TERM MORTALITY IN PATIENTS WITH SUSPECTED PULMONARY EMBOLISM: PROSPECTIVE COHORT IN ARGENTINA
Maria-Lourdes Posadas Martinez, Maria Laura Martin, Fernan González Bernaldo de Quirós, Diego Giunta, Fernando Vazquez
C-0197 OPTIMIZATION OF THE DIAGNOSTIC MANAGEMENT OF CLINICALLY SUSPECTED PULMONARY EMBOLISM IN HOSPITALIZED PATIENTS
Tom van der Hulle, Paul den Exter, Inge Mos, Peter Kamphuisen, Marcel Hovens, Marieke Kruip, Josien van Es, Hugo ten Cate, Menno Huisman, Erik Klok
OC2: CANCER AND THROMBOSIS (Auditorium 3)
Chairs: Giancarlo Agnelli, Italy; Dolores Tássies, Spain
C-0271 INCIDENTAL VERSUS SYMPTOMATIC PULMONARY EMBOLISM (PE) IN CANCER PATIENTS: CLINICAL FEATURES AND SHORT TERM OUTCOMES OF 562 CONSECUTIVE PATIENTS FROM THE EPIPHANY STUDY.
Alberto Carmona-Bayonas, Carme Font, Paula Jiménez Fonseca, Carmen Beato, Laura Faez, Mª Angeles Vicente, Mercedes Biosca,
Olga Madridano Cobo, Juani Plasencia, David Calvo Templado, Angel Dominguez, Pedro Arguis Giménez, Remedios Otero Candelera, Vicente Vicente
C-0446 ROLE OF ARTERIAL CARDIOVASCULAR RISK FACTORS IN THE PATHOGENESIS OF CANCER RELATED VTE.
Francesco Dentali, Mara Mantiero, Jessica Muzzolon, Alessia Pastore, Graziella Pinotti, Walter Ageno
C-0026 THE VALUE OF CT SCANNING FOR THE DETECTION OF OCCULT CANCER IN PATIENTS WITH UNPROVOKED THROMBOEMBOLISM.
Paolo Prandoni, Andrea Piccioli, Enrico Bernardi, Fabio Dalla Valle, Adriana Visonà, carlo Bova, Eugenio Bucheri, Anna Falanga
C-0305 A2MACROGLOBULIN DOES NOT COMPENSATE FOR ANTITHROMBIN DEFICIENCY IN SEVERE LIVER CIRRHOSIS
Romy Kremers, Marie-Claire Kleinegris, Bas de Laat, Rob Wagenvoord, Coen Hemker
C-0320 MICROPARTICLE CHARACTERIZATION IN PATIENTS WITH ACUTE LEUKEMIA AT DIAGNOSIS AND AFTER INDUCTION THERAPY
Benjamin Brenner, Anat Aharon, Inna Tzoran-Rosenthal
C-0374 VENOUS THROMBOEMBOLISM IN HOSPITALISED CANCER PATIENTS DESPITE ELECTRONIC ALERTS AND APPROPRIATE PROPHYLAXIS
WITH LMWH. SHOULD WE CONSIDER HIGHER DOSES IN SOME PATIENTS?
Ramón Lecumberri, Ana Alfonso, Margarita Marqués, Alberto Fernández del Carril, Nicolás Martínez-Calle, Sally Franco,
Alberto García-Mouriz, José A. Páramo
OC3: VASCULAR FUNCTION, AGEING AND PLATELETS (Room 1)
Chairs: Agneta Sieghban, Sweden; Rosario López Pedrera, Spain
C-0427 INCREASED FIBRINOLYTIC SYSTEM IN ELDERLY INDIVIDUALS WITH HEALTHY AGING
Judit Cubedo, Teresa Padró, Francesc Formiga, Assumpta Ferrer, Gloria Padros, Lina Badimon
C-0323 AGE-RELATED CHANGES TO THE MECHANISMS RESPONSIBLE FOR REGULATING PLASMA LEVELS OF VON WILLEBRAND FACTOR AND
FACTOR VIII
Silvia Albanez; Kenichi Ogiwara; Julie Grabell; Paula James; David Lillicrap
C-0230 MONOCYTES THROUGH WNT SIGNALING TRIGGER TISSUE FACTOR EXPRESSION IN MICROVASCULAR ENDOTHELIAL CELLS DURING
TUBE FORMATION
Sonia Espinosa; Gemma Arderiu; Rosa Aledo; Esther Peña; Lina Badimon
C-0522 ASSESSMENT OF VASCULAR FUNCTION IN SIXTY HEALTHY MALES: SOCCERS SHOW IMPAIRED FEMORAL COMPLIANCE. COMPETITIVE
SPORTS AND LOCAL DETRIMENTAL EFFECTS.
Gabriele Cioni; Andrea Berni; Maddalena Pazzi; Rosanna Abbate; Gian Franco Gensini; Maria Boddi
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C-0192 OPTIMAL BINDING OF PLATELET CLEC-2 TO PODOPLANIN UNDER FLOW CONDITIONS REQUIRES PLATELET INTRACELLULAR SIGNALLING
Alice Y Pollitt, Gerard Nash, Steve P Watson, Leyre Navarro Nuñez
C-0520 IMPAIRMENT OF PERIPHERAL VASCULAR FUNCTION IN SYSTEMIC LUPUS ERYTHEMATOUS PATIENTS. DIFFERENCES FROM THE VASCULAR PATTERN OF PATIENTS AT HIGH CARDIOVASCULAR RISK
Gabriele Cioni; Elena Silvestri; Giacomo Emmi; Rossella Marcucci; Mario Milco D’Elios; Maddalena Pazzi; Rosanna Abbate;
Domenico Prisco; Maria Boddi
OC4: ADVANCES IN EXPERIMENTAL MODELS OF ATHEROSCLEROSIS, THROMBOSIS AND VASCULAR BIOLOGY (Room 3)
Chairs: Josune Orbe, Spain; Francesco Violi, Italy
C-0266 REGULATION OF MACROPHAGE POLARIZATION BY EXTRACELLULAR RNA: THE ROLE OF SIALOADHESIN-1
Hector Alejandro Cabrera-Fuentes, Sebastian Galuska, Klaus T. Preissner, William A. Boisvert
C-0018 THROMBUS DEVELOPMENT PROCESSES ARE DEPENDENT ON ENDOTHELIAL INJURIES: EXAMINED BY IN VIVO MOLECULAR FLUORESCENT IMAGING
Satoshi Nishimura
C-0298 ANTITHROMBOTIC AND IN VIVO ANTIPLATELET ACTIVITY OF NEBIVOLOL ARE MEDIATED BY INCREASED PLATELET-DERIVED NITRIC
OXIDE
Stefania Momi, Emanuela Falcinelli, Stefano Evangelista, Paolo Gresele
C-0256 THE EPITHELIAL SODIUM CHANNEL MEDIATES ELEVATED SALT SENSITIVITY OF VASCULAR ENDOTHELIUM IN OLD MICE
Moritz Paar Alexander, Hans Oberleithner, Hermann Pavenstädt, Katrin Kliche
C-0228 PLATELET THROMBOXANE A2 IS AN EXTRACELLULAR MEDIATOR OF THE PROTHROMBOTIC EFFECT OF ERYTHROCYTES
Antonio Moscardó ; Juana Vallés ; Ana Latorre ; Isabel Madrid ; Maria Teresa Santos
C-0342 PLATELET INTERACTION WITH CD34+ PROGENITOR CELLS IN PATIENTS WITH ACUTE CORONARY SYNDROMES. EFFECT OF ANTIPLATELET
TREATMENT
Prokopia Tatsidou, Ntalas Ioannis, Vasileios Chantzichristos, Kallirroi Kalantzi, John Goudevenos, Alexandros Tselepis
OC5: COAGULATION AND FIBRINOLYSIS (Room 6)
Chairs: Pilar Medina, Spain; José Hermida, Spain
C-0459 ACTIVATED FACTOR XI INCREASES THE PROCOAGULANT ACTIVITY OF THE EXTRINSIC PATHWAY BY INACTIVATING TISSUE FACTOR
PATHWAY INHIBITOR
Cristina Puy, Erik I. Tucker, Dave Gailani, András Gruber, Owen J.T McCarty
C-0535 COAGULATION FACTOR XII PROTEASE DOMAIN CRYSTAL STRUCTURE REVEALS A NOVEL ZYMOGEN TRIAD
Jonas Emsley, Pascal Wilman, Monika Pathak
C-0481 ACTIVE PLASMINOGEN ACTIVATOR INHIBITOR-1 (PAI-1) CONCENTRATIONS ARE INCREASED IN PATIENTS WITH A VENOUS THROMBOEMBOLISM (VTE)
Lize Bollen; Miet Peeters; Marc Hoylaerts; Paul Declerck; Peter Verhamme; Ann Gils
C-0288 LACK OF TAFI HAS DELETERIOUS EFFECT ON EXPERIMENTAL ISCHEMIC STROKE: POTENTIAL ROLE OF MICROPARTICLES
Jose A. Paramo Fernández, Carmen Roncal Mancho, Nicoleta Alexandru, Paula Bibiot, JCM Meijers, Jose A Rodriguez,
Adriana Georgercu, Josune Orbe
C-0477 PRIMARY RESPONSE TO INFLIXIMAB THERAPY IN IBD PATIENTS IS REFLECTED IN THE NORMALISATION OF THE HAEMOSTATIC PROFILE
Lize Bollen, Niels Vande Casteele, Miet Peeters, Paul Declerck, Marc Ferrante, Severine Vermeire, Ann Gils
C-0295 THROMBIN AND ACTIVATED PROTEIN C ARE REGULATORS OF NEURODEGENERATION AND INFLAMMATION.
Lyubov Gorbacheva; Shinichi Ishiwata; Georg Reiser; Svetlana Strukova
10:45-11:15 Coffee Break
11:30-13:00 Symposium: INFLAMMATION AND THROMBOSIS (Auditorium 1)
Chairs: Christian Weber Germany; María Borrell, Spain 1. Oxidative Stress and inflammation in thrombosis Francesco Violi, Italy 2. Procoagulant activity of circulating nucleic acids and of neutrophil extracellular traps Klaus T. Preissner, Germany
3. Innate immunity, inflammation and thrombosis. Christian Weber, Germany Symposium: NEW INSIGHTS IN PROTEIN C PATHWAY (Auditorium 2) Chairs: John H. Griffin, USA; Francisco España, Spain
1. Protein C anticoagulant and cytoprotective pathways John H. Griffin, USA 2. Endothelial protein C receptor and thrombomodulin in venous and arterial thrombosis
Francisco España, Spain 3. Endothelial protein C receptor encryption by sPLA2-V: role in thrombosis and cellular protein C resistance
Jose Hermida, Spain
13.15-14.45 Lunch
13.15-14.45 Satellite Symposium: APIXABAN: ADDRESSING THE DILEMMA OF THROMBOSIS VERSUS BLEEDING
ACROSS CLINICAL SETTINGS (Auditorium 2)
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Chair: Gines Escolar, Spain
1. Is there still room for Vitamin K antagonists for stroke prevention in atrial fibrillation and venous thromboembolism treatment
and prophylaxis?
Gines Escolar, Spain
2. Clinical benefits of apixaban for stroke prevention in patients with non-valvular atrial fibrillation
Martin Moser, Germany
3. Consistent benefits of apixaban across clinical settings: the rationale and evidence
Giancarlo Agnelli, Italy 4. The role of haematologist in practice Isabelle Gouin-Thibault, France 5. Concluding summary and Q&A
Gines Escolar, Spain
14.00-14.45 Councillor’s Meeting (Room 8)
14.00-14.45 Satellite Symposium (Auditorium 3)
1. Clinical scores and diagnosis algorithms in haemostasis and thrombosis José A. Páramo, Spain
2. Added value of clinical scores and diagnosis algorithms for improved patients' management - presentation
of a new international tool
José A. Páramo, Spain
3. Clinical cases
Alberto Tosetto, Italy
15.00-16.30 Symposium: TREATMENT OF THROMBOSIS IN CORONARY ARTERY DISEASE IN 2014 (Auditorium 1)
Chairs: Gregory Y.H. Lip, United Kingdom; Gines Escolar, Spain
1. Update in anti-P2Y12 drugs in coronary artery disease Juan José Badimon, USA 2. Update in anticoagulants in coronary artery disease Antonio Fernandez-Ortiz, Spain 3. Global Management of acute coronary syndrome Joao Morais, Portugal JOINT SYMPOSIUM (Auditorium 2)
Sociedad Española de Trombosis y Hemostasia (SETH), Societá Italiana per lo studio dell´Emostasis e della Trombosi (SISET),
Mediterranean League Against Thromboembolic Diseases (MLTD) Chairs: Armando d’Angelo, Italy; Vicente Vicente, Spain 1. Unravelling novel thromboembolic mechanisms. Javier Corral, Spain 2. Blockade of the VWF-GPIb interaction in arterial thrombosis: where are we? Paolo Gresele, Italy 3. What did we learn from RIETE? Manuel Monreal, Spain
4. RNA-based therapeutic approaches to coagulation defects Francesco Bernardi, Italy
16.40-17.20 Poster session Coffee
17.30-19.00 Symposium: ATRIAL FIBRILLATION: NEW ADVANCES IN DIAGNOSIS AND
TREATMENT (Auditorium 1)
Chairs: Juan José Badimon, USA; Francisco Marín, Spain
1. Beyond risk stratification in AF patients Vanessa Roldán, Spain 2. Treatment options in AF: old vs new drugs Peter Svensson, Sweden 3. Translating the results from clinical trials to real life Gregory Y.H. Lip, United Kingdom 20:30
Symposium: GENETICS IN THROMBOSIS (Auditorium 2) Chairs: David A. Lane, United Kingdom; Jordi Fontcuberta, Spain
1. The genomic architecture underlying platelet formation and its relevance to thrombosis
Willem H. Ouwehand, United Kingdom 2. Genome-wide association studies in thrombosis. José Manuel Soria, Spain
3. New approaches to identify genetic risk factors in thrombosis
Frits Rosendaal, The Netherlands
Congress dinner
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NEW SATURDAY SCHEDULE
Saturday 17th
08.30-09.30 SYMPOSIUM THROMBOSIS AND CANCER (Auditorium 1) Chairs: Anna Falanga, Italy; Miguel Sanz Alonso, Spain
1. New and old anticoagulants in cancer Giancarlo Agnelli, Italy 2. Coagulation and cancer: biological and clinical aspects Anna Falanga, Italy 3. Crosstalk platelets-inflammation in angiogenesis Harald F. Langer, Germany
09.40-10.40 ORAL COMUNICATIONS (OC1, OC2, OC3, OC4, OC5)
OC1: TRIGGERS OF VASCULAR DYSFUNCTION AND THROMBOSIS (Auditorium 2)
Chairs: María Borrell, Spain; Pablo García de Frutos, Spain
C-0033 PM10-INDUCED MICROPARTICLE GENERATION BY HUMAN MONOCYTIC CELLS: A NOVEL LINK BETWEEN CARDIOVASCULAR DISEASES
AND AIRBORNE POLLUTANTS.
Tommaso Neri, Eleonora Longhin, Silvia Petrini, Maurizio Gualtieri, Stefania Lombardi, Yuri Carmazzi, Cristina Balia, Valentina Scalise, Marina Camantini,
Roberto Pedrinelli, Pierluigi Paggiaro, Alessandro Celi
C-0392 HYPOXIA INDUCED VON WILLEBRAND FACTOR UPREGULATION IS MEDIATED THROUGH TOLL LIKE RECEPTOR 2- MYD88-STIMULATORY
PROTEIN 1 DEPENDENT PATHWAY
Bandana Singh, Indranil Biswas, Manish Sharma, Gausal Khan
C-0089 UNEXPECTEDLY HIGH RATE OF PULMONARY ARTERIES RECANALIZATION IN PATIENTS WITH PULMONARY EMBOLISM TREATED WITH
ANTICOAGULANTS ALONE
Paolo Prandoni, Raffaele Pesavento, Lucia Filippi, Valentina Vedovetto, Giorgio De Conti, Annachiara Frigo, Antonio Pagnan
C-0507 HEPTEST-STAT COAGULATION ASSAY DETERMINES SPECIFICALLY RIVAROXABAN, APIXABAN AND DABIGATRAN FROM PLASMA SAMPLES ON TREATMENT
Job Harenberg; Christina Giese; Shanshan Du; Christel Weiss
C-0594 ADHERENCE OF STAPHYLOCOCCUS AUREUS TO ENDOTHELIUM UNDER SHEAR STRESS IS MEDIATED BY VON WILLEBRAND FACTOR-BINDING PROTEIN
Peter Verhamme; Jorien Claes; Thomas Vanassche; Marijke Peetermans; Laurens Liesenborghs; Karen Vanhoorelbeke; Ruth Heying; Marc Hoylaerts
C-0163 IMMUNOGLOBULIN FROM MULTIPLE MYELOMA INTERFERES THE THROMBIN-ANTITHROMBIN AXIS CAUSING A SEVERE COAGULOPATHY BY ACTIVATION OF ANTITHROMBIN.
Irene Martínez-Martínez, José Ramón González-Porras, María José Cebeira, Fernando J Corrales, Javier Corral, Vicente Vicente,
Felipe de Arriba
OC2 OLD AND NEW OAS (Auditorium 2)
Chairs: Manuel Monreal, Spain; Jordi Fontcuberta, Spain
C-0589 RELATIONSHIP OF THE SAME-TT2R2 SCORE TO POOR QUALITY ANTICOAGULATION, STROKE, CLINICALLY RELEVANT BLEEDING AND
MORTALITY IN PATIENTS WITH ATRIAL FIBRILLATION
Gregory Y. H. Lip, Ken Haguenoer, Christophe Saint-Etienne, Laurent Fauchier
C-0504 A RANDOMIZED TRIAL OF GENOTYPE-GUIDED DOSING OF ACENOCOUMAROL IN SPANISH POPULATION
Juan Jose Cerezo Manchado, Mario Rosafalco, Ana Isabel Antón, Jose Padilla, Ana Belen Martinez, Javier Corral, Vicente Vicente,
R Gonzalez-Conejero, Vanessa Roldan
C-0303 PROSPECTIVE CONTROLLED STUDY TO IDENTIFY THE PREFERENCE OF PATIENTS FOR A CONVENTIONAL OR DIRECT ORAL ANTICOAGULANT USING A SHORT QUESTIONNAIRE
Shabnam Zolfaghari, Job Harenberg, Lutz Frölich, Philipp Wild, Jürgen Prochaska, Jan Beyer-Westendorf, Jürgen Koscienly,
Christel Weiss
C-0202 DECREASED LEVELS OF PROCOAGULANT PHOSPHOLIPIDS IN BLEEDING PATIENTS WITH OVERCOAGULATION BY VITAMIN K ANTAGONISTS
Patrick Van Dreden, Emmanuel Mathieu, Matthieu Grusse, Dominique François, Marc Vasse
C-0487 NT-PROBNP PROVIDED COMPLEMENTARY PROGNOSTIC INFORMATION TO AN ESTABLISHED CLINICAL RISK SCORE (CHA2DS2-VASC)
FOR THE PREDICTION OF STROKE/SYSTEMIC EMBOLISM.
Vanessa Roldan, Juan Antonio Vilchez, Sergio Manzano-Fernández, Eva Jover, Pilar Gallego, Carmen M Puche, Mariano Valdes,
Vicente Vicente, Gregory Y Lip, Francisco Marin
C-0375PREVENTIVE AND ACUTE TREATMENT OF PROSTHETIC CARDIAC VALVE THROMBOSIS: AN UNRESOLVED PROBLEM
Gonzalo Artaza, Veronica Pons, Laura Lopez Andreoni,Georgina Stefania Daher, Carlos Palacio1, Isabel Montserrat, Inmaculada Nicolau, Ana Marin,
Francesc Bosch, Amparo Santamaría
OC3 GENETICS OF THROMBOSIS AND HAEMOSTASIS (Auditorium 3)
Chairs: José Manuel Soria, Spain; Silvia Navarro Rosales, Spain
C-0260 IDENTIFICATION OF RXRA/VDR ELEMENTS INVOLVED IN THE REGULATION OF ANTITHROMBIN LEVELS. RELEVANCE IN ANTITHROMBIN
DEFICIENCY.
María Eugenia de la Morena-Barrio, Mara Toderici, Antonia Miñano, Jose Padilla, Ana Isabel Antón, Nuria García-Barberá,
Thomas Binder, Juan Carlos Souto, Vicente Vicente, Javier Corral
C-0384 HIGH PREVALENCE OF ANTITHROMBIN BUDAPEST 3 MUTATION IN HUNGARY, INVESTIGATION OF FOUNDER EFFECT
Reka Gindele, Marianna Speker, Ágnes Udvari, Zsolt Oláh, György Pfliegler, Ágota Schlammadinger, Katalin Rázsó, Erzsébet Marján,
Hajna Losonczy, Anna Selmeczi, Zoltán Boda, László Muszbek, Zsuzsanna Bereczky
C-0380 CLINICAL AND BIOCHEMICAL CONSEQUENCES OF MET1ILEU MUTATION IN SERPINC1 GENE: GENERATION OF A SMALL NON-INHIBITORY
ANTITHROMBIN VARIANT WITHOUT THE N-TERMINAL REGION BY USE OF AN ALTERNATIVE INITIATION CODON THAT HAS A STRONG
GAIN-OF-FUNCTION ASSOCIATED WI
José Navarro-Fernández, Ingunn Dybedal, Sonia Águila, Natalia Bohdam, Fernando Corrales, Carmen Miqueo, Marianne Andresen, Francisca Ferrer, Geir
E. Tjønnfjord, Irene Martínez-Martínez, Ketil Heimdal, Vicente Vicente, Javier Corral, Ulrich Abildgaard
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C-0337 MOLECULAR CHARACTERIZATION OF NOVEL PROTEIN C MUTATIONS (P.ASP77GLY, P.ALA163VAL AND P.ALA163GLU) CAUSING PROTEIN C
DEFICIENCY
Kitti Bernadett Kovíçcs, István Pataki, Helga Bíçrdos, György Pfliegler, Istvíçn Komíçromi, Attila Fekete, Gizella Haramura, Ríza ídíçny, Gyírgy Balla, László
Muszbek, Zsuzsanna Bereczky
C-0047 CYTOPROTECTIVE SELECTIVE HUMAN 3K3A-ACTIVATED PROTEIN C VARIANT DETOXIFIES HISTONE H1 AND STABILIZES ENDOTHELIUM
FROM PRO-INFLAMMATORY CYTOKINES.
Jose Fernandez, Ranjeet Sinja, Laurent Mosnier, Xiao Xu, Thomas Cramer, John Griffin
C-0198 GENOTYPES OF VKORC-1 AND SENSITIVITY TO ORAL ANTICOAGULANTS IN PEDIATRIC POPULATION
María P Vera Morandini, Lucia Remotti, Silvia H Grosso, María F Alberto, Analia Sánchez-Luceros, Susana S. Meschengieser,
María A Lazzari, Alicia N Blanco
OC4: MICRORNAS IN THROMBOSIS AND HAEMOSTASIS (Room 1)
Chairs: Teresa Padró, Spain; Constantino Martínez Gómez, Spain
C-0232 MICROVESICLE-ASSOCIATED MICRORNA-19A AS A POTENTIAL MODULATOR OF BLOOD-CELL DERIVED TISSUE FACTOR IN FAMILIAL
HYPERCHOLESTEROLEMIA
Rosa Suades, Teresa Padró, Rodrigo Alonso, Pedro Mata, Lina Badimon
C-0547 TISSUE FACTOR PATHWAY INHIBITOR EXPRESSION IS REGULATED BY MIR-27A-3P IN ENDOTHELIAL CELLS.
Ana Belen Arroyo, Salam Salloum-Asfar, Carlos Perez-Sanchez, Nuria Garcia-Barbera, Gines Luengo-Gil, Chary Lopez-Pedrera,
Vicente Vicente, Rocio Gonzalez-Conejero, Constantino Martinez
C-0420 MICRORNA EXPRESSION PROFILE IN EPICARDIAL FAT IN SUDDEN CARDIAC DEATH FROM CORONARY ARTERY DISEASE
Aitana Braza-Boils, Josep Marí-Alexandre, Pilar Molina, Diana Domingo, Jorge Sanz, Jennifer Sancho, Yolanda Abellán,
Natividad Castillo, Miguel Ángel Arnau, Juan Giner, Anastasio Montero, Amparo Estellés, Esther Zorio
C-0423 MICRORNAS IN SUDDEN CARDIAC DEATH FROM CORONARY ARTERY DISEASE. ITS RELATIONSHIP WITH DYSLIPIDEMIA AND NON-ALCOHOLIC FATTY LIVER DISEASE.
Josep Marí-Alexandre, Aitana Braza-Boils, Pilar Molina, Diana Domingo, Yolanda Abellán, Jennifer Sancho, Paloma Hevia,
Miguel Ángel Arnau, Javier Gómez, Juan Giner, Antonio Salvador, Amparo Estellés, Esther Zorio
C-0418 MIRNAS 16, 424 AND 29C REGULATE VEGF-A EXPRESSION IN ENDOMETRIAL STROMAL CELLS FROM WOMEN WITH ENDOMETRIOSIS
Aitana Braza-Boils, Salam Salloum-Asfar, Josep Marí-Alexandre, Ana Belén Arroyo, Rocío González-Conejero, Vicente Vicente, Amparo Estellés, Juan
Gilabert-Estellés, Constantino Martínez
C-0171 IDENTIFICATION OF A MICRORNA PROFILE RELATED TO HYPERTROPHIC CARDIOMYOPATHY
Emma Plana, Diana Domingo, Laura Martos, Elena Fernández, Jennifer Sancho, Yolanda Abellan, Mª del Carmen Salvador, Esther Zorio, Miguel Ángel
Arnau, Anastasio Montero, Francisco España, Pilar Medina
OC5: PLATELET PHYSIOLOGY (Room 6)
Chairs: Jose Antonio Páramo, Spain; Jose Rivera, Spain
C-0189 BLOCKADE OF GRP78 MOBILIZATION PREVENTS THE ACTIVATION OF HUMAN PLATELETS
Raquel De la Torre, Esther Peña, Gemma Vilahur, Lina Badimon
C-0196 PLATELET BIOGENESIS FROM BONE MARROW MEGAKARYOCYTES IS DYNAMICALLY REGULATED IN TWO MORPHOLOGICALLY DISTINCT
MODES BY CYTOKINE BALANCES
Satoshi Nishimura
C-0462 CAR EXPRESSION ON PLATELETS SURFACE IS RELATED TO INFLAMMATION.
Elena Gupalo, Liudmila Buryachkovskaya, Irina Uchitel, Petr Chumachenko, Natalia Mironova
C-0215 SIRTUINS: NEW REGULATORS OF PLATELET FUNCTION
Antonio Moscardó, Maria Teresa Santos, Ana Latorre, Juana Vallés
C-0485 ROLE OF CYCLIN-DEPENDENT KINASE 6 (CDK6) IN PLATELET FUNCTION AND HAEMOSTASIS IN MICE
Begoña Hurtado, Lola Bellido-Martín, Ginés Escolar, Pablo García de Frutos
C-0604 MYOSIN LIGHT POLYPEPTIDE 6 IS REDUCED IN PLATELETS FROM DEEP VEIN THROMBOSIS PATIENTS.
Mariane Flores Nascimento, Regiane Ferreira, Carolina Lanaro, Joyce Annichino-Bizzacchi
10.45-11.15 Coffee Break
11.30-13.00 STATE OF ART SESSION AND PRESIDENTIAL FAREWELL SYMPOSIUM: NEW CHALLENGES IN THROMBOSIS AND CARDIOVASCULAR DISEASE (Auditorium 1)
Chairs: Lina Badimon, Spain; Muzaffer Demir, Istambul
Proteomics in thrombosis: Current perspective Albert Sickmann, Germany Air Pollution thrombosis and cardiovascular disease Pier Manucci, Italy
Implications of thrombosis in solid versus hematological tumors Gabriela Cesarman, Mexico
13.15-14.45 Satellite Symposium: PARADIGM SHIFT IN VTE-TREATMENT (Auditorium 2)
Chair: Giancarlo Agnelli, Italy
1. Welcome and introduction
Giancarlo Agnelli, Italy
2. DVT and PE: a single disease?
David Jiménez Castro, Spain
3. PREvention oF thromboembolic events - European Registry in Venous ThromboEmbolism (PREFER in VTE)
Giancarlo Agnelli, Italy
4.Efficacy and safety of edoxaban in a broad spectrum of VTE patients (Hokusai)
Peter Verhamme, Belgium
5. Panel discussion
6. Closing remarks
Giancarlo Agnelli, Italy
13.15-14.45 Lunch
15.00-16.30 MLTD General Assembly (Auditorium 3)
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