newsletter - American Society for Cell Biology
Transcription
newsletter - American Society for Cell Biology
ASCB MARCH 2014 NEWSLETTER VOLUME The ASCB in 2018 Page 3 Annual Meeting Highlights 37, 10 Young French Cell Biologists 11 Reproducibility, continued on p.17 MBoC Call for Papers in Quantitative Biology Page 36 Inside COMPASS Outreach Awards 2 Executive Director’s Column 3 DORA Panel Discussion 9 BSCB Young Cell Biologist Local Meeting Highlights 12 Upcoming Local Meetings 13 WICB Column 14 Browse MBoC Features 16 Public Policy Briefing 17 International Affairs 19 iBiology Update 21 LSE Table of Contents 23 Seen on the Cell 25 Highlights from MBoC 26 2014 Call for Nominations 27 Grants & Opportunities 28 Dicty Race 28 Meetings Calendar 29 Members in the News 29 New Members 30 Member Gifts 33 Dear Labby 34 2 ASCB Task Force to Explore Reproducibility of Scientific Data The apparent irreproducibility of some published scientific results is an issue of growing concern to industry and to the scientific community. It has begun to receive attention in the news media as well, and if one believes the popular press as much as 80% of scientific research cannot be reproduced. Is that really true? Does that apply to all research or just some areas? These are just two of the questions a task force of the ASCB’s Public Policy Committee (PPC) will attempt to answer as it conducts an in-depth analysis of the issue. If reports of widespread difficulty in reproducing published research results are true, it is a problem that could threaten the scientific enterprise and undermine the authority of the scientific community. In his charge to the task force, ASCB Executive Director Stefano Bertuzzi listed four potential causes for difficulties in reproducing results: n A hyper-competitive culture that overemphasizes results n A bias in favor of positive results Page 9 NUMBER Mark Winey Nominate a Colleague for an ASCB Award! Deadline April 1. Details on Page 27. New ASCB Program Promotes Grant Funding Success of Junior Faculty at Minority-Serving Institutions MAC Visiting Professorship Program Continues The ASCB Minorities Affairs Committee (MAC) is pleased to accept applications for its new Faculty Research and Education Development (FRED) Program, which offers mentoring to help junior faculty at minority-serving institutions (MSIs) achieve greater grant funding success. Mentorship has long been recognized as contributing to the success of young faculty, but appropriate mentors are not always available in schools that are not research intensive. To address this issue, the FRED Program, directed by Michael J. Leibowitz of the University of California, Davis, has been developed by the MAC with funding from the National Science Foundation (NSF). This program will match young faculty, primarily from MSIs, with funded mentors in related research fields at research-intensive universities for a year-long structured mentorship program. The program will focus on preparation of a national research grant application by the junior faculty member. Mentors may be nominated by the junior faculty or selected from a pool of volunteers. MAC, continued on p.8 EXECUTIVE DIRECTOR’S Column c mpass ASCB Committee for Postdocs and Students announces Outreach Awards These awards, of up to $1,000, will help ASCB members engage with local schools, science fairs, and society. Credit: Ohi labs at Vanderbilt The first application deadline is April 15, 2014 Please visit http://www.ascb.org/compass-awards/compass-outreach-awards The ASCB in 2018: Council Develops a Strategic Vision by Stefano Bertuzzi It’s a funny term, but being an ex officio member of the ASCB Council and Executive Committee is one of the most exciting aspects of my job as ASCB Executive Director. I get to work with a phenomenal group of scientific leaders who put service to our community very high on their very long to-do lists. Councilors and Executive Committee members put their valuable time where their hearts are, promoting and protecting cell biology, science advocacy, Stefano Bertuzzi training, and education. I am particularly lucky this year to be working closely with our President, Jennifer Lippincott-Schwartz. It is a great asset to have a President whose lab is within walking distance of the ASCB National Office in Bethesda! Jennifer and I take full advantage of this unique opportunity by often having lunch together at a neighborhood Italian deli. If your travels and your calendar take you through Bethesda, please check ahead and see if you can join us for lunch. It would be on us, as we would love to loop you into our conversation. We normally have fun! My role as ASCB Executive Director relies on an incredible and dedicated professional staff, without whom nothing at ASCB would happen. ASCB staff is behind our website, our daily coverage on the ASCB Post, our effective advocacy in Washington, our professional development opportunities, our publishing operation, and the unbelievably complex logistics of the ASCB Annual Meeting. It’s really the ASCB staff who keep up our reputation as the “overachiever” among scientific societies, as Past-President Don Cleveland put it. Tending a Complex Machine A complex machine like ASCB requires strong leadership and governance to ensure that it remains effective, grows, and adapts strategically to better serve the scientific community. MARCH 2014 ASCB NEWSLETTER The American Society for Cell Biology 8120 Woodmont Avenue, Suite 750 Bethesda, MD 20814-2762, USA Tel: 301-347-9300 Fax: 301-347-9310 ascbinfo@ascb.org, www.ascb.org Stefano Bertuzzi Executive Director Officers Leadership and governance are in fact the two primary mandates of the ASCB Council. The December 2013 Council meeting at the Annual Meeting in New Orleans provides good examples of how Council fulfills those obligations. Cleveland, who was at his last Council meeting as 2013 ASCB President, summarized the many activities and significant outcomes achieved during his presidency. Two key 2013 objectives had been to revamp ASCB electronic communication and to refocus on creating value for young investigators. On both fronts, we had resounding success. ASCB launched a new website and a new social media campaign. The flagship of that effort was the new ASCB Post, a news aggregator and original content source for information relevant to our science. Last month, the ASCB Post along with its blogs and the hugely popular COMPASS (Committee for Postdocs and Students) page averaged 3,347 hits per week. In today’s online “click wars,” that’s an amazing figure for a news site about cell biology. We’re still hard at work on the rest of the ASCB website, trying to finalize new pages for ASCB committees based on direct input from the committees themselves. Council strongly encouraged each committee to designate a volunteer responsible for electronic communications to look after the committee page with help from the staff liaison. The ASCB website and the new electronic platforms that it hosts are far from complete. Indeed one of the paradigms of the online communications revolution is an old one from biology—change over time through natural selection, or in this case, through ASCB member–responsive selection. A central challenge remains—attracting more traffic to the website. Historically—and this holds true for most professional societies—the Society’s Jennifer Lippincott-Schwartz President Shirley Tilghman President-Elect Don W. Cleveland Past President Thoru Pederson Treasurer Kathleen J. Green Secretary Council Sue Biggins A. Malcolm Campbell Martin Chalfie Benjamin S. Glick Daniel Kiehart Ruth Lehmann Ian Macara Laura M. Machesky Tom Misteli Jodi Nunnari Mark Peifer Claire Walczak The ASCB Newsletter is published 11 times per year by The American Society for Cell Biology. W. Mark LeaderEditor Johnny Chang Production Manager Kevin Wilson Public Policy Director John Fleischman Senior Science Writer Christina Szalinski Science Writer Thea Clarke Director, Communications and Education Advertising The deadline for advertising is the first day of the month preceding the cover date. For information contact sales@ascb.org. ASCB Newsletter ISSN 1060-8982 Volume 37, Number 2 March 2014 © 2014 The American Society for Cell Biology. Copyright to the articles is held by the author or, for staff-written articles, by the ASCB. The content of the ASCB Newsletter is available to the public under an Attribution-Noncommercial-Share Alike Unported Creative Commons License (http://creativecommons.org/licenses/ by-nc-sa/3.0). Postmaster: Send change of address to: ASCB Newsletter The American Society for Cell Biology 8120 Woodmont Avenue, Suite 750 Bethesda, MD 20814-2762, USA 3 EXECUTIVE DIRECTOR’S Column Leadership and governance are… the two primary mandates of the ASCB Council. website was used in a transactional way. Members went to the site to register for the Annual Meeting, to pay membership dues, or to get information on other internally focused activities. We now need to let people—ASCB members, those who should be ASCB members, and the public—know that www.ascb.org has much more to offer these days in terms of science news, information, and insight as well as serving as a hub for a growing online community of cell biologists. The year 2013 was also a landmark for young scientists in the ASCB community. We established COMPASS, which quickly became a force of nature within ASCB. The efforts of this exceptionally talented new committee, under the leadership of Ted Ho and Jessica Polka, have truly made a difference in ASCB activities from scientific communications, to new initiatives at the Annual Meeting, to a revived ambassador program for young scientists. In the Front Ranks on Policy Battles On the policy front, ASCB in 2013 was in the front ranks in many battles. We organized several salons/dinners to bring science journalists together with leading cell scientists and science policy leaders in Washington to increase awareness of how budgets and breakthroughs are rocking research biology. The gatherings have been very effective, often resulting in pieces in major scientific and lay publications. They have also put ASCB on the public affairs map as a source of information and an influence in the realm of federal policy and science politics. Another policy success came during the federal government shutdown last October. While the Washington establishment seemed paralyzed, the ASCB called a press conference at the National Press Club timed for the day after the announcement in Stockholm that the Nobel Prize in Physiology or Medicine had been awarded for advances in cell biology. For the “shutdown” press conference, Don Cleveland flew in from San Diego, Carol Greider drove down from Johns Hopkins, and Becky Burdine took the train from Princeton to voice their outrage at the shutdown and point out the lasting damage that it was already causing to research. On a day when the National Institutes of Health (NIH) and the rest of the federal 4 government were shut down, ASCB was pointing to the benefits of past investments in science, as witnessed by the just-announced cell biology Nobel Prizes. Meantime, labs were going into mothballs and researchers were being sent home. It was a powerful message and saw significant press pickup. Our science colleagues in the federal government were quietly grateful that ASCB was speaking out for the research community. Also on the science policy side of things, ASCB led the pack in the insurrection against the misuse of journal impact factors. ASCB spearheaded the San Francisco Declaration on Research Assessment, known by aficionados as DORA. DORA caught fire and in less than nine months acquired over 10,000 individual signatures and more than 400 organizational signatures. Council was indeed very proud to see ASCB in such a strong leadership position, and it particularly thanked Molecular Biology of the Cell Editor-in-Chief David Drubin for his leadership. ASCB also picked up the banner of scientific leadership on stem cells with the release of a very influential report by the ASCB Stem Cell Study Task Force. The group proposed scientific strategies to build on what has been learned in stem cell work to date. Coordinated by the indefatigable Larry Goldstein, the membership of the task force was a virtual who’s who in stem cell biology research. Their report was presented in a public workshop in Bethesda, MD, that was attended by several NIH program directors. As a direct result, Goldstein was invited to give a rare nonmember presentation to the Advisory Council of the National Institute of General Medical Sciences (NIGMS), the NIH institute that sees the greatest opportunities in the areas singled out by the ASCB task force. Forming Strategic Partnerships Participants at the December Council meeting also heard how ASCB is forming new strategic partnerships in the corporate world of commercial bioscience. ASCB’s central mission of serving basic science and the scientific community at large remains, but the Society needs to acknowledge that our discoveries in basic bioscience have made possible a massive expansion in bioscience entrepreneurship and the creation of a whole new biotech industry. The best example of such a partnership in 2013 was the ASCB/Beckman Coulter Kaluza Prize for outstanding research work by a graduate ASCB NEWSLETTER MARCH 2014 student. The first Kaluza Prize was awarded to Tina Han of the University of California, San Francisco, for work she did in the laboratory of Steve McKnight at the University of Texas Southwestern Medical Center. For her extraordinary work on RNA granules, Han received a $5,000 check from President Cleveland and Mario Koksch, Vice President and General Manager of Beckman Coulter’s Flow Cytometry Business Unit. A Vision for ASCB in 2018 A key component of the Council meeting was the presentation of a five-year strategic vision for ASCB. As Executive Director, this task fell on my shoulders. Before I sketch out that vision, let me say that Council was enthusiastic about both the overall plan and the opportunity to hold a high-level strategic discussion. I was particularly pleased. The quintessential role for Council is not to spend time in developing a plan nor to implement it, but rather to give New Committee Activities thoughtful high-level input. Councilors’ central At the December meeting, job is to ask tough questions, Council also heard from kick the tires, prioritize options, ASCB committee chairs, and discard those options that are [T]he Society especially about their new deemed nonessential. After such a needs to activities. On this front, discussion, implementation will be acknowledge that the Education Committee much more effective. Council asked under the leadership of for more such discussions in future our discoveries in Sue Wick proposed, and meetings, and the ex officio member basic bioscience Council approved, a new said he would be delighted to make program that will allow ASCB it happen. have made members who teach to visit The proposed vision for ASCB possible a science classrooms where in 2018 is articulated around four new evidence-based teaching massive expansion core elements: approaches are being put n The Society must truly become in bioscience into action. The Women in an expert on its members. It must entrepreneurship Cell Biology Committee, know what its members need so in close collaboration with it can modularize its offerings to and the creation the International Affairs them at the different stages of their of a whole new Committee, is planning a careers, based not on title or age session at the 2014 Annual but rather on the needs of each biotech industry. Meeting on the role of individual. In essence, the key women in science around the challenge for ASCB is to know world. The Minorities Affairs what members need and what they Committee was proud to announce a new cannot find elsewhere, and then, and only National Science Foundation grant, under then, to think of what ASCB can effectively the primary direction of Mike Leibowitz and do for them. Don Cleveland, that focuses on mentoring n The Society must ensure its financial vitality junior faculty at minority-serving institutions by identifying new sources of revenue. to help increase their success in obtaining Currently, the Society depends on three grants (see p. 1). The Public Policy Committee main, highly interdependent revenue (PPC) reported that it is tackling the scientific streams —membership dues, Annual workforce issues related to immigration Meeting revenue, and publication income. reform. PPC is also concerned that Congress We envision an ASCB that diversifies understand the importance of travel for its revenue streams by partnering with scientists to attend scientific conferences. industry and other scientific societies and In addition, PPC is forming a task force to organizations in key initiatives that will allow address the topic of data replication in science, it to best serve its members and its mission a thorny issue that has generated significant (see point 1). concern in the scientific community and in n The Society must become truly international. Congress (see p. 1). The ASCB must establish a global footprint and focus strategically on areas where cell MARCH 2014 ASCB NEWSLETTER 5 EXECUTIVE DIRECTOR’S Column biology and basic science research are growing and where new concentrations of scientists can contribute to the vitality of our organization. n The Society has to build and retain a world-class staff that can lead as well as support the strategic vision and related initiatives. These four core elements can be supported by five pillars that will translate the vision into action: n To develop a science think tank that will become an epicenter of new thought and policy for dealing with global issues in science. This think tank will provide insight, ideas, and implementation pathways to lead our field and basic bioscience forward. n To increase the value proposition for ASCB regular members. Currently, the only concrete benefits that PIs and other senior scientists draw from ASCB are discounts on Annual Meeting registration and on page charges in Molecular Biology of the Cell. We need to increase the value proposition for this important membership segment. One possibility would be to look for ways to help members with gaps in research funding to find additional resources. n To draw in scientists involved with cell biology from specialized fields. The strength of cell biology is its breadth across wide domains of science. Yet today this is also cell biology’s greatest vulnerability. Many scientists who are essentially studying cell biology outside of the field’s traditional core areas identify themselves with other communities even though their work would benefit greatly from a rich involvement with those in more traditional areas of cell biology. The introduction of the biophysical and medicine “threads” at the Annual Meeting underscored how many “non-cell biologists” are in fact practicing cell biology. Initiatives and events that extend the big tent of cell biology and draw in scientists from related disciplines would be a win–win equation. Not only would it enable those in other fields to see their work in a larger context, it would bring ASCB new blood and give current members new insights, new technologies, and new collaborators from these frontier disciplines. 6 n n To expand its global footprint. ASCB must focus on international events and activities that will expand its community, take advantage of different perspectives, and bring in strengths and traditions from world science. To place a strong focus on accelerating the careers of its members. ASCB can only thrive if its members are better off because of opportunities gained through ASCB. The intensive training course for basic scientists considering careers in industry that was put together through ASCB’s wonderful partnership with the Keck Graduate Institute and EMD Millipore is a good example of such an opportunity. The course has received an astounding number of applications. We must expand career programs along these lines into new areas of training and employment. A Welcome Message There was one more highlight of the Council meeting in New Orleans. Council was honored by the presence of Jon Lorsch, the new Director of NIGMS. Lorsch spoke to Council and later to attendees at the Annual Meeting. He highlighted his vision for NIH’s most important institute for basic science, declaring that his top priority was to sustain the payline for R01 investigator-initiated grants. (Back in Washington, Lorsch demonstrated his resolve by “sunsetting” programs such as the Protein Structure Initiative to recoup precious dollars that can be reinvested in investigator-initiated projects.) In New Orleans, our Councilors listened politely but one could almost hear the sighs of relief. After Lorsch finished, praise flowed from Council members and committee chairs alike. The ex officio thought for a moment that they might hoist the NIGMS Director onto their shoulders and carry him about the room as they cheered. Cooler heads prevailed. Instead, the December Council meeting worked through its long agenda, ending on time and bidding farewell to the outgoing Don Cleveland, and welcoming the incoming President Jennifer Lippincott-Schwartz and new President-Elect Shirley Tilghman. Rose petals were scattered before the feet of the four new Council members, Ian Macara, Tom Misteli, Jodi Nunnari, and Clare Walczak. The ex officio looks forward to working with them over the next years and is moved by their volunteering precious time to serve on Council. n ASCB NEWSLETTER MARCH 2014 ASCB Social Media better than is ever! Connect with ASCB on: facebook.com/ASCBiology @ASCBiology Search ASCB pinterest.com/ASCBiology MAC, continued from p.1 The structured mentorship program will include the following supported activities: n A Career Development Workshop that will introduce the junior faculty and mentors and focus on mentorship, grantsmanship, funding agency policies and opportunities, faculty survival skills, a mock review panel/study section, and the opportunity to interact with program officers from funding agencies. The first meeting will be July 1–2, 2014, in San Juan, Puerto Rico. n A visit by the junior faculty member to the mentor’s institution, where he or she will present a seminar. n A visit by the mentor to the MSI, including a seminar presentation and meeting with students. n A meeting of junior faculty and mentors at the ASCB Annual Meeting in December, to include review of grant proposals. In addition, a curated career resource will be developed on the ASCB website to disseminate program results, to serve as a resource for junior Visiting Professor Teresa Shakespeare and Sandra Murray, Host Scientist faculty and mentors throughout the United States, and to promote communication among FRED participants. Leibowitz will be assisted by FRED Program co-directors Franklin A. Carrero-Martínez of the University of Puerto Rico-Mayagüez and Latanya P. Hammonds-Odie of Georgia Gwinnett College. ASCB Past-President Don Cleveland is the PI on the NSF grant. Application forms are available on the ASCB website at www.ascb.org/mac-fred. The deadline is April 1, 2014. As part of the application process, junior faculty must provide a one-page summary and a page describing the specific aims of their proposed project. DORA Becomes Part of the Conversation Visiting Professorship Awards Program The ongoing ASCB MAC Visiting Professorship Awards Program supports research at primarily teaching institutions that serve minority students and scientists. The program, funded by a grant from the Minorities Access to Research Careers program of the National Institutes of Health/National Institute of General Medical Sciences, will provide research support for professors at MSIs to work in the laboratories of ASCB members for an 8- to 10-week period during the summer of 2014. Application forms are available at www.ascb. org/mac-visiting-profawards. The deadline is March 31, 2014. If you have questions about either program, please contact Deborah McCall at dmccall@ ascb.org. n —Michael J. Leibowitz, University of California, Davis, and Deborah McCall, Senior Manager, Minorities Affairs ASCB Member Benefit: One-on-One CV Review Need some help with a cover letter, CV, resume, statement of teaching philosophy, or other document for the next step in your career? Members of the ASCB are willing to help. Just fill out a short form (www.ascb.org), and we’ll put you in touch with a reviewer. Then the two of you can decide which digital collaboration tool to use (email, Google Docs, Skype, Wikispaces, etc.). You must be an ASCB member to take advantage of this service. n —Thea Clarke 8 ANNUAL MEETING Highlights ASCB NEWSLETTER MARCH 2014 Bernd Pulverer, Sandra Schmid, Yixian Zheng, and Tom Misteli participated in the DORA panel discussion. It was New Orleans this time, but one year after the ad hoc meeting that gave rise to the San Francisco Declaration on Research Assessment (DORA), a panel discussion at the 2013 ASCB Annual Meeting in the Crescent City focused on the progress made and challenges faced in the quest for rational ways to evaluate the outputs of scientific research. David Drubin, Editor-in-Chief of Molecular Biology of the Cell and moderator of this year’s panel, recalled how he and Mickey Marks, co-Editor of Traffic, had become concerned about the way journal impact factors (JIFs) were being misused as a proxy for the quality of scientific research and were unduly influencing where people submit their work. Members of the group of editors and publishers who Drubin and Marks called together in San Francisco to discuss JIFs posted DORA online (www.ascb. org/SFdeclaration.html) in May 2013. In seven months, DORA garnered signatures from more than 10,000 individuals and from hundreds of influential organizations. DORA makes the general recommendation that JIFs should not be used as a surrogate measure of the quality of individual research articles, to assess an individual scientist’s contributions, or in hiring, promotion, or funding decisions. But several panelists emphasized that changing the way research is assessed is really about changing culture. “We want to change the culture from ‘where’ to ‘what’ [is published],” said ASCB Executive Director Stefano Bertuzzi. Bernd Pulverer, Head of Scientific Publications at the European San Francisco MARCH 2014 ASCB NEWSLETTER Molecular Biology Organization, noted that there is a whole ecosystem of stakeholders involved in scientific research assessment, Declaration on Research Assessment including journals and funders, but that ultimately it is researchers themselves who do the assessing. “We all need to start with our own actions,” agreed Tom Misteli, Editor-in-Chief of the Journal of Cell Biology. JIFs have many deficiencies as a tool for research assessment, explained Mark Patterson, Executive Director of eLife. For one, since it is computed as an average of a very skewed population, a small number of articles can account for a large percent of a JIF. Moreover, the calculation is not always reproducible and the data are proprietary. Something as important, complex, and nuanced as the research assessment demands data that are openly available, Patterson said. Sandra Schmid of the University of Texas Southwestern Medical Center (UT Southwestern) lamented the time and money that researchers waste doing incremental additional experiments to satisfy editors of highimpact-factor journals. Their work could be published much more quickly elsewhere and then built on by others, said Schmid. Do metrics have any role in the assessment of research? Misteli thinks not. There are many S a n Fran cis co D��RA 9 ANNUAL MEETING Highlights metrics that could be used to assess impact, he noted, although each has flaws. It might be easy for researchers to select those that make them look best. But Yixian Zheng of the Carnegie Institution of Science noted that even a highly flawed metric like the JIF has brought a needed measure of objectivity to research assessment in China. What may be needed now, Zheng believes, are better metrics. Pulverer pointed out that nonmetric-based assessment has a high overhead; it can be hard to get reviewers to invest the time. “It’s complicated,” concluded Bertuzzi, “like science.” Schmid recounted her efforts as chair of her department at UT Southwestern to focus on research accomplishments of candidates for faculty positions. Schmid asked candidates for two-page cover letters in which they explained their most significant accomplishments as a grad student and postdoc, their long-term objectives, and what is unique about their training and abilities that will help them succeed. Only after reading the cover ANNUAL MEETING Highlights letters and letters of recommendation does she look at candidates’ CVs. Not surprisingly, Schmid said that some finalists selected through this process had published papers in highimpact-factor journals, but not all. What’s next for DORA? Certainly the number of signers and the engaged audience in New Orleans underscore that DORA has become part of the conversation about research assessment. Pulverer emphasized the importance of getting funders (who he described as at “the top of the food chain”) to adopt DORA’s recommendations. Drubin noted that what is paramount in science is the content of publications and other outputs of scientific research. He said that goals for the DORA organizers include trying to create guidelines for best practices in research assessment. n —W. Mark Leader BSCB Young Cell Biologist of the Year Finds Convivial Environment at Annual Meeting It was an honor to present my work at the 2013 ASCB Annual Meeting. I want to acknowledge the British Society for Cell Biology (BSCB) for sponsoring me to participate in the meeting as part of its Young Cell Biologist of the Year award. My first feeling upon arriving at the meeting was shock. Flying out from London on a particularly gloomy Friday morning, I found myself in New Orleans on the evening of the same day, where everything around me was animated. Everywhere I looked, there were streams of passengers coming in and out of the airport accompanied by smooth jazz music whispering from the walls. Thankfully, it was not only the airport that was so alive! The organizers brought some of this atmosphere to the Annual Meeting too, creating a very convivial environment for networking and listening to the latest scientific Andrei Luchici discoveries. One of the most transformative aspects of the meeting was the newly introduced ePoster sessions. During these sessions, participants gave short oral presentations after their posters were displayed electronically. The quality of all the work displayed was exceptional. I was especially attracted by the interdisciplinary sessions on cell–cell/cell–matrix interactions and cell migration. I hope these sessions are indeed a glimpse of what will become a central part of future scientific meetings. I was also impressed by the special attention given to graduate students, postdocs, and young researchers. The workshops on scientific writing and communication and on publishing and the open discussions on science policy were truly eye opening for someone like myself at an early stage of his research career. Unfortunately, good times rolled very fast, and before I realized it I found myself back at the airport, waiting to board my flight, listening to the same lively but now distant jazz tune. n —Andrei Luchici, University College London and King's College London Note As the BSCB Young Cell Biologist of the Year, Luchici received travel funds from the BSCB and complimentary meeting registration from the ASCB. 10 ASCB NEWSLETTER MARCH 2014 Young French Cell Biologists Gain Insights within and beyond Their Fields at the Annual Meeting I was very lucky to be granted a travel award by the French Society for Cell Biology (SBCF) to go to the 2013 ASCB Annual Meeting. There I was hoping to learn more about subjects that I am not so familiar with as well as gain new insights into areas more closely related to my PhD research, such as the actin cytoskeleton, biophysics, and cell division. Thanks to the variety of subjects at this meeting, I got to do both. And what better way to learn about new topics than to be taught by top-level scientists in the field? The 2013 meeting featured Nobel Prize in Physiology or Medicine winners James E. Rothman and Randy W. Schekman, who came to discuss their lifetimes’ findings. It was such an inspiration for young scientists to have unravelled before our eyes how science is done. Piece by piece, each of these two great Agathe Chaigne scientists shared how they discovered the mechanisms of vesicle transport in cells, something that is now considered textbook knowledge but represents years of work by dozens of researchers! Another key feature of the 2013 ASCB meeting for me was the interdisciplinary threads. I was especially happy to have a mixture of sessions on the physical biology of the cell. For example, I was very interested in biophysical approaches to mitosis. Research subjects are not so narrow anymore, and everybody benefits from conferences that look at subjects from several perspectives. I truly hope that in the future there will be more opportunities for such fascinating crosstalk. n —Agathe Chaigne, College de France The 2013 meeting in New Orleans was the second ASCB Annual Meeting I have attended as a postdoctoral fellow. There I joined a roundtable discussion chaired by Ron Vale that focused on how to improve the ways in which the output of scientific research is evaluated. This discussion was based on the set of recommendations provided in the San Francisco Declaration on Research Assessment. The participants shared personal experiences on the influence of impact factors on our career progression and ended up with proposals on how the peer-review process could be improved, which we submitted to the ASCB International Affairs Committee. For me the Annual Meeting was also a great opportunity to network and to set up new collaborations. I found the poster sessions particularly well organized; they provided enough time for Véronique Marthiens stimulating discussions with scientists from, but also beyond, my field of research. This gave me an up-to-date overview on several aspects of cell biology research. Altogether, attending the New Orleans Annual Meeting was a fruitful experience that I would recommend to every young scientist. n —Véronique Marthiens, Institut Curie Note Chaigne and Marthiens were awarded travel funds by the French Society for Cell Biology and received complimentary meeting registration from the ASCB. Mark Your Calendars for the 2014 ASCB/IFCB Meeting, December 6–10 in Philadelphia! This December, ASCB will be back in Philadelphia for a joint meeting with the International Federation for Cell Biology (IFCB)! Three threads, continued from the previous ASCB Annual Meetings, will unite programs throughout the meeting: Biophysics, Medicine, and Professional Development. Of course the core areas that have traditionally been part of the ASCB Annual Meeting will be featured as well. Philadelphia is centrally located in the East Coast research science corridor and is easily accessible by plane, train, and car. More information will be available this May! Check the ASCB Newsletter and www.ascb.org. n MARCH 2014 ASCB NEWSLETTER 11 LOCAL MEETING Highlights A Local Meeting in West Virginia ASCB Underwrites Locally Organized Sessions throughout the World The Kanawha River cuts through Charleston, WV, on its way north to join the Ohio. On one brilliant October morning, the sun was quickly burning off the fog filling the river bottoms and setting the golden dome on the state capitol ablaze. It was the perfect fall Saturday for tossing a football or raking leaves. And yet 70 grad students, postdocs, and biology faculty turned up at the West Virginia University (WVU) Robert C. Byrd Health Sciences Center to hear and talk about cell biology. Galactosyltransferases in Arabidopsis, focal adhesion kinases, myosin II isoforms, and cardiac calcium channel expression in mice with disrupted genes for heart-specific growth hormone receptor were some of the topics on poster easels at the second Appalachian Regional Cell Conference (ARCC). Organized by grad students and postdocs from four regional universities, ARCC was supported by a local meeting grant from the ASCB. ARCC was one of 18 local meetings partly underwritten in 2013 by ASCB, including 11 in the United States, four in Canada, and one each in South Korea, Jamaica, and India. Charleston was picked as a central location for the four institutions taking part in ARCC. There is no basic research facility here at Byrd 12 Center, which is run by WVU as an adjunct to the local hospital. The main WVU campus is 159 miles away to the northeast in Morgantown. Marshall University is 52 miles northwest in Huntington, WV. Athens, home of Ohio University (OU), is 93 miles north across the Ohio River, while the University of Kentucky (UK) in Lexington is the farthest away, 177 miles to the west. Before ARCC, everyone agrees, the four institutions seemed to have little in common but geography. This was ARCC’s second outing. It got its start last year when ASCB member and WVU biochemist William Wonderlin spotted the call for local meeting proposals in the ASCB Newsletter. He convinced grad student Danielle Shepherd to volunteer for the role of chief organizer, and she reached out to grad students at OU and Marshall. This year it was OU’s turn to apply for the ASCB grant, make location arrangements, and line up a keynote speaker. ASCB member Maria Muccioli was the main organizer at OU, and she worked with coorganizers ASCB member Bridget Hindman at WVU and Miranda Carper at Marshall. For the first time this year, UK sent a contingent, led by ASCB member and postdoc Aaron K. Holley. Local meetings reflect local needs, and ARCC is as much about regional connections as it is about cell biology. Before the ARCC meetings, basic research students and faculty were isolated on their own campuses, the organizers say. For many of the grad students, the ARCC was the first time they had ever presented their work outside a home campus “research day.” Many spoke of the experience as a warm-up for a national meeting. ARCC kicked off in the cavernous Byrd Center Auditorium, with four grad students braving the perils of PowerPoint and the ASCB NEWSLETTER MARCH 2014 pressure of having strangers from other schools pay very close attention to their talks. Then there were questions. Afterwards, John J. Kopchick, a molecular biologist at OU, followed up with a keynote that retold the inspirational story of how his basic science discovery—the isolation of a classic antagonist of the human growth hormone receptor—made it through the translational jungle of clinical trials, patent law, and commercial licensing to become pegvisomant (Somavert), a highly effective treatment for the genetic growth disorder acromegaly. Then came the buffet lunch on paper plates outside the fourth-floor conference room that would serve as the poster hall. As lunch wound down, there was the last-minute straightening of sagging posters and the issuing of clipboards to the visiting PIs who would pick the top two posters in each of the four categories. The first group of presenters took up their positions, and within minutes the room was throbbing with the unmistakable sound of poster alley buzz— questions vs. answers, hypothesis vs. data. That day it was in West Virginia. In subsequent weeks and months, ASCB local meetings will take place from Baltimore to Glasgow to Bayamon, Puerto Rico. Even in the age of global information, the process of science is local. n —John Fleischman Upcoming Local Meetings ASCB is pleased to provide funds for young scientists (graduate students and postdocs) to organize one-day local meetings. Such meetings involve two or more institutions (within the United States or international), and topics can range from basic science to career development as long as there is clear relevance to the broadly defined field of cell biology. The next deadline to apply for funds is April 1, 2014. Applicants must be or become members of the ASCB. For more information visit www.ascb.org and click on “Meetings.” Navigating Lipid Research in Baltimore: Cell to System Carnegie Institution for Science (Baltimore, MD) April 11, 2014 Visualizing Cancer: Microscopy and Beyond CR-UK Beatson Institute (Glasglow, United Kingdom) September 2014 Cell Biology across the Bay Santa Clara University (Santa Clara, CA) May 3, 2014 Triangle Cytoskeleton Dynamics and Regulation Meeting The Research Triangle Park (Durham, NC) September 2014 Three-Dimensional Cell Cultures Center of Microelectronics in Provence (Gardanne, France) July 25, 2014 First Puerto Rico Cancer Research Meeting Universidad Central del Caribe (Bayamon, Puerto Rico) October 3, 2014 Are You Getting ASCB Pathways? You should now be regularly receiving our monthly email update, ASCB Pathways—alerting you to the latest ASCB happenings and Annual Meeting updates. If you aren’t seeing the e-newsletter in your inbox, please check your spam filter, and/or contact your system administrator to whitelist *ascb.org. n Got Questions? Labby has answers. ASCB’s popular columnist will select career-related questions for publication and thoughtful response in the ASCB Newsletter. Confidentiality guaranteed if requested. Write us at labby@ascb.org. n MARCH 2014 ASCB NEWSLETTER 13 WOMEN in Cell Biology Understand What They Want The Job Interview: Understanding Its Rules and Roles Car eer A d vi c e f o r Wo m e n a n d M e n 14 Interviews are a matchmaking process in which Understand What You Want both the interviewer and the applicant assess Before the interview, candidates should be whether the applicant is a good “fit” for the able to enumerate the characteristics of their job in question. During the earliest stages ideal job, which obviously depend upon the of filling a position, potential employers use nature of the position. Postdoctoral candidates written applications to select candidates who are typically motivated to study a particular have, at least on paper, the necessary skills and problem or to learn techniques that they can training. The purpose of interviews is typically use as they become independent to rank the candidates who investigators. People pursuing their have these characteristics in first tenure-track position are usually terms of their suitability to looking for resources to establish the particular task and to the themselves, and they probably have work environment. Often the ideas about the optimal balance final choice of one candidate between research, teaching, and other over another comes down duties. Defining these ideal traits to things that cannot easily is clearly helpful not only because be represented on a written candidates should use them to guide application—motivation, discussion, but also because potential creativity, personality—and a employers will almost always ask good interview will focus on about the candidate’s goals as a way Mary Dasso these attributes. of understanding whether his or her As in any matchmaking goals are in sync with those of the group or endeavor, the road to post-interview happiness department. can be a bumpy one. Good communication An equally large number of intangibles need during the process allows each party to to be considered during an interview. These understand the needs, expectations, and factors are no less important and can frequently perspective of the other. Things become make the difference between a job that’s a joy awkward if one party has not and one that’s dreadful. You should defined its own goals or is think about the kind of work insensitive to the requirements Before the environment that you enjoy— of the other. At the 2013 ASCB intense versus laid back, solitary interview, Annual Meeting, the WICB versus closely collaborative, and candidates Mentoring Theater presentation so forth. Postdoctoral candidates “Interviewing: The Good, The should particularly decide what should be Bad, and The Ugly” highlighted kind of interactions they prefer able to some potential interview pitfalls with their supervisor. During the through skits and discussion, interview, it is possible to draw enumerate the while offering ideas for how out information regarding the characteristics to smooth the interview environment with relatively openexperience. This article describes of their ideal ended questions. For example: some of those ideas, with a “What is your style as a supervisor, job…. few additional pointers for and how frequently do you candidates seeking postdoctoral expect to meet with each of your or tenure-track positions. I also postdocs?” or “How are interactions facilitated recommend a number of other sources where between different members of the department?” job candidates can obtain more detailed advice The answers should help to assess whether the regarding interview strategies.1–5 particulars of the job align well with your own values and preferences. ASCB NEWSLETTER MARCH 2014 The chance to choose the people on the Be prepared to discuss how you could contribute schedule is a huge opportunity and should not be missed if you are asked for input. For to the group or department that would hire example, you should always ask to speak with you. As a postdoctoral candidate, you should people who currently occupy positions similar have a working knowledge of articles from the to the one that you would fill (e.g., other host laboratory and major landmarks within its field, and you should note important projects to postdocs in the same lab, or junior faculty in the same department). These are the best which you could contribute. people to talk with about the pros and cons As a tenure-track candidate, you should of that position. Similarly, you should always use departmental websites to understand ask to speak with people whose interests might the institution that you would join, and you align with yours, either as collaborators or should tailor your presentations and approach senior colleagues, since they can to meet the needs of the provide important support, as position. For example, your discussed above. Be aware that talk should highlight not The chance to all discussions throughout the just your achievements but choose the people day are “on the record,” from the also the thought processes breakfast meeting to dinner with and technical skills that you on the [interview] members of the department. All would bring. For positions schedule is a comments will likely be reported with a teaching component, back to the search committee as huge opportunity you should be ready to discuss they evaluate your characteristics extensively your teaching and should not be 4,5 as a potential colleague.3 experience and philosophy. missed if you are The interview process should Finally, you should be aware be purely professional, and of investigators at the hiring asked for input. interviewers are not legally institution whose work may allowed to ask questions about benefit from a new colleague your personal life (e.g., about with your background. It your partner/spouse, kids, health, religion, is certainly worth the effort to seek out such individuals, since they can provide an important etc.). Discussion after the WICB Theater gave ample evidence, however, that they source of support for both your application and nevertheless broach personal topics frequently. for the initial stages of your work as a junior In some cases, the interviewer might genuinely investigator. wish to be helpful, e.g., by highlighting opportunities for spousal accommodation or Understand the Process childcare, but such a discussion may put you The person who is overseeing the interview, a in an uncomfortable position. While you are potential supervisor or the head of the search not obligated to answer, you should certainly committee, will usually provide a schedule for anticipate such questions and think about your visit. You can and should ask questions potential responses in advance, to avoid being if any part of the agenda is unclear, regarding blindsided and to have a strategy for gracefully the format of your presentation, for example, moving the interview back to more appropriate or whether it is for a general audience or for professional topics. specialists. The schedule will typically provide names of people with whom you will be talking. You should obtain at least a cursory knowledge of those people and their work, especially those who are members of the search committee. (You can even prime your memory with their faces and names by looking at their websites.) This preparation not only facilitates rewarding discussions but also avoids awkward situations, such as failing to attribute key discoveries to people close at hand or giving a superficial explanation of some phenomenon to an acknowledged expert on that topic. MARCH 2014 ASCB NEWSLETTER Optimize Your Chalk Talk Chalk talks are notoriously difficult, and there is no single format used by every search committee. However, you can do several things to optimize your performance within a chalk talk. First, clarify in advance with the search committee chair about the chalk talk format and the expectations of the committee (e.g., do they want a PowerPoint presentation or will it be “chalk” on a board? Are there particular points that should be covered?). Prepare and practice accordingly. 15 Second, unless otherwise instructed, plan to Ultimately, a successful interview will assure discuss roughly three specific aims that could not only a match and a honeymoon, but also realistically be achieved within four to six years be the basis for a long and productive working or within the scope of your first R01 grant. relationship. n You should include not only the —Mary Dasso technical details of each aim, but References also alternative approaches and 1 UCSF Office of Career and Professional how the aims work synergistically Development (2013). Interviewing for [P]lan to discuss academic jobs. https://career.ucsf.edu/ toward larger, long-term goals. Frame your proposal within a grad-students-postdocs/career-planning/ roughly three academic-jobs/interviewing. major biological question, so that specific aims 2 it becomes clear how you will Howard Hughes Medical Institute, Burroughs Wellcome Fund (2006). make significant contributions to that could Making the Right Moves: A Practical the field. realistically be Guide to Scientific Management for Finally, be conscious of Postdocs and New Faculty, Second achieved within how you guide the discussion Edition. www.hhmi.org/educationaland avoid getting frustrated or four to six years materials/lab-management/for-earlysidetracked: answer questions career-scientists. or within the from the committee completely 3 Spiliotis ET, Kwiatkowski AV (2013). and cheerfully, but quickly return The search for a faculty job revisited scope of your the focus to your own proposal with the benefit of hindsight. ASCB first R01 grant. Newsletter 36(6), 12–13. and research interests. Interplay 4 with the committee during your Wolyniak MJ, Roecklein-Canfield JA chalk talk is often used to assess (2014). Packaging yourself as a teacher. ASCB Newsletter 37(1), 12–13. whether you are enthusiastic, 5 think clearly, and can deal with unexpected American Society for Cell Biology (1996). How to Get challenges without losing your cool. a Research Job in Academia and Industry. www.ascb.org/ newsfiles/research.pdf. Interviewing provides a critical opportunity for candidates to present themselves and to learn more about the opportunities that a particular position may offer, and it is well worth a significant amount of careful preparation. Browse MBoC Features Reproducibility, continued from p.1 n Limited space in journals for describing methods n Poor training of scientists in statistics and experiment design The task force, led by Public Policy Committee member Mark Winey, together with Public Policy Director Kevin Wilson, will provide recommendations and propose initiatives to enhance rigor in conducting basic research. The task force is also being asked to examine what the ASCB can do as a publisher to improve transparency and accountability of the findings published in its scholarly journals. Winey will be joined by other members of the PPC, including chair Connie Lee, Bertuzzi, Carol Greider, Doug Koshland, and Paul Mungai. The task force is expected to ask experts to join or consult with it. n —Kevin M. Wilson Science Champion Calls It Quits Rush Holt There is more to Molecular Biology of the Cell (MBoC) than just reports of important research findings. MBoC also offers compelling, provocative, and downright helpful Features articles: Perspectives on science, policy, and careers; ASCB Awards Essays; ASCB Meeting Highlights; and much more. Now you can easily browse the Features Collection from a new drop-down menu at the top of each page. Or if you prefer you can use the static list of types of Features located on the lower right side of each page. Either way, visit www.molbiolcell.org and check out this rich source of ideas, insights, recollections, and advice. n 16 PUBLIC POLICY Briefing ASCB NEWSLETTER MARCH 2014 Physicist-turned-Congressman Rush Holt (DNJ) has decided not to run for re-election in 2014. Holt is one of 34 members of the House of Representatives who have so far decided not to run for another term of office. During his eight terms in office, Holt, a physicist by training, has become a leading advocate for scientific research in Congress. His support for science is not limited to the physical sciences, however. For many years, he has served as a co-chair of the Congressional Biomedical Research Caucus (CBRC), a nonpartisan group of members of Congress whose aim is to highlight the advances being made in biomedical research. The CBRC is operated by the Coalition for the Life Sciences, which the ASCB founded and of which it remains a member. Holt has been a regular and vocal MARCH 2014 ASCB NEWSLETTER participant in the caucus presentations. Holt may be more popularly known as a five-time Jeopardy winner who went on to beat Watson, an IBM computer matched against several members of the House of Representatives during a celebrity edition of the show. Although he did not cite a reason for his decision to retire, Holt did say in an email, “There is no hidden motive for my decision. As friends who have worked with me know, I have never thought that the primary purpose of my work was re-election and I have never intended to make service in the House my entire career. For a variety of reasons, personal and professional, all of them positive and optimistic, the end of this year seems to me to be the right time to step aside and ask the voters to select the next representative.” n —Kevin M. Wilson 17 INTERNATIONAL Affairs 2013 will always be known as the year of sequestration. The inability of Congress to do its job resulted in almost $2 billion in combined cuts to the budgets of the National Institutes of Health (NIH) and the National Science Foundation (NSF). A 16-day shutdown of the federal government, and the bad press it generated for Congress, forced Congress to do something it had not done in several years—pass a budget for the federal government. That FY14 budget included a $1 billion budget increase for the NIH and an almost $300 million increase for the NSF. With a limited amount of money for Congress to spend, both increases were respectable steps toward undoing sequestration. So when President Obama released his FY15 budget request in early March, it felt like we were taking a giant step backwards. The proposed budget includes modest 1% increases for both the NIH and the NSF. But the real steps forward for research that those increases would enable, including 650 new grants for the NIH and over 1,000 NSF grants highlighted by the President and his advisors, are not part of the FY15 budget. Instead, they are part of the Opportunity, Growth, and Security Initiative, a $56 billion program that is highly unlikely to be passed by Congress. Attention now turns to Congress, which typically like to rework the President’s budget, reminding him that Congress holds the purse strings. n —Kevin M. Wilson nationa r e t fai l Af rs Science on the Banks of the Nile: Cell Biology in Sudan President Proposes Limited Increases for NIH, NSF In PUBLIC POLICY Briefing Job hunting? Hiring? Job Hunting?Job Hiring? hunting? Hiring? Job hunting? Hiring? Find the perfect match at… Find the perfect match at cellbiologyjobs.org from ASCB The science of life, the life of science 18 The University of Khartoum is the leader in scientific research and postgraduate training in Sudan. This single university comprises 21 colleges located on four campuses with 1,300 academic staff members, who received training from all over the world. The Central Campus is located along the Nile in central Khartoum *ASCB members receive a 50% discount when posting jobs. Find the perfect match at… cellbiologyJobs.org from ASCB Sudan, officially the Republic of the Sudan, is a large and diverse country. Its capital city, Khartoum, lies where the White Nile from Kenya joins the Blue Nile from Ethiopia to form the Nile. Ancient Sudan was the first region of the world to domesticate sorghum and to cast gold and iron. Sudan’s current policies focus on strengthening higher education and basic research with the aim of training its people and developing its economy. Traditionally, Sudan has invested in free education from elementary school to university, but recently lack of sufficient funding has tended to lower the quality of higher education. In this article, we focus on the University of Khartoum, the oldest, largest, and most prestigious university in the country, and talk about cell biology research in the Department of Botany. The University of Khartoum and Scientific Research cellbiologyJobs.org THE AMERICAN SOCIETY FOR CELL BIOLOGY University of Khartoum botany students on a field trip to the Red Sea Hills in eastern Sudan Find the perfect match at… cellbiologyJobs.org MARCH 2014 ASCB NEWSLETTER ASCB NEWSLETTER MARCH 2014 from ASCB and is one of the most beautiful campuses in the world. The other campuses include the Medical and Health Sciences Campus in downtown Khartoum, the Shambat Campus (agriculture, veterinary medicine, forestry, and animal production), and the Education Campus. The University of Khartoum also includes 14 interdisciplinary institutes and centers. This large public university conducts basic and applied research. More than 2,000 postgraduate students are currently registered and are pursuing PhDs (155), masters degrees (1,611), and postgraduate diplomas (412) in basic and applied sciences, art, and social sciences. The faculties and institutions of the University of Khartoum are keen to establish links with corresponding faculties and institutions around the world. Currently 166 scientific agreements and memoranda of understanding exist between institutions in Sudan and those in 63 countries and six international organizations, but most of these agreements are inactive for political or logistical reasons. The University of Khartoum is seeking to revive these agreements or to generate new ones to facilitate a wide range of joint international projects and foster multilateral professional contacts. 19 Cell Biology in the Department of Botany The Faculty of Science is the leading research center in Sudan. This Faculty comprises five Departments (Botany, Chemistry, Geology, Physics, and Zoology). Cell biology is now housed in the Departments of Botany and Zoology. Historically, the Department of Botany was the first to include cell biology in its curriculum. This is the strongest botany department among Sudan’s universities, with 26 full-time PhD faculty members and other supporting staff for instruction and research. The missions of the department are to promote basic and applied research, to publish in the world’s peer-reviewed journals, and to generate patents for industry. Three specialized units include the Molecular and Cell Biology Lab, Plant Tissue Culture and Genetic Transformation Lab, and Phytoand Biochemistry Lab. Although sometimes inadequately equipped, these laboratories support excellent research in molecular biology, plant transformation, cell biology, microbial biotechnology, natural products, and drug discovery. With the ultimate goals of developing effective agricultural tools to improve the yield, quality, and utilization of Sudan’s rich natural flora, the Department of Botany undertakes cell biological research on cereal and vegetable crops of economic importance as well as medicinal plants. Marker-assisted selection (MAS) is applied to desirable characteristics such as tolerance to biotic and abiotic stresses. As a result, we will be releasing, in collaboration with Agricultural Research Corporation, our new cultivar of Strigaresistant sorghum (Sorghum bicolor L.) lines, which will be cultivated in the next season on millions of hectares of irrigated and rain-fed land. Similarly we produce transgenic crops like Bt cotton, droughttolerant wheat, drought-tolerant sunflower, and fungus-resistant tomato. Two years ago, we developed a transgenic tomato expressing the defensin (antifungal) gene. Currently the group is using MAS to develop white-seeded sesame lines, a characteristic highly desired in industry. We are also assessing genetic diversity in our local wheat, sorghum, onion, and sesame lines to invigorate national breeding programs. Our Microbiology Lab is exploring exploitation of microorganisms as bioreactors for the production of biofertilizers, citric acid, bioethanol, xanthan gum, and alginate. Other research projects include the use of microorganisms for bioremediation of pesticide-polluted soils and for gold and copper bioleaching from low-quality ores found in many areas in Sudan. We are also engaged in drug discovery from natural products, an area of national and international research interest. Our goal is to identify and discover bioactive compounds from traditional Sudanese medicinal plants (e.g., Hydnora johannis, Aloe sinkatana, Geigeria alat, and Citrullus lanatus) and from microbes (e.g., Streptomyces spp.). Research projects in this area focus on screening for bioactivity of secondary metabolites as antimicrobial, anticancer, anti-inflammatory, and antioxidant agents. Projects aiming at development of methods for bioremediation for petroleum hydrocarbons and toxic industrial wastes by means of enzymatic degradation are also ongoing. These ambitious programs can benefit from collaborations with research groups around the world, including the United States. Plans for a new life sciences building that will house proposed departments in Genetics and Cellular Biology, Microbiology and Parasitology, and Environmental Studies are ongoing. It is our hope that avenues for international cooperation will soon generate mutual benefits. n —Adil Ali El Hussein, Marmar A/Rahman El Siddig, Sakina M.A. Yagi, and A/Azim Ali Ahmed, University of Khartoum iBiology UPDATE iBiology Hangouts: Live Q&A Sessions with Scientists Most of our learning experiences come from trying something and not being completely successful, and then learning from that how to do better the next time. —Bruce Alberts, iBiology Live Q&A, February 7, 2014 One of iBiology’s missions is to provide access to leaders in the field of biology. Last November, the project started hosting Live Question and Answer (Q&A) sessions with scientists on topics related to iBiology talks they have recorded. Anyone with Internet access and a computer can ask questions of the speaker, watch the live broadcast, or later view a recording on the iBiology site. In February, iBiology held a Live Q&A with Bruce Alberts entitled the “Future Challenges for Science and Science Education,” which followed up on his iBioMagazine talk “Learning from Failure.” “My talk on the importance of failure really stresses the fact that we all have to learn throughout life how to deal with the incredible complexities of the real world,” said Alberts in response to a viewer’s question. Alberts, who is the former Editor-in-Chief of Science, also discussed issues with traditional teaching approaches, which typically promote passive memorization of science facts over active learning and problem solving. In his Live Q&A, Alberts urged the scientific community to get involved at all levels of the education system to help bring research experiences into the classroom. The iBiology Live Q&As have also helped voice concerns over the limited academic opportunities for postdocs in the life sciences. In his iBioMagazine talk and December Live Q&A Gregory Petsko suggested an economic model that involved doubling postdoc salaries to decrease the number of positions available and encourage graduate students to turn to nonacademic careers before the postdoctoral stage. In his March talk and Live Q&A, Keith Yamamoto countered that instead of doubling postdoc salaries, institutions be responsible for exposing graduate students to the array of career options available for a science PhD by providing programs and internship opportunities in nonacademic careers. He argued that allowing students to explore careers during graduate school should ultimately decrease the number of postdoctoral scholars while providing students with worthwhile and important options. Kristala Jones Prather gave an iBioSeminar on Synthetic Biology Arthur Horwich talked about chaperone-assisted protein folding The main entrance of the Central Campus, University of Khartoum 20 ASCB NEWSLETTER MARCH 2014 MARCH 2014 ASCB NEWSLETTER 21 Published by CBE Life Sciences Volume 13, Spring 2014 ascb the american society for cell biology Editorial Partner CBE Life Sciences Education www.lifescied.org Education Education Volume 13CBE—Life MarchSciences 2014 www.lifescied.org Volume 13 March 2014 Table of Contents Undergraduate Research Experiences: Approaches and Assessments Letters to the Editor Bruce Alberts and Ron Vale had a discussion about Science Education on iBiology Hangouts Keith Yamamoto took questions about graduate training and mentorship The next two iBiology Hangouts will take place in April and May. On April 10, Lydia Villa-Komaroff, Chief Scientific Officer at Cytonome/ST and co-founder of the Society for Advancement of Chicanos and Native Americans in Science, will be answering questions about her experiences in academia, industry, and science outreach in her Live Q&A “Composing a Life in Science.” Then, on May 7, iBiology will be hosting Jon Lorsch, the Director of the National Institute of General Medical Sciences. All of the iBiology Live Q&As are available on the iBiology.org website at www.ibiology.org/hangout-witha-scientist.html. Vision and Change through the Genome Consortium for Active Teaching Using Next-Generation Sequencing (GCAT-SEEK) Vincent Buonaccorsi, Mark Peterson, Gina Lamendella, Jeff Newman, Nancy Trun, Tammy Tobin, Andres Aguilar, Arthur Hunt, Craig Praul, Deborah Grove, Jim Roney, and Wade Roberts . . . . . . . . . . . . . . . . . . . . . . 1–2 Re: Misconceptions Are “So Yesterday!” Gregory J. Crowther and Rebecca M. Price . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3–5 FEATURES Approaches to Biology Teaching and Learning Considering the Role of Affect in Learning: Monitoring Students’ Self-Efficacy, Sense of Belonging, and Science Identity Gloriana Trujillo and Kimberly D. Tanner . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6–15 From the National Science Foundation Vision and Change in the Biology Community: Snapshots of Change Helen L. Vasaly, Jason Feser, Matthew D. Lettrich, Kevin Correa, and Katherine J. Denniston . . . . . . . . . . . . . . . . . . 16–20 New iBioSeminars Three new iBioSeminars are available in Cell Biology and Synthetic Biology. Arthur Horwich, who in a recent iBioMagazine talk shared his story of discovering chaperone-assisted protein folding, gave an in-depth iBioSeminars research talk about chaperones, their mechanisms of action, and their role in disease. In his talk, Robert Goldman gave an overview of intermediate filament properties and focused on nuclear lamins, which are a family of intermediate filaments found in the nucleus. Kristala Jones Prather introduced synthetic biology, which involves the application of engineering principles to biological systems to build “biological machines” and explained how her lab used design principles to engineer Escherichia coli to produce glucaric acid, which is not typically found in the organism, from glucose. WWW.Life Sciences Education Engaging with Molecular Form to Understand Function Nicola C. Barber and Louisa A. Stark . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21–24 Current Insights Recent Research in Science Teaching and Learning Deborah Allen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25–28 Meeting Report New Tools for Educators Recently, Nobel Laureate Elizabeth Blackburn’s talk on the discovery of telomerase and Arthur Horwich’s talk on the discovery of chaperones were added to the iBioEducation Discovery talk collection, in which first-hand accounts of famous discoveries taken from the iBioMagazine series are connected with the corresponding research papers. These talks, which can be accessed in the iBioEducation—Making Discoveries section of the website, also include a series of questions and suggested answers for educators. These questions were designed to encourage students to use critical and analytical thinking skills by reading and reflecting on primary literature. In addition, educators who register can access “Teaching Tools,” educational materials that accompany iBioSeminars and that include lecture notes, review questions, discussion questions, and suggestions for journal club papers. The latest Teaching Tools relate to Cori Bargmann’s iBioSeminar on the brain and behavior. To access any of the educational materials, register (for free) as an educator on iBiology.org. To receive updates on new releases in the future, sign up at www.ibiology.org/join.html. n — The iBiology Team Assessment of Course-Based Undergraduate Research Experiences: A Meeting Report Lisa Corwin Auchincloss, Sandra L. Laursen, Janet L. Branchaw, Kevin Eagan, Mark Graham, David I. Hanauer, Gwendolyn Lawrie, Colleen M. McLinn, Nancy Pelaez, Susan Rowland, Marcy Towns, Nancy M. Trautmann, Pratibha Varma-Nelson, Timothy J. Weston, and Erin L. Dolan . . . . . . . . . . . . 29–40 RESEARCH METHODS Is It the Intervention or the Students? Using Linear Regression to Control for Student Characteristics in Undergraduate STEM Education Research Roddy Theobald and Scott Freeman . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41–48 ESSAY Putting PhDs to Work: Career Planning for Today’s Scientist Jennifer A. Hobin, Philip S. Clifford, Ben M. Dunn, Susan Rich, and Louis B. Justement . . . . . . . . . . . . . . . . . . . . . . 49–53 ARTICLES Integrating Quantitative Thinking into an Introductory Biology Course Improves Students’ Mathematical Reasoning in Biological Contexts Susan Hester, Sanlyn Buxner, Lisa Elfring, and Lisa Nagy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 54–64 22 ASCB NEWSLETTER MARCH 2014 MARCH 2014 ASCB NEWSLETTER 23 Seen on THE CELL Be Part of The Cell Community An immunofluorescence image of human IMR90 lung fibroblasts stained for vinculin (green) and filamentous actin (magenta). Nuclei are stained blue. This image of untreated fibroblasts comes from a study of the changes in adhesion that accompany treatment to induce stem cells and can be used in hiPSC purification. The image was selected by the National Institute of General Medical Sciences (NIGMS) for inclusion in the May 2013 issue of Biomedical Beat, which features noteworthy NIGMS-supported research. See also Nat Meth 10:438-444. Image by Andres J. Garcia and Ankur Singh. This image is in the public domain and thus free of any copyright restrictions. However, as a matter of courtesy any user is encouraged to credit the content provider when reproducing the image. The Cell: An Image Library (www.cellimagelibrary.org) is a freely accessible, easy-tosearch, public repository of reviewed and annotated images, videos, and animations of cells from a variety of organisms, showcasing cell architecture, intracellular functionalities, and both normal and abnormal processes. Its purpose is to advance research, education, and training, with the ultimate goal of improving human health. The Cell continues to evolve. Since the site launched just over three years ago, it has had over 448,000 visits by over 339,000 visitors and has delivered over 1.7 million pageviews. It has more than 164,000 Facebook fans and has been accessed from 204 countries. The Cell has been a source of images for use in books, articles, and videos, on websites, and even on buildings. But it is much more. The Cell is: n A repository for material described in research articles n A source of images for use in education n A source of images for scientific research n A source of data for research in image processing The Cell was developed by ASCB under a Grand Opportunities grant from the National Institute of General Medical Sciences. Now The Cell has moved to the National Center for Microscopy and Imaging Research Cell Centered Database (CCDB), which manages the Library’s day-to-day operations under a perpetual license from ASCB. ASCB maintains a role in advertising the Library, soliciting images, serving as an advocate for the resource, and creating a community committed to The Cell-CCDB. n —David Orloff 24 ASCB NEWSLETTER MARCH 2014 MARCH 2014 ASCB NEWSLETTER • Pin your favorite cell images on Pinterest: http://pinterest.com/ davidnorloff/the-cell-an-imagelibrary-ccdb. • Sign up for a free account at The Cell so you can save images in folders for future reference: www. cellimagelibrary.org/accounts/login_ prompt. • Use the buttons on the detailed image pages to share images on Facebook, LinkedIn, StumbleUpon, and other social networks. • Join The Cell on Facebook (www. facebook.com/cellImageLibrary) or LinkedIn (www.linkedin.com/ groups?about=&gid=3733425). • Consider donating a tweet a day to The Cell at http://justcoz.org/ cellimagelibrar. • If you have used The Cell in interesting ways or in an article or are interested in submitting images or collaborating with The CellCCDB, please contact David Orloff at dorloff@ncmir.ucsd.edu. • Donate to The Cell to help it continue to grow. You can use the Donate button on the homepage. 25 The ASCB 2014 Call for Nominations HIGHLIGHTS from MBoC Bruce Alberts Award for Excellence in Science Education The Editorial Board of Molecular Biology of the Cell has highlighted the following articles from the February 2014 issues. From among the many fine articles in the journal, the Board selects for these Highlights articles that are of broad interest and significantly advance knowledge or provide new concepts or approaches that extend our understanding. Public Service Award Who is Eligible: An individual who has demonstrated innovative and sustained contributions to science education, with particular emphasis on the broad local, regional, and/or national impact of the nominee’s activities. Nominators must be ASCB members, but the candidate and support letter authors need not be. Who is Eligible: An individual who has demonstrated outstanding national leadership in support of biomedical research. Nominators must be ASCB members. The award winner may, but need not, be a scientist. How to Apply: Provide a letter of nomination, a maximum of three letters of support, and a CV. How to Apply: Provide a letter of nomination with a description of the nominee’s advocacy for, and promotion of, scientific research. Awards: The winner is presented a plaque and will give remarks at the Annual Meeting. Expenses to attend the Annual Meeting are paid. Awards: The winner gives the Public Service Award Lecture at the ASCB Annual Meeting and receives a certificate. Expenses to attend the Annual Meeting are paid. Deadline: April 1 (electronic submission to Thea Clarke at tclarke@ascb.org) Deadline: April 1 (electronic submission to Kevin Wilson at kwilson@ascb.org) Early Career Life Scientist Award Who is Eligible: An outstanding scientist who has served as an independent investigator for no more than seven years as of April 1. How to Apply: Provide a nominating package that includes a CV, brief research statement, nominating letter, and no more than three letters of support (at least one of which must come from outside the nominee’s institution). Nominators must be ASCB members. Awards: The winner is presented a plaque and a monetary prize and will speak in a Minisymposium at the Annual Meeting. Expenses to attend the Annual Meeting are paid. Deadline: April 1 (electronic submission to Christina Szalinski at cszalinski@ascb.org) E.B. Wilson Medal Who is Eligible: An individual who has demonstrated significant and far-reaching contributions to cell biology over a lifetime in science. Nominators must be ASCB members, but the candidate need not be. How to Apply: Provide a letter of nomination, the candidate’s CV, and no fewer than three, and no more than five, letters of support. Awards: The winner of the ASCB’s highest honor for science gives the E.B. Wilson Lecture at the Annual Meeting and receives the E.B. Wilson Medal. Expenses to attend the Annual Meeting are paid. Deadline: April 1 (electronic submission to ascbinfo@ascb.org) E.E. Just Lectureship Who is Eligible: A minority scientist who has demonstrated outstanding scientific achievement. Nominators must be ASCB members, but the candidate need not be. A stage-9 follicle (top) from a pxtEY/EY mutant Drosophila melanogaster and higher magnification images of the regions around the ring canals leading into the oocyte from each of the four posterior nurse cells (bottom). F-actin was labeled with phalloidin (white), and nuclei were labeled with DAPI (cyan). The images show the aberrant early actin remodeling, including extensive actin filaments and actin aggregates, emanating from the ring canals in the posterior nurse cells due to the loss of Pxt. See Mol. Biol. Cell 25, 397–411. (Image: Andrew J. Spracklen, Xiang Chen, and Tina Tootle, Department of Anatomy and Cell Biology, University of Iowa Carver College of Medicine) Soft matrix is a natural stimulator for cellular invasiveness Zhizhan Gu, Fei Liu, E. A. Tonkova, Soo Young Lee, D. J. Tschumperlin, and M. B. Brenner ECM softness (low stiffness comparable to soft tissues) alone is sufficient to prevent cell-to-cell adherens junction formation, up-regulate MMP secretion, promote MMP activity, and induce invadosome-like protrusion formation. Such findings suggest that cell invasion in vivo is a spontaneous cell behavior in response to ECM stiffness. Mol. Biol. Cell 25 (4), 457–469 Mutations that disrupt Ca2+-binding activity endow Doc2β with novel functional properties during synaptic transmission J. D. Gaffaney, Renhao Xue, and E. R. Chapman The C2A and C2B domains of Doc2 have markedly distinct Ca2+-sensing and lipid-binding properties. When expressed in wild-type neurons, a Ca2+-ligand mutant form of Doc2 that lacks apparent Ca2+-binding activity and is constitutively bound to the plasma membrane results in an anomalous enhancement of evoked and spontaneous synaptic transmission. Mol. Biol. Cell 25 (4), 481–494 n How to Apply: Provide a nomination package that includes a CV and a letter describing the nominee’s scientific achievement and mentoring support of underrepresented minority students and scientists. Awards: The winner gives the E.E. Just Lecture at the Annual Meeting and receives a plaque and a medal. Expenses to attend the Annual Meeting are paid. Deadline: April 1 (electronic submission to Deborah McCall at dmccall@ascb.org) WICB Awards Junior Award for Excellence in Research Who is Eligible: A woman in an early stage of her career (within six years of appointment to an independent position at the nomination deadline) who is making exceptional scientific contributions to cell biology, is developing a strong independent research program, and exhibits the potential for continuing at a high level of scientific endeavor and leadership. How to Apply: Provide a letter of nomination, a CV, and up to three letters of support, including at least one from outside the nominee’s institution. Mid-Career Award for Excellence in Research Who is Eligible: A woman at the mid-career level (7-15 years in an independent position at the nomination deadline) who has demonstrated a track record of exceptional scientific contributions to cell biology and/or has effectively translated cell biology across disciplines, and who exemplifies a high level of scientific endeavor and leadership. How to Apply: Provide a letter of nomination, a CV, and up to three letters of support, including at least one from outside the nominee’s institution. Senior Leadership Award Who is Eligible: A woman or man at a later career stage (generally full professor or equivalent) whose outstanding scientific achievements are coupled with a record of active leadership in mentoring both men and women in scientific careers. How to Apply: Provide a letter of nomination highlighting scientific achievements as well as examples of leadership and mentoring, a CV, and up to five letters of support. At least one letter must come from outside the nominee’s institution, and two must be from current or former mentees of the nominee. Letters should include specifics of the nominee’s mentoring history. Awards: Each winner is presented with an honorarium and a plaque at the ASCB Annual Meeting. Expenses to attend the Annual Meeting are paid. The Junior Awardee gives a talk in a minisymposium. Please note that candidates may be nominated more than once, and members of the WICB Committee are not eligible. Nominators must be ASCB members. Deadline: April 1 (electronic submission to wicb@ascb.org) Merton Bernfield Memorial Award Who is Eligible: An outstanding graduate student or postdoctoral fellow (at the time of nomination) who has excelled in research. How to Apply: The student or postdoc or his or her advisor should submit a one-page research statement, a CV, a list of publications, a copy of the abstract submitted to the current year’s Annual Meeting, and the advisor’s letter of recommendation. Postdocs may also submit the recommendation of their graduate student advisor. Duplicate applications from graduate students may be submitted for the Gilula and Bernfield Memorial Awards. Nominators or self-nominators must be ASCB members. Awards: The winner is presented a plaque, is given financial support, and will speak at a Minisymposium at the Annual Meeting. Expenses to attend the Annual Meeting are paid. Deadline: July 15 (electronic submission to ascbinfo@ascb.org) Norton B. Gilula Memorial Award Who is Eligible: An outstanding graduate or undergraduate student (at the time of nomination) who has excelled in research or first-year postdocs whose work was performed while a PhD or MD/PhD student. How to Apply: The student or advisor should submit a one-page research statement, a CV, a list of publications, if any, the abstract submitted to the current year’s Annual Meeting, and the advisor’s letter of recommendation. Duplicate applications from graduate students may be submitted for the Gilula and Bernfield Memorial Awards. Nominators or self-nominators must be ASCB members. Awards: The winner is presented a plaque and a ribbon for his/her poster board. Expenses to attend the Annual Meeting are paid. Funded by an annual grant from Rockefeller University Press. Deadline: July 15 (electronic submission to ascbinfo@ascb.org) For names of prior awardees or more information, visit www.ascb.org and click on “Membership” or contact the ASCB at 301-347-9300 or ascbinfo@ascb.org. 26 ASCB NEWSLETTER MARCH 2014 MARCH 2014 ASCB NEWSLETTER 27 GRANTS & OPPORTUNITIES A list of current grant and other opportunities can be found at www.ascb.org/grants. The following items were added since the last issue of the Newsletter: American Society for Biochemistry and Molecular Biology (ASBMB) Grant Writing Workshop. ASBMB seeks nominations for assistant professors and senior postdoctoral researchers to participate in its 2014 Grant Writing Workshop, June 12–14, 2014, in Washington, DC. Application deadline: May 2, 2014. www.asbmb.org/grantwriting. Faculty Early Career Development (CAREER) Program. The CAREER Program is a Foundation-wide activity that offers the National Science Foundation’s (NSF’s) most prestigious awards in support of junior faculty who exemplify the role of teacher-scholars through outstanding research, excellent education, and the integration of education and research within the context of the mission of their organizations. In addition, each year NSF selects nominees for the Presidential Early Career Awards for Scientists and Engineers (PECASE) from among the most meritorious recent CAREER awardees. The White House Office of Science and Technology Policy makes the final selection and announcement of the awardees. Application deadline: July 21, 2014. www.nsf.gov/funding/ pgm_summ.jsp?pims_id=503214. Grant Opportunities for Academic Liaison with Industry (GOALI). The National Science Foundation GOALI program promotes university–industry partnerships by making project funds or fellowships/traineeships available to support an eclectic mix of industry–university linkages. The program targets highrisk/high-gain research with a focus on fundamental research, new approaches to solving generic problems, development of innovative collaborative industry– university educational programs, and direct transfer of new knowledge between academe and industry. GOALI seeks to fund transformative research that lies beyond that which industry would normally fund. Contact program office for deadlines. http://www.nsf.gov/funding/pgm_summ.jsp?pims_id=504699. Howard Hughes Medical Institute (HHMI) Competition to Appoint New HHMI Investigators. HHMI seeks to appoint 20–25 outstanding scientists who are basic researchers and physician scientists studying significant biological problems in all biomedical disciplines, including plant biology, as well as in adjacent fields such as evolutionary biology, biophysics, chemical biology, biomedical engineering, and computational biology. Application deadline: June 3, 2014. www.hhmi.org/programs/biomedical-research/investigator-program. Research Experiences for Undergraduates (REU). The National Science Foundation (NSF) REU program supports active research participation by undergraduate students in any of the areas of research funded by the NSF. REU projects involve students in meaningful ways in ongoing research programs or in research projects specifically designed for the REU program. There are two mechanisms for support of student research: (1) REU Sites are based on independent proposals to initiate and conduct projects that engage a number of students in research. REU Sites may be based in a single discipline or academic department or may offer interdisciplinary or multi-department research opportunities with a coherent intellectual theme. Proposals with an international dimension are welcome. (2) REU Supplements may be included as a component of proposals for new or renewal NSF grants or cooperative agreements or may be requested for ongoing NSF-funded research projects. Application Deadline: August 27, 2014. www.nsf.gov/funding/pgm_summ. jsp?pims_id=5517. “ASCB,” “The American Society for Cell Biology,” “iBioSeminars,” and “Molecular Biology of the Cell” are registered trademarks of The American Society for Cell Biology. “The Cell: An Image Library” is a common law trademark of The American Society for Cell Biology. A complete list of upcoming meetings can be found at http:// ascb.org/global-meetings-calendar. The following meeting was added since the last issue of the Newsletter: August 5–9, 2014. Winnipeg, Canada First International Summer Institute of Scientific Teaching and Educational Leadership for Bioscience Researchers. http://umanitoba.ca/medicine/ institutes/ineds. ASCB Annual Meetings December 6–10, 2014. Philadelphia December 12–16, 2015. San Diego December 3–7, 2016. San Francisco December 2–6, 2017. Philadelphia December 8–12, 2018. San Diego The world of slime molds is seething with activity as teams prepare their entries for the upcoming Dicty World Race, set for May 16 in the Massachusetts General Hospital lab of Daniel Irimia. Meantime, Irimia and ASCB member Chris Janetopoulos of Vanderbilt University have raised $3,000 from private sponsors for prize money. Their goal now is to raise the grand prize to $5,000 through crowd funding on RocketHub (www.rockethub.com/projects/39942-dicty-world-race2014#description-tab). The idea that you could win real money racing Dictyostelium discoideum is startling. Imagine cell biology on the sports pages. Give generously. n Smooth, sensitive meniscus control... accu-jet pro ® Advanced speed control ends meniscus “jumping,” and soft blow-out has never been easier! • Protectyourcells: Selectable maximum speed for ultra-sensitive operations • Precisecontrol: Touchsensitive,continuously variable speed control • Ergonomic: Scultped grip eliminates uncomfortable pressure points ASCB Member Comments We welcome your comments and suggestions at ascbinfo@ascb.org n Members in the News Clifford Brangwynne, of Princeton University, an ASCB member since 2013, was awarded a $50,000 early-career scientist research fellowship by the Alfred P. Sloan Foundation. Sally Kornbluth, who first became an ASCB member in 2000, has been named provost of Duke University. She will assume the position on July 1. Dicty Racers Vie for Big Cash Prize 28 MEETINGS Calendar Elaine Fuchs, of The Rockefeller University, an ASCB member since 1980 and 2001 ASCB President, will receive the 2014 Pezcoller Foundation–AACR International Award for Cancer Research from the American Association for Cancer Research. Lab Rats Trust BrandTech®! ® Toll Free 888-522-2726 Product & promotion details at www.brandtech.com ASCB Member Benefit: Publicize Your Book Are you publishing a book? If so, let ASCB know! Send the title, publisher, ISBN information, and a thumbnail (300 dpi) of the cover. We’ll include it in the ASCB Newsletter. This publicity is available only to ASCB members. Please send submissions to Thea Clarke at tclarke@ascb.org. n Volunteer to Review CVs We are always looking for more volunteers, especially ASCB members in industry, to help review cover letters, CVs, and resumes online for young ASCB scientists. If you can help, please contact Thea Clarke at tclarke@ascb.org. n ASCB NEWSLETTER MARCH 2014 MARCH 2014 ASCB NEWSLETTER 29 New ASCB Members 1,406 new members were approved by the ASCB Council from June–December 2013. Nikka Abaricia Genevieve Abbruzzese Ammara Abdullah Robert Aboukhalil Maria Acevedo Yvess Adamian Arlo Adams Shaquria Adderley Gbenga Adefolaju Neema Adhami Evgenia Afanasieva Megan Agajanian Hiroshi Ageta Smriti Agrawal Ivie Aifuwa Jayne Aiken Michael Ailion Tara Kafiyeh Akhshi Ryutaro Akiyoshi Hikmat Al Hashimi Lauren Albrecht Antigoni Alexandrou Isma Ali Anna Allen Amanda Allred Maria Almonacid Annabel Alonso Varisce Alston Faisal Alturkistany Rojelio Alvarado Arun Anantharam Sirinart Ananvoranich Kate Anderson David Ando Darrell Andrews Wei Tzer Ang Dimitrios Angelis Stephane Angers Damodaran Annamalai Neil Anthony Kunio Arai Alexander Aranovich Edwin Arauz Diaz Jessica Arden Elisabetta Argenzio Torey Arnold Reety Arora David Artus Avathamsa Athirasala Samantha Atkinson John Attia Jessica Aughenbaugh Anita Autry Armine Avetisyan Cassandra Awgulewitsch Swathi Ayloo Fernanda Azevedo Ingolf Bach Anthony Baglio Ruchi Bajpai Vedrana Bali Martial Balland Danielle Ballard Eleonora Balloi Je Young Bang Amorette Barber Matthew Barber Amy Barker Elizabeth Barker Liron Bar-Peled Peter Barrett Raymond Barry Gizem Bati Vishnu Priya Battini Mathias Bayer Hayley Beaton David Beauchemin Katherine Beaufait Moriah Beck Tim Beck Chris Beecher 30 Clémence Belleannée Amir Ben-Shmuel Ron Benyair Gregory Berbusse Cristina Berciu Judith Bergboer Slobodan Beronja Aurelie Bertin Tracey Beyer Bidur Bhandary Ramray Bhat Nilakshee Bhattacharya Janardhan Bhattarai Alex Bicket Tamara Bidone Noah Bierwirth Praveen Kumar Bingi Marco Biondini Arunima Biswas Natalya Blessing Stephanie Blij Rostyslav Blume Dani Bodor Michiel Boekhout Alexander Bogdan Lawrence Boise Ashley Bonneau Richard Bonneau Betty Booker Elizabeth Booth Alicia Bornert Marion Bouchecareilh Laure Bouchez Jeff Bouffard Imene Bouhlel Camille Bourgeois Shanna Bowersox Nicholas Boyer Mary Bradford Kenneth Bradley Arujun Brahmendra Daniel Brambilla Kevin Brasseur Andrea Brear Jeffrey Breidigan Catherine Brennan Andrew Bridges Lydia Bright Eric Britigan Francisca Bronfman Rebecca Brooks Kristen Browder Josephine Brown Zhane Brown Jamie Bruce Agusti Brugues Wytse Bruinsma Rebecca Buckley Kendrick Buford Beata Bugyi Patricia Burgos Thomas Burke Austin Burkenstock Bharat Burman Kyle Burns Leslie Burtnick David Busch Marc Busch Silke Busch Adina Buxbaum Angel Byrd Elliot Byrne Paulo Caceres Nicole Caesar Cori Cahoon Danfeng Cai Olson Calla Cristel Camacho Antonio Camacho Flores Alessandra Cambi Daniel Caminada Rhiannon Campden Aude Cannet Andrea Cantu Laura Canty Dan Cao Ruofan Cao Jennifer Carroll Robert Carroll Andy Carson Jack Carter Bethany Cartwright Ian Casci Silvia Castellanos Castro Ines Castro Petra Cela Oscar Cerda Estela Cerri Paulo Cerri Marcella Cervantes Richard Chadwick Shigeru Chaen Agathe Chaigne Yupaporn Chaiseha Leo Chan Chelsey Chandler Dhyan Chandra Amy Chang Bliss Chang Lin Chun Chang YoonJeung Chang Rima Chattopadhyay Pavithra Chavali Frances Chaves Ching-Cheng Chen Guangbo Chen Haodong Chen Qichuan Chen Yi-Shan Chen Yongfen Chen Devon Chenette Zishuo Cheng Alice Chen-Liaw Venugoapaln Cheriyath Kevin Cheung Leon Chew Nicolas Chiaruttini Ming-Shan Chien Jerry Chipuk Zeinab Chitforoush Patrick Chitwood Hyejin Cho IChun Cho Chong Pyo Choe Bongkun Choi JongRyoul Choi Suyong Choi Wangsun Choi Jenna Christensen Miensheng Chu Priyamvada Chugh Ki Wha Chung Dolores Ciufo Mary Clancy Manuella Clark-Cotton Scott Clarke Cedric Cleyrat Katie Cockburn Idan Cohen Gheorghe Cojoc David Coleman John Colicelli Carol Collins Meredith Collins Sarah Compton Angela Conforti Michael Conrad Veronica Contreras-Shannon Peter Cook Matthieu Coppey Eli Cornblath Luisa Coronel Charlie Corredor David Courson Thibault Courtellemont Kester Coutinho Adriana Covarrubias Scott Coyle Susanne Cranz-Mileva Anna Crater Rebecca Crawford Katherine Creath Alvaro Crevenna Amy Crooks Sean Crosson David Crottes Gage Crump Glenn Cruse Sandra Cuffe Brian Cunniff Kara Curley Natalia Cursino Eshan Dahal Joseph Daigle Owen Daly Irene Dang Joseph Daniele Jose Daniotti Louise Darling Anupam Das Sanchaita Das Victoria Dauphin Amanda Davis John Robert Davis Kasey Day Monica Dayam Alejandro D’Brot Giovanna De Brito Matthew Dean Shirley Dean Sarah Deffit Joshua Dehart Samineh Deheshi Lauren Del Bel Marie Delattre Manuel Delgado-Velez Ryan Dellinger Rachel DeLong Michael DeNiro Connor Denison Cassandra Dennys Patrick Derksen Nathan Derr Paurav Desai Raj Desai Morgan DeSantis Christine Dethlefsen Dominic Devost Mark DeWitt Swagata Dey So Hee Dho Bruno Di Stefano Amalie Dick Lindsey Dickson Stefan Diez Chadwick Dillon Xiaoyan Ding Yi-Shan Ding Shandee Dixon Danh Do Megan Dobro Niv Dobzinski Travis Doggett Motomichi Doi Dasa Dolezalova Renee Dominguez Dominique Donato Rui Dong Shengli Dong Sara Donnelly David Doobin Gail Doughton Julia Draper Yue Du Sabrina Dumas Guillaume Dumenil Camille Duran Sevi Durdu David Dursunian Samantha Dykes Vinay Eapen Stephen Eaton Vivienne Echendu Martha Echevarria Andino Gretchen Edwalds-Gilbert Nadia Efimova Thibaut Eguether Nathaniel Eiseman Eman Elbassuoni Andrew Elliott Jessica Ellis Stephanie Ellis Mohamed El-Mogy Alberto Elosegui-Artola German Enciso Hiroko Endo Roman Erdmann Sylvia Evans William Evenson Helge Ewers Francois Fabi Grant Fairchild Veronica Farmer Nicole Fay Shea Feeney Jeffrey Fein Megan Fekete Isabella Felzer-Kim Marina Feric Vilaiwan Fernandes Luis Jose Fernandez Jose Ferreira Maidy Ferreira Gabriela Ferreira-Fuentes Nicolas Ferry William Figg Claudia Figueroa-Romero Dany Fillion Laura Finerty Taylor Firman Ivy Fitzgerald Anne-Marie Flanagan Arnau Flaquer Emily Foley Joseph Fong Loren Fong Wendy Fong Alice Ford Diana Ford Scott Forth Olivia Foster Peter Foster Susanna Fox Fiona Francis Nagat Frara James Freyer Jeffrey Frost Tristan Frum Afu Fu Jiang Fu William Furlow Shamira Furman Kayla Fuselier Lalitha Gaddipati Vladimir Gainullin Paul Galardy Clemence Gamblin Archan Ganguly Guang Gao Claudia Garay Canales Manuel Garcia Valentina Garcia Refugio Garcia-Villegas Pierre Garcin ASCB NEWSLETTER MARCH 2014 Jennifer Garrison Ivana Gasic Hoda Gebril Fernand-Pierre Gendron Abigail Gerhold Flávia Ghiraldini Vikram Ghugtyal Melissa Gilbert-Ross Stephanie Gillespie Christopher Gilmartin Paul Ginno Monica Gireud Elisa Giusto Megan Gnazzo Allysa Marie Go Daryl Goad Joshua Godwin Victor Goitea Jodi Goldberg Mindy Goldsborough Thiago Gomes Adam Gomez Diego Gomez Emily Gong Erica Gorenberg Harry Gould Erika Grajales-Esquivel Natalia Grane-Boladeras Matthias Granold Matthew Graus Alana Gray Kevin Gray Sarah Greene William Greenleaf Andrew Grenfell Kathy Grenier Jérôme Grenier-Naud Edward Griffin Amber Griffith Ken Griffith Ashley Grimaldi Jennifer Groebner Depresia Grogan Thomas Gronemeyer Peter Gross Christophe Guérin Giovanna Guerrero-Medina Amber Guidry Christophe Guilluy Dilani Gunasena Yanlin Guo Arnab Gupta Ritu Gurung Richard Guyer Michael Guzman Nastaran Hadizadeh Yazdi Mohammad Haider Eric Haines Nadia Halidi Conrad Hall Jessica Hall Rabia Hameed Laura Hamel Alan Hammer Bing Han Sangyoon Han Shengcheng Han Tina Han Julia Hand Samer Hanna Tawny Hanna Brittany Hannible Ying Hao Nicoletta Harabor Emily Harasym Masahiko Harata Hanaa Hariri Michael Harman Robert Harmon Hayaa Hashemi Matthew Hatkoff Scott Hayes Liz Haynes Dan Hayward Jing He Lydia Heasley Carissa Heath Anna Hegsted Margaret Heider Amy Heidersbach David Heisler Emmanuele Helfer Beric Henderson Charles Hendricks Sun-Hee Heo Sahan Herath Kathleen Hering-Smith Paul Herman Sebastien Herzig Brennan Hicks Yeri Hien Ayana Hinton Junko Hirata Anna-Stina Höglund Andrew Hollenbach Nancy Hom Damek Homiack Miyoun Hong Shiao-Ya Hong Jing Ling Hoon Mary Horgan John Houser Jessica Houston Danielle Howell Wen-Chieh Hsieh HanHsiu Hsu Joseph KuangWu Hsu Meng-Chieh Hsu Ya-Chu Juliana Hsu Rong Hua Hao Huang Junqi Huang Mu Ching Huang Nai-Jia Huang Robert Huebner Adam Hughes Kevin Hughes Zhang Hui Chao-wei Hung Emily Hunter Ginger Hunter Morgan Huse Julie Huynh Kwangwoo Hwang Soojin Hwang Young Se Hyun Jose Anselmo Ibarra Kazuho Ikeda Maria Ioannou Jerome Irianto Adam Isabella Kendra Ivy Satoru Iwata Matthew Iyer Patricia Izbicki Ignacio Izeddin Jelena Jablanovic Torey Jacques Jennifer Jakubowski Michael James Kerstin Maria Janisch Harald Janovjak Matti Javanainen Vaishali Jayashankar Heather Jensen Smith Won Bae Jeon Hao Jiang Tao Jiang Viridiana Jimenez Chengcheng Jin Adiv Johnson Alex Johnson Christopher Johnson Debra Johnson Dwiesha Johnson Laura Johnson Adam Johnston Grace Johnston Shaili Johri Vahbiz Jokhi Mathew Jones Elavarasi Joseph David Jukam Miri Jwa Zahra Kabiri Rohinton Kamakaka Konstantin Kandror Yosef Kaplan Dor Aastha Kapoor Eva Karasmanis MARCH 2014 ASCB NEWSLETTER Fumihiko Katagiri Pekka Katajisto Naohiro Kato Toshiaki Kato Daiki Katoh Brett Kaufman Yasushi Kawagoe Bryan Kaye Julhash Kazi Lindsay Kelly Rhiannon Kelsh James Kemp Anissa Kempf Tyler Kennedy Jonathan Kessler Maryam Khalaj Ashjan Khalel Shahriar Khan Chayeon Kim Gwang-Su Kim Hyejin Kim Jeyun Kim Joo Yeon Kim Se-Na Kim Taekyung Kim Yoo Jung Kim Gwendalyn King Jacob Kirkland Grace Kisirkoi Erin Kitten Adam Kleinschmit Olga Klipa Erik Knelson Hotaka Kobayashi Leyla Kocgozlu Marcela Kokes Narayana Komaravelli Dong Kong Ji Na Kong Bon Cheol Koo Viola Kooij Benjamin Kopek Korey Koper Rajshekhar Kore Ludek Koreny Nora Kory Kosmas Kosmas Mounir Koussa Anthony Kovacs Agne Kozlovskaja-Gumbriene Marilyne Kpetemey Elliot Kramer Katherine Kretovich Heike Kroeger Thomas Kruse Tomohiro Kubo Sho Kubota Markus Kuehn Dmitry Kuksin Priyadarsini Kumar Masataka Kunii Emily Kurdzo Sharon Kuss Aurelia Kuster Sergey Kuznetsov Daekee Kwon John Kwon Anatalia Labilloy Melissa LaBonty Marine Lacomme Suzette Laing Dollie LaJoie Mark Lalli Wanwen Lan Charlene Lancaster Christian Lanctot Terry Landowski Aaron Landry Emily Lane Michael Lanier Laetitia Laurent Elvin Lauron Lena Lautscham Kari Lavik Kelsey Law Anthony Lawrenz Aurélie Le Page Sandra Leal Jonathan Leano Aaron Ledray Amanda Lee Byeong Lee Geumhwa Lee Howard Lee Hwa-Young Lee Jae Wook Lee Ji Eun Lee Jui-Hao Lee Kristen Lee Mid Eum Lee Misu Lee Sanghee Lee Siu Lee Yi-Hsuan Lee Irene Lee Rivera Jaakko Lehtimaki Nikolaus Leisch Josephine Lembong Kari Lenhart Lanfranco Leo Maria Leptin Robert Lera Connie Lerma Cervantes Tera Levin Sarah Levinson Dong Li Lishi Li Pei-Tzu Li Wenting Li Wenyan Li Yu Li Kif Liakath-Ali Chun-Chi Liang Jialiang Liang Liang Liang Pin-Chao Liao Swee Lim Shih-Yi Lin Yu-Chun Lin Yu-Huey Lin Lasse Lindahl Jiangshu Liu Jing Liu Liqiong Liu Tina Liu Tony Liu Xiaji Liu Xiaoyong Liu John Livesey Maxwell Lloyd Wan-Sheng Lo Viola Lobert Kristopher Lofgren Lauren Lohmer Ursula Loizides Jo Lomax Marcus Long Whitney Longmate Martin Loose Nicole Lopez Alfonso Lopez Coral Sofiane Lotmani David Lounsbury Jacob Loupe Sarina Lowe Mengxiao Lu Quanlong Lu Andrei Luchici Minmin Luo Peter Ly Lani Lyman-Henley Andrew Lyon John Macbeth Patrick Macdonald João Machado-Neto John Maciejowski Daniel Madsen Elaine Maggi Andrew Magimaidas Anniefer Magpusao Ahmed Mahmoud Stephanie Maiden Alishba Maira Waqar Majeed Francesca Malvezzi Barbara Mann Emad Manni Lathiena Manning Kai Mao Suresh Marada Anu Marahatta Marina Marcola Mohan Prem Anand Marimuthu Matthew Marlin Melvenia Martin Roberta Martinelli Bryan Martinez Frank Mason Norbert Massie Mathieu Mateo Tsubasa Matsui Yoshimitsu Matsui Yohei Matsunaga Adam Matthews Irene Mattiola Jessica Matts Adriana Mauricio Anderson Mayfield Thibault Mayor Mazvita Maziveyi Christine McBride Mark McClintock Kelsey McCoy Nathan McDonald Caitlin McDonold Luke McDougall Alexander McFarland Claire McGraw Brendan McKeown Kara McKinley Tiffany McLamarrah Ashley McMicahel Patrick McNeely Varsha Meghnani Nicolas Melin Nora Mellouk Juan Mendoza Brielle Menegazzi Dan Meng Gretchen Meyer Yong Miao Maria Mikedis Daniel Milano Jess Millar Austin Miller Megan Miller Ana Milunovic-Jevtic Mingwei Min Gregory Miner Itsushi Minoura Jennifer Miskowski Satyajayant Misra Kasturi Mitra Raka Mitra Katsuya Miyake Katherine Mladinich Arie Mobley Souvik Modi Lishibanya Mohapatra Samuel Molina Cristiana Mollinari Carine Monat Marco Monroy Tomika Moody Desmond Moore Luis Henrique Moraes Nicholas Morales Drielen Moreira Norma Morella Xavier Morin Takanobu Moriuchi Alexandre Morozov Jonathan Morris Kathryn Morris Tammy Morrish Eric Morrow Mary Morton Hakhamanesh Mostafavi Stephanie Moya Kevin Mroz Olga Mudrak Irina Mueller Felix Muerdter Rafiq Muhammad Soumya Mukherjee Lisa Mullee Timothy Mullen Charlee Mulligan Daniel Mulvihill 31 Imran Mungrue Andrew Muroyama Lyndsay Murrow Sricharan Murugesan Rene Musters Layne Myhre Sua Myong Ambika Nadkarni Kaleb Naegeli Takeharu Nagai Makoto Nagano Wallis Nahaboo Shotaro Nakajima Elizabeth Nakasone Asuka Nakata Khriezhanuo Nakhro Soo Nam Jeremy Nance Ramiro Nandez Andrea Naranjo Patrick Narbonne Kanmani Natarajan Apurba Nath Robert Natividad Timo Nazari-Shafti Tambudzai Ndashe Michaela Nejedla Pascal 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Chengchao Xu Chuan Xu Peng Xu Hikaru Yamaguchi Naoya Yamaguchi Yuji Yamamoto Xiaohui Yan Chao Yang Dong Hee Yang Fan Yang Guang Yang Jin Yang Li Yang Li-Ling Yang Ming Yang Hsin-Fang Yang-Yen Zhizhong Yao Jordan Yaron Eric Yen Kendrick Yim Hanwei Yin Haneul Yoo Tae Yeon Yoo BoRam Yoon Hiroshi Yorifuji Amanda York Richard Youle Hui-Chia Yu Olivia Yu Yangjinqi Yu Xiaobing Yuan Arif Yurdagul Sofia Zanin Jingwen Zeng Yukai Zeng Serhan Zenger Elizabeth Zhang Haoyue Zhang Huadi Zhang Hui Zhang Jin Zhang Peng Cheng Zhang Qiao Zhang Xun Zhang Amy Zhao Dongjiao Zhao Lyandysha Zholudeva Ruyun Zhou Ya Zhou Tongge Zhu Wei Zhu Yili Zhu Ceniz Zihni Amanda Zirzow Hailing Zong Zhongyuan Zuo Six ASCB members were granted Emeritus status at the Fall Council Meeting Mark A L Atkinson Mary Bell Wendy F. Boss Margaret R. Kasschau William J. Smith Leslie Wilson ASCB Member Gifts The ASCB is grateful to the following donors whose contributions between February 1, 2013, and January 31, 2014, support Society activities: Gold ($1,000 and up) Bruce Alberts Carmela Pasternak Georjana Barnes Thoru Pederson Stefano Bertuzzi James Sabry Don Cleveland Sandra Schmid Anne Cress Huntington Sheldon David Drubin Mary Ann Stepp Joseph Gall Taneli Tani Sandra Masur Kenneth Yamada Tom Misteli Silver ($500 to $999) William Bement Kerry Bloom Henry Brown Jayme Dyer Robert Goldman and Anne Goldman Daniel Lew Timothy Mitchison and Christine Field Tim Schedl Jonathan Scholey Sustainer (up to $249) Hiroshi Abe Josephine Adams Robert Adelstein Yamac Akgun Franklin Ampy Suzanne Barbour Valarie Barr Lance Barton Alexander Bershadsky Gregory Bertoni Daphne Blumberg Elizabeth Brandon Michael Brown Keith Burridge Rosaleen Calvert Andrew Campbell Merri Casem J. 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James Nelson Margaret Magendantz Richard Mains J. McIntosh Philip McQueen Wilfredo Mellado Rita Miller David Mitchell Phillip Mitchem Jenifer Monks Marco Monroy Veronica Morandi Da Silva Tammy Morrish David Moscatello Anthony Moss Elena Nadezhdina Mohandas Narla Terry Newcomb Heber Nielsen Carien Niessen Zhaoyang Niu Berl Oakley Pyong Woo Park Linda Parysek Jenish Patel Sara Patterson Jessica Polka Sharon Presnell Richard Rachubinski Elizabeth Raff Evelyn Ralston Laura Rhoads Jonathan Rothblatt Edward Salmon Jaakko Saraste William Saxton Sol Sepsenwol W. Shafer Caroline Shamu Vivian Siegel Forrest Spencer Barbara Stebbins-Boaz Clifford Steer Janet Stein Donna Stolz Brian Storrie Daniel Strongin Cristian Suarez Elizabeth Sztul Kelly Tatchell Henry Tomasiewicz Katharine Ullman Barbara Vertel Claire Walczak Ruoxing Wang Wendy Westbroek Katherine Wilson Cortney Winkle Maureen Wirschell Joerg Wissler Tadashi Yamamoto C.Y. Irene Yan 33 DEAR Labby Paying It Forward Dear Labby, I have reason to be thankful to a number of senior faculty members at my former institution and elsewhere after I was denied tenure. There are some who supported me through my appeal process and search for a new position, by conversations and letters of support. Another champion worked hard to snatch me up for her institution. What is an appropriate, ethical way to thank these people: my advocates in other institutions, my local colleagues, and especially my new colleague who I hope will be a longterm neighbor? I will send emails of thanks once my career trajectory is resecured, but would a token of my appreciation be appropriate, say a fruit basket or book for distant contacts and a night out at a wine bar with my local group? For my champion with whom I may be working for the next two decades, may I give her something more than my loyalty in future departmental ventures, like tickets to a show she might like to see with a family member? What are the ethics of giving gifts to say thank you? I enjoy your column and respect your advice. Thank you for considering my question. —Sensitively Appreciative Dear Sensitively Appreciative, What you suggest is very thoughtful, but I wouldn’t underestimate how already “gifted” these fine colleagues and supporters feel by having helped you. Seeing an admired colleague succeed, especially if it is accompanied by a sense of right winning out, is a powerful dose of gratification. Although the tangible gifts you are pondering are all lovely ideas, they really don’t come close to the gift these fine people have already received by knowing that their efforts were successful. I would advise a simple, hand-written note to each, perhaps adding something like “The way I hope to truly say thank you and repay you for your wonderful support is to be the same stalwart champion of others as a colleague, mentor, and friend.” n —Labby CBE Life Sciences Education www.lifescied.org A Peer-Reviewed Journal of Biology Education Research and Evidence-Based Biology Teaching For educators at all levels and across all life science disciplines. Online and completely FREE. No subscription required. LSE emphasizes teaching innovations and evidence of their effectiveness. It publishes original research articles, essays, and features that help you apply education research to your own teaching. No author page or color charges. Published by Editorial Partner ascb the american society for cell biology Funded in part by the Howard Hughes Medical Institute 34 ASCB NEWSLETTER MARCH 2014 8120 Woodmont Avenue Suite 750 Bethesda, MD 20814-2762 USA Non-profit Organization US Postage PAID York, PA Permit No. 356 Working at the intersection of cell biology and the physical/computational sciences? Submit Your Work for the MBoC Special Issue on Quantitative Biology Jennifer Lippincott-Schwartz, Guest Editor Recognizing the profound influence that concepts and technologies from the physical and computational sciences are having on cell biology, Molecular Biology of the Cell (MBoC) welcomes research articles, including methods papers, in: n Quantitative Imaging n Superresolution imaging techniques and their applications n Biophysical properties of cells and cell structures n Computational and mathematical modeling n Systems studies of cell signaling and complex physiological processes n Innovative physical or computational approaches to cell biological problems Jennifer Lippincott-Schwartz Work in these areas is welcome at all times, but submission now may allow it to be included in the November 2014 special issue on Quantitative Biology. 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