The Basic of ALS Assistance - Charlottesville
Transcription
The Basic of ALS Assistance - Charlottesville
The Basic of ALS Assistance Charlottesville-Albemarle Rescue Squad, Inc. Introduction • As a CARS member, you are an integral part of a team • • whose goal is to take care of a sick patient. Regardless of your training level, you will be called upon at times to set up an IV line, an albuterol treatment, or to get drugs from the box. Therefore, a basic understanding of the box will help the team out tremendously. The contents and organization of the box changed in October, 2001 with implementation of new protocols. The additional information included here is never to be used independent of the direct supervision and request of a certified ALS provider. Disclaimers • For the sake of clarity, gloves have not been • used in most of the photographs. It should be noted that you should ALWAYS WEAR GLOVES when taking care of patients. This presentation presents you with the basics of the drug box to help you be even more helpful on an ALS call. Never do anything from this presentation without an AIC asking you to do so. Table of Contents I. II. III. IV. Basic drug box anatomy Setting up an IV line Setting up a nebulizer treatment Preparing medication – – – – – V. VI. Medication vials Bristojet injectors Tubex injector Glass ampules Administer Nitroglycerin and Nitropaste. Basic drug review Written Test Section I - Drug box anatomy • There are four basic compartments to the box: three drawers and the bottom of the box. • The next few pages contain basic outlines of the drawers’ contents. Don’t try to memorize them, but get the basic layout. • Section V will outline these contents in more detail, and will give you a chance to test you memory. Opening the box… (Okay, you think, this is dumb. How hard can it be? Actually, very if you don’t know a few things…) • Start by breaking the pharmacy’s red seal tag by tearing it off. ONLY do this if the released ALS AIC asks you to do so. • Then, unlatch the front and two side latches. • Open the front flap. • The pull out the top drawer a few inches. • Only then will you be able to open the large top, and the box opens like a tackle box. NOTE: The drug boxes are sealed in the pharmacy following a thorough check by a pharmacist. Check for the intact seal each time you look for the presence of the box. Step 2 Step 1 General Layout • There are three drawers and a • • • • bottom basin. Top drawer: IV catheters, needles and syringes, and gray top tube. Middle drawer: Most medications. Bottom drawer: ‘Code’ (cardiac arrest) drugs. Bottom basin: IV fluids, tubing, albuterol, a few more drugs, arm splints, sharps container and pharmacy complaint form. Top Drawer IV Catheters 2 – 14 g (orange) 2 – 16 g (gray) 3 – 18 g (green) 3 – 20 g (pink) 2 – 22 g (yellow) 2 – 24 g (blue) Injection materials IV starting materials 2 pairs of gloves 2 tourniquets 3 – 2x2’s 3 – 4x4’s 2 – 1 cc syringes with needle, ‘Tb syringe’ 2 – 3 cc syringes with needle 2 – 5 cc syringe without needle 2 – 10 cc syringe without needle 2 heparin locks Assorted needles Random IV Materials 16 – Alcohol preps 1 – Roll of Transpore tape (“IV tape”) 2 – 10 cc saline flush bottles 1 – Blood sugar tube (see later) 2 – Versed 5 mg/1 cc 4 – Epinephrine 1:1,000 1 mg/1 cc 1 - Narcan 4 mg/10 cc 1 – Dopamine HCl 200 mg/5 cc, to mix 4 – Magnesium Sulfate 1 mg/2 cc 2 – Nitropaste packets and application paper Aspirin 81 mg tablets 1 – Solu-medrol 125 mg 3 – Metoprolol 5 mg/5 cc 1 – Bottle of nitroglycerin 1 – Epinephrine 1:1,000 30 mg/30 cc 1 – Lidocaine 1 g/25 cc 1 – Glucagon 1 mg, needs to be mixed 2 – Morphine Sulfate 10 mg/1cc 3 – Lasix 40 mg/4 cc 1 – Valium 10 mg/2 cc 2 - Benadryl 50 mg/1 cc 3 – Adeonsine 6 mg/2 cc Middle Drawer 2 – 14 g 2¼” Catheters For chest decompression 2 – Vasopressin 20 Units/1 cc 4 – Epinephrine 1:10,000 1 mg/10 cc 4 – Epinephrine 1:10,000 1 mg/10 cc 2 – Lidocaine HCl 100 mg/5 cc 2 – Lidocaine HCl 100 mg/5 cc 1 – Calcium Chloride 1 g/10 cc 4 – Atropine 1 mg/10 cc Bottom Drawer Bottom of Box 2 – Ar m boa rds 2 – T-port extension sets 1 – Sharps container 1 – Albuterol hand held nebulizer set-up 4 – Albuterol bullets 1 – Ipatropium bullet 2 – 30 cc syringes 2 – Macrodrip tubing sets 2 – Minidrip tubing sets 2 – 1,000 cc bags of Normal Saline 2 – 250 cc bags of D5W rd bag 1 – Biohaza list ox contents 1 – Drug b form 1 – Problem 2 – Dextrose 50% 25 g/50 cc 2 – Sodium Bicarbonate 50 mEq/50 cc Section II - Intravenous Lines • IV lines are started for many reasons, including administering fluid to hypovolemic patients and as a route to give medications. • The basic set-up involves: – The fluid to be infused, connected to … – Tubing, which is connected to an… – Extension set... – Which connects to the IV catheter in the vein. Fluids Normal Saline (NS) – 1,000 cc/bag – ALWAYS used in trauma and cardiac arrest. Often used for patients with chest pain and other medical complaints. – The fluid is a salt, which is infused into the bloodstream, part of which stays in the vasculature. – Consider it the default fluid. • Dextrose 5% - 250 cc/bag 0.9% Sodium Chloride aka “Normal Saline” – Used for mixing drips of medications. – Does not stay in vasculature, so it cannot be used to resuscitate a hypotensive patient. • The bottom line: ASK the AIC which fluid they want, but you will almost always use saline. 5% Dextrose in water aka “D5W” Tubing • The tubing connects the fluid bag to the • • extension set Drip chamber determines maximum flow rate Macrodrip, aka ‘big drip’ or ’10-drop’ tubing – 10 drops make 1 cc (1 ml) – Has a wide drip chamber which makes big drops, allowing quick delivery of high volumes • Microdrip, aka ‘little drip’ or ’60 drop’ tubing – 60 drops make 1 cc (1 ml) – Has a small, needle-like dripper which allows counting of drops to titrate medication drips • Again, ask the AIC which tubing they want. Off-clamp Tubing Anatomy Drip chamber From the fluid bag down to the extension set • Drip chamber – Holds a reservoir of fluid preventing infusion of air bubbles Flow – Allows observation of flow rate regulator • Clamp Drug port – Allows immediate cessation of flow – Always check here if there is NO flow when you ‘open up the line.’ aka ‘opening up the line.’ • Towards the patient decreases rate. – Comes packaged in the open position. • Drug port – Rubber-covered allows repeated needle puncture for medication administration Incr eas es • Towards the fluid bag increases flow rate, D ec r e a ses flow – Manipulates flow flow • Flow regulator Extension set • Should be placed on all IV’s • Serves as a reversible, one-way • • • connector between tubing and the IV catheter. Allows the ER staff to draw blood and inject medications without resticking the patient. Provides a very proximal medication port for medications that have very short half-lives, eg adenosine. Some providers do not like to use it because of the twisting port used to attach to the catheter. However, it is of tremendous benefit to the patient, so use them ☺ g bin u T IV Extension Tubing Disposable caps One-way valve To Clamp IV ca th et er Choosing the IV catheter • IV supplies are found in the top • • drawer of the drug box. The catheters come in different diameters and lengths. The packages are color coded by size as shown in the middle. You can see the catheters come as a big mess, so knowing the colors saves lots of time. The size, or gauge (g), is written in the upper left corner of the package. This number represents 1/(diameter of catheter in inches), so 14g is 1/14” in diameter, and is the biggest catheter. Next to it is marked the length of catheter. 14 g - Orange 16 g – Gray 18 g – Green 20 g – Pink 22 g – Blue 24 g - Yellow Anatomy of IV catheters • The plastic catheter is the connection • • between the IV tubing and the patient’s vein. Most of the new catheters are clear; they are not defective. The contraption shown in to top figure is how the catheter-over-needle is packaged. PROCEUDRE: The protective cap is removed, and after cleansing the skin with alcohol, the needle-catheter combination is introduced through the patient’s skin, into a superficial vein. Blood flows back through the needle, and into the flash chamber. The catheter is threaded over the needle and into the vein, and the needle withdrawn into the casing as shown in bottom figure. The needle is removed and tubing attached. Protective cap Needle Flash chamber Intravenous catheter Withdrawn needle “Setting up a line…” • Hopefully, you now understand the • • parts of a functional IV: a fluid bag, tubing, extension set and a catheter. “Setting up a line” is a common request of newer members, so you should know how to do this. This involves preconnecting the fluid, tubing and extension set and letting the fluid run through the line, getting rid of the air. Start by opening the box and removing a bag of fluid, tubing and an extension set. Your defaults should be normal saline and a macrodrip (10 drop) tubing, unless your AIC tells you differently. However, ALWAYS ask what the AIC wants set up. Extension set Tubing set Normal Saline Precut edge The fluid bag • Packaging for both D5W and saline bags have only one right way to be opened…and several wrong, though creative ways. • There is a precut edge in the • • • upper left corner. Pull the corner as shown down the length of the bag. Remove the bag and pull off the blue cover. The medication port is just that, and is not to be removed. At this point, hang the bag on the hooks in the truck (by the precut hole in the bag) or have a bystander hold it. Medication/ fluid withdrawal port Preparing the tubing and extension set Remove cap Extension set contents • Open the tubing by pulling the package • • apart at the sides. It tears easily at the serrated edge. Also open the extension set. The extension set comes with everything as shown. The blue cap should be removed by twisting off, the one way valve must then be tightened1, or it will leak or fall off. Leave the distal cap on until ready to connect to the catheter to keep the tip clean. Then attach the distal end of the tubing to the one way valve of the extension set as shown2. Secure the two by twisting cap as shown3. Tighten (1) Ensure clamp is off Leave cap on 3 2 Connecting the tubing to fluid • Remove the cap that covers the drip • chamber (not shown1). Then grip the nipple tightly with one hand2 and squeeze the drip chamber as shown with the other hand3, and push up into the bag with a twisting motion. The beveled edge will pierce the membrane and allow fluid to flow into drip chamber. Remember that once you do this, removing the tubing from that port will lead to a high volume leakage of fluid onto the floor…this constitutes poor form. 2. Grip tightly 1. Remove cap 3. Squeeze and twist up Important slide The drip chamber… • The drip chamber serves two main purposes: – – to prevent air from going into the line and to monitor fluid flow rate. • There is a line engraved into the drip • • chamber which marks the proper fluid level. If you do not put enough fluid in the chamber, e.g. if you forget to squeeze the chamber as you puncture the bag, air can get into the line and flows into the patient’s venous system. This can be very dangerous if lots of air gets infused. To correct, simply squeeze the chamber and flow out the bubbles. Too much fluid disallows you from visualizing the drip rate, which is rather annoying. To correct this, tip the bag upside down allowing air to come to the top of bag, then squeeze the chamber, allowing bubbles to backflow into the chamber. Correct Too much air! Too much fluid Fill the tubing… • Having filled the drip chamber with the appropriate • • • • • • level of fluid, allow the tubing to fill with fluid. This happens by gravity, so the bag must be above the end of the tubing, ideally hanging from the ceiling. Watch the tubing fill and ensure there are no air bubbles throughout the length of the tubing (2-3 small ones are acceptable). Continue flowing saline onto the floor until all bubbles are gone. Shut off flow using the regulator as shown. Rolling towards the bag increases flow, away from bag shuts it off. If there is NO flow, check for a clamped clamp. Many good IV’s have been unnecessarily pulled because of clamps! The regulator holder is a little appreciated feature. It can be clamped around the tubing just below the drip chamber to allow easy visibility and access…you get bonus points if you do this! Leave the end of the tubing in an easy to reach place, like hung up by the bag or behind the pillow, NOT on the floor. Clamp Regulator Regulator holder Opening the catheter package Other preparation • You have now completed the official business of ‘setting up a line.’ To put the catheter in and ‘start the line,’ you should be on top of a few things: – Get a tourniquet, gloves, alcohol preps, 2x2’s and 4x4’s ready (top drawer). – Cut five pieces of transpore tape, each about as long as your middle finger. Cut one more piece down the middle as shown. – Open an alcohol prep as shown by tearing down the middle, not where it says ‘open here.’ This makes the alcohol prep stick out and easy to grab. – Four by fours and 2x2’s can also be open by tearing down the middle. Transpore tape 4x4 Tourniquet 2x2 IV catheter Alcohol preps The way to open an alcohol prep and tear tape. Once the catheter is in… • Usually you will just need to remove • • • the cap off the end of extension set and hand the end of the tubing to the AIC. If they ask for extra assistance, this is what to do. Hold the end of the extension set as shown and insert it into the hub of the catheter. Then twist the lock onto the hub by turning clockwise. NOTE: sometimes the lock sticks, making it hard to lock onto the hub. Always loosen it by twisting it around before attempting to attach to the catheter. Open the line using the regulator. Twist to loosen Twist clockwise Taping • The catheter and tubing must now be held • Sticky down in place until secured. This is done using the tape you cut. Remember it is everyone’s job to protect the IV, so watch your step, and help the person taping. Your end result should look like this. – The first piece of tape is cut in half lengthwise and turned upside down, and forms a U around the catheter. Not all providers use this technique. – The remainder go across the catheter and 2x2. – ALWAYS fold the tubing over on itself and tape as shown to leave slack in the line. – Do your best to leave the ports accessible. • Remember that the bag of fluid must be kept above the level of the heart at all times. If you must lower the bag, eg putting it on the patient’s lap to unload the ambulance, make sure the regulator is to off, or blood will backflow into the tubing. Sticky up Towards catheter Sticky down Arm board Adjusting flow & Troubleshooting • There are two basic rates that IV fluids are run in the prehospital setting: – Slow: known as ‘KVO’ for ‘keep vein open’ or ‘TKO’ for to keep open. This is about one drop every two seconds. Adjust the regulator as you watch the drip chamber. – Fast: known as ‘wide open.’ Open the regulator all the way and allow the IV to flow at its maximal rate. • Always watch the IV site for signs of infiltration, such as pain, redness and swelling. Top ten reasons your IV is not running 1. It is not in the vein. Instead, it is in the interstitial space. This is known as infiltration. 2. The tourniquet is still on. This is very common! 3. The blood pressure cuff is still on the same arm and pumped up. 4. The bag is below the level of the heart. 5. The tubing is clamped. 6. The extension set is clamped. 7. The regulator is set to off. 8. You are standing on the tubing. 9. The cot is on the tubing. 10. The drip chamber is overfilled, so drips are not visible. Sharps • A ‘sharp’ is any sharp object (IV needle, IM • • • • • • needle, glass ampule) that may be contaminated by blood or body fluids. Extreme caution must be exercised by all members involved in patient care when a sharp is present on a scene, as an inadvertent stick may lead to transmission of infectious diseases, such as hepatitis. Place the retracted IV needle into a sharps container. Press down on the container as shown until it snaps closed. Do NOT close the container by squeezing it between your two hands, as sometimes a sharp is able to puncture the bottom of the container and can pierce your hand. There are also sharps containers on all ambulances that are easier to use (look for the big red box). In contrast to this picture, always wear gloves. Review • The steps in setting up a line include – Open the packaging for the fluid bag, tubing and extension set – Attach the tubing to the extension set – Attach the tubing to the fluid, checking for proper filling of drip chamber and absence of bubbles – Turn off the flow using the regulator – Cut tape, select catheters, open alcohol preps, etc. • Nice work! Just a few more words about some new additions to the drug box… Heparin locks • These little contraptions are also known as • • • ‘hep locks,’ since they are sometimes flushed with heparin to prevent clotting of blood in the catheter. They are used simply as an end-cap for the catheter. They obviate the need to run IV fluids to ‘keep the vein open.’ They can be punctured repeatedly as necessary to inject medications. To attach a hep lock: – Open the package shown and remove the blue protector. – Fill the port with saline to remove the air. – Connect the hep lock with the hub of the catheter and secure with tape. – Flush with saline to remove stagnant blood in the catheter. Alligator Clips • Alligator clips are used to attach • • • accessories that usually attach directly into the IV catheter into a hep lock. It contains two plastic clips which hug the hep lock and a soft needle which punctures the hep lock membrane. Begin by attaching the IV line as shown above1. Then squeeze the clips2 and push the needle through the membrane3. Secure with tape and allow the IV fluid to run in. 2 1 3 Section III - Nebulizers • Nebulizers are small containers into which we • • put drugs to be delivered to the lungs, like albuterol and atrovent. When oxygen flows through the nebulizer, it aerosolizes the drug into small particles about 2 microns in diameter, small enough to travel all the way into the patient’s lower airways. The nebulizer is connected to oxygen on one end. The other end may be connected to a piece-pipe and held by the patient, or rigged up to an NRB, allowing hands free drug delivery. Set up 1. 2. Open the packet, found in the bottom compartment of the drug box, in a sealed bag. Attached or included in it are four albuterol bullets and one atrovent bullet. There are no saline bullets in the drug box. The plastic nebulizer has two parts which screw together. They usually come put together, but always need to be tightened. NOTE – not all nebulizers in the drug box will look like this one, but the components are the same. Spare nebulizers are kept with the NRB masks on all the ambulances. Albuterol nebulizer setup Albuterol Atrovent Saline bullet More nebulizer setup… 3. 4. 5. 6. Connect one end of the oxygen tubing to the bottom of the nebulizer and the other end to an O2 source, set from 4-10 LPM; the old school states 4-6 LPM, but the aerosol is more effective when set at 8-10 LPM. The drugs for the nebulizer include albuterol ‘bullets’ (four/box) and atrovent (one/box), used for the treatment of asthma. When you open the packet, put the extra treatments in a pocket or somewhere you will not lose them. Ask the provider which drug/s they will want to give. For some patients we will start with both an albuterol and atrovent, for others we start with just albuterol. Open the bullet by twisting off the small plastic cap (insert). Turn it upside down and place the open end into the round opening of the nebulizer. It is okay if the oxygen is flowing when you do this. REMEMBER that once you do this to always keep the nebulizer upright, or you will lose all the drug into the patient’s lap, which is much less effective ☺ Assembling delivery devices Hand-held nebulizer The standard method of delivering nebulized drugs is by hand held nebulizer (HHN). The nebulizer is attached to a T-connector, which has a piecepipe which the patient holds in his mouth. The serrated tube shown serves as a reservoir for nebulized particles to buildup between breaths. • The T-connector2 has two ends, with either a bigger or smaller diameter opening, as denoted by the circles. – – – • The mouthpiece3 fits inside the large diameter end of the T-connector. The piecepipe1 fits outside the small diameter end of the T-connector. Connect the T-connector to the round top of the neb. The patient holds the entire contraption in his/her hand. It is good for claustrophobic patients who need to feel in control. 1 2 3 Assembling delivery devices Non-rebreather mask Another option is to connect the nebulizer to the mask portion of the NRB. • Simply remove the reservoir bag and tubing from a NRB by pulling them apart. This leaves the mask and strap with a hole which fits the top of the nebulizer perfectly. • This is the method of choice for patients who are very dyspneic, in whom you are doing lots of treatment and need the patient’s arms, or in small children. Section IV – Miscellaneous skills • Injectable medications – – – – – Assembling a syringe Medication vials Bristo-jet injectors Tubex injectors Glass ampules – – – Administering Nitroglycerin Applying Nitropaste Obtaining a blood sample • Other skills Syringes • All syringes are found in the top drawer, except the large 30-cc syringe in the bottom of the box. – The 1 cc and 3 cc syringes come with a needle already attached. – The 5, 10 and 30 cc syringes need to have a needle attached to them. – The lower picture is one of the new protective needles, which are being phased-in. The orange cover is simply snapped over the needle following use. They are still disposed of in sharps containers. Assembling a syringe • Start by choosing the appropriate sized syringe. • • • 2. Twist off ch 1. Pin • You can figure this out by what volume of medication you will be giving and choosing the smallest one that will fit that volume. So don’t chose a 3 cc syringe to give 40 mg of lasix, since that is 4 cc, and you would have to draw up medication twice…this is again, suboptimal. Open the package by tearing it over the end of the syringe as shown. Then pinch the protective cap while you twist the syringe off of it and pull it out of the package. This is a time-saving maneuver. Remove a needle (NOT an IV catheter) from the top drawer and open it as you did the syringe. Then twist the syringe and needle together. Medication vials • The majority of the injectable medications in • • • • • the box come packaged as vials. To prepare this for injection, it must be drawn up into a syringe. Begin by snapping off the protective cap as shown. The rubber cap this uncovers is sterile and should be maintained as such. Invert the vial, puncture the rubber cap with a syringe, inject in air approximately the volume of medication you wish to withdraw, and then withdraw the medication by pulling back on the syringe. Then remove the syringe. Hold the syringe with the needle up and expel any air you may have drawn up. NOTE – all vials and needles are considered sharps and should be disposed of the sharps container. Never throw them in the trash. Bristo-jet injectors • Bristo-jets are premade syringes filled with medication, made ready to inject with minimal preparation, often for cardiac arrest situations. We have the following drugs as bristo-jets: – – – – – – Atropine – speeds up the heart. Epinephrine 1:10,000 – constricts peripheral vessels. Lidocaine – stops abnormal rhythms. Dextrose 50% - ‘D50’ – simple sugar for diabetics. Sodium bicarbonate – a ‘base’ to treat metabolic acidosis. Calcium chloride – an ion to treat certain drug overdoses. • You may find these set-ups in a prepackaged box (D50, bicarbonate, lidocaine) or free-standing in the drawer (epinephrine, atropine). Setting up the bristo-jet 1. If the drug comes in a box, open it. Your life 2. 3. 4. will be much easier if you follow the ‘open here’ label on the box. Pick up the glass ampule with the drug in it in one hand, and a bristo-jet injector in the other. Point the yellow caps to the ceiling, and pop them off together using your thumbs. (This is a key maneuver if you want to look cool as an EMT). Screw the two ends together. Beware that the injector has two needles in it, one hidden by the yellow plastic cover; the other punctures the blue cap to the ampule. An ALS provider will remove the yellow needle cap, insert the needle into a drug port on the IV, and inject the drug. Twist clockwise Injector Tubex injectors • • • • Another way of packaging the drug is with a syringe with a needle that does not have a handle to push the drug with. You may see epinephrine and benadryl pakaged this way. The ‘syringe holder’ contains two parts which twist over one another. The ‘injector’ slides through this contraption. To prepare a medication for injection: 1. Hold the syringe holder as shown and place a tubex syringe into the hole as shown. 2. Twist the two parts of the syringe holder around each other in a clockwise fashion. 3. Then push the injector into the back of the syringe and twist it clockwise. Syringe holder Step 1 Step 2 Step 3 Glass ampules • Some drugs, such as epinephrine, come • • • packaged as glass ampules, as shown. To retrieve the medication from the bottle, you must first swirl the bottle to move the fluid stuck in the cap into the ampule. Then break the top off as shown. Always wear gloves and protect yourself using a 2x2. Break the cap away from your body. The ampule can then be turned upside down (the fluid is kept in by hydrostatic pressure). Insert a syringe and withdraw the medication by pulling on the syringe. Do NOT inject air into the ampule, or the medication will go all over the floor. Administering Nitroglycerin • Nitroglycerin is a common medication that • • • • is used to treat chest pain of suspected myocardial origin. There is a full bottle of it in the second drawer of the box; you should be familiar with it. If asked to administer a tablet, open the vial carefully, remove a tablet, and recover the vial. Place it in a location where you will not lose it, like back where you got it. Ask the patient to lift their tongue and place the tablet under the tongue as shown. They are not to be chewed. They can close their mouth after the medication has been placed. Effects include headache, hypotension, tachycardia. Always make SURE the patient has not had Viagra in the past 24 hours, which is an absolute contraindication to giving them nitroglycerin. Applying Nitropaste • Nitropaste is an alternate form of nitroglycerin • • • • • • that is applied to the skin and very quickly absorbed. It is dosed in inches. To prepare it, WEAR GLOVES. Then open the package by twisting about the precut area (insert). Apply the paste to the paper as shown. A package is a premeasured dose of 1”, so squeeze out the whole package if asked to give 1”, two packets for 2”. Apply the paste and paper to the patient’s skin. The preferred locations are the lateral aspect of the arm (less headache, no interference with the 12-lead) and the left upper chest. Always tape the paper as shown. Change your gloves following this procedure. To remove the paste, don gloves and use a 4x4 to wipe the paste from the patient’s skin. Obtaining a blood sample • This procedure is used to obtain a • • • grey topped tube filled with patient blood prior to the administration of sugar (D50) for the determination of blood glucose prior to treatment. Always attempt to obtain a sample prior to giving ‘D50.’ The vacutainer comes in a sealed package as shown (top drawer). Prepare as shown. The IV tubing is then attached to the catheter as usual and D50 administered. IV catheter Section V - Basic Drug Review In this section, we will review where in the box each of these medicines are (organized by chief complaint) and some pearls to know for each. • Asthma – – – Albuterol - Proventil Ipatropium bromide - Atrovent Methylprednisolone - Solu-Medrol – – – – – Aspirin - ASA Nitroglycerin tab - NTG Nitroglycerin paste - NTP Morphine sulfate – MSO4 Metoprolol – – Epinephrine - Epi Diphenhidramine - Benadryl – – – – – Vasopressin - Pitressin Epinephrine Atropine Lidocaine Magnesium sulfate • Anginal Chest Pain • Allergic Reaction • Cardiac Arrest • Sick Hearts – – – – Adenosine - Adenocard Atropine HCl Dopamine HCl Lasix - Furosemide – – Dextrose 50% - D50 Glucagon – – Diazepam - Valium Midazolam - Versed – – – Calcium Chloride Naloxone – Narcan Sodium bicarbonate • Diabetic Emergenies • Seizures • Other Asthma and COPD Caused by inflammation and spasm/constriction of bronchioles. • You are treating a 26 year old man with a history of asthma for an acute asthma exacerbation. Where would you find the following and how would you set it up: – Albuterol sulfate nebulizer – Atrovent nebulizer – Solu-Medrol injection • THINK before you click to the next slide. Asthma/COPD Drugs Albuterol Sulfate Dose: 2.5 mg in 3 cc bullet Action: Dilates bronchioles when inhaled. Prep: Squirt into assembled nebulizer as previously described. Cautions: Can cause tachycardia and palpitations. Ipatropium bromide (Atrovent) Bottom of Box Dose: 2.5 mg in 3 cc bullet Action: Dilates bronchioles by blocking parasympathetics. Prep: As above. Always with albuterol. Cautions: As above. Methylprednisolone (Solu-Medrol) Middle Drawer Dose: 125 mg IV (ped 1-2 mg/kg) Action: Decreases inflammation in the bronchioles, takes several hours for effect. Prep: Remove from box, then press top down as shown. This pushes stopper through and mixes the drug. Draw up with 10 cc syringe. Anginal Chest Pain Caused by excessive work-load of the heart muscle relative to oxygen delivery. In MI, this is due to a clot forming in a coronary artery. • You are treating an 85 year old man with chest pain. The medic then asks you to get him the following: – Aspirin – 4 tablets chewed – Nitroglycerin – 1 tablet sublingually – Nitropaste – 2” applied to the shoulder – Morphine - 2 mg for IV use – Metoprolol – 5 mg for IV use Where would you find these medications and what are the basic reasons we give them? Chest Pain Drugs Baby Aspirin Dose: 4 tablets, chewed Action: binds platelets and decreases clotting in a potential heart attack. Sublingual Nitroglycerin Dose: 1 tablet under the tongue, repeated Action: Dilates veins and arterioles to decrease work on the myocardium. Cautions: headache, hypotension, tachycardia. NitroPaste Middle Drawer Metoprolol Tartate Dose: 5 mg IV, repeated twice more Action: Blocks epinephrine at the Breceptor, and slows down the heart. Prep: Draw up in a 5 cc syringe. Cautions: Do NOT use in asthmatic patients. Dose: 1-2” transdermal. One packet equals 1”. Apply to the deltoid area and tape the sides. Action: same as above. Morphine Sulfate Dose: 2 mg IV Action: Binds to opioid receptors and decreases pain. Prep: Draw up with a 1 cc syringe. Some medics dilute 1:10 in a 10 cc syringe. Allergic reaction Caused by release of histamine and other factors from mast cells, which causes flushing and inflammation. A mast cell-aggravating stimulus (bee stings, food) is necessary. • You are called to treat a 3 year old who has eaten peanuts and developed hives and respiratory distress. You want to treat him with: – Epinephrine SQ (subcutaneously) – Benadryl IM (intramuscular) or IV Where do you find these life-saving drugs? – Do you remember how to get them ready? Allergic reaction drugs Epinephrine HCl Dose: 0.3 mg SQ (peds 0.01 mg/kg) Action: Binds to mast cells and inhibits the release of histamine. Also bronchodilates. Prep: Break open ampule and draw up in a 1 cc syringe. NOTE: These also come packaged as tubex syringes, so be prepared to set up whatever is in the box. Cautions: Causes tachycardia, anxiety and hypertension. Diphenhydramine (Benadryl) Middle Drawer Dose: 25-50 mg (peds 1 mg/kg) Action: Inhibits the action of released histamine on tissues, such as skin and vessels. Treats hives well. Prep: Draw up into 1 cc syringe. NOTE: These also come packaged as ampules or tubex syringes. Cautions: Can be sedating. Cardiac arrest Different from a ‘heart attack,’ this is the absence of any spontaneous heart beat or respirations. The truest of emergencies. • Cardiac arrest occurs following any number of insults, but it results in loss of peripheral vessel tone and abnormal heart rhythms. It is treated with vasopressors (vessel squeezers) and antiarrhythmics (stopping abnormal rhythms) – Vasopressors • Vasopressin • Epinephrine – Antiarrhythmics • Atropine • Lidocaine • Magnesium Sulfate • Would you know where to look for each of these drugs? How do they come packaged? Could you get them ready? Cardiac Arrest-Vasopressors Vasopressin (Pitressin) Dose: 40 Units in 2 cc IV or ET Action: Increases vascular tone and perfusion of vital organs by shunting blood centrally. Takes the place of epinephrine as a vasopressor in certain rhythms. Prep: Draw up both vials into a 3 cc syringe. Third drawer Epinephrine HCl Dose: 1 mg every 3-5 minutes (Peds 0.01 mg/kg) Action: Increases vascular tone. Can have detrimental effects on brain perfusion if high dosed. Prep: For regular strength epinephrine (1:10,000), prepare bristojet as shown to the left. For the high dose (1:1,000), draw up 1 cc per dose. Vial shown on right. Second drawer Cardiac Arrest - Antiarrhythmics Atropine Sulfate Dose: 1 mg IV (peds 0.02 mg/kg) Action: Blocks a parasympathetic receptor in the heart. This speeds up the heart rate. It is given for a slow heart rate or for asystole (no heart activity). Prep: Prepare bristojet as described before. Lidocaine Hydrochloride Bottom Drawer Dose: 1-1.5 mg/kg IV Action: Blocks sodium channels in the heart muscle and in nerves, which can get rid of abnormal heart rhythms which are conducted by heart muscle (ventricular tachycardia and fibrillation). Prep: Prepare bristojet as described before. It can also be administered as a drip. To do this, mix the entire bottle in a 250 cc bag with microdrip tubing. Cautions: Can cause hypotension and lethargy. Magnesium Sulfate Middle Drawer Dose: 2 g IV Action: Competes with calcium for calcium channels which is another way to get rid of abnormal heart rhythms. Especially good for a special form of ventricular tachycardia called torsades de pointes. Prep: Draw up both vials in a 5 cc syringe. Cautions: Can cause hypotension and lethargy. Sick Hearts This is a hodgepodge of different medications used to treat patients with various problems with their heart. • Case 1 – – You are treating a 25 year old man with a heart rate of 260 c/o palpitations. Your team decides to treat him with adenosine… • Where do you find this medicine? • What size syringe will you use to draw up this medicine? • What else will you need to prepare when giving this medicine? • Case 2 – – You are treating a 76 year old woman with congestive heart failure. In addition to nitroglycerin and morphine as described before, you might treat her with lasix or dopamine. • Where do you find these medicines? • What is special about dopamine that you should know? Sick Hearts - Case 1 Adenosine (Adenocard) Middle Drawer Dose: 6 mg, repeated with 12 mg fast IV Action: Adenosine is a natural hormone released by the body during periods of cardiac stress. It binds to the adenosine receptor and slows down the heart. It is used for patients with supraventricular tachycardia to slow down the heart. Prep: The AIC will need lots of help, since these patients are fairly sick. The drug has a half life of 6 seconds once it enters the vein, so you have to follow the bolus with about 30 cc of normal saline (drawn up from the bag into a 30 cc syringe) and pushed into a port in the tubing. -Draw up one vial of medicine in a 3 cc syringe. -Draw up 30 cc of fluid in a 30 cc syringe with a needle) -When the AIC pushes the medicine, push the ‘record’ button on the monitor so the cardiologists can see the rhythm change. Cautions: The drug causes asystole for usually about 5-10 seconds. This is very scary to the patient, and more so to the person who pushed the medicine. Be ready! Sick Hearts – Case 2 Furosemide (Lasix) Dose: 40-120 mg (peds 1 mg/kg) IV/IM Action: Causes increased urine production by decreasing resorption in the loop of Henle. Also briefly dilates vessels. Prep: Draw up one or two vials in a 10 cc syringe. There are 10 mg in each cc you draw up. Cautions: Can cause hypotension and must be administered slowly over a few minutes. Can cause ringing in ears. Dopamine (Intropin) Dose: 2-20 µg/kg/min, given as a drip Middle Drawer Action: Depends on dose: 2-5 µg/kg/min leads to dilation of renal arteries; 5-10 µg/kg/min leads to increased rate and force of contraction of the heart; 10-20 µg/kg/min leads to the above and peripheral vasoconstriction. Used anytime there is severe hypotension refractory to fluids and rate control. Prep: Draw up 200 mg of dopamine (1 vial) into a 5 cc syringe and inject it into a 250 cc D5W bag connected to a minidrip tubing. This will be attached to an injection port in a macrodrip tubing and administered as a drip. Diabetic Emergencies Altered mental status or unresponsiveness can be caused by either high or low blood sugar. • You are treating a 48 year old diabetic woman who took her usual dose of insulin today but forgot to eat breakfast. She was found unresponsive by her husband in the house. Since she is unable to eat, you decide to treat her with either IV D50% or glucagon. – Dextrose 50% • What two things do you need to set up before you get the D50 ready? Where is the D50% and how do you set it up? • – Glucagon • Where is the glucagon located? • How do you prepare it? How is it administered? Diabetic Emergencies – Dextrose 50% Dextrose 50% (‘D-50’) Dose: 25 g (Peds 0.5 mg/kg) Action: Dextrose is an isomer of glucose. When given into a vein, it raises blood sugar quickly. Bottom of Box Prep: Administration of intravenous sugar consists of three steps: • Set up a macrodrip IV with saline as the fluid. • Set up the vacutainer as described before (shown at bottom) to draw a blood sample before administration of the drug. This allows documentation of hypoglycemia. • Set up the D50 syringe. They come packaged in one of two ways. • Preassembled syringe (top picture). Just remove the grey cover and attach a 19 g needle. It is now injectable into an IV port. Top Drawer • Bristo-jet (middle picture). Set up as described before. • When given to a child, dextrose must be diluted in a 4:1 dilution in 30 cc syringe. Caution: Always watch the IV for good flow and the site for signs of infiltration, since infiltrated D50 causes death of surrounding tissues. Diabetic Emergencies - Glucagon Glucagon Dose: 1 mg (peds 1 mg) intramuscular Action: Enters the bloodstream after being absorbed from the muscle. It then enters muscle and liver where it breaks down glycogen into sugar. It usually takes about 5-10 minutes before a patient’s mental status will begin to improve if this is the problem. Middle Drawer Prep: Open the plastic bag and inject the syringe of fluid into the vial with the glucagon powder. Mix up the combination by shaking the vial. Then draw up the homogenous mixture with the syringe. It can be injected IM or IV. Cautions: None. Seizures Caused by uncontrolled discharges of neurons in the brain. • You are treating a 26 year old alcoholic man having a tonic-clonic seizure which has been persisting for the past 6 minutes. After treating with D50, you can treat the seizure with one of two drugs: – Diazepam (Valium) IV or PR (per rectum) – Midazolam (Versed) IV or IM • Where do you find these drugs and how do you • prepare them? What is their mechanism? Seizures Diazepam (Valium) Dose: 2 mg IV, 5 mg PR (peds 0.1 mg/kg) Action: Goes into the CNS and hyperpolarizes the neurons by opening a chloride channel. This stops seizure activity, which is caused by neuronal depolarization. Prep: Draw up the entire vial into a 3 cc syringe. It can then be injected IV or PR. Caution: Causes sedation following cessation of seizure activity. Basically, the patient will appear drunk, since alcohol has much the same effect as this class of drug. Middle Drawer Midazolam (Versed) Dose: 2 mg IV/IM (peds 0.1 mg/kg) Action: Same as above. Versed has a quicker onset and is therefore a nice drug to sedate a patient for cardioversion. It can also be given IM to a seizing patient. Prep: Draw up contents of one vial into a 3 cc syringe. Cautions: As above. Miscellaneous Drugs • You are treating a 17 year old boy who is unconscious. • • You suspect a narcotic overdose because of his small pupils. You decide to treat him with naloxone. You are treating a 24 year old woman for a tricyclic antidepressant overdose who is in an abnormal heart rhythm due to the drug. The AIC treats her with sodium bicarbonate. Then, the father of the above two patients got depressed and overdosed on his blood pressure medicine called verapamil, a calcium channel blocker. You decide to treat him with calcium chloride. – Where are these drugs found and how are they prepared? Miscellaneous Drugs Naloxone (Narcan) Dose: 0.8 mg (peds 0.8 mg) IV, IM or ET Action: Blocks opioid receptors and thus the effect of opiates on the CNS. Reverses narcotic coma. Middle Drawer Prep: Draw up 2 cc in a 3 cc syringe. Give slowly, titrated to respirations. Note – sometimes packaged in a vial. Sodium Bicarbonate Dose: 50 mEq (peds 1 mEq/kg) IV Base of Box Action: When given IV, it raises the pH of the blood (makes it less acidic). We do this because the heart and brain are significantly impaired in severe acidosis. You will see this given in TCA overdose, cardiac arrest or at an MVA with a trapped extremity (compartment’s syndrome). Prep: assemble bristo-jet injector. Calcium Chloride Dose: 1 gram IV Action: Raises serum calcium. This helps to overcome calcium channel blockade (CCB) and also causes vasoconstriction. You will see it given in CCB overdose. Bottom Drawer Prep: Prepare the syringe by adding a needle to it, as we did before. Section VI - Written Test 1. To which of the following 2. syringes do you need to add a needle to before using? Which of the following syringes would you use to draw up the following medications? A. 10 cc B. 5 cc C. 3 cc D. 1 cc i. Lasix ii. Benadryl iii. Valium iv. Morpine Sulfate v. Metoprolol tartate vi. Midazolam vii. Adenosine viii. Solu-Medrol 3. In which drawer will you find the following drugs? i. ii. iii. iv. v. vi. vii. viii. ix. x. xi. xii. xiii. Epinephrine 1:1,000 Atropine Adenosine Aspirin Nitro-Paste Syringes Albuterol nebulizer Epinephrine 1:10,000 Naloxone Valium Dextrose Glucagon Benadryl A. Top Drawer B. Middle Drawer C. Bottom Drawer D. Bottom of Box An AIC asks you to set up an IV line. 4. What are the different parts of an IV line? 5. Where in the box are they kept? 6. What are your default selections for each part of the line? 7. What are the steps of setting up the IV line? An AIC asks you to set up a nebulizer treatment. 8. Where is the nebulizer located? 9. Where can you find a spare nebulizer set-up? 10. To what do you set the oxygen flow for a nebulizer treatment? 11. The patient is a young child who is moving around too much 12. 13. to hold the nebulizer. What is the best way to deliver his medication to him? What two medications are usually delivered by nebulizer? Where are they found? 14. You are asked to give nitroglycerin to a patient. i. ii. Where will you give this? What should you, as part of the medical team, be watching out for in your patient? 15. You are then asked to administer aspirin to a patient. i. ii. How do you do this? How many tablets will you give them? i. ii. iii. How do you do this? Where should you place it? What additional step is necessary to ensure it will not move? 16. You are then asked to prepare 1” of nitropaste. 17. You are treating a hypoglycemic patient. What three things will you 18. 19. 20. need to prepare for the AIC to give D50? The above stated AIC was unable to attain the IV line and asks you to prepare glucagon. What steps are there in preparing glucagon? You are treating a patient with tachycardia. The AIC mentions adenosine. What three things will you need to have ready for him? What color is an 18 g IV catheter package? A 20 g? Which is bigger? Answer Key 1. 2. You will need to add a needle to the 5, 10 and 30 cc syringes. The 1 and 3 cc syringes come attached to a needle. The following syringes should be used: i. ii. iii. iv. Lasix – 10 cc syringe Benadryl – 1 cc syringe Valium – 3 cc syringe Morpine Sulfate – 1 cc syringe, though some providers will want a 10 cc syringe to dilute it 1:10. v. Metoprolol tartate – 5 cc syringe vi. Midazolam – 3 cc syringe vii. Adenosine – 3 cc syringe viii. Solu-Medrol – 10 cc syringe These sizes are shown just to emphasize that the syringe should be big enough to hold the entire dose, but not so big as to be inaccurate in delivering a small volume of concentrated medicine. You will have a better feel for these as time goes on. 3. In which drawer will you find the following drugs? i. ii. iii. iv. v. vi. vii. viii. ix. x. xi. xii. xiii. Epinephrine 1:1,000 – There are TWO places you will find this concentration (1 mg/cc) of epi. The high dose vial for cardiac arrest is in the middle drawer (B), as are the small vials used for treatment of allergic reactions. Atropine – Bottom drawer (C). Adenosine – Middle drawer (B). Aspirin – Middle drawer (B). Nitro-Paste – Middle drawer (B). Syringes – Top drawer (A). Albuterol nebulizer – Bottom of box (D). Epinephrine 1:10,000 – Bottom drawer (C). Naloxone – Middle drawer (B). Valium – Middle drawer (B). Dextrose – Bottom of Box (D). Glucagon – Middle drawer (B). Benadryl – Middle drawer (B). 4. The components of an IV line – – – – – IV fluid IV tubing Extension Set IV catheter Extras shown below (top drawer). 5. The remainder of these 6. components can be found in the bottom of the drug box. The default fluid is normal saline. The default tubing should be macrodrip tubing (10 drips/cc). An extension set should always be used. 7. Setting up the IV line • Begin by opening the IV fluid bag, the IV tubing bag and the extension set. • Remove the caps and connect the extension set to the IV tubing. • Squeeze the chamber and insert the tubing into the fluid bag, ensuring there are no bubbles in the line. • When the catheter is inserted into the vein, assist the AIC with connecting the extension set to the catheter and securing it. 8. 9. 10. 11. 12. 13. 14. The nebulizer set-up is found in the bottom of the box in a sealed plastic bag. Either inside the bag or taped to the outside you will find the albuterol and atrovent treatments. If you have to treat two patients with nebulizers, you can find a second one in compartment of the ambulance which carries the NRB’s and NC’s. Optimal drug delivery occurs at 8-10 LPM of flow. Most providers still set the regulator to 4-6 LPM, which is consistent with traditional teaching. If treating an agitated, active or young patient, the nebulized oxygen and medications are best delivered by attaching the nebulizer to a NRB mask. Albuterol and atrovent are the most common medications to be delivered by nebulizer. As noted above, the bullets can be found in or taped to the bag which carries the nebulizer. Nitroglycerin tablets are carried in the middle drawer of the box and are administered under the lifted tongue. The patient then closes the mouth, and will often feel a burning under the tongue or a headache. As part of the team, you will always need to watch out for hypotension caused by the medication. Frequent BP checks are necessary and should be done without prompting. 14. You are treating a hypoglycemic patient. What three things will 15. 16. 15. 16. 17. you need to prepare for the AIC to give D50? The above stated AIC was unable to attain the IV line and asks you to prepare glucagon. What steps are there in preparing glucagon? You are treating a patient with tachycardia. The AIC mentions adenosine. What three things will you need to have ready for him? If asked to give aspirin, give the patient FOUR tablets in his mouth to chew. They taste a bit sour. The nitropaste is found in premade packets in the middle drawer. You should apply one packet per inch you are asked to prepare to the white paper supplied with the nitropaste. The paper should then be placed on the shoulder to minimize headache and interference with EKG monitoring. The nitropaste should always be taped on both sides. Glucagon is found in the middle drawer. To mix it, inject the syringe of fluid into the powdered vial, mix it around, and then withdraw the mixture back into the syringe. 18. If you are treating a patient with D50: 1. 2. 3. You should first begin by setting up a default IV line. Then you should prepare the vacutainer (top drawer) to withdraw a blood sample prior to giving the drug. Then prepare the D50 syringe (bottom of box) by either assembling the bristojet or attaching a needle. 19. If you are treating a patient with adenosine: 1. 2. 3. 4. You should first set up an IV with default fluids and tubing. Then draw up one vial of adenosine in a 3 cc syringe. Then you should draw up 30 cc of saline from the fluid bag through the drug port into a 30 cc syringe from the bottom drawer. You get many extra points if you remember to press the ‘record’ button on the monitor when the medicine is pushed to obtain an EKG strip of the change in rhythm. 20. An 18 g catheter package is green, and is bigger than a 20 g catheter, which is packaged in a pink package. Closing notes Thank you for taking the time to go through this presentation. I am well aware that there is a ton of information here, and it is only intended as an introduction. Please do not be discouraged. You will get all of this stuff down with practice, which you should do anytime you get the chance. Also, be active in asking the questions you have to the members of your crew…they are there to help you. – Thanks also to all the supermodels who let me take pictures of their hands and faces ☺ – Thanks to Dayton Haugh for being our great leader and for his help with this. – Please email me (john k) with questions: jnk2f@virginia.edu • “Wherever you are, be all there.” -Jim Elliot