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DEPAKOTE SAVINGS PROGRAM Pay as little as 5 $ BILL PRIMARY INSURANCE FIRST INSURED PATIENTS ONLY RxBIN: 601341 RxPCN: OHCP OH9001121 RxGrp: RxID: 436100100838 Suf: 01 per month* *Up to $75 off for eligible insured patients. See brochure for Important Safety Information, including warnings for risk of liver problems, pancreas problems, and birth defects. See full Prescribing Information in pocket. Use this card every time you fill your Depakote prescription. Start Saving Today.* * See eligibility restrictions below. STEP 1 STEP 2 ✓ Take this printout with your prescription for Depakote, Depakote ER, or Depakote Sprinkle Capsules to your pharmacist and start saving immediately! Present this printed Co-Pay Card every time you fill a Depakote, Depakote ER, or Depakote Sprinkle Capsules prescription for instant savings. This card can be used up to 2 times per month. You pay the first $5 of your co-payment on qualified prescriptions, and the discount covers up to the next $75 off of your remaining co-pay expenses. The card is valid at mail-order pharmacies, but they may have different requirements. If needed, you can find a rebate form on Depakote.com. When filling a prescription for Depakote, Depakote ER, or Depakote Sprinkle Capsules, make sure your pills look like those shown below. If not, call your doctor or talk to your pharmacist. Depakote 125 mg ✓ ✓ Depakote 250 mg Depakote 500 mg Depakote ER 250 mg Depakote ER 500 mg Depakote Sprinkle Capsules 125 mg Tablets and Capsule Shown Are Not Actual Size Inform your pharmacist of your preference for the Depakote brand. Check the label on your prescription bottle to be sure it says Depakote, Depakote ER, or Depakote Sprinkle Capsules. Patient Instructions: Present this printable version of the Depakote, Depakote ER, or Depakote Sprinkle Capsules Co-Pay Card along with your insurance card when presenting your prescription in order to receive discounts. You pay the first $5 of your co-payment on qualified prescriptions and the discount covers up to the next $75 off of your remaining co-pay expenses. This printout is valid for up to 2 uses per month. This is also valid at mail-order pharmacies, yet they may have different requirements. Please contact your mail-order pharmacist for redemption instructions. Pharmacist Instructions: Please submit the co-pay authorized by the patient’s primary insurance as a secondary transaction to OPUS Health. If you have questions, please call OPUS Health at: 1-800-364-4767. This offer may be changed or discontinued without notice. *Eligibility Restrictions: This downloadable discount is the property of AbbVie Inc. and must be surrendered upon demand. This is not valid for persons eligible for reimbursement of this product, in whole or in part, under Medicare, Medicaid or similar federal or state programs or in Massachusetts. Offer void where prohibited by law. Please read Uses and Important Safety Information, including risks of liver problems, pancreas problems, and birth defects on the next page. Full Prescribing Information available at http://www.Depakote.com/prescribing-information What is Depakote used for? Other serious side effects from taking Depakote: Depakote comes in different dosage forms. Depakote® (divalproex sodium) Tablets for Oral use and Depakote® ER (divalproex sodium) Tablet, Extended Release for Oral use are prescription medications used: • To treat acute manic episodes associated with bipolar disorder • Alone or with other medications to treat: – Complex partial seizures in adults and children 10 years of age and older – Simple and complex absence seizures, with or without other seizure types • Low blood platelet counts • High blood ammonia levels • Hypothermia (body temperature less than 95º F) • Allergic reactions • Extreme drowsiness in some elderly patients. Causing less than normal eating or drinking • To prevent migraine headaches Depakote® Sprinkle Capsules (divalproex sodium coated particles in capsules), for oral use is a prescription medicine used alone or with other medicines to treat: • Complex partial seizures in adults and children 10 years of age and older • Simple and complex absence seizures, with or without other seizure types Important Safety Information The most important information about Depakote: Do not stop taking Depakote without first talking to your doctor. Stopping Depakote suddenly can cause serious problems. Depakote can cause SERIOUS SIDE EFFECTS, including: • Serious liver damage that can cause death, especially in children younger than 2 years old. The risk of getting serious liver damage is more likely within the first 6 months of treatment. Liver damage may continue despite stopping the drug. Call your doctor right away if you develop any of these symptoms: nausea or vomiting that doesn’t go away, loss of appetite, pain on the right side of your stomach, dark urine, swelling of your face, or yellowing of your skin or whites of your eyes. • Depakote may harm your unborn baby. Taking Depakote during pregnancy puts your baby at risk for serious birth defects. The most common birth defects affect the brain and spinal cord, called spina bifida or neural tube defects, and occur in 1 to 2 out of every 100 babies born to mothers who use Depakote during pregnancy. These defects can begin in the first month, before you know you are pregnant. Other birth defects can also happen. If you take Depakote while you are pregnant, your child is at risk for having a lower IQ. Women who are pregnant must not take Depakote to prevent migraine headaches. All women of childbearing age should talk to their doctor about using other treatments instead of Depakote. There may be other medicines to treat your condition that have a lower chance of causing birth defects and decreased IQ in your child. If you use Depakote, use effective birth control. Tell your healthcare provider right away if you become pregnant while taking Depakote. Taking folic acid supplements before getting pregnant and during early pregnancy can lower the chance of having a baby with neural tube defects. • Inflammation of your pancreas that can cause death. Call your doctor right away if you develop severe stomach pain that you may also feel in your back, or nausea or vomiting that does not go away. • Depakote may cause suicidal thoughts and actions in a very small number of people, about 1 in 500. Be alert for any sudden changes in mood, behaviors, thoughts or feelings. Call your doctor right away if you have any of these symptoms, especially if they are new or worsen: thoughts of suicide or dying; attempting suicide; new or worse depression, anxiety or irritability; feeling agitated or restless, angry, aggressive, or violent; panic attacks; trouble sleeping; acting on dangerous impulses; or extreme increase in talking or activity. DO NOT TAKE Depakote if you: • Have liver problems • Have or think you have a genetic liver problem caused by a mitochondrial disorder (e.g., Alpers-Huttenlocher syndrome) • Are allergic to the ingredients • Have a genetic condition called urea cycle disorder, causing too much ammonia to build up in your body • DO NOT TAKE Depakote for the prevention of migraine headaches if you are pregnant BEFORE starting Depakote, tell your healthcare provider if you: • Have liver disease • Have a genetic liver problem caused by a mitochondrial disorder (e.g., Alpers-Huttenlocher syndrome) • Are pregnant, planning to become pregnant, or breastfeeding • Drink alcohol • Have depression, mood problems, or suicidal thoughts or behavior • Have a colostomy, ileostomy, or gastrointestinal disorder • Have any other medical condition • Take any medicines, including those with and without a prescription, vitamins, and herbal supplements and medicines ©2013 AbbVie Inc. North Chicago, IL 60064 809685-836411 June 2013 Tell your healthcare provider right away if you develop: • Red or purple spots on your skin • Bruising • Bleeding from your mouth, teeth, or nose • Abnormal drowsiness, a feeling of being more tired or drowsy than usual • Vomiting • Confusion, difficulty thinking, or difficulty staying awake or waking up • An inability to eat or drink as you normally do, a loss of appetite or not wanting to eat or drink as you normally do • Call your doctor immediately if you become pregnant or think you are pregnant. If you want to become pregnant, let your doctor know before you begin trying • Tell your doctor if you notice the shell of the Depakote tablet or capsule in your stool Or if you develop signs of an allergic reaction including the following: 1. Fever 5. Sores in mouth 2. Skin rash 6. Swelling of lymph nodes, face, 3. Hives eyes, lips, tongue, or throat 4. Blisters 7. Trouble swallowing or breathing Some common side effects of Depakote: • Nausea • Headache • Sleepiness • Tremor • Dizziness • Weakness • Hair loss • Diarrhea • Vomiting • Weight gain • Blurry vision • Loss of appetite • Increased appetite • Coordination problems • Walking problems • Stomach pain • Double vision References: 1. Depakote [package insert]. 2. Depakote ER [package insert]. 3. Depakote Sprinkle Capsules [package insert]. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088. If you cannot afford your medication, contact www.pparx.org or call the toll-free phone number (1-888-4PPA-NOW) for assistance.