African Traditional Herbal Research Clinic Why Africa Fears Western Medicine NEWSLETTER
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African Traditional Herbal Research Clinic Why Africa Fears Western Medicine NEWSLETTER
African Traditional Herbal Research Clinic NEWSLETTER Volume 3, Issue 9 October 2008 HONORING THE AFRICAN TRADITIONAL HERBALIST HIV/AIDS - MALARIA Why Africa Fears Western Medicine By Harriet A.Washington July 31, 2007 Op-Ed Contributor TO Westerners, the repatriation of five nurses and a doctor to Bulgaria last week after more than eight years’ imprisonment meant the end of an unsettling ordeal. The medical workers, who in May 2004 were sentenced to death on charges of intentionally infecting hundreds of Libyan children with H.I.V., have been freed, and another international incident is averted. But to many Africans, the accusations, which have been validated by a guilty verdict and a promise to reimburse the families of the infected children with a $426 million payout, seem perfectly plausible. The medical workers’ release appears to be the latest episode in a health care nightmare in which white and Western-trained doctors and nurses have harmed Africans — and have gone unpunished. Continued on page 2 INSIDE THIS ISSUE 1 Why Africa Fears Western Medicine 3 Afrikan Spirituality-Challenges Facing Indigenous Knowledge 4 Feature – Ancient African Medicine, Egypt and the World 6 Feature – Med Schools, Journals Fight Big Pharma’s Sway 7 Pathologists Believe They Have Pinpointed Achilles Heel of HIV 8 Feature – WHO Murdered Africa 14 Threat of World Aids Pandemic Among Heterosexuals is Over 15 Common Gene makes Africans more Vulnerable to HIV 16 Feature – What are Duffy Antigens? 19 Malaria Drug Contributing to Antibiotic Resistance 20 Malaria Fuels HIV Spread 21 Scientists Map Genomes of Malaria Parasite 25 Feature – The African Traditional Herbal Research Centre 27Traditional Medicine Playing Important Role 30 More Herbal Medicine Flood Ugandan Markets 32 Ugandans Now Live Up to 50 Years 33 Feature – Unified Field Theory of Disease 36 Researcher Record Major Breakthrough Against Malaria 42 HIV Hides from Drugs for Years 44 Drug Factors Sub-Standard 49 Farmers Reap Fortunes of Malaria Treatment 54 Herb Of The Month – Bridelia micrantha & More What is the African Traditional Herbal Research Clinic? We can make you healthy and wise Nakato Lewis Blackherbals at the Source of the Nile, UG Ltd. The African Traditional Herbal Research Clinic located in Bukoto, Uganda is a modern clinic facility created to establish a model space whereby indigenous herbal practitioners and healers can upgrade and update their skills through training and certification and respond to common diseases using African healing methods and traditions in a modern clinical environment. Traditional healers are the major health labor resource in Africa as a whole. In Uganda, indigenous traditional healers are the only source of health services for the majority of the population. An estimated 80% of the population receives its health education and health care from practitioners of traditional medicine. They are knowledgeable of the culture, the local languages and local traditions. Our purpose is to raise public awareness and understanding on the value of African traditional herbal medicine and other healing practices in today’s world. The Clinic is open and operational. Some of the services we offer are African herbal medicine, reflexology, acupressure, hot and cold hydrotherapy, body massage, herbal tonics, patient counseling, blood pressure checks, urine testing (sugar), and nutritional profiles. We believe in spirit, mind and body. Spiritual counseling upon request. Visit us also at www.Blackherbals.com Hours: 9:00 am to 6:00 pm Monday thru Friday 10 am to 4:00 pm Saturday - Sundays – Closed -1-Traditional African Clinic – October 2008 Continued from page 1 – Why Africa Fears Western Medicine The evidence against the Bulgarian medical team, like H.I.V.-contaminated vials discovered in their apartments, has seemed to Westerners preposterous. But to dismiss the Libyan accusations of medical malfeasance out of hand means losing an opportunity to understand why a dangerous suspicion of medicine is so widespread in Africa. Africa has harbored a number of high-profile Western medical miscreants who have intentionally administered deadly agents under the guise of providing health care or conducting research. In March 2000, Werner Bezwoda, a cancer researcher at South Africa’s Witwatersrand University, was fired after conducting medical experiments involving very high doses of chemotherapy on black breast-cancer patients, possibly without their knowledge or consent. In Zimbabwe, in 1995, Richard McGown, a Scottish anesthesiologist, was accused of five murders and convicted in the deaths of two infant patients whom he injected with lethal doses of morphine. And Dr. Michael Swango, ultimately convicted of murder after pleading guilty to killing three American patients with lethal injections of potassium, is suspected of causing the deaths of 60 other people, many of them in Zimbabwe and Zambia during the 1980s and ’90s. (Dr. Swango was never tried on the African charges.) These medical killers are well known throughout Africa, but the most notorious is Wouter Basson, a former head of Project Coast, South Africa’s chemical and biological weapons unit under apartheid. Dr. Basson was charged with killing hundreds of blacks in South Africa and Namibia, from 1979 to 1987, many via injected poisons. He was never convicted in South African courts, even though his lieutenants testified in detail and with consistency about the medical crimes they conducted against blacks. Such well-publicized events have spread a fear of medicine throughout Africa, even in countries where Western doctors have not practiced in significant numbers. It is a fear the continent can ill afford when medical care is already hard to come by. Only 1.3 percent of the world’s health workers practice in sub-Saharan Africa, although the region harbors fully 25 percent of the world’s disease. A minimum of 2.5 health workers is needed for every 1,000 people, according to standards set by the United Nations, but only six African countries have this many. The distrust of Western medical workers has had direct consequences. Since 2003, for example, polio has been on the rise in Nigeria, Chad and Burkina Faso because many people avoid vaccinations, believing that the vac- cines are contaminated with H.I.V. or are actually sterilization agents in disguise. This would sound incredible were it not that scientists working for Dr. Basson’s Project Coast reported that one of their chief goals was to find ways to selectively and secretly sterilize Africans. Such tragedies highlight the challenges facing even the most idealistic medical workers, who can find themselves working under unhygienic conditions that threaten patients’ welfare. Well-meaning Western caregivers must sometimes use incompletely cleaned or unsterilized needles, simply because nothing else is available. These needles can and do spread infectious agents like H.I.V. — proving that Western medical practices need not be intentional to be deadly. Although the World Health Organization maintains that the reuse of syringes without sterilization accounts for only 2.5 percent of new H.I.V. infections in Africa, a 2003 study in The International Journal of S.T.D. and AIDS found that as many as 40 percent of H.I.V. infections in Africa are caused by contaminated needles during medical treatment. Even the conservative W.H.O. estimate translates to tens of thousands of cases. Several esteemed science journals, including Nature, have suggested that the Libyan children were infected in just this manner, through the re-use of incompletely cleaned medical instruments, long before the Bulgarian nurses arrived in Libya. If this is the case, then the Libyan accusations of iatrogenic, or healer-transmitted, infection are true. The acts may not have been intentional, but given the history of Western medicine in Africa, accusations that they were done consciously are far from paranoid. Certainly, the vast majority of beneficent Western medical workers in Africa are to be thanked, not censured. But the canon of “silence equals death” applies here: We are ignoring a responsibility to defend the mass of innocent Western doctors against the belief that they are not treating disease, but intentionally spreading it. We should approach Africans’ suspicions with respect, realizing that they are born of the acts of a few monsters and of the deadly constraints on medical care in difficult conditions. By continuing to dismiss their reasonable fears, we raise the risk of even more needless illness and death. Harriet A. Washington is the author of “Medical Apartheid: The Dark History of Medical Experimentation on Black Americans From Colonial Times to the Present.” http://www.nytimes.com/2007/07/31/opinion/31washington.html ☻☻☻☻☻☻ -2-Traditional African Clinic – October 2008 ☻☻☻☻☻☻ AFRIKAN SPIRITUALITY CHALLENGES FACING INDIGENOUS KNOWLEDGE BY: KABATABAZI PATRICIA ENVIRONMENTALIST It is commonly accepted that we are living in the “information age”. We are generators of vast knowledge. True as it may seem, it has been noted that the present generation is actually losing more information than it is acquiring. Most shocking is the erosion of culturally based knowledge represented by thousands of disappearing (RAFI, 1997). For example, experts in linguistics note that half of the 6000 languages spoken in the world will die out during the 21st century. As each language vanishes, tens of thousands of years of cultural heritage and indigenous knowledge is lost. Loss of this cultural diversity is intricately linked with loss of agricultural biodiversity. Loss of biodiversity puts at stake food security and nutrition and overall agricultural development. The movement of people is leading to loss of farming communities, languages and indigenous cultures; all represent the erosion of human intellectual capital on massive scale. Development of sustainable agriculture systems depends upon the innovative capacity of farmers, forest dwellers, pastoralists, and fisher-folk together with their accumulated knowledge. Therefore, recognising, rewarding and protecting indigenous knowledge systems is critical for agricultural development, food security and nutrition. Successful strategies should be formulated and implemented to save our indigenous knowledge through environmental impact assessment awareness/research, documentation, and publication. “The responsibility of conserving our indigenous knowledge is for all of us, white and black. We came from one person, our CREATOR.” In Africa, I salute our great ancestors who carried out studies on nature-given resources to name items as food, medicine, shelter materials etc for our use. This valuable intellect has been passed on from generation to generation mainly in verbal communication. We are quite an intelligent race to preserve information in that way for many centuries without any written text to be left behind for the ________________________ Managing Editor: Nakato Lewis PUBLISHER: KIWANUKA LEWIS Published monthly and freely by BHSN for the African Traditional Herbal Research Clinic The traditional shrine as a symbol of our cultural history coming generations, until writing finally reached Africa for us to access it and preserve the knowledge. The light of knowledge in Africa remained burning and it is still burning even through the interventions of Arabs and colonial masters. These external forces nearly exterminated the pillars of African education in skills and technology. The intruders` referred to Africa knowledge of skills and technology as satanic, primitive, backward and outdated, even up to today. Given the nature of Lake Nalubale (Victoria) basin climate, soil types and fresh waters, these three are responsible for the wealth of biodiversity of plants, animals, ants, birds etc. People of the ancient past took advantage of the environment and were able to survive many problems using the environment as answers to overcome their day to-day challenges. In Africa, each item is believed to belong to the Almighty, the creator, giver and overseer of all creations, visible and invisible ones. And that invisible power of creation is believed to be the giver and taker of life. The second way an African perceives nature is by way of association and identification of themselves with in terms of totems, clans, etc. The third way Africans have looked at nature is by taboos. It is taboo whenever a member in any one's given community treated nature in a way perceived to result in spoiling or destruction of the status quo. The fourth way is to have sacred people, animals, rocks, caves, trees, rivers, mountains etc. The list is endless, but the important aspect in all these efforts is to create controls and wise use and management of nature- given resources. Recommendation: There is need to carryout research on the culture aspect for sustainable use of natural resources. There should be functional and participatory research in the world. There is a need to integrate our cultural aspects into modern ways for natural resource management. -3-Traditional African Clinic – October 2008 ☻☻☻☻☻☻ African Traditional Herbal Research Clinic Volume 3, Issue 9 NEWSLETTER October 2008 FEATURED ARTICLES Ancient African Medicine, Egypt, (Khemit) and the World By Jide Iwechia June 08, 2007 Interestingly, certain remedies prescribed by Egyptian physicians were way ahead of modern anticipation. For instance, celery and saffron which were used for rheumatism are currently hot topics of pharmaceutical research, and pomegranate was used to eradicate tapeworms, a remedy that remained in clinical use until 50 years ago. Acacia is still used in cough remedies while aloes form a basis to soothe and heal skin conditions. The knowledge and the uses of essential oils and resins were introduced to the world by the ancient Egyptians.” The early Egyptians appear to have been the first to recognize that stress could contribute to illness. They established sanitariums where people would undergo “dream therapy” and treatments with “healing waters. It is now official! The western propaganda press and its scholarly co-conspirators in the academia have finally admitted that African Khemit gave the world the gift of medical sciences as opposed to previously peddled lies which identify Greece as the origin of medicine. Imhotep, the Prince of Peace, the Egyptian inventor of medicine and healing was a real historical African genius who received the book of healing from the mysterious forces of ancestral Africa. This book was later given to the world and it forms the basis of modern medicine and surgery. The entire ancient world, including the ancient Greeks celebrated this venerable old man of wisdom who was synonymous with ingenuity. Even Hippocrates, socalled Greek Father of Modern Medicine was a devotee of Imhotep the Prince of Peace. Scientists examining documents dating back more than 3,500 years have confirmed that the origins of modern medicine lie in ancient Egypt and not with Hippocrates and the Greeks. The medical papyri were written in 2,500 BC – 1,000, thousands of years before Hippocrates was born. The medical documents were first discovered in the mid-19th century but then suppressed because it demonstrated facts which were antithetical to the official but hypocritical racist attitudes which then prevailed. According to one of the scientists, Dr Jackie Campbell: “Classical scholars have always considered the ancient Greeks, particularly Hippocrates, as being the fathers of medicine but our findings suggest that the ancient Egyptians were practising a credible form of pharmacy and medicine much earlier,” “When we compared the ancient remedies against modern pharmaceutical protocols and standards, we found the prescriptions in the ancient documents not only compared with pharmaceutical preparations of today but that many of the remedies had therapeutic merit.” “Many of the ancient remedies we discovered survived into the 20th century and, indeed, some remain in use today, albeit that the active component is now produced synthetically.” Imhotep Imhotep was the world’s first named physician, and the architect who built Egypt’s first pyramid. He is indisputedly the world’s first doctor, a priest, scribe, sage, poet, astrologer, a vizier and chief minister, to Djoser (reigned 2630–2611 BC), the second king of Egypt’s third dynasty. An inscription on one of that king’s statues gives us Imhotep’s titles as the “the prince of peace,” “chancellor of the king of lower Egypt,” the “first one under the king,” the “administrator of the great mansion,” the “hereditary Noble,” the “high priest of Heliopolis,” the “chief sculptor,” and finally the “chief carpenter”. -4-Traditional African Clinic – October 2008 Continued on page 5 Continued from page 8 – Ancient African Medicine As a builder, Imhotep is the first recorded master architects. He was the first pyramid architect and builder, and among his works one counts the Djoser’s Step Pyramid complex at Saqqara, Sekhemkhet’s unfinished pyramid, and possibly the Edfu Temple. The Step Pyramid remains today one of the most brilliant architecture wonders of the ancient world and is recognized as the first monumental stone structure. Devotees bought offerings to his medical and spiritual school in Saqqara, including mummified Ibises and sometimes, in the hope of being healed. He was later even worshipped by the early Christians as one with Christ who was made to adopt one of the titles of Imhotep, “the Prince of Peace”. The early Christians often appropriated those pagan forms and persons whose influence through the ages had woven itself so powerfully into tradition that they could not omit them. Imhotep was also the first known physician, medical professor and a prodigous writer of medical books. As the first medical professor, Imhotep is believed to have been the author of the Edwin Smith Papyrus in which more than 90 anatomical terms and 48 injuries are described. He was worshiped in Greece where he was identified with their god of medicine, Aslepius. He was honored by the Romans and inscriptions praising Imhotep were placed on the walls of Roman temples. Most surprisingly, he even managed to find a place in Arab traditions, especially at Saqqara where his tomb is thought to be located. He also founded a school of medicine in Memphis, possibly known as “Asklepion, which remained famous for two thousand years. All of this occurred some 2,200 years before the Western Father of Medicine Hippocrates was born. Materia Medica The ancient Egyptian physicians treated wounds with honey, resins (including cannabis resin) and elemental metals known to be antimicrobial. This practice is still a valid medical protocol even today. According to Sir William Osler, Imhotep was the: “..first figure of a physician to stand out clearly from the mists of antiquity.” Imhotep diagnosed and treated over 200 diseases, 15 diseases of the abdomen, 11 of the bladder, 10 of the rectum, 29 of the eyes, and 18 of the skin, hair, nails and tongue. Imhotep treated tuberculosis, gallstones, appendicitis, gout and arthritis. He also performed surgery and practiced some dentistry. Imhotep extracted medicine from plants. He also knew the position and function of the vital organs and circulation of the blood system. The Encyclopedia Britannica says, “The evidence afforded by Egyptian and Greek texts support the view that Imhotep’s reputation was very respected in early times. His prestige increased with the lapse of centuries and his temples in Greek times were the centers of medical teachings.” Again, just like in these modern times, the prescriptions for laxatives included castor oil and colocynth and bulk bran and figs were used to promote regularity. Along with medicine, he was also a patron of architects, knowledge and scribes. James Henry Breasted says of Imhotep: “In priestly wisdom, in magic, in the formulation of wise proverbs; in medicine and architecture; this remarkable figure of Zoser’s reign left so notable a reputation that his name was never forgotten. He was the patron spirit of the later scribes, to whom they regularly poured out a libation.” Imhotep was, together with Amenhotep, the only mortal Egyptians that ever reached the position of full gods. He was also associated with Thoth, the god of wisdom, writing and learning, and with the Ibises, which was also associated with Thoth. Other references show that colic was treated with hyoscyamus, which is still used today, and that cumin and coriander were used as intestinal carminatives. Musculo-skeletal disorders were treated with rubefacients to stimulate blood flow and poultices to warm and soothe similar to the practices of modern practitioners of sports medicine. Interestingly, certain remedies prescribed by Egyptian physicians were way ahead of modern anticipation. For instance, celery and saffron which were used for rheumatism are currently hot topics of pharmaceutical research, and pomegranate was used to eradicate tapeworms, a remedy that remained in clinical use until 50 years ago. Acacia is still used in cough remedies while aloes forms a basis to soothe and heal skin conditions. The knowledge and the uses of essential oils and resins were introduced to the world by the ancient Egyptians.” The early Egyptians appear to have been the first to recognize that stress could contribute to illness. They established sanitariums where people would undergo “dream therapy” and treatments with “healing waters. Altogether, around 50 percent of the plants used in ancient Egypt remain in clinical use today. Many of the medical and surgical instruments such as knives and forceps have -5-Traditional African Clinic – October 2008 Continued on page 13 African Traditional Herbal Research Clinic Volume 3, Issue 9 NEWSLETTER October 2008 FEATURED ARTICLES Med Schools, Journals Fight Big Pharma’s Sway Even as new guidelines are set, potential for conflict remains, say many The Associated Press September 10, 2008 TRENTON, N.J. - Just about every segment of the medical community is piling on the pharmaceutical industry these days, accusing drugmakers of deceiving the public, manipulating doctors and putting profits before patients. Recent articles and editorials in major medical journals blast the industry. Medical schools, teaching hospitals and physician groups are changing rules to limit the influence of pharmaceutical sales reps. And three top editors of the prestigious New England Journal of Medicine last month publicly sided against the drug industry in a U.S. Supreme Court case over whether patients harmed by government-approved medicines may still sue in state courts. As more voices have called for change, new guidelines for how drugmakers and doctors should interact are coming from both industries, and doctors say some abuses of the past have ended. But the industries’ dealings remain fraught with potential conflict because the sectors depend on each other so much — medicine on drugmakers’ research dollars and drugmakers on the credibility researchers give them. “The influence that the pharmaceutical companies, the for-profits, are having on every aspect of medicine ... is so blatant now you’d have to be deaf, blind and dumb not to see it,” said Journal of the American Medical Association editor Dr. Catherine DeAngelis, a longtime industry critic. “We have just allowed them to take over, and it’s our fault, the whole medical community.” In an April editorial in her journal, DeAngelis noted two studies indicated past reports about Merck & Co.’s withdrawn pain reliever Vioxx frequently were penned by ghostwriters and that reports on some Vioxx studies minimized the risk of death. Merck has denied the charges. “Manipulation of studies and publications by the pharmaceutical and medical device industries is either increasing or there has been more exposure of these practices,” she wrote. “We should say "Enough!" She said industry influence includes swaying doctors and medical students to their brands with gifts, funding research at top teaching hospitals but keeping control of the studies and results, failing to disclose study authors’ conflicts of interest, even taking over the continuing medical education system for doctors by running courses on new treatments. Critics say such courses are taught by company-paid speakers who often promote expensive new drugs over older, cheaper ones. “We should all get together and say, ’Enough!”’ DeAngelis said. Already, top journals are listing study authors’ conflicts of interest, and dozens of medical schools and medical specialty societies are barring gifts to doctors and limiting their other financial ties to industry. Some schools bar professors from being paid drug company’s speakers. And one expert noted drugmakers have stopped giving cash prizes to medical students for presenting favorable research on their drugs at conferences. Still, no one is suggesting anything as drastic as cutting off industry funding for academic research on new drugs. Those billions help pay lab and other expenses at virtually all U.S. teaching hospitals, medical schools and affiliated practices, while giving the drugs’ developers the cachet of having big-name academic researchers running their studies. The industry’s trade group, in an apparent response, in July revised its 2002 “Code on Interactions with Healthcare Professionals” to ban giving out pens, mugs and other noneducational gifts, taking doctors to restaurants and giving them tickets for shows or sports events. Bringing meals to their offices and donating anatomical models and textbooks will still be allowed when the voluntary code takes effect in January. “America’s pharmaceutical companies devote many years and billions of dollars to researching and develop- -6-Traditional African Clinic – October 2008 Continued on page 7 Continued from page 6 – Med Schools, Journals Fight Big Pharma ing life-saving medicines,” and help drive progress and economic growth, said Diane Bieri, general counsel for Pharmaceutical Research and Manufacturers of America. “We will always face criticism and at times deserve it but our companies remain committed to listening to and learning from parties with divergent points of views.” Hollie Gilroy, spokeswoman for the HealthCare Institute of New Jersey, a trade group including many top drugmakers, said the industry is an easy target, but criticisms about gifts to doctors, beyond logo-bearing pens and similar items, are either outdated or exaggerated. She said the industry is quick to police itself and tries to keep high ethical standards when dealing with health-care professionals. “There is no industry far and away that has been more generous than the pharmaceutical industry,” Gilroy added, noting companies give away medication samples, fund large prescription assistance programs for the poor, have helped African countries get AIDS medications, and donate drugs and medical supplies after major disasters. But pharmaceutical analyst Steve Brozak of WBB Securities said drugmakers will find ways to adapt to new rules. “The earlier you can hook one of these doctors, the more loyal they are” to a brand, Brozak said. Medical groups have been fighting industry influence harder since a 2006 JAMA editorial by 11 prominent doctors urged teaching hospitals to lead in cleaning up conflicts of interest between medicine and industry. New Web site shows med schools policies David Rothman, president of the Institute on Medicine as a Profession, said about one-fourth of U.S. medical schools now have policies on industry gifts “that really pass muster.” Some bar sales reps from giving doctors drug samples — but allow donations to a central supply office — and don’t let them wander their halls to speak to doctors. “You’re not being bribed, you’re being gifted,” doctors may think, but industry freebies influence prescribing patterns, Rothman said. On Wednesday, his group launched the first public database showing detail conflict of interest policies at most of the 125 U.S. academic medical centers. At University of Pittsburgh School of Medicine, possibly the strictest, pharmaceutical reps since February have had to get a perfect score on an online training program about its rules to get appointments. Some reps have been warned about infractions, but none have been banned, said Dr. Barbara Barnes, head of industry relations. Rothman said there’s a new effort to “clean up” continuing medical education of doctors, the only professionals he knows who don’t pay for it themselves. In June, the Association of American Medical Colleges put out guidelines that bar drugmakers from paying for continuing medical education sessions on specific topics but allow donations to a central fund. The Council of Medical Specialty Societies, which represents 32 specialty groups, this summer, started collecting each group’s best practices on disclosure and limitations on speaking and other activities by their officers. Council CEO Dr. Norman Kahn said a new council policy should be ready in November. Meanwhile, Sen. Charles Grassley of Iowa, a frequent industry critic, is sponsoring a bill to require drugmakers to report all payments to doctors — from buying meals to flying them to conferences at resorts. Doctors say there’s more to be done, but see an impact. Dr. Marc Siegel, an internist and associate professor at New York University School of Medicine, said the school has fewer drugmaker-sponsored events, and he no longer gets offers of baseball tickets or paid junkets as a consultant at a doctors’ meeting — things he turned down anyway. He said some colleagues no longer let drug sales reps in their offices, but he does. “I don’t mind — I like my staff to get a free lunch,” Siegel said. “I don’t think it influences one iota what I prescribe.” http://www.msnbc.msn.com/id/26622463/ ☻☻☻☻☻☻ Pathologists Believe They Have Pinpointed Achilles Heel of HIV ScienceDaily (July 16, 2008) — Human Immunodeficiency Virus (HIV) researchers at The University of Texas Medical School at Houston believe they have uncovered the Achilles heel in the armor of the virus that continues to kill millions. The weak spot is hidden in the HIV envelope protein gp120. This protein is essential for HIV attachment to host cells, which initiate infection and eventually lead to Acquired Immunodeficiency Syndrome or AIDS. Normally the body’s immune defenses can ward off viruses by making proteins called antibodies that bind the virus. However, HIV is a constantly changing and mutating virus, and the antibodies produced after -7- Traditional African October 2008 Continued on page 10 African Traditional Herbal Research Clinic Volume 3, Issue 9 NEWSLETTER October 2008 FEATURED ARTICLES WHO MURDERED AFRICA - Excerpts By William Campbell Douglas, M.D. There is no question mark after the title of this article because the title is not a question. It's a declarative statement. WHO, the World Health Organization, murdered Africa with the AIDS virus. That's a provocative statement, isn't it? The answers to this little mystery, Murder on the WHO Express, will be quite clear to you by the end of this report. You will also understand why the other suspects, the homosexuals, the green monkey and the Haitians, were only pawns in this virocidal attack on the world. If you believe the government propaganda that AIDS is hard to catch then you are going to die even sooner than the rest of us. The common cold is a virus. Have you ever had a cold? How did you catch it? You don't really know, do you? If the cold virus were fatal how many people would there be left in the world? Yellow fever is a virus. You catch it from mosquito bites. Malaria is a parasite also carried by mosquitoes. It is many times larger than the AIDS virus (like comparing a pinhead to a moose head) yet the mosquito easily carries this large organism to man. The tuberculosis germ, also, much larger than the AIDS virus, can be transmitted by fomites (inanimate objects such as towels). The AIDS virus can live for as long as 10 days on a dry plate. You can't understand this murder mystery unless you learn a little virology. Many viruses grow in animals and many grow in humans, but most of the viruses that affect animals don't affect humans. There are exceptions, of course, such as yellow fever and small pox. There are some viruses in animals that cause very lethal cancer in those animals, but do not affect man or other animals. The bovine leukemia virus (BLV), for example, is lethal to cows but not humans. There is another virus that occurs in sheep called sheep visna virus which is also non-reactive in man. These deadly viruses are "retro viruses" meaning that they can change the genetic composition of cells that they enter. The World Health Organization, in published articles, called for scientists to work with these deadly agents and attempt to make a hybrid virus that would be deadly to humans: "And attempt should be made to see if viruses can in fact exert selective effects on immune function. The possibility should be looked into that the immune response to the virus itself may be impaired if the infecting virus damages, more or less selectively, the cell responding to the virus." That's AIDS. What the WHO is saying in plain English is "Let's cook up a virus that selectively destroys the T-cell system of man, an acquired immune deficiency." Why would anyone want to do this? If you destroy the Tcell system of man you destroy man. Is it even remotely possible that the World Health Organization would want to develop a virus that would wipe out the human race? If their new virus creation worked, the WHO stated, then many terrible and fatal infectious viruses could be made even more terrible and more malignant. Does this strike you as being a peculiar goal for a health organization? Sometimes Americans believe in conspiracies and sometimes they don't. Was there a conspiracy to kill President Kennedy? Twenty-five years later the debate still continues, and people keep changing their minds. One day it's yes, the next day it's no-depending on what was served for breakfast or how the stock market did the day before. But what about the green monkey? Some of the best virologist in the world and many of those directly involved in AIDS research, such as Robert Gallo and Luc Montagnier, have said that the green monkey may be the culprit. You know the story: A green monkey bit a native on the ass and, bam-AIDS all over central Africa. There is a fatal flaw here. It is very strange. Because Gallo, Montagnier and these other virologists know that the AIDS virus doesn't occur naturally in monkeys. -8- Traditional African Clinic October 2008 Continued on page 9 Continued from page 8 – WHO Murdered Africa In fact it doesn't occur naturally in any animal. AIDS started practically simultaneously in the United States, Haiti, Brazil, and Central Africa. (Was the green monkey a jet pilot?) Examination of the gene structure of the green monkey cells proves that it is not genetically possible to transfer the AIDS virus from monkeys to man by natural means. Because of the artificial nature of the AIDS virus it will not easily transfer from man to man until it has become very concentrated in the body fluids through repeated injections from person to person, such as drug addicts, and through high multiple partner sexual activity After repeated transfer it can become a "natural" infection for man, which it has. Dr. Theodore Strecker's research of the literature indicates that the National Cancer Institute in collaboration with the World Health Organization made the AIDS virus in their laboratories at Fort Detrick (now NCI). They combined the deadly retroviruses, bovine leukemia virus and sheep visna virus, and injected them into human tissue cultures. The result was the AIDS virus, the first human retrovirus known to man and now believed to be 100 percent fatal to those infected. The momentous plague that we now face was anticipated by the National Academy of Sciences (NAS) in 1974 when they recommended that "Scientists throughout the world join with the members of this committee in voluntarily deferring experiments (linking) animal viruses." What the NAS is saying in carefully guarded English is: "For God's sake, stop this madness!" The creation of the AIDS virus by the WHO was not just a diabolical scientific exercise that got out of hand. It was a cold-blooded successful attempt to create a killer virus which was then used in a successful experiment in Africa. So successful in fact that most of central Africa may be wiped out, 75,000,000 dead within 3-5 years. It was not an accident. It was deliberate. In the Federation Proceedings of the United States in 1972, WHO said: "In the relation to the immune response a number of useful experimental approaches can be visualized." They suggested that a neat way to do this would be to put their new killer virus (AIDS) into a vaccination program, sit back and observe the results. "This would be particularly informative in siblings," they said. That is, give the AIDS virus to brothers and sisters and see if they die, who dies first, and of what, just like using rats in a laboratory. They used smallpox vaccine for their vehicle and the geographical sites chosen in 1972 were Uganda and other African states, Haiti, Brazil and Japan. The present or recent past of AIDS epidemiology coincides with these geographical areas. Dr. Strecker points out that even if the African green monkey could transmit AIDS to humans, the present known amount of infection in Africa makes it statistically impossible for a single episode, such as a monkey biting someone, to have brought this epidemic to this point. The doubling time of the number of people infected, about every 14 months, when correlated with the first known case, and the present known number of cases, prove beyond a doubt that a large number of people had to have been infected at the same time. Starting in 1972 with the first case from our mythical monkey and doubling the number infected from that single source every 14 months you get only a few thousand cases. From 1972 to 1987 is 15 years or 180 months. If it takes 14 months to double the number of cases then there would have been 13 doublings, 1 then 2, then 4, then 8, etc. In 15 years, from a single source of infection there would be about 8,000 cases in Africa, not 75 million AIDS infected people. We are approaching World War II mortality statistics herewithout a shot being fired. Dr. Theodore A. Strecker is the courageous doctor who unraveled this conundrum, the greatest murder mystery of all time. He should get the Nobel Prize but he'll be lucky not to get "suicided." ("Prominent California doctor ties his hands behind his back, hangs himself, and jumps from 20th floor. There was no evidence of foul play.") Strecker was employed as a consultant to work on a health proposal for Security Pacific Bank. He was to estimate the cost of their health care for the future. Should they form a health maintenance organization? (HMO) was a major issue. After investigating the current medical market he advised against the HMO because he found that the AIDS epidemic will in all probability bankrupt the nation's medical system. He became fascinated with all the peculiar scientific anomalies concerning AIDS that kept cropping up. Why did the "experts" keep talking about green monkeys and homosexuals being the culprits when it was obvious that the AIDS virus was a man-made virus? Why did they say that it was a homosexual and drug-user disease when in Africa it was obviously a heterosexual disease? If the green monkey did it, then why did AIDS explode practically simultaneously in Africa, Haiti, Brazil, the United States and southern Japan? Why, when it was proposed to the National Institute of Health that the AIDS virus was a combination of two bovine or sheep viruses cultured in human cells in a -9- Traditional African Clinic October 2008 Continued on page 11 Continued from page 7–Pathologists Believe They Have pinpointed A. Heel of HIV infection do not control disease progression to AIDS. For the same reason, no HIV preventative vaccine that stimulates production of protective antibodies is available. The Achilles heel, a tiny stretch of amino acids numbered 421-433 on gp120, is now under study as a target for therapeutic intervention. Sudhir Paul, Ph.D., pathology professor in the UT Medical School, said, “Unlike the changeable regions of its envelope, HIV needs at least one region that must remain constant to attach to cells. If this region changes, HIV cannot infect cells. Equally important, HIV does not want this constant region to provoke the body’s defense system. So, HIV uses the same constant cellular attachment site to silence B lymphocytes - the antibody producing cells. The result is that the body is fooled into making abundant antibodies to the changeable regions of HIV but not to its cellular attachment site. Immunologists call such regions superantigens. HIV’s cleverness is unmatched. No other virus uses this trick to evade the body’s defenses.” Paul is the senior author on a paper about this theory in a June issue of the journal Autoimmunity Reviews. Additional data supporting the theory are to be presented at the XVII International AIDS Conference Aug. 3-8 in Mexico City in two studies titled “Survivors of HIV infection produce potent, broadly neutralizing IgAs directed to the superantigenic region of the gp120 CD4 binding site” and “Prospective clinical utility and evolutionary implication of broadly neutralizing antibody fragments to HIV gp120 superantigenic epitope.” First reported in the early 1980s, HIV has spread across the world, particularly in developing countries. In 2007, 33 million people were living with AIDS, according to a report by the World Health Organization and the United Nations. Paul’s group has engineered antibodies with enzymatic activity, also known as abzymes, which can attack the Achilles heel of the virus in a precise way. “The abzymes recognize essentially all of the diverse HIV forms found across the world. This solves the problem of HIV changeability. The next step is to confirm our theory in human clinical trials," Paul said. have identified antibodies that, instead of passively bind ing to the target molecule, are able to fragment it and destroy its function. Their recent work indicates that naturally occurring catalytic antibodies, particularly those of the IgA subtype, may be useful in the treatment and prevention of HIV infection,” said Steven J. Norris, Ph.D., holder of the Robert Greer Professorship in the Biomedical Sciences and vice chair for research in the Department of Pathology and Laboratory Medicine at the UT Medical School at Houston. The abzymes are derived from HIV negative people with the autoimmune disease lupus and a small number of HIV positive people who do not require treatment and do not get AIDS. Stephanie Planque, lead author and UT Medical School at Houston graduate student, said, “We discovered that disturbed immunological events in lupus patients can generate abzymes to the Achilles heel of HIV. The human genome has accumulated over millions of years of evolution a lot of viral fragments called endogenous retroviral sequences. These endogenous retroviral sequences are overproduced in people with lupus, and an immune response to such a sequence that resembles the Achilles heel can explain the production of abzymes in lupus. A small minority of HIV positive people also start producing the abzymes after decades of the infection. The immune system in some people can cope with HIV after all.” Carl Hanson, Ph.D., who heads the Retrovirus Diagnostic Section of the Viral and Rickettsial Disease Laboratory of the California Department of Public Health, has shown that the abzymes neutralize infection of human blood cells by diverse strains of HIV from various parts of the world. Human blood cells are the only cells that HIV infects. “This is an entirely new finding. It is a novel antibody that appears to be very effective in killing the HIV virus. The main question now is if this can be applied to developing vaccine and possibly used as a microbicide to prevent sexual transmission,” said David C. Montefiori, Ph.D., director of the Laboratory for AIDS Vaccine Research & Development at Duke University Medical Center. The abzymes are now under development for HIV immunotherapy by infusion into blood. They could also be used to guard against sexual HIV transmission as topical vaginal or rectal formulations. Unlike regular antibodies, abzymes degrade the virus permanently. A single abzyme molecule inactivates thousands of virus particles. Regular antibodies inactivate only one virus particle, and their anti-viral HIV effect is weaker. “HIV is an international priority because we have no defense against it,” Paul said. “Left unchecked, it will likely evolve into even more virulent forms. We have learned a lot from this research about how to induce the production of the protective abzymes on demand. This is the Holy Grail of HIV research -- development of a preventative HIV vaccine.” “The work of Dr. Paul’s group is highly innovative. They Continued on age 11 -10- Traditional African Clinic October 2008 Continued from page 10 – Pathologists believe they have pinpointed Achilles. Heel of HIV Major contributors to the research from the UT Medical School include Yasuhiro Nishiyama, Ph.D., and Hiroaki Taguchi, Ph.D., both with the Department of Pathology and Laboratory Medicine, and Miguel Escobar, M.D., of the Department of Pediatrics. Maria Salas and Hanson, both with the Viral and Rickettsial Disease Laboratory, contributed. The research was funded by the National Institutes of Health and the Texas Higher Education Coordinating Board. Journal references: Planque et al. Catalytic antibodies to HIV: Physiological role and potential clinical utility. Autoimmunity Reviews, 2008; 7 (6): 473 DOI: 10.1016/j.autrev.2008.04.002 Stephanie Planque et al. Catalytic antibodies to HIV: Physiological role and potential clinical utility. Autoimmunity Reviews, 2008; 7 (6): 473 DOI: 10.1016/j.autrev.2008.04.002 Adapted from materials provided by University of Texas Health Science Center at Houston. http://www.sciencedaily.com/releases/2008/07/080715165520. htm ☻☻☻☻☻☻ Continued from page 9 – WHO Murdered Africa laboratory, did they say it was "bad science" when that's exactly what occurred? As early as 1970 the World Health Organization was growing these deadly animal viruses in human tissue cultures. Cedric Mims, in 1981, said in a published article that there was a bovine virus contaminating the culture media of the WHO. Was this an accident or a "nonaccident"? If it was an accident why did WHO continue to use the vaccine? This viral and genetic death bomb, AIDS, was finally produced in 1974. It was given to monkeys and they died of pneumocystis carni which is typical of AIDS. Dr. R. J. Biggar said in Lancet. "...The AIDS agent... could not have originated de novo." That means in plain English that it didn't come out of thin air. AIDS was engineered in a laboratory by virologist. It couldn't engineer itself. As Doctor Strecker so colorfully puts it: "If a person has no arms or legs and shows up at a party in a tuxedo, how did he get dressed? Somebody dressed him." There are 9,000 to the fourth power possible AIDS viruses. (There are 9,000 base pairs on the genome.) So the fun has just begun. Some will cause brain rot similar to the sheep virus, some leukemia-like diseases from the cow virus and some that won't do anything. So the virus will be constantly changing and trying out new esoteric diseases on hapless man. We're only at the beginning. Because of the trillions of possible genetic combinations there will never be a vaccine. Even if they could develop a vaccine they would undoubtedly give us something equally bad as they did with the polio vaccine (cancer of the brain), the swine flu vaccine (a polio-like disease), the smallpox vaccine (AIDS), and the hepatitis vaccine (AIDS). There are precedents. This is not the first time the virologist have brought us disaster. SV-40 virus from monkey cell cultures contaminated polio cultures. Most people in their 40's are now carrying this virus through contaminated polio inoculations given in the early 60's. It is known to cause brain cancer which explains the increase in this disease that we have seen in the past ten years. This is the origin of the green monkey theory. The polio vaccine was grown on green monkey kidney cells. Sixtyfour million Americans were vaccinated with SV-40contaminated vaccine in the 60's. An increase in cancer of the brain, possibly multiple sclerosis, and God only knows what else the tragic result is. The delay between vaccination and the onset of cancer with this virus is as long as 20-30 years. 1965 plus 20 equals 1985. Get the picture? The final piece of the puzzle is how AIDS devastated the homosexual population in the United States. It wasn't from smallpox vaccination as in Africa because we don't do that any more. There is no smallpox in the United States and so vaccination was discontinued. Although some AIDS has been brought to the United States from Haiti by homosexuals, it would not be enough to explain the explosion of AIDS that occurred simultaneously with the African and Haitian epidemics. The AIDS virus didn't exist in the United States before 1978. You can check back in any hospital and no stored blood samples can be found anywhere that exhibits the AIDS virus before that date. What happened in 1978 and beyond to cause AIDS to burst upon the scene and devastate the homosexual segment of our population? It was the introduction of the hepatitis B vaccine which exhibits the exact epidemiology of AIDS. A Doctor W. Szmuness, born in Poland and educated in Russia, came to this country in 1969-Szmuness's immigration to the U.S. was probably the most fateful immigration in our history. He, by unexplained process, became head of the New York City blood bank. (How does a Russian trained doctor become head of one of the largest blood banks in the world? Doesn't that strike you as peculiar?) He set up the rules for the hepatitis vaccine studies. Only males between the ages of 20 and 40, who were not monogamous, would be allowed to participate in this study. Can you think of any reason for insisting that all experi- -11- Traditional African Clinic October 2008 Continued on page 12 Continued from page 11 – WHO Murdered Africa mentees be promiscuous? The Centers for Disease Control reported in 1981 that four percent of those receiving the hepatitis-vaccine were AIDS-infected. In 1984 they admitted to 60 percent. Now they refuse to give out figures at all because they don't want to admit that 100 percent of hepatitis vaccine receivers are infected with AIDS. Where is the data on the hepatitis vaccine studies? FDA? CDC? No, the U.S Department of Justice has it buried where you will never see it. What has the government told us about AIDS? * It's a homosexual disease-WRONG. (The homosexuals certainly spread it but the primary responsibility wasn't theirs.) * It's related to anal intercourse only-WRONG. * Only a small percentage of those testing positive for AIDS would get the disease-WRONG. * It came from the African green-back monkeyWRONG. * It came from the cytomegalovirus-WRONG. * It was due to popping amyl nitrate with sexWRONG. * It was started 400 years ago by the PortugueseWRONG. (It started in 1972.) * You can't get it from insects-WRONG. * The virus can't live outside the body-WRONG. The head of the Human Leukemia Research Group at Harvard is a veterinarian. Dr. O. W. Judd, International Agency for Research on Cancer, the agency that requested the production of the virus in the first place, is also a veterinarian. The leukemia research he is conducting is being done under the auspices of a school of veterinary medicine. Now there is nothing wrong with being a vet but, as we have pointed out, the AIDS virus is a human virus. You can't test viruses in animals and you can't test leukemias in them either. It doesn't work. So why would your government give Judd, a veterinarian, eight and one-half million dollars to study leukemia in a veterinary college? As long as we are being used as experimental animals, maybe it's appropriate. The London Times should be congratulated for uncovering the smallpox-AIDS connection. But their expose was very misleading. The article states that the African AIDS epidemic was caused by the smallpox vaccine "triggering" AIDS in those vaccinated. Dr. Robert Gallo, who has been mixed up in some very strange scientific snafus, supports this theory. Whether the infection of 75 million Africans was deliberate or accidental can be debated but there is no room for debate about whether the smallpox shots; "awakened the unsuspected virus infection." There is absolutely no scientific evidence that this laboratory-engineered virus was present in Africa before the World Health Organization descended upon these hapless people in 1967 with their deadly AIDS-laced vaccine. The AIDS virus didn't come from Africa. It came from Fort Detrick, Maryland, U.S.A. The situation is extremely desperate and the medical profession is too frightened and cowed (as usual) to take any action. Dr. Strecker attempted to mobilize the doctors through some of the most respected medical journals in the world. The prestigious Annals of Internal Medicine said that his material "appears to be entirely concerned with matters of virology" and so try some other publication. In his letter to The Annals, Strecker said, "If correct human experimental procedures had been followed we would not find half of the world stumbling off on the wrong path to the cure for AIDS with the other half of the world covering up the origination of the damned disease. It appears to me that your Annals of Internal Medicine is participating in the greatest fraud ever perpetrated." I guess they didn't like that so Strecker submitted his sensational and mind-boggling letter with all of the proper documentation to the British journal, Lancet. Their reply: "Thank you for that interesting letter on AIDS. I am sorry to have to report that we will not be able to publish it. We have no criticism" but their letter was "overcrowded with submissions." They're too crowded to announce the end of western civilization and possibly all mankind? It doesn't seem reasonable. What can we do? The first thing that should be done is close down all laboratories in this country that are dealing with these deadly retroviruses. Then we must sort out the insane irresponsible and traitorous scientists involved in these experiments and try them for murder. Then maybe, just maybe, we can re-staff the laboratories with people who will work to save a remnant of people to repopulate and re-civilize the world. References: 1. Allison, et al, Bull WHO 1972. 47:257-63 and Amos, et al. Fed Proc. 1972, 31:1087 2. Omni Magazine, March. 1986, p. 106. 3. Jan. 11, 1986. [???] 4. London Times Front page, May 11, 1987. http://healingtools.tripod.com/who_africa.html ☻☻☻☻☻☻ -12 - Traditional African Clinic October 2008 Continued from page 5 – Ancient African Medicine, Egypt and the World not changed their design since the ancient Africans first sent out this knowledge to the world. Today, researchers are still discovering “new” cures based on old Egyptian remedies, such as eating celery to help curb inflammation associated with arthritis. Roots of Kemitic Knowledge The study further conducted genetic and chemical analysis on plant remains and resins, with the goal of identifying trade routes, which species were used and how these plants might have been cultivated outside their natural growing ranges. After detailed facts gathering and analysis the scientists proposed that the African Egyptians obtained their medical knowledge from nomadic African tribes that united to form ancient Egypt, as well as from neighbouring African people in Kush and beyond. Current medical practices by the living African societies and traditions still show similarities to Pharaohic medicine. The continued use by African natural Doctors of medicinal herbs and animal products, and practices such as cosmetic dental filing, brain trepanning, orthopedic procedures, known to ancient Egyptians suggest sustained scientific and religious interaction in the past. Alas, current studies are revealing that the knowledge of medicine was transferred from central west Africa to Egypt, just like everything else that was gifted from Kush to Kemet. This is very significant since it is widely known that the foundations of modern western medicine came from Egypt. Around 50 percent of the plants used in ancient Egypt remained in clinical use. Medical tools like forceps, scissors and surgical blades, were lifted unchanged from ancient Egyptian medical science into modern western medicine. Medical practices, and knowledge of human anatomy, also found their way into the body of scientific knowledge underlying western medicine. Since the knowledge of Egyptian medical science was from inner Africa, more precisely central and western Africa, the world owes this continent and its children a belated tribute, a sound recognition for having bequeathed the science of healing and hygiene to later cultures and civilizations who still owe the unrequited debt of appreciation for Africa’s beneficence. Sources: http://www.eurekalert.org/pub_releases/2007-05/uomeng05090 .php http://dsc.discovery.com/news/2007/02/28/egyptiandrug_arc.html ?category=animals&guid=20070228104530 Chronicle of the Pharaohs (The Reign-By-Reign Record of the Rulers and Dynasties of Ancient Egypt) Clayton, Peter A. 1994 Thames and Hudson Ltd ISBN 0-500-05074-0. Complete Pyramids, The (Solving the Ancient Mysteries) Lehner, Mark 1997 Thames and Hudson, Ltd ISBN 0-500-05084-8. Dictionary of Ancient Egypt, The Shaw, Ian; Nicholson, Paul 1995 Harry N. Abrams, Inc., Publishers ISBN 0-8109-3225-3. History of Ancient Egypt, A Grimal, Nicolas 1988 Blackwell None Stated. Monarchs of the Nile Dodson, Aidan 1995 Rubicon Press ISBN 0-948695-20-x. Oxford History of Ancient Egypt, The Shaw, Ian 2000 Oxford University Press ISBN 0-19-815034-2. http://www.africaresource.com/content/view/559/236/ ☻☻☻☻☻☻ AIDS Epidemic hits Men Hard CDC: More than half of infections among gay and bisexual men in 2006 Reuters September 11, 2008 WASHINGTON - AIDS remains largely a disease of gay and bisexual men in the United States but also disproportionately infects black women, according to an analysis published on Thursday. Last month, the U.S. Centers for Disease Control and Prevention reported that more than 56,000 people in the United States become newly infected with the human immunodeficiency virus each year, far more than previous estimates of about 40,000. Now the CDC has further analyzed those numbers to find the fatal and incurable virus largely infects men who have sex with men, or MSM — a group that includes gays, bisexuals and men who may have the occasional sexual encounter other men. "The male-to-male sexual contact transmission category represented 72 percent of new infections among males, including 81 percent of new infections among whites, 63 percent among blacks, and 72 percent among Hispanics,” the report said. -13 - Traditional African Clinic October 2008 Continued on page 15 Threat of World Aids Pandemic among Heterosexuals is Over, Report Admits A 25-year health campaign was misplaced outside the continent of Africa. But the disease still kills more than all wars and conflicts By Jeremy Laurance 8 June 2008 The Independent A quarter of a century after the outbreak of Aids, the World Health Organisation (WHO) has accepted that the threat of a global heterosexual pandemic has disappeared. In the first official admission that the universal prevention strategy promoted by the major Aids organisations may have been misdirected, Kevin de Cock, the head of the WHO's department of HIV/Aids said there will be no generalised epidemic of Aids in the heterosexual population outside Africa. Dr De Cock, an epidemiologist who has spent much of his career leading the battle against the disease, said understanding of the threat posed by the virus had changed. Whereas once it was seen as a risk to populations everywhere, it was now recognised that, outside sub-Saharan Africa, it was confined to high-risk groups including men who have sex with men, injecting drug users, and sex workers and their clients. Dr De Cock said: "It is very unlikely there will be a heterosexual epidemic in other countries. Ten years ago a lot of people were saying there would be a generalised epidemic in Asia – China was the big worry with its huge population. That doesn't look likely. But we have to be careful. As an epidemiologist it is better to describe what we can measure. There could be small outbreaks in some areas." In 2006, the Global Fund for HIV, Malaria and Tuberculosis, which provides 20 per cent of all funding for Aids, warned that Russia was on the cusp of a catastrophe. An estimated 1 per cent of the population was infected, mainly through injecting drug use, the same level of infection as in South Africa in 1991 where the prevalence of the infection has since risen to 25 per cent. Dr De Cock said: "I think it is unlikely there will be extensive heterosexual spread in Russia. But clearly there will be some spread." Aids still kills more adults than all wars and conflicts combined, and is vastly bigger than current efforts to address it. A joint WHO/UN Aids report published this month showed that nearly three million people are now receiving anti-retroviral drugs in the developing world, but this is less than a third of the estimated 9.7 million people who need them. In all there were 33 million people living with HIV in 2007, 2.5 million people became newly infected and 2.1 million died of Aids. Aids organisations, including the WHO, UN Aids and the Global Fund, have come under attack for inflating estimates of the number of people infected, diverting funds from other health needs such as malaria, spending it on the wrong measures such as abstinence programmes rather than condoms, and failing to build up health systems. Dr De Cock labelled these the "four malignant arguments" undermining support for the global campaign against Aids, which still faced formidable challenges, despite the receding threat of a generalised epidemic beyond Africa. Any revision of the threat was liable to be seized on by those who rejected HIV as the cause of the disease, or who used the disease as a weapon to stigmatise high risk groups, he said. "Aids still remain the leading infectious disease challenge in public health. It is an acute infection but a chronic disease. It is for the very, very long haul. People are backing off, saying it is taking care of itself. It is not." Critics of the global Aids strategy complain that vast sums are being spent educating people about the disease who are not at risk, when a far bigger impact could be achieved by targeting high-risk groups and focusing on interventions known to work, such as circumcision, which cuts the risk of infection by 60 per cent, and reducing the number of sexual partners. There were "elements of truth" in the criticism, Dr De Cock said. "You will not do much about Aids in London by spending the funds in schools. You need to go where transmission is occurring. It is true that countries have not always been good at that." But he rejected an argument put in The New York Times that only $30m (£15m) had been spent on safe water projects, far less than on Aids, despite knowledge of the risks that contaminated water pose. "It sounds a good argument. But where is the scandal? That less than a third of Aids patients are being treated – or that we have never resolved the safe water scandal?" One of the danger areas for the Aids strategy was among men who had sex with men. He said: "We face a bit of a crisis [in this area]. In the industrialised world transmission of HIV among men who have sex with men is not declining and in some places has increased. -14- Traditional African Clinic October 2008 Continue on page 15 Continued from page 14 – Threat of World HIV Pandemic Among Heterosexuals is Over "In the developing world, it has been neglected. We have only recently started looking for it and when we look, we find it. And when we examine HIV rates we find they are high. "It is astonishing how badly we have done with men who have sex with men. It is something that is going to have to be discussed much more rigorously." The biggest puzzle was what had caused heterosexual spread of the disease in sub-Saharan Africa – with infection rates exceeding 40 per cent of adults in Swaziland, the worst-affected country – but nowhere else. "It is the question we are asked most often – why is the situation so bad in sub-Saharan Africa? It is a combination of factors – more commercial sex workers, more ulcerative sexually transmitted diseases, a young population and concurrent sexual partnerships." "Sexual behaviour is obviously important but it doesn't seem to explain [all] the differences between populations. Even if the total number of sexual partners [in subSaharan Africa] is no greater than in the UK, there seems to be a higher frequency of overlapping sexual partnerships creating sexual networks that, from an epidemiological point of view, are more efficient at spreading infection." Low rates of circumcision, which is protective, and high rates of genital herpes, which causes ulcers on the genitals through which the virus can enter the body, also contributed to Africa's heterosexual epidemic. But the factors driving HIV were still not fully understood, he said. "The impact of HIV is so heterogeneous. In the US , the rate of infection among men in Washington DC is well over 100 times higher than in North Dakota, the region with the lowest rate. That is in one country. How do you explain such differences?" http://www.independent.co.uk/life-style/health ☻☻☻☻☻☻ Continued from page 13 - Aids Epidemic Hits Men Hard Of the new infections in 2006, more than half were among gay and bisexual men, the CDC found. Of these, 46 percent of new infections were among whites, 35 percent among blacks and 19 percent in Hispanics. But among the overall U.S. population, more blacks are affected — 46 percent of new infections were among blacks. especially in the black community. "The alarming number of new infections among young black MSM underscores the need to ensure that each new generation has the knowledge and skills to prevent HIV infection beginning early in their lives," the report reads. Girls and women made up 27 percent of new infections, with high-risk sexual contact with men causing 80 percent of new infections. "Among females, 61 percent of infections were in blacks, 23 percent were in whites, and 16 percent were in Hispanics," the CDC report reads. There is no cure for the AIDS virus, which is transmitted in bodily fluids such as blood, semen and breast milk. Around the world, sexual contact is by far the most common mode of transmission although people who use contaminated needles can be infected, and blood transfusions also can cause infection. "African-Americans make up 12 percent of the total U.S. population, yet represented 45 percent of new HIV infections in the United States in 2006," the CDC wrote. Globally, 33 million people are infected with HIV and 25 million have died of it. There is no vaccine or cure although drug cocktails can help control the infection. URL: http://www.msnbc.msn.com/id/26660893/ ☻☻☻☻☻☻ Common Gene makes Africans more Vulnerable to HIV James Randerson Guardian.co.uk July 17, 2008 Around 11% of HIV infections in Africa may be due to a genetic variant common in people of African descent that makes them more vulnerable to the virus. The genetic change, which is less prevalent in other ethnic groups, increases the likelihood of infection with the most com mon strain of the virus (HIV-1) by 40%. Once infection has occurred, though, the genetic variant slows the progression of the disease, prolonging the patient's life by around two years. The newly discovered genetic factor may go some way to explaining why AIDS is so prevalent in sub-Saharan Africa. According to the World Health Organisation, there were 4.3 million people newly infected with HIV worldwide in 2006 and 2.9 million deaths from AIDSrelated illnesses. Around a third of all new infections and The CDC said it needed to redouble prevention efforts, -15- Traditional African Clinic October 2008 Continued on page 17 African Traditional Herbal Research Clinic Volume 3, Issue 9 NEWSLETTER October 2008 FEATURED ARTICLES “What are Duffy Antigens?” An antigen is a molecule that will set off the forces of the immune system to get rid of things that may be bad for us. Scientists are just starting to realize that the antigen molecules that distinguish one blood type from another have a lot of other important jobs elsewhere in our bodies. Here's how it works. All our cells have numerous molecules on the surface that, like little billboards, announce, `This cell is part of us. It's supposed to be here. Do not attack!' Immune system cells traveling around in our blood are trained to recognize self molecules and pass right by. But if our immune system inspects a foreign cell in our blood and doesn't recognize a molecule on the surface, it treats that molecule as an antigen and attacks. That attack often involves creating a molecule called an antibody designed specifically to fit the unique shape of the foreign antigen. The antibody attaches to the antigen and, like a chemical loudspeaker, summons other components of the immune system to come destroy the invader. In 1901 Karl Landsteiner of Austria noticed that some red blood cells had one kind of molecule on their outer surface, which he labeled simply A, and some had a different one that he labeled B. Some didn't have either, and he called those O (as in zero, not the letter ``o''.) Those molecules turned out to be antigens. The discovery made transfusions possible and earned Landsteiner a Nobel prize. Since then, we've discovered nearly 300 different antigens on red blood cells, with names like Duffy, Lutheran, Dombrock, Kidd, Diego, P, Yt, and Kx. They're mostly named for the people whose blood carried unique antibodies. Like Mr. Duffy, the English patient who got sick after a transfusion. He received the right ABO type. But there was another antigen on the transfused blood that his immune system didn't like. It made a special antibody cell nobody had ever seen before to fit onto and attack that antigen. That antigen was named Duffy. In 1950, the Duffy blood group was named for the multiply transfused hemophiliac whose serum contained the first example of anti-Fya. In 1951, the antibody to the antithetical antigen, Fyb, was discovered in the serum of a woman who had been pregnant three times. Using these antibodies three common phenotypes were defined: Fy(a+b+), Fy(a+b-), and Fy(a-b+). Differences in the racial distribution of the Duffy antigens were discovered four years later when it was reported that the majority of Blacks had the erythrocyte phenotype Fy(a-b-). This phenotype is exceedingly rare in Whites. The frequency of the Fy(ab-) phenotype is 68 percent in American Blacks and 88100 percent in African Blacks. The absence of Duffy antigens on erythrocytes results in their resistance to invasion by two malaria parasites, Plasmodium vivax and Plasmodium knowlesi. This racial variation in distribution of the Duffy system antigens provides one of the few known examples of selective advantage conferred by a blood group phenotype. The Duffy genes, located on chromosome one at position 1922-23, have recently been cloned and sequenced. The difference between Fya and Fyb is a change in the amino acid at position 43 from aspartic acid (Fya) to glycine (Fyb). Studies have shown that blacks whose erythrocytes express Fyb antigen also have the antigen on the cells of their kidney, heart, muscle, brain and placenta. The Duffy gene codes for a protein known as a chemokine receptor, which is important in the inflammatory process. Rh is another well-known red blood cell antigen. Rhesus monkeys experimentally transfused with human blood made the antibody this time, thus the Rh. If you have this antigen (there are actually 40 antigens in the Rh family) you're Rh positive. If you don't, you're Rh negative. Rh and ABO antigens are the most important ones determining whether a transfusion will work. But nature didn't put antigens on our red blood cells to make sure transfusions would work. Transfusions are not a natural occurrence. So what's going on? -16- Traditional African Clinic October 2008 Continued on page 17 Continued from page 17 – “What are Duffy Antigens” It turns out that these molecules are involved in many other biological processes. Remember Duffy? Well, many Africans and AfricanAmericans don't have a Duffy antigen. As a result, they can survive a form of malaria that infects the cell only if it can attach to Duffy. No Duffy antigen, no P. vivax malaria. Remember the P antigen? One species of E. coli bacteria needs that molecule to attach to tissue cells in the urinary tracts of children. Some children have that molecule. Some don't. Those without it don't get that kind of urinary infection. The molecule that the bacterium H. pylori attaches to in the stomach lining to cause ulcers is an antigen when it's on red blood cells. On some non-blood cells, antigens appear, or disappear, or change, as tumors go from benign to cancerous. Some antigen molecules appear to play a role in helping cancer spread through the body. Some help blood cell membranes maintain their shape. Some help cells process proteins. Statistical associations, which don’t automatically prove cause and effect, show that A's have more cancers than O's and that O's bleed more than A's. B's defecate the most. O's have the best teeth, but suffer more than other blood types from plague infections. A's have the worst hangovers. There are wide racial, ethnic, and geographic differences in blood types around the world. There are twice as many O's among native Australians as among Japanese. Eskimos in Greenland are 25 times more likely to be B's than Navajos in North America. Citizens of India are four times more likely to be B's than residents of England. All the findings suggest that molecules that distinguish blood types probably developed differently in different people as part of the random processes of mutation and evolution. As nature tests which ones are best, some will offer advantages, some disadvantages, in ways that immuno-hematologists like Garratty are only beginning to understand. http://jove.prohosting.com/~scarfex/blood/8.html http://www.boston.com/globe/search/stories/health/how_and_w hy/112398.htm ☻☻☻☻☻☻ Scientists make Gene Link to African HIV Epidemic Mark Henderson, Science Editor From The Times July 17, 2008 A genetic variant peculiar to Africans substantially raises their risk of infection with HIV, according to research that suggests evolved susceptibility may be helping to drive the continent’s Aids epidemic. The 90 per cent of Africans who carry the DNA variation are 40 per cent more likely to contract HIV than those without it, after similar exposure to the virus, scientists from Britain and America have found. As the genetic change is common among people of African ancestry but virtually unknown among other ethnic groups, it could explain in part why HIV-Aids is more prevalent in sub-Saharan Africa. The United Nations estimates that 22.5 million people there are HIVpositive, more than two thirds of the global total of approximately 33.2 million. The variant, known as “Duffy-negative”, is so common in Africa that it could be responsible for about 11 per cent of the continent’s HIV burden, or 2.5 million cases, scientists said. “It is an Africa-specific variant, which is why it’s so interesting in the context of Aids research,” said Robin Weiss, Professor of Infection and Immunity at University College London, a member of the study team. “It could certainly be a contributing factor to the scale of the epidemic in sub-Saharan Africa. It’s the first time, so far as we understand, that a genetic factor that increases susceptibility to infection has come into play.” Sexual behaviour is also involved in the epidemic in Africa, the only part of the world in which it predominantly affects heterosexuals. The Duffy-negative gene has probably spread so widely through the African population because it provides resistance to a form of malaria called Plasmodium vivax. Professor Weiss believes it may also once have increased resistance against a precursor of the most deadly malaria parasite, Plasmodium falciparum. These traits would have been highly advantageous in evolutionary Africa. As HIV is a new human pathogen, thought to have jumped from chimpanzees to people between 1910 and 1950, the gene’s effect on the virus would have had no negative consequences until recently. Continued on page 18 -17- Traditional African Clinic October 2008 Continued from page 18 – Scientists make Gene Link to African HI Epidemic “Something that protected against malaria in the past is now leaving the host more susceptible to HIV,” Professor Weiss said. Matthew Dolan, of the San Antonio Military Medical Centre in Texas, said: “After thousands of years of adaptation, this Duffy variant rose to high frequency because it helped protect against malaria. Now, with another global pandemic on the scene, this same variant renders people more susceptible to HIV. It shows the complex interplay between historically important diseases and susceptibility in contemporary times.” For the study, published in the journal Cell Host & Microbe, scientists examined a group of US Air Force personnel, of whom more than 1,200 are HIV-positive, and who have been followed for nearly 22 years. The Duffy-negative genotype was seen almost exclusively in African-Americans. A continent cursed — Sub-Saharan Africa is the globe’s most Aids-affected region. In 2005, 24.5 million of its people were living with HIV and of all Aids sufferers, 64 per cent live there — In 2005, about 2.7 million people became infected with HIV and more than two million died — More than two million children under 15 are HIVpositive and more than 90 per cent live in Africa — About 12 million African children under 17 have lost one or both parents to Aids — About 72 per cent of all people needing anti-retroviral treatment live in Africa, and only one in six receives the necessary medicine is complicated because the disease has developed resistance to the most commonly used treatments. A survey comprising of Semi-Structured Interviews and a questionnaire was undertaken in the rural villages of Buseete and Busambira found in Kamuli district, Uganda, to document herbal medicines used in the treatment of malaria and to document existing knowledge, attitudes and practices related to malaria recognition, control and treatment. The people were knowledgeable about malaria. Malaria attacked individuals an average of six times a year. Conditions favoring the breeding of mosquitoes, such as dense bush, were evident in all homesteads. Preferred malaria treatment was biased towards the Allopathic Medicine (AM) system. This preference for AM was attributed to ignorance of how to exploit herbal medicines for the treatment of malaria and also to the belief that allopathic medicines were superior to herbal medicines. Some respondents stated a preference to herbal medicines, though. This preference was motivated by the free and ready accessibility to plants. Knowledge of using herbal medicines was average and was mainly restricted to women. Twenty seven species were reportedly used in antimalarial herbal preparations. The most frequently mentioned species were Vernonia amygdalina, Momordica foetida, Zanthoxylum chalybeum, Lantana camara and Mangifera indica. Concoctions were prepared as cold extracts and were administered in variable doses. It is proposed that the most frequently mentioned species be considered for further research to evaluate their efficacy and safety. http://www.wlbcenter.org/drawer/reports/final_report.pdf ☻☻☻☻☻☻ — Swaziland has the highest HIV rate, at 33.4 per cent of population. Botswana has 24.1 per cent and Zimbabwe 20.1 per cent Source: UNAids 9 Million Children Worldwide Died Before Age 5 http://www.timesonline.co.uk/tol/life_and_style/health/article4 345263.ece ☻☻☻☻☻☻ Rate of under-five mortality dipped slightly from 2006, UNICEF says Herbal Medicines for the Treatment of Malaria in Kamuli District, Uganda John R.S. Tabuti Makerere University, Kampala, Uganda Abstract Malaria is the single most important cause of ill health, death and poverty in Sub-Saharan Africa. Its management Reuters September 11, 2008 LONDON - More than 9 million children globally died before their fifth birthday in 2007, down slightly from 2006, but a huge gap remains between rich and poor countries, especially in Africa, UNICEF said on Friday. Efforts to promote breastfeeding, immunizations and anti-malaria measures have helped cut child deaths to 9.2 million from 9.7 million a year ago and 12.7 million in 1990, the figures from the United Nations Children’s Fund showed. Continued on page 19 -18- Traditional African Clinic October 2008 Continued from page 18 – 9 Million Children Worldwide Died Before Age 5 “Since 1960, the global under-five mortality rate has declined more than 60 percent, and the new data shows the downward trend continues,” UNICEF Executive Director Ann Veneman said in a statement. Improvements in Latin America and the Caribbean, Central and Eastern Europe, the former Soviet Union and in parts of Asia drove the overall decline, but deaths remain high in sub-Saharan Africa where one in seven children dies before age 5. AIDS is still a major killer of children in sub-Saharan Africa, though countries such as Eritrea, Malawi, Mozambique, Niger and Ethiopia have made significant progress in cutting mortality rates, UNICEF said. “Sub-Saharan Africa now accounts for almost half of the 9.2 million deaths among children in this age group annually,” according to the UNICEF report published in the journal Lancet. “High levels of fertility...together with high levels of mortality in children aged less than 5 years have led to an increase in the absolute number of deaths (in this region).” Worldwide, the death rate for children under age 5 was 68 per 1,000 live births in 2007, down from the 93 per 1,000 in 1990 and 72 per 1,000 a year ago. Sierra Leone had the worst under-five mortality rate in the world with 262 out of every 1,000 children dying before their fifth birthday. The rate in industrialized nations was 6 per 1,000. A number of countries, including Laos, Bangladesh, Bolivia and Nepal, have also made good progress toward meeting global targets to reduce the child mortality rates by two-thirds between 1990 and 2015, UNICEF said. “Recent data also indicate encouraging improvements in many of the basic health interventions, such as early and exclusive breast feeding, measles immunization, Vitamin A supplementation, the use of insecticide-treated nets to prevent malaria, and prevention and treatment of AIDS,” Veneman said. “These interventions are expected to result in further declines in child mortality over the coming years.” URL: http://www.msnbc.msn.com/id/26665596/ ☻☻☻☻☻☻ ☻☻☻☻☻☻ Malaria Drug ‘Contributing to Antibiotic Resistance’ SciDev.Net Daily Monitor August 3, 2008 A new study shows that overuse of a drug used to prevent and treat malaria may be contributing to growing resistance to a related antibiotic. Researchers report in the journal PloS ONE that Escherichia coli bacteria resistant to the antibiotic ciprofloxacin – a type of fluroquinolone – were detected in the digestive tracts of villagers from remote rainforest communities in Guyana, despite them never having been given the drug. Most of the villagers had been given the drug chloroquine – a drug closely related to ciprofloxacin – to prevent and treat malaria. 535 villagers were sampled for resistant bacteria in the three-year study, with 4.8 per cent found to be carrying ciprofloxacin-resistant E. coli. Guyana recorded over 11,000 cases of malaria last year, the Minister of Health, Dr. Leslie Ramsammy, told SciDev.Net. He said the findings were “interesting” and that the Ministry of Health would commission its own study to test the accuracy of the research results. The antibiotic ciprofloxacin is used throughout the world to treat bacterial infections, including pneumonia, urinary tract infections and sexually transmitted diseases. This is the first study to show that resistance can emerge in individuals never exposed to the antibiotic. Drug resistant bacteria are known to arise from overuse of antibiotics, which is why researchers were surprised to discover that they can develop in areas that do not have access to ciprofloxacin, says study co author Michael Silverman, an infectious disease specialist at Lakeridge Health Network in Ontario, Canada. In fact, he says, ciprofloxacin-resistant E. coli were even more widespread in remote Guyanese villages than in the United States intensive care units “where every second person is on antibiotics”. E. coli is one of the most common causes of infection in humans. A decade ago it was nearly universally susceptible to ciprofloxacin,” says Andrew Simor, a senior scientist at the Sunnybrooke Health sciences Center at the University of Toronto. Today, he says, as many as 30 per cent of hospital patients tested have E. coli that fails to respond to ciprofloxacin. Continued on page 20 -19- Traditional African Clinic October 2008 Continued from page 19 – Malaria Drug Contributing to Antibiotic Resistance Resistance to ciprofloxacin could be an important public health problem in areas where malaria is endemic - and therefore chloroquine use common – because ciprofloxacin and other fluroquinolones could be less effective, write the authors. Silverman stressed that the study highlights the need to continue to try to prevent malaria through the use of insecticide-treated bed nets, along with the development of an effective vaccine. ☻☻☻☻☻☻ Malaria Fuels HIV/Aids Spread In Africa By Will Dunham December 8, 2006 malaria has helped HIV infect hundreds of thousands and perhaps millions of people in sub-Saharan Africa. AIDS was first identified a quarter century ago. At the same time, HIV fuels malaria's spread because HIV-infected people are more susceptible to malaria as a result of HIV ravaging the immune system, the body's natural defenses, the researchers said. AIDS and malaria are concentrated in sub-Saharan Africa. Abu-Raddad said scientists were puzzled when they realized that the risky sexual behavior by people in the region was not by itself sufficient to explain the swift spread of HIV, so other factors must be involved. They focused their work on Kisumu, a Kenyan city by Lake Victoria where HIV and malaria are both common. They said 5 percent of HIV infections can be blamed on the increased HIV viral load due to malaria, and 10 percent of adult malaria cases can be blamed on HIV. Note - What the story ISN'T saying is that mosquitoes are SPREADING HIV. Every time a mosquito or ANY biting insect takes blood from an infected human and then bites the next person, scores of viruses and bacteria are transmitted. To write a news story without pointing to the obvious disease-vectoring reality of mosquitoes is gross deception at the least. This is a particularly odious statement: "Higher viral load causes more HIV transmission, and malaria causes high HIV viral load.” Mosquitoes are already KNOWN to transmit over 70 different retroviruses. HIV is a retrovirus...but there is no mention of any of this in the following story. - ed Since 1980, 8,500 more people got HIV infections, and there were 980,000 more episodes of malaria (a person can get it more than once) in a city whose adult population is 200,000, the study found. WASHINGTON (Reuters) - Malaria may be helping spread the AIDS virus across Africa, the continent hardest hit by the incurable disease, scientists said on Thursday. Malaria kills more than a million people annually, mostly young children in sub-Saharan Africa. The way the two diseases interact greatly expands the prevalence of both among people in sub-Saharan Africa, a team of scientists said in a study in the journal Science. Malaria, a mosquito-borne disease caused by a parasite, greatly boosts viral load -- the amount of human immunodeficiency virus in the blood of infected people -- making them more likely to infect a sex partner with HIV, they stated. "Higher viral load causes more HIV transmission, and malaria causes high HIV viral load," said lead study author Laith Abu-Raddad of the Fred Hutchinson Cancer Research Center in Seattle and the University of Washington. PUBLIC HEALTH EFFORTS The findings have implications for public health efforts, Abu-Raddad said, showing the importance for authorities to tackle these diseases together. Of the 39.5 million people worldwide infected with HIV, 24.7 are in the poor countries of sub-Saharan Africa. About 2.1 million of the world's 2.9 million AIDS deaths in the past year were in this region. The researchers produced their results with a mathematical model using HIV and malaria infection data gathered in Malawi by James Kublin of the Hutchinson Center. This enabled them to quantify for the first time the synergy between malaria on HIV and its toll on people. Scientists previously determined that a lack of male circumcision and the incidence of genital herpes also were facilitating the spread of HIV. Abu-Raddad noted that circumcised men are much less likely to get HIV, and that genital herpes opens a door for HIV to infect a person. Abu-Raddad said malaria now can be considered a third serious factor facilitating the spread of HIV. The two diseases drive one another even though they have different modes of transmission-- malaria by mos- Abu-Raddad, an AIDS researcher, estimated that -20- Traditional African Clinic October 2008 Continued on page 21 Continued from page 20 – Malaria Fuels HIV Spread in Africa quito and HIV predominantly by sexual intercourse, Abu-Raddad noted. Abu-Raddad said once an HIV person gets malaria, his or her viral load goes up and stays higher for six to eight weeks, making the person far more infectious to others. http://www.rense.com/general74/mala.htm ☻☻☻☻☻☻ Continued from page 15 - Common Gene Makes Africans More Vulnerable to HIV AIDS- related deaths occur in sub-Saharan Africa, where there are eight countries in which adult HIV prevalence exceeds 15% of the population. Ironically, scientists believe that the genetic variant is at such high levels in Africa because it conferred resistance to a now extinct form of malaria. A team of British and US researchers studied a group of 3,484 people in the US Air Force, of whom 1,266 were infected with HIV. They tested each for a gene variant called Duffy Antigen Receptor for Chemokines (DARC), which has been extensively studied in the past because of its ability to confer resistance to one form of the malaria parasite. The gene is known to be common among people of African descent. The team report in the journal Cell, Host and Microbe that subjects who were DARC-negative were more likely to be infected with HIV. The gene variant appeared to make them 40% more susceptible to infection. By extrapolating this figure to the number of people in Africa with the same genetic variation, the researchers estimate that 11% of all HIV infections in the continent are due to this increased susceptibility. "The mystery of variable infection and progression was originally thought to be mainly the result of viral characteristics, but in recent years it has become evident that there is a strong host genetic component," said team member Dr Sunil Ahuja of the University of Texas Health Science Center in San Antonio. "The big message of this paper is that something that protected people against malaria in the past is now leaving them more susceptible to HIV," said Robin Weiss of University College London, who also worked on the study. http://www.guardian.co.uk/science/2008/jul/17/hiv.aids/ ☻☻☻☻☻☻ Scientists Map Genomes of Malaria Parasites Discovery will help in creating new treatments, vaccines, researchers say Reuters October 8, 2008 WASHINGTON - Scientists have mapped the genomes of the parasite that causes most cases of malaria outside Africa and a monkey parasite that is emerging as an important cause of malaria in people in Southeast Asia. This information should help guide efforts to develop new drugs and vaccines to fight the mosquito-borne disease, two teams of researchers wrote in the journal Nature on Wednesday. "It's going to be a very powerful tool," Jane Carlton of New York University Langone Medical Center said. A team led by Carlton worked out the complete genetic sequence of the parasite Plasmodium vivax, which causes malaria in Latin America and Asian countries including India, Thailand, Vietnam, Indonesia, Melanesia and the Korean peninsula. It accounts for up to 40 percent of malaria globally, with an estimated 2.6 billion people threatened by the parasite. Although the malaria it causes is only occasionally fatal, it triggers severe symptoms such as repeated episodes of high fever followed by headache, chills and profuse sweating, vomiting, diarrhea and enlargement of the spleen. The vivax parasite can remain dormant in the liver only to re-emerge and cause relapses months or years after the initial illness. The researchers found genes that may be responsible for this dormancy, perhaps paving the way for scientists to find ways to disrupt it. The researchers identified genes in the parasite that seem to help it invade a person's red blood cells and evade the immune system. The parasite is becoming resistant to some antimalarial drugs. A team led by Arnab Pain of the Wellcome Trust Sanger Institute in Britain deciphered the full genetic sequence of the monkey parasite Plasmodium knowlesi. This parasite is rapidly establishing itself as the fifth human-infecting malaria parasite and has emerged as a considerable health problem in Southeast Asia, Pain said. The researchers also found a trick used by the knowlesi parasite to avoid detection by the immune system. Continued on page 32 -21- Traditional African Clinic October 2008 Malaria Builds Resistance, Kills Millions GLENN McKENZIE Associated Press September 20, 2003 LAGOS, Nigeria - Malaria, the ancient mosquito-borne disease that was rolled back by medical advances in the mid-20th century, is making a deadly comeback. Strains of the disease are becoming increasingly resistant to treatment, infecting and killing more people than ever before - sickening as many as 900 million last year, according to estimates by the U.S. Agency for International Development. The Bill and Melinda Gates Foundation, which has supported malaria efforts, is also expected to announce new funding toward malaria medicines, controls and vaccine research this weekend. "We hope that malaria gets some additional visibility," Bill Gates, the Microsoft tycoon, said in a conference call with journalists. "Of those million people who die, overwhelmingly those are children. ... This is something we should demand more action on." Malaria campaigners complain that despite the increased focus, their efforts remain woefully underfunded. Whereas AIDS vaccine research receives $400 million a year, malaria research receives just $60 million. More than 1 million people - and as many as 2.7 million by some estimates - of those victims died. The vast majority of the deaths were in Africa. While donors commit an estimated $200 million each year to treating impoverished patients and distributing mosquito nets and insecticides to prevent mosquito bites that transmit the disease, experts say they need at least $1 billion to make a dent. Shivering and sweating feverishly, Felicia Egbuchue took the malaria medicine her doctor prescribed. Although it had cured her in years past, this time it didn't. She was rushed to the hospital, and hooked up to an intravenous drip. "Malaria has to some extent been forgotten by the international community," said Allan Schapira, a senior official in WHO's Rollback Malaria program. "Apart from AIDS, it is the single worst child health problem that we haven't got a grip on." "I have no inner strength. I feel like I'm dying," the 30year-old university student said from her hospital bed. In Nigeria, a nation of 126 million people where government officials estimate up to one-quarter of the world's malaria deaths occur, researchers at the national Nigerian Institute of Medical Research test malaria treatments and other drugs on mice in a single tiny, stiflingly hot laboratory. After three days in a private hospital in Nigeria's commercial capital of Lagos, Egbuchue recovered from what doctors said was a strain that had become resistant to many of the standard treatments. "Malaria is something that we thought we had conquered years ago. But more and more of our people are dying from it every day," said Patrick Dike, a malaria specialist at the Lagos hospital. Only AIDS kills more people worldwide. Among child ren, malaria kills even more than AIDS. The economic cost of malaria is also high - in countries of Africa, Asia and Latin America where the disease is endemic, the World Health Organization estimates up to $12 billion are lost annually to the disease. Americans traveling abroad also are at risk. Of the 225 Marines and Navy forces who went ashore to assist West African peacekeepers in Liberia, 51 showed symptoms - an unusually high rate, U.S. officials said. International efforts to contain or even eradicate the disease have received a boost in recent years with major grants from the U.S. government and from the $4.7 billion five-year U.N. Global Fund for Aids, Tuberculosis and Malaria. "The resources available in Nigeria for this work are limited or even nonexistent," research director Philip Agomo said. A major cause of malaria's alarming resurgence is the parasite's increasing resistance to the drugs used to treat and prevent the disease - including chloroquine, the cheapest and most effective anti-malarial since the 1950s. The number of alternatives are limited. The WHO supports use of multi-drug combinations based on artemisinin, until recently an extract from the "sweet wormwood" plant used in China for centuries but little known in the West. Yet aid agency officials say that artemisinin is not yet produced in large enough quantities to affordably treat the large numbers of Africans who need it most. Some governments and Western donors have been hesitant to promote the treatment widely because of a lack of funds - artemisinin is 10 times more expensive than chloroquine, or between $4.50 and $9 for a threeday treatment. Continued on page 23 -22- Traditional African Clinic October 2008 Continued from page 22 – Malaria Builds Resistance malaria drugs. "It is definitely the future," Anne Peterson, head of global health for USAID in Washington, said of artemisinin-based drugs. "Yet it is far more expensive and harder to get out to the numbers of people who need it." A team of French and Cameroonian scientists made the discovery after collecting samples of Anopheles mosquitoes from five localities including Oveng village -- which lies between two rivers near the border with Gabon and Equatorial Guinea. The Nobel Prize-winning international humanitarian group Medecins Sans Frontieres is urging the United States and other Western governments to support and fund artemisinin-based therapy regimens. It notes chloroquine and other drugs have become ineffective in up to 80 percent of malaria cases in some countries. "It is then that we discovered that the samples from Oveng village were different from existing varieties in terms of morphology and behaviour," Parfait Herman Awono-Ambene, one of the scientists who carried out the research, told Reuters on Friday. "Donors must stop wasting their money funding drugs that don't work," MSF said in a report. Peterson, the USAID official, said that until it receives more funds, the U.S. agency will support the use of the "cheapest, most effective drugs" in countries where they still have use. Dike, the Lagos doctor, said in the absence of affordable alternatives, he and some colleagues have in desperation begun exchanging information about what available combinations work best to treat patients. "People don't understand why their relatives are sometimes not recovering, or why they are not being cured as quickly as they are used to being cured. How do you explain drug resistance? When they are suffering, the doctor is blamed." http://www.miami.com/mld/miamiherald/6820492.htm ☻☻☻☻☻☻ Mosquitoes from the Anopheles group transmit malaria -- which kills roughly 3,000 people every day -- to humans along rivers in Africa. The results of the study were published in the July issue of the Journal of Medical Entomology. "The interesting thing about Oveng Form is that it is hardly found inside houses though it bites human beings just like others and contains the malaria-carrying agent Plasmodium falciparum," Awono-Ambene said, referring to the most life-threatening form of the disease. He said the mosquito found in Oveng becomes very active at dusk, feeding on people who live near or along the banks of the two rivers. More research will need to be carried out to determine whether this variety is only present in Oveng village, but Awono-Ambene said the mosquito was also likely to exist in neighbouring Gabon and Equatorial Guinea. New Malaria-Carrying Mosquito Found in Cameroon Malaria costs Africa around $12 billion a year in lost income. By Tansa Musa The country's public health authorities are promoting the use of impregnated nets to fight the disease, but adequate nets are not always easily available and at 3,500 CFA francs ($6.5) they are often too expensive for the average household. 24 July 2004 YAOUNDE, July 24 (Reuters) - A new form of mosquito carrying the parasite responsible for the most deadly form of malaria, Africa's biggest killer alongside HIV/AIDS, has been discovered in a village in southern Cameroon, researchers say. In Cameroon, it represents 35 to 40 percent of deaths in hospitals and is responsible for 40 percent of deaths among children aged between zero and five. http://www.alertnet.org/thenews/newsdesk/L24594997.htm ☻☻☻☻☻☻ FYI – In Uganda Discovery of the hitherto-unknown variety, provisionally dubbed "Oveng Form" after the village where it was found, is likely to make the fight against the malaria in Cameroon even more difficult, researchers say, although more research is needed. 25-40 Percent of outpatients visit health centres due to Malaria. It joins four other species already known in the central African country, all of them resistant to common anti- Malaria is the leading cause of death in Uganda. 20 Percent of hospital admissions and 15 per cent of in-patients deaths are due to Malaria. -23- Traditional African Clinic October 2008 ☻☻☻☻☻☻ Scientists say Africa Must Make Own Drugs to Fight AIDS, Malaria treatment in the area of enforced HIV illness. And the letter has been sent to one of the prominent figure within the African community. We will appreciate if you can pass on this letter to other African people within the community. By ELLIOTT SYLVESTER I believe that the human and health rights of Africans in New Zealand are being severely transgressed in the testing, diagnosis and treatment (especially when enforced) of HIV disease. This discrimination is manifest in several forms. Associated Press March 20, 2003 STELLENBOSCH, South Africa - Scientists challenged African nations Thursday to produce their own generic drugs - not just rely on pharmaceutical giants to help fight AIDS, malaria and other diseases ravaging the continent. African nations lag behind countries such as Cuba and India that produce "homegrown" medicines, Gordon Dougan, a British vaccine expert, told a conference on the human genome initiative. "We need to reinvent local production of high quality generic vaccines," Dougan said. "Countries are no longer producing their own vaccines, and this is why huge pharmaceutical companies control the industry." More than 300 scientists from 16 countries are in Stellenbosch, about 30 miles north of Cape Town, at a conference aimed at using knowledge of the human genome - a genetic blueprint that scientists are working to map - to help combat diseases. Dr. Hoosen Coovadia, HIV/AIDS researcher at South Africa's University of Natal, said African governments should translate scientific research into policy to overcome the most serious diseases facing Africa. The United Nations estimates there were 3.4 million new HIV infections in Africa in 2001 - almost 70 percent of the global total. British Dr. Matt Berriman told the conference human genome research has cut the time it is taking him to find a vaccine for malaria - a vaccine he said may ready for use in 20 years. The mosquito-borne disease kills about 3,000 Africans a day, most of them under five years of age. ☻☻☻☻☻☻ To all African People Living in New Zealand March 1, 2008 This letter is to let all African people living in New Zealand about the discrimination that is happening here in New Zealand in regard to the testing, diagnosis and Simply being Black African in New Zealand is seen as “high risk” compared to being tested in African countries. This is an important consideration in relation to interpretation of the tests (because the interpretation is arbitrary). The staff deciding the test results are informed in their own 2000 handbook: “By mid 1999, 1,355 patients had been reported with HIV infection since the beginning of the epidemic and 678 with AIDS. Currently there are about 700 HIV infected people living in New Zealand of whom 107 have AIDS. Homosexual males remain the biggest identifiable risk group (63% now) but in the last 18 months infected heterosexual immigrants, particularly from Africa, are the most rapidly increasing group. After falling for several years, the number of newly reported HIV infected people rose in 1998, significantly contributed to by this immigrant group,” i.e. it’s those Black Africans who are increasing our rate of HIV disease, not our racist coercion in testing. Black Africans are more than 200 times more likely to be “positive” on these tests. Rules of privacy and confidentiality are not adhered to; the doctors reason that hospital personnel have a right to know if a Black African has HIV so they don’t “catch” the AIDS disease. This despite the fact that not one single health care worker anywhere in the world has contracted AIDS through accidental exposure in the 23 years since the ‘epidemic’ began. Black Africans and their children are being coerced into these tests, where white Europeans are not. A Black African presenting with any medical condition, however unrelated to any possible HIV disease, to a New Zealand hospital suffers great pressure to get an HIV test. MOH and Statistics NZ figures demonstrate that Black Africans have a higher prevalence of HIV in New Zealand than the reported rate in extremely high risk and frequently tested prisoners in South African prisons. The prison population comprises intravenous drug users and men who have sex with men without condoms. Given that these prisoners are all tested every -24- Traditional African Clinic October 2008 Continued on page 36 African Traditional Herbal Research Clinic Volume 3, Issue 9 NEWSLETTER October 2008 FEATURED ARTICLES The Afrikan Traditional Herbal Research Centre Progress Report Nakato Lewis Blackherbals at the Source of the Nile, UG Ltd. October 2008 The concept of indigenous or local traditional knowledge refers to the complete bodies of knowledge, expertise, practices and technology, maintained and developed by people with long histories of close interaction with the natural environment. These sets of understandings, interpretations and meanings are part of a cultural complex that includes language, naming and classification systems, ways of using and recycling resources, rituals, spirituality and a worldview. Such knowledge provides the basis for local decision-making about many fundamental aspects of day-to-day life within these societies, such as hunting and gathering food, fishing, agriculture and animal husbandry, food production, water, health, and adaptation to environmental or social change. As in all traditional societies, Afrikan people have evolved sophisticated realms of knowledge, derived from experimentation or observation to explain, predict, and control natural phenomena. This indigenous knowledge often appears to differ from-or even run counter to-the scientific principles taught by colonial powers. Evidence of Afrika's store of indigenous scientific knowledge has emerged recently in a variety of disciplines. For example, living on the desert's edge, Afrika's nomadic pastoralists are acknowledged to be among the world's experts on famine and range management. The thousand-year-old cultures living south of Timbuktu along the Niger River in Mali consult written texts that we appreciate today, as a model of environmental conservation. Afrika's traditional plant breeders cultivated tropical gardens that contain as many as 150 intercropped species and recognition is given to the Afrikan for the development of a remarkably productive agricultural system. The continent's materia medica of more than 7,000 animal, plant, and mineral products for the treatment of illness is a resource that western-trained scientists are avidly copying and studying. Seldom documented, Afrikan indigenous knowledge (AIK) is passed orally from generation to generation. Unfortunately, scientific awareness of the value of Afrikan indigenous knowledge is growing at a time when such knowledge is under tremendous threat. It is in danger of disappearing, as a result of the evergrowing Western influences for rapid technological change and because the capacity and facilities needed to document, evaluate, validate, protect and disseminate such knowledge are lacking. For this situation to change, infrastructures, facilities, research, and financial resources are needed. More research needs to be done on AIK systems and more methods developed for dealing with it. Afrikan claims of indigenous solutions to specific problems by indigenous knowledge systems need to be validated and attempts made to improve or adapt those systems. This research should be conducted with people who possess the indigenous knowledge and with the local communities involved. There are signs of a growing demand for education systems in Afrika, tailored to local needs. It is these efforts that are providing increased attention to knowledge systems based in local traditions and cultures and the need to revitalise these systems from an educational point of view. Importance of Indigenous Knowledge In the past, modern science has considered methods of Afrikan indigenous knowledge as primitive. Many traditional practices, during the colonial period, were declared illegal by the colonial authorities. However, AIK has made and continues to make significant contributions to resolving local problems. From developing countries worldwide an increasing flow of information is being transmitted and the role that indigenous knowledge plays in a range of sectors. Besides alleviating poverty, this range includes such sectors as agriculture (intercropping techniques, animal -25- Traditional African Clinic October 2008 Continued on page 26 Continued from page 25 –The Afrikan Traditional Herbal Research Centre production, pest control, crop diversity, animal healthcare, seed varieties), biology (botany, fish breeding techniques), human healthcare (through traditional medicine), the use and management of natural resources (soil conservation, irrigation and other forms of water management), and education (oral traditions, local languages). Furthermore, through modern ethno-botanical research, indigenous knowledge is contributing to science in fields relevant to natural resource management. In particular, indigenous knowledge helps scientists understand the issues of biodiversity and natural forest management provide insights into crop domestication, breeding and management, and gives scientists a new appreciation of the principles and practices of 'slashand-burn' techniques in agriculture, agro-ecology, agroforestry, crop rotation, pest and soil management, and other areas of agricultural science. One of the major prerequisites for the entire process of collecting, applying and disseminating indigenous knowledge is the full participation of the local people involved. Full participation can be achieved only when the local communities are able to participate on an equal level. Capacity building is therefore a key issue, and vital if traditional knowledge systems are to receive the active support to sustain them. Capacity building must include training to better equip indigenous people and young scientists to carry out research on traditional knowledge, and to promote and develop that research to better appreciate traditional knowledge. This can be achieved through collaborations between national governments and Afrikan organisations and by placing indigenous knowledge on the agenda of science for development in general. Afrika is a natural treasure house, endowed with wonderful examples of physical and cultural diversity. Afrika is also a laboratory for studying the boundaries between modern scientific methods and technologies and traditional practices. Indigenous knowledge has a trans-generational, communal, spiritual and cultural nature. Western science is based solely on technological aspects of the physical world. Indigenous knowledge and western science should be seen as two systems of knowledge that can supplement, rather than compete with each other. Traditional Agriculture Traditional farming is an important reserve and source of biodiversity. It is still perhaps the only sustainable system. Ancient farmers developed sustainable agriculture practices, which allowed them to produce food - and fiber for thousands of years with few if any outside inputs. Many of these practices have been forgotten or abandoned in developed countries, but have continued to be used by many traditional, subsistence, or partially subsistence farmers in developing countries. Most traditional methods of agriculture were developed empirically, through millennia of trial and error, natural selection, and keen observation. Some of these practices, which often conserve energy, maintain natural resources, and reduce chemical use, are worthy of examination. Today over half of the worlds' arable land is farmed by traditional farmers. Many of their techniques are unknown or poorly understood, but have allowed them to produce crops and animals with minimal or no purchased inputs. Traditional farming systems often resemble natural tropical agroecosystems. This and their striking diversity give them a high degree of stability, resilience, and efficiency. Traditional farming, however, is being replaced by modern intensive farming systems in many parts of the world. This represents the loss of farming systems that are stable, sustainable and from which many valuable lessons can be learned. Although high yields of modern intensive agriculture have made it possible to feed the ever-increasing human population, it has been accomplished at the expense and to the destruction of the surrounding ecosystems. Traditional agricultural practices must be understood and conserved, before they are lost through the rapid advance of modern agriculture in developing countries. They are fertilizing the Earth on a global scale through intensive agriculture, fossil fuel combustion and widespread cultivation of leguminous crops. Evidence is growing that the use of huge additional quantities of nitrogen are exacerbating acidification, causing changes in the species composition of ecosystems. It also raises nitrate levels in freshwater supplies above acceptable limits for human consumption, producing an aquatic environment that favours plant over animal life in many freshwater habitats. Pesticide use causes the acute poisoning of 3.5 to 5 million people a year. Worldwide, 400 million tonnes of hazardous waste are being generated each year. About 75 per cent of pesticide use and hazardous waste generation occurs in developed countries. Despite restrictions on toxic and persistent chemicals such as DDT, PCBs and dioxin in many developed countries, manufacturing of these chemicals continues for export and remains widely used in developing countries. Microbial food-borne illnesses are the largest class of emerging infectious diseases. The use of antibiotics and -26- Traditional African Clinic October 2008 Continued on page 27 Continued from page 26 - The Afrikan Traditional Herbal Research Centre hormones in agriculture is growing. Their prolonged use on farm animals has resulted in cancerous tumours and unmanageable bacterial and viral infections in animals. Of particular concern, are the antibiotics and hormones fed each year to hogs, chickens, and cattle, specifically designed to reduce their bacterial populations and promote faster growth for food production. A major important fact is that the bacteria these antibiotics are designed to destroy are growing increasingly resistant to antibiotics and at a faster pace than if these antibiotics were used only to treat animals diagnosed with disease. This has created super-bugs and super infections in human and animals. Multinational corporations use genetic engineering to monopolize the seed supply and raise the cost of farming so that the western global agricultural industry can consolidate its control worldwide. Traditional farmers support billions of people on the planet by saving seeds from crops and replanting these seeds the following year. Most farmers cannot afford to buy new seeds every year, so collecting and replanting seeds is a crucial part of the agricultural cycle. Food has been grown successfully this way for thousands of years. The existence of genetically engineered crops goes against all the natural laws of nature, producing toxic reactions as well as food allergies. The safety of their long-term use is not established. Many research studies show that genetically engineered plants can harm wildlife and sensitive ecological systems, which Afrika must guard against. Genetically modified material contaminates more than two-thirds of conventional crops in the United States, dooming organic agriculture and posing a severe future risk to health. Because of the contamination, farmers unknowingly plant billions of GM seeds a year, spreading genetic modification throughout North American agriculture. This will become even more of a danger to health with the next generation of GM crops, bred to produce pharmaceuticals and industrial chemicals. Trade in genetically engineered food, crops and microorganisms is dominated by a handful of multinational corporations, the same corporations involved in the manufacture of pharmaceuticals, nutraceuticals, pesticides, herbicides and other chemicals. Today, most commercial farms are depleted of nutrients and natural soil organisms. Due to the convenience of synthetic fertilizers, herbicides, and pesticides, farmers no longer need to rotate their crops, which now grow faster and are accompanied by greater yields per season. If problems develop, they just add more man-made chemicals, a poison or a stimulant, to their crops. The soil on many commercially farms has become so unnatural that it no longer holds water normally and even requires more water, which contribute to waste and further leeching of nutrients from the soil. Many farmers no longer bother to develop mulch or plow old crops back into the soil. Pesticides destroy most of the living organisms in the soil, thus old crops cannot be transformed into beneficial soil. Traditional agriculture methods, such as cross-pollination or selective breeding, are based on natural reproductive mechanisms. These traditional methods will cross only one kind of plant or animal with a similar species. Fruits and vegetables grown organically show significantly higher levels of cancer-fighting antioxidants than modernly grown foods. Consumer interest in organic foods, produced without the use of pesticides, chemicals or genetic engineering, has ballooned in recent years due to increasing concerns about health and food safety. Researchers are beginning to appreciate that many traditional farmers in the developing world are still practicing farming methods that are in balance with the surrounding ecosystems, stable, sustainable and highly efficient. Portrayed as ignorant and not adaptive, traditional farmers have actually been utilizing very sophisticated methods of agricultural production for centuries. These farming systems can perhaps help the developed world to grow food with fewer chemical inputs, slow erosion, control pests, decrease our dependence on fossil fuels and feed an expanding global population. The challenge for the future is how to increase yields in traditional systems while retaining a certain measure of their integrity, in other words, to finds methods of sustainable intensification. Conversely, we need to integrate biological diversity into existing modern commercial agricultural systems in developed countries. There is evidence that the adoption of traditional conservation methods on large commercial farms can promote biological diversity (*FAO, 1996). Techniques such as crop rotation, intercropping, cover crops, integrated pest management, and green manures can be adapted for use in larger commercial systems. These practices can reduce dependence on fertilizers and pesticides and promote sustainable intensification. An integration of farming systems, combining the productivity of modern systems and the sustainability of traditional systems, could help to preserve biological diversity and feed a growing population without excessive damage to the environment. -27- Traditional African Clinic October 2008 Continued on page 37 Traditional Medicine Playing Important Role - Nduhura for enhancing Research and Development in traditional medicine. Uganda joins other African countries to commemorate the 5th African Traditional Medicine ay. The theme for this year is ‘Research & Development of Traditional Medicine in WHO African Region’. The Ministry of Health pledges its total support to all Scientists and Natural Chemotherapeutics Research Laboratory in particular for their effort in Research and Development of traditional medicine. A number of herbal formulations are being standardized to ensure that they are safe and efficacious. The Natural Chemotherapeutics Research Laboratory has managed to identify the research priorities in traditional medicine which is inline with Health Sector Strategic Plan. In Uganda and the rest of Africa, traditional medicine continues to play a very important role in health care delivery for primary health care. A large number of the population in Uganda tends to rely on traditional medicine and this has resulted in the tremendous rise in number of people using traditional medicine countrywide. As we commemorate this day therefore I call upon all scientists to embrace Research and Development of traditional medicine. This will add value to our natural products and herbal medicines for fulfilling the growing needs in quality and safety in natural products. We also need to ensure that our natural resources are conserved as we develop traditional medicine. Therefore, pharmaceutical companies, traditional health practitioners, conventional health practitioners have a lot to benefit in traditional medicine (herbal medicine) if Research and Development is embraced. This is an area Uganda has a competitive advantage. The government of Uganda is encouraging investment in this sector in order to create employment for scientific innovators. The World Health Organization (WHO) observes this day on every 31 of August. However, in Uganda, this day for this year will be observed in November 2007. The Republic of Uganda Daily Monitor November 6, 2007 The role of research and development in traditional medicine in Uganda is very important. There is great need for scientists and researchers to carry out comprehensive research and development of traditional medicine to ensure that validated and standardized products are used in health delivery systems. Most of our herbal formulations are not standardized to meet the minimum national requirement for registration with National Drug Authority. Public and private collaboration is crucial in the development of traditional medicine in Uganda. The Government of Uganda has come out strongly to support science based courses at the universities and science based researches. The millennium science initiative under Uganda National Science Council for Science and Technology is one among the many examples of Government initiatives to support research and development. This is an opportunity for all the stakeholders in traditional medicine to encourage our young scientists to get involved in research and development. The Ministry of Health public private partnership policy for Health is intended to streamline research and development of traditional medicine. The National policy on Traditional and Complimentary Medicine (TCM) is due to be tabled to cabinet. This Policy forms background I wish all Ugandans joyous celebration of the 5th African Traditional Medicine Day. FOR GOD AND MY COUNTRY Minister of State for Health General Duties, Honorable Richard Nduhura ☻☻☻☻☻☻ Enhancing Research in the WHO African Region Research and Development of Traditional Medicine in the WHO African Region Daily Monitor November 6, 2007 In Africa, close to 80% of the population continue to rely on traditional medicine for health delivery. In most cases traditional medicines has been found within reach, easy access and with minimal side effects. However this is not to say it’s free from unwanted side effects. Lack of proper standards for herbal medicines has affected its integration into the National health care delivery systems for African countries including Uganda. The Natural Chemotherapeutics Research Laboratory (NCRL) is faced with challenges of evaluating large numbers of herbal medicines locally used in order to justify their therapeutic claims as well as demonstrate their clinical efficacy. While herbal medicine is useful, it poses lots of chal- -28- Traditional African Clinic October 2008 Continued on page 29 Continued from page 28 – Enhancing Research in the WHO Africa Region and 26th July 2007 was a great land mark in the history of NAPRECA, Uganda. lenges for example, safety and efficacy before it can sustainably be integrated into the health care delivery systems. This is the reason the World Health Organisation (WHO) has strongly come out to support a number of countries with Research and Development guidelines in traditional medicine. The NCRL was privileged to be treated to a presymposium activity that revived research and development in the light of hinging on ethnopharmacology and the need to be proactive to environmental issues. All these are to ensure a successful future in research and development in natural products. There is also added financial support from WHO for institutions to develop policies on traditional medicine and clinically validate herbal therapies. Despite the challenges, NCRL has been at the forefront of Research and Development of herbal medicine in Uganda. A number of herbal formulations are being standardized to ensure that they are safe and efficacious and thereafter be considered for registration with National Drug Authority (NDA). The Network on Medicinal Plants and Traditional Medicine Project with a Secretariat at NCRL, supported by International Development Research Centre (IDRC), Ottawa, Canada has also assessed current research activities on medicinal plants and traditional medicine in E. Africa, identified the research priorities in medicinal plants and traditional medicine, enhanced research capacities and harmonized research approaches and methodologies for sustainable management of medicinal plants. The project has promoted collaborative research projects in medicinal plants and traditional medicine within the E. African countries and strengthened the capacity of traditional health practitioners in Research and Development in traditional medicine. A meeting on the institutionalization of the Network within the Lake Victoria Basin Commission (LVBC) of the East Africa Community was held in Kampala in September 2007. It was attended by representatives from the LBVC, Kenya, Tanzania and Uganda. It was recommended that the Network evolves into a partnership in order to carry out activities identified in the strategic framework of Network of Medicinal Plants and Traditional Medicine (EA). The LVBC is ready to embrace the Network if it evolved into a partnership and this will also bring in Rwanda and Burundi as they are now members of the East African Community. The recently conclude Natural Product Research in East and Central Africa (NAPRECA) Conference threw light on recent advancement in Natural Product Research and Development. This conference was able to revive hope about the possible cures of the forgotten or neglected tropical diseases for example, trypanosomiasis, onchorcirciasis, etc from our biodiversity. The meeting of great renowned scientists in such a high profile conference hosted by Makerere University between 22nd Through the above theme, NCRL will strengthen Research and Development of herbal medicines in the country though wider institutional collaborations with other institutions e.g., Uganda Industrial Research Institute, National Drug Authority, Uganda National Council for Science and Technology, Uganda National Bureau of Standards, Uganda Export Promotion Board, Uganda Investment Authority and a number of academic Research Institutions. Currently with collaboration with National Drug Authority, some of the herbal formulae are to be registered and these products will be able to be sold in pharmacies and drug shops around the country. In addition, a number of private investors have started to invest in herbal pharmaceutical processing of local herbal products which range from decoction, infusions, syrups , cosmetics and many others, The former National Enterprise Corporation now NECHealthworld Ltd is due to commence manufacture of some of the herbal products in Uganda. Many local and international private investors have contacted NCRL and Ministry of Health to discuss issues of partnership in research and development of herbal medicine. These among other include Republic of North Korea, China, Egypt, Iran and countries within the East African region. The Government is currently in the final stages of developing the National Policy on Traditional and Complimentary Medicine (TCM) and soon to discuss the traditional medicine practice Bill as developed by Law Reform Commission in 2002 that will regulate practice of traditional medicine and bring it to national and internationally acceptable standards. The policy and bill are waiting input from stakeholders before the bill is tabled to cabinet. The Ministry of Health through support from World Health Organization and collaboration with stakeholders is also developing code of ethics for the tradition healing practice. The TCM Policy, Traditional Medicine Practice Bill and Code of Ethics for Traditional Medicine will stream-line Research and Development in Traditional medicine. -29- Traditional African Clinic October 2008 Continued on page 30 Continued from age 29 – Enhancing Research in the WHO African Region As a constituent sector of the proposed Uganda National Health Research Organization (UNHRO), NCRL is to become a Research Institute for Traditional and Complimentary Medicine (RITCOM). It will therefore have a wider mandate to encompass; agronomy, product development, legal and social aspects as a holistic approach to research and development in traditional medicine and healing practices. With this year’s theme for the 5th ATM celebrations, stakeholders in traditional medicine will be able to do research and development in traditional medicine by; • Adding value to natural products (herbal medicines) as well as promote investment in this sector thus support the Poverty Eradication Action Plan (PEAP) and Plan for Modernization of agriculture (PMA) policies • Improving conservation of natural resources for their sustainable utilization. • Improving livelihood of the poor people by ensuring that they are healthy. • Strengthen the capacity of individuals and local enterprises in research and development in her medicines. • Ensuring that herbal medicines are standardized to meet the minimum requirement for registration and acceptability in the National health care delivery system. Natural Chemotherapeutic Research Laboratory is very grateful to WHO, IDRC and other donor partners for the financial support to te government of Uganda for Resarch and development of traditional medicine in Uganda. Natural Chemotherapeutics Research Laboratory would like to wish everybody a successful celebration to mark the 5th African Traditional Medicine Day. ☻☻☻☻☻☻ More Herbal Medicines Flood the Ugandan Market Stella Nakakande Daily Monitor March 22, 2008 Armed with the art of psychology, witchdoctors devised ways to ensure that the secret of their non-possession of supernatural powers would be known only to a few trusted practitioners,” writes Br. Anatoli Wasswa of the Banakaloli Brothers in his book Unveiling Witchcraft. Br. Wasswa is a traditional herbalist. In Uganda, herbalists are frequently confused with traditional healers commonly known as witchdoctors. Herbalists are often criticized because of the negativity the latter portray. They on the other hand insist that their approach to disease treatment is scientific with no mystical power to their medicine. According to Mr Elijah Ntege, they like in modern science, have laboratories where they carry out tests to ascertain the nutrient content of leaves, animal bones, ash, soil and their curative powers in relation to the disease. Traditional medicine is at the core of the matter. In many places in the country are structures with posts reading Herbal Research Clinic. These have been on the rise lately; you are often lost for choice in places like Katwe where every shop has this label. And like it is said, necessity is the mother of invention; the initiator of al this research seems to have been the HIV/Aids epidemic in the early 90s. Dr. Abubakar Rasid Lukwago of the Dr. Yakubu Lukwago Herbal Research clinic in Kasubi says that his late father, Dr Rashid Lukwago who focused on HIV treatment, founded the clinic in 1990 on William Street. “It begun in 1990 with the onset of the HIV epidemic,” he explains, adding that “our father was mainly handling people living with the virus mainly.” These doctors are true medical personnel as per the public eye. They wear white clinical coats, examine patients, and prescribe doses; the clinics are jammed with patients seeking healing for their ailments. They are even referred to as “doctor”; you do not have to swear by the ‘Hippocratic oath’ after all to earn the title. Nonetheless, what is traditional medicine all about and why is the herbal research sector suddenly mushrooming? Based on Research Dr Yakubu Lukwago explains that theirs is treatment and research that has grown over the years. “We have moved on from HIV/Aids treatment we can now handle all disease apart from cancer and sickle cells where we can only offer tranquilizers since these have no cure.” “We even check for UTI, which is by far the commonest infection in women,” he as. When it comes to HIV, Dr. Lukwago says, they have the right medicine to boost the immunity and get rid of unwanted symptoms like lip ulcers commonly called “red lips”, loss of appetite, chronic diarrhoea, Herpes Zoster (kisippi) and cough among others. For the lip ulcers and -30- Traditional African Clinic October 2008 Continued on page 31 Continued from page 30 – More Herbal Medicines Flood the Ugandan Market Herpes Zoster, the clinic has a powder and medicated Vaseline applied on the infected area. “It takes five to seven days for these to disappear,” he clarifies. “They even have antibiotics for cough infection as a result of Tuberculosis. The authenticity of all this of course can only be proved by the user although one wonders why these medicines have no names. In Kamengo Herbal Research Clinic in Katwe, every bottle has a label of the diseases treated apart from that containing medicine for HIV/Aids. The attendant knows it by the liquid’s colour perhaps and its positioning on the shelves. Like ARVs, one should never run out of stock of this, the doctors tell me. Mysterious They are also hesitant to reveal the contents of their medicine. “We mix a couple of things,” they say. For each disease, there is a complex set of ingredients. The contents are given names like “red liquid” or “black powder”. The source of these is also mysterious. “We get trees from Saudi Arabia, South Africa, Somalia, Tanzania and so many other countries,” Dr. Lukwago says when asked to explain their origin and names. “We name the species ourselves so they have no definite naming.” To an onlooker, it is as if they are reluctant to reveal their “magic mixtures”; they want to stay around much longer and no kind of coercion is enough to make them name these species. They will only restrict themselves to the ingredients noting that the main composition of red liquid is magnesium, zinc and potassium required to boost one’s immunity. The explanation ends there. More interestingly, these herbalists have scientific labs not only for research but also for analysis of one’s health. They, like with modern medicine, diagnose and check for the disease, before any prescription is made. Prices range from Shs4,000 to Shs70,000 for the CD4 count performed for people living with HIV. They also have pregnancy tests. Interestingly though, only one of these herbalists, Elijah Ntege of the Babakaloli Brothers said they do not offer HIV/Aids treatment. “What should we treat in HIV?’ he wondered. Well, that begs the question, what do others treat? Have You Tried Something Herbal? Rachel Kabejjaa Sunday Monitor July 12, 2008 More people are turning their attention to medicine, herbal or natural beauty supplements, and home remedies because been discovered to be an effective means ailments and barely have side effects. alternative products, they have of curbing When it comes to beauty solutions, herbal alternatives are made from natural products. These products are always less or unprocessed hence making them suitable for all skin types. For ages, our great grandparents lived on such products and they were healthy and looked good like the Egyptians for instance and used herbs like fenugreek and roses to prevent wrinkles. Then processed cosmetics became popular only for table to turn again to herbal solutions hence the boom of both international and local industries manufacturing herbal jellies like Samona and Movit herbal jellies, soaps creams, massage and aromatherapy oils, beauty spas, reflexology, bath gels, moisturizers and herbal powder containing natural combination of neem tree, basil flowers, aloe Vera, oregano, lavender and other naturals. Studies have found that aloe Vera which is a popular ingredient in herbal products has antimicrobial, anti-inflammatory, an immune-stimulating actions as well as large quantities of vitamins E and C, zinc, and amino acids. Thus the healing properties of this traditional plant have finally been isolated. Dr Liu Zheng of Natural Chinese Herbal and Acupuncture Clinic Kira road says that herbal products are also cost friendly and don’t have animal products hence causing less or no irritations to the skin. Herbal beauty products also come with advantages like being easy to prepare, are readily available even in your home compounds. They have no known side effects and (with some exception) are absolutely safe even for prolonged use, and they can bring long lasting results and even complete healing according to www.theherbalbeauty.com. The biggest known disadvantage is that some treatments may take months, even years, depending on the problem, for complete healing. However, the first results usually show after 10-14 days, which gives sufferers a reason to continue with the treatment. ☻☻☻☻☻☻ -31- Traditional African Clinic October 2008 ☻☻☻☻☻☻ Ugandans Now Live Up to 50 Years – Report This growth has been mainly attributed to good policies and governance, which the report says “matter a great deal.” Peter Nyanzi Ms Obiageli Ezekwesili, the World Bank Vice President for Africa Region said over the past 10 years Africa has recorded an average growth rate of 5.4 per cent “which is at par with the rest of the world” but that the ability to support, sustain and diversify the sources of these growth indicators “would be critical not only to Africa’s capacity to meet the MDGs but also to becoming an exciting investment destination for global capital.” Daily Monitor November 20, 2007 Uganda is one of only two countries that have made the greatest gains in improving life expectancy in the last 10 years, a new World Bank report has shown. According to the African Development Indicators (ADI) 2007 that was released last week, the life expectancy of Ugandans has now climbed by seven years to 50, up from just 43 in 200l. With Tanzania behind at 46.3 and Kenya at 49.0, Uganda is now the only country above the 50 mark in the Great Lakes region and therefore the best country for those who want to live a bit longer. Ugandan mothers also have a better chance to survive during pregnancy with a maternal mortality ratio of 880:100,000 live births compared to Tanzania’s 1,500:100,000 and Kenya’s 1,000:100,000. But the situation is not as good for children under-five with a mortality rate of 136:1,000 live births compared to Kenya’s 120:1,000 and Tanzania’s 122:1,000. Generally, the report says because of HIV/Aids, TB, malaria, and other diseases, improvements in life expectancy have stalled in some countries and retreated in a few others. Uganda is also largely lagging behind in adult literacy rates with only 57 per cent of females able to read and write compared to Tanzania’s 62.2 per cent and Kenya’s 70 per cent. The report says poor health and poor schooling hold back improvements in people’s productivity and the chances of meeting the Millennium Development Goals (MDGs). Malaria is still a big concern in the region with 152/100,000 Ugandans dying of the disease compared to Kenya’s 63/100,000 and Tanzania’s 130/100,000 people. But the report is generally positive about growth prospects for Africa where about 41 per cent of the people still live on less than $1 (Shs1,700) a day. On the continent, Uganda is listed as second among the countries with the largest proportion of people living in the rural areas (87.4 per cent) next to Burundi (90 per cent). The report says after years of stop-and-start results, many African economies “appear to be growing at the fast and steady rates needed to put a dent in the region’s high poverty rate and attract global investment.” The report says Africa now enjoys better growth prospects because the leaders have under taken major reforms over the past decade. But it decries the negligible role the private sector has played in improving the living conditions of the citizen. It says accelerating and sustaining growth requires improving Africa’s investment climate, spurring innovation, and building institutional capacity to govern well. ☻☻☻☻☻☻ Continued from page 21 - Scientists Map Genomes of Malaria Parasites Some of its genes closely resemble a human gene involved in regulation of the immune system. The World Health Organization said malaria killed 881,000 people and infected 247 million people worldwide in 2006, the latest year for which figures were available. Some malaria experts say those numbers underestimate the problem. Most deaths occur in Africa and are caused by the Plasmodium falciparum parasite, whose genome was mapped in 2002. The researchers found the vivax genome was similar in many ways to the falciparum parasite, meaning that certain vaccine approaches being tried against the African parasite may be worth trying against this one. "During the course of evolution, malaria parasites have devised different tricks to avoid being detected and dampen the host immune responses," Pain said by email. "Thus, it has been rather difficult to find a single parasite protein that could be used as an effective vaccine candidate which would provide effective and long-term protection against all parasite strains circulating within a given population at a given time," he said. URL: http://www.msnbc.msn.com/id/27088500/ -32- Traditional African Clinic October 2008 ☻☻☻☻☻☻ African Traditional Herbal Research Clinic NEWSLETTER October 2008 FEATURED ARTICLES Unified Field Theory of Disease and Nutritional Causation or Predispositions Volume 3, Issue 9 Professor Charles Ssali Mariandina Nutritional Health Products Disease is any type of disorder or body function which is a result of: 1. Bacterial, viral, fungal infection. 2. Degenerative change in cells. 3. Congenital and Hereditary. All can be traced back to some nutritional deficit. All diseases would be eliminated from man if the victim were to be fed on a properly balanced diet right from the moment of conception. The development of a fertilised egg into a fetus depends on the availability of nutrients to power and nourish the developing fetus. These nutrients act as free radical scavengers to protect the body cells from the harmful effects of free radicals that come out of body metabolism. The free radicals are capable of disrupting fetal development. The invasion of body tissues by bacteria, viruses and fungus is dependent on the absence of enough nutrients to strengthen the immune system, which mops up the organisms. The free radicals are the ones which promote the reproduction of all the invading organisms and in turn the organisms promote the production of free radicals. It is obvious that even congenital or developmental abnormalities can be traced back to nutrition. Nutrition may be affected by the use of toxic substances or drugs that affect cell division leading to abnormalities and congenital defects. One such chemical is thalidomide and the virus called rubella. All these lead to birth degenerative diseases like diabetes, asthma, vascular/heart diseases are all traceable to some nutritional deficit, which causes the cell death in the organs concerned. The pancreas loses the ability to secrete insulin as a result of the degeneration of the cells in the islets of langerhans. These specialist cells die as a result of a nutrition lacking in vitamins and minerals. Taking white sugar from which molasses containing vitamins and minerals are removed during processing leads to one such ways by which diabetes develops. When these nutrients are supplied to the person with diabetes, the situation improves rapidly back to normal. All body cells develop from what are called stem cells in the embryonic stage. A stem cell requires proper nutrition as found in vegetable foods in their original unprocessed state in order to develop with the adult specialised cells as you find in various body organs like the brain, liver, glands, skin, muscle, bones, intestinal and respiratory tracts. The lack of liberal supplies of these nutrients we find in fruits and vegetables creates a deficiency in the availability of vitamins like A, B, C etc, minerals like iron, zinc, selenium etc, besides plant hormones, enzymes and chlorophyll all of which play an important role in the proper development and specialisation of body cells. Examples of congenital defects that can be traced back to nutrition include, heart defects, spina bifida, missing limbs, hydrocephalus and many others. A liberal supply of vitamins and minerals are vital in this respect. Infections of the mother during pregnancy include viruses like rubella which only occur where antiviral nutrients like vitamin A, C and E are in short supply. The virus disrupts the proper cell divisions required to complete some body organs like the heart etc. The immune system which protects us from all infections depends on nutrition to produce antibodies and the necessary defence cells like macrophages and lymphocytes. Any deficiency in the necessary nutrients results in weakening of the immune system which is followed by an invasion of the body of bacteria viruses, fungus and even degeneration of body cells. Nutrients help the body to clean itself by mopping up free radicals that we produce during cellular metabolism. These free radicals include hydrogen peroxide, which attacks cell structures if left in position for too long. It can attack vital structures like the cell membrane, the nucleus and mitochondria. The damage they inflict on the cells is what can cause conditions like diabetes -33- Traditional African Clinic October 2008 Continued on page 34 Continued from page 33– Unified Theory of Disease… when insulin secreting cells (islets of langerhans ) die in increasing numbers till it results in insulin deficiency called diabetes. When nutrients are replenished, the cells regenerate and diabetes can be cured. The same occurs in other body cells where cancer occurs because of the destruction of mitochondria making metabolism using oxidation of glucose impossible for lack of the necessary enzymes in the mitochondria (KREB’S cycle) which power the process. This leads the cells to generate heat energy using fermentation processes and the production of lactic acid. This is the way cancer occurs in body tissues like in the breasts, uterus, lungs, glands and other tissues. The cure for cancer must therefore address this anomaly by reconstructing the damaged cell structures and restoring normal body metabolism. Powerful antioxidants, which act as free radical scavengers in the affected parts of the body help the tissues to detoxify itself and prevent further cell, damage from free radicals. The oxygen that is released by hydrogen peroxide can attack cell structures and cause the equivalent of iron rust in the body. In situations like these, one requires to drink a lot of water in order to enable the kidneys to excrete those impurities from the blood circulation where they may continue causing traumatic effects on tissues. Water is an essential part of our nutritional requirements. If the body is denied water supply, it deteriorates rapidly because of dehydration and accumulation of toxic impurities. These impurities which accumulate in tissues cause body damage by depleting the supplies of nutrients from the food taken in daily. The ageing process is perpetuated by this growing nutritional deficit. As we grow we cut down on our intake of the essential nutrients of vitamins and minerals. The sum total of the nutritional deficiency and chronic dehydration is the progressive ageing process we observe in everyday life. In such a situation the body cells fail to reproduce themselves as they should by replacing themselves with identical copies. This is why the hair begins to lose pigmentation and becomes gray and the skin loses its elasticity, eventually becoming rough and wrinkled. This is the reason why cancer incidence increases with age or pollution in the internal and external environment. If we look after ourselves properly by taking a well balanced diet consisting of unprocessed fresh vegetables and fruits, then drink the required amounts of water, then we would be able to maintain our health status close to ideal for many years. Medicinal herbs are no more than foods with the required nutrients to correct the cellular nutritional deficiency that led to the diseased state. The use of Contraceptive pills, over use of antibiotics and smoking are some of the forms of drug abuse which drain heavily on nutrients because of the increased need for detoxification. This is the reason why those who indulge in such practices develop cancer of the breast, lungs, uterus and prostate. Others develop diabetes, Asthma and blood pressure because of the nutritional deficit created by the increase in the demand for nutrients for the detoxification of free radicals. A disease state like AIDS is a complex manifestation of nutritional deficiencies that include vitamins, minerals, plant hormones, amino acids and enzymes. The body needs plant ingredients found in leafy vegetables e.g. chlorophyll, lecithin and many others. The HIV invades the body by penetrating its cells which are deficient in nutrients and abounding in free radicals. This window of opportunity occurs in all people who indulge in junk foods, drug abuse, over use of antibiotics, fizzy drinks with artificial sweeteners. These factors depress the immune system allowing the virus to successfully establish itself in the body. If the free radicals are regularly mopped up using the free radical scavengers called antioxidants as found in fresh fruit and vegetables, then the virus and cancer cells are eliminated by the power of the immune system. During sexual union the male partner ejaculates about 2 mls of semen which carry the male spermatozoa. This semen also carries with it nutrients to be used by the sperm and the early embryo. To collect these nutrients in the semen, one pint of the male partner’s blood is stripped of all these elements which include vitamins, minerals, enzymes, hormones etc, etc. Repeated ejaculations can deplete the male partner’s blood of essential elements required by his immune system. The result of such a situation is to make him vulnerable to infections like viruses and STDs including HIV. This is the reason why promiscuous males may easily develop AIDS which means Acquired Immune Deficiency Syndrome. Semen is rich in zinc and selenium both of which are very important for strengthening immunity by providing it with specialised cells called T helper lymphocytes. These T helper lymphocytes go through the thymus gland which prepares them for the battlefield capability against virus invaders. The thymus gland requires a lot of zinc to do the job. Selenium is needed to make the body’s antioxidant called glutathione peroxidase. This natural antioxidant is very important in clearing out hydrogen peroxide from the body cells. A diet rich in these nutrients will play an important role in protecting us against all infections and cancer. The prostrate gland in the male is the equivalent of the uterus in the female. Both these organs are prone to developing cancer if nutrition is deficient in these essential elements among others. On the other hand, female partners stand to gain nutrients -34- Traditional African Clinic October 2008 Continued on page 35 Continued from page 34 – Unified Theory of Disease…… which are drained out of the male partner’s blood. Most of the semen’s essential ingredients are absorbed into the female circulation through the birth canal. This provides her with the elements mentioned above for added protection against nutritional deficiency diseases that come as a result of a weakened immune system. This explanation could account for the survival phenomenon observed among professional female sex workers in Kenya and Uganda. These prostitutes have been found to survive HIV infection despite their risk factors. It has also been observed that these sex workers begin to succumb to HIV/AIDS when they retire from their profession. This would eliminate the original theory that they have a special genetic make up that protects them against HIV. I am of the opinion that it is the constant liberal supply of essential nutrients that boosts their immunity to the optimum levels capable to resisting STDs. Herpes Zoster which is a result of chickenpox virus manifesting itself as blisters on the skin is another example of the power of the immune system. This virus only surfaces when the body is malnourished and immune deficient. The development of cancer cells starts when the natural killer cells that hunt and destroy them are weakened by poor nutrition. This poor nutrition may be a result of ingesting overwhelming amounts of toxic substances that require large amounts of nutrients to excrete through the kidneys. If such nutrients are not available then the immune system is weakened and the natural killer cells fail to cope with the cancer cell development in the tissues. This if kept up for long enough, then the particular site develops cancer. These toxic substances like aspartame (Nutrasweet), contraceptive pills, radioactive materials, alcohol, hydrocarbons, asbestos etc, etc. These elements cause the production of free radicals to rise and stagnate in tissues. This stagnation leads to the damage of cell wall, DNA cross links and mitochondria structural damage. This DNA damage leads to genetic mutation and cancer changes. The damage to mitochondria structure leads to the failure of the cell to metabolise glucose using oxygen. As a result of this failure, the cell turns to fermentation to produce heat energy with the production of a toxic lactic acid. This is what cancer cells do. They multiply uncontrollably and destroy normal tissues in the neighbourhood. Some of these uncontrollable cells break off and carry their characteristics to other parts of the body as metastasis that spread destruction and death. This process can be halted by providing the tissues with the required nutrients to repair the cellular damage in DNA and mitochondria. These nutrients must also strengthen the immune cells to be capable of destroying the cancer cells. This is possible through the use of herbal nutrients which contain the necessary ingredients to do the job. This has been achieved in cases of breast cancer, cancer of uterus, melanoma and other cancers. Hormone dependent disorders like diabetes, thyroid gland dysfunction, menopause, libido and many others can be eliminated by providing these necessary nutrients by using diet and where required, food supplements. Menopause and loss of virility comes because of the progressive reduction in our food intake as we grow older. As a result of eating processed foods like white sugar, white flour and processed grain where the nutrients are removed and fed to lower animals, we develop deficiency diseases like diabetes, scurvy, eczema, lupus and asthma. These come about because our body’s immune systems have been programmed wrongly because of introducing adverse antigens into the body through vaccinations and inoculations. All these immunity or autoimmune disorders could be corrected by providing the body with the nutrients the body needs to reprogramme the immunity. By providing these supplements we have been successful in eliminating all symptoms and signs of lupus, asthma, eczema, thyroid gland problems and so on. Stroke which is a result of the blocking of blood clotting could be eliminated. The underlying disorder is in the metabolism of cholesterol leading to partial or complete blockage of a blood vessel. Where there is a blood clot or a ruptured blood vessel and bleeding, you find an accumulation of free radicals, white blood cells in the clot. This pathology needs nutrients to put it right. The cholesterol needs nutrients to facilitate its breakdown into energy. The blood clot and the repair of the damaged blood vessel will be completed by the white blood cells. We have seen this happen in many cases of stroke where paralysis disappeared within weeks or months when the necessary nutrients were provided to the patient. Brain and nerve disorders may develop because of using too much alcohol or a diet deficient in vitamins and minerals. Even psychiatric disorders are a result of the body’s failure to make the right nerve transmitters for lack of the proper nutrients. Where these mental problems existed, we provided the patients with nutritional supplements and an improved diet. The result was an improvement or recovery from the dementia of a psychiatric problem. As a result of the above observations as summarised, the following conclusion was inevitable. The Unified Field Theory of Disease and Nutrition (establishes) postulates that all disease states have their origin in some form of malnutrition at one stage or another. Even those arising from genetic defects could be attributed to the influence of a mutation that occurred because of a nutritional defect in the diet of the individual or alternatively the mutation -35- Traditional African Clinic October 2008 Continued on page 36 Continued from page 35– Unified Theory of Disease… persisted because of lack of proper nutrition. All disease states whether they are congenital, infective, and degenerative have a nutritional factor in their causation, promotion or elimination. http://www.blackherbals.com/mariandian_nutritional_health_pr oducts.htm ☻☻☻☻☻☻ Continued from page 24– To All African People Living in New Zealand 6 months, how can it be that clean-living, monogamous Africans in New Zealand are more likely to have HIV disease? There is something very wrong with this picture. Black Africans are much more likely to have a false positive test result due to exposure to TB, malaria, leprosy, and inherited blood disorders like sickle cell anaemia, malnutrition and many other factors. MOH statistics also demonstrate that over 300 Black Africans in New Zealand at this time have HIV disease. Many if not most of these likely represent false positives, but people are instructed to take anti-HIV medicines that are extremely harmful (and more so to Black people). In the case of Black African children, the parents are being ordered by the courts to give their children the anti-HIV medicine. Almost every person taking these drugs experiences severe and life-threatening side effects. Most adults decide the treatment is worse than the disease and stop taking the drugs. Black African children do not have this right according to the doctors. Doctors are lying to the courts by stating that HIV-infected Africans pose a risk to the wider community if they refuse anti-HIV drugs; even the manufacturers drug prescribing sheets state that taking the drugs does not prevent transmission to others. In any event, HIV appears to have extremely low transmissibility; a study in the US followed hundreds of couples where one partner was positive and the other negative for 10 years. Twenty five percent of the couples did not use condoms regularly, and 47 couples reported having unsafe sex, but not one single negative person became positive. It is certain that many Africans have died from taking the anti-HIV drugs. More than 20% of Black Americans have a genetic difference in the way their body processes the drugs, which can result in blood drug levels three times higher than they should be – a potentially lethal dose. In Black Africans this genetic difference is likely to be higher than 20%. When the African person dies from these drugs, the doctors write “AIDS” on the death certificate. We feel these issues need to be raised publicly; Black Africans have a right to know these facts. An article high- lighting these concerns is in the process of being written and will be published on the scoop.co.nz website, but it isn’t enough. I am hoping that as a prominent African in NZ you can help bring to light these terrible injustices. We have been working with 2 excellent human rights lawyers on one individual case, and the lawyers would be happy to instigate a class-action lawsuit on behalf of all Black Africans who may have been harmed, or whose rights have been infringed by the racist medical system in New Zealand. Yours sincerely Felix Mwashomah & Cathy van Miert Tel: 09-5277257, or 09-5261954. ☻☻☻☻☻☻ Africa: Researchers Record 'Major Breakthrough' Against Malaria Abimbola Akosile With Agency Report Lagos This Day (Lagos) 15 July 2008 Australian scientists yesterday identified a potential treatment to combat malaria, a global scourge, which kills about 300,000 Nigerians, mostly children below five years, annually. According to a report on the British Broadcasting Corporation (BBC) website, researchers in Melbourne believe their discovery could be a major breakthrough in the fight against the disease; where the malaria parasite produces a glue-like substance which makes the cells it infects sticky, so they cannot be flushed through the body. The researchers, according to the report, have shown how removing a protein responsible for the glue can destroy its stickiness, and undermine the parasite's defence. The malaria parasite, named Plasmodium falciparum, effectively hijacks the red blood cells it invades, changing their shape and physical properties dramatically. Among the changes it triggers is the production of the glue-like substance, which enables the infected cells to stick to the walls of the blood vessels. This stops them being passed through the spleen, where the parasites would usually be destroyed by the immune system. -36- Traditional African Clinic October 2008 Continued on page 42 stimulate new ties with business and avoid damage to the environment Continued from page 27 – The Afrikan Traditional Herbal Research Centre Food Science The food production and delivery chain is a complex intersection of several sectors of the economy. The farmer produces raw agricultural commodities. The commodities are purchased by food processors that in turn sell or distribute the product to wholesalers. The wholesalers market the products to retailers who sell the raw or modified agricultural products to consumers. Throughout this chain there are opportunities for product loss through spoilage and spillage. Obviously post-harvest losses can be reduced if there is a value-added post-harvest system in the country that properly stabilizes food for the food delivery system. Such a value-added sector is dependent on several factors including a dependable supply of indigenous raw agricultural commodities, an economy that supports investment in hardware and industry, a regulatory system that fosters a fair and competitive market structure, and a well-trained, educated work force. It is this last item, a well-trained and educated work force that is addressed in this proposal. Uganda represents a large area, capable of producing a wide variety of agricultural commodities. The majority of the current food needs are produced locally, with the remainder being imported. Much of the imported foods are fully processed and packaged when they arrive and inserted immediately into the distribution and marketing systems. One obvious mechanism to enhance the local economy is to convert raw commodities into consumer ready products locally. The transfer of knowledge and technology enhances opportunities to process indigenous products to local tastes and customs, providing jobs, leading to economic stability. Exporting these products also generates much-needed foreign exchange and brings real development to the country and the region. In this way, developing countries are able to claim a share in global markets, thereby bringing prosperity to their people. Moreover, the benefits of knowledge and technology transfer with respect to traditional agriculture and food science can help to: • Develop programs and policies that strengthen farmers, businesses, and markets • Increase rural education and training and build public institutions • Expand traditional agricultural research and outreach to exploit existing and new technologies, such as food science (processing, preservation and packaging), and information technologies, to • Coordinate food and agricultural programs with actions to combat poverty, and; • Increase food production for intra and intercontinental trade with other Afrikans/Blacks throughout the Continent and the Diaspora. In Uganda, for example, the use of natural spices and preservatives such as bird peppers, pimento, cloves, and cinnamon was discouraged by colonial powers and the medical community. African bird pepper is one such spice that grows wild all over Uganda and is extremely beneficial to health. For 10,000 years, the chili pepper has been used as a natural preservative and for such physical ailments as poor circulation, regulating blood pressure, digestion, and respiratory problems. In Jamaica, bird pepper was used by the Maroons (Africans), to naturally preserve meat and food. Obtaining informational access to Western research libraries and computer databases could go far in providing much needed information on such topics not readily available on the Afrikan continent. Afrikan Traditional Medicine (ATM) In all countries of the world, there exists traditional knowledge related to the health of humans and animals. Presently, eighty percent of the world’s populations still depend upon traditional and indigenous knowledge in medicine and herbal practices. In Afrika, traditional healers and the herbal remedies made from plants play an important role in the health of millions of people. Afrika has a long and impressive list of medicinal plants based on local knowledge. Based upon holistic principles, this science pre-dates Egyptian medical science and is between 20,000 and 100,000 years old. In fact, it is the oldest medical science on the planet. Afrikan health practitioners are devoted to teaching individuals how to improve their physical, mental, and spiritual health through preventative lifestyles. Doctors and health personnel have continued to shun traditional medical practitioners despite their contribution to meeting the basic health needs of the population, especially the rural people in developing countries. Developing countries have begun to realise that their current health systems are dependent upon western technologies and upon western medicines that are expensive and whose medicinal supply is toxic, erratic at best or non-existent. The ancient Afrikans believed that a healthy immune system is responsible for the health and healing of the human body. From this premise, health problems occur as the result of “something lacking” in our nutrition, -37- Traditional African Clinic October 2008 Continued on page 38 Continued from page 37 - The Afrikan Traditional Herbal Research Centre leaving the human body vulnerable to disease. Afrikan medicine is a nutrient based system. A diet and lifestyle deficient in vital nutrients makes us susceptible to opportunistic infections, and cellular disorganisation (cancer). Western doctors believe that the body destroys itself with disease and that harmful bacteria and viruses are trying to kill good bacteria and viruses. Therefore, they must give toxic, poisonous drugs and vaccines to stop the body from killing itself. The Afrikan system of health disagrees with the idea of germs being the sole source of disease. Their philosophy is consistent with the laws of nature, based upon an ancient belief in the body’s natural ability to heal itself when given the appropriate herbs, seeds, and foods. Moreover, our African biochemistry requires a type of nutritional support (African Dietetics) that is not readily available in western cultures or through western medicine. The science of African biochemistry is based on the biochemical molecule, melanin. The lack of melanin-sustaining foods (which can be found in plant phyto-nutrients) is one of the major causes of our nutritional deficiencies leading to disease. Currently, we are witnessing a breakdown of western European systems to cure diseases, derived from both natural and unnatural causes. Most pharmaceutical drugs, developed primarily to relieve symptoms, do not cure diseases. Vaccines were developed to immunize against disease, but can also be use to spread disease. For example, immunization by vaccination has been the means of spreading some of the most fatal and infectious diseases, such as leprosy, syphilis, tetanus, tuberculosis, smallpox and presently AIDS, polio and meningitis. Economic interest is the main reason why no medical breakthroughs exist for the control or elimination of the most common diseases and why these diseases continue like epidemics on a worldwide scale. The pharmaceutical industry withholds public information about the effects and risks of their prescription drugs and vaccines and life-threatening side-effects are omitted or openly denied. Many Blacks in the U.S., like their counterparts throughout Africa and the Diaspora, cannot even afford pharmaceutical drugs to alleviate the symptoms of disease. In healthcare, intellectual property rights have increased the price of pharmaceutical drugs. Generally, the chronic ailments and diseases that affect Afrikans in the Diaspora, i.e. cancer, diabetes, heart disease, obesity, etc. are based on improper diet and lifestyles. By design, Afrika is plagued with natural and unnatural occurrences of communicable, parasitic and infectious diseases, such as AIDS, malaria, polio, etc. With their corresponding vaccinations and pharmaceutical drugs, these diseases are devastating the continent's Black population. The AIDS/Malaria genocide, taking place in Afrika, is painting a clear pattern of death, of cultural, economic and agricultural destruction which will be followed by encroaching Western political, economic and military control. Control over the world’s natural plant resources are also at risk. For the very same economic reasons mentioned above, the pharmaceutical industry has formed an international cartel by the code name "Codex Alimentarius" with the aim to outlaw any health information in connection with vitamins and to limit free access to natural therapies on a worldwide scale. The multinational drug companies are helping to place a ban on natural herbal products as well to monopolize the vitamin and herbal remedies as their limitless source of revenue. In fact, what is already occurring in many developing countries is "biopiracy", where corporations use the folk wisdom of indigenous peoples to locate and understand the use of medicinal plants and then exploit them commercially through patents. From such an act of biopiracy, two drugs derived from the rosy periwinkle (vincristine and vinblastine), earn $100 million annually for Eli Lilly. The plant is indigenous to the rainforest of Madagascar and Madagascar has received nothing in return. These same multinational companies have introduced diseases that can destroy the plants and herbs we use as natural sources of nutrients, so that we can become more dependent on their products. These are the same multinational corporations that have a monopoly on the development and production of genetically modified organisms, pesticides and herbicides, which poison the environment and produce metabolic changes in our foods and in our bodies. Biodiversity is Afrika's richest asset. Traditional knowledge on the properties of plants, seeds, algae and other biological resources is being sought by western scientists for medicinal, agricultural and other purposes. Trade in biological resources is big business today, but the terms are tipped in favour of the multinational corporations and are not in Afrika’s benefit, undermining the collective rights of communities to biodiversity. Since time immemorial, Afrikan people have depended upon free and open access to a rich diversity of biological resources for food, fuel, medicine, shelter, economic security, and the exchange and trade of such resources among themselves. In agriculture, the commercialisation of the seed market, patents on seed, and the introduction of genetic engineering have serious implications for Afrika’s farmers and food security. -38- Traditional African Clinic October 2008 Continued on page 39 Continued from page 38 – The Afrikan Traditional Herbal Research Centre Much of the knowledge on Afrika’s indigenous plant population and their curative powers are from studies mapped and funded by western countries and stored in western information depositories such as PROTA in the Netherlands or from the Medical Research Council in South Africa. There exist over 7000 medicinal plants in Tropical Africa. Although these studies are far from complete, 76 plants indigenous to Uganda and 208 indigenous to East Afrika are listed. Information on indigenous medicinal plants in Uganda needs to be gathered and assembled in a centralised location for use by herbalists and other medical professionals. This will allow local indigenous knowledge to be published and protected and its plant uses, standardised. This rather long introduction, written in 2005 is the introduction text of a proposal Blackherbals presented to several Ugandan government agencies and NGOs such as MPAMBO Multiversity, National Chemotherapeutics Laboratory (NCRL), National Council of Traditional Herbalists Associations (NACOTHA), etc. to establish a school of African Traditional Herbal Medicine. The aim and objectives of our proposal are: • To recapture indigenous Afrikan thought, history, herbal, medicinal and agricultural traditions and all other indigenous knowledge to reeducate our people to Afrikan culture. • To use and integrate this knowledge with technology to develop our nation of people, alleviate poverty and achieve higher levels of selfsufficiency, dignity and self-determination. • To take responsibility for Afrika’s health, wealth and education using Afrikan indigenous knowledge as the foundation for understanding the complex world we live in today. Who we are We are Kiwanuka and Nakato Lewis, husband (retired engineer) and wife (retired research chemist), partners, born in Jamaica and the United States, respectively, descendants of enslaved Afrikans from the Diaspora, standing on the shoulders of our Ancestors. Initially, as RGL Enterprises International Inc., (registered in New York and Toronto, Canada), we created www.Blackherbals.com to address the lack of herbal/nutritional knowledge among Afrikans/Blacks in the Diaspora. With the growth of Western medicine, we discovered that the use of Afrikan herbal medicine and traditional foods known by the enslaved Africans in the Diaspora, such as in the United States, was discouraged and hence, most of that knowledge was lost. Many Afrikan societies throughout the Diaspora however, retained some of their Afrikan traditions, such as the Jamaican Maroons. What we had learned from a previous trip to Uganda in 2004 was that many Ugandans were also in danger of losing their indigenous knowledge and the ability to heal themselves using traditional Afrikan healing methods. Ugandans were told by practitioners of Western medicine that traditional herbal solutions do not work and is considered witchcraft. As a result, there is ample evidence that Ugandans are beginning to suffer the same fate as their brothers and sisters in the Diaspora. What is even more surprising was that many of the herbs which could be used to correct some of the most common ailments of many Ugandans could be found in their own compounds! Meanwhile, multinational pharmaceutical companies were and are documenting Afrikan herbs and plants with the intent of commercially developing and patenting expensive new drugs. As Afrikans, we should take ownership of our ancient knowledge and resources and exercise our intellectual property rights to pass our indigenous knowledge to our descendents for their descendents. The Afrikan’s knowledge of herbal medicine, both on the continent and in the Diaspora, is far older, than any indigenous group on the planet. But, there are not many books for the world to see on Afrikan Traditional Medicine (ATM). We suggested that Uganda can become a world model by taking the initiative and developing an independent and alternative health care system based primarily but not solely upon their indigenous knowledge of herbs, food and plants. At that time, however, we were told by everyone that Uganda lacked the capacity, the infrastructure and the resources for these types of endeavors. So we elected to start our own clinic - The African Traditional Herbal Research Clinic/Centre - to learn first-hand about African herbal-based medicine, traditional herbs and their uses, to conduct clinical research on herbal plants for use in our herbal formulations that could positively impact the health of Afrikan people everywhere and finally to learn about African Spirituality and its integration in holistic healing. RGL Enterprises Intl/Blackherbals at the Source of the Nile UG Ltd. is registered in Uganda since November 2005. In February 2006, The African Traditional Herbal Research Clinic/Centre was established with the initial help of NACOTHA, of which Kiwanuka Lewis is a member and the clinic is registered as a traditional herbal association. Both Kiwanuka and Nakato are registered Continued on page 40 -39- Traditional African Clinic October 2008 Continued from page 37 – The Afrikan Traditional Herbal Research Centre with the Ugandan Government as traditional herbalists. Our first two years was devoted to the research and development of herbal formulas, in a clinical setting, to address the health problems of continental Afrikans suffering from traditional African diseases and chronic diseases acquired from the adoption of Western culture. Many of the local herbs have been tested in the treatment of various symptoms at our research centre. The results are very, very encouraging. Our BHSN formulas contain selected wild-crafted herbs gathered and collected from historically traditional sites throughout Uganda. The herbs we collect and use are traditional organic, free of all pesticides, herbicides, chemical inputs and when necessary produced using traditional agricultural methods. We have established good working contacts with other traditional herbal groups in Central Uganda (Walussi Mountain, PROMETRA) and with Kasese/Rwenzori area in western Uganda, (KADDENTHCA), enabling us to learn from them as they are learning from us. Recently, our contacts have extended to groups in eastern Uganda as well as to groups in the war-torn north. We have attended various workshops and symposia, such as NCRL, Malaria Consortium, NAPRECA, Uganda Industrial Research Institute, Uganda Historical Memory and Reconciliation Council, Inter Cultural Union of Uganda, Makerere University and Marcus Garvey Pan Afrikan Institute in Mbale. At MPAI, Kiwanuka is a research fellow and Nakato is on the Board of Directors. Kiwanuka is also an executive Board Member of the Walussi Spiritualists Committee. Walussi Mountain in central Uganda is our village. ATHR Clinic With information gathered from a community needs survey conducted by BHSN in Bukoto Parish, Kampala in October 2005, we identified 12 immediate diseases affecting area residents. Therefore, our efforts were concentrated on herbal medicines for these disorders. Our research uncovered many existing traditional African herbal formulas. With respect to usage, standardization, quality control and dosage, we have sought to refined them and to created and develop new ones as well. Our aim is to use this concept throughout various communities in Uganda to effectively fight diseases at home, the natural way. We have been asked to take our concept abroad to other parts of the African continent and to the Diaspora where our people are suffering from the same diseases, only in larger numbers. Since then, we have provided treatment for over 60 diseases, symptoms and conditions with varying degrees of success. Our present patient load is over 300 people and new patients are arriving everyday. Most of our patients have multiple health problems. As required by our protocol, none of our patients take western pharmaceuticals. Some of the services we offer are noninvasive treatments for: 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. 25. AIDS (Herbal Antiviral) Malaria Diarrhea/Constipation Heart problems (pressure, circulation, strokes) Diabetes Sexual Transmitted diseases Respiratory ailments (asthma, colds and TB) Ulcers and other Digestive disorders Skin diseases and rashes Arthritis and Rheumatism Reproductive problems -Fertility (Men and Women) Tumours and Growths Sickle Cell Anemia Central Nervous System (Epilepsy) Cancer Paralysis Gout Weight Loss Urinary Tract Infections Hepatitis Detoxification Energy Tonics Muscle Pain Feminine Problems Addictions Over 35% of our patients were presented to us with malaria symptoms. Many were previously diagnosed with recurring malaria and laboratory tests continue to show parasites in their blood even after taking western prescription medicines. Our treatment consists of only three bottles of Blackherbals’ Malaria Mix (without artemesia) taken over a period of 4-6 weeks. Laboratory testing of our patients have confirmed the absence of these parasites after treatment and many of our patients have remained parasite-free for nearly two years and still counting. Our formula has been effective in the treatment of malaria even during the onset of symptoms as well as in the prevention of disease. Therefore, it is very puzzling for us and difficult to accept that there can be a malaria epidemic in Uganda when herbal medicine is equally if not more effective than western pharmaceuticals. Moreover, we have able to increase the CD-4 count of HIV/Aids patients using herbal detoxification and herbal antiviral formulas. Thus we have been able to effectively -40- Traditional African Clinic October 2008 Continued on page 39 Continued from page 38 – The Afrikan Traditional Herbal Research Centre treat both malaria and HIV patients while reducing the side effects associated with taking western pharmaceuticals for HIV/Aids and malaria. In addition, there is no shortage of the herbal medicine since we only use local herbs. Fifty-four percent of our patients present themselves with digestive problems, namely ulcers, gastritis and gout. These disorders are generally associated with Ugandan diet, the love for milk, meat and alcohol. We have been able to completely eliminate gout, heal ulcers and gastrointestinal problems even in patients with advanced symptoms. Our herbal formula for diabetes, ‘DIA-B’ has been effective in controlling blood sugar levels to the point that one only has to monitor oneself and make the necessary corrections through diet and exercise to maintain control, thus eliminating the need for constant medication. Thirty-one per cent of our patients suffer from high blood pressure and other pressure-related problems. One of the major causes is the Ugandan love for salt and salty food. This is a common problem not just for Ugandans but Black people worldwide. Along with dietary changes, Blackherbals ‘BP’ has been very successful in maintaining normal blood pressure levels without the side effects usually experience with pharmaceuticals. Incorporating the use of spices in one’s food has gone far to help our patients alleviate the salt from their diet. Some of our patients, who have been on blood pressure medication for years, use only herbal medicine to control their blood pressure. Forty percent of our clients have some type of respiratory disorders. In the dry season, Uganda can be very dusty and many people are affected, developing flu-like symptoms and cough. Patients suffering from asthma, bronchitis and pneumonia have found substantial relief taking our respiratory mixes. Thirty-five per cent of patients are women complaining of female problems to include painful menstruation fibroid tumours and blocked tubes, some requiring surgery. We have been successful in reducing the size of the tumours, saving many from surgery. We have had 100% success rate with goiters and some hernias. All of our patients are detoxified prior to or during treatment. For some, detoxification is all that is required for the symptoms to disappear. We also provide patient counseling on their dietary habits and what they can do to improve their health naturally. We provide information in the form of newsletters and articles to educate and enlighten our patients on their conditions. We believe that an informed patient is one who will begin to take responsibility for his or her health, because ultimately that is where it belongs. We train our employees to develop proper work ethics, to display honesty, integrity and accountability and transparency in all endeavors as well as pride in themselves and the work they do. This is our biggest challenge. The Way Forward For the past six months we have been standardizing our formulations to determine dosage, shelf life and efficacy in concordance with the standards set forth by the National Chemotherapeutics Research Laboratory, the National Drug Authority and the Uganda National Bureau of Standards. In the coming months, our formulas will be presented to these government agencies for formal registration and approval. We are proud and happy to say we have made some significant achievements and contributions. Our new product line at BHSN reflect many Afrikan traditional plant materials whose uses are documented throughout the Afrikan continent, but have never been actively promoted. In conjunction with MPAI, we are helping to establish a School of African Traditional Medicine over the next several years. Blackherbals has introduced a new service to link our clinic operations with our internet storefront. We do custom made formulations for off-site patients in health crisis who do not have access to herbal practitioners. What we require is a letter or email stating the problem, your symptoms, your diet, current prescriptions and any diagnostic data provided by doctors, hospitals, etc. This information is used to set up your patient chart and to determine the individual efficacy and effectiveness of our formulas. We formulate herbal solutions for various health problems and symptoms, that in many cases can be just as effective in treating the illness as prescription medicines, which in many cases can become resistant to the disease, will only address one issue of the problem, or may be too toxic. A custom-made diet is detailed for the patient because the Afrikan diet is essential to our good health and recuperation. The cost of our formulations is dependent upon the type of medical problems, quantity and availability of required herbs, number of formulations needed and duration of treatment. Our prices are very affordable. Please email us clinic@blackherbals.com for more details. We look forward to hearing from you soon. We invite you also to visit us online at www.blackherbals.com to learn more about us and our concerns on the survival of Black people. In our own small way, we are helping to bring about a “Black Awakening” not just with words but through active participation in this historical process. -41- Traditional African Clinic October 2008 ☻☻☻☻☻☻ Continued from page 36 - Africa: Researchers Record Major Breakthrough The Australian team developed mutant strains of P. falciparum, each lacking one of 83 genes known or predicted to play a role in the red cell remodeling process. Systematically testing each one, they were able to show that eight proteins were involved in the production of the key glue-like substance. Removing just one of these proteins stopped the infected cells from attaching themselves to the walls of blood vessels, the report revealed. Professor Alan Cowman, a member of the research team at the Walter and Eliza Hall Institute of Medical Research, said targeting the protein with drugs, or possibly a vaccine, could be key to fighting malaria. "If we block the stickiness, we essentially block the virulence or the capacity of the parasite to cause disease," he said. Malaria is preventable and curable, but can be fatal if not treated promptly. The disease kills more than a million people each year. Many of the victims are young children in sub-Saharan Africa. Available statistics indicate that one out of every five Nigerian children will die before their fifth birthday, with malaria alone being responsible for one quarter of these deaths. Malaria is said to be responsible for an estimated 30 per cent of deaths among children, 11 per cent among pregnant women and 80 per cent of diseases in reported cases in health facilities. It is certainly the leading cause of morbidity and mortality in the country. Records also show that 50 per cent of Nigeria's population suffers from, at least, one episode of malaria attack each year. The disease accounts for over 45 per cent of all outpatient visits. The Federal Government spends millions annually on awareness campaigns and provides malaria control measures, which involves programmes such as the Roll Back Malaria Initiative, where special insecticidetreated bed-nets are produced and distributed to the people, especially nursing mothers. Various countries and international organisations such as Japan and the World Health Organisation (WHO) are also collaborating with the country in the fight against her 'biggest' killer. In the country, malaria is directly or remotely responsible for the loss of millions of productive hours, resulting in colossal reduction in individual and collective productivity. The Kano State Commissioner for Health, Malama Aisha Ishiaku, recently stated that the malaria scourge accounts for an annual economic burden of about N132 billion in Nigeria. Reports also revealed that in Africa, malaria accounts for 10 per cent of the continent's disease burden as well as the $12 billion yearly lost in productivity. Globally, about 40 per cent of world population (2.4 billion) is known to be at risk. An estimated 300-500 million cases of malaria occur globally every year. http://allafrica.com/stories/200807150155.html ☻☻☻☻☻☻ HIV ‘Hides from Drugs for Years’ BBC March 16, 2008 HIV can survive the apparently effective onslaught of antiretroviral drugs for years by hiding away in the body’s cells, research shows. The US National Cancer Institute found low levels of dormant HIV in patients seven years after they started – and responded well to - standard therapy. The finding confirms patients must take drugs indefinitely, and that any break runs the risk of rekindling infection. The study features in Proceedings of the National Academy of sciences. People with HIV need to take treatment indefinitely because current drugs cannot reach this pool of dormant virus. The researchers followed 40 patients infected with HIV for seven years. Doctors do not usually record infection levels once the number of HIV particles falls below 50 per milliliters of blood. However, the NCI team used highly sensitive equipment to measure infection levels below this threshold. They found that the virus was still present at low levels in 77% of the patients. The research suggests that although potent antiretroviral therapy can suppress HIV infection to almost undetectable levels, it cannot eradicate the virus. The researchers said that even though levels of the virus that remain are low, they are high enough to rekindle infection if treatment is interrupted. The risk of infecting others is low, but cannot be ruled out. They believe HIV may be harboured by CD-4+ cells, which parlay a role in the immune system. Continued on page 43 -42- Traditional African Clinic October 2008 Continued from page 44- HIV hides from Drugs for Years These cells are most likely infected before therapy was initiated and the amount of virus they produce is small. Researcher Dr Sarah Palmer said: “It is extremely important that new drugs are developed to eradicate HIV infection as the side effects associated with long term HIV treatment can be severe. She also warned that failing to take prescribed medication raised the risk that HIV could begin to develop resistance, rendering future treatment less effective. ☻☻☻☻☻☻ Only 5% Rural Children Access ARVs – Study David Mafabi provide services for the children visited in eastern Uganda, less than one per cent of the children access ARVs. Dr Elyanu said in Budadiri health centre IV in Sironko District and Amuria health centre IV in Amuria District, although 85 and 94 children infected with HIV/Aids respectively have been registered to get ARVs, only one is accessing it at each of the centres. Dr Elyanu said at Budaka health centre IV and Pallisa Hospital, only four children are accessing ARVs. He said les than three children are accessing ARVs in Kumi, Bukedea, Bukwo, Kapchorwa, Kaberamaido, Katakwi, Butaleja, Bududa and Manafwa. ☻☻☻☻☻☻ ARVs can double Patients’ Lives - Study Kakaire Kirunda Daily Monitor March 26, 2008 Only 17 per cent of the children infected with HIV/Aids in Uganda access anti-retroviral drugs. Of these, less than five per cent are from rural areas, according to research done by Baylor College of Medicine Children’s Foundation-Uganda Most of the 83 per cent infected children in rural areas do not access treatment and usually die, Baylor College of Medicine Children’s Foundation Uganda [BCMCFU] regional coordinator Dr Peter Elyanu says. BCMCF-U is an indigenous, child focused NGO specialized in child HIV/Aids and affiliated to the Baylor International Paediatric Aids Initiative (Bipai). Dr Elyanu, a paediatrician, was last Wednesday addressing medical staff, district leaders, and representatives of NGOs involved in the fight against HIV/Aids in Pallisa town during a conference to seek ways of increasing child HIV/aids services in the region. He said due to lack of access to ARVs, about 75 per cent of children infected with HIV/Aids die before the age of five. Dr Elyanu said whereas currently Uganda has close to 140,000 children living with HIV/Aids and another 25,000 continue to be infected annually, access to paediatric HIV/Aids services and ARTs have remained limited to the central region thereby leaving many of the infected children in rural areas dying within the fifth year. He said, in most government health centres meant to Daily Monitor July 31, 2008 People using antiretroviral (ARV) drugs can now expect to live into their 60s and beyond, if finds from an international study are anything to go by. A report published in the Lancet medical journal indicates people living with HIV/Aids could have ARVs prolong their lives by anywhere between 30 and 50 years, meaning a person that embarks on ARV therapy at 20 could live up to 70 years. Analysing 18,587 (1996-99), 13,914 (2000-02) and 10,584 (2003-05) patients on combination antiretroviral therapy (ART), researchers from Canada and the United Kingdom sought to compare changes in mortality and life expectancy among HIV-positive individuals. Results from 14 studies in that period show that Aidsrelated deaths decreased progressively through the years, accounting for a 40 percent reduction by 2005. Published in the July 26 edition of the Lancet medical journal, the study showed that an individual starting successful HIV treatment aged 20 would be expected to live to be 63, and that a patient initiating an anti-HIV drugs regimen aged 35 could live to the age of 67. Since the 1966 introduction of antiretroviral therapy, combination therapy regimen have become more effective, better tolerated and have been simplified in terms of dosing. The researchers also found that starting treatment with a CD4 cell count above 200 would mean that a person aged 20 could expect to live to be 70, and that a 35-year-old could survive into their 72nd year. -43- Traditional African Clinic October 2008 Continued on page 44 Continued from page 45 – ARVs Can Double Patient Lives A CD4 count is used to assess the immune status of HIV infected persons. In Uganda, there are currently about 132,000 people on antiretroviral therapy, yet nearly 300,000 require the drugs. However, the government recently allocated Shs60 billion to the health sector for the procurement of ARVs, a move likely to bring another 150,000 persons living with HIV on treatment. Uganda has set a target of putting 263,000 people on treatment by 2012, and 342,000 by 2020. But this raises questions on sustainability, as 95 per cent of the ARV programme is currently donor supported, mainly by the American-funded President’s Emergency Plan for Aids Relief (Pepfar) initiative. ☻☻☻☻☻☻ Drug Factories SubStandard By Conan Businge New Vision (Kampala) 18 July 2008 THE majority of drug manufacturing companies in Uganda do not meet operational standards, according to a new survey. A survey by the National Drug Authority revealed that several companies will be closed soon, after their grading is completed. The companies were not named. The report was presented at the authority's annual general meeting at Protea Hotel in Kampala on Thursday. It noted that most companies do not meet required minimum production standards. It also found unsanitary protective uniforms, change rooms, production rooms, stores, corridors and wash areas for manufacturing vessels." "Half of the manufacturing companies had problems with cleaning sanitary premises," said Nasser Mbaziira, the eastern regional drug inspector, "A number of them have procedure guidelines, but no records; and the reverse was true for others." He added that there were also anomalies in the flow of the production process. The inspectors explained that there should be a specific flow of the production process to avoid contamination and back flows. "Much as there is improvement in documentation of manufacturers' activities, the majority of them do not record the production process," said the report. It also noted that half the companies did not have internal audit systems and there was little input from the managers in the production process. Despite the shortcomings, the companies had hand washing facilities, ongoing installations of air-conditioning systems and quality control labs. Mbaziira said the firms would be graded in five categories depending on their performance. "The worst ones with critical working conditions will have their certificates and licenses withdrawn. They will also be instantly closed." Copies of the survey's highlights, which were given to the participants, were later withdrawn after complaints from some manufacturers who wanted the results to remain confidential. "This is unfair to us. How are we going to convince exporters that our products are of good quality? You should have addressed the press, exporters and manufacturers differently," retorted one as several participants nodded in approval. However, the authority's chief inspector, Kate Kikule, said: "There is nothing to hide. In this way we can build our local producers by improving their products' quality. All drugs are inspected before getting to the market. "Only those that meet the standard are distributed to the public." NDA chief Apollo Muhairwe stressed that the "inspections were done to develop the local drug manufacturing industry." http://allafrica.com/stories/200807210123.html ☻☻☻☻☻☻ CDC: 1.1 million Americans have AIDS Virus Population living with HIV grows as more become infected, survive longer October 2, 2008 WASHINGTON - A new estimate of how many Americans have the AIDS virus puts the number at about 1.1 million, the U.S. Centers for Disease Control and Prevention said on Thursday. The CDC numbers, based on 2006 data, show the population living with HIV is growing as people become newly infected and as more patients survive thanks to HIV drugs. The report also suggests that past estimates that more than 1 million Americans were living with HIV overstated the -44- Traditional African Clinic October 2008 Continued on page 45 Continued from page 44 – CC: 1.1 M Americans have AIDS Virus actual total number of people with HIV infections at the time. The agency used different methods than it has in the past to calculate the number. Its most recent nationwide estimate of 1 million had been given for 2003, and using the new methods the CDC figured that 994,000 were living with HIV that year. "These data really show the continued impact that the epidemic is having on Americans, and they really reinforce the severe toll that is experienced in multiple communities," the CDC's Richard Wolitski said in a telephone interview. The CDC report reinforced previous findings that the epidemic disproportionately affects blacks of both sexes as well as gay and bisexual men. As the number of people living with HIV grows, so does the cost of providing medical services to this population and the burden on the U.S. health care system, Wolitski said. The CDC estimated that about one in five — 232,700 of the 1.1 million people infected with the human immunodeficiency virus that causes AIDS — did not know they were infected. The total U.S. population is 300 million. "We're not going to be able to treat our way out of this epidemic. We need to have strong prevention programs so we can prevent these infections from occurring in the first place," said Wolitski, acting chief of the CDC's HIV/AIDS prevention division. Men made up three quarters of people with HIV infections. The CDC previously reported that more people are becoming infected each year than previously estimated, with 56,300 new HIV infections in the United States in 2006. Previous estimates put the number of new infections at about 40,000 a year. Of all the people infected with HIV, 48 percent were men who have sex with men, the CDC said. While male-to-male sexual contact was the leading cause of HIV infections, heterosexual sex — mostly women having sex with men who are injection drug users — accounted for 28 percent of HIV-infected people. Injection drug use, which spreads the blood-borne virus via contaminated needles, contributed 19 percent of the HIV cases. Blacks make up 12 percent of the overall population but accounted for 46 percent of those infected with HIV (510,100 people). About 35 percent of those with HIV were white and 18 percent were Hispanic, according to the CDC. Black women were nearly 18 times more likely than white women to be infected with HIV, while black men were six times more likely than white men, the CDC said. Hispanics were 2.6 times more likely than whites to be infected. In 2006, about 14,000 Americans died of AIDS. At the end of 2006, the disease had killed nearly 546,000 Americans since being first recognized in the early 1980s. To make the new estimates, the CDC used information on new HIV diagnoses taken from 40 states with the best data and AIDS diagnoses and deaths taken from all 50 states, as well as a statistical method called "back-calculation." Globally, 33 million people have HIV and 25 million have died of it. http://www.msnbc.msn.com/id/26993069 ☻☻☻☻☻☻ HIV Spread Still High Despite Fall in Infection Evelyn Lirriin Saturday Monitor August 2, 2008 Uganda is one of the countries where a significant prevention of new infections of HIV has been registered, the latest report by the Joint United Nations Programme on HIV indicates. The report released on July 29 says that much of the dramatic declines have been as a result of change in sexual behaviour. “In a number of heavily affected countries such as Kenya, Rwanda, Uganda and Zimbabwe, dramatic changes in sexual behaviour have been accompanied by declines in the number of new infections,” the report says. It says that a decline in new infections in these countries has contributed to the global stabilization of people infected by the virus since the late 1990s. According to the report, some of the factors contributing to the decline in sexual behaviour are the increased use of condoms and abstinence from [sex] until later years. The report warns that even with the registered prevention of new infections, there is still a long way before the promise of an Aids free generation is fulfilled. It says that progress is still uneven across countries, and the epidemics future still uncertain. -45- Traditional African Clinic October 2008 Continued on page 46 Continued from page 45 – HIV Spread Still High Despite Fall in Infection Uganda has been promoting the ABC – Abstinence, Be Faithful and use a Condom approach for HIV prevention. This enabled the country to reduce its national HIV prevalence from about 30 per cent in the early years of the epidemic to about 6.4 per cent to date. However, recent trends indicate that since 2000, the prevalence has stagnated. This latest comprehensive report published by Unaids is based on progress review reports from 147 countries globally as part of efforts to implement the 2001 declaration of commitments on HIV. HIV Infection Rate High Among Forces By Rehema Aanyu New Vision (Kampala) 17 July 2008 The rate of new HIV infection is high among the armed forces compared to the civilian population, the director general of the Uganda AIDS Commission has said. Dr. Kihumuro Apuuli noted that the infection rates were two to five times higher among the forces than in the whole population. The report also says that increased financing for HIV programmes, especially in low income countries including Uganda has contributed to lowering prevalence and preventing new infections. "For every two people put on anti-retroviral (ARV) treatment, five more are infected. It is like chasing a mirage." The Director General of the Uganda Aids Commission, Dr Kihumuro Apuuli, said in Uganda’s Progress He observed that the armed forces were also at increased risk of contracting and spreading HIV due to their mobility. Report that some of the factors driving the epidemic include behavioural, social, cultural, economic and geographic factors like poverty and early marriage. Apuuli was on Tuesday addressing the army, the Police and Prisons Service chiefs at the Kampala Protea Hotel. Dr Apuuli said that new infections are found highest among cohabiting married or widowed people. This group category, he said contribute to 42 per cent of the new infections, conventional sex contributes 22 per cent, mother to child transmission 21 per cent, while casual sex contribute to 14 per cent of new infections. According to Dr Apuuli, currently the HIV prevalence rate is 6.4 percent, with percentages higher in the urban areas at 10.1 per cent while in the rural areas prevalence stands at 5.7 per cent. In a press statement, the executive Director of Unaids, Dr Peter Piot said the positive progress should be sustained. “Gains in saving lives by preventing new infections and providing treatment to people living with HIV must be sustained over the long term,” he said. “Short term gains should serve as a platform for reinvigorating combination HIV prevention and treatment efforts and not spur complacency,” Dr Piot added. ☻☻☻☻☻☻ Daily Monitor Brief - May 8, 2008 At least 27,000 babies in Uganda are born with HIV/Aids every year, according to new statistics released by the Parliamentary Committee on HIV/Aids. Less than 20% of HIV positive pregnant women have access interventions to prevent mother to child infections. He attributed the new infections to increased interaction between combatants and civilians, and rise in commercial sex. Apuuli also cited decreased availability of health services related to sexually transmitted infections and the lack of adequate knowledge and means to prevent transmission. The armed forces should incorporate HIV/AIDS interventions in their programmes and counter stigmatisation of victims, Apuuli suggested. "The armed forces must help in building bridges between communities and vulnerable groups to make their lives easier." He also called for more funding to expand access to antiretroviral therapy as well as medicines to treat opportunistic infections and other sexually transmitted diseases. The director of HIV/AIDS interventions in the army, Lt. Col. Stephen Kusasira, said the disease was the main cause of death in the force. He said they were incorporating sensitisation on the pandemic in all command duties and training. The meeting was organised by the Community Health and Information Network. ☻☻☻☻☻☻ -46- Traditional African Clinic October 2008 ☻☻☻☻☻☻ Circumcision may not reduce gay male HIV risk Study: No clear proof procedure protects men who are intimate with guys October 7, 2008 WASHINGTON - There is not enough evidence to say circumcision protects men from getting the AIDS virus during sex with other men even as studies show it protects them when having sex with women, U.S. researchers said on Tuesday. A review of 15 studies involving 53,567 gay and bisexual men in the United States, Britain, Canada, Australia, India, Taiwan, Peru and the Netherlands failed to show a clear benefit for those who were circumcised, researchers from the U.S. government's Centers for Disease Control and Prevention said. Circumcised men infected with the HIV, than those finding was not researchers said. were 14 percent less likely to be human immunodeficiency virus, or who were uncircumcised, but the statistically significant, the CDC "You can't necessarily say with confidence that we're seeing a true effect there," said the CDC's Gregorio Millett, who led the study that appeared in the Journal of the American Medical Association. "Overall, we're not finding a protective effect associated with circumcision for gay and bisexual men," Millett said in a telephone interview. Studies involving men in Africa, where the AIDS epidemic is primarily spread by sex between men and women, showed that male circumcision halved the risk of female-to-male HIV infection. Experts say this reduced HIV risk may be because cells on the inside of the foreskin, the part of the penis cut off in circumcision, are especially susceptible to HIV infection. The virus also may survive better in a warm, wet environment like that found beneath the foreskin. But whether circumcision might lower the risk of HIV infection in sex between men had remained unclear. Gay and bisexual men play a much larger role in AIDS in many countries outside of Africa, the epidemic's epicenter. For example, the CDC last week said 48 percent of the 1.1 million Americans infected with HIV are men who have sex with men. More than three-quarters of U.S. men are circumcised. "We really cannot recommend overall male circum- cision as a strategy for men who have sex with men in the United States," Millett said. The CDC's Dr. Peter Kilmarx, who was not involved in the research, said the agency is preparing formal recommendations on circumcision in the United States, with a draft due to be made public early next year. Millett said there are signs circumcision might protect certain gay and bisexual men depending on sexual practices. The virus can be transmitted through blood or semen. Studies in Australia and Peru showed that men who engaged in insertive anal sex only and were not being penetrated by male sex partners got a significant protective effect from HIV infection from being circumcised, Millett said. "Of course, if you're being penetrated by a partner during sex, you being circumcised is not going to protect you from HIV infection," Millett said. Millett said two U.S. studies and one in Peru conducted before the introduction in 1996 of combination drug treatment for HIV infections, called highly active antiretroviral therapy, or HAART, showed that circumcised men were 53 percent less likely to be infected with HIV than uncircumcised men. He said it is possible that since the advent of HAART, which helped turn HIV infection into a chronic disease rather than a death sentence for many people, some gay and bisexual men may have felt freer to engage in risky sexual practices. http://www.msnbc.msn.com/id/27074050/ ☻☻☻☻☻☻ The Other Face of Circumcision in HIV War Michael Bahinyoza HIV Prevention Daily Monitor August 1, 2008 The Geneva-based World Health Organisation has reportedly, over the last couple of months been leading UN Agencies (UNAIDS), UNICEF, UNFPA) to support particularly African countries to develop male circumcision policies and strategies in the broader/comprehensive HIV prevention strategy. The follows results from the three Randomised Controlled Trials (RCTs) undertaken in Kisumu (Kenya), Rakai (Uganda), and Orange Farm (South Africa) showing that male circumcision could reduce the risk of heter- -47- Traditional African Clinic October 2008 Continued on page 48 Continued from page 47 – The Other Face of Circumcision viral load and thus infectivity to the female partner. osexually acquired HIV infection in men by about 60 per cent. For now, it may be wise for our own Ministry of Health, the medical fraternity and the public to be cautious and not to be overwhelmed by the hyperbolic’ promotion of male circumcision in HIV prevention. According to media reports, Rwanda has already rolled out male circumcision in the military, a country where ironically, circumcised men have a higher rate of HIV than ‘intact’ men. (www.circumcisionandHIV.com) A colleague told me last week, seven of his friends (all of them single) had been circumcised in this ended month of July and that the RCT findings had majorly influenced their decision. It is worth noting that because of information deficiency and other challenges, there have been a number of exaggerated claims made for the reported efficacy of male circumcision in preventing HIV infection. Many people are not even aware that the results from the above mentioned randomized Controlled Trials are about prevention of female-to-male HIV infection. Secondly, not many young people (and probably adults as well) seem aware that the trial results clearly indicated that male circumcision reduces the risk infection. Unfortunately, many young male adolescents and some men prefer reading or hearing reducing the risk as eliminating the risk. Undoubtedly, there is ‘a heaven of difference’ between risk reduction and risk elimination and hopefully, this can be well grasped in the preventive campaign against HIV/Aids. Reputable senior research fellows, Garry Dowsett and Murray Coach, from Australia suggest in their findings; “The use of male circumcision in preventing HIV infection” that the results of the three RCTs contain exaggerated claims. In his work; “The Demonisation of the Foreskin and the Rise of Circumcision in Britain.” Darby RJL, too brings to the fore what he considers information that the respective supervisors of the three RCTs should not have ignored. Apparently it turns out that all the three RCTs were terminated early, arguably before the incidence of HIV infection in the circumcised males caught up with the incidence of infection in the non-circumcised males. It is therefore highly probably that non-circumcised got infected more quickly than their circumcised friends because the circumcised males required a period of abstinence after circumcision, suggesting, among other things, likely that if the studies had continued as initially scheduled, the difference in infection incidence between the two groups males would have been small. As has been noted by our own Ministry of Health, male circumcision does not protect women. Since viral load is the cardinal predictor of the risk of HIV transmission, male circumcision would not reduce the Pre-marital chastity and fidelity, nurtured and supported by needed life skills within viable and dynamic support groups, remain time-tested HIV/AID preventive weaponry as the infected and affected are given needed care and support. ☻☻☻☻☻☻ Breakthrough Reported in Malaria Drug Trial Kakaire Kirunda Daily Monitor May 1, 2008 Canadian scientists working with Ugandans at Makerere University have reported that their novel drug candidates to treat malaria have demonstrated good safety in their first toxicity tests in animals. This was announced on Monay in a press release by the Canada-based Upstream Biosciences Inc. The Institute was founded in 2004 in the Canadian province of British Columbia. “Researchers reported that Upstream’s anti-malarial candidates were well tolerated, with no signs of serious toxicity at likely healing dosages,” the release reads in part. According to the researchers, activity in this range in a new class of anti-malarial drugs has the potential to represent an important advance in the treatment of a resistant form of the disease. The release said the new data represents the third set of positive toxicity results in animals obtained by researchers at Makerere University for Upstream’s drug candidates for malaria, trypanosomiasis and leishmaniasis, all diseases caused by related parasites. “These first positive toxicity results in animals for our anti-malarial candidates mark an important step in our programmed to develop safe and effective drugs to fight this pervasive condition,” Mr. Joel Bellenson, CEO Upstream was quoted as saying. However, in a follow-up interview with Daily Monitor, Mr Bellenson said researchers can now move on to testing the drugs in sick animals,” and we know how high a dosage ceiling we can use for this testing.” -48- Traditional African Clinic October 2008 Continued on page 49 Continued from page 47 – Breakthrough Reported in Malaria Drug Trial Asked how soon human trials would begin, he said it was hard to make precise predictions about the timing of trials. He added: “Drug development has several stages and sometimes requires taking one step back to make two steps forward. When we get the animal efficacy data, it will tell us whether we need to use our artificial intelligence software to make the drugs more potent or less toxic.” Mr. Bellenson explained that the current malarial drugs have a similar mode of action and the parasites become resistant to chemicals related to these older drugs quite easily. “Our compounds are a completely different chemical structure and are therefore likely to work by blocking different proteins activities,” he added. “In addition, our compounds may have another advantage to work against sleeping sickness, Nagana and kala azar as well as malaria. This would simplify drug stocking logistics and administration to sick patients.” Malaria is the leading cause of illness and death in Uganda, accounting for 25-40 per cent of all outpatient visits at healthcare facilities. Up to 20 per cent of all hospital admissions and 15 per cent of in-patient deaths are due to malaria. ☻☻☻☻☻☻ Farmers Reap Fortunes of Malaria Treatment Godwin Muhwezi-Bonge Daily Monitor March 4, 2008 Mr. John Tabaro, an elderly farmer in Kabale District who has tilled the land for years growing mainly sorghum made his first Shs2 million last year thanks to a “little-known” crop Sweet Wormwood whose scientific name is Artemsia annua. “I made about Shs2 million after three months of growing [it], I had never made so much money before [and now] I managed to take my children to school and all I think of is more and more artemesia,” he said gleefully. Such is the reception the alien crop has received in an area with no tradition of growing cash crops that after three seasons of uninterrupted cash flow, farmers are considering replacing of traditional food crops with the quick maturing artemesia, a crop used in the production of artemesinin - an ingredient in the manufacture of antimalaria drugs such as Coartem, and Artemether. “I have so far given up on growing sorghum, a traditional crop regarded highly in the area. “I prefer Artemesia because it matures faster [3 months] and gives higher returns compared to sorghum that takes seven months,” he said. Two years ago, farmers like Mr. Tabaro were hard to find. “People were at first reluctant to take on the crop because of the bad experience they had had with the now defunct Agro Management [a company that introduced pyrethrum growing in the area],” Mr Cleth Rugwiza, the extension officer of Aflo Alpine Pharma Ltd (AAPL), said. Introduced in 2005, artemesia was not well received as farmers remained reluctant to hurriedly replace their food crops with the untested cash crop on fragmented pieces of land. When the pioneers registered successes, Mr Rugwiza said, more farmers then clamoured for more seedlings from extension agents. Outgrowers have since grown from 350 farmers when the crop was first introduced to more than 12,000 farmers to date. “We did a lot of work to diminish the negative experience through sensitization in churches, and public gatherings,” he said. Mr. Aggrey Bitungukye, another farmer, said:” At first, I thought a kilogramme of dried leaves was difficult to raise but when I managed to raise about 220 kilograms from my piece of land, I picked up even more interest.” Income Boost Persuaded by the need to diversify incomes of subsistence farmers in Kabale, Aflo Alpine Pharma Limited, introduced the cultivation of a locally grown, affordable anti-malarial treatments, for distribution in local, regional, and international markets. “Kabale was chosen for its alpine climate akin to that of Vietnam and India where the plant is mainly grown,” Mr Rugwiza said. Chloroquine and quinine-based derivatives have long been used in the treatment of malaria in sub-Saharan Africa, where the disease kills about 3,000 per day. However, patients’ increasing resistance to traditional anti-malarial drugs, and the need to stem off malarial deaths has given birth to a new line of treatment in Artemesinin Combination Therapy, of which artemesinia extracted from Artemesia annua forms a vital component. -49- Traditional African Clinic October 2008 Continued on page 51 NDA to Licence Herbalists, Regulate Food Kayinga said he had reported to the resident district commissioner. He noted that half of the healers in Masaka were from Tanzania, Burundi and the DR Congo. Herbert Mugagga "We are planning a major operation against illegal healers. We expelled the Maasai from Kenya, who had flocked the region, because of their dubious characters," said Kayinga. Daily Monitor November 19, 2007 The National Drug Authority will start licensing herbalists in the country to ease monitoring. This was disclosed by Dr Josephine Nanyanzi, the Authority’s Inspector of Drugs in an interview with Daily Monitor last week. Dr. Nanyanzi said the institution is currently holding consultative meetings with herbalists and at the same time sensitizing them to come up with appropriate guidelines. He said the move aims to ensure that premises where herbal medicines are stored or sold are suitable for the purpose. “We are mandated to ensure that the available drugs are of good quality and best of the public. ☻☻☻☻☻☻ Policy to Regulate Herbalists in Offing "But we still have a problem with the Tanzanians. These illegal healers sexually exploit women clients, exposing them to HIV/AIDS." The southern regional Police chief, Andrew Sorowen, urged immigration officials to stop foreign healers from entering the country illegally. He noted that local leaders were no longer crosschecking the documents of new people coming to reside in their areas. "The LCs should check for stamped letters from their counterparts where the new residents originate because we may end up harbouring criminals." Sorowen blamed child sacrifice on illegal traditional healers. ☻☻☻☻☻☻ Tanzanians kill Albinos for Luck Daily Monitor November 11, 2007 BBC, Tanzania April 4, 2008 Government has drafted a policy to regulate operations of traditional healers. “If passed, the policy would create an enabling environment for the full and suitable utilization of traditional and complementary medicine in addressing some of the challenges facing the natural healthcare system,” said Mr. Franklin Nsubuga Muyonjo, a ministry of health consultant. Tanzania’s President Jakaya Kikwete has ordered a crackdown on witchdoctors who use body parts from albinos in magic potions to allegedly bring people good luck or fortune. ☻☻☻☻☻☻ Uganda: 23,000 Illegal Healers in Masaka Dismus Buregyeya New Vision (Kampala) 16 July 2008 A total of 23,115 traditional healers in Masaka are not registered, according to the district traditional healers and herbalists' association. The chairman, Ssalongo Kayinga, told The New Vision on Tuesday that Nyendo Division alone had 343 illegal healers. "We have only 38 registered healers in Nyendo yet the division has 381 practicing. The situation is worse at the district level where out of the 24,000 traditional healers only 885 are registered," he said. “This is senseless cruelty. It must stop forthwith,” Jakaya Kikwete said on television, AFP news agency reports. “I am told that people kill albinos and chop their body parts, including fingers, believing they can get rich when mining or fishing,” he said. The order comes after the murder of 19 albinos in the last year. The BBC’s Vicky Ntetema in Dar es Salaam says there is a widespread belief in Tanzania that the condition is the result of a curse put on the family. Old women with red eyes have been killed in parts of Tanzania, after being accused of witchcraft, she says. In the past, Tanzania’s Albino Society has accused the government of turning a blind eye to the killing of albinos. There are some 270,000 albinos among Tanzania’s population of some 35 million, the highest population in East Africa. -50- Traditional African Clinic October 2008 ☻☻☻☻☻☻ Continued from page 49 - – Farmers reap Fortunes “We extract up to 98.6 per cent of Artemesinin from dried leaves of artemesia annua,” Mr. Robert Tumushabe, the factory supervisor of AAPl, said. The factory processes 12 tonnes of dried artemesia leaves per day. One tonne of dried Artemesia leaves produces six kilogrammes of crude artemesinin crystals. The Artemesin is then sold to the world’s renowned pharmaceutical companies such as Cipla Pharmaceutical of India from where Artemesinin-based drugs are manufactured. “Our market is worldwide but we sell most of our bulk in India,” Mr Freedie Zagyeda, the chief executive officer of AAPL, said. There is growing demand for Artemesinin as leading pharmaceuticals on manufacture of Artemesinin-based drugs after World Health Organisation authorized Artemesinin combination therapy as the new line of malaria treatment. Unfortunately, this demand has not translated into higher Artemesinin prices on the world market instead prices have been falling. World market prices fell from $350 per Kg in 2005 to $200 per Kg in 2007, a thing that has negatively impacted on the company’s bottom line. Although Mr Zagyenda maintains that the falling Artemesinin prices on the world market will not affect the company’s relationship with the farmers, testimonies show that the farmers are already feeling the pinch. Out-growers are complaining that their produce is rotting away in their stores as the company remains reluctant to collect. “I have sacks of dry leafs stuck here,” Mr Bitungukye said. “Much as I would like to keep growing artemesia, I cannot because of lack of market.” Mr Tabaro said: “Nowadays these people [AAPL] buy on credit. They are not treating us as they did previously.” He added: ‘I have stop planting because I cannot sell.” Growing Stock Mr Zagyenda said the company cannot abandon farmers and will stick to its promise of buying whatever stock the farmers have. “We provide free seedlings to farmers through our extension agents; it is a joint investment. That is assurance enough that we have interest in their stock,” Mr Zagyhenda said. According to him, the company slowed down on buying as a way to contain the growing stock. “We slowed down on buying as a way of storing the stock with the farmers. Currently we have more stock than the available warehouse space,” he said. “As soon as we dispose of the stock in our stores, we will begin buying.” He said buying on credit is part of the company’s new system of “streamlining field payment.” The company discarded the “on-spot payment system”, though popular with farmers, had its own shortfalls. “Farmers would bring to buying centres more or less produce than anticipated, which disorganised our accounting system” Mr Zagyenda said. “We later adopted an organized way of buying where we issue holder certificates to farmers for whatever we have bought.” Speculators He believes the current discontent among farmers is mainly fuelled by speculators who were caught off guard by the company’s change of heart. “They buy quantities in the hope of cashing in on the stock during the time of scarcity. They are now getting impatient,” he said. “Genuine farmers stay put because we will begin buying in two months time.” AAPL operates an out-grower scheme supported by the company’s nucleus farms. Farmers receive technical advice from the company’s extension who have basic training in the agronomy and management of Artemesia annua. “We train extension workers to assist farmers with the growing of Artemesia,” Mr Rugwiza said. It is these agents that also determine the quality of the leaf. The agents mainly operate in the five regions of Kabale District. Farmers receive free seedlings from extension agents. Farmers then plant the seedlings, which take about 3 to 4 months to mature before harvest. The leaves are dried for 2 to 3 days and later sold at collection centres before it is transported to the factory for processing. A kilogramme of dried artemesia annua leaves cost Shs1,000 per kg. The plant is best suited to the alpine climate present in Kabale. And as such, the plant has not encountered diseases, which makes it easier for farmers. Trials are also going on in the surrounding district of Mbabara and Ntunogamo. “There are dry leaves waiting to be collected in Mbarara,” Mr Rugwiza said. As the world prices of Artemesinin continue to tumble, the company is planning to diversify its product range. “We conducting trials for new crops,” Mr Zagyenda said. The company has hired services of an Indian Agronomist, Dr S.K. Natarajan to carry out the trials. -51- Traditional African Clinic October 2008 ☻☻☻☻☻☻ ‘Malnutrition Increases Resistance to ARVs’ A quarter of people on ARVs are malnourished. These deter the drugs from acting as required. Jane Nafula Daily Monitor July 21. 2008 “When you are infected, you have to increase on the food intake. An additional mug of nutritious porridge, Katogo [beans with cassava or matooke (banana) or groundnuts or greens], and other snacks must be taken between meals so that the body gets the required amount of energy to fight the virus,” Dr Mwadime said. “When the virus is in its advanced stage, at least two mugs of nutritious porridge are recommended.” ☻☻☻☻☻☻ Severe malnutrition among people living with HIV/Aids is one of the factors forcing the HIV virus to become resistant to antiretroviral drugs. The Regional Nutrition and HIV/Aids Advisor for the Food and Nutrition Technical Assistance (FANTA) Project, Dr Robert Mwadime, said malnourished patients have thin muscles and weak bodies that deter the drugs from acting as required. “Patients who are thin lack the muscles and nutrients needed to support the process of absorbing, metabolizing and distributing the drugs in the body,” Dr Mwadime said. Dr Mwadime told a workshop on nutrition and HIV monitoring and evaluation at Entebbe last week. He said even a deficiency of one specific nutrient can affect this process. Participants were drawn from Kenya, Tanzania, Rwanda, Zambia, Namibia, Malawi and Ethiopia. Dr Mwadime said malnutrition may lead to excessive interaction of the drugs with the nutrients and affect its effectiveness. He said the HIV virus can also become resistant if a patient does not take the drugs as prescribed. The resistance of HIV to ARVs is one of the major challenges facing the government’s programme of prolonging the lives of its patients. Dr Mwadime said the number of malnourished people living with HIV/Aids is increasing. “It is estimated that one of every four people starting to take ARVs, is malnourished,” he said. About 30,000 of 170,000 people who are on antiretroviral therapy are likely to be malnourished. Dr Mwadime also said that between 30 and 40 per cent of malnourished children who are admitted at Mwanamujimu clinics have HIV/Aids. Mwanamujimu are nutrition centres where malnourished children are put on special diet to regain lost body nutrients. He said the World Health Organisation requires people who are HIV positive to eat more food than they were eating before they became infected. 9 Million Ugandans Starving – Museveni 213,000 Million People Starving in Sub-Saharan Africa. Food is exported to neighbouring countries. John Augustine Emojong Daily Monitor October 20, 2008 President Yoweri Museveni has revealed that close to nine million Ugandans are starving due to food shortage caused by the effects of climate changes. In a speech read for him by the Third Deputy Prime Minister and Minister for Information and National Guidance, Mr Kirunda Kivejinja during celebrations to mark the World Food Day in Tororo on Thursday, Mr. Museveni said at least 213 million people in Sub-Saharan Africa are starving due on food shortage. He said the climate change, which is affecting food production, is a big threat to Uganda’s economy. He said the government is improving the meteorological department to enhance climate change forecasts that would give farmers better guidance. “We need to strengthen our meteorological departments so as to be able to give our farmers accurate information on climate change. We have been relying on guesswork most of the time,” Mr Museveni said. Mr Museveni said the government has increased funding to the National Agricultural Advisory Services programmes to help farmers diversify food production. World Food Programme (WFP) representative Hakan Tongul revealed that 700,000 people are facing starvation in Karamoja sub-region. Mr Tongul blamed the ever increasing food prices across the world on bio-energy production which has been on the rise in the past few years. He, however, noted that though Uganda is not very much affect by the effects of bio-energy production, much of the food produced is exported to neighbouring -52- Traditional African Clinic October 2008 Continued on page 53 Continued from page 53 – 9 M Ugandans Starving countries. “It is the neighbouring countries such as Kenya and Sudan that are causing food shortages for Uganda because much of the food produced is taken there,” Mr Tongul said. He said the WP was now changing its strategy from food aid to food existence by supporting food production programmes rather than keep buying and donating it, except in special circumstances. He revealed that last year, the WP spent $55 million to purchase food in Uganda, adding that WP expects to spend close to $100 million next year if the situation continues to worsen. ☻☻☻☻☻☻ Uganda’s Population Growth at 1.2 M Annually Evelyn Lirri Daily Monitor June 27, 2008 A fertility rate of 6.7 per cent among Ugandan women is contributing to the country’s high population which experts say is now growing by 1.2 million people annually. This surge in population growth, which is reportedly among the highest worldwide threatens to put enormous pressure on the government’s ability to provide social services like health, education and housing. “Every year the population of Uganda increases by over 1.2 million people, and at this rate, the country will have 130 million people by 2050,” the Population Secretariat said in a statement to announce this years’ Population Day set for July 11. Uganda will celebrate the day in Mbarara District under the theme “Promote and Invest in family Planning for National Development’. The day focuses on the right to access to family planning information and services to help people make informed choices about reproductive health issues. “This theme is timely because Uganda’s population is growing at a high rate and there are few measures in place to check this, “the statement reads in part. “Uganda’s population grew from 4.8 million people in 1950 to 24.3 million in 2002. It is estimate to be about 30 million today.” It says that a high population will undermine the country’s efforts to achieve socialeconomic transformation and development.” The Population Secretariat which falls under the Ministry of Finance, Planning and Economic Development, observes that the high population has a bearing on the current rising food prices and food shortages both in Uganda and globally. Although the availability and use of effective contraception is a key to slowing population growth, only 24 percent of married women in Uganda reportedly use contraceptives. ☻☻☻☻☻☻ Briefly - Condom Shortage by October – MP Daily Monitor June 27, 2008 Uganda is likely to face a shortage of reproductive health commodities by October this Network for African Women Ministers and Parliamentarians members said. “We are likely to have a severe shortage of condoms by October, Mityana MP Sylivia Namabidde said. “It will be very severe if the Ministry of Health does not prioritise these commodities.” Members of NAWMP said the budget had not addressed the issue of reproductive health yet the country is among those committed to attaining Millennium Development goals and especially the fifth MDG. The fifth MDG aims at reducing of maternal deaths to three quarters by the year 2015. However, the members said the country was unlikely to achieve this since the budget never mentioned anything about maternal health. ☻☻☻☻☻☻ Only 38% Ugandans Know Their HIV Status Daily Monitor April 19, 2008 The Minister of Health, Steven Mallinga has said 38 per cent Ugandans know their HIV status and said this number is still low if HIV/Aids is to be controlled and prevented from spreading further. Dr Mallinga disclosed this on Thursday while launching the Routine HIV Counseling and Testing at Hoima Regional Referral Hospital. The Minister called upon the entire population to go for free HIV/Aids counseling and testing. -53- Traditional African Clinic October 2008 ☻☻☻☻☻☻ Mission Statement Our aim at The African Traditional Herbal Research Clinic is to propagate and promote the awareness in Afrikan peoples at home and abroad of their health, biodiversity, history and cultural richness. We gather pertinent information on these issues and disseminate these freely to our people in Uganda, the rest of the continent, and anywhere in the Diaspora where Afrikans are located…. One of the main ingredients for increasing poverty, sickness, exploitation and domination is ignorance of one's self, and the environment in which we live. Knowledge is power and the forces that control our lives don't want to lose control, so they won't stop at anything to keep certain knowledge from the people. Therefore, we are expecting a fight and opposition to our mission. However, we will endeavor to carry forward this work in grace and perfect ways. “Where there is no God, there is no culture. Where there is no culture, there is no indigenous knowledge. Where there is no indigenous knowledge, there is no history. Where there is no history, there is no science or technology. The existing nature is made by our past. Let us protect and conserve our indigenous knowledge.” ☻☻☻☻☻☻ CALENDAR OF EVENTS SPECIAL EVENT: PLACE: AFRIKAN TRADITIONAL HERBAL RESEARCH CLINIC TIME: Herb of the Month KATAZAMITI (Bridelia micrantha) Despite intensive efforts to control malaria and HIV/AIDS, these diseases continue to be the greatest health problems facing Africa. It is estimated that there are at least 300 million clinical cases (worldwide) of malaria per annum, making it and HIV/AIDS (33-36 million worldwide) two of the top three killers among diseases in Africa. Katazamiti, native to sub-Saharan Africa is a semideciduous to deciduous tree up to 20 m tall with a dense rounded crown and tall, bare stem. All parts of the plant are used in traditional medicine. Bridelia micrantha, as it is formerly called, is traditionally used in the treatment of stomach ailments and diseases such as gastritis, salmonellosis, gastro-enteritis, diarrhea and constipation, tapeworms and as an emetic for poisons (causes vomiting). Scientific studies have shown that extracts of the whole stem demonstrate antimicrobial activity by inhibiting the growth of Helicobacter pylori (H. pylori) and campylobacter jejuni/coli. It is used as a treatment for skin problems such as ulcers, boils and rashes; for respiratory problems such as persistent cough, TB, pneumonia, bronchitis and pleurisy; as an analgesic (pain reliever); as an antimalarial; for toothache and gum diseases; for painful menstruation; to prevent abortion; as a stimulate and restorative tonic (alternative) for fortifying pregnant women; for sickle cell anemia, HIV/AIDS; and anemia in general. Preliminary research on medical properties of Katazamiti has shown this herb to be beneficial in treating HIV/AIDS as it cures diarrhea and stomach discomfort and has anti-cancer properties, which are common illnesses in AIDS and contributes to the well-being of the patient. It has also been shown to be a possible principle inhibitor to HIV1 reverse transcriptase. Katazamiti is also traditionally used in treating psychological problems such as neurosis and psychosis and for protection against one’s enemies. ☻☻☻☻☻☻ Afrikan Traditional Herbal Research Clinic 1175A Mukalazi Road, P.O. Box 29974 Bukoto, Kampala, Uganda East Africa Phone: +256 (0) 782 917 902 Email: clinic@blackherbals.com ADDRESS CORRECTION REQUESTED BULK RATE US POSTAGE PAID PERMIT 00000 Mailing Address Street Number and Name City, Country, etc. -54- Traditional African Clinic October 2008 NO.