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American Center for Reproductive Medicine
ART Training Alumni 2004 - 2015
Hands on Training in Assisted Reproductive Technology
Abu Dhabi
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Kuwait
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Learn from the Leaders
The American Center for
Reproductive Medicine
Cleveland Clinic’s American Center for Reproductive
Medicine was established 23 years ago in 1993 with
a three-fold mission to: conduct cutting-edge research
into the causes of human reproductive pathologies,
develop new fertility biomarkers and treatment
modalities, and train physicians and scientists with
a commitment to advancing the understanding
of human reproduction, infertility and fertility
preservation.
About Cleveland Clinic
Cleveland Clinic is ranked as one of America’s Top 5 Hospitals by U.S.News & World
Report. Located in Cleveland, Ohio, Cleveland Clinic is a nonprofit, multispecialty
academic medical center that integrates clinical and hospital care with research and
education. Founded in 1921 by four renowned physicians with a vision of providing
outstanding patient care based upon the principles of cooperation, compassion and
innovation, it is the second largest group practice in the world with 3,262 physicians
and scientists practicing and researching in more than 130 medical specialities and
more than 1,400 beds.
In addition to the main hospital located near Cleveland’s historic University Circle, the
Cleveland Clinic operates nine regional hospitals, a children’s hospital, and 18 fullservice family health centers in Ohio, as well as hospitals in Florida, Las Vegas, Canada,
and Abu Dhabi, employing more than 43,000 individuals and providing global world
class medical care. Last year alone, 5.9 million patients from 147 countries and all 50
states received their care at the Cleveland Clinic.
Training program in Assisted Reproductive Technology (ART)
The main hospital campus, located near downtown Cleveland, occupies 167 acres and
44 buildings. It includes a hospital, an outpatient clinic, a children’s hospital, cancer
institute, eye institute, research institute, a medical school and supporting labs and
facilities. To learn more, visit www.clevelandclinic.org.
We offer a unique opportunity to learn the latest techniques in
this rapidly changing subspecialty at one of the world’s premier
ART centers:
Course Content
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World-class faculty
State-of-the-art training facilities
Personalized hands-on training
Multiple comprehensive training modules
Tremendous satisfaction rates
Trained over 160 alumni from 43 countries since 2003
Certificate of Training awarded at the end of training
This intensive, 320-hour course is available exclusively to
scientists and physicians with specific interest in gynecology,
andrology or embryology as well as other health professionals
such as embryologists, reproductive biologists and technologists.
• In vitro fertilization (IVF)
• Intracytoplasmic sperm injection (ICSI)
• Gamete cryopreservation
• Routine and advanced tests in andrology
Hands on Assisted Reproduction (IVF/ICSI) Module 5A - 5C (160 hours)
Learn basic and advanced techniques in:
IVF Techniques
• Module 5A
• ICSI: Intracytoplasmic sperm injection
• Classical IVF
• Oocyte handling and scoring
• Embryo handling and scoring
• Catheter loading for embryo transfer
• Module 5B
• Preparation of ICSI dishes
• ICSI: injection of the spermatozoon into
the oocyte
• Oocyte handling (using fresh mouse oocytes)
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MODULE 5
Module 5A:
IVF/ICSI/Micromanipulation (80 hours)
Module 5B:
ICSI/Micromanipulation (40 hours)
Module 5C:
Advanced ART Techniques (40 hours)
Module 5D*:
Customizable ART Training (40 - 320 hours)
*How Module 5D Works:
1)Candidates select a) the techniques
Laboratory Training
they wish to learn (Modules 1-8);
and b) the duration of their training
• Equipments
• Micromanipulators: components and mechanics (1- 8 weeks).
• Installing and aligning the ICSI instruments
2)Candidates consult with the Course
Director regarding their training
• Supplies & Culture Medium
needs and choices, and
• Preparation of culture medium and dishes
together, they will decide on the
for IVF/ IVF-ICSI cases
appropriate modules and duration
• Embryo culture
required by the candidate
• Extended embryo culture
3)A personalized training schedule is
Advanced ART Techniques
created specifically for the candidate
• Assisted hatching (laser and chemical [acidified Tyrode’s] method)
4)Training is provided at a pace
• Embryo biopsy (laser and chemical methods)
established by the candidate and
Pre-Implantation Genetic Diagnosis
is geared towards fulfilling the
• Blastomere biopsy:
candidates personal needs.
• Learn the setting up of the micromanipulator
• Biopsy of mouse/hamster 8-cell stage embryos
• Use of laser and acid Tyrode’s solution for zona drilling
• Blastomere and polar body aspiration and
Referral to a Human IVF Clinic may be available to
fixation techniques
select candidates looking for clinical observation.
• Cell spreading
•Logistics of running an IVF Lab
• Fixation techniques
•Observe IVF/ICSI procedures
Cryopreservation
• Embryo cryopreservation (mouse embryos)
•Vitrification
Andrology
• Sperm preparation for IVF/ICSI
•Oocyte retrieval
•Oocyte assessment
•Fertilization check
•Embryo assessment
•Intrauterine insemination
Virtual Tour of Facilities
2 | Cleveland Clinic American Center for Reproductive Medicine
Learn more about our ART Training Program
Semenology - Modules 1A (8 hours) and 1B (16 hours)
Cryopreservation - Module 4 (8 hours)
Gain proficiency in:
Learn the proper procedures for freezing human spermatozoa:
• Procedure for freezing of ejaculated human spermatozoa
• Cryopreservation of epididymal and vas deferens aspirates*
• Isolation and cryopreservation of sperm from testicular biopsy specimens*
• Protocol for cryopreservation of ovarian tissue from cancer patients*
*demonstration only
Module 1A:
• Collection and delivery of semen sample
• Routine semen analysis
• Computer assisted semen analysis (CASA)
• Review quality control method for semen analysis
• Proficiency survey for semen analysis
Module 1B:
• Name and perform sperm morphology assessments by WHO and Kruger’s strict
criteria (WHO 4th and 5th Ed.)
• Distinguish the differences between the two morphology classification systems
• Observe semen smear preparation and practice staining techniques
• Review quality control measures
Advanced Andrology Techniques - Module 2A (40 hours) and 2B (80 Hours)
Gain proficiency in these advanced techniques:
Module 2A (40 hours)
•Measurement of sperm DNA
fragmentation by TUNEL assay using
FACS* Flow Cytometry
• Measurement of Oxidation Reduction
Potential (ORP) in semen samples
• Measurement of Reactive Oxygen
Species (ROS) levels in semen samples
• Measurement of lipid peroxidation
in semen samples
• Measurement of Total Antioxidant
Capacity (TAC) in seminal plasma
• Selection of non-apoptotic spermatozoa
using MACS** technique
Module 2B (80 hours)
• Measurement of sperm DNA
fragmentation by TUNEL assay using
FACS* BD Accuri C6 Benchtop
Flow Cytometer
• Measurement of Oxidation Reduction
Potential (ORP) in semen samples
• Measurement of Reactive Oxygen
Species (ROS) levels in semen
samples
• Measurement of lipid peroxidation in
semen samples
• Measurement of Total Antioxidant
Capacity (TAC) in seminal plasma
• Selection of non-apoptotic
spermatozoa using MACS** technique
*Fluorescence-activated cell sorting
**Magnetic-activated cell sorting
ART Sperm Preparation - Module 3 (16 hours)
Develop skills in sperm preparation for ART:
• Preparation of ejaculated sperm for ART:
Sperm wash
Double density gradient technique
Swim-up protocol
• Method of retrieval of sperm from retrograde ejaculate (demonstration only)
• Sperm retrieval and preparation of testicular biopsy specimens (using rat or
mouse specimens)
Vitrification - Module 6 (8 hours)
Acquire competency and knowledge of vitrification:
• The fundamentals of vitrification
• Setting up vitrification for routine use in an embryology laboratory
• Hands on training in vitrification of oocytes and embryos using
techniques such as: open and closed vitrification system, warming of cryopreserved
oocytes and embryos, oocyte and blastocyst vitrification, cleavage stage embryo
vitrification
Management of IVF and Andrology Laboratories - Module 7 (16 hours)
Gain proficiency in:
•Implementing a Total Quality Management Program
•Regulation, licensing and accreditation
•Quality Control and Quality Assurance
•Proficiency Testing
•Quality management tools
•Troubleshooting
Preparing for CAP Accreditation and FDA Inspection - Module 8 (16 hours)
Learn how to prepare your laboratory or tissue bank for accreditation by the College
of American Pathologists (CAP) Reproductive Laboratory Inspection Program
•How to prepare for your laboratory accreditation by the College of American
Pathologists (CAP) Reproductive Laboratory Inspection Program or your tissue
banks by the United States Food and Drug Administration (FDA) inspection
(Client Depositor only).
•What to do: Pre-inspection, during inspection and post inspection
•Inspection Techniques
•Quality Management (pre-analytic, analytic and post-analytic processes)
•Critical indicators for all three processes
•Laboratory General Checklist
•Reproductive Laboratory Checklist (Embryology and Andrology)
•Team Leader assessment
•FDA Compliance
Training Faculty
Ashok Agarwal, PhD, HCLD
Director, Andrology Center
Director, American Center for
Reproductive Medicine
Professor, Lerner College of Medicine
Edmund Sabanegh, MD
Chairman, Department of Urology
Head, Section of Male Infertility
Professor, Lerner College of Medicine
Christina Anagnostopoulou, MS
Clinical Embryologist
IVF Clinic “Embryo ART”
Athens, Greece
Rakesh Sharma, PhD
Research Coordinator,
American Center for Reproductive Medicine
Associate Professor, Lerner College of Medicine
Israel Maldonado Rosas, MSc
IVF Lab Director
Mexican Institute for Advanced
Reproductive Technology (Inmater)
Mexico City, Mexico
Sajal Gupta, MS, MD, TS (ABB)
Testimonial
Testimonial
(MS in Clinical Embryology, Jones Institute)
Reproductive Specialist
Supervisor, Andrology Center
Assistant Professor, Lerner College of Medicine
Learn more about our ART Training Program
Cleveland Clinic American Center for Reproductive Medicine | 3
Training Methodology:
Scholarship in Teaching Award
Training Program in Advanced Reproductive Techniques
1.Training provided by 2 certified, practicing Clinical Embryologists
2.Trainers include Andrologists, Reproductive Endocrinologists and other
experts in ART
3.Fully hands-on, one-on-one laboratory training sessions under the direct
guidance of Clinical Embryologists
• Training is done using animal models (frozen hamster oocyte and
mouse embryos) (Module 5)
4.Each training session is customized to the trainee’s
• Professional background
• Level of skill and competence
• Specific training needs
• Desired outcomes from attending the ART training course
5.Interactive discussion and teaching sessions
6.Live lectures and multimedia presentations in small group sessions
7.Four state-of-the-art micromanipulators dedicated solely for training
purposes (IVF/ICSI)
Note:
• Training is offered in a dedicated ART training suite inside a non-clinical
research laboratory
• There is no patient contact
The Case Western Reserve School of Medicine Scholarship in Teaching Awards is an annual program
designed to recognize faculty contribution to education from the preceding year and promote
undergraduate, graduate, and continuing medical education teaching as a scholarly activity.
Cleveland Clini
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American Center for Reproductive Medicine
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Center for Reproductive Medicine
ART Training
Let it be known that
This document reflects the performance of the candidate during the
2015 ART Training Session: Module 5A (IVF/ICSI/Micromanipulation)
Shazia Magray, M.D, MRCOG
This is to attest that the trainee,
Dubai, UAE
has received
“Bindu Garg”
Hands on Training in Human Assisted Reproduction
Module 3: Sperm Prepration, Module 4: Cryopreservation,
Module 6: Vitrification and Module 5A: IVF/ICSI, Micromanipulation, for 160 hrs offered by the
American Center for Reproductive Medicine, Cleveland Clinic
has successfully completed the course work prescribed by the Cleveland Clinic’s
Center for Reproductive Medicine and is therefore recommended for the award of the
ART Training Certificate
October 5, 2015 - October 30, 2015
ASHOK AGARWAL, Ph.D.
Professor, Department of Urology
Director, American Center for Reproductive Medicine
Director, Andrology Center
Registered Trainees Will Receive…
RAKESH SHARMA, Ph.D.
Associate Professor, Department of Urology
Coordinator of Research,
American Center for Reproductive Medicine
SAJAL GUPTA, M.D.
Assistant Professor, Department of Urology
Assistant Research Coordinator
American Center for Reproductive Medicine
Grading Report
Theoretical Component (30%)
c
American Center for Reproductive Medicine
30
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Marks Obtained
Contribution (30%)
24 (80%)
24
Practical component (50%)
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Total Marks
1.Course Syllabus with Reading Material and Lab Protocols
2.Free Access to the Cleveland Clinic Alumni Library
3.Free Text Book on “Practical Manual of In Vitro Fertilization: Advanced
Methods and Novel Devices” edited by Dr. Peter Nagy et al, Springer
(only for Modules 5A-5D)
4.WHO Laboratory Manual for the Examination of Human Semen and
Sperm-Cervical Mucus Interaction. Fifth Edition (CD)
5.Certificate of Training (issued upon successful assessment by
the instructor)
6.Daily Meal Tickets
Learn More
This award was given out at the Case Medical School Education Retreat on March 12, 2015. ACRM’s
hands-on ART training program has previously been twice-recognized with this prestigious Scholarship
in Teaching Award, in 2013 and again in 2014. Besides the ART Training Program, ACRM’s Summer
Internship program has also been thrice-recognized with this prestigious Scholarship in Teaching
Award, in 2011, 2013 and 2014 respectively.
dicine
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Each Trainee is tested at the end of their training for:
1.Knowledge/Theoretical Component (30%): Multiple choice questions
on lab techniques linked to each course module
2.Practical Skills (50%): Tested on specific lab techniques taught during
the training
3.Verbal Communication & Comprehension Skills/Integrative
Component (20%):
• The performance of the candidate throughout the course will be
reflected in a Grading Report.
• Candidates who meet the training requirements and successfully
complete the course work will be awarded a Training Certificate
Teaching approaches considered scholarly are characterized by 1) purposeful planning 2) systematic
implementation and 3) reflection and assessment for improvement. The result should be an academic
product that is actively shared and that will support the development of a community of teaching
scholars.
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Trainee Evaluations:
Cl
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Let it be known that
100
Abdullah Ahmed Al Najmi, M.D.
29 (76%)
38
Integrative Component (20%)
Presentation and viva voce
FINAL GRADE
100 (20%)
20
82%
Grading Scale: A+ (>96%), A (91-95%), A- (86-90%), B+ (81-85%), B (76-80%), B- (71-75%), C (<70% is Fail)
Jazan, Saudi Arabia
has received
Hands on Training in Human Assisted Reproduction
(Module 1: Semenology; Module 2: Advanced Sperm Function Tests; Module 3: Sperm Preperation;
Module 4: Crypreservation; Module 5D: Assisted Reproduction (IVF/ICSI); Module 6: Vitrification)
for 360 hours offered by the American Center for Reproductive Medicine, Cleveland Clinic
Christina Anagnostopoulou, MSc
Trainer, ART Training
September 1 - October 28, 2015
ASHOK AGARWAL, Ph.D.
Professor, Department of Urology
Director, American Center for Reproductive Medicine
Director, Andrology Center
RAKESH SHARMA, Ph.D.
Associate Professor, Department of Urology
Coordinator of Research,
American Center for Reproductive Medicine
SAJAL GUPTA, M.D.
Assistant Professor, Department of Urology
Assistant Research Coordinator
American Center for Reproductive Medicine
Dr. Ashok Agarwal, Program Director
Israel Maldonado, MSc
Trainer, ART Training
October 12th, 2015
Date
Certificate of Training
Awarded Upon the Successful Completion
of the Hands on ART Training
For complete information, application instructions and course fees, visit www.clevelandclinic/org/reproductiveresearchcenter/arttraining.html
Virtual tour of the American Center for Reproductive Medicine
Accreditation
Accredited for 320 AMA PRA Category 1 CreditsTM
Participants claiming CME credit from this activity may submit the credit hours to
the American Osteopathic Association Council on Continuing Medical Education for
Category 2 credit.
Accredited by the American College of Embryology
ART Training Certificate Presentation Ceremony,
ACRM, September 2013
01.2016
ACRM Staff and Fellows with Dr. Joanna
Ellington, Andrology Center, March 2015
Meet Our 2015 ART Trainees
“I found the in-depth coverage of topics, customized personal
training by the outstanding teaching faculty and extensive
quality control, as the most effective aspects of this course.”
Shubhadeep Roychoudhury, PhD
Silchar, India
“The highlight of my experience would have to be receiving my
hands on andrology technique certificate - it was a lot of
work but I am proud that I was able to complete the training
requirements. I am taking away a lot from the experience.”
Rian Salasin
Pennsylvania, USA
“The hands-on part of the training
and the expert Trainers - it’s the
best training in the world and I
encourage everyone to have it”.
Osama Abdalmageed, MD
Assiut, Egypt
“We experienced a homely environment
and received unrivaled hospitality from
the Senior Staff. The course is run very
well and it meets the demands and
expectations of the candidates.”
Bindu Garg, MD, DGO, FICMCH
Gurgaon, India
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“This is the most wholesome course on
embryology that I have ever come across.
The difficult aspects like trouble-shooting
of ICSI or recent advances like vitrification
were made very clear to us. Overall, the
techniques taught here are tremendously
useful in day-to-day practice.”
Shweta Pati, MBBS
Kolhapur, India
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“I’m planning to take another course in
future to develop my skills even more.”
Ibrahim Alogaili, BSc
Amman, Jordan
Read Additional Evaluations
“The working environment was
very comfortable and the
hands-on training coupled
with the didactic lectures
were very effective.”
Jason Krumholtz, MD
Poughkeepsie, USA
Learn more about our ART Training Program
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“The most effective aspect is
having the one-on-one attention
of the ART Trainer.”
Gulfam Ahmad, PhD, MCE
Lahore, Pakistan
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“The hands-on training and
small teacher to student ratio
was good. I am the type of learner
that needs to do the task
to learn - the time for practice,
repetition, and asking questions
helped me learn the material.”
Aimee Parker, MT
Poughkeepsie, USA
“The module has the scope to give more
time in areas which the trainee finds tough,
so the course is flexible according to one’s
needs. The complete hands on experience is
like no place else.”
Priya Mehta, MBBS, DGO
Faridabad, India
“For me as a beginner, the whole course was very effective.
Techniques such as ICSI, vitrification and embryo transfer
were practiced so many times that at the end, you feel
as if you have been performing them for a long time. The
training is an amazing opportunity for those involved in the
field of reproductive medicine - A MUST DO”.
Shazia Magray, MD, MRCOG
Dubai, UAE
“I gained so much theoretical and technical know-how
from the comprehensive teaching in all the 6 modules
that I was training in. Over the 2 months, the trainers
personalized my teaching for maximum benefit and were
ever willing to patiently explain and answer my queries. ”
Abdullah Al Najmi, MD
Jazan, Saudi Arabia
Cleveland Clinic American Center for Reproductive Medicine | 5
ACRM Staff, Fellows and Students, Lerner
Research Institute, July 2013
Twelve Years of ART Training (2004 - 2015): Feedback by our ART Training Alumni
2014
Abdullahi Abdulwahab-Ahmed, MD
Sokoto State, Nigeria
“The hands-on nature
of the course made it a
standout way of learning
the techniques of ART from
experienced and seasoned Trainers and
Organizers.”
Godwin Akhabhoa, FMCOG, FWACS
Lagos, Nigeria
“The Director and other
Departmental Personnel
showed personal interest.
Excellent teachers in
a beautiful learning
environment.”
Mai Jawad Abdullah Al-Qattan, MBA
Kuwait City, Kuwait
“Learning the most recent
techniques and sharing of
different knowledge with
different co-workers was an
effective aspect of this
course.”
Zahraa Alyahaei, DPhil
Al Ain, UAE
“There was plenty of time
to practise the techniques
and discuss different
topics related to the
IVF lab with the Course
Instructors. Excellent
knowledge sharing and
transfer.”
Efiok Eyo Efiok, MBBCh, FWACS
Cross River State, Nigeria
“Excellent hands-on
training.”
Ini Jackson Etukudo, FWACS
Akwa Ibom State, Nigeria
“A theoretical background to
all the hands-on activities
are provided in lectures.
The hands-on experience is
excellent.”
Stefan du Plessis, MBA, PhD
Tygerberg, South Africa
“Experienced embryologists
provided individual training.
The ART Course was tailored
to specific needs.”
David Guerra, MD, OBGyn
Florida, USA
“Great training lab and
patient teachers. Excellent
learning material and
friendly staff.”
Sezgin Gunes, PhD
Samsun, Turkey
“The ART training was very
valuable and helpful in
learning the basics and the
latest developments in IVF
technologies and to transmit
my genetic knowledge into
reproductive medicine.”
Avraham Harlev, MD
Beer-Sheba, Israel
“The experience the Trainers
have from previous years are
reflected by their patient
teaching.”
Arun Muthuvel, MD
Chennai, India
“Each Trainee gets an
individual Trainer. The
Course was completely
custom-made, I could
choose the areas where I needed more
help. Trainers were very patient and
were willing to teach us all the time.
This is the only program that gives real
hands-on training. This program is the
best I could think of in any part of the
world. Real spoon feeding!”
Dharmaraj Palanisamy, MS, DNB
Tamil Nadu, India
“Step by step procedure in
ICSI and hands-on training
that can never be forgotten.
All teaching staff had the
patience to teach head to toe
within the stipulated period.”
6 | Cleveland Clinic American Center for Reproductive Medicine
Heidi Price, RMA
Florida, USA
“This was a very helpful
hands on training course.”
Ashlie Sadler, MA
Florida, USA
“Hands on experience and
knowledgeable teachers everything is wonderful”
Zainab Shilbayeh, MD
Texas, USA
“The way the Trainers taught
was very efficient. It was
such an excellent experience
here that I think I can’t find it
anywhere else.”
Beatriz Jimenez Vanegas, MSc
Texas, USA
“For me to switch from
animal to human ICSI was an
important step. Also the use
of vitrification, as animal IVF
uses more slow freezing. This
course is a plus for me in this
learning process and will help
me in the future for my PhD.”
Oziga Dada Vincent, MBBS, FWACS
Delta State, Nigeria
“Excellent relationship
between Trainers and
Trainees. Good practical
demonstration sessions.”
2013
Johnkennedy Anyanwu, PhD
Texas, USA, 2013
“The one-on-one training was
excellent and knowledgeable
– I never
felt hurried.”
Satya Baalasundaram, MVSc
India, 2013
“I liked the one to one,
hands on experience and
having been given more
time to learn better. Also the
lectures/presentations prior
to training were
very helpful.”
Sreedhar Kammela, MD
India, 2013
“There was strict punctuality
throughout the course. I
received a thorough update
of scientific knowledge and
an orientation to research.”
Sridevi Kammela, MD
India, 2013
“Trainers gave personalized
commitment that
benefited each candidate.
Attention was also given to
every detail.”
Krishnan Kanniah, BSc
Malaysia, 2013
“There is a systematic
training program for each
day. The review process
every morning about
what we learnt the day
before – brings about
good explanation and
discussion. Trainers were
willing to answer questions
and provide excellent
explanation.”
Rizwan Malik, MD
Indiana, USA, 2013
“Lectures are excellent
and informative. Great
course, superb experience.
Faculty and staff are very
caring. Course was very
well organized.”
Saranda Murtezaj, BSc
Kosovo, 2013
“I enjoyed the many different
ways of learning techniques
from the trainers - this is
different from what I am
used to.”
Rifat Morina, PhD
Kosovo, 2013
“The equipment and the
possibility to learn new
techniques were good. The
possibility to get answers for
every question regarding the
course was perfect.”
Read Additional Evaluations
Read Additional Evaluations
Learn more about our ART Training Program
ACRM Staff and Fellows with the ART Trainer
and Trainees, ACRM, Sept 2012
Twelve Years of ART Training (2004 - 2015): Feedback by our ART Training Alumni
2013
Lillian Parzianello, BSc
Brazil, 2013
“I had exclusive attention
from the trainers; they
were able to explain
the procedures because
they have many years of
experience in their own
labs. Training is provided
by experts in IVF/Andrology
that have published in
the best journals. It was
great to receive the best
and complete textbook on
ART, i.e. the ART-Practical
Manual of IVF.”
Kannappan Palaniappan, MD
Malaysia, 2013
“Personalized guidance
in teaching and in lab
preparation. A wellstructured course; very
comprehensive.”
Jeanne Ricci, MSc
Pennsylvania, USA, 2013
“We were taught by different
trainers and used different
types of media.”
Malathy Shanmugam, MBBS, DGO
India, 2013
“I was taught all
about the basics of
handling a microscope,
micromanipulators, laser
optical system etc. I also
learnt to do ICSI confidently.”
Mahipal Singh, PhD
Atlanta, USA, 2013
“I commend the personal
commitment of the staff
and I enjoyed the home-like
environment in the lab.”
Kristina Staab, BSc
Pennsylvania, USA, 2013
“I was able to ask questions
at any time and get
immediate feedback.”
Swetha Thumula, MD
India, 2013
“The hands on and one-toone training is unique. The
course is well organized and
caters to what you want to
learn. The feedback session
everyday is excellent and
gives you more confidence.”
2012
Liliana-Aura Chitu, PhD
Romania, 2012
“As a result of the training
provided at Cleveland Clinic,
I was able to master
the skills and achieve
dexterity in ART techniques.”
Gözde Köksal, MSc
Turkey, 2012
“Excellent training with lots
of opportunity for hands on
work.”
Reem Taha, BSc
Jordan, 2012
“The hands on experience for
me was the most effective
because it provided me with
practice and taught new
techniques that I had never
seen before.”
Sweta Tiwari, MD
India, 2012
“The one on one training for
ART was excellent. The trainer
taught the steps patiently and
provided me with complete
understanding of the
protocols.”
2011
Raffaele Dinardo
Italy, 2011
“Everything was amazing,
especially the skills and
patience of the trainers.”
Marisabel Hernandez, BSc
Venezuela, 2011
“The most effective part for
me was the hands on training.
The equipment was in perfect
condition, the lectures are in
tune with the practices and
the staff are very helpful. I
think I improved exponentially
and was able to see my own
this progress.”
Bianca Kreuscher, MS
Brazil, 2011
“The course was extremely
important, because I
learned new things that I
can use immediately. The
best of all was having the
opportunity to relate to
important people and make
new contacts. It was more
than I expected.”
Helena Malvezzi, MS
Brazil, 2011
“I learned many new things and
had the chance to meet and
work with interesting people
from all over the world.”
2010
Canan Aslan, MSc
Turkey, 2010
“Adequate hands on
practice helped me
master the techniques.”
Kelly J Porter, HTL (ASCP)
New Jersey, USA, 2010
Carolina Sellito, PhD
Italy, 2010
“I would recommend the ART
Training at the Cleveland
Clinic to anyone who is
looking to receive world
class, hands on training in
ART. The knowledge and
friendships that I have
brought back to Italy will be
of immense significance to
me for many years to come.”
2009
Christopher Danga, BS
Nigeria, 2009
“Hands on training - I was
given the opportunity to
participate in cell biopsy
and fixation, and advanced
sperm function tests everything was NEW!”
Romil Stanislavov, PhD
Bulgaria, 2009
“The presentation and
demonstration of the
methods (are) in detail.
Appropriate time (given)
for discussion and
questions.”
Gulnara Utepova, MD
Kazakhstan, 2009
“Friendly staff. New
information. Excellent
overall course
management and facility
(is) conducive to learning.”
“Overall this was a great
course with a tremendous
amount of material.
After spending a week at
Cleveland Clinic, I have a
much greater understanding
of semen analysis and feel
confident I will be able to
introduce this testing to my
facility. This week has also
given me a greater sense of
appreciation for Andrology
in general.”
Read Additional Evaluations
Learn more about our ART Training Program
Cleveland Clinic American Center for Reproductive Medicine | 7
ACRM Staff and Fellows with ART Trainer and Trainees,
Andrology Clinical Laboratory, Sept 2011
Twelve Years of ART Training (2004 - 2015): Feedback by our ART Training Alumni
2008
Lina Garcia, MTCP
Puerto Rico, 2008
“The experience was
great. Everybody was very
professional and willing to
help me at all moments.
I felt very happy about
choosing this program and
I will come back if I decide
to expand.”
Desta Gelagay, BS (ASCP)
California, USA, 2008
2006
2007
Harry Beauvais, MD
Haiti, 2007
Andrea Mustata, MD
Romania, 2007
“The accessibility of
the trainers to provide
assistance and share
their great experience
was very valuable.”
“Hands-on-training
techniques were very
well organized. Very
dedicated trainers who
were patient and helpful.
Excellent ART training.”
Chris Agboghoroma, MD
Nigeria, 2007
Amanda Setti, BS
Brazil, 2007
“Very conducive atmosphere
to learning.”
“The course has met every
expectation that I had made
for the class. The class
was a ton of fun, but very
intellectually challenging
at the same time. I was
able to learn a great deal
of information that will
help in my current job. The
experience has motivated me
to work harder.”
“I have learned everything
I wanted to mainly because
of the trainer’s knowledge
and patience in teaching.”
“I liked the collaboration of
researchers from all over
the world – it gave me the
opportunity to learn more.”
Karuna Sharma, MD
Saudi Arabia, 2006
“The faculty members are
very encouraging and they
were boosting your morale
all the time.”
Pratima Sekhar, MD
India, 2006
“It was a great experience
being in such a huge
IVF lab with the best of
the infrastructure and
technical personnel.”
2005
Troy Anhalt, BS
Wisconsin, USA, 2005
“I enjoyed my time here.
The staff were wonderful
and I am exited to take
this information back to
my lab.”
Luis A Murrain Jr, DO
New York, USA, 2008
“The one to one interaction
with the instructors allowed
the trainee to focus on
the areas they feel they
need to work on the most
while meeting the course
objectives. Helpful critique
of technique and common
pitfalls to avoid. This is an
excellent training course
for those seeking to learn
new skills or refine their
technique. The strong
emphasis on research
ensures the trainee will
be up to date on current
literature and treatment
protocol.”
Samina Naeem Khalid, MD
Pakistan, 2006
Pamela Herbst, MT
Florida, USA, 2005
“This was a refresher course
for me, so the hands on time
was very valuable.”
2004
Cleveland Clinic’s American Center for Reproductive Medicine
Hands on Training in Assisted Reproductive Technology
For more info, contact
Dr. Ashok Agarwal
Director of ART Training
agarwaa@ccf.org, +1.216.444.9485
http://www.clevelandclinic.org/reproductiveresearchcenter/artmain.html
8 | Cleveland Clinic American Center for Reproductive Medicine
Mary Robert, MBBS, MD, DGO
United Arab Emirates, 2004
“The impossible being
made possible! I benefited
immensely from the
precise manner by which
the techniques were made
simple. I am now able to
perform the technique
independently and with
confidence.”
Learn more about our ART Training Program
NEW in 2016
Other Training Modules at ACRM
Training in Scientific Writing - Module 9 (120 hours)
Develop fundamental skills set necessary for you to write high quality scientific
articles from start to completion:
• Conduct a systematic literature search and scientific review of
identified articles
• Select the relevant articles and present significant findings from these
reviewed articles
• Develop an outline of the proposed article
• Develop a strategy for scientific writing
• Edit, revise and finalize the manuscript for submission to a journal
Training in Bench Research - Module 10 (160 hours)
Develop fundamental skills necessary to conduct high quality scientific
experiments in your laboratory:
•Design and develop a bench research project
• Conduct research by application of the relevant experimental techniques
• Acquire skills necessary for data analysis
• Develop the ability to present and write the research data in a methodical,
scientifically and statistically sound manner
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Cleveland Clinic American Center
for Reproductive Medicine
2016 Summer Internship
Amer
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Gain priceless research experience under
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the guidance of world-renowned experts in
·
Be part of the
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• Acquire skills to write a scientific report based on the outcomes of the
research conducted
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June 13 to July 29, 2016
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2016
Center for Reproductive Medicine
Make this a summer to remember!
The 9th Annual Summer Mentorship Course in
“Reproductive Medicine and Research”
Josh Disbrow, MBA
CEO, Aytu BioScience Inc.
Research Fellowship in
Suresh Sikka, PhD
Professor of Urology,
Tulane University, New Orleans
The American Center for Reproductive Medicine
(ACRM) is a part of the Glickman Urological
and Kidney Institute of the Cleveland Clinic. The
Department of Urology is ranked as the No. 2 Urology
program in the nation by U.S.News & World Report.
The American Center for Reproductive Medicine
enjoys an international reputation for excellence
and innovation in human infertility research and
is dedicated to disseminating its results. Research
papers from the Center staff are selected regularly
for publication in distinguished medical journals. The
Center’s website has been ranked No. 1 for research
in reproductive medicine and andrology since 2001
by all top five international search engines, including
Google, Bing, Yahoo! and Ask.com. It has attracted
over 930,000 visitors from all over the world.
More than 515 physicians and scientists from more
than 50 countries have received their training at the
American Center for Reproductive Medicine during the
past 22 years. Nearly 140 students in majors ranging
from biology to English to the musical arts have
participated in summer internships at our Center.
Human Reproduction and Male Infertility
Faculty
Program Director
Ashok Agarwal, PhD
Professor, Lerner College
of Medicine
Director, American Center for
Reproductive Medicine
Director, Andrology Center
Department of Urology
Cleveland Clinic
Coordinators
Rakesh Sharma, PhD
Associate Professor,
Department of Urology
Research Coordinator,
American Center for
Reproductive Medicine
Cleveland Clinic
Consultants
Sajal Gupta, MD
Assistant Professor,
Department of Urology
Assistant Research
Coordinator, American Center
for Reproductive Medicine
Cleveland Clinic
Sijo Parekattil, MD
Co-Director of Personalized
Urology and Robotics Clinic
South Lake Hospital and
Orlando Health
Clermont, Florida
Botros Rizk, MD
For more information,
please
contact
For more information,
please
contact
Cleveland Clinic
American Center for Reproductive Medicine
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Email: crm@ccf.org
For more information, please contact:
Table of Contents
For additional information on internship staff, please visit our faculty page.
Mail Code X-11
10681 Carnegie Avenue
Cleveland, OH 44195, US
Phone: 216.444.9485
Fax: 216.445.6049
Scientific Presentation Day, Summer Internship 2014,
Lerner Research Institute
Professor of Ob-Gyn
Reprod Endocrinol & Infertility
University of South Alabama
Mobile, Alabama
Ce
To learn more about our Summer Internship Course, including
program faculty, internship syllabus daily schedule, complete project
listing, internship awards, pictures of interns’ presentations, reception
banquet, multimedia feedback, and accommodation options, please
visit our 2015 Summer Mentorship webpage.
The Cleveland Clinic’s American Center Center for Reproductive Medicine gives you a
unique opportunity to:
• Receive mentoring by world-renowned faculty in medicine and health sciences
• Participate in meaningful, real-time bench research experience
• Engage in intensive training in scientific writing
• Publish research articles in prestigious medical journals
• Listen to captivating lectures delivered by a team of reputed scientists and physicians
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Professor of Ob-Gyn,
Alexandria University, Egypt
Amer
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Hassan Sallam, MD, PhD
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Our Mission
Testimonials
Application
Who We Are
Books Published
Research Collaborators
Research Overview
Publications
Recent Research Alumni
Fulbright Research Scholars
About Our Center
Reproductive Research Alumni
About Cleveland
2
2-3
3
4
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5, 8, 9
6 – 14
8 – 14
15 – 16
17
18 – 19
20 – 22
23
Our Research Fellowship and training opportunities
represent one of the most active, state-of-the-art
and comprehensive programs in human reproduction
and infertility in the United States.
Our Fellows gain priceless research experience under
the strong mentorship of world-renowned experts in
reproductive medicine and biology at our Center in
the Cleveland Clinic.
Center for Reproductive Medicine and the Andrology Center
Cleveland Clinic, X-11
10681 Carnegie Avenue
Cleveland OH 44195, United States
Tel: +1.216.444.9485
Toll-Free: 1.800.CCF.CARE (ext. 4-9485)
Fax: +1.216.445.6049
Email: CRM@CCF.ORG
http://www.ClevelandClinic.org/ReproductiveResearchCenter
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Ranked One of America’s Top 5 Hospitals
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American Center for Reproductive Medicine
Alumni
Alumni
ART Training Alumni 2004 - 2015
Hands on Training in Assisted Reproductive Technology
Abu Dhabi
Austria
20
20
04
Bahrain
Eman Geneidi
Mary Roberts
06
Harjot Kaur Chahlal
Brazil
Pamela Herbst
Kosovo
Arozia Moazzam
Karuna Sharma
20
Madhu Singh
Pratima Sekhar
Sameera Madan
Samina Khalid
Xueyu Xiang
Malaysia
Aline Souza
Amanda Setti
Andreea Mustata
Mexico
China
Nigeria
Colombia
Croatia
Angelica Zuccolotto
Anwar Al Harban
Ayodele Benson
Barbara Scheetz
Bruna Barros
Carla Silva
Chris Agoboghoroma
Christina
Anagnostopoulou
Fu Nan Wang
Greece
Philippines
Gita Khanna
Harry Beauvais
Hullamani Puttapa
Luciana Lopes
Nirmala Agarwal
Pallavi Khanna
Preethi Abraham
Vaishali Kale
Wirla Munhoz
Romania
Saudi
Arabia
20
08
Guyana
Amit Gupta
Ana Paula Porto
Betty John
Carmen Mirzan
Daniel de Matos
Darlaine Dorval
Desta Gelagay
Franciele Lunardi
Hong Kong
Serbia
Slovak
Republic
India
Iraq
Pakistan
Peru
Czech
Republic
Egypt
Kuwait
Lebanon
07
Canada
Chile
Korea
20
05
Gabriela Parise
Heloisa Lavorato
Israel Maldonado
Jaime MendiolaOlivares
Jessica Torres
Kiran Bijlani
Lakshmi Prasuna
Lidia de Oliveira
Lina Garcia
South Africa
Israel
Spain
Italy
Syria
Jamaica
Japan
Jordan
Kazakhstan
Luis Murrain Jr.
Madhuma Shilahar
Nilofer Poonawala
Nitin Lad
Rizwan Malik
Shital Punjabi
Sunitha
Soundarapandian
Surveen Sindhu
Wirla Munhoz
Turkey
UAE
20
09
USA
Amanda Alvarez
Anna Frusch
Asifa Ehsani
Christopher Danga
Eva Hernandez
Gulnara Utepova
Leila Chalova
Mohamed Hajjo
Venezuela
20
10
Nataliya
Savateyeva
Rajul Tyagi
Romil Stanislavov
Sarita Oberoi
Vessela Nikolova
Aijaz Anjum
Canan Aslan
Carolina Sellitto
Janis Roman
Kelly Porter
Lisa Fradl
Marilia Pieretti
Midna Torres
Shilla Chakrabarty
Susana Cordoba
Ashish Kale
Bianca Kreuscher
Bruna Selbach
Debora Rangel
Helena Malvezzi
Laura Vellez
Marisabel
Hernandez
Moisa Pedrosa
Raffaele Dinardo
Addeli Angulski
Amani Shaman
Caroline Lapa
Damayanthi
Durairajanayagam
Gozde Koksal
20
12
Sarat Sajja
Stella Antinori
5102 - 4002
Saad Al-Dujaily
Ana Nogueira
20
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Julian Trejos
Liliana-Aura Chitu
Mariana De Mello
Reem Taha
Rogerio de Souza
Saad Alshahrani
Sweta Tiwari
Johnkennedy
Anyanwu
Kannappan
Palaniappan
Krishnan Kanniah
Kristina Staab
Lilian Parzianello
Mahipal Singh
Malathy
Shanmugam
Jeanne Ricci
Rifat Morina
Rizwan Malik
Abdullahi Ahmed
Arun Muthuvel
Heidi Price
Ini Etukudo
Mai Al-Qattan
Rian Salasin
Abdullah Najmi
Bindu Garg
Aimee Parker
Osama
Abdalmageed
Shubhadeep
Roychoudhury
2004 - 2015
INMULA GNINIART TRA
ART TRAINING ALUMNI
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Saranda Murtezaj
Satya
Baalasundaram
Sreedhar Kammela
Sridevi Kammela
Swetha Thumula
Zahraa Alyahaei
Ashlie Sadler
Beatriz Vanegas
David Guerra
Dharmaraj
Palanisamy
Efiok Efiok
Godwin Akhabhoa
20
15
Sezgin Gunes
Vincent Oziga
Zainab Shilbayeh
Avraham Harlev
Simon du Plessis
Gulfam Ahmad
Shweta Patki
Ibrahim Alogaili
Shazia Magray
Priya Mehta
Learn more about our ART Training Program
Jason Krumholtz
Cleveland Clinic American Center for Reproductive Medicine | 11
American Center for Reproductive Medicine (ACRM)
our vision
“
To be a premier center
for researchers interested
in human reproduction,
providing them
individualized mentoring
and high quality training
opportunities that lead to
technical, analytical, and
intellectual expertise in
the field.
our mission
“
our values
To conduct cutting-edge
research in human
reproduction and into the
causes of infertility,
and to train physicians
and scientists to advance
the understanding of
reproductive sciences.
”
“
”
“
We believe in integrity,
excellence, innovation,
accountability, commitment,
perseverance, teamwork
and collaboration.
”
Our Story
Founded in 1993, the ACRM offers research fellowships, hands-on training in human
assisted reproduction, and summer mentorship opportunities. We also offer diagnostic
services for male infertility and cancer patients. In the past 23 years, more than 1,000
scientists, physicians, researchers, reproductive medicine professionals and students
from all over the world have trained at our Center.
”
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The DNA strand represents the essence of the research
fellowship in human reproduction, andrology and male
infertility, offered at the ACRM since 1993. More than 500
The spermatozoa and oocyte represent the personalized,
scientists/physicians from over 50 countries have
hands-on ART training course offered annually since
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trained at the ACRM. The Center is currently focusing
2003. Candidates from more than 41 countries
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on the use of proteomics and bioinformatics to
have participated in this course.
elucidate biomarkers of male infertility.
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The microscope and a hand holding the
The open book and beaker represent the
test tube represent the routine and advanced
Summer Internship program, offered annually
tru
diagnostic testing offered to infertility patients
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since 2008. Nearly 170 interns have experienced
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at the Andrology Center and Reproductive Tissue
bench research and scientific writing under the
Bank, one of the largest state-of-the-art facilities in
personalized mentorship of scientists/physicians and
the country. Our staff has more than 3 decades of experience
reproductive biologists worldwide.
in assisting patients with male infertility.
Learn more about our ART Training Program
Cleveland Clinic’s Glickman Urological and Kidney Institute is recognized worldwide for excellence in
patient care, teaching and research. It merges Cleveland Clinic’s urology and nephrology programs. Urology
and nephrology physicians and scientists at Cleveland Clinic are recognized worldwide for excellence in
patient care, teaching and research. This year, U.S. News & World Report ranked our urology program No.
2 and our kidney disease program No. 2 in the nation.
Please visit us at: clevelandclinic.org/services/urology-kidney/about-urology-nephrology
About Cleveland Clinic
Ninety-five years ago, four physicians founded a new medical center in Cleveland. It was a nonprofit group
practice where doctors from many specialties could collaborate for efficiency and better patient care. Their
mission was “to care for the sick, investigate their problems and educate those who serve.” Located in
Cleveland, Ohio, Cleveland Clinic is a nonprofit, multispecialty academic medical center that integrates
clinical and hospital care with research and education. Today, with more than 1,400 beds on Cleveland
Clinic main campus and 4,450 beds system-wide, Cleveland Clinic is one of the largest and most
respected hospitals in the country.
Today, Cleveland Clinic is a main campus, eight community hospitals and more than 75 outpatient
locations (including 16 family health centers) in northern Ohio, and facilities in Florida, Nevada, Toronto
and Abu Dhabi. Our locations are linked by health information technology and critical care transport,
getting patients to the right facility, at the right time, for the right care. Cleveland Clinic is organized into
patient-centered institutes based on single diseases or organ systems. Each institute combines medical and
surgical services at the same location under the same leadership to improve patient care and experience.
Each institute is required to establish benchmarks and measure and improve quality. Institutes are also
required to publish annual outcomes books showing volumes, results, innovations, publications and other
information relevant to patients and referring physicians. Cleveland Clinic integrates its far-flung system
with an extensive electronic medical records system. This system includes participating community
physicians and patients, who are able to access test results and portions of their medical record remotely
via the Internet. Cleveland Clinic’s model of medicine has made it possible for us to achieve cost savings
on a vast scale over the past several years. Our mantra is “Patients First.” Our motto is “To Act as a Unit.”
Our goal is to give every patient the best outcome and experience. That’s the Cleveland Clinic way.
Visit: clevelandclinic.org
9500 Euclid Avenue, Cleveland, OH 44195
The Cleveland Clinic Foundation is an independent,
not-for-profit, multispecialty academic medical
center. It is dedicated to providing quality specialized
care and includes an outpatient clinic, a hospital
with more than 1,000 available beds, an education
division and a research institute.
Learn more about our ART Training Program
Cleveland Clinic American Center for Reproductive Medicine | 13
Cleveland — a great place to call HOME!
Cleveland is the second largest city in the state
of Ohio, after Cincinnati. Located on the southern
shores of Lake Erie, Cleveland lies at the outflow
of the Cuyahoga River into Lake Erie. The main
campus of Cleveland Clinic is situated 5 miles east
of downtown Cleveland. Case Western Reserve
University and University Hospitals are within one
mile of Cleveland Clinic. Cleveland State University
and John Carroll University are also within a short
distance of the Cleveland Clinic main campus.
Nearby the Cleveland Clinic is University Circle,
which serves as the cultural, medical and education
center of Cleveland and Northeast Ohio. Medical
research in the University Circle institutions places
Cleveland as one of the major medical research
environments in the country.
University Circle is also the home to the Cleveland
Museum of Art, the Cleveland Institute of Music, the
Cleveland Institute of Art, and the Museum of Natural
History. The Cleveland Museum of Art houses one of
the country’s most highly acclaimed art collections.
The world-famous Cleveland Orchestra, performs
regularly in the elegant Severance Hall. Playhouse
Square is the home to several large theaters that
host traveling Broadway plays and various other
performances.
Rock and Roll Hall of Fame
Browns Stadium
State Theater Playhouse Square
Beachwood Place Mall
The University Circle area is walking distance
Cuyahoga Valley National Park
Edgewater Park
from Cleveland’s historic Little Italy with its brick
streets, a quaint and charming area of intimate
Italian restaurants, antique and craft shops, and art
galleries. The Coventry Village area is close to the Clinic’s main campus and popular with its shops and restaurants.
Cleveland hosts the Rock and Roll Hall of Fame and Museum, and the Great Lakes Science Center. Outdoor enthusiasts of all ages
enjoy the ‘Emerald Necklace’, the Cleveland Metroparks network of parks that encircles the city, which offer a variety of recreational
opportunities. When it comes to professional sports, Cleveland is the proud home to the Browns football, Cavaliers basketball,
Indians baseball and Lake Erie Monsters hockey teams respectively. As the Great Lakes city on America’s North Coast, Cleveland
offers abundant lakeshore for different activities.
Cleveland and its surrounding suburbs are home to nearly 3 million residents. A vibrant and versatile metropolitan area, Cleveland
has nearly 80 residential communities. Fine residential areas are located within minutes of the Cleveland Clinic campus. Recognized
as one of the best places to live and visit, Cleveland and North-East Ohio is bustling with exciting things to do for people of all ages.
Art Museum Duck Pond in Spring
Cleveland skyline in Summer
Autumn in the Park
Lake Erie in Winter
For more information about Cleveland, visit these resources:
About Cleveland, Cleveland.com, Cleveland, The New American City, Positively Cleveland, Travel Cleveland, and Discover Ohio.
Copyright
American Center for Reproductive Medicine, Cleveland Clinic Foundation, United States of America
Editor: Ashok Agarwal l Consultant: Damayanthi Durairajanayagam l Graphic Design: Bernastine Buchanan
First Edition: Jan 15, 2016
14 | Cleveland Clinic American Center for Reproductive Medicine
Learn more about our ART Training Program