1 Meeting of the Core Facility st

1st Meeting of the Core Facility
We are honoured that this meeting is included in the
events to celebrate the 50th anniversary of the
foundation of the Medical Faculty Mannheim.
About the Core Facility
The core facility LIMA was founded in 2011 with the
goal of giving researchers and clinicians access to a
powerful and innovative bio-imaging tool for the
study of biological processes in action. The core
facility LIMA provides dynamic imaging equipment
i.e. state of the art laser scanning microscopes along
with technical expertise and is currently collaborating
on studies that include angiogenesis, tumour
metastasis, cardiovascular physiology, cellular
signalling, nociception of acute and chronic pain as
well as neuronal polarity.
Venue
The meeting will be held at the auditorium of the
Medical Faculty Mannheim, Hörsaal H02, Alte
Brauerei, Röntgenstr. 7, 68169 Mannheim on the 7th
of November 2014, starting at 9 o’clock with the
welcoming address of the Dean.
7. November 2014
The campus is easily accessible by public transport.
Fiftieth Anniversary of the Med
Mannheim Meeting
1st Mannheimthe Core F
of the Core Facility of
LIMA
“LIMA – Live Cell Imag
at the CB
Entrance to the venue is through the courtyard.
1st
Contact
LIMA: J. Bucher and W. Greffrath, CBTM, LudolfKrehl-Strasse 13-17, Tridomus C
In celebration of the 50th
Anniversary
Medical
Faculty Mannheim, Uni
th
of the foundation of theNovember 7 2014, 9
Lecture Room 02, „Alte Braue
Medical Faculty Mannheim
Meeting secretary: R. Läufer
nphys.sekretariat@medma.uni-heidelberg.de 9.00 – 9.15
Organisation: J. Bucher, W. Greffrath and R. Läufer
Text and Layout: S. Gorbey
“Welcome address” by the Dean of
University of Heidelberg, Prof. Dr. r
Introduction by the Director of the C
Neurobiology
Bio-imaging tools hold enormous potential for a wide
variety of diagnostics and therapeutic applications
and the core facility is very proud to have established
a fruitful interaction with clinicians of the Medical
Faculty. Since 2014 the core facility is a member of the DGF
research infrastructure portal “RIsources”, which
gives researchers in Germany the possibility to use
the service.
Stem cells by Karen Bieback
The mission of the core facility is to train and teach
researchers and clinicians interested in studying
biological processes in living cells or organisms. In
addition the core facility also develops and refines
new methods and applications, which are made
available to the members of the CBTM and
researchers of the Medical Faculty Mannheim.
9.15 – 9.30
Julia Bucher, CBTM, Core Facility L
The Core Facility „LIMA - Live Ce
Who we are and what we do
9.30 – 10.00
Hans-Ulrich Dodt, Technical Univer
Ultramicroscopy of cleared mous
10.00 – 10.15
Matthias Carl, CBTM, Boutros grou
Following axons in the asymmet
10.15 – 10.45
Reinhard Köster, Technical Univers
Probing cerebellar function with
10.45 – 11.15
Coffee Break (catering at the Old B
Vascular Biology I
11.15 – 11.45
Arndt Siekmann, Max-Planck-Institu
Illuminating blood vessel formati
11.45 – 12.00
Andreas Fischer, CBTM and DKFZ
Multiple PDZ domain protein con
12.00 – 12.30
Hellmut Augustin, CBTM and DKFZ
Imaging technology to observe
the natural course of biology in
action, within living organisms.
Program
9.00 – 9.15 “Welcoming address” by the Dean of the
Medical Faculty Mannheim, University of Heidelberg,
Prof. Dr. rer. nat. Dr. med. Dr. h. c. Uwe Bicker
and introduction by the Director of the CBTM,
Prof. Dr. med. Rolf-Detlef Treede
Neurobiology 14.00 – 14.30 Two-and three-dimensional real time
live confocal imaging of microvascular networks in
situ: topology, morphology Ca2+ signaling and tone. Theodor Burdyga, University of Liverpool, Great Britain
14.30 – 14.45 BK channels transform phasic into
tonic smooth muscle. Rudolf Schubert, CBTM
Cellular Biology
Chair: WOLFGANG GREFFRATH Chair: MICHAEL BOUTROS
9.15 – 9.30 The Core Facility „LIMA - Live Cell Imaging
Mannheim“ : Who we are and what we do.
14.45 – 15.15 Systems Microscopy - using high
throughput microscopy to study cellular protein
dynamics for systems biology applications. Julia Bucher, CBTM, Core Facility LIMA and Treede group
Drosophila oogenesis by Veit Riechmann
Vascular Biology II
Chair: CHRISTIAN SCHULTZ
Morning Session
9.30 – 10.00 Ultramicroscopy of cleared mouse brains
and mouse embryos. Hans-Ulrich Dodt, Technical University of Vienna, Austria
Rainer Pepperkok, EMBL, Heidelberg
15.15 – 15.30 Control of epithelial
morphogenesis via regulated endocytosis. 10.00 – 10.15 Following axons in the asymmetric brain.
Matthias Carl, CBTM, Boutros group Veit Riechmann, CBTM, Boutros group
10.15 – 10.45 Probing cerebellar function with light.
15.30 – 16.00 Coffee Break
Reinhard Köster, Technical University of Braunschweig
10.45 – 11.15 Coffee Break
Vascular Biology I
Chair: JENS KROLL
Rat skin: TrpV1: red, PGP: green, Collagen: SHG by Julia Bucher
Afternoon Session
11.15 – 11.45 Illuminating blood vessel formation in the
zebrafish. Arndt Siekmann, Max-Planck-Institute for Molecular Biomedicine,
Münster
11.45 – 12.00 Multiple PDZ domain protein controls
vascular permeability. Andreas Fischer, CBTM and DKFZ, Heidelberg, Augustin group
12.00 – 12.30 Vascular control of health and
disease: Seeing is believing. Hellmut Augustin, CBTM
and DKFZ Heidelberg, SFB/Transregio 23
12.30 – 14.00 Lunch Break
Catering at the Old Brewery
16.00 – 16.15 Cord blood-derived endothelial
progenitor cells emerge from a hematopoietic CD45+
population: Multi-photon imaging to complement flow
cytometric data.
Karen Bieback, CBTM, Klüter group
Technical perspectives
Chair: JONATHAN SLEEMAN
16.15 – 16.30 The role of ASAP1 in tumor metastasis.
Supriya Saraswati, CBTM, Sleeman group
16.30 – 17.00 Fluorescence Microscopy at the
Nanoscale.
Christoph Cremer, Institute for Molecular Biology gGmbH, Mainz
17.00 – 17.15 High-resolution microscopy of the axon
initial segment and cisternal organelle in retinal
ganglion cells.
Maren Engelhardt, CBTM, Schultz group
17.15 – 17.30 General discussion, summary
and ”fare-well“ by the Executive Leader of
the Core Facility LIMA, Wolfgang Greffrath