New treatment for stroke set to increase chances of recovery

MEDIA RELEASE
Embargoed until 12:01pm, Wednesday 29 May, (GMT, London time)
#treatstroke
New treatment for stroke set to increase
chances of recovery
Findings from largest global study of its kind
to change treatment of intracerebral haemorrhage globally
A landmark study has revealed a new way to treat intracerebral haemorrhage which stands to help
millions of people worldwide.
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The George Institute for Global Health study found that intensive blood pressure lowering in patients
with intracerebral haemorrhage, the most serious type of stroke, reduced the risk of major disability
and improved chances of recovery by as much as 20 per cent.
The study, which involved more than 2800 patients from 140 hospitals around the world was
announced today at the European Stroke Conference in London, and published in The New England
Journal of Medicine.
Intracerebral haemorrhage, spontaneous bleeding within the brain most often due to hypertension,
affects one million people globally each year, kills 30 – 60 per cent of sufferers and leaves 50 per cent
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of survivors disabled .
Study lead and neurologist, Professor Craig Anderson of The George Institute and The University of
Sydney said the study challenges previous thought about blood pressure lowering in intracerebral
haemorrhage.
“The study findings will mean significant changes to guidelines for stroke management worldwide.
They show that early intensive blood pressure lowering, using widely available therapies, can
significantly improve the outcome of this illness.
“We hope to see hospital emergency departments around the world implement the new treatment as
soon as possible.
“By lowering blood pressure, we can slow bleeding in the brain, reduce damage and enhance
recovery.
“The study findings are tremendously exciting because they provide a safe and efficient treatment to
improve the likelihood of a recovery without serious disability - a major concern for those who have
experienced stroke.
“The only treatment option to date has been risky brain surgery, so this research is a very welcome
advance,” Professor Anderson said.
The study found patients who suffered an acute intracerebral haemorrhage and received the blood
pressure lowering treatment were better off from both a physical and psychological perspective.
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Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial (INTERACT2)
Global Burden of Disease Study 2010, The Lancet, Volume 380, Issue 9859, 15 December 2012, Pages 2053 2054
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Global Study Director, Dr Emma Heeley of The George Institute and The University of Sydney said
the findings provide new hope for stroke survivors and their families, but highlights the need to get to
hospital as quickly as possible if a stroke is suspected.
“Getting a stroke victim to an emergency department as fast as possible is vital to the success of this
treatment.
“The sooner a medical team is able to lower the patient’s blood pressure, the greater their chances of
leaving hospital with a good outcome,” Dr Heeley said.
ENDS
MEDIA ENQUIRIES
United Kingdom and Europe:
Graham Bagley
+44 7747 445843
graham.bagley@georgecentre.ox.ac.uk
All other countries:
Maya Kay
+61 410 411 983
mkay@georgeinstitute.org.au
BACKGROUND INFORMATION
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The major signs of stroke include facial weakness, arm weakness and speech or
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comprehension difficulties . Other signs include:
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For more information visit http://www.interact2.org
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INTERACT2 trial investigators per region:
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Weakness, numbness or paralysis of the face, arm or legs
Dizziness, loss of balance or an unexplained fall
Loss of vision, sudden blurring or decreased vision
A severe headache with sudden onset
Difficulty speaking
Americas: Alejandro Rabinstein
Argentina: Conrado Estol
Australia: Craig Anderson
Brazil: Gisele Sampaio Silva
Chile: Pablo Lavados
China: Yining Huang
France: Christian Stapf
India: Jeyaraj Durai Pandian
Norway: Elvind Berge
United Kingdom: Tom Robinson
Participating hospitals in INTERACT2 study:
National Stroke Foundation - voice of stroke in Australia - National Stroke Foundation – Australia. 2013. National Stroke
Foundation - voice of stroke in Australia - National Stroke Foundation – Australia. [ONLINE] Available at:
http://strokefoundation.com.au
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Argentina:
Clínica Adventista Belgrano – Luis
Alberto Camputaro
Clinica IMA – Héctor Perelmuter
Hospital Central – Andres Barboza
Hospital de Agudos “Juan A.
Fernandez”- German Fernandez
Hospital Privado de Comunidad – Pablo
Ioli
Hospital Prof. Dr. Luis Güemes – Pablo
Jose Schoon
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Australia:
Austin Hospital – Helen Dewey
Box Hill Hospital – Christopher Bladin
Concord Hospital – Alastair Corbett
Gosford Hospital – Jonathan Sturm
John Hunter Hospital – Mark Parsons
Monash Medical Centre – Thanh Phan
Royal Brisbane & Women’s Hospital –
Stephen Read
Royal Melbourne Hospital – Stephen
Davis
Royal Prince Alfred Hospital – Craig
Anderson
Sir Charles Gairdner Hospital – David
Blacker
St Vincent’s Hospital – Romesh Markus
The Canberra Hospital – Christian Lueck
Western Hospital – Tissa Wijeratne
Westmead Hospital – Andrew Evans
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Austria:
Allgemeines Krankenhaus Linz – Franz
Gruber
Medizinische Universität Graz – Franz
Fazekas
Medizinische Universität Innsbruck –
Erich Schmutzhard
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Belgium:
AZ Sint Blasius Dendermonde – Adinda
Depauw
CHU Tivoli – Patricia Redondo Saez
Clinique de l’Europe – Mathieu Rutgers
UCL Bruxelles – Andre Peeters
Universitair Ziekenhuis Brussel – Raf
Brouns
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Brazil:
Hospital das Clínicas de Porto Alegre –
Sheila Martins
Hospital das Clinicas de Ribeirao Preto
– Soraia Cabette
Hospital Espanhol – Jamary Oliveira
FIlho
Hospital Geral de Fortaleza – João José
Carvalho
Hospital Israelita Albert Einstein – Gisele
Sampaio Silva
Hospital Quinta D’Or – Gabriel Freitas
Hospital Santa Marcelina – Ana Cláudia
Ferraz de Almeida
Hospital São Paulo – Gisele Sampaio
Silva
Universidade Federal do Paraná –
Viviane H. Flumignan Zetola
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Chile:
Clinica Alemana, Santiago – J.M Montes
Clinica Alemana, Temuco – Rodrigo
Rivas S.
Clínica Dávila – Sergio Illanes
Complejo Asistencial Dr. Víctor Ríos
Ruiz – Christian Figueroa
Hospital Herminda Martin – Alexis Rojo
Hospital Naval – Pablo Araya
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China:
Beijing Shijitan Hospital (General
Railway Hospital) – He Maolin
Central Hospital, Changning District of
Shanghai – Tao Qingling
Changsha Central Hospital – Liu Zhuqin
Daxing County Hospital – Shi Fuming
Fourth Hospital of Jilin Medical
University – Cui Yong
Gongli Hospital, Pudong of Shanghai –
Sun Jian
Haidian Hospital, Beijing – Yu Fengchun
Hejian City People’s Hospital – Wang
Yanxia
Huashan Hospital – Dong Qiang
Hunan Province Brain Hospital – Huang
Xiaosong
Inner Mongolia Baotou City Central
Hospital – Li Yuechun
Jiangsu Province Hospital of TCM –
Jiang Yajun
Navy General Hospital – Qi Xiaokun
No. 3 People’s Hospital Affiliated to
Shanghai Jiao Tong University School of
Medicine – Zhu Youli
Peking University Shougang Hospital –
Ren Zhiping
Pinggu County Hospital, Beijing – Tan
Xiuge
Qinghai Province People’s Hospital –
Wu Shizheng
Qinghai University Affiliated Hospital –
Zhao Xiuli
Qinghuangdao Second Hospital – Lin
Xiaodong
Ruijin Hospital Affiliated to Shanghai
Second Medical University – Chen
Shengdi
Second Affiliated Hospital Suzhou
University – Liu Chunfeng
Second Hospital of Hebei Medical
University – Tai Liwen
Shijiazhuang 260 Hospital – Xu
Yuehong
The Affiliated Hospital of Xuzhou
Medical College – Xu Tie
The Branch Hospital of the First
People’s Hospital – Wang Shaoshi
The Chinese PLA No. 263 Hospital –
Zhang Jinli
The Fifth Affiliated Hospital Sun Yat-Sen
University – Li Zhendong
The First Affiliated Hospital of Baotou
Medical College – Wu Li’e
The First Affiliated Hospital of Beijing
University – Huang Yining
The First Affiliated Hospital of Fujian
Medical University – Wang Ning
The First Affiliated Hospital of Wenzhou
Medical College – Han Zhao
The First Hospital of Nanjing – Zhou
Junshan
The Second Affiliated Hospital of
Guangzhou Medical College – Xu En
The Second Affiliated Hospital of
Wenzhou Medical College – Zhang
Xiong
The Second Hospital of Tianjin Medical
University – Li Xin
Third Hospital of Hebei Medical
University – Liu JunYan
Tianjin Medical University General
Hospital – Cheng Yan
Tianjin Thrid Central Hospital – Zhang
Zhecheng
Tongren Hospital – Zhang Xiaojun
Wangcheng County People’s Hospital of
Hunan Province – Peng Xiaolan
Wuxi People’s Hospital – Zhang
Jianping
Xiangya Hospital of Changsha Central
South University – Yang Qidong
Xinhua Hospital Affiliated to Shanghai
Jiao Tong University School of Medicine
– Liu Zhenguo
Xining First People’s Hospital – Wang
Yuning
Xuzhou Central Hospital – Chen
Guogfang
Yutian County Hospital, Hebei Province
– Wang Jinchao
Zengcheng People’s Hospital – Zou
Rong
Zhangjiagang Traditional Chinese
Medicine Hospital – Qian Jufen
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Finland:
Helsinki University Central Hospital –
Soinne Lauri
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France:
Centre Hospitalier de Calais – Olivier
Dereeper
Centre Hospitalier de Meaux – Alain
Ameri
Centre Hospitalier de Versailles – AnneCecile Zeghoudi
Centre Hospitalier Sainte Anne –
Emmanuel Touze
CHU Bicetre – Christian Denier
CHU Nantes, Hopital Laennec – Benoit
Guillon
CHU Pontchaillou – Thomas Ronziere
Groupe Hospitalier Paris Saint-Joseph –
Mathieu Zuber
Hopital de la Cavale-Blanche – Serge
Timsit
Hopital de la Salpetrière – Sophie
Crozier
Hopital Delafontaine – Thomas De
Broucker
Hopital Jean Minjoz – Fabrice Vuillier
Hopital Lariboisière – Christian Stapf
Hopital Roger Salengro – Didier Leys
Hopital Tenon – Sonia Alamowitch
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Germany:
Charite Campus Benjamin Franklin –
Eric Jüttler
Klinikum Frankfurt – Andreas Hartmann
Martin Gropius Krankenhaus
Eberswalde – Hans Michael Schmitt
Universitätsklinikum Dresden – Hauke
Schneider
Universitätsklinikum Düsseldorf –
Sebastian Jander
Universitätsklinikum Frankfurt –
Christian Foerch
Universitätsklinikum Halle – Katja
Warternberg
Universitätsklinikum HamburgEppendorf – Michael Rosenkranz
Universitätsklinikum Mannheim –
Michael Hennerici
Universitätsklinikum Ulm, Oberer
Elselsberg – R. Huber
University of Heidelberg – Thorsten
Steiner
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Hong Kong:
Prince of Wales Hospital – Lawrence
Wong
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India:
Apollo Hospitals – Dedeepiya
Devaprasad
Apollo Hospitals – Subhashini Prabhakar
Baby Memorial Hospital - Ummer
Karadan
CARE Hospital – J Murali Krishna
Murthy
Christian Medical College – Jeyaraj
Pandian
GNRC Hospital – Nomal Chandra Borah
Jehangir Clinical Development Center –
Nasli R Ichaporia
Lalitha Super Speciality Hospital –
Vijaya Pamidimukkala
Post Graduate Institute of Medical
Education and Research – Dheeraj
Khurana
St. John’s Medical College and Hospital
– G R K Sarma
St. Theresa’s Hospital – Vikram Sharma
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Italy:
Neurologia-Nuovo Ospedale Civile
Modena – Andrea Zini
Ospedale di Branca – Stéfano Ricci
Ospedale di Citta’ di Castello – Stéfano
Ricci
Ospedale Riuniti di Foggia – Luigi
Specchio
Ospedale San Giovanni Battista Foligno
– Mauro Zampolini
Santa Corona Hospital – Tiziana
Tassinari
Sapienza University of Rome – Danilo
Toni
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Netherlands:
UMC Utrecht – Catharina JM Klijn
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North America:
Mayo Clinic – Alejandro Rabinstein
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Norway:
Helse Nord-Trøndelag HF Sykehuset
Namsos – Stephan Schüler
Helse Sunnmøre HF Ålesund sjukehus –
Yngve Müller Seljeseth
Oslo University Hospital Ullevaal –
Sigurd Vatn and Else Charlotte Sandset
Sørlandet sykehus HF Kristiansand –
Arnstein Tveiten
Sykehuset Innlandet HF Lillehammer –
Nils Holand
Universitetssykehuset Nord-Norge HF –
Stein Harald Johnsen
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Portugal:
Centro Hospitalar de Vila de Gaia –
Veloso Luis Miguel Galo
Porto Sao Joao – Guilherme Gama
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Spain:
Hospital Clinic Barcelona – Angel
Chamorro
Hospital de Girona Dr. Josep Trueta –
Yolanda Silva
Hospital General Universitario de
Albacete – Tomas Segura
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Switzerland:
Inselspital Neurologische Klinik Bern –
Urs Fischer
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United Kingdom:
Addenbrookes Hospital – Elizabeth
Warburton
Bristol Royal Infirmary – Sarah Caine
County Durham & Darlington NHS
Foundation Trust – Bernard Esisi
James Cook University Hospital – David
Broughton
John Radcliff Hospital – James Kennedy
Leeds General Infirmary – Ahamad
Hassan
Leicester Royal Infirmary – Amit Mistri
Musgrove Park Hospital – Robert
Whiting
New Cross Hospital – Kenneth Fotherby
Northumbria Healthcare Foundation
Trust – Christopher Price
Nottingham University Hospital –
Ganesh Subramanian
Queen Elizabeth Hospital, Gateshead –
Tim Cassidy
Queen Elizabeth the Queen Mother
Hospital – Gunaratnam Gunathilagan
Royal Bournemouth and Christchurch
Hospital – Damian Jenkinson
Royal Devon and Exeter Hospital –
Martin James
Royal Surrey County Hospital – Adrian
Blight
Royal United Hospital – Louise Shaw
Royal Victoria Infirmary – Anand Dixit
Salford Royal Hospital – Adrian ParryJones
St Georges Hospital – Caroline Lovelock
St. Thomas Hospital – Ajay Bhalla
University College Hospital – David
Werring
University Hospital of North Staffordshire
– Christine Roffe
William Harvey Hospital – David
Hargroves
The George Institute for Global Health is improving the lives of millions of people worldwide through
innovative health research. Working across a broad health landscape, the Institute conducts clinical,
population and health system research aimed at changing health practice and policy worldwide. The
Institute has a global network of medical and health experts working together to address the leading
causes of death and disability worldwide. Established in Australia and affiliated with The University of
Sydney, the Institute today also has offices in China, India and the United Kingdom, and is also
affiliated with Peking University Health Science Centre, the University of Hyderabad and the
University of Oxford.