2014-2015 Research Discussions

RESEARCH DISCUSSIONS / 2014-15
BIOM/PHAR 295
DEPARTMENT OF PHARMACOLOGY
LEICHTAG 107, FRIDAYS
TIME SLOT A -- 9:00 - 9:30 AM TIME SLOT B -- 9:30 - 10:00 AM
(20 min. presentation, 10 min. question/answer period)
For other AV needs, contact the Pharmacology Education Office at least one week prior to your presentation
Refreshments served at 8:45 AM
ABSOLUTELY NO CHANGES WITHOUT PHARMACOLOGY EDUCATION OFFICE APPROVAL
3-Oct
A Dorrestein
Vanessa Phelan
Characterizing the Chemotypic Landscape of Cystic Fibrosis Sputum
3-Oct
B Guan
Jenna Jewell
Differential Regulation of mTOR by Amino Acids
10-Oct
A Dixon
Vinnie Tagliarbracci
Phosphorylation of secreted proteins by a new family of kinases
10-Oct
B Evans
Nuno Camboa
HIF1α represses ATF4 and preempts p53 pathways to promote proliferation of fetal cardiomyocytes
17-Oct
A Insel
Anna Busija
Cardiac myocyte-specific overexpression of caveolin-3 enhances response to β-adrenergic stimulation
17-Oct
B Gustafsson
Babette Hammerling
Identification of a Novel Pathway of Parkin-Mediated Mitochondrial Clearance in Cardiac Myocytes
24-Oct
A Tsien
Varda Levram-Ellisman Very long-term memories may be stored in the pattern of holes in the perineuronal net
24-Oct
B Trejo
Buxin Chen
N-linked glycosylation of protease-activated receptor-1 regulates signal pathway bias
31-Oct
A Joiner
Jim Robinson
Regulation of the sleep/wake cycle in Drosophila by Adar and its effectors
31-Oct
B Karin
Amy Strasner
PPARg as a potential mediator of ADSC-derived mammary CAF
7-Nov
A Newton
Maya Kunkel
Paradoxical increase in Protein Kinase D phosphorylation upon inhibitor binding
7-Nov
B Guan
Toshiro Moroishi
A YAP/TAZ-Induced Feedback Mechanism Regulates Hippo Pathway Homeostasis
14-Nov
A Heller Brown
Stephanie Dusaban
PLCε mediates heterotrimeric and small GTPase signaling in CNS injury and disease
14-Nov
B McCammon
Yinglong Miao
Structure-based Design of Allosteric Modulators of a Muscarinic G-protein Coupled Receptor
21-Nov
A Tsien
Csilla Felsen
Exploiting Protease Activity to Image and Study Inflammatory States
21-Nov
B Yang
Laurent Fattet
Role of Twist1 in cellular mechanosensing
28-Nov
Thanksgiving Holiday
5-Dec
A Heller Brown
Charlie Gray
The role of CaMKIIdelta splice variants in ischemia/reperfusion injury
5-Dec
B Insel
Aaron Overland
GPCRs and Heterotrimeric G proteins directly regulate Membrane Type-1 Matrix Metalloprotease
12-Dec
A Joiner
Meilin Wu
Regulation of ion channels and ionotropic receptors by Ly6 proteins
12-Dec
B Guan
Henry Park
The Role of YAP/TAZ as Mediators of Alternative Wnt Signaling
19-Dec
A Tukey
Shujuan Chen
Nuclear receptor co-repressor NCoR1 and developmental expression of intestinal xenobiotic processing genes
19-Dec
B Adams
Malik Keshwani
Proline-Directed Phosphorylation regulates SR Protein Function and Splicing
12/26/2014 - 1/2/2015
Holidays
9-Jan
A S. Taylor
Hiruy Meharena
Synchronized Intra-Molecular Interactions Regulating EPK Function
9-Jan
B Trejo
Neil Grimsey
Differential regulation of GPCR endosomal sorting by Rab11A and Rab11B
16-Jan
A Karin
Juyoun Kim
New ways to combat NASH: Defining the role of TNFR1 in de novo lipid synthesis through caspase2-mediated SREBP1 processing
16-Jan
B Radic/P. Taylor Zoran Radic
Allosteric modulation of butyrylcholinesterase oxime reactivation, in vitro and in vivo
23-Jan
A Tsien
Stephen Adams
Multi-color electron microscopy
23-Jan
B Newton
Ksenya Cohen-Katsenelson PHLPP phosphatase as a modifier of histone code
30-Jan
A Heller Brown
Alessandra Castaldi
Role of GPCRs in Cardiac Progenitor Cells
30-Jan
B Karin
Tse Yuan (Jerry) Wong
Chronic NF-κB activation sensitizes intestinal epithelial cells to tumour necrosis factor-induced programmed cell death
6-Feb
A Dixon
Xing Guo
Phospho-regulation of the 26S proteasome
6-Feb
B P. Taylor
Kasia Kaczanowski
Novel nAChRs Modulators for Treating CNS Disorders: Discovery of AChBP Cooperative Ligands
13-Feb
A S. Taylor
Ronit Ilouz
Specificity and distinct spatial localization of PKA regulatory subunits in the brain
13-Feb
B Karin
Zhenyu Zhong
The role of p62 in innate immunity
20-Feb
A Tsien
Alex Kislukhin
Fluorinated materials for non-invasive cell tracking in vivo
20-Feb
B Newton
Corina Antal
Protein Kinase C Loss-of-Function Mutations in Cancer Reveal Role as Tumor Suppressor
27-Feb
A Karin
Debanjan Dhar
Signaling Pathways that Lead to Hepatocellular Carcinoma
27-Feb
B Dennis
Varnavas Mouchlis
Hydrogen/Deuterium Exchange Mass Spectrometry and Molecular Dynamics Reveal the Interactions of Membrane Phospholipids and Inhibitors with Phospholipases A2
6-Mar
A Insel
Shu Zhou
GPCRs as potential therapeutic targets in pancreatic cancer-associated fibroblasts
6-Mar
B Trejo
Michael Dores
GPCR signaling initiates ALIX ubiquitination to regulate GPCR lysosomal sorting
13-Mar
A Gustafsson
Amabel Orogo
Accumulation of mtDNA Mutations Impairs Mitochondrial Function in Cardiac Progenitor Cells and in the Heart
13-Mar
B Joiner
Rou-Jia Sung
Novel Modulation of Glutamate receptor activity by a family of prototoxin-like molecules
20-Mar
A S. Taylor
Ping Zhang
PKA macromolecular signaling complex
20-Mar
B Yang
Haeyun Jung
The plasticity of Twist1-mediated EMT regulates tumor dormancy
March 27 Cesar Chavez Holiday
3-Apr
A Hook
Bailey Miller
Marine natural products in the neurosciences: screening and isolation of cysteine cathepsin inhibitors
3-Apr
B Daneman
Roeben Munji
Neurochemical balance and the blood-brain barrier
10-Apr
A Karin
Koji Taniguchi
The Role of gp130 Signaling in Intestinal Homeostasis and Tumorigenesis
10-Apr
B McCammon
Steffen Lindert
Molecular Dynamics and Calcium Binding Studies on Cardiac and Skeletal Troponin
17-Apr
A Tsien
Mike Whitney
Targeted probes for monitoring disease and image guided surgery
17-Apr
B Daneman
Fabien Sohet
LSR, a tricellular tight junction protein involved in Blood-Brain Barrier formation
24-Apr
A Trejo
Patrick Menzies
Activated Protein C Promotes Co-Association of Protease-Activated Receptor 1 and Sphingosine-1-Phosphate Receptor 1 at the Plasma Membrane
24-Apr
B McCammon
Alisha Caliman
Allosteric Modulators of the Sphingosine-1-Phosphate Receptor Subtype 1
1-May
A Yang
Trenis Palmer
Novel mediators of invadopodia mediated degradation
1-May
B Reya
Jeevisha Bajaj
Adhesive signaling in leukemia growth and progression
8-May
A S. Taylor
Kris Haushalter
ROS-dependent modulation of PKA signaling in cardiac ischemia/reperfusion injury
8-May
B Joiner
Clare Puddifoot
Modulation of nicotinic acetylcholine receptors by endogenous prototoxins
15-May
A Handel
To be decided
Structure of the complex of chemokine receptor CXCR4 with the viral chemokine, vMIP-II
15-May
B Reya
Ray Fox
Inhibition of Musashi Disables Progression of Pancreatic Adenocarcinoma
22-May
A Chang
Steve Rees
Perpetual Toxicity: The Dysregulation of P-gp by Environmental Pollutants
22-May
B Jain
Jain
Metabolism and Metabolomics of Human Disease
29-May
A Heller Brown
Olivia Yu
The role of GPCRs in transcriptional coactivator responses
29-May
B Chun
Nicole Stoddard
The role of lysophosphatidic acid signaling in initiating premature infantile post-hemorrhagic hydrocephalus
29-May
C Leffert
Leffert
Liver stem cells and growth control
5-Jun
A Heller Brown
Andrew Willeford
Defining the Activity and Role of CaMKIId During B-Adrenergic Stimulation
5-Jun
B Lipton
Olga Prikhodko
S-Nitrosylation of CRTC1 Regulates CREB Activity in Neurodegenerative Disorders
5-Jun
C Gustafsson
Sarah Shires
Role of the E3 Ubiquitin Ligase Parkin in protein and organelle quality control
12-Jun
A Yang
Hannah Majeski
The role of Tyk2 in regulating Twist1 in response to matrix stiffness
12-Jun
B Joiner
Lawrence K. Satterfield
Investigation of the molecular mechanisms and neural circuitry underlying sleep homeostasis using Drosophila melanogaster as a model system
12-Jun
C Newton
Agnes Grzechnik
The Role of PHLPP in the Regulation of the Histone Code