TEST CHANGE ALERT #372 April 25, 2011

TEST CHANGE ALERT
#372
April 25, 2011
Summary Of Changes
TestCode(s)
Test Description
AA.QUANT (AAQ) .....AMINO ACIDS, QUANT, PLASMA (Note & Specimen Requirements)
AAQTCA ...................................AMINO ACIDS QUANTITATIVE, CSF (New)
AAQTPA ...............................AMINO ACIDS, QUANTITATIVE, PLASMA (New)
AAQTUA ........................................AMINO ACIDS QUANT, URINE (New)
AAU.QUANT (AAURQ) ...........................AMINO ACIDS, QUANT, URINE (Note)
ACETONE (KET) ......................ACETONE (SERUM) (Method, Reference Range)
ACMPS .................................ACID MUCOPOLYSACCHARIDES, URINE (Note)
ARTHID .................................................ARTHROPOD ID (Delete)
CC1QSM ..................................................COMPLEMENT C1Q (New)
CHROMA .............................................CHROMOGRANIN A (See Note)
COBABA ...................................................COBALT, BLOOD (New)
COBAUA ...................................................COBALT, URINE (New)
CORUFA .......................CORTISOL/CORTISONE URINE FREE (Reference Range)
CPPCR .............................CHLAMYDOPHILA PNEUMONIAE DNA QUAL (Delete)
CULT.FLD (CFL) .........................CULTURE, BODY FLUID, REFLEX (Volumes)
GLUTAMINE (GLUTSF) ....................................GLUTAMINES, CSF (Note)
HAMAF .......................................HUMAN ANTI-MOUSE AB (HAMA) (New)
HBSAG.NEUT (NHBSAG) .........................HBSAG BY NEUTRALIZATION (Delete)
HBYGA .......................................HEPATITIS B VIRUS GENOTYPE (New)
HCRIBA ..................................HEPATITIS C AB BY RIBA (Please Note)
HEXALM ...........HEXOSAMINIDASE A & TOTAL, LEUKOCYTE (Reference Range Units)
HGH ............................HGH (HUMAN GROWTH HORMONE) (Reference Range )
HTLYWB .............................HTLV-I/II ANTIBODY, WESTERN BLOT( Delete)
IL1BA .......................................INTERLEUKIN 1 BETA BY MAFD (New)
IMI (IMDES) ........................IMIPRAMINE & METABOLITE (Reference Range)
MAPRLA ..................................................MACROPROLACTIN (New)
METABOLIC.SCR (METSUR) ...............................METABOLIC SCREEN (Note)
METMB ........................METHADONE & META, SERUM (Specimen Requirements)
MPQTUA ...............................MUCOPOLYSACCHARIDES, QUANT, URINE (New)
MYEGF ..............................................MYELIN IGG ANTIBODY (New)
NMOCM ...........................NEUROMYELITIS OPTICA AUTOAB IGG CSF (Delete)
NMOIG ...............................NEUROMYELITIS OPTICA NMO AB IGG (Delete)
OBGA .............................................OCCULT BLOOD, GASTRIC (New)
ORAU ..............................................ORGANIC ACIDS URINE (Note)
ORAURA ............................................ORGANIC ACIDS, URINE (New)
PARID ......................PARASITE ID (MACROSCOPIC) (Specimen Requirements)
PTHINT ...............................PTH INTACT NO CALCIUM (Critical Frozen)
RNAPAA ......................................RNA POLYMERASE III AB, IGG (New)
SS.LAP (LAP) .....................LEUK ALK PHOS STAIN (Specimen Requirements)
TESTFW ..................................TESTOSTERONE WEAKLY BINDING (Delete)
TYSABF ..............................................TYSABRI ANTIBODIES (New)
VAN .......................................VANCOMYCIN (Specimen Requirements)
VAN.PK (VANCPK) .....................VANCOMYCIN, PEAK (Specimen Requirements)
VAN.TR (VANCTR) ...................VANCOMYCIN, TROUGH (Specimen Requirements)
VAN2 (VANIN) ..............VANCOMYCIN (PEAK & TROUGH) (Specimen Requriements)
VIPCG .......................C.TRACHOMATIS/N.GONORRHOEAE SDA/PAP (CPT Coding)
VITB5A ...................................VITAMIN B5 (PANTOTHENIC ACID) (New)
VITB7A .............................................VITAMIN B7 (BIOTIN) (New)
VORIF .........................................VORICONAZOLE LEVEL, HPLC (New)
PAML TEST CHANGE ALERT #372 page: 2
TEST CHANGE ALERT
#372
April 25, 2011
The following tables reflect revisions only; other existing data remain unchanged.
AA.QUANT
AAQ
order code
flexilab code
Effective
Specimen
Requirements
Please Note
1 mL frozen sodium heparin plasma (green top tube). Separate plasma from cells and put in separate
plastic tube and freeze. Store and transport frozen.
This test will be for internal use only.
order code
AAQTCA
flexilab code
Effective
05/24/2011
Method
Ion Exchange Chromatography
Specimen
Requirements
Comments
Requirements)
05/24/2011
AAQTCA
CPT4
AMINO ACIDS, QUANT, PLASMA (Note & Specimen
AMINO ACIDS QUANTITATIVE, CSF (New)
82139
0.5 mL frozen CSF. Collect CSF and put in a leakproof plastic tube. Centrifuge CSF to separate and
remove cellular material. Put CSF in a separate leakproof plastic tube and freeze immediately. Store and
transport frozen. CRITICAL FROZEN. If multiple tests are ordered separate specimens must be submitted.
Complete a patient history for biochemical genetic testing form available at www.aruplab.com for test code
0080137 and include with specimen.
1) Min Amt: 0.3 mL. 2) Stability: RT-unacceptable, Refrigerated-24 hours, Frozen-1 month. 3) ARUP#
0080137.
Reference
Ranges
Amino Acids,
CSF, Interp
Alanine, CSF
Arginine, CSF
Asparagine,
CSF
Aspartate, CSF
Citrulline,
CSF
Cystine, CSF
Glutamine, CSF
Glutamic Acid
CSF
Glycine, CSF
Histidine, CSF
Homocystine,
CSF
Hydroxyproline
CSF
Isoleucine,
CSF
Leucine, CSF
Lysine, CSF
Normal
12.5-47.3
5.9-30.6
0.0-23.6
umol/L
umol/L
umol/L
0.0-5.6
0.0-5.6
umol/L
0.0-5.0
230.7-637.4
0.0-15.0
umol/L
umol/L
3.1-21.0
5.0-24.0
0.0
umol/L
umol/L
umol/L
0.0-8.0
umol/L
1.0-11.0
umol/L
3.4-25.9
7.8-40.8
umol/L
umol/L
PAML TEST CHANGE ALERT #372 page: 3
Methionine,
CSF
Ornithine, CSF
Phenylalanine,
CSF
Proline, CSF
Serine, CSF
Taurine, CSF
Threonine, CSF
Tyrosine, CSF
Valine, CSF
AAQTPA
order code
AAQTPA
flexilab code
Effective
05/24/2011
Method
Ion Exchange Chromatography
CPT4
Specimen
Requirements
Comments
0.4-9.4
umol/L
1.6-12.0
6.9-25.1
umol/L
umol/L
0.0-8.0
18.0-73.0
2.7-16.2
10.8-74.9
5.4-23.7
7.0-37.1
umol/L
umol/L
umol/L
umol/L
umol/L
umol/L
AMINO ACIDS, QUANTITATIVE, PLASMA (New)
82139
0.5 mL frozen lithium or sodium heparin plasma (green top tube). Separate plasma from cells ASAP and
avoid collecting buffy coat material and put in a separate plastic tube and freeze ASAP. Fasting draw
recommended for adults; for infants and children a pre-feed sample or a sample drawn 2-3 hours after a
meal. CRITICAL FROZEN. Separate samples must be drawn if multiple tests are ordered. Complete a
patient history for biochemical genetics form avaliable at www.aruplab.com for test 0080710 and send with
sample.
1) Min Amt: 0.25 mL. 2) Unacceptable conditions: hemolyzed specimens and samples received at room
temperature. 3) Stability: RT-unacceptable, Refrigerated-24 hours, Frozen-1 month. 4) ARUP# 0080710.
Reference
Ranges
Amino Acids,
Plasma Interp
Alanine
Allo-isoleucine
Arginine
Aspartic Acid
Citrulline
Cystine
Glutamic Acid
Glutamine
Glycine
Histidine
Homocystine
Hydroxyproline
Normal
0-11
1 yr
0-11
1 yr
0-11
1 yr
0-11
1 yr
0-11
1 yr
0-11
1 yr
0-11
1 yr
0-11
1 yr
0-11
1 yr
0-11
1 yr
0-11
1 yr
0-11
mo
+
mo
+
mo
+
mo
+
mo
+
mo
+
mo
+
mo
+
mo
+
mo
+
mo
+
mo
200-600
240-600
None Detected
None Detected
20-160
40-160
0-40
0-20
6-60
10-60
7-70
7-70
10-190
10-120
410-960
410-700
220-520
140-490
40-120
50-130
None Detected
None Detected
6-90
umol/L
umol/L
umol/L
umol/L
umol/L
umol/L
umol/L
umol/L
umol/L
umol/L
umol/L
umol/L
PAML TEST CHANGE ALERT #372 page: 4
Isoleucine
Leucine
Lysine
Methionine
Ornithine
Phenylalanine
Proline
Serine
Taurine
Threonine
Tyrosine
Valine
AAQTUA
order code
1 yr
0-11
1 yr
0-11
1 yr
0-11
1 yr
0-11
1 yr
0-11
1 yr
0-11
1 yr
0-11
1 yr
0-11
1 yr
0-11
1 yr
0-11
1 yr
0-11
1 yr
0-11
1 yr
+
mo
+
mo
+
mo
+
mo
+
mo
+
mo
+
mo
+
mo
+
mo
+
mo
+
mo
+
mo
+
AAQTUA
flexilab code
Effective
05/24/2011
Method
Ion Exchange Chromatography
CPT4
Specimen
Requirements
Comments
6-50
20-130
30-130
40-230
60-230
60-250
80-250
10-60
17-53
20-135
20-135
30-100
30-80
110-500
110-500
90-250
60-200
25-160
25-80
50-300
60-220
30-140
30-120
110-300
140-350
umol/L
umol/L
umol/L
umol/L
umol/L
umol/L
umol/L
umol/L
umol/L
umol/L
umol/L
umol/L
umol/L
AMINO ACIDS QUANT, URINE (New)
82139
10 mL frozen random urine specimen. First morning urine preferred. Collect a random urine in a leakproof
plastic urine container. Avoid dilute urine when possible. ASAP after urine collection, mix the collection,
aliquot 10 mL urine and freeze. Critical Frozen. Store and transport frozen. Separate specimens must be
submitted when multiple tests are ordered. Complete the patient history for biochemical genetic testing
form available at www.aruplab.com for test code 0080044 and submit with specimen.
1) Min Amt: 2 mL. 2) Stability: RT-unacceptable, Refrigerated-24 hours, Frozen-1 month. 3) ARUP#
0080044.
Reference
Ranges
Creatinine, Ur
Amino Acids,
Ur Interp
Alanine, Ur
Arginine, Ur
0-5 mo
6-11 mo
1-3 yrs
4-12 yrs
13 yrs+
0-5 mo
6-11 mo
1-3 yrs
4-12 yrs
mg/dL
mg/dL
637-2159
319-1434
292-1151
151-814
142-602
0-124
0-97
0-80
0-62
umol/g
umol/g
PAML TEST CHANGE ALERT #372 page: 5
Asparagine, Ur
Aspartic Acid,
Ur
Citrulline, Ur
Cystine, Ur
Glutamic Acid,
Ur
Glutamine, Ur
Glycine, Ur
Histidine
Ur
Homocystine,
Ur
Hydroxyproline
, Ur
Isoleucine, Ur
Leucine, Ur
13 yrs +
0-5 mo
6-11 mo
1-3 yrs
4-12 yrs
13 yrs +
0-5 mo
6-11 mo
1-3 yrs
4-12 yrs
13 yrs+
0-5 mo
6-11 mo
1-3 yrs
4-12 yrs
13 yrs+
0-5 mo
6-11 mo
1-3 yrs
4-12 yrs
13 yrs+
0-5 mo
6-11 mo
1-3 yrs
4-12 yrs
13 yrs+
0-5 mo
6-11 mo
1-3 yrs
4-12 yrs
13 yrs+
0-5 mo
6-11 mo
1-3 yrs
4-12 yrs
13 yrs+
0-5 mo
6-11 mo
1-3 yrs
4-12 yrs
13 yrs+
0-5 mo
6-11 mo
1-3 yrs
4-12 yrs
13 yrs+
0-5 mo
6-11 mo
1-3 yrs
4-12 yrs
13 yrs+
0-5 mo
6-11 mo
1-3 yrs
4-12 yrs
13 yrs+
0-5 mo
0-44
0-743
0-319
0-283
0-257
0-204
18-142
27-106
18-89
9-89
18-62
0-97
0-71
53-186
0-44
0-35
0-97
53-133
53-186
35-106
27-151
0-266
0-159
0-97
0-80
0-106
460-2027
655-1744
398-2089
177-1177
177-673
1859-9709
1009-3938
974-3151
566-2177
381-1531
638-3027
814-2460
602-2540
381-1912
230-1354
Not Detected
Not Detected
Not Detected
Not Detected
Not Detected
0-2832
0-195
0-115
0-115
0-115
0-53
0-53
0-53
0-53
0-35
27-221
umol/g
umol/g
umoL/g
umol/g
umol/g
umol/g
umol/g
umol/g
umol/g
umol/g
umol/g
umol/g
PAML TEST CHANGE ALERT #372 page: 6
Lysine, Ur
Methionine, Ur
Ornithine, Ur
Phenylalanine,
Ur
Proline, Ur
Serine, Ur
Taurine, Ur
Threonine, Ur
Tyrosine, Ur
Valine, Ur
6-11 mo
1-3 yrs
4-12 yrs
13 yrs+
0-5 mo
6-11 mo
1-3 yrs
4-12 yrs
13 yrs+
0-5 mo
6-11 mo
1-3 yrs
4-12 yrs
13 yrs+
0-5 mo
6-11 mo
1-3 yrs
4-12 yrs
13 yrs+
0-5 mo
6-11 mo
1-3 yrs
4-12 yrs
13 yrs+
0-5 mo
6-11 mo
1-3 yrs
4-12 yrs
13 yrs+
0-5 mo
6-11 mo
1-3 yrs
4-12 yrs
13 yrs+
0-5 mo
6-11 mo
1-3 yrs
4-12 yrs
13 yrs+
0-5 mo
6-11 mo
1-3 yrs
4-12 yrs
13 yrs+
0-5 mo
6-11 mo
1-3 yr
4-12 yrs
13 yrs +
0-5 mo
6-11 mo
1-3 yrs
4-12 yrs
13 yrs+
35-142
27-159
27-142
27-97
133-1761
115-699
89-611
89-602
62-513
53-239
71-257
44-257
35-177
18-142
0-168
0-71
0-71
0-62
0-44
35-283
97-248
62-274
44-230
27-168
0-1885
0-124
0-80
0-80
0-80
372-2496
443-1213
283-1097
204-823
186-443
53-2000
80-1089
106-1770
151-2036
142-1593
151-1221
124-496
89-549
80-319
62-257
53-487
97-478
89-425
53-310
27-204
27-230
53-168
0-71
27-151
27-115
umol/g
umol/g
umol/g
umol/g
umol/g
umol/g
umol/g
umol/g
umol/g
umol/g
PAML TEST CHANGE ALERT #372 page: 7
AAU.QUANT
order code
Effective
Please Note
flexilab code
AMINO ACIDS, QUANT, URINE (Note)
05/24/2011
This test is for internal use only.
ACETONE
order code
Effective
05/24/2011
Method
Acetest/Nitroprusside
Please Note
AAURQ
KET
flexilab code
ACETONE (SERUM) (Method, Reference Range)
Dilutions will no longer be performed or reported on posiitve results.
Reference
Ranges
ACETONE
ACMPS
order code
Effective
Please Note
Effective
05/24/2011
Method
Nephelometry
Comments
ARTHID
flexilab code
ARTHROPOD ID (Delete)
This test is being discontinued. Use the ordercode PARID to order this test.
order code
Specimen
Requirements
ACID MUCOPOLYSACCHARIDES, URINE (Note)
05/24/2011
CC1QSM
CPT4
flexilab code
This test is for internal use only.
order code
Delete
ACMPS
05/24/2011
ARTHID
Effective
Negative
CC1QSM
flexilab code
COMPLEMENT C1Q (New)
86160
1 mL serum (SST tube). Patient should be fasting. Separate serum from the cells and put in separate
plastic tube. Store and transport refrigerated.
1) Min Amt 0.5 mL. 2) Unacceptable conditions: grossly lipemic samples. 3) Stability: RT-21 days,
Refrigerated-21 days, Frozen-21 days. 4) Mayo# 8851.
Reference
Ranges
Complement C1q
12-22
mg/dL
PAML TEST CHANGE ALERT #372 page: 8
CHROMA
order code
Effective
Please Note
flexilab code
CHROMOGRANIN A (See Note)
Immediately
Effective May 16, 2011, ARUP Laboratories will change the test kIt for the assay, Chromogranin A. Due to
differences in the analytical components of the current and replacement kits, test results obtained with
each cannot be used interchangeably. To facilitate a comparison and rebaselining of individual patient
results, specimens received for Chromogranin A testing will be analyzed with both the current and
replacement tests beginning on March 16, 2011, and the results of both tests will be reported.
Chromogranin A concentrations as determined by the current assay will be reported until May 15, 2011, or
until the supply of current kits is exhausted.
COBABA
order code
Effective
05/24/2011
Method
ICP/MS
CPT4
CHROMA
COBABA
flexilab code
COBALT, BLOOD (New)
83018
Specimen
Requirements
7 mL K2EDTA or NaEDTA whole blood (royal blue top tube). Store & transport in original collection tube at
room temperature. Diet, medication, and nutritional supplements may introduce interfering substances.
Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, nonessential
over-the-counter medications (upon the advice of their physician).
Comments
1) Min Amt: 0.5 mL. 2) Unacceptable conditions: heparin anticoagulants. 3) Stability: If the sample is
drawn and stored in the appropriate container, the trace element values do not change with time. 4) ARUP
# 0099231.
Reference
Ranges
Cobalt, Blood
COBAUA
order code
Effective
05/24/2011
Method
ICP/MS
CPT4
Specimen
Requirements
Comments
0.5-3.9
COBAUA
flexilab code
ug/L
COBALT, URINE (New)
83018
10 mL aliquot from a 24-hour or random urine collection in a clean, leak- proof plastic urine container.
Refrigerate during collection. Submit 10 mL from a well-mixed collection into two trace element-free
transport tubes. Store and transport refrigerated. Diet, medication, and nutritional supplements may
introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements,
vitamins, minerals, nonessential over-the-counter medications (upon the advice of their physician).
Record total volume and collection time on tube & request form.
1) Min Amt: 5 mL. 2) Unacceptable conditions: urine collected within 48 hrs after administration of a
gadolinium (Gd) containing contrast media (may occur with MRI studies). Acid preserved urine. 3)
Stability: RT-1 week, Refrigerated-2 weeks, Frozen-1 year. 4) ARUP# 0025032.
Reference
Ranges
Hours
hr
PAML TEST CHANGE ALERT #372 page: 9
Collected
Total Volume
Creatinine, Ur
Creatinine, Ur
M 3-8 yrs
9-12 yrs
13-17 yrs
18-50 yrs
51-80 yrs
81 yrs +
F 3-8 yrs
9-12 yrs
13-17 yrs
18-50 yrs
51-80 yrs
81 yrs +
Cobalt, Urine
Cobalt, Urine
Cobalt, Urine
CORUFA
CORUFA
order code
flexilab code
Effective
140-700
300-1300
500-2300
1000-2500
800-2100
600-2000
140-700
300-1300
400-1600
700-1600
500-1400
400-1300
0.1-2.0
0.1-2.0
No reference interval
mL
mg/dL
mg/d
ug/L
ug/d
ug/gCR
T
CORTISOL/CORTISONE URINE FREE (Reference
Range)
Immediately
Reference
Ranges
Hours
Collected
Total Volume
Creatinine,
Urine
Creatinine,
Urine
Cortisol,
Urine, Free
Cortisol
Urine, Free
Cortisol,
Urine, Free
hr
mL
mg/dL
M 3-8 yrs
9-12 yrs
13-17 yrs
18-50 yrs
51-80 yrs
81 yrs +
F 3-8 yrs
9-12 yrs
13-17 yrs
18-50 yrs
51-80 yrs
81 yrs +
F Prepubertal
18 yrs +
Pregnancy
M Prepubertal
18 yrs +
140-700
300-1300
500-2300
1000-2500
800-2100
600-2000
140-700
300-1300
400-1600
700-1600
500-1400
400-1300
LT 25
LT 45
LT 59
LT 25
LT 32
mg/d
ug/gCR
ug/L
M 3-8 yrs
9-12 yrs
LT 18
LT 37
ug/d
PAML TEST CHANGE ALERT #372 page: 10
13-17 yrs
18 yrs +
F 3-8 yrs
9-12 yrs
13-17 yrs
18 yrs +
Cortisone,
Urine Free
Cortisone,
Urine, Free
Cortisone,
Urine, Free
Cortisol/
Cortisone
Ratio
ug/L
ug/d
M 0-11 yrs
12 yrs +
F 0-11 yrs
12 yrs +
CPPCR
order code
flexilab code
Delete
Comments
(Delete)
CFL
flexilab code
CULTURE, BODY FLUID, REFLEX (Volumes)
20 mL spinal fluid, peritoneal fluid, synovial fluid, etc, collected in a sterile tube or container. CSF should
be transported immediately at RT. Store and transport at room temperature.
1) Min Amt: 3 mL. 2) If an anticoagulant is needed-SPS is the choice. 3) PSHMC-Microbiology
Department.
order code
Please Note
CHLAMYDOPHILA PNEUMONIAE DNA QUAL
Immediately
GLUTAMINE
Effective
Ratio
This test is being discontinued.
order code
Specimen
Requirements
To be determined
0.15-0.50
To be determined
0.15-0.50
Ratios to creatinine may be useful
for eveluation when the urine
collection is random, other than 24
hours, or the urine volume is less
than 400 mL/24 hours.
The reaio of the concentrations of
cortisol to cortisone will not be
evaluated if the cortisol
concentration is less than 5 ug/L.
05/16/2011
CULT.FLD
Effective
56
60
18
37
56
45
ug/gCR
CPPCR
Effective
LT
LT
LT
LT
LT
LT
GLUTSF
flexilab code
GLUTAMINES, CSF (Note)
05/24/2011
This test will be available for internal use only.
PAML TEST CHANGE ALERT #372 page: 11
HAMAF
order code
Effective
05/24/2011
Method
ELISA
CPT4
83520
Specimen
Requirements
Comments
Compliance(RU
O)
HAMAF
flexilab code
HUMAN ANTI-MOUSE AB (HAMA) (New)
1 mL frozen serum (SST tube). Separte serum from the cells and put in separate plastic tube. Store and
transport frozen.
1) Min Amt: 0.5 mL. 2) Stability: RT-unacceptable, Refrigerated-2 days, Frozen-1 month. 3) FOCUS#
41882.
This test was performed using a kit labeled "For Research Use Only" by the kit manufacturer. The kit's
performance characteristics have been established and validated by Focus Diagnostics for in-vitro
diagnostic use.
Reference
Ranges
Human AntiMouse Ab
(HAMA)
HBSAG.NEUT
order code
Effective
Delete
Normal level
Increased level
NHBSAG
flexilab code
ng/mL
HBSAG BY NEUTRALIZATION (Delete)
05/24/2011
This test is being discontinued.
HBYGA
order code
HBYGA
flexilab code
Effective
05/24/2011
Method
PCR/Nucleic Acid Sequencing
CPT4
0-188
GT 188
This assay was performed using a
kit labeled "For Research Use Only"
by the kit manufacturer. The kit's
performance characteristics have
been established and validated by
Focus Diagnostics for in-vitro
diagnostic use.
HEPATITIS B VIRUS GENOTYPE (New)
83890, 83898, 83904 x 2, 83909, 83912
Specimen
Requirements
2 mL frozen serum (SST tube). Separate serum from cells within 2 hours of collection and put in separate
plastic tube and freeze. CRITICAL FROZEN. Separate samples must be submitted when multiple tests are
ordered. Store and transport frozen. Ship 650.
Comments
1) Min Amt: 0.5 mL. 2) Other acceptable specimens: PPT tube or EDTA or ACD A or B plasma (lavender
or yellow top tube). 3) Unacceptable conditions: non-frozen or heparinized specimens. Specimens
exposed to repeat freeze/ thaw cycles. 4) Stability: RT-unacceptable, Refrigerated-unacceptable, Frozen-4
months. 5) ARUP# 2001567.
Compliance(LD
TB)
PAML/SHMC
This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S.
Food and Drug Administration (FDA) has not approved or cleared this test. However, FDA approval or
clearance is currently not required for clinical use of this test. The results are not intended to be used as
the sole means for clinical diagnosis or patient management decisions.
PAML TEST CHANGE ALERT #372 page: 12
Reference
Ranges
Hepatitis B
Genotype
HBV Surface
Ag Mutations
HBV RT
Polymerase
Mutations
HCRIBA
order code
Effective
Please Note
Not detected
Not detected
This test was developed and its
performance characteristics
determined by ARUP Lab. The U.S.
Food and Drug Administration has
not approved or cleared this
test; however, FDA clearance or
approval is not currently required
for clinical use. The results are
not intended to be used as the sole
means for clinical diagnosis or
patient management decisions.
HCRIBA
flexilab code
Immediately
This test is back on line.
HEXALM
HEXALM
order code
flexilab code
Effective
HEPATITIS C AB BY RIBA (Please Note)
HEXOSAMINIDASE A & TOTAL, LEUKOCYTE
(Reference Range Units)
Immediately
Reference
Ranges
Hexosaminidase
A & Total,WBC
Percent A
MML Comment
16.4-36.2
63-75
HGH
HGH
order code
flexilab code
Effective
Please Note
U/gProt
%
HGH (HUMAN GROWTH HORMONE) (Reference
Range )
Immediately
The following associated tests will also be reporting the patient results and reference range to two decimal
places: HGH.S1/GH1, HGH.S2/GH2, HGH.S3/GH3, HGH.S4/HGH4, HGH.S5/HGH5, HGH.S6/HGH6,
HGH.S7/HGH7 and HGH.S8/HGHP8.
Reference
Ranges
HGH
0.00-10.00
ng/mL
PAML TEST CHANGE ALERT #372 page: 13
HTLYWB
order code
Effective
Delete
Effective
05/24/2011
Method
MAFD
CPT4
83520
Compliance(LD
TB)
PAML/SHMC
HTLV-I/II ANTIBODY, WESTERN BLOT( Delete)
This test is being discontinued.
order code
Comments
flexilab code
Immediately
IL1BA
Specimen
Requirements
HTLYWB
IL1BA
flexilab code
INTERLEUKIN 1 BETA BY MAFD (New)
1 mL frozen serum (SST tube). Separate serum from the cells ASAP and put in separate plastic tube and
freeze. CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.
Store and transport frozen.
1) Min Amt: 0.3 mL. 2) Other acceptable specimens: lithium heparin plasma (green top tube). 3)
Unacceptable conditions: heat-inactivated, refrigerated or contaminated specimens. 4) Stability: RT-30
minutes, Refrigerated-unacceptable, Frozen-1 year. 5) ARUP# 0051536.
This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S.
Food and Drug Administration (FDA) has not approved or cleared this test. However, FDA approval or
clearance is currently not required for clinical use of this test. The results are not intended to be used as
the sole means for clinical diagnosis or patient management decisions.
Reference
Ranges
Interleukin 1
beta by MAFD
IMI
IMDES
order code
Effective
0-36
This test was developed and its
performance characteristics
determined by ARUP Laboratories.
The U. S. Food & Drug
Administration has not approved or
cleared this test; however, FDA
clearance or approval is not
currently required for clinical
use. The results are not intended
to be used as the sole means for
clinical diagnosis or patient
management decisions.
flexilab code
pg/mL
IMIPRAMINE & METABOLITE (Reference Range)
05/24/2011
Reference
Ranges
Imipramine
No reference range established for
ng/mL
parent drug. See total for reference
range which takes into account all
metabolites.
PAML TEST CHANGE ALERT #372 page: 14
Desipramine
Therapeutic: 150-300
Toxic:
GT 499
Therapeutic: 150-300
Toxic:
GT 499
Total Drug
MAPRLA
order code
MAPRLA
flexilab code
Effective
05/24/2011
Method
Chemiluminescent Immunoassay
CPT4
Specimen
Requirements
Comments
ng/mL
ng/mL
MACROPROLACTIN (New)
84146 x 2
1 mL frozen serum (SST tube). Allow serum specimen to clot completely at room temperature before
centrifuging. Separate serum from cells and put in separate plastic tube and freeze. Store and transport
frozen.
1) Min Amt: 0.5 mL. 2) Other acceptable specimens: PST tube or sodium or lithium heparin plasma (green
top tube). 3) Unacceptable conditions: EDTA plasma. 4) Stability: RT-8 hours, Refrigerated-2 days,
Frozen-3 months. 5) ARUP# 0020765.
Reference
Ranges
Prolactin
Prolactin,
Monomeric
M 1-9 yrs
10 yrs +
F 1-9 yrs
10 yrs +
M 1-9 yrs
10 yrs +
F 1-9 yrs
10 yrs +
Prolactin %,
Monomeric
METABOLIC.SC METSUR
R
order code
Effective
Please Note
METABOLIC SCREEN (Note)
This test is for internal use only.
order code
flexilab code
Comments
ng/mL
05/24/2011
METMB
Specimen
Requirements
ng/mL
flexilab code
METMB
Effective
2.1-17.7
2.1-17.7
2.1-17.7
2.8-26.0
2.1-13.3
2.1-13.3
2.1-13.3
2.8-19.5
GT 50%
METHADONE & META, SERUM (Specimen
Requirements)
Immediately
4 mL serum (red top tube). Separate serum from cells ASAP & put in separate plastic tube. Store and
transport refrigerated.
1) Min Amt: 2 mL. 2) Other acceptable specimens: potassium oxalate/ sodium fluoride plasma, sodium
heparin plasma, EDTA or K2EDTA whole blood (grey, green, lavender or pink top tube). 3) Unacceptable
conditions: SST, plasma or sodium citrate whole blood (light blue top tube) and repeat freeze/thaw cycles.
4) Stability: RT-1 week, Refrigerated-2 weeks, Frozen- 3 years. 5) ARUP# 0090699.
PAML TEST CHANGE ALERT #372 page: 15
MPQTUA
order code
Effective
05/24/2011
Method
Spectrophotometry
CPT4
Specimen
Requirements
Comments
MPQTUA
flexilab code
MUCOPOLYSACCHARIDES, QUANT, URINE (New)
83864
20 mL frozen urine. Collect urine in a leakproof plastic urine container. Prefer morning void. Aliquot 20 mL
into a leakproof plastic urine container and freeze immediately. CRITCIAL FROZEN. Store and transport
frozen. If multiple tests are ordered, separate samples must be submitted. Complete a patient history form
for mucopolysaccharidosis (mps) testing available at www.aruplab.com for test code 0081357, and send it
with specimen.
1) Min Amt: 10 mL. 2) Unaccceptable conditions: contaminated specimens and specimens containing
preservatives. Avoid repeated freeze/thaw cycles. 3) Stability: RT-unacceptable, Refrigeratedunacceptable, Frozen-1 month. 4) ARUP# 0081357.
Reference
Ranges
Mucopolysaccharides,
Urine
MYEGF
order code
Effective
05/24/2011
Method
IFA
CPT4
Specimen
Requirements
Comments
Compliance(IU
O)
0-5 mo
6-11 mo
1-2 yrs
3-6 yrs
7-13 yrs
14 yrs+
MYEGF
flexilab code
14.6-47.8 mg/mmol CRT
3.7-35.5
5.4-30.8
5.2-30.8
2.4-10.2
0.0-7.1
MYELIN IGG ANTIBODY (New)
86255
1 mL serum (SST tube). Separate serum from cells and put in separate plastic tube. Store and transport
refrigerated.
1) Min Amt: 0.1 mL 2) Stability: RT-1 week, Refrigerated-2 weeks, Frozen- 1 month. 3) Focus# 20545.
This test was performed using a kit that has not been cleared or approved by the FDA. The analytical
performance characteristics of this test have been determined by Focus Diagnostics. This test should not
be used for diagnosis without confirmation by other medically established means.
Reference
Ranges
Myelin IgG Ab
Negative
This test was performed using a kit
that has not been cleared or
approved by the FDA. The analytical
performance characteristics of this
test have been determined by Focus
Diagnostics. This test should not
be used for diagnosis without
confirmation by other medically
established means.
PAML TEST CHANGE ALERT #372 page: 16
NMOCM
NMOCM
order code
flexilab code
Effective
Delete
This test is being discontinued.
order code
Delete
NMOIG
This test is being discontinued.
order code
OBGA
05/24/2011
Method
Qualitative Colorimetry
Comments
OCCULT BLOOD, GASTRIC (New)
flexilab code
Effective
Specimen
Requirements
NEUROMYELITIS OPTICA NMO AB IGG (Delete)
flexilab code
Immediately
OBGA
CPT4
(Delete)
Immediately
NMOIG
Effective
NEUROMYELITIS OPTICA AUTOAB IGG CSF
82271, 83986
1 mL gastric fluid in a leakproof plastic container. Limit ingestion of raw fruits and vegetables and
incompletely cooked meat. Store and transport refrigerated.
1) Min Amt: 1 mL. 2) Unacceptable conditions: frozen specimens, specimens in preservatives. 3) Stability:
RT-24 hours, Refrigerated-5 days, Frozen- unacceptable. 4) ARUP# 0060310.
Reference
Ranges
Occult Blood,
Gastric Fluid
Gastric Fluid
pH
ORAU
order code
Effective
Please Note
ORAU
flexilab code
ORGANIC ACIDS URINE (Note)
This test is for internal use only.
order code
Effective
05/24/2011
Method
GC/MS
Specimen
Requirements
1-7
05/24/2011
ORAURA
CPT4
Negative
ORAURA
flexilab code
ORGANIC ACIDS, URINE (New)
83918
10 mL frozen urine, random collection. Collect random urine specimen in a leakproof plastic urine
container. Aliquot 10 mL into a leakproof plastic tube and freeze ASAP. Store and transport frozen.
PAML TEST CHANGE ALERT #372 page: 17
CRITICAL FROZEN. Separate samples must be submitted when multiple tests are ordered. Avoid dilute
urine. Complete a patient history for biochemical genetic testing available at www.aruplab.com test #
0098389 and send with sample.
Comments
1) Min Amt: 3 mL. 2) Stability: RT-unacceptable, Refrigerated-unacceptable, Frozen-1 month. 3) ARUP#
0098389.
Reference
Ranges
Creatinine,
Urine
Organic Acids,
Urine Interp
Lactic Acid,
Urine
Pyruvic Acid,
Urine
Succinic Acid,
Urine
Fumaric Acid,
Urine
2-Ketoglutaric
Acid, Urine
Methylmalonic
Acid, Urine
3-OH-Butyric
Acid, Urine
Acetoacetic
Acid, Urine
2-Keto-3methylvaleric
Acid, Urine
2-Ketoisocaproic Acid,
Urine
2-Ketoisovaleric Acid,
Urine
Ethylmalonic
Acid, Urine
Adipic Acid,
Urine
Suberic Acid,
Urine
Sebacic Acid,
Urine
mg/dL
Normal
0-1 mo
1 mo-12 yr
12 yrs +
0-1 mo
1 mo-12 yrs
12 yrs +
0-1 mo
1 mo-12 yrs
12 yrs +
0-1 mo
1 mo-12 yrs
12 yrs +
0-1 mo
1 mo-12 yrs
12 yrs +
0-1 mo
1 mo-12 yrs
12 yrs +
0-1 mo
1 mo-12 yrs
12 yrs +
0-1 mo
1 mo-12 yrs
12 yrs +
0-1 mo
1 mo-12 yrs
12 yrs +
0-1 mo
1 mo-12 yrs
12 yrs +
0-1 mo
1 mo-12 yrs
12 yrs +
0-1 mo
1 mo-12 yrs
12 yrs +
0-1 mo
1 mo-12 yrs
12 yrs +
0-1 mo
1 mo-12 yrs
12 yrs +
0-1 mo
1 mo-12 yrs
12 yrs +
0-160
0-150
0-50
0-50
0-30
0-15
0-125
0-80
0-20
0-14
0-10
0-4
0-525
0-120
0-75
0-5
0-5
0-5
0-10
0-4
0-4
0-4
0-4
0-4
0-10
0-10
0-10
0-5
0-4
0-4
0-5
0-4
0-4
0-10
0-15
0-4
0-35
0-35
0-35
0-10
0-10
0-3
0-10
0-3
0-3
mmol/molCRT
mmol/molCRT
mmol/molCRT
mmol/molCRT
mmol/molCRT
mmol/molCRT
mmol/molCRT
mmol/molCRT
mmol/molCRT
mmol/molCRT
mmol/molCRT
mmol/molCRT
mmol/molCRT
mmol/molCRT
mmol/molCRT
PAML TEST CHANGE ALERT #372 page: 18
4-OH-phenylactic Acid,
Urine
4-OH-phenyllactic Acid,
Urine
4-OH-phenylpyruvic Acid,
Urine
Succinylacetone,
Urine
0-1 mo
1 mo-12 yrs
12 yrs +
0-1 mo
1 mo-12 yrs
12 yrs +
0-1 mo
1 mo-12 yrs
12 yrs +
0-1 mo
1 mo-12 yrs
12 yrs
PARID
PARID
order code
flexilab code
Effective
Specimen
Requirements
Comments
PARASITE ID (MACROSCOPIC) (Specimen
Requirements)
PTHINT
flexilab code
PTH INTACT NO CALCIUM (Critical Frozen)
2 mL frozen EDTA plasma (lavender top tube). Separate plasma from cells promptly and freeze in
separate plastic tube. Store and transport frozen. THIS ASSAY IS FOR THE WHOLE MOLECULE
(INTACT) PTH AND NO CALCIUM IS REPORTED. This is a CRITICAL FROZEN.
Effective
05/24/2011
Method
Semi-Quant ELISA
Comments
mmol/molCRT
Immediately
order code
Specimen
Requirements
mmol/molCRT
1) Unacceptable conditions: frozen or dried specimens. Limitations: Worms and arthropods will be
identified if they are human parasites. Environmental, non-parasitic organisms will be generically identified
as "Not a human parasite". 3) Stability: RT-stable, Refrigerated-stable, Frozen-unacceptable. 4) PSHMCMicrobiology Departement.
RNAPAA
CPT4
mmol/molCRT
Suspected parasites may be collected & submitted in a sterile container with a tight fitting lid. Worms
should be submitted in formalin or Unifix to prevent dessication. For scabies collection, please refer to
PAML web directory or call Microbiology Department .
order code
Specimen
Requirements
mmol/molCRT
05/24/2011
PTHINT
Effective
0-150
0-100
0-25
0-20
0-4
0-4
0-20
0-2
0-2
0-0
0-0
0-0
RNAPAA
flexilab code
RNA POLYMERASE III AB, IGG (New)
83516
1 mL serum (SST tube). Separate serum from cells ASAP and put in separate plastic tube. Store and
transport refrigerated.
1) Min Amt: 0.2 mL. 2) Stability: RT-2 days, Refrigerated-2 weeks, Frozen- 1 year. 3) ARUP# 2001601.
Reference
Ranges
RNA Polymerase
3 Ab, IgG
0-19
20-39
40-80
81 or more
Negative
Weak Positive
Moderate Positive
Strong Positive
Units
PAML TEST CHANGE ALERT #372 page: 19
SS.LAP
order code
Effective
Specimen
Requirements
Comments
1) Unacceptable conditions: EDTA tube only. Slides made from EDTA tube (lavender top tube) or PST
tube (lime green tube). 2) PSHMC-Hematology Department.
Effective
05/24/2011
Method
ELISA
CPT4
83516
Compliance(IU
O)
flexilab code
TESTOSTERONE WEAKLY BINDING (Delete)
This test is being discontinued.
order code
Comments
TESTFW
Immediately
TYSABF
Specimen
Requirements
LEUK ALK PHOS STAIN (Specimen Requirements)
3-5 mL heparin whole blood (green top tube) & 3 well-made, non-fixed, non- EDTA blood smears. An
additional EDTA tube or CBC result optional but preferred. Protect slides from light and store and transport
at room temperature. Indicate source.
order code
Delete
flexilab code
05/24/2011
TESTFW
Effective
LAP
TYSABF
flexilab code
TYSABRI ANTIBODIES (New)
1 mL serum (SST tube). Separate serum from cells and put in separate plastic tube. Store and transport
refrigerated.
1) Min Amt: 0.5 mL. 2) Stability: RT-unacceptable, Refrigerated-2 weeks, Frozen-1 month. 3) Focus#
20443.
This assay was developed and its performance characteristics have been determined by Focus
Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has
determined that such clearance or approval is not necessary. Performance characteristics refer to the
analytical performance of the test.
Reference
Ranges
Tysabri Abs
Negative
This assay was developed and its
performance characteristics have
been determined by Focus
Diagnostics. It has not been
cleared or approved by the U.S.
Food and Drug Administration. The
FDA has determined that such
clearance or approval is not
necessary. Performance
characteristics refer to the
analytical performance of the test.
PAML TEST CHANGE ALERT #372 page: 20
VAN
VAN
order code
Effective
Comments
flexilab code
05/24/2011
1) Min Amt: 0.2 mL. 2) Other acceptable specimens: SST, serum & sodium or lithium heparin. 3)
Unacceptable conditions: EDTA plasma or severe hemolysis. 4) Stability: RT-1 week, Refrigerated-1
week, Frozen-2 weeks. 5) PSHMC-Chemistry Department.
VAN.PK
order code
Effective
Comments
flexilab code
VANCTR
flexilab code
1) Min Amt: 0.3 mL. 2) Other acceptable specimens: SST, serum, sodium or lithium heparin. 3)
Unacceptable conditions: EDTA plasma or severe hemolysis. 4) Stability: RT-1 week, Refrigerated-2
weeks, Frozen-2 weeks. 5) PSHMC-Chemistry Department.
VANIN
order code
flexilab code
Comments
order code
flexilab code
C.TRACHOMATIS/N.GONORRHOEAE SDA/PAP
(CPT Coding)
Immediately
87491, 87591
VITB5A
order code
Effective
05/24/2011
Method
HPLC
CPT4
84591
Specimen
Requirements
Requriements)
1) Min Amt: 0.2 mL. 2) Other acceptabe specimens: SST serum, sodium or lithium heparin. 3)
Unacceptable conditions: EDTA plasma or severe hemolysis. 4) Stability: RT-1 week, Refrigerated-1
week, Frozen-2 weeks. 5) PSHMC-Chemistry Department.
VIPCG
CPT4
VANCOMYCIN (PEAK & TROUGH) (Specimen
05/24/2011
VIPCG
Effective
VANCOMYCIN, TROUGH (Specimen Requirements)
05/24/2011
VAN2
Effective
VANCOMYCIN, PEAK (Specimen Requirements)
1) Min Amt: 0.2 mL. 2) Other acceptable specimens: SST serum & sodium or lithium heparin. 3)
Unacceptable conditions: EDTA plasma or severe hemolysis. 4) Stability: RT-1 week, Refrigerated-1
week, Frozen-2 weeks. 5) PSHMC-Chemistry Department.
order code
Comments
VANCPK
05/24/2011
VAN.TR
Effective
VANCOMYCIN (Specimen Requirements)
VITB5A
flexilab code
VITAMIN B5 (PANTOTHENIC ACID) (New)
4 mL frozen EDTA plasma (lavender top tube). Separate plasma from cells ASAP and put in separate
plastic tube and freeze. Protect from light during collection, storage & transport. CRITICAL FROZEN.
PAML TEST CHANGE ALERT #372 page: 21
Separate specimens must be submitted when multiple tests are ordered. Store and transport frozen.
Comments
1) Min Amt: 2 mL. 2) Unacceptable conditions: grossly hemolyzed or lipemic specimens. Thawed samples
and samples not protected from light. 3) Stability: RT-unacceptable, Refrigerated-unacceptable, Frozen-1
month. 4) ARUP# 2003186-then sent to Cambridge Biomedical Research Group, MA.
Compliance(LD
TB)
PAML/SHMC
The performance characteristics of this assay were validated by Cambridge Biomedical, Inc. The US FDA
has not approved or cleared this test. The results of this assay can be used for clinical diagnosis without
FDA approval. Cambridge Biomedical Inc. is a CLIA certified, CAP accredited laboratory for performing
high complexity assays such as this one.
Reference
Ranges
Pantothenic
Acid (B-5)
1 yr or less
GT 1-10 yrs
GT 10 yrs
VITB7A
order code
Effective
05/24/2011
Method
Bioassay
CPT4
VITB7A
flexilab code
LT 200
Low
200-1196 Normal
GT 1196
High
LT 200
Low
200-1241 Normal
GT 1241
High
LT 200
Low
200-1800 Normal
GT 1800
High
The performance characteristics of
this test was validated by
Cambridge Biomedical Inc. The U.S.
FDA has not approved or cleared
this test. The results of this
assay can be used for clinical
diagnosis without FDA approval.
Cambridge Biomedical Inc. is a
CLIA certified, CAP accredited
laboratory for performing high
complexity assay such as this one.
ng/mL
VITAMIN B7 (BIOTIN) (New)
84591
Specimen
Requirements
2 mL frozen serum (SST tube). Allow to clot for 30 minutes before separation. Separate serum from cells
and put in separate amber plastic tube and freeze immediately. Store and transport frozen. CRITICAL
FROZEN. Separate samples must be sent when multiple tests are ordered. Protect from light.
Comments
1) Min Amt: 1 mL. 2) Unacceptable conditions: grossly hemolyzed samples. Thawed samples or samples
not protected from light. 3) Other acceptable specimens: serum (red top tube). 4) Stability: RTunacceptable, Refrigerated-unacceptable, Frozen-1 month. 5) ARUP# 2003184-then sent to Cambridge
Biomedical Research Group.
Compliance(LD
TB)
PAML/SHMC
The performance characteristics of this assay were validated by Cambridge Biomedical, Inc. The US FDA
has not approved or cleared this test. The results of this assay can be used for clinical diagnosis without
FDA approval. Cambridge Biomedical Inc. is a CLIA certified, CAP accredited laboratory for performing
high complexity assays such as this one.
Reference
Ranges
Biotin
(Vitamin B7)
LT 12 yrs
12 yrs+
57.0-2460.2
221.0-3004.0
The performance characteristics of
pg/mL
PAML TEST CHANGE ALERT #372 page: 22
this test were validated by
Cambridge Biomedical Inc. The U.S.
FDA has not approved or cleared
this test. The results of this
assay can be used for clinical
diagnosis without FDA approval.
Cambridge Biomedical Inc, is a CLIA
accredited laboratory for
performing high complexity assays
such as this one.
VORIF
order code
Effective
05/24/2011
Method
HPLC
CPT4
80299
Specimen
Requirements
Comments
VORIF
flexilab code
VORICONAZOLE LEVEL, HPLC (New)
2 mL frozen serum (plain red top tube). Specimens collected just before or within 15 min of next dose are
the Trough levels. Specimens obtained within 15-30 minutes after the end of I.V. infusion or 45-60 minutes
after an IM injection or 90 minutes after oral intake represent the Peak level. Separate serum from cells
and put in separate sterile plastic tube and freeze. CRITICAL FROZEN. Separate specimens must be
submitted when multiple tests are ordered. Store and transport frozen.
1) Min Amt: 1 mL. 2) Other acceptable specimens: heparin or EDTA plasma (green or lavender top tube)
or CSF. 3) Unacceptable conditions: non-frozen samples. Specimens collected in SST; sterile tube
preferred. 4) Stability: RT-unacceptable, Refrigerated-unacceptable, Frozen-2 weeks. 5) Focus# 51929.
Reference
Ranges
Voriconazole
Level, HPLC
Population Pharmacokinetic
Parameters
Day 1, 400 mg Oral Q12
Days 2-10, 200 mg Oral Q12
Day 1, 6 mg/kg IV Q12
Days 2-10, 3 mg/kg IV Q12
mcg/mL
2.3
2.1
4.7
3.1
PAML Web Test Directory
PAML TEST CHANGE ALERT #372 page: 23