College of Graduate Studies Annual Report 2011-2012

Transcription

College of Graduate
Studies
Annual Report 2011-2012
COLLEGE OF GRADUATE STUDIES
ANNUAL REPORT
July 1, 2011 – June 30, 2012
TABLE OF CONTENTS
Dean’s Executive Summary
1
College Budget
6
Training Grants
7
NRSA Awards
10
Organizational Structure Of The College
14
Graduate Council Membership
15
College Committees
Admissions Committee
16
Credentials Committee
21
Curriculum Committee
22
Distinguished Graduate Of The Year Committee
25
First Year Curriculum Steering Committee
26
First Year Progress Committee
28
Office of Postdoctoral Affairs
29
Student Research Day
31
Graduate Student Association
33
Multicultural Graduate Student Association
35
Master Of Science In Clinical Research
45
Medical Scientist Training Program
54
Dental Medicine Scientist Training Program
99
Molecular & Cellular Biology & Pathobiology Program
105
Summer Health Professionals Research Program
121
Summer Undergraduate Research Program
128
Governor’s School for Science & Math
133
Department Programs
Department Of Biochemistry and Molecular Biology
135
Department Of Bioengineering
141
Department Of Biostatistics And Epidemiology
147
Department Of Cell And Molecular Pharmacology And
Experimental Therapeutics
158
Department Of Drug Discovery and Biomedical Sciences
161
Department Of Microbiology And Immunology
168
Department Of Neurosciences
173
Nursing Doctoral Program
188
Department Of Pathology & Laboratory Medicine
199
Post Graduation Positions Of Our Graduates
204
Dissertation Titles Of Graduates
207
First Year Students
212
College Of Graduate Studies Faculty
218
Executive Summary
Dear faculty, pre-doctoral and postdoctoral trainees and MS degree students;
As I write this executive summary, I would like to take a moment to reflect on the
enormous accomplishments and metamorphosis that the college has undergone since
July 2000. The accomplishments can be measured in several ways. The number of
applicants to our PhD program has doubled over that time frame and the number of
applicants to our MSTP has increased 4 fold. The quality of our trainees has increased
significantly. They are very competitive for NIH NRSA fellowships, with a success rate
at least twice that of the national average. We have many T32 training grants that did
not exist in 2000 and those that have undergone a competing renewal scored
extraordinarily well. We have been able to offer a first year core curriculum that
embraces the most important aspects of the biomedical sciences and prepares our
trainees on a path to be independent scientists and achieve their career goals.
We have been able to reward outstanding teachers in our first year core curriculum with
the “Outstanding Teacher of the Year Award”. We also recognize our distinguished
graduate each year with the “Distinguished Graduate of the Year Award”.
In the early days of the transformation of the college three individuals played key
leadership roles. They were Ed Krug, George Lindenmayer and Adam Smolka. As you
know Ed and Adam continue to play key leadership roles in the college’s programs.
George retired and moved to Seattle where he is working part time. Joann Sullivan has
played a key role in the college’s extraordinary success rate in obtaining T32 and other
extramural competitive training grants. Cynthia Wright has been the PI on several of the
college’s training grants and in particular has been very effective in enhancing the
diversity activities of the college and starting a new certificate program for the college.
Of particular note is her success in improving the retention rate for underrepresented
minorities.
The college has two new endowments; one to support the annual campus wide
research day and the other to support college enrichment activities; one in particular, a
Dean’s seminar series. There is also a fund established to provide the financial reward
for the outstanding teacher of the year.
These are just a few of the many positive changes that have taken place in the college
over the past 12 years. I hope that you will share with me the pride of accomplishment
that has taken place over this period of time. For in the final analysis, it is our faculty
and trainees that enrich the college and enhance its ever-growing positive reputation.
•
•
In September, the College moved into a new suite of offices in the Bioengineering
Building. This is an outstanding suite that not only provides offices for Assistant and
Associate Deans but also offices for all the staff. There is also a conference room
that has video conferencing and is available for use by anyone who is associated
with the College. The move to a respectable suite of offices was long overdue. We
thank Dr. John Raymond, former Provost and Vice-President for Academic Affairs
for arranging for the College to move to the new space.
A committee was charged by the Dean to determine the cost of educating a
graduate student. The committee has delivered its report to the Dean who in turn
has delivered it to the Provost. The Provost discussed it with the Graduate Council
on August 8, 2012.
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Reestablished the Dean’s seminar series, which provides $2,000 annually for each
graduate program to invite a speaker who will spend most of the day interacting with
predoctoral and postdoctoral trainees.
The Graduate Council established a new policy concerning MS degree seeking
students. All MS students will register full time, which is 9 hours. This was instituted
in part because of the new budget model.
A new certificate program in the biomedical sciences was established by Dr. Cynthia
Wright and Dr. Laura Kasman. This certificate program, which is targeted to
applicants to the medical school that did not get accepted, is very well thought out
and will provide the students with an excellent set of experiences that will prepare
them well for their re-application to medical school. In addition, it will be a significant
source of revenue for the College. This year, 8 students were admitted. The plan is
to admit 20 students in the next and coming years.
A memorandum of understanding was signed with Ningbo University to develop an
exchange program for trainees and faculty in the neuroscience program. In addition,
two of their faculty will take the MSCR course with a plan toward eventually using
that training to establish collaborative clinical trials in addiction between MUSC and
Ningbo. Dr. Peter Kalivas was instrumental in facilitating the MOU.
This has been another challenging year for the College. In spite of major budgetary
cuts, significantly greater than last year, we were able to accomplish much and believe
that we have a very strong incoming class of PhD and MD/PhD students.
The College by all measures continues on an upward trajectory. However, we continue
to face serious challenges to our mission. The reduction in our budget over the last 4
years has significantly curtailed some of the programs and activities that the College
has funded. The new budget system to be implemented in 2012 will provide additional
challenges to the College. The need for teachers for our didactic offerings continues to
be an ongoing challenge for our College.
Accomplishments Of The Faculty, Students, Fellows And Staff
•
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•
•
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Dr. Cynthia Wright continues to be very active, in particular devoting a significant
amount of time to recruitment activities and outreach programs. She also submitted
two training grants for competing renewal and both grants were site visited.
Dr. Ed Krug, Assistant Dean for Postdoctoral Affairs, has continued to be very
active, both locally and nationally. He was elected chair–elect of the AAMC GREAT
Group Postdoctoral Leadership section. He also facilitated MUSC being selected for
the National Postdoctoral Association Annual Conference in March 2013.
Dr. Joann Sullivan, Assistant Dean for Extramural Program Development, continues
to be extraordinarily helpful, providing significant assistance and guidance for the
submission of major training grants.
Dr. Thomas Hulsey, Assistant Dean for Global Education Programs, continues to
develop our MSCR degree program for global distribution. There are 3 physicians
from the Drum Tower Hospital, Nanjing, China currently participating.
Ms. Eileen McFadden was hired as administrative coordinator to work in the Office
of Postdoctoral Affairs and work with Dr. Ed Krug.
The eleventh annual “Outstanding Teacher Of The Year “ award was won by Dr.
Yiannis Koutalos. The ten nominees for the outstanding teacher were; Carl Atkinson,
Craig Beeson, Scott Eblen, Robert Gemmill, Debra Hazen-Martin, YeTi Hsu, Yiannis
Koutalos, Rick Schnellmann and Julie Woolworth.
The Multicultural Graduate Student Association was again awarded the MUSC
Gives Back Award.
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•
•
Our graduate students continued their very successful community outreach program
titled “Graduate Students Reaching Out With Science” (GROWS). Seventeen
students have visited seven middle and high schools and have been very
enthusiastically received. Collectively, they have spent 182 hours of volunteer
teaching in these outreach education activities.
During the past year, the College was home to 201 postdoctoral fellows, 130 PhD,
61 MSTP, 6 DMD/PhD, 2 PharmD/PhD, 53 CON/PhD, 18 MS, 17 MSCR and 107
global MSCR students.
The College graduated 21 PhD, 9 MD/PhD, 8 Nursing PhD, 4 MS and 18 MSCR
students.
Our students have an impressive list of accomplishments as demonstrated by the
numerous national honors, awards, and individual fellowships that they have
received and their publications. These are well documented in the individual
department and program reports.
Recruitment and Admissions
•
•
•
•
•
Distributed a recruitment letter for the College’s programs to approximately 3,000
undergraduate students taking the GRE, 200 McNair scholars and students
attending science and recruitment fairs.
Distributed a recruitment letter for the MSTP to approximately 2,000 undergraduate
students scoring 32 or better on the MCAT.
The College received 222 applications (a new all time high) for the PhD program, 77
applicants were interviewed, 54 offers were made and 24 will matriculate. The GRE
average percentile score of the incoming students is 71.8 for verbal and 68 for
quantitative and the average GPA is 3.47.
The College received 176 applications (largest number yet) for the MSTP. The
average GPA for those interviewed was 3.75 and MCAT was 33.8. Fifty-two
applicants were interviewed. We made 20 offers of acceptance and we had 4
matriculants. The average GPA of the matriculants is 3.76 and the average MCAT is
34.3.
Matriculated 24 PhD, 4 MS, 25 MSCR and 17 Nursing PhD students.
Training Grants and Fellowships
New training grant submissions- funded
•
Summer Undergraduate Research Program in Substance Use Disorders. PI,
Antonieta Lavin
New training grant submissions- not funded
•
Molecular and Cellular Basis of Inflammation and Immunity. PI, Steve Tomlinson
Training Grants Submitted for Competing Renewal
•
•
MUSC Minority Student Development Program. PI, Cynthia Wright
MUSC-Claflin Cooperative for Postdoctoral Academic Career Development. PI,
Cynthia Wright
Current Training Grants
•
Eleven T32 training grants, one R25 pre-doctoral extramural training grant, and two
DOE GAANN grants supported 63 pre-doctoral PhD positions.
3
•
•
One T35 and two R25 training grants support 54 short-term summer training
positions.
Fifteen extramural postdoctoral training grants (T32) support 47 postdoctoral
positions.
Individual Fellowships and Scholarships
•
•
The national success rate for students applying for a Ruth L. Kirschstein NIH
Research Service Award (F30, F31) is about 30%, while for our students, it is
approximately 75%, an extraordinary accomplishment. This last year there were 23
students who were funded by either an F30 or F31 fellowship, 4 were funded by
American Heart Association fellowships and 2 were funded by the Department of
Defense.
We also have 7 postdoctoral fellows supported by individual F32 training grants.
Additional Accomplishments
•
•
•
•
•
•
•
•
•
Successfully completed the first year core curriculum for the eleventh year.
Held the tenth annual “Parent’s Luncheon and Awards Ceremony” for our graduates.
Awarded the twelfth and thirteenth “Distinguished Graduate of the Year Award” –
Russell Jenkins, MD, PhD, Mentor, Yusuf Hannun, MD
Khaled Moussawi, MD, PhD, Mentor, Peter Kalivas, PhD
The summer undergraduate research program (SURP) hosted 65 students. Thirtythree were underrepresented minorities and there were a total of 381applications for
the positions. To date the College’s faculty have trained a total of 1107 SURP
students. Approximately 213 of these students have enrolled in one of MUSC’s 6
Colleges.
The Summer Health Professions program hosted 46 students. Seventeen students
were underrepresented minorities.
The Summer Research Program for the Governor’s School for Science and
Mathematics hosted 12 students.
The College hosted 12 Porter-Gaud female students for a semester didactic and
laboratory biomedical sciences experience.
Established a formal high school research program for rising seniors (Summer) and
seniors (Fall/Spring) who want more experiences in the STEM disciplines.
Co-organized the E.E. Just Symposium with 369 undergraduates and 23 faculty
advisors were registered.
We have set a series of goals for the College for the coming year, many of which are
commensurate with the strategic plan and some of which have arisen to meet some
immediate needs.
Goals for 2010-2011
•
•
Hire a new Dean for the College.
Raise the PhD stipends by $1,000 and develop a graduated stipend increase
program for students once they have entered into candidacy.
Recruitment
•
•
•
Continue to distribute the recruitment letters for the PhD and MD/PhD programs to
students taking the GRE or MCAT, respectively.
Continue to develop additional recruitment tools and strategies.
Increase number of applicants for the PhD programs by 5%.
4
•
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•
•
Increase quality of applicants and matriculants as measured by GRE scores, GPA
and undergraduate research experience. Develop a more competitive recruitment
package for applicants.
Increase the diversity of the student body of the College.
Develop liaisons with undergraduate institutions that have a large number of
underrepresented minorities that matriculate into PhD programs or MSTP’s in the
biological sciences.
Establish one new recruitment scholarship for PhD students.
Other
•
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•
Submit at least one new pre-doctoral training grant.
Continue to work with the Development Office to:
1.
Raise money for scholarships.
2.
Endow the Dean’s Chair.
3.
Increase the size of the endowment for the Perry V. Halushka Student
Research Day.
Work with the Provost to implement the new budget system to the advantage of the
College.
5
College Budget
Major Expense Categories
Personnel
$729,950
Stipends – PhD, MSTP
$706,588
Health Insurance
$57,047
Travel (Student, recruitment, seminar speakers, faculty, consultants)
$92,148
Entertainment/Student Life (includes recruitment, seminars)
$59,555
Summer research (stipends/supplies/housing/travel)
$61,056
Dean’s student fellowship incentive awards
$22,500
Student Research Day Awards
$14,300
Equipment (computer, monitor, conference room table)
$6,695
Postdoctoral (ISOP, ethics retreats, workshops, Postdoc Association)
$6,353
6
TRAINING GRANTS ADMINISTERED BY THE COLLEGE’S OFFICE AND STAFF
AND/OR SUPPORTING SUMMER RESEARCH PROGRAMS
Title/Source/PI
Summer Health Professional Training
Grants
Short Term Training in Health Professional
Schools
NIH/NIDDK 5 T35 DK07431-28
PI - Dr. Leonard Egede
--funds 24 summer stipends for
medical/dental/pharmacy students for 8-12
weeks
Summer Research Program for Minority
Medical Students
NIH/NHLBI 1 R25 HL096316-03
PI - Dr. Donald Menick
--funds 10 summer stipends for 10-12 weeks
Post-Transcriptional Regulation of
Periodontal Diseases
NIH/NIDCR 2 T32 DE017551-06
PI - Dr. Keith Kirkwood
--funds 6 summer stipends+ other costs for
dental students for 8-12 weeks
Summer Undergraduate Research
Program Training Grants
MUSC Short Term Research Education
Program to Increase Diversity
NIH/NHLBI 5R25 HL092611-05
PI - Dr. Cynthia Wright
--funds 16 undergraduate summer salaries
for 10 weeks
Palmetto Academy 2012: Site at MUSC
College of Charleston
PI - Dr. William Scott Argraves
--funds 3 undergraduate summer stipends +
other costs for 10 weeks
SC Collaborative Undergraduate HBCU
Student Summer Training Program
DOD - W81XWH-12-1-0043
PI – Dr. Marvella Ford
7
Budget Period
Total $
5/1/12-4/30/13
Year 28 of 30
$182,943
4/1/12 – 3/31/13
Year 3 of 4
$107,398
7/1/11-6/30/16
Year 6 of 10
$530,113
5/1/12-4/30/13
Year 5 of 5
$110,592
5/1/11-4/30/12
Year 3 of 3
$30,000
3/1/12-2/28/13
Year 1 of 1
$64,810
Southeastern Virtual Institute for Health
Equity and Wellness (SEVIEW)
DOD, Dept of the Army
USAMRAA W81XWH-10-2-0057
PI Dr. Marvella Ford
SC Cancer Disparities Research Center
PI – Dr. Marvella Ford
other costs
South Carolina Clinical and Translational
Research Institute (SCTR)
Institutional Funds
PI - Dr. Kathleen Brady/Co-PI – Dr. Perry
Halushka
Neurobiology of Addiction Research Center
Pilot Core C NIH/NIDA 5 P50 DA015369-10
PI – Dr. Jacqueline McGinty
-funds 4 or more undergraduate summer
salaries + other costs for 10 weeks
in Substance Use Disorders
1R25DA033680-01
PI – Antonieta Lavin
-funds multiple undergraduate salaries
+ other costs for ten weeks
PhD Training Grants
Graduate Education at the Interface of
Human Biology and New Technologies
US Department of Education
PI - Dr. Perry Halushka
--funds 5-7 PhD stipends
MUSC MBRS IMSD Program
NIH/NIGMS 5R25 GM072643-08
PI – Dr. Cynthia Wright
--funds 5 PhD students and includes faculty
salaries for teaching support
8
7/1/10-6/30/13
Year 1 of 1
$885,068
9/26/11-8/31/12
$188,782
4/1/12-3/31/13
$26,000
5/1/12-4/30/13
$116,656
7/1/12-6/30/13
$96,374
8/15/11-8/14/12
Year 3 of 3
$219,875
5/1/12 – 4/30/13
Year 8 of 8
$319,797
MD/PhD Training Grant
Medical Scientist Training Program
NIH/NIGMS 2 T32 GM008716-13
PI - Dr. Perry V. Halushka
--funds 8 MSTP stipends
7/1/12-6/30/13
Year 14 of 15
$321,232
Postdoctoral Related Grants
MUSC-Claflin Cooperative for Postdoctoral
Academic Career Development
NIH/NIGMS 5 K12 GM081265-05
PI - Dr. Cynthia Wright/Co-PI – Dr. Ed Krug
--funds 3 postdoc scholars and program
related costs
Miscellaneous Grants
2012 Ernest E. Just Symposium
SC Research Authority Task Order 0065
PI - Dr. Titus Reaves
9
8/1/11-7/31/12
Year 5 of 5
$377,537
1/1/12-4/30/12
$10,000
Students with NRSA or NSF Awards
Emily Allen
NSF
9/1/11-8/31/16, $30,000 per year
A Comparative Analysis of Oxidative Stress-Response in PSW iPSCs and Mouse ESCs
Deanna Baker
5F31AR057307-03
7/1/11-6/30/12, $36,289 per year
The Role of Sphingosine Kinase 1 in a Mouse Model of Chronic Inflammation
Tiffany Baker
5F30DC010522-03
9/28/09-9/27/15, $35,099 per year
Heat Shock Protein-Induced Protection Against Cisplatin-Induced Hair Cell Death
Jacob Beckley
1F31DA030891-02
7/1/12-6/30/14, $42,232 per year
Neuroplasticity Associated with Acute Toluene Inhalation
Jennifer Blakely (New)
1F30DK091107-01
9/1/11-8/31/14, $36,703 per year
Stimulation of Mitochondrial Biogenesis with 5-HT Receptor Agonists
Sarah Brice (New)
1F30DK092125-01A1
9/1/11-8/31/14, $36,703 per year
Metabolic Determinants of Cardiac Bioactive Sphingolipids in Lipid Overload
Amanda Buff (New)
5F30DE021612-01A1
7/1/11-6/30/14, $42,045 per year
pGlcNAc Stimulates Wound Healing and Defensin Expression via AKT1
Michael DeFee
5F30DE020203-03
12/1/10-11/30/13, $48,032 per year
The Role of Cell Surface Heat Shock Protein 90 in KSHV Pathogenesis
Christopher Gault (Final Year)
5F30HL093991-03
2/1/09-1/31/12, $39,007 per year
The Role of Sphingosine Kinase 1 in Ras-Initiated Lung Carcinogenesis
10
Linda Heffernan-Stroud
5F30ES017379-03 (Final Year)
12/1/09-11/30/12, $39,877 per year
Role of Sphingosine Kinase 1 in the p53-dependent DNA Damage Response
Keely Morris
5F30DK089696-03
6/1/10-5/31/14, $40,855 per year
The Role of Complement un Hepatic Ischemia Reperfusion Injury and Regeneration
Thomas Mullen
5F30ES016975-04
7/15/08-7/14/12, $37,010 per year
Ceramide Synthases CERS5 and CERS6 Regulate Pathways of Programmed Cell
Death
Natasha New (New)
1F31AA020445-01A1
9/15/11-9/14/14, $36,703 per year
Adolescent Alcohol, Epigenetics, and Alterations in the Adult Prefrontal Cortex
Joseph Palatinus
5F30HL095320-04
2/1/09-1/31/14, $36,637 per year
Connexin 43 Gap Function Dynamics in the Diabetic Heart
Anthony Parker (New)
1F31DE022246-01
8/1/11-7/31/12, $42,600 per year
Estimation of Periodontal Disease Progression in the Presence of Diagnostic Error
Aram Parsegian
1F31DA029431-02
1/1/12-12/31/12, $41,242 per year
Impact of Meth Self-Administration on Glutamate and Dopamine in the
Corticoaccumbens Pathway
Sahar Saddoughi
5F30ES019464-02
8/1/10-7/31/15, $39,445 per year
Suppression of Lung Cancer Growth by Ceramide
11
Justin Schwartz (New)
1F32DK092070-01A1
9/1/11-8/30/12 -01 $67,212 per year
Mechanism-Based Discovery of Protectants against Iron-Dependant Oxidative Injury
R. David Sentelle
5F30DE021295-01
9/1/11-8/31/15, $47,600 per year
Role of Ceramide in Inducing Lethal Autophagy in Head and Neck Cancer
Natalie Straight (New)
1F31AA021618-01, $52,892 per year
4/1/12-3/31/15
Homer2 and Ethanol-Associated Neuroadaptations
Kyle Strickland
5F30DK083215-03
5/5/10-5/4/13, $46,800 per year
Regulation of DNA Methylation by a Major Folate Enzyme
Joseph Taylor (New)
1F30DA033748-01
3/22/12-3/21/15, $36,532 per year
Role of the Supraspinal Opioidergic Circuit in Prefrontal Transcranial Magnetic
Stimulation-Induced Analgesia
Ryan Whitaker (New)
1 F30 DK096964-01
7/1/12-6/30/16, $52,892 per year
Stimulation of Mitochondrial Biogenesis with PDE3 Inhibitors
Parker Wilson (New)
1F30DK083208-01A2
8/15/11-8/14/14, $42,605 per year
Mechanisms of Diabetic Renal Damage: Role of the Kinin Receptors
Xiaoyi Zhang (New)
1F30CA165518-01A1
7/1/12-6/30/13, $43,972 per year
The Role of Mitogen-Activated Protein Kinase Phosphatase-1 in Tumor Progression
12
Students with Department of Defense or American Heart Association Awards
Obaidullah Aseem
American Heart Assoc.
7/1/10-6/30/12, $23,000 per year
The Role of Cubilin in High Density Liporotein Homeostasis
Thomas Beckham
DoD - W81XWH-11-1-0334
4/11/11-11/10/13, $38,136 per year
Evaluation of Acid Ceramidase Over Expression Induced Activation of the Oncogenic
Akt Pathway in Prostate Cancer
Laura Briggs
7/1/11-6/30/13, $23,000 per year
The Role of BMP4 In the Development of the Dorsal Mesenchymal Protrusion
George Daniel Grass (Final Year)
DoD - W91ZSQ9277N682
2/1/10-2/28/13, $42,040 per year
Functional Interactions of Hyaluronan, CD44, and Emmprin in Breast Cancer
Progression
Erin Pardue
7/1/10-6/30/12, $23,000 per year
The Influence of Fibulin-1 on Hematopoietically Derived Cell Populations in Heart
Valves
Brent Wilkerson
7/1/10-6/30/12, $23,000 per year
HDL-Associated S1P in Endothelial Barrier Function and Atherosclerosis
13
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Admissions CommiAee 1st Year Progress CommiAee Assistant Dean for Global Educa;on Programs Adminstra;ve Staﬀ Business Manager Administra;ve Coordinator Administra;ve Coordinator/Assistant Director MSTP Student Services Program Coordinators II (2) Student Services Program Coordinator Creden;als CommiAee Graduate Council Curriculum CommiAee Assistant Dean for Extramural Programs 1st Year Curriculum Steering CommiAee Associate Dean for Admissions & Career Development Associate Dean Dean Provost Organizational Structure
College of Graduate Studies
Postdoctoral Associa;on Assistant Dean for Postodoctoral Aﬀairs GRADUATE COUNCIL MEMBERSHIP (’11-‘12)
Deans (non-voting members)
Perry V. Halushka, Ph.D., M.D., Dean, Chair
Jacqueline McGinty, Ph.D., Associate Dean, Department of Neurosciences
Ed Krug, Ph.D., Assistant Dean, Postdoctoral Affairs
Joann Sullivan, Ph.D., Assistant Dean, Extramural Program Development
Cynthia Wright, Ph.D., Associate Dean for Admissions
Program Directors (voting members)
* indicates co-directors with 1 vote per program rather than per person
*Lauren Ball, Ph.D., Co-director, Cell & Molecular Pharmacology
Craig Beeson, Ph.D., Pharmaceutical Sciences & 1st Year Progress Committee
Maurizio Del Poeta, M.D., Biochemistry and Molecular Biology
Victoria Findlay, Ph.D., Pathology and Laboratory Medicine
*Jennifer Isaacs, Ph.D., Co-director, Cell & Molecular Pharmacology
Laura Kasman, Ph.D., Microbiology and Immunology
*Michael Kern, PhD, Co-director, DMD/PhD Program
*Keith Kirkwood, DDS, PhD, Co-director, DMD/PhD Program
Eric Lacy, PhD, Marine Biomedicine
Marilyn Laken, RN, PhD, College of Nursing
Antonieta Lavin, PhD, Neurosciences
Donald R. Menick, Ph.D., Director, MCBP
Viswanathan Ramakrishnan, PhD, Biostatistics and Epidemiology
Arno Wessels, Ph.D., Cell Biology and Anatomy
Committee Representatives (non-voting members)
Joseph Cheng, MSTP representative
Angela Alexander, Multicultural Graduate Student Assoc.
Zack Cope, Graduate Student Association
Jaspreet Singh, PhD, Postdoctoral Association
Adam Smolka, Ph.D., Chairman, First Year Curriculum Committee
Richard Swaja, PhD, Clemson/MUSC Bioengineering
15
Graduate Admissions Committee
Members of the Committee
Name
Cynthia Wright, Ph.D., Chair
Julie Woolworth, Ph.D
Hal May, Ph.D.
Ashley Cowart, Ph.D.
Viswanathan Ramakrishnan, Ph.D.
Samar Hammad, Ph.D.
Mike Janech, Ph.D.
*Laura Kasman, Ph.D.
Joe Blumer, Ph.D.
Representing
College of Graduate Studies
Pathology and Laboratory Medicine
Marine Biomedicine
Biochemistry and Molecular Biology
Biostatistics and Epidemiology
Regenerative Medicine and Cell Biology
MCBP program
Microbiology and Immunology
Cell and Molecular Pharmacology and
Neuroscience
Pharmaceutical and Biomedical
Sciences
Bioengineering Program
Craniofacial Biology
Student Representative
Kumar Sambamurti, Ph.D.
Anna-Liisa Nieminen, Ph.D.
Hai Yao, Ph.D.
Caroline Westwater, Ph.D.
Brent Wilkerson
Anthony Parker
*co-chair
Admissions Data for 2011-2012 (as of June 22, 2012)
The College of Graduate Studies received 222 Ph.D., 38 Ph.D. Nursing, 176
M.D./Ph.D., 9 D.M.D./Ph.D., 40 M.S applications, and 7 MSCR or SPTCR applications.
For the first time we received over 200 PhD applications by our January 15 priority
deadline. The Figure below shows the number of PhD applications received by year
since 2000.
250
PhD applicants
PhD Applicants
200
150
100
50
0
2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012
Year
16
Seventy-seven PhD candidates were interviewed, 54 offers were made and 24 offers
were accepted (acceptance rate 47%). For their highest degree 8 of the incoming
students have master’s degrees, 14 have bachelor’s degrees, and two have terminal
degrees. GPA and GRE data for the applicant pool this year are displayed in the table
below. The GRE changed its scoring system in August 2011 to a different scale than
had been used previously and applicant GRE scores were received from both the old
and new scale formats. Therefore, cumulative GRE scores are reported in percentiles.
Average GPA
Average
Verbal
GRE
(percentile)
Average Quantitative GRE
(percentile)
Average Anal. Writing GRE
Total
Applicants
3.40
63.4
Offered
Acceptance
3.56
74.0
Matriculated
3.47
71.8
Declined
offer
3.64
76.2
66.5
70.0
68.0
70.8
3.8
4.1
4.0
4.2
Table 2 below displays average GPA data from 2000-2012 comparing the applicant
pools, applicants offered acceptance, matriculating students and students who declined
the offer of acceptance. For all years matriculating students had higher average GPAs
than the general applicant pool.
Total Applicants
Matriculated
Offered Acceptance
Rejected Offer
3.8
3.7
Average GPA
3.6
3.5
3.4
3.3
3.2
3.1
Year
Incoming PhD students are being supported by a variety of mechanisms. At least 5 will
be supported by training grants held by graduate studies faculty, and individual
departments or principal investigators will support 2 or more of the accepted students.
The decisions for two additional PhD applicants are still pending.
17
Efforts were made to determine where accepted PhD students matriculated if not at
MUSC. Students who declined our offer elected to attend the University of Alabama (3),
Emory University, Vanderbilt University (2), the University of Florida, the University of
Virginia, the University of California at Davis, Washington University, the University of
Maryland Baltimore County (2), the University of Washington, the University of
Wisconsin-Madison, the University of Oklahoma, the University of Pittsburgh, the
University of Illinois-Chicago, the Sanford-Burnham Medical Research Institute, the
University of Texas-Austin, Drexel University, the Max Planck Florida Institute, the
Health Science Center at San Antonio, Texas and UNC-Chapel Hill.
Offers have been made to 11 M.S. applicants. To date 4 M.S. students have confirmed
matriculation for this fall. Four offers are still pending and three offers have been
declined. To date 17 Ph.D. Nursing students will enter that program this fall.
Six large (10-12 students) PhD interview weekends were held. Thursday night a dinner
at either the dean’s home or Dr. Wright’s home was held to welcome the applicants,
allow them time to get to know each other, and meet current students. Dean Halushka
welcomed the applicants Friday morning over breakfast and presented information
about the College of Graduate Studies and the First Year Curriculum. Dr. Wright then
discussed each of the departments or programs and research areas available on
campus. After breakfast, the applicants were interviewed individually by three members
of the Graduate Admissions Committee and other faculty in their areas of interest.
Applicants also had the opportunity to tour the MUSC campus and had lunch with
graduate students. A dinner downtown with current students concluded the day,
allowing applicants to return home on Saturday, if necessary.
On Saturday, applicants toured Charleston at the College’s expense and/or returned
home. Applicants were housed at local hotels. Sixty-seven applicants were interviewed
in person and participated in the interview weekends. Ten applicants, not currently
residing in the US, were interviewed by telephone or Skype. Two of the students
interviewed by distance have accepted our offer and will matriculate this fall.
All applications were received online. Program Directors were also provided with
updates on the admissions process during the height of the admissions cycle. They
were encouraged to contact applicants who were invited to interview or were accepted.
Application materials were distributed electronically on a secured web site called
WebNow and also posted on a protected server. Interviewers and other evaluators were
able to submit their reviews of the applicants via an online form.
The figure on the next page shows the geographic demographics for the incoming PhD
class. The dots on the map indicate where students entering our class this year
received their highest degree before matriculating at MUSC. The data demonstrates
that most of our students pursued their college education in the Eastern states. Not
shown are three students who received their highest degrees in China, France, or Italy.
18
Recruitment
Many recruitment trips were made by College of Graduate Studies faculty. Dr.
Wright hosted a recruitment table at the annual NIH grad fair in July 2011. In
addition, informational/recruitment trips were made to the University of Maryland
Baltimore Campus and the College of Charleston MUSC night. Dr. Wright and
students in the Multicultural Graduate Student Association (MGSA) made
additional trips to Claflin University and to Charleston Southern University’s
MUSC night. Faculty and students from MUSC also attended the Annual
Biomedical Research Conference for Minority Students (ABRCMS) in St. Louis,
MO and the annual Society for Advancement of Chicanos and Native Americans
in Science (SACNAS) in San Jose, California, hosting recruitment tables at both
venues. Dr. Halushka met with student advisors who attended the E.E. Just
Symposium to inform them about our program and to answer questions. Dr.
Wright and current graduate students met with students who attended the
symposium to talk about how to apply to graduate school and to answer
questions about graduate student life. At all of these venues we provided flyers,
CDs, and other recruitment materials appropriate for disseminating information to
potential summer students, graduate students and postdoctoral fellows. In
addition, the College of Graduate Studies office mailed over 200 packets of
recruitment information to the RISE, MARC U*STAR, and McNair program
Directors, to 460 McNair Scholars (science majors), and to approximately 4,500
19
individuals who took the GRE last year. The office also coordinated large
mailouts of recruitment materials nationwide to students taking the MCAT exam
to advertise our MD/PhD program.
Web Site
The College’s website has continued to be improved and developed. This year the
defense announcements for students were made available on the front page of the
website along with abstract information for each project. The format for the website
will continue to be updated in accordance with MUSC’s web standards
Career Development
The summer pre-matriculation course remains a strong component of our graduate
program. Last year 13 out of 29 matriculating students took the summer course. The
course takes place in mid-summer for four weeks and all matriculating graduate
students are welcome to enroll. PhD students’ stipends are started at this time. There
are two hours of morning lecture followed by afternoons either doing a lab rotation of the
student’s choice or participating in our laboratory techniques course.
The IMSD training program in collaboration with the MGSA sponsored Dr. Tom
Smith of the MUSC Center for Academic Excellence who gave a workshop on
November 21, 2011 with tips and advice for how to prepare a CV. The workshop
was open to all students, faculty, postdocs, and residents. The College of
Graduate Studies also hosted Dr. Linda Harris from St. Jude Children’s Research
Hospital who came and discussed postdoctoral research opportunities at St. Jude
on December 8, 2011.
Goals
1. Continue to evaluate and improve the criteria by which applicants are admitted to the
College of Graduate Studies.
2. Continue to recruit the highest quality Ph.D. students using recruitment scholarships
and improved advertising.
3. Continue to update the website of the College of Graduate Studies.
4. Increase the number of domestic Ph.D. applicants by 15%.
5. Continue to improve the environment of the College by hosting career development
opportunities.
20
Credentials Committee
Dennis K. Watson, Ph.D., Chair
Pathology & Laboratory Medicine
Yiannis Koutalos, Ph.D.
Ophthalmology
Elaine Amella, BSN, Ph.D.
Nursing
John Woodard, Ph.D.
Neurosciences
Accomplishments during the past year
Over the 2011-2012 academic year, the Credentials Committee reviewed 65
applications and made recommendations for the appointment of 17 (40%) individuals for
Full Membership and 48 (60%) individuals for Associate Membership. The number of
applications reviewed increased from that of 2010-2011 when 51 applications were
reviewed. In addition, 44 applications were reviewed for reappointment for Full
Membership and 24 applications for Associate Membership and 1 application for
reclassification.
Goals for the coming year
Continue to review applications in a timely manner to provide the opportunity for all
interested individuals to become a member of the Graduate Faculty.
Maintain uniform standards for approval of faculty as Associate or Full membership.
21
Curriculum Committee
The Curriculum Committee is responsible for the evaluation and approval of all didactic
courses offered to students in all graduate departments and programs. This includes
constituent courses of the First Year Curriculum and advanced courses in subsequent
years. The Committee reports all new and revised courses to the Graduate Council.
Membership
The Committee membership consists of faculty representatives of graduate
departments and programs. Each graduate program is represented by one member and
an alternate who are chosen by their respective chairs. Only the member has a vote;
however if the member is absent then the alternate may vote. Each member serves a
term of two years. The director of the first year curriculum is also a member of the
Committee and has one vote. There is also one student representative chosen by the
Graduate Student Association who serves for a term of one year. The members of the
Committee elect the chairperson and vice-chairperson. The latter presides over the
meetings in the absence of the chairperson.
Adam Smolka, Ph.D., Chair
Medicine
Jillian Johnson
Graduate Student Representative
Carl Atkinson, Ph.D.
Microbiology & Immunology
Jennifer Isaacs, Ph.D.
Cell & Molecular Pharmacology
Howard C. Becker, Ph.D.
Psychiatry
R. Amanda C. LaRue, Ph.D.
Pathology and Laboratory
Medicine
Thomas A. Dix, Ph.D.
Drug Discovery and Biomedical Sciences
Robin Muise-Helmericks, Ph.D.
Regenerative Medicine & Cell
Biology
Valerie Durkalski, Ph.D.
Biostatistics, Bioinformatics & Epidemiology
Cheryl Woodley, Ph.D.
MCBP, Marine Biomedicine
Mirko Hennig, Ph.D.
Biochemistry & Molecular Biology
Keisha Vaughn
Administrative Liaison
Meeting Schedule
Three meetings per year: last week of January (for summer semester courses), last
week of April (for Fall semester courses), and last week of August (for Spring semester
courses). Guidelines for course design and committee procedures for course evaluation
are detailed in the College of Graduate Studies Curriculum Committee web-page
(http://www.musc.edu/grad/faculty/curriculum.html). To expedite the approval process,
22
some links and templates that course directors may find helpful are included. This
information will serve to standardize the course review process and convey the
Committee's minimum requirements for approval. To expedite the course approval
process, the web-page includes templates and links that course directors may find
helpful. This information will serve to standardize the course review process and convey
the Committee's minimum requirements for approval.
New Courses Approved for 2011-2012
Course #
Course Title
BSC 700
Histology
Course Director
Semester
Hours
Robert Ogilvie
Roger Sawyer
Summer
4
BSC 702
Anatomy
Theirry Bacro
Fall
4
BSC 704
MCAT Prep
Jenny Ariail
Summer
3
BSC 706
Professional Development
Jenny Ariail
Wanda Taylor
Cynthia Wright
Summer
1
BSC 708
Grand Rounds
Laura Kasman
Cynthia Wright
FA/SP/SU
1
BSC 710
Clinical Exposure
Perry Halushka
FA/SP/SU
1
BSC 712
Comprehensive Biochemistry
Lee Chao
Fall
3
BSC 714
Oral Immunobiology
Caroline
Westwater
Spring
4
BSC 716
Medical Microbiology
Mike Schmidt
Spring
4
CGS 729
Biomedical Commercialization
Mark Kindy
FA/SP
3
Andrea Summer
Fall
2.5
L.W. Preston
Church
Terry C. Dixon
Spring
2.5
MCBP
MCBP 748 Lipids in Pathobiology
Samar Hammad
Spring
3
MCBP 749 Marine Organismal Health
Karen Burnett
FA/SP
1
Global Health
GH 700
Topic in Global Health
GH 702
Tropical Infectious Diseases
23
MCBP 780 Vision and Ocular Diseases
Shahid Husain
FA/SP
1
MCBP 782 Cardiovascular Biology Journal
Club
Don Menick
FA/SP
1
Dan Lackland
Fall
1
Charlene Pope
Fall
3
Pathology
PATH 781 Topics in Cancer
Dennis Watson
FA/SP
1
Course Changes Approved:
CGS 720
Laboratory Rotation
Jakie McGinty
Fall
2
MCBP
MCBP 724 MCBP Seminar
Don Menick
FA/SP
1
Masters in Clinical Research
MCR 700 Clinical Epidemiology
Tom Hulsey
Fall
3
MCR 736
Clinical Epidemiology
Tom Hulsey
Fall
3
MCR 744
Molecular Approaches to
Experimental Medicine
Tom Hulsey
Spring
4
Laura Kasman
Cynthia Wright
Fall
3
MBIM 617G Infection
Laura Kasman
Cynthia Wright
Spring
4
MBIM 614
Immunity
Laura Kasman
Fall
3
MBIM 735
Molecular & Cellular Basis
of Inflammation and Immunity
Carl Atkinson
FA/SP
3
MBIM 856
Critical Literature Review
in Inflammation and Immunity
Natalie Sutkowski FA/SP
1
Masters in Clinical Research
MCR 750 Ethical Issues in Clinical
Research I
Nursing
NRPHD
Advanced Research Study
Design and Methods
MBIM 616G Infection
24
Distinguished Graduate Of The Year Commitee
Perry V. Halushka, PhD, MD, Chairman
Joe Blumer, PhD
Department of Pharmacology
Thomas Dix, PhD
Department of Pharmaceutical
Sciences
Sergey Krupenko, PhD
Department of Biochemistry and
Molecular Biology
Daniel Lackland, DPh
Department of Biostatistics,
Bioinformatics and Epidemiology
Antonieta Lavin, PhD
Department of Neurosciences
Donald Menick, PhD
Department of Medicine
Steven Rosenzweig, PhD
Department of Pharmacology
Cynthia Wright, PhD
Accomplishments for 2011-2012
The committee reviewed 8 outstanding applications. For the first time, the committee
unanimously agreed to award co-recipients of the Distinguished Graduate of the Year based
on the tremendous number of accomplishments made by both Russell Jenkins, MD, PhD
and Khaled Moussawi, MD, PhD. Their mentors were Yusuf Hannun, MD and Peter Kalivas,
PhD, respectively. Russell’s and Khaled’s names will appear along with all the previous
distinguished graduates on a plaque outside of the College’s office suite. They each
received a plaque with their name on it at the College’s annual awards luncheon and will
return in the Fall to present the annual Liz Chesterman Memorial Lecture to the incoming
graduate students. They will each receive an honorarium of $500 at that time. Two other
graduates were deemed as outstanding and were chosen as finalists. They received a
plaque and a check for $250. The finalists were:
Matthew Pava, PhD
Mentor: John Woodward, PhD
Thomas Mullen, MD, PhD
Mentor: Lina Obeid, PhD
Goals for 2012-2013
Our goal as in previous years, is to have a higher percentage of the graduates nominated
for the award. Endow the Liz Chesterman Lecture.
25
First Year Curriculum Steering Committee
Adam J. Smolka, PhD, Chair
Craig Beeson, PhD
Ashley Cowart, PhD
Maurizio Del Poeta, MD
Scott Eblen, PhD
Pharmaceutical & Biomedical Sciences
Cell and Molecular Pharmacology &
Dean, College of Graduate Studies
Regenerative Medicine & Cell Biology
Marine Bioscience
Neurosciences
Medicine/Cardiology
Pharmaceutical & Biomedical Sciences
Cell and Molecular Pharmacology &
Student Principal
Student Alternate
Debra Hazen-Martin, MD
Perry Halushka, PhD, MD
Laura Kasman, PhD
Ed Krug, PhD
Eric Lacy, PhD
Jacqueline McGinty, PhD
Don Menick, PhD
Kennerly Patrick, PhD
Steve Rosenzweig, PhD
Cindy Wright, PhD
W. Jim Zheng, PhD
Sarah Barrett
Theresa Cantu
Committee Accomplishments for 2011-2012
The Steering Committee oversaw the eleventh implementation of the First Year
Curriculum since 2001. Twenty-eight graduate students were instructed by thirty-seven
faculty lecturing in eight Units of two Foundations of Biomedical Sciences courses (CGS
701 and 702), and by comparable number of faculty teaching or otherwise participating
in five other elements of the First Year Curriculum (Essentials of Scientific Practice,
Laboratory Rotations, Spring Selectives, Important Unanswered Questions, and
Program Exposures). A First Year Curriculum Retreat held June 29th, 2011, attended
by a majority of FYC faculty, yielded a series of proposed changes to the curriculum
which were subsequently approved by the Steering Committee meeting July 28th, 2011.
Curriculum adjustments included revision of CGS 701/702 in-Unit assignment grading
(25% of Unit grade), three Laboratory Rotations, of which two are required to be in
different labs, debut of a "First Year Research Rotation Day", at which all FYC students
are required to present their Lab Rotation projects, student completion of E*Value
evaluations before posting of Unit grades, re-structuring of the Systems Biology Unit,
improved coordination of Nucleic Acids and Gene Expression Units, and implementation
of 9:00 am start time for Unit lectures.
26
Committee Goals for 2012-2013
In keeping with the Committee's charter, goals for the coming year are continued
evaluation, revision, and evolution of the curriculum. The committee will consider a
transition from a strictly lecture-based didactic format in CGS 701/702 in favor of
discussion-based tutorials. As in previous years, emphasis will be placed on recruitment
of new faculty to ensure the highest quality of teaching and to keep curriculum content
abreast of advances in biomedical sciences.
27
First Year Progress Committee
Craig C. Beeson, PhD
Pharmaceutical Sciences
Physiology and Neuroscience
Christina Voelkel-Johnson, PhD
Robin C. Muise-Helmericks, PhD
Cell Biology and Anatomy
Arno Wessels, PhD
Cell Biology and Anatomy
Joyce Nicholas, PhD
Biometry and Epidemiology
Cynthia F. Wright, PhD (ad hoc)
Pathology and Laboratory Medicine
Besim Ogretmen, PhD
The First Year students performed well in the Fall curricula with an average GPA
of 3.5 with a S.D. of 0.3 and only one student with a GPA below 3.0 for CGS 701.
The First Year students also performed reasonably well in the Spring curricula
with an average GPA of 3.5 with a S.D. of 0.4. In this case there were two
students with a GPA below 3.0 for CGS 702. However, both had cumulative
GPA grades of 3.1 and, thus, completed the semester satisfactorily. All students
performed well in the seven week selectives. Last year, one student completed
the year with an overall GPA of 2.8. The student, a member of the
Neurosciences program, had appealed the required dismissal from the PhD
program and the Progress Committee offered to have him repeat CGS 701.
However, he was not successful in bringing his GPA to ≥ 3.0 and the committee
ruled that he not be allowed to continue in the program. As per his rights, he
appealed the decision and with support from the Neurosciences program, he has
been give another year to be in compliance with the minimal GPA requirement –
overall, his academic performance and research has been otherwise exemplary.
Goals for 2012-2013
The first half of the curricula in CGS 701 and the Important Unanswered
Questions is evolving to encourage more active learning and the FYC Progress
Committee hopes to facilitate the evolution via advising of the students. The
Progress Committee is also developing a program for the orientation of the
incoming students to advise them about the process of mentor selection and this
program will be incorporated into the second day of classes.
28
Office Of Postdoctoral Affairs
Edward Krug, PhD
Assistant Dean for Postdoctoral Affairs
Demographics of the MUSC Postdoctoral Community:
•
•
•
•
There are currently 201 scholars (48% US/52% international) at MUSC across 4
colleges.
The international postdocs represent 29 different countries (28% from China; 35%
from India).
41% of the US/permanent resident postdocs are supported by either individual
fellowships or training grants.
The staff scientist classification continues to be a viable next step for postdoctoral
trainees. There are currently 32 researchers across the 3-tiered, scientist
classification.
Involvement of the Office of Postdoctoral Affairs in University Activities:
•
•
•
•
•
Assisted in restructuring of the International Support Office to facilitate global
outreach efforts by MUSC faculty.
Represented the College of Graduate Studies on the MUSC Biochemistry Chair
Search Committee.
Appointed Chair, MUSC Research Integrity Committee.
Appointed to the MUSC Conflict of Interest Steering Committee.
Invited speaker at the College of Medicine Mentor Training Program, May 2012.
Presentation entitled, “Mentoring Basic Science Trainees”.
Involvement of the Office of Postdoctoral Affairs in Local and National Activities:
•
•
•
•
•
Chair-elect of the AAMC Graduate Research, Education, and Training (GREAT)
Group for Postdoctorate Leadership Section.
Facilitated MUSC being selected as host for the National Postdoctoral Association
Annual Conference in March 2013.
Invited speaker at the “What Can You Be with a PhD?” conference at New York
University Langone Medicine Center, November 2011. Panel moderator, “What the
Future Holds: Careers in Teaching and Education”. Panel participant, “Getting the
Most from Your Mentor”.
Invited speaker at the Charleston Chamber of Commerce on International
Research Collaborations, January 2012. Presentation entitled, “Internationals in
the US Biomedical Workforce”.
Invited speaker at the National Postdoctoral Association Annual Conference in San
Francisco, CA, March 2012. Presentation entitled, “Partnerships Between NIH
IRACDA Postdoctoral Fellows and Minority Serving Institutions”.
29
•
Poster presentation at the National Association of Foreign Student Advisors
Annual Conference in St. Louis, MO, May 2012.
Goals for 2011-2012
•
•
•
•
Completion of the CGS Postdoctoral Policy Manual
Establish a 5 year limit for postdoctoral appointments
Establish a Postdoctoral Training Advisory Committee
Revision of the Office of Postdoctoral Affairs website
30
Perry V. Halushka MUSC 2011 Student Research Day
Steven Kubalak, Ph.D., Chair
Regenerative Medicine and Cell Biology
Names
Christopher Davies, Ph.D.
Thomas Dix, Ph.D.
Teri Lynn Herbert
Paul Jacques, D.H.Sc
Teresa Kelechi, M.S.N., Ph.D.
Maralynne Mitcham, Ph.D.
Susan Reed, Ph.D.
Michael Schmidt, Ph.D.
Debbie Shoemaker
Zachary Cope
Elizabeth Little
Vondina Brown
Representing
Education Center & Library
College of Health Professions
College of Nursing
College of Dental Medicine
Committee Accomplishments for 2011-2012
The 46th annual Perry V Halushka-MUSC Student Research Day was held on Friday,
November 4th 2011. There were 254 presentations (88 podium and 166 poster) were
delivered in a total of 20 scientific sessions. The total number of abstracts presented
was a new record number for SRD. Presenters represented all six colleges of MUSC
and were drawn from:
1. Undergraduate and High School students who had participated in the MUSC
summer research programs including the Summer Undergraduate Program and
the South Carolina Governor’s School for Science and Mathematics Program
2. Health Professional and Masters students including medical and dental student
participants in the MUSC Summer Health Professions Research Program,
Master’s program students including College of Health Professions and College
of Graduate Studies students and students from the Colleges of Pharmacy
3. Ph.D. students representing all six colleges and virtually every basic science and
clinical department at MUSC
4. Clinical Residents and Fellows
5. Postdoctoral research fellows
Poster sessions were held in the Harper Student Center Gym from 8:30 am to noon and
oral sessions were held in the College of Health Professions building from 11:00 am
until 3:30 pm. Concurrent with the poster sessions in the Gym there was a commercial
Vendor Show attended by 17 scientific research equipment and supplies exhibitors.
Student Research Day is highlighted by the keynote lecture, this year delivered by Dr
Mark Sussman. Dr Sussman is a Distinguished Professor of Biology and Chief
Research Scientist at the San Diego State University Heart institute in San Diego, CA.
31
He is also Chair of the Basic Science Council on Cardiovascular Research of the
American Heart Association. He is world renowned for his significant contributions to
pediatric and adult cardiovascular research and is currently also making significant
contributions to stem cell research. The title of the SRD 2011 Keynote Lecture was
“From Sarcomeres to Signaling to Stem Cells” and was extremely well-received by all
who attended. This was followed by a catered reception at 5:00 pm in the Lobby of the
Drug Discovery Building to commemorate the entire day.
Teams of faculty and selected postdoctoral fellows judged presentations. A total of 89
MUSC faculty and 4 select postdoctoral fellows participated as judges – organized into
teams of three. SRD 2011 culminated with the awards ceremony at which 20 first place
prizes of $500 and 20 second place prizes of $200 were awarded. The Graduate
Alumni Association presented the Kinard-Gadsden Award for outstanding poster
presentation in the senior Ph.D. category and Sigma Xi presented awards for the best
oral and best poster presentations from a Sigma Xi member. Multiple awards were also
presented to winners in the categories of Health Disparities, Interprofessional
Collaboration, Charleston Chapter Research Award, and Ralph H. Johnson VA Medical
Center Award. SRD 2011 marked the fifth year in which the Eric R. James Award was
given for the 1st place PhD VII oral presentation – in honor of Dr James’ 20 years of
service as the chair of MUSC Student Research Day. Another prestigious award is the
Willard & Betty Peterson Award given for the 1st place PhD VIII oral presentation.
Sponsorship for SRD 2011 was provided by contributions from the Vice President for
Academic Affairs and Provost, the Deans of the Colleges of Dental Medicine, Graduate
Studies, Health Professions, Medicine and Pharmacy as well as the Graduate Alumni
Association and the 17 corporate participants.
•
•
•
•
•
•
•
Enhance the MUSC Research Day website to be more interactive for participants,
faculty, judges and vendors, and include information and links for the Postdoctoral
Association.
Keep the Keynote Lecture and reception in the new Drug Discovery Building.
Move the highest PhD Oral Presentation session, which bestows the Willard and
Betty Peterson Award to the overall best PhD oral presentation, to the new
Bioengineering Building classroom (BE112).
Begin using the new name for the day: Perry V Halushka MUSC Research Day to
better reflect the diversity of participants across them MUSC campus (Student was
dropped from the title).
Further improve the efficiency of the day with the aim of creating the best Research
Day ever.
Better streamline the organization of the vendor show including the establishment of
a web-based registration option for vendors.
Recruit a prominent woman scientist for the 2012 MUSC Research Day Keynote
Speaker and coordinate a portion of the Day’s activities with the MUSC Woman
Scholars Initiative.
32
Graduate Student Association
Members of the Executive Committee
Zackary Cope
President
Emily Allen
Vice President
Kayla Hill
Secretary
Jake Alsarraf
Treasurer
Social:
•
•
•
•
•
•
•
•
Summer Happy Hour: ~45 attendees
New Student Social: ~130 attendees
Fall Happy Hour:
PhD Movie Screening: 89 RSVPs, 95 attendees
Ugly Christmas Sweater Party: ~60 attendees
Cocktail Party: ~150 attendees
Spring Happy Hour: 40 attendees
Spring Picnic: 170 attendees
Service:
366 total community service hours logged by GSA members at:
 Charleston Campus Hope Lodge
 Martin Luther King Day of Service Health Fair
 AMSA Sugar Free Fall Festival
 Charleston Area Senior Center
$1209 in total charitable contributions to:
 Fields to Families
 Charleston Area Children's Garden Project
 Relay for Life
Four (4) $500 Travel Awards to CGS Students
Outreach:
Graduate students Reaching Out With Science (GROWS)
25 student participants
182 hours of volunteer teaching at:
• Military Magnet Academy
• West Ashley Middle School
• Montessori
33
Fundraising:
Performed 18 board movings totaling $25,330.52 in revenue for GSA
Net expenses: $29,131.04
Remaining Balance: $2,234
Social:
•
•
•
Grow faculty/staff attendance at social events
Maintain high student attendance and participation at these events
Add more variety to the social event calendar (i.e. breakfast socials,
outdoor activities)
•
•
•
Increase the number of participants in service activities
Add additional service activities for the calendar year 2011-2012
Raise awareness among students of service activities outside of GSA (i.e.
Fields to Families)
Expand the GROWS Program to training middle school students at
MUSC’s Urban Farm
Service:
•
Outreach:
•
•
Continue to expand the GROWS program to at least 20 participants and
100 hours contributed
Expand GSA to include a committee geared toward graduate student
recruitment and retention
Fundraising:
• Continue our high volume of board moving service
• Grow GSA member participation in this service
34
Multicultural Graduate Student Association (MGSA)
Mission
This year, the Multicultural Graduate Student Association continued in our mission to
improve the well-being of ALL graduate students within the College of Graduate Studies
with special attention given to students from diverse backgrounds. We achieved and
exceeded our goals this year through our project R.E.A.C.H. initiative. The aims of
Project R.E.A.C.H. are to: recruit minorities to the College of Graduate Studies Master's
and Ph.D programs, enrich the members of MGSA, MUSC, and Charleston community
socially, culturally, and professionally, advocate communication with other students and
faculty within the college, cultivate an interest in the biomedical sciences amongst
minority students in Charleston area schools, and help underrepresented and
underserved Charleston communities through outreach projects.
Accomplishments
MGSA has been very successful in the 2011-2012 academic year. We have exceeded
what we set out to accomplish. A summary of our accomplishments is listed below:
 Won MGSA Gives Back Award for the College of Graduate Studies!
 Accumulated over 500 hours of community service!
 Hosted our first annual school-wide World Aids Day program
 Continued on-going volunteer effort at the Carolina Youth Development Center
 Established REACH for the STARS college mentoring program
 Started tutoring program in collaboration with Mt. Moriah Church
 Attended the National Black Graduate Student Association Conference
 Hosted dynamic monthly career development workshops
All of the accomplishments and activities of MGSA over the past year are described in
detail in the following sections, divided according to the project R.E.A.C.H. aim that
each activity fulfills.
Mentoring Programs
MGSA Summer Undergraduate Research (SURP) Forum
One of the primary purposes of MGSA is to enhance the interest of undergraduate
students in the biomedical sciences and research, with a special emphasis on
underrepresented minorities. By hosting events like the Annual MGSA SURP forum, we
are able to expose undergraduate students to the opportunities that await them upon
the completion of their bachelor’s degrees.
This past July, the panelist for the forum consisted of speakers from the six colleges
here at MUSC. Members of the panel discussed the admissions process and academic
requirements at MUSC.
Students from the College of Medicine discussed the
competitiveness and importance of good academic and MCAT scores, while students
from the College of Graduate Studies stressed the importance of previous research
experience.
35
Students and their faculty mentors commented about the encouragement and insight
that students gained from panelist and leaders of MGSA. Prior to the forum, students
mentioned that they were unclear about the differences and admissions requirements
between graduate school and the medical school.
Panelists were able to clearly
explain the differences between all of the different programs offered at MUSC.
Moreover, undergraduate minority (URM) students gained courage and confidence to
apply to graduate programs because they were able to meet graduate students who
were minorities and who could relate to them on a cultural basis.
Through this forum, we were able to affect change within the scientific community. We
not only influenced URM and other undergraduate students to make decisions about
seeking higher education in the biomedical sciences; but, we were also able to provide
hope to students that may have lacked confidence in their abilities to succeed at the
graduate level. Through sharing our experiences and successes, we were able to
impart “life” to the dreams and hopes of others.
Ernest E. Just Symposium
MGSA members continue to participate in the E.E. Just Symposium. This symposium
is hosted by MUSC annually to encourage underrepresented students to pursue careers
in the sciences and health professions. MGSA members participated in a lunch panel
discussion where we spoke to undergraduate students about pursuing graduate
degrees in the sciences. During this panel discussion we talked about the benefits of
pursing graduate degrees in the sciences and dispelled any misconceptions the
students had about pursing graduate degrees. We also gave lab tours to the students
following the panel discussion.
R.E.A.C.H for the S.T.A.R.S
This year MGSA wanted to focus on developing the “C”, cultivate, and “H”, Help,
initiatives under our Project “R.E.A.C.H” mission. We used our mentoring program to
cultivate an interest in the biomedical sciences amongst undergraduate institutions, and
to help youth attending an after school care program achieve better grades and broaden
their outlook for their future. The acronym for the undergraduate mentoring program
“R.E.A.C.H for the S.T.A.R.S: Recruit, enrich, advocate, cultivate, and help minority
students to start training as researchers in sciences encompasses the overall goal of
the program. We attended 3 undergraduate institutions this year: Claflin (September 5,
2011), Charleston Southern University (February 15, 2012), and the College of
Charleston (March 27, 2012). At each visit, we presented a workshop about the pursuit
of higher education, the different “colors” of science, how to find graduate/professional
schools that are right for you, and reasons why pursuing higher education broadens the
outlook of your future. We also held a panel composed of MGSA members that took
questions from the students regarding graduate school life, admittance, and how to
prepare. Lastly, we gave out information on how to contact us and invited students to
MUSC where they could participate in a shadowing opportunity in the life of a graduate
student. As a result of, our efforts one student did apply to the Graduate School at
MUSC.
36
Career Development Workshops
Our professional and career development events were used as tools to enrich our
members and provide an opportunity for members to interact with faculty. They were
primarily held during our monthly general body meetings.
How to Give a Scientific Presentation
Deanna Baker a MD/PhD student and member of MGSA conducted this workshop. She
spoke to the members about the proper way to present a scientific presentation,
powerpoint or poster.
Preparing for Student Research Day: Practice Makes Perfect
In order to perfect the tips gained in our first workshop of the year, presented by
Deanna Baker, a follow up workshop allowed members to practice their presentations
for the Annual Perry Halushka Research Day. Three members practiced either oral
(powerpoint) or poster presentations for the following reviewers: Grace Wallenborn,
PhD, Santhosh Mani, PhD and Adam Smolka, PhD. Each presenter was reviewed
based on the same guidelines that govern the judging of research day and in-dept
feedback and recommendations were provided. As a result, two attending members
won 1st place in their respective categories.
CV Writing: Tips from the Pros
This workshop was organized by Dr. Cynthia Wright based on the feedback that she
received from several graduate students in the CGS. Tom Smith, PhD from The Writing
Center (Center for Academic Excellence) provided very clear detailed instructions and
examples concerning the proper formatting for a curriculum vitae. This workshop was
open to the entire campus and approximately 25 students attended.
Networking at Conferences
Dr. Edward Krug provided insight on the ins and outs of the proper way of networking at
scientific conferences. He provided us with appropriate advice concerning the major
points of networking.
Potential Career Choices: Industry versus Academia
Drs. Craig Beeson and Robert Gourdie spoke to the organization about their
experiences in both academics and industry. Members were extremely interested in
understanding their reasons for pursuing their chosen paths in life. Questions were also
asked concerning the benefits associated with industry and academia. The information
provided stimulated much conversation and reflection among the members.
Preparing for Qualifying Exams/ Journey to Defending
This workshop was conducted as a panel discussion; the panelists included several
current MGSA members (Vondina Moseley, Denise Kimbrough, Joy Jones Buie) and
one research assistant professor (Sundar Balasubramanian). The panelists were
chosen based on their positions in their course of study (passed qualifying exam and
preparing dissertation) and their association with the generation of the questions that
compose one program’s (MCBP) written qualifying exam. Members asked questions
37
associated with preparations, how to successfully answer the written exam questions,
what to expect during orals and what steps should be taken to compose the chapters of
a thesis.
From School to Work
The last career development workshop of the year was presented by an alumnae of
MUSC, Shantae Jenkins, MD, PhD. In this workshop Dr. Jenkins gave the MGSA
members advice on what should be taken into consideration when deciding what career
path they should take following completion of their degrees. She presented traditional
and nontraditional career pathways that many doctoral students decide to purse. The
members were very interested and conversation was stimulated, but one of the main
points Dr. Jenkins stressed was that we should all remain true to our ‘authentic self’.
Social Events
MGSA planned social events with the intent of fostering more interest in our
organization and promoting the development of relationships amongst members within
the organization.
Bowling Night
MGSA invited new members of CGS and summer students out for a night of food,
fellowship, and fun at a bowling alley. MGSA members had the opportunity to meet and
greet new graduate students and answer questions about the upcoming school year.
Ice Skating
Members of MGSA and their families wanted to do something different than the normal
bowling and dinner. So to get exercise and some fun we decided to try ice-skating at
Carolina Ice Palace. For two hours we fell, laughed and fellowshipped with each other
while becoming closer colleagues. The total attendance at this event was 10 members
and friends.
Super Bowl Party
The purpose of the super bowl party was to serve as a social event for the organization.
During this event, MGSA purchased chicken wings and pizza and members donated all
other side items. The event was held in Gazes auditorium. It was designed as a time
for members to unwind and get to know each other as well as family members of
members of the organization.
Ice Cream Social
To welcome in the new students of the CGS, MGSA also sponsored an ice cream social
in the healing Gardens located in the Hollings Cancer Institute at the beginning of the
year. This event was designed to introduce those students who were not here during
the summer to MGSA and benefits of joining the group. They got a chance to meet
MGSA members whom could possibly help them during the pursuit of their degrees.
38
Outreach Activities
One of MGSA’s goals is to help the community in any way that we can. This year we
continued some of our old programs and also began new ones that we plan to continue
in the future. In addition to other outreach programs, our goal this year was to start new
outreach initiatives with a health-related focus.
Carolina Youth Development Center (CYDC)
MGSA continued our on-going community outreach project for our second year
volunteering at the North Charleston campus of the Carolina Youth Develop Center
(CYDC). The CYDC North Charleston Campus serves youth ages 10‐21 and provides
shelter for children that have been neglected or abused. Each month, MGSA members
travel to the CYDC and cook hearty nutritious meals for the children. We also provide
games, help with homework, and mentor the children. We also hosted our second
annual end-of-year cookout celebration at the CYDC this year. We hosted this event to
celebrate the achievements of the children and wish them a great summer. We
thoroughly enjoy volunteering at the CYDC and plan to continue our projects with them.
Sugar Free Fall Festival (SFFF)
MGSA continues to participate in the SFFF hosted by MUSC Gives Back. This year, we
provided a bean bag toss, coin-sliding game, and plenty of prizes for the children who
participated.
Christmas Basket Delivery
MGSA continued to participate in a Christmas basket delivery in collaboration with St.
Matthews Lutheran Church during this past holiday season. Members of the church
assembled the baskets, which included items such as robes, blankets and toiletries.
MGSA members delivered these baskets to homes of elderly citizens of downtown
Charleston. We enjoyed showing our appreciation to the elderly by bringing them a little
holiday cheer.
MLK Day Health Fair
Similar to last year, MGSA collaborated with the graduate student association (GSA) in
creating a booth for the health fair. Our booth included heart and brain health. MGSA
was responsible for heart health info and GSA created the brain health info. We
showed a human heart and brain to the attendees, who had an opportunity to actually
touch the organs (wearing gloves, of course). We also showed tissue slides on a
microscope of heart and brain samples. MGSA enjoyed participating in the event and
collaborating with GSA. It was exciting to present information at a health fair from the
non-clinical perspective that the graduate students have. The health fair participants
seemed to really enjoy participating in hands-on science.
World Aids Day
In an attempt to address the ever-growing concerns of the transmission of HIV/AIDS,
MGSA in collaboration with the MUSC Center for Infectious Disease HIV/AIDS Clinic,
Global & Tropical Medicine Interest Group (GTMIG) and MUSC Gives Back hosted two
days of events focused on educating the public and members of the student body. The
39
first event, a panel discussion entitled, “Living with HIV”, was composed of three HIV
positive individuals. These individuals spoke candidly and honestly concerning various
aspects of living with HIV, ranging from diagnosis, treatment to dating. That evening Dr.
Christopher Moore from University of Virginia School of Medicine gave a presentation
about the global impact of AIDS entitled: “AIDS in Sub-Saharan Africa: Past, Present,
and Future”. Immediately following Dr. Moore’s lecture, a reception was held offering
light snacks and safe-sex themed drinks. Also, on that evening, members of MGSA
attended the Annual Community Vigil at the College of Charleston Cistern.
On December 2, 2011, HIV testing was provided by Lowcountry AIDS Services (LAS).
Testing was conducted in a very private setting and all information was confidential and
kept private. This was done to stress the importance that all individuals should know
their status. Free condoms were also provided at all events, in an effort to encourage
safe sex.
Ribbons were sold at all events and the proceeds were given to LAS, to help with their
efforts to educate and protect.
Party for A Purpose
In order to continue to raise funds for MGSA’s work with the CYDC, a new source of
fundraising was explored. In collaboration with Mad River Bar and Grille located in
downtown Charleston, we hosted “Happy Hour for a Cause”. This event was advertised
campus wide. Free food and drinks were offered as incentives for student support. All
proceeds (cover charged) supported our efforts at the CYDC.
Go Red for Women
Cardiovascular disease is the leading causes of death among women in the U.S. Every
year, the number of women suffering from heart attacks and cardiovascular disease
increases. This year, MGSA wanted to raise awareness of this issue by going RED for
women’s heart health. In honor of Women’s Heart Health Month, we asked that
students join us on Friday, February 3rd in support of American Heart Association
National Wear Red Day. We also distributed healthy heart shaped cookies along with
information about heart health around campus.
Chick-Fil-A Spirit Night
MGSA hosted a Spirit Night at Chick-fil-A to raise funds for the CYDC. Our Spirit Night
was held at Chick-fil-A located at 1656 Savannah Highway. Ten percent of all profit
received by Chick-fil-A was given to MGSA in support of our efforts at the CYDC. We
raffled off two gift baskets to those who supported the event.
Meeting Attendance
MGSA had a total of 5 officers this past year and 13 members of the general assembly.
Figure 1 shows our monthly general assembly attendance records. Our members
included (in alphabetical order): Angela Alexander*, Jake Alsarraf, Fahmin Basher,
Danielle Brandon, Robert Bryant, Joy Buie, Christy Cassarly, Danielle Clark, Nortorious
Coleman, Melanie Davis, Kayla Hill, Denise Kimbrough*, Vondina Moseley, Sybil
40
Nelson*, Dorea Pleasant*, Jessica Ross*, Christopher Smith, Raquela Thomas and
Dr. Cynthia Wright*.
*Indicates Officer or Advisor
Figure 1 General Assembly Meeting Attendance
Revenue
MGSA had a starting budget of $1500 this year through CGS, an increase of $500 from
last year’s budget. Of this funding, $1000 was allotted to community service and $500
was allotted to our operational budget. We also received $2,150 for conference travel
for the National Black Graduate Student Association Conference. We exhausted all of
the funding we received. We were also able to rasie additional funding through
fundraisers and membership dues ($20), which were kept in our First Federal account.
Figure 2 reflects our withdrawals and deposits on a month-by-month basis, while figure
3 shows the resulting balance for each month.
Figure 2 Withdrawals and Deposits
Figure 3 Monthly Balance
MGSA Spending for the 2011‐2012 Fiscal Year
2011‐2012 Month‐to‐Month Account Balance
$1,000
$900
$1,000
$800
$900
$800
Monthy Deposits
Monthly Withdrawls
$500
$400
$700
US Dollars
$600
$600
$500
$400
$300
$300
$200
$200
$100
$100
41
ay
M
ril
ch
Ap
ar
y
ar
M
br
u
ar
y
Month
Month
Fe
be
r
m
ce
De
Ja
nu
r
r
be
m
No
ve
r
be
Oc
to
be
em
Se
pt
Ju
ly
Au
Ap
ril
gu
st
$0
$0
Ju
ly
Au
gu
st
Se
pt
em
be
r
Oc
to
be
r
No
ve
m
be
r
De
ce
m
be
r
Ja
nu
ar
y
Fe
br
ua
ry
M
ar
ch
Dollars (US)
$700
Community Service And Participation
MGSA has been very active in our community service efforts. MGSA won the 2012
MGSA Gives Back Award for the College of Graduate Studies. This year, MGSA
contributed 500 hours of community service through 29 service opportunities. Eight of
our members have at least 20 hours of service, and six of our members have over 40
hours of service! Table 1 displays community service hours for students that have
participated in MGSA service events.
2
2
2
2
2
3
6 2.5
3
3
6 2.5
3
3
3
6 2.5
3
3/19/2012
3/27/2012
3/28/2012
4/16/2012
5/26/2012
Tutoring
dinner at CYDC
CYDC Cookout
2/15/2012
CSU Career Day
3
CSU Visitation
2/3/2012
2
2/29/2012
1/25/2012
Go Red for Women
2
Tutoring
1/23/2012
Bake Sale
2
dessert at CYDC
1/18/2012
dessert at CYDC
2
E.E. Just Symposium2/24/2012
12/19/2011
Tutoring
6
2/20/2012
12/10/2011
dinner at CYDC
2
dinner at CYDC
12/1/2011
X-mas Basket
2
Party for a Purpose 2/23/2012
11/30/2011
Tutoring
World Aids Day
4
MLK Day of Service 2/18/2012
11/9/2011
10/27/2011
SFFF
2
11/14/2011
10/19/2011
Tutoring
2
dessert at CYDC
10/10/2011
dinner at CYDC
4
Spirit Night
9/6/2011
8/25/2011
Donut Fundraiser
Name
2
9/28/2011
8/22/2011
SURP Forum
TOTAL POSSIBLE HRS
Tutoring
7/13/2011
Event
Claflin Visit
Date
Donut Fundraiser
Table 1 MGSA Community Service Log
2
2 2.5
5
TOTAL
2
2
78
2
2
2.5
5
70
3
2
2
2
2 2.5
5
77
2
2
2
2 2.5
5
74
2.5
2.5
5
2
2
2
60
28
Email (@musc.edu)
Angela Alexander alexanaa
2
2
2
4
2
2
2
2
4
2
2
6
2
2
2
2
3
1
Denise Kimbrough kimbroug
2
2
2
4
2
2
2
2
4
2
2
6
2
2
2
2
3
1
2
2
4
2
2
2
2
4
2
2
6
2
2
2
2
3
2
2
2
2
2
4
4
2
2
2
2
1
4
2
2
2
4
2
2
2
2
2
1
3
2
2
2
4
2
2
2
6
2
2
2
1
2
2
4
2
2
2
Dorea Pleasant
pleasand
Jessica Ross
Sybil Nelson
rossj
princene
Nortorious Colemancolemann
Robert Bryant
bryantr
Fahmin Basher
basherf
Joy Buie
jonejn
Vondina Moseley
browv
Christy Cassarly
cassarly
2
2
Melanie Davis
davml
Danielle Clark
clarkdw
Jake Alsarraf
alsarraf
Christopher Smith smitcr
Danielle Brandon
brandond
Theresa Cantu
Kayla Hill
cantut
hillkr
2
2
4
3
3
6 2.5
3
3
6 2.5
2.5
3
3
6
3
3
2
2
2.5
5
41.5
2.5
5
43.5
0
2
2
4
2
3
2
2
2.5
2
2.5
22
3
5
2
4
2
4
4
3
1
2
3
2
1
16
0
2
2
1
5
2.5
5
3
1
7.5
3
7
6
Philip Sobolesky
sobolesk
6
6
Daniel Weinberg
weinber
6
6
David DeHart
dehart
Isaiah Davis
davisi
2
2
Daniel Odongo
odongo
2
2
Kristin Green
grekg
2
2
Jessica Silva
trombet
2
2
2
2
2.5
5
13.5
2
TOTAL HRS
501
42
Individual Accomplishments And Awards
Angela Alexander (MGSA President)
• MSAB VP Elect for 2012-2013
• MUSC Leadership Society nominee
• Attended Compact for Faculty Diversity's Institute on Teaching and Mentoring
(October 2011)
• Oral Presentation: Angela Alexander, Xuejun Wen. "Antimicrobial AllylamineGrafted Fibers for Treatment of Bacterial Wound Infections." 2012 World
Biomaterials Congress, Chengdu, China, June 2012.
• Poster Presentation: Angela Alexander, Xuejun Wen. "Antimicrobial AllylamineGrafted Fibers for Treatment of Wound Infections." MUSC Student Research
Day, Charleston, SC, November 2011.
Dorea Pleasant (MGSA Secretary, Elect, MGSA Career Devleopment Program
Chair)
• MGSA Vice President Elect for 2012-2013
• Poster Presentation: mTORC2-mediated Prosurvival Signaling Requires PKCε in
Adult Feline Cardiomyoctes, Department of Medicine Research Day
• T32 Cardiovascular Training Grant Recipient
Sybil Nelson (Historian)
• Poster Presentation: “Health Disparities in the Development of Lymphedema in
Breast Cancer Survivors.” Student Research Day, Charleston, SC 2011 – 1st
place winner Health Disparities
• Poster Presentation: “Health Disparities in the Development of Lymphedema in
Breast Cancer Survivors.” Hollings Cancer Research Day
• Poster Presentation: “Preliminary Steps for Developing a Lymphedema Risk
Assessment Tool.” Chalsty Cancer Research Retreat
• T32 Biostatistics Training Grant Recipient
Ludivine Renaud (Member At Large)
• Oral Presentation: Ludivine Renaud, Harinath Kasiganesan, Erhe Gao, Santhosh
Mani, Jeffrey Jones, Robert Stroud, Donald Menick. "Does Acetylation Regulate
miRNA Expression in Myocardial Infarction?" Student Research Day, Charleston,
SC, 2011. 1st place winner PhD V oral presentation category
• Poster Presentation: Ludivine Renaud, Harinath Kasiganesan, Erhe Gao,
Santhosh Mani, Jeffrey Jones, Robert Stroud, Donald Menick. "Does Acetylation
Regulate miRNA Expression in Myocardial Infarction?" Department of Medicine
Research Day, Charleston, SC, January 2012
Nortorious Coleman (Member-At-Large)
• MGSA President elect
43
Danielle Clark (Member At Large)
• MGSA Secretary elect
• Retreat at Riverland HOA Treasurer 2011, President 2012
Denise Kimbrough (Vice President)
• Reciepient of the 2012 AHA BCVS Cardiovascular Outreach Award
• MSAB Secretary elect
Goals And Challenges For 2012-2013
Goals:
 400 hours of community service
 Provide career development workshops
 Increase support from the school
 2 campus wide events including world aids awareness day
 Establish at least 1 high school outreach event
 Participate in MLK Service day and Sugar Free Fall Festival
 Increase MGSA's record and name on campus
 Continue outreach at CYDC and develop a homework help center with them
Challenges:
 Increasing participation of active members
 Gaining the support of departments in the grad school program
 Fundraising
44
Master of Science Clinical Research (MSCR)
Thomas C. Hulsey, MSPH, ScD
Student’s Name
Robert K. McCall
Owen Thornton Reeves
Barto Tara
Guille, Constance
Houston, Laura
Allen, Melissa
Athreya, Madhura
Barrett, Brandon
Baskaran, Amrutha
Bradshaw, Marques
Chakravarthi, Anusha
Chunduri, Anusha
Gadiko, Aditya reddy
Goodwin, Andrew
Hawk, Angela
Ikwuezunma, Gini
Jaiyeoba, Oluwatosin
McHugh, Kimberly
Morabito, Brianna
Nelluri, Vardhan Rao
Peng, Chunyan
Pisoni, Roberto
Rajab, Hussein
Singh, Abha
Soong, Bo
Tadimeti, Madhava
Tanner, Nichole
Williams, Daniel
Wu, Chang Long
Yu, Decai
Matriculation
Date
August 2008
August 2009
August 2010
August 2010
August 2010
August 2011
August 2011
August 2011
August 2011
August 2011
August 2011
August 2011
August 2011
August 2011
August 2011
August 2011
August 2011
August 2011
August 2011
August 2011
August 2011
August 2011
August 2011
August 2011
August 2011
August 2011
August 2011
August 2011
August 2011
August 2011
Mentor
Richard M. Silver
Ken Patrick
Patrick Flume
Thomas Uhde
Scott Sullivan
Kevin Delaney
Daniel Lackland
Daniel Lackland
Dianne Kamen
Leonie Gordon
Matthew Carpenter
Dianne Kamen
Matthew Carpenter
Gerard Silvestri
Christopher Robinson
Eric Rovner
D.E. Soper
A. Atz
Daniel Lackland
Daniel Lackland
Joseph Romagnoulo
Phillip Darwin Bell
Louis Luttrell
Dianne Kamen
Daniel Lackland
Daniel Lackland
Gerard Silvestri
William Basco
William Basco
Prabhakar Baliga
Degree
Sought
M. S. C. R.
M. S. C. R.
M. S. C. R.
M. S. C. R.
M. S. C. R.
M. S. C. R.
M. S. C. R.
M. S. C. R.
M. S. C. R.
M. S. C. R.
M. S. C. R.
M. S. C. R.
M. S. C. R.
M. S. C. R.
M. S. C. R.
M. S. C. R.
M. S. C. R.
M. S. C. R.
M. S. C. R.
M. S. C. R.
M. S. C. R.
M. S. C. R.
M. S. C. R.
M. S. C. R.
M. S. C. R.
M. S. C. R.
M. S. C. R.
M. S. C. R.
M. S. C. R.
M. S. C. R.
Students’ Publications, Journals, Abstracts, Presentations, Honors And Awards
Allen, Melissa
Honors
2010-2011 Provost Scholarship, 2010-2011
45
Bradshaw, Marques
Presentations
ML Bradshaw. “Basic PET/CT anatomy and pathology.” Presentation at the 2012 SNM
Midwinter Conference, Orlando Fl 26-30 January, 2012.
Goodwin, Andrew
Presentations
Clinical Trials in the ICU: Riding the Roller Coaster. Department of Medicine Grand
Rounds. Medical University of South Carolina. March, 2012.
Goodwin A, Zheng L, Lin L, Morse D. Small proline rich repeat protein 1a protects
against epithelial apoptosis and is a downstream target of Wnt proteins. Poster
presented at the American Thoracic Society International conference, Denver, CO,
USA, May 18, 2011.
Fernandez IE, Shi Y, Patel A, Goodwin A, Shi Y, Cernadas M, Morse D, Rosas IO.
Syndecan-2 ectopic expression promotes resistance to TGF-β induced apoptosis and
enhances malignant features in A549 cells. Poster presented at the American Thoracic
Society International conference, Denver, CO, USA, May 17, 2011.
Shi Y, Fernandez IE, Goodwin A, Patel A, Shi Y, Tang X, Yu G, Pacheco-Rodriguez G,
D’Armiento J, Morse D, Rosas IO. Alveolar macrophage Syndecan-2 transgenic mice
are protected from bleomycin induced lung fibrosis. Poster presented at the American
Thoracic Society International conference, Denver, CO, USA, May 18, 2011.
Journals
Goodwin A, et al. Sprr1a is a downstream target of the Wnt/β-catenin pathway and
protects against epithelial damage and mortality in a murine model of fibrosis (in
preparation).
Book
Goodwin A, Bajwa E, Malhotra, A. Minimally Invasive Hemodynamic Monitoring. Irwin
and Rippe’s Intensive Care Medicine (7th ed), Lippincott Williams & Wilkins, 2012.
Published
Goodwin, A.; Bajwa, E.; Malhotra, A. Minimally Invasive Hemodynamic Monitoring.
Procedures, Techniques, and Minimally Invasive Monitoring in Intensive Care Medicine
(5th Ed.). Lippincott, Williams & Wilkins, 2012. Published
Guille, Constance
Presentations
Guille, C., Rohrbaugh, R., Malison, B., Bunny S. Integrated, Mentored, Patient-Oriented
Research Training (IMPORT) in Psychiatric Residency Education: A Model for Meeting
a National Need. Austin, TX (March, 2011)
46
Poster
Grant, F., Guille, C., & Sen, S. Influence of major life stress on the relationship between
depression and subjective well-being. The Sixth World Conference on the Promotion of
Mental Health and Prevention of Mental and Behavioral Disorders. Washington, DC.
(2010).
Speller, H., Guille, C., Rubinstein, E., Rohrbaugh, R. Perspectives on Intern WellBeing: The Importance of Education, Support and Professional Satisfaction.
International Conference on Physician Health. Chicago, IL (Oct., 2010)
Guille, C., Grant F, Speller, H and Sen S. Depression in Medical Interns: Prevalence,
Predictors and Prevention. International Conference on Physician Health. Chicago, IL
(Oct., 2010)
Award
American Psychiatric Association, Research Colloquium for Junior Investigators, Travel
Award, 2010
Publications
Guille C, Clark S, Amstader A, Hawk A, Cartmell A, Sen S. Sex differences in
depression under conditions of chronic stress. Journal of Women's Health 2012; In
press.
Guille C & Sen S. Prescription Drug Use and Self-prescription Among Training
Physicians. Archives of Internal Medicine 2012; 172 (4): 371-372.
Sen S, Kranzler HK, Chan G, Speller H, Krystal JK, Gelernter J, Guille C. In Reply to
Kenneth S. Kendler, MD ‘The Stress of Internship and Interactions with Stress’.
Archives of General Psychiatry 2010; 67: 568-569
Sen S, Kranzler HK, Chan G, Speller H, Krystal JK, Gelernter J, Guille C. A Prospective
Cohort Study Investigating Factors Associated with Depression during Medical
Internship. Archives of General Psychiatry 2010; 67(6): 557-65. PMID: 20368500
Book Chapter
Guille C, Cortese B, Uhde T. Sleep in Anxiety Disorders, In: Therapy in Sleep Medicine,
Barkoukis TJ, Matheson JK, Ferber R, Doghramji K. (eds.), Saunders, an imprint of
Elsevier, Inc., 2012.
Resnick H, Guille C, McCauley J, Kilpatrick D. Rape and Other Sexual Assault, In:
Textbook on Resilience and Mental Health: Challenges Across the Lifespan, Southwick
SM, Litz BT, Charney D, Friedman (eds.), Cambridge University Press, New York,
2011.
47
Hawk, Angela
Publications
Hawk AF, Saller DN. Screening for fetal aneuploidy: is maternal age relevant? Clin
Obstet Gynecol 2012. 55 (1): 217-25.
Hawk AF, Pastore L, Saller DN. Genetic screening in a university clinic: impact of
primary language. Prenat Diagn 2011. doi: 10.1002/pd.2785.
Houston, Laura
Publications
Houston LE, Allsworth J, Macones GA, Ultrasound is safe…right?: resident and
Maternal-fetal medicine fellow knowledge regarding obstetric ultrasound safety.
Journal of Ultrasound in Medicine, 30 (1):21-7 (2011). Selected as CME test article and
online journal discussion.
Houston L, Tuuli M, Macones G, “Marfan syndrome and aortic dissection in
pregnancy”, Obstetrics and Gynecology, 117 (4): 956-60 (2011).
Houston L, Newman R, “Fetal ultrasound: how to put safety first”, Contemporary
Ob/Gyn, 56 (7): 36-42 (2011).
Houston L, Sullivan S. Marfan syndrome and vascular dissections during pregnancy.
Accepted to Minerva Ginecologica, 6/2012.
Houston L, Newman R. Management of labor and delivery: multiple gestations.
Accepted for publication in 2nd edition of Management of Labor and Delivery.
Presentations
Are serial ultrasound measurements following cerclage predictive. January 2011 of
preterm birth?”
Oral presentation, AAP section on Perinatal Pediatrics 35th
Southeastern conference on Perinatal Research
Placental expression of serotonin and norepinephrine transporters
across gestation” Poster presentation, 58th annual SGI conference , March 2011
Cesarean section: methods and evidence. Getting in” Medical University of South
Carolina, Ob Gyn Grand Rounds Sept 2011
Small incremental costs add up: are sterile gloves on labor and delivery justified?”
Poster presentation, 32nd annual SMFM conference, Feb 2012
Surgery for CIN and pregnancy outcome” Medical University of South Carolina, Fellows
conference. March 2012
Are serial ultrasound measurements following cerclage predictive of preterm birth?”
Poster presentation, 59th annual SGI conference. March 2012
48
Honors
2012
2011
2011
Teacher of the month nomination, January
ABOG board certification
Teacher of the month nomination, September
Ikwuezunma, Gini
Presentations
Gini Ikwuezunma BS, Andrew Colhoun BS, Robin Bhavsar MD, Samuel Deem DO and
Thomas Keane MD, Perineal prostatectomy remains a good option for obese and
overweight, Nov 2011, 1st Place Presentation at South Carolina Medical
Association
Early outcomes of urethral transection for dorsal or circumferential urethral diverticulumInvited to give Podium Presentation for CTSA National Predoctoral Conference- Mayo
Clinic –May 5, 2012
Honors
2012
Banov Humanitarian Award
Publications
Use of replication restricted recombinant vesicular stomatitis virus vectors for detection
of antigen-specific T cells. Journal. of Immuno Methods. 2012 Jan 31
Jaiyeoba, Oluwatosin
Publications
Jaiyeoba O, Amaya MI, Soper DE and Kilby JM. Preventing neonatal transmission of
herpes simplex virus. Clin Obstet Gynecol.2012 Jun; 55(2):510-520
Presentations
Jaiyeoba O, Kennedy E, Soper DE and Kilby JM. Epidemiology of women seeking HIV
care at Medical University of South Carolina. Poster presentation accepted for the 39TH
Annual Scientific Meeting of the Infectious Diseases Society for Obstetrics and
Gynecology 2012
Jaiyeoba O, Kohno S, Williams K and Soper DE. Epidemiology and clinical significance
of Mycoplasma genitalium in our gynecologic population: Preliminary Review. Poster
presentation accepted for the 39TH Annual Scientific Meeting of the Infectious Diseases
Society for Obstetrics and Gynecology 2012
Jaiyeoba O, Korte J, Villers M and Soper DE. Health Care Worker and Influenza
Vaccine. Poster presentation accepted for the 39TH Annual Scientific Meeting of the
Infectious Diseases Society for Obstetrics and Gynecology 2012
Jaiyeoba, O. Career in medicine for medical students. Obstetrics and Gynecology as a
career 2012
49
Jaiyeoba, O. Career in medicine for medical students. Obstetrics and Gynecology as a
career 2011
Honors
Panel member: South Carolina AHEC 2012
Medical University of South Carolina- Medical Education Innovation Committee 2011
Mentor: College of Graduate Studies- Summer health professional program 2011
McHugh, Kimberly E
Publications
Ledoux MR, Applegate SE, McHugh KE, Haizlip JA. Incidence of Intraventricular
Hemorrhage in Children with Coarctation of the Aorta. Supplement to the Critical Care
Medicine Journal. Volume 37, Issue 12. (doi: 10.1097/01.ccm.0000365439.11849.a2)
Gutgesell HP, Hillman DG, McHugh KE, Dean PN, Matherne GP. Use of an
Administrative Database to Determine Clinical Management and Outcomes in
Congenital Heart Surgery. World Journal for Pediatric and Congenital Heart Surgery.
Volume 2 Issue 4 October 2011 pp. 593 - 596.
Dean PN, Hillman DG, McHugh KE, Gutgesell HP. Inpatient Costs and Charges for
Surgical Treatment of Hypoplastic Left Heart Syndrome. Pediatrics. 2011; 128:5 e1181e1186 (doi: 10.1542/peds.2010-3742).
Honors
2011
2011
2011
2011
Invited Instructor, Medical University of SC College of Medicine ECG
Simulation Laboratory
Invited Speaker, Annual Horace G. Smithy Lectureship, MUSC Dept of
Cardiothoracic Surgery
MUSC Children’s Hospital Appreciative Inquiry Planning Committee,
Fellow Representative
Chief Fellow, Pediatric Cardiology, Medical University of South Carolina
Morabito, Brianna
Honors
2012
Student Leadership Society Nominee
Tripician Tanner, Nichole
Publications
Wang-Memoli J, El-Bayoumi E, Pastis NJ, Tanner NT, Huggins JT, et al. Using
endobronchial ultrasound features to predict lymph node metastasis in patients with
lung cancer. Chest. 2011; 140(6):1550-6.
50
Tanner NT, Watson P, Boylan A, Wang-Memoli J, Pastis N, Taylor K, Garrett-Mayer E,
Silvestri GA. Utilizing Endobronchial Ultrasound With Fine Needle Aspiration to Obtain
Tissue for Molecular Analysis: A Single Center Experience. J Bronchol Intervent
Pulmonol 2011;18:317–321
Tanner NT, Pastis NJ, Sherman C, Lewin D, Simon GS, Silvestri GA. The Role of
Molecular Analyses in the Era of Personalized Therapy for Advanced NSCLC. Lung
Cancer. 2011 Dec 14. [Epub ahead of print]
Tanner NT, Gomez M, Rainwater C, Neitert PJ, Simon GR, Green MR, Silvestri GA.
Physician Preferences for Management of Patients with Stage IIIA NSCLC: impact of
Bulk of Nodal Disease on Therapy Selection. J Thorac Oncol. 2012 Feb;7(2):365-9.
Tanner NT, Mehta H, Silvestri G. New Testing for Lung Cancer Screening. Oncology
2012. Feb 26(2).
Tanner NT, Pastis NJ, Silvestri GA. Training for Endobronchial Ultrasound among US
Pulmonary/Critical Care fellowships: A survey of fellowship directors. Accepted for
publication Chest 2012
Tanner NT, Sherman CA, and Silvestri GA. Biomarkers in the selection of maintenance
therapy in Non-small cell lung cancer. Accepted for publication Translational Lung
Cancer Research 2012.
Honors
2011
2011
Teacher of the month nomination
Chest Foundation Electronic Case of the Day- ACCP National Meeting
Pisoni, Roberto
Presentations
Nephrotoxic Drugs. 6th Annual Symposium on Management of Chronic Kidney
Diseases, Charleston, SC, March 5, 2011
Managing resistant hypertension and hypertension in chronic kidney disease. 7th
Annual Symposium on Management of Chronic Kidney Disease. Charleston, SC March
5, 2012.
Publications
Acelajado MC, Pisoni R, Dudenbostel T, Dell’italia LJ, Carmill F, Zhang B, Cofield SS,
Oparil S, Calhoun DA. Refractory hypertension: definition, prevalence, and patient
characteristics. J Clin Hypertens 14(1):7-12;12
Pisoni R, Acelajado MC, Cartmill fr, Dudenbostel T, Dell’italia LJ, Cofiel SS, Oparil S,
Calhoun DA. Long –term effects of aldosterone blockage in resistant hypertension
associated with chronic kidney disease.
J Hum Hypertens Jun 16.
doi:10.1038/jhh.2011.60, 2011 [Epub ahead of print]
51
Acelajado MD, Pisoni R, Dudenbostel T, Oparil S, Calhoun DA, Glasser SP. Both
morning and evening dose of nebivolol reduces rough mean blood pressure surge in
hypertensive patients. J Am Soc Hypertens 2011 Oct22 [Epub ahead of print]
Rajab, Hussein
Presentations
Rajab H ., Transient Diabetes Insipidus in Guillian Barre Syndrome. American
Association of Clinical Endicrinologist Meeting (2012)
Rajab H .,Spontaneous regression of pituitary macroadenoma after pituitary apoplexy.
American Association of Clinical Endrocrinologist Annual Meeting. (2011)
Wu, Chang
Presentations
Wu CL, Andrews AL, Teufel II, RJ, Basco Jr, WT. “Predictors of Leukotriene
Monotherapy Among Persistent Asthmatics.” Oral Presentation at 2012 Southern
Regional Meeting; 2012 February 9-11; New Orleans, LA.
Wu CL, Andrews AL, Teufel II, RJ, Basco Jr, WT. “Persistent Asthmatics at Risk to
Receive Leukotriene Modifier Monotherapy.” Poster Presentation at 2012 Pediatric
Hospital Medicine Conference; 2012 July 19-22; Northern
Kentucky
Williams, Daniel
Presentations
Predictors of Admission and Prolonged Length of Stay in Pediatric Skull Fractures.” Dan
Williams MD, Anbesaw Selassie DRPH, Scott Russell MD, William Basco MD MS;
Department of Pediatrics, Medical University of South Carolina. Southern Regional
Research Meeting 2012, New Orleans, LA
The Next Frontier in High-Fidelity Simulation: Long-Term Retention of Cognitive
Knowledge and Procedural Proficiency.” Dan Williams MD, Chang Wu MD, David Mills
MD, Joseph Dobson, MD; Department of Pediatrics, Medical University of South
Carolina. Pediatric Hospital Medicine Meeting 2011, Kansas City, MO
Honors
2012
Teacher of the month nomination
Program Accomplishments for 2011-2012
•
•
•
•
MSCR Website update in progress.
All MSCR Courses are now online.
Continued effort to align the MSCR Curriculum with the CTSA Core
Competencies
Working with Industry Course (MCR 789-07), Community Engaged Research
(MCR 789-04) added to curriculum.
52
•
•
•
•
•
•
•
•
•
•
•
•
Leadership (MCR 789-32) and Informatics/Data Management revised to address
competencies with the CTSA. As part of the revised Leadership Course – the
Invited Speaker Series included– Larry Olanoff, MD. PhD, Honorable Joseph P.
Riley, Charleston City Mayor, Dr. Ray Greenberg, MUSC President and John
Palms, PhD President Emeritus USC
Jordan Magarik, 2011 MSCR Graduate received the 2011 Student Scholarship in
Cerebrovascular Disease & Stroke- American Heart Association Stroke Council
Diane Kamen, MD, MSCR graduate- received the Developing Scholar Award at
the Faculty Convocation- August 2011
Constance Guille, MD and 2012 MSCR graduate successfully submitted a
BIRCWH application
Three Nanjing Drum Tower University students, Nanjing, China will complete the
program by end of summer 2012.
Seven MSCR/ICRI began the one-year program on the main campus and will
complete the degree by end of summer 2012.
Final two Predoctoral (deferred) MSCR students from CoP will complete the
program end of summer 2012.
Two CoM Predoctoral students are set to complete the MSCR by end of summer
2012.
Post doctoral students entering second-year program (2011-2013).
MSCR students and trainees poster presentations at the National Predoctoral
Meeting at the Mayo Clinic, Rochester, MN. May 6-8, 2012. Victor Fresco and
Gini Ikwuezunma selected to represent MUSC in oral presentation.
MSCR Graduate Accomplishment - Ziad Nahas, MD - from Adjunct Professor –
Dept. of Psychiatry to Professor and Chair of the American University of
Beirut/Dept of Psychiatry
MSCR Graduate Accomplishment - Frank Kozel- Director, Mood and Anxiety
Disorders Program and Associate Professor- Dept of Psychiatry and
Neurosciences University of South Florida (Tampa) Health
Program Goals for 2012-2013
•
•
•
•
•
•
•
Continue to align curriculum to meet the CTSA Core Competencies
MCR 789-04 Community Engaged Research developed for Summer 2012
MCR 789-07 Working with Industry developed for Summer 2012
Implement the CRAI Pre/Post survey for MSCR students to determine knowledge
and
Faculty retreat to discuss course evaluations and course compliance with CTSA
core competencies
Plans to offer the PhD Degree in Clinical Research
Increase enrollment at ICRI sites- 29 students have applied for the 2012-2013
term so far.
53
College of Medicine
MEDICAL SCIENTIST TRAINING PROGRAM
COMMITTEE
Steering Committee
2011-2012
Dr. Perry V. Halushka, Director
Professor of Pharmacology & Medicine
Dean, College of Graduate Studies
Dr. Robin Muise-Helmericks, Associate Director
Assistant Professor of Regenerative Medicine
and Cell Biology
Ms. Amy Connolly
Assistant Director, MSTP
Dr. John M. Arthur
Associate Professor of Medicine/Nephrology
Dr. Maria G. Buse
Professor of Medicine/Endocrinology
Dr. Michael Kern
Professor of Regenerative Medicine and Cell
Biology
Dr. Jim Oates
Associate Professor of Medicine
Dr. Shikhar Mehrotra
Assistant Professor of Surgery
Dr. Baerbel Rohrer
Professor of Neurosciences
Dr. Cyntha Schandl
Associate Professor of Pathology &
Laboratory Medicine
Dr. Rick Schnellmann
Professor & Chair of Pharmaceutical Sciences
Dr. Joann Sullivan
Assistant Dean for Extramural Program
Development
Dr. James A. Cook
Professor of Neurosciences
Dr. Deborah Deas
Senior Associate Dean for Medical Education,
College of Medicine
Professor, Psychiatry & Behavioral Medicine
Dr. Maurizio Del Poeta
Professor of Biochemistry & Molecular Biology
Dr. Scott Eblen
Assistant Professor of Cell & Molecular
Pharmacology
Dr. Stephen Tomlinson
Professor of Microbiology & Immunology
54
College of Medicine
COMMITTEES
2011-2012
Progress Committee
Dr. Perry Halushka
Dr. Robin Muise-Helmericks
Scholarship Committee
Dr. Perry Halushka
Recruitment Committee
Dr. Perry Halushka
Dr. Maria Buse
Dr. James Cook
Dr. Scott Eblen
Dr. Victoria Findlay
Dr. Elizabeth Garrett-Mayer
Dr. Michael Janech
Dr. Michael Kern
Dr. Yiannis Koutalos
Dr. Amanda LaRue
Dr. Shikrha Mehrotra
Dr. Carola Neumann
Dr. Jim Oates
Dr. Baerbel Rohrer
Dr. Cynthia Schandl
Dr. Ron See
Mr. Brandon Bentzley
Mr. Benjamin Newcomb
Mr. Lee Wheless
Mr. Ryan Whitaker
Dr. Cynthia Wright – Ex-officio
Dr. Deborah Deas – Ex-officio
Ms. Joan Graesch – Ex-officio
Seminar Committee
Mr. Joseph Cheng
Mr. Mohamad Dahrouj
Representative to Graduate Council
Mr. Anthony Leonard
55
College of Medicine
STUDENTS
MSTP
Matriculation
Students
Date
Advisor
Mohamad Adada
06/11 Dr. R. Young
Adnan Al-Ayoubi
8/05
Dr. S. Eblen
Joseph Alge
06/10 Dr. J. Arthur
Obaidallah Aseem
6/06
Dr. S. Argraves
DeAnna Baker
8/04
Dr. G. Gilkeson
Tiffany Baker
Fahmin Basher
Thomas Beckham
Brandon Bentzley
Jennifer Blakely
Jacob Bowers
Sarah Brice
Laura Briggs
Robert Cameron
Joseph Cheng
Danielle Clark
Mohammad Dahrouj
Anna-Maria De Costa
Andre Eaddy
Christopher Gault
George Russell Glenn
George Daniel Grass
David Hartmann
Linda Heffernan
Daniel Herr
Russell Jenkins
Christopher B Johnson
6/09
6/08
6/07
6/09
6/07
6/11
6/10
7/08
05/11
6/05
6/09
6/10
6/06
7/04
7/03
8/10
7/08
7/12
8/04
6/11
7/04
6/09
Craig Kutz
Anthony Leonard
Sarah Tucker Marrison
Ahmad Mashmoushi
Jamie Mills
Keely Morris
Khaled Moussawi
Thomas Mullen
Daniel Neitzke
Benjamin Newcomb
Ken Noguchi
Casey O’Dell
Armina Omole
6/10
1/07
6/08
7/07
6/11
6/06
8/05
6/03
6/10
6/09
5/12
6/10
7/05
Joseph Palatinus
6/05
Undergraduate School
American University of Beirut
Wofford University/MUSC
Morehouse College
University of Maryland-Baltimore
County
Dr. L. Cunningham
College of Charleston/MUSC
Dr. T. Nowling
University of South Carolina
Dr. J. Norris
Clemson University
Dr. G. Aston-Jones
College of New Jersey-Trenton
Dr. C. Beeson
Erskine College
Dr. T. Nowling
University of Utah
Dr. A. Cowart
Clemson University/MUSC
Dr. A. Wessels
University of Florida
Dr. C. Beeson
Davidson College
Dr. J. Norris
Dartmouth College
Drs. I. Singh/D. Jenkins Marshall University
Dr. C. Crosson
Dr. M. R. Young
Wofford University
Dr. R. Schnellmann
Morehouse College
Dr. L. Obeid
University of California-Santa Barbara
Dr. A. Tabesh
Wofford University
Dr. B. Toole
Charleston Southern University
Dr. L. J. Chandler
New College of Florida
Dr. L. Obeid
George Washington University
Dr. L. Obeid
University of Scranton
Dr. Y. Hannun
University of Virginia
Dr. D. Cole
University of North Carolina-Chapel
Hill
Dr. S. Kubalak
Minnesota State University Moorhead
Dr. B. Rohrer
Emory & Henry
Dr. J. Norris
Yale University
Dr. J. Oates
Dr. V. Findlay
California State University-Chico
Dr. S. Tomlinson
Cal Tech
Dr. P. Kalivas
Dr. L. Obeid
Clemson University
Dr. M. George
Dr. Y. Hannun
Seattle University
Dr. P. Howe
Kenyon College
Dr. N. Banik
Erskine University
Dr. P. Kalivas
University of Maryland Baltimore
County
Dr. R. Gourdie
Davidson College
56
David Perry
Saleh Rachidi
Ryan Rhome
Douglas Roberts-Wolfe
Sahar Saddoughi
Jennifer Scott
Achraf Shamseddine
Amena Smith
Joshua Smith
Adrian Sproul
Kyle Strickland
Erik Strungs
6/06
6/10
7/04
6/11
6/07
8/09
6/11
6/05
6/08
7/03
6/05
6/09
Alton Sutter
Peter Tang
Joseph Taylor
Abigail Washispack
Rebecca Weber
Lee Wheless
Ryan Whitaker
Katelyn Williams
6/07
6/06
6/07
6/12
6/08
6/05
6/08
6/12
Dr. Y. Hannun
Dr. Z. Li
Dr. M. Del Poeta
Dr. G. Aston-Jones
Dr. B. Ogretmen
Dr. G. Gilkeson
Dr. C. Voelkel-Johnson
Dr. N. Banik
Dr. N. Banik
Dr. P. D. Bell
Dr. S. Krupenko
Drs. R. Gourdie/
L. Luttrell
Dr. K. Chavin
Dr. R. Crouch
Dr. M. George
Dr. J. Jones
Dr. M. Wargovich
Dr. A. Alberg
Dr. R. Schnellmann
Dr. B. Ogretmen
Parker C. Wilson
Xiaoyi Zhang
6/05
6/08
Drs. L. Luttrell
Dr. K. Kirkwood
57
Clemson University
University of Georgia
Hampshire College
Barnard College
University of Central Florida
Lee College
Wofford College
Oberlin College
University of Minnesota-Twin Cities
University of Pennsylvania
Davidson College
University of Arkansas Ft. Smith
Denison University
Davidson College
University of Iowa
University of Maryland Baltimore
County
Johns Hopkins University
MSTP Graduates (1982-2011)
MSTP Graduate
Date
Residency
Samuel E. Gandy, III, MD,
PhD
1982
Cornell
University
Geoffrey E. Renk, MD,
PhD
Robert P. Aftring, MD, PhD
1986
UCLA
1987
Beth Israel
Charles F. Burant, MD,
PhD
1987
University of
California San
Francisco
Kevin D. Ballard, MD, PhD* 1989
Baylor College of
Medicine
Richard L. Griffith, MD,
PhD
Stanley A. Katz, MD, PhD
1989
Margaret O. Sowell, MD,
PhD
1990
Richard H. Peters, MD,
PhD
N. Carolyn Schanen, MD,
PhD
1991
University of
Virginia Hospital
Vanderbilt
University
Brigham and
Women's
Hospital
Massachusetts
General Hospital
Stanford
University
Keith A. Coffee, MD, PhD
1992
Vanderbilt
University
Stephen R. Murray, MD,
PhD
1992
Jeffery L. Twiss, MD, PhD
1992
University of
California San
Francisco
Stanford
University
William Oehlenschlager,
MD, PhD
1993
1989
1991
Case Western
Reserve
University
58
Current Position
Mt. Sinai Professor Alzheimer’s
Research, Professor of Neurology
& Psychiatry. Mt. Sinai Medical
School
Emergency Medicine, Mt. Pleasant,
SC
Group Director, Clinical
Cardiovascular and Metabolic
Medicine Development Center,
Glaxo-Smith Kline and French
Professor of Medicine, Professor of
Molecular Integrative Physiology,
Robert C. & Veronica Atkins
Professor of Metabolism, University
of Michigan
Director of Research and
Development, National Medical
Services Labs, Willow Grove PA
Practice in Internal
Medicine/Immunology, Marietta, GA
unknown
Global Clinical Safety and
Pharmacovigilance,
GlaxoSmithKline
Vice President, Head of Global
Medical Affairs, Sanofi Oncology
Adjunct Associate Professor,
Biological Sciences, University of
Delaware/Head, Human Genetics
Research, A.I. duPont Hospital for
Children
Senior Medical Director, Global
Therapeutic Development,
Pharmaceutical Product
Development, Inc.
Senior Medical Officer, TB Alliance,
New York, NY
Professor & Department Head,
Department of Biology, Drexel
University
WRH Health System, Wadsworth
OH
C. Richard Ross, MD, PhD
1993
Kendrick A. Shunk, MD,
PhD
1993
Charles J. Beischel, MD,
PhD
1994
J. Bryan Hill, MD, PhD
1995
Charles T. Ivester, MD,
PhD
1996
University of
Utah
Timothy C. Ball, MD, PhD
1997
Bowman Gray
Bradley S. Miller, MD, PhD
1997
Mayo Clinic
Kimberly V. Barnes, MD,
PhD
Gloria J. Bullock Morris,
MD, PhD
1998
1998
University of
Chicago
Thomas
Jefferson
University
Charles E. Hill, MD, PhD
1998
Emory University
Ana Maria Ibrado, MD,
PhD
1998
Johns Hopkins
University
John H. Cleator, MD, PhD
1999
Cleveland Clinic
Michel A. Makhlouf, MD,
PhD
1999
Cynthia A. Schandl, MD,
PhD
Keith T. Borg, MD, PhD
1999
University of
Pittsburgh
Magee Women's
Hospital
Medical Univ. of
South Carolina
University of
Cincinnati
2000
Johns Hopkins
University
University of
Chicago
Medical
University of
South Carolina
Baylor University
59
Practice in Emergency Medicine,
Modesto, CA
Associate Professor of Medicine,
Director Cardiac Catheter Lab,
UCSF
Clinical Assistant Professor of
Ophthalmology, MUSC
Private Practice, Anderson SC
Practice in Internal Medicine,
Pulmonary Medicine, Salt Lake
City, UT
Assistant Professor, Internal
Medicine, Virginia Tech Carilion
School of Medicine/Interventional
Cardiologist, Carilion Clinic,
Roanoke, VA
Associate Professor of Pediatrics,
Division of Pediatric Endocrinology,
University of Minnesota
Private Practice, Chicago IL
Assistant Professor of Medicine,
Department of Oncology, Mt. Sinai
School of Medicine, Tisch Cancer
Institute
Assistant Professor of Pathology &
Laboratory Medicine, Director
Molecular Diagnosis, Emory
University
Practice in Emergency Medicine
Providence Hospital, Washington,
DC
Cardiology Division
Director of the Experimental
Angiographic Laboratory, Vanderbilt
University
Assistant Professor, OB/GYN,
University of Texas, Galveston
Associate Professor, Department of
Pathology, MUSC
Associate Professor, Emergency
Medicine/Division Chief, Pediatric
Emergency, MUSC
Justin P. Favaro, MD, PhD
2000
Kim M. Huffman, MD, PhD
2000
Antoine A. Makhlouf, MD,
PhD
Donald C. Shields, MD,
PhD
2000
Kristie B. Blade, MD, PhD
2001
Mark (Horney) Jameson,
MD, PhD
2001
Chad E. Hudson, MD, PhD
2001
Deanne L. King, MD, PhD
2002
2000
Richard A. Walgren, MD,
2002
PhD
Joseph R. Kelley, MD, PhD 2003
Stewart M. Knoepp, MD,
PhD
2003
Bryce A. Nelson, MD, PhD
2003
Christopher D. Willey, MD,
PhD
2003
Scott P. Commins, MD,
PhD
2004
Christopher A. Wells, MD,
PhD
Ralph J. Barker, MD, PhD
2004
Kevin Becker, MD, PhD
2005
2005
University of
Texas, Dallas
Southwestern
Medical Center
Duke University
University of
Virginia
UCLA
University of
Washington
University of
Virginia
University of
Maryland
University of
Arkansas
Washington
University
Medical College
of Virginia
Massachusetts
General
Hospital/Harvard
Vanderbilt
University
Vanderbilt
University
Assistant Consulting Professor,
Department of Medicine, Duke
University/Private Practice
Hematology Oncology
Division of Rheumatology, Duke
University Medical Center
Staff Physician, Physical Medicine
& Rehabilitation, Durham VA
Medical Center
Private Practice, Urology, Sugar
Land, TX
Assistant Professor of
Neurosurgery, George Washington
Virginia Mason Medical Center (last
known position)
Assistant Professor of
Otolaryngology, University of
Virginia
Private Practice OB/GYN,
Hagerstown, MD
Resident in Otolaryngology,
University of Arkansas
Senior Medical Advisor for
Oncology, Eli Lilly, Indianapolis, IN
Private Practice in Radiation
Oncology, Wichita, Kansas
Assistant Professor of Pathology,
University of Michigan
Pediatric Endocrinology, Greenville,
SC
Assistant Professor of Radiation
Oncology, Univ. of Alabama,
Birmingham
University of
Virginia
Asthma & Allergic Diseases Center,
Vanderbilt
Research Instructor, Cardiovascular
University
Medicine, Vanderbilt University
MUSC
2005
MUSC/Surgery
SurgicalResident
Critical Care Fellowship,
MUSC
Yale
Assistant Professor, Neurology,
Division of Medical Neuro-oncology,
Yale University
60
Michael L. Bernard, MD,
2005
PhD
Christopher V. Crosby, MD, 2005
PhD
Lena Heung, MD, PhD
2007
Shantae Jenkins, MD, PhD
2007
Vanderbilt
Fellow, Electrophysiology
University
2005
Vanderbilt
Cardiology,
University/Internal
MUSC Medicine Resident
Emory University Clinical Assistant Professor,
Dermatology, University of
California San Diego
Emory University Clinical Assistant Professor,
Ophthalmology, University of
California San Diego
Cleveland Clinic Assistant Professor, Dermatology,
Emory University
University of
Asheville Radiology, Asheville, NC
Virginia
Washington
Private Practice, Radiology,
University, St.
Yorktown, VA
Louis
Duke University
Cardiology, St. Francis Medical
Group, Indianapolis, IN
Emory University Assistant Professor, Preventive
Medicine, University of AlabamaBirmingham
University of
Infolded Fellowship in
Chicago
Cerebrovascular and Skull Base
Surgery, University of Chicago
Johns Hopkins
Fellow, Endoscopic Sinus & Skull
Base Surgery, Stanford University
MD Anderson
Assistant Professor, Radiation
Oncology, University of Texas
Southwestern
UCSD
Maternal/Fetal Medicine Fellow,
University of Utah Health Sciences
Baystate/Tufts
Fellow, Infectious Diseases,
Affiliate
University of Washington
MUSC
Hospitalist, Colleton Medical Center
Eric Sribnick, MD, PhD
2007
Emory University
Tarek Taha, MD, PhD
2007
David Arrington, MD, PhD
2008
Mary Lee Gregory, MD,
PhD
2008
Indiana
University
Georgetown
University/MUSC
Baystate/Tufts
Affiliate
Gregor Krings, MD, PhD
2008
John Shea, MD, PhD
2008
Michelle B. Crosby, MD,
PhD
2005
Ron J. Feldman, MD, PhD
2005
Joshua M. Hubbard, MD,
PhD
Benjamin J. Pettus, MD,
PhD
2005
Vijay U. Rao, MD, PhD
2005
Nicole Redmond, MD, PhD
2005
Stephen F. Shafizadeh,
MD, PhD
2005
Justin Turner, MD, PhD
2006
John Yordy, MD, PhD
2006
2005
Zachary Bowman MD, PhD 2007
Mass. General
Hospital/UCSF
Allegheny
General
61
Resident, Neurosurgery, Emory
University
Fellow, Orthopedic Trauma
Surgery, Scottsdale, Arizona
Fellow, Body Imaging, University of
Alabama Birmingham
Resident, Pediatric Neurology and
Neurodevelopmental Medicine,
Johns Hopkins Kennedy-Krieger
Institute
Research Fellow, Pathology, UCSF
Resident, Emergency Medicine,
Allegheny General
Laura Spruill, MD, PhD
2008
MUSC
Fellow, Surgical Pathology, MUSC
Brice Williams, MD, PhD
2008
Saeed ElOjeimy, MD, PhD
2009
Amanda Galloway, MD,
PhD
2009
Resident Ophthalmology, University
of Utah
Resident, Diagnostic Radiology,
Resident, Pediatrics, University of
Texas-Southwestern
Jason Guichard, MD, PhD
2009
University of
Utah
University of
Washington
University of
Texas
SouthwesternDallas
University of
AlabamaBirmingham
Mark Hallman, MD, PhD
2009
Youssef Zeidan, MD, PhD
2009
Rany Abdallah, MD, PhD
2010
Jamie Fraser, MD, PhD
2010
Mona Taleb, MD, PhD
2010
Juan Varela, MD, PhD
2010
Jonathan Butler, MD, PhD
2011
MUSC/Fox
Chase Cancer
Center
Stanford
University
MUSC/
Lenox Hill/Rush
National
Institutes of
Health
Mt. Sinai Medical
Center-Miami/
Wayne State
Johns Hopkins
University
Vanderbilt
Justin Ellett, MD, PhD
2011
MUSC
Loretta Jophlin, MD, PhD
2011
Mt. Sinai
Jason Lockrow, MD, PhD
2011
University of
Washington
University of
Cincinnati
MUSC/VCU
Phillip Moschella, MD, PhD 2011
Michael O’Quinn, MD, PhD
2011
Brian Snarr, MD, PhD
2011
Jarrett Walsh, MD, PhD
2011
Adnan Al-Ayoubi, MD, PhD 2012
University of
TexasSouthwestern
University of
Iowa
MUSC
DeAnna Baker, MD, PhD
Duke
2012
Resident, American Board of
Internal Medicine Research
Pathway, University of Alabama
Birmingham
Resident, Radiation Oncology, Fox
Chase Cancer Center
Resident, Radiation Oncology,
Stanford
Resident, Anesthesiology, Rush
Resident, Pediatric Genetics
Resident, Surgery, Wayne State
Resident, Internal Medicine, Johns
Hopkins University
Resident, Adult Neurology,
Vanderbilt
Resident, Surgery/Urology, MUSC
Resident, Internal Medicine, Mt.
Sinai
Resident, Pediatric Neurology,
Resident, Emergency Medicine,
University of Cincinnati
Resident, Internal Medicine,
Virginia Commonwealth University
Resident, Pediatrics, University of
Texas-Southwestern
Resident, Otolaryngology,
University of Iowa
Intern, General Surgery, MUSC
Resident, Internal Medicine, Duke
University
62
Christopher Gault, MD,
PhD
Linda Heffernan-Stroud,
MD, PhD
2012
Russell Jenkins, MD, PhD
2012
Mass General
Khaled Moussawi, MD,
PhD
Thomas Mullen, MD, PhD
2012
Mass General
2012
Tufts/University
of Washington
Ryan Rhome, MD, PhD
2012
MUSC/Mt. Sinai
Adrian Sproul, MD, PhD
2012
MUSC/UNC
Chapel Hill
2012
University of
Pennsylvania
Eastern Virginia
Medical Center
*Deceased
63
Resident, Pathology, University of
Pennsylvania
Intern, Internal Medicine Greenville
Memorial/Resident, Dermatology,
Eastern Virginia Medical Center
Intern, Internal Medicine,
Massachusetts General Hospital
Intern, Internal Medicine/Resident,
Neurology, Brigham & Women’s
Intern, Lemuel Shattuck
Hospital/Resident, Radiation
Oncology, University of Washington
Intern, Internal Medicine,
MUSC/Resident, Radiation
Oncology, Mt. Sinai Hospital
Intern, Transitional Surgery, MUSC/
Resident, Anesthesia, UNC Chapel
Hill
HIGHLIGHTS (2011-2012)
The national prominence of the program continues to increase significantly. This year,
we had 174 applications, the highest number in the history of the program. Last year we
had 164 applications. The quality of the applicant pool remains very high. We
interviewed a total of 55 applicants. The average GPA and MCAT scores of the
interviewees were 3.75 and 33.84, respectively. We had a total of 4 new students
matriculate. Their GPA and MCAT scores were 3.76 and 34.25, respectively. Of
particular note, is the extensive undergraduate research experiences that the applicants
had. It was clear during the recruitment process that we continue to compete with the
best programs in the country.
David Hartmann and Abigail Washispack, incoming first year students, were both
awarded the annual MUSC Physicians/MSTP scholarship. David Hartmann was also
awarded the Lane scholarship and the Suzann Pershing Award. Anna-Maria De Costa
was awarded an SCE&G scholarship. From the Hollings Cancer Center, Daniel Neitzke
and Katelyn Williams received the Abney scholarship. The seven students who were
awarded NIH predoctoral fellowships from the training grant are Robert Cameron,
Joseph Cheng, G. Daniel Grass, Daniel Herr, Jamie Mills, Ken Noguchi and Lee
Wheless.
Congratulations to Sarah Brice Russo and Joe Taylor who received Ruth Kirschstein
NSRA fellowships. Our success rate for obtaining these NRSA fellowships is
approximately twice the national average, which is 30%.
Our new students and their undergraduate institutions are listed below.
David Hartmann
New College of Florida
Ken Noguchi
Kenyon College
Abigail Washispack
University of Arkansas Fort Smith
Katelyn Williams
University of Maryland Baltimore County
This year we graduated nine students.
Institution
Adnan Al-Ayoubi
MUSC
DeAnna Baker
Duke University
Chris Gault
University of Pennsylvania
Linda Heffernan-Stroud Greenville Memorial
Eastern Virginia Medical Ctr
Russ Jenkins
Massachusetts General
Khaled Moussawi
Massachusetts General
Brigham & Women’s
Tom Mullen
Lemuel Shattuck Hospital
Ryan Rhome
MUSC
Mt. Sinai
Adrian Sproul
MUSC
64
Field of Study
General Surgery
Internal Medicine
Pathology
Internal Medicine
Dermatology
Internal Medicine
Internal Medicine
Neurology
Transitional Year
Radiation Oncology
Internal Medicine
Radiation Oncology
Transitional Surgery
UNC-Chapel Hill
Anesthesia
Russell Jenkins and Khaled Moussawi were named as co-recipients of the
Distinguished Graduate of the Year Award. This was unprecedented as the Award
Committee deemed both students’ accomplishments outstanding and could not
distinguish between them. They will both return in August to present the Liz Chesterman
Memorial lecture to the incoming graduate students.
The monthly student seminar series, which are organized by the students, continues to
be very successful. It is scheduled for the fourth Monday of each month at 5:00 p.m.
Faculty from our institution presented informal research seminars at each of the
meetings. These interactions have resulted in several students choosing the presenters
as mentors for research projects. This year, three students who were ready to defend
their dissertation presented their research. This provided an excellent venue for them to
practice their presentation. It also allowed the other students in the program to learn
about their colleague’s research.
10/10/11
Kyle Strickland
2/27/12
Sahar Saddoughi
5/21/12
G. Daniel Grass
Our Translational Medicine Seminar series has been a great success. Each one of our
senior students paired with one of our faculty to present a clinical case. This was
followed by a research discussion by the faculty member focused on the disease that
was presented. The topics and speakers are listed below:
7/11/11
DeAnna Baker with Gary Gilkeson, MD
Advances in the Systemic Lupus Erythematosus
8/8/11
Russell Jenkins with John Lazarchick, MD and Keisuke Shirai, MD
Hemophagocytic Lymphohistiocytosis: A Rare, but Often Fatal NonMalignant Systemic Inflammatory Condition - Case Review, Diagnosis,
Treatment, and Current Investigations
9/26/11
Chris Gault with Milos Budisavljevic, MD
TTP And Plasma Exchange; From Clinic To Bench And Back To Clinic
1/9/12
Adrian Sproul with Francis McGowan, MD
Single Ventricle Physiology In Adults Following Staged Repair Of
Congenital Heart Disease
2/13/12
Linda Heffernan-Stroud with Keith Borg, MD, PhD
Traumatic Brain Injury - Challenges in Translation
3/12/12
Khaled Moussawi with Leonardo Bonilha, MD, PhD
The Quest for Understanding Epilepsy Through Neuroimaging
4/9/12
Ryan Rhome with Ernest Camp, MD, MSCR
Targeting EMT to Enhance Therapy of Colon Cancer
The Translational Sciences Clinics have proven to be a very rewarding and successful
experience for our students. Both the students and faculty have provided very positive
evaluations.
65
During this past year eleven students; Joseph Cheng, Anna-Maria De Costa, Andre
Eaddy, G. Daniel Grass, Joseph Palatinus, David Perry, Sahar Saddoughi, Amena
Smith, Kyle Strickland, Lee Wheless and Parker Wilson successfully defended their
Ph.D. dissertations.
Our 22nd Annual MSTP Student Research Day was held on March 24, 2012 in the
Bioengineering Building. There were 10 oral, 27 poster presentations as well as 4
Clinical and Translational Research Center presentations. All of the presentations
reflected the high quality science that our students are conducting. One of our alumni,
Scott Commins, M.D., Ph.D., Assistant Professor of Medicine and Pediatrics at the
University of Virginia, was the keynote speaker. The title of his talk was “Delayed
Anaphylaxis to Mammalian Meat: How Oncologists Helped Discover a Novel Food
Allergy.”
This has also been an exciting year for many of our students. Jennifer Blakeley became
engaged to Joey Harmon, Danielle Clark became engaged to Charlie Lowe and Alton
Sutter became engaged to Alina Ovechkina, Anthony Leonard and Emily Bowen were
married in October, Erik Strungs and Amanda Zimmerman were married in November,
Andre Eaddy and Nicole Rogers were married in May and Sarah Brice and Adam
Russo were also married in May. Joey and Mikah Alge had a baby girl, Eleanor, on
March 2 and Anna-Maria and Brian De Costa had a baby boy, Benjamin, on June 8.
Sarah Brice & Adam Russo
(and Ben)
Andre Eaddy & Nicole Rogers
(Deontae, Myles and Madison)
66
Casey O’Dell & Joshua Holmes
Anthony Leonard & Emily Bowen
Erik Strungs & Amanda Zimmerman
Eleanor Lynn Alge
Benjamin Augustus De Costa
67
Our students continue to garner many honors and awards that you will see listed after
their names. Including the incoming class, we currently have 53 students in the
program.
GOALS FOR 2012-2013
•
•
•
•
•
We will continue to try to identify philanthropic support for the program
We will re-evaluate our recruitment and admissions process
Increase the size and quality of our applicant pool
Formally evaluate the program via the instrument developed at the time of the
submission of the grant
Replace the program director
68
AWARDS AND HONORS (2011-2012)
Listed below are the many honors and awards our students have garnered during the
past year.
Student’s Name (Year of Matriculation)
Joseph Alge (2010)
American Society of Nephrology 2011 Kidney Week Travel Award
2011
Tiffany Baker (2009)
Ruth L. Kirchstein National Research Service Award F30
2011
Fahmin Basher (2008)
Travel Award American College of Rheumatology Research Workshop
2012
Thomas Beckham (2007)
MUSC College of Medicine’s Most Outstanding Student Volunteer
2012
Brandon Bentzley (2009)
NIH/MSTP Predoctoral Fellowship Training Grant, GM08716
American Society for Clinical Pathology Award for Academic Excellence
and Achievement
2011-2012
Jennifer Blakely (2007)
Ruth L. Kirchstein National Research Service Award F30 DK091107
2011-2012
Jacob Bowers (2011)
Desiree Roy Research Scholarship
2012
2011-2012
Laura Briggs (2008)
Travel Award to 2012 Weinstein Conference
Robert Cameron (2011)
Lane Family Scholarship
University Medical Associates/MSTP Scholar
Mohammad Dahrouj (2010)
Travel Award ARVO Foundation/Retina Research Foundation/Joseph M.
and Eula C. Lawrence
Danielle Desjardins (2011)
SCTR TL1 Trainee
2011-2012
2012
2011
2011-2012
2012
2011-2012
69
Chris Gault (2003)
Ruth L. Kirchstein National Research Service Award F30 HL093991-01A1 2011-2012
George Russell Glenn (2010)
2011-2012
George Daniel Grass (2008)
Travel Award for ASCI (American Society for Clinical Investigation), AAP
(Association of American Physicians) Joint Meeting
2012
Regulation of Invadopodia Formation and Activity by CD147. J Cell Science;
125(Part3): 777-788, 2012. Paper was reviewed by a member of the
faculty of 100 which places the work in a library of the top 2% of published
articles in biology and medicine
2012
1st Place, PhD Poster III Category, The Perry V. Halushka MUSC Student
Research Day
2011
DOD Breast Cancer Research Program Predoctoral Traineeship
W81XWH-10-1-0083
2011-2012
Presidential Scholar
2011-2012
Linda Heffernan-Stroud (2004)
Ruth L. Kirschstein National Research Service Award, F30ES017379
2011-2012
Daniel Herr (2011)
University Medical Associates/MSTP Scholar
2011-2012
Casey O’Dell Holmes (2010)
2011-2012
Russell Jenkins (2004)
South Carolina Electric & Gas Scholarship
2011-2012
MUSC College of Graduate Studies Distinguished Graduate Student Award
2012
Christopher Bryce Johnson (2009)
MUSC Hollings Cancer Center Abney Foundation Scholarship
2011-2012
Anthony Leonard (2008)
Travel Award, 26th Annual National MD/PhD Student Conference
2011
Jamie Mills (2010)
Lane Family Scholarship
2011
Keely Morris (2006)
Ruth L. Kirchstein National Research Service Award F30 DK089696-01
70
2011-2012
Khaled Moussawi (2005)
Alpha Omega Alpha Medical Society
MUSC College of Graduate Studies Distinguished Graduate Student Award
2011
2012
Thomas Mullen (2003)
Ruth L. Kirchstein National Research Service Award F30
2011-2012
Alpha Omega Alpha Medical Society
2011
MUSC College of Graduate Studies Distinguished Graduate Student
Finalist
2012
Daniel Neitzke (2010)
2011-2012
Benjamin Newcomb (2009)
MUSC Hollings Cancer Center Abney Foundation Scholarship
2011-2012
Joseph Palatinus (2005)
Ruth L. Kirschstein National Research Service Award, 1F30HL095320-01 2011-2012
Saleh Rachidi (2010)
Award from South Carolina Clinical and Translational Research Institute
(SCTR) for inflammatory genes in cancer
2012
Ryan Rhome (2004)
MUSC Student Leadership Award
2012
Douglas Roberts-Wolfe (2011)
Suzann Pershing Scholarship
2011-2012
2011-2012
Sarah Brice Russo (2010)
Ralph H. Johnson VAMC Student Research Honorable Mention Certificate,
PhD Oral VI Category, The Perry V. Halushka MUSC Student Research
Day
2011
Ruth L. Kirchstein National Research Service Award F30 DK09125
2011-2012
Presidential Scholar
2011-2012
Sahar Saddoughi (2006)
Ruth L. Kirschstein National Research Service Award, F30
2011-2012
Amena Smith (2005)
Ruth L. Kirschstein National Research service Award F31EY019457-01
2011-2012
Joshua Smith (2008)
2nd Place, PhD Oral VI Category, The Perry V. Halushka MUSC Student
Research Day
71
2011
Kyle Strickland (2005)
Sigma Xi Award, MUSC Student Research Day
2011
2nd Place, Ph.D. Oral VII Category, The Perry V. Halushka MUSC Student
Research Day
2011
Ruth L. Kirschstein National Research Service Award 1F30DK08321501A2
2011-2012
Erik Strungs (2009)
SCTR TL1 Trainee
2011-2012
Peter Tang (2006)
1st place, Clinical-Professional-Masters Oral VI Category, The Perry V.
Halushka MUSC Student Research Day
2011
2011-2012
Joseph Taylor (2007)
Student Research Honorable Mention, Ralph H. Johnson VAMC
Women’s Club Scholarship, Medical University of South Carolina
Howard Hughes Medical Institute Teacher Training Fellowship, College of
Charleston
MUSC, College of Graduate Studies Most Outstanding Student Volunteer
Selected for NINDS/AUPN Combining Clinical/Research Careers in
Neuroscience Symposium
1st Place Poster Presentation, 13th Annual Frontiers in Neuroscience
Research Day
NIDA NRSA F30 Fellowship Award, National Institutes of Health, NIDA
1F30DA033748-01
Penn Fellowship in Neuroscience & Society, University of Pennsylvania
American Neuropsychiatric Association (ANPA) Young Investigator Award
2011
2011
2011
2012
2012
2012
2012
2012
2012
Lee Wheless (2005)
Society for Investigative Dermatology PhD Retreat Invited Attendee
2012
Xiaoyi Tina Zhang (2008)
2nd place, PhD IV Oral Category, The Perry V. Halushka MUSC Student
Research Day
American Medical Association Foundation Seed Grant Recipient
2011
2012
72
PUBLICATIONS
Our students have also been very productive in their research endeavors, as witnessed
by their publication records. In 2011-2012 they authored or co-authored 60 manuscripts
that have been published or are in press and an additional 15 manuscripts have been
submitted. Three book chapters have been published and 2 in preparation (compared
to 1 last year) and they submitted 110 abstracts for presentation compared to 102 last
year.
MSTP Publications
80
70
60
50
40
30
20
10
0
Submitted
Published/
In Press
2004- 2005- 2006- 2007- 2008- 2009- 2010- 201105
06
07
08
09
10
11
12
Adnan Al-Ayoubi (2005)
Abstracts:
Al-Ayoubi AM, Zheng H, Liu Y, Bai T, Eblen ST. ERK2 Phosphorylation of Splicing
Factor 45 (SPF45) Regulates SPF45 Alternative Splicing Site Utilization and
Downstream Gene Expression. The Perry V. Halushka MUSC Student Research Day.
Charleston, SC. November 2011
Liu Y, Al-Ayoubi A, Zheng H, Bethard J, Eblen ST. The SR Protein Kinase Clk1
Phosphorylates SPF45 and Regulates Its Degradation and Splice-Site Selectivity. The
Perry V. Halushka MUSC Student Research Day. Charleston, SC. November 2011
73
Joseph Alge (2010)
Abstracts:
Alge J, Chawla LS, Tumlin JA, Arthur JM. The Ratio of alpha-1-Acid Glycoprotein to
alpha-1B Glycoprotein in Urine Is an Early and Accurate Predictor of Acute Kidney
Injury [Abstract]. J Am Soc Nephrol 22, 2011: 358A.
Alge JL, Janech MG, Shaw AD, Chawla LS, Tumlin JA, Arthur JM. The Ratio of Alpha1B-Glycoprotein to Zinc Alpha-2 Glycoprotein in Urine Is an Early and Accurate
Predictor of Acute Kidney Injury. The Perry V. Halushka MUSC Student Research Day.
Alge JL Janech MG, Shaw AD, Chawla LS, Tumlin JA, Arthur JM. Urinary
Angiotensinogen Predicts Acute Kidney Injury After Cardiac Surgery. MUSC MSTP
Research Day, Charleston, SC, March 24, 2012
Obaidullah Aseem (2006)
Abstracts:
Aseem O, Smith BT, Cooley MA, Argraves WS. Cubilin is Essential for Maintaining
Blood HDL Levels, The Perry V. Halushka MUSC Student Research Day. Charleston,
SC. November 2011
Aseem O, Smith BT, Cooley MA, Argraves WS. The Epigenetic Regulation of MultiLigand Receptor Cubilin. MUSC MSTP Research Day, Charleston, SC, March 24, 2012
DeAnna Baker (2004)
Manuscripts:
Baker, DA, Obeid LM, Gilkeson GS. Impact of sphingosine kinase on inflammatory
pathways in fibroblast-like synoviocytes. Inflamm Allergy Drug Targets. 2011 Dec
1;10(6):464-71
Abstracts:
Hunter DA, Baker DA, Gray J, Gonsalves W. Point of Care Testing for Diabetic Patients
in the Student Run Free Clinic: Advantages for the Patients, Students, and Your Bottom
Line. Society for Student Run Free Clinics Annual Meeting, Houston, TX January 2011
Tiffany Baker (2009)
Manuscripts:
Bullard SA, Baker T, de Buron I. New species of Cardicola (Digenea: Aporocotylidae)
from heart of Atlantic Croaker, Micropogonias undulatus (Perciformes: Sciaenidae), of
the South Atlantic Bight. Journal of Parasitology 98(2):328-332
Fahmin Basher (2008)
Abstract:
Basher F, Amani A, Bunni M, Nowling T. Effects of Fli1 on T Cell Function in Systemic
Lupus Erythematosus. MUSC MSTP Research Day, Charleston, SC, March 24, 2012
74
Thomas Beckham (2007)
Manuscripts:
Turner LS, Cheng JC, Beckham TH, Keane TE, Norris JS, Liu X. Autophagy is
increased in prostate cancer cells overexpressing acid ceramidase and enhances
resistance to C6 ceramide. Prostate Cancer and Prostatic Diseases. 2011; 14, 30-37
Beckham TH, Lu P, Cheng JC, Zhao D, Turner LS, Zhang X, Hoffman S, Armeson KE,
Liu A, Marrison T, Hannun YA, and Liu X. Acid ceramidase-mediated production of
sphingosine 1-phosphate promotes prostate cancer invasion through up-regulation of
cathepsin B. Int J Cancer. 2012 PMID: 22322590
Beckham TH, Cheng JC, Marrison ST, Norris JS, Liu X. Interdiction of sphingolipid
metabolism to improve standard cancer therapies. Advances In Cancer Research. In
Press. 2012
Abstract:
Beckham TH, Cheng JC, Marrison ST, Liu X, Norris JS. Sphingosine 1-phosphate and
acid ceramidase modulate the subcellular localization of the PTEN tumor suppressor.
The Perry V. Halushka MUSC Student Research Day, Charleston, SC, November 2011
Marrison ST, Cheng JC, Beckham TH, Lu P, Liu A, Casey S, Liu X, Norris JS. Acid
Ceramidase Over Expression in Response to Cigarette Smoke Exposure, The Perry V.
Halushka MUSC Student Research Day, Charleston, SC, November 2011
Ceramidase Over Expression in Response to Cigarette Smoke Exposure. Hollings
Cancer Center Retreat Fall 2011
Cheng JC, Marrison ST, Beckham TH, Keane TE, Marshall DT, Liu X, Norris JS. The
Role Of Acid Ceramidase In The Failure Of Radiation Therapy For Prostate Cancer.
MUSC MSTP Research Day, Charleston, SC, March 24, 2012
Cheng JC, Liu X, Beckham TH, Keane TE, Hannun YA, Norris JS. Sphingolipid
Metabolism In The Radiation Resistance And Relapse Of Prostate Cancer. MUSC
MSTP Student Research Day, Charleston, SC, March 24, 2012
Marrison ST, Cheng JC, Beckham TH, Lu P, Liu X, Norris JS. Sphingosine 1phosphate receptor signaling in mesenchymal stem cells. MUSC MSTP Research Day,
Charleston, SC, March 24, 2012
75
metabolism in the radiation resistance and relapse of prostate cancer. Keystone
Symposium for Inflammation and Carcinogenesis. Dublin, Ireland, May 2012.
Beckham TH, Cheng JC, Marrison ST, Liu X, Norris JS.: Sphingosine 1-phosphate and
MUSC Lipid Signaling In Cancer Program Retreat, Charleston, SC, 2012
Gordon Research Conference on Glycolipid and Sphingolipid Biology, Lucca, Italy, 2012
Brandon Bentzley (2009)
Manuscript:
Bentzley B, Fender K, Aston-Jones G. Behavioral economics for the neuroscientist: A
review and new analytical approach. Psychopharmacology. Under Review, 2012
Abstract:
Bentzley B Aston-Jones G. Microinjection Of Muscimol Into The Subthalamic Nucleus
Attenuates Cocaine Consumption At High Price. MUSC MSTP Research Day,
Bentzley B, Fender K, Aston-Jones G. Behavioral economics for the neuroscientist:
Demand curve analysis of the within-session threshold procedure. 13th Annual
Frontiers in Neuroscience Research Day, Seabrook Island, SC, 2012
Jennifer Blakely (2007)
Manuscript:
Eaddy A, Kale V, Blakely J, Kolisetty N, Mock J, Cummings B, Megyesi J, Schnellmann
R. Genetic Ablation of Ca2+–Independent Phospholipase A2γ Induces Lipid
Peroxidation, Oxidative DNA Damage, and Loss of Phospholipid Homeostasis in Mouse
Kidney. Kidney International, Submitted, May 2012
Abstract:
Blakely JL, Garrett SM, Beeson CC, Schnellmann RG. 5-Hydroxytryptamine-Class 2
Receptor-Mediated Mitochondrial Biogenesis as a Potential Therapeutic Strategy for
Treatment of Acute Kidney Injury. American Society of Nephrology Kidney Week
Philadelpha, PA; November 9-12, 2011
Blakely JL, Garrett SM, Beeson CC, Schnellmann RG. Class 2 5-Hydroxytryptamine
Receptor-Mediated Mitochondrial Biogenesis as a Potential Therapeutic Strategy for
Treatment of Acute Kidney Injury. MUSC MSTP Research Day, Charleston, SC, March
24, 2012
76
Manuscripts:
Briggs LE, Kakarla J, Wessels A. The pathogenesis of atrial and atrioventricular septal
defects with special emphasis on the role of the dorsal mesenchymal protrusion.
Differentiation 2012 May 11. PMID: 22709652
Wessels A, van den Hoff MJ, Adamo RF, Phelps AL, Lockhart MM, Sauls K, Briggs LE,
Norris RA, van Wijk B, Perez-Pomares JM, Dettman RW, Burch JB. Epicardially derived
fibroblasts preferentially contribute to the parietal leaflets of the atrioventricular valves in
the murine heart. Dev Biol 2012 Apr 24. PMID: 22546693
Abstracts:
Briggs LE, Kakarla J, Phelps A, Wessels A The Role of Bone Morphogenetic Protein 4
in the Developing Inflow and Outflow Regions of the Heart. The Perry V. Halushka
MUSC Student Research Day, Charleston, SC, November 2011
Briggs L, Kakarla J, Phelps A, Wessels A. The Role of Bone Morphogenetic Protein 4
in the Developing Inflow and Outflow Regions of the Heart. MUSC MSTP Research
Day, Charleston, SC, March 24, 2012
Briggs LE, Phelps A, Kakarla J, van den Hoff M, Wessels A. BMP Signaling and
Atrioventricular Septation. Weinstein Cardiovascular Development Conference,
Chicago, IL, May 2-4, 2012
Norris RA, van Wijk B, Perez-Pomares JM, Dettman RW, Burch JB Epicardially derived
the murine heart. Weinstein Cardiovascular Development Conference, Chicago, IL, May
2-4, 2012
Robert Cameron (2011)
Abstracts:
Cameron RB, Lindsey C, Wills LP, Trager RT, Beeson CC, Schnellmann RG, Peterson
YK. Rational Development of Novel Biogenic Beta-Adrenergic Selective Agonists. The
Perry V. Halushka MUSC Student Research Day, Charleston, SC, November 2011
Cameron RB, Lindsey C, Wills LW, Trager, RT, Beeson, C, Schnellmann RG, Peterson
YK. Rational Development of Novel Biogenic Beta-Adrenergic Selective Agonists.
Joseph Cheng (2005)
Manuscripts:
Turner LS, Cheng JC, Beckham TH, Keane TE, Norris JS, Liu X. Autophagy is
increased in prostate cancer cells overexpressing acid ceramidase and enhances
resistance to C6 ceramide. Prostate Cancer and Prostatic Diseases. 2011; 14, 30-37
77
Liu A, Marrison T, Hannun YA, Liu X. Acid ceramidase-mediated production of
sphingosine 1-phosphate promotes prostate cancer invasion through upregulation of
cathepsin B. International Journal of Cancer. 2012 Feb 9. doi: 10.1002/ijc.27480.
[Epub ahead of print] PubMed PMID: 22322590.
Abstracts:
Ceramidase Over Expression in Response to Cigarette Smoke Exposure, The Perry V.
Metabolism In The Radiation Resistance And Relapse Of Prostate Cancer. MUSC
MSTP Student Research Day, Charleston, SC, March 24, 2012
metabolism in the radiation resistance and relapse of prostate cancer. Keystone
Symposium for Inflammation and Carcinogenesis. Dublin, Ireland, May 2012.
Danielle Clark (2009)
Abstracts:
Clark D, Perkel J, Fraser J, Rollins LG, Nie X, Singh I, Jenkins D. NAC and Vitamin D
Treatment Improving Hypoxic Ischemic Injury in the Neonatal Rat Model. The Perry V.
Treatment Improving Hypoxic Ischemic Injury in the Neonatal Rat Model. MUSC MSTP
Student Research Day, Charleston, SC, March 24, 2012
Treatment Improving Hypoxic Ischemic Injury in the Neonatal Rat Model. DCRI
Anniversary Conference and Retreat, Charleston, SC, March 29, 2012
78
Mohammad Dahrouj (2010)
Manuscripts:
Ablonczy Z, Dahrouj M, Tang PH, Liu Y, Sambamurti K, Marmorstein A D, Crosson CE.
Human Retinal Pigment Epithelium Cells as Functional Models for the RPE In Vivo.
Investigative Ophthalmology & Visual Science, 52(12), 8614-20. doi:10.1167/iovs.118021, 2011
Abstract:
Dahrouj M, Ablonczy Z Crosson CE. Natriuretic Peptides Protect the RPE From
Advanced Glycation End Products-Induced Barrier Breakdown. The Perry V. Halushka
MUSC Student Research Day, Charleston, SC, November 2011
Dahrouj M, McMillin JC, Crosson CE, Ablonczy Z. Using SD-OCT to Study the Effect of
VEGF on Fluid Transport Across the RPE in vivo. MUSC MSTP Student Research Day,
VEGF on Fluid Transport across the RPE In Vivo. Association for Research in Vision &
Ophthalmology (ARVO) Annual Meeting, Ft. Lauderdale, FL, May, 2012.
Vivar LJ, Liu Y, Goletz P, Dahrouj M, Tang PH, Ablonczy Z. Human Retinal Pigment
Epithelium Cells As Functional Models for Retinoid Metabolism. Association for
Research in Vision & Ophthalmology (ARVO) Annual Meeting, Ft. Lauderdale, FL, May,
2012.
Ablonczy A, Crosson CE, McMillin JC, Dahrouj M. SD-OCT To Link VEGF-induced
RPE Dysfunction with The Development of Wet-AMD. ARVO/ISIE Imaging Conference:
May 2012
Anna-Maria De Costa (2006)
Manuscripts:
De Costa AM, Young MR. Immunotherapy for head and neck cancer: advances and
deficiencies. Anticancer Drugs. 2011 Aug;22(7):674-81
De Costa AM, Schuyler CA, Walker DD, Young MR. Characterization of the evolution of
immune phenotype during the development and progression of squamous cell
carcinoma of the head and neck. Cancer Immunol Immunother. 2011 Nov 25 [Epub
ahead of print]
Walker DD, Reeves TD, De Costa AM, Schuyler CA, Young MR. The effects of 1,25dihydroxyvitamin D3 on tumor-associated immunosuppression in squamous cell
carcinoma of the head and neck. Cytokine. 2012 March 24 [Epub ahead of print]
79
De Costa AM, Justis D, Schuyler CA, Young MR. Administration of a vaccine
composed of dendritic cells pulsed with premalignant oral lesion lysate to mice bearing
carcinogen-induced premalignant oral lesions stimulates a protective immune response.
International Immunopharmacology. 2012 [Epub ahead of print]
Abstracts:
De Costa AM, Justis D, Schuyler C, Young R. Characterization of the evolution of
carcinoma of the head and neck. 11th Annual Hollings Cancer Center Research Retreat,
Charleston, SC, November 18, 2011
De Costa AM, Justis D, Schuyler C, Young R. Characterization of the Evolution of
Immune Phenotype During the Development and Progression of Squamous Cell
Carcinoma of the Head and Neck. The Perry V. Halushka MUSC Student Research
Day, Charleston, SC, November 2011
Justis DN, De Costa AM, Schuyler C, Young R. The Role of Th17 and Treg Cells
During HNSCC Carcinogenesis. The Perry V. Halushka MUSC Student Research Day,
Charleston, SC, November 2011
De Costa AM, Justis D, Schuyler C, Young R. Administration Of A Vaccine Composed
Of Dendritic Cells Pulsed With Premalignant Oral Lesion Lysate To Mice Bearing
Carcinogen-Induced Premalignant Oral Lesions Stimulates A Protective Immune
Response. MUSC MSTP Student Research Day, Charleston, SC, March 24, 2012
Danielle Desjardins (2011)
Manuscripts:
Ewen EP, Snyder CM, Wilson M, Desjardins D, Naya FJ. The Mef2A transcription
factor coordinately regulates a costamere gene program in cardiac muscle. J Biol
Chem. 2011 Aug 26;286(34):29644-53. Epub 2011 Jul 1.
Fast EM, Toomey ME, Panaram K, Desjardins D, Kolaczyk ED, Frydman HM.
Wolbachia enhance Drosophila stem cell proliferation and target the germline stem cell
niche. Science. 2011 Nov 18;334(6058):990-2. Epub 2011 Oct 20.
Layre E, Sweet L, Hong S, Madigan CA, Desjardins D, Young DC, Cheng TY, Annand
JW, Kim K, Shamputa IC, McConnell MJ, Debono CA, Behar SM, Minnaard AJ, Murray
M, Barry CE 3rd, Matsunaga I, Moody DB. A comparative lipidomics platform for
chemotaxonomic analysis of Mycobacterium tuberculosis. Chem Biol. 2011 Dec
23;18(12):1537-49.
Abstracts:
Desjardins DM, Beeson CC. Mitochondrial Dysfunction in Degenerative Pathologies.
80
Andre Eaddy (2004)
Manuscript:
Eaddy A, Cummings B, McHowat J, Schnellmann R. The Role of Endoplasmic
Reticulum Ca2+-Independent Phospholipase A2γ in Oxidant-induced Lipid Peroxidation,
Ca2+ Release, and Renal Cell Death. Toxicol Sci. 2012 May 15. [Epub ahead of print]
Eaddy A, Kale V, Blakely J, Kolisetty N, Mock J, Cummings B, Megyesi J,
Schnellmann R. Genetic Ablation of Ca2+–Independent Phospholipase A2γ Induces
Lipid Peroxidation, Oxidative DNA Damage, and Loss of Phospholipid Homeostasis in
Mouse Kidney. Kidney International, Submitted May 2012
Abstract:
Eaddy A, Walker C, Caton C. “Crack” the Case: Report of Cocaine/Levamisole-induced
Cutaneous Vasculitis. Presented at the Regional and National Society of General
Internal Medicine Meetings, February and May 2012
Christopher Gault (2003)
Manuscripts:
Gault CR. Obeid LM. Still benched on its way to the bedside: sphingosine kinase 1 as
an emerging target in cancer chemotherapy. [Review] Critical Reviews in Biochemistry
& Molecular Biology. 46(4):342-51, 2011 Aug.
Mullen TD, Clarke CJ, Gault CR, Snider AJ, Wu BX, Heffernan-Stroud LA, Hannun YA,
and Obeid LM. Complex regulation of sphingoid base metabolism by multiple
sphingolipid enzymes. Journal of Lipid Research. Submitted 2012
Abstract:
Selvam SP, Peterson YK, Gault CR, Obeid LM, Isaacs JS, Spiegel S, Smith CD,
Ogretmen B. Regulation of Telomerase By Sphingosine Kinase 2/Sphingosine-1Phosphate Signaling in Lung Cancer. The Perry V. Halushka MUSC Student Research
Day. Charleston, SC. November 2011
Mullen TD, Clarke CJ, Gault CR, Snider AJ, Wu BX, Heffernan LA, Hannun YA, Obeid
LM. Complex Regulation Of Sphingoid Base Metabolism By Multiple Sphingolipid
Enzymes. MUSC MSTP Research Day, Charleston, SC, March 24, 2012
George Russell Glenn (2010)
Abstract:
Glenn R, Tabesh A. Retrospective Noise Correction in Diffusional Kurtosis Imaging.
MUSC MSTP Student Research Day, Charleston, SC, March 24, 2012
George Daniel Grass (2008)
Manuscripts:
Grass GD, Bratoeva M, Toole BP. Regulation of Invadopodia Formation and Activity by
CD147. J Cell Science; 125(Part3): 777-788, 2012.
81
Dai L, Slomiany MG, Guinea MC, Bratoeva MP, Grass GD, Tolliver LB, Maria BL, Toole
BP. CD147-dependent heterogeneity in malignant and chemoresistant properties of
cancer cells. American Journal of Pathology. Submitted, May 2012
Wilkerson BA, Grass GD, Wing SB, Argraves WS, Argraves KM. S1P carrierdependent regulation of endothelial barrier: HDL-S1P prolongs endothelial barrier
enhancement as compared to albumin-S1P via effects on levels, trafficking and
signaling of S1P1. Journal of Biological Chemistry. Submitted, May 2012
Abstract:
Grass GD, Bratoeva M, Toole BP. EMMPRIN (CD147) is a Novel Regulator of
Invadopodia Formation and Activity. The Perry V. Halushka MUSC Student Research
Day. Charleston, SC. November 2011
Wilkerson BA, Grass GD, Wing SB, Argraves WS, Argraves KM. S1P carrierdependent regulation of endothelial barrier: HDL-S1P prolongs endothelial barrier
enhancement as compared to albumin-S1P via effects on levels, trafficking and
signaling of S1P1. The Perry V. Halushka MUSC Student Research Day. Charleston,
SC. November 2011
Grass GD, Bratoeva M, Toole BP. EMMPRIN (CD147) is a Novel Regulator of
Invadopodia Formation and Activity. MUSC MSTP Research Day, Charleston, SC,
March 24, 2012
Grass GD, Bratoeva M, Toole BP. Emmprin (CD147) is a Novel Regulator of
Invadopodia Formation and Activity. 8th Annual APSA Conference. Chicago, IL: April 2729, 2012
Linda Heffernan-Stroud (2004)
Manuscripts:
Heffernan-Stroud LA, Harper JL. Cutaneous Candida infection following radiation
therapy for breast cancer. Journal of Dermatological Case Reports, Submitted 2012
Heffernan-Stroud LA, Obeid LM. Sphingosine kinase 1 and cancer. Advances in
Cancer Research, Submitted 2012
Mullen TD, Clarke CJ, Gault CR, Snider AJ, Wu BX, Heffernan-Stroud LA, Hannun
YA, Obeid LM. Complex regulation of sphingoid base metabolism by multiple
sphingolipid enzymes. Journal of Lipid Research. Submitted 2012
Abstract:
Carroll BL, Heffernan-Stroud LA, Obeid LM. Regulation of Sphingosine Kinase 1 By
P53-Dependent Proteolysis. The Perry V. Halushka MUSC Student Research Day.
82
Casey O’Dell Holmes (2010)
Manuscript:
O'Dell CM, Das A, Wallace G 4th, Ray SK, Banik NL. Understanding the basic
mechanisms underlying seizures in mesial temporal lobe epilepsy and possible
therapeutic targets: a review. J Neurosci Res. 2012 May;90(5):913-24. doi:
10.1002/jnr.22829. Epub 2012 Feb 8.
Russell Jenkins (2004)
Manuscripts:
Jenkins RW, Cannick L, Harper J. Use of MammoSite balloon brachytherapy for early
stage breast cancer. Community Oncology 2011;8: 37-40.
Hernandez-Corbacho MJ, Jenkins RW, Clarke CJ, Hannun YA, Obeid LM, Snider AJ,
Siskind LJ. Accumulation of long-chain glycosphingolipids during aging is prevented by
caloric restriction. PLoS One. 2011;6(6):e20411
Truman JP, AI Gadban MM, Smith KJ, Jenkins RW, Mayroo N, Virella G, Lopes-Virella
MF, Bielawska A, Hannun YA, Hammad SM. Differential regulation of acid
sphingomyelinase in macrophages stimulated with oxidized LDL and oxidized LDL
immune complexes: role in phagocytosis and cytokine release. Immunology, In press.
2012
Jenkins RW, McDonald K, Greenberg CS. Numb Chin Syndrome in Acute Myeloid
Leukemia. American Journal of Medical Science. Accepted 2012
Salegio EA, Samaranch L, Jenkins RW, Clarke CJ, Lamarre C, Beyer J, Kells AP,
Bringas J, San Sebastian W, Richardson RM, Rosenbluth KH, Hannun YA, Bankiewicz
KS, Forsayeth J. Safety study of AAV2-mediated human acid sphingomyelinase
expression in the non-human primate brain. Human Gene Therapy. Submitted 2012.
Jenkins RW, Clarke CJ, Lucas J, Shabbir M, Wu B, Simbari F, Mueller J, Hannun YA,
Lazarchick J, Shirai K. Evaluation of the Role of Secretory Sphingomyelinase and
Bioactive Sphingolipids as Biomarkers in Hemophagocytic Lymphohistiocytosis. Blood.
Submitted 2012
Book Chapters
Mullen TD, Jenkins RW, Obeid LM, Hannun YA. Ceramide and Lipid Mediators in
Apoptosis In: Apoptosis: Physiology and Pathology. Eds. Reed JC, Green DR.
Cambridge University Press. pg. 88-105, 2011.
Christopher Bryce Johnson (2009)
Manuscripts:
Rubinstein MP, Cloud CA, Garrett TE, Moore CJ, Schwartz KM, Johnson CB, Craig
DH, Salem ML, Paulos CM, Cole DJ. Ex vivo interleukin-12-priming during CD8(+) T
cell activation dramatically improves adoptive T cell transfer antitumor efficacy in a
lymphodepleted host. J Am Coll Surg 214(4): 700-8, 2012
83
Johnson CB, Tikunov AP, Lee H, Wolak JE, Pediaditakis P, Romney DA,
Holmuhamedov E, Gamcsik MP, Macdonald JM. 13 C magnetic resonance
spectroscopy detection of changes in serine isotopomers reflects changes in
mitochondrial redox status. Magn Reson Med doi: 10.1002/mrm.23296, 2011
Abstracts:
Katikaneni L, Mulvihill DM, Johnson CB, Perkel J, Lambert D, Morgan P, Brown T,
Chang E, Caplan M & Jenkins D. Brain biomarkers for the development of motor injury
in term newborns exposed to chorioamnionitis; International Society for Developmental
Neuroscience Annual Meeting, Mumbai, India, January 2012
Johnson CB, Cloud CA, Rubinstein MP, Cole DJ. Total body irradiation enhances the
anti-tumor efficacy of adoptively transferred CD8+ T cells stimulated ex vivo with IL-12;
Hollings Cancer Center Research Retreat, Charleston, SC, March 2012
Johnson CB, Cloud CA, Rubinstein MP, Cole DJ. Total body irradiation enhances the
anti-tumor efficacy of adoptively transferred CD8+ T cells stimulated ex vivo with IL-12;
American Association of Immunologists, Boston, MA, May 2012
Abstract:
Johnson CB, Cloud CA, Rubinstein MP, Cole DJ.. Total body irradiation enhances the
anti-tumor efficacy of adoptively transferred CD8+ T cells stimulated ex vivo with IL-12.
Rebecca Weber Knackstedt (2008)
Manuscript:
Knackstedt R, Moseley D, Wargovich MJ. Epigenetic Mechanisms Underlying DietSourced Compounds in the Prevention and Treatment of Gastrointestinal Cancer.
Anticancer Agents Med Chem. In Press, 2012
Book Chapter:
Weber R, Taylor B, Engelman D. Laser Tissue Reactions and Dermatology. IN:
Basics in Dermatological Laser Applications (First edition). S. Karger AG, ed. Medical
and Scientific Publishers. 2011
Abstracts:
Knackstedt R. MCAT Success Strategies. SNMA 2011 Regional Conference,
Charleston, SC, October 2011.
Knackstedt R, Moseley D, Morris J, Wargovich MJ. The Vitamin D receptor and RXR
expression related to DNMT levels in a murine model of colitis. AACR Frontiers in
Cancer Prevention Research. Boston, MA, October 2011.
84
Knackstedt R, Moseley D, Morris J, Wargovich MJ. The Vitamin D receptor and RXR
expression related to DNMT levels in a murine model of colitis. The Perry V. Halushka
MUSC Student Research Day. Charleston, SC. November 2011
Knackstedt R. Student Panel on MCAT Success. 2012 Ernest E. Just Symposium,
Charleston, SC, February 2012.
Knackstedt R, Moseley D, Morris J, Wargovich MJ. VDR and RXRα Expression in
Murine Models of Colitis. MUSC MSTP Research Day, Charleston, SC, March 24, 2012
Craig Kutz (2010)
Manuscript:
Provost JJ, Rastedt D, Canine J, Ngyuen T, Haak A, Kutz C, Berthelsen N, Slusser A,
Anderson K, Dorsam G, Wallert MA. Urokinase plasminogen activator receptor induced
non-small cell lung cancer invasion and metastasis requires NHE1 transporter
expression and transport activity. Cell Onc. 2012 Jan 31. 35,2 - 95-110.
Abstracts:
Kutz C, Atkison J, Bernanke J, Kubalak S. Noncanonical, Rapid Downstream Crosstalk
Between TGFβ and Retinoic Acid Signaling Pathways As Revealed By the Proximity
Ligation Assay. The Perry V. Halushka MUSC Student Research Day. Charleston, SC.
November 2011
Kutz C, Atkison J, Bernanke J, Kubalak S. Noncanonical, Rapid Downstream Crosstalk
Between TGFβ and Retinoic Acid Signaling Pathways As Revealed By the Proximity
Ligation Assay. MUSC MSTP Research Day, Charleston, SC, March 24, 2012
Anthony Leonard (2007)
Manuscript:
Leonard A, Appleton KM, Luttrell LM, Peterson YK. A High-content, Live-cell, and Realtime Approach to the Quantitation of Ligand Induced β-arrestin2 and Class A /Class B
GPCR Mobilization. Microscopy and Microanalysis, Submitted May 2012
Abstracts:
Leonard AP, Perron N, Nasarre C, Beeson C, Rohrer B. Inhibition of Mitochondrial
Fission is Associated with Neuroprotection in Retinitis Pigmentosa. National MD/PhD
Student Conference, Keystone, CO, July 2011
Leonard AP, Perron N, Nasarre C, Beeson C, Rohrer B.Mitochondrial Fusion is Linked
to Bioenergetic Capacity and Cell Survival in a Cell-based Model of PDE6B-dependent
Retinitis Pigmentosa. The Perry V. Halushka MUSC Student Research Day. Charleston,
SC. November 2011
Leonard AP, Peterson YK, Perron NR, Beeson CC, Rohrer BM. High Content Imagingbased Automated Classification of Mitochondrial Morphology. MUSC MSTP Research
85
Leonard AP, Peterson YK, Perron NR, Beeson CC, Rohrer BM. High Content Imaging
Analysis of Mitochondrial Morphology in Retinal Degeneration. Frontiers in
Neuroscience Conference, Seabrook Island, SC, March 2012
Leonard AP, Peterson YK, Perron NR, Beeson CC, Rohrer BM. High Content Imaging
Reveals Mitochondrial Morphological Insights into the Mechanism of Neuroprotective
Drug Candidates in Retinitis Pigmentosa. National Clinical and Translational Sciences
Predoctoral Meeting, Mayo Clinic, Rochester, MN, May 2012
Sarah Tucker Marrison (2008)
Manuscript:
cathepsin B. International Journal of Cancer. 2012 Feb 9. doi: 10.1002/ijc.27480.
[Epub ahead of print] PubMed PMID: 22322590.
Beckham TH, Cheng JC, Marrison ST, Norris JS, Liu X. Interdiction of sphingolipid
metabolism to improve standard cancer therapies. Advances In Cancer Research. In
Press. 2012
Abstract:
Ceramidase Over Expression in Response to Cigarette Smoke Exposure. Hollings
Cancer Center Retreat Fall 2011
Ceramidase Over Expression in Response to Cigarette Smoke Exposure. The Perry V.
86
MUSC Lipid Signaling In Cancer Program Retreat, Charleston, SC, 2012
Gordon Research Conference on Glycolipid and Sphingolipid Biology, Lucca, Italy, 2012
Ahmad Mashmoushi (2007)
Abstracts:
Mashmoushi A, Hofbauer A, Donohue J, Ruiz P, Gilkeson G, Perl A, Oates J. Role Of
Endothelial Nitric Oxide Synthase (eNOS) in Lupus Nephritis. MUSC MSTP Research
Jamie Mills (2011)
Abstracts:
Mills JN, Bandurraga SG, Kramer R, Rumboldt T, Neumann C, Turner DP, Findlay VJ.
MicroRNA 510 as a Predictive Marker for Response to Platinum-Based Chemotherapy
in Triple Negative and HER2+ Breast Cancer Patients. MUSC MSTP Research Day,
Mills JN, Bandurraga SG, Kramer R, Rumboldt T, Neumann C, Turner DP, Findlay VJ.
MicroRNA 510 as a Predictive Marker for Response to Platinum-Based Chemotherapy
in Triple Negative and HER2+ Breast Cancer Patients. 1st Annual RNA Pathobiology in
Cancer Symposium, Charleston, SC, June 2012
Keely Morris (2006)
Abstracts:
Morris KL, Qiao F, He S, Atkinson C, Kulik L, Holers MV, Tomlinson S. Pathogenic
Natural Igm Antibodies Initiate The Inflammatory Response Important For Both
HepaticIschemia/Reperfusion Injury And Liver Regeneration After Partial Hepatectomy,
The Perry V. Halushka MUSC Student Research Day. Charleston, SC. November 2011
Morris KL, Qiao F, He S, Atkinson C, Kulik L, Holers MV, Tomlinson S. For Both
Hepatic Ischemia/Reperfusion Injury And Liver Regeneration After Partial Hepatectomy.
Khaled Moussawi (2005)
Manuscripts:
Shen H, Moussawi K, Zhou W, Toda S, Kalivas PW. Heroin relapse requires LTP-like
plasticity mediated by NR2B-containing receptors. Proceedings of the National
Academy of Sciences of the United States of America. 2011, Nov 29;108(48):19407-12
87
Kupchik YM, Moussawi K, Tang XC, Wang X, Kolokithas RA, Ogburn KB, Kalivas PW.
The effect of N-acetylcysteine on neurotransmission in the accumbens and relapse to
cocaine. Biological Psychiatry. Dec 1 [Epub ahead of print], 2011
Moussawi K, Riegel AC, Nair S, Kalivas PW. Extracellular glutamate: functional
compartments operate in different concentration ranges. Front Syst Neurosci. 5:94.
Epub 2011 Nov 24, 2011
Wang X, Moussawi K, Shen H, Kalivas PW. Role of mGlur5 neurotransmission in
reinstated cocaine-seeking. Addiction Biology. Accepted 2012
Stefanik MT, Moussawi K, Kupchik YM, Smith KC, Miller RL, Huff ML, Deisseroth K,
Kalivas PW, LaLumiere RT. Optogenetic inhibition of cocaine seeking in rats. Addiction
Biology. Submitted 2012
Thomas Mullen (2003)
Manuscripts:
Mullen TD, Obeid LM. Ceramide and Apoptosis: Exploring the Enigmatic Connections
Between Sphingolipid Metabolism and Programmed Cell Death. Anticancer Agents Med
Chem. 2011 Jun 27. [Epub ahead of print]. PMID: 21707511.
Mullen TD, Hannun YA, Obeid LM. Ceramide synthases at the centre of sphingolipid
metabolism and biology. Biochem J. 2012 Feb 1;441(3):789-802. PMID: 22248339.
Mullen TD, Sharma AK, Varma AK. Cervical osteomyelitis after placement of a selfexpanding plastic stent for palliation of dysphagia associated with chemoradiationinduced esophageal strictures. Head Neck. 2012 Feb 24 [Epub ahead of print]PMID:
22367919.
Mullen TD, Clarke CJ, Gault CR, Snider AJ, Wu BX, Heffernan-Stroud LA, Hannun YA,
Obeid LM. Complex regulation of sphingoid base metabolism by multiple sphingolipid
enzymes. Journal of Lipid Research. Submitted 2012
Book Chapters
Mullen TD, Jenkins RW, Obeid LM, Hannun YA. Ceramide and Lipid Mediators in
Apoptosis In: Apoptosis: Physiology and Pathology. Eds. Reed JC, Green DR.
Cambridge University Press. pg. 88-105, 2011.
Abstract:
Mullen TD, Clarke CJ, Gault CR, Snider AJ, Wu BX, Heffernan LA, Hannun YA, Obeid
LM. Complex Regulation Of Sphingoid Base Metabolism By Multiple Sphingolipid
Enzymes. MUSC MSTP Research Day, Charleston, SC, March 24, 2012
88
Daniel Neitzke (2010)
Abstract:
Neitzke D, Taylor J, Khouri G, Borckardt J, George M. Repetitive Transcranial Magnetic
Stimulation of the Left Dorsolateral Prefrontal Cortex Promotes Resilience, Prevents
Learned Helplessness. MUSC MSTP Research Day, Charleston, SC, March 24, 2012
Benjamin Newcomb (2009)
Manuscript:
Montefusco DJ, Newcomb B, Gandy JL, Brice SE, Matmati N, Cowart LA, Hannun YA.
Sphingoid bases and the serine catabolic enzyme CHA1 define a novel
Feedforward/Feedback mechanism in the response to serine availability. Journal of
Biological Chemistry. 2012, 287(12):9280-9.
Abstract:
Perry DM, Newcomb B, Wu B, Kitatani K, Hannun YA. Differential Regulation of IL-6
Production by Sphingolipid Catabolism: Role of Acid Sphingomyelinase in p38
Activation. MUSC MSTP Research Day, Charleston, SC, March 24, 2012
Armina Wiggins Omole
Manuscript:
Wiggins AT, Smith RJ, Shen HW, Kalivas PW. Integrins Modulate Relapse to CocaineSeeking. Journal of Neuroscience 2011, 31(45):16177-16184;doi:10.1523/
JNEUROSCI.3816-11.2011
Abstract:
Smith AW, Wiggins AT, Kalivas PW. Matrix Metalloproteinases in Reinstated Cocaine
Seeking, The Perry V. Halushka MUSC Student Research Day. Charleston, SC,
November 2011
Joseph Palatinus (2005)
Manuscripts:
Palatinus JA, Rhett JM, Gourdie RG.The connexin43 carboxyl terminus and cardiac
gap junction organization. Biochim Biophys Acta. 2012 Aug;1818(8):1831-43. Epub
2011 Aug 9.
Abstract:
Palatinus JA, Gourdie RG. A Connexin 43 C-terminal peptide increases PKC-epsilon
mediated phosphorylation of Connexin 43. International Gap Junction Conference,
Ghent, Belgium, July 2011
Palatinus JA, Gourdie RG.Phosphoregulation of the Cx43 Carboxy-terminus in Cardiac
Injury. The Perry V. Halushka MUSC Student Research Day. Charleston, SC.
November 2011
89
David Perry (2006)
Manuscripts:
Perry DM, Kitatani K, Roddy P, El-Osta M, Hannun YA. Identification and
Characterization of PP2C Activation by Ceramide. J Lipid Res. Accepted 2012
Abstract:
Perry DM, Kitatani K, Roddy P, El-Osta M, Hannun Y. Identification and
Characterization of PP2C Activation By Ceramide. The Perry V. Halushka MUSC
Student Research Day. Charleston, SC. November 2011
Perry DM, Newcomb B, Wu B, Kitatani K, Hannun YA. Differential Regulation of IL-6
Production by Sphingolipid Catabolism: Role of Acid Sphingomyelinase in p38
Activation. MUSC MSTP Research Day, Charleston, SC, March 24, 2012
Saleh Rachidi (2010)
Abstract:
Rachidi S, Qin T, Zheng J, Li Z. Identifying Cancer-Associated Inflammatory Genes: A
Data-Mining Approach. The Perry V. Halushka MUSC Student Research Day.
Rachidi S, Qin T, Zheng J, Li Z. Human Multi-Cancer Gene Expression Analysis
Defines an Inflammatory Cancer-Associated Molecular Pattern (iCAMP) with Prognostic
Significance. MUSC MSTP Research Day, Charleston, SC, March 24, 2012
Ryan Rhome (2004)
Manuscript:
Rhome R, Singh A, Kechichian T, Drago M, Morace G, Luberto C, Del Poeta M.
Surface localization of glucosylceramide in Cryptococcus neoformans allows targeting
as a potential anti-fungal. PLoS One. 2011 Jan 21;6(1):e15572.
Qureshi A, Wray D, Rhome R, Barry W, Del Poeta M. Detection of antibody against
fungal glucosylceramide in immunocompromised patients. Mycopathologia. 2012
Jun;173(5-6):419-25. Epub 2011 Oct 5.
Russo JK, Armeson KE, Rhome R, Spanos M, Harper J. Dose to level I and II axillary
lymph nodes and lung by tangential field radiation in patients undergoing
postmastectomy
radiation
with
tissue
expander
reconstruction. Radiation
Oncology, 2011 Dec 28;6:179.
Abstracts:
Rhome R, Wahlquist A, Garrett-Mayer E, Harper JL. Investigation of Epidemiological
Factors As Barriers To Indicated Radiation Therapy in Post-Mastectomy Breast Cancer
Patients in South Carolina. San Antonio Breast Cancer Symposium, San Antonio, TX,
2011
90
Douglas Roberts-Wolfe (2011)
Manuscript:
Roberts-Wolfe D, Sacchet M, Hastings E, Roth H and Britton W. Mindfulness training
alters emotional memory recall compared to active controls: support for an emotional
information processing model of mindfulness. Frontiers in Human Neuroscience 6:15.
doi:10.3389/fnhum.2012.00015, 2012
Sarah Brice Russo (2010)
Manuscripts:
Feedforward/Feedback mechanism in the response to serine availability. Journal of
Biological Chemistry. 2012, 287(12):9280-9.
Book Chapter:
Brice SE, Ross JS, Cowart LA. Sphingolipids in obesity, type 2 diabetes, and metabolic
disease. IN: Sphingolipids in Health and Disease. Erich Gulbins, ed. In press, 2012
Abstracts:
Brice SE, Van Laer A, Baicu CF, Geng T, Kasiganesan H, Zile M, Cowart LA. Bioactive
Sphingolipids Regulate Cardiac Hypertrophy and Autophagy in Lipid Overload: A Role
for Myristate and Its Derivatives. The Perry V. Halushka MUSC Student Research Day,
Charleston, SC, November 2011
Brice SE. A High-Myristate Diet Induces Sphingolipid-Dependent Cardiac Hypertrophy,
Dysfunction, and Autophagy: A Requirement for (Dihydro)Ceramide Synthase 5 in
Sphingolipid-Dependent Cardiac Autophagy. Southeastern Regional Lipid Conference –
Cashiers, NC, November, 2011
Brice SE, Baicu CF, Van Laer A, Geng T, Kasiganesan H, Zile MR, Cowart LA. The
Role of Sphingolipids and (Dihydro) Ceramide Synthase 5 in Diabetic Cardiomyopathy
in Mice. MUSC MSTP Research Day, Charleston, SC, March 24, 2012
Brice SE. The Role of Sphingolipids and (Dihydro)Ceramide Synthase 5 in Diabetic
Cardiomyopathy. Biochemistry Research and Methods Seminar, Medical University of
South Carolina, Charleston, SC, March, 2012
Brice SE. The Role of Sphingolipids and (Dihydro)Ceramide Synthase 5 in Diabetic
Cardiomyopathy. Society for Heart and Vascular Metabolism Annual Meeting, Oxford,
United Kingdom, June, 2012
Sahar Saddoughi (2006)
Manuscript:
Saddoughi SA, Garrett-Mayer E, Chaudhary U, O'Brien PE, Afrin LB, Day TA, Gillespie
MB, Sharma AK, Wilhoit CS, Bostick R, Senkal CE, Hannun YA, Bielawski J, Simon
GR, Shirai K, Ogretmen B. Results of a phase II trial of gemcitabine plus doxorubicin in
91
patients with recurrent head and neck cancers: serum C₁₈-ceramide as a novel
biomarker for monitoring response. Clin Cancer Res. 2011 Sep 15;17(18):6097-105.
Epub 2011 Jul 26.
Senkal CE, Ponnusamy S, Manevich Y, Meyers-Needham M, Saddoughi SA,
Mukhopadyay A, Dent P, Bielawski J, Ogretmen B. Alteration of ceramide synthase
6/C16-ceramide induces activating transcription factor 6-mediated endoplasmic
reticulum (ER) stress and apoptosis via perturbation of cellular Ca2+ and ER/Golgi
membrane network. J Biol Chem. 2011 Dec 9;286(49):42446-58. Epub 2011 Oct 19.
Abstracts:
Creel JS, Saddoughi S, Ogretmen B. The Effect of Fingolimod (FTY720) on Small Cell
Lung Cancer and Non-Small Cell Lung Cancer. The Perry V. Halushka MUSC Student
Research Day. Charleston, SC. November 2011
Jennifer Scott (2009)
Manuscript:
Cunningham MA, Naga OS, Eudaly JG, Scott JL, Gilkeson GS. Estrogen receptor
alpha modulates toll-like receptor signaling in murine lupus. Clinical immunology. 2012,
144(1):1-12.
Abstracts:
Scott JL, Cunningham M, Naga OS, Gilkeson G. Absence of Estrogen Receptor Alpha
Reduces Plasmacytoid Dendritic Cells and Type I Interferon Production in Lupus Prone
Mice. The Perry V. Halushka MUSC Student Research Day. Charleston, SC. November
2011
Scott JL, Cunningham M, Naga OS, Gilkeson G. Absence of Estrogen Receptor Alpha
Reduces the Number and Function of Plasmacytoid Dendritic Cells in Lupus Prone
Mice. MUSC MSTP Research Day, Charleston, SC, March 24, 2012
Amena Smith
Manuscript:
Smith AW, Rohrer B, Wheless L, Samantaray S, Ray S, Inoue J, Azuma M, Banik N.
The effect of calpain inhibition on visual pathway function during the course of chronicprogressive optic neuritis. J Neurosci. Submitted 2012
Abstract:
Smith AW, Wiggins AT, Kalivas PW. Matrix Metalloproteinases in Reinstated Cocaine
Seeking, The Perry V. Halushka MUSC Student Research Day. Charleston, SC,
November 2011
92
Joshua Smith (2008)
Manuscripts:
McDowell ML, Das A, Smith JA, Varma AK, Ray SK, Banik NL. Neuroprotective effects
of genistein in VSC4.1 motoneurons exposed to activated microglial cytokines.
Neurochem Int. 2011;59(2):175-84. PMCID: 3153433.
Smith JA, Das A, Ray SK, Banik NL. Role of pro-inflammatory cytokines released from
microglia in neurodegenerative diseases. Brain Res Bull. 2012;87(1):10-20.
Haar CP, Hebbar P, Wallace GCt, Das A, Vandergrift WA, 3rd, Smith JA, et al. Drug
resistance in glioblastoma: a mini review. Neurochem Res. 2012;37(6):1192-200.
Park S, Nozaki K, Guyton MK, Smith JA, Ray SK, Banik NL. Calpain Inhibition
Attenuated Morphological and Molecular Changes in Skeletal Muscle of Experimental
Allergic Encephalomyelitis Rats. J Neurosci Res. In press, 2012
Abstracts:
Smith JA, Das A, Wallace GC, Ray SK, Banik NL. Estrogen Receptor Agonists Protect
Against Glutamate Excitotoxicity In Spinal Cord Slice Cultures. The Perry V. Halushka
MUSC Student Research Day. Charleston, SC. November 2011
Smith JA, Das A, Wallace GC IV, Ray SK, Banik NL. Estrogen receptor agonists
protect against glutamate excitotoxicity in rat spinal cord slices. American Society for
Neurochemistry 2012 Meeting, Baltimore, MD.
Smith JA, Park S, Das A, Nozaki K, Krause JS, Banik NL. Identifying Telomerase as a
Target for Estrogen Neuroprotection Following Spinal Cord Injury. MUSC MSTP
Research Day, Charleston, SC, March 24, 2012
Kyle Strickland (2005)
Abstract:
Strickland KC, Krupenko SA. Regulation of Mitochondrial Protein Biosynthesis By
Formylation and Deformylation of MethionyltRNA. The Perry V. Halushka MUSC
Student Research Day. Charleston, SC, November 2011
Alton Sutter (2007)
Manuscript:
Evans ZP, Palanisamy AP, Sutter AG, Ellett JD, Ramshesh VK, Attaway H, Schmidt
MG, Schnellmann RG, Chavin KD. Mitochondrial uncoupling protein-2 deficiency
protects steatotic mouse hepatocytes from hypoxia/reoxygenation. Am J Physiol
Gastrointest Liver Physiol. 2012 Feb 1;302(3):G336-42. Epub 2011 Nov 17.
Abstracts:
Sutter A, Ellett J, Chavin K. Interleukin-10 And Kupffer Cells Protect The Fatty Liver
From Ischemia And Reperfusion Injury. The Perry V. Halushka MUSC Student
93
Sutter AG, Chavin KD. TLR4 Knockout Protects Obese Mice from Steatosis Associated
Liver Inflammation and Injury. MUSC MSTP Research Day, Charleston, SC, March 24,
2012
Peter Tang (2006)
Manuscripts:
Boyer NP, Tang PH, Higbee D, Ablonczy Z, Crouch RK, Koutalos Y. Lipofuscin and
A2E accumulate with age in the retinal pigment epithelium of Nrl-/- mice. Photochem
Photobiol 2012, 10.1111/j.1751-1097.2012.01127.x.
Tang PH, Buhusi M, Ma JX, Crouch RK. RPE65 is present in human green/red cones
and promotes photopigment regeneration in an in vitro cone cell model. J Neurosci
2011, 31(50):18618-18626
Ablonczy Z, Dahrouj M, Tang PH, Liu Y, Sambamurti K, Marmorstein AD, Crosson C.
Human retinal pigment epithelium cells as functional models for the RPE in vivo. Invest
Ophthalmol Vis Sci 2011, 52(12):8614-8620
Tang PH, Kono M, Koutalos Y, Ablonczy Z, Crouch RK. New insights into the retinoid
metabolism and cycle of the retina. Prog Retin Eye Res. In Press 2012
Tang PH, Vivar LJ, Dahrouj M, Liu Y, Oatis Jr. J, Ablonczy Z. Retinoid metabolism and
chromophore synthesis in cultured fetal human retinal pigment epithelium cells. Invest
Ophthalmol Vis Sci. Submitted 2012
Book Chapter:
Tang PH, Crouch RK. The essential role of retinoids as ligands for visual pigment
formation and survival of cone photoreceptors. IN: CRC Handbook of Photochemistry &
Photobiology. In Press 2012
Abstract:
Tang PH, Buhusi M, Crouch RK. RPE65 Protein is Present Within Human Cones to
Enhance Photopigment Regeneration for Vision. The Perry V. Halushka MUSC Student
Tang PH, Wheless L, Ma JX, Crouch RK. RPE65 Is Present Within Human Cone
Photoreceptors And Is Required For Efficient Cone Visual Pigment Regeneration. The
Vivar LJ, Liu Y, Goletz P, Dahrouj M, Tang PH, Ablonczy Z. Human Retinal Pigment
Epithelium Cells As Functional Models for Retinoid Metabolism. Association for
Research in Vision & Ophthalmology (ARVO) Annual Meeting, Ft. Lauderdale, FL, May,
2012.
94
Joseph Taylor (2008)
Manuscript:
Taylor JJ, Borckardt JJ, George MS (2012) Endogenous Opioids Mediate Left
Dorsolateral Prefrontal Cortex rTMS-Induced Analgesia. Pain 153, 1219-1225.
Book Chapter:
George MS, Taylor JJ, Short B: Treating the Depressions with Superficial Brain
Stimulation Methods (ECT, TES, TMS, rTMS, tDCS, epidural and subdural stimulation).
IN: Handbook of Brain Stimulation, Lozano and Hallett (eds.); Handbook of Clinical
Neurology, 3rd Series, Elsevier Press, 2012.
Abstract:
Taylor JJ, Borckardt JJ, George MS. Endogenous Opioids Mediate Left Dorsolateral
Prefrontal Cortex RTMS-Induced Analgesia. The Perry V. Halushka MUSC Student
Neitzke D, Taylor J, Khouri G, Borckardt J, George M. Repetitive Transcranial Magnetic
Stimulation of the Left Dorsolateral Prefrontal Cortex Promotes Resilience, Prevents
Learned Helplessness. MUSC MSTP Research Day, Charleston, SC, March 24, 2012
Taylor JJ, Borckard JJ, George MS. Endogenous opioids mediate left dorsolateral
prefrontal cortex rTMS-induced analgesia. 23rd Annual Meeting of the American
Neuropsychiatric Association, 2012.
Salatino A, Li X, Taylor JJ, Mu Q, Bohning D, George MS, Ricci. Imaging the neural
correlates of rightward neglect-like bias in healthy volunteers: an interleaved TMS/fMRI
study. 8th Federation of European Neuroscience Societies (FENS) Forum of
Neuroscience, 2012.
Hanlon CA, Canterberry M, Taylor JJ, DeVries W, Li X, Brown TS, George MS.
Differentiating neural networks with interleaved TMS-BOLD imaging. Society for Brain
Mapping and Therapeutics. Annual Meeting, Toronto, CA. June 2012.
Lee Wheless (2005)
Manuscripts:
Barnado A, Wheless L, Meyer AK, Gilkeson GS, Kamen DL. Quality of Life in Patients
with Systemic Lupus Erythematosus (SLE) Compared to Related Controls within a
Unique African American Cohort. Lupus 2012; 21:563-9.
Wheless L, Kistner-Griffin E, Jorgensen TJ, Ruczinski I, Berthier-Schaad Y, Kessing B,
Hoffman-Bolton J, Francis L, Shugart YY, Strickland PT, Kao WHL, Alani RM, Smith
MW, Alberg AJ. A community-based study of nucleotide excision repair polymorphisms
in relation to risk of non-melanoma skin cancer. J Invest Dermatol 2012; 132:1354-62.
95
Ruczinski I*, Jorgensen TJ* (co-first authors), Shugart YY, Berthier-Schaad Y, Kessing
B, Hoffman-Bolton J, Helzlsouer KJ, Kao WHL, Wheless L, Francis L, Alani RM,
Strickland PT, Smith MW, Alberg AJ. Nonmelanoma skin cancer as a marker of a
cancer-prone phenotype: Potential role of DNA repair gene variants. Carcinogenesis. In
press 2012
Jorgensen TJ, Ruczinski I, Wheless L, Shugart YY, Berthier-Schaad Y, Kessing B,
Hoffman-Bolton J, Helzlsouer KJ, Kao WHL, Francis L, Alani RM, Strickland PT, Smith
MW, Alberg AJ. Variants in Hedgehog genes and the risk of cancer. Cancer Epidemiol.
In press 2012
Alberg AJ, Jorgensen TJ, Ruczinski I, Wheless L, Shugart YY, Berthier-Schaud Y,
Kessing B, Hoffman-Bolton J, Helzlsouer KJ, Kao WHL, Francis L, Alani R, Smith MW,
Strickland PT. “DNA repair gene variants in relation to overall cancer risk: A populationbased study. Cancer Epidemiol Biomarkers Prev. Submitted 2012
The effect of calpain inhibition on visual pathway function during the course of chronicprogressive optic neuritis. J Neurosci. Submitted 2012
MW, Alberg AJ. Fibroblast growth factor 2 receptor polymorphisms associated with
increased risk of basal cell carcinoma. J Invest Dermatol. Submitted 2012
Wheless L, Kistner-Griffin E, Shugart YY, Kao WHL, Jorgensen TJ, Berthier-Schaad Y,
Kessing B, Hoffman-Bolton J, Ellerbe C, Francis L, Strickland PT, Alani RM, Smith MW,
Alberg AJ, Ruczinski I. Practical consideration in exploring gene-gene interactions: An
example using nucleotide excision repair pathway genes in relation to nonmelanoma
skin cancer. In preparation 2012
Wheless L*, Lam TK* (co-first authors), Jorgensen TJ, Ruczinski I, Berthier-Schaad Y,
Kessing B, Hoffman-Bolton J, Woodward L, Yao Y, Strickland PT, Smith MW, Alberg
AJ. XPD variant Lys751Gln is associated with increased risk of lung cancer
independent of smoking. In preparation 2012
Barnado A, Wheless L, Meyer AK, Gilkeson GS, Kamen DL. Pregnancy Outcomes
among African American Patients with Systemic Lupus Erythematosus (SLE) Compared
to Controls. In preparation 2012
Abstracts:
Tang PH, Wheless L, Ma JX, Crouch RK. RPE65 Is Present Within Human Cone
Photoreceptors And Is Required For Efficient Cone Visual Pigment Regeneration. The
96
Hoffman-Bolton J, Woodward L, Yao Y, Strickland PT, Kao WHL, Alani RM, Smith MW,
Alberg AJ. A Community-Based Study Of Nucleotide Excision Repair Polymorphisms
In Relation To Risk Of Non-Melanoma Skin Cancer. MUSC MSTP Research Day,
MW, Alberg AJ. A community-based study of nucleotide excision repair polymorphisms
in relation to risk of non-melanoma skin cancer. AACR annual meeting, Chicago, IL,
March 2012
Kessing B, Hoffman-Bolton J, Francis L, Strickland PT, Alani RM, Smith MW, Alberg AJ,
Ruczinski I. Practical consideration in exploring gene-gene interactions: An example
using nucleotide excision repair pathway genes in relation to nonmelanoma skin cancer.
Society for Investigative Dermatology annual meeting, Raleigh, NC, May 2012
Ryan Whitaker (2008)
Manuscript:
Smith MA, McInnes C, Whitaker RM, Lindsey CC, Comer RF, Beeson CC,
Schnellmann RG. Calpain 10 Homology Modeling with CYGAK and Increased
Lipophilicity Leads to Greater Potency and Efficacy in Cells. ACS Chem Biol. [Epub
ahead of print]. 2012
Abstract:
Whitaker RM, Covington MD, Schnellmann RG. (2011). Calpain 10 Loss Mediates
Increased Susceptibility to Nephrotoxicity. American Society of Nephrology Kidney
Week, Philadelphia, PA. November 2011
Whitaker RM, Smith MA, Covington, MD, Schnellmann, RG (2012). Depletion of Renal
Calpain 10 Mediates Early Renal Mitochondrial Dysfunction in Streptozotocin-Induced
Diabetic Rats. Keystone Symposium - Mitochondrial Dynamics and Function, Banff,
Alberta, Canada. March 2012
Whitaker R, Wills L, Schnellmann R. Stimulation of Mitochondrial Biogenesis with
PDE3 Inhibitors. MUSC MSTP Research Day, Charleston, SC, March 24, 2012
Parker Wilson (2005)
Manuscript:
El-Shewy HM, Sohn M, Wilson P, Lee MH, Hammad SM, Luttrell LM, Jaffa AA. Lowdensity lipoprotein induced expression of connective tissue growth factor via
transactivation of sphingosine 1-phosphate receptors in mesangial cells. Mol
Endocrinol. 2012 May;26(5):833-45. Epub 2012 Mar 15.
97
Xiaoyi Zhang (2008)
Abstracts:
Zhang X, Yu H, Kirkwood KL. MKP-1 deficiency enhances epithelial neoplasia in a
murine oral cancer model. The Perry V. Halushka MUSC Student Research Day.
Zhang X, Yu H, D’Silva N, Kirkwood KL. MKP-1 Deficiency Enhances Murine Oral
Neoplasia. MUSC MSTP Research Day, Charleston, SC, March 24, 2012
Zhang X, Yu H, D’Silva N, Kirkwood KL. MKP-1 deficiency enhances murine oral
neoplasia at the MUSC 10th Annual Head and Neck Multidisciplinary Research
Workshop, Charleston, SC, April 2012; 1st place
Zhang X, Yu H, D’Silva N, Kirkwood KL. MKP-1 deficiency enhances murine oral
neoplasia at the Keystone Symposia: The Role of Inflammation in Carcinogenesis,
Dublin, Ireland, May 2012
98
DENTAL SCIENTIST TRAINING PROGRAM
STUDENTS
DSTP
Students
Michael DeFee
Alfred Griffin
David Sentelle
Matriculation
Date
6/06
6/07
6/07
Haley Buff Lindner
6/07
Jessica Trombetta-eSilva 6/08
Bethany Herbert
6/10
Advisor
Dr. C. Parsons
Dr. K. Kirkwood
Dr. B. Ogretmen
Undergraduate School
Clemson University
Clemson University/
Drexel University (MS)
Dr. R. Muise-Helmericks College of Charleston
Dr. A. Bradshaw
Dr. K. Kirkwood
DSTP Graduates (2008-2012)
NAME
Undergraduate Year
Institution
DSTP
Graduated
Millie
College of
2010
Embree
Charleston
(BS)
Gabrielle Furman
Ferguson- University (BS)
Cannick
2009
Jonathan
Mitchell
College of
Charleston
(BS)
2008
Megan
Kibbey
Amal
Rastogi
Wheaton
College (BS)
Oklahoma
State University
(BS & MS)
2008
2008
Last known or
Current Position
Notes
Postdoc/Asst.
Professor
Columbia University
Dental School
Private Practice
with Father in
Charleston area
and raising family
Pediatric Residency
Program University
of Washington
Dental School
Assistant Professor
Tufts University
Private Practice
Periodontics
Virginia
Awarded NIH NRSA
F30 while at MUSC
Fundable Score
K99/R00
Awarded NIH NRSA
F30 while at MUSC
Awarded NIH NRSA
F30 while at MUSC
Awarded NIH NRSA
F30 while at MUSC
Awarded NIH NRSA
F30 while at MUSC
HIGHLIGHTS (2011-2012)
In the past year, Drs. Keith Kirkwood and Michael Kern have maintained the program as
viable and healthy through their leadership with the T32 trainees and the MUSC
administration. This past year was the first year of a five-year renewal period for the T32
NIDCR award. It was one of stable and incremental strengthening of the programmatic
changes designed and implemented over the past four years to ensure an excellent
research and training environment for DMD PhD students. For example the dynamic
changes over last four years included a new director of the program (Dr. Keith
99
Kirkwood), a new PhD Graduate Program approved by the MUSC Board of Trustees
(Craniofacial Biology), and new faculty recruitments to this Program. Most important to
the program is that our students are active researchers, publishing their data and
presenting it at national/international meetings.
1. More DSTP trainees transition to F awards: One assessment of the active
nature of the research our students are performing is their ability to obtain
funding for their research training. This past year saw a continuation of the trend
that our DSTP trainees have a high percentage of obtaining NIH-NRSA F30
awards; both Haley Buff-Lindner and Jessica Trombetta-eSilva received an F30
award. To date, ten of our eleven eligible DSTP trainees have been awarded an
NIH-NRSA award, which is far ahead of the national average. As they “graduate”
from the T32, this will allow us to recruit new students and thus expand the
training program. In this context a new DSTP student was added, Emilie Rosset,
who matriculated in June of 2012. Also new students have joined the PhD tract
of CranioFacial Biology thus increasing the core of Oral Health research trainees
at MUSC.
2. T32 Training program rebranded: The previous iteration of the T32 called the
training program the MUSC Dental Research Training Program. With the MUSC
Board of Trustees approving designation for the Center of Oral Health as a
University Center of Research Excellence, trying to integrate the COBRE along
with the T32, as well as expanding the program to include Ph.D. predoctoral
trainees, a new nomenclature was devised. The Training portion of the Center
for Oral Health Research is now designated as T-COHR.
The
Laboratory/Research Core portion is now designated L-COHR. Finally the
Clinical Core is designated as C-COHR. This rebranding does not change
anything for the DSTP trainees rather it incorporates a slight reorganization to
facilitate efficiency as well as ease of identification of people and their roles.
3. Second Annual CDM Scholar’s Day: One of the year’s major highlights was the
Second Annual College of Dental Medicine (CDM) Scholar’s Day held February
23rd 2012 at the new Bioengineering and Drug Discovery complex. This event
included an ASDA sponsored vendor fair, judged poster presentations, lunch and
a keynote speaker. Posters were presented by three different groups associated
with the Oral Health Research on campus: (i) every third year CDM student is
required to present their table clinic work, (ii) PhD and DMD/PhD students, and
finally the (iii) postdocs. Each of the three groups mentioned above had cash
awards for the first ($500), second ($250) and third ($100) places. A total of 58
posters were presented that day. The keynote speaker was Christopher H. Fox
DMD, MSc, DMSc, who presented a talk entitled “Advocating for Dental and
Craniofacial Research”. He is the Executive Director of the International
Association of Dental Research.
4. Training environment and DSTP applicant pool enhanced by a new R25
award: Dr. Kirkwood was recently awarded an R25 (1R25DE022677-01;
activation date 6/01/12) to support 8 undergraduates for the summer period to
perform oral health research in CDM labs. For the next five years of this award,
these positions allow us to expose the best and brightest undergraduates to oral
health research and the research environment at MUSC. Thus, not only is this
100
award recognition of an excellent training environment focusing on oral health,
but this will strengthen our DSTP since it will be an advantage in recruitment. It
should be noted that our two most recent T32 supported DSTP students
(Bethany Herbert and Emilie Rosset) participated in the SURP at MUSC and are
a testament to its ability to enhance recruitment.
5. Expected renewal of Dental P20 COBRE award will positively impact DSTP
training environment: The ten years of funding from NCRR via the COBRE
mechanism has dramatically enhanced the research environment of the College
of Dental Medicine; from recruiting new faculty, to initiating and enhancing
research cores with advanced technology (e.g. Laser capture microscopy, qRTPCR and MicroCT), it has helped to focus attention on research by ALL members
of the college. This positive impact continues with COBRE supported Junior
Faculty now receiving an R01, a few R03’s and an R21 in this current year. More
importantly for the next year is that the priority score for the COBRE 5 year
renewal was competitive and likely to get funded, starting July 1st, 2012.
AWARDS, HONORS AND MILESTONES 2011-2012
Student’s Name (Year of Matriculation)
David Sentelle (2007)
First Place: Ceramide Mediates LC3B Dependent Mitophagy and Tumor Suppression,
MUSC Scholars Day, Charleston SC, March 2012
National Research Service Award, Department of Health and Humans Services,
National Institutes of Health, National Institute of Dental and Craniofacial Research;
F30DE021295-01
First place in the MUSC CDM Scholars Day (PhD/DSTP category) Feb 2012
Ph.D. Dissertation Defense completed June 20, 2012
Alfred Griffin (2007)
Invited speaker at the Japanese Bone Research Symposium Feb 2012
Second place in the MUSC CDM Scholars Day (PhD/DSTP category) Feb 2012
Hatton Award Finalist AADR meeting Tampa March 2012
Michael DeFee (2006)
Ph.D. Dissertation Defense completed August 2011
Haley Buff Lindner (2007)
First Place Oral Presentation for Veterans Affairs (MUSC Student Research Day 2011)
First Place Oral Presentation PhD VII (MUSC Student Research Day 2011)
Third Place in the MUSC CDM Scholars Day (PhD/DSTP category) Feb 2012
Selected as Young Investigators Award Winner (Wound Healing Society, Atlanta 2012)
National Institutes of Health, National Institute of Dental and Craniofacial Research
101
Jessica Trombetta-eSilva (2008)
National Institutes of Health, National Institute of Dental and Craniofacial Research
PUBLICATIONS 2011-2012
Michael DeFee (2006)
Manuscripts:
Dai L, Qin Z, DeFee M, Toole B, Kirkwood KL, Parsons C. Kaposi sarcoma-associated
herpesvirus (KSHV) induces a functional tumor-associated phenotype for oral
fibroblasts. Cancer Lett 2012;318(2): 214-20
David Sentelle (2007)
Manuscripts:
Meyers-Needham M, Lewis JA, Gencer S, Sentelle RD, Saddoughi SA, Clarke CJ,
Hannun YA, Norell H, da Palma TM, Nishimura M, Kraveka JM, Khavandgar Z,
Murshed M, Cevik MO, Ogretmen B. Off-Target Function of the Sonic Hedgehog
Inhibitor Cyclopamine in Mediating Apoptosis via Nitric Oxide-Dependent Neutral
Sphingomyelinase 2/Ceramide Induction. Mol Cancer Ther. 2012 May;11(5):1092-102.
Epub 2012 Mar 27.
Abstracts
R. David Sentelle, Suriyan Ponnusamy, Can Senkal and Besim Ogretmen Role of
Ceramide in Inducing Lethal Autophagy in Head and Neck Cancer MUSC CDM
Scholar’s Day Feb 2012 Poster Presentation
R. David Sentelle, Suriyan Ponnusamy, Can Senkal and Besim Ogretmen Ceramide
suffocates cancer cells to death: Regulation of mitophagy by ceramide signaling.
American Association of Cancer Research-102nd Annual Meeting, Orlando FL April
2012
Alfred Griffin (2007)
Manuscripts:
Griffin III, A.C., Kern, M., Kirkwood, K.L. MKP-1 is Essential for Canonical Vitamin Dinduced RANKL Expression and Function. J. Mol. Endocrinology (provisionally
accepted)
Abstracts
A.C. Griffin, III and K.L. Kirkwood MKP-1 is Required for Canonical 1,25(OH)2D3signaling and Osteoclastogenesis Tampa 2012 American Association for Dental
Research Annual Meeting, March 24th, 2012 Hatton Competition finalist
102
Haley Buff Lindner (2007)
Manuscripts Beeson CC, Beeson GC, Buff H, Eldridge J, Zhang A, Seth A, Demcheva M, Vournakis
JN, Muise-Helmericks RC. Integrin-dependent Akt1 activation regulates PGC-1
expression and fatty acid oxidation. J Vasc Res. 2012;49(2):89-100.
Vournakis, J.N., Fischer, T., Lindner, H.B., Demcheva, M., Seth, A. and MuiseHelmericks, R.C. Poly-N-acetyl Glucosamine Nanofibers Derived from a Marine Diatom:
Applications in Diabetic Wound Healing and Tissue Regeneration. (2011)
Nanotechnology and Nanomedicine in Diabetes, in press.
Abstracts
Haley Buff Lindner, Aiguo Zhang, Juanita Eldridge, Marina Demcheva, Arun Seth,
Philip Tsichlis, Rick Visconti, Amy Bradshaw, John Vournakis and Robin C. MuiseHelmericks pGlcNAc nanofibers from a marine diatom stimulate a scarless wound
healing program Poster presentation at Student Research Day, Medical University of
South Carolina. (Nov., 2011), MUSC CDM Scholars Day (Feb. 2012), and the Wound
Healing Society Atlanta Georgia (April 2012) (This poster was selected to compete in
the Young Investigator Award Competition).
Jessica Trombetta-eSilva (2008)
Manuscript:
Jessica Trombetta-eSilva and Amy D Bradshaw. Review: The Function of SPARC as
a Mediator of Fibrosis. Open Rheumatology Journal March 2012.
Abstracts:
Jessica Trombetta-eSilva, Keith L. Kirkwood, and Amy D. Bradshaw SPARC is Critical
To Maintain Periodontal Ligament Integrity Collagen Gordon Conference: July 2011,
Poster Presentation
Jessica Trombetta-eSilva and Amy D. Bradshaw SPARC and the Collagenous
Extracellular Matrix of the Periodontal Ligament MUSC Student Research Day
11/04/2011, Oral Presentation
Jessica Trombetta-eSilva and Amy D. Bradshaw SPARC has a Two-Fold Mechanism
to Maintain Periodontal Ligament Integrity Department of Medicine Student Research
Day: 01/19/2012, Poster
Jessica Trombetta-eSilva and Amy D. Bradshaw Mechanisms of SPARC in
Periodontal Ligament Collagen Deposition:Transglutaminase Inhibition and Enhanced
Procollagen Processing Craniofacial Biology 2nd Annual Scholars Day: 02/24/2012,
Poster Presentation
103
Jessica Trombetta-eSilva and Amy D. Bradshaw Mechanisms of SPARC in
Periodontal Ligament Collagen Deposition:Transglutaminase Inhibition and Enhanced
Procollagen Processing American Association of Dental Research Conference: March
2012, Poster
Bethany Herbert (2010)
Publications
Sustained MAPK Activation with Aggregatibacter actinomycetemcomitans Causes
Inflammatory Bone Loss. Joni Dunmyer, Bethany Herbert, Qiyan Li, Robert Zinna,
Kylie Martin, Hong Yu, and Keith L. Kirkwood. (revised manuscript under review).
Abstracts:
B.A. Herbert, S. Talwar, Y. Padwad, V. Palanisamy. DNA Damage Activates MK2mediated Cell Cycle Control by Post-Transcriptional Regulation of Cyclin. Perry V.
Halushka MUSC Student Research Day, November 4th, 2011.
B.A. Herbert, S. Talwar, Y. Padwad, K. Kirkwood, V.Palanisamy. MK2 Mediates
Cell Cycle Control by Post-transcriptional Regulation of Cyclin B1. MUSC Dental
Scholars Day, February 23rd, 2012
B.A. Herbert, M. Gray, Q. Li, H. Yu, and K.L. Kirkwood. Tristetraprolin is Essential
to Maintain Alveolar Bone Homeostasis. American Association for Dental Research
Annual Meeting, March 24th, 2012
GOALS for 2012-2013
Re-evaluate our recruitment and admissions process
Increase the size and quality of our applicant pool
104
Molecular & Cellular Biology & Pathobiology Program
Donald R. Menick, Ph.D., Director
Division Directors
Dennis K. Watson, Ph.D.
Cancer Biology
Donald R. Menick, Ph.D.
Cardiovascular Biology
Joseph Schoepf, M.D.
Michael Rosol, Ph.D.
Cardiovascular Imaging
Steven A. Rosenzweig, Ph.D.
Cell Regulation
Keith L. Kirkwood, DDS, Ph.D.
Caroline Westwater, Ph.D.
Craniofacial Biology
Andy Wessels, Ph.D.
Genetics and Development
Eric R. Lacy, Ph.D.
Marine Biomedicine and
Environmental Science
Progress Committee
Dr. Craig Beeson
Dr. Edward L. Krug
Dr. Steven W. Kubalak
Dr. Donald R. Menick
Students
Student’s Name
Al Sarraf, Oday
Alge, Joseph
Allen, Emily
Matriculation
Date
2010
2010
2010
Aseem, Obaidullah
Bertin, Matthew
Briggs, Laura
Brunelle, Stephanie
2006
2008
2008
2005
Cantu, Theresa
Corum, Daniel
2011
2009
Cribben, Kathryn
Czajka, Caitlin
2009
2009
Mentor
Degree Sought
Dr. Craig Crosson
Dr. John Arthur
Dr. Demetri Spyropoulos
Dr. John Baatz
Dr. Scott Argraves
Dr. Peter Moeller
Dr. Andy Wessels
Dr. Francis Van Dolah
Ph.D.
M.D./Ph.D.
Ph.D.
Undecided
Dr. Robin MuiseHelmericks
Dr. Paul McDermott
Dr. Chris Drake
105
M.D./Ph.D.
Ph.D.
M.D./Ph.D.
Ph.D.
Graduated 5/12/12
Ph.D.
Ph.D.
Ph.D.
Ph.D.
Dahrouj, Mohammad III
Doheny, Brenna
e Silva, Jessica
Flanary, Jocelyn
Gandy Orr, Kathryn Alexa
2010
2010
2008
2004
2006
Dr. Craig Crosson
Dr. Louis Guillette, Jr.
Dr. Amy Bradshaw
Dr. Paul Becker
Dr. Lina Obeid
Gault, Christopher
2003
Dr. Lina Obeid
Gentile, Carmine
Goodson, Abby
Grass, G. Daniel
2008
2011
2008
Dr. Christopher Drake
Dr. Louis Guillette, Jr.
Dr. Bryan Toole
Grayson, Robyn
Griffin, Alfred III
Harikrishnan, Keerthi
Heffernan-Stroud, Linda
2007
2008
2004
Dr. John Baatz
Dr. Keith Kirkwood
Dr. W. Scott Argraves
Dr. Lina Obeid
Herbert, Bethany
Hung, Hsun-I
Jiang, Wenhui
Kimbrough, Denise
Knackstedt, Rebecca
Leighfield, Tod
Lindner, Amanda (Haley
Buff)
Lockhart, Marie
Lynch-Johnson, Jillian
Lyon, Barbara
2010
2008
2010
2009
2008
2005
2007
Dr. Keith Kirkwood
Dr. Anna-Lisa Nieminen
Dr. Besim Ogretmen
Dr. Donald R. Menick
Dr. Michael Wargovich
Dr. John Ramsdell
Dr. Muise-Helmericks
2007
2007
2005
Dr. Arno Wessels
Dr. Francis Van Dolah
Dr. Giacomo Ditullio
McCoy, Jessica
Moseley, Vondina
Mullen, Thomas
2010
2007
2003
Dr. Louis Guillette
Dr. Michael Wargovich
Dr. Lina Obeid
Palatinus, Joseph
Pleasant, Dorea
Pruett, Nathanael
2005
2010
2004
Renaud, Ludivine
Robichaux, Jacqulyne
Ross, Jessica
Samuel, Glady
2010
2010
2006
2005
Dr. Robert Gourdie
Dr. Dhan Kuppuswamy
Dr. Alexander
Awgulewitsch
Dr. Donald Menick
Dr. Ann Ramsdell
Dr. Ashley Cowart
Dr. Maria Trojanowska
Tirodkar, Tejas
2006
Strungs, Erik
2009
Dr. Christina VoelkelJohnson
Dr. Robert Gourdie
106
M.D./Ph.D.
Ph.D.
D.M.D, Ph.D.
Ph.D.
Ph.D.
Graduated 5/12/12
M.D./Ph.D.
Graduated 5/12/12
Ph.D.
Ph.D.
M.D./Ph.D.
Defended 5/24/2012
Ph.D.
D.M.D./Ph.D.
Ph.D.
M.D./Ph.D.
Graduated 5/12/12
D.M.D./Ph.D.
Ph.D.
Ph.D.
Ph.D.
M.D., Ph.D.
Ph.D.
Ph.D.
Ph.D.
Ph.D.
Ph.D.
Graduated 5/12/12
Ph.D.
Ph.D.
M.D./Ph.D.
Graduated 5/12/12
M.D./Ph.D.
Ph.D.
Ph.D.
Graduated 5/12/12
Ph.D.
Ph.D.
Ph.D.
Ph.D.
Graduated 5/12/12
Ph.D.
Graduated 5/12/12
M.D./Ph.D.
Wheeler, Jason
Wilkerson, Brent
Wilson, Parker
Zhang, Xiaoyi
2009
2007
2005
2008
Dr. Jeffrey Jones
Dr. Kelley Argraves
Dr. Louis Luttrell
Dr. Keith Kirkwood
Ph.D.
Ph.D.
M.D./Ph.D.
M.D./Ph.D.
STUDENTS’ PUBLICATIONS
Journals
Briggs LE, Kakarla J, Wessels A. The pathogenesis of atrial and atrioventricular septal
defects with special emphasis on the role of the dorsal mesenchymal protrusion.
Differentiation, 2012 May 11.
the murine heart. Dev Biol. 2012 Apr 24.
Brunelle SA, Van Dolah FM. Post-transcriptional regulation of S-phase genes in the
dinoflagellate, Karenia brevis. J Eukaryot Microbiol 58(4):373-382, 2011.
Ablonczy Z, Dahrouj M, Tang PH, Liu Y, Sambamurti K, Marmorstein AD, Crosson CE.
(2011). Human Retinal Pigment Epithelium Cells as Functional Models for the RPE In
Vivo. Investigative Ophthalmology & Visual Science, 52(12), 8614-20.,
doi:10.1167/iovs.11-8021.
Salas, Ponnusamy S, Senkal CE, Meyers-Needham M, Selvam SP, Saddoughi SA,
Apohan E, Sentelle RD, Smith C, Gault CR, Obeid LM, El-Shewy HM, Oaks J,
Santhanam R, Mrcucci G, Baran Y, Mahajan S, Fernandes D, Stuart R, Perrotti D,
Ogretman B. Sphingosine kinase-1 and sphingosine 1-phosphate receptor 2 mediate
Bcr Abl1 stability and drug resistance by modulation of protein phosphatase 2A. Blood
117(22): 5941-5952, 2011.
Gault CR, Obeid LM. Still benched on its way to the bedside: sphingosine kinase 1 as
an emerging target in cancer chemotherapy. Crit Rev Biochem Mol Biol 46(4): 342-351,
2011.
Grass, GD Bratoeva M, Toole BP. Regulation of Invadopodia Formation and Activity by
CD147. J Cell Science; 125(Part3): 777-788, 2012.
Dai L, Slomiany MG, Guinea MC, Bratoeva MP, Grass GD, Tolliver LB, Maria BL, Toole
BP. CD147-dependent heterogeneity in malignant and chemoresistant properties of
cancer cells. (submitted-under revision).
107
Heffernan-Stroud LA, Helke KL, Jenkins RW, De Costa AM, Hannun YA, Obeid LM.
Defining a role for sphingosine kinase 1 in p53-dependent tumors. Oncogene 31(9):
1166-1175, 2012.
Hung H-I, Lemasters JJ, Nieminen A-L.(2012) Mitochondrial Iron Uptake Through
Mitoferrin2 Sensitizes Human Head and Neck Squamous Carcinoma Cells to
Photodynamic Therapy (In process of submitting).
Shalini S, Hung HI, Quiogue G, Lemasters JJ, Nieminen AL.(2012) Lysosomal signaling
enhances mitochondria-mediated photodynamic therapy in a431 cancer cells: role of
iron, Photochemistry and Photobiology. 2012 Mar; 88 (2):461-8.
Hung H-I, Quiogue G, Lemasters JJ, Nieminen A-L, "Signaling from lysosomes to
mitochondria sensitizes cancer cells to photodynamic treatment" Proc. SPIE 7886,
78860C, 2011.
Meyers-Needham M, Ponnusamy S, Gencer S, Jiang W, Thomas RJ, Senkal CE,
Ogretmen B.
Concerted functions of HDAC1 and microRNA-574-5p represss
alternatively spliced ceramide synthase 1 expression in human cancer cells. EMBO Mol
Med 4(2): 78-92, 2012.
Johnson JG, Morey JS, Neely MG, Ryan JC, Van Dolah FM. Transcriptome remodeling
associated with chronological aging in the dinoflagellate, Karenia brevis. Mar Genomics
5: 15-25, 2012.
Knackstedt RW, Moseley VR, Wargovich MJ. (2012) Epigenetic Mechanisms
Underlying Diet-Sourced Compounds in the Prevention and Treatment of
Gastrointestinal Cancer. Anti-Cancer Agents in Medicinal Chemistry (in press).
Beeson CC, Beeson GC, Buff H, Eldridge J, Zhang A, Seth A, Demcheva M, Vournakis
JN, Muise-Helmericks RC. Integrin-dependent Akt1 activation regulates PGC-1
expression and fatty acid oxidation . J Vasc Res. 49(2):89-100, 2012.
Vournakis, J.N., Fischer, T., Lindner, H.B., Demcheva, M., Seth, A. and MuiseHelmericks, R.C. Poly-N-acetyl Glucosamine Nanofibers Derived from a Marine Diatom:
Applications in Diabetic Wound Healing and Tissue Regeneration. (2011), in
Nanotechnology and Nanomedicine in Diabetes, in press.
Wessels A, van den Hoff MJ, Adamo RF, Lockhart M, Sauls K, Briggs LE, Phelps A,
van Wijk B; Perez-Pomares JM, Dettman RW, Burch JB. Epicardially-derived
Fibroblasts and their Contribution to the Ventricular Myocardium and the Atrioventricular
Valves. Dev Biol. June 15; 366(2): 111-24. 2012.
Lockhart M, Wirrig E, Phelps A, Wessels A. Extracellular Matrix and Heart
Development. Birth Defects Res A Clin Mol Teratol. June; 91(6): 535-50, 2011.
108
Lyon BR, Lee PA, Bennett JM, DiTullio GR, Janech MG. proteomic analysis of a sea-ice
diatom: salinity acclimation provides new insight into the dimethylsulfoniopropionate
production pathway. Plant Physiol 157(4): 1926-1941, 2011.
Mullen TD, Hannun YA, Obeid LM. Ceramide synthases at the centre of spingolipid
metabolism and biology. Biochem J 441(3):789-802, 2012.
Mullen TD, Obeid LM. Ceramide and apoptosis: exploring the enigmatic connections
between sphingolipid metabolism and programmed cell death. Anticancer Agents med
Chem 12(4): 340-363, 2012.
Palatinus JA, Rhett JM, Gourdie RG. The connexin43 carboxyl terminus and cardiac
gap junction organization. Biochim Biophys Acta 1818(8): 1831-1843, 2012.
Palatinus JA, Rhett JM, Gourdie RG. Enhanced PKCε mediated phosphorylation of
connexin43 at serine 368 by a carboxyl-terminal mimetic peptide is dependent on injury.
Channels (Austin) 5(3): 236-240, 2011.
Baicu CF, Zhang Y, Van Laer AO, Renaud L, Zile MR, Bradshaw AD. “Effects of the
Absence of Procollagen C-Endopeptidase Enhancer-2 (PCOLCE-2) On Myocardial
Collagen Accumulation in Chronic Pressure-Overload”. Am J Physiol Heart Circ Physiol.
2012 May 18. [Epub ahead of print].
Menick DR, Li MS, Chernysh O, Renaud L, Kimbrough D, Kasiganesan H, Mani SK.
“Transcriptional Pathways and Potential Therapeutic Targets in the Regulation of Ncx1
Expression in Cardiac Hypertrophy and Failure”. Accepted by New York Academy of
Science Journal, 2012.
Kendall RT, Strungs EG, Rachidi SM, Lee MH, El-Shewy HM, Luttrell DK, Janech MG,
Luttrell LM. The beta-arrestin pathway-selective type 1A angiotensin receptor (AT1A)
agonist [Sar1, IIe4, II38]angiotensin II regulates a robust G protein-independent signaling
network. J Biol Chem 286(22):19880-19891, 2011.
Trombetta-eSilva J, Bradshaw AD. The Function of SPARC as a Mediator of Fibrosis.
Review submitted to Open Rheumatology Journal March 2012.
Wilkerson BA, G. Grass GD, Wing SB, Argraves WS, Argraves KM. S1P carrierdependent regulation of endothelial barrier: HDL-S1P prolongs endothelial barrier
enhancement as compared to albumin-S1P via effects on levels, trafficking and signaling
of S1P1. (submitted-under revision)
109
Presentations
Oral
Allen, E. Environment & Security Conference Symposium, Hollings Marine Laboratory
(Fort Johnson), Charleston, SC, February 24th, 2012.
Al Sarraf O., Yates PW, Crosson CR. Valproic Acid Reduces Retinal Ganglion Cell
Degeneration in Ocular Hypertensive Rats. 46TH Annual Perry V. Halushka MUSC
Student Research Day, November 4, 2011.
Aseem O, Smith BT, Cooley MA, Argraves WS. Cubilin is Essential for Maintaining
Blood HDL Levels. 46TH Annual Perry V. Halushka MUSC Student Research Day,
November 4, 2011.
Al Sarraf O., Yates PW, Fan J, Crosson CE. Protein Acetylation as a Predictor of
Retinal Injury. Association for Research in Vision and Ophthalmology, Ft. Lauderdale,
FL, May 2012.
Bertin MJ, Zimba PV, Beauchesne KR, Huncik KM, Moeller P. The Contribution of
Fatty Acid Amides to Prymnesium Parvum Toxicity. 46TH Annual Perry V. Halushka
MUSC Student Research Day, November 4, 2011.
Dahrouj M, McMillin JC,
Effect of VEGF on Fluid
Univ of South Carolina,
Carolina, Charleston, SC.
Crosson CE, Zsolt Ablonczy. Using SD-OCT to Study the
Transport across the RPE In Vivo. Ophthalmology, Medical
Charleston, SC; School of Medicine, University of South
ARVO 2012.
Dahrouj M, Ablonczy Z, Crosson C. Natriuretic Peptides Protect the RPE from
Advanced Glycation End Products-Induced Barrier Breakdown. MUSC Student’s
Research Day.
VEGF on Fluid Transport across the RPE In Vivo. MSTP Retreat.
Gentile C., Muise-Helmericks, RC, Drake CJ. Cardiovascular Developmental Biology
Center (CDBC) Symposium 2012, Charleston, SC (2012). “VEGF-mediated
Phosphorylation of eNOS Regulates Angioblast and Endothelial Cell Proliferation.”
Griffin AC, Kirkwood KK. MKP-1 is Required for Canonical 1,25(OH)2D3-signaling and
Osteoclastogenesis. MUSC Perry V. Halushka Student Research Day, November
2011.
Harikrishnan K, Cooley MA, Twal WO, Fresco VM, Kern CB, Argraves WS. Fibulin-1
Regulation of HB-EGF/ErbB1 Signaling in Cardiac Valvulogenesis. MUSC Perry V.
Halushka Student Research Day, November 2011.
110
Hung H-I. ASP (The 36th Meeting of American Society for Photobiology) Montreal,
Canada, June 23-28, 2012.
Hung H-I. SPIE (The International Society for Optics and Photonics) San Francisco
CA, 2011.
Hung H-I. SCCP (South Carolina College of Pharmacy) Charleston SC, Oct 2011.
Johnson JG, Van Dolah FM. An Integrated Bioinformatic and Biochemical Approach to
Identifying Caspase Activity During the Aging Process of Karenia Brevis MUSC Perry
V. Halushka Student Research Day, Charleston, SC, November 2011.
Knackstedt R. VDR and RXR? Expression in Murine Models of Colitis. 2012 MUSC
MSTP Research Day. Charleston, SC, March 2012.
Knackstedt R. Student Panel on MCAT Success.
Charleston, SC, February 2012.
2012 Ernest Just Symposium.
Lindner HB, Zhang A, Eldridge J, Demcheva M, Seth A, Tsichlis P, Visconti R,
Bradshaw A, Vournakis J, Muise-Helmericks RC. pGlcNAc nanofibers from a marine
diatom stimulate a scarless wound healing program. 46TH Annual Perry V. Halushka
MUSC Student Research Day, November 4, 2011.
Bradshaw A, Vournakis J, Muise-Helmericks RC. pGlcNAc nanofibers stimulate a
scarless wound healing program. Wound Healing Society, Atlanta Georgia (April 19-22,
2012) (Abstract selected to compete in the Young Investigator Award Competition- Oral
presentation).
Lockhart M. Differential Contribution of Epicardially-Derived Cells to the Parietal
Leaflets of the AV Valves in the Murine Heart. Weinstein Cardiovascular Development
Conference (Chicago), May 2012.
Lockhart M. Contribution of Epicardially-Derived Cells to the AV Valvuloseptal
Complex. MUSC Cardiovascular Developmental Biology Center Symposium
(Charleston, SC), March 2012.
Lockhart M. Transcriptional Regulation of Cartilage Link Protein 1 in the Developing
Heart. 46TH Annual Perry V. Halushka MUSC Student Research Day, November 4,
2011.
Palatinus JA, Gourdie RG. Phosphoregulation of the Cx43 Carboxy-terminus in
Cardiac Injury. 46TH Annual Perry V. Halushka MUSC Student Research Day,
November 4, 2011.
111
Renaud L. Does Acetylation Regulate microRNA Expression in Myocardial Infarction?
46TH Annual Perry V. Halushka MUSC Student Research Day, November 4, 2011.
Robichaux, J. Mammary Gland Laterality in Normal and Neoplastic Development.
MUSC Hollings Cancer Retreat, September 2011.
MUSC Hollings Cancer Retreat, February 2012.
Tirodkar TS, Voelkel-Johnson C.
Elevation of CerS6 Expression Triggers
Compensation Via the Ceramidase Pathway in Colon Cancer Cells. 46TH Annual Perry
V. Halushka MUSC Student Research Day, November 4, 2011.
Trombetta-eSilva J, Bradshaw AD. SPARC and the Collagenous Extracellular Matrix
of the Periodontal Ligament. 46TH Annual Perry V. Halushka MUSC Student Research
Day, November 4, 2011.
Wheeler JB, Watson DK, Garrett-Mayer E, Reed CE. Differential Inflammatory
Response Could Contribute To The Disparity Of Barrett's Esophagus and Esophageal
Adenocarcinoma In European Versus African Americans, MUSC Perry V. Halushka
Student Research Day, Charleston, SC, November 2011.
Zhang X, Yu H, Kirkwood KL. MKP-1 deficiency enhances epithelial neoplasia in a
murine oral cancer model at the 46TH Annual Perry V. Halushka MUSC Student
Research Day, November 4, 2011.
Zhang X, Yu H, D'Silva NJ, Kirkwood KL. MKP-1 deficiency enhances murine oral
neoplasia at the MUSC 10th Annual Head and Neck Multidisciplinary Research
Workshop, Charleston, SC, April 2012.
Poster
Allen EM, Baatz JE, Newton D, Mancia A, Spyropoulos DD. Comparative analysis of
differentiative capacity in Pygmy Sperm Whale and terrestrial mammal inducedpluripotent stem cells (iPSCs). Presented at: Gordon Research Conference: Oceans &
Human Health, June 2-8, University of New England, Biddeford, ME.
Allen EM, Baatz JE, Spyropoulos DD. Development of a Next-Generation Lung Tissue
Biorepository the Study Health and Disease. Presented at: 11th Annual HCC Research
Retreat, November 18, 2011, Daniel Island Club, Charleston, SC.
Allen EM, Spyropoulos DD, and Baatz JE. A Comparison of the Differentiative
Capacities of Induced Pluripotent Stem Cell (iPSC)-Derived Fibroblasts and Other
Primary Fibroblasts in Hypoxia. Presented at: 46TH Annual Perry V. Halushka MUSC
Student Research Day, November 4, 2011.
112
Allen EM, Baatz JE, Mancia A, McFee WE, Newton DA, Spyropoulos DD. A
comparative analysis of oxidative stress-response in induced pluripotent stem (iPS) and
embryonic stem cells from terrestrial vs aquatic mammals. Poster presented at: MBES
Student Research Open House (SROH) July 22nd, 2011, Fort Johnson, SC.
Briggs LE, Phelps A, Kakarla J, van den Hoff M, Wessels A. BMP Signaling and
Atrioventricular Septation. 2012 Weinstein Cardiovascular Development Conference.
the murine heart. 2012 Weinstein Cardiovascular Development Conference.
Briggs LE, Kakarla J, Phelps A, Wessels A. The Role of Bone Morphogenetic Protein 4
in the Developing Inflow and Outflow Regions of the Heart. 2011 Perry V. Halushka
Student Research Day.
Corum DG, Muise-Helmericks RC. AKT3 Promotes Nuclear Retention Of PGC-1 And
ER Alpha By Regulation Of The Major Nuclear Export Protein, CRM-1. 46TH Annual
Perry V. Halushka MUSC Student Research Day, November 4, 2011.
Cribben K and McDermott P. The Role of Estrogen-Related Receptors in
Cardiomyocyte Metabolic Adaptation to Oxidative Stress. Medical University of South
Carolina Department of Medicine Research Day, Charleston, South Carolina, January
2012
Cardiomyocyte Metabolic Adaptation to Oxidative Stress. 46TH Annual Perry V.
Halushka MUSC Student Research Day, November 4, 2011.
Cardiomyocyte Metabolic Adaptation to Oxidative Stress. Molecular and Cellular Biology
Doctoral Candidate Oral Qualifying Examination, Medical University of South Carolina,
Charleston, South Carolina, October 2011.
Ablonczy Z, Crosson J, McMillin JC, Dahrouj M. SD-OCT To Link VEGF-induced RPE
Dysfunction with The Development of Wet-AMD. ARVO/ISIE Imaging Conference: May
2012.
Lucero J. Vivar, Yueying Liu, Patrice Goletz, Mohammad Dahrouj, Peter H. Tang, Zsolt
Ablonczy. Human Retinal Pigment Epithelium Cells As Functional Models for Retinoid
Metabolism . Ophthalmology, Neurosciences - Ophthalmology, Medical University of
South Carolina, Charleston, SC. ARVO 2012
113
Gentile C., Muise-Helmericks RC, Drake CJ. “VEGF-Mediated Phosphorylation of
eNOS Regulates Angioblast and Endothelial Cell Proliferation.” Arteriosclerosis,
Thrombosis and Vascular Biology (ATVB) Scientific Sessions 2012, Chicago, IL (2012).
Grass D, Bratoeva M, Toole BP. Regulation of Invadopodia Formation and Activity By
Emmprin (CD147). 46TH Annual Perry V. Halushka MUSC Student Research Day;
November 4, 2011.
Grass GD, Bratoeva M, Toole BP. “EMMPRIN (CD147) is a Novel Regulator of
Invadopodia Formation and Activity.” 8th Annual APSA Conference. Chicago, IL: April
27-29, 2012.
Grass GD, Bratoeva M, Toole BP. “EMMPRIN (CD147) is a Novel Regulator of
Invadopodia Formation and Activity.” 22nd Annual MUSC MSTP Research Day; March
24, 2012.
Cooper SL, Grass GD, Armeson K, Garrett-Mayer E, Sharma AK.
“Cervical
Esophageal Cancer: A Population-based Study.” American Society of Radiation
Oncology 54th Annual Meeting 2012 (submitted).
Herbert BA, Talwar S, Padwad Y, Palanisamy V. DNA Damage Activates MK2mediated Cell Cycle Control By Transcriptional Regulation of Cyclin. 46TH Annual Perry
V. Halushka MUSC Student Research Day, November 4, 2011.
Hung H-I. AACR (American Association for Cancer Research) Chicago IL, April 2012
-HCC Retreat (MUSC Hollings Cancer Center Retreat) Charleston SC, Nov 2011
Kimbrough D. Inhibition Of Histone Deacetylase Activity Represses Matrix
Metalloproteinase-9 Induction by Regulating of Macrophage Secretion of MMPs to
Preserving Extracellular Matrix Post Myocardial Infarction. MUSC Department of
Medicine Research Day
Kimbrough D. Inhibition Of Histone Deacetylase Activity Represses Matrix
Metalloproteinase-9 (MMP-9) Induction Through Regulation of Macrophage Polarization
to Control Secretion of MMP-9. AHA BCVS 2012, New Orleans, LA.
Knackstedt R. MCAT Success Strategies.
Charleston, SC, October 2011.
SNMA 2011 Regional Conference.
Knackstedt R. The Vitamin D receptor and RXR expression related to DNMT levels in
a murine model of colitis. AACR Frontiers in Cancer Prevention Research. Boston,
MA, October 2011.
Knackstedt, R. The Vitamin D receptor and RXR expression related to DNMT levels in
a murine model of colitis. 46TH Annual Perry V. Halushka MUSC Student Research
114
Knackstedt R, Moseley D, Wargovich MJ. Epigenetic Mechanisms Underlying DietSourced Compounds in the Prevention and Treatment of Gastrointestinal Cancer.
Anticancer Agents Med Chem, 2012 in press.
scarless wound healing program. CDM Scholars Day, February 2012.
scarless wound healing program. MUSC MSTP Student Research Retreat, March 24,
2012.
Lockhart M. Transcriptional Regulation of Cartilage Link Protein 1 in the Developing
Heart. Poster Presentation, Weinstein Cardiovascular Development Conference
(Chicago, IL), May 2012.
Moseley V. "Epigenetic Modification of Human Colon Cancer by EGCG" - 10th Annual
AACR Frontiers in Cancer Prevention Research, Boston, MA - October 22-25, 2011.
Moseley V. "Epigenetic Modification of Human Colon Cancer by EGCG" - 5th Annual
National Conference on Health Disparities, Charleston, SC - November 30-Dec 3, 2011.
Trombetta-eSilva J, Kirkwood KL, Bradshaw AD. SPARC is Critical To Maintain
Periodontal Ligament Integrity. Collagen Gordon Conference: July 2011.
Trombetta-eSilva J, Bradshaw AD. SPARC has a Two-Fold Mechanism to Maintain
Periodontal Ligament Integrity. Department of Medicine Student Research Day:
01/19/2012.
Trombetta-eSilva J, Bradshaw AD. Mechanisms of SPARC in Periodontal Ligament
Collagen Deposition: Transglutaminase Inhibition and Enhanced Procollagen
Processing. Craniofacial Biology 2nd Annual Scholars Day: 02/24/2012.
Trombetta-eSilva J, Bradshaw AD. Mechanisms of SPARC in Periodontal Ligament
Collagen Deposition: Transglutaminase Inhibition and Enhanced Procollagen
Processing. American Association of Dental Research Conference: March 2012.
Moschella P, McKillop J, Pleasant D, Balasubramanian S, Kuppuswamy D. mTORC2mediated prosurvival Signaling Requires PKCε in Adult Feline Cardiomyoctes. MUSC
Department of Medicine Research Day, Charleston, SC , January 2012
Renaud L. Does Acetylation Regulate microRNA Expression in Myocardial
Infarction? Department of Medicine Research Day, January 2012, MUSC.
115
Menick DR, Li MS, Renaud L, Chernysh O, Mani SK. “HDAC1/2 and HDAC5 have
Distinct Roles in the Deacetylation of Nkx2.5 and the Upregulation of Sodium Calcium
Exchanger Expression in Cardiac Hypertrophy”. International Society for Heart
Research, North American Section, Banff, Canada 2012, to be published in Journal of
Molecular and Cellular Cardiology.
Renaud L, Kasiganesan H, Gao E, Mani SK, Jones JA, Stroud RE, J, Menick DR.
“Regulation of miR-21 Expression by Acetylation in Myocardial Infarction”.
Sent to AHA-BCVS 2012 Scientific Sessions 2012 to be published in special issue of
Circulation Research.
46TH Annual Perry V. Halushka MUSC Student Research Day, November 4, 2011.
Wilkerson BA, Grass GD, Wing SB, Argraves WS, Argraves KM. S1P carrier-dependent
regulation of endothelial barrier: HDL-S1P prolongs endothelial barrier enhancement as
compared to albumin-S1P via effects on levels, trafficking and signaling of S1P1. 46TH
Annual Perry V. Halushka MUSC Student Research Day; November 4, 2011.
Zhang X, Yu H, D'Silva NJ, Kirkwood KL. MKP-1 deficiency enhances murine oral
neoplasia at the Keystone Symposia: The Role of Inflammation in Carcinogenesis,
Dublin, Ireland, May 2012
STUDENTS’ HONORS AND AWARDS
Allen, Emily
SGA Representative of the Year 2011-2012
Al Sarraf, Oday
Presidential Scholar Inductee
Student Leadership Society Award and Inductee
MUSC Chess Society Founding Member
Treasurer, Graduate Student Association
MUSC Student Research Day Improvement Committee, Nov 2011
Winner of 2012 “Mr. MUSC” Interprofessional Talent Competition
South Carolina Representative for World Glaucoma Week
MUSC Ethics Committee Active Member
MUSC Ethics Consults Services Active Member
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Charles H. Banov Humanitarian Award Nominee
Briggs, Laura
Travel Award to 2012 Weinstein Conference
Corum, Daniel
NHLBI Training Grant (T32) “Training to Improve Cardiovascular Therapies”
Recipient, Pre-Doctoral Fellow, August 2012-July 2013.
Czajka, Caitlin
Cribben, Kathryn
Mid-Atlantic Affiliate Winter 2012 Predoctoral Fellowship American Heart Association.
Second Place, Ph.D. II Poster Presentation, Perry V. Halushka Student Research Day,
MUSC, November 2012
Honorable Mention, Awarded by Ralph H. Johnson VA Medical Center, Perry V.
Halushka Student Research Day, MUSC, 2012
Dahrouj, Mohammad
Travel Grant Award for ARVO 2012,
Foundation/Joseph M. and Eula C. Lawrence
ARVO
Foundation/Retina
Research
Gentile, Carmine
AHA predoctoral grant 07/01/11-06/30/13 11PRE7530048 (Gentile). VEGF/Aktmediated Endothelial Nitric Oxide Synthase Phosphorylation as a Regulator of
Endothelial Cell Division
Grass, Daniel
ASCI (American Society for Clinical Investigation), AAP (Association of American
Physicians) Joint Meeting Travel Award. Chicago, IL. For abstract “EMMPRIN (CD147)
is a Novel Regulator of Invadopodia Formation and Activity.”
1st Place Recipient, PhD III Poster Category: Perry V. Halushka Student Research Day
2011 MUSC
Kimbrough, Denise
Cardiovascular Outreach Award, at the Basic Cardiovascular Sciences 2012 Scientific
Sessions.
117
Lindner, Haley (Amanda)
First Place Oral Presentation for Veterans Affairs (Student Research Day 2011)
First Place Oral Presentation PhD VII (Student Research Day 2011) (Willard & Betty
Peterson Award)
Third Place Poster presentation CDM Scholars Day (February 2012)
Selected as Young Investigators Award Winner (Wound Healing Society, Atlanta 2012)
Received F30 (began in July 2011)
Lockhart, Marie
American Heart Association Pre-Doctoral Grant ($46,000). *Funding starts July 2012*
Moseley, Vondina
2011 AACR Minority Scholar in Cancer Research
AACR High School Program Mentor
Pleasant, Dorea
Recipient, Pre-Doctoral Fellow, September 2011-Present.
Renaud, Ludivine
1st Place Winner for MUSC Student Research Day 2011 for Oral Presentation
PhD V.
Trombetta-eSilva, Jessica
Impact/Priority Score of 17 on F30 Individual Fellowship Application, F30
Individual Fellowship Awarded
Wheeler, Jason
1st Place Winner for MUSC Student Research Day 2011, Clinical-ProfessionalMasters Oral V
2nd Place Winner for MUSC Student Research Day 2011, Health Disparities Oral
Presentation.
Zhang, Xiaoyi
American Medical Association Foundation 2012 Seed Grant Recipient. The role of
mitogen-activated protein kinase phosphatase-1 in tumor progression.
MKP-1 deficiency enhances murine oral neoplasia at the MUSC 10th Annual Head and
Neck Multidisciplinary Research Workshop, Charleston, SC, April 2012; 1st place
118
MKP-1 deficiency enhances epithelial neoplasia in a murine oral cancer model at the
MUSC Perry V. Halushka Student Research Day, Charleston, SC, November 2011; 2nd
place in the PhD IV Oral Presentation category.
This has been another outstanding year for the students in the MCBP Program. This
year our students published/submitted 29 manuscripts, many in high-impact journals,
including The Journal of Biological Chemistry, Oncogene, and The EMBO Journal. In
addition to the manuscripts, our students have presented 73 abstracts at local, national,
and international meetings. Our student’s work has been honored with an impressive
number of highly competitive local, national, and international local awards and
fellowships. Carmine Gentile, Marie Lockhart and Kathryn Cribben have received predoctoral fellowships from the American Heart Association (AHA). Jessica TrombettaeSilva was awarded an individual NIH Ruth L. Kirschstein National Research
Fellowship. Four of our students, Kathryn Cribben, Caitlin Czajka, Dorea Pleasant, and
Denise Kimbrough received NIH T-32 Training Fellowships, “NIH Training to Improve
Cardiovascular Therapies”. Daniel Grass, Haley (Amanda) Lindner, Ludivine Renaud
and Jason Wheeler received 1st place awards for their presentations in the MUSC
“Perry V. Halushka 2011 Student Research Day”. Kathryn Cribben, Jason Wheeler and
Yiaoyi “Tina” Zhang all received 2nd place awards in the MUSC 2011 “Perry V. Halushka
Student Research Day”. Haley (Amanda) Lindner was also honored with a 1st place
award for her presentation from the Ralph H. Johnson VA Medical Center. Many of our
students have been honored by Travel Awards to both national and international
meetings, and have been recognized with awards for their poster and/or oral
presentations at some of those meetings. Lastly, 9 of our students graduated from
MUSC on May 18, 2012; 6 received a Ph.D. degree, and 3 received both the MD &
Ph.D degrees (Medical Scientist Training Program) (MSTP). Thomas Mullen (MSTP)
was honored as a “Distinguished Graduate Student Award finalist, and received his
degrees with honors. These graduates are moving on to post-doctoral training positions
and internships in some of the best laboratories and institutions in the country. All of the
students in the MCBP Program have done well and we are very proud of their
accomplishments.
The MCBP Graduate Program provides a rich and diverse training environment for
students, allowing for multi-disciplinary projects that can easily span the traditional
areas of molecular biology, cell biology, pharmacology and physiology. One of the
greatest challenges we continue to have in this time of increased difficulty in getting and
maintaining extramural support for our research efforts is preventing the erosion of the
quality of teaching and academic excellence. We are undergoing a concerted effort to
maintain and even increase the number of advanced courses that are being offered to
our students. Our commitment is to making the MCBP Program the best possible
training environment for our students. To this end our goals for the next year are to
119
ensure that the many MCBP advanced graduate courses including new courses are
offered on a regular basis. This year the MCBP progress committee is also
reexamining the MCBP written Qualifying Exam to insure that it serves to prepare our
student to succeed and compete for the best post-doctorial fellowships and academic
positions. We will work to insure that the journal clubs which have been established in
many of the divisions are continued and new journal clubs established in those that do
not have them, be more informative to students inquiring about the program as well as
our own students who are currently in the program, and to re-double our efforts to giving
our students the best training and preparation possible for a fulfilling career in
biomedical research.
120
SUMMER HEALTH PROFESSIONALS RESEARCH PROGRAM
2011-2012
The objectives of the program are: (1) to attract highly motivated and qualified students
into careers in biomedical research; (2) to provide an increased awareness of research
methods and results to practicing health professionals; and (3) to further stimulate the
interaction between the clinical services and the research programs at this university.
Students In The Program In The Summer Of 2011:
Student’s Name
Matriculation
Mentor
Date
Abro, Joseph A
10/FA
Uwe O.P. Joseph Schoepf, MD
Ambrose, Andrew*
10/FA
Walter G. Renne, DMD
Arana, Ashley B.*
10/FA
Francis G. Spinale, MD, PhD
Ashley, Bryan E.
10/FA
Leonard Egede, MD, MS
Baldwin, Chelsey K.
10/FA
Aquilla S. Turk, DO
Biggs, Caitlin M.
10/FA
Michael J. Kern, PhD
Bloomquist, Geoffrey
10/FA
Caroline Westwater, PhD
Bomar, Paul A.
10/FA
Christopher Parsons, MD
Bouges, Shenikqua*
10/FA
Brown, Satara*
10/FA
Terrence X. O’Brien, MD, MS
Bryant, Robert C.*
10/FA
Daniel Lackland, PhD
Davis, Tabatha B.
10/FA
Maria Buse, MD
Desai, Shivam
10/FA
Qian Kang, MD
Desjardins, Danielle
10/FA
Craig C. Beeson, PhD
DeWeerth, Jacob C.
10/FA
Doshi, Tejas M.
10/FA
Lauren E. Ball, PhD
Ezenekwe, Chisom*
10/FA
Fox, Adam H.
10/FA
Hanna, Evan L.
10/FA
Uwe O.P. Joseph Schoepf, MD
Iyer, Arun M.
10/FA
Phillip Darwin Bell, PhD
Johnson, Benton L.
10/FA
Steven W. Kubalak, PhD
Joyner, Alisha*
10/FA
Sonya D. Coaxum, PhD
LeBel, David P.
10/FA
Titus A. Reaves, PhD
Lovelace, Tiffany L.
10/FA
Terrence A. Day, MD
Lumpkin, Jeanne B.
10/FA
McConnell, Amy E.
10/FA
Susan G. Reed, DDS, DrPH
McMillin, Jake C.
10/FA
Craig E. Crosson, PhD
McNeill, Stephanie*
10/FA
Miller, Thomas E.*
10/FA
Moore, Charles L.
10/FA
Obi, Okwuchukwu*
10/FA
Narendra L. Banik
Paige, Jennifer N.*
10/FA
Melissa Howard Henshaw, MD
Reid, Jamaeka N.*
10/FA
Romero, Katalina*
10/FA
Maria F. Lopes-Virella, MD,
PhD
121
Degree
Sought
MD
DMD
MD
MD
MD
DMD
DMD
MD
MD
MD
MD
MD
MD
MD
MD
MD
MD
MD
MD
MD
MD
MD
MD
DMD
MD
DMD
MD
MD
MD
DMD
MD
MD
MD
MD
Seabrook, Nelson E.
Simmons, Flora M. *
Smith, Christopher *
Smith, Sara C.
Stokes, William A.
Teuber, Julie M.
Tholanikunnel, Tracy
Topiwala, Pritesh
Villar, Juan Jose*
Williams, Karla E.*
Winchester, Rhonda
Yazdy, Golsa M.
*URM Participants
10/FA
10/FA
10/FA
10/FA
10/FA
10/FA
10/FA
10/FA
10/FA
10/FA
10/FA
10/FA
Pal Suranyi, MD, PhD
George Cooper, IV, MD
Donald R. Menick, PhD
Kenneth Chavin, MD, PhD
Yan Huang, MD, PhD
Eleanor K. Spicer, PhD
Zoran Rumboldt, MD
Kenneth Chavin, MD, PhD
Oluwatosin Jaiyeoba, MD
MD
MD
MD
MD
MD
MD
MD
MD
MD
MD
MD
MD
Publications:
Arnoldi E, Ramos-Duran I, Abro JA, Zwerner PL, Nikolaou K, Reiser MF, Costello P,
Schoepf UJ. [Coronary CT angiography using prospective ECG triggering: high
diagnostic accuracy with low radiation dose]. Radiologe. 2010 Jun;50(6):500-6.
German. PubMed PMID: 20390243
Bastarrika G, Ramos-Duran L, Schoepf UJ, Rosenblum MA, Abro JA, Brothers RL,
Zubieta JL, Chiaramida SA, Kang DK. Adenosine-stress dynamic myocardial volume
perfusion imaging with second generation dual-source computed tomography: Concepts
and first experiences. J Cardiovasc Comput Tomogr. 2010 Mar-Apr;4(2):127-35. Epub
2010 Jan 28. PubMed PMID: 20430344
Bastarrika G, Kang DK, Abro JA, Schoepf UJ. [Comprehensive assessment of
coronary disease using perfusion CT with pharmacologically induced stress].
Radiologia. 2010 Sep-Oct;52(5):469-72. Epub 2010 May 18. Spanish. PubMed PMID:
20483440
Kang DK, Ramos-Duran L, Schoepf UJ, Armstrong AM, Abro JA, Ravenel JG, Thilo C.
Reproducibility of CT signs of right ventricular dysfunction in acute pulmonary
embolism. AJR Am J Roentgenol. 2010 Jun;194(6):1500-6. PubMed PMID:20489089
Kang DK, Schoepf UJ, Bastarrika G, Nance JW Jr, Abro JA, Ruzsics B. Dual-energy
computed tomography for integrative imaging of coronary artery disease: principles and
clinical applications. Semin Ultrasound CT MR. 2010 Aug;31(4):276-91. Review.
PubMed PMID: 20691928
Henzler T, Barraza JM Jr, Nance JW Jr, Costello P, Krissak R, Fink C, Schoepf UJ. CT
imaging of acute pulmonary embolism. J Cardiovasc Comput Tomogr. 2011 JanFeb;5(1):3-11. Epub 2010 Oct 29. Review. PubMed PMID: 21051309
122
Weininger M, Renker M, Rowe GW, Abro JA, Costello P, Schoepf UJ. Integrative
computed tomographic imaging of coronary artery disease. Expert Rev Cardiovasc
Ther. 2011 Jan;9(1):27-43. Review. PubMed PMID: 21166527
Weininger M, Schoepf UJ, Ramachandra A, Fink C, Rowe GW, Costello P, Henzler T.
Adenosine-stress dynamic real-time myocardial perfusion CT and adenosine-stress
first-pass dual-energy myocardial perfusion CT for the assessment of acute chest pain:
Initial results. Eur J Radiol. 2010 Dec 29. [Epub ahead of print] PubMed PMID:
21194865
Nance JW Jr, Bastarrika G, Kang DK, Ruzsics B, Vogt S, Schmidt B, Raupach R, Flohr
TG, Schoepf UJ. High-temporal resolution dual-energy computed tomography of the
heart using a novel hybrid image reconstruction algorithm: initial experience. J Comput
Assist Tomogr. 2011 Jan-Feb;35(1):119-25. PubMed PMID: 21245697
Blackmon KN, Florin C, Bogoni L, McCain JW, Koonce JD, Lee H, Bastarrika G, Thilo
C, Costello P, Salganicoff M, Schoepf UJ. Computer-aided detection of pulmonary
embolism at CT pulmonary angiography: can it improve performance of inexperienced
readers? Eur Radiol. 2011 Jun;21(6):1214-23. Epub 2011 Jan 13. PubMed PMID:
21225269
Huda W, Schoepf UJ, Abro JA, Mah E, Costello P. Radiation-related cancer risks in a
clinical patient population undergoing cardiac CT. AJR Am J Roentgenol. 2011
Feb;196(2):W159-65. PubMed PMID: 21257857
Meyer M, Nance JW Jr, Schoepf UJ, Moscariello A, Weininger M, Rowe GW, Ruzsics
B, Kang DK, Chiaramida SA, Schoenberg SO, Fink C, Henzler T. Cost-effectiveness of
substituting dual-energy CT for SPECT in the assessment of myocardial perfusion for
the workup of coronary artery disease. Eur J Radiol. 2011 Jan 27. [Epub ahead of print]
PubMed PMID: 21277132
Weininger M, Barraza JM, Kemper CA, Kalafut JF, Costello P, Schoepf UJ.
Cardiothoracic CT angiography: current contrast medium delivery strategies. AJR Am J
Roentgenol. 2011 Mar;196(3):W260-72. Review. PubMed PMID: 21343473
Fink C, Krissak R, Henzler T, Lechel U, Brix G, Takx RA, Nance JW, Abro JA,
Schoenberg SO, Schoepf UJ. Radiation dose at coronary CT angiography: secondgeneration dual-source CT versus single-source 64-MDCT and first-generation dualsource CT. AJR Am J Roentgenol. 2011 May;196(5):W550-7. PubMed PMID: 21512044
Nance JW Jr, Kratz JM, Ikonomidis JS, Toole JM, Barraza JM, McMaster WG,
Schoepf UJ. Apicoaortic Conduits, an innovative solution to difficult aortic stenosis: the
MUSC Experience. J S C Med Assoc. 2011 Aug;107(4):160-3. PubMed PMID:
22057751
123
Student Presentations
Poster
Treatment of Cerebral Aneurysms: Does Size Matter? Chelsey K Baldwin1, Aquilla
Turk2; 1College of Medicine, MUSC, 2Neuro-interventional/Radiology, MUSC. 2011
Perry V. Halushka MUSC Student Research Day, Winner – 1st Place (session 4)
Examination of the Role of HuR in the Post-Transcriptional Regulation of Nucleolin
Expression in Breast Cancer Cells, Tracy Tholanikunnel1, Sudeep Bose2, Eleanor
Spicer3; 1Medicine, MUSC, 2Regenerative Medicine and Cell Biology, MUSC,
3Biochemistry and Molecular Biology, MUSC. 2011 Perry V. Halushka MUSC Student
Research Day, Winner – 2nd Place (session 5)
Management of Hypertension At a Free Clinic and Emergency Department, Thomas E
Miller III, Daniel Lackland; Neurosciences, MUSC. 2011 Perry V. Halushka MUSC
Effect of Locus of Control on Clinical Outcomes for Diabetes, Bryan E Ashley, Melba A
Hernandez-Tejada, Joni L Strom, Leonard E Egede; Medicine, MUSC. 2011 Perry V.
Glycemic Control In VA Clinical Sites Compared To Non VA Sites Among Adults With
Type 2 Diabetes, Jeanne B Lumpkin, Clara E Dismuke, Joni L Strom, Leonard E
Egede; Medicine, MUSC. 2011 Perry V. Halushka MUSC Student Research Day
Ethnic Differences in Control of Multiple Diabetes Risk Outcomes, Jamaeka N Reid,
Cheryl P Lynch, Joni L Strom, Leonard E Egede; Medicine, MUSC . 2011 Perry V.
Gender Differences in Composite Control of Cardiovascular Risk Factors, Rhonda
Winchester, Cheryl P Lynch, Joni L Strom, Leonard E Egede; Medicine, MUSC. 2011
Perry V. Halushka MUSC Student Research Day
Effect of Spirituality on Multiple Diabetes Outcomes, Chisom Ezenekwe, Melba A
Hernandez-Tejada, Joni L Strom, Leonard E Egede; Medicine, MUSC. 2011 Perry V.
Free Clinic Vs Emergency Department Population Management of Diabetes Mellitus
Types II: A Retrospective Study, Robert Bryant1, Daniel Lackland2, Michael Saef3;
1Medicine, MUSC, 2Epidemiology, MUSC, 3Emergency, MUSC. 2011 Perry V.
Perifocal Diffusion Values in Assessing Prognosis of Brain Gliomas, Pritesh
Topiwala1, Vittoria M Spampinato2, Zoran Rumboldt2; 1Radiology, MUSC,
2Neuroradiology, MUSC. 2011 Perry V. Halushka MUSC Student Research Day
124
Prevalence and Predictors of Sleep Disorders in an Adult Sample with Type 2 Diabetes.
Golsa Yazdy, Sujeev S Bains, Joni L Strom, L E Egede; Medicine, MUSC. 2011 Perry
V. Halushka MUSC Student Research Day
Effect Of Trust In Health Care Providers On Multiple Diabetes Outcomes, S Bouges, C
P Lynch, J L Strom, L E Egede; Health Disparities Research, MUSC. 2011 Perry V.
The Role of the Tongue in Secondary Palate Elevation of Prrx1 Deficient Mice, Caitlin
M Biggs1,Michael J Kern2; 1Dental Medicine, MUSC, 2Regenerative Medicine and Cell
Biology, MUSC. 2011 Perry V. Halushka MUSC Student Research Day
Effects of TGF-Beta on NIH-3T3 Cell Proliferation, Migration, and Apoptosis, Benton L
Johnson1, Steven W Kubalak2, Jayne Bernanke2; 1Medicine, MUSC, 2Regenerative
Medicine and Cell Biology, MUSC. 2011 Perry V. Halushka MUSC Student Research
Day
The Varied Effect of NAC and Cocoa on LPS Stimulated IL-6 Release By Both
Mononuclear Cells and Human Gingiva Fibroblasts, William A Stokes1, Yan Huang2;
1
Medicine, MUSC, 2Endocrinology, MUSC. 2011 Perry V. Halushka MUSC Student
Research Day
The Prevalence and Clinical Significance of Mycoplasma Genitalium in Our Gynecologic
Patients: A Preliminary Review, Karla E Williams, Oluwatosin Jaiyeoba, David E
Soper; Obstetrics and Gynecology, MUSC. 2011 Perry V. Halushka MUSC Student
Research Day
Connexin 40 Remodeling in Purkinje Cardiomyocytes Post-Myocardial Infarction,
Satara A Brown1, Mary S Rackley2, Brett S Harris3, Terrence X O'Brien2; 1Medicine,
MUSC, 2Cardiology, MUSC; Medicine, VAMC, 3Regenerative Medicine and Cell Biology,
MUSC. 2011 Perry V. Halushka MUSC Student Research Day
Unanticipated Effects of Adenosine on Microtubule Density, Flora M Simmons, Grace
Wallenborn, George Cooper; Medicine, MUSC. 2011 Perry V. Halushka MUSC Student
Research Day
The Pitfalls of Automated Functional Analysis in Cardiac CT, Nelson E Seabrook, Pal
Suranyi; Radiology, MUSC. 2011 Perry V. Halushka MUSC Student Research Day
Generation of a Novel Bacteriostatic and Anti-collagenolytic Dental Adhesive Through
the Incorporation of Polyacrylic Acid Modified Copper Nanoparticles Into Adhesive
Resins, Andrew W Ambrose1, Walter Renne1, Michael Schmidt2; 1Restorative
Dentistry, MUSC, 2Microbiology, MUSC. 2011 Perry V. Halushka MUSC Student
Research Day
125
Oral Presentations
Prevalence of Vitamin D Deficiency in Obese Children and Adolescents, Jennifer N
Paige, Janet Carter, Melissa Henshaw; Medicine, MUSC. 2011 Perry V. Halushka
MUSC Student Research Day. Winner – 1st place (session 16)
Interstitial Trafficking of MicroRNAs Within the Human Myocardium Following IschemiaReperfusion, Ashley B Arana, Robert E Stroud, Risha Patel, Jeffery Jones, Francis G
Spinale; Cardiothoracic Surgery, MUSC2011 Perry V. Halushka MUSC Student
Research Day. Winner – 2nd place (session 16)
Predictors of Adequate Health Literacy In a Diverse Primary Care Sample with Type 2
Diabetes, Julie Teuber, Sujeev S Bains, Joni L Strom, L E Egede; Medicine, MUSC.
2011 Perry V. Halushka MUSC Student Research Day
Multiple Cardiovascular Risk Factor Control (MCRFC) Across Sites of Care in Type 2
Diabetes, Jacob C DeWeerth, Clara E Dismuke, Joni L Strom, Leonard E Egede;
Medicine, MUSC. 2011 Perry V. Halushka MUSC Student Research Day
Effect Of Delayed Discounting On Multiple Diabetes Outcomes In Adults With Diabetes,
Adam H Fox, Clara E Dismuke, Joni L Strom, Leonard E Egede; Medicine, MUSC.
Is Cirrhosis a Contraindication to Laparoscopic Cholecystectomy? Juan José E VillarBenavides, McGillicuddy, Sapna Bazaz, David J Taber, Nicole A Weimert, Prabhakar
Baliga, Kenneth D Chavin; Transplant Surgery, MUSC. 2011 Perry V. Halushka MUSC
The Role of Complement Peptides, C3a, in Host Defense Against Candida, a Human
Fungal Pathogen, Geoff Bloomquist1, Caroline Westwater2; 1College of Dental
Medicine, MUSC, 2Craniofacial Biology, MUSC. 2011 Perry V. Halushka MUSC Student
Research Day
Melatonin Attenuates Oligodendrocyte Cell Death and Myelin Loss, Okwuchukwu G
Obi1, Arabinda Das2, Narendra L Banik2; 1Medicine, MUSC, 2Neuroscience, MUSC.
The Role of the Prrx-1 Gene in Cell Proliferation During Secondary Palate
Development, Charles Moore1, Michael Kern2, Christine Kern2; 1Dental Medicine,
MUSC, 2Regenerative Medicine and Cell Biology, MUSC. 2011 Perry V. Halushka
MUSC Student Research Day
Expression of Nucleobindin-2/Nesfatin-1 in Bone Tissue, Tejas Doshi1, Lauren Ball1,
Alexis Nagel2; 1Pharmacology, MUSC, 2Pharmacology, MUSC. 2011 Perry V. Halushka
MUSC Student Research Day
126
Mitochondrial Dysfunction in Degenerative Pathologies, Danielle M Desjardins1, Craig
Cano Beeson2; 1College of Graduate Studies, MUSC, 2College of Pharmacy /
Pharmaceutical & Biomedical Sciences, MUSC. 2011 Perry V. Halushka MUSC Student
Research Day
The Effect of IRS-1 Modification By N-acetyl Glucosamine (O-GlcNAc) on the Insulin
Response, Tabatha B Davis1, Katherine Robinson1, Maria G Buse1, Lauren Ball2;
1
Endocrinology, MUSC, 2Pharmacology, MUSC. 2011 Perry V. Halushka MUSC
Computed Tomography, Shane Oberoi, U Joseph Schoepf, John Nance; Radiology,
MUSC. 2011 Perry V. Halushka MUSC Student Research Day
Radiation Dose and Image Quality At High-Speed CT Angiography of the Aorta: IntraIndividual and Inter-Individual Comparison with Conventional CT Angiography, E
Lexworth Hanna1, Paul Apfaltrer1, J. Reid Spears1, Garrett W Rowe1, Daniel Harris1,
Stefan O Schoenberg2, Rozemarijn Vliegenthart1, U Joseph Schoepf1; 1Radiology,
MUSC, 2Clinical Radiology and Nuclear Medicine, University Medical Center
Mannheim. . 2011 Perry V. Halushka MUSC Student Research Day
Stimulation of Human Aortic Endothelial Cells (HAEC) with OxLDL-IC Stimulates Fc
Gamma Receptor Expression and Endothelial Dysfunction, Katalina Romero1,
Yanchun F Li2, Gabriel Virella3, Maria Lopes-Virella2; 1Medicine, MUSC, 2Endocrinology,
Diabetes & Medical Genetics, MUSC, 3Microbiology & Immunology, MUSC. 2011 Perry
V. Halushka MUSC Student Research Day
Kaposi’s Sarcoma-Associated Herpesvirus Induced Expression Of Emmprin On The
Cell Surface Following De Novo Infection Of Endothelial Cells, Paul A Bomar,
Christopher Parsons; Infectious Disease, MUSC. 2011 Perry V. Halushka MUSC
127
The objectives of the program are to introduce students to biomedical research, to
acquaint them with opportunities here at the Medical University of South Carolina and,
hopefully, to induce them to apply for admission. In addition to laboratory research
experiences, the students participate in a weekly seminar series to expose them to the
wide range of research being addressed by the Medical University of South Carolina
faculty. Students presented the results of their research projects in final sessions in
August. The students and participating faculty are requested to evaluate and criticize
the strengths and weaknesses of the summer internship. Since its inception more than
1107 students have participated in the program. Of these, 988 have received course
credit for the program and 213 have gone on to enroll in our University. Again this year,
over 4,000 information packets were mailed to colleges and universities throughout the
U.S. E-mails were sent to health sciences advisors throughout the U.S. E-mails were
also sent to program advisors around the country for the MARC, Meyerhoff, McNair and
RISE programs. For the Summer 2011 program, we received 381 applications, and 65
students participated in the program. Of the sixty-five students who participated, 33
were underrepresented minority students. Funding for the program was provided
through training grants from the National Institutes of Health (NIH) which supported 16
minority students, the DOD which supported 6 minority students, Liberty Life Insurance
which supported 2 minority students, the Clinical and Translational Science Award
which supported 5 students, Palmetto Academy which supported 3 students, Morris
College which supported 2 students, the College of Dental Medicine which supported 1
student, MUSC Faculty, Departments and the College of Graduate Studies supported
30 students.
Home College/University
Academic Magnet HS (1)
Baylor University (1)
Claflin University (4)
Clemson University (14)
College of Charleston (12)
Cornell College (1)
Duke University (1)
Eastman School of Music (1)
Erskine College (1)
Florida International University (1)
Furman University (1)
Georgia Institute of Technology (1)
Hampton University (1)
Inter-American Univ of P.R. (1)
King’s College (1)
Morris College (2)
Presbyterian College (1)
Providence College (1)
Queens Univ. of Charlotte (1)
South Carolina State Univ. (4)
Spelman College (2)
The Ohio State Univ. (1)
University of Florida (1)
Univ. of Maryland, Baltimore County (1)
University of the South (1)
Voorhees College (2)
Washington & Lee University (1)
Washington Univ. in St. Louis (1)
Winthrop University (1)
Wofford College (2)
128
Research Interests Selected
Biochemistry (4)
Bioengineering (1)
Bioinformatics/Epidemiology (3)
Cancer Biology (8)
Cardiovascular Biology (7)
Cell & Molecular Biology (1)
Craniofacial Biology (1)
Developmental Biology (1)
Genetics & Development (1)
Translational Research (3)
Health Disparities (6)
Marine Biomedicine (1)
Microbiology & Immunology (5)
Neurosciences (9)
Pathology & Laboratory Medicine (1)
Pharmaceutical Sciences (3)
Proteomics (1)
Space-Related Life Sciences/NASA (4)
Regenerative Medicine (2)
Honors, Awards & Publications:
Cartmell, Kathleen B.; Miner, Christine; Carpenter, Matthew J.; Vrroc, Camelia S.;
Biggers; Onicescu, Georgiana; Hill, Elizabeth; Nickerson, Brenda C.; Alberg, Anthony.
Secondhand Smoke Exposure in Young People and Parental Rules Against Smoking at
Home and in the Car. Public Health Reports, Volume 126, July-August 2011
McDonald W, Durkalski V, Ball E et al "Improving the antidepressant efficacy of
transcranial magnetic stimulation: Maximizing the number of stimulations and treatment
location in treatment resistant depression." Depress Anxiety. 2011 Sep 2. (PMID:
21898711)
L. Dupuis, D. R. McCulloch, J.D. McGarity, A. Bahn, A. Wessels, D. Weber, A. Megan
Diminich, C.M. Nelson, S. S. Apte, C.B. Kern. Altered versican cleavage in ADAMTS5
deficient mice: A novel etiology of myxomatous valve disease. Developmental Biology
Dev Biol. 2011 Sep 1;357(1):152-64.
Dunmyer J, Hudson C, West L, Carpenter B, Leite RS. Hollywood Smiles – A CBPR
Approach to Evaluate and Address the Oral Health Needs of the Gullah Population
Living in Hollywood, SC. MUSC 2011 Black History Month Lecture Series “Dialogue on
Health Care Disparities Featuring the Research of MUSCs Black Student Scholars.”
Charleston, SC. February, 2011.
Hudson C, West L, Carpenter E, Leite RS. Hollywood Smiles Handbook. 46th Annual
Perry V. Halushka MUSC 2011 Student Research Day. Charleston, SC. November
4th, 2011.
Westerkam D. (2010 undergraduate) – published September 2011. Westerkam, D.,
Saunders, L.L., & Krause, J.S. (2011). Association of spasticity and life satisfaction after
spinal cord injury. Spinal Cord, 49, 990-994.
129
Poster Presentations:
The Effects of Beta-arrestin 1 and 2 Overexpression on TLR-induced Inflammatory
Cytokine Expression in RAW 264.7, Rocky C Wong1, Hongkuan Fan2, Perry
Halushka2, James Cook2, Sarah Ashton2,, Peifeng Li2; 1CofC, 2Neuroscience, MUSC.
2011 Perry V. Halushka MUSC Student Research Day.
Retinyl Ester Accumulation in the Absence of Light, Colleen K Sheridan1, Yiannis
Koutalos2; 1Biology, CofC, 2Ophthalmology, MUSC. 2011 Perry V. Halushka MUSC
Student Research Day. 2nd Place Award
Determining the Variability in Developing Post-Stroke Pneumonia, Gabriela R Keeton,
Daniel T Lackland; Neurosciences, MUSC. 2011 Perry V. Halushka MUSC Student
Research Day.
Generation of Nicotinamide Adenine Dinucleotide Phosphate (NADPH) in Vertebrate
Photoreceptors, Leopold Adler IV1, Yiannis Koutalos2, Chunhe Chen2; 1Physics and
Astronomy, CofC, 2Ophthalmology, MUSC. 2011 Perry V. Halushka MUSC Student
Research Day.
Modafinil Reverses Methamphetamine-Induced Memory Deficits On An Object-In-Place
Task In Rats: Role Of Glutamate Receptor Expression, Meghin J Gilstrap1, Carmela M
Reichel2, Lauren A Ramsey3, Jackie F McGinty2, Ron E See2;
1Psychology/Neuroscience, CofC, 2Neurosciences, MUSC, 3Biology, CofC. 2011 Perry
V. Halushka MUSC Student Research Day. 1st Place Award
Novel Targets of Nkx2.5 Regulation in the Second Heart Field, Anthony J Horton, KyuHo Lee; Regenerative Medicine and Cell Biology, MUSC. 2011 Perry V. Halushka
MUSC Student Research Day.
In the ADAMTS5 Mouse Model of Myxomatous Valve Disease Increased Proteoglycans
Contribute to Disease Progression, Kelsha M. Washington1, Loren E. Dupuis2, Marion
A. Cooley2, W. Scott Argraves2, Christine B. Kern2; 1Claflin University, 2Regenerative
Medicine and Cell Biology. 2011 Perry V. Halushka MUSC Student Research Day.
Effects of a Connexin43 Mimetic Peptide on Myocyte-Fibroblast Adhesion in a 3D
Model of Cardiac Injury, Hina Siddiqui1, Emily L Ongstad2, Robert G Gourdie2;
1Biology, College of Charleston, 2Regenerative Medicine and Cell Biology, MUSC.
Space Flight Causes Transcriptomic Changes in the Small Intestine Affecting Nutrition
and Digestion, Max N Hughes1, Scott W Argraves2, Jeremy L Barth2; 1Clemson
University, 2Regenerative Medicine and Cell Biology, MUSC. 2011 Perry V. Halushka
130
The Effect of Fingolimod (FTY720) on Small Cell Lung Cancer and Non-Small Cell Lung
Cancer, Jessica S Creel1, Sahar Saddoughi2, Besim Ogretmen2; 1Chemistry,
Winthrop University, 2Biochemistry & Molecular Biology, MUSC. 2011 Perry V.
Halushka MUSC Student Research Day. 2nd Place Award
Association of Willingness to Participate in Research Studies with Payment, Risk, and
Time Among Individuals with Type 2 Diabetes, Kimberly T Arnold1, Leonard Egede2,
Clara L Dismuke3, Joni Strom2; 1CofC, 2Health Disparities, MUSC, 3VAMC. 2011
Perry V. Halushka MUSC Student Research Day. 1st Place Award
Velcade and Organ Transplant Desensitization, Emma M Bradley, Omar Moussa,
Yuan Shao; Pathology and Laboratory Medicine, MUSC. 2011 Perry V. Halushka
Attitudes and Knowledge of Atrial Fibrillation Treatment and Stroke Prevention, Andrew
B Gundran1, Daniel T Lackland2; 1Psychology, Clemson, 2Neuroscience, MUSC.
Oral Presentations
Nkx2.5 Regulates Hoxb4, MiR-10a, and Jarid2 Expression in the Developing Heart,
Aaron M Blackshaw1, Kyu-Ho Lee2; 1CofC, 2MUSC Pediatric Cardiology. 2011 Perry
V. Halushka MUSC Student Research Day. 1st Place Oral Award
Comparative Transcriptome Analysis to Identify Genes Regulating Elastogenesis,
Sharon L Guffy1, Erin L Pardue1, Jeremy L Barth1, Kathleen R Braun 2, Thomas N
Wight2, W Scott Argraves1; 1Regenerative Medicine and Cell Biology, MUSC,
2Benaroya Research Institute. 2011 Perry V. Halushka MUSC Student Research Day.
2nd Place Oral Award
The Effect of Cytokines on T Cell Antioxidant Capacity, Jazzmine Clemons1, Shikhar
Mehrotra2; 1Claflin University (SURP), 2MUSC2011 Perry V. Halushka MUSC Student
Research Day.
MBD4 DNA Repair in Prostate Cancer, Sierra S. Brooks1, David Turner2; 1Voorhees
College, 2MUSC. 2011 Perry V. Halushka MUSC Student Research Day.
Thioredoxin 1 As a Therapeutic Target in Advanced Prostate Cancer, DeAngelo
Dinkins1, Christina Voelkel-Johnson2; 1SC State University, 2MUSC. 2011 Perry V.
Halushka MUSC Student Research Day.
Anxiogenic Effects of Cocaine Withdrawal in Rats, Kyle T Brown, Parrish R Waters,
Ronald E See; Psychology, CofC. 2011 Perry V. Halushka MUSC Student Research
Day.
131
Structure-function Relationships in the Brain Using Imaging Across Multiple Spatial
Scales, Grace Margaret A Dion, Zhongyang Lu, Manuel Levy, Prakash Kara;
Neuroscience, MUSC. 2011 Perry V. Halushka MUSC Student Research Day.
Evaluating an Intervention to Increase Cancer Knowledge in Racially Diverse
Communities in South Carolina, CoDanielle Green1, Marvella E. Ford2; 1SC State
University, 2MUSC. 2011 Perry V. Halushka MUSC Student Research Day.
Using a Community-Based Participatory Research Approach to Create and Test a
Culturally Sensitive Oral Health Educational Handbook-Hollywood Smiles Handbook,
Christine M Hudson1, Lynn J West1, Elizabeth Carpenter2, Renata Leite1; 1Center for
Oral Health Research, MUSC, 2Hollywood, SC, Mayor's Office. 2011 Perry V. Halushka
132
Governor’s School for Science & Mathematics
Summer Program for Research Interns (SPRI)
The Summer Program for Research Interns (SPRI) is a program coordinated through
the South Carolina Governor’s School for Science and Mathematics (GSSM) for rising
high school seniors in public and private schools in South Carolina. The goal of SPRI is
to motivate bright, academically talented students to pursue careers in science,
mathematics, or technology. In Summer 2011, 12 students through the GSSM in
Hartsville, SC, worked in the research labs of MUSC faculty as student interns for six
weeks, culminating in the submission of a formal abstract of their work along with a brief
PowerPoint presentation on the last day of their internship. The abstracts are also
published in the GSSM Research Abstract Book and can be submitted to the South
Carolina Junior Academy of Science for competition. Student Interns were also invited
to compete in the MUSC Student Research Day.
Governor’s School Participants and Mentors
Student
Mentor
John C. Elmore, III
Dr. Hai Yao
Clemson-MUSC Bioengineering Program
Kemper Fagan
Dr. John Lemasters
Department of Pharmaceutical Sciences
Chante Glass-Walley
Dr. Gary Aston-Jones
Luke Havens
Dr. Hainan Lang
Department of Pathology & Laboratory Medicine
Li (Angela) Fan
Dr. Sakamuri Reddy
Department of Pediatrics
Maya Mason
Dr. Azizul Haque
Department of Microbiology & Immunology
Barbara (Alison) Moore
Dr. Zhi Zhong
Emily Jean Moore
Dr. Hiroko Hama
Department of Biochemistry & Molecular Biology
Andrew Motts
Dr. Catalin Buhusi
Sahil Patel
Dr. Xuejun Wen
Terral Patel
Dr. Alexander Awgulewitsch
Dept of Medicine, Division of Rheumatology &
Immunology
Erik Schatzer
Dr. Kenneth Chavin
Department of Surgery
Beginning in the Summer of 2010, the College of Graduate Studies started to
coordinate the senior thesis experiences for students attending the Academic Magnet
High School students in Charleston, SC. This was less formal than the GSSM program.
Four students began working on their projects over the months of July and August of
2011.
133
Academic Magnet High School Participants and Mentors
Student
Mentor
Scott Becker
Dr. Mark Kindy
Emma Bradley
Dr. Omar Moussa
Department of Pathology & Laboratory Medicine
Nicholas Hoffman
Dr. Stanley Hoffman
Dept of Medicine, Division of Rheumatology
Joseph Pate
Dr. Jim Norris
Department of Microbiology & Immunology
The program expanded once again in the Summer of 2011, adding students from
Porter Gaud High School to the high school research program. Six students began
working on their projects over the months of July and August 2011.
Porter Gaud Participants and Mentors
Student
Mentor
Apsley Allen
Dr. Samar Hammad
Department of Regenerative Medicine & Cell
Biology
Mallory Banks
Dr. Naren Banik
Department of Neurology
John Everett Craver
Dr. Chris Davies
Department of Biochemistry & Molecular Biology
Riley Daen
Dr. Tamara Nowling
Dept of Medicine, Division of Rheumatology &
Immunology
Frances Grimball
Dr. Yuri Peterson
Allison Pinosky
Dr. Yuri Peterson
134
Christopher Davies, PhD, Program Director
Student’s Name
Matriculation
Date
Mentor
Degree
Sought
*Andrijauskaite, Kristina
Atkison, James
Brice, Sarah
*Broadwater, Margaret
Burns, Tara
Carroll, Brittany
Casu, Fabio
DePalma, Ryan
2009
2011
2010
2005
2007
2010
2008
2011
Daniel Fernandes, PhD
Mirko Hennig, PhD
Ashley Cowart, PhD
John Schwacke, PhD
Chiara Luberto, PhD
Lina Obeid, MD
Mirko Hennig, PhD
Besim Ogretmen, PhD
MS
PhD
MD/PhD
PhD
PhD
PhD
PhD
PhD
Gruber, Jordon
*Hoeferlin, Alexis
Liu, Mengling
Mather, Andrew
Nida, Adrian
Panneer Selvam,
Shanmugam
*Perry, David
Qin, Tingting
Rajagopalan, Vinodh
*Robertson, Rosanna
*Saddoughi, Sahar
Sentelle, David
Snider, Justin
Spainhour, John
*Strickland, Kyle
Thomas, Raquela
2010
2006
2010
2011
2006
2009
Yong-Mei Zhang, PhD
Yusuf Hannun, MD
Leah Siskind, PhD
Jihad Obeid, MD
Besim Ogretmen, PhD
PhD
PhD
PhD
MS
PhD
PhD
2006
2007
2008
2006
2007
2008
2009
2008
2007
2010
Yusuf Hannun, MD
Jim Zheng, PhD
Yusuf Hannun, MD
Christopher Davies, PhD
Besim Ogretmen, PhD
Besim Ogretmen, PhD
Jacek Bielawski, PhD
John Schwacke, PhD
Besim Ogretmen, PhD
MD/PhD
PhD
PhD
PhD
MD/PhD
DMD/PhD
PhD
PhD
MD/PhD
PhD
* degrees awarded this year
Journals
Hu W, Ross J, Geng T, Brice SE, Cowart LA. Differential regulation of dihydroceramide
desaturase by palmitate versus monounsaturated fatty acids: implications for insulin
resistance. Journal of Biological Chemistry 286(19):16596-605, 2011.
feedforward/feedback mechanism in the response to serine availability. Journal of
Biological Chemistry 287(12):9280-9, 2012.
135
Brice SE, Ross JS, Cowart LA. Sphingolipids in obesity, type 2 diabetes, and metabolic
disease. In Sphingolipids in Health and Disease. Erich Gulbins, ed. In press, 2012.
Broadwater MH, Seaborn GT and Schwacke JH. Forensic identification of seal oils
using lipid profiles and statistical models. Journal of Forensic Sciences, in press 2012.
Geng T, Hu W, Snider J, Broadwater MH, Brice SE, Bielawski J, Schwacke J and
Cowart LA. A new diet-induced obesity model reveals dietary fat profile regulates
hepatic ER stress and insulin resistance. In revision, accepted for publication, Diabetes,
2012.
Broadwater MH and Schwacke JH. An integrated framework for the analysis of natural
mixtures of triacylglycerols using RP-HPLC/APCI-MS—preprocessing, statistical
analysis and automated structure determination. Submitted to the Journal of the
American Society for Mass Spectrometry, 2012.
Burns TA, Luberto C. Sphingolipid metabolism and leukemia: a potential for novel
therapeutic approaches. Review. Anticancer Agents Med Chem (9):863-81, 2011.
Rella A, Yang MW, Gruber JD, Montagna MT, Luberto C, Zhang Y-M, Del Poeta M.
Pseudomonas aeruginosa inhibits the growth of Cryptococcus species. Mycopathologia
173:451-461, 2011. (Featured in Global Medical Discovery: Pseudomonas aeruginosa
Inhibits the Growth of Cryptococcus Species, February 20th, 2012).
Mather AR and Siskind LJ. Glycosphingolipids and kidney disease. In Sphingolipids
and Metabolic Disease, L. Ashley Cowart ed, Landes Biosciences. In press. ISBN 9781-4614-0649-5, 2012.
Suriyan Ponnusamy, Shanmugam Panneer Selvam, Shikhar Mehrotra, Toshihiko
Kawamori, Ashley J Snider, Lina M Obeid, Yuan Shao, Roger Sabbadini, Besim
Ogretmen. Communication between host organism and cancer cells is transduced by
systemic Sphingosine kinase/sphingosine-1-phosphate signaling to regulate tumor
metastasis. EMBO Mol Med, in press 2012.
Perry DM, Kitatani K, Roddy P, El-Osta M, Hannun YA. Identification and
characterization of PP2C activation by ceramide. J Lipid Res May 2012 (epub ahead of
print).
Rajagopalan V and Hannun YA. Sphingolipid metabolism and signaling as a target of
cancer therapy. In Cell Death Signaling in Cancer Biology and Treatment, Springer, in
press 2012.
Saddoughi SA, Garrett-Mayer E, Chaudhary U, O'Brien PE, Afrin LB, Day TA, Gillespie
MB, Sharma AK, Wilhoit CS, Bostick R, Senkal CE, Hannun YA, Bielawski J, Simon
GR, Shirai K, Ogretmen B. Results of a phase II trial of gemcitabine plus doxorubicin in
patients with recurrent head and neck cancers: serum C₁₈-ceramide as a novel
136
biomarker for monitoring response. Clin Cancer Res 17(18):6097-105, 2011. Epub 2011
Jul 26.
Senkal CE, Ponnusamy S, Manevich Y, Meyers-Needham M, Saddoughi SA,
Mukhopadyay A, Dent P, Bielawski J, Ogretmen B. Alteration of ceramide synthase
6/C16-ceramide induces activating transcription factor 6-mediated endoplasmic
reticulum (ER) stress and apoptosis via perturbation of cellular Ca2+ and ER/Golgi
membrane network. J Biol Chem 286(49):42446-58, 2011. Epub 2011 Oct 19.
Murshed M, Cevik MO, Ogretmen B. Off-target function of the sonic hedgehog inhibitor
cyclopamine in mediating apoptosis via nitric oxide-dependent neutral
sphingomyelinase 2/ceramide induction. Mol Cancer Ther 11(5):1092-102, 2012. Epub
2012 Mar 27.
Salas A, Ponnusamy S, Senkal CE, Meyers-Needham M, Selvam SP, Saddoughi SA,
Apohan E, Sentelle RD, Smith C, Gault CR, Obeid LM, El-Shewy HM, Oaks J,
Santhanam R, Marcucci G, Baran Y, Mahajan S, Fernandes D, Stuart R, Perrotti D,
Ogretmen B. Sphingosine kinase-1 and sphingosine 1-phosphate receptor 2 mediate
Bcr-Abl1 stability and drug resistance by modulation of protein phosphatase 2A. Blood
117(22):5941-52, 2011. Epub 2011 Apr 28.
Meyers-Needham M, Ponnusamy S, Gencer S, Jiang W, Thomas RJ, Senkal CE and
Ogretmen B. Concerted functions of HDAC1 and microRNA-574-5p repress
alternatively spliced ceramide synthase 1 expression in human cancer cells. EMBO
Molecular Medicine 4(2):78-92, 2011.
Abstracts/Presentations
Kristina Andrijauskaite
April 2012 – Thesis seminar: "Biochemical links between hormonal mediators of
psychological stress and the expression on MUC1 in prostate cancer cells."
Sarah Brice
June 2012 – Society for Heart and Vascular Metabolism Annual Meeting, Oxford, United
Kingdom. Poster presentation: “The role of sphingolipids and (dihydro)ceramide
synthase 5 in diabetic cardiomyopathy.”
March 2012 – Perry V. Halushka MSTP Student Research Day, Medical University of
South Carolina, Charleston, SC. Oral presentation: “The role of sphingolipids and
(dihydro)ceramide synthase 5 in diabetic cardiomyopathy in mice.”
March 2012 – Biochemistry Department Research and Methods Seminar, Medical
University of South Carolina, Charleston, SC. “The role of sphingolipids and
(dihydro)ceramide synthase 5 in diabetic cardiomyopathy.”
137
November 2011 – Southeastern Regional Lipid Conference, Cashiers, NC. Oral
presentation: “A high-myristate diet induces sphingolipid-dependent cardiac
hypertrophy, dysfunction, and autophagy: A requirement for (dihydro)ceramide synthase
5 in sphingolipid-dependent cardiac autophagy.”
Jordon Gruber
November 2011 - ASM Cell-2-Cell Communication Conference, Miami, FL.
“Pseudomonas aeruginosa strains PAO1 and PA14 show unique swarming patterns
and ability to stimulate biofilm growth.”
May 2012 - SC ASM Spring Meeting, Aiken, SC. “Pseudomonas aeruginosa strains
PAO1 and PA14 show unique swarming patterns and ability to stimulate biofilm growth.”
Alexis Hoeferlin
August 2011 – Dissertation seminar: “Regulation of cell death pathways by folate
metabolism.”
Andrew Mather
January 2012 - Department of Medicine Student Research Day, Charleston, SC. Poster
presentation: "Accumulation of glucosylceramide and lactosylceramide in lupus
nephritis:
biomarker
or
mediator
of
disease?"
November 2011 - Southeastern Regional Lipid Conference, Cashiers, NC. Oral
presentation: "Accumulation of glucosylceramide and lactosylceramide in lupus
nephritis: biomarker or mediator of disease?"
David Perry
May 2012 – Dissertation seminar: "Activation of protein phosphatase 2C ceramide and
essential role of acid sphingomyelinase in IL-6 synthesis."
Rosanna Robertson
November 2011 – dissertation seminar: "Developing new drug targets in Neisseria
gonorrhoeae: functional and structural studies of AmiC, an N-acetylmuramyl-L-alanine
amidase required for bacterial cell separation."
Sahar Saddoughi
March 2012 – dissertation seminar: "FTY720 Mimics Ceramide to Target I2PP2A/SET
Oncoprotein for PP2A Activation Leading to Lung Tumor Suppression"
David Sentelle
March 2011 - International Charleston Ceramide Conference Villars Switzerland, oral
presentation: “Ceramide's role in lethal mitophagy of head and neck cancer.”
March 2012 - MUSC Scholars Day, Charleston SC, poster presentation: “Ceramide
mediates LC3B dependent mitophagy and tumor suppression.”
138
June 2012 – dissertation seminar: "Ceramide Mediates LC3B Dependent Mitophagy
and Tumor Suppression."
April 2011 American Association of Cancer Research - 102nd Annual Meeting, Orlando
FL poster presentation: “Ceramide suffocates cancer cells to death: Regulation of
mitophagy by ceramide signaling.”
Kyle Strickland
November 2011 – dissertation seminar: "The cytosolic and mitochondrial pathways of
10-formyltetrahydrofolate metabolism."
Raquela Thomas
2011 Hollings Cancer Center Annual Research Retreat and 2012 Hollings Cancer
Center Lipid Signaling in Cancer Program Retreat. Poster presentations: “Regulation of
human dihydroceramide synthase 1 (dhCerS1/LASS1) gene in head and neck
squamous cell carcinoma.”
Kristina Andrijauskaite
First place poster presentation, MUSC Student Research Day 2011. “Effects of cortisol
and norepinephrine on the expression of the tumor antigen MUC1 in DU-145 prostate
cancer cells.”
Sarah Brice
NIH Predoctoral Individual Fellowship, Ruth L. Kirschstein Award, National Institute of
Diabetes and Digestive and Kidney Diseases (activated September 2011).
Jordon Gruber
Honorable mention oral presentation, MUSC Student Research Day 2011, “Bioactive
sphingolipids regulate cardiac hypertrophy and autophagy in lipid overload: A role for
myristate and its derivatives.”
Travel award to American Society for Microbiology Cell to Cell Communication
Conference in Miami, FL, November 2011.
Second place graduate student poster presentation: “Co-strain biofilm and their
influence on group behaviors and total virulence.” South Carolina ASM, May 2012.
Predoctoral grant from the Cystic Fibrosis Foundation. “The influence of
dihydroxyquinoline (DHQ) on quorum-sensing and virulence factor production in
Pseudomonas aeruginosa.” December 2011.
Andrew Mather
Second place poster presentation, MUSC Student Research Day 2011: “Accumulation
of glucosylceramide and lactosylceramide in lupus nephritis: biomarker or mediator of
disease?”
139
Shanmugam Panneer Selvam
First prize oral presentation, 2011 Edith Peng Award for Research Excellence, Annual
Hollings Cancer Center Symposium: “Regulation of telomerase by sphingosine kinase-2
/ sphingosine-1-phosphate signaling in lung cancer.”
David Sentelle
Travel award, 6th International Charleston Ceramide Conference, Villars Switzerland,
March 2011.
First place poster presentation: “Ceramide mediates LC3B dependent mitophagy and
tumor suppression.” MUSC Scholars Day, Charleston SC, March 2012
F30 NRSA Individual Fellowship, National Institute of Dental and Craniofacial Research,
2011-2012.
Goals for 2012-2013
Amidst a period of change within the Department of Biochemistry & Molecular Biology,
our graduate program is being reviewed and revised with the overarching goal of
attracting the brightest students to the department and furnishing them with requisite
skills and knowledge in a challenging and stimulating environment, in readiness for
outstanding careers in science. At present, existing courses are being updated and new
ones are also being developed. New courses include one themed on RNA biology,
another that will teach advanced topics in Biochemistry and a new Spring Selective on
diabetes. Journal clubs and seminar programs are also being overhauled. Overall, the
realignment of courses will reflect the evolving composition of the Department and
further changes can be anticipated upon appointment of a new Chair. In tandem, we
plan to monitor the progress of students more closely to ensure that the mentor and
department continue to provide the optimal environment for training, including
opportunities for development that will increase their competiveness in an increasingly
tough scientific environment.
140
Richard Swaja, PhD (Director)
Martine LaBerge, PhD (Chair – Clemson Bioengineering Department)
Student’s Name
Angela Alexander
Vincent Beachley
Sarah Cisewski
Wenjun He
Eleni Katsanevakis
Jonathan Kuo
Xiaowei Li
Xiaoyan Liu
Rebekkah Merrell
Emily Ongstad
Erin Pardue
Suzanne Parks
Changcheng Shi
Yu Tan
Van Tran
Michael Vaughn
Benjamin Whatley
Gregory Wright
Yongren Wu
Matriculation Date
2008
2006
2010
2007
2007
2006
2006
2006
2010
2007
2006
2009
2008
2011
2008
2009
2007
2009
2008
Mentor
Dr. Ning Zhang
Dr. Xuejun Wen
Dr. Hai Yao
Dr. HaiYao
Dr. Ning Zhang
Dr. Hai Yao
Dr. Xuejun Wen
Dr. Xuejun Wen
Dr. Qian Kang
Dr. Rob Gourdie
Dr. Scott Argraves
Dr. Rick Visconti
Dr. Hai Yao
Dr. Xuejun Wen
Dr. Xuejun Wen
Dr. Xuejun Wen
Dr. Xuejun Wen
Dr. Hai Yao
Dr. Hai Yao
Degree Sought
PhD
PhD/Graduated 2012
PhD
PhD
PhD
PhD
PhD
PhD
MS
PhD
PhD
PhD
PhD
PhD
PhD
PhD
PhD
PhD
PhD
Journals
1. Jonathan Kuo, Changcheng Shi, Sarah Cisewski, Li Zhang, Michael Kern,
and Hai Yao, “Regional Cell Density Distribution and Oxygen Consumption
Rates in Porcine TMJ Discs: An Explant Study”, Osteoarthritis and Cartilage, 19,
No. 7, 911-918 (July 2011)
2. Jonathan Kuo, Gregory Wright, David Bach, Elizabeth Slate, and Hai Yao,
“Effect of Mechanical loading on Electrical Conductivity in Porcine TMJ Discs”,
Journal of Dental Research,90, No. 10, 1216-1220 (October 2011)
3. Emily Ongstad, Michael Yost, Richard Goodwin, Harold Friedman, Su Fann,
Ghatam Ghatnekar, and Rob Gourdie, “Regenerative Pharmacology of
Implanted Materials and Tissue Engineered Constructs”, Regenerative
Pharmacology, Cambridge University Press (October 2011)
141
4. Emily Ongstad, Michael O’Quinn, Ghatam Ghatnekar, Michael Yost, and Rob
Gourdie, “A Connexin-43 Mimetic Peptide Promotes Regenerative Healing and
Improves Mechanical Properties in Skin and Heart”, Wound Healing Society
Yearbook,3 (November 2011)
5. Kelvin Brockbank, Edward Rahn, Gregory Wright, Zhu Chen, and Hai Yao,
“Impact of Hypothermia on Chondrocyte Viability and Cartilage Matrix
Permeability After One Month of Refrigerated Storage”, Transfusion Medicine
and Hemotherapy, 38, No. 6, 387-392 (December 2011)
6. Rob Gourdie, James Rhett, Emily Ongstad, Joseph Palatinus, and Michael
O’Quinn, “Translating Basic Research on CX-43 Gap Junctions into Therapies
for Reducing Scarring and Cardiac Arrhythmia”, Connexin Cell Communication
Channels: Roles in the Immune System and Immunopathjology, CRC Press
(December 2011)
7. Ule Mendes, Eric Brown, Emily Ongstad, James Slis, and Joseph Goldman,
“Functional Recovery of Fluid Drainage Precedes Lymphangiogenesis in Acute
Murine Foreleg Lymphedema”, American Journal of Heart Circulation
Physiology, 32, No. 16, 112-116 (March 2012)
8. Emily Ongstad and Rob Gourdie, “Myocyte-Fibroblast Electrical Coupling: The
Basis of a Stable Relationship?”, Cardiovascular Research, 93, 215-217 ((March
2012)
9. Gregory Wright, Jonathan Kuo, Thierry Bacro, Elizabeth Slate, and Hai Yao,
“Effect of Mechanical Loading on Electrical Conductivity in Human TMJ Discs is
Sex Dependent”, Journal of Dental Research, 90, No. 12, 946-950 (June 2012)
10. James Rhett, Emily Ongstad, Joseph Jourdan, and Rob Gourdie,
“Characterization of the CX-43 Gap Junction Perinexus by High-Sensitivity
Labeling”, Journal of Membrane Biology, 25, No. 2, 433-438 (June 2012)
Abstracts
1. Emily Ongstad, Micahel O’Quinn, James Rhett, Steven Bowers, Thomas
Baudino, Thomas Borg, and Rob Gourdie, “Effects of the Connexin-43 CT on
Myocyte-Fibroblast Adhesion Following Cardiac Injury”, Proceedings of
International Gap Junction Conference, Ghent, Belgium (August 2011)
2. Emily Ongstad, Michael O’Quinn, James Rhett, and Rob Gourdie, “Effects of
Connexin-43 CT Mimetic Peptide on Cell Interactions in a Novel In-Vitro 3D
Model of the Infarct Border Zone”, Proceedings of the North Carolina Tissue
Engineering and Regenerative Medicine Conference, Winston-Salem, North
Carolina (November 2011)
142
3. Gregory Wright, Jonathan Kuo, Thierry Bacro, and Hai Yao, “Mechanical
Strain Affects Conductivity in Human TMJ Discs”, Proceedings Second Annual
Scholar’s Day, MUSC Department of Dental Medicine, Charleston, South
Carolina (February 2012)
4. Ule Mendez, Eric Brown, Emily Ongstad, James Slis, and Joseph Goldman,
Murine Foreleg Lymphedema”, Proceedings of Gordon Research Conference,
Ventura, California (February 2012)
5. Jonathan Kuo, Gregory Wright, Michael Kern, and Hai Yao, “Glucose and
Lactate Diffusion in Porcine TMJ Disc”, Proceedings of 41st Annual Meeting of
the American Association for Dental Research, Tampa, Florida (March 2012)
6. Sarah Cisewski, Yongren Wu, and Hai Yao, “Nutrition Metabolic Rates of
Normal Human Intervertebral Disc Cells”, Proceedings of 58th Annual
Orthopaedic Research Society Meeting, San Francisco, California (April 2012)
7. Yongren Wu, Sarah Cisewski, and Hai Yao, “Effect of Cartilage Endplates on
Nutrition Distribution Inside Human Intervertebral Discs: A Finite Element
Analysis”, Proceedings of the 58th Annual Orthopaedic Research Society
Meeting, San Francisco, California (April 2012)
8. Sarah Cisewski, “Intervertebral Disc Regeneration”, Proceedings of the
International Spine Care Conference, Kiawah Island, South Carolina (May 2012)
Presentations
1. Emily Ongstad, Michael O’Quinn, James Rhett, Steven Bowers, Thomas
Baudino, Thomas Borg, and Rob Gourdie, “Effects of the Connexin-43 CT on
Myocyte-Fibroblast Adhesion Following Cardiac Injury”, International Gap
Junction Conference, Ghent, Belgium (August 2011)
2. Sarah Cisewski, “Intervertebral Disc Form and Function”, MUSC Lecture to
Orthopaedic Residents (October 2011)
3. Emily Ongstad, Michael O’Quinn, James Rhett, and Rob Gourdie, “Effects of
Connexin-43 CT Mimetic Peptide on Cell Interactions in a Novel In-Vitro 3D
Model of the Infarct Border Zone”, North Carolina Tissue Engineering and
Regenerative Medicine Conference, Winston-Salem, North Carolina (November
2011)
4. Gregory Wright, Jonathan Kuo, Thierry Bacro, and Hai Yao, “Mechanical
Strain Affects Conductivity in Human TMJ Discs”, Second Annual Scholar’s Day,
MUSC Department of Dental Medicine, Charleston, South Carolina (February
2012)
143
5. Ule Mendez, Eric Brown, Emily Ongstad, James Slis, and Joseph Goldman,
Murine Foreleg Lymphedema”, Gordon Research Conference, Ventura,
California (February 2012)
6. Emily Ongstad and Rob Gourdie, “Role of the Connexin-43 CT on MyocyteFibroblast Interactions in a 3D Model of the Infarct Border Zone”, Cardiovascular
Developmental Biology Symposium, Charleston, South Carolina (March 2012)
7. Gregory Wright, Alaa Ahmad, Richard Gross, and Hai Yao, “Management of
Kyphotic Deformity Associated with Early Onset Scoliosis: A Biomechanical
Comparison of Different Methods”, Siegling Society Research Day, Charleston,
South Carolina (April 2012)
8. Jonathan Kuo, Gregory Wright, Michael Kern, and Hai Yao, “Glucose and
Lactate Diffusion in Porcine TMJ Disc”, 41st Annual Meeting of the American
Association for Dental Research, Tampa, Florida (March 2012)
9. Sarah Cisewski, Yongren Wu, and Hai Yao, “Nutrition Metabolic Rates of
Normal Human Intervertebral Disc Cells”, 58th Annual Orthopaedic Research
Society Meeting, San Francisco, California (April 2012)
10. Yongren Wu, Sarah Cisewski, and Hai Yao, “Effect of Cartilage Endplates on
Nutrition Distribution Inside Human Intervertebral Discs: A Finite Element
Analysis”, 58th Annual Orthopaedic Research Society Meeting, San Francisco,
California (April 2012)
11. Sarah Cisewski, “Intervertebral Disc Regeneration”, International Spine Care
Conference, Kiawah Island, South Carolina (May 2012)
Vincent Beachley received the PhD Degree in Bioengineering in May 2011 and
accepted a post doctoral position at Johns Hopkins University.
Rebekkah Merrell received the MS Degree in December 2011 and accepted a position
in industry.
Sarah Cisewski received the 2012 Austin T. Moore Leadership Award at Clemson
University.
Jonathan Kuo received the 2012 Clemson University Outstanding Graduate Student
Research Award.
144
Angela Alexander was selected to attend a Future Faculty Leadership Workshop at MIT
in July 2011.
Sarah Cisewski received a National Science Foundation Graduate Career Research
Award.
Emily Ongstad received a NIH Ruth Kirschstein National Research Service Award F31
Pre-Doctoral Fellowship.
Sarah Cisewski and Suzanne Parks mentored high school and junior high school
students as part of the STEM (Science, Technology, Engineering and Mathematics)
Program in Charleston.
Angela Alexander was elected President of the MUSC Multicultural Graduate Student
Association (MGSA)..
Angela Alexander served as Community Service Chair of the MUSC Multicultural
Graduate Student Association.
Jonathan Kuo was selected to chair the opening session of the 2012 Annual Society for
Dental Research Conference in Tampa, Florida.
Angela Alexander served as MGSA Representative to MUSC Minority Student Advisory
Board.
Gregory Wright mentored students and delivered lectures related to biomechanics and
bioengineering research for the 2011 state-wide LEGO Science Competition.
Suzanne Parks and Wenjun He served as MUSC Presidential Scholars for the 2011-12
academic year.
Suzanne Parks, Sarah Cisewski, and Gregory Wright coordinated a “Bioengineering
Day” at MUSC for students from Fort Dorchester High School as part of the STEM
Program.
Glenn Hepfer mentored a Charleston Academic Magnet high school student for his
senior thesis in regenerative medicine.
The joint Clemson-MUSC Bioengineering Program completed its eighth year in May
2012. During the 2011-2012 year, the highlight was moving to the Bioengineering
Building on the NIH campus which was dedicated in October 2011. This marked a
milestone for the program in that it provides dedicated space for the Clemson-MUSC
faculty and students and proximity to scientific and administrative collaborators.
Enrollment continued strong with a total of 25 graduate students and post-docs, and
145
graduate students continued to enjoy a high degree of success obtaining research and
education support grants from NSF, NIH, and foundations. Students also maintained a
high level of scientific productivity with regard to journal publications, presentations, and
abstract submittals. Clemson Bioengineering students continued to integrate into
MUSC activities and programs through leadership in student government and social
organizations, participation in university outreach and student research opportunities,
mentoring high school and junior high school teachers and students in local and statewide science education programs, and mentoring high school and undergraduate
students during summer research experiences. Clemson Bioengineering student
accomplishments and contributions to MUSC activities were recognized by several
awards throughout the year. Two special awards included the Clemson University
Graduate Student Leadership and Outstanding Research Awards which both went to
Clemson-MUSC graduate students (Jonathan Kuo and Sarah Cisewski). Six graduate
students also participated as coordinators and program facilitators for a major national
conference conducted in December in Charleston - the SmartState “Conference on
Realizing a Knowledge-Based Economy: Bridging Academia, Government, and
Industry”. One student (Vincent Beachley) received his PhD degree and one student
(Rebekkah Merrell) received her MS degree during the year, and both received
excellent positions after graduation - testimonials to the quality education and high
regard of the program. The joint Clemson-MUSC Bioengineering Program continued to
develop and meet its primary mandate of bridging the life and physical sciences to
enable collaborations among faculty and students at the participating universities.
The 2012-2013 term is the continuation of a transition period for the Clemson-MUSC
Bioengineering Program – one that reflects maturation and true integration of the
program between the universities. The beginning of the next phase was marked by the
dedication and occupancy of the new Bioengineering Building at MUSC. Activities are
currently focused on developing a new inter-university agreement to formally define the
program and dealing with losses of faculty by the end of the summer of 2012. Major
goals during the 2012-2013 year include (l) preparation and approval of the ClemsonMUSC agreement for the next five years of the program, and (2) hiring new faculty to
replace three who recently left Clemson and additional staff to augment current
scientific expertise. Other goals are to increase support of student research and
education through agency and foundation grants, to expand collaborations among the
colleges and departments at MUSC, to maintain a high level of participation in university
activities and outreach efforts, and to increase the number of Clemson graduate
students mentored by MUSC faculty. The program continues to be a credit to both
universities and is a model for collaborative efforts aimed at bridging disciplines and
organizations.
146
Division of Biostatistics & Epidemiology
Viswanathan Ramakrishnan, PhD, Director
Student’s Name
Boan, Andrea
Cassarly, Christy
Chiuzan, Codruta
Cornelius, Monica
Dasgupta, Purbasha
Davis, Melanie
Ellerbe, Caitlyn
Fan, Liqiong
Logan, Sarah
Rachel Moss
Nicholas, Katherine
Onicescu, Georgiana
Parker, Anthony
Payne, Elizabeth
Matriculation
Date
2005
2011
2009
2007
2010
2011
2009
2011
2006
2011
2010
2010
2007
2011
Mentor
Daniel Lackland
(Renee’ Martin)*
Elizabeth Garrett-Mayer
Elizabeth Pickelsimer
Andrew Lawson
(Renee’ Martin)*
Valerie Durkalski
(Renee’ Martin)*
Joyce Nicholas
(Elizabeth Garrett-Mayer)*
(Valerie Durkalski)*
Andrew Lawson
Elizabeth Slate
(Viswanathan
Ramakrishnan)*
Prince Nelson, Sybil
2010
(Bethany Wolf)*
Robinson, Kyra
2010
Valerie Durkalski
Rotejanapresert, Chawarat 2011
(Andrew Lawson)*
Santos, Claritza
2009
(Kelly Hunt)*
Small, James
2011
(Anbesaw Selassie)*
Teklehaimanot, Abeba
2011
(Jordan Elm)*
Voronca, Delia
2011
(Mulugeta Gebregziabher)*
Weng, Yanqiu
2008
Yuko Palesch
Wheless, Lee
2005
Anthony Alberg
*Names in parentheses are Program of Study Advisors
Degree
Sought
PhD
PhD
PhD
PhD
MS
PhD
PhD
PhD
PhD
PhD
PhD
PhD
PhD
PhD
PhD
PhD
PhD
MS
PhD
MS
PhD
PhD
PhD
Journals
Hudspeth M.P., Heath T. S., Chiuzan C., Garrett-Mayer E., Folinic Acid Administration
after Methotrexate Graft-Versus-Host Disease Prophylaxis in Pediatric Allogeneic Stem
Cell Transplantation, Bone Marrow Transplantation, May 2012, 1-4
Prisciandaro J., DeSantis S., Chiuzan C., Brown D., Brady K.T., Tolliver B., Impact of
Depressive Symptoms on Future Alcohol Use in Patients with Co-occurring Bipolar
Disorder and Alcohol Dependence: A Prospective Analysis in an 8-Week Randomized
147
Controlled Trial of Acamprosate, Alcoholism: Clinical and Experimental Research,
March 2012, Vol. 36, No. 3, 490-496
Korte J.E., Magruder K.M., Chiuzan C., Logan S., Killeen T., Bandyopadhyay D., Brady
K.T., Assessing drug use during follow-up: direct comparison of candidate outcome
definitions in pooled analyses of addiction treatment studies, Am J Drug Alcohol Abuse,
Sep 2011, 37(5):358-66
Ellerbe CN, Gebregziabher M, Korte JE, Mauldin J, Hunt, KJ. Quantifying the impact of
GDM, maternal weight and race on birthweight via quantile regression. (submitted:AJE)
Wilson DK, Lawson AB, Ellerbe C, Kugler KA, Meyers DC, Coulon SM, Lawman HG.
Spatial Context and Social Environmental Predictors of Walking in an Underserved
Community: The PATH Trial. (submitted: SSTE)
Fowler EB, Woolworth JA, Quigley DI, Ellerbe C, Wolff DJ. Validation and Clinical Utility
Assessment of an Automated Capture/Analysis System for FISH to Detech Urothelial
Carcinoma. (submitted)
Fowler EB, Woolworth JA, Ellerbe C, Sobolesky PM, Shao Y, Keane T, Watson DK,
Wolff D, Moussa O. Analysis of Apoptosis Regulators, Inhibitors of Apoptosis genes,
BBFAR, and Stannin as Diagnostic Markers for Bladder Cancer (submitted)
Hunt KJ, Marlow NM, Gebregziabher M, Ellerbe CN, Mauldin J, Mayorga ME, Korte JE
(2012) Impact of maternal diabetes on birthweight is greater in non-Hispanic blacks than
in non-Hispanic whites. Diabetologia 55(4): 971-980.
Lawson AB, Onicescu G, Ellerbe C. (2011) Foot and mouth disease revisited: Reanalysis using Bayesian spatial susceptible-infectious-removed models. Spatial and
Spatio-temporal Epidemiology 2(3): 185-194.
Korte J, Magruder K, Chiuzan C, Logan S, Killeen T, Bandyopadhyay D, Brady K.
Assessing drug use during follow-up: direct comparison of candidate outcome
definitions in pooled analyses of addiction treatment studies. Am J Drug Alcohol Abuse,
2011; 37(5): 358-366
Ricci R, Salatino A, Logan S, Funk, AP. et al. Imaging the Neural Mechanisms of VisioSpatial Perception with Interleaved TMS/fMRI Technique: Preliminary Evidence.
Experimental Brain Research (Submitted).
Logan S, Nicholas J, Carpenter L, King L, Garret-Mayer E, Charles J. High Prescription
Drug Utilization and Associated Costs Among Medicaid-Eligible Children with Autism
Spectrum Disorders Identified by a Population-based Surveillance Network. Annals of
Epidemiology, 2012. 22; 1:1-8.
148
Nicholas J, Carpenter L, King L, Jenner W, Wahlquist A, Logan S, Charles J.
Completeness of case ascertainment for surveillance of autism spectrum disorders
using the autism developmental disabilities monitoring network methodology. Disability
and Health Journal. 2012. In Press.
Andrew B. Lawson, Georgiana Onicescu, Caitlyn Ellerbe (2012). Foot and mouth
disease revisited: re-analysis using Bayesian spatial Susceptible-Infective-Removed
models. Spat Spattemporal Epidemiol.,Sep 2011;2(3) 185-194.
Carter CL, Onicescu G, Cartmell KB, Sterba KR, Tomsic J, Alberg AJ. The comparative
effectiveness of a team-based versus group-based physical activity intervention for
cancer survivors. Support Care Cancer.Sep.2011:137163
Kasman L, Onicescu G., Voelkel-Johnson C (2012). Histone deacetylase inhibitors
restore cell surface expression of the coxsackie adenovirus receptor and enhance CMV
promoter activity in castration-resistant prostate cancer cells. Prostate Cancer, Jan
2012, 137163.
Kathleen B. Cartmell, Matthew J. Carpenter, Sharon R. Biggers, Georgiana Onicescu,
Elizabeth G. Hill, Secondhand smoke exposure in youths in relation to the strength and
adherence of parental rules against smoking at home and in the car, Public Health
Reports,2011 Jul-Aug;126(4):575-82.
Samantha Solito, Erika Falisi, Claudia Marcela Diaz-Montero, Andrea Doni, Laura
Pinton, Antonio Rosato, Samuela Francescato, Giuseppe Basso, Paola Zanovello,
Georgiana Onicescu, Elizabeth Garrett-Mayer, Alberto J. Montero, Vincenzo Bronte,
Susanna Mandruzzato. A human promyelocytic-like population is responsible for the
immune suppression mediated by myeloid-derived supressor cells. Blood. Aug
2011;118(8):2254-65.
Parker A, Yuen H; Slate E. Dental Care Utilization Among Dentate Adults with Asthma:
Findings from the 2008 Behavioral Risk Factor Surveillance System. Journal of Public
Health Dentistry.
Zhao W, Weng Y. Block urn design - a new randomization algorithm for sequential trials
with two or more treatments and balanced or unbalanced allocation. Contemporary
Clinical Trials. 2011, 32(6): 953-961.
Weng Y, Korte JE. Racial disparities in being recommended to surgery for oral and
oropharyngeal cancer in the United States. Community Dentistry and Oral
Epidemiology. 2012, 40(1): 80-88.
Weng Y, Zhao W, Palesch YY. Impact of safety monitoring on error probabilities of
binary efficacy outcome analyses in large Phase III group sequential trials.
Pharmaceutical Statistics. 2012, DOI: 10.1002/pst.1520.
149
Barnado A, Wheless L, Meyer AK, Gilkeson GS, Kamen DL. “Quality of Life in Patients
with Systemic Lupus Erythematosus (SLE) Compared to Related Controls within a
Unique African American Cohort.” Lupus 2012; 21:563-9.
MW, Alberg AJ.
“A community-based study of nucleotide excision repair
polymorphisms in relation to risk of non-melanoma skin cancer.” J Invest Dermatol
2012; 132:1354-62.
Ruczinski I*, Jorgensen TJ* (co-first authors), Shugart YY, Berthier-Schaad Y, Kessing
B, Hoffman-Bolton J, Helzlsouer KJ, Kao WHL, Wheless L, Francis L, Alani RM,
Strickland PT, Smith MW, Alberg AJ. “Nonmelanoma skin cancer as a marker of a
cancer-prone phenotype: Potential role of DNA repair gene variants.” (in press,
Carcinogenesis)
MW, Alberg AJ. “Variants in Hedgehog genes and the risk of cancer.” (in press,
Cancer Epidemiol)
Alberg AJ, Jorgensen TJ, Ruczinski I, Wheless L, Shugart YY, Berthier-Schaud Y,
Kessing B, Hoffman-Bolton J, Helzlsouer KJ, Kao WHL, Francis L, Alani R, Smith MW,
Strickland PT. “DNA repair gene variants in relation to overall cancer risk: A populationbased study.” (submitted, Cancer Epidemiol Biomarkers Prev)
“The effect of calpain inhibition on visual pathway function during the course of chronicprogressive optic neuritis.” (submitted, J Neurosci)
MW, Alberg AJ. “Fibroblast growth factor 2 receptor polymorphisms associated with
increased risk of basal cell carcinoma.” (submitted, J Invest Dermatol)
Kessing B, Hoffman-Bolton J, Ellerbe C, Francis L, Strickland PT, Alani RM, Smith MW,
Alberg AJ, Ruczinski I. “Practical consideration in exploring gene-gene interactions: An
example using nucleotide excision repair pathway genes in relation to nonmelanoma
skin cancer.” (in preparation)
Wheless L*, Lam TK* (co-first authors), Jorgensen TJ, Ruczinski I, Berthier-Schaad Y,
Kessing B, Hoffman-Bolton J, Woodward L, Yao Y, Strickland PT, Smith MW, Alberg
AJ. “XPD variant Lys751Gln is associated with increased risk of lung cancer
independent of smoking” (in preparation)
150
Barnado A, Wheless L, Meyer AK, Gilkeson GS, Kamen DL. “Pregnancy Outcomes
among African American Patients with Systemic Lupus Erythematosus (SLE) Compared
to Controls.” (in preparation)
Abstracts
Boan, Andrea D., Bachman, David L., Adams, Robert J., Feng, Wuwei, Egan, Brent M.,
Nicholas, Joyce S., et al; Racial disparities in repeat admissions for ischemic stroke
patients <65years of age [abstract]. Journal of Clinical Hypertension 2012;14 Suppl 1: 2.
Malek, Angela M., Adams, Robert, Boan, Andrea D., Feng, Wayne, Lackland, Daniel;
Blood pressure and acute ischemic stroke [abstract]. Journal of Clinical Hypertension
2012;14 Suppl 1: 80.
Hudspeth M.P., Heath T. S., Chiuzan C., Garett-Mayer E., Nista E., Clonal Evolution Is
a Stronger Predictor Than Disease Status of Disease-Free Survival After Pediatric
Hematopoietic Stem Cell Transplantation, Biology of Blood and Marrow Transplantation
Vol. 17, 2011, Issue 2, Supplement, pages S266-S267
Logan S, Nicholas J, King L, Charles J, Jenner W, Carpenter L. Assessing Medication
Adherence in Autism Spectrum Disorders. International Meeting for Autism Research,
Toronto, ON, May 2012.
Carpenter L, Logan S, King L, Charles J, Devane L, Singh I, Jenner W, Cheely C,
Nicholas J. Omega-3 Fatty Acid Supplementation in Children with Autism. International
Meeting for Autism Research, Toronto, ON, May 2012.
Georgiana Onicescu, Andrew B. Lawson, Suzanne McDermott, C. Marjorie Aelion, Bo
Cai. Cumulative spatial and temporal exposure modeling of soil metals and
developmental disabilities in children. GEOMED Oct 2011, Victoria, BC, Canada
Georgiana Onicescu, Andrew B. Lawson, Suzanne McDermott, C. Marjorie Aelion, Bo
Cai. Cumulative spatial and temporal exposure modeling of soil metals and
developmental disabilities in children. Student research day, Nov 2011, Charleston, SC
MW, Alberg AJ.
“A community-based study of nucleotide excision repair
polymorphisms in relation to risk of non-melanoma skin cancer.” Abstract for poster
presentation, AACR annual meeting, Chicago, IL, 3/31-4-3/12
Kessing B, Hoffman-Bolton J, Francis L, Strickland PT, Alani RM, Smith MW, Alberg AJ,
Ruczinski I. “Practical consideration in exploring gene-gene interactions: An example
using nucleotide excision repair pathway genes in relation to nonmelanoma skin
151
cancer.” Abstract for poster presentation, Society for Investigative Dermatology annual
meeting, Raleigh, NC, 5/8-5/12/12
Presentations
Boan, Andrea D., Bachman, David L., Adams, Robert J., Feng, Wuwei, Egan, Brent M.,
Nicholas, Joyce S., et al; Racial disparities in repeat admissions for ischemic stroke
patients <65years of age. American Society of Hypertension 2012 Annual Scientific
Meeting & Exposition, New York, NY, May 19, 2012.
Boan AD, Bachman DL, Adams RJ, Feng W, Egan BM, Nicholas JS, Lawson AB,
Lackland DT. Racial Disparities in Repeat Admissions for Ischemic Stroke Patients Less
than 65 years of Age. Posted presented November 4, 2011 at The Perry V. Halushka
Medical University of South Carolina Student Research Day, Charleston, SC.
Boan AD, Bachman DL, Adams RJ, Lackland DT. Associated Risk Factors and
Outcomes Among Stroke Patients. Poster presented September 15, 2011 at the 17th
Annual Diabetes Fall Symposium for Primary Health Care Professionals, N. Charleston,
SC.
Chiuzan C, Southern Regional Council on Statistics (SRCOS) - Poster Presentation,
Dose Finding Design for Modeling Immunotherapy Outcomes: A Practical Approach in a
Metastatic Melanoma Phase I Trial, June 2012
Chiuzan C, Eastern North American Region (ENAR) - Poster Presentation, Dose
Finding Design for Modeling Immunotherapy Outcomes: A Practical Approach in a
Metastatic Melanoma Phase I Trial, April 2012
Chiuzan C, Hollings Cancer Center Retreat, MUSC - Poster Presentation, Dose Finding
Design for Modeling Immunotherapy Outcomes: A Practical Approach in a Metastatic
Melanoma Phase I Trial, November 2011
Cornelius M, Division of Biostatistics and Epidemiology, Medical University of South
Carolina. Tea Time for Science.October 10, 2011. “Assessing Prevalence of Traumatic
Brain Injury in South Carolina Prisons”.
Ellerbe C, Lawson AB, Wilson DK, Kugler K, Coulon S, St. George S, Van Horm ML.
“Bayesian hierarchical modeling approach for understanding factors related to walking
(The PATH Trial).” (2012) Active Living Research Conference. San Diego, CA. (poster
presentation)
Ellerbe CN, Elm J, Ramakrishnan V, Durkalski V. "Seamless Phase II/III Adaptive Dose
Finding Design for Longitudinal Data in Safety/Efficacy Clinical Trials." (2012) MUSC
Department of Medicine Research Day. Medical University of South Carolina,
Charleston, SC. (poster presentation)
152
Ellerbe CN, Elm J, Ramakrishnan V, Durkalski V. "Seamless Phase II/III Adaptive Dose
Finding Design for Longitudinal Data in Safety/Efficacy Clinical Trials." (2011) MUSC
Department Perry Halushka Student Research Day. Medical University of South
Carolina, Charleston, SC. (poster presentation)
Logan S. Introduction to Skull Anatomy. Invited lecture at MUSC, June 2011.
Logan S. Introduction to the Oral Cavity Anatomy. Invited lecture at MUSC, July 2011.
Logan S. The History of Epidemiology. Invited lecture at MUSC, September 2011.
Logan S. Methods of data summarization & presentation. Invited lecture, MUSC,
October 2011.
King L, Logan S. ASD in SC- Unique Data Linkages and What They Tell Us. Presented
at the Autism Spectrum Disorders Scientific Meeting. Charleston, SC. November 2011.
Carpenter L, Logan S, King L, Charles J, Devane L, Singh I, Jenner W, Cheely C,
Nicholas J. Omega-3 Fatty Acid Supplementation in Children with Autism. Presented at
the International Meeting for Autism Research, Toronto, ON, May 2012.
Logan S. An update on the Community Advisory Committee. Presented at the
International Society for Autism Research Annual Business Meeting, for the
International Meeting for Autism Research, Toronto, Ontario. May 2012.
Logan S, Charles, J. About Autism Awareness, Invited guest speaker on the 105.5 The
Bridge with Mike Allen radio show. April 2012.
Logan S, De LaRosa, A. Invited speaker at Mason Preparatory School for Autism
Awareness Month, April 2012.
Logan S, Carpenter L. Invited speaker at Mason Preparatory School for Autism
Awareness, May 2012.
Nicholas, K., Zhao, W., and Durkalski, V.; “The impact of covariate adjustment at
randomization and analysis: Understanding differences in superiority and non-inferiority
designs”; Southern Regional Council on Statistics Summer Research Conference,
Jekyll Island, GA. (June 2012).
Anthony Parker, Slate E.H., Bandyopadhyay D. “New Statistical Methods for the
Analysis of Periodontal Data”. Norfolk State University. April 2012.
Anthony Parker, Bandyopadhyay D., Slate E.H. “A Spatial Beta Regression Model for
informatively-present Periodontal Data”. Southern Regional Council on Statistics. June
2011.
153
Robinson K, Invited Junior Speaker to SC Chapter of the American Statistical
Association’s Palmetto Symposium, April 2012 (Not formally published, though):
Robinson K. The Analysis of Acute Stroke Clinical Trials with Responder Analysis
Outcomes. Oral presentation given at the SC Chapter of the American Statistical
Association’s Palmetto Symposium. April 2012, Columbia, SC.
Weng Y, Quantification of Impact of Safety Monitoring on Type I Error and Power of
Efficacy Analysis in Phase III Group Sequential Clinical Trial. Joint Statistical Meetings
(JSM), Miami Beach, FL, 2011.
Weng Y, A General Approach for Power Estimation in Large Group Sequential Trials
with Binary Efficacy and Safety Endpoints. ENAR 2012, Washington, DC, 2012.
Andrea Boan
American Society of Hypertension 2012 Annual Scientific Meeting & Exposition Young
Investigator-In-Training Abstract Competition – Third place recipient.
Consortium for Southeastern Hypertension Control Post-doctoral Fellowship Award
Cody Chiuzan
Southern Regional Council on Statistics (SRCOS)-National Science Foundation Travel
Grant, June 2012
MUSC Women's Club Scholarship, September 2011
Student Leadership Society Nominee, MUSC, 2012
Caitlyn Ellerbe
2012 MUSC Department of Medicine Research Day. Medical University of South
Carolina, Charleston, SC. 1st Place Award - Graduate Studies Division
Sarah Logan
Member- International Society for Autism Research (INSAR)
Member- Community Advisory Committee, of the International Society for Autism
Research
Member- Society for Clinical Trials
Member- Student Inter-Professional Society (SIPS)
Member- International Society for Pharmacoeconomics and Outcomes Research
(ISPOR)
154
Teaching Assistant for Foundations of Epidemiology, Fall 2011.
Completed training and serving as a Clinical Reviewer with the Centers for Disease
Control and Prevention’s (CDC) Autism and Developmental Disabilities Monitoring
(ADDM) Network, July 2011.
Nominated as Secretary for the International Society for Autism Research’s Community
Advisory Committee, August 2011.
Invited to serve on the National Advisory Board for the South Carolina Children’s
Educational Surveillance Study, January 2012.
Autism Speak’s Autism Awareness Month and Light it up Blue Campaign, Charleston
area contact and organizer, April 2012.
Invited to serve on the Planning and Content Committee for the Lowcountry Autism
Consortium, Charleston, SC. April 2012.
Tutor for Gross and Neuroanatomy, Summer 2012.
Travel Award for the global initiative Project Okurase in Ghana, West Africa, from the
Division of Education and Student Life, July 2012.
Anthony Parker
F31 NIH/NIDCR Fellowship for application entitled “Estimation of Periodontal Disease
Progression in the Presence of Diagnostic Error”
Dean Scholarship
Sybil Prince Nelson
First place - 2012 Student Research Day Poster in Health Disparities
Katherine Nicholas
Boyd Harshbarger Travel Award
James Small
Awarded the GAANN fellowship
Lee Wheless
Society for Investigative Dermatology PhD Retreat attendee
155
Department Accomplishments for 2011-2012
The 2011-2012 academic year was very productive for students in the graduate
program in Biostatistics and Epidemiology as we met most of the goals set last year.
We increased our average GRE scores. We had 37 applicants from which we
interviewed 15 students and offered admission to 10 students. Six of the 10 students
matriculated. One goal that was not met was to increase the number of students in the
epidemiology program. We continue to spend our efforts toward this, which we believe
could be better achieved when the Biostatistics and Epidemiology programs become
part of the new Department of Public Health Sciences.
This year our students published 31 manuscripts, many in high impact journals, and
presented 36 abstracts/posters at local, national, and international meetings. Several of
our students had their work recognized with competitive national and local awards,
travel awards, and fellowships. Our students also held trainee positions in our NIHsupported training program (BTBBR). Students participated on committees at the
university, college, department and community level, served as teaching assistants
beyond the requirement, tutored students in other areas, and also served as guest
lecturers in classes. Most importantly, one of our students received her PhD degree
during the year. Another one of our students completed the PhD portion of the MD/PhD
program at MUSC.
Department Goals for 2012-2013
The 2011-2012 academic year continued to offer both challenges and opportunities for
the graduate training program. The division revised and restructured the curriculum for
the explicit purpose of enhancing teaching efficiency, according opportunities to teach
so that faculty tenure portfolios are complete and generating revenue to support the
academic program of the division. We added one advanced inference course and an
introductory biology course. The opportunities of the new alignment come from
extensive research and collaborative activities that the Department of Medicine offers by
virtue of its size and the numerous funded activities that could potentially support PhD
candidates.
Student Recruitment
•
•
•
•
•
To maintain the number of applications to our program.
To maintain GRE score of applicants to our program.
To identify and increase applicants in epidemiology.
To reduce the number of accepted applicants who decline the offer.
To implement student recruitment data system including prospective student
pools and tracking system.
156
Current Students
•
•
•
•
•
•
To assign a mentor to students within the first year (100%).
To increase the percent of students completing the program within 5 years.
To maintain the number of student presentations at national meetings.
To increase student collaborative publications by at least 1 per year.
To increase the percent of students who have 3 first authored papers accepted
for publication before completion of their PhD.
To increase percent of graduates with academic faculty positions.
Graduate Training
•
•
•
To create a unified training program in biostatistics and epidemiology.
To revamp the epidemiology training program with emphasis on quantitative
methods and comparative clinical outcome research.
To engage trainees in a capstone program that fosters the application of
biostatistics and epidemiology across the various colleges and departments
within MUSC.
157
Department Of Cell And Molecular Pharmacology
Lauren Ball, Ph.D., Assistant Professor, Graduate Coordinator
Jennifer Isaacs, Ph.D., Assistant Professor, Graduate Coordinator
Student’s Name
Mentor
Degree Sought
Adnan Al-Ayoubi
Matriculation
Date
Fall 2005
Scott Eblen, Ph.D.
Amber Bradley
Fall 2009
Scott Eblen, Ph.D.
M.D., Ph.D.
(Dissertation
defended
01/2011)
Ph.D.
Krystal Dole
Fall 2010
Ph.D.
Thomas Powers
Fall 2011
Richard Drake, Ph.D.
Ph.D.
William Robichaux, III Fall 2010
Joe Blumer, Ph.D.
Ph.D.
Stephen Roper
Richard Drake, Ph.D.
Ph.D.
Fall 2010
STUDENTS’ PUBLICATIONS:
Manuscripts:
Wu S, Dole K, Hong F, Noman AS, Isaacs JS, Liu B, Li Z. gp96-independent inhibition
of endotoxin response by chaperone –based peptide inhibitors. J Biol. Chem. 2012, In
Press
Cooper, S.J., Tun, H.W., Roper, S.M., Kim, Y., Kilinger, T., Drake, R.R., and Copland,
J.A. Current Status of Biomarker Discovery in Human clear Cell Renal Cell Carcinoma.
J. Mol Biomark Diagn. 2012, S:2.
Abstracts
Bradley AT, Zheng H, Ziebarth A, Sakati W, Eier S, Lopez-Berestein G, Sood AK,
Landen CN Jr, Eblen ST. The E3 ubiquitin ligase EDD regulates platinum resistance
and is a novel therapeutic target for epithelial ovarian cancer. Hollings Cancer Center
Annual
Research
Retreat,
Daniel
Island,
SC,
November
18,
2011.
Bradley AT, Zheng H, Ziebarth A, Sakati W, Eier S, Lopez-Berestein G, Sood AK,
Landen CN Jr, Eblen ST. The E3 ubiquitin ligase EDD regulates platinum resistance
158
and is a novel therapeutic target for epithelial ovarian cancer. MUSC Annual Perry V.
Halushka Student Research Day, Charleston, SC, November 4, 2011.
Dole, K, Hance, M, Isaacs J. Extracellular Heat Shock Protein 90 (eHsp90) utilizes the
Polycomb epigenetic pathway to elicit EMT events in prostate cancer. MUSC Annual
Perry V. Halushka Student Research Day, Charleston, SC, November 4, 2011.
Roper, S.M., Lance, R.S., Kim, W.K., and Drake, R.R. Flow Cytometric Detection of
Macrophages from Expressed Prostatic Secretions. Hollings Cancer Center Retreat,
Charleston,
SC,
November
18,
2011.
Drake, R.R., Roper, S.M., Jones, E.E., Kraft, A.S., and Zemskova, M. Isolation of
Secreted Glycoproteins using Sugar-Azide Labeling and Alkyne-Bead Capture.
Jones, E.E., Roper, S.M., Nyalwidhe, J., Lance, R.S., Semmes, O.J., and Drake, R.R.
Exosomal Proteins from Benign and Prostate Cancer Proximal Fluids as Potential
Biomarkers. American Society for Mass Spectrometry, Vancouver, BC, May 21-25,
2012.
Dole K
First Prize: MUSC Annual Perry V. Halushka Student Research Day, Charleston, SC,
November 2011.
• During the fall, the Graduate coordinators hosted a celebration in honor of the
students. This event was well attended by faculty, postdoctoral fellows, students and
staff in the pharmacology department. We plan to host this event on an annual basis.
• The Principles of Pharmacology course PCOL 721 was offered this fall under the
direction of Lauren Ball, Joe Blumer and Jennifer Isaacs. Modest alterations were
made to the course based on student feedback from the previous year. Six students
took the course and all gave very positive reviews and confirmed that they would
recommend the class to future students.
• The eight week elective, Drug Discovery and Molecular Pharmacology PCOL 724,
was taught this spring in conjunction with Pharmaceutical Sciences.
• The format of the written qualifying examinations was changed from closed to open
book.
•
•
The courses being offered next year include: Principles of Pharmacology; Medical
and Dental Physiology; Dental Pharmacology.
Provide pharmacology graduate students with a human physiology course in the fall
as an alternative to taking the physiology component of the first year medical
159
•
•
•
•
curriculum.
Development of a short course on Mass Spectrometry and Proteomics.
The Pharmacology faculty will continue to contribute to the First Year Graduate
Curriculum units “Proteins” and “Receptors and Signaling” directed by Scott Eblen
and Steve Rosenzweig, respectively.
The Departmental website and recruitment brochures are currently being updated.
Find new ways to recruit bright students into our program.
160
Department of Drug Discovery and Biomedical Sciences
Patrick M. Woster, Ph.D., Graduate Coordinator
Student’s Name
Appleton, Kathryn
Bigham, Kevin
Matriculation
Date
2011
2008
Mentor
Degree Sought
Ph.D.
Ph.D.
Blakely, Jennifer
Eaddy, Andre
2007
2004
Yuri Peterson/Louis Lutrell
Yuri Peterson/Charles
Smith
Craig Beeson
Rick Schnellmann
Funk, Jason
2007
Rick Schnellmann
Gao, Peng
2007
Charles Smith
Garrett, Sara
Harris, Corbin
Hu, Jiangting
Hung, Hsin-I (Cindy)
Jesinky, Sean
2009
2009
2011
2008
2009
Rick Schnellmann
Patrick M. Woster
John Lemasters
Anna-Lisa Niemenen
Rick Schnellmann/ Craig
Beeson
James Chou/ Xuejun Wen
Craig Beeson
Chuck Smith
Patrick M. Woster
Josey, Benjamin
Leonard, Anthony
Lewis, Clay
Li, Youxuan
2009
2007
2009
Wayne State
2008 MUSC
2011
Saunders, Janet
2008
Schwartz, Justin
Smith, Matt
2008
2007
Sokolosky, Melissa
Trager, Nicole
2011
2008
Trager, Richard
2009
Whitaker, Ryan
2008
Craig Beeson/ Rick
Schnellmann
John Lemasters
Rick Schnellmann
Patrick M. Woster
Craig Beeson
Naren Banik
Rick Schnellmann
Yuri Peterson
Rick Schnellmann
161
M.D./Ph.D.
M.D./Ph.D.
(completed 2012)
Ph.D. (completed
2012)
Ph.D. (completed
2011)
Ph.D.
Pharm.D./Ph.D.
Ph.D.
Ph.D.
Pharm.D./Ph.D.
Ph.D.
Ph.D.
Ph.D.
Ph.D.
Ph.D.
Ph.D.
Ph.D. (completed
2012)
Ph.D.
Ph.D.
Ph.D.
M.D./Ph.D.
Journals
Appleton,
K.M.;
Cushman,
I.;
Peterson,
Y.K.:
Isoprenylcysteine
carboxymethyltransferase. Encyclopedia of Signaling Molecules, 2012, in press.
Appleton, K.M.; Lee, M.H.; Alele, C.; Luttrell, D.K.; Peterson, Y.K., Morinelli, T.A.;
Luttrell, L.M.: Biasing the parathyroid receptor: Relating in vitro ligand efficacy to in vivo
biological activity. Methods in Enzymology, 2012, in press.
Eaddy A.C., Cummings B, McHowat J, Schnellmann R.G.: The role of endoplasmic
reticulum Ca2+-independent phospholipase A2γ in oxidant-induced lipid peroxidation,
Ca2+ release, and renal cell death. Toxicol. Sci. 2012, epub ahead of print.
Eaddy, A.C., Schnellmann, R.G.: Visualization and quantification of endoplasmic
reticulum Ca2+ in renal cells using confocal microscopy and Fluo5F. Biochem. Biophys.
Res. Comm. 2011, 404, 424-427.
Funk, J.A.; Schnellmann, R.G.: Persistent disruption of mitochondrial homeostasis after
acute kidney injury. Am. J. Physiol. Renal Physiol. 2012, 302, F853-F864.
Gao, P.: Smith, C.D.: Ablation of sphingosine kinase 2 inhibits tumor cell proliferation
and migration. Mol. Cancer Res. 2011, 9, 1509-1519.
Saggu, S.; Hung, H-I.; Quiogue, G.; Lemasters, J.J., Niemenen, A-L.: Lysosomal
signaling enhances mitochondria-mediated photodynamic therapy in A431 cancer cells:
role of iron. Photochem. Biol. 2012, 88, 461-468.
Inks, E.S.; Josey, B.J.; Jesinky, S.R., Chou, C.J.: A novel class of small molecule
inhibitors of HDAC6. ACS Che. Biol. 2012, 7, 331-339.
Shi, Y.J.; Rehman, H.; Ramshesh, V.K.; Schwartz, J.; Liu, Q.; Krishnasamy, Y.; Zhang,
X.; Lemasters, J.J.: Sphingosine kinas 2 inhibition improved mitochondrial function and
survival after hepatic ischemia-reperfusion. Hepatology, 2012, 56, 137-145.
Smith, M.A.; McInnes, C.; Whitaker, R.M.; Lindsey, C.C.; Comer, R.F.; Beeson, C.C.;
Schnellmann, R.G.: Calpain 10 homology modeling with CYGAK and increased
lipophilicity leads to greater potency and efficacy in cells. ACS Chem. Biol. 2012, epub
ahead of print.
Smith M.A.; Schnellmann, R.G.: Calpains, mitochondria and apoptosis. Cardiovascular
Res. 2012, epub ahead of print.
162
Smith, M.A.; Covington, M.D.; Schnellmann, R.G.: Loss of calpain 10 causes
mitochondrial dysfunction during chronic hyperglycemia. Arch. Biochem. Biophys. 2012,
523, 161-168.
Smith M.A.; Schnellmann, R.G.: Mitochondrial calpain 10 degraded by Lon protease
after oxidant injury. Arch. Biochem. Biophys. 2012, 517, 144-152.
Sokolosky, M.L.; Stadelman, K.M.; Chappell, W.H.; Abrams, S.L.; Martelli, A.M.;
Stivala, F.; Libra, M.: Involvement of Akt-1 and mTOR in sensitivity of breast cancer to
targeted therapy. Oncotarget. 2011, 2, 538-550.
Sokolosky, M.L.; Wargovich, M.J.: Homeostatic inbalance and colon cancer: the
dynamic epigenetic interplay of imflammation, environmental toxins and
chemopreventative plant compounds. Front. Oncol. 2012, in press.
Wills, L.P.; Trager, R.E.; Beeson, G.C.; Lindsey, C.C.; Peterson, Y.K.; Beeson C.C.;
Schnellmann R.G.: The β2-adrenoceptor agonist formoterol stimulates mitochondrial
biogenesis. J. Pharm. Exp. Ther. 2012, 342, 106-118.
Abstracts
Kevin Bigham, Ellen Maher, Starr Hazard, Joe Blumer and Yuri Peterson Selective
small molecule inhibitors of heterotrimeric G-protein signaling for the treatment of
ovarian cancer. April 9-13, 2011 Experimental Biology, Walter E. Washington
Convention Center, Washington D.C.
Kevin Bigham, Ellen Maher, Starr Hazard, Joe Blumer and Yuri Peterson: Selective
small molecule inhibitors of heterotrimeric G-protein signaling for the treatment of
ovarian cancer. April 13-14, 2011, RGS & AGS Proteins in Physiology & Disease
Colloquium, Washington, D.C.
Kevin Bigham, Starr Hazard, Jonel Lirjoni, Ellen Maher, Joe Blumer and Yuri K.
Peterson: Selective small molecule inhibitors of heterotrimeric G-protein signaling for
the treatment of ovarian cancer. November 5, 2011, 46th Annual Perry V. Halushka
MUSC Student Research Day, Charleston, S.C.
Kevin Bigham, Starr Hazard, Jonel Lirjoni, Ellen Maher, Joe Blumer and Yuri K.
Peterson: Development of selective small molecule inhibitors of heterotrimeric G-protein
signaling for the treatment of ovarian cancer. November 18, 2011 Hollings Cancer
Center 11th Annual Scientific Research Retreat, Charleston, SC.
Blakely, J.L.; Garrett, S.M.; Beeson, C.C.; Schnellmann, R.G.: %-Hydroxytryptamine
class 2 receptor-mediated mitochondrial biogenesis as a potential therapeutic strategy
for treatment of acute kidney injury. American Society of Nephrology Kidney Week,
2012.
163
Josey, B.J.; Wen, X.; Chou, C.J.: Structure-activity relationship study of the
neuroprotective effects of vitamin K derivatives yields potent neuroprotective
compounds. American Chemical Society National Meeting, San Diego, CA, March 25,
2012.
Leonard, A.P., Perron, N., Nasarre, C., Beeson, C., Rohrer, B. May 2011.
Mitochondrial fusion is linked to bioenergetic capacity and cell survival in a cell-based
model of PDE6b-dependent RP, Association for Research in Vision and Ophthalmology
(ARVO)– poster presentation, Fort Lauderdale, FL
Leonard, A.P., Perron, N., Nasarre, C., Beeson, C., Rohrer, B. July 2011. Inhibition of
Mitochondrial Fission is Associated with Neuroprotection in Retinitis Pigmentosa,
National MD/PhD Student Conference-poster presentation, Keystone, CO
Leonard, A.P., Peterson YK, Perron NR, Beeson CC, Rohrer BM. March 2012. High
Content Imaging-based Automated Classification of Mitochondrial Morphology. Abstract
for oral presentation, Medical University of South Carolina 22nd Annual MSTP Research
Day. Charleston, SC.
Leonard, A.P., Peterson YK, Perron NR, Beeson CC, Rohrer BM. March 2012. High
Content Imaging Analysis of Mitochondrial Morphology in Retinal Degeneration.
Frontiers in Neuroscience Conference-poster presentation, Seabrook Island, SC
Leonard, A.P., Peterson YK, Perron NR, Beeson CC, Rohrer BM. May 2012. High
Content Imaging Reveals Mitochondrial Morphological Insights into the Mechanism of
Neuroprotective Drug Candidates in Retinitis Pigmentosa. National Clinical and
Translational Sciences Predoctoral Meeting, Mayo Clinic, Rochester, MN.
Saunders, J.E.; Beesom, C.C.; Schnellmann, R.G.: Disruption of mitochondrial
homeostasis and subpopulations in aged mice. Keystone Mitochondrial Dynamics and
Function Symposium, 2012.
Schwartz, J.; Zhang, X.; Lovelace, G.L.; Lemasters, J.J.: Minocycline and doxycycline
cytoprotect by inhibition of the mitochondrial calcium uniporter and not by other
mechanisms. 51st Annual Society of Toxicology Meeting, 2012.
Presentations
Kevin Bigham, Ellen Maher, Starr Hazard, Joe Blumer, and Yuri Peterson:
Development of selective small molecule inhibitors of heterotrimeric G-protein signaling
for the treatment of ovarian cancer. September 23, 2011 2nd Annual Pharmaceutical
and Biomedical Sciences Graduate Student Retreat, Medical University of South
164
Blakely, J.L.: Exploring 5HT2c-mediatedmitochondrial biogenesis as a potential
therapeutic for the treatment of acute kidney injury. MSTP Research Day, March 24,
2012, MUSC.
Josey, B.J.: Novel HDAC6/Hsp90 complex inhibitors for the treatment of acute myeloid
leukemia. Hollings Cancer Center Retreat, November 18, 2011.
Leonard, A.P.: Inhibition of mitochondrial fission is associated with neuroprotection in
retinitis pigmentosa. SCCP Graduate Student Retreat, May 20, 2011.
Li, Y.: Design, synthesis and bioevaluation of novel polyamine-based histone
deacetyalse inhibitors. South Carolina College of Pharmacy Graduate Retreat,
September 23, 2011
Kevin Bigham: Finalist: Best Abstract Award − American Society for Pharmacology and
Experimental Therapeutics (ASPET), Molecular Pharmacology Division.
Kevin Bigham: Graduate Student Travel Award − American Society for Pharmacology
and Experimental Therapeutics (ASPET).
Sara Garrett: Awarded a research assistantship from the T32 Research Training
Program on Bioenergetics, Oxidative Stress and Metabolic Syndromes.
Sean Jesinky: Awarded NHLBI Training Fellowship “#HL007260 - Training to Improve
Cardiovascular Therapies.”
Benjamin Josey: Student Travel Award, Division of Medicinal Chemistry, American
Chemical Society National Meeting, San Diego, CA, March 25, 2012.
Benjamin Josey: Awarded NHLBI Training Fellowship “#HL007260 - Training to
Improve Cardiovascular Therapies.”
Anthony Leonard: Received a Diversity Travel Award for the National MD/PhD Student
Meeting, Keystone, CO 2011.
Clayton Lewis: Department of Biomedical and Pharmaceutical Sciences Graduate
Student Retreat, First Place in Oral Presentations.
Justin Schwartz: Presidential Scholar award, Medical University of South Carolina,
2011.
165
Successful completion of dissertation defense: Dr. Peng Gao (Smith), Dr. Andre
Eaddy (Schnellmann), Dr. Jason Funk (Schnellmann) and Dr. Matt Smith
(Schnellmann).
Patrick M. Woster, Ph.D., assumes role as Graduate Coordinator for Pharmaceutical
and Biomedical Sciences July 1, 2011.
Strategic plan for department approved by the faculty August 16, 2011.
Department approves name change to Drug Discovery and Biomedical Sciences;
approved by MUSC Board of Trustees April 13, 2012.
Department awarded South Carolina COBRE Grant in Oxidants, Redox and Stress
Signalling ($7,484,062 total direct costs) March, 2012.
Two tuition scholarships provided by the SCCP MUSC Campus Dean were created and
awarded to Megan Dupperreault and Meredith Kaywood.
The departmental graduate requirements document has been edited to comply with
COGS requirements and posted: (http://wizard.musc.edu/gradrequirements_musc.html;
the requirements for department grad students on the USC campus were also edited
and posted (http://wizard.musc.edu/gradrequirements_usc.html). The MUSC document
features links to the COGS web site and to the first year curriculum.
Web pages for department faculty on both the MUSC and USC campuses are being
updated to reflect research interests, and to facilitate recruitment.
PBS recruited 2 students from the 2011-2012 1st year class: Melissa Sokolosky
(Woster) and Jiangting Hu (Lemasters), one transfer student, Youxuan Li (Woster) one
PharmD./Ph.D. student, Corbin Harris (Woster) and a verbal commitment from one
M.D./Ph.D. student, Craig Kutz (Woster). Steven Holshouser also joined the department
as a 1st year grad student (Woster).
PBS produced 4 Ph.D. graduates during 2011-2012 (Peng Gao, Matt Smith, Andre
Eaddy, Jason Funk).
Department/Program Goals for 2012-2013
As graduate coordinator, I will work with students to ensure that graduate progression
follows the prescribed timeline, and that milestones in the Ph.D. program are reported to
the COGS in a timely fashion. All students will be brought up to date with regard to their
requirements.
166
We will continue to integrate graduate courses offered by our combined department
(MUSC and USC) through the South Carolina College of Pharmacy, and will work to
increase interaction among graduate students on the two campuses.
We will work to enhance the Pharm.D./Ph.D. Program with additional tuition and/or
stipend support for the didactic Pharm.D. period, with additional courses, and with
program-specific oversight and mentoring.
In conjunction with the COGS, we will use the internet and other means of
communication to enhance our recruitment efforts, with the goal of increasing the
number of students in our Ph.D. and Pharm.D./Ph.D. programs.
Using similar methods, we will attempt to increase the number of students taking
courses offered by the Department of Drug Discovery and Biomedical Sciences.
We will work to increase the number of students presenting their research at regional
and national scientific meetings, and will seek travel grant funding whenever possible.
All students will be encouraged to publish their results, and thus we will increase the
number of peer-reviewed manuscripts authored by students and postdoctoral
associates.
All students will be encouraged to present their results, and thus we will increase the
number of posters and oral presentations given by students.
167
Dr. Laura M. Kasman, Graduate Coordinator
Student’s Name
Akerman, Adam
Almadani, Abdul
Basher, Fahmin
Beckham, Thomas
Bergman, Charles
Brandon, Danielle
Buie, Joy Jones
Casey, Sarah
Cheng, Joseph
Clark, Danielle
Coughlin, Beth
DeCosta, Anna-Maria
DePalma, Telma M
Deepe, Raymond
Coughlin, Beth
Elvington, Andrew
Hathaway, Jessica
Johnson, C. Bryce
Justis, Danielle
Karam, Eva
Little, Elizabeth
Marrison, S. Tucker
Marshall, Christopher
Mashmoushi, Ahmad
Midgett, Kristin
Morales, Crystal
Morris, Keely
Rachidi, Saleh
Rodriguez, Kristoffer
Scheffel, Matthew
Scott, Jennifer L.
Sutter, Alton
Trager, Nicole
Matriculation
Date
2010
2011
2008
2009
2011
2011
2009
2010
2005
2009
2011
2006
2008
2009
2011
2007
2011
2009
2011
2011
2006
2008
2006
2007
2009
2010
2006
2010
2011
2010
2009
2007
2008
Mentor
Dr. Jeffrey Jones
Dr. Azizul Haque
Dr. Tamara Nowling
Dr. James Norris
Dr. Kenneth Chavin
Dr. John Zhang
Dr. James Oates
Dr. Carl Atkinson
Dr. Jim Norris
Drs. I. Singh & Doe Jenkins
Dr. Barb Rohrer
Dr. M. Rita Young
Dr. Mike Nishimura
Dr. Pandey
Dr. Barb Rohrer
Dr. Steve Tomlinson
Dr. Azizul Haque
Dr. David Cole
Dr. Rita Young
Dr. John Zhang
Dr. David Cole
Dr. James Norris
Dr. Hal May
Dr. Gary Gilkeson
Dr. Diane Kamen
Dr. Zihai Li
Dr. Steve Tomlinson
Dr. Zihai Li
Dr. Carl Atkinson
Dr. Christina Voelkel-Johnson
Dr. Gary Gilkeson
Dr. Kenneth Chavin
Dr. Naren Banik & Dr. Craig
Beeson
168
Degree
Sought
Masters
Masters
M.D./Ph.D.
M.D./Ph.D.
Masters
Masters
Ph.D.
Ph.D.
M.D./Ph.D.
M.D./Ph.D.
Masters
M.D./Ph.D.
Ph.D.
Masters
Masters
Ph.D.
Ph.D.
M.D./Ph.D.
Masters
Masters
Ph.D.
M.D./Ph.D.
Ph.D.
M.D./Ph.D.
Ph.D.
Visiting Ph.D.
M.D./Ph.D.
M.D./Ph.D.
Masters
Masters
M.D./Ph.D.
M.D./Ph.D.
Ph.D.
Journals
cathepsin B. Int J Cancer Feb 9, 2012. (doi: 10.1002/ijc.27480) [Epub ahead of print]
Cheng JC, Bai A, Beckham TH, Marrison ST, Yount CL, Lyons K, Jones EE, Wu BX,
Keane BJ, Armeson KE, Marshall DT, Keane TE, Smith MT, Drake RR, Bielawska A,
Norris JS, Liu X. Radiation-induced acid ceramidase upregulation confers resistance
and tumor relapse. In submission, 2012.
Rohrer B, Coughlin B, Bandyopadhyay M, Holers VM. Systemic human CR2-targeted
complement alternative pathway inhibitor ameliorates mouse laser-induced choroidal
neovascularization. Journal of Ocular Pharmacology and Therapeutics, Feb 6, 2012.
Deepe RN, Kistner-Griffin E, Martin JN, Deeks SG, Pandey JP. Epistatic interactions
between Fc (GM) and FcγR genes and the host control of human immunodeficiency
virus replication. Hum Immunol. 2012 Mar;73(3):263-6. Epub 2011 Dec 11. PMID:
22213007
Elvington A, Atkinson C, Kulik L, Zhu H, Yu J, Kindy MS, Holers VM, Tomlinson S.
Pathogenic natural antibodies propagate cerebral injury following ischemic stroke in
mice. J Immunol 188(3):1460-8, 2012. PMID: 22198950 (selected as an "in this issue"
manuscript (top 10% in J Immunol).
De Costa AM, Schuyler CA, Walker DD, Young MR. Characterization of the evolution of
carcinoma of the head and neck. Cancer Immunol Immunother. 2012 Jun;61(6):927-39.
Epub 2011 Nov 25. PMID: 22116344
De Costa AM, Justis DN, Schuyler CA, Young MR. Administration of a vaccine
composed of dendritic cells pulsed with premalignant oral lesion lysate to mice bearing
carcinogen-induced premalignant oral lesions stimulates a protective immune response.
Int Immunopharmacol. 2012 May 15. [Epub ahead of print] PMID: 22609090
Walker DD, Reeves TD, de Costa AM, Schuyler C, Young MR. Immunological
modulation by 1α,25-dihydroxyvitamin D(3) in patients with squamous cell carcinoma of
the head and neck. Cytokine. 2012 Jun;58(3):448-54. Epub 2012 Mar 24. PMID:
22450225
Schepp-Berglind J, Atkinson C, Elvington M, Qiao F, Mannon P, Tomlinson S.
Complement-Dependent Injury and Protection in a Murine Model of Acute Dextran
169
Sulfate Sodium-Induced Colitis. J Immunol. 2012 May 7. [Epub ahead of print]
Elvington M, Huang Y, Morgan BP, Qiao F, van Rooijen N, Atkinson C, Tomlinson S. A
targeted complement-dependent strategy to improve the outcome of mAb therapy, and
characterization in a murine model of metastatic cancer. Blood. 2012 Mar 22. [Epub
ahead of print]
Elvington A, Atkinson C, Kulik L, Zhu H, Yu J, Kindy MS, Holers VM, Tomlinson S.
Pathogenic natural antibodies propagate cerebral injury following ischemic stroke in
mice. J Immunol. 2012 Feb 1;188(3):1460-8. Epub 2011 Dec 23.PMID: 22198950
Ayers CM, Schlosser RJ, O'Connell BP, Atkinson C, Mulligan RM, Casey SE, Bleier BS,
Wang EW, Sansoni ER, Kuhlen JL, Mulligan JK. Increased presence of dendritic cells
and dendritic cell chemokines in the sinus mucosa of chronic rhinosinusitis with nasal
polyps and allergic fungal rhinosinusitis. Int Forum Allergy Rhinol. 2011 JulAug;1(4):296-302. doi: 10.1002/alr.20046. PMID: 22287435
Rubinstein MP, Cloud CA, Garrett TE, Moore CJ, Schwartz KM, Johnson CB, Craig
DH, Salem ML, Paulos CM, Cole DJ. Ex vivo interleukin-12-priming during CD8(+) T
cell activation dramatically improves adoptive T cell transfer antitumor efficacy in a
lymphodepleted host. J Am Coll Surg 214(4):700-8, 2012.
Johnson CB, Tikunov AP, Lee H, Wolak JE, Pediaditakis P, Romney DA,
Holmuhamedov E, Gamcsik MP, Macdonald JM.
13 C magnetic resonance
spectroscopy detection of changes in serine isotopomers reflects changes in
mitochondrial redox status. Magn Reson Med 2011 (doi: 10.1002/mrm.23296).
Evans ZP, Palanisamy AP, Sutter AG, Ellett JD, Ramshesh VK, Attaway H, Schmidt
MG, Schnellmann RG, Chavin KD. Mitochondrial uncoupling protein-2 deficiency
protects steatotic mouse hepatocytes from hypoxia/reoxygenation. Am J Physiol
Gastrointest Liver Physiol 302(3):G336-42, 2012. (Epub Nov 17, 2011)
Murshed M, Cevik MO, Ogretmen B. Off-Target Function of the Sonic Hedgehog
Inhibitor Cyclopamine in Mediating Apoptosis via Nitric Oxide-Dependent Neutral
Sphingomyelinase 2/Ceramide Induction. Mol Cancer Ther. 2012 May;11(5):1092-102.
Epub 2012 Mar 27.
Little EC, Wang C, Watson PM, Watson DK, Cole DJ, Camp ER. Novel
Immunocompetent Murine Models Representing Advanced Local and Metastatic
Pancreatic Cancer. J Surg Res. 2011 Nov 10. [Epub ahead of print]
PMID: 22221605
Kaur N, Naga OS, Norell H, Al-Khami AA, Scheffel MJ, Chakraborty NG, VoelkelJohnson C, Mukherji B, Mehrotra S. T cells expanded in presence of IL-15 exhibit
170
increased antioxidant capacity and innate effector molecules. Cytokine. 2011
Aug;55(2):307-17. Epub 2011 May 23. PMID: 21602054
Abstracts
Johnson CB, Cloud CA, Rubinstein MP, Cole DJ. “Total body irradiation enhances the
anti-tumor efficacy of adoptively transferred CD8+ T cells stimulated ex vivo with IL-12,”
American Association of Immunologists, Boston, MA, May 2012.
Johnson CB, Cloud CA, Rubinstein MP, Cole DJ. “Total body irradiation enhances the
anti-tumor efficacy of adoptively transferred CD8+ T cells stimulated ex vivo with IL-12,”
Hollings Cancer Center Research Retreat, Charleston, SC, March 2012.
Katikaneni L, Mulvihill DM, Johnson CB, Perkel J, Lambert D, Morgan P, Brown T,
Chang E, Caplan M & Jenkins D. “Brain biomarkers for the development of motor injury
in term newborns exposed to chorioamnionitis,” International Society for Developmental
Neuroscience Annual Meeting, Mumbai, India, January 2012.
S Tucker Marrison, Joseph C Cheng, Thomas H Beckham, Ping Lu, Xiang Liu,
James S Norris. “Sphingosine 1-phosphate receptor signaling in mesenchymal stem
cells,” MSTP Student Research Day Spring 2012.
Sarah T Marrison, Joseph C Cheng, Thomas H Beckham, Ping Lu , Angen Liu,
Sarah Casey, Xiang Liu, James S Norris. “Acid ceramidase over expression in
response to cigarette smoke exposure,” MUSC Student Research Day Fall 2011.
Marrison Sarah T, Cheng Joseph C, Beckham Thomas H, Lu Ping, Casey Sarah,
Liu Angen, Liu Xiang, Norris James S. “Acid ceramidase over expression in response
to cigarette smoke exposure,” Hollings Cancer Center Retreat Fall 2011.
Matthew Scheffel (Abstract and Poster Presentation). “Activation-induced cell-death of
adoptively transferred T-cells for the immunotherapy of melanoma,” Student Research
Matthew Scheffel (Abstract and Poster Presentation). “Activation-induced cell-death of
adoptively transferred T-cells for the immunotherapy of melanoma,” Hollings Cancer
Center Retreat, November 18, 2011.
Presentations
Kristin Midgett, “Effects of perfluorooctanesulfonic acid (PFOS) and perfluorooctanoic
acid (PFOA) on IL-2 production in the human jurkat T-cell line,” 51st Society of
Toxicology Conference in San Francisco, CA, 2012.
171
Bryce Johnson, MUSC Hollings Cancer Center Abney Foundation Scholarship, 2011.
Kristin Midgett, 2011-2012 Presidential Scholar.
Kristin Midgett, 2011-2012 SCTR TL1 Trainee.
Eva Karam, 2nd place poster, 2011 Perry Halushka Student Research Day, Clinical-
Professional Masters Poster Division III
Danielle N. Justis 2nd place poster, 2011 Perry Halushka Student Research Day,
PhD Poster Division I
•
•
•
•
•
•
Degrees conferred: The Microbiology and Immunology Program conferred 5
Ph.D.s (Anna-Maria De Costa, Michael Defee, Telma M. DePalma, Joseph C.
Cheng, Michelle Rapisardo (Elvington)) and 1 Masters degree (Raymond Deepe)
in the year ending June 30, 2012.
A T32 Training Grant application entitled “Molecular and Cellular Basis of
Inflammation and Immunity.” Was submitted. Stephen Tomlinson, PI.
A Certificate of Biomedical Sciences Program was developed by M&I faculty and
enrolled its first 8 students in May 2012
A distance learning component was implemented as part of the Certificate
Program.
Of the 8 students that have entered our Masters program and graduated in the
past three years (Casey, Doonan, Dunmyer, Hathaway, Johnson, Norton, ReyesCortes, and Deepe) 3 have been accepted to PhD programs, 3 to medical
schools of their choice, and 2 are currently employed in research. One other
masters student was accepted to the PhD program without finishing his masters
degree.
A refereed journal club for credit was approved by the CGS curriculum committee
and made mandatory for all PhD candidates in the department.
•
•
•
•
To continue to update and improve our webpage.
To continue working on a collection of key core knowledge facts in microbiology
and immunology that would be required knowledge of all M&I graduates from
memory
Increase the rigor of our student and faculty seminar course.
To expand the Certificate in Biomedical Sciences Program to 20 students in the
2013-2014 school year.
172
Antonieta Lavin, PhD, Graduate Coordinator
Student’s Name
Joshua Swearingen
Joseph Taylor
Aram Parsegian
Bok Sun Go
Matriculation Date
2006/FA
2007/FA
2007/FA
2008/FA
Natasha New
2009/FA
Zachary Cope
2008/FA
Jacob Beckley
Brandon Bentzley 2008 /FA
2009/FA
Michael Stefanik
Noam Keren
2009/FA
2010/FA
Kathryn Spencer
2010/FA
Brittney Marie Cox
2010/FA
Benjamin Hughes
Joshua Smith
William Buchta
Sarah Barry
2010/FA
2010/FA
2011/FA
2011/FA
Ellen McGlinchey
2011/FA
Sarah Corrin Barrett
2011/FA
April Cox
Alexander W Smith
Samuel Centanni
2011/FA
2011/FA
2011/FA
Mentor
Dr. Jane Joseph
Dr. Mark George
Dr. Ron See
Dr. Jacqueline
McGinty
Dr. L. Judson
Chandler
Dr. Gary AstonJones
Dr. John Woodward
Dr. Gary AstonJones
Dr. Peter Kalivas
Dr. Gary AstonJones
Dr. L. Judson
Chandler
Dr. Ron See/
Dr. Gary AstonJones
Dr. John Woodward
Dr. Naren Banik
Dr. Arthur Riegel
Dr. Jacqueline
McGinty
Dr. Gary AstonJones
Dr. Heather
Trantham-Davidson/
Dr. L. Judson
Chandler
Dr. Naren Banik
Dr. Peter Kalivas
Dr. Heather
Trantham-Davidson/
Dr. L. Judson
Chandler
173
Degree Sought
PhD
MD/PhD
PhD
PhD
PhD
PhD
PhD
MD/PhD
PhD
PhD
PhD
PhD
PhD
MD/PhD
PhD
PhD
PhD
PhD
PhD
PhD
PhD
STUDENTS PUBLICATIONS
Journals
Beckley JT, Woodward JJ (2011). The abused inhalant toluene differentially modulates
excitatory and inhibitory synaptic transmission in deep-layer neurons of the medial
prefrontal cortex. Neuropsychopharmacology, 36(7):1531-42:
Bentzley, B., Fender, K., Aston-Jones, G. (2012). Behavioral economics for the
neuroscientist: A review and new analytical approach. Psychopharmacology. [In
Review].
Cox ,B, Mrudang M. Shah, Matthew P. Galloway, David M. Thomas, and Shane A.
Perrine. (2012) MDMA induces aversive and anxiety-like behavior and increases
amygdalar serotonin of adolescent rats. Submitted
Mahler,SV, Feltenstein, MW, Moorman, DE, Cox,BM, Ogburn, K, Bachar M,
McGonigal, J,. See., RS (2012) “Self-Report” Measure of Methamphetamine Craving?
Rat
Ultrasonic
Vocalizations
in
Self-Administration,
Extinction,
and
Reinstatement.Submitted
Cox,BM, Alsawah F, McNeill P, GallowayMP, Perrine, SA. (2011). Neurochemical,
hormonal, and behavioral effects of chronic unpredictable stress in the rat. Behav Brain
Res, 220(1), 106-111
Diaz, M.R., Wadleigh, A., Hughes, B.A., Woodward, J.J., & Valenzuela, C.F. (2011).
Bestrophin1 channels are insensitive to ethanol and do not mediate tonic GABAergic
currents in cerebellar granule cells. Frontiers in Neuropharmacology 5: 148.
Kuchinsky, S.E., Vaden, K.I., Keren, N.I., Harris, K.C., Ahlstrom, J.B., Dubno, J.R., &
Eckert, M.A. (2011). Word intelligibility and age predict visual cortex activity during word
listening. Cerebral Cortex
Vaden, K.I., Kuchinsky, S.E., Keren, N.I., Harris, K.C., Ahlstrom, J.B., Dubno, J.R., &
Eckert, M.A. (2011). Inferior frontal sensitivity to common speech sounds is amplified by
increasing word intelligibility. Neuropsychologia, 49 (13), 3563-72.
Eckert, M.A., Keren, N.I., Roberts, D.R., Calhoun, V.D., & Harris, K.C. (2010). Agerelated changes in processing speed: unique contributions of cerebellar and prefrontal
cortex. Frontiers in Human Neuroscience, 4, 1-10
Kroener S, Mulholland P, New N, Gass T, Becker H, Chandler LJ .(2012) Chronic
alcohol exposure alters behavioral and synaptic plasticity of the rodent prefrontal cortex.
PLoS ONE. Accepted
174
Parsegian A., Glen WB., Lavin A., See RE., (2011) Methamphetamine selfadministration produces attentional set-shifting deficits and alters prefrontal cortical
neurophysiology in rats. Biol Psych 69(3):253-259
Stefanik, M.T., Moussawi, K., Kupchik, Y.M., Smith, K.C., Miller, R.L., Huff, M.L.,
Deisseroth, K., Kalivas,
P.W., LaLumiere, R.T. Optogenetic inhibition of cocaine
seeking in rats. Addiction Biology. (submitted)
Park S, Nozaki K, Guyton MK, Smith JA, Ray SK, Banik NL. (2012) Calpain Inhibition
Attenuated Morphological and Molecular Changes in Skeletal Muscle of Experimental
Allergic Encephalomyelitis Rats. J Neurosci Res. In press
Haar CP, Hebbar P, Wallace GCt, Das A, Vandergrift WA, 3rd, Smith JA, et al. (2012)
Drug resistance in glioblastoma: a mini review. Neurochem Res. 37(6):1192-200.
Smith JA, Das A, Ray SK, Banik NL. (2012) Role of pro-inflammatory cytokines
released from microglia in neurodegenerative diseases. Brain Res Bull. 87(1):10-20.
McDowell ML, Das A, Smith JA, Varma AK, Ray SK, Banik NL. (2011) Neuroprotective
effects of genistein in VSC4.1 motoneurons exposed to activated microglial cytokines.
Neurochem Int. 59(2):175-84. PMCID: 3153433.
Samantaray S, Smith JA, Das A, Matzelle DD, Varma AK, Ray SK, et al.(2011) Low
dose estrogen prevents neuronal degeneration and microglial reactivity in an acute
model of spinal cord injury: effect of dosing, route of administration, and therapy delay.
Neurochem Res. 36(10):1809-16. PMCID: 3162090.
Ray SK, Samantaray S, Smith JA, Matzelle DD, Das A, Banik NL. (2011) Inhibition of
cysteine proteases in acute and chronic spinal cord injury. Neurotherapeutics. 8(2):1806. PMCID: 3101838.
Das A, McDowell M, O'Dell CM, Busch ME, Smith JA, Ray SK, et al. (2010) Posttreatment with voltage-gated Na(+) channel blocker attenuates kainic acid-induced
apoptosis in rat primary hippocampal neurons. Neurochem Res. 35(12):2175-83.
Smith JA, Das A, Butler JT, Ray SK, Banik NL.(2011) Estrogen or estrogen receptor
agonist inhibits lipopolysaccharide induced microglial activation and death. Neurochem
Res. 36(9):1587-93.
Das A, Smith JA, Gibson C, Varma AK, Ray SK, Banik NL(2011). Estrogen receptor
agonists and estrogen attenuate TNF-alpha-induced apoptosis in VSC4.1 motoneurons.
J Endocrinol. 208(2):171-82.
Sribnick EA, Samantaray S, Das A, Smith J, Matzelle DD, Ray SK, et al. (2010)
Postinjury estrogen treatment of chronic spinal cord injury improves locomotor function
in rats. J Neurosci Res. 88(8):1738-50. PMCID: 3127445.
175
Das A, McDowell M, Pava MJ, Smith JA, Reiter RJ, Woodward JJ, et al. (2010) The
inhibition of apoptosis by melatonin in VSC4.1 motoneurons exposed to oxidative
stress, glutamate excitotoxicity, or TNF-alpha toxicity involves membrane melatonin
receptors. J Pineal Res. 48(2):157-69. PMCID: 2862889.
Smith JA, Zhang R, Varma AK, Das A, Ray SK, Banik NL. (2009) Estrogen partially
down-regulates PTEN to prevent apoptosis in VSC4.1 motoneurons following exposure
to IFN-gamma. Brain Res.1301:163-70. PMCID: 2784273.
Joseph JE, Swearingen J, Corbly CR, Curry Jr TE., Kelly TH (2012) Influence of
estradiol on functional brain organization for working memory, Neuroimage
Joseph JE, Clark JD, Swearingen J,. Bhatt RS, Benca CE, Collins HR, Corbly CR, and
Gathers AD, (2012) The changing landscape of functional brain networks for face
processing in typical development Submitted
Buhusi CV, Aziz D, Winslow D, Carter RE, Swearingen J and Buhusi MC (2009) ,
Interval timing accuracy and scalar timing in C57BL/6 mice. Behavioral Neuroscience,
5: 123
Swearingen, J.E. and Buhusi C.V. (2010) The Pattern of Responding in the PeakInterval Procedure: a Single Trials Analysis. Journal of Experimental Psychology:
Animal Behavior Processes
Taylor JJ, Borckardt JJ, George MS (2012) Endogenous Opioids Mediate Left
Dorsolateral Prefrontal Cortex rTMS-Induced Analgesia. Pain 153, 1219-1225.
Abstracts
Barrett, SC, Chandler J, Trantham-Davidson, H (2012) Developmental progression of
pyramidal neuron excitability and dopamine modulation in PFC. New Orleans SfN
(poster)
Beckley JT, Evins CE, Fedarovich G, Woodward JJ (2012). The medial prefrontal
cortex regulates toluene-induced enhancement of excitatory synaptic transmission in
mesoaccumbens core dopamine neurons. Society for Neuroscience Abstr. New
Orleans, LA.
Buchta W, Quattelbaum A, Harlan B, and Riegel A (2011) Plasticity of Prefrontal
Cortex Pyramidal Neurons after Multiple Cocaine Paradigms
Neuropalooza,
Charleston, SC
Buchta W, Harlan B, Kalivas P, and Riegel A (2012) Restoration of Neuronal Inhibition
in the Anterior PFC During Reinstatement to Cocaine Seeking by Targeting Inhibitory
KCNQ Ion Channels, SfN, New Orleans
176
Hughes H, Buchta W, Harlan B, Wang R, Quattelbaum A, Shippenberg T, and Riegel A
(2012) Chronic Pain Stimulates the dmPFC: Biomarkers to study the Affective
Component of Neuropathic Pain. Frontiers in Neuroscience Seabrook SC, 2012
Centanni, S, Chandler, LJ, Trantham-Davidson H (2011) Adolescent Ethanol Exposure
Alters Dopamine Modulation of Cortical Function in Adulthood NADIA Consortium SemiAnnual Meeting, Chapel Hill, NC
Centanni, S, Chandler, LJ, Trantham-Davidson H (2011) Chronic Intermittent Ethanol
Exposure Disrupts D2-receptor Modulation of Prefrontal Cortical Neurons Society for
Neuroscience, Washington, DC
Chandler, JL, Centanni, S, Trantham-Davidson, H ( 2012) Chronic Alcohol Disrupts
Cognitive Function and D2/D4 Receptor Modulation of Neuronal Firing in the Prefrontal
Cortex of the Rat American College of Neuropharmacology, Waikoloa Beach, HI
Centanni, S, Trantam-Davidson, H and Chandler JL (2012) Adolescent Ethanol
Exposure Reduces Adulthood COMT Levels in the Medial Prefrontal Cortex Research
Society on Alcoholism, San Francisco, CA
Centanni, S, Chandler, JL and Trantham-Davidson H ( 2012) Chronic Alcohol Exposure
Disrupts Cognitive Function and D2/D4 Receptor Modulation of Neuronal Firing in the
Rat Prefrontal Cortex Research Society on Alcoholism, San Francisco, CA
Cope, ZA, Vazey, E, Moorman, DE, Floresco, SB, Aston-Jones, GS. (2010)
Optogenetic modulation of locus coeruleus noradrenergic neurons: effects on setshifting. SfN Annual Meeting, San Diego, CA
Optogenetic and pharmacologic modulation of locus coeruleus noradrenergic neurons:
effects on behavioral flexibility. Submitted, SfN Annual Meeting, Washington D.C
Cope,
ZA,
Vazey,
E,
Moorman,
DE,
Floresco,
SB,
Aston-Jones,
GS(2012). Optogenetically Mediated Tonic Stimulation of Locus Coeruleus Improves
Maintenance of Novel Strategies On Extradimensional Shifts. Submitted, Elsevier
Opto- and Pharmacogenetics SfN Pre-conference, New Orleans.
Optogenetically Mediated Tonic Stimulation of Locus Coeruleus Improves Maintenance
of Novel Strategies On Extradimensional Shifts. Society for Neuroscience Annual
Meeting, New Orleans
177
Cox, BM, Cope ZA, Parsegian A, Moorman DE, Floresco SB, G. Aston-Jones G, See
RE. (2011) Automated attention set-shift task following methamphetamine selfadministration. Washington DC: Society for Neuroscience (poster).
Cox, BM Cope ZA, Parsegian A, Moorman DE, Floresco SB, Aston-Jones G, See RE
(2011) Assessing cognitive flexibility following methamphetamine self-administration
Medical University of South Carolina student research day, Charleston, SC (poster)
Cox,BM, Chan C, Ghee SM, See RE, Reichel CM (2012) . Oxytocin decreases
methamphetamine self-administration in female rats. College on Problems of Drug
Dependence,. California (poster)
Cox, BM, Chan C, Ghee SM, See RE, Reichel CM (2012) . Oxytocin decreases
methamphetamine seeking in male and female rats. Frontiers in Neuroscience,
Seabrock, SC (poster)
Hughes, B.A. & Woodward, J.J. (2011). Dephosphorylation of C-terminal tyrosine
residues does not contribute to ethanol inhibition of recombinant NMDA receptors.
Poster session presented at the Perry V. Halushka Student Research Day, Charleston,
SC.
Smith AW, Wiggins AT, Kalivas PW (2012) Differential roles of matrix
metalloproteinases-2 and -9 in reinstatement of cocaine seeking. Frontiers in
Neuroscience, Seabrook, SC (poster).
Smith AW, Wiggins AT, Kalivas PW ( 2011) Role of matrix metalloproteinases in
reinstatement of cocaine seeking. Society for Neuroscience Annual Meeting. San
Diego, CA (poster)
Smith AW, Wiggins AT, Kalivas PW (2011) Inhibition of matrix Metalloproteinases
attenuates reinstatement of cocaine seeking. Student Research Day, MUSC.
Charleston, SC (poster)
New NN, Mulholland PJ, Chandler LJ (2011) . Epigenetics in the prefrontal cortex
following binge-like adolescence alcohol exposure. Research Society on Alcoholism
Atlanta, GA (poster)
New NN, Glen GW, Gass JT, Mulholland PJ, Chandler LJ. (2011) Adolescent
intermittent ethanol exposure alters dendritic spine morphology in the adult mPFC.
Society for Neuroscience, Washington, DC (poster).
Straight NM, New NN, Gass JT, Mulholland PJ, Chandler LJ (2011) Homer2 deletion
prevents chronic ethanol-induced spine enlargement in the nucleus accumbens .
Society for Neuroscience, Washington, DC (poster).
178
Bentzley, B., Fender, K., & Aston-Jones, G. (2012). Behavioral economics for the
neuroscientist: Demand curve analysis of the within-session threshold procedure.13th
Annual Frontiers in Neuroscience Research Day, Seabrook Island, SC (poster)
Bentzley, B. & Aston-Jones, G. (2012). Microinjection of muscimol into the subthalamic
nucleus attenuates cocaine consumption at high price. Medical Scientist Training
Program Research Day, Charleston, SC.(poster)
Bentzley, B. & See, R.E. (2010). Orexin-1 receptor antagonism blocks acquisition of
cocaine self-administration. Medical Scientist Training Program Research Day, Folly
Beach, SC.(poster)
Ricci R, Salatino A, Li X, Taylor JJ, Bohning D, George MS. (2011) Neural Correlates
of TMS induced neglect in healthy participants: a concurrent TMS/fMRI study.
Fourteenth European Congress on Clinical Neurophysiology and 4th International
Conference on Transcranial Magnetic and Direct Current Stimulation (poster)
Taylor JJ, Borckard JJ, George MS. (2012) Endogenous opioids mediate left
dorsolateral prefrontal cortex rTMS-induced analgesia. 23rd Annual Meeting of the
American Neuropsychiatric Association. (poster)
Salatino A, Li X, Taylor JJ, Mu Q, Bohning D, George MS, Ricc (2012) Imaging the
neural correlates of rightward neglect-like bias in healthy volunteers: an interleaved
TMS/fMRI study. 8th Federation of European Neuroscience Societies (FENS) Forum of
Neuroscience . (poster)
Hanlon CA, Canterberry M, Taylor JJ, DeVries W, Li X, Brown TS, George MS (2012).
Differentiating neural networks with interleaved TMS-BOLD imaging. Society for Brain
Mapping and Therapeutics. Annual Meeting, Toronto, CA. (poster)
Hanlon CA, Canterberry M, Taylor JJ, DeVries W, George MS.(2012) Differentiating
neural networks with interleaved TMS-BOLD imaging: insight into addiction. Society for
Neuroscience New Orleans, LA (poster)
Keren, N.I., Vazey, E.M., Taheri, S., Eckert, M.A., Aston-Jones, G. (2012). Tonic and
phasic optogenetic stimulation of the rat locus coeruleus during fMRI implicates distinct
cortical and subcortical BOLD activation patterns. Society for Neuroscience, NewOrleans, LO (poster).
Keren, N.I., Vazey, E.M., Taheri, S., Eckert, M.A., Aston-Jones, G. (2012). Tonic and
phasic optogenetic stimulation of the rat locus coeruleus during fMRI implicates distinct
cortical and subcortical BOLD activation patterns 7th Brain Research Conference on
Optogenetics and Pharmacogenetics in Neuronal Function and Dysfunction, New
Orleans, LO (poster).
179
Vazey, E.M., Cope, Z.A., Keren, N.I., Moorman, D.E., Eckert, M.A., Aston-Jones, G.
(2012,). Roles of locus coeruleus noradrenergic neurons in cortical network activity and
behavioural functions: Optogenetic and pharmacogenetic studies. 7th Brain Research
Conference on Optogenetics and Pharmacogenetics in Neuronal Function and
Dysfunction, New Orleans, LO (poster).
Keren, N.I., Gregory, N.C., Taheri, S., Vazey, E.M., Vaden, K.I., Morgan, P.S., Welsh,
C.A., Granholm, A.C., Aston-Jones, G., Eckert, M.A. (2012). The human locus
coeruleus in neurodegenerative disease: Post-mortem histology and magnetic
resonance microscopy at 7T. 13th annual Frontiers in Neuroscience Research Day,
Seabrock, SC (poster).
Keren, N.I., Gregory, N.C., Vaden, K.I., Vazey, E.M., Morgan, P.S., Hinson, V.A.,
Taheri, S., Granholm, A.C., Aston-Jones, G., Eckert, M.A. (2011). The human locus
coeruleus in healthy individuals and neurodegenerative disease: Post-mortem magnetic
resonance imaging and histology. Society for Neuroscience, Washington, DC (poster).
Keren, N.I., Morgan, P.S., Gregory, N.C., Granholm, A.C., Hinson, V.A., Aston-Jones,
G., & Eckert, M.A. (2011). Ex-vivo investigation of the human locus coeruleus. 17th
Annual Meeting of the Organization on Human Brain Mapping, Quebec City, Canada
(poster).
Cope, Z.A., Vazey, E.M., Moorman, D.E., Keren, N.I., Lavin, A., Hinson, V.K., Eckert,
M.A., Floresco, S.B., Granholm, A.C., & Aston-Jones, G. (2011). Optogenetic
stimulation of locus Coeruleus norepinephrine neurons in rats performing set-shifting
tasks: modulation of cognitive flexibility. 11th International Neural Transplantation and
Repair conference, Clearwater Beach, FL (poster).
Vazey, E.M., Cope, Z.A., Keren, N.I., Lavin, A., Hinson, V.K., Eckert, M.A., Granholm
A.C., & Aston-Jones, G. (2011). Novel methods for modulating locus coeruleus
noradrenergic function in-vivo. 11th International Neural Transplantation and Repair
conference, Clearwater Beach, FL (poster).
Kuchinsky, S.E., Vaden, K., Keren, N.I., Harris, K.C., Ahlstrom, J.B., Dubno, J.R., &
Eckert, M.A. (2010). Word intelligibility and age predict visual cortex activity during
word listening. Society for Neuroscience, San-Diego, CA (poster).
Vaden, K., Keren, N.I., Harris, K.C., Ahlstrom, J.B., Dubno, J.R., & Eckert,
M.A. (2010). Sublexical processing in left inferior frontal gyrus depends on word
intelligibility. the Society for Neuroscience, San-Diego, CA (poster).
Eckert, M.A., Kuchinsky, S., Keren, N.I., Conner, C., Vaden, K., Ahlstrom, J., &
Dubno, J. (2010, June). Sustained inferior frontal activation predicts age-related
changes in word recognition. 16th annual meeting of the Organization for Human Brain
Mapping, Barcelona, Spain (poster).
180
B. Go, Boger HA, McGinty JF. (2009) Oxidative stress mrna changes in the substantia
nigra of 3 month old methamphetamine-treated gdnf heterozygous versus wildtype
mice.
Society
for
Neuroscience,
Chicago,
IL
(poster)
B. Go, Boger HA, McGinty JF MPTP (2010) neurotoxicity in nigrostriatal dopamine
neurons is exacerbated in gdnf heterozygous mice. Society for Neuroscience, San
Diego,
CA,
(poster)
B. Go, McGinty JF. (2012) Contribution of BDNF/TrkB signaling in rat striatum in
response to acute amphetamine administration. 13th Annual Frontiers in Neuroscience
Research Day, Seabrook Island, SC, (poster)
B. Go, McGinty, JF. (2012) TrkB agonist, 7,8-Dihydroxyflavone-induced GluN2containing NMDA receptor expression in the prefrontal cortex of rats. Society for
Neuroscience, New Orleans, LA,
Parsegian A, Lavin A, See RE. (2008) Cognitive performance and prefrontal activity
following chronic methamphetamine self-administration. Society for Neuroscience 455.1
Parsegian A, Lavin A, See RE. (2009) Chronic methamphetamine self-administration
alters neuronal activity in prelimbic cortex of rats showing selective impairment in the
Attention Set Shift Task. Society for Neuroscience 650.14
Parsegian A, Lavin A, See RE (2010) Extracellular glutamate release in the dorsal
medial prefrontal cortex during reinstatement of methamphetamine-seeking rats.
Translational Research in Methamphetamine Addiction conference.
Parsegian A, Novak A., See RE (2011) Changes in extracellular glutamate and
monoamines in the dorsomedial prefrontal cortex during reinstatement of
methamphetamine-seeking in rats. Society for Neuroscience 689.18
Parsegian A, Novak A., See RE (2011) Altered Extracellular Glutamate and
Catecholamines in the dorsomedial prefrontal cortex during reinstatement of
methamphetamine-seeking in rats. Catecholamines Gordon Research Conference
Kozel FA, Johnson KA, Laken SJ, Grenesko EL, Smith JA, et al. (2009) Can
simultaneously acquired electrodermal activity improve accuracy of fMRI detection of
deception? Soc Neurosci.;4(6):510-17. Chicago Il.
Smith JA, Das A, Wallace GC IV, Ray SK, Banik NL.(2012) Estrogen receptor agonists
protect against glutamate excitotoxicity in rat spinal cord slices. American Society for
Neurochemistry Meeting, Baltimore, MD.
181
Smith JA, Das A, Gibson C, Varma AK, Ray SK, and Banik NL.(2011) Estrogen
Receptor Agonists Attenuate TNF-α-Induced Cell Damage and Apoptosis in VSC4.1
Motoneurons. American Society for Neurochemistry Meeting, St. Louis, MO.
Smith JA, Das A, Butler JT, Ray SK, and Banik NL.(2009) Estrogen or Estrogen
Receptor Agonist Inhibits Lipopolysaccharide Induced Microglial Activation and Death.
American Society for Neurochemistry Meeting, Charleston, SC
Spencer K and Chandler JL (2012) Chronic ethanol exposure decreases Kv4.2 channel
and KChIP3 expression in the hippocampus. Research Society on Alcoholism Annual
Meeting
Stefanik, M.T., Kupchik, Y.M., Moussawi, K. , Deisseroth, K., LaLumiere, R.T., Kalivas,
Inhibition of Relapse Neurocircuitry. Optogenetics and
P.W (2012) . Optogenetic
Pharmacogenetics in Neural Function and Dysfunction. New Orleans, LA: 7th Brain
Research Conference
Stefanik, M.T., Kalivas, P.W. (2012) Optical inhibition of nucleus accumbens
projections differentially contribute to the relapse to cocaine seeking. . New Orleans,
LA. Molecular and Cellular Cognition Society Annual Meeting.
Stefanik, M.T., Kalivas, P.W. (2012) Optical inhibition of nucleus accumbens
projections differentially
contribute to the relapse to cocaine seeking. SFN. New
Orleans, LA: Society for Neuroscience
Stefanik, M.T., Kalivas, P.W. (2012) Optogenetic interrogation of relapse neurocircuitry.
Seabrock, SC Medical University of South Carolina Frontiers in Neuroscience Research
Da.,
Stefanik, M.T., Deisseroth, K., Kalivas, P.W. (2011) Lights on, relapse off: Examining
optogenetic inhibition of
relapse neurocircuitry. Washington, DC: Society for
Neuroscience
Stefanik, M.T., Kupchik, Y., Deisseroth, K., Kalivas, P.W.(2011) Lights on, relapse off:
Examining optogenetic inhibition of relapse neurocircuitry. Washington, DC: Molecular
and Cellular Cognition Society .
Stefanik, M.T., Kupchik, Y., Deisseroth, K., Kalivas, P.W. (2011) Lights on, relapse off:
Examining optogenetic inhibition of relapse neurocircuitry. Charleston, SC: Medical
University of South Carolina Student Research Day.
Stefanik, M.T., Kupchik, Y., Deisseroth, K., Kalivas, P.W. (2011) Lights on, relapse off:
Examining optogenetic inhibition of relapse neurocircuitry. Charleston, SC: Medical
University of South Carolina Neuropalooza .
182
Patel, D.D., Stefanik, M.T., Kalivas, P.W.(2011)
Optogenetics and relapse
neurocircuitry: Using halorhodopsin
to alter nucleus accumbens function in drug
seeking. Charleston, SC: College of Charleston Honors College Student Research
Day.
Stefanik, M.T. and Kalivas, P.W. (2011) Optical silencing of the nucleus accumbens
core attenuates drugseeking behavior. Charleston, SC: Medical University of South
Carolina Frontiers in Neuroscience Research Day,
Stefanik, M.T., Moussawi, K., Deisseroth, K., Kalivas, P.W., LaLumiere, R.T.(2010)
Shining the light on relapse
neurocircuitry: Modulating the reinstatement of drugseeking behavior using an optogenetic
approach.. San Diego, CA: Society for
Neuroscience.
Stefanik, M.T., Moussawi, K., Deisseroth, K., Kalivas, P.W., LaLumiere, R.T.(2010)
Shining the light on relapse neurocircuitry: Modulating the reinstatement of drugseeking behavior using an optogenetic
approach. Charleston, SC: Medical University
of South Carolina Student Research Day.
Swearing J and Joseph J (2012) Brain Networks in Autism Spectrum Disorder: a graph
theoretic approach to functional connectivity SFN, New Orleans
McGlinchey E, Mahler SV,Vazey EM, Roth BL, and Aston-Jones G (2012) . DREADDMediated Inhibition of Rostral vs. Caudal Ventral Pallidum Neurons in Cue-Induced
Reinstatement of Cocaine Seeking in Rats. Frontiers in Neuroscience, Seabrook, SC
McGlinchey E, Mahler SV, Aston-Jones G (2012). Medial prefrontal cortex afferents to
the nucleus accumbens core, but not to the ventral tegmental area, are activated during
cue-induced reinstatement of cocaine seeking. Society for Neuroscience, New Orleans
Oral Presentations:
Beckley JT, (2011). Acute toluene exposure induces persistent alterations in synaptic
transmission in key regions of the addiction neurocircuitry. International Drug Abuse
Research Society. Istanbul, Turkey
Keren (2012) “See me now? Investigating LC structural and functional biomarkers
with high-field MR microscopy and ofMRI”. Cognitive Neuroscience Center, Department
of Neurosciences, Medical University of South Carolina (oral presentation).
Keren (2012)
“Preclinical neuroimaging investigation of the locus coeruleus in the
rat, and establishing an MRI biomarker”. Preclinical Imaging Group, Center for
Biomedical Imaging, Medical University of South Carolina. (oral presentation)
183
Keren (2011)
“Overview of LC Imaging Studies”. Inaugural Medical University of
South Carolina – University of South Carolina Imaging Retreat. Center for Biomedical
Imaging, Medical University of South Carolina. (oral presentation)
Spencer, K and Chandler, JL (2012) Chronic ethanol-induced plasticity involves
bidirectional modulation of NMDA receptors and Kv4.2 channels by KChIP3- talk
Society for Neuroscience, New Orleans
Taylor JJ. (2012) Endogenous Opioids Mediate Left Dorsolateral Prefrontal Cortex
rTMS-Induced Analgesia. 23rd Annual Meeting of the American Neuropsychiatric
Association (oral presentation)
STUDENTS HONORS/AWARDS
Barrett
2011-2012 GAANN Fellowship MUSC
Barry:
Beckley:
2011-2013 NIH - NIDA F31 Individual National Research
“Neuroplasticity Associated with Acute Toluene Inhalation”
Service
Award:
2013 Howard Hughes Medical Institute Teacher Training Fellowship, College of
Charleston
Buchta:
Cox
2012 NIDA Women & Sex/Gender Junior Investigator Travel Award for the meeting of
the College on Problems of Drug Dependence (CPDD)
2011 T32 – NIDA Institutional National Research Service Award
2011 Sigma Xi award- best poster presentation MUSC student research day
Smith
2012 NIDA Early Career Investigator Travel Award for APA Conference
New
2012 Ruth L. Kirschstein National Research Service Awards for Individual Predoctoral
Fellows (F31)Title: Adolescent Alcohol, Epigenetics, and Alterations in the Adult
Prefrontal Cortex
184
Cope
2010-2011 GSA Vice President
2011-2012 GSA President
2011 Provost's Scholar Graduate Studies Fall
Bentzley
2012 American Society for Clinical Pathology Award for Academic Excellence and
Achievement, Medical University of South Carolina Presented to the second year
medical student who best fulfills the ASCP award criteria – general academic
excellence and promise.
2010-2012 Medical Scientist Training Program Grant Support, Medical University of
South Carolina I was chosen to be included as a trainee on MUSC’s MSTP grant (T32)
for the past two years.
2010 McGraw Hill Lange Medical Student Award Medical University of South Carolina
This award is given to a medical student who has demonstrated excellence in their
academic achievements by being at the top of their class at the end of their first year of
training.
2009 UMA/MSTP Scholar Medical University of South Carolina This scholarship
covered my academic expenses and stipend during my first year at MUSC. It is award
by the University Medical Associates to an incoming MD/PhD student who displays
particularly high potential for a career as a physician scientist.
Taylor
2012 College of Graduate Studies Most Outstanding Student Volunteer, MUSC
2012 Selected for NINDS/AUPN
Neuroscience Symposium
Combining
Clinical/Research
Careers
in
2012 1st Place Poster Presentation, 13th Annual Frontiers in Neuroscience Research
Day, MUSC
2012 NIDA NRSA F30 Fellowship Award, National Institutes of Health
2012 Penn Fellowship in Neuroscience & Society, University of Pennsylvania
2012 American Neuropsychiatric Association (ANPA) Young Investigator Award
2011 Student Research Honorable Mention, Ralph H. Johnson VAMC
2011 Women’s Club Scholarship, Medical University of South Carolina
185
2011 Howard Hughes Medical Institute Teacher Training Fellowship, College of
Charleston
Keren
2012 Neuroscience Institute International Trainee Award (pre-doctoral
Fellowship), Department of Neurosciences, Medical University of South Carolina
2011 Neuropalooza Poster Award, Medical University of South Carolina and College of
Charleston.
Stefanick:
2012 NIDA Predoctoral Institutional National Research Service Award: Drug Abuse
Training Program (T32 DA7288), PI: Jacqueline McGinty, Ph.D
2009-2010 G.A.A.N.N (Graduate Assistantship in an Area of National Need) Fellowship
in Teaching and Instruction Medical University of South Carolina – Charleston, SC
2009 MUSC Coconut Cake Scholarship Recruitment Award Medical University of South
Carolina – Charleston, SC
Parsegian
2009-2011 T32 – NIDA Institutional National Research Service Award
2011
Student Representative of the Society for Neuroscience South Carolina Chapter
2011- 2012 Ruth L. Kirschstein National Research Service Award, NIDA
2011 NIDA/NIAAA/APA Early Career Investigators Travel Award,
2011
MUSC Student Research Day, 1st place winner, PhD Oral Presentation
category
2012
MUSC Graduate Studies Travel Award, December 2012
Anticipated Graduations
Beckley - December 2013
Go - Summer 2013
Parsegian - December 2012
Swearingen - 2013
Taylor - Fall 2012 (graduate school)/Spring 2015 (medical school)
186
Accomplishments 2011-2012
•
•
•
•
•
Five incoming PhD students chose to enter the NS training program
Two MD/PhD students chose to enter the NS training program
Five students successfully completed their written qualifying exams
Five students completed their dissertation proposal
Created new electives
Goals for 2012-2013
•
•
•
•
Increase faculty involvement in teaching and mentoring
Restructure the administrative structure of the NS graduate program
Continue to encourage students to apply for NRSA awards
Initiate formal annual review procedures to access progress of each graduate
student
187
Nursing PhD Program
Gail Gilden, RN, ScD, Director
Students
Student
Allen, Diane
Anderson, Tonya
Aselage, Melissa (Graduate)
Atassi, Katherine (Graduate)
Atz, Teresa
Auxier, Nicole
Bentley, Angela
Year
Started
2008
2010
2008
2007
2010
2010
2010
Budak, Amanda (Candidate)
Campanella, Hollie (Candidate)
Caraviello, Kelly (Withdrew)
Carnevale, Teresa (Candidate)
Craven, Heather
Crook, Edith
2007
2008
2010
2008
2007
2011
DeGuzman, April (Candidate)
Ferdinandi, Melissa T (Candidate)
Fink, Lilo
Flavin, Susan
Freeman, Rebecca (Candidate)
French, Kim (Candidate)
Fruda, Charlene (LOA)
Gaynor, Jessica (LOA)
Gilbert, Sarah
Goers, Jama
Grahn, Elizabeth
Hudson, Shannon Marie
(Candidate)
Kennedy R.N., Margaret B
(Candidate)
Lawson, Theresa G. (Graduate)
Lutz, Fairuz
2005
2009
2010
2011
2008
2007
2011
2011
2008
2010
2010
2009
Loftin, Collette (Graduate)
Mathieu, Kristen (Withdrew)
Matutina, Robin (Graduate)
McCulloh Nair, Julie
2008
2011
2007
2011
Mentor
Dr. Charlene Pope
Dr. Carolyn Jenkins
Dr. Elaine Amella
Dr. Barbara Edlund
Dr. Teresa Kelechi
Dr. Marilyn Laken
Dr. Jeannette
Andrews
Dr. Lynne Nemeth
Dr. Gail Gilden
Dr. Gail Stuart
Dr. Gail Stuart
Dr. Gail Gilden
Dr. Gayenell
Magwood
Dr. Teresa Kelechi
Dr. Charlene Pope
Dr. Lynne Nemeth
Dr. Ida Spruill
Dr. Marilyn Laken
Dr. Charlene Pope
Dr. Berry Anderson
Degree
Sought
PhD
PhD
PhD
PhD
PhD
PhD
PhD
PhD
PhD
PhD
PhD
PhD
PhD
Dr. Barb Edlund
Dr. Teresa Kelechi
Dr. Teresa Kelechi
Dr. Marilyn Laken
PhD
PhD
PhD
PhD
PhD
PhD
PhD
PhD
PhD
PhD
PhD
PhD
2009
Dr. Gail Gilden
PhD
2006
2011
Dr. Teresa Kelechi
Dr. Jeannette
Andrews
Dr. Susan Newman
Dr. Gail Gilden
Dr. Teresa Kelechi
Dr. Marilyn Laken
PhD
PhD
188
PhD
PhD
PhD
PhD
Mikhail, Judy N (Candidate)
Mollica, Michelle
Monfre, Jill M. (Graduate)
Naccarato, Mary
O’Brien, Tara
Painter, Amy (Withdrew)
Paguntalan, John
Pellitier, James (Candidate)
Pendergrass, Michelle (Candidate)
Primrose, Janet W. (Graduate)
Raynor, Phyllis
Sell, Kimberly (Candidate)
Smith, Georgette M (Candidate)
2009
2011
2009
2008
2010
2010
2011
2005
2007
2006
2011
2009
2009
Smith, Julia Watkins (Candidate)
Smith, Lenora
Smith, Lynette (Graduate)
Spriggle, Melinda (Withdrew)
2004
2010
2009
2011
Sutton, Suzanne
Szajna, Amy
Thul, Genevieve (Graduate)
VanRavenstein, Kathryn A.
2010
2011
2007
2009
Vick, Lori
Walker, Rebecca
White, Kathy Giarla (LOA)
Winburn, Erin Blythe (Candidate)
Wyatt, Theresa
2010
2010
2011
2009
2011
Dr. Charlene Pope
Dr. Barb Edlund
Dr. Teresa Kelechi
Dr. Teresa Kelechi
Dr. Carolyn Jenkins
Dr. Gail Stuart
Dr. Berry Anderson
Dr. Charlene Pope
Dr. Carolyn Jenkins
Dr. Carolyn Jenkins
Dr. Charlene Pope
Dr. Elaine Amella
Dr. Jeannette
Andrews
Dr. Gail Stuart
Dr. Elaine Amella
Dr. Gail Stuart
Dr. Jeannette
Andrews
Dr. Gail Gilden
Dr. Susan Neman
Dr. Gail Gilden
Dr. Jeannette
Andrews
Dr. Gail Stuart
Dr. Lynne Nemeth
Dr. Sheila Smith
Dr. Charlene Pope
Dr. Gail Gilden
PhD
PhD
PhD
PhD
PhD
PhD
PhD
PhD
PhD
PhD
PhD
PhD
PhD
PhD
PhD
PhD
PhD
PhD
PhD
PhD
PhD
PhD
PhD
PhD
PhD
STUDENT PUBLICATIONS
Journals:
Budak, A.R. (March, 2012) A Framework of Food Cravings and Weight Loss after
Bariatric Surgery: Application of the Cognitive Processing Model. Bariatric Nursing and
Surgical Patient Care. 7(1): 25-29. doi:10.1089/bar.2012.9994.
Loftin, C., Newman, S.D., Dumas, B.P, Gilden, G., and Bond, M.L. (2012). Perceived
Barriers to Success for Minority Nursing Students: An Integrative Review. ISRN (in
press).
189
Loza, M.J., Brodmerkel, C., duBois, R.M., Judson, M.A., Costabel, U., Drent, M.,
Kavuru, M., Flavin, S., Lo, K.H., Barnathan, E.S., Baughman, R.P. Inflammatory profile
and response to anti-TNF therapy in patients with chronic pulmonary
sarcoidosis. Clinical and Vaccine Immunology 2011 Jun;18(6):931-9.
Matutina, R. (2012). The still, quiet voice. Journal of Christian Nursing, 29(2), 121.
Matutina, R., Hamner, S., Battaglia, R. (2012). Redefining and categorizing the
perceived value of the RN in ambulatory care, AAACN Viewpoint, 34(1), 1, 8-10.
Matutina, R., Mueller, M., & Kelechi, T. (2011). Racial differences in pain reports
between Black and White participants with chronic venous disorders treated with
cryotherapy compared to usual care. Ethnicity & Disease, 21, 451-457.
Newburger, J.W., Sleeper, L.A., Bellinger, D.C., Goldberg, C.S., Tabbutt, S., lu,
M.,Mussatto, K.A., Williams, I.A., Gustafson, K.E., Mital, S., Pike, N., Sood, E., Mahle,
W.T., Cooper, D.S., Dunbar-Masterson, C., Krawszeski, C.D., Lewis, A., Menon, S.D.,
Pemberton, V.L., Ravishankar, C., Atz, T.W., Ohye, R.G., Gaynor, J.W. (2012). Early
developmental outcome in children with hypoplastic left heart syndrome and related
anomalies. Circulation, 125, 2081-2091.
Ravishankar, C., Zak, V., Bellinger, D., Cook, A., Gyanor, J.W., Ghanayem, N.,
Krawezeski, C., Licht, D.J., Mahoney, L., Newburger, J., Pemberton, V., Atz., T.,
Khainkin, S., Sananes, R., Williams, I.A., Williams, R.V., Hsu, D. (2011). Linear growth
failure is associated with worse neurodevelopmental outcome in infants with single
ventricle physiology. Journal of American College of Cardiology, 57 (14), E420
Richards, T. J., Kaminski, N., Baribaud, F., Flavin, S., Brodmerkel, C., Horowitz, D.,
Gibson, K. F. (2012). Peripheral Blood Proteins Predict Mortality in Idiopathic
Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine
185(1), 67-76.
Smith G & Wagner JL. (2012). Commentary on “Care delivery and self-management
strategies for children with epilepsy.” Evidence-Based Child Health: A Cochrane Review
Journal, DOI: 10.1002/ebch.1818.
Thul, G.M. (2012). Reliability of Vital Sign Measurement in Nursing Students (doctoral
dissertation). Medical University of South Carolina, Charleston, SC.
Virzi, L, Atz, T, Barnard, T, Dunbar-Masterson, C, Ghanayem, G, Jacobs, J, Lambert, L,
Lewis, A, Pearson, G, Pemberton, V, Pike, N, Pizarro, C, Radojewski, E, Tabbutt, S,
Teitel, D, Xu, M, Ohye, R. Reporting Adverse Events in a Surgical Trial for Complex
Congenital Heart Disease: The Pediatric Heart Network Experience. Journal of Thoracic
and Carciovascular Surgery, 142(3), 531-537.
190
Wagner JL, Smith, G & Ferguson, PL. (accepted 02/12). The relationship of coping
behaviors to depressive symptoms in youth with epilepsy: An examination of caregiver
and youth proxy report. Epilepsy & Behavior.
Wagner JL, Smith, G & Ferguson, PL. (accepted 02/12). Self-efficacy for seizure
management and youth depressive symptoms: Caregiver and youth perspectives.
Seizure: European Journal of Epilepsy.
Wagner, J.L., Smith, G., Ferguson, P., van Bakergem, K., and Hrisko, S. (2011).
Feasbility of a pediatric cognitive-behavioral self-management intervention: Coping
Openly
and
Personally
with
Epilepsy
(COPE).
Seizure,
doi:
10.1016/j.seizure.2011.02.010.
Book Chapters
Ferguson, PL, Wannamaker, BW, Smith, G, Wagner, JL, and Selassie, AW. (2012).
Epidemiology, Impact, and Comorbid Conditions, chapter in Handbook of Epilepsy:
Diagnosis and Management (2nd Ed.), MUSC University Press.
Smith, G, Edwards, JC, Ferguson, PL, Wagner, JL, and Wannamaker, BW. (2012).
Moving Forward with Comprehensive Epilepsy Care, chapter in Handbook of Epilepsy:
Diagnosis and Management (2nd Ed.), MUSC University Press.
Thul, G.M. (2012). Contributor. Lippincott’s Nursing Procedures and Skills (4th ed.).
Philadelphia: Lippincott, Williams & Wilkins.
Presentations
Campanella, H.
June 15, 2012 Knowledge is power: Preventing Elder
Abuse. (Featured Presenter: 60 minute oral presentation) at Certified Nurse Assistant
(CNA) Leadership Conference. Colorado Health Care Association. Summit Event
Center, Denver, Colorado.
Campanella, H. January 2012 & August 2012 Understanding Elder Abuse. Featured
presenter at the Long Term Care Leadership Development Workshops. Colorado
Center for Nursing Excellence, Multiple locations, Colorado.
Campanella, H. January 2012. Building Public Will to Achieve Access to Health
Project. 100 Nurse Community Speakers. Colorado Center for Nursing Excellence in
collaboration with the Colorado Trust. Multiple locations, Colorado.
Campanella, H. 2012. Elder Abuse (EA) Screening by RNs in Primary Care:
Prevalence & Exploration of Adverse Effects poster presented at Medical University of
South Carolina (MUSC) College of Nursing (CON) Annual Student Research Day.
191
Guifoyle, S., Wagner, J., Smith, G., and Modi, A. (2011). Early screening and
identification of psychological co-morbidities in children with epilepsy is necessary.
Poster presented to December 2011, 5th North American Regional Epilepsy Congress,
Baltimore, MD.
Matutina, R., Hamner, S., Battaglia, R. (2012, June). Redefining and Categorizing the
Perceived Value of the RN in Ambulatory Care. Poster session presented at the 5th
Nursing Economic$ Summit, Washington, DC.
Matutina, R., Hamner, S., Battaglia, R. (2012, May). Redefining and Categorizing the
Perceived Value of the RN in Ambulatory Care. Poster session presented at the MUSC
Nurses Week Poster Fair, Charleston, South Carolina.
Matutina, R., Kelechi, T., & Mueller, M., Jenkins, C., Johnson, J. (2012,
May). Educational interventions for middle school students to improve the perception of
nursing as a future career choice. Poster session presented at the MUSC Nurses Week
Poster Fair, Charleston, South Carolina.
Matutina, R., Hamner, S., Battaglia, R. (2012, April). Redefining and Categorizing the
Perceived Value of the RN in Ambulatory Care. Poster session presented at the 2012
Roper St. Francis Healthcare Nursing Research Conference, Charleston, South
Carolina.
April). Educational interventions for middle school students to improve the perception of
nursing as a future career choice. Poster session presented at the 2012 Roper St.
Francis Healthcare Nursing Research Conference, Charleston, South Carolina.
February). Educational interventions for middle school students to improve the
perception of nursing as a future career choice. Poster session presented at the 26th
annual Southern Nursing Research Society conference, New Orleans, Louisiana.
Matutina, R., Kelechi, T., & Mueller, M. (2011, November). Middle school student’s
perception of nursing as a career. Poster session presented at the Perry V Halushka
Medical University of South Carolina Student Research Day, Charleston, South
Carolina.
Matutina, R., Kelechi, T., & Mueller, M. (2011, September). Middle school student’s
perception of nursing as a career. Poster session presented at the 1st Medical
University of South Carolina College of Nursing Student Research Day 2011,
Charleston, South Carolina. Awarded 1st place.
Mollica, M. Online peer mentoring program for nursing students: An integrative review
and project proposal. Poster session presented at the New York State Nurses
Association, District 1 Research Day.
192
Monfre, Jill. (2012,June). Assessing the impact of chronic wound pain on health
related quality of life. Poster session presented at the Wound Ostomy Continence
Nurses Society, Charlotte, North Carolina.
O’Brien, Tara. (February, 2012). Family Influence, Stress, and Health Behaviors
among older Appalachian women. Poster session presented at Southern Nursing
Research Society in New Orleans, LA.
Invited: Smith, G. Identifying and Addressing the Comorbidities of Epilepsy. MUSC
Epilepsy Boot Camp for Professionals in Charleston, SC. April, 20, 2012.
Invited: Smith, G. Coping with epilepsy: Family & self-management. Presented with
Janelle Wagner, PhD. Managing Well Epilepsy Network via teleconference on April 5,
2012.
Invited: Smith, G. New Evidence in Psychosocial Interventions for Managing Epilepsy:
Introduction and Conclusion. American Epilepsy Society’s 65th Annual Conference:
Professionals in Epilepsy Symposium in Baltimore, MD. December 4, 2011.
Smith, L. (2012). Nutrition decisions in the dying. Poster presentation at Southern
Nursing Research Society Annual Conference, New Orleans, LA.
Funded Research
Macias, M. and Smith, G.
August 2011-August 2015
Maternal Child Health
Role: Co-Principal Investigators
Project Title: South Carolina Leadership Education in Neurodevelopmental and Related
Disabilities
Goal(s): South Carolina Leadership Education in Neurodevelopmental and Related
Disabilities (SC LEND) is a state-wide interdisciplinary training program established to
improve the health of infants, children, and adolescents with autism spectrum
disorders(ASD) and neurodevelopmental disorders (ND). SC LEND trainees are
prepared as leaders in their field in the interdisciplinary care of and advocacy for
individuals with ASDs and NDs. The SC LEND training program is housed at three
sites: the Medical University of South Carolina, Greenville Hospital System University
Medical Center, and the University of South Carolina School of Medicine. Each trainee
will have a home site but have the opportunity to participate in training activities with all
trainees across the three sites.
Principal Investigator: Selassie, A.
October 2011-October 2015
Award Amount: $3 million
Project Title: Health Outcomes in Persons with Epilepsy in South Carolina
193
Role: Gigi Smith, Co-Investigator, 20%
Goal(s): Epidemiologic Research in Epilepsy to obtain new knowledge of the prevalence
and/or incidence of epilepsy among various U.S. populations or subpopulations; risk
factors or other determinants that affect epilepsy incidence or outcomes; healthcare
needs in epilepsy populations; and/or early predictors of healthcare needs among
incident cases of epilepsy.
STUDENT HONORS
Melissa B. Aselage, Melissa (PhD 2011)
2012-2014 John A. Hartford Foundation Claire M. Fagin Fellow
Atz, Teresa
Blue Cross Blue Shield Nurse Scholar Award
Kehinde, Julius (PhD 2011)
National Institute on Aging, Summer Institute on Aging Research
Matutina, Robin
Medical University of South Carolina College of Nursing Student Research Day Poster
Presentation (1st place)
Mollica, Michelle
Faculty of the Year Award for D'Youville College
O’Brien, Tara
Directors Award for Best Teaching Practices
Medical University of South Carolina Research Day poster presentation, 2nd Place
Award
Smith, Gigi
South Carolina Deans and Directors of Nursing Faculty Scholarship
Sigma Theta Tau New Investigator Award for Caregiving in Pediatric Epilepsy
(dissertation research)
Research and Education in Epilepsy Fund Predoctoral Award for Caregiving in Pediatric
Epilepsy (dissertation research)
Vick, Lori
Advisor of the Year awarded by the Black Awareness Organization
National Institute of Nursing Research (NINR) Summer Genetics Institute (SGI) at the
National Institutes of Health, Bethesda, MD June 4-29
194
PROFESSIONAL ORGANIZATIONS
Caldieraro-Bentley, Angela
Sigma Theta Tau, Nu Pi Chapter, Springfield, IL
Midwest Nursing Research Society
Southern Nursing Research Society
American Association of Critical Care Nurses
Preventive Cardiovascular Nurses Association
Society for Vascular Nursing
American Heart Association, Scientific Council - Nursing
American College of Cardiology
American Nurses Credentialing Center Cardiac Vascular Certification Exam Seminar,
peer reviewer
American Nurses Credentialing Center Cardiac Vascular Review Manual, peer reviewer
Campanella, Hollie
American Nurses Association (ANA)
Colorado Nurses Association (CNA)
National League for Nursing (NLN)
National Committee for the Prevention of Elder Abuse (NCPEA), Education Committee
Member
Emergency Nurses Association (ENA)
Sigma Theta Tau – International Honor Society for Nurses
Research Committee. Medical University of South Carolina (MUSC) College of Nursing
(CON)
Reviewer: F.A. Davis and Annals of Internal Medicine
Fink, Lilo
Sigma Theta Tau- Fort Myers Florida
Souther Nurses Research Society
National League of Nurses
American Nurses Pain Association
Flavin, Susan
Sigma Theta Tau
Matutina, Robin
Association of Pediatric Hematology/Oncology Nurses
Sigma Theta Tau, Phi Gamma, member
Sigma Theta Tau, Gamma Omicron, Leadership Succession Committee, member
American Academy of Ambulatory Care Nursing, member
Southern Nursing Research Society, member
195
Mollica, Michelle
Sigma Theta Tau
Oncology Nursing Society
NLN
O’Brien, Tara
Sigma Theta Tau International Honor Society of Nursing, Lambda Omega and Gamma
Iota Chapters
North Carolina Nurses Association
American Nurses Association
Southern Nurses Research Society
Rural Nurses Organization
Gerontological Society of America
Paguntalan, John
Sigma Theta Tau International Honor Society for Nursing
Society of Critical Care Medicine
American Association of Critical Care Nurses
Thul, Genevieve
Simulation sub-committee, Nursing Education Section, Midwestern Nursing Research
Society
Multicultural Task Force Committee, College of Nursing, MUSC
Smith, Gigi
Association of Faculties of Pediatric Nurse Associates and Practitioners
National Association of Pediatric Nurse Practitioners
South Carolina Association of Pediatric Nurse Practitioners
National Organization of Nurse Practitioner Faculties
American Epilepsy Society
Epilepsy Foundation
American Nurses Association (local and national)
American Epilepsy Society Nursing Research Special Interest Group, Co-Chair
American Epilepsy Society, Vice-Chair
Smith, Lenora
Hospice and Palliative Nurses Association, National - Board Development and
Leadership Committee Member
Gerontological Society of America, Abstract Reviewer
Sigma Theta Tau International Honor Society of Nursing, Abstract Reviewer
Gamma Iota Chapter Member
VanRavenstein, Kathy
Southern Nurses Research Society
National League of Nurses
196
CERTIFICATIONS
Caldieraro-Bentley, Angela
American Nurses Credentialing Center Cardiac Vascular Certification
Fink, Lilo
Post Masters Certificate as a Family Nurse Practitioner
Matutina, Robin
Certified Pediatric Nurse (CPN™)
Certified Pediatric Oncology Nurse (CPON®)
Ambulatory Care Nurse Certification (RN-BC)
Mollica, Michelle
OCN certification
O’Brien, Tara
Certified Nurse Educator (CNE)
Paguntalan, John
Adult Nurse Practitioner, Board Certified, American National Credentialing Center
Certified Critical Care Nurse (Alumni)
Meetings:
PhD Committee meetings were held on the dates of. Meeting minutes are
posted in the CON Intranet.
Membership of PhD Committee: Gail Gilden, Carolyn Jenkins, Teresa Kelechi, Susan
Newman (Chair), Ida Spruill, Sally Stroud (Ex-Officio), Jeannette Andrews (Ex-Officio)
and Carolyn Page. Two student representatives joined the committee meetings:
Rebecca Freeman, and Theresa Wyatt.
Students:
As of July 2012, 58 students were actively enrolled in the program.
Progression for the year was as follows:
 4 students withdrew from the PhD Program: Melinda Spriggle (financial reasons),
Amy Painter (personal reasons), and Kelly Caraviello (health reasons). Kristin
Mathieu (financial reasons).
 3 students took a one year LOA, hoping for better financing (Jessica Gaynor,
Charlene Fruda, Kathleen Giarla White)
 9 students successfully defended and graduated: Melissa Aselage, Kathy Atassi,
Teresa Lawson, Collette Loftin, Robin Matutina, Janice Primrose, Genevieve
Thul, Jill Monfre, and Lynette Smith.
 16 students are in candidacy status: Amanda Budak, Hollie Campanella, Teresa
Carnavale, April DeGuzman, Melissa Ferdinandi, Rebecca Freeman , Kim
197
•
French, Margaret Kennedy, Shannon Hudson, Judy Mikhail, Jim Pelletier,
Michelle Pendergrass, Kimbery Sell, Gigi Smith, Julia Smith Watkins and Erin
Blythe Winburn
26 continuing students are enrolled in course work in good academic standing:
Diane Allen, Tonya Anderson, Teresa Atz, Nicole Auxier, Angela Bentley,
Heather Craven, Edith Crook, Lilo Fink, Susan Flavin, Sarah Gilbert, Jama
Goers, Elizabeth Grahn, Fairuz Lutz, Mary Naccarato, Julie Nair McCulloh,
Michelle Mollica, Tara O-Brien, John Paguntalan, Lenora Smith, Suzanne Sutton,
Amy Szajna, Phyllis Raynor, Kathryn Van Ravenstein, Lori Vick, Rebecca
Walker, and Theresa Wyatt.
Matriculated Students for 2012: 18 online students are matriculated for Fall 2012,
maintaining continued growth of program numbers and the new target goal of at least
50 students enrolled in the program.
The incoming students have impressive
credentials and are geographically spread throughout the continental U.S.
Program Strategies:
• 2012 Residency The 7th annual campus residency is scheduled for July 9-12,
2012.
• Quality Improvement Two half-day PhD Faculty Retreats were held in October
2011 and in March 2012 to review the curriculum. Strategies for revision were
formulated with assigned responsibility for implementation and evaluation.
• Website revision PhD program website was redesigned for ease of navigation
and improved appeal to diverse applicants and end users.
• Policy Policies regarding the published manuscript dissertation were refined and
included in the electronic student handbook.
• Evaluation An electronic program satisfaction survey was distributed to students
for tracking satisfaction.
Goals for 2012-2013
1. Maintain the quality of student applicants through marketing of program
outcomes, examination of admission criteria, and scholarship opportunities.
2. Continue to achieve high numbers and rigor of student presentations,
publications, and submitted grants.
3. Integrate interdisciplinary learning experiences into the PhD Program.
4. Implement a PhD Program evaluation plan.
5. Develop faculty advisement abilities to mentor students in an online environment.
6. Promote the standards of excellence in the program of online courses.
198
Victoria Findlay, PhD, Director
Student’s Name
Elizabeth Fowler
Kayla Hill
Claire Hinsch
Lindsay McDonald
Melissa Scheiber
Philip Sobolesky
Tiffany Baker
Joshua Kellner
Dion Foster
Matriculation Date
Fall 2009
Fall 2010
Fall 2007
Fall 2009
Fall 2007
Fall 2009
Fall 2007
Fall 2007
Fall 2011
Mentor
Dr Moussa
Dr Sha
Dr Dammai/Schulte
Dr LaRue
Dr Watson
Dr Moussa
Dr Cunningham
Dr Zhou/LaRue
Dr Turner
Degree Sought
PhD
PhD
PhD
PhD
PhD
PhD
MD/PhD
PhD
MS
Journals
Bannan BA, Van Etten J, Kohler JA, Tsoi Y, Hansen NM, Sigmon S, Fowler E, Buff H,
Williams TS, Ault JG, Glaser RL, Korey CA. The Drosophila protein palmitoylome:
characterizing palmitoyl-thioesterases and DHHC palmitoyl-transferases. Fly (Austin).
2008 Jul-Aug;2(4):198-214. PMID: 18719403 [PubMed - indexed for MEDLINE]
Fowler E, Woolworth J, Quigley DI, Wolff DJ. Assessment and Validation of an
Automated Capture/Analysis System for FISH to Detect Urothelial Carcinoma.
Submitted, under review 2012
Fowler EB, Woolworth JA, Ellerbe C, Sobolesky PM, Shao Y, Keane T, Wolff D,
Watson DK, Moussa O. Analysis of Apoptosis Regulators, including Inhibitors of
Apoptosis and BFAR and Stannin, as Diagnostic Markers for Bladder Cancer.
Submitted, Under Review, 2012.
Chen F-Q, Hill K, Guan Y-J, Schacht J, Sha S-H. Activation of apoptotic pathways in
the absence of cell death in an inner-ear immortomouse cell line. Hearing Research
284:33-41, 2011. doi: 10.1016/j.heares.2011.12.007
Sui M, Jiang D, Hinsch C and Fan W (2009). Fulvestrant (ICI 182,780) Sensitizes
Breast Cancer Cells Expressing Estrogen Receptor alpha to Vinblastine and
Vinorelbine. Breast Cancer Research and Treatment. PMID: 19626437
Scheiber MN, Watson PM, Rumboldt T, Findlay VJ, and Watson DK. Loss of FLI1
Expression Promotes Breast Cancer Progression by Modulating Cellular Growth,
Migration, and Invasion. Submitted. Under Review, 2012.
199
Abstracts
Kayla Hill
Kayla Hill, Fu-Quan Chen, Ya-Jun Guan, Jochen Schacht, Su-Hua Sha. Activation of
apoptotic pathways without cell death in an inner-ear OC-1 cell line. 2011 Pathology
Student Research Day, Sep 2 2011
*Poster also presented at the 2011 Perry V. Halushka MUSC Student Research Day,
Nov 4, 2011
*Poster also presented at the 2012 Association for Research in Otolaryngology
Midwinter Meeting, San Diego, CA February 25-29, 2012
Claire Hinsch
Papanna R, Hinsch CL, Dammai VR, Mann LK, Byrd R, Popek E, Tseng CG. Moise Jr.
KJ. Distribution Of Fibroblast Growth Factor Receptors In Fetal Membranes - Insight
Into The Molecular Basis For The Non-Healing Nature Of Amnion/Chorion. Society for
Gynecological Investigation, 58th annual meeting, Miami, FL 2011
Lindsay McDonald
1st Annual Hollings Cancer Center Invasion and Metastasis Retreat, March 2011, poster
presentation
AACR Conference Orlando, Florida, April 2011, poster presentation
Cancer Genes and Molecular Regulation Retreat, December 2011, poster presentation
11th Annual Hollings Cancer Center Retreat, November 2011, poster presentation
Melissa Scheiber
Scheiber MN, Watson PM, Rumboldt T, Findlay VJ, and Watson DK. Reduced FLI1
Migration, and Invasion. MUSC Hollings Cancer Center Breast Retreat, Charleston,
South Carolina, 2011.
Philip Sobolesky
Philip Sobolesky, Elizabeth Fowler, Yuan Shao, Julie Ann Woolworth, Michael T.
Smith, Mohamed Desouki, Dennis Watson, and Omar Moussa. FOXO3a Transcription
Factor Regulation by Thromboxane Receptor-β Signaling: Novel Mechanism for
Malignant Transformation. 2011 Pathology Student Research Day, Medical University of
South Carolina, Charleston, SC September 2, 2011.
Poster also presented at the 2011 Perry V. Halushka MUSC Student Research Day,
Medical University of South Carolina, Charleston, SC November 4, 2011
200
Presentations
Elizabeth Fowler
AACR – Poster Presentation
Characterization of Current and Novel Biomarkers of Bladder Cancer
Kayla Hill
Noise trauma blocks Akt prosurvival signaling via intracellular energy depletion in outer
hair cells. 2012 Department of Pathology and Laboratory Medicine Seminar Series,
April 2, 2012
* Also presented at the 2012 Hearing Science Research Group Seminar Series, March
7, 2012
Claire Hinsch
Characterization of a Novel Cytoplasmic Vesicle Control Mechanism for FGFR1
Signaling Regulation. Pathology and Laboratory Medicine Seminar Series, Medical
university of South Carolina, 2012
Claire Hinsch. A Novel Function of Bves Revealed by Bimolecular Interaction Studies.
Pathology and Laboratory Medicine Seminar Series, Medical university of South
Carolina, 2011
Claire Hinsch and Vincent Dammai. A Novel Function of Bves Revealed by
Bimolecular Interaction Studies. Student Research Day, Medical University of South
Carolina 2011
Jagadish Kummetha Venkata, Claire Leist Hinsch, Demetri D Spyropoulos, Erika T
Brown, Simon C Watkins, Vincent Dammai. RAT Pathway Synchronizes FGFR1
Signaling By Intracellular Sequestration and Controlled PM Delivery of the Receptor.
Student Research Day, Medical University of South Carolina 2011
Papanna R, Hinsch CL, Mann LK, Dammai VR, Byrd R, Popek E, Tseng SCG, Moise
Jr KJ. Distribution of fibroblast growth factor receptors in fetal membranes- An insight
into the molecular basis for the non-healing nature of amnion/chorion. Society for
Gynecological Investigation 58th Annual Meeting March 16-19; Miami, FL. 2011.
Lindsay McDonald
Pathology and Laboratory Medicine Seminar Series, April 2011, presentation
Pathology and Laboratory Medicine Seminar Series April 2012, presentation
Melissa Scheiber
Scheiber MN, Watson PM, Rumboldt T, Findlay VJ, and Watson DK. Defining the Role
of FLI1 in Breast Cancer. Pathology Research Day. Medical University of South
Carolina, Charleston, South Carolina, 2011.
201
Scheiber MN, Watson PM, Rumboldt T, Findlay VJ, and Watson DK. Defining the Role
of FLI1 in Breast Cancer. MUSC Annual Perry V. Halushka Student Research Day,
Charleston, South Carolina 2011.
Scheiber MN, Watson PM, Rumboldt T, Findlay VJ, and Watson DK. Reduced FLI1
Migration, and Invasion. MUSC Hollings Cancer Center Breast Retreat, Medical
University of South Carolina, Charleston, South Carolina, 2012.
Philip Sobolesky
FOXO3a Transcription Factor Regulation by Thromboxane Receptor-β Signaling: Novel
Mechanism for Malignant Transformation. Department of Pathology and Laboratory
Medicine Seminar Series Presented March 14, 2011, Medical University of South
Also presented for Department of Pathology and Laboratory Medicine Proposal
defense. November 21, 2011, Medical University of South Carolina
Elizabeth Fowler passed written and oral qualifiers
Kayla Hill
- Association for Research in Otolaryngology 2012 Midwinter Meeting Graduate
Student/Postdoctoral Fellow Travel Award
-
First Place Winner of Ph.D. II category Poster Presentation, 2011 Perry V.
Claire Hinsch won Pathology and Laboratory Medicine Seminar Series, First Place.
2011
Lindsay McDonald
- 1st Place Prize for poster presentation at the Veterans Affairs Student Research
Day 2011
- 1st Place Prize (Kinard Award) for poster presentation at Perry Halushka
Research Day 2011
- 1st Place Prize for oral presentation in the Pathology and Laboratory Medicine
Seminar Series April 2012
Melissa Scheiber
- 2nd Place Pathology Seminar Series 2011-2012
Philip Sobolesky received Graduate Student Association 2012 outstanding service
member award
202
Department/Accomplishments for 2011-2012
•
•
•
•
•
•
•
•
•
•
Lindsay McDonald completed/passed written qualifying exam October, 2011
Lindsay McDonald completed/passed oral qualifying exam April, 2012
Philip Sobolesky successfully passed written qualifying exam August 2011 and
proposal defense on November 21, 2011.
Tiffany Baker successfully defended her PhD thesis and graduated 2011
Joshua Kellner successfully defended his PhD thesis and graduated 2012
Elizabeth Fowler successfully defended her PhD thesis and graduated 2012
New faculty members Kala Puligilla and Steve Ethier joined the department
Pathology Research Day was held September 2nd 2011 with Dr Carlo Croce from
Ohio State University giving the keynote address
Dion Foster joined the department in Dr Turner’s lab as a masters student
Dayvia Laws was accepted into the masters program for Fall 2012
• Melissa Scheiber To defend late December 2012/early January 2013
• Claire Hinsch to defend 2013
• Kayla Hill to pass written and oral qualifiers in 2012-2013
• Pathology Research Day and Program Exposure will be held August 24th 2012
with Dr Lee from Harvard University to give the keynote address
203
Post Graduate Positions of 2012 Graduates
Name
Degree
Sought
Program
Al-Ayoubi, Adnan
M.D./Ph.D. Pharmacology
MUSC - General Surgery
Baker, DeAnna
M.D./Ph.D. Microbiology &
Immunology
Duke University - Internal
Medicine
Gault, Christopher
M.D./Ph.D. MCBP
University of Pennsylvania Pathology
Heffernan-Stroud,
Linda
M.D./Ph.D. MCBP
Greenville Memorial - Internal
Medicine/Eastern Virginia
Medical Center – Dermatology
Jenkins, Russell
M.D./Ph.D. Biochemistry &
Molecular Biology
Massachusetts General Internal Medicine
Moussawi, Khaled
M.D./Ph.D. Neurosciences
Massachusetts General Internal Medicine/Brigham &
Women’s – Neurology
Mullen, Thomas
M.D./Ph.D. MCBP
Lemuel Shattuck Hospital,
Boston - Transitional
Year/University of Washington Radiation Oncology
Rhome, Ryan
M.D./Ph.D. Biochemistry &
Molecular Biology
MUSC - Internal Medicine/Mt.
Sinai - Radiation Oncology
Sproul, Adrian
M.D./Ph.D. Neurosciences
MUSC Transitional Surgery,
NC/UNC - Chapel Hill –
Anesthesia
Andrijauskaite,
Kristina
M.S.
Biochemistry &
Molecular Biology
Obtaining a PhD’ continue
working in cancer research
Deepe, Raymond
M.S.
Microbiology &
Immunology
Unknown at the moment
Snider, Justin
M.S.
Biochemistry &
Molecular Biology
Transferring to Stony Brook to
complete PhD
Soderstrom, Lea
M.S.
Division of
Biostatistics &
Epidemiology
Completion of PhD at another
university
204
Post Graduation Plans
Bell, Guinevere
Ph.D.
Pharmaceutical
Sciences
Master Educator Training
Program, Ross University
Broadwater, Margaret Ph.D.
Biochemistry &
Molecular Biology
Research Chemist NOAA
Brunelle, Stephanie
Ph.D.
MCBP
Postdoctoral position at the
University of Washington,
Seattle - Genomics Training
Grant Awarded
Cornelius, Monica
Ph.D.
Division of
Biostatistics &
Epidemiology
Employment
Fortress, Ashley
Ph.D.
Neurosciences
Postdoctoral Fellowship at
University of Wisconsin at
Milwaukee
Fowler, Elizabeth
Ph.D.
Pathology
Undecided
Freeman, Linnea
Ph.D.
Pharmacology
Postdoctoral position at
Pennington Biomedical
Research Center
Postdoctoral Fellowship, Stony
Brook University (3-6months);
Gandy, Kathryn Alexa Ph.D.
Orr
MCBP
Gao, Peng
Ph.D.
Pharmaceutical
Sciences
Unknown
Hoeferlin, L. Alexis
Ph.D.
Biochemistry &
Molecular Biology
Postdoc at Virginia
Commonwealth University
Kellner, Joshua
Ph.D.
Pathology
Postdoc with Dr. Zihai Li,
Medical University of South
Carolina
Lyon, Barbara
Ph.D.
MCBP
NSF-IRFP to work in T. Mock
Lab at UEA, Norwich UK
Martins da Palma,
Telma
Ph.D.
Microbiology &
Immunology
Postdoc in Lisbon, Portugal
Pava, Matthew
Ph.D.
Neurosciences
IRTA Fellowship in David
Lovinger’s Lab of NIAAA
205
Pruett, Nathanael
Ph.D.
MCBP
Position at the National Institute
of Health, Bethesda MD,
NIAMS - Lab of Molecular
Immunogenetics
Rapisardo, Michelle
Ph.D.
Microbiology &
Immunology
Postdoc in Steve Tomlinson’s
lab
Robertson, Rosanna
Ph.D.
Biochemistry &
Molecular Biology
Postdoctoral fellowship at St.
Jude Children’s Research
Hospital in the Department of
Structural Biology
Samuel, Glady
Ph.D.
MCBP
Pursuing Postdoc position
Sartor, Gregory C.
Ph.D.
Neurosciences
Postdoc at University of Miami
Miller School of Medicine
Smith, Matthew
Ph.D.
Pharmaceutical
Sciences
Law School, Patent Law
Tirodkar, Tejas
Ph.D.
MCBP
Applying for Postdoctoral
research
206
2011 – 2012 Dissertation and Thesis
Adnan Al-Ayoubi, Ph.D., Cell and Molecular Pharmacology
Advisor: Dr. Scott E. Eblen
ERK/MAP Kinase Phosphorylates SPF45 and Regulates its Splicing Activity: Insights
onto Phosphorylation-dependent and -independent Effects in Ovarian Cancer Cells
Kristina Andrijaskaite, M.S. Biomedical Sciences
Advisor: Dr. Daniel Fernandes
Biochemical Links between Hormonal Mediators of Psychological Stress and the
Expression on MUC1 in Prostate Cancer Cells
Guillermo Alberto De Angulo, M.S. in Clinical Research
Advisor: Dr. Robert Adams
Hematological, Physiologic and Anthropometric Variables Associated with Transcranial
Doppler (TCD) Ultrasound Velocity and Blood Pressure Analysis among Sickle Cell
Children and Adolescents with Abnormal TCD Velocity
Melissa Batchelor Aselage, Ph.D., Nursing
Advisor: Dr. Elaine J. Amella
Feasibility of Implementing a Web-based Dementia Feeding Skills Training Module for
Nursing Home Staff
Katherine Atassi, Ph.D., Nursing
Advisor: Dr. Lynne Nemeth
Adapting the PPRNet TRIP QI Model to Increase Colorectal Cancer Screening in
Primary Care: A Feasibility Study
DeAnna Andrea Baker, Ph.D., Microbiology and Immunology
Advisor: Dr. Gary Gilkeson
The Determination of Sphingosine kinase 1 in a Murine Model of Inflammatory Arthritis
Guinevere Hannah Bell, Ph.D., Pharmaceutical Sciences
Advisor: Dr. Kennerly Patrick
Transdermal and Oral dl-methylphenidate-ethanol interactions in C57BL/6J Mice
Margaret Holbrook Broadwater, Ph.D., Biochemistry & Molecular Biology
Advisor: Dr. John Schwacke
Computational Methods for the Differential Profiling of Triacyglycerols using RPHPLV/APCI-MS
Stephanie Alexandra Brunelle, Ph.D., Molecular & Cellular Biology & Pathobiology
Advisor: Dr. Fran Van Dolah
Cell Cycle Regulation in the Florida Red Tide Dinoflagellate, Karenia brevis
207
Monica Elise Cornelius, Ph.D., Biostatistics & Epidemiology
Advisors: Dr. Elisabeth Pickelsimer and Dr. Jeff Korte
PTSD and Substance Use Disorders Among Offenders: Examining the Effects of TBI,
Gender and Interpersonal Violence Victimization
Raymond Deepe, M.S. Biomedical Sciences
Advisor: Dr. Janardan Pandey
Immunoglobulin and Fcy Receptor Genes Influence the Control of HIV Replication and
the Progression of HIV Infection
Ashley Megan Fortress, Ph.D., Neuroscience
Advisor: Dr. Lotta Granholm-Bentley
Mechanisms for Cholinergic Degeneration and Cognitive Impairment in Aging and Down
Syndrome
Elizabeth Babb Fowler. Ph.D., Pathology
Advisors: Dr. Omar Moussa and Dr. Brad Schulte
Characterization of Current and Novel Biomarkers of Bladder Cancer
Linnea Ruth Freeman, Ph.D., Pharmacology
Advisor: Dr. Ann-Charlotte Granholm
Damaging Effects of a High Fat Diet to Hippocampal Morphology and Function
Kathryn Alexa Orr Gandy, Ph.D., Molecular & Cellular Biology & Pathobiology
Advisor: Dr. Lina Obeid
Role of the Sphingosine Kinase/Sphingosine 1-Phosphate Pathway in Growth
Factor/Cytokine Mechanisms of Cellular Regulation
Peng Gao, Ph.D., Pharmaceutical Sciences
Advisor: Dr. Charles Smith
Comparison of the Differential Roles for Sphingosine Kinase (SK) Isoenzymes in Tumor
Cells and Characterization of SK-isoenzyme Selective Inhibitors
Christopher Ryan Gault, Ph.D., Molecular and Cellular Biology and Pathobiology
Sphingosine Kinase 1 is an Essential Enzyme for Ras Oncogenesis
Linda Augusta Heffernan-Stroud, Ph.D., Molecular and Cellular Biology and
Pathobiology
Regulation of Sphingosine Kinase 1 is a Crucial Component of the p53 Tumor
Suppressor Pathway
208
Lauren Alexis Hoeferlin, Ph.D., Biochemistry and Molecular Biology
Advisor: Dr. Sergey Krupenko
Regulation of Cell Death Pathways by Folate Metabolism
Russell William Jenkins, Ph.D., Biochemistry and Molecular Biology
Advisor: Dr. Yusuf Hannun
Roles and Regulation of Secretory and Lysosomal Acid Sphingomyelinase
Joshua Nathan Kellner, Ph.D., Pathology and Laboratory Medicine
Advisor: Dr. Bradley Schulte
Induction of Hematopoietic Stem Cell Self-renewal and Maintenance Ex Vivo Through
Small Molecule Compounds
Theresa Gunter Lawson, Ph.D., Nursing
Advisor: Dr. Teresa Kelechi
The Role of Chlamydia trachomatis and Neisseria gonorrhea in Pharyngitis
Collette R. Loftin, Ph.D., Nursing
Advisor: Dr. Susan Newman
Diversity in Texas Nursing Programs: A Correlational Study of Supportive
Characteristics and Graduation of Underrepresented Minority Nursing Students
Barbara R. Lyon, Ph.D., Molecular & Cellular Biology & Pathobiology
Advisor: Dr. Giacomo DiTullio
A Proteomics Approach to Investigate the Physiology of Dimethylsulfoniopropionate
Production in the Sea-Ice Diatom, Fragilariopsis cylindrus
Telma Raquel Martins da Palma, Ph.D., Microbiology and Immunology
Advisor: Michael Nishimura
Tyrosinase Reactive T Cells Reject or Edit Established Human Melanomas in vivo
Jordan Asher Magarik, M.S. in Clinical Research
Advisor: Dr. Daniel Lackland
The reliability of applying the Alberta Stroke Program Early Computed-Tomography
Score (ASPECTS) to computed-tomography (CT) and computed-tomography-perfusion
images in acute ischemic stroke
Robin Dianna Evans Matutina, Ph.D., Nursing
Advisor: Dr. Teresa Kelechi
Educational Interventions for Middle School Students to Improve the Perception of
Nursing as a Future Career Choice
Robert Kane McCall, M.S. in Clinical Research
Advisor: Dr. Richard Silver
Relationship of Main Pulmonary Artery Diameter to Pulmonary Arterial Pressure in
Scleroderma Patients with and without Mild to Moderate Interstitial Fibrosis
209
Jill Marie Monfre, Ph.D., Nursing
Advisor: Dr. Teresa J. Kelechi
Symptom Intrusiveness, Chronic Conditions and Health-Related Quality of Life:
Development of Conceptual and Measurement Models
Khaled Moussawi, M.D./Ph.D., Neuroscience
Advisor: Dr. Peter Kalivas
Rewiring Cocaine Addiction: Reversing Cocaine-Induced Plasticity Inhibits Relapse to
Drug-Seeking
Thomas Drakeford Mullen, M.D./Ph.D., Molecular and Cellular Biology and
Pathobiology
Ceramide Synthases: Roles in Sphingolipid Metabolism and Programmed Cell Death
Matthew Pava, Ph.D., Neuroscience
Advisor: Dr. John Woodward
Behavioral and Physiological Neuroadaptations of the Endocannabinoid System
Following Chronic Treatment with Ethanol
Janet Widaman Primrose, Ph.D., Nursing
Advisor: Dr. Carolyn Jenkins
Survey of School Nurses on School Violence
Nathanael David Pruett
Ph.D., Molecular and Cellular Biology and Pathobiology
Advisor: Dr. Alexander Awgulewitsch
Topographic Hox Expression in Adult Vasculture
Michelle Rapisardo
Ph.D., Microbiology and Immunology
Advisor: Dr. Stephen Tomlinson
Modulating Complement Activation on Tumor Cells
Ryan Matthew Rhome, M.D./Ph.D., Biochemistry and Molecular Biology
Advisor: Dr. Maurizio Del Poeta
Localization of Glucosylceramide During Cryptococcus neoformans Infection Optimizes
Use as a Novel Anti-Fungal Target
Rosanna Morgan Robertson, Ph.D., Biochemistry & Molecular Biology
Advisor: Dr. Christopher Davies
Developing New Drug Targets in Neisseria Gonorrhoeae: Functional and Structural
Studies of AmiC, an N-acetylmuramyl-L-alanine amidase Required for Bacterial Cell
Separation
210
Glady Hazitha Samuel, Ph.D., Microbiology and Immunology
Advisor: Dr. Maria Trojanowska
Novel Mediators of TGFB Signaling Contribute to Scleroderma Fibrosis: Role of Protein
Phosphatase 2A and Acid Spingomyelinase
Gregory Charles Sartor, Ph.D., Microbiology and Immunology
Advisor: Dr. Gary Aston-Jones
Roles of Lateral Septum and Bed Nucleus of Stria Terminalis Circuits in Cocaine
Preference
Matthew Allen Smith, Ph.D., Pharmaceutical and Biomedical Sciences
Advisor: Dr. Rick Schnellmann
Calpain 10: Degradation and Role in Mitochondrial Dysfunction
Justin Michael Snider, M.S. Biomedical Sciences
Dr. Jacek Bielawski
Simultaneous Quantitative Analysis of Glucosylceramide and Galactosylceramide
Species by Supercritical Fluid Chromatography Tandem Mass Spectrometry
Adrian David Sproul, M.D./Ph.D., Neurosciences
Advisor: Dr. P. Darwin Bell
N-Methyl-D-Asportate Receptor Subunit NR3a Expression and
Function in Principal Cells of the Collecting Duct
Genevieve Marie Thul, Ph.D., Nursing
Advisor: Dr. Gail Gilden
Reliability of Vital Sign Evaluation Methods in Nursing Education
Tejas Shirish Tirodkar, Ph.D., Molecular and Cellular Biology and Pathobiology
Advisor: Dr. Christina Voelkel-Johnson
Role of Ceramide Synthase 6 in Sphingolipid Metabolism and TRAIL Sensitivity of
Colorectal Cancer Cells
Patricia L. Watkins, M.S. in Clinical Research
Advisor: Dr. Joseph Jenrette
The impact of pre-treatment PET on disease control and treatment decisions in
locoregionally advanced esophageal cancer patients treated with chemoradiotherapy
211
First Year Students
Name
Mohamad Adada
Jacob Bowers
Robert Cameron
Danielle Desjardins
Joseph Guy
Daniel Herr
Jamie Mills
Douglas Roberts-Wolfe
Achraf Shamseddine
Abdulmenem Almadani
Charles Bergman
Danielle Brandon
Beth Coughlin
Dion Foster
Danielle Justis
Eva Karam
Andrew Mather
Alexander Matthews
Kristoffer Rodriguez
Abeba Teklehaimanot
James Atkison
Sarah Barrett
Sarah Barry
William Buchta
Theresa Cantu
Christy Cassarly
April Cox
Melanie Davis
David De Hart
Ryan De Palma
Liqiong Fan
Abby Goodson
Jessica Hathaway
Jiangting Hu
Sara Johnson
Youxuan Li
Ellen McGlinchey
Rachel Moss
Aarti Narang
Elizabeth Payne
Jose Pena-Bravo
Thomas Powers
degree
sought
M.D./Ph.D.
M.D./Ph.D.
M.D./Ph.D.
M.D./Ph.D.
M.D./Ph.D.
M.D./Ph.D.
M.D./Ph.D.
M.D./Ph.D.
M.D./Ph.D.
M.S.
M.S.
M.S.
M.S.
M.S.
M.S.
M.S.
M.S.
M.S.
M.S.
M.S.
Ph.D.
Ph.D.
Ph.D.
Ph.D.
Ph.D.
Ph.D.
Ph.D.
Ph.D.
Ph.D.
Ph.D.
Ph.D.
Ph.D.
Ph.D.
Ph.D.
Ph.D.
Ph.D.
Ph.D.
Ph.D.
Ph.D.
Ph.D.
Ph.D.
Ph.D.
Undergraduate Institution
Degree
American University, Beirut
University of Utah
Davidson College
Boston University
University of Minnesota
University of Scranton
California State University
Hampshire College
American University, Beirut
King Saud University
Winthrop University
Tufts University
Charleston Southern
Elon University
Sewanee
University at Buffalo/SUNY
Addis Ababa University
University of Miami
Furman University
SUNY at Binghamton
University of Texas, San Antonio
Virginia Polytech Institute
University of South Florida
Penn State University
Anderson University
Kings College
Shanghai Second Med University
University of St. Francis
Nanjing Medical University
Wofford College
Southeast University
Connecticut College
Charleston Southern University
Guru Nanak Dev University
Wheaton College
University of Puerto Rico
Furman University
BS
BA
BS
BA
BA
BS
BS
BA
BS
MT
BS
BS
BS
BS
BS
BS
BS
BS
BS
BS
BS
BA
BS
BS
BS
BS
MS
BS
BS
BS
MCR
MS
BS
MS
BS
BH
BA
BS
MS
BS
BS
BS/BA
212
Stephen Roper
Chawarat
Rotejanaprasert
Kimberly Sauls
Matthew Scheffel
James Small
Justin Snider
Melissa Sokolosky
Delia Voronca
Jason Wheeler
Ph.D.
Texas Technical University
MS
Ph.D.
Ph.D.
Ph.D.
Ph.D.
Ph.D.
Ph.D.
Ph.D.
University of California Santa Cruz
Winthrop University
North Greenville College
GA Institute
Medical University of SC
East Carolina University
Medical University of South
Carolina
MS
BS
BS
BS
MS
MS
MS
Ph.D.
213
MD/MSCR
First Year Master of Clinical Research Students
Name
Melissa Allen
Undergraduate/Graduate/Institution
Furman University/ MUSC
Degree
BS
Meghana Ammapuram
Osmania University
B.Sc.
Sonia Ashrafi
University of Dhaka
MBBS
Madhura Athreya
Osmania University
B.Sc.
Aby Augustine
Kursk State Medical University
Diploma of
Specialist
(Medicine)
Brandon Barrett
University of SC/ MUSC
BS
Amrutha Baskaran
Tbiilisi State Medical University
Diploma of
Specialist
(Medicine)
Nidhi Behl
Punjab Technical University
B.Pharm.
Gajula Bhoomeshwar
Kakatiya University
B.Pharm.
Madhavi Bollineni
Sri Venkateswara Institute of Medical
Sciences
B.Sc. (Nursing)
Marques Bradshaw
Duke University
MD
Anusha Chakravarthl
Osmania University
BS
Veronica Chikkala
NTR University of Health Science
BDS
Anusha Chunduri
Jawaharlal Nehru Technological
University
B.Pharm.
Lv Krishna Dasyam
University
B.Sc.
Shanini Dimri
Hemwati Nandan Bahuguna Garhwal
University
B.Sc.
Prabhavathi Duraisami
Tamil Nadu Dr. M.G.R. Medical
University
B.Sc.
Merlyn George
Shri Ramachandra University
BDS
Masoud Ghazvinian
Islamic Azad University
MD
Andrew Goodwin
Suny Health Sciences Center
PMD
Sreedhar Gujja
Kakatiya University
B.Pharm.
Rama Hariharan
Anna University
B.Tech
(Biotechnology)
214
Angela Hawk
Medical College of Georgia
MD
Gini Ikwuezunma
University of Georgia/MUSC
BS
Oluwatosin Jaiyeoba
Amadu Bello University
MBBS
Mohammad Kamdar
SRM University
B.Tech
(Biotechnology)
Meet Karia
Osmania University
B.Pharm.
Narinder Kaur
National University of Singapore
B.Sc.
Rupnit Kaur
Baba Farid University of Health Science BDS
Gurinder Kaur
Punjab University
B.Sc.
Charmaine Khoo
National University of Singapore
B.Sc.
Raghuvamsi Kona
Acharya Nagarjuna University
B.Pharm.
Vimala Koritala
Sri Venkateswara Institute of Medical
Sciences
B.Sc. (Nursing)
Nirmala Kotharu
Andhra University
B.Sc.
Sandeep Kumar
Punjab University
B.Sc.
Kanthimathi
Kumaraswamy
Osmania University
MBBS
Balakrishna Kurva
Osmania University
B.Sc.
Durga Mandali
B.Sc.
Shelly Matthews
Mahatma Gandhi University
B.Sc.
Kimberly McHugh
Medical University of South Carolina
MD
Shikha Mehta
Baba Fand University of Health Science BAMS
Tejonmayi Middela
Sri Krishnadevaraya University
B.Sc.
Nitin Miglani
Rajiv Gandhi University of Health
Science
B.Pharm.
Nidhi Mittal
Gujarat University
B.Sc.
Upamanyu Modak
West Bengal University of Health
Sciences
B.Pharm.
Brianna Morabito
Medical University of South Carolina
Pharm D
Program
Shivendra Na
Punjab University
B.Sc.
V. vardhan Nelluri
Science
B.Pharm.
Abhishek Pandey
Science
B.Pharm.
215
Supriya Paripally
University
B.Pharm.
Kandarp Patel
Tver State Medical Academy
Diploma of
Specialist
(Medicine)
Chunyan Peng
Fudan University
MD
Vinod Petati
B.Sc. (Nursing)
Roberto Pisoni
University of Pavia
PMD
Nitin Pundir
Chaudhary Charan Singh University
B.Sc.
Hussein Rajab
King Saud University
PMD
Rayla Rajkumar
Visveswariah Technological University
B.E.
Padmavathi
Ramakrishnan
Anna University
B.Tech
(Biotechnology)
Lakshmi Rao
Science
B.Pharm.
Hirok Roy
Osmania University
B.Sc.
Syed Saleem
Sri Venkateswara University
B.Sc.
Girish Sane
St. Petersburg State Pediatric Medical
Academy
Diploma of
Specialist
(Medicine)
Shekhar Sarkar
Kakatiya University
B.Sc.
Vaibhav Shah
Semey State Medical University
Diploma of
Specialist
(Medicine)
Richa Sharma
Science
BDS
Prem Sharma
Chaudhary Charan Singh University
B.Sc.
Karimunnisa Sheik
Sri Krishnadevaraya University
B.Sc.
Abha Singh
Bangalore Medical College
MBBS
Amit Singh
Kurukshetra University
B.Sc.
Bo Soong
Management Center Inssbruck Austria
MS
Karthikeyan Srinivasan
Pondicherry University
B.Pharm.
Hiteshkumar Suhagiya
Tver State Medical Academy
Diploma of
Specialist
(Medicine)
Vinod Sunkara
Acharya Nagarjuna University
B.Sc.
216
Anusha Suresh
Anna University
B.Tech
(Biotechnology)
Madhuva Tadimeti
Osmania University
B.Sc.
Nichole Tanner
University of Miami
MD
Murari Uthayakumar
Anna University
B.Tech
(Biotechnology)
Chandralekha Vaishnaw
Bangalore University
B.Sc.
Shikha Varyah
Punjab University
B.Sc.
Haripriya Vayalpati
B.Sc. (Nursing)
Meenakshi Venkatapuram Osmania University
B.Sc.
Karthik Vipparthi
B.Sc. (Nursing)
Thomas Wilfred
Osmania University
B.Sc.
Daniel Williams
East TN State
MD
Chang Long Wu
Emory University
MD
De-cai Yu
Nanjing University
MD
217
College of Graduate Studies Faculty
Name
Title
Department
Assistant Professor
Professor
Assistant Professor
Associate Professor
Ophthalmology
Neurosciences
Biostatistics, Bioinformatics &
Epidemiology
College of Nursing
College of Nursing
FULL MEMBERS
Zsolt Ablonczy, Ph.D.
Robert J. Adams, MD
DeAnna Adkins, Ph.D.
Anthony J. Alberg, Ph.D.
Elaine J. Amella, BSN, PhD Associate Professor
Jeannette Andrews, Ph.D., Associate Professor
APRN, BC
Raymond F. Anton, MD
Distinguished
University Professor
Kelly M. Argraves, Ph.D.
Research Assistant
Professor
W. Scott Argraves, PhD
Professor
John Arthur, M.D., Ph.D.
Associate Professor
Gary Aston-Jones, Ph.D.
Professor
Carl Atkinson, Ph.D.
Research Assistant
Professor
Alexander Awgulewitsch,
Associate Professor
PhD
John Baatz, PhD
Associate Professor
David L. Bachman, MD
Professor
Lisa J. Bain, Ph.D.
Assistant Professor
Prabhakar Baliga, MD
Professor, Director of
Transplant Surgery
Narendra Banik, PhD
Professor
Jan Basile, MD
Professor
Deepak Bastia, Ph.D.
Donnelly Professor of
Biomedical Sciences
Daniel Bearden, PhD
Assistant Professor
Howard Becker, PhD
Professor
Paul R. Becker, PhD
Program Leader
Craig Beeson, PhD
Associate Professor
Phillip Darwin Bell, Ph.D.
Professor
218
Psychiatry & Behavioral Sciences
Cell Biology & Anatomy
MCBP (nephrology)
Neurosciences
Medicine - Gastroenterology
Pediatrics
Neurosciences
MCBP-Marine Biomedicine
Surgery
Neurosciences
Medicine
Medicine
Narayan Bhat, PhD
Joe B. Blumer, Ph.D.
Robert Boackle, PhD
Galina S. Bogatkevich,
M.D., Ph.D.
Heather Shaw Bonilha,
Ph.D. CCCC-SLP
John Bosso, PharmD
Mark Bowden, Ph.D., PT
Erika T. Brown, Ph.D.
Truman R. Brown, Ph.D.
Professor
Research Assistant
Professor
Professor
Professor
Neurosciences
Pharmacology
Assistant Professor
Professor
College of Health Prof.
Radiology and Radiological
Sciences
Neurosciences
Assistant Professor
Professor
Catalin V. Buhusi, Ph.D.
Associate Professor
Erika-Elisabeth Bullesbach, Associate Professor
PhD
Karen G. Burnett, Ph.D.
Research Associate
Professor
Louis E. Burnett, Ph.D.
Professor
Maria Gordon Buse, MD
Distinguished
Matthew J. Carpenter,
Associate Professor
Ph.D.
Donald Castell, MD
Professor
Julie Chao, PhD
Professor
Lee Chao, PhD
Professor
Robert W. Chapman, PhD Assistant Professor
Jane M. Charles, Ph.D.
Associate Professor
Kenneth Chavin, MD, PhD Professor
Marc Chimowitz, MD
Professor
Steven Christopher, Ph.D. Research Chemist
Harry S. Clarke, Jr., MD,
Professor
Ph.D.
David J. Cole, MD
Professor
James Cook, PhD
Professor
George Cooper, MD
Distinguished
Luciano Costa, M.D., Ph.D. Assistant Professor
219
Stomatology
Division of Rheumatology &
Immunology
Medicine - Endocrinology
Medicine
Pediatrics
Surgery
Neurosciences
Department of Urology
Surgery
Neurosciences
Medicine, Cardiology - VAH
Hematology/Oncology Division
L. Ashley Cowart, Ph.D.
Kim E. Creek, Ph.D.
Craig Crosson, PhD
Research Assistant
Professor
Professor
Professor & Vice
Chairman For
Research
Ophthalmology
Rosalie Kelsey Crouch,
Professor
PhD
Joan E. Cunningham, Ph.D. Research Assistant
Professor
Vincent R. Dammai, PhD
Research Assistant
Professor
Christopher Davies, PhD
Associate Professor
Warren Davis, Ph.D.
Assistant Professor
Maurizio Del Poeta, MD
Associate Professor
Mark H. DeLegge, MD
Professor
Thomas A. Dix, PhD
Associate Professor
Jennifer L. Donovan, Ph.D. Research Assistant
Professor
Gregory J. Doucette, PhD
Assistant Professor
Harry Drabkin, MD
Professor
Christopher Drake, PhD
Associate Professor
Richard R. Drake, Ph.D.
Professor
MCBP
Robert Draughn, D.Sc.
Dental Medicine, Biophysical
Dentistry
Otolaryngology
Epidemiology
Pharmacology
College of Nursing
Pharmacology
Medicine
Division of Pulmonary and Critical
Care Medicine
Professor
Judy Dubno, PhD
Valerie L. Durkalski, Ph.D.
Professor
Research Assistant
Professor
Scott T. Eblen, Ph.D
Assistant Professor
Barbara Edlund, BSN, PhD Associate Professor
Brent Egan, MD
Professor
Leonard Egede, PhD
Assistant Professor
Weimin Fan, MD
Professor
Daniel Fernandes, PhD
Professor
Patrick Flume, M.D.
Professor
220
Epidemiology
Pharmacology
Medicine/SPTCR
Medicine
Department of Cell and Molecular
Pharmacology and Experimental
Therapeutics
Marvella E. Ford, PhD
Associate Professor
Department of Biostatistics,
Bioinformatics and Epidemiology
Associate Director of Cancer
Disparities, Hollings Cancer
Bruce M. Frankel, Ph.D.
Elizabeth Garrett-Mayer,
Ph.D.
Sebastiano Gattoni-Celli,
MD
Mulugeta Gebregziabher,
Ph.D.
Andrew K. Gelasco, Ph.D.
Robert M. Gemmill, Ph.D.
Mark George, MD
Gary Gilkeson, MD
Gail Barbosa Gliden, ScD,
RN
Robert G. Gourdie, Ph.D.
Eric Matthew Graham, M.D.
Lotta Granholm-Bentley,
Ph.D
Raymond S. Greenberg,
MD, PhD
Chris Gregory, Ph.D.
Associate Professor
Associate Professor
Neurosurgery
Epidemiology
Radiation Oncology
William Griffin, Ph.D.
Assistant Professor
Janet Grossman, DNSc
Louis J. Guillette, Ph.D.
Associate Professor
Distinguished
Professor
Professor of the
Howard Hughes
Medical Institute
Dean, College of
Graduate Studies
Professor,
Department of
Pharmacology
Assistant Professor
Perry Halushka, PhD, MD
Hiroko Hama, PhD
Professor
Assistant Professor
Assistant Professor
Professor
Professor
Professor
Associate Professor
Epidemiology
Medicine
Medicine
Medicine
College of Nursing
Associate Professor
Associate Professor
Professor, Director,
Center on Aging
President, Professor
Department of Pediatrics
Neurosciences
Assistant Professor
Doctoral Program in Health and
Rehabilitation Science
Center for Drug and Alcohol
Programs
Institute of Psychiatry
College of Nursing
221
President
Pharmacology
Samar Hammad, Ph.D.
Stanley Hoffman, PhD
Research Assistant
Professor
Professor and Chair
Assistant Professor
Professor
Professor
Assistant Professor
Distinguished
Professor
Philip H. Howe, Ph.D.
Yan Huang, MD, PhD
Walter Huda, Ph.D.
Thomas C. Hulsey, Sc.D.
Kelly J. Hunt, Ph.D.
Professor
Associate Professor
Professor
Professor
Assistant Professor
Shahid Husain, Ph.D.
Taisen Iguchi, Ph.D.
John Ikonomidis, MD, PhD
Ayad Jaffa, PhD
Eric James, PhD
Edward C. Jauch, MD, MS,
FACEP FAHA
Lankupalle D. Jayanthi,
Ph.D.
Carolyn Jenkins, MSN, PhD
Dorothea Jenkins, MD
Jens H. Jensen, Ph.D.
Jeffrey A. Jones, Ph.D.
Assistant Professor
Professor
Associate Professor
Assistant Professor
Professor
Associate Professor
Associate Professor
Radiology & Radiological Sciences
Epidemiology
Medicine, Division of
Rheumatology & Immunology
Medicine
Radiology
Pediatrics
Epidemiology
Ophthalmology
Surgery
Pharmacology
Medicine - Endocrinology
Ophthalmology
Division of Emergency Medicine
Assistant Professor
Neurosciences
Professor
Associate Professor
Professor
Research Assistant
Professor
Professor
Professor
Professor and Chair
Assistant Professor
Assistant Professor
Assistant Professor
College of Nursing
Pediatrics
MCBP
Neurosciences
Neurosciences
Medicine-Rheumatology
Division of Hematology/Oncology
Neurosciences
Yusuf A. Hannun, MD
Azizul Haque, Ph.D.
Debra Hazen-Martin, PhD
Joseph A. Helpern, Ph.D.
Mirko Hennig, Ph.D.
David G. Hoel, PhD
Walter Jones, PhD
Jane Joseph, Ph.D.
Peter W. Kalivas, PhD
Diane L. Kamen, M.D.
Yubin Kang, M.D.
Prakash Kara, Ph.D.
222
Medicine
Teresa Kelechi, PhD
Christine B. Kern, Ph.D.
Associate Professor
Assistant Professor
Janice D. Key, Ph.D.
Lyndon Key, MD
J. Michael Kilby, M.D.
Mark Kindy, PhD
Keith L. Kirkwood, D.D.S.,
Ph.D.
Richard Klein, PhD
Daniel Knapp, PhD
Associate Professor
Professor
Professor
Professor
Professor
Associate Professor
Associate Professor
Distinguished
Director, MUSC
Proteomics Center
Medicine
Pharmacology
Rebecca Knapp, PhD
Professor
Jeffrey E. Korte, Ph.D.
Assistant Professor
Yiannis Koutalos, PhD
Andrew S. Kraft, M.D.
James S. Krause, PhD
Stephen Kresovich, PhD
Associate Professor
Professor
Professor
Professor
Steven Kubalak, PhD
John Kucklick, PhD
Dhandapani Kuppuswamy,
PhD
David Kurtz, PhD
Martine LaBerge, Ph.D.
Professor
Associate Professor
Research Biologist
Associate Professor
Epidemiology
Epidemiology
Ophthalmology
Medicine
Vice President for Research and
Graduate Education
Medicine, Cardiology
Eric R. Lacy, PhD
Professor
Janice M. Lage, MD
Marilyn Laken, MSN, PhD
Stephen M. Lanier, Ph.D.
Amanda C. LaRue, Ph.D.
Professor and Chair
Professor
Professor
Assistant Professor
Professor
Professor
Professor
223
College of Nursing
Regenerative Medicine and Cell
Biology
Pediatrics
Pediatrics
Neurosciences
Pharmacology
Clemson Bioengineering
Epidemiology
Marine Biomedicine and
Environmental Science Center
College of Nursing
Pharmacology
Medicine
Andrew B. Lawson, Ph.D.
Associate Professor
Professor
John J. Lemasters, M.D.,
Ph.D.
Zihai Li, M.D., Ph.D.
Professor
Maria Lopes-Virella, MD,
PhD
Chiara Luberto, Ph.D.
Chair and Associate
Professor
Professor
Neurosciences
Epidemiology
Immunology & Cancer Immunology
Medicine
Research Assistant
Professor
Professor
Associate Professor
Director, Health
Services
Professor
Professor
Assoc. Dean for
Continuing Medical
Education
Otolaryngology
Bioinformatics & Epidemiology
Patrick Mauldin, Ph.D.
Professor
Associate Professor
Research Assistant
Professor
Associate Professor
Harold D. May, PhD
Paul J. McDermott, PhD
Jacqueline F. McGinty, PhD
Donald R. Menick, PhD
Peter M. Miller, Ph.D.
Jacobo Mintzer, M.D.
Maralynne Mitcham, PhD
Corey H. Mjaatvedt, PhD
Peter Moeller, PhD
Martin Morad, Ph.D.
William P. Moran, MD
Associate Professor
Professor
Professor
Professor
Professor
Professor
Professor
Associate Professor
Assistant Professor
Professor
Professor
Louis M. Luttrell, M.D.,
Ph.D.
Kathryn Magruder, PhD
Arch Mainous, III, PhD
Robert Malcolm, MD
Roger R. Markwald, PhD
Bonnie Martin-Harris, PhD
Renee’ H. Martin, Ph.D.
224
Medicine
Family Medicine
Epidemiology
Medicine, Cardiology
Neurosciences
Medicine - Cardiology
Regenerative Medicine
Division of General Internal
Medicine
Thomas A. Morinelli, Ph.D.
Steve Morton, Ph.D.
Andrew S. Mount, Ph.D.
Omar Moussa, Ph.D.
Robin Muise-Helmericks,
PhD
Patrick Mulholland, Ph.D.
Hugh Myrick, MD
Gavin Naylor, Ph.D.
Lynne S. Nemeth, Ph.D.
Carola Neumann, M.D.
Roger B. Newman, MD
Susan D. Newman, PhD,
RN, CRRN
Joyce S. Nicholas, PhD
Assistant Professor
Research Assistant
Professor
Assistant Professor
Assistant Professor
Assistant Professor
Associate Professor
Professor
Research Assistant
Professor
Assistant Professor
Professor
Assistant Professor
Assistant Professor
Anna-Liisa Nieminen, Ph.D. Associate Professor
Paul Nietert, Ph.D.
Assistant Professor
Michael Nishimura, Ph.D.
Associate Professor
Robert Sean Norman, Ph.D.
James S. Norris, PhD
Tamara Nowling, Ph.D.
Terrence X. O’Brien, PhD
Patrick O’Neil, Ph.D.
James Oates, MD
Jihad Obeid, M.D.
Professor
Assistant Professor
Associate Professor
Professor
Associate Professor
Associate Professor
Lina M. Obeid, MD
Makio Ogawa, MD, PhD
Besim Ogretmen, PhD
Steven M. Ornstein, MD
Yuko Y. Palesch, PhD
Professor
Professor
Associate Professor
Associate Professor
Professor
Janardan P. Pandey, PhD
Sunil J. Patel, M.D.
Professor
Professor
225
Medicine
MCBP
Neurosciences
College of Nursing
Pharmacology
Master Science in Clinical
Research
College of Nursing
Epidemiology
Medicine
College of Medicine
Institute of Psychiatry
Medicine/Rheumatology
Psychiatry and Behavioral
Sciences
Medicine
Medicine - VAH
Family Medicine
Epidemiology
Neurosciences
Kennerly S. Patrick, PhD
Georgi V. Petkov, Ph.D.
E. Elisabeth Pickelsimer,
Ph.D.
Etta Pisano, M.D.
Professor
Associate Professor
Research Assistant
Professor
Professor
David W. Ploth, MD
Charlene Pope, Ph.D.
Chandrakala Puligilla, Ph.D.
Sammanda Ramamoorthy,
PhD
Ann Ramsdell, PhD
Patrick K. Randall, Ph.D.
Professor
Assistant Professor
Assistant Professor
Associate Professor
Swapan K. Ray, Ph.D.
John R. Raymond, MD
Sakamuri V. Reddy, Ph.D.
Carolyn Reed, M.D.
Heidi Resnick, Ph.D.
J.G. Reves, MD
Assistant Professor
Research Assistant
Professor
Adjunct Professor
Professor
Professor
Professor
Professor
Professor
Epidemiology
Vice President for Medical Affairs
Dean, College of Medicine
Medicine - Nephrology
College of Nursing
Neurosciences
Neurosciences
Medicine
Medicine
Surgery
Anesthesia & Perioperative
Medicine
Neurosciences
Hematology/Oncology
Neurosciences
Pharmacology
Arthur Riegel, Ph.D.
Joelle Roche, Ph.D
Baerbel Rohrer, PhD
Steven A. Rosenzweig,
PhD
Eric S. Rovner, M.D.
Mark P. Rubinstein, Ph.D.
Michael E. Saladin, Ph.D
Paul A. Sandifer, PhD
J. Phillip Saul, M.D.
Michael G. Schmidt, PhD
Richard A. Schmiedt, PhD
Richard G. Schnellmann,
PhD
Assistant Professor
Professor
Associate Professor
Professor
Professor
Assistant Professor
Professor
Professor
Professor
Professor
Professor
Professor and Chair,
Department of
Pharmaceutical
Sciences
Health Sciences and Research
Neurosciences
U. Joseph Schoepf, M.D.
Associate Professor
Department of Radiology &
Radiological Science
226
Bradley A. Schulte, PhD
John H. Schwacke, Jr.,
Ph.D.
Lori Schwacke, Ph.D.
Geoffrey L. Scott, PhD
Professor
Assistant Professor
Ronald E. See, PhD
Anbesaw Selassie, PhD
Professor
Associate Professor
Suhua Sha, M.D.
Kelly G. Shaver, Ph.D.
Assistant Professor
Chair and Professor
Richard M. Silver, MD
Gerard Silvestri, M.D.
Kit N. Simpson, DrPH
Professor
Professor
Professor; Chair,
Department of Health
Administration and
Policy
Inderjit Singh, PhD
Leah Siskind, Ph.D.
Professor
Research Assistant
Professor
Associate Professor
Elizabeth H. Slate, PhD
Charles D. Smith, Ph.D.
Garriet Smith, PhD
Sheila Smith, Ph.D, RN,
LCCE, FACCE
Theresa Joanne Smith,
Ph.D.
Adam J. Smolka, PhD
David E. Soper, MD
Mark Sothmann, Ph.D.
Eleanor K. Spicer, PhD
Francis G. Spinale, MD,
PhD
Demetri D. Spyropoulos,
PhD
Charlton Strange, MD
Epidemiology
Research Associate Biometry & Epidemiology
Associate Professor, MCBP-Marine Biomedicine
Center Director
NOAA/NOS
Neurosciences
Epidemiology
Department of Management and
Entrepreneurship
School of Business
Medicine
Medicine
College of Pharmacy
Pediatrics
College of Medicine
Professor
Associate Professor
Assistant Professor
Epidemiology
College of Nursing
Associate Professor
Professor
Professor
Professor
Associate Professor
Professor
Medicine - Gastroenterology
Medicine - OB/GYN
Surgery
Associate Professor
Associate Professor
Medicine
227
Gail W. Stuart, PhD
Robert K. Stuart, M.D.
Natalie Sutkowski, PhD
Richard E. Swaja, Ph.D.
Michael Swindle, DVM
Kenneth D. Tew, Ph.D.
Bruce H. Thiers, MD
Robert P. Thompson, PhD
Stephen Tomlinson, PhD
Bryan P. Toole, Ph.D.
Frank Treiber, Ph.D.
Frances M. Van Dolah, PhD
Chenthamarakshan Vasu,
Ph.D.
Isabel Virella-Lowell, M.D.
Gabriel Virella, MD, PhD
Christina Voelkel-Johnson,
Ph.D.
Naren Vyavahare, Ph.D.
Carol Wagner, M.D.
Michael J. Wargovich,
Ph.D.
Dennis K. Watson, PhD
C. Kenneth Webb, Ph.D.
Andy Wessels, PhD
Caroline Westwater, PhD
Roger L. White, PharmD
M. Edward Wilson, M.D.
Dean, College of
Nursing; Professor
Professor
Assistant Professor
Professor
Professor
Chair, Department of
Cell & Molecular
Pharmacology &
Experimental
Therapeutics;
Professor
Professor
Professor
Professor
Professor
Professor
Assistant Professor
Associate Professor
Assistant Professor
Professor
Assistant Professor
Associate Professor
Associate Professor
Professor
Pharmacology
Professor
Assistant Professor
Associate Professor
Visiting Assistant
Professor
Professor
Professor of
Ophthalmology
228
Medicine
Comparative Medicine & Surgery
Pharmacology
Dermatology
MCBP
Health Sciences South Carolina
Center of Economic Excellence
Endowed Chair
Professor of Nursing & Medicine
Medicine, Division of
Ophthalmology
Richard N. Winn, Ph.D.
Cheryl M. Woodley, PhD
John Woodward, PhD
Robert Woolson, PhD
Associate Professor
Assistant Professor
Professor
Professor
Patrick M. Woster, Ph.D.
Cynthia F. Wright, PhD
Sharon Dziuba Yeatts,
Ph.D.
M. Rita Young, Ph.D.
Marian F. Young, Ph.D.
Jane Zapka, Sc.D.
Xian “John” Zhang, DVM,
PH.D.
Yong-Mei Zhang, Ph.D.
Wenle Zhao, Ph.D.
Professor
Associate Professor
Assistant Professor
Zhi Zhong, M.D., Ph.D
Michael R. Zile, MD
ASSOCIATE MEMBERS
Ronald Acierno, Ph.D.
Lawrence B. Afrin, MD
Berry Stephen Anderson,
Ph.D., RN
Andrew M. Atz, M.D.
Joan K. Austin, Ph.D., RN,
FAAN
Thierry Bacro, PhD
Sundaravadivel
Balasubramanian, Ph.D.
William S. Baldwin, Ph.D.
Lauren Ball, Ph.D.
Dipankar Bandyopadhyay,
Ph.D
Professor
Professor
Professor
Assistant Professor
Neurosciences
Epidemiology
Division of Biostatistics &
Epidemiology
Otolaryngology
MCBP
Biometry & Epidemiology
Assistant Professor
Research Assistant
Professor
Assistant Professor
Professor
Epidemiology
Professor
Associate Professor
Director of
Information
Technology, HCC
Assistant Professor
College of Nursing
Medicine
Professor
Distinguished
Professor Emerita
Associate Professor
Pediatrics
College of Nursing
Research Assistant
Professor
Associate Professor
Assistant Professor
Assistant Professor
229
College of Nursing
Regenerative Medicine and Cell
Biology
College of Medicine, Cardiology
Cell and Molecular Pharmacology
Epidemiology
Jeremy L. Barth, Ph.D.
Research Assistant
Professor
William T. Basco, Jr., M.D. Associate Professor
Sondra Berger, Ph.D.
Associate Professor
Alicja Bielawska, PhD
Associate Professor
Amy V. Blue, Ph.D.
Professor
Heather Anne Boger, Ph.D. Assistant Professor
Marcy Bolster, MD
Associate Professor
Sharon Bond, PhD., CNM
Associate Professor
Jeffrey J. Borckardt, Ph.D. Instructor
Keith Thomas Borg, MD,
Assistant Professor
PhD., FACEP
Deborah A. Bowlby, M.D., Assistant Professor
MSc
Alice Boylan, MD
Associate Professor
Amy Bradshaw, Ph.D.
Mona C. Buhusi, M.D.,
Ph.D.
Christine A. Byrum, Ph.D.
E. Ramsay Camp, M.D.
Laura Arnstein Carpenter,
Ph.D., BCBA
Sherine Chan, Ph.D.
Assistant Professor
Assistant Professor
C. James Chou, Ph.D.
Brian T Connor, Ph.D., RN
Brandon J. Cuthbertson,
PhD
Kimberly Davis, M.D.
Terry A. Day, M.D.
Kevin O. Delaney, M.D.
Assistant Professor
Assistant Professor
Marie DeLorenzo, PhD
Stacia DeSantis, Ph.D.
Assistant Professor
Assistant Professor
Vanessa A. Diaz, M.D.
Bonnie P. Dumas, Ph.D.
Mark Eckert, Ph.D.
Assistant Professor
Assistant Professor
Assistant Professor
Assistant Professor
Assistant Professor
Assistant Professor
Assistant Professor
Associate Professor
Associate Professor
Assistant Professor
230
Pediatrics
Medicine
Medicine
College of Nursing
Division of Emergency Medicine
Pediatric Endocrinology
Medicine - Pulmonary and Critical
Care
MCBP
Neurosciences
Division of Developmental
Pediatrics
Pharmaceutical and Biomedical
Sciences
College of Nursing
General Internal Medicine
Otolaryngology
Division of Plastic Surgery
MCBP-Marine
Epidemiology
Medicine
College of Nursing
Otolaryngology/Head & Neck Surg
Charles Ellis, Ph.D.
Nestor Felix Esnaola, M.D.,
M.P.H., M.B.A.
Hongkuan Fan, Ph.D.
Victoria Findlay, Ph.D.
Wayne Fitzgibbon, PhD
Dee Walker Ford, Ph.D.
Assistant Professor
Associate Professor
Assistant Professor
Research Assistant
Professor
Assistant Professor
Assistant Professor
Neurosciences
Medicine
Division of Pulmonary and Critical
Care
Esther Forti, RN, PhD
Associate Professor
Director, SC Geriatric
Education Center
Maria N. Garnovskaya,
Ph.D.
Marion Boyd Gillespie, M.D.
Laura Goetzl, MD
Monika Gooz, MD, PhD
Associate Professor
Neurology
Associate Professor
Assistant Professor
Instructor
David Graber, Ph.D.
Kevin M. Gray, M.D.
Dianne I. Greenfield, Ph.D.
Nigel H. Greig, Ph.D.
Tatyana Gudz, Ph.D.
Beichu Guo, Ph.D.
Dieter Haemmerich, Ph.D.
Phillip Hall, PhD
Kevin R Harris, Ph.D.
Courtney J. Haycraft, Ph.D.
Starr Hazard, PhD
Tilman Heise, Ph.D.
Frederick Heldrich, PhD
Associate Professor
Associate Professor
Assistant Professor
Senior Investigator
Assistant Professor
Assistant Professor
Assistant Professor
Associate Professor
Assistant Professor
Assistant Professor
Associate Professor
Assistant Professor
Professor
Kristi Helke, DVM, PhD
Assistant Professor
Melissa Howard Henshaw,
M.D.
Kristin Highland, M.D.
Elizabeth G. Hill, Ph.D.
Assistant Professor
Medicine
MCBP
Pharmacology
MCBP
Neurosciences
Neurosciences
Pediatrics
College of Nursing
Cell Biology & Anatomy/MCBP
Library Science
Dept of Chemistry, Univ of Chas
Biochemistry
Laboratory Animal Resources
Comparative Medicine
Pediatrics
Assistant Professor
Assistant Professor
231
Medicine
Epidemiology
Julie Hilsenbeck, RN, DNS,
CNRN
Anthony Hlavacek, MD,
FAAP
Lorne J. Hofseth, Ph.D.
Ann Hollerbach, PhD
Christine Holmstedt, D.O.
Yi-Te Hsu, PhD
Francis “Monty” Hughes,
Ph.D.
Peter van den Hurk, Ph.D.
Andrew Jakymiw, Ph.D.
Michael Janech, Ph.D.
Tariq Javed, DMD
Joseph M. Jenrette, M.D.
Thomas Jhou, Ph.D.
Donna Johnson, MD
Jordan V. Johnson, EdD,
SPHR
Qian Kay Kang, MD
College of Nursing
Assistant Professor
Pediatric Cardiology
Associate Professor
Associate Professor
Assistant Professor
Assistant Professor
Staff Scientist II
College of Nursing
Division of Neurology
Assistant Professor
Assistant Professor
Environmental Toxicology
Craniofacial Biology and Cancer
Biology
Medicine
Dental Medicine, Stomatology
Radiation Oncology
Neurosciences
Medicine
College of Nursing
Assistant Professor
Professor
Professor/Chairman
Assistant Professor
Associate Professor
Associate Professor
Assistant Professor
CU-MUSC Bioengineering
Program
Laura Kasman, Ph.D.
Assistant Professor
Abby Kazley, Ph.D.
Assistant Professor
Lydia King, Ph.D.
Assistant Professor
Pediatrics
Rachael King, Ph.D.
Program Coordinator, MCBP-Marine Biomedicine
Taxonomic Center
Emily Kistner-Griffin, Ph.D. Assistant Professor
Epidemiology
Satomi Kohno, Ph.D.
Assistant Professor
Masahiro Kono, PhD
Assistant Professor
Ophthalmology
Michelle Elaine Koski, M.D. Assistant Professor
Mary C. Kral, Ph.D.
Associate Professor Pediatrics
Edward Krug, PhD
Associate Professor Cell Biology and Anatomy
Hainan Lang, MD, Ph.D.
Assistant Professor
Angela LaRosa, Ph.D.
Associate Professor Pediatrics
Kyu-Ho Lee, MD, PhD
Assistant Professor
Peter Alan Lee, Ph.D.
Research Associate MCBP-Marine Biomedicine
Professor
232
John W. Leffler, Ph.D.
Renata Serricchio Leite,
D.D.S.
Elizabeth J. Letourneau,
Ph.D.
Xiang Liu, M.D., Ph.D.
Pamela Susan Lovelace,
Ph.D.
Dierdre K. Luttrell, Ph.D.
James E. Madory, D.O.
Gayenell S. Magwood,
Ph.D.
AnnaLaura Mancia, Ph.D.
Cungui Mao, Ph.D.
Margaret Markiewicz, Ph.D.
Gabriel U. Martz, M.D.
Meenal Mehrotra, Ph.D.
Shikhar Mehrotra, Ph.D.
Ted A. Meyer, M.D., Ph.D.
Michael Mitas, Ph.D.
Bidyut K. Mohanty, Ph.D.
Lawrence C. Mohr, MD
Janet G. Moore, Ph.D.
David Morrisette, Ph.D.
Steve Morton, PhD
Martina Mueller, Ph.D.
Rupak Mukherjee, PhD
Thomas Naselaris, Ph.D.
Brad W. Neville, D.D.S.
Shaun Nguyen, M.D., M.A.
Kenkichi Nozaki, M.D.,
Ph.D.
John E. Oatis, Jr., Ph.D.
Lawrence S. Olanoff, M.D.,
Ph.D.
Assistant Professor
Assistant Professor
SCDNR MRRI
Stomatology
Associate Professor
Assistant Professor
Adjunct Assistant
Professor
Research Assistant
Professor
Assistant Professor
Assistant Professor
Assistant Professor
Assistant Professor
Assistant Professor
Assistant Professor
Assistant Professor
Assistant Professor
Assistant Professor
Assistant Professor
Research Assistant
Professor
Professor
Medicine, Division of Nephrology
Pathology & Laboratory
Medicine/MSCR
College of Nursing
Medicine
Dept. of Neurosciences
Surgery
Surgery
Associate Professor
Project Leader
Assistant Professor
Associate Professor
Assistant Professor
Professor
Assistant Professor
Assistant Professor
Medicine
College of Nursing
Surgery
Neurosciences
Dental Medicine
Otolaryngology
Division of Neurology
Assistant Professor
Pharmacology
233
Viswanathan
Assistant Professor
Palanisamy, Ph.D.
Christopher H. Parsons, MD Assistant Professor
Dental Medicine
Yuri Karl Peterson, Ph.D.
Michelle Phillips Hudspeth,
M.D.
Craig J. Plante, PhD
Research Assistant
Professor
Assistant Professor
Medicine
Pediatrics
Professor, Director of MCBP-Marine Biomedicine
Marine Biology at
J. Todd Purves, M.D., Ph.D. Assistant Professor
Viswanathan
Professor
Ramakrishnan, Ph.D.
Paula Ramos, Ph.D
Assistant Professor
Biostatistics and Epidemiology
Anil G. Rao, M.D.
James G. Ravenel, MD
Michele Carter Ravenel,
DMD
Titus A. Reaves, Ph.D.
Deanna Reising, Ph.D, RN,
ACNS-BC, ANEF
Adrian Reuben, MBBS,
FRCP, FACG
Donna Roberts, M.D.
Assistant Professor
Associate Professor
Assistant Professor
Radiology & Radiological Sciences
Radiology
Stomatology
Associate Professor
College of Nursing
Professor
Christopher J. Robinson,
M.D., M.S.C.R.
Joseph Romagnuolo, M.D.,
M.Sc
Zoran Rumboldt, M.D.
Steven H. Saef, MD
Lisa Saladin, Ph.D., PT
Assistant Professor
Division of Gastroenterology &
Hepatology
Sciences
Obstetrics and Gynecology
Dennis Kenneth Schimpf,
M.D.
Rodney Schlosser, MD
Alison J. Scott, Ph.D.
Andrew Shedlock, Ph.D.
Associate Program
Director
Associate Professor
Assistant Professor
Assistant Professor
Assistant Professor
Professor
Associate Professor
Assistant Professor
Assistant Professor
234
Division of Rheumatology and
Immunology
College of Medicine
Gastroenterology and Hepatology
Radiology
Medicine/Emergency Medicine
College of Health Prof. - Physical
Therapy Program
Division of Plastic and
Reconstructive Surgery
College of Nursing
Department of Biology
Girish S. Shirali, MD
Associate Professor
Owen S Shoemaker, Ph.D. Assistant Professor
Tuulikki Sokka, MD, PhD
Research Assistant
Professor
Erik Sotka, Ph.D.
Assistant Professor
Jeremy Soule, MD
Assistant Professor
Eva Spratt, M.D.
Associate Professor
Ida Spruill, Ph.D., RN
Assistant Professor
Antine E. Stenbit, MD, PhD Assistant Professor
Katherine Regan Sterba,
Assistant Professor
Ph.D., MPH
Allan Strand, Ph.D.
Associate Professor
Sally Dawley Stroud, Ed.D., Associate Professor
APRN, BC
Rachel L. Sturdivant, M.D., Assistant Professor
FNKF
Yukiko Sugi, Ph.D.
Associate Professor
Joann F. Sullivan, PhD
Pal Suranyi, M.D., Ph.D.
Associate Professor
Assistant Professor
Cynthia Cupit Swenson,
PhD
Steven Edward Swift, M.D.
Associate Professor
David Taber, Ph.D.
Ali Tabesh, Ph.D.
Assistant Professor
Assistant Professor
Saeid Taheri, Ph.D.
Christine Tanner, PHD, RN,
FAAN
Irene Tessaro, DrPH, MSN
Baby Tholanikunnel, PhD
Assistant Professor
Distinguished
Professor
Research Professor
Assistant Professor
Suzanne Thomas, Ph.D.
Elena Tourkina, Ph.D.
Associate Professor
Research Assistant
Professor
Research Assistant
Professor
Danyelle M. Townsend,
Ph.D.
Professor
235
Pediatrics
Epidemiology
Medicine
Pediatrics
College of Nursing
Medicine
Epidemiology
College of Nursing
Division of Nephrology
Regenerative Medicine & Cell
Biology
Library
Department of Radiology and
Radiological Science
Department of Obstetrics and
Gynecology
College of Pharmacy
Science
Department of Radiology
College of Nursing
College of Nursing
Epidemiology
College of Nursing
MCBP
Heather TranthamDavidson, Ph.D.
Rupal H. Trivedi, MD
Research Assistant
Professor
Research Assistant
Professor
Tanya N. Turan, M.D.
Assistant Professor
David Turner, Ph.D.
Research Assistant
Professor
Abhay K. Varma, M.B.B.S. Assistant Professor
Diana J. Vincent, PhD
Associate Professor
Richard P. Visconti, Ph.D. Assistant Professor
John Vournakis, Ph.D.
Professor
David T. Vroman, MD
Associate Professor
Hongjun Wang Ph.D.
Associate Professor
Patricia Watson, PhD
Assistant Professor
C. Wayne Weart, Pharm.D. Professor
Xuejun Wen, Ph.D., M.D.
Assistant Professor
Maria Kathleen Wiley, M.D. Associate Professor
Pamela Holtzclaw Williams, Assistant Professor
JD, PHD, RN
Daynna J. Wolff, PhD
Associate Professor
Julie Ann Woolworth, Ph.D.
Michael D. Wyatt, Ph.D.
Associate Professor
W. Jim Zheng, Ph.D.
Assistant Professor
Jun Zhu, Ph.D.
Yusheng Zhu, PhD
Anastasia Maria
Zimmerman, Ph.D.
James Zoller, Ph.D., MHA
Assistant Professor
Assistant Professor
Assistant Professor
Associate Professor
236
Neurosciences
Ophthalmology
Neurosciences
Division of Neurosurgery
Radiology
Medicine
Ophthalmology
Medicine
College of Pharmacy
Internal Medicine
College of Nursing
Epidemiology
College of Charleston Department
of Biology
College of Health Profession

College of Graduate Studies Annual Report 2011-2012

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