postgraduate course clinical epidemiology

POSTGRADUATE COURSE
CLINICAL EPIDEMIOLOGY
26th-30th January, 2015
Faculty of Medicine, University of Belgrade
Belgrade, Serbia
FIRST ANNOUNCEMENT
Dear participants,
It is our great pleasure to announce that the Erasmus Medical Center, Rotterdam and Faculty
of Medicine University of Belgrade, within the ERAWEB II project, will organize one week
Postgraduate course Clinical Epidemiology, that will take place at the Head Building of the
Faculty of Medicine, University of Belgrade from January 26 to January 30, 2015.
Course is dedicated to clinical epidemiologists and clinical researchers, as well as
postgraduate students from the ERAWEB partner universities.
Looking forward to welcome you in Belgrade,
Prof. Nebojša M. Lalić
Dean, Faculty of Medicine,
University of Belgrade
Prof. Albert Hofman
Project Coordinator
Scientific Committee
Prof. Albert Hofman, Erasmus Medical Center, Rotterdam
Prof. Nebojša Lalić, Dean, Faculty of Medicine, University of Belgrade
Prof. Henning Tiemeier, Erasmus Medical Center, Rotterdam
Local Organizing Committee
Prof. Nebojša Lalić, Dean, Faculty of Medicine, University of Belgrade, President
Jelena Šantrić, PhD, Faculty of Medicine, University of Belgrade
Nataša Ognjanović, MSc, Faculty of Medicine, University of Belgrade
Ivana Katić, MSc, Faculty of Medicine, University of Belgrade
SCIENTIFIC PROGRAM
Lecturers:
Prof. Albert Hofman
Prof. Henning Tiemeier
Erasmus Medical Center, Rotterdam, the Netherlands
Monday, January 26, 2015
RISK
Lecture 1
Introduction, determinants of disease, disease risk, risk
from life table
Exercise 1
Incidence and risk
Lecture 2
Risk function
Background
Rose G. Sick individuals and sick populations.
Int J Epidemiol 1985;14:32-8.
Rothman KJ, Greenland S, Lash TL. Measures of occurrence.
In: Modern Epidemiology, Edition 3, chapter 3, Lippincott,
2008:32-50.
PROGNOSIS
Lecture 1
Prognosis, life table, censoring
Exercise
Population risk
Lecture 2
Introduction randomised clinical trial
Design
Study design 1
1. NSAIDs and Alzheimer’s disease
2. LpPLA2 and coronary heart disease
3. Vaccination for the prevention of HIV infection
4. Homocysteine and fractures
Background
Tugwell PX. How to read clinical journals III. To learn the
clinical course and prognosis of disease.
Can Med Ass J 1981;124:869-72.
Kurtzke JF. On estimating survival; a tale of two censors.
J Clin Epidemiol 1989;169-75.
Tuesday, January 27, 2015
THERAPY: EFFICACY
Lecture 1
Design options randomised trial
Design
Study design 2
Lecture 2
Analysis randomised trial
Background
Peto R, Pike MC, Armitage P, Breslow E, Cox DR,
Howard SV, Mantel N, McPherson K, Peto J, Smith PG. Design
and analysis of randomised clinical trials requiring prolonged
observation of each patient (part I and II).
Br J Cancer 1976;34:585-612, and Br J Cancer 197;7:1-39.
Cornfield J. Recent methodological contributions to clinical
trials. Am J Epid 1976;104:408-20.
Wedneday, January 28, 2015
THERAPY: SIDE EFFECTS
Lecture 1
Intended and unintended effects, confounding by indication,
meta-analysis
Design
Study design 3
Lecture 2
Meta-analysis
Exercise
Anticoagulation after myocardial infarction
Background
Miettinen OS. The need for randomisation in the study of
intended effects.
Stat Med 1983;2:267-71.
Miettinen OS, Caro JJ. Principles of non-experimental
assessment of excess risk, with special reference to adverse
drug reactions.
J Clin Epid 1989;42:325-31.
Egger M, Davey Smith G, Schneider M, Minder C. Bias in
meta-analysis detected by a simple graphical test.
BMJ 1997;315:629-34.
Lau J, Antman EM, Jimenez-Siwa J, Kupelnick B, Mosteller M,
Chalmers TC. Cumulative meta-analysis of therapeutic trials for
myocardial infarction.
N Engl J Med 1992;327:248-54.
Thursday, January 29, 2015
DIAGNOSIS
Lecture
Diagnostic tests, sensitivity, specificity, predictive value,
Bayes’ theorem.
Exercise
Bates DW, Cook F, Goldman L, Lee Th. Predicting bacteremia
in hospitalised patients – a prospectively validated study.
Ann Int Med 1990;113:495-500.
Background
Sox HC. Probability theory in the use of diagnostic tests.
Ann Intern Med 1986;104:60-6.
Friday, January 30, 2015
META-ANALYSIS
PRESENTATION OF STUDY DESIGNS
Evaluation
Closure
REGISTRATION
You can register on the following e-mails:
ivana.katic@mfub.bg.ac.rs
The Deadline for registration is January 16, 2015.
natasa_cms@med.bg.ac.rs
and
TRAVEL AND ACCOMMODATION
It is possible to use the organisational budget of the ERAWEB partner university to cover
travel and accomodation costs for coordinating staff or other members of the partner
universities. This is the responsibility of the partner universities. There is no additional
budget available.
For current ERAWEB students who would like to participate in the course, it is possible to
use the participation fee that the host university receives for the student. This is the
responsibility of the host university.
Belgrade is easily accessed by plain (direct flights from major European cities), as well as by
other means of transportation.
The entrance visa is not needed for EU countries and for a significant number of other
countries (please verify at the Embassy of Serbia).
Hotel accommodation offers wide variety of possibilities at different prices. Most of the
hotels are easily reachable from the airport (15-20 minutes by car).
The following hotels are at the vicinity of Course venue:
(5) Crystal Hotel www.crystalhotel-belgrade.rs
(6) Park Hotel www.hotelparkbeograd.rs
CONTACT:
Center for International Collaboration
Faculty of Medicine, University of Belgrade
Dr Subotica 8, 11000 Belgrade, Serbia
Phone/Fax: +381 11 3636327, +381 11 3636396
Natasa Ognjanovic
E-mail: natasa_cms@med.bg.ac.rs
Ivana Katic
E-mail: ivana.katic@mfub.bg.ac.rs