CAPSULE-BASED INHALERS: UNDERSTANDING CAPSULE-BASED INHALERS:

CAPSULE-BASED INHALERS:
UNDERSTANDING THE SCIENCE
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25 November 2014, Conf. No N11-8614
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Dates
25 November 2014 Start: 09.30 – Finish: 15.45
Registration & Coffee
25 November 2014 09.00
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Hotel Ramada Plaza
Messeplatz 12
Basel
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Switzerland
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Conference No. N11-8614
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JOIN US ON
CAPSULE-BASED
INHALERS:
UNDERSTANDING
THE SCIENCE
Benefits from attending:
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Better understanding of which device, capsule or
formulation to use for dry powder inhalation
Understand the key parameters in powder aerolisation
from Dry Powder Inhalers (DPI)
Understand capsule properties and puncturing by DPIs
Assess the effect of lubricant levels on the internal
surfaces of inhalation capsules
Utilise the design of experiments to optimise internal
lubricant content of inhalation capsules
Network with senior inhalation professionals
Chairman:
Dr Michel Deleers, Managing Director of Deelers-Projects
S.p.r.l and Master of Teaching at Faculty of Pharmacy Universite Libre
De Brussels, Belgium
With a panel of inhalation experts from academia and industry
Register for your free place online at
www.management-forum.co.uk
or by phone on +44 (0)1483 730071, fax 730008
25 November 2014
Hotel Ramada Plaza, Basel, Switzerland
INTRODUCTION
FACULTY OF SPEAKERS: (Cont.)
This one day seminar has been designed to
enable delegates to understand the science
behind capsule-based inhalers. The programme
will provide a comprehensive overview of
capsule-based inhalers for dry powder inhalation.
It will consider various aspects of inhalation
capsules and powders and provide a state of the
art review of the technology available. This event
will be an excellent opportunity to discuss the use
of capsule-based inhalers and provide an informal
environment to network with fellow inhalation
professionals from industry and academia.
Dr Imran Saleem is a Senior Lecturer in
Pharmaceutical Technology within the School of
Pharmacy & Biomolecular Sciences, Liverpool
John Moores University, UK, since 2008. He
obtained his Pharmacy degree from the same
university and is a registered pharmacist. In 2003,
he received his Doctor of Philosphy (Ph.D) in drug
delivery from Aston University, UK. Upon
completing his Ph.D he went on to undertake a
Postdoctoral Research Fellow at University of New
Mexico in the Advanced Drug Delivery Laboratory
of Dr H Smyth, working in the area of dry powder
inhalation. He has been working in and has
published numerous papers in the area of
pulmonary drug delivery since 2006. His research
is aimed at developing novel delivery systems for
targeting therapeutic agents to their site of action,
with particular emphasis on lung diseases via dry
powder pulmonary delivery.
Brian Jones is Scientific Advisor for Qualicaps
Europe, S.A.U. and is an Honorary Senior Lecturer
in the School of Pharmacy & Pharmaceutical
Sciences, Cardiff University, Cardiff, UK. He
graduated from the University of Wales with a
BPharm. in 1961 and an MPharm. in 1973. He
is a Fellow of the Royal Pharmaceutical Society
of Great Britain. The major part of his career (29
years) was spent working for Eli Lilly & Co. Ltd,
UK where he was involved in providing
technical support to their capsule manufacturing
and filling operations and in providing a service
to their capsule customers in Europe, Asia, Africa
and North America and took early retirement in
1994. In Lilly he was involved in the development
of the first inhalation capsule in the late 1960s,
used in the Spinhaler® of Fisons, UK. His research
interests are in the properties of inhalation grade
hypromellose capsules and their use in dry powder
inhalers.
Dr Nour Kayali is a senior mass spectrometrist
in the Mass Spectrometry Center of Complutense
University of Madrid. He is involved in
developing methods in GCMS and LCMS to
identify and quantify individual organic molecules
in a biological or non-biological extracts. His
research interest is related to trace analysis
focusing on instrumental developments in solid
phase microextraction, SPME.
Fernando Diez is Business Development Manager
for Qualicaps Europe. He has an MBA and
degrees in Chemistry and Physics. His work
mission is creating new business opportunities
outside of the formal review/tender process. Prior
to Qualicaps he worked for several companies
including Sanofi, Dow Chemical and Sniace. He
has published several papers and posters on
capsule technology.
WHO SHOULD ATTEND
This seminar will be of interest to; Directors, Business
Development Managers, Senior Executives in
Technical Departments, Product Development
Managers, Project Managers, Research &
Development professionals & Heads of Medical
Device Departments in the inhalation market.
CHAIRMAN:
Michel Deleers, Managing Director of
Deleers-Projects s.p.r.l., Master of Teaching at
Faculty of Pharmacy and Industrial Collaborator
at Beams, Polytechnic School, University of Libre
de Brussels (ULB), and Co-founder of Talent Cy.
He has authored around 100 publications and
registered 22 Patents in Pharmaceutical
formulations. Past positions include: CEO of
Oncobel s.a.,Vice President New
Pharmaceutical Technologies in R&D UCB
Pharma, and Vice President Global
Pharmaceutical Technology & Analytical
Developments, Clinical Supplies (UCB Pharma
s.a.).
FACULTY OF SPEAKERS:
Dr Nathalie Wauthoz, holds a post-doctoral
position in the Laboratory of Pharmaceutics and
Biopharmaceutics, Faculty of Pharmacy, University
of Libre de Brussels (ULB), she previously held a
post-doctoral position in “Unité Micro et
Nanomédecines Biomimétiques (Mint)”, INSERM
UMR-S 1066 in Angers (France) - Euronanomed
project “Lymphotarg”, and was a Research/
Assistant in Pharmaceutical Technology in the
Laboratory of Pharmaceutics and
Biopharmaceutics, Faculty of Pharmacy, ULB. Her
current research interests include Pulmonary Drug
Delivery System: Development of Powders for
Inhalation (DPIs); anti-cancer, antifungal and
anti-asthmatic drugs; In Vitro and In Vivo
Evaluation: cell culture and models of lung
tumours and invasive pulmonary aspergillosis.
PROGRAMME
09.30 u Registration and Coffee
10.00 u Welcome and Introduction from Qualicaps
Ciro Ahumada, President EMEA, Qualicaps Europe, S.A.U., Spain
10.10 u Chairman’s Introduction
Michel Deleers, University Libre de Brussels, Belgium
10.15 u Dry Powder for Inhalation: Which Device,
Capsule and Formulation?
Dr Nathalie Wauthoz, University Libre de Brussels,
Belgium
11.00 u Key Parameters in DPI Aerosolization
Dr Imran Saleem, Liverpool John Moores University, UK
11.45 u Capsules Properties and Puncturing by DPIs
Brian Jones, Cardiff University, UK
12.30 u Networking Lunch
13.30 u Effect of Lubricant Level on the Internal
Surface of HPMC Capsules Using HS-SPME GC-MS and AFM
Dr Nour Kayali, Universidad Complutense de Madrid, Spain
14.15 u Using Design of Experiments (DOE) to Optimise
Internal Lubricant Content in Inhalation Capsules
Fernando Diez, Qualicaps Europe, S.A.U., Spain
15.00 u Panel Discussion 15.30 u Chairman’s Concluding Remarks
Michel Deleers, University Libre de Brussels, Belgium
15.45 u End of Seminar and Tea
DOCUMENTATION
Delegates will receive a course material folder containing comprehensive documentation provided by the
speakers, which will be a valuable source of reference for the future.
Register for your free place online at: www.management-forum.co.uk