Forskningsberetning for Gentofte Hospital 2014

Transcription

Forskningsberetning
for Gentofte Hospital
2014
INDHOLD
Forord
2
Forskningsråd Gentofte
3
Forskningsenheden
4
Forskerkarriereprogram på Gentofte Hospital
5
Forskningspuljer 2014
6
Forskningens Døgn 25. april 2014
7
Forskningens Dag 26. november 2014
8
Forskningstemaer, -personale og publikationer 2014
9
Anæstesi afd.
10
Ernæringsenheden i Serviceafdelingen
11
Forskningsenheden i HR & Kvalitet
12
Hjertemedicinsk afd.
13
Hud- og Allergiafd.
20
Klinisk Biokemisk afd.
26
Lungemedicinsk afd.
28
Medicinsk afd. C
30
Medicinsk afd. F
33
Ortopædkirurgisk afd.
37
Røntgen- og skannings afd.
39
1
Forord
Pure rapport trukket juli 2015
Forskningsberetning 2014 for Gentofte
Hospital kan atter dokumentere en stor og
stigende forskningsaktivitet med en fremgang fra
2013 på knapt 12 % i antallet af publikationer,
og kurven har været flot stigende fra 2010-2014
(stigning i alt på ca. 40 %, PURE udtræk juni
2015).
Som det fremgår af denne beretning, har næsten
alle afdelinger haft fremgang eller bibeholdt et
meget højt niveau i perioden 2013-2014.
Den regionale evaluering af kvaliteten af hospitalets forskning (målt på pointgivende forskningsaktiviteter som journal impact factors, fondsbevillinger, ph.d.-grader mm.) har ligeledes ligget
meget tilfredsstillende i de foregående år. Den
regionale forskningsevaluering for 2014
foreligger i efteråret 2015
I 2014 er Hospitalsdirektionens og Forskningsenhedens program for den strategiske forskningsporteføljeledelse fortsat. Indsatsområderne i Gentofte Hospitals Forskningsstrategi 2013-2018 blev fulgt op ved
besøg på alle afdelinger i 2014, og handleplaner og anbefalinger for det videre arbejde med at lede og
udvikle forskningsorganisationerne er fulgt op og udbygget.
Der er fortsat stærk udvikling, aktivitet og international klasse i Gentofte Hospitals 3 Global Excellencemiljøer (Hjertemedicin, Hud- og Allergi samt Center for Diabetesforskning) og en særdeles lovende
udvikling i en række andre forskergrupper.
I 2011 bevilgede Gentofte Hospitals direktion 5 mio. kr. pr. år til oprettelse af et program for
flerårige halvtids-forskerdelestillinger rettet mod fastansatte læger og MVU’ere på postdoc og seniorforskerniveau. Denne ordning har haft stor succes målt på det overvældende antal af meget højt kvalificerede ansøgere og på det øgede videnskabelige output, der efterhånden tegner sig hos forskerne i disse
delestillinger. Forskerne har deltaget i udviklingssamtaler i årene 2013-2015, hvilket har givet mulighed
for strategisk forskningsunderstøttende coaching og karrierevejledning i henhold til forskerens og hospitalets muligheder, visioner og forskningsstrategi. Samtalerne har blotlagt entusiasmen og de meget
høje ambitionsniveauer hos forskerne. Delestillingsprogrammet understøtter således på unik vis hospitalets forskerkarriéreprogram med fremragende forskere og forskningsmiljøer i pipelinen.
På baggrund af det store antal af højt kvalificerede forskere, der ikke har opnået delestilling og på baggrund af afdelingernes og forskernes input fra site visits, ved vi, at der er et yderligere stort behov for
skemalagt forskningstid. Hospitalsdirektionen og Forskningsenheden har derfor taget initiativ til oprettelse af et antal delestillinger (20 % forskning) for læger i hoveduddannelse med et forskningsprojekt
tilknyttet Gentofte Hospital. I 2014 kørte et pilotforløb på denne stillingstype, og med disse erfaringer i
bagagen planlægges en ny stilling opslået i 2015.
Udviklingen i hospitalets forskningsmiljøer peger således fortsat positivt fremad, hvilket også dokumenteres på hospitalets Forskningens Dag, Videnskabeligt Symposium for delestillinger og ved Forskningens
Døgn i 2014 (se nedenfor).
Det er kendetegnende for forskningsmiljøerne på Gentofte Hospital, at der er en klar bevidsthed omkring snitflader til andre forskergrupper i det nu fusionerede Herlev og Gentofte Hospital, og der er en
skærpet opmærksomhed på identiteten som aktiv forsker i denne virksomhed, der er Region Hovedstadens næststørste forskningshospital.
På vegne af Forskningsenheden i Kvalitet og Udvikling
Jüri J. Rumessen
Forskningschef, dr.med.
2
Gentofte Matrikel
Herlev og Gentofte Hospital
August 2015
Forskningsråd Gentofte
Forskningsråd Gentofte består af forskningsansvarlige repræsentanter fra hospitalets afdelinger
og skal rådgive Direktionen i forskningsrelaterede spørgsmål og løse en række konkrete opgaver
relateret til forskning.
I 2014 afholdt Forskningsrådet 4 møder.
Sammensætning af Forskningsrådet:
3 professorer, 3 seniorforskere, 3 forskningsaktive med MVU-grunduddannelse samt hospitalets 2
sundhedsfaglige vicedirektører, hvoraf den forskningsansvarlige vicedirektør er formand.
Medlemmer af Forskningsråd Gentofte ultimo 2014
Vicedirektør, Lars Juhl Petersen (formand)
Vicedirektør, Jan Toftholm Andersen
Professor, overlæge dr.med., Lone Skov
Professor, overlæge, ph.d., Gunnar Gislason
Professor, overlæge dr.med. Tina Vilsbøll
Ledende overlæge, dr.med., Steen Stender
Overlæge, dr.med., Ole Rintek Madsen
Overlæge, dr.med., Anders Odgaard
Hospitalsdirektionen
Hospitalsdirektionen
Hud og Allergiafd.
Medicinsk afd. F
Klinisk biokemisk afd.
Medicinsk afd. C
Forskningsansvarlig sygeplejerske, cand.mag. Eline Noiesen
Medicinsk afd. F
Forskningsansvarlig sygeplejerske, MVO Ingelise Trosborg
Sygeplejerske, cand.cur, ph.d. stud. Kirsten Szöts
Lungemedicinsk afd.
Ordopædkirurgisk afd.
Forskningschef, specialeansvarlig overlæge, dr.med. Jüri Rumessen
Forskningsleder, ph.d., postdoc Hanne Konradsen
Forskningskonsulent, cand.scient.adm. Camilla Nymann
Forskningskonsulent, korrespondent Lone Falck
Forskningsenheden
Forskningsenheden
Forskningsenheden
Forskningsenheden
3
Forskningsenheden
Forskningsenheden bor i Kvalitet og Udvikling på adressen:
Kildegårdsvej 28, opg. 65, 1.th
2900 Hellerup
Forskningsenheden består af 4 medarbejdere:

Forskningschef Jüri Rumessen (specialeansvarlig overlæge, dr.med)
Tlf.:3867 3987

Tlf.: 3867 7250

hanne.konradsen@regionh.dk
Forskningskonsulent Camilla Nymann (Cand.scient.adm)
Tlf.: 3867 7228

jueri.johannes.rumessen@regionh.dk
Forskningsleder Hanne Konradsen (Med.HRD., cand.cur., ph.d, postdoc)
camilla.nymann@regionh.dk
Forskningskonsulent Lone Falck (Korrespondent, merkonom IT)
Tlf.: 3867 3988
lone.falck@regionh.dk
Ph.d. studiemiljø
Forskningsenheden administrerer et ph.d. studiemiljø i en
hyggelig kvistlejlighed på Kildegårdsvej 28, opg.65, 2. Her
findes faciliteter for studerende blandt hospitalets ansatte
læger, sygeplejersker og andet sundhedsfagligt personale:

6 arbejdspladser – heraf 5 udstyret med PC og fast IT
opkobling



Farveprinter, kopimaskine, telefon, div. kontorfaciliteter
Aflåselige arkivskabe
Minibibliotek med faste abonenmenter på en række
faglige tidsskrifter

Fælles mødelokale
Henvendelse: HGH-Forskning@regionh.dk
4
Forskerkarriereprogram på
Gentofte Hospital
Hospitalsdirektionen har afsat betydelige midler til konsolidering og udbygning af hospitalets forskerkarriereprogram. I fuldt udbygget form vil dette omfatte sammenhængende videnskabelige karrierespor på alle niveauer lige fra sundhedspersoner under uddannelse til akademiske slutstillinger. Den grundlæggende idé er forskningsdelestillinger og
uddannelse i forskningsledelse i sammenhæng og synergi med hospitalets kliniske funktioner.
Forskerdelestillinger
Hospitalsdirektionen har fra 2012 og frem afsat 5 mio. kr. årligt til oprettelse af delestillinger på hospitalet. Stillingerne indebærer delefunktion mellem 50 % klinisk arbejde
eller anden hidtidig beskæftigelse og 50 % forskning.
Delestillingerne repræsenterer en stor forskningssatsning for at imødekomme det store
behov for både forskerdelestillinger og for karrierespor for kvalificerede kliniske forskere
efter ph.d.-graden og på seniorforskerniveau.
Igangværende delestillinger som postdocs og seniorforskere ved Gentofte
Hospital 2014
5-årig seniorforsker delestilling


Thomas Almdal, overlæge, dr.med., Medicinsk afd. F
Peter Riis Hansen, overlæge, dr.med., Hjertemedicinsk afd.

Anders Odgaard, overlæge, dr.med., Ortopædkirurgisk afd.
4-årig postdoc delestilling


Hanne Konradsen, sygeplejerske, ph.d., Forskningsenheden i HR & Kvalitet
Lene Heise Garvey, overlæge, ph.d., Hud- og allergiafd.


Marianne Benn, overlæge, dr.med., Klinisk Biokemisk afd.
Ole Rintek, overlæge dr.med, Medicinsk afd. C



Lene Dreyer, overlæge, ph.d., Medicinsk afd. C
Paul F. Clementsen, overlæge, ph.d., Lungemedicinsk afd.
Jørgen Rungby, overlæge, dr.med., adj. professor, Medicinsk afd. F
5
Forskningspuljer 2014
I 2014 opdelte Forskningsrådet forskningspuljerne i en START-pulje for ansatte med MVU grunduddannelse og
en Strategisk forskningspulje for alle ansatte. Forskningsrådet lagde i sine bedømmelser vægt på, at projektet
passer ind i hospitalets overordnede strategiske prioritering.
START puljen 2014
Strategisk forskningspulje 2014
Kunne søges af alle ansatte på Gentofte Hospital.
STARTpuljen til anvendelse blandt ansatte med MVU
(Mellemlang Videregående Uddannelse) kunne i 2014
I Gentofte Hospitals strategi for forskning er et af
søges af både enkeltpersoner og afdelinger.
indsatsområderne prioritering af implementering af
forskningsresultater.
Midlerne tildeles spirende forskere og/eller forskningsområder, som ville have vanskeligt ved at opnå støtte
Puljens formål i 2014 var at støtte et eller flere
andetsteds, hvilket oftest svarer til 2-3 måneders løn.
forskningsprojekter med fokus på implementering
af forskningsresultater.
Uddelinger i 2014:
Puljen var på i alt kr. 300.00
 Behovsstyrede patientforløb
Lina Khoury, stud.scient.san.
Hud- og Allergiafdeling
Bevilget beløb: kr. 105.351

Uddelinger i 2014:
 Implementering af forskningsresultater
- en undersøgelse af implementeringspraksis på Gentofte Hospital
Et projekt i HR & Kvalitet
Nanna Kristensen
Udarbejdelse af to review artikler, der dokumenterer den eksisterende viden i forhold til ikke-medikamentel forebyggelse og
behandling af forstoppelse
Marie Louise Thise Rasmussen, sygeplejerske,
Master Public Health
Medicinsk afdeling F
 Implementeringsprocesser på en klinisk
biokemisk afdeling med fokus på tværfaglige implementeringer og Klinisk Biokemisk afdelings bidrag til optimering af
patientforløb
Et projekt i Klinisk Biokemisk afd.
 Vandladningsproblemer hos indlagte reumatologiske patienter
Pernille Friis Rønne, sygeplejerske, stud. Master
sundhedsantropologi
Medicinsk afdeling C
Eva Reinholdt m.fl.
6
Forskningens Døgn 2014
Forskningens Døgn den 24. april var en stor succes. Ca. 200 borgere lyttede til den nyeste viden
inden for sygdom og sundhed. Det skete ved en perlerække af foredrag med Gentofte Hospitals
fremmeste forskere i Store Auditorium. Borgerne fik mulighed for stille spørgsmål til forskerne om
deres forskellige indlæg og bud på, hvad vi skal forske i på Gentofte Hospital.
Forskningens Døgn er en landsdækkende begivenhed, hvor alle typer af forskningsinstitutioner
inviterer indenfor til en dag i forskningens tegn.
PROGRAM
Velkomst og praktisk info
Vicedirektør Lars Juhl Petersen
Hjerterytme-målinger hos vilde bjørne
Læge, ph.d. stud. Peter Godsk Jørgensen
Hvorfor giver tør hud eksem?
1. reservelæge, dr.med., ph.d., Jacob Thyssen
Hvorfor sover vi så dårligt på hospitalet?
Klinisk sygeplejespecialist, cand.mag. Eline Noiesen
Hurtigt ud af sengen efter hofteproteseoperation. Hvorfor
det?
Overlæge, dr.med. Søren Solgaard
Pause med åbne stande
Kan type 2-diabetes forebygges?
Professor, overlæge, dr.med. Tina Vilsbøll
Hvilke produkter giver parfumeallergi?
Læge, ph.d. Maria Vølund Heisterberg
Kan man minimere bivirkninger ved kolesterolsænkende
statinbehandling?
Ledende overlæge, dr.med. Steen Stender
Videnskabsjournalist og bl.a. kendt fra videnskabsprogrammer på DR, Anja Philip, var dagens
programvært. Hun bandt de forskellige oplæg
sammen.
7
I pausen kunne borgerne bl.a. få målt balance,
muskelstyrke, lungekapacitet, blodsukker, BMI
og prøve en ultralydskanning. Kræftens Bekæmpelse viste på en udendørs stand, hvordan kræft
og betændelse ser ud på et billede.
Forskningens Dag 2014
Forskningens Dag er et internt medarbejderarrangement, som Forskningsrådet afholdt den 26.
november 2014.
Det var endnu engang rekordernes dag: 64 abstracts blev præsenteret ved bemandede postere i auditoriebygningens forhal og 8 foredrag (udvalgt blandt 48 foredrags-ansøgninger).
Præmiesummen var i alt kr. 50.000.
Et dommerpanel gik diskret rundt og vurderede de mange flotte og videnstunge posters og lyttede
intenst til de 8 oplæg i auditoriet. Beslutningen var svær, men de velfortjente vindere af titlerne
dagens bedste to foredrag og bedste tre posters blev fundet.
Omtrent 150 forskere, studerende og andre nysgerrige sugede ny viden til sig under de interessante
foredrag, der gav stof til eftertanke.
Dagens første key note speaker var Mads Melbye,
professor, dr.med., og direktør National Sundhedsdokumentation og Forskning, Statens Serum Institut.
Mads Melbye talte om Danmark som laboratorium med de
mange unikke databaser over befolkningen
Dagens anden key note speaker var professor
Henning Boje Andersen fra Safety & Risk Management
Group, DTU Management Engineering.
VINDERNE
1. præmie foredrag på kr. 25.000 gik til
Ann-Marie Malby Schoos, Copsac, Hud- og
Allergiafd.
2. præmie foredrag på kr. 10.000 gik til
Ulrich Rohde, Center for Diabetes, Medicinsk
afd. F
Posterpræmier á kr. 5.000 gik til:
- Sidse Graff Jensen, Lungemedicinsk afd.
- Kasper Søndergaard, Medicinsk afd. C
- Johannes Waage, Copsac, Hud- &
Allergiafd.
8
Forskningstemaer, -personale og
-publikationslister 2014
Forskningspublikationerne udgået fra Gentofte Hospital i 2014 er oprettet i og trukket fra forskningsregistreringssystemet PURE, der blev indført i Region Hovedstaden i 2010.
I grafer og på publikationslisterne vises kun afdelingernes indberetning i PURE indenfor kategorien peer
reviewed forskning udgivet i 2014. Derfor er alle publikationer på listen pointgivende i regionens forskningsevaluering. Da vi har et stort samarbejde på tværs af afdelingerne, kan den samme publikation være
registreret i publikationslisten på flere afdelinger, hvorfor en sammenlægning af alle afdelingernes publikationsantal være lidt højere end den samlede total for Gentofte, idet de tværgående publikationer kun
tælles med én gang i Gentofte-totalen.
Publikationernes individuelle bibliometriske identifikation er også medtaget.
Nedenstående diagram viser fordeling af peer-reviewede tidsskriftsartikler udgået fra Gentofte Hospital i
2014 fordelt på afdelinger. Se nærmere specifikationer i de følgende afsnit.
Kilde:
Kilde: PURE rapport trukket i rapportmodul juli 2015
9
Anæstesi afd.
Forskningstemaer
 Genoplivede hypotermi behandlede patienter efter
hjertestop; 7- og 30 dages mortalitet

NAPS (nurse administrated propofol sedation); opgørelse af hypoxi episoder og relation til søvnapnø

Ultralydsvejledte nerveblokader
Videnskabelige medarbejdere
Nina Vendel Jensen, forsknings- og operationssygeplejerske
Forskningsansvarlig overlæge
Ulrik Grevstad, overlæge
Forskningsansvarlig sygeplejerske
Maria Bergholt, klinisk sygeplejespecialist
Publikationer 2014
1.
Espelund M, Grevstad U, Jaeger P, Hölmich P, Kjeldsen LE, Mathiesen O et al.
Adductor canal blockade for moderate to severe pain after arthroscopic knee
surgery: a randomized controlled trial. Acta anaesthesiologica Scandinavica.
2014 nov;58(10):1220-7. Tilgængelig fra: 10.1111/aas.12407
2.
Grevstad U, Mathiesen O, Lind T, Dahl JB. Effect of adductor canal block on
pain in patients with severe pain after total knee arthroplasty: a randomized
study with individual patient analysis. British Journal of Anaesthesia. 2014 jan
8;112(5):912-19. Tilgængelig fra: 10.1093/bja/aet441
3.
Konradsen H, Trosborg I, Christensen L, Pedersen PU. Evaluation of interrater
reliability assessing oral health in acute care settings. International Journal of
Nursing Practice. 2014;20:258. Tilgængelig fra: 10.1111/ijn.12140
4.
Konradsen H, Trosborg I, Christensen L, Thomsen T, Pedersen PU. Who needs
oral care? A study of potential factors associated with the need for oral care.
Journal of Nursing Education and Practice. 2014;4(11):16-22. Tilgængelig fra:
http://dx.doi.org/10.5430/jnep.v4n11p16
5.
Ravn P, Foster DJR, Kreilgaard M, Christrup L, Werner MU, Secher EL et al.
Pharmacokinetic-pharmacodynamic modelling of the analgesic and antihyperalgesic effects of morphine after intravenous infusion in human volunteers. Basic
& clinical pharmacology & toxicology. 2014 sep;115(3):257-67. Tilgængelig fra:
10.1111/bcpt.12213
10
Ernæringsenheden
i Serviceafdelingen
Publikationer 2014
1.
Aller EEJG, Larsen TM, Holst C, Lindroos AK, Kafatos A, Pfeiffer A et al.
Weight loss maintenance in overweight subjects on ad libitum diets with high or
low protein content and glycemic index: the DIOGENES trial 12-month results.
International journal of obesity (2005). 2014 mar 28;38(12):1511-1517. Tilgængelig fra: 10.1038/ijo.2014.52
2.
Ankarfeldt MZ, Ängquist LH, Stocks T, Jakobsen MU, Overvad K, Halkjær J et
al. Body Composition, Dietary Protein and Body Weight Regulation. Reconciling
Conflicting Results from Intervention and Observational Studies?. P L o S One.
2014;9(7):e101134. Tilgængelig fra: 10.1371/journal.pone.0101134
3.
Ankarfeldt MZ, Ängquist LH, Jakobsen MU, Overvad K, Tjønneland A, Halkjaer
J et al. Interactions of dietary protein and adiposity measures in relation to subsequent changes in body weight and waist circumference. Obesity (Silver
Spring, Md.). 2014 jun 19;22(9):2097–2103. Tilgængelig fra: 10.1002/oby.20812
4.
Geiker N, Myint KS, Heck P, Dhatariya K, Hørup Larsen SM, Andersen MR et
al. Intentional Weight Loss Improved Performance in Obese Ischaemic Heart
Patient: A Two Centre Intervention Trial. Jacobs journal of food and nutrition.
2014;1(1). 003.
5.
Hare KJ, Bonde L, Svare JA, Randeva HS, Asmar M, Hørup Larsen SM et al.
Decreased plasma chemerin levels in women with gestational diabetes mellitus.
Diabetic Medicine Online. 2014 aug;31(8):936-40. Tilgængelig fra:
10.1111/dme.12436
6.
Jensen P, Zachariae C, Christensen R, Geiker NRW, Schaadt BK, Stender S et
al. Effect of Weight Loss on the Cardiovascular Risk Profile of Obese Patients
with Psoriasis. Acta Dermatovenereologica. 2014 feb 20;94(6):691-4.
Tilgængelig fra: 10.2340/00015555-1824
11
Forskningsenheden
i Kvalitet og Udvikling
Forskningstemaer

5.
Noiesen E, Trosborg I, Bager L, Herning M, Lyngby C, Konradsen H. Constipation prevalence and incidence among medical patients acutely admitted to hospital with
a medical condition. Journal of Clinical Nursing. 2014 aug 1;23(15-16):2295-2302.
Tilgængelig fra: 10.1111/jocn.12511
6.
Szöts K, Konradsen H, Solgaard S, Ostergaard B. Telephone follow-up by nurse
following total knee arthroplasty - protocol for a randomized clinical trial (NCT
01771315). B M C Nursing. 2014;13:14. Tilgængelig fra: 10.1186/1472-6955-13-14
7.
Telinius N, Baandrup U, Rumessen J, Pilegaard H, Hjortdal VE, Aalkjaer C et al.
The human thoracic duct is functionally innervated by adrenergic nerves. A J P:
Heart and Circulatory Physiology (Online). 2014 jan;306(2):H206-13. Tilgængelig
fra: 10.1152/ajpheart.00517.2013
Klinisk og epidemiologisk forskning i cøliaki og
malabsorption

Grundvidenskabelige og translatoriske forskningsprojekter vedrørende strukturel cellebiologi og
glatmuskelfunktion

Deskriptive studier af patientkarakteristika

Evaluering af patientnære screeningsprogrammer

Klinisk randomiserede sygeplejeinterventioner

Forskningsmetode udvikling

Klinisk og epidemiologisk forskning i tuberkulose

Implementeringsforskning: hvorledes der på ud-
Kommentar/debat
8.
valgte kliniske afdelinger arbejdes med implementering af evidensbaserede forskningsresultater
Wildt S, Lassen IN, Rumessen JJ. Incorrect citation and analysis in meta-analysis.
Inflammatory Bowel Diseases. 2014;20(12):E25. Tilgængelig fra:
10.1097/MIB.0000000000000249
Bidrag til bog/antologi
Hanne Konradsen, Forskningsleder, sygeplejer-
9.
ske, cand.cur. ph.d.
Jüri Rumessen, Forskningschef, dr. med.
Nanna Kristensen, cand.psych. og organisationskonsulent
Publikationsliste 2014
1.
Hansen C, Konradsen H, Abrahamsen B, Pedersen B. Women’s experiences of
their osteoporosis diagnosis at the time of diagnosis and six months later: a
Phenomenological-hermeneutic Study. International Journal of Qualitative Studies on Health and Well-Being. 2014;22438. Tilgængelig fra:
doi.org/10.3402/qhw.v9.22438
2.
Konradsen H, Lillebaek T, Wilcke JTR, Lomborg K. Being publicly diagnosed: A
grounded theory study of Danish patients with tuberculosis. International Journal of Qualitative Studies on Health and Well-Being. 2014;9:1-8.
3.
Konradsen H, Trosborg I, Christensen L, Pedersen PU. Evaluation of interrater
4.
Konradsen H, Trosborg I, Christensen L, Thomsen T, Pedersen PU. Who needs
12
Konradsen H. Et ændret body image. I Wittrup, Prip, Grube, red., Kræftsygepleje i
et forløbsperspektiv. Munksgård Danmark. 2014. s. 111-119.
Forskningstemaer
seniorforskere, ph.d.-studerende, skolarstipendiater,
På Hjertemedicinsk Afdeling P forskes både klinisk i
og forskningssygeplejersker.
diagnostik, behandling og pleje af de sygdomme, af-
Afdelingen har en del samarbejdspartnere inklusiv
delingen som invasivt hjertecenter i Region Hoved-
afdelingerne Medicinsk F og C samt Hud- og Allergi på
staden varetager behandling af, samt i hjertesyg-
Gentofte Hospital, Steno Diabetes Center, Institut for
dommes epidemiologi og behandling med anvendelse
Eksperimentel Medicin på Århus Universitet, Panumin-
af de danske landsdækkende registre.
stituttet samt hjerteafdelingerne på Rigshospitalet og
De væsentligste fokusområder er:
Skejby Sygehus. Derudover har afdelingen et bredt
internationalt samarbejde i USA og Europa, hvor flere

Diagnostik og behandling af iskæmisk hjertesygdom, hvor nye biokemiske og billeddiagnostiske
teknikker med ekkokardiografi og CT- og MR-

forskere fra afdelingen er udstationerede ved prestigefyldte institutioner og universiteter bl.a. ved Stanford,
scanning, samt ny medicin og nye teknikker ved
Duke, Vanderbilt, Framingham, Harvard, Rochester,
ballonudvidelser undersøges.
Barts and the London School of Medicine og Birming-
Store epidemiologiske undersøgelser, specielt in-
ham.
den for området kardiovaskulær farmakoepidemiologi, hvor de store danske registre, især
Landspatientregisteret, Dansk Hjerteregister og
Lægemiddelstatistikregisteret, anvendes.

Ekkokardiografisk vejledt behandling af svært
Der udgår årligt fra afdelingen 130-150 videnskabelige artikler i internationale peer reviewed
tidsskrifter samt 6-7 ph.d.-afhandlinger.
hjertesvigt med biventrikulær pacemaker eller
ICD enhed.
Forskningen finansieres dels via de store fonde, dels

Tidlig opsporing af hjertesygdom ved diabetes.
via samarbejde med industrien.

Sammenhængen mellem inflammation og hjertesygdom.

Diagnostik og behandling af infektiøs endokarditis
(hjerteklap-betændelse).

Afdelingen blev i 2011 – som eneste hjerteafdeling i Danmark - udnævnt til Center of Global
Afdelingen er påbegyndt et meget omfattende
Excellence for forskning, patientbehandling og
projekt inden for genetisk epidemiologi ved hjer-
pleje i international særklasse.
tesygdom, ligesom undersøgelser af nye teknikker


ved kateterbaseret radiofrekvensablation (over-
brænding) af hurtige hjerterytme-forstyrrelser er i
Professorer
planlægningsfasen.
Jan Skov Jensen, ledende overlæge, ph.d., dr.
Sygeplejebaserede registerstudier om patienters
med.
selvvurderede helbred ved udskrivelse fra hjerte-
Gunnar Gislason, overlæge, ph.d.
center.
Niels Eske Bruun, overlæge, dr.med.
Kvalitativt baseret sygeplejeforskning med fokus
på patienters oplevelse i forbindelse med at have
Kliniske forskningslektor og
en hjertesygdom.
Seniorforsker delestilling
Peter R. Hansen, overlæge, dr.med., ph.d.
Afdelingen har to professorer ved Købehavns Universitet: Ledende overlæge, dr.med., ph.d. Jan Skov
Seniorforskere/Post.docs
Jensen, og overlæge, ph.d. Gunnar Gislason. Gunnar
Christian Torp-Pedersen, professor
Selina Kikkenborg Berg, ph.d.,
Gislason er også adjungeret professor ved Syddansk.
post.doc./projektleder
Overlæge, dr.med. Niels Eske Bruun er adjungeret
Christian Jøns, 1. reservelæge, ph.d.
professor ved Aalborg Universitet. Overlæge,
Rasmus Møgelvang, 1. reservelæge, ph.d.
dr.med., ph.d, Peter Riis Hansen er klinisk forsk-
Morten Lock Hansen, 1. reservelæge, ph.d.
ningslektor ved Københavns Universitet. Derudover
Fredrik Folke, 1. reservelæge, ph.d.
er der i afdelingen ansat en meget stor stab af
Rikke Sørensen, 1. reservelæge, ph.d
13
Charlotte Andersson, ph.d., post.doc
Andet forskningsaktivt personale
Speciallæger
Ph.d. studerende
Jan Kyst Madsen, overlæge, dr. med.
Helle Carstensen
Ulrik Abildgaard, overlæge, dr. med.
Magnus Thorsten Jensen
Jan Bech, overlæge, ph.d.
Jacob Sivertsen
Søren Galatius, overlæge, dr. med.
Peter Weeke
Jim Hansen, overlæge, dr. med.
Søren Østergaard Lindberg
Thomas Fritz Hansen, overlæge
Peter Godsk Jørgensen
Jens Haarbo, overlæge, dr. med.
Tor Biering-Sørensen
Michael Vinther, overlæge, ph.d.
Carolina Malta Hansen
Arne Johannessen, overlæge, dr. med.
Deniz Karasoy
Peter Skøtt, overlæge, dr. med.
Martin Huth Ruwald
René Worck, overlæge, ph.d.
Morten Lamberts
Tommi Bo Lindhardt, overlæge, ph.d.
Mads Wissenberg Jørgensen
Charlotte Larroudé, afdelingslæge, ph.d.
Jacob Schmidt
Jørgen K. Kanters, lektor ved Københavns Universitet
Kim Wadt Hansen
– tilknyttet elektrofysiologisøjle
Adam Pena
Louise Eske Bruun
Sygeplejersker
Anders Dahl
Margrethe Herning, klinisk sygeplejespecialist
Trine Kiilerich Lauridsen
Stefan Christensen
Projektsygeplejersker/bioanalytikere
Søren Lund Kristensen
Camilla Böhne, projektsygeplejerske
Lars Lindberg Sørensen
Lena Fahlström, projektsygeplejerske
Michelle Schmiegelow
Henriette Bjørnager Jensen, projektsygeplejerske
Anne-Marie Schjerning Olsen
Ulla H. Jakobsen, projektsygeplejerske
Karl Emil Kristensen
Gitte von Jessen, projektsygeplejerske
Martina de Knegt
Julie Laage-Petersen, projektsygeplejerske
Christina Alhede
Jette S. Madsen, projektsygeplejerske
Gorm Mørk Hansen
Lene Høgh Simonsen, projektsygeplejerske
Shahzleen Rajan
Flemming Bjerre, projektsygeplejerske
Kathrine Bach Søndergaard
Britt Falskov
Jonas Bjerring Olesen
Jan Skov Jensen, ledende overlæge, professor, ph.d.,
Charlotte Mérie
dr.med.
Jesper Lindhardsen
Anne Gjesing Olesen
Anne Christine Huth Ruwald
Margrethe Herning, forskningsansvarlig sygeplejerske, MSU
Skolarstipendiater / studenter
Jonas Krogh Jensen
Publikationsliste 2014
Thomas Bo Jensen
Aziza Azimi
1.
Ahlehoff O, Gislason G, Hansen PR. Cardiovascular aspects of psoriasis: an
updated review. International Journal of Dermatology. 2014 jun;53(6):e337.
Tilgængelig fra: 10.1111/ijd.12267
2.
Ahlehoff O, Skov L, Gislason G, Gniadecki R, Iversen L, Bryld LE et al. Cardiovascular outcomes and systemic anti-inflammatory drugs in patients with severe psoriasis: 5-year follow-up of a Danish nationwide cohort. Journal of the
European Academy of Dermatology and Venereology : JEADV. 2014 okt 10.
Tilgængelig fra: 10.1111/jdv.12768
3.
Andersen TR, Schmidt JF, Thomassen M, Hornstrup T, Frandsen U, Randers
MB et al. A preliminary study: effects of football training on glucose control,
body composition, and performance in men with type 2 diabetes. Scandinavian
journal of medicine & science in sports. 2014 aug;24 Suppl 1:43-56.
Tilgængelig fra: 10.1111/sms.12259
Anders Mikkelsen
Esma Salahadeen
Morten Winther Hvidtfeldt
Signe Abitz Winther
Maria Dons
Flemming Javier Olsen
Lena Karlsson
Anna-Karin Numé
Anna Sofia Larsson
Anders Nissen Bonde
14
4.
Andersen LJ, Randers MB, Hansen PR, Hornstrup T, Schmidt JF, Dvorak J et
al. Structural and functional cardiac adaptations to 6 months of football training
in untrained hypertensive men. Scandinavian journal of medicine & science in
sports. 2014 aug;24 Suppl 1:27-35. Tilgængelig fra: 10.1111/sms.12237
5.
Andersson C, Gislason GH, Hlatky MA, Søndergaard KB, Pallisgaard J, Smith
JG et al. A risk score for predicting 30-day mortality in heart failure patients undergoing non-cardiac surgery. European Journal of Heart Failure. 2014
dec;16(12):1310-6. Tilgængelig fra: 10.1002/ejhf.182
6.
Andersson C, Mérie C, Jørgensen M, Gislason GH, Torp-Pedersen C, Overgaard C et al. Association of β-Blocker Therapy With Risks of Adverse Cardiovascular Events and Deaths in Patients With Ischemic Heart Disease Undergoing Noncardiac Surgery: A Danish Nationwide Cohort Study. JAMA internal
medicine. 2014;174(3):336-344. Tilgængelig fra:
10.1001/jamainternmed.2013.11349
7.
8.
9.
19. Berg SK, Svanholm JR, Lauberg A, Borregaard B, Herning M, Mygind A et al.
Patient-reported outcomes at hospital discharge from Heart Centres, a national
cross-sectional survey with a register-based follow-up: the DenHeart study protocol. B M J Open. 2014;4(5):e004709. Tilgængelig fra: 10.1136/bmjopen-2013004709
20. Biering-Sørensen T, Jensen JS, Pedersen S, Galatius S, Hoffmann S, Jensen MT
et al. Doppler Tissue Imaging Is an Independent Predictor of Outcome in Patients
with ST-Segment Elevation Myocardial Infarction Treated with Primary Percutaneous Coronary Intervention. Journal of the American Society of Echocardiography :
official publication of the American Society of Echocardiography. 2014
mar;27(3):258-67. Tilgængelig fra: 10.1016/j.echo.2013.11.005
21. Biering-Sørensen T, Hoffmann S, Mogelvang R, Zeeberg Iversen A, Galatius S,
Hansen TF et al. Myocardial strain analysis by 2-dimensional speckle tracking
echocardiography improves diagnostics of coronary artery stenosis in stable angina pectoris. Circulation. Cardiovascular Imaging. 2014 jan 1;7(1):58-65.
Tilgængelig fra: 10.1161/CIRCIMAGING.113.000989
Andersson C, Shilane D, Go AS, Chang TI, Kazi D, Solomon MD et al. Betablocker therapy and cardiac events among patients with newly diagnosed coronary heart disease. Journal of the American College of Cardiology. 2014 jul
22;64(3):247-52. Tilgængelig fra: 10.1016/j.jacc.2014.04.042
22. Blicher TM, Hommel K, Kristensen SL, Torp-Pedersen C, Madsen M, Kamper AL
et al. Benefit of clopidogrel therapy in patients with myocardial infarction and
chronic kidney disease-a Danish nation-wide cohort study. J.Am.Heart Assoc.
2014 aug;3(4):1-10. Tilgængelig fra: doi: 10.1161/JAHA.114.001116
Andersson C, Vasan RS. Compiling the complement of genes implicated in coronary artery disease. Circulation. Cardiovascular genetics. 2014 dec;7(6):73840. Tilgængelig fra: 10.1161/CIRCGENETICS.114.000909
23. Bligaard N, Thuesen L, Saunamäki K, Thayssen P, Aarøe J, Hansen PR et al.
Similar five-year outcome with paclitaxel- and sirolimus-eluting coronary stents.
Scandinavian cardiovascular journal : SCJ. 2014 jun;48(3):148-55. Tilgængelig
fra: 10.3109/14017431.2014.883461
Andersson C, Vasan RS. Epidemiology of heart failure with preserved ejection
fraction. Heart Failure Clinics. 2014 jul;10(3):377-88. Tilgængelig fra:
10.1016/j.hfc.2014.04.003
24. Bonde AN, Lip GYH, Kamper A-L, Hansen PR, Lamberts M, Hommel K et al. Net
Clinical Benefit of Antithrombotic Therapy in Patients With Atrial Fibrillation and
Chronic Kidney Disease: A Nationwide Observational Cohort Study. Journal of the
American College of Cardiology. 2014 dec 16;64(23):2471-82. Tilgængelig fra:
10.1016/j.jacc.2014.09.051
10. Andersson C, Vasan RS. Is there a role for coronary artery calcium scoring for
management of asymptomatic patients at risk for coronary artery disease?: Clinical risk scores are sufficient to define primary prevention treatment strategies
among asymptomatic patients. Circulation. Cardiovascular Imaging. 2014
mar;7(2):390-7; discussion 397. Tilgængelig fra:
10.1161/CIRCIMAGING.113.000470
11. Andersson C, Jørgensen ME, Martinsson A, Hansen PW, Gustav Smith J, Jensen PF et al. Noncardiac surgery in patients with aortic stenosis: a contemporary study on outcomes in a matched sample from the Danish health care system.
Clinical Cardiology (Hoboken). 2014 nov;37(11):680-6. Tilgængelig fra:
10.1002/clc.22324
25. Borgquist R, Haugaa KH, Gilljam T, Bundgaard H, Hansen J, Eschen O et al. The
diagnostic performance of imaging methods in ARVC using the 2010 Task Force
criteria. European heart journal cardiovascular Imaging. 2014 nov;15(11):1219-25.
Tilgængelig fra: 10.1093/ehjci/jeu109
26. Bruun NE, Habib G, Thuny F, Sogaard P. Cardiac imaging in infectious endocarditis. European Heart Journal. 2014 mar;35(10):624-632. Tilgængelig fra:
10.1093/eurheartj/eht274
27. Bølling R, Scheller NM, Køber L, Poulsen HE, Gislason GH, Torp-Pedersen C.
Comparison of the clinical outcome of different beta-blockers in heart failure patients: a retrospective nationwide cohort study. European Journal of Heart Failure.
2014 jun;16(6):678-684. Tilgængelig fra: 10.1002/ejhf.81
12. Asferg CL, Nielsen SJ, Andersen UB, Linneberg A, Møller DV, Hedley PL et al.
Metabolic Rather Than Body Composition Measurements Are Associated With
Lower Serum Natriuretic Peptide Concentrations in Normal Weight and Obese
Men. American Journal of Hypertension. 2014 apr;27(4):620-627. Tilgængelig
fra: 10.1093/ajh/hpt145
28. Carlson N, Dixen U, Marott JL, Jensen MT, Jensen GB. Predictive value of casual
ECG-based resting heart rate compared with resting heart rate obtained from
Holter recording. Scandinavian Journal of Clinical & Laboratory Investigation. 2014
mar;74(2):163-9. Tilgængelig fra: 10.3109/00365513.2013.867531
13. Bang CN, Gerdts E, Aurigemma GP, Boman K, de Simone G, Dahlöf B et al.
Four-group classification of left ventricular hypertrophy based on ventricular
concentricity and dilatation identifies a low-risk subset of eccentric hypertrophy
in hypertensive patients. Circulation. Cardiovascular Imaging. 2014
maj;7(3):422-9. Tilgængelig fra: 10.1161/CIRCIMAGING.113.001275
29. Christensen L, Krieger DW, Højberg S, Pedersen OD, Karlsen FM, Jacobsen MD
et al. Paroxysmal atrial fibrillation occurs often in cryptogenic ischaemic stroke. Final results from the SURPRISE study. European journal of neurology : the official
journal of the European Federation of Neurological Societies. 2014 jun;21(6):8849. Tilgængelig fra: 10.1111/ene.12400
14. Bang CN, Gislason GH, Greve AM, Bang CA, Jørgensen AL, Torp-Pedersen C
et al. New-onset atrial fibrillation is associated with cardiovascular events leading to death in a first time myocardial infarction population of 89,703 patients
with long-term follow-up: a nationwide study. Journal of the American Heart Association. 2014 feb;3(1):e000382. Tilgængelig fra: 10.1161/JAHA.113.000382
15. Bang CN, Okin PM, Køber L, Wachtell K, Gottlieb AB, Devereux RB. Psoriasis
is associated with subsequent atrial fibrillation in hypertensive patients with left
ventricular hypertrophy: the Losartan Intervention For Endpoint study. Journal of
hypertension. 2014 mar;32(3):667-72. Tilgængelig fra:
10.1097/HJH.0000000000000078
16. Bang CN, Greve AM, Køber L, Rossebø AB, Ray S, Boman K et al. Reninangiotensin system inhibition is not associated with increased sudden cardiac
death, cardiovascular mortality or all-cause mortality in patients with aortic stenosis. International Journal of Cardiology. 2014 aug 20;175(3):492-8.
Tilgængelig fra: 10.1016/j.ijcard.2014.06.013
30. Christiansen M, Hedley PL, Theilade J, Stoevring B, Leren TP, Eschen O et al.
Mutations in Danish patients with long QT syndrome and the identification of a
large founder family with p.F29L in KCNH2. B M C Medical Genetics. 2014;15:31.
Tilgængelig fra: 10.1186/1471-2350-15-31
31. Darkner S, Chen X, Hansen J, Pehrson S, Johannessen A, Nielsen JB et al.
Recurrence of arrhythmia following short-term oral AMIOdarone after CATheter
ablation for atrial fibrillation: a double-blind, randomized, placebo-controlled study
(AMIO-CAT trial). European Heart Journal. 2014 dec 14;35(47):3356-64. Tilgængelig fra: 10.1093/eurheartj/ehu354
32. de Knegt MC, Biering-Sørensen T, Søgaard P, Sivertsen JC, Jensen JS, Møgelvang R. Concordance and reproducibility between M-mode, tissue Doppler imaging, and two-dimensional strain imaging in the assessment of mitral annular displacement and velocity in patients with various heart conditions. European Heart
Journal Cardiovascular Imaging. 2014 jan;15(1):62-9. Tilgængelig fra:
10.1093/ehjci/jet119
17. Bang CN, Gislason GH, Greve AM, Torp-Pedersen C, Køber L, Wachtell K.
Statins reduce new-onset atrial fibrillation in a first-time myocardial infarction
population: a nationwide propensity score-matched study. European journal of
preventive cardiology. 2014 mar;21(3):330-8. Tilgængelig fra:
10.1177/2047487312462804
33. Demant MN, Gislason GH, Køber L, Vaag A, Torp-Pedersen C, Andersson C.
Association of heart failure severity with risk of diabetes: a Danish nationwide cohort study. Diabetologia. 2014 aug;57(8):1595-600. Tilgængelig fra:
10.1007/s00125-014-3259-z
18. Bang UC, Hyldstrup L, Jensen JEB. The impact of recombinant parathyroid
hormone on malignancies and mortality: 7 years of experience based on nationwide Danish registers. Osteoporosis international : a journal established as
result of cooperation between the European Foundation for Osteoporosis and
the National Osteoporosis Foundation of the USA. 2014;25:639-644.
Tilgængelig fra: 10.1007/s00198-013-2470-y
34. D'Souza M, Saaby L, Poulsen TS, Diederichsen ACP, Hosbond SE, Diederichsen
SZ et al. Comparison of mortality in patients with acute myocardial infarction accidentally admitted to non-cardiology departments versus that in patients admitted
to coronary care units. The American journal of cardiology. 2014 okt
15;114(8):1151-7. Tilgængelig fra: 10.1016/j.amjcard.2014.07.035
15
35. Ejlskov L, Mortensen RN, Overgaard C, Christensen L, Vardinghus-Nielsen H,
Kræmer SRJ et al. Individual social capital and survival: a population study with
5-year follow-up. B M C Public Health. 2014;14:1025. Tilgængelig fra:
10.1186/1471-2458-14-1025
52. Jensen P, Zachariae C, Christensen R, Geiker NRW, Schaadt BK, Stender S et al.
Effect of Weight Loss on the Cardiovascular Risk Profile of Obese Patients with
Psoriasis. Acta Dermatovenereologica. 2014 feb 20;94(6):691-4. Tilgængelig fra:
10.2340/00015555-1824
53. Jensen MT, Sogaard P, Andersen HU, Bech J, Hansen TF, Galatius S et al.
Prevalence of systolic and diastolic dysfunction in patients with type 1 diabetes
without known heart disease: the Thousand & 1 Study. Diabetologia. 2014
apr;57(4):672-80. Tilgængelig fra: 10.1007/s00125-014-3164-5
36. Ekeløf S, Rosenberg J, Jensen JS, Gögenur I. Pharmacological attenuation of
myocardial reperfusion injury in a closed-chest porcine model: a systematic review. Journal of Cardiovascular Translational Research. 2014 aug;7(6):570-80.
Tilgængelig fra: 10.1007/s12265-014-9574-4
37. Ersbøll M, Valeur N, Hassager C, Søgaard P, Køber L. The association between renal impairment and cardiac structure and function in patients with acute
myocardial infarction. American heart journal. 2014 apr;167(4):506-13.
Tilgængelig fra: 10.1016/j.ahj.2013.12.029
38. Faber J, Selmer C. Cardiovascular disease and thyroid function. Cardiovascular
Issues in Endocrinology. 2014;43:45-56. Tilgængelig fra: 10.1159/000360558
39. Fosbøl EL, Olsen A-MS, Olesen JB, Andersson C, Kober L, Torp-Pedersen C et
al. Use of nonsteroidal anti-inflammatory drugs among healthy people and specific cerebrovascular safety. International Journal of Stroke. 2014 okt
9;9(7):943-5. Tilgængelig fra: 10.1111/j.1747-4949.2012.00863.x
40. Gaïni S, Bruun NE, Kollslíð R, Thomsen H, á Steig T, Nielsen KR et al.
Whipple's disease involving the eye, the brain, the heart and the gut diagnosed
through the eye. Acta Ophthalmologica (Online). 2014 dec;92(8):e693-4. Tilgængelig fra: 10.1111/aos.12454
54. Jespersen L, Abildstrom SZ, Hvelplund A, Madsen JK, Galatius S, Pedersen F et
al. Burden of Hospital Admission and Repeat Angiography in Angina Pectoris Patients with and without Coronary Artery Disease: A Registry-Based Cohort Study.
P L o S One. 2014 apr 4;9(4):e93170. Tilgængelig fra:
10.1371/journal.pone.0093170
55. Jespersen L, Abildstrøm SZ, Peña A, Hansen PR, Prescott E. Predictive value of
the corrected TIMI frame count in patients with suspected angina pectoris but no
obstructive coronary artery disease at angiography. Clinical research in cardiology
: official journal of the German Cardiac Society. 2014 jan 20;103(5):381-387.
56. Johnsen SP, Svendsen MLO, Hansen ML, Brandes A, Mehnert F, Husted SE.
Preadmission oral anticoagulant treatment and clinical outcome among patients
hospitalized with acute stroke and atrial fibrillation: a nationwide study. Stroke; a
journal of cerebral circulation. 2014 jan;45(1):168-75. Tilgængelig fra:
10.1161/STROKEAHA.113.001792
41. Geiker N, Myint KS, Heck P, Dhatariya K, Hørup Larsen SM, Andersen MR et
al. Intentional Weight Loss Improved Performance in Obese Ischaemic Heart
Patient: A Two Centre Intervention Trial. Jacobs journal of food and nutrition.
2014;1(1). 003.
57. Jørgensen PG, Jensen JS, Marott JL, Jensen GB, Appleyard M, Mogelvang R.
Electrocardiographic changes improve risk prediction in asymptomatic persons
age 65 years or above without cardiovascular disease. Journal of the American
College of Cardiology. 2014 sep 2;64(9):898-906. Tilgængelig fra:
10.1016/j.jacc.2014.05.050
42. Gjesing A, Gislason GH, Køber L, Gustav Smith J, Christensen SB, Gustafsson
F et al. Nationwide trends in development of heart failure and mortality after
first-time myocardial infarction 1997-2010: A Danish cohort study. European
journal of internal medicine. 2014 okt;25(8):731-8. Tilgængelig fra:
10.1016/j.ejim.2014.08.009
58. Jørgensen TSH, Hansen AH, Sahlberg M, Gislason GH, Torp-Pedersen C,
Andersson C et al. Falls and comorbidity: The pathway to fractures. Scandinavian
journal of public health. 2014 maj;42(3):287-94. Tilgængelig fra:
10.1177/1403494813516831
59. Jørgensen PG, Arnemo J, Swenson JE, Jensen JS, Galatius S, Frøbert O. Low
cardiac output as physiological phenomenon in hibernating, free-ranging Scandinavian brown bears (Ursus arctos) - an observational study. Cardiovascular Ultrasound. 2014;12:36. Tilgængelig fra: 10.1186/1476-7120-12-36
43. Greve AM, Dalsgaard M, Bang CN, Egstrup K, Ray S, Boman K et al. Stroke in
patients with aortic stenosis: the Simvastatin and Ezetimibe in Aortic Stenosis
study. Stroke; a journal of cerebral circulation. 2014 jul;45(7):1939-46. Tilgængelig fra: 10.1161/STROKEAHA.114.005296
44. Greve AM, Dalsgaard M, Bang CN, Egstrup K, Rossebø AB, Boman K et al.
Usefulness of the electrocardiogram in predicting cardiovascular mortality in
asymptomatic adults with aortic stenosis (from the Simvastatin and Ezetimibe in
Aortic Stenosis Study). The American journal of cardiology. 2014 sep
1;114(5):751-6. Tilgængelig fra: 10.1016/j.amjcard.2014.06.006
45. Gyldenløve M, Jensen P, Linneberg A, Thyssen JP, Zachariae C, Hansen PR et
al. Psoriasis and the Framingham risk score in a Danish hospital cohort. International Journal of Dermatology. 2014 sep;53(9). Tilgængelig fra:
10.1111/ijd.12196
46. Gyldenløve M, Jensen P, Løvendorf MB, Zachariae C, Hansen PR, Skov L.
'Short-term treatment with methotrexate does not affect microvascular endothelial function in patients with psoriasis'. Journal of the European Academy of
Dermatology and Venereology : JEADV. 2014 feb 21;1-4. Tilgængelig fra:
10.1111/jdv.12385
47. Hansen GM, Holmstrup P, Tolker-Nielsen T, Køllgaard TMS, Nielsen CH, Givskov M et al. Mulig sammenhæng mellem marginal parodontitis og iskæmisk
hjertesygdom. Ugeskrift for læger [online]. 2014 maj 2.
48. Hedley PL, Carlsen AL, Christiansen KM, Kanters JK, Behr ER, Corfield VA et
al. MicroRNAs in cardiac arrhythmia: DNA sequence variation of MiR-1 and
MiR-133A in long QT syndrome. Scandinavian Journal of Clinical & Laboratory
Investigation. 2014 sep;74(6):485-91. Tilgængelig fra:
10.3109/00365513.2014.905696
60. Jørgensen ME, Torp-Pedersen C, Gislason GH, Jensen PF, Berger SM, Christiansen CB et al. Time elapsed after ischemic stroke and risk of adverse cardiovascular events and mortality following elective noncardiac surgery. JAMA : the journal of the American Medical Association. 2014 jul 16;312(3):269-77. Tilgængelig
fra: 10.1001/jama.2014.8165
61. Jørgensen CH, Gislason GH, Ahlehoff O, Andersson C, Torp-Pedersen C, Hansen
PR. Use of secondary prevention pharmacotherapy after first myocardial infarction
in patients with diabetes mellitus. B M C Cardiovascular Disorders. 2014;14:4.
Tilgængelig fra: 10.1186/1471-2261-14-4
62. Kanters JK, Yuan L, Hedley PL, Stoevring B, Jons C, Bloch Thomsen PE et al.
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18
Letter
130. Biering-Sørensen T, Christensen LM, Krieger DW, Mogelvang R, Jensen JS,
Højberg S et al. LA Emptying Fraction Improves Diagnosis of Paroxysmal AF After
Cryptogenic Ischemic Stroke: Results From the SURPRISE Study. JACC. Cardiovascular imaging. 2014 sep 7;7(9):962-963. Tilgængelig fra:
10.1016/j.jcmg.2014.02.003
Review
131. Ruwald MH, Bruun NE. Individualized cardiac resynchronization therapy: current status. Research Reports in Clinical Cardiology. 2014 nov 7;5:305-31. Tilgængelig fra: http://dx.doi.org/10.2147/RRCC.S50541
Kommentar/debat
132. Andersson C, Vasan RS. Lower is not always better?: Blood pressure treatment
targets revisited. Journal of the American College of Cardiology. 2014 aug
12;64(6):598-600. Tilgængelig fra: 10.1016/j.jacc.2014.04.066
133. Hlatky MA, Andersson C, Chang TI, Kazi D, Solomon MD, Go AS. Reply: Betablockers for angina: time to reassess the specific impact of drug therapy in coronary heart disease patients. Journal of the American College of Cardiology.
2014 dec 23;64(24):2712. Tilgængelig fra: 10.1016/j.jacc.2014.10.003
134. Jørgensen ME, Gislason GH, Andersson C. Time since stroke and risk of adverse outcomes after surgery--reply. J A M A: The Journal of the American Medical Association. 2014 nov 12;312(18):1930-1. Tilgængelig fra:
10.1001/jama.2014.13428
135. Lamberts M, Gislason GH, Olesen JB, Kristensen SL, Schjerning Olsen A-M,
Mikkelsen A et al. Reply: a persisting dilemma for triple antithrombotic therapy:
are we close to finding the correct answer?. Journal of the American College of
Cardiology. 2014 jul 15;64(2):231-2. Tilgængelig fra: 10.1016/j.jacc.2013.11.049
Ph.d.-afhandling
136. Carstensen HG. Comparison of regional and global longitudinal myocardial
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137. Jørgensen RM. Multipole Analysis of Heart Rate Variability in Patients with Acute Myocardial Infarction and Depressed Left Ventricular Systolic Function. 2014.
138. Karasoy D. Radiofrequency Ablation of Atrial Fibrillation: A Pharmacoepidemiological evaluation. 2014.
139. Kristensen SL. Inflammatory bowel disease and cardiovascular risk: Epidemiological Studies. Gentofte Universitetshospital, 2014. 54 s.
140. Selmer CLW. Thyroid Dysfunction and Cardiovascular Disease: Epidemiological
studies. Faculty of Health and Medical Sciences, University of Copenhagen,
2014. 46 s.
141. Weeke P. Psychiatric Pharmacotherapy and Out-of-Hospital Cardiac Arrest: Nationwide Danish Cohort Studies. 2014. 63 s.
Bidrag til bog/antologi
142. Gislason GH, Sørensen R. Triple Therapy: Risky But Sometimes Necessary. I
Avanzas P, Peter C, red., Pharmacological Treatment of Acute Coronary Syndromes. Springer. 2014. s. 185-212.
Case report
143. Pallisgaard JL, Gang U, Kanters JK, Hansen PR. Massive electrical storm at
disease onset in a patient with brugada syndrome. The American Journal of
Case Reports. 2014;15:559-61. Tilgængelig fra: 10.12659/AJCR.892314
19
Hud- og Allergiafd.
Hud- og Allergiafdelingen består af flere enheder.
Forskere, postdocs
Dermatologi med et dermato-venerologisk- ambula-
Johannes Waage, bioinformatik
torium/ behandlingsafsnit og alllergilaboratorium. Al-
Anna Hammerich Thysen, immunologi
lergologi med et allergiambulatorium og Laboratori-
Morten Arendt Rasmussen, kemometri
um for Medicinsk Allergologi. Endvidere Dansk Bør-
Tarun Veer Singh Ahluwalia, bioinformatik
neAstma Center, Videncenter for Allergi og Videncen-
Johan de Rool (Amsterdam Universitet), bioinformatik
ter for Frisører og Kosmetikere.
Ph.d.-studerende
Dermatologien og Videncenterne har følgende forsk-
Eskil Kreiner-Møller
ningstemaer: kontaktallergi (epidemiologi, risikofak-
Nadja Hawwa Vissing
torer, forebyggelse, genetik og immunologi), atopisk
Henrik Hallas
eksem, hudbarrieren og gen-miljø interaktioner og
Ann-Marie Malby Schoos
psoriasis (immunologi, lægemiddeludvikling, comor-
Astrid Sevelsted
biditet).
Helene Mygind Wolsk
Dansk BørneAstma Center forsker i astma, allergi og
Lambang Arianto
eksem på baggrund af to store fødselskohorte studier
Sunna Thorsteinsdottir
(risikofaktorer; herunder genetik og det humane
Jonathan Thorsen
mikrobiom, med henblik på bedre behandling og fo-
Anna Louise de Barros Damgaard
rebyggelse).
Allergologien herunder også Laboratorium for Medi-
Statistikere
cinsk Allergologi har forskningstemaerne: udredning,
Sune Birch, statistiker
mekanismer og behandling af IgE medieret allergi
(inhalationsallergi, fødevareallergi, lægemidler).
Administrative medarbejdere
Mette Damgaard Nielsen, Forskningsadministrator
Forskningstemaer
Marianne Mikkelsen, Administrativ Postdoc
 Kontaktallergi og eksem (privat og arbejdsbetinget)
Birgit Marie Nielsen, Økonomisk koordinator
Alma Jenny Pedersen, Regnskabsmedarbejder
 Psoriasis
Connie Albinski, Koordinerende sekretær
Søren Michael Westenholz, Datamanager
 Hudbarrieren
Dion Aagaard-Hansen, Datamanager
 Atopisk eksem
Brian Vegas Jørgensen, IT-manager
 IgE medieret allergi (inhalationsallergi, fødevareallergi, lægemidler)
Forskningsassistenter
Louise Nøttrup Monnerup
 Lægemiddel udvikling/allergi
Pernille Tegner Fjordholt
Lena Vind, Bioanalytiker
 Astma og allergi
Katrine Vegener, Laborant
 Vækst og fedme
Prægraduat forskningsstuderende
Ea Cecilie Jelding-Dannemand
Patrick René Gerhard Eriksen
COPSAC
Hans Bisgaard, professor, leder af Dansk BørneAstma
Center
Josefine Isabella Mainborg Andersen
Christina Figgé Christiansen
Iben Frier Ruge
Seniorforskere
Klaus Bønnelykke, Postdoc
Studentermedhjælpere
Bo Chawes, Postdoc
Anna Amalie Jepsen
Aga Smilde (Amsterdam Universitet), professor
Næstved klinikken (Næstved Sygehus)
Jakob Stokholm, Postdoc, seniorforsker
Tine-Marie Pedersen, Ph.d. studerende
20
Rebecca Vinding, Ph.d. studerende
Ph.d. studerende:
Hanne Lunn Nissen, Forskningsassistent
David Bregnbak, cand.med.
Tobias Sejersen, prægraduat forskningsårstud.
Jacob Kåre Ferløv Schwensen, cand.med.
Jonas Schmidt, cand scient.
Josefine Bandier, cand.med.
Klinik for allergi
Morten Schjørring Opstrup, cand.med. (sammen med
Lars K. Poulsen, professor, dr.med., forskningschef
Klink for Allergi)
Nina Glasser Hede, cand. scient.
Ph.d. studerende:
Thomas Dantoft, cand.polyt. (projekt om duft- og kemika-
Nanna Juel-Berg
lieoverfølsomhed)
Lau Fabricius Larsen
Ulrik Fischer Friis, cand. polyt.
Britta Poulsen
Seniorforskere:
Seniorforskere:
Annette Mollerup, cand. scient.san., ph.d.
Lars Blom
Berit Christina Carlsen, cand.med., ph.d.
Vanesa Esteban
Jacob P Thyssen, cand.med, ph.d., dr.med.
Lene Heise Garvey
Katrine Ross-Hansen, cand.scient., ph.d.
Bettina M. Jensen
Kåre Engkilde, cand. polyt., ph.d.
Maria Vølund Heisterberg, cand.med., ph.d.
Forskere:
Michael Dyrgård Lundov, cand.scient, ph.d.
Peter Rassing Andersen
Marianne Hald, cand.med, ph.d
Nikita Wu
Forskningsmedarbejdere:
Forskningsassistenter:
Pao Lung-Tsai, cand.mag., IT-specialist
Sara Fransson
Jens Tranholm Olesen, cand.polyt., IT-specialist
Ask Kvisselgard
Anne-Marie Topp, forskningssygeplejerske
Ida Skovgaard
Katia Winter Oreskov, stud.med.
Presa Mohammadzadeh, stud.med.
Prægraduat forskningsårstuderende
Victor Gjerding Bechmann
Teknisk assistance:
Malene Pravsgaard Christensen
Susanne Schweitz, Sekretær
Maria Gohr
Anette Toe Hansen
Videncenter for Frisører og Kosmetikere
Zina Kheder
Ulrik Fischer Friis, cand. polyt. ph.d., projektleder
Sanne Steensgaard
Ph.D. studerende
Majken Gabriel Hougaard, cand.med.
Forskningssygeplejerske:
Christina Monnerup Damving, klinisk projektkoordi-
Sanne Skovvang Steengaard, cand. scient.
nator
Teknisk og administrativt personale
Klinik for hudsygdomme
Iris Wintherstein, projektkoordinator
Lone Skov, professor, overlæge, dr.med., ph.d.,
Amir Hazrati, Data- og Quality manager
forskningsansvarlig overlæge
Scott Hansen, laborant
Shahin Aghazadeh, bioanalytiker
Adriana Sørensen, bioanalytiker
Gitte Harboe, forskningsansvarlig sygeplejerske
Katrine Vegener, laborant
Trine Blom Andersen, laborant-studerende
Seniorforskere:
Jacob P. Thyssen, MD dr. med. ph.d.
Videncenter for Allergi
Peter Jensen. MD Ph.d.
Jeanne Duus Johansen, Professor, dr.med., forsk-
Nannie Bangsgaard, MD ph.d.
ningschef
21
Ph.d. studerende:
10. Chawes BL, Govoni M, Piccinno A, Kreiner-Møller E, Vissing NH, Mortensen L et
al. A clinical pharmacology study of fixed vs. free combination of inhaled beclometasone dipropionate and formoterol fumarate dry powder inhalers in asthmatic adolescents. British journal of clinical pharmacology. 2014 nov;78(5):1169-71.
Tilgængelig fra: 10.1111/bcp.1242
Marianne B. Løvendorf, cand.scient.
Beatrice Dyring-Andersen, cand. med.
Mette Gyldenløve, cand. med.
11. Chawes BL, Bønnelykke K, Jensen PF, Schoos A-MM, Heickendorff L, Bisgaard H.
Cord blood 25(OH)-vitamin D deficiency and childhood asthma, allergy and eczema: the COPSAC2000 birth cohort study. P L o S One. 2014;9(6):e99856. Tilgængelig fra: 10.1371/journal.pone.0099856
Stine Simonsen, cand. med.
Kristiane Engebretsen, cand. med.
Ann Sophie Lønnborg, cand. med.
12. Chawes BL, Govoni M, Kreiner-Møller E, Vissing NH, Poorisrisak P, Mortensen L et
al. Systemic exposure to inhaled beclometasone/formoterol DPI is age and body
size dependent. Respiratory Medicine. 2014 aug;108(8):1108-16. Tilgængelig fra:
10.1016/j.rmed.2014.05.007
Forskningsassistenter:
Mie Mogensen, bioanalytiker
13. Damsgaard N, Hajari J, Heegaard S, Skov L. Månedens billede. Ugeskrift for læger
[online]. 2014 maj 12;176(10).
Anni Olsen, bioanalytiker
Nina B. Jørgensen, projektsygeplejerske
14. Dantoft TM, Elberling J, Brix S, Szecsi PB, Vesterhauge S, Skovbjerg S. An elevated pro-inflammatory cytokine profile in multiple chemical sensitivity. Psychoneuroendocrinology. 2014 feb;40:140-50. Tilgængelig fra:
10.1016/j.psyneuen.2013.11.012
Lina Rouyouf Khoury, stud. scient. san.
Prægraduat forskningsstudent:
15. Dyring Andersen B, Geisler C, Aggerbeck C, Lauritsen JPH, Gúdjonsdottir SD,
Skov L et al. Increased number and frequency of group 3 innate lymphoid cells in
non-lesional psoriatic skin. British Journal of Dermatology. 2014 mar;170(3):609616. Tilgængelig fra: 10.1111/bjd.12658
Raja Sikandar Aziz, stud med.
Professorer i 2014:
16. Elberling J, Bonde JPE, Vesterhauge S, Bang SH, Linneberg A, Zachariae C et al.
A new classification code is available in the Danish health-care classification system for patients with symptoms related to chemicals and scents. Ugeskrift for læger
[online]. 2014 maj 26;176(11):176.
Hans Bisgaard
Jeanne Duus Johansen
Lars K. Poulsen
Lone Skov
17. Elberling J, Arendt-Nielsen L. Transmission og modulation af kløe. Ugeskrift for
læger [online]. 2014 aug 4;176(32).
Publikationer 2014
18. Elberling J, Wulf HCO. treatment of Lentigo Maligna in Dark Skin with topical
Imiquimod Results in Dark Hyperpigmentation. International Journal of Dermatology. 2014;19-20.
1.
2.
Ahlehoff O, Skov L, Gislason G, Gniadecki R, Iversen L, Bryld LE et al. Cardiovascular outcomes and systemic anti-inflammatory drugs in patients with
severe psoriasis: 5-year follow-up of a Danish nationwide cohort. Journal of
the European Academy of Dermatology and Venereology : JEADV. 2014 okt
10. Tilgængelig fra: 10.1111/jdv.12768
19. Elmose C, Sverrild A, van der Sluis S, Kyvik KO, Backer V, Thomsen SF. Genetic
factors explain half of all variance in serum eosinophil cationic protein. Clinical and
experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 2014 dec 29;44(12):1525–1530. Tilgængelig fra: 10.1111/cea.12445
Andersen RMO, Zachariae C, Johansen JD. Aluminium allergy and granulomas induced by vaccinations for children. Ugeskrift for læger [online].
2014 mar 17;176(12A).
Bandier J, Johansen JD, Petersen LJ, Carlsen BC. Skin pH, atopic dermatitis, and filaggrin mutations. Dermatitis. 2014 maj 14;25(3):127-9.
Tilgængelig fra: 10.1097/DER.0000000000000045
20. Fage SW, Faurschou A, Thyssen JP. Copper hypersensitivity. Contact Dermatitis.
2014 okt;71(4):191-201. Tilgængelig fra: 10.1111/cod.12273
4.
Bisgaard H, Bønnelykke K, Stokholm J. Immune-mediated diseases and microbial exposure in early life. Clinical and experimental allergy : journal of
the British Society for Allergy and Clinical Immunology. 2014 apr;44(4):47581. Tilgængelig fra: 10.1111/cea.12291
22. Ferløv Schwensen J, Menné T, Veien NK, Funding AT, Avnstorp C, Osterballe M et
al. Occupational contact dermatitis in blue-collar workers: results from a multicentre
study from the Danish Contact Dermatitis Group (2003-2012). Contact Dermatitis.
2014 dec 18;71(6):348-355. Tilgængelig fra: 10.1111/cod.12277
5.
Bregnbak D, Thyssen JP, Zachariae C, Johansen JD. Characteristics of
chromium-allergic dermatitis patients prior to regulatory intervention for
chromium in leather: a questionnaire study. Contact Dermatitis. 2014
dec;71(6):338-347. Tilgængelig fra: 10.1111/cod.12291
23. Ferløv Schwensen J, Menné T, Andersen KE, Sommerlund M, Johansen JD.
Occupations at risk of developing contact allergy to isothiazolinones in Danish contact dermatitis patients: results from a Danish multicentre study (2009-2012). Contact Dermatitis. 2014 aug 21;71(5):295-302. Tilgængelig fra: 10.1111/cod.12286
6.
Bregnbak D, Friis UF, Zachariae C, Menné T, Johansen JD. Protein contact
dermatitis caused by worms and insects used to feed exotic birds. Contact
Dermatitis. 2014 jan;70(1):64-6. Tilgængelig fra: 10.1111/cod.12142
7.
Bruze M, Isaksson M, Gruvberger B, Andersen KE, Gonçalo M, Goossens A
et al. Patch testing with methylchloroisothiazolinone/methylisothiazolinone
200 ppm aq. detects significantly more contact allergy than 100 ppm. A multicentre study within the European Environmental and Contact Dermatitis
Research Group. Contact Dermatitis. 2014 jul;71(1):31-4. Tilgængelig fra:
10.1111/cod.12241
24. Ferløv Schwensen J, Menné T, Johansen JD. The combined diagnosis of allergic
and irritant contact dermatitis in a retrospective cohort of 1000 consecutive patients
with occupational contact dermatitis. Contact Dermatitis. 2014 aug 7;71(6):356–
363. Tilgængelig fra: 10.1111/cod.12288
3.
8.
9.
21. Ferløv Schwensen J, Bulut M, Nordholm-Carstensen A. Laparoscopy can be used
to diagnose peritoneal tuberculosis. Ugeskrift for læger [online]. 2014 sep
22;176(39).
25. Friis UF, Dahlin J, Bruze M, Menné T, Johansen JD. Hidden exposure to formaldehyde in a swab caused allergic contact dermatitis. Contact Dermatitis. 2014
apr;70(4):258-60. Tilgængelig fra: 10.1111/cod.12172
26. Friis UF, Menné T, Flyvholm M-A, Bonde JPE, Lepoittevin J-P, Le Coz CJ et al.
Isothiazolinones in commercial products at Danish workplaces. Contact Dermatitis.
2014 aug;71(2):65-74. Tilgængelig fra: 10.1111/cod.12235
Bråred Christensson J, Andersen KE, Bruze M, Johansen JD, Garcia-Bravo
B, Gimenez Arnau A et al. Positive patch test reactions to oxidized limonene: exposure and relevance. Contact Dermatitis. 2014 aug 7;71(5):264272. Tilgængelig fra: 10.1111/cod.12285
27. Friis UF, Menné T, Schwensen JF, Flyvholm M-A, Bonde JPE, Johansen JD.
Occupational irritant contact dermatitis diagnosed by analysis of contact irritants
and allergens in the work environment. Contact Dermatitis. 2014 okt 10;71(6):364370. Tilgængelig fra: 10.1111/cod.12290
Bønnelykke K, Sleiman P, Nielsen K, Kreiner-Møller E, Mercader JM, Belgrave D et al. A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations. Nature Genetics. 2014 jan;46(1):51-5. Tilgængelig fra: 10.1038/ng.283
28. Gallo J, Vaculova J, Goodman SB, Konttinen YT, Thyssen JP. Contributions of
human tissue analysis to understanding the mechanisms of loosening and osteolysis in total hip replacement. Acta Biomaterialia. 2014 jun;10(6):2354-66.
Tilgængelig fra: 10.1016/j.actbio.2014.02.003
29. Gether L, Thyssen JP, Avnstorp C. 'Allergyapp'--a novel app(lication) to detect contact
allergens in cosmetic products. Contact Dermatitis. 2014 dec;71(6):379-81. Tilgængelig
fra: 10.1111/cod.12309
22
30. Govoni M, Piccinno A, Lucci G, Poli G, Acerbi D, Baronio R et al. The systemic
exposure to inhaled beclometasone/formoterol pMDI with valved holding chamber is independent of age and body size. Pulmonary Pharmacology and Therapeutics. 2014 apr 16;30:102-109. Tilgængelig fra: 10.1016/j.pupt.2014.04.003
49. Høybye Bosteen M, Tritsaris K, Hansen AJ, Dissing S. IL-17A potentiates TNFαinduced secretion from human endothelial cells and alters barrier functions controlling
neutrophils rights of passage. Pflügers Archiv : European journal of physiology. 2014
maj;466(5):961-72. Tilgængelig fra: 10.1007/s00424-013-1354-5
31. Grunnet M, Christensen IJ, Lassen U, Jensen LH, Lydolph M, Lund IK et al.
Prognostic significance of circulating intact and cleaved forms of urokinase
plasminogen activator receptor in inoperable chemotherapy treated cholangiocarcinoma patients. Clinical biochemistry. 2014 feb 12;47(7-8):599-604.
Tilgængelig fra: 10.1016/j.clinbiochem.2014.01.030
50. Isaksson M, Andersen KE, Gonçalo M, Goossens A, Gruvberger B, Johansen JD et
al. Multicentre patch testing with methylisothiazolinone by the European Environmental and Contact Dermatitis Research Group. Contact Dermatitis. 2014
maj;70(5):317-20. Tilgængelig fra: 10.1111/cod.12220
51. Jakobsen SS, Lidén C, Søballe K, Johansen JD, Menné T, Lundgren L et al.
Failure of total hip implants: metals and metal release in 52 cases. Contact Dermatitis. 2014 jul 18;48(12). Tilgængelig fra: 10.1111/cod.12275
32. Grønhøj Larsen C, Gyldenløve M, Jensen DH, Therkildsen MH, Kiss K, Norrild B et al. Correlation between human papillomavirus and p16 overexpression in oropharyngeal tumours: a systematic review. B J C. 2014 mar
18;110(6):1587-94. Tilgængelig fra: 10.1038/bjc.2014.42
10.2340/00015555-1824
33. Grønhøj Larsen C, Brandt B. Traumatic oesophageal perforation due to
haematoma. International Journal of Surgery Case Reports.
2014;5(10):659-61. Tilgængelig fra: 10.1016/j.ijscr.2014.04.008
53. Jensen BM, Falkencrone S, Skov PS. Measuring histamine and cytokine release
from basophils and mast cells. Methods in molecular biology (Clifton, N.J.).
2014;1192:135-45. Tilgængelig fra: 10.1007/978-1-4939-1173-8_10
34. Gustafson K, Jakobsen SS, Lorenzen ND, Thyssen JP, Johansen JD, Bonefeld CM et al. Metal release and metal allergy after total hip replacement
with resurfacing versus conventional hybrid prosthesis. Acta Orthopaedica
(Print Edition). 2014 aug;85(4):348-54. Tilgængelig fra:
10.3109/17453674.2014.922730
54. Jensen BM, Frandsen P, Raaby EMN, Oluf Schiøtz P, Skov PS, Poulsen LK.
Molecular and stimulus-response profiles illustrate heterogeneity between peripheral and cord blood-derived human mast cells. Journal of Leukocyte Biology. 2014
feb 3;95(6):893-901. Tilgængelig fra: 10.1189/jlb.0712354
35. Gyldenløve M, Menné T, Thyssen JP. Eucalyptus contact allergy. Contact
Dermatitis. 2014 nov;71(5):303-4. Tilgængelig fra: 10.1111/cod.12268
55. Jensen P, Hamann D, Hamann CR, Jellesen MS, Jacob SE, Thyssen JP. Nickel
and cobalt release from children's toys purchased in Denmark and the United
States. Dermatitis. 2014 nov 11;25(6):356-65. Tilgængelig fra:
10.1097/DER.0000000000000084
36. Gyldenløve M, Tvede N, Larsen JL, Jacobsen S, Thyssen JP. Low prevalence of positive skin pathergy testing in Danish patients with Behçet's disease. Journal of the European Academy of Dermatology and Venereology :
JEADV. 2014;28(2):259-60. Tilgængelig fra: 10.1111/jdv.12189
56. Joensen UN, Jørgensen N, Meldgaard M, Frederiksen H, Andersson A-M, Menné T et
al. Associations of Filaggrin Gene Loss-of-Function Variants with Urinary Phthalate Metabolites and Testicular Function in Young Danish Men. Environmental Health Perspectives. 2014 apr;122(4):345-350. Tilgængelig fra: 10.1289/ehp.1306720
37. Gyldenløve M, Bjergager M. Månedens billede. Ugeskrift for læger [online].
2014 sep 1;176(36).
38. Gyldenløve M, Bjerager M. Månedens billede. Ugeskrift for Laeger.
2014;176(18):1689.
57. Khalid U, Ahlehoff O, Gislason GH, Kristensen SL, Skov L, Torp-Pedersen C et al.
Psoriasis and risk of heart failure: a nationwide cohort study. European Journal of Heart
Failure. 2014 jul;16(7):743-8. Tilgængelig fra: 10.1002/ejhf.113
39. Gyldenløve M, Jensen P, Linneberg A, Thyssen JP, Zachariae C, Hansen
PR et al. Psoriasis and the Framingham risk score in a Danish hospital cohort. International Journal of Dermatology. 2014 sep;53(9). Tilgængelig fra:
10.1111/ijd.12196
58. Kimber I, Basketter DA, Thyssen JP, Dearman RJ, McFadden JP. Chemical allergy in
humans: Fresh perspectives. Journal of Immunotoxicology. 2014 sep 25;11(3):203204. Tilgængelig fra: 10.3109/1547691X.2013.833661
40. Gyldenløve M, Rørvig S, Skov L, Hansen D. Severe hypercalcaemia,
nephrocalcinosis, and multiple paraffinomas caused by paraffin oil injections
in a young bodybuilder. Lancet. 2014 jun 14;383(9934):2098. Tilgængelig
fra: 10.1016/S0140-6736(14)60806-0
59. Kofoed K, Norrbom C, Forslund O, Møller C, Frøding LP, Pedersen AE et al. Low
Prevalence of Oral and Nasal Human Papillomavirus in Employees Performing
CO2-laser Evaporation of Genital Warts or Loop Electrode Excision Procedure of
Cervical Dysplasia. Acta Dermatovenereologica. 2015 jan 15;95(2):173-176.
Tilgængelig fra: 10.2340/00015555-1912
41. Gyldenløve M, Jensen P, Løvendorf MB, Zachariae C, Hansen PR, Skov L.
'Short-term treatment with methotrexate does not affect microvascular endothelial function in patients with psoriasis'. Journal of the European Academy of
Dermatology and Venereology : JEADV. 2014 feb 21;1-4. Tilgængelig fra:
10.1111/jdv.12385
60. Kofoed K, Sand C, Forslund O, Madsen K. Prevalence of Human Papillomavirus in
Anal and Oral Sites Among Patients with Genital Warts. Acta Dermatovenereologica. 2014 mar;94(2):207-211. Tilgængelig fra: 10.2340/00015555-1718
42. Hamann D, Yazar K, Hamann CR, Thyssen JP, Lidén C. p-Phenylenediamine
and other allergens in hair dye products in the United States: a consumer exposure study. Contact Dermatitis. 2014 apr;70(4):213-8. Tilgængelig fra:
10.1111/cod.12164
61. Kreiner-Møller E, Bisgaard H, Bønnelykke K. Prenatal and postnatal genetic
influence on lung function development. The Journal of allergy and clinical immunology. 2014 nov;134(5):1036-42.e15. Tilgængelig fra: 10.1016/j.jaci.2014.04.003
62. Kaae J, Szecsi PB, Meldgaard M, Espersen MLM, Stender S, Johansen JD et al.
Individuals with complete filaggrin deficiency may have an increased risk of squamous cell carcinoma. British Journal of Dermatology. 2014 jun;170(6):1380-1.
Tilgængelig fra: 10.1111/bjd.12911
43. Harder E, Andersen A-MN, Kamper-Jørgensen M, Skov L. No increased risk of
fetal death or prolonged time to pregnancy in women with psoriasis. The Journal of investigative dermatology. 2014 jun;134(6):1747-9. Tilgængelig fra:
10.1038/jid.2014.35
63. Larsen JM, Brix S, Thysen AH, Birch S, Rasmussen MA, Bisgaard H. Children with
asthma by school age display aberrant immune responses to pathogenic airway
bacteria as infants. The Journal of allergy and clinical immunology. 2014
apr;133(4):1008-1013.e4. Tilgængelig fra: 10.1016/j.jaci.2014.01.010
44. Heisterberg MV, Menné T, Johansen JD. Fragrance allergy and quality of life development and validation of a disease-specific quality of life instrument. Contact Dermatitis. 2014 feb;70(2):69-80. Tilgængelig fra: 10.1111/cod.12153
45. Heisterberg MV, Menné T, Johansen JD. Fragrance allergy and quality of life - a
case-control study. Contact Dermatitis. 2014 feb;70(2):81-9. Tilgængelig fra:
10.1111/cod.12128
64. Lindsted G, Larsen R, Krøigaard M, Garvey LH, Poulsen LK, Mosbech H et al.
Transfusion-associated anaphylaxis during anaesthesia and surgery--a retrospective study. Vox Sanguinis. 2014 aug;107(2):158-65. Tilgængelig fra:
10.1111/vox.12133
46. Hjortø S, Skov L, Lykke JA. Obstetric dermatoses. Ugeskrift for læger [online].
2014 sep 29;176(40).
65. Lundov MD, Kolarik B, Bossi R, Gunnarsen L, Johansen JD. Emission of isothiazolinones from water-based paints. Environmental Science and Technology. 2014
jun 17;48(12):6989-94. Tilgængelig fra: 10.1021/es500236m
47. Hougaard MG, Johansen JD, Linneberg A, Bandier J, Stender S, Carlsen BC et
al. Skin prick test reactivity to aeroallergens by filaggrin mutation status. European Academy of Dermatology and Venereology. Journal. 2014;28(14):238–
241. Tilgængelig fra: 10.1111/j.1468-3083.2012.04679.x
66. Lysdal SH, Mosbech H, Johansen JD, Søsted H. Asthma and respiratory symptoms
among hairdressers in Denmark: Results from a register based questionnaire
study. American Journal of Industrial Medicine. 2014 dec;57(12):1368-76.
Tilgængelig fra: 10.1002/ajim.22390
48. Husemoen LLN, Skaaby T, Martinussen T, Jørgensen T, Thuesen BH, Kistorp
C et al. Investigating the causal effect of vitamin D on serum adiponectin using
a mendelian randomization approach. European journal of clinical nutrition.
2014 feb;68:189-95. Tilgængelig fra: 10.1038/ejcn.2013.233
67. Lønnberg AS, Zachariae C, Skov L. Targeting of interleukin-17 in the treatment of
psoriasis. Clinical. Cosmetic and Investigational Dermatology. 2014;7:251-9.
Tilgængelig fra: 10.2147/CCID.S67534
23
68. Løvendorf MB, Zibert JR, Gyldenløve M, Røpke MA, Skov L. MicroRNA-223
and miR-143 are important systemic biomarkers for disease activity in psoriasis. Journal of Dermatological Science. 2014 aug;75(2):133-9.
Tilgængelig fra: 10.1016/j.jdermsci.2014.05.00
87. Schalock PC, Thyssen JP. Metal hypersensitivity reactions to implants: opinions and
practices of patch testing dermatologists. Dermatitis. 2014;24(6):313-20. Tilgængelig
fra: 10.1097/DER.0b013e3182a67d90
69. Malling H-J, Hansen KS, Garvey LH. Anafylaksi. Ugeskrift for læger [online].
2014 maj 26;176(22):2-6.
88. Schmidt JD, Johansen JD, Nielsen MM, Zimersson E, Svedman C, Bruze M et al.
Immune responses to hair dyes containing toluene-2,5-diamine. British Journal of Dermatology. 2014 feb;170(2):352-359. Tilgængelig fra: 10.1111/bjd.12676
70. Marstrand T, Ahler CB, Ralfkiaer U, Clemmensen A, Kopp KL, Sibbesen NA et
al. Validation of a diagnostic microRNA classifier in cutaneous T-cell lymphomas. Clinical Lymphoma, Myeloma & Leukemia. 2014 apr;55(4):957-958. Tilgængelig fra: 10.3109/10428194.2013.815352
89. Schwensen JF, Johansen JD, Veien NK, Funding AT, Avnstorp C, Osterballe M et al.
Occupational contact dermatitis in hairdressers: an analysis of patch test data from the
Danish contact dermatitis group, 2002-2011. Contact Dermatitis. 2014 apr;70(4):233-7.
Tilgængelig fra: 10.1111/cod.12176
71. Menné Bonefeld C, Nielsen MM, Gimenéz-Arnau E, Lang M, Vennegaard MT,
Geisler C et al. An immune response study of oakmoss absolute and its constituents atranol and chloroatranol. Contact Dermatitis. 2014 maj;70(5):282-90.
Tilgængelig fra: 10.1111/cod.12177
90. Simonsen AB, Deleuran M, Mortz CG, Johansen JD, Sommerlund M. Allergic
contact dermatitis in Danish children referred for patch testing - a nationwide multicentre study. Contact Dermatitis. 2014 feb;70(2):104-111. Tilgængelig fra:
10.1111/cod.12129
72. Michaelsen SH, Larsen CG, von Buchwald C. Human papillomavirus shows
highly variable prevalence in esophageal squamous cell carcinoma and no significant correlation to p16INK4a overexpression: a systematic review. Journal of
thoracic oncology : official publication of the International Association for the
Study of Lung Cancer. 2014 jun;9(6):865-71. Tilgængelig fra:
10.1097/JTO.0000000000000166
91. Skaaby T, Husemoen LLN, Jørgensen T, Johansen JD, Menné T, Szecsi PB et al.
Associations of Filaggrin Gene Loss-of-Function Variants and Human Papillomavirus-Related Cancer and Pre-Cancer in Danish Adults. P L o S One.
92. Skaaby T, Husemoen LLN, Thyssen JP, Meldgaard M, Thuesen BH, Pisinger C et
al. Filaggrin loss-of-function mutations and incident cancer: A population-based
study. British Journal of Dermatology. 2014 mar 14;171(6):1407-14. Tilgængelig
fra: 10.1111/bjd.12969
73. Mollerup A, Veien NK, Johansen JD. An analysis of gender differences in patients with hand eczema - everyday exposures, severity, and consequences.
Contact Dermatitis. 2014 jul;71(1):21-30. Tilgængelig fra: 10.1111/cod.12206
93. Sonnenschein-van der Voort AMM, Arends LR, de Jongste JC, Annesi-Maesano I,
Arshad SH, Barros H et al. Preterm birth, infant weight gain, and childhood asthma
risk: A meta-analysis of 147,000 European children. The Journal of allergy and clinical immunology. 2014 maj;133(5):1317-29. Tilgængelig fra:
10.1016/j.jaci.2013.12.1082
74. Mollerup A, Veien NK, Johansen JD. Effectiveness of the Healthy Skin Clinic - a
randomized clinical trial of nurse-led patient counselling in hand eczema. Contact Dermatitis. 2014 okt;71(4):202-14. Tilgængelig fra: 10.1111/cod.12243
75. Mortensen LJ, Kreiner-Møller E, Hakonarson H, Bønnelykke K, Bisgaard H. The
PCDH1-gene and asthma in early childhood. European Respiratory Journal.
2014 mar 1;43(3):792-800. Tilgængelig fra: 10.1183/09031936.00021613
94. Stokholm J, Schjørring S, Eskildsen CE, Pedersen L, Bischoff AL, Følsgaard N et
al. Antibiotic use during pregnancy alters the commensal vaginal microbiota. Clinical microbiology and infection : the official publication of the European Society of
Clinical Microbiology and Infectious Diseases. 2014 jul;20(7):629-635. Tilgængelig
fra: 10.1111/1469-0691.12411
76. Nielsen MM, Lovato P, MacLeod AS, Witherden DA, Skov L, Dyring-Andersen
B et al. IL-1β-dependent activation of dendritic epidermal T cells in contact hypersensitivity. Journal of immunology (Baltimore, Md. : 1950). 2014 apr
1;192(7):2975-83. Tilgængelig fra: 10.4049/jimmunol.130168
95. Stokholm J, Sevelsted A, Bønnelykke K, Bisgaard H. Maternal propensity for
infections and risk of childhood asthma: a registry-based cohort study. The Lancet
Respiratory Medicine. 2014 aug;2(8):631-7. Tilgængelig fra: 10.1016/S22132600(14)70152-3
77. Nilsson E, Chawes BLK, Bønnelykke K, Vindfeld S, Moore AC, Bisgaard H. Effect of delivery device on systemic exposure to inhaled fluticasone propionate in
children with asthma. British journal of clinical pharmacology. 2014
aug;78(2):435-7. Tilgængelig fra: 10.1111/bcp.1234
96. Svalgaard JD, Særmark C, Dall M, Buschard K, Johansen JD, Engkilde K. Systemic immunogenicity of para-Phenylenediamine and Diphenylcyclopropenone: two potent contact allergy-inducing haptens. Immunologic Research. 2014 jan;58(1):4050. Tilgængelig fra: 10.1007/s12026-013-8482-z
78. Olesen AB, Hædersdal M, Wulf HCO, Gniadecki R, Benfeldt EM. Voksende udfordringer vs. forbedrede behandlingsmuligheder inden for hudcancer. Ugeskrift
for Laeger. 2014 jun;176
97. Thomsen SF, Lei U. Månedens Billede: Neonatal lupus erythematosus. Ugeskrift
for læger [online]. 2014 mar 17;176(6).
79. Opstrup MS, Malling H-J, Krøigaard M, Mosbech H, Skov PS, Poulsen LK et al.
Standardized testing with chlorhexidine in perioperative allergy - a large singlecentre evaluation. Allergy. 2014 okt;69(10):1390-6. Tilgængelig fra:
10.1111/all.1246
98. Thuesen BH, Cerqueira C, Aadahl M, Ebstrup JF, Toft U, Thyssen JP et al. Cohort
Profile: The Health2006 cohort, Research Centre for Prevention and Health. International Journal of Epidemiology. 2014;43(2):568-575. Tilgængelig fra:
10.1093/ije/dyt009
80. Petersen AH, Johansen JD, Hald M. Hand eczema - prognosis and consequences: a 7 year follow-up study. British Journal of Dermatology. 2014 aug
25;70(4). Tilgængelig fra: 10.1111/bjd.13371
99. Thyssen JP, Jellesen MS, Møller P, Menné T, Johansen JD. Allergic chromium
dermatitis from wearing 'chromium-free' footwear. Contact Dermatitis. 2014
mar;70(3):185-7. Tilgængelig fra: 10.1111/cod.12189
81. Ralfkiaer U, Lindal L, Litman T, Gjerdrum L-M, Ahler CB, Gniadecki R et al. MicroRNA expression in early mycosis fungoides is distinctly different from atopic
dermatitis and advanced cutaneous T-cell lymphoma. Anticancer research.
2014 dec;34(12):7207-17.
100. Thyssen JP, Kezic S. Causes of epidermal filaggrin reduction and their role in the
pathogenesis of atopic dermatitis. The Journal of allergy and clinical immunology.
2014 okt;134(4):792-9. Tilgængelig fra: 10.1016/j.jaci.2014.06.014
82. Richardson C, Hamann CR, Hamann D, Thyssen JP. Mobile Phone Dermatitis
in Children and Adults: A Review of the Literature. Pediatric Asthma, Immunology, and Pulmonology. 2014 jun 1;27(2):60-69. Tilgængelig fra:
10.1089/ped.2013.0308
101. Thyssen JP, Bikle DD, Elias PM. Evidence That Loss-of-Function Filaggrin Gene
Mutations Evolved in Northern Europeans to Favor Intracutaneous Vitamin D3 Production. Evolutionary Biology. 2014 sep 1;41(3):388-396. Tilgængelig fra:
10.1007/s11692-014-9282-7
83. Ross-Hansen K, Ostergaard O, Tanassi JT, Thyssen JP, Johansen JD, Menné
T et al. Filaggrin Is a Predominant Member of the Denaturation-Resistant Nickel-Binding Proteome of Human Epidermis. The Journal of investigative dermatology. 2014 apr;134(4):1164-1166. Tilgængelig fra: 10.1038/jid.2013.445
102. Thyssen JP, Menné T, Johansen JD. Hexavalent chromium in leather is now
regulated in European Union member states to limit chromium allergy and dermatitis. Contact Dermatitis. 2014 jan;70(1):1-2. Tilgængelig fra: 10.1111/cod.12182
84. Ross-Hansen K, Johansen JD, Vølund A, Menné T, Thyssen JP. The nickel
dose-response relationship by filaggrin genotype (FLG). Contact Dermatitis.
2014 jul;71(1):49-53. Tilgængelig fra: 10.1111/cod.12228
103. Thyssen JP, McFadden JP, Kimber I. The multiple factors affecting the association
between atopic dermatitis and contact sensitization. Allergy. 2014 jan;69(1):28-36.
Tilgængelig fra: 10.1111/all.12358
85. Ryberg K, Agner T, Andersen KE, Bircher A, Diepgen T, Foti C et al. Patch testing with a textile dye mix - a multicentre study. Contact Dermatitis. 2014
okt;71(4):215-23. Tilgængelig fra: 10.1111/cod.12244
104. Thyssen JP, Vester L, Grønhøj Larsen C, Smidt K, Jakobsen P, Hansen SH et al.
The single-dose pharmacokinetics of Alitretinoin and its metabolites are not significantly altered in patients with cirrhosis. British Journal of Dermatology. 2014
feb;170(2):408-14. Tilgængelig fra: 10.1111/bjd.12546
86. Saetterstrøm B, Olsen J, Johansen JD. Cost-of-illness of patients with contact
dermatitis in Denmark. Contact Dermatitis. 2014 sep;71(3):154-61. Tilgængelig
fra: 10.1111/cod.12231
105. Thyssen JP, Laursen ASD, Husemoen LLN, Stender S, Szecsi PB, Menné T et al.
Variants in caspase-14 gene as risk factors for xerosis and atopic dermatitis. Journal of the European Academy of Dermatology and Venereology : JEADV. 2014 nov
30. Tilgængelig fra: 10.1111/jdv.12821
24
106. Tran MTD, Skovbjerg S, Arendt-Nielsen L, Bech P, Lunde MA, Elberling J.
Two of three patients with multiple chemical sensitivity had less symptoms
and secondary hyperalgesia aftert ranscranially applied pulsed electromagnetic fields. Scandinavian Journal of Pain. 2014;5:104-109.
107. van der Valk RJP, Duijts L, Timpson NJ, Salam MT, Standl M, Curtin JA et
al. Fraction of exhaled nitric oxide values in childhood are associated with
17q11.2-q12 and 17q12-q21 variants. The Journal of allergy and clinical
immunology. 2014 jul;134(1):46-55. Tilgængelig fra:
10.1016/j.jaci.2013.08.053
108. van Ree R, Hummelshøj L, Plantinga M, Poulsen LK, Swindle E. Allergic
sensitization: host-immune factors. Clinical and translational allergy. 2014
apr 15;4(1):12. Tilgængelig fra: 10.1186/2045-7022-4-12
109. Vennegaard MT, Dyring Andersen B, Skov L, Nielsen MM, Schmidt JD,
Bzorek M et al. Epicutaneous exposure to nickel induces nickel allergy in mice
via a MyD88-dependent and interleukin-1-dependent pathway. Contact Dermatitis. 2014 okt;71(4):224-32. Tilgængelig fra: 10.1111/cod.12270
Kommentar/debat
110. Bisgaard H, Stokholm J, Sevelsted A, Bønnelykke K. Maternal antibiotic use
and risk of asthma in offspring--Authors' reply. The Lancet Respiratory Medicine. 2014 okt;2(10):e17. Tilgængelig fra: 10.1016/S2213-2600(14)70221-8
111. Malling H-J, Witten M, Poulsen LK. Reply: To PMID 24035151. The Journal of
allergy and clinical immunology. 2014 mar;133(3):931-2. Tilgængelig fra:
10.1016/j.jaci.2013.11.037
Ph.d.-afhandling
112. Dyring Andersen B. Innate lymphoid cells and gamma delta T cells in inflammatory skin disease: A study of prevalence and phenotype in psoriasis and contact
allergy. 2014. 97 s.
113. Friis UF. Exposure assessment in occupational contact dermatitis. 1 udg. Videncenter for Allergi: Gentofte Universitetshospital, 2014. 105 s.
114. Kreiner-Møller E. A genetic approach to understanding asthma and lung function development. 2014.
115. Løvendorf MB. MicroRNAs as Biomarkers in Psoriasis. 2014. 78 s.
116. Mollerup A. Hand eczema Self Management and prognosis: Self Management
and prognosis. 2014. 113 s.
117. Thysen AH. Perinatal Environmental Effects on the Neonatal Immune System.
2014. 118 s.
118. Tran MTD. Central sensitization in multiple chemical sensitivity: Quantitative
sensory testing an therapeutic studies. 2014. 122 s.
119. Vissing NH. Neonatal Bacterial Colonization Predispose to Lower Respiratory
Infections in Early Childhood. 2014.
Konferenceabstrakt til konference
120. Jensen BM, Gohr M, Poulsen LK. Expression of the Transcription Factor E4BP4
in Human Basophils. 2014.
25
Klinisk Biokemisk afd.
Forskningstemaer
 Tilstedeværelsen af transfedtsyrer i populære føde-
4.
Baronaite R, Engelhart M, Mørk Hansen T, Thamsborg G, Slott Jensen H,
Stender S et al. A comparison of anti-nuclear antibody quantification using automated enzyme immunoassays and immunofluorescence assays. Autoimmune
Diseases. 2014;2014:534759. Tilgængelig fra: 10.1155/2014/534759
5.
Benn M. Statinbehandling og udvikling af diabetes mellitus. Ugeskrift for Laeger.2014 feb 3;176(3):218.
6.
Bladbjerg E-M, Larsen TM, Due A, Jespersen J, Stender S, Astrup A. Postprandial coagulation activation in overweight individuals after weight loss: acute and
long-term effects of a high-monounsaturated fat diet and a low-fat diet. Thrombosis Research. 2014 mar;133(3):327-33. Tilgængelig fra:
10.1016/j.thromres.2013.12.010
7.
Damsgaard CT, Eidner MB, Stark KD, Hjorth MF, Sjödin A, Andersen MR et al.
Eicosapentaenoic acid and docosahexaenoic acid in whole blood are differentially and sex-specifically associated with cardiometabolic risk markers in 8-11-yearold danish children. P L o S One. 2014;9(10):e109368. Tilgængelig fra:
10.1371/journal.pone.0109368
8.
Damsgaard CT, Dalskov S-M, Laursen R, Ritz C, Hjorth MF, Lauritzen L et al.
Provision of healthy school meals does not affect the metabolic syndrome score
in 8-11-year-old children, but reduces cardiometabolic risk markers despite increasing waist circumference. The British journal of nutrition. 2014 dec
14;112(11):1826-36. Tilgængelig fra: 10.1017/S0007114514003043
9.
Dantoft TM, Elberling J, Brix S, Szecsi PB, Vesterhauge S, Skovbjerg S. An
elevated pro-inflammatory cytokine profile in multiple chemical sensitivity. Psychoneuroendocrinology. 2014 feb;40:140-50. Tilgængelig fra:
10.1016/j.psyneuen.2013.11.012
varer i Europa
 Virkningen af omega-3 fedt på ikke fastende forhøjet triglycerid i plasma
 Forekomsten og betydningen af det hudtættende
protein filaggrin
 Betydningen af den præanalytiske håndtering af
blodprøverør for svartiden og det endelige analyseresultat
 Passiv rygning hos gravide og barnets fødselsvægt
 Mendelsk randomisering og risiko for diabetes og
kardiovaskulær sygdom
 Kønshormoner, genetisk variation og risiko for kardiovaskulær sygdom
 Familiær hyperkolesterolæmi i den almindelige befolkning
 Implementeringsforskning vedr. eEKG og decentral
glukosemåling på Gentofte Hospital
10. Ebdrup BH, Knop FK, Madsen A, Mortensen HB, Søgaard B, Holst JJ et al.
Glucometabolic hormones and cardiovascular risk markers in antipsychotictreated patients. Journal of Clinical Psychiatry. 2014 sep;75(9):e899-905. Tilgængelig fra: 10.4088/JCP.13m08820
Steen Stender, ledende overlæge, dr.med.
Pal Szesci, overlæge, dr.med.
11. Frikke-Schmidt R, Tybjærg-Hansen A, Dyson G, Haase CL, Benn M, Nordestgaard
BG et al. Subgroups at high risk for ischaemic heart disease-identification and validation in 67 000 individuals from the general population. International Journal of Epidemiology. 2014 okt 30;1-12. Tilgængelig fra: 10.1093/ije/dyu215
Klinisk forskningslektor og
seniorforsker delestilling
Marianne Benn, overlæge, dr. med, ph.d
12. Geiker N, Myint KS, Heck P, Dhatariya K, Hørup Larsen SM, Andersen MR et al.
Intentional Weight Loss Improved Performance in Obese Ischaemic Heart Patient: A
Two Centre Intervention Trial. Jacobs journal of food and nutrition. 2014;1(1). 003.
Seniorforsker
Sarah Caroline Wiesenfeldt Maroutt
13. Holmegard HN, Nordestgaard BG, Schnohr P, Tybjaerg-Hansen A, Benn M. Endogenous sex hormones and risk of venous thromboembolism in women and men.
Journal of thrombosis and haemostasis : JTH. 2014;12(3):297-305. Tilgængelig fra:
10.1111/jth.12484
14. Hornnes N, Larsen K, Brink-Kjær T, Boysen G. Specific antismoking advice after
stroke. Danish Medical Journal. 2014 apr;61(4). A4816.
Haya Nicole Holmegard, farmaceut, ph.d
Malene Rohr Andersen, projektkoordinator, ph.d.
15. Hougaard MG, Johansen JD, Linneberg A, Bandier J, Stender S, Carlsen BC et al.
Skin prick test reactivity to aeroallergens by filaggrin mutation status. European
Academy of Dermatology and Venereology. Journal. 2014;28(14):238–241.
Tilgængelig fra: 10.1111/j.1468-3083.2012.04679.x
Anne Hedengran Nedergaard, stud. med.
16. Husemoen LLN, Skaaby T, Martinussen T, Jørgensen T, Thuesen BH, Kistorp C et
al. Investigating the causal effect of vitamin D on serum adiponectin using a mendelian randomization approach. European journal of clinical nutrition. 2014 feb;68:18995. Tilgængelig fra: 10.1038/ejcn.2013.233
Steen Stender, ledende overlæge, dr.med.
Publikationer 2014
1.
Effect of Weight Loss on the Cardiovascular Risk Profile of Obese Patients with Psoriasis. Acta Dermatovenereologica. 2014 feb 20;94(6):691-4. Tilgængelig fra:
10.2340/00015555-1824
Aller EEJG, Larsen TM, Holst C, Lindroos AK, Kafatos A, Pfeiffer A et al.
Weight loss maintenance in overweight subjects on ad libitum diets with
high or low protein content and glycemic index: the DIOGENES trial 12month results. International journal of obesity (2005). 2014 mar
28;38(12):1511-1517. Tilgængelig fra: 10.1038/ijo.2014.52
2.
Amin FM, Hougaard A, Schytz HW, Asghar MS, Lundholm E, Parvaiz AI et
al. Investigation of the pathophysiological mechanisms of migraine attacks
induced by pituitary adenylate cyclase-activating polypeptide-38. Brain : a
journal of neurology. 2014;137:779-94. Tilgængelig fra:
10.1093/brain/awt369
3.
Astrup A, Larsen ML, Stender S, Dyerberg J. Fedtstoffernes betydning for forebyggelse af hjerte-kar-sygdom i Danmark. Ugeskrift for læger [online]. 2014 maj
5;176(19).
18. Joensen UN, Jørgensen N, Meldgaard M, Frederiksen H, Andersson A-M, Menné T
et al. Associations of Filaggrin Gene Loss-of-Function Variants with Urinary
Phthalate Metabolites and Testicular Function in Young Danish Men. Environmental
Health Perspectives. 2014 apr;122(4):345-350. Tilgængelig fra:
10.1289/ehp.1306720
19. Kaae J, Szecsi PB, Meldgaard M, Espersen MLM, Stender S, Johansen JD et al.
Individuals with complete filaggrin deficiency may have an increased risk of squamous cell carcinoma. British Journal of Dermatology. 2014 jun;170(6):1380-1. Tilgængelig fra: 10.1111/bjd.12911
26
20. Marott SCW, Nielsen SF, Benn M, Nordestgaard BG. Antihypertensive treatment and risk of atrial fibrillation: a nationwide study. European Heart Journal.
2014;35(18):1205. Tilgængelig fra: 10.1093/eurheartj/eht507
21. Poulsen SK, Due A, Jordy AB, Kiens B, Stark KD, Stender S et al. Health effect
of the New Nordic Diet in adults with increased waist circumference: a 6-mo
randomized controlled trial. The American journal of clinical nutrition. 2014
jan;99(1):35-45. Tilgængelig fra: 10.3945/ajcn.113.069393
22. Sibilitz KL, Benn M, Nordestgaard BG. Creatinine, eGFR and association with
myocardial infarction, ischemic heart disease and early death in the general
population. Atherosclerosis. 2014 sep 3;237(1):67-75. Tilgængelig fra:
10.1016/j.atherosclerosis.2014.08.040
23. Skaaby T, Husemoen LLN, Jørgensen T, Johansen JD, Menné T, Szecsi PB et
al. Associations of Filaggrin Gene Loss-of-Function Variants and Human Papillomavirus-Related Cancer and Pre-Cancer in Danish Adults. P L o S One.
24. Skaaby T, Husemoen LLN, Thyssen JP, Meldgaard M, Thuesen BH, Pisinger C
et al. Filaggrin loss-of-function mutations and incident cancer: A populationbased study. British Journal of Dermatology. 2014 mar 14;171(6):1407-14.
Tilgængelig fra: 10.1111/bjd.12969
25. Stender S, Astrup A, Dyerberg J. Tracing artificial trans fat in popular foods in
Europe: a market basket investigation. B M J Open. 2014;4(5):e005218.
Tilgængelig fra: 10.1136/bmjopen-2014-005218
26. Szecsi PB, Andersen MR, Bjørngaard B, Hedengran KK, Stender S. Cancer antigen 125 after delivery in women with a normal pregnancy: a prospective cohort
study. Acta Obstetricia et Gynecologica Scandinavica. 2014 dec;93(12):1295301. Tilgængelig fra: 10.1111/aogs.12492
27. Thyssen JP, Laursen ASD, Husemoen LLN, Stender S, Szecsi PB, Menné T et
al. Variants in caspase-14 gene as risk factors for xerosis and atopic dermatitis.
Journal of the European Academy of Dermatology and Venereology : JEADV.
2014 nov 30. Tilgængelig fra: 10.1111/jdv.12821
28. Varbo A, Benn M, Nordestgaard BG. Remnant cholesterol as a cause of ischemic heart disease: Evidence, definition, measurement, atherogenicity, high
risk patients, and present and future treatment. Pharmacology & Therapeutics.
2014 mar;141(3):358-67. Tilgængelig fra: 10.1016/j.pharmthera.2013.11.008
Kommentar/debat
29.
Brøndum-Jacobsen P, Nordestgaard BG, Nielsen SF, Benn M. Authors' Response to: Skin cancer as a marker of sun exposure-a case of serious immortality bias. International Journal of Epidemiology. 2014 jun;43(3):972-3.
Tilgængelig fra: 10.1093/ije/dyu102
30.
Brøndum-Jacobsen P, Nordestgaard BG, Nielsen SF, Benn M. Authors' response to: skin cancer as a marker of sun exposure. International Journal of
Epidemiology. 2014 dec;43(6):1992-3. Tilgængelig fra: 10.1093/ije/dyu211
31.
Varbo A, Benn M, Tybjærg-Hansen A, Nordestgaard BG. Reply to letters regarding article, "Elevated remnant cholesterol causes both low-grade inflammation and ischemic heart disease, whereas elevated low-density lipoprotein cholesterol causes ischemic heart disease without inflammation". Circulation (Baltimore). 2014 jun 17;129(24):e656. Tilgængelig fra:
Konferenceabstrakt i tidsskrift
32.
Ebdrup BH, Knop FK, Madsen A, Mortensen HB, Søgaard B, Holst JJ et al.
Glucometabolic Hormones and Cardiovascular Risk Markers in AntipsychoticTreated Patients. Schizophrenia Research. 2014 apr;153(Suppl. 1):90.
27
Lungemedicinsk afd.
På Lungemedicinsk afdeling er der omfattende forsk-
ning
Ingelise Trosborg, sygeplejerske, MVO
indenfor
screening
for
lungecancer,
CT-
kvantitering af emfysem, alfa1-antitrypsin mangel og
rygeafvænning. Afdelingens forskning indenfor disse
Publikationer 2014
områder på højt internationalt niveau. Der foregår
1.
Armbruster K, Naqibullah M, Clementsen PF. Pleuracentese. Ugeskrift for læger
[online]. 2014 maj 19;176(21).
2.
Ashraf H, Saghir Z, Dirksen A, Pedersen JH, Thomsen LH, Døssing M et al.
Smoking habits in the randomised Danish Lung Cancer Screening Trial with lowdose CT: final results after a 5-year screening programme. Thorax. 2014
jun;69(6):574-9. Tilgængelig fra: 10.1136/thoraxjnl-2013-203849
3.
Bendixen HJ, Wæhrens EE, Wilcke JT, Sørensen LV. Self-reported quality of
ADL task performance among patients with COPD exacerbations. Scandinavian
Journal of Occupational Therapy. 2014 jul;21(4):313-20. Tilgængelig fra:
10.3109/11038128.2014.899621
4.
Blauenfeldt T, Heyckendorf J, Graff Jensen S, Lange C, Drabe C, Hermansen TS
et al. Development of a One-Step Probe Based Molecular Assay for Rapid Immunodiagnosis of Infection with M. tuberculosis Using Dried Blood Spots. P L o S
One. 2014 sep 3;9(9):e105628. Tilgængelig fra: 10.1371/journal.pone.0105628
5.
Brodersen J, Dirksen A, Pedersen JH. Screening for lung cancer with low-dose
computed tomography. Annals of internal medicine. 2014 feb 4;160(3):212.
Tilgængelig fra: 10.7326/L14-5003-2
6.
Clementsen PF, Skov BG, Vilmann P, Krasnik M. Endobronchial ultrasoundguided biopsy performed under optimal conditions in patients with known or suspected lung cancer may render mediastinoscopy unnecessary. Journal of Bronchology & Interventional Pulmonology. 2014 jan;21(1):21-5. Tilgængelig fra:
10.1097/LBR.0000000000000028
7.
Colella S, Vilmann P, Konge L, Clementsen PF. Endoscopic ultrasound in the
diagnosis and staging of lung cancer. Endoscopic ultrasound. 2014 okt;3(4):20512. Tilgængelig fra: 10.4103/2303-9027.144510
8.
Gottlieb M, Clementsen PF, Håkansson K, Petersen RH, Konge L. Uventet fund
af endobronkial lungetumor ved bronkoskopi hos en storryger. Ugeskrift for læger
[online]. 2014 nov 3;176(45):V05140262.
9.
Jennum P, Tønnesen P. Obstruktiv søvnapnø-syndrom. Ugeskrift for læger
[online]. 2014 maj 26;176(11).
endvidere forskning i udredning af lungekræft (inklusiv screening med lav-dosis CT-scanning med særlig
bevilling fra Finansloven). Afdelingen har det ordinære
professorat i medicinske lungesygdomme for Københavns Universitet og endvidere en klinisk lektor.
Forskningstemaer
 Rygeafvænning
 Udredning af patienter mistænkt for lungecancer
 Screening af rygere for lungecancer
 NIV ved KOL og obstruktiv søvnapnø
 Billeddiagnostik ved KOL
 Interstitielle lungesygdomme
 Astma
 Tuberkulose
 Behandling af alfa1-antitrypsin mangel
Professorer
Asger Dirksen, overlæge, dr.med.
Jørgen Vestbo, dr.med.
Postdoc
10. Konradsen H, Lillebaek T, Wilcke JTR, Lomborg K. Being publicly diagnosed: A
grounded theory study of Danish patients with tuberculosis. International Journal
of Qualitative Studies on Health and Well-Being. 2014;9:1-8.
Torgny Wilcke, overlæge, ph.d.
11. Konradsen H, Trosborg I, Christensen L, Pedersen PU. Evaluation of interrater
Paul F. Clementsen, overlæge, dr.med.
12. Konradsen H, Trosborg I, Christensen L, Thomsen T, Pedersen PU. Who needs
Post.doc. delestilling
Hanne Konradsen, sygeplejerske, cand.cur., ph.d.
13. Larsen SS, Vilmann P, Krasnik K, Dirksen A, Clementsen P, Skov BG et al. A
comparison of endoscopic ultrasound guided biopsy and positron emission tomography with integrated computed tomography in lung cancer staging. Current
health sciences journal. 2014 jan;35(1):5-12.
Ph.d. studerende
Zaigham Saghir, cand.med.
Lone Skov Jensen, cand.cur.
14. Lock-Johansson S, Vestbo J, Sorensen G. Surfactant protein D, Club cell protein
16, Pulmonary and activation-regulated chemokine, C-reactive protein, and Fibrinogen biomarker variation in chronic obstructive lung disease. Respiratory research. 2014 nov 25;15(1):147. Tilgængelig fra: 10.1186/s12931-014-0147-5
Laura Hohwü Thomsen, cand.med.
Sidse Graff Jensen, cand.med.
Kasper Ankjærgaard, cand.med.
15. Lundbäck B, Bakke P, Ingebrigtsen T, Lange P, Lindberg A, Soriano JB et al.
Chronic obstructive pulmonary disease. Eur Respir Monograph. 2014;65:1-18.
Mathilde Marie Winkler Wille, cand.med.
16. Løkke A, Hilberg O, Tønnesen P, Ibsen R, Kjellberg J, Jennum P. Direct and
indirect economic and health consequences of COPD in Denmark: a national
register-based study: 1998-2010. B M J Open. 2014;4(1):e004069. Tilgængelig
fra: 10.1136/bmjopen-2013-004069
Ca. 10 forskningssygeplejersker og sekretærer
17. Noiesen E, Trosborg I, Bager L, Herning M, Lyngby C, Konradsen H. Constipation - prevalence and incidence among medical patients acutely admitted to hospital with a medical condition. Journal of Clinical Nursing. 2014 aug 1;23(1516):2295-2302. Tilgængelig fra: 10.1111/jocn.12511
Asger Dirksen, professor, overlæge, dr.med.
28
18. Petersen J, Wille MMW, Rakêt LL, Feragen A, Pedersen JH, Nielsen M et al.
Effect of inspiration on airway dimensions measured in maximal inspiration CT
images of subjects without airflow limitation. European Radiology. 2014
sep;24(9):2319-25. Tilgængelig fra: 10.1007/s00330-014-3261-3
19. Petersen J, Nielsen M, Lo P, Nordenmark LH, Pedersen JH, Wille MMW et al.
Optimal surface segmentation using flow lines to quantify airway abnormalities
in chronic obstructive pulmonary disease. Medical Image Analysis. 2014
apr;18(3):531-41. Tilgængelig fra: 10.1016/j.media.2014.02.004
20. Rasmussen JF, Siersma V, Pedersen JH, Heleno B, Saghir Z, Brodersen J.
Healthcare costs in the Danish randomised controlled lung cancer CTscreening trial: a registry study. Lung cancer (Amsterdam, Netherlands). 2014
mar;83(3):347-55. Tilgængelig fra: 10.1016/j.lungcan.2013.12.005
21. Ringbaek TJ, Seersholm N, Perch M, Iversen M, Lange P. Prognosis of patients
with alpha1-antitrypsine deficiency on long-term oxygen therapy. Respiratory
Medicine. 2014 aug;108(8):1189-94. Tilgængelig fra:
10.1016/j.rmed.2014.05.001
22. Saghir Z, Dirksen A, Ashraf H, Bach KS, Brodersen J, Clementsen PF et al.
Screening for lungecancer med lavdosis-CT - danske og udenlandske resultater. Ugeskrift for læger [online]. 2014 okt 13;176(42):V05140283.
23. Savran MM, Clementsen PF, Annema JT, Minddal V, Larsen KR, Park YS et al.
Development and validation of a theoretical test in endosonography for pulmonary diseases. Respiration; international review of thoracic diseases.
2014;88(1):67-73. Tilgængelig fra: 10.1159/000362884
24. Sommer MS, Trier K, Vibe-Petersen J, Missel M, Christensen M, Larsen KR et
al. Perioperative rehabilitation in operation for lung cancer (PROLUCA) - rationale and design. B M C Cancer. 2014;14. 404. Tilgængelig fra:
10.1186/1471-2407-14-404
25. Suzuki M, Makita H, Östling J, Thomsen LH, Konno S, Nagai K et al. Lower leptin/adiponectin ratio and risk of rapid lung function decline in chronic obstructive
pulmonary disease. Annals of the American Thoracic Society. 2014
dec;11(10):1511-9. Tilgængelig fra: 10.1513/AnnalsATS.201408-351OC
26. Thomsen LH, Dirksen A, Shaker SB, Skovgaard LT, Dahlbäck M, Pedersen JH.
Analysis of FEV1 decline in relatively healthy heavy smokers: implications of
expressing changes in FEV1 in relative terms. COPD. 2014 feb;11(1):96-104.
Tilgængelig fra: 10.3109/15412555.2013.830096
27. Tønnesen P. E-cigaretten: et middel til rygestop uden support?. Ugeskrift for
læger [online]. 2014 sep 1;176(36).
28. Vestbo J. Chronic bronchitis: so much more than just a smoker's cough. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease. 2014 jul;18(7):760.
Tilgængelig fra: 10.5588/ijtld.14.0357
29. Vestbo J, Celli B. Chronic obstructive pulmonary disease: different risk factors
and different natural histories?. American journal of respiratory and critical care
medicine. 2014 nov 1;190(9):968-70. Tilgængelig fra: 10.1164/rccm.2014091705ED
30. Wille MMW, Thomsen LH, Dirksen A, Petersen J, Pedersen JH, Shaker SB.
Emphysema progression is visually detectable in low-dose CT in continuous but
not in former smokers. European Radiology. 2014 nov;24(11):2692-9.
31. Willendrup F, Bodtger U, Colella S, Rasmussen D, Clementsen PF. Diagnostic
accuracy and safety of semirigid thoracoscopy in exudative pleural effusions in
Denmark. Journal of Bronchology & Interventional Pulmonology. 2014
jul;21(3):215-9. Tilgængelig fra: 10.1097/LBR.0000000000000088
Ph.d.-afhandling
32. Rasmussen T. Coronary Artery Calcification in Current and Former Smokers
Assessed with Multi-detector Computed Tomography (Ph.d.-afhandling): Relation to Lung Function and Prognostic Value in Lung Cancer Screening. København: Eget forlag Københavns University, 2014. 57 s.
29
Medicinsk afd. C
Forskningstemaer
 Validering af kliniske sygdomsmarkører og

outcome measures på individ-niveau indenfor
Sammenhæng mellemvestibulær dysfunktion og
søvnapnø
reumatologien

 Biokemiske markører og billeddiagnostiske
Intial ortostatisk hypotension hos patienter med
vestibulær dysfunktion
undersøgelser (MR, CT, ultralyd) til diagnosti-

Databaseforskning indenfor geriatri
cering, monitorering og prognosticering af in-

Sygeplejerske-telefonkonsultationer med reuma-
flammatoriske ryg- og ledsygdomme
tologiske patienter
 Kardiovaskulære risikofaktorer hos patienter
med reumatoid artrit (PET-CT mv.)
 Risiko for urinvejsinfektioner og værdi af
screening ved biologisk behandling af inflam-
Ole Rintek Madsen, overlæge, dr.med.
matorisk ledsygdom
Lene Dreyer, overlæge, ph.d.
 Prognostiske faktorer ved psoriasisgigt
 Databaseforskning indenfor sklerodermi, SLE,
Ph.d. studerende
artrit
Carrinna Hansen, klinisk udviklingssygeplejerske
 Sjældne bivirkninger ved behandling med biologisk medicin herunder cancer og demyelini-
serende sygdomme
Jan Pødenphant, overlæge, dr.med..
 Steroidinduceret binyrebarkinsuficiens
Merete Engelhart, overlæge, dr.med.
 Osteoporose og reumatopid artrit (FRAX)
Annette Hansen, specialeansvarlig overlæge
 Patient-tilfredshedsundersøgelser, studier i
Pia Nimann Kanegaard, overlæge
optimale infusionsforløb og rationel klinisk
Marianne Kirchhoff, overlæge ph.d.
kontrol i forbindelse med biologisk behandling
Kirsten Damgaard, led. overlæge, dr. med.
 Opsporing og intervention overfor faldpatien-
Susanne Juhl Pedersen, læge, ph.d
ter
Bente Glintborg, reservelæge ph.d.
 Validering af måleredskaber for vurdering af
Gunhild Bukh, afdelingssygeplejerske
funktion hos patienter med vestibulær dys-
Anne Villadsen, klinisk sygeplejespecialist
funktion
Anne-Marie Tetche Sweeney, sygeplejerske
 Rehabilitering af KOL indlagt med forværring i
Rikke Terp, klinisk sygeplejespecialist
KOL
Carsten Juhl, forsknings- og udviklingsfysioterapeut
 Effekten af træning til patienter med diabetes
Kasper Søndergaard, forsknings- og udviklingsfysio-
 Tværsektionelt ernæringsprojekt – geriatriske
terapeut
patienter i ernæringsmæssig risiko
Isabella Rogon, fysioterapeut
 Register forskning – risikofaktorer for apoplekse recidiv hos ambulante apopleksipatien-
Forskningsansvarlig overlæge:
ter
Ole Rintek Madsen, klinisk lektor, ph.d., dr.med.
 Træthed hos patienter med SLE og reumatoid
artrit
 ”Åbent ambulatorium” – patienter med ledde-
Rikke Terp Sørensen, klinisk sygeplejespecialist
gigt
 Anvendelsen af De Morton Mobility Index
(DEMMI) i det tværsektorielle forløb
Publikationer 2014
 Validering af fysioterapeutiske målemetoder til
1.
Agarwal D, Pineda S, Michailidou K, Herranz J, Pita G, Moreno LT et al. FGF
receptor genes and breast cancer susceptibility: results from the Breast Cancer
Association Consortium. B J C. 2014 feb 18;110(4):1088-100. Tilgængelig fra:
10.1038/bjc.2013.769
2.
Andersen TR, Schmidt JF, Nielsen JJ, Randers MB, Sundstrup E, Jakobsen MD
et al. Effect of football or strength training on functional ability and physical performance in untrained old men. Scandinavian journal of medicine & science in
sports. 2014 aug;24 Suppl 1:76-85. Tilgængelig fra: 10.1111/sms.12245
patienter med nedsat balance og svimmelhed
 Søvn – undersøgelse af indlagte patienters
søvnkvalitet og betydningen heraf – et forskningsprojekt på tværs af afdelinger
 Pårørende-deltagelse via Skype-samtaler
 Sammenhæng mellem aldersbetinget hørenedsættelse og vestbulær dysfunktion/balance
30
3.
Axelsen MB, Eshed I, Duer A, Møller JM, Pedersen SJ, Østergaard M. Wholebody MRI assessment of disease activity and structural damage in rheumatoid
arthritis: first step towards an MRI joint count. Rheumatology (Oxford, England).
2014 jan 3;845-53. Tilgængelig fra: 10.1093/rheumatology/ket425
4.
Baronaite R, Engelhart M, Mørk Hansen T, Thamsborg G, Slott Jensen H,
Stender S et al. A comparison of anti-nuclear antibody quantification using automated enzyme immunoassays and immunofluorescence assays. Autoimmune
Diseases. 2014;2014:534759. Tilgængelig fra: 10.1155/2014/534759
5.
6.
7.
8.
9.
10.
11.
12.
13.
Bernatsky S, Ramsey-Goldman R, Joseph L, Boivin J-F, Costenbader KH,
Urowitz MB et al. Lymphoma risk in systemic lupus: effects of disease activity
versus treatment. Annals of the Rheumatic Diseases. 2014;73:138-142.
Tilgængelig fra: 10.1136/annrheumdis-2012-202099
Bukh G, Tommerup AMM, Madsen OR. Impact of healthcare design on patients'
perception of a rheumatology outpatient infusion room: an interventional pilot
study. Clinical rheumatology. 2014 apr 8. Tilgængelig fra: 10.1007/s10067-0142592-4
Cordtz R, Mellemkjær L, Glintborg B, Hetland ML, Dreyer L. Malignant progression of precancerous lesions of the uterine cervix following DMARD therapy in
female arthritis patients. Arthritis & Rheumatology. 2014;66(Suppl. 11):S374-5.
Egsmose EL, Birkvig M, Buhl T, Madsen OR. FRAX fracture risk in women with
a recent fracture of the distal forearm: agreement between assessments with
and without bone mineral density and impact of measurement side in the individual patient. Clinical rheumatology. 2014 maj 14. Tilgængelig fra:
10.1007/s10067-014-2640-0
Glintborg B, Gudbjornsson B, Steen Krogh N, Omerovic E, Manilo N, HollandFischer M et al. Impact of different infliximab dose regimens on treatment response and drug survival in 462 patients with psoriatic arthritis: results from the
nationwide registries DANBIO and ICEBIO. Rheumatology (Oxford, England).
2014 nov;53(11):2100-9. Tilgængelig fra: 10.1093/rheumatology/keu252
Hansen C, Konradsen H, Abrahamsen B, Pedersen B. Women’s experiences of
their osteoporosis diagnosis at the time of diagnosis and six months later: a
Phenomenological-hermeneutic Study. International Journal of Qualitative Studies on Health and Well-Being. 2014;22438. Tilgængelig fra:
doi.org/10.3402/qhw.v9.22438
19.
Poggenborg RP, Wiell C, Bøyesen P, Boonen A, Bird P, Pedersen SJ et al. No
overall damage progression despite persistent inflammation in adalimumab-treated
psoriatic arthritis patients: results from an investigator-initiated 48-week comparative magnetic resonance imaging, computed tomography and radiography trial.
Rheumatology (Oxford, England). 2014 apr;53(4):746-756. Tilgængelig fra:
10.1093/rheumatology/ket426
20.
Poggenborg RP, Bird P, Boonen A, Wiell C, Pedersen SJ, Sørensen IJ et al.
Pattern of bone erosion and bone proliferation in psoriatic arthritis hands: a highresolution computed tomography and radiography follow-up study during adalimumab therapy. Scandinavian Journal of Rheumatology. 2014;43(3):202-8.
Tilgængelig fra: 10.3109/03009742.2013.835865
21.
Poulsen MH, Frost M, Abrahamsen B, Brixen K, Walter S. Osteoporosis and
prostate cancer: a cross-sectional study of Danish men with prostate cancer before
androgen deprivation therapy. Scandinavian Journal of Urology and Nephrology.
2014 feb 19;48(4):350-355. Tilgængelig fra: 10.3109/21681805.2014.884160
22.
Theibich A, Dreyer L, Magyari M, Locht H. Demyelinizing neurological disease after
treatment with tumor necrosis factor alpha-inhibiting agents in a rheumatological
outpatient clinic: description of six cases. Clinical rheumatology. 2014
maj;33(5):719-723. Tilgængelig fra: 10.1007/s10067-013-2419-8
23.
Villadsen AØ, Toft M. Lupuspatienter forsker i egen sygdom. ReumaDebat. 2014
apr 1;April 2014:12-13.
24.
Ørnbjerg LM, Østergaard M, Bøyesen P, Krogh NS, Thormann A, Tarp U et al.
Which factors influence radiographic progression during treatment with tumor necrosis factor inhibitors in clinical practice?: Results from 930 patients with rheumatoid arthritis in the nationwide Danish DANBIO registry. Journal of Rheumatology.
2014 dec;41(12):2352-60. Tilgængelig fra: 10.3899/jrheum.131299
25.
Østergaard M, Jacobsson LTH, Schaufelberger C, Hansen MS, Bijlsma JWJ,
Dudek A et al. MRI assessment of early response to certolizumab pegol in rheumatoid arthritis: a randomised, double-blind, placebo-controlled phase IIIb study applying MRI at weeks 0, 1, 2, 4, 8 and 16. Annals of the Rheumatic Diseases. 2014 dec
15. Tilgængelig fra: 10.1136/annrheumdis-2014-206359
Huynh TK, Ostergaard A, Egsmose C, Madsen OR. Preferences of patients and
health professionals for route and frequency of administration of biologic agents
in the treatment of rheumatoid arthritis. Patient Preference and Adherence.
2014;8:93-9. Tilgængelig fra: 10.2147/PPA.S55156
Højgaard P, Glintborg B, Hetland ML, Hansen TH, Nilsson C, Lage-Hansen PR
et al. Association between tobacco smoking and response to tumor necrosis
factor alpha inhibitor treatment in psoriatic arthritis: Results from the DANBIO
registry. Annals of the Rheumatic Diseases. 2014;73(Suppl. 2):743.
Jensen TW, Hansen MS, Hørslev-Petersen K, Hyldstrup L, Abrahamsen B,
Langdahl BL et al. Periarticular and generalised bone loss in patients with early
rheumatoid arthritis: influence of alendronate and intra-articular glucocorticoid
treatment. Post hoc analyses from the CIMESTRA trial. Annals of the Rheumatic Diseases. 2014 maj 9;73(6):1123-1129. Tilgængelig fra:
10.1136/annrheumdis-2012-203171
26.
Askling J, Dreyer L, Hetland ML, Jacobsson L, Kristensen L-E, Glintborg B. Cancer
incidence in TNF inhibitor treated patients with axial spondyloarthritis and psoriatic
arthritis - a study from the ARTIS and Danbio registers. Arthritis & Rheumatology.
2014;66(Suppl. 11):S377-8.
27.
Bliddal H, Eriksen SA, Christensen R, Lorenzen T, Hansen MS, Østergaard M et al.
Adherence to methotrexate in rheumatoid arthritis treated by practice vs. hospital
based rheumatologists: A Danish nationwide cohort study. Annals of the Rheumatic
Diseases. 2014;73(Suppl. 2):448-9.
28.
Keller A, Sørensen IJ, Østergaard M, Madsen OR, Asmussen KH, Møller JM et al.
Does TNFα-inhibition influence the progression of degenerative changes in the
lumbar spine in patients with axial spondylarthritis (ax-SpA)?. Annals of the Rheumatic Diseases. 2014;73(Suppl. 2):297.
29.
Krabbe S, Bolce RJ, Brahe CH, Møller Døhn U, Wu G, Ejbjerg B et al. Validation of
a multi-biomarker disease activity score in rheumatoid arthritis in relation to imaging
inflammation and damage. Annals of the Rheumatic Diseases. 2014;73(Suppl.
2):396.
14.
Juhl CB, Christensen R, Roos EM, Zhang W, Lund H. Impact of exercise type
and dose on pain and disability in knee osteoarthritis: a systematic review and
meta-regression analysis of randomized controlled trials. Arthritis & Rheumatism. 2014 mar;66(3):622-36. Tilgængelig fra: 10.1002/art.38290
30.
Mercer L, Mariette X, Dixon W, Baecklund E, Hellgren K, Dreyer L et al. First results
of a european registries collaborative project to compare the spectrum of lymphomas between different exposure groups in rheumatoid arthritis. Arthritis & Rheumatology. 2014;66(Suppl. 11):S806-7.
15.
Jørgensen TSH, Hansen AH, Sahlberg M, Gislason GH, Torp-Pedersen C, Andersson C et al. Falls and comorbidity: The pathway to fractures. Scandinavian
journal of public health. 2014 maj;42(3):287-94. Tilgængelig fra:
10.1177/1403494813516831
31.
Mercer L, Askling J, Raaschou P, Dixon W, Dreyer L, Hetland ML et al. No increased risk of developing a first invasive melanoma in rheumatoid arthritis patients
treated with biologics: Results of a collaborative project of 11 european biologics
registers. Arthritis & Rheumatology. 2014;66(Suppl. 11):S807-8.
16.
Krabbe S, Eshed I, Pedersen SJ, Bøyesen P, Møller JM, Therkildsen F et al.
Bone marrow oedema assessment by magnetic resonance imaging in rheumatoid arthritis wrist and metacarpophalangeal joints: the importance of field
strength, coil type and image resolution. Rheumatology (Oxford, England). 2014
aug;53(8):1446-51. Tilgængelig fra: 10.1093/rheumatology/keu029
32.
Møller JM, Sørensen IJ, Thomsen HS, Østergaard M, Madsen OR, Pedersen SJ.
Reproducibility of magnetic resonance diffusion weighted imaging in axial spondyloarthritis patients and healthy subjects. Annals of the Rheumatic Diseases.
2014;73(Suppl. 2):1122.
17.
Lindhardsen J, Gislason GH, Jacobsen S, Ahlehoff O, Olsen A-MS, Madsen OR
et al. Non-steroidal anti-inflammatory drugs and risk of cardiovascular disease
in patients with rheumatoid arthritis: a nationwide cohort study. Annals of the
Rheumatic Diseases. 2014;73:1515-1521 . Tilgængelig fra:
10.1136/annrheumdis-2012-203137
33.
Møller JM, Sørensen IJ, Østergaard M, Thomsen H, Madsen OR, Pedersen SJ.
Reproducibility of Magnetic resonance imaging diffusion weighted imaging in axial
spondyloarthritis patients and healthy subjects. Arthritis & Rheumatology.
2014;66(Suppl. 11):S523.
18.
Noiesen E, Trosborg I, Bager L, Herning M, Lyngby C, Konradsen H. Constipation - prevalence and incidence among medical patients acutely admitted to
hospital with a medical condition. Journal of Clinical Nursing. 2014 aug 1;23(1516):2295-2302. Tilgængelig fra: 10.1111/jocn.12511
34.
Poggenborg RP, Pedersen SJ, Eshed I, Sørensen IJ, Madsen OR, Møller JM et al.
Whole-body and conventional magnetic resonance imaging for assessing inflammation and structural damage in psoriatic arthritis and axial spondyloarthritis.
Scandinavian Journal of Rheumatology. 2014;43(Suppl. 127):74-5.
31
35.
Ørnbjerg LM, Østergaard M, Bøyesen P, Jensen T, Thormann A, Tarp U et al.
Impact of tumor necrosis factor inhibitor treatment on hand bone loss in rheumatoid arthritis patients treated in clinical practice: results from the nationwide
Danish DANBIO registry. Scandinavian Journal of Rheumatology.
2014;43(Suppl. 127):27-8.
36.
Østergaard M, Axelsen MB, Jacobsson LTH, Schaufelberger C, Hansen MS,
Bijlsma JWJ et al. Dynamic magnetic resonance imaging in the assessment of
the response to Certolizumab Pegol in rheumatoid arthritis patients: results from
a phase IIIb randomized study. Arthritis & Rheumatology. 2014;66(Suppl.
11):S518-19.
32
Medicinsk afd. F
Afdelingens specialer er medicinsk endokrinologi,
gastroenterologi-hepatologi og intern medicin. Til
afdelingen er knyttet Medicinsk forskningslaboratorium, som varetager såvel basal som klinisk
forskning i afdelingens specialer samt Center for
Diabetesforskning. I tillæg til den kliniske og
laboratoriemæssige forskning har afdelingen et
forskningsmiljø indenfor epidemiologi, klinisk
farmakologi og farmakoepidemiologi knyttet til
specialerne. Forskningen indgår i højt estimerede
internationale og nationale forskningsnetværk.
Forskningstemaer

Jonatan Ising Bagger, læge

Kristian Hallundbæk Mikkelsen, læge

Mikkel Christensen, læge

Morten Hansen, læge

Nicolai Alexander Rhee, læge

Signe Foghsgaard, læge

Signe Harring Østoft, læge

Tina Jorsal, læge

Ulrich Rohde, læge

Pelle Lau Ishøj (Psykiatrisk, Glostrup)

Thomas Idorn (Nefrologisk, Rigshospitalet)

Morten Buus Jørgensen (Rigshospitalet)
Center for Diabetesforskning ledes af professor,

Julie Rask (Psykiatrisk, Rigshospitalet)
specialeansvarlig overlæge, dr. med. Tina Vilsbøll og

Jacob Sivertsen, læge (Hjertemedicinsk)
lektor, forskningsansvarlig overlæge, ph.d. Filip Krag

Peter Godsk Jørgensen, læge (Hjertemedicinsk)
Knop.

Mette Gyldenløve (Hud- og allergiafd.)
Hidtidige forskningsresultater har ændret forståelsen

Thomas F. Dejgaard, læge (clinical supervisor)
af diabetes og peger i retning af, at tarmen og tarmhormoner udgør vigtige mål for uopdagede sygdoms-
Senior forskere
mekanismer og dermed muligheder for nye behand-

Jørgen Rungby, professor, overlæge, dr.med.
lingsmetoder.

Brynjulf Mortensen, ph.d., post.doc.
Enheden repræsenterer et innovativt forskningsmiljø

Heidi Storgaard, overlæge, ph.d.
med et omfattende netværk af kliniske forskere, hvor

Michael Røder, overlæge, dr. med.
der udføres patientnær forskning af høj kvalitet -

Thomas Peter Almdal, overlæge, dr. med.
spændene fra basal fysiologi over human

Louise Vedtofte, ph.d., post doc
patofysiologi til randomiserede kliniske
undersøgelser.
Forskningsstipendiater
Det overordnede mål er, at identificere og

Emilie Bahne, stud.med.
videreudvikle antidiabetiske behandlingsmodaliteter

Emilie Skytte Andersen, stud.med.
baseret på de beskrevne mekanismer og nye

Magnus Grøndahl, stud.med
behandlingsmetoder.

Malthe Palm Suppli, stud.med.

Pernille Mensberg, stud.scient.
Center for Diabetesforskning blev som et af de få i

Signe Nyby, stud.scient.
Regionen tildelt Global Excellence prisen i 2014.

Simon Vedfald, stud. med.
Seniorforskere delestilling
Thomas Almdal, overlæge, dr.med.
Gastroenterologisk forskning
 Klinisk og epidemiologisk forskning i cøliaki
Jørgen
og malabsorption


Rungby,
adj.
professor,
overlæge,
dr.med.
Grundvidenskabelig og translatorisk
forskning i strukturel cellebiologi og glatmu-
skelfunktion
Filip Krag Knop., overlæge, ph.d.
Klinisk og epidemiologisk forskning i
inflammatorisk tarmsygdom
Eline Noiesen, sygeplejerske, cand.mag.
Ph.d. studerende

Anders Ellekær Junker, læge

Andreas Brønden, læge

Asger Lund, læge

David Peick Sonne, læge
33
Publikationer 2014
1.
2.
3.
4.
5.
6.
17. Chalmer T, Almdal TP, Vilsbøll T, Knop FK. Adverse drug reactions associated
with the use of liraglutide in patients with type 2 diabetes - focus on pancreatitis and pancreas cancer. Expert Opinion on Drug Safety. 2014 nov 3;1-10.
Tilgængelig fra: 10.1517/14740338.2015.975205
Abrahamsen B, Grove E, Vestergaard P. Nationwide registry-based analysis
of cardiovascular risk factors and adverse outcomes in patients treated with
strontium ranelate. Osteoporosis international : a journal established as result
of cooperation between the European Foundation for Osteoporosis and the
National Osteoporosis Foundation of the USA. 2014 feb;25(2):757-62. Tilgængelig fra: 10.1007/s00198-013-2469-4
18. Christensen M, Miossec P, Larsen BD, Werner U, Knop FK. The design and
discovery of lixisenatide for the treatment of type 2 diabetes mellitus. Expert
Opinion on Drug Discovery. 2014 aug 14;1-29. Tilgængelig fra:
10.1517/17460441.2014.942638
Almdal TP, Handlos LN, Valerius M, Juul E, Nielsen KE, Vistisen D et al. Glycaemic threshold for diabetes-specific retinopathy among individuals from
Saudi Arabia, Algeria and Portugal. Diabetes research and clinical practice.
2014 mar;103(3):e44-6. Tilgængelig fra: 10.1016/j.diabres.2013.12.023
19. Comerma-Steffensen S, Grann M, Andersen C, Rungby J, Simonsen U.
Cardiovascular effects of current and future anti-obesity drugs. Current Vascular Pharmacology. 2014 maj;12(3):493-504.
Ampudia-Blasco FJ, Benhamou PY, Charpentier G, Consoli A, Diamant M,
Gallwitz B et al. A Decision Support Tool for Appropriate Glucose-Lowering
Therapy in Patients with Type 2 Diabetes. Diabetes Technology & Therapeutics. 2014 okt 27;17(3). Tilgængelig fra: 10.1089/dia.2014.0260
Glucometabolic hormones and cardiovascular risk markers in antipsychotictreated patients. Journal of Clinical Psychiatry. 2014 sep;75(9):e899-905.
Tilgængelig fra: 10.4088/JCP.13m08820
Bagger JI, Knop FK, Lund A, Holst JJ, Vilsbøll T. Glucagon responses to increasing oral loads of glucose and corresponding isoglycaemic intravenous
glucose infusions in patients with type 2 diabetes and healthy individuals. Diabetologia. 2014 aug;57(8):1720-5. Tilgængelig fra: 10.1007/s00125-014-32642
21. Færch K, Carstensen B, Almdal TP, Jørgensen ME. Improved survival among
patients with complicated type 2 diabetes in Denmark: a prospective study (20022010). The Journal of clinical endocrinology and metabolism. 2014
apr;99(4):E642-6. Tilgængelig fra: 10.1210/jc.2013-3210
Bak MJ, Wewer Albrechtsen NJ, Pedersen JH, Hartmann B, Christensen M,
Vilsbøll T et al. Specificity and sensitivity of commercially available assays for
glucagon and oxyntomodulin measurement in human. European journal of endocrinology / European Federation of Endocrine Societies. 2014 jan
10;170:529-538. Tilgængelig fra: 10.1530/EJE-13-0941
22. Gejl M, Rungby J, Brock B, Gjedde A. At the Centennial of Michaelis and Menten,
Competing Michaelis-Menten Steps Explain Effect of GLP-1 on Blood-Brain Transfer and Metabolism of Glucose. Basic & clinical pharmacology & toxicology. 2014
aug;115(2):162-71. Tilgængelig fra: 10.1111/bcpt.12240
Bak MJ, Wewer Albrechtsen NJ, Pedersen J, Knop FK, Vilsbøll T, Jørgensen
NB et al. Specificity and sensitivity of commercially available assays for glucagon-like peptide-1 (GLP-1): implications for GLP-1 measurements in clinical
studies. Diabetes, Obesity and Metabolism Online. 2014 nov;16(11):1155-64.
Tilgængelig fra: 10.1111/dom.12352
23. Gejl M, Lerche S, Mengel A, Møller N, Bibby BM, Smidt K et al. Influence of GLP-1
on myocardial glucose metabolism in healthy men during normo- or hypoglycemia.
P L o S One. 2014;9(1):e83758. Tilgængelig fra: 10.1371/journal.pone.0083758
7.
Bennett C, Klingenberg SL, Langholz E, Gluud LL. Tranexamic acid for upper
gastrointestinal bleeding. Cochrane Database of Systematic Reviews. 2014
nov 21;11:CD006640. Tilgængelig fra: 10.1002/14651858.CD006640.pub3
24. Gluud LL, Knop FK, Vilsbøll T. Effects of lixisenatide on elevated liver transaminases: systematic review with individual patient data meta-analysis of randomised
controlled trials on patients with type 2 diabetes. B M J Open.
2014;4(12):e005325. Tilgængelig fra: 10.1136/bmjopen-2014-005325
8.
Brønden A, Hansen M, Sonne DP, Rohde U, Vilsbøll T, Knop FK. Sevelamer
in a diabetologist's perspective: a phosphate-binding resin with glucoselowering potential. Diabetes, Obesity and Metabolism. 2014 jul 9;17(2):116120. Tilgængelig fra: 10.1111/dom.12355
9.
25. Hansen M, Sonne DP, Knop FK. Bile acid sequestrants: glucose-lowering mechanisms and efficacy in type 2 diabetes. Current Diabetes Reports. 2014
maj;14(5):482. Tilgængelig fra: 10.1007/s11892-014-0482-4
Burisch J, Pedersen N, Cukovic-Cavka S, Brinar M, Kaimakliotis I, Duricova D
et al. East-West gradient in the incidence of inflammatory bowel disease in Europe: the ECCO-EpiCom inception cohort. Gut. 2014 apr;63(4):588-597. Tilgængelig fra: 10.1136/gutjnl-2013-304636
26. Hansen JC, Brock B, Bøtker HE, Gjedde A, Rungby J, Gejl M. Impact of glucagonlike peptide-1 on myocardial glucose metabolism revisited. Reviews in Endocrine
& Metabolic Disorders. 2014 sep;15(3):219-31. Tilgængelig fra: 10.1007/s11154014-9286-8
10. Burisch J, Pedersen N, Cukovic-Cavka S, Turk N, Kaimakliotis I, Duricova D et
al. Environmental factors in a population-based inception cohort of inflammatory
bowel disease patients in Europe - An ECCO-EpiCom study. Journal of Crohn's
& colitis. 2014;8(7):607. Tilgængelig fra: 10.1016/j.crohns.2013.11.021
11. Burisch J, Vegh Z, Pedersen N, Cuković-Čavka S, Turk N, Kaimakliotis I et al.
Health care and patients' education in a European inflammatory bowel disease
inception cohort: An ECCO-EpiCom study. Journal of Crohn's & colitis. 2014
aug 1;8(8):811-8. Tilgængelig fra: 10.1016/j.crohns.2013.12.023
12. Burisch J, Weimers P, Pedersen N, Cukovic-Cavka S, Vucelic B, Kaimakliotis I
et al. Health-related quality of life improves during one year of medical and surgical treatment in a European population-based inception cohort of patients with
inflammatory bowel disease--an ECCO-EpiCom study. Journal of Crohn's & colitis. 2014 sep 1;8(9):1030-42. Tilgængelig fra: 10.1016/j.crohns.2014.01.028
13. Burisch J, Pedersen N, Cukovic-Cavka S, Turk N, Kaimakliotis I, Duricova D et
al. Initial disease course and treatment in an inflammatory bowel disease inception cohort in Europe: the ECCO-EpiCom cohort. Inflammatory bowel diseases.
2014 jan;20(1):36-46. Tilgængelig fra: 10.1097/01.MIB.0000436277.13917.c4
14. Buse JB, Vilsbøll T, Thurman J, Blevins TC, Langbakke IH, Bøttcher SG et al.
Contribution of liraglutide in the fixed-ratio combination of insulin degludec and
liraglutide (IDegLira). Diabetes Care. 2014 nov;37(11):2926-33. Tilgængelig fra:
10.2337/dc14-0785
15. Calanna S, Scicali R, Di Pino A, Knop FK, Piro S, Rabuazzo AM et al. Alphaand beta-cell abnormalities in haemoglobin A1c-defined prediabetes and type 2
diabetes. Acta Diabetologica. 2014 aug;51(4):567-75. Tilgængelig fra:
10.1007/s00592-014-0555-5
16. Calanna S, Scicali R, Di Pino A, Knop FK, Piro S, Rabuazzo AM et al. Lipid
and liver abnormalities in haemoglobin A1c-defined prediabetes and type 2 diabetes. Nutrition, metabolism, and cardiovascular diseases : NMCD. 2014
jun;24(6):670-6. Tilgængelig fra: 10.1016/j.numecd.2014.01.013
34
27. Hare KJ, Bonde L, Svare JA, Randeva HS, Asmar M, Hørup Larsen SM et al.
Decreased plasma chemerin levels in women with gestational diabetes mellitus.
Diabetic Medicine Online. 2014 aug;31(8):936-40. Tilgængelig fra:
10.1111/dme.12436
28. Hemmingsen B, Schroll JB, Wetterslev J, Gluud C, Vaag A, Sonne DP et al.
Sulfonylurea versus metformin monotherapy in patients with type 2 diabetes: a
Cochrane systematic review and meta-analysis of randomized clinical trials and
trial sequential analysis. CMAJ open. 2014 jul;2(3):E162-75. Tilgængelig fra:
10.9778/cmajo.20130073
29. Idorn T, Knop FK, Jørgensen MB, Christensen M, Holst JJ, Hornum M et al.
Elimination and Degradation of Glucagon-like Peptide-1 and Glucose-Dependent
Insulinotropic Polypeptide in Patients with End-Stage Renal Disease. The Journal
of clinical endocrinology and metabolism. 2014 jul;99(7):2457-66. Tilgængelig fra:
10.1210/jc.2013-3809
30. Idorn T, Knop FK, Jørgensen M, Holst JJ, Hornum M, Feldt-Rasmussen B. Postprandial responses of incretin and pancreatic hormones in non-diabetic patients
with end-stage renal disease. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 2014;29(1):119-127. Tilgængelig fra: 10.1093/ndt/gft353
31. Ishøy PL, Knop FK, Broberg BV, Baandrup L, Fagerlund B, Jørgensen NR et al.
Treatment of antipsychotic-associated obesity with a GLP-1 receptor agonist-protocol for an investigator-initiated prospective, randomised, placebo-controlled,
double-blinded intervention study: the TAO study protocol. B M J Open.
32. Jensen TW, Hansen MS, Hørslev-Petersen K, Hyldstrup L, Abrahamsen B,
Langdahl BL et al. Periarticular and generalised bone loss in patients with early
rheumatoid arthritis: influence of alendronate and intra-articular glucocorticoid
treatment. Post hoc analyses from the CIMESTRA trial. Annals of the Rheumatic
Diseases. 2014 maj 9;73(6):1123-1129. Tilgængelig fra: 10.1136/annrheumdis2012-203171
33. Junker AE, Als-Nielsen B, Gluud C, Gluud LL. Dopamine agents for hepatic encephalopathy. Cochrane Database of Systematic Reviews. 2014 feb
10;2:CD003047. Tilgængelig fra: 10.1002/14651858.CD003047.pub3
50. Pedersen DS, Locht LJ, Tran TP, Markholt S, Rungby J, Larsen A. Toxicological
aspects of injectable gold-hyaluronan combination as a treatment for neuroinflammation. Histology and Histopathology. 2014 apr;29(4):447-56.
34. Jørgensen ME, Almdal TP, Faerch K. Reduced incidence of lower-extremity
amputations in a Danish diabetes population from 2000 to 2011. Diabetic Medicine Online. 2014 apr;31(4):443-447. Tilgængelig fra: 10.1111/dme.12320
51. Pottegård A, Bjerregaard BK, Larsen MD, Larsen KS, Hallas J, Knop FK et al. Use
of exenatide and liraglutide in Denmark: a drug utilization study. European journal
of clinical pharmacology. 2014 feb;70(2):205-214. Tilgængelig fra: 10.1007/s00228013-1595-4
35. Knop FK, Lund A, Madsbad S, Holst JJ, Krarup T, Vilsbøll T. Unprecedented
high insulin secretion in a healthy human subject after intravenous glucagon-like
peptide-1: a case report. BMC research notes. 2014;7:326. Tilgængelig fra:
10.1186/1756-0500-7-326
36. Kähler P, Grevstad B, Almdal T, Gluud C, Wetterslev J, Vaag A et al. Targeting
intensive versus conventional glycaemic control for type 1 diabetes mellitus: a
systematic review with meta-analyses and trial sequential analyses of randomised clinical trials. B M J Open. 2014;4(8):e004806. Tilgængelig fra:
10.1136/bmjopen-2014-004806
52. Prieto-Alhambra D, Lalmohamed A, Abrahamsen B, Arden NK, de Boer A, Vestergaard P et al. Oral bisphosphonate use and total knee/hip implant survival: validation of results in an external population-based cohort. Arthritis & Rheumatology.
2014 nov;66(11):3233-40. Tilgængelig fra: 10.1002/art.38789
53. Rhee NA, Ostoft SH, Holst JJ, Deacon CF, Vilsbøll T, Knop FK. The impact of
dipeptidyl peptidase 4 inhibition on incretin effect, glucose tolerance, and gastrointestinal-mediated glucose disposal in healthy subjects. European journal of endocrinology / European Federation of Endocrine Societies. 2014 sep;171(3):353-62.
Tilgængelig fra: 10.1530/EJE-14-0314
37. Larsen JR, Vedtofte L, Holst JJ, Oturai P, Kjær A, Corell CU et al. Does a GLP1 receptor agonist change glucose tolerance in patients treated with antipsychotic medications?: Design of a randomised, double-blinded, placebocontrolled clinical trial. B M J Open. 2014;4(3):e004227. Tilgængelig fra:
10.1136/bmjopen-2013-004227
54. Rhee NA, Vilmann P, Hassan H, Hendel JW, Holst JJ, Vilsbøll T et al. The use of
double-balloon enteroscopy in retrieving mucosal biopsies from the entire human
gastrointestinal tract. Scandinavian journal of gastroenterology. 2014 jul 7;1-7. Tilgængelig fra: 10.3109/00365521.2014.934912
38. Liang B, Soka M, Christensen AH, Olesen MS, Larsen AP, Knop FK et al. Genetic variation in the two-pore domain potassium channel, TASK-1, may contribute to an atrial substrate for arrhythmogenesis. Journal of Molecular and Cellular Cardiology. 2014;67:69-76. Tilgængelig fra: 10.1016/j.yjmcc.2013.12.014
55. Roed T, Kristoffersen US, Knudsen A, Wiinberg N, Lebech A-M, Almdal T et al.
Increased prevalence of coronary artery disease risk markers in patients with
chronic hepatitis C - a cross-sectional study. Vascular Health and Risk Management (Online). 2014;10:55-62. Tilgængelig fra: 10.2147/VHRM.S53557
39. Lund A, Bagger JI, Christensen M, Knop FK, Vilsbøll T. Glucagon and type 2
diabetes: the return of the alpha cell. Current Diabetes Reports. 2014
dec;14(12):555. Tilgængelig fra: 10.1007/s11892-014-0555-4
56. Rohde U, Gylvin S, Vilmann P, Friis SU, Langholz E, Vilsbøll T et al. Behandling
med duodenal-jejunal bypass-sleeve ved svær overvægt. Ugeskrift for Laeger.
2014;176(20):1874-77.
40. Lund A, Knop FK, Vilsbøll T. Glucagon-like peptide-1 receptor agonists for the
treatment of type 2 diabetes: differences and similarities. European journal of internal medicine. 2014 jun;25(5):407-14. Tilgængelig fra:
10.1016/j.ejim.2014.03.005
57. Rohde U, Gylvin S, Vilmann P, Friis SU, Langholz E, Vilsbøll T et al. Duodenaljejunal bypass sleeve - a potential alternative to bariatric surgery?. Ugeskrift for læger [online]. 2014 sep 8;176(37).
41. Lundby-Christensen L, Tarnow L, Hansen DL, Worm D, Naver LS, Hvolris LE et
al. Carotid intima-media thickness is reduced 12months after gastric bypass
surgery in obese patients with type 2 diabetes or impaired glucose tolerance.
Journal of Diabetes and its Complications. 2014 apr 2;28(4):517-22.
Tilgængelig fra: 10.1016/j.jdiacomp.2014.03.005
42. Mor A, Svensson E, Rungby J, Ulrichsen SP, Berencsi K, Nielsen JS et al. Modifiable clinical and lifestyle factors are associated with elevated alanine aminotransferase levels in newly diagnosed type 2 diabetes patients: results from
the nationwide DD2 study. Diabetes - Metabolism: Research and Reviews
(Online). 2014 nov;30(8):707-15. Tilgængelig fra: 10.1002/dmrr.2539
43. Nielsen JS, Rungby J, Christiansen JS, Vaag A, Friborg S, Sørensen HT et al.
DD2 - nye veje i behandlingen af type 2-diabetes. Ugeskrift for læger [online].
2014 jun 2;176(11A).
58. Shane E, Burr D, Abrahamsen B, Adler RA, Brown TD, Cheung AM et al. Atypical
subtrochanteric and diaphyseal femoral fractures: Second report of a task force of
the American Society for Bone and Mineral Research. Journal of bone and mineral
research : the official journal of the American Society for Bone and Mineral Research. 2014 jan;29(1):1-23. Tilgængelig fra: 10.1002/jbmr.1998
59. Sonne DP, Hansen M, Knop FK. MECHANISMS IN ENDOCRINOLOGY: Bile acid
sequestrants in type 2 diabetes: potential effects on GLP1 secretion. European
journal of endocrinology / European Federation of Endocrine Societies. 2014
aug;171(2):R47-R65. Tilgængelig fra: 10.1530/EJE-14-0154
60. Sonne DP, Lund A, Faber J, Holst JJ, Vilsbøll T, Knop FK. On the role of gallbladder emptying and incretin hormones for nutrient-mediated TSH suppression in patients with type 2 diabetes. Endocrine Connections. 2014 dec;3(4):193-9.
Tilgængelig fra: 10.1530/EC-14-0088
44. Nissen AGB, Christensen M, Knop FK, Vilsbøll T, Holst JJ, Hartmann B. Glucose-dependent Insulinotropic Polypeptide Inhibits Bone Resorption in Humans.
The Journal of clinical endocrinology and metabolism. 2014 aug 21;jc20142547.
Tilgængelig fra: 10.1210/jc.2014-2547
61. Sonne DP, Rehfeld JF, Holst JJ, Vilsbøll T, Knop FK. Postprandial gallbladder
emptying in patients with type 2 diabetes: potential implications for bile-induced
secretion of glucagon-like peptide 1. European journal of endocrinology / European Federation of Endocrine Societies. 2014 okt;171(4):407-19. Tilgængelig fra:
10.1530/EJE-14-0309
45. Noiesen E, Trosborg I, Bager L, Herning M, Lyngby C, Konradsen H. Constipation - prevalence and incidence among medical patients acutely admitted to
62. Storgaard H, Mortensen B, Almdal T, Laub M, Tarnow L. At least one in three
people with Type 2 diabetes mellitus referred to a diabetes centre has symptomatic obstructive sleep apnoea. Diabetic Medicine. 2014 nov;31(11):1460-7.
Tilgængelig fra: 10.1111/dme.12477
46. Nygaard SB, Larsen A, Knuhtsen A, Rungby J, Smidt K. Effects of zinc supplementation and zinc chelation on in vitro β-cell function in INS-1E cells. BMC research notes. 2014;7:84. Tilgængelig fra: 10.1186/1756-0500-7-84
63. Storgaard H, Gluud LL, Christensen M, Knop FK, Vilsbøll T. The effects of sodium-glucose co-transporter 2 inhibitors in patients with type 2 diabetes: protocol for
a systematic review with meta-analysis of randomised trials. B M J Open.
2014;4(8):e005378.
47. Ostoft SH, Bagger JI, Hansen T, Pedersen O, Faber J, Holst JJ et al. GlucoseLowering Effects and Low Risk of Hypoglycemia in Patients With Maturity-Onset
Diabetes of the Young When Treated With a GLP-1 Receptor Agonist: A Double-Blind, Randomized, Crossover Trial. Diabetes Care. 2014 jul;37(7):1797805. Tilgængelig fra: 10.2337/dc13-3007
64. Støy J, Grarup N, Hørlyck A, Ibsen L, Rungby J, Poulsen PL et al. Blood pressure
levels in male carriers of Arg82Cys in CD300LG. P L o S One.
65. Suresh E, Pazianas M, Abrahamsen B. Safety issues with bisphosphonate therapy for osteoporosis. Rheumatology (Oxford, England). 2014 jan;53(1):19-31.
Tilgængelig fra: 10.1093/rheumatology/ket236
48. Ostoft SH, Bagger JI, Hansen T, Pedersen O, Holst JJ, Knop FK et al. Incretin
effect and glucagon responses to oral and intravenous glucose in patients with
maturity-onset diabetes of the young-type 2 and type 3. Diabetes. 2014
aug;63(8):2838-44. Tilgængelig fra: 10.2337/db13-1878
49. Pedersen N, Thielsen P, Martinsen L, Bennedsen M, Haaber A, Langholz E et
al. eHealth: Individualization of Mesalazine Treatment Through a Self-managed
Web-based Solution in Mild-to-moderate Ulcerative Colitis. Inflammatory bowel
diseases. 2014 dec;20(12):2276-85. Tilgængelig fra:
10.1097/MIB.0000000000000199
35
66. Svensson E, Mor A, Rungby J, Berencsi K, Nielsen JS, Stidsen J et al. Lifestyle
and clinical factors associated with elevated C-reactive protein among newly diagnosed Type 2 diabetes mellitus patients: a cross-sectional study from the nationwide DD2 cohort. B M C Endocrine Disorders. 2014;14:74. Tilgængelig fra:
10.1186/1472-6823-14-74
67. Telinius N, Baandrup U, Rumessen J, Pilegaard H, Hjortdal VE, Aalkjaer C et
al. The human thoracic duct is functionally innervated by adrenergic nerves. A J
P: Heart and Circulatory Physiology (Online). 2014 jan;306(2):H206-13. Tilgængelig fra: 10.1152/ajpheart.00517.2013
68. van Poppel PCM, van Asseldonk EJP, Holst JJ, Vilsbøll T, Netea MG, Tack CJ.
The interleukin-1 receptor antagonist anakinra improves first-phase insulin secretion and insulinogenic index in subjects with impaired glucose tolerance. Diabetes, Obesity and Metabolism Online. 2014 dec;16(12):1269-73. Tilgængelig
fra: 10.1111/dom.12357
69. Vrieze A, Out C, Fuentes S, Jonker L, Reuling I, Kootte RS et al. Vancomycin
decreases insulin sensitivity and is associated with alterations in intestinal microbiota and bile acid composition in obese subjects with metabolic syndrome.
Journal of Hepatology. 2014 apr;60(4):824-831. Tilgængelig fra:
10.1016/j.jhep.2013.11.034
70. Wewer Albrechtsen NJ, Hartmann B, Veedfald S, Windeløv JA, Plamboeck A,
Bojsen-Møller KN et al. Hyperglucagonaemia analysed by glucagon sandwich
ELISA: nonspecific interference or truly elevated levels?. Diabetologia. 2014
sep;57(9):1919-26. Tilgængelig fra: 10.1007/s00125-014-3283-z
71. Wilkens Knudsen A, Jensen J-EB, Nordgaard-Lassen I, Almdal T, Kondrup J,
Becker U. Nutritional intake and status in persons with alcohol dependency: data from an outpatient treatment programme. European Journal of Nutrition. 2014
okt;53(7):1483-92. Tilgængelig fra: 10.1007/s00394-014-0651-x
Kommentar/debat
72. Grove E, Abrahamsen B, Vestergaard P. Response: Is heart failure a debatable
end-point for bisphosphonate treatment in an older osteoporotic population?
(letter). Journal of internal medicine. 2014 feb;275(2):198. Tilgængelig fra:
10.1111/joim.12151
73. Idorn T, Knop FK, Jørgensen M, Holst JJ, Hornum M, Feldt-Rasmussen B. The
authors reply:. Kidney International. 2014 jan;85(1):212-3. Tilgængelig fra:
10.1038/ki.2013.410
74. Wildt S, Lassen IN, Rumessen JJ. Incorrect citation and analysis in metaanalysis. Inflammatory Bowel Diseases. 2014;20(12):E25. Tilgængelig fra:
10.1097/MIB.0000000000000249
Glucometabolic Hormones and Cardiovascular Risk Markers in AntipsychoticTreated Patients. Schizophrenia Research. 2014 apr;153(Suppl. 1):90.
Ph.d.-afhandling
76. Christensen M. Glucose-dependent insulinotropic polypeptide (GIP): Effects on
insulin and glucagon secretion in humans. 2014.
77. Sonne DP. On the role of gallbladder emptying and bile acids for postprandial
GLP-1 secretion. 2014.
78. Østoft SH. Incretin hormones and maturity onset diabetes of the young – pathophysiological implications and antidiabetic treatment potential. 2014.
36
Forskningstemaer
2.
Berthelsen CB, Lindhardt Damsgaard T, Frederiksen K. Maintaining Unity - relatives in older patients' fast-track treatment programmes. A grounded theory study.
Journal of Advanced Nursing. 2014 apr 1;70(12):2746-56. Tilgængelig fra:
10.1111/jan.12407
3.
Boeckstyns MEH, Herzberg G. Periprosthetic osteolysis after total wrist arthroplasty. Journal of Wrist Surgery. 2014 maj;3(2):101-6. Tilgængelig fra: 10.1055/s-00341372532
4.
Boeckstyns MEH, Merser S. Psychometric properties of two questionnaires in the
context of total wrist arthroplasty. Danish Medical Bulletin (Online). 2014
nov;61(11):A4939.
5.
Boeckstyns MEH, Toxværd A, Bansal M, Vadstrup LS. Wear particles and osteolysis in patients with total wrist arthroplasty. Journal of Hand Surgery (American Volume). 2014 dec;39(12):2396-404. Tilgængelig fra: 10.1016/j.jhsa.2014.07.046
6.
Boeckstyns MEH. Wrist arthroplasty--a systematic review. Danish Medical Bulletin
(Online). 2014 maj;61(5):A4834.
7.
Bøttcher Berthelsen C, Lindhardt Damsgaard T, Frederiksen K. Inhibiting Interference - a grounded theory of health professionals' pattern of behaviour related to the
relatives of older patients in fast-track treatment programmes. Scandinavian journal
of caring sciences. 2014 sep;28(3):609-17. Tilgængelig fra: 10.1111/scs.12126
8.
Christensen JF, Jones LW, Tolver A, Jørgensen LW, Andersen JL, Adamsen L et
al. Safety and efficacy of resistance training in germ cell cancer patients undergoing
chemotherapy: a randomized controlled trial. B J C. 2014 jul 1;111(1):8-16. Tilgængelig fra: 10.1038/bjc.2014.273
9.
Dahl JB, Nielsen RV, Wetterslev J, Nikolajsen L, Hamunen K, Kontinen VK et al.
Post-operative analgesic effects of paracetamol, NSAIDs, glucocorticoids,
gabapentinoids and their combinations: a topical review. Acta anaesthesiologica
Scandinavica. 2014 aug 14;58(10):1165-1181. Tilgængelig fra: 10.1111/aas.12382
 Pårørendes rolle under den ældre patients accelererede operationsforløb ved total hofte- eller knæalloplastik – praksisforankret teoriudvikling
 Udvikling og afprøvning af et empowermentorienteret undervisningsprogram rettet mod rehabiliteringsperioden efter et accelereret hoftealloplastikforløb
 Fremmedelegemeinfektion - et dyreeksperimentelt
studium omfattende undersøgelse af vaccination
som forebyggende behandling af proteseinfektion
 PROM
 RSA
 Problemstillinger i forhold til fast-track forløb
 Problemstillinger i forhold til proteserelateret infektion
Ph.d. studerende
Mikkel Rathsach Andersen, læge
Kirsten Szöts, sygeplejerske, cand.cur.
10. Dan-Nielsen S, Wewer V, Paerregaard A, Hansen LF, Nielsen RG, Lange A et al.
Does infliximab prevent colectomy in acute and chronic active ulcerative colitis?.
Journal of Pediatric Gastroenterology and Nutrition. 2014 jun;58(6):768-72.
Tilgængelig fra: 10.1097/MPG.0000000000000340
Anders Odgaard, overlæge
Henrik Morville Schrøder, overlæge
11.
Eriksen P, Bartels EM, Altman RD, Bliddal H, Juhl CB, Christensen R. Risk of
bias and brand explain the observed inconsistency in trials on glucosamine for
symptomatic relief of osteoarthritis: a meta-analysis of placebo-controlled trials.
Arthritis Care & Research. 2014 dec;66(12):1844-55. Tilgængelig fra:
10.1002/acr.22376
12.
Grevstad U, Mathiesen O, Lind T, Dahl JB. Effect of adductor canal block on pain
in patients with severe pain after total knee arthroplasty: a randomized study with
individual patient analysis. British Journal of Anaesthesia. 2014 jan 8;112(5):91219. Tilgængelig fra: 10.1093/bja/aet441
13.
Gudmann KNS, Wang J, Hoielt S, Chen P, Siebuhr AS, He Y et al. Cartilage
turnover reflected by metabolic processing of type II collagen: a novel marker of
anabolic function in chondrocytes. International Journal of Molecular Sciences
(Online). 2014;15(10):18789-803. Tilgængelig fra: 10.3390/ijms151018789
14.
Gvozdenovic R, Boeckstyns M. Collateral ligament reconstruction of the chronic
thumb injury with bio-tenodesis screw fixation. Techniques in Hand & Upper Extremity Surgery. 2014 dec;18(4):160-4. Tilgængelig fra:
10.1097/BTH.0000000000000058
15.
Hansen JB, Juhl CB, Boutron I, Tugwell P, Ghogomu EAT, Pardo Pardo J et al.
Assessing bias in osteoarthritis trials included in Cochrane reviews: protocol for a
meta-epidemiological study. B M J Open. 2014;4(10):e005491. Tilgængelig fra:
10.1136/bmjopen-2014-005491
16.
Henriksen M, Creaby MW, Lund H, Christensen R, Juhl CB. Is there a causal link
between knee loading and knee osteoarthritis progression?: A systematic review
and meta-analysis of cohort studies and randomised trials. B M J Open.
17.
Husted H, Schrøder H, Odgaard A, Troelsen A. Knæartrose - diagnostik og
behandling. Ugeskrift for læger [online]. 2014 jun 9;176(12):V03130155 .
Thomas Lind, overlæge
Søren Solgaard, overlæge
Niels Søe, overlæge
Michel Boeckstyns, overlæge
Claus Hjort Jensen, overlæge
Lars Vadstrup, overlæge
Rasmus Nielsen, 1.reservelæge
Carsten Bogh Juhl, Forsknings- og udviklingsfysioterapeut
Susanne Boel, Forsknings- og udviklingsergoterapeut
Anders Odgaard
Udviklings-/Forskningsansvarlig sygeplejerske
Louise Bager, klinisk sygeplejespecialist
Publikationer 2014
1.
Andersen M, Boesen M, Ellegaard K, Christensen R, Söderström K, Søe N et
al. Synovial explant inflammatory mediator production corresponds to rheumatoid arthritis imaging hallmarks: a cross-sectional study. Arthritis Research &
Therapy. 2014;16(3):R107. Tilgængelig fra: 10.1186/ar4557
37
18. Husted H, Schrøder H, Odgaard A, Troelsen A. Knæartrose set fra ortopædkirurgens synsvinkel. Ugeskrift for læger [online]. 2014 jun 9;176(12):1139-1142.
12/2014.
19. Høgdal N, Juhl CB, Aadahl M, Gluud C. Early preventive exercises versus usual
care does not seem to reduce trismus in patients treated with radiotherapy for
cancer in the oral cavity or oropharynx: A randomised clinical trial. Acta oncologica (Stockholm, Sweden). 2014 sep 17;54:80-87. Tilgængelig fra:
10.3109/0284186X.2014.954677
20. Juhl CB, Christensen R, Roos EM, Zhang W, Lund H. Impact of exercise type
and dose on pain and disability in knee osteoarthritis: a systematic review and
meta-regression analysis of randomized controlled trials. Arthritis & Rheumatism. 2014 mar;66(3):622-36. Tilgængelig fra: 10.1002/art.38290
21. Jæger P, Koscielniak-Nielsen ZJ, Schrøder HM, Mathiesen O, Henningsen MH,
Lund J et al. Adductor canal block for postoperative pain treatment after revision
knee arthroplasty: a blinded, randomized, placebo-controlled study. P L o S
One. 2014;9(11):e111951. Tilgængelig fra: 10.1371/journal.pone.0111951
22. Jørgensen CC, Kjaersgaard-Andersen P, Solgaard S, Kehlet H. Hip dislocations
after 2,734 elective unilateral fast-track total hip arthroplasties: incidence, circumstances and predisposing factors. Archives of orthopaedic and trauma surgery. 2014;134 (11):1615-1622. Tilgængelig fra: 10.1007/s00402-014-2051-3
23. Krenk L, Kehlet H, Bæk Hansen T, Solgaard S, Soballe K, Rasmussen LS.
Cognitive dysfunction after fast-track hip and knee replacement. Anesthesia and
Analgesia. 2014;118(5):1034-40. Tilgængelig fra:
10.1213/ANE.0000000000000194
24. Lindberg-Larsen M, Jørgensen CC, Bæk Hansen T, Solgaard S, Odgaard A,
Kehlet H. Re-admissions, re-operations and length of stay in hospital after
aseptic revision knee replacement in Denmark: a two-year nationwide study.
The bone & joint journal. 2014;96-B(12):1649-56. Tilgængelig fra:
10.1302/0301-620X.96B12.33621
25. Mackey AL, Karlsen A, Couppé C, Mikkelsen UR, Nielsen RH, Magnusson SP
et al. Differential satellite cell density of type I and II fibres with lifelong endurance running in old men. Acta physiologica (Oxford, England). 2014
mar;210(3):612-27. Tilgængelig fra: 10.1111/apha.12195
26. Nielsen RH, Clausen NM, Schjerling P, Larsen JO, Martinussen T, List EO et al.
Chronic alterations in growth hormone/insulin-like growth factor-I signaling lead
to changes in mouse tendon structure. Matrix biology : journal of the International Society for Matrix Biology. 2014 feb;34:96-104. Tilgængelig fra:
10.1016/j.matbio.2013.09.005
27. Noiesen E, Trosborg I, Bager L, Herning M, Lyngby C, Konradsen H. Constipation - prevalence and incidence among medical patients acutely admitted to
28. Pedersen EG, Pottegård A, Hallas J, Friis S, Hansen K, Jensen PEH et al. Myasthenia and risk of cancer: a population-based case-control study. European
journal of neurology : the official journal of the European Federation of Neurological Societies. 2014 maj;21(5):773-8. Tilgængelig fra: 10.1111/ene.12383
29. Skou ST, Simonsen ME, Odgaard A, Roos EM. Predictors of long-term effect
from education and exercise in patients with knee and hip pain. Danish Medical
Bulletin (Online). 2014 jul;61(7):A4867.
30. Solgaard S, Kjersgaard AG. Increased risk for early periprosthetic fractures after uncemented total hip replacement. Danish Medical Bulletin (Online). 2014
feb;61(2):A4767.
31. Sun S, Bay-Jensen A-C, Karsdal MA, Siebuhr AS, Zheng Q, Maksymowych WP
et al. The active form of MMP-3 is a marker of synovial inflammation and cartilage turnover in inflammatory joint diseases. B M C Musculoskeletal Disorders.
2014;15:93. Tilgængelig fra: 10.1186/1471-2474-15-93
32. Szöts K, Konradsen H, Solgaard S, Ostergaard B. Telephone follow-up by
nurse following total knee arthroplasty - protocol for a randomized clinical trial
(NCT 01771315). B M C Nursing. 2014;13:14. Tilgængelig fra: 10.1186/14726955-13-14
33. Vadstrup LS, Jørring S, Bernt P, Boeckstyns MEH. Base fractures of the fifth
proximal phalanx can be treated conservatively with buddy taping and immediate mobilisation. Danish Medical Bulletin (Online). 2014 aug;61(8):A4882.
38
Røntgen- og skannings afd.
Forskningstemaer
 Screening for lungecancer med CT
 Optimal billeddiagnostik ved primær hyperparathy-
Publikationer 2014
reoidisme (Skintigrafi, SPECT, PET og 4DCT).
 Effekt på arteriel inflammation ved biologisk be-
1.
Bækgaard N, Just S, Foegh P. Which criteria demand additive stenting during
catheter-directed thrombolysis?. Phlebology / Venous Forum of the Royal Society
of Medicine. 2014 maj 19;29(1 suppl):112-118. Tilgængelig fra:
10.1177/0268355514528842
2.
Egsmose EL, Birkvig M, Buhl T, Madsen OR. FRAX fracture risk in women with a
recent fracture of the distal forearm: agreement between assessments with and
without bone mineral density and impact of measurement side in the individual patient. Clinical rheumatology. 2014 maj 14. Tilgængelig fra: 10.1007/s10067-0142640-0
3.
Greve SV, Blicher TM, Blyme A, Sehestedt T, Hansen TW, Rasmussen SL et al.
Association between albuminuria, atherosclerotic plaques, elevated pulse wave velocity, age, risk category and prognosis in apparently healthy individuals. Journal of
hypertension. 2014 maj;32(5):1034-41; discussion 1041. Tilgængelig fra:
10.1097/HJH.0000000000000147
4.
Jensen P, Zachariae C, Christensen R, Geiker NRW, Schaadt BK, Stender S et al.
10.2340/00015555-1824
5.
Konge L, Albrecht-Beste E, Nielsen MB. Virtual-reality simulation-based training in
ultrasound. Ultraschall in der Medizin (Stuttgart, Germany : 1980). 2014
apr;35(2):95-7. Tilgængelig fra: 10.1055/s-0034-1366191
6.
Pallisgaard J, Stride NO, Myschetzky PS, Bech J. Fisteldannende kæmpekoronararterieaneurisme hos 62-årig kvinde indlagt med brystsmerter. Ugeskrift for læger
[online]. 2014 dec 15.
7.
Saghir Z, Dirksen A, Ashraf H, Bach KS, Brodersen J, Clementsen PF et al. Screening for lungecancer med lavdosis-CT - danske og udenlandske resultater. Ugeskrift for læger [online]. 2014 okt 13;176(42):V05140283.
8.
Strandberg C, Wilkens R. Transabdominal ultralydskanning af tarmen er et godt
supplement ved diagnostik af tarmsygdomme. Ugeskrift for læger. 2014 mar
3;176(5):451-454. V12120694.
9.
Thamsborg AKM, Krakauer M, Fahrenkrug L. Tilfældigt fund af urinblære i scrotum
ved scintigrafi. Ugeskrift for læger [online]. 2014 jul 21;176(30).
handling af reumatoid artrit (CT, FDG-PET/CT og Ultralyd)
 Bedre estimering af forventet postoperativ lungefunktion på lungelap-niveau (Lungeskintigrafi med
SPECT/CT) hos patienter med lungecancer.
 Undersøge effekt af liraglutide (glucagon-like peptide-1 (GLP-1)) receptoragonist på glukosetolerance
og risiko for at udvikle type 2 diabetes hos kvinder
med tidligere gestationel diabetes. Undersøges med
bl. a. helkrops DXA-skanning.
 Effekt af duodenal-jejunal bypass sleeve, undersøgt
blandt andet med DXA skanning (DJBS).
 Afdække årsager til astma og allergi. Undersøgelse
af børn (COPSAC 2010) med bl. a. helkrops DXAskanning.
 Endokrine forandringer efter gastrisk bypass kirurgi,
undersøgt blandt andet med helkrops DXA-skanning
(RYGB).
 Sammenhængen mellem fedtlever og glukagon resistens. Undersøgelse af normalvægtige og overvægtige med blandt andet helkrops DXA-skanning
(SIRG-1)."
 Verdict-projekt - Hvor vidt kan hjerte-CT erstatte
KAG i den akutte fase ?
Forskningsansvarlige overlæger
Peter Sand Myschetzsky, overlæge Radiologisk
Martin Krakauer, overlæge Nuklearmedicinsk
39

Forskningsberetning for Gentofte Hospital 2014

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