Final Program

Transcription

Final Program

Volume 77
November 2007
Final Program
Number 5
American Society of Tropical Medicine and Hygiene
56th Annual Meeting
th
AnnualMeeting
ASTMH
November 4–8, 2007
ASTMH
Philadelphia Marriott Downtown
AnnualMeeting
th
Philadelphia, Pennsylvania USA
Supplement to
The American Journal of
Tropical Medicine and Hygiene
ASTMH Thanks the 56th Annual Meeting Supporters
Bill & Melinda Gates Foundation
The Burroughs Wellcome Fund
Companion Animal Parasite Council
GlaxoSmithKline
International Association for Medical
Assistance to Travelers
National Institutes of Health/
National Institute of Allergy and Infectious Diseases
Novartis Pharma AG.
sanofi aventis
Sigma-Tau Pharmaceuticals, Inc.
TechLab Inc.
www.astmh.org
ASTMH
th
See the ASTMH 56th Annual Meeting
Abstract Book, included with your
registration packet, to view the full text of
abstracts presented at the annual meeting.
November 4–8, 2007
Philadelphia, Pennsylvania USA
AnnualMeeting
Table of Contents
Annual Meeting Supporters . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .2
Schedule-at-a-Glance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .6
Program Changes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .6
Schedule Grid . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .8
Affiliate Meeting Schedule . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .17
ASTMH Council, Committee and Subgroup Meetings . . . . . . . . .19
Officers and Councilors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .20
Scientific Program Committee . . . . . . . . . . . . . . . . . . . . . . . . . . . .21
ASTMH Committees and Subgroups . . . . . . . . . . . . . . . . . . . . . . .22
ASTMH Headquarters . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .23
Affiliate Members . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .24
Travel Awards
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .24
Continuing Medical Education . . . . . . . . . . . . . . . . . . . . . . . . . . . .25
Registration Hours . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .25
www.astmh.org
About the American Society of Tropical
Medicine and Hygiene (ASTMH)
ASTMH is the principal organization in the United States
representing scientists, clinicians and others with interests
in the prevention and control of tropical diseases and diseases of global health import. The interests of the society are
in tropical medicine, including the varied parasitic and viral
diseases of the tropics, as well as other infectious diseases,
such as enteric and mycobacterial infections. ASTMH members include those with clinical, epidemiological, programmatic and basic biochemical, immunologic and molecular
approaches to both diseases and pathogens. Within the
society are various active subgroups with specific interests,
such as medical entomology, arbovirology, molecular parasitology and clinical tropical diseases. The mission of ASTMH
is to promote global health by the prevention and control of
tropical diseases through research and education.
Join the American Society of
Tropical Medicine and Hygiene
Session Audio Recording . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .27
We invite you to join ASTMH and benefit from membership
in the premier international organization for scientists
involved in tropical medicine and global health. ASTMH
provides a forum for sharing scientific advances, exchanging
ideas, fostering new research and providing professional
education. See the membership application on page 233.
Late Breaker Abstracts . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .27
Questions
Meet the Professors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .27
If you have any questions regarding the program or registration, visit the ASTMH registration desk in the Grand Ballroom
Foyer.
Messages and Emergency Calls . . . . . . . . . . . . . . . . . . . . . . . . . . .25
Exhibits . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .26
Employment Opportunities . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .26
Student Reception and Other Student/Trainee Activities . . . . .28
Poster Sessions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .30
Speaker Ready Room and Audio-Visual Guidelines . . . . . . . . . .30
Future Annual Meeting Dates
. . . . . . . . . . . . . . . . . . . . . . . . . . .31
Video Presentations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .32
Detailed Program . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .34
Abstract Author Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .213
Speaker and Session Chair Index . . . . . . . . . . . . . . . . . . . . . . . . . .234
Membership Application . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .237
Meeting Room Floor Plan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .238
Schedule-at-a-Glance
www.astmh.org
Program Changes
The time and/or location of any activity or session is subject to change. Notices of program changes will be posted in the ASTMH registration area.
A Program Update is included in your registration packet.
Friday, November 2
12:15 p.m. – 1:15 p.m.
Meet the Professors and Mid-Day Sessions
4 p.m. – 6 p.m.
12:15 p.m. – 1:15 p.m.
Certificate Exam Executive Committee Meeting
1:30 p.m. – 3:15 p.m.
Scientific Sessions/Symposia
Pre-Meeting Course Registration
Saturday, November 3
1:30 p.m. – 7 p.m.
Poster Session A Viewing
7 a.m. – 1:30 p.m.
3 p.m. – 4 p.m.
Exhibits Open
8:30 a.m. – 4:45 p.m.
Pre-Meeting Course: Systems Biology:
Approaches to Understanding Infectious Disease
3:15 p.m. – 3:45 p.m.
Break
Noon – 5 p.m.
Speaker Ready Room
Noon – 5 p.m.
Pre-Meeting Course: Chagas Disease (American
Trypanosomiasis): No Longer an Exotic Disease
Sunday, November 4
7 a.m. – 6 p.m.
Speaker Ready Room
7:30 a.m. – 3 p.m.
Pre-Meeting Course: Chagas Disease (American
Trypanosomiasis): No Longer an Exotic Disease
3:45 p.m. - 5:30 p.m.
6 p.m. – 6:45 p.m.
Plenary Session II: Soper Lecture
7 p.m. – 8 p.m.
Poster Session A Dismantle
7 p.m. – 9 p.m.
Late Breakers in Basic Science/Molecular Biology
7 p.m. – 9 p.m.
Late Breakers in Clinical Tropical Medicine
Tuesday, November 6
7 a.m. – 5 p.m.
Registration
Cyber Café
8 a.m. – 3:30 p.m.
ASTMH Council Meeting
7 a.m. – 5 p.m.
10:30 a.m. – 6 p.m.
Registration
7 a.m. – 6 p.m.
Speaker Ready Room
11 a.m. – 3:30 p.m.
Young Investigator Award Presentations
7 a.m. – 8 a.m.
Journal Editorial Board Meeting
11 a.m. – Noon
ACAV SIE Subcommittee Meeting
7 a.m. – 8 a.m.
Clinical Group Past Presidents Meeting
Noon – 2 p.m.
ACAV SIRACA Subcommittee Meeting
7 a.m. – 8 a.m.
Education Committee Meeting
1 p.m. – 6 p.m.
Cyber Café
8 a.m. – 9:45 a.m.
2 p.m. – 3:30 p.m.
ACAV SALS Subcommittee Meeting
9:30 a.m. – 10:30 a.m.
Exhibits Open
3:30 p.m. – 5 p.m.
Young Investigator Award Committee Meeting
9:45 a.m. – 10:15 a.m.
Poster Session B Setup
3:30 p.m. – 5 p.m.
ACME Council Meeting
9:45 a.m. – 10:15 a.m.
Break
3:30 p.m. – 5 p.m.
ACMCIP Council Meeting
10:15 a.m. – Noon
3:30 p.m. – 5:30 p.m.
ACAV Council Meeting
10:15 a.m. – Noon
Poster Session B Viewing (#391–620)
3:30 p.m. – 5:30 p.m.
Clinical Group Council Meeting
Noon – 3 p.m.
Exhibits Open
4 p.m. – 5 p.m.
Student Reception
Noon – 1:30 p.m.
Poster Session B Presentations/Light Lunch
5:30 p.m. – 7:30 p.m.
Opening Plenary Session and Awards Ceremony
12:15 p.m. – 1:15 p.m.
7:30 p.m. – 9:30 p.m.
Opening Reception
12:15 p.m. – 1:15 p.m.
CME/Courses Committee Meeting
7:30 p.m. – 9:30 p.m.
Exhibits Open
1:30 p.m. – 7 p.m.
Poster Session B Viewing
1:30 p.m. – 2:15 p.m.
Plenary Session III: Commemorative Fund Lecture
Monday, November 5
2:15 p.m. – 2:45 p.m.
Break
7 a.m. – 5 p.m.
Registration
2:45 p.m. – 4:30 p.m.
7 a.m. – 5 p.m.
Cyber Café
5 p.m. – 6:45 p.m.
7 a.m. – 6 p.m.
Speaker Ready Room
7 p.m. – 8 p.m.
Poster Session B Dismantle
7 a.m. – 8 a.m.
ASTMH Public Policy and Advocacy Leadership
Committee Meeting
7:15 p.m. – 9 p.m.
Evening Sessions
7 a.m. – 8 a.m.
Diploma Course Directors Meeting
Wednesday, November 7
7 a.m. – 8 a.m.
Meet the Professors: Fireside Chat
7 a.m. – 5 p.m.
Registration
8 a.m. – 9:45 a.m.
7 a.m. – 5 p.m.
Cyber Café
9:30 a.m. – 10:30 a.m.
Exhibits Open
7 a.m. – 6 p.m.
Speaker Ready Room
9:45 a.m. – 10:15 a.m.
Break
7 a.m. – 8 a.m.
ASTMH Past Presidents Meeting
9:45 a.m. – 10:15 p.m.
Poster Session A Setup
7 a.m. – 8 a.m.
Web Site Committee Meeting
10:15 a.m. – Noon
7 a.m. – 8 a.m.
Scientific Program Committee Meeting
10:15 a.m. – Noon
8 a.m. – 9:45 a.m.
Noon – 1:30 p.m.
Exhibits Open/Light Lunch
9:30 a.m. – 10:30 a.m.
Exhibits
Noon – 1:30 p.m.
Poster Session A Presentations (#57–299)
9:45 a.m. – 10:15 a.m.
Poster Session C Setup
Noon – 1:30 p.m.
Clinical Group Education Curriculum Committee
Meeting
9:45 a.m. – 10:15 a.m.
Break
6
www.astmh.org
Program Changes
The time and/or location of any activity or session is subject to change. Notices of program changes will be posted in the ASTMH registration area.
A Program Update is included in your registration packet.
10:15 a.m. – Noon
Poster Session C Viewing
10:15 a.m. – Noon
Noon – 2:30 p.m.
Exhibits Open
Noon – 1:30 p.m.
Poster Session C Presentations (#711–933)/
Light Lunch
Noon – 2 p.m.
Burroughs Wellcome Fund – ASTMH Fellowship
Committee Meeting
12:15 p.m. – 1:15 p.m.
12:15 p.m. – 1:15 p.m.
Certificate Exam Committee Meeting
1:30 p.m. – 3:15 p.m.
1:30 p.m. – 7 p.m.
3:15 p.m. – 3:45 p.m.
Break
3:45 p.m. – 5:30 p.m.
6 p.m. – 7:30 p.m.
Plenary Session IV: Presidential Address and
Annual Business Meeting
7 p.m. – 8 p.m.
Poster Session C Dismantle
Thursday, November 8
7 a.m. – 10:30 a.m.
Registration
7 a.m. – 10:30 a.m.
Cyber Café
7 a.m. – Noon
Speaker Ready Room
7:30 a.m. – 9:30 a.m.
8 a.m. – 9:45 a.m.
9:45 a.m. – 10:15 a.m.
Break
9:45 a.m. – Noon
Noon
Meeting Adjourns
7
www.astmh.org
Sunday, November 4
Salon E
7:00 a.m.
7:15 a.m.
7:30 a.m.
7:45 a.m.
8:00 a.m.
8:15 a.m.
8:30 a.m.
8:45 a.m.
9:00 a.m.
9:15 a.m.
9:30 a.m.
9:45 a.m.
10:00 a.m.
10:15 a.m.
10:30 a.m.
10:45 a.m.
11:00 a.m.
11:15 a.m.
11:30 a.m.
11:45 a.m.
12:00 p.m.
12:15 p.m.
12:30 p.m.
12:45 p.m.
1:00 p.m.
1:15 p.m.
1:30 p.m.
1:45 p.m.
2:00 p.m.
2:15 p.m.
2:30 p.m.
2:45 p.m.
3:00 p.m.
3:15 p.m.
3:30 p.m.
3:45 p.m.
4:00 p.m.
4:15 p.m.
4:30 p.m.
4:45 p.m.
5:00 p.m.
5:15 p.m.
5:30 p.m.
5:45 p.m.
6:00 p.m.
6:15 p.m.
6:30 p.m.
6:45 p.m.
7:00 p.m.
7:15 p.m.
7:30 p.m.
7:45 p.m.
8:00 p.m.
8:15 p.m.
8:30 p.m.
8:45 p.m.
9:00 p.m.
9:15 p.m.
9:30 p.m.
9:45 p.m.
10:00 p.m.
10:15 p.m.
Salon F
Salon G
Salon H
Independence I
Independence II
Independence III
Liberty A
Young
Investigator
Award A
p. 36
Young
Investigator
Award B
p. 38
Young
Investigator
Award C
p. 39
Young
Investigator
Award D
p. 41
Clinical
Pre-Meeting
Course
Young
Investigator
Committee
Meeting
Plenary I
Opening Lecture
Society Awards
p. 45
8
Sunday, November 4
Liberty C
7:00 a.m.
7:15 a.m.
7:30 a.m.
7:45 a.m.
8:00 a.m.
8:15 a.m.
8:30 a.m.
8:45 a.m.
9:00 a.m.
9:15 a.m.
9:30 a.m.
9:45 a.m.
10:00 a.m.
10:15 a.m.
10:30 a.m.
10:45 a.m.
11:00 a.m.
11:15 a.m.
11:30 a.m.
11:45 a.m.
12:00 p.m.
12:15 p.m.
12:30 p.m.
12:45 p.m.
1:00 p.m.
1:15 p.m.
1:30 p.m.
1:45 p.m.
2:00 p.m.
2:15 p.m.
2:30 p.m.
2:45 p.m.
3:00 p.m.
3:15 p.m.
3:30 p.m.
3:45 p.m.
4:00 p.m.
4:15 p.m.
4:30 p.m.
4:45 p.m.
5:00 p.m.
5:15 p.m.
5:30 p.m.
5:45 p.m.
6:00 p.m.
6:15 p.m.
6:30 p.m.
6:45 p.m.
7:00 p.m.
7:15 p.m.
7:30 p.m.
7:45 p.m.
8:00 p.m.
8:15 p.m.
8:30 p.m.
8:45 p.m.
9:00 p.m.
9:15 p.m.
9:30 p.m.
9:45 p.m.
10:00 p.m.
10:15 p.m.
www.astmh.org
(continued)
Porthole Room
Across Bridge
Room 301
Rooms
305-306
Room 309
Room 362
Room 405
ACMCIP
Council
Meeting
Clinical
Group
Council
ASTMH
Council
Meeting
Young
Investigator
Award E
p. 43
ACAV
SIE
ACAV
SIRACA
ACAV
SALS
Student
Reception
ACME
Council
Meeting
ACAV
Council
Meeting
9
www.astmh.org
Monday, November 5
Franklin Hall B
7:00 a.m.
7:15 a.m.
7:30 a.m.
7:45 a.m.
8:00 a.m.
8:15 a.m.
8:30 a.m.
8:45 a.m.
9:00 a.m.
9:15 a.m.
9:30 a.m.
9:45 a.m.
10:00 a.m.
10:15 a.m.
10:30 a.m.
10:45 a.m.
11:00 a.m.
11:15 a.m.
11:30 a.m.
11:45 a.m.
12:00 p.m.
12:15 p.m.
12:30 p.m.
12:45 p.m.
1:00 p.m.
1:15 p.m.
1:30 p.m.
1:45 p.m.
2:00 p.m.
2:15 p.m.
2:30 p.m.
2:45 p.m.
3:00 p.m.
3:15 p.m.
3:30 p.m.
3:45 p.m.
4:00 p.m.
4:15 p.m.
4:30 p.m.
4:45 p.m.
5:00 p.m.
5:15 p.m.
5:30 p.m.
5:45 p.m.
6:00 p.m.
6:15 p.m.
6:30 p.m.
6:45 p.m.
7:00 p.m.
7:15 p.m.
7:30 p.m.
7:45 p.m.
8:00 p.m.
8:15 p.m.
8:30 p.m.
8:45 p.m.
9:00 p.m.
9:15 p.m.
9:30 p.m.
9:45 p.m.
10:00 p.m.
10:15 p.m.
Franklin Hall B
Salon AB
Salon CD
Salon E
Salon F
Salon G
Salon H
2 Meet the Profs A
Career Dev/Clin
Trop Med
p. 46
Symposium
2A
Symposium
3
Artemether
Vector Borne
Lumefantrine Peds Surveillance and
p. 46
Control
p. 47
Exhibits Open
Coffee Break
9:30-10:30 a.m.
Symposium
5
Ethics Research
p. 52
ACMCIP Host
Pathogen
Genomics
p. 47
Scientific
Session
6
Flavivirus I
Dengue I
p. 48
Symposium
7
NTDs
p. 48
Poster Session A
Set-Up
Poster
Session A
Viewing
Exhibit Hall
Open
Symposium
13
Poster
Session A
Light Lunch
p. 61
Poster
Session A
Viewing
Symposium
14
Symposium
15
Symposium
16
Symposium
17
Malaria Genetic
Diversity
p. 53
Vectors and
Bacterial EIDs
p. 53
Trypanasomatid
Host-Parasite
p. 54
Vivax Malaria
p. 54
27 Mid-Day
Migrant Health
p. 83
28 Mid-Day
Travel Med:
Chronic Conditions
p. 83
Symposium
33
Symposium
34
Dx in Tropics
p. 85
Trypanosomatid
Parasite Bio
p. 86
Symposium
43
Scientific
Session
44
Scientific
Session
45
Kinetoplastida I:
Immuno Mol Bio
p. 91
Malaria
Immunology II
p. 92
Scientific
Session
18
Flavivirus II
Dengue II
p. 54
Symposium
19
Scaling up ACTs
p. 55
29 Career
Development
Global Health
p. 84
Scientific
Session
35
Malaria
Immunology I
p. 86
Symposium
36
Symposium
37
Symposium
38
ACME I
p. 87
Chagas
p. 88
Trachoma
p. 88
Exhibits Open
Coffee Break
3:15-3:45 p.m.
M(X)DR TB
p. 91
Symposium
46
ACME II
p. 93
Plenary II
Soper Lecture
p. 97
Poster
Session A
Dismantle
Late Breakers
Clinical Tropical
Medicine
p. 97
Late Breakers
Basic Science
Molecular Bio
p. 97
10
Monday, November 5
7:00 a.m.
7:15 a.m.
7:30 a.m.
7:45 a.m.
8:00 a.m.
8:15 a.m.
8:30 a.m.
8:45 a.m.
9:00 a.m.
9:15 a.m.
9:30 a.m.
9:45 a.m.
10:00 a.m.
10:15 a.m.
10:30 a.m.
10:45 a.m.
11:00 a.m.
11:15 a.m.
11:30 a.m.
11:45 a.m.
12:00 p.m.
12:15 p.m.
12:30 p.m.
12:45 p.m.
1:00 p.m.
1:15 p.m.
1:30 p.m.
1:45 p.m.
2:00 p.m.
2:15 p.m.
2:30 p.m.
2:45 p.m.
3:00 p.m.
3:15 p.m.
3:30 p.m.
3:45 p.m.
4:00 p.m.
4:15 p.m.
4:30 p.m.
4:45 p.m.
5:00 p.m.
5:15 p.m.
5:30 p.m.
5:45 p.m.
6:00 p.m.
6:15 p.m.
6:30 p.m.
6:45 p.m.
7:00 p.m.
7:15 p.m.
7:30 p.m.
7:45 p.m.
8:00 p.m.
8:15 p.m.
8:30 p.m.
8:45 p.m.
9:00 p.m.
9:15 p.m.
9:30 p.m.
9:45 p.m.
10:00 p.m.
10:15 p.m.
www.astmh.org
(continued)
Salon IJ
Salon KL
Liberty AB
Liberty C
Symposium
8
Symposium
9
Symposium
10
Scientific
Session
11
HIV in Tropics
p. 49
Cystic
Echinococcosis
p. 49
Tropical Med
and Media
p. 49
Symposium
20
Scientific
Session 21
Scientific
Session
22
Scientific
Session
23
Schistosoma
Japonica
p. 56
Helminths I
Cestodes
p. 56
Malaria Vector Bio
p. 57
Malaria
Vaccines II
p. 58
Franklin 1
Franklin 3/4
Scientific
Session 12
Bacteriology I
Diarrhea Enteric
Infections
p. 51
Malaria
Vaccines I
p. 50
Symposium
24
Scientific
Session 25
Symposium
26
Filarial Genomics Bacteriology II H2O, Research, Ethics
p. 59
and Obligations
Treatment and
p. 60
Diarrhea
p. 60
31 Mid-Day
Chagas Movie
p. 84
30 Mid-Day
Tropical
Radiology p. 84
Franklin 2
Symposium
39
Symposium
40
Symposium
41
Zoonoses
p. 88
Mosquito
Repellents
p. 89
Malaria Control
Programs Africa
p. 89
Symposium
47
Symposium
48
Symposium
49
Symposium
50
Malaria
Transmission
JHMRI
p. 93
Fascioliasis
p. 93
Malaria MMV Rx
Portfolio
p. 94
Outbreak
Reporting
p. 94
32 Mid-Day
ASTMH Journal
p. 84
32A
Meet the Profs B
Enigmatic Cases
p. 85
Scientific
Session
42
Schistosomiasis I
Imm/Para Dev
p. 90
11
Scientific
Session
51
Scientific
Session
52
Bacteriology III
p. 95
Schistosomiasis II
Epi
p. 96
www.astmh.org
Tuesday, November 6
Franklin Hall B
7:00 a.m.
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Exhibits Open
Coffee Break
9:30-10:30 a.m.
Franklin Hall B
Salon AB
Salon CD
Salon E
Salon F
Salon G
Salon H
Symposium
54
Symposium
55
Symposium
56
Scientific
Session
57
Symposium
58
Scientific
Session
59
ArtemetherLumefantrine
p. 98
Malaria
Signaling
p. 98
Protozoa and
Serum
Proteomics
p. 98
Flavivirus III
Dengue III
p. 99
Scientific
Session
67
Symposium
68
Symposium
69
Global Health
Youth
Investigator
p. 106
ACT: Africa
p. 107
Malaria Dx
p. 100
Symposium
70
Symposium
71
Symposium
72
ACAV
p. 108
Antimalarial
Resistance
Network
p. 108
Tropical
Dermatology
p. 109
Poster Session B
Set-Up
Poster
Session B
Viewing
Malaria
Molecular Biology
p. 105
Exhibits
Open
Remote Sensing
Vector Borne
p. 100
Poster
Session B
Light Lunch
p. 113
78 Mid-Day
Bioinformatics
Trop Med NCBI
p. 134
79 Trainee Lunch
79A
with ASTMH Ed. Climate Change
Committee
and Global Health
p. 134
p. 135
Poster
Session B
Viewing
Exhibits Open
Coffee Break
2:15-2:45 p.m.
Plenary III Commemorative Fund
Lecture p. 136
Symposium
83
VHF Plasma
Leakage
p. 136
Symposium
93
Falciparum
Recurrence
p. 141
Poster
Session B
Dismantle
Scientific
Session
84
Mosquitoes: Vector
Bio/Epi I
p. 136
Scientific
Session
94
Mosquitoes: Vector
Bio/Epi. II
p. 142
103 Meet the
Profs D Career
Mentoring
p. 147
12
Symposium
85
Clinical Group I
p. 137
Symposium
95
Clinical Group II
p. 142
104 Malaria
Post-Genomics
p. 148
Scientific
Session
86
ACMCIP Cellular
Parasitology I
p. 138
Scientific
Session
96
ACMCIP Cellular
Parasitology II
p. 143
Symposium
97
Symposium
98
AMA-1 Malaria
Vaccine Trials
p. 144
Echinococcus
Host-Parasite
p. 144
104A
Chagas Movie
p. 148
Tuesday, November 6
7:00 a.m.
7:15 a.m.
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www.astmh.org
(continued)
Salon IJ
Salon KL
Liberty AB
Liberty C
Franklin 1
Franklin 2
Franklin 3/4
Symposium
60
Symposium
61
Scientific
Session
62
Scientific
Session
63
Symposium
64
Symposium
65
Symposium
66
Rural 2nd
Health Care
p. 101
Leishmaniasis:
Field and Rx
p. 102
Clinical Trop
Med I
p. 102
Filariasis I:
Epi/Mol Bio
p. 103
Gut Parasites
Immune
Regulation
p. 104
Vector Control
Africa Costing
p. 104
Schistosomiasis
Operational
Research
p. 105
Scientific
Session
73
Symposium
74
Scientific
Session
75
Scientific
Session
76
Clinical
Trop Med II
p. 110
Filariasis II
Chemotherapy
p. 111
Helminths II
Echinococcus
p. 109
Memory T Cell
Parasites
p. 110
80 Mid-Day
Malaria
Simulation
Modeling p. 135
Symposium
77
Anopheline AntiMalaria Defense
p. 112
81 Meet the Profs
C Effective Talks
p. 135
Symposium
87
Symposium
88
Cerebral Malaria
Signaling
p. 138
Schistosomiasis
Burden
p. 139
Symposium
99
Symposium
100
Helminths Effects
p. 145
Antimalarial
Access
p. 145
Scientific
Session
89
Malaria
Chemotherapy
p. 139
82 Mid-Day
Travelers’ Malaria
Prevention
p. 135
Symposium
90
Symposium
92
Sandfly Genomics
p. 140
Macrophages/
Helminths
p. 141
Scientific
Session
101
Symposium
102
JE Vaccine:
Socio-Political
p. 147
Malaria Drug
Development
p. 146
13
www.astmh.org
Franklin Hall B
7:00 a.m.
7:15 a.m.
7:30 a.m.
7:45 a.m.
8:00 a.m.
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9:30 p.m.
9:45 p.m.
10:00 p.m.
10:15 p.m.
Exhibits Open
Coffee Break
9:45-10:15 a.m.
Franklin Hall B
Salon AB
Salon CD
Salon E
Salon F
Salon G
Salon H
Symposium
105
Symposium
106
Symposium
107
Scientific
Session
108
Scientific
Session
109
Scientific
Session
110
Heterogeneity and
Mosquito Borne
p. 148
Isolation of
Artemisinin
p. 149
One Medicine:
One Health
p. 149
Symposium
117
Symposium 118
Symposium
119
Malaria Epi I
p. 151
Poster Session C
Set-Up
Poster Session C
Viewing
Global Enteric
Multi-Center Study
p. 156
Exhibits
Open
Flavivirus IV West ACMCIP ImmunoNile Virus
parasitology I
p. 150
p. 151
Poster Session C
Light Lunch
Poster Session C
Viewing
Launch Careers
BWF/ASTMH
and FIC Fellow
Updates
p. 157
Trop Med
Diagnostics
p. 157
129 Global Health
Careers
p. 184
Scientific
Session
120
Scientific
Session
121
Scientific
Session
122
Flavivirus V
p. 158
ACMCIP Immunoparasitology II
p. 158
Malaria Epi II
p. 159
130 Mid-Day Pub
Med and HINARI
p. 185
131 Mid-Day
Scientists
Making Media
p. 185
Symposium
135
Symposium
136
Scientific
Session 137
Symposium
138
Symposium
138A
Symposium
139
RVF Kenya I
p. 186
NTDs Vaccines
p. 187
Malaria Drug
Resistance Modeling +
High Throughput
Analysis
p. 187
Malaria and
Gender
p. 188
VFR
p. 188
Dengue Vaccine
Development
p. 189
Symposium
145
Scientific
Session
146
Scientific
Session 147
Symposium
148
Malaria Mol
Markers Drug
Resistance
p. 194
RTS,S Malaria
Vaccine
p. 195
Coffee Break
RVF Kenya II
p. 193
Protozoa
p. 193
Plenary IV
President’s Address
p. 200
Poster Session C
Dismantle
14
7:00 a.m.
7:15 a.m.
7:30 a.m.
7:45 a.m.
8:00 a.m.
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www.astmh.org
(continued)
Salon IJ
Salon KL
Liberty AB
Liberty C
Symposium
111
Symposium
112
Symposium
113
Antiparasitic Drug
Models
p. 152
Population
Surveillance
p. 153
Symposium
123
Schistosomiasis
New Drug/Targets
p. 160
Franklin 2
Franklin 3/4
Symposium
114
Scientific Session
115
Symposium
116
Leishmaniasis Rx
and PKDL
p. 153
IPT Children
Malaria
p. 154
Pneumonia and
ARIs
p. 154
Poor Quality
Anti-Malarials
p. 155
Symposium
124
Symposium
125
Symposium
126
Symposium
126A
Symposium
127
Scientific
Session
128
Militaries and
Public Health
Surveillance
p. 161
Strongyloidiasis
p. 161
IPTi Update
p. 162
Vaccine Adjuvants
p. 162
Malaria Drug
Resistance
Pathogenesis
p. 163
132 Mid-Day
Grants/NIH
Funding
p. 185
Franklin 1
132A Mid-Day
Workers in Trop
Med Karl Johnson
p. 185
HIV in Tropics
p. 163
133 Meet the
Profs E Travel to
Give or Receive
Care p. 186
Scientific Session
140
Symposium
141
Symposium
142
Scientific Session
143
Mosquito
Biochem Mol Bio
Genetics I
p. 189
Schistosome
Genomics
p. 190
Leishmania
Vaccines,
Immuno Rx
p. 190
Filariasis III
Immunology
p. 191
Symposium
151
Symposium
152
Symposium
153
Symposium
154
Scientific Session
155
Leishmaniasis:
Post-Genome
p. 197
Filariasis
Elimination
p. 198
Arboviral
Emergence
p. 198
Integrated Vector
Control Africa
p. 199
Viruses II
p. 199
Scientific Session Scientific Session
149
150
Mosquito Biochem
Mol Bio Genetics II
p. 196
Helminths III:
Nematodes
p. 196
15
Scientific
Session
144
Viruses I
p. 191
www.astmh.org
Franklin Hall
Foyer
7:00 a.m.
7:15 a.m.
7:30 a.m.
7:45 a.m.
8:00 a.m.
8:15 a.m.
8:30 a.m.
8:45 a.m.
9:00 a.m.
9:15 a.m.
9:30 a.m.
9:45 a.m.
10:00 a.m.
10:15 a.m.
10:30 a.m.
10:45 a.m.
11:00 a.m.
11:15 a.m.
11:30 a.m.
11:45 a.m.
12:00 p.m.
12:15 p.m.
12:30 p.m.
12:45 p.m.
Salon CD
Salon E
Salon F
Salon G
Salon H
Scientific
Session
157
Symposium
158
Scientific
Session
159
Symposium
160
Scientific
Session
161
Scientific Session
162
Kinetoplastida II
Epi/Dx/Rx
p. 201
CD8 and Parasites
p. 202
Clinical Trop
Med III
p. 202
JE Updates
p. 203
ACMCIP Molecular
Parasitology I
p. 204
Malaria Bio and
Pathogenesis
p. 204
Coffee Break
Scientific
Session
165
Scientific
Session
166
Schistosomiasis III
Mosquitoes:
Mol Bio
Vector Bio III Epi
p. 207
p. 207
Salon IJ
7:00 a.m.
7:15 a.m.
7:30 a.m.
7:45 a.m.
8:00 a.m.
8:15 a.m.
8:30 a.m.
8:45 a.m.
9:00 a.m.
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9:30 a.m.
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10:00 a.m.
10:15 a.m.
10:30 a.m.
10:45 a.m.
11:00 a.m.
11:15 a.m.
11:30 a.m.
11:45 a.m.
12:00 p.m.
12:15 p.m.
12:30 p.m.
12:45 p.m.
Salon AB
Salon KL
Room 303
Scientific
Session
167
Clinical Trop
Med IV
p. 208
Room 304
Scientific
Session
163
Arthropods
Entomology
p. 205
Scientific
Session
171
Ectoparasite
Borne Diseases
p. 211
Symposium
164
Larval Source
Management I
p. 206
Symposium
172
Larval Source
Management II
p. 212
16
Symposium
168
Viral Vector
Variation
p. 209
Scientific
Session
169
Scientific
Session
170
ACMCIP Molecular
Parasitology II
p. 209
Malaria Bio and
Pathogenesis II
p. 210
Affiliate Group Meeting Schedule
Liverpool School of
Tropical Medicine IVCC
ESAC LIGHT
Room 336
9 a.m. – 5 p.m.
NIH/Fogarty International
Center GID Network
Meeting
Room 407-408
9 a.m. – 5 p.m.
Department of Defense
Global Emerging
Infections System
Malaria Meeting
Room 304
9 a.m. – 6 p.m.
MR4 Science Advisory
Committee Meeting
Room 304
11 a.m. – 4 p.m.
GeoSentinel Site
Directors Meeting
Room 411
1 p.m. – 5 p.m.
Liverpool School of
Tropical Medicine AWOL
Management Meeting
Room 336
1 p.m. – 6 p.m.
Monday, November 5
Sunday, November 4
sanofi aventis
Conference Room
Room 301
8 a.m. – 9 p.m.
Liverpool School of
Tropical Medicine
AWOL Consortium
Room 303
8 a.m. – 2 p.m.
Medicines for
Malaria Venture
Conference Room
Room 412
8 a.m. – 5 p.m.
Medicines for
Malaria Venture
Conference Room
Room 412
8 a.m. – 5 p.m.
GlaxoSmithKline
Conference Room
Room 411
8 a.m. – 5 p.m.
Novartis
Conference Room
Room 502
9 a.m. – 5 p.m.
Liverpool School of
MDSS Review
Room 406
9 a.m. – 4 p.m.
MIM/TDR Meeting
Room 304
9 a.m. – 11 a.m.
Bill & Melinda Gates
Foundation Side
Meetings
Room 302
9 a.m. – 5 p.m.
Foundation Vector
Control Meeting
Room 301
9 a.m. – 3 p.m.
Medicines for Malaria
Venture Drug
Combination Science
Meeting
Salon IJ
10 a.m. – 4 p.m.
Novartis
Conference Room
Room 502
9 a.m. – 8 p.m.
Foundation Side
Meetings
Room 302 and 405
9 a.m. – 5 p.m.
Institute for OneWorld
Health Meetings
Room 406
9 a.m. – 5 p.m.
Foundation TBV Project
Room 305
10 a.m. – 1 p.m.
Novartis Steering
Committee Meeting
Independence I
Noon – 3:30 p.m.
GlaxoSmithKline
Meeting Room
Room 410
1 p.m. – 5 p.m.
Sabin Vaccine Institute
Global Network for
Neglected Tropical
Diseases Partners
Meeting
Room 305
3 p.m. – 5 p.m.
PATH MVI – Crucell
Meeting
Room 306
3 p.m. – 7 p.m.
London School of
Hygiene and Tropical
Medicine Alumni
Reception
Liberty C
7 p.m. – 9 p.m.
Novartis Investigators
Meeting
Independence I
5 p.m. – 6:30 p.m.
Public Library of Science
Neglected Tropical
Diseases Editorial
Board Meeting
Room 304
7 p.m. – 9 p.m.
PATH MVI AMA
Investigators Meeting
Room 305–306
7 p.m. – 9 p.m.
Health Reception
Liberty C
7:15 p.m. – 10 p.m.
Tuesday, November 6
Global TravEpiNet
Meeting
Room 305
7 a.m. – 8 a.m.
Medicines for
Malaria Venture
Conference Room
Room 412
8 a.m. – 5 p.m.
GlaxoSmithKline
Meeting Room
Room 502
8 a.m. – Noon
sanofi aventis
Conference Room
Room 301
8 a.m. – 5 p.m.
GlaxoSmithKline
Conference Room
Room 411
8 a.m. – 5 a.m.
IPTi Executive
Committee Meeting
Room 306
8:30 a.m. – 2:30 p.m.
Foundation Side
Meetings
Room 302 and 405
9 a.m. – 5 p.m.
Health Meetings
Room 406
9 a.m. – 5 p.m.
Biomphalaria Glabrata
Genome Initiative
Salon KL
12:15 p.m. – 1:15 p.m.
17
GlaxoSmithKline
Conference Room
Room 411
8 a.m. – 5 p.m.
Medicines for
Malaria Venture
Conference Room
Room 412
8 a.m. – 5 p.m.
Health Meetings
Room 406
9 a.m. – 5 p.m.
Foundation Side
Meetings
Room 302 and 405
9 a.m. – 5 p.m.
MIM Strategic Advisory
Board Meeting
Room 502
10 a.m. – 3:30 p.m.
Pediatric Dengue
Vaccine Initiative
Management/Finance
Committee Meeting
Room 303
6 p.m. – 10 p.m.
TDR/WHO
Miltefosine Product
Development Team
Room 410
7 p.m. – 10 p.m.
www.astmh.org
Foundation Integration
Grants Meeting
Room 502
8 a.m. – 5 p.m.
Medicines for
Malaria Venture
Conference Room
Room 412
8 a.m. – 5 p.m.
GlaxoSmithKline/WRAIR
Dengue Project Team
Room 411
8 a.m. – 6 p.m.
Foundation Side
Meetings
Room 302 and 405
9 a.m. – 5 p.m.
Health Meetings
Room 406
9 a.m. – 5 p.m.
Pediatric Dengue
Vaccine Initiative
Board of Counselors
Annual Meeting
Room 305
9 a.m. – 9 p.m.
Liverpool School of
Objective Two Meeting
Room 309
Noon – 5 p.m.
Friday, November 9
Foundation Integration
Grants Meeting
Room 502
8 a.m. – 5 p.m.
MVI/GlaxoSmithKline
Partnership/Steering
Committee
Room 415
9 a.m. – 5 p.m.
Pediatric Dengue
Vaccine Initiative
Board of Counselors
Annual Meeting
Room 305
9 a.m. – 9 p.m.
NOTE: Affiliate group meetings
are by invitation only.
ASTMH Council, Committee and Subgroup Meetings
Sunday, November 4
Tuesday, November 6
Rooms 305-306
8 a.m. – 3 p.m.
Room 306
7 a.m. – 8 a.m.
American Committee on Arthropod-Borne Viruses (ACAV) SIE
Subcommittee
Room 309
11 a.m. – Noon
www.astmh.org
Room 410
7 a.m. – 8 a.m.
American Committee on Arthropod-Borne Viruses (ACAV) SIRACA
Subcommittee
Room 309
Noon – 2 p.m.
Journal Editorial Board Meeting
Room 309
7 a.m. – 8 a.m.
Room 336
12:15 p.m. – 1:15 p.m.
American Committee on Arthropod-Borne Viruses (ACAV) SALS
Subcommittee
Room 309
2 p.m. – 3:30 p.m.
American Committee on Arthropod-Borne Viruses (ACAV)
Council Meeting
Room 309
3:30 p.m. – 5:30 p.m.
Room 305
7 a.m. – 8 a.m.
Room 362
7 a.m. – 8 a.m.
American Committee of Medical Entomology (ACME) Council Meeting
Room 301
3:30 p.m. – 5 p.m.
Rooms 303-304
7 a.m. – 8 a.m.
American Committee of Molecular, Cellular and Immunoparasitology
(ACMCIP) Council Meeting
Room 362
3:30 p.m. – 5 p.m.
Burroughs Wellcome Fund — ASTMH Fellowship Committee Meeting
Room 336
Noon – 2 p.m.
Room 405
3:30 p.m. – 5:30 p.m.
Room 410
12:15 p.m. – 1:15 p.m.
Young Investigator Award Committee Meeting
Independence I
3:30 p.m. – 5 p.m.
Rooms 303-304
7:30 a.m. – 9:30 a.m.
Monday, November 5
ASTMH Public Policy and Advocacy Leadership Committee Meeting
Room 305
7 a.m. – 8 a.m.
Committee Meetings
Room 410
7 a.m. – 8 a.m.
Rooms 303 and 304 on the third floor are designated for committee meetings and other group meetings. Meeting room reservations are available on
a first-come, first-served basis. Use the sign-up sheets located outside these
rooms to reserve meeting time for your group.
Clinical Group Education Curriculum Committee Meeting
Room 336
Noon – 1:30 p.m.
Certificate Exam Executive Committee Meeting
Room 362
12:15 p.m. – 1:15 p.m.
ASTMH Subgroup Tables
Visit the American Committee of Medical Entomology (ACME)
and the American Committee on Arthropod-Borne Viruses
(ACAV) information tables in the exhibit hall to learn about their
programs and activities.
19
www.astmh.org
ASTMH 56th Annual Meeting
Officers
President
Carlos C. (Kent) Campbell
President-Elect
Claire Panosian
Immediate Past President
Myron (Mike) Levine
Secretary-Treasurer
George Hillyer
Executive Director
Sally Finney
Councilors
John Donelson
Regina Rabinovich
Frank Richards
Carol Hopkins Sibley
Scott Weaver
Gary Weil
Clinton White
Mary Wilson
Chair, Scientific Program Committee
Edward Ryan
Editor, American Journal of Tropical Medicine and Hygiene
James Kazura
Editors, Tropical Medicine and Hygiene News
William Collins and Geoffrey Jeffery
Web Site Editor
Jack Woodall
Advisor
Peter Weller
60 Revere Drive, Suite 500
Northbrook, IL 60062 USA
847/480-9592
Fax: 847/480-9282
info@astmh.org
www.astmh.org
20
Scientific Program Committee
www.astmh.org
Edward T. Ryan, Chair
Career Development/Education
Chair: Sarah Volkman
Michele Barry
Steve Higgs
Anne McCarthy
Clinical Tropical Medicine
Chair: Alan Magill
Robert Gasser
Davidson Hamer
Larry Laughlin
Alan Spira
Marty Wolfe
David McNeeley
Joe Vinetz
Diarrhea and Bacterial Illness
Chair: Edward T. Ryan
Davidson Hamer
James Hughes
Regina LaRocque
Pavani Ram
Entomology
Chair: William Black
Kate Aultman
Hilary Ranson
David Severson
Filariasis
Chair: Amy Klion
Edward Mitre
Frank Richards
Steven Williams
Intestinal and Tissue Helminths, Cestodes
Chair: A. Clinton White
David Abraham
Mark Eberhard
Peter Kern
Kinetoplastida
Chair: Rick Tarleton
Barbara Burleigh
Diane McMahon-Pratt
Opportunistic and Anaerobic Protozoa
Chair: Thaddeus Graczyk
Barbara Mann
Upinder Singh
David McNeeley
Barbara Herwaldt
Pneumonia and Respiratory Illness
Chair: Abdullah Brooks
Davidson Hamer
Keith Klugman
Late Breakers in Molecular Biology
Stefan Kappe
Rebeca Rico-Hesse
Malaria
Chair: Carol Sibley
Jeanne Courval
Johanna Daily
Mary Hamel
Sanjai Kumar
Miriam Laufer
Christopher Plowe
Laurence Slutsker
Joe Vinetz
Sarah Volkman
Kim Williamson
Yimin Wu
Schistosomiasis-Helminths
Chair: W. Evan Secor
Miguel Stadecker
David Williams
Tom Wynn
Tick-Louse-Flea-Mite-Borne Diseases
Chair: Stephen Dumler
Bob Lane
Sam Telford
Tropical HIV
Chair: Jean Nachega
Davidson Hamer
Rocio Hurtado
Meet the Professors
Anne McCarthy
Molecular Parasitology
Chairs: Michael Cappello/Sarah Volkman
David Abraham
John Adams
Barbara Burleigh
Daniel Carucci
Brian Cooke
Donald Harn
Stuart Kahn
Peter Kima
Beth Kirkpatrick
Barbara Mann
Diane McMahon-Pratt
Peter Melby
Evan Secor
Joe Vinetz
Sarah Volkman
David Williams
Kim Williamson
Tom Wynn
21
Virology
Chair: Rebeca Rico-Hesse
Carol Blair
Scott Halstead
George Ludwig
Julia Lynch
Michael Turell
www.astmh.org
ASTMH Committees and Subgroups
Archives
Chair: Donald Burke
Editorial Board, American Journal of Tropical Medicine and Hygiene:
David Abraham; John Barnwell; Michael Cappello; William Collins; Hector
Garcia; James Hughes; Jay Keystone; Philip Loverde; Steven Meshnick;
Thomas Nutman; Rebeca Rico-Hesse; Philip Rosenthal; Frank Sorvillo;
Andrew Spielman; Terrie Taylor; Robert Tesh; David Walker; Editorial Staff:
James Kazura, Chair (Editor-in-Chief); McWilson Warren (Emeritus Editor);
Joe Vinetz (Associate Editor); Cathi Siegel (Managing Editor); Laura Buckley
(Editorial Assistant); Allen W. Hightower (Statistical Editor); Section Editors: J.
Kevin Baird; J. Stephen Dumler; Hisashi Fujioka; Diane McMahon-Pratt; Scott
C. Weaver; Clinical Group Editor: Jamie Maguire.
Audit
Chair: George Hillyer
Stephen Hoffman; Dyann Wirth
Awards
Chair: Peter Weller (2005-2007)
Thomas Monath (2006-2008); Myron Levine (2007-2009)
Benjamin H. Kean Traveling Fellowship in Tropical Medicine
Chair: Christopher Plowe
Alberto Acosta; Frank Bia; Stephen Hoffman; Colette Kean; Myaing Nyunt;
Martin Wolfe
Education:
Chair: Stephen Higgs
Noah Craft; Hector Gorbea; Laura Harrington; Risa Hoffman; Charles
McGee; Victoria McGovern; Claire Panosian; Sarah Volkman; Steve Wikel;
Jack Woodall (ad hoc); Peter Zimmerman
Bioterrorism
Chair: Daniel Carucci
Carter Diggs; James Hughes; George Korch
Fundraising:
Chair: Peter Weller
Michele Barry; Stephen Hoffman; Peter Hotez; James Kazura; Tom Monath;
William Petri; Dyann Wirth
Burroughs Wellcome Fund-ASTMH Fellowship
Chair: Terrie Taylor
Stephen Calderwood; Ravi Durvasula; Richard Guerrant; Victoria McGovern;
Claire Panosian
Gorgas Memorial Institute Research Award
Chair: Rebeca Rico-Hesse
Rodney Adam; Kathryn Aultman; Ynes Ortega
Certificate Examination
Chair: Susan McLellan
Lin Chen; Jovita Fernandez; David Freedman; Gregory Juckett; Lisa Keep; Ali
Khan; Victor Kovner; Walter Kuhn; Jamie Maguire; Bonnie Smoak; William
Stauffer; A. Clinton White
Honorary Membership
Chair: Richard Guerrant
John David; Thomas Monath; Frank Neva
International Federation of Tropical Medicine Representative
Don Krogstad
Certificate Exam Executive Committee
Chair: Jamie Maguire
Kent Campbell (2007); George Hillyer (2006-2008); Patricia Joyce (20072009); Larry Laughlin; Anne McCarthy (2007); Susan McLellan (2007-2009)
Lecture (Fred L. Soper and Charles F. Craig)
Chair: Robert Tesh
Donald Burke; David Freedman (Gorgas representative); Peter Hotez;
William Petri
Commemorative Fund Lectureship
Chair: Kent Campbell (2007)
Communications Award
Chair: Claire Panosian
Jon Cohen, David Hill, Susan Okie, Mary Wilson
Membership
Chair: George Hillyer
Stephen Higgs; Anne McCarthy; Claire Panosian; Sarah Volkman; Doug
Watts
Continuing Medical Education
Chair: Jonathan Berman
David Hill; Elaine Jong; Kevin Kain; Alan Magill; Edward Ryan
Newsletter Editorial Board
William Collins, Editor; Geoffrey Jeffery, Editor
Kate Aultman; Latha Rajan; Mitzi Sereno; Karl Western
Corporate Liaison
Chair: Thomas Monath
Bradley Connor; Jeff Chulay; Adel Mahmoud; Jaco Smit
Nominations
Chair: Mike Levine (2007)
Nora Besansky (2007-2008); Mark Eberhard (2007-2008); Gray Heppner
(2006-2007); Anthony James (2006-2007); Alan Magill (2007-2008);
Barbara Mann (2006-2007); Julie Moore (2007-2008); Elizabeth Nardin
(2006-2007); Claire Panosian (2007-2008); Mark Wilson (2006-2007)
Courses Committee
Chair: Alan Magill
Jonathan Berman; David Hill; Elaine Jong; Kevin Kain; Edward Ryan
Pfizer Centennial Travel Award
Chair: Joe Vinetz
John Adams; Barbara Burleigh; Michael Cappello; Diane McMahon-Pratt
Credentialing Committee
Chair: Larry Laughlin
David Freedman; David Hill; Christopher Karp; Jay Keystone; Christopher
King; Herbert Tanowitz
Program Certification
Chair: Jamie Maguire
Michele Barry; David Freedman; Richard Guerrant; Rocio Hurtado; James
Kazura; Donald Krogstad; Larry Laughlin; Anne McCarthy; Alan Spira;
Peter Weller
Current Affairs
Chair: Richard Guerrant
Joseph Cook; Jacob Frenkel; Scott Halstead
22
www.astmh.org
Public Policy and Advocacy Leadership Committee
Chair: Kent Campbell
Michele Barry; Frank Collins; Stephen Hoffman; Peter Hotez; Alan Magill;
Tom Monath; Claire Panosian; Frank Richards; Larry Slutsker; Terrie Taylor
Robert E. Shope International Fellowship
Chair: Charles Calisher
Barry Beaty; Donald Burke; George Ludwig; Barry Miller; Philip Russell;
Richard Shope; Peter Weller
Scientific Program
Chair: Edward T. Ryan (2005-2007)
ASTMH Headquarters Staff
Travel Awards Committee
Chair: James LeDuc
Mark Eberhard; Jamie Maguire; Dan Milner; Terrie Taylor; Eileen Villasante;
Joe Vinetz
Sally Finney
Executive Director
Judy DeAcetis
Administrative Director
Update Course in Clinical Tropical Medicine and Travelers’ Health
Co-Chairs: Alan Magill and Richard Pearson
Buffy Finn
Membership Services Administrator
Web Site Committee
Chair: Ken Dardick
Kathryn Aultman; Stephen Cunnion; Akhil Vaidya; Dawn Wesson;
Jack Woodall
Lyn Maddox
Conference Director
Kim Santos
Conference Administrator
Young Investigator Award
Chair: Peter Zimmerman
Kathryn Aultman; Subbaraman Babu; Brenda Beerntsen; Roland Cooper;
Stephen Davies; Christopher King; Sanjai Kumar; Nick Komar; Miriam
Laufer; Julian Rayner; W. Evan Secor; Daniel Tisch; Joe Vinetz; Patty Wilkins;
David Williams; Yimin Wu
Madhuri Carson
Conference Administrator
Matthew Lesh
Communications Manager
Jill Hronek
Communications Director
American Committee of Medical Entomology (ACME)
Chair: Stephen Higgs
Scott Taylor
Accountant
American Committee on Arthropod-Borne Viruses (ACAV)
Chair: Douglas Watts
Clinical Group (American Committee on Clinical Tropical Medicine and
Travelers’ Health – ACCTMTH)
President: Anne McCarthy
American Committee of Molecular, Cellular and
Immunoparasitology (ACMCIP)
President: Sarah Volkman
23
www.astmh.org
Affiliate Membership & Travel Awards
Affiliate (Organizational) Membership
ASTMH Affiliate Members
Affiliate membership is an opportunity for a company, corporation, foundation or other type of organization to support ASTMH and its mission.
Affiliate members designate one individual to serve as the main contact and
receive society mailings. Affiliate membership benefits include:
Patron
GlaxoSmithKline
• Recognition in ASTMH publications and at the annual meeting, and
• Discounts on annual meeting exhibit space fees, journal advertising rates
and list rentals
Donor
Techlab Inc.
Affiliate membership is available at the Patron, Donor and Contributor levels. Contact ASTMH headquarters for details or to request an application.
2007 Travel Awards
Supported with funding from the Bill
& Melinda Gates Foundation and the
National Institutes
of Health/National Institute of Allergy
and Infectious Diseases
Jane Achan
Makerere University
Kampala, Uganda
Abstract 705
Contributor
Merck Research Laboratories
Panbio Inc.
Francisco Diaz
Universidad de Antioquia
Medellin, Colombia
Abstract 446
Colince Kamden
University of Yaounde
Yaounde, Cameroon
Abstract 1035
Nancy Duah
London School of Hygiene and
Tropical Medicine
London, United Kingdom
Abstract 302
Marisa Madison
Meharry Medical College
Nashville, Tennessee USA
Abstract 648
Hugo Razuri
Uniformed Services University
of the Health Sciences
Bethesda, Maryland USA
Abstract 332
Vivornpun Sanprasert
Chulalongkorn University
Bangkok, Thailand
Abstract 784
Gretchen Ehrenkaufer
Stanford University
Stanford, California USA
Abstract 1048
Hortance Manda
International Centre of Insect
Physiology and Ecology (ICIPE)
Mbita Point, Kenya
Abstract 1026
Autumn Girouard
Johns Hopkins Bloomberg School of
Public Health
Baltimore, Maryland USA
Abstract 961
Frank Mannix
Tulane University School of Public
Health and Tropical Medicine
New Orleans, Louisiana USA
Abstract 130
Andrew Helmers
University of Toronto
Toronto, Ontario, Canada
Abstract 164
Flavia McBride
Universidade Federal da Bahia
Salvador, Brazil
Abstract 98
Win Surachetpong
University of California, Davis
Davis, California USA
Abstract 251
M. Paola Boggiatto
Iowa State University
Ames, Iowa USA
Abstract 142
Andres Herrera
United States Naval Medical
Research Center Detachment
Lima, Peru
Abstract 747
Charles McGee
University of Texas Medical Branch
Galveston, Texas USA
Abstract 658
2007 American
Committee of Medical
Entomology (ACME)
Travel Awards
Mouhamadou Seidou Chouaibou
Organisation de Coordination pour la
lutte contre les Endémies en Afrique
Centrale (OCEAC)
Yaounde, Cameroon
Abstract 865
Nusrat Homaira
International Centre for Diarrheal
Disease Research, Bangladesh
(ICDDR,B)
Dhaka, Bangladesh
Abstract 281
James Colborn
Centers for Disease Control and
Prevention
Fort Collins, Colorado USA
Abstract 913
Emily Jentes
Tulane University School of Public
Health and Tropical Medicine
New Orleans, Louisiana USA
Abstract 259
A. Paige Adams
University of Texas Medical Branch
Galveston, Texas USA
Abstract 278
Christopher Barker
University of California, Davis
Davis, California USA
Abstract 584
Ron Birnbaum
Harbor-UCLA Medical Center
Los Angeles, California USA
Abstract 631
Alexander Yaw Debrah
Kwame Nkrumah University of
Science and Technology
Kumasi, Ghana
Abstract 388
Arthur Mpimbaza
Makerere University
Kampala, Uganda
Abstract 352
Olusola Ojurongbe
Ladoke Akintola University of
Technology
Osun State, Nigeria
Abstract 523
John Ongecha
Kenya Medical Research Institute
Kisumu, Kenya
Abstract 694
Rachaneeporn Jenwithisuk
Armed Forces Research Institute of
Medical Sciences (AFRIMS)
Bangkok, Thailand
Abstract 515
24
Mariana Simoes
Fundacao Oswaldo Cruz
(FIOCRUZ)
Belo Horizonte, Brazil
Abstract 286
Peter Odada Sumba
Kenya Medical Research Institute
Kisumu, Kenya
Abstract 557
Maria Julia Dantur Juri
National University of Tucuman
Tucuman, Argentina
Abstract 398
Lisa Purcell
McGill University
Sainte-Anne-de-Bellevue, |
Quebec, Canada
Abstract 36
www.astmh.org
General Meeting Information
Continuing Medical Education
Pre-Meeting Course Registration Hours
Accreditation
The American Society of Tropical Medicine and Hygiene
is accredited by the Accreditation Council for Continuing
Medical Education (ACCME) to provide continuing medical
education for physicians.
Grand Ballroom Foyer
Friday, November 2
Continuing Medical Education Credits
Sunday, November 4
Monday, November 5
Tuesday, November 6
4 p.m. – 6 p.m.
7 a.m. – 1:30 p.m.
Annual Meeting Registration Hours
The American Society of Tropical Medicine and Hygiene
designates this educational activity for a maximum of
37.25 AMA PRA Category 1 Credit(s)™. Physicians should
claim only credit commensurate with the extent of their
participation in the activity.
10:30 a.m. - 6 p.m.
7 a.m. - 5 p.m.
7 a.m. – 5 p.m.
7 a.m. – 5 p.m.
7 a.m. – 10:30 a.m.
Messages and Emergency Calls
A message board will be available near the ASTMH registration desk. Check
the message board often to retrieve your messages. Phone calls should be
directed to 215/625-2900, the main switchboard of the Philadelphia
Marriott Downtown. Callers should ask to be connected to the ASTMH registration desk. Faxes can be sent to the hotel at 215/625-6000.
Register for CME Credit
The CME documentation fee is $100. CME certificates
will be mailed six-to-eight weeks after the annual meeting.
Complete your CME evaluation form online! Visit the
ASTMH Cyber Café and complete your online CME
Attendance and Evaluation Form while at the meeting.
Or use your own computer to access the evaluation form
at www.astmh.org/cme.
Badges/Access Control
Participation in the ASTMH Annual Meeting is limited to registered attendees. The official badge is required for admission to all sessions, social activities and the exhibit area. Do not place a business card into the badgeholder
as identification. If there is an error on a badge, please have it corrected at
the registration desk.
Full Disclosure Policy Affecting CME Activities
Consistent with ASTMH policy, faculty for this meeting
are expected to disclose any economic or other personal
interests that create, or may be perceived as creating, a
conflict related to the material discussed. All conflicts of
interest must be resolved prior to the annual meeting.
Replacement Badge
If your badge is lost, you must purchase a replacement badge for a fee of
$15. Bring your photo I.D. with you to the registration desk to have a new
badge issued. This fee will not be refunded if you find your original badge.
In addition, consistent with ASTMH policy, faculty are
expected to disclose to attendees at the beginning of
their presentation(s) any product mentioned during their
presentation that is not labeled for the use under discussion
or is still investigational. This policy is intended to allow
you to form your own judgments about such material.
Spouse/Guest Registration
(Only for those outside the tropical medicine field)
Spouse/guest registration includes admission to the opening reception on
Sunday, admission to the exhibit hall, plenary sessions and poster sessions only.
th
25
AnnualMeeting
ASTMH
General Information
www.astmh.org
Food Functions
Cyber Café
The following food functions are included in the registration fee:
• Opening reception (Sunday)
• Late Breakers in Clinical Tropical Medicine and Basic Science/Molecular
Biology light dinner (Monday)
• Poster session lunches (Monday, Tuesday and Wednesday)
• Coffee breaks
Visit the Cyber Café in the Franklin Hall Foyer on the fourth floor. As a
courtesy to other attendees, we ask that you limit your computer use to ten
minutes per visit.
Hotel Information
Monday, November 5
Tuesday, November 6
Press Room
The press room is located in Room 403 on the fourth level. ASTMH press
kits are available. Press announcements and other details can be found in
Room 403. Press room hours of operation are:
The Philadelphia Marriott Downtown will be the site of all annual meeting
activities.
1201 Market St.
Philadelphia, PA 19107
215/625-2900
Fax: 215/625-6000
7:30 a.m. – 6:30 p.m.
7:30 a.m. – 6:30 p.m.
8 a.m. – 6 p.m.
8 a.m. – 2 p.m.
Employment Opportunities
Bulletin boards for posting employment opportunities are available in the
ASTMH registration area.
Career Center
Americans with Disabilities Act
The ASTMH online Career Center, available at www.astmh.org, features a
fresh, user-friendly design and enhanced functionality. In addition to viewing
a wide range of available positions in the tropical medicine and hygiene
field, members can now post resumes anonymously and search for jobs by
keyword, location and job type. Employers can set up an account, post
open positions on the ASTMH Web site, buy classified ad space in the
American Journal of Tropical Medicine and Hygiene and search the ASTMH
resume bank for qualified applicants.
ASTMH fully complies with the legal requirements of the ADA and the rules
and regulations thereof.
Camera Restrictions/Recording Devices
Hotel Parking
Parking at the Philadelphia Marriott Downtown is currently $36 for
overnight valet parking with in/out privileges. If you choose to self-park, a
garage is located directly across the street from the hotel. The rate is $28
for 24 hours with no in/out privileges.
Only registered members of the press and attendees who receive approval
from ASTMH staff may take cameras into the exhibit hall or use recording
devices during sessions.
Exhibits
Exhibit Hall
The ASTMH 56th Annual Meeting features an exposition of displays by leading suppliers and vendors. A complete exhibitor and supporter directory is
included in the registration packet.
Disclaimer
ASTMH is not responsible for the opinions expressed by speakers or the
content of speaker handout materials.
Exhibit Hours
Sunday, November 4
Monday, November 5
Tuesday, November 6
Meeting Evaluation
7:30 p.m. – 9:30 p.m.
9:30 a.m. – 10:30 a.m.
Noon – 1:30 p.m.
3 p.m. – 4 p.m.
9:30 a.m. – 10:30 a.m.
Noon – 3 p.m.
9:30 a.m. – 10:30 a.m.
Noon – 2:30 p.m.
ASTMH needs your input to enhance future meetings. An online meeting
evaluation survey will be e-mailed to you shortly after the meeting. Your
participation in this survey is greatly appreciated.
The scientific program committee welcomes your input concerning the format and planning of this and future ASTMH meetings. Organization of symposia and participation in educational program planning through the program committee is encouraged for all interested ASTMH members.
Solicitations
Sales and promotional activities are restricted to exhibitors and must take
place in their assigned exhibit area. Solicitations by unauthorized persons
are strictly prohibited.
26
www.astmh.org
Program Information
The American Journal of Tropical
Medicine & Hygiene
New this year!
Annual Meeting Audio Recordings
Trial Journal Subscriptions
Can’t figure out how to be in two places at once?
Problem solved! With so much cutting-edge science available
at the ASTMH conference, you will now be able to purchase
audio recordings of sessions you missed.
The American Journal of Tropical Medicine and Hygiene has
included a complimentary trial subscription number in your
registration packet. Non-members can activate this 90-day trial
to enjoy the benefits of an online journal subscription at no charge.
Members already enjoy a subscription to the online journal and can
pass the trial subscription number along to a non-member colleague.
Visit the sales desk in the registration area to purchase a
CD and/or multimedia CD-ROM of the conference sessions
from IntelliQuest Media. Discounts will be extended for onsite
orders. You may contact them at 866-651-2586 or visit
www.intelliquestmedia.com.
ASTMH Journal Symposium
Preparation and Review of Scientific
Manuscripts for the American Journal
of Tropical Medicine & Hygiene
Late Breaker Abstracts
Mid-Day Session 32
Monday, November 5
12:15 pm - 1:15 pm
Franklin 2
Late Breakers in Basic Science/Molecular Biology
Monday, November 5
7 p.m. – 9 p.m.
Salon CD
This session is designed to educate attendees about the Journal
and the publishing process as a whole. Discussion will focus on
how manuscripts are reviewed, edited and processed by the Journal,
and will include pointers on preparation and review of manuscripts.
See the handout in your registration packet for more information.
We encourage you to ask questions at this session and would like
to hear your feedback on the Journal.
Monday, November 5
7 p.m. – 9 p.m.
Salon AB
These sessions are designed for brief presentations of important, new data
obtained after the closing date for abstract submission. Oral late breaker
presentations will take place on Monday evening. Poster late breaker presentations will take place during the poster sessions on Monday, Tuesday
and Wednesday. A schedule of late breaker abstract presentations can be
found in your registration packet.
Meet the Professors
Meet the Professors sessions are small, interactive programs held on
Monday, Tuesday and Wednesday. Special student sessions will be held on
Monday at 7 a.m. and Tuesday evening at 7:15 p.m. The sessions are open
to all meeting participants and a light meal will be provided. While the professors will lead the program and have some prepared remarks, the sessions
will be largely question-and-answer format.
ACMCIP Abstracts
Throughout this book, you will notice that some abstracts are followed by
the notation “(ACMCIP abstract).” This notation means the abstract submitter indicated that the abstract pertains to molecular, cellular or immunoparasitology. ACMCIP refers to the American Committee of Molecular, Cellular
and Immunoparasitology, an ASTMH subgroup. For more information, go to
http://www.astmh.org/sic/acmcip.cfm.
27
www.astmh.org
Special Events for Trainees (Students,
Fellows, Residents and Junior Faculty)
Salon CD
Mid-Day Session 130: PubMed and HINARI: Searching and Getting
the Articles You Want (page 185)
12:15 p.m. - 1:15 p.m.
Salon F
Events featuring light meals denoted with an asterisk.
Sunday, November 4
11 a.m. – 3:30 p.m.
Independence I, II, and III, Liberty A and C
Mid-Day Session 132: National Institutes of Health Grants:
Grantsmanship, Review and Funding Opportunities
(page 185)
12:15 p.m. - 1:15 p.m.
Salon KL
Student Reception*
Sunday, November 4
4 p.m. – 5 p.m.
Porthole Room (follow signs across the bridge on third floor)
Other Sessions for Career Development
The ASTMH council invites students, postdoctoral fellows and residents to
the student reception. This reception is an opportunity to meet fellow
trainees and interact with society leaders.
Parasitology Pre-Meeting Course:
Systems Biology: Approaches to Understanding Infectious Disease
8:30 a.m. - 4:45 p.m.
Salon F
Session 1: Meet the Professors A (page 46)*
Fireside Chat: Personal Experiences, Words of Wisdom and
Institutional Perspectives
Monday, November 5
7 a.m. – 8 a.m.
Salon G
Light breakfast provided
Clinical Pre-Meeting Course:
Chagas Disease (American Trypanosomiasis): No Longer an Exotic
Disease (page 34)
Saturday, November 3, Noon - 5 p.m.
Sunday, November 4, 7:30 a.m. - 3 p.m.
Salon E
Mid-Day Session 29: Career Pathways in Global Health (page 84)*
Monday, November 5
12:15 p.m. - 1:15 p.m.
Salon H
Light lunch provided
Plenary Session I and Society Awards Ceremony (page 45)
Sunday, November 4
5:30 p.m. - 7:30 p.m.
Salon GH
Symposium 68: Global Health Symposium on Tropical Medicine
(page 106)
Supported with funding from the Bill and Melinda Gates Foundation
Tuesday, November 6
10:15 a.m. - Noon
Salon CD
Opening Reception
Sunday, November 4
7:30 p.m - 9:30 p.m
Franklin Hall
Symposium 5: American Committee of Molecular, Cellular and
Immunoparasitology (ACMCIP): Genomic Approaches to Host and
Parasite Interactions (page 47)
Monday, November 5
8 a.m. - 9:45 a.m.
Salon F
Mid-Day Session 78: Bioinformatics Resources for Tropical Diseases:
NCBI Resource Update (page 134)
Tuesday, November 6
12:15 p.m. - 1:15 p.m.
Salon AB
Symposium 10: Tropical Medicine and the Media (page 49)
Monday, November 5
8 a.m. - 9:45 a.m.
Liberty AB
Mid-Day Session 79: ASTMH Trainee Lunch with Education
Committee (page 134)*
Tuesday, November 6
12:15 p.m. - 1:15 p.m.
Salon CD
Light lunch provided
Mid-Day Session 32: Preparation and Review of Scientific
Manuscripts for the American Journal of Tropical Medicine & Hygiene
(page 84)
Monday, November 5
12:15 p.m. - 1:15 p.m.
Franklin 2
Evening Session 103: Meet the Professors D (page 147)*
American Committee of Molecular, Cellular and Immunoparasitology
(ACMCIP): Professional Development Series on Mentoring
Tuesday, November 6
7:15 p.m. - 9 p.m.
Salon H
Light dinner provided
Symposium 36: American Committee of Medical Entomology
(ACME) I: Andrew Spielman’s Contributions to Medical Entomology
(page 87)
Monday, November 5
1:30 p.m. - 3:15 p.m.
Salon F
Symposium 118:
Launching Careers In Tropical Disease Research:
Progress Reports From The Burroughs Wellcome Fund/ASTMH and
Fogarty International Center IRDSA Fellows (page 157)
10:15 a.m. - Noon
28
Symposium 46: American Committee of Medical Entolomogy
(ACME) II: Andrew Spielman’s Contributions to Medical Entomology
(page 93)
Monday, November 5
3:45 p.m. - 5:30 p.m.
Salon F
Scientific Session 161: American Committee of Molecular, Cellular
and Immunoparasitology (ACMCIP): Molecular Parasitology I
(page 204)
8 a.m. - 9:45 a.m.
Salon G
Featuring invited talks from Woods Hole parasitology meeting award-winning presenters.
Symposium Session 70: American Committee on Arthropod-Borne
Viruses (ACAV): Modulation of Innate Immune Responses in
Vertebrate and Arthropod Host Cells By Arboviruses (page 108)
Tuesday, November 6
10:15 a.m. - 12:45 p.m.
Salon F
and Immunoparasitology (ACMCIP): Molecular Parasitology II
(page 209)
10:15 a.m. - Noon
Salon G
Symposium 85: Clinical Group I (page 137)
Tuesday, November 6
2:45 p.m. - 4:30 p.m.
Salon E
Scientific Session 86: American Committee of Molecular, Cellular and
Immunoparasitology (ACMCIP): Cellular Parasitology I (page 138)
Tuesday, November 6
2:45 p.m. - 4:30 p.m.
Salon F
Featuring invited talks from Woods Hole parasitology meeting award-winning
presenters.
Elsevier Student Book Award Applicants
Symposium 95: Clinical Group II (page 142)
Tuesday, November 6
5 p.m. - 6:45 p.m.
Salon E
Please support these young scientists by attending
their presentations throughout the conference.
This award recognizes excellence in clinically-oriented research presented by students (within six months of completing undergraduate or
master’s level training, including medical undergraduate degrees) or
those in graduate medical training, of work submitted and presented
(oral or poster) at the ASTMH Annual Meeting.
Abstract 187
High prevalence of asymptomatic malaria infections in the
Papua New Guinea Defence Force
Edwin Siu
Scientific Session 96: American Committee of Molecular, Cellular and
Immunoparasitology (ACMCIP): Cellular Parasitology II (page 143)
Tuesday, November 6
5 p.m. - 6:45 p.m.
Salon F
presenters.
Abstract 654
Antimalarial activity and mechanism of action of artemisinin
antimalarials: Is the digestive vacuole (DV) the primary target?
Maria del Pilar Crespo Ortiz
and Immunoparasitology (ACMCIP): Immunoparasitology I (page 151)
8 a.m. - 9:45 a.m.
Salon G
presenters.
Abstract 733
Assessment of clinical tropical medicine competency among
U.S.-trained medical students and residents
Lipi Roy
Abstract 747
The effect of preparation of Cebiche on the survival of Escherichia
coli, Aeromonas hydrophila and Vibrio parahemolyticus
Andres Herrera
Scientific Session Session 121: American Committee of Molecular,
Cellular and Immunoparasitology (ACMCIP): Immunoparasitology II
(page 158)
10:15 a.m. - Noon
Salon G
Abstract 752
Glutamine and zinc support brain development in suckling Swiss
mice challenged by undernutrition
Ibraim Cavalcante de Castro
Abstract 793
Acute Chagas disease outbreak associated to Açaí Juice
Consumption — Pará State/Brazil, 2006
Aglaer Alves da Nobrega
Mid-Day Session 132A: Workers in Tropical Medicine Video: Karl M.
Johnson, MD: Life and Legend of a Leader in Tropical Virology (page
186)
12:15 p.m. - 1:15 p.m.
Franklin 1
Abstract 1027
A means to an end: Comparative analysis of chromosomal
inversions frequency and distribution in the major malaria
vectors Anopheles gambiae and Anopheles funestus across
ecologically diverse environments in Cameroon
Diego Ayala
Plenary Session IV: Presidential Address and Annual Business Meeting
6 p.m. - 7:30 p.m.
Salon GH
29
www.astmh.org
Detailed Program
Poster Sessions
Online Program Options
Following the meeting, search the annual meeting program online by
abstract word, title, subject, author and presentation time at
http://www.astmh.org.
Franklin Hall B
Poster Session Schedule
Poster Session A
Setup:
Monday, November 5
9:45 a.m. – 10:15 a.m.
Viewing:
Monday, November 5
10:15 a.m. – Noon
1:30 p.m. – 7 p.m.
Late breaker abstracts and post-publication changes in the program and
abstracts can be found on the ASTMH Web site.
Presentations:
Monday, November 5
Noon – 1:30 p.m.
Speaker Ready Room and Audiovisual Facilities
Rooms 413 and 415
Dismantle:
Monday, November 5
7 p.m. – 8 p.m.
Audio-visual preview and submission facilities are provided beginning
Saturday, November 4 at noon in rooms 414 and 415 on the fourth floor.
All oral presentations must use PowerPoint.
Poster Session B
Setup:
Tuesday, November 6
9:45 a.m. – 10:15 a.m.
Viewing:
Tuesday, November 6
10:15 a.m. – Noon
1:30 p.m. – 7 p.m.
Pre-load your presentation in the Speaker Ready Room 24 hours prior to
your session. If you are unable to do so, and you have a morning presentation, please go directly to the meeting room to load your presentation at
least one half-hour before your session. If you have an afternoon presentation and are unable to load your presentation the day before, visit the
Speaker Ready Room on the morning of your talk.
Presentations:
Tuesday, November 6
Noon – 1:30 p.m.
Dismantle:
Tuesday, November 6
7 p.m. – 8 p.m.
Your presentation should be saved on a floppy disk, CD-R or memory stick.
The CD-R should be in a version that can be read on any PC CD-ROM. If
you use a Mac, make sure that your presentation is readable via PC
PowerPoint.
Poster Session C
Setup:
9:45 a.m. – 10:15 a.m.
Presentations:
Noon – 1:30 p.m.
Viewing:
10:15 a.m. – Noon
1:30 p.m. – 7 p.m.
Dismantle:
7 p.m. – 8 p.m.
If your presentation includes a video segment, it is very important that you
visit the Speaker Ready Room and advise the AV techs of the video.
A computer and LCD projector will be set up in each presentation room.
You cannot present your talk from your own laptop. Your presentation will
be run from the AV technician’s PC-based computer.
We strongly encourage you to pre-load your presentation in the Speaker
Ready Room 24 hours prior to presentation time.
Three poster sessions will be held at the ASTMH 56th Annual Meeting in
Franklin Hall B on the fourth floor. There are additional times for poster
viewing (presenters need not be in attendance during these time periods).
Speaker Ready Room Hours
Sunday, November 4
Monday, November 5
Tuesday, November 6
We encourage attendees to visit the poster hall throughout the day. Poster
viewing time is scheduled each day in the morning and afternoon.
30
Noon – 5 p.m.
7 a.m. – 6 p.m.
7 a.m. – 6 p.m.
7 a.m. – 6 p.m.
7 a.m. – 6 p.m.
7 a.m. – Noon
MARK YOUR CALENDAR!
ASTMH 57th
Annual Meeting
December 7-11, 2008
Sheraton New Orleans
New Orleans, Louisiana
ASTMH 58th
Annual Meeting
November 18-22, 2009
Marriott Wardman Park
Washington, DC
www.astmh.org
New Orleans, LA
Washington, DC
60 Revere Drive
Suite 500
Northbrook, IL 60062 USA
Phone: 847/480-9592
Fax: 847/480-9282
info@astmh.org
http://www.astmh.org
31
www.astmh.org
Calista and Ottis Causey
Workers in Tropical Medicine
Video Presentation
Franklin Hall Foyer
Workers in Tropical Medicine:
Oral History Project Re-Initiated
Thomas H. Weller
Selected biographical videos of ASTMH members
who have made important contributions to
the field of tropical medicine will be shown
at the annual meeting. A viewing station in the
Franklin Hall Foyer has been reserved where
interested visitors can view DVDs of their choice.
DVD histories available include:
• Jordi Casals
Robert Coatney
• K.F. Meyer
• William Reeves
• Albert Sabin
• Thomas Weller
• Telford Work
And others……
Alexander Langmuir
Telford H. Work
32
William C. Reeves
In addition, the Society has begun to produce new
video biographies, with the intent of publishing
these pieces in the ASTMH journal with links to
the video/audio versions on the Web.
Jordi Casals-Ariet
The first video of the new series is “Karl M.
Johnson, MD: Life and Legend of a Leader in
Tropical Virology,” to be screened at the
conference on Wednesday, November 7 from
12:15 p.m. – 1:15 p.m. This project has obvious
importance to the field of tropical medicine and
the Society. We urge you to visit the viewing area
and value your comments and suggestions.
th
AnnualMeeting
ASTMH
Thomas P. Monath
Karl F. Meyer
Albert Sabin
33
www.astmh.org
www.astmh.org
Detailed Program
Friday, November 2
1:30 p.m.
APIDB: A SYSTEMS BIOLOGY DATABASE OF
APICOMPLEXAN PARASITES
David Roos
University of Pennsylvania, Philadelphia, PA, United States
Friday, November 2, 2007 4 p.m. - 6 p.m.
2:15 p.m.
SYSTEMS BIOLOGY IN MALARIA
Elizabeth A. Winzeler
The Scripps Research Institute, La Jolla, CA, United States
3 p.m.
PROTEIN-PROTEIN INTERACTIONS: ROLE IN
SYSTEMS BIOLOGY
Saturday, November 3, 2007 7 a.m. - 1:30 p.m.
Robert E. Hughes
Parasitology Pre-Meeting Course:
Buck Institute for Age Research, Novato, CA, United States
Systems Biology: Approaches to Understanding
Infectious Disease
3:45 p.m.
PANEL DISCUSSION
Salon F
Saturday, November 3, 2007 8:30 a.m. - 4:45 p.m.
Chagas Disease (American Trypanosomiasis):
No Longer an Exotic Disease
This course targets scientists, physicians, clinicians, graduate students and
educators with interests in the rapidly evolving field of systems biology and
its use in understanding the complex interactions and pathways involved in
infectious diseases. Topics include an overview of systems biology, database
development and visualization tools, uncovering complex protein interactions, identifying large scale networks of interactions and how these efforts
are being used to understand complex human biology and response to
pathogens.
Salon E
Saturday, November 3, 2007 Noon - 5 p.m.
Recent implementation of donor screening for Trypanosoma cruzi infection
by the American Red Cross and other blood banks across the United States
highlights the urgent need for clinicians, laboratorians and public health
professionals to understand Chagas disease, its diagnosis and treatment. In
the United States, it is estimated that more than 100,000 immigrants have
Chagas disease and most are unaware of their infection. This intensive
course provides a comprehensive review of the disease for tropical disease
experts, cardiologists, obstetricians, blood bankers and others. It covers the
epidemiology of infection in Latin America, where 10-12 million persons are
infected, and the situation outside of Latin America, such as in the United
States, where in addition to infected immigrants, cases of Chagas disease
have been transmitted by local vectors, by blood transfusion, by organ
transplantation, congenitally and by laboratory accident.
8:30 a.m.
COFFEE AND LIGHT CONTINENTAL BREAKFAST
9 a.m.
INTRODUCTION - COURSE GOALS AND OUTLINE
Daniel J. Carucci
Foundation for National Institutes of Health, Bethesda, MD, United States
Robert E.W. Hancock
University of British Columbia, Vancouver, BC, Canada
The course focuses on the diagnosis and management of acute, chronic and
congenital infections; cardiac and gastrointestinal complications; and considerations for special populations such as immunocompromised persons or
pregnant mothers. In addition, there will be updates on the status of control
programs in endemic countries, implementation of blood donor screening in
the Unites States, scientific developments in diagnosis and treatment and
the experience of the Centers for Disease Control and Prevention Drug
Service, which is the sole source of anti-parasitic drug for Chagas disease in
the United States. A series of case histories will illustrate the approach to
the person with subclinical infection and other syndromes.
Alan Aderem
Institute for Systems Biology, Seattle, WA, United States
9:15 a.m.
INTRODUCTION TO SYSTEMS BIOLOGY
Alan Aderem
Institute for Systems Biology, Seattle, WA, United States
10 a.m.
COMPUTATIONAL SYSTEMS AND VISUALIZATION TOOLS
Robert E.W. Hancock
Noon
INTRODUCTION AND OVERVIEW
10:45 a.m.
James Maguire
University of Maryland, Baltimore, MD, United States
BREAK
Susan Montgomery
Noon
Centers for Disease Control and Prevention Atlanta, GA, United States
Lunch (on your own)
34
www.astmh.org
Sunday, November 4
Parasite, Epidemiology and Control
12:15 p.m.
Speaker Ready Room
HISTORY OF CHAGAS DISEASE IN THE AMERICAS
James Maguire
Rooms 413-415
Sunday, November 4, 2007 7 a.m. - 6 p.m.
12:30 p.m.
TRYPANOSOMA CRUZI, TRANSMISSION AND PATHOGENESIS
Rick L. Tarleton
Chagas Disease (American Trypanosomiasis): No Longer
an Exotic Disease
University of Georgia, Athens, GA, United States
1 p.m.
Salon E
EPIDEMIOLOGY AND CONTROL
Sunday, November 4, 2007 7:30 a.m. - 3 p.m.
Caryn Bern
7:30 a.m.
Centers for Disease Control and Prevention, Atlanta, GA, United States
COFFEE AND LIGHT CONTINENTAL BREAKFAST
Ellen Dotson
Diagnosis and Parasitological Treatment
Clinical Aspects and Management
8 a.m.
1:45 p.m.
DIAGNOSIS
Louis Vaughn Kirchhoff
BREAK
University of Iowa, Iowa City, IA, United States
2:15 p.m.
ACUTE, CONGENITAL AND REACTIVATED INFECTIONS
9 a.m.
Sergio Sosa-Estani
PARASITOLOGICAL TREATMENT
Sergio Sosa-Estani
Centro Nacional de Diagnóstico e Investigación de Endemo-epidemias
(CeNDIE), ANLIS Dr. Carlos G. Malbrán, Buenos Aires, Argentina
Centro Nacional de Diagnóstico e Investigación de Endemo-epidemias
(CeNDIE), ANLIS Dr. Carlos G. Malbrán, Buenos Aires, Argentina
3 p.m.
CHRONIC INFECTIONS: INDETERMINATE
10 a.m.
Anis Rassi, Jr.
BREAK
Anis Rassi Hospital, Goiania, Brazil
Chagas in the United States
3:30 p.m.
10:30 a.m.
CHRONIC INFECTIONS: CARDIAC
CHAGAS DISEASE AND THE BLOOD SUPPLY
Anis Rassi, Jr.
Susan Stramer
Anis Rassi Hospital, Goiania, Brazil
American Red Cross, Gaithersburg, MD, United States
4:15 p.m.
David Leiby
CHRONIC INFECTIONS: GASTROINTESTINAL
American Red Cross, Rockville, MD, United States
James Maguire
11:15 a.m.
CENTERS FOR DISEASE CONTROL AND PREVENTION
EXPERIENCES AND CHALLENGES FOR THE U.S.
4:45 p.m.
Susan Montgomery
PANEL DISCUSSION
11:45 a.m.
Speaker Ready Room
PANEL DISCUSSION
Rooms 413-415
Noon
Saturday, November 3, 2007 Noon - 5 p.m.
LUNCH (ON YOUR OWN)
35
Sunday, November 4
www.astmh.org
Detailed Program
1:30 p.m.
11 a.m.
684
DIAGNOSIS, TREATMENT AND PREVENTION - SCIENTIFIC
DEVELOPMENTS
BURDEN AND EPIDEMIOLOGY OF INFLUENZA-LIKE ILLNESS IN
A PEDIATRIC COHORT IN NICARAGUA
Rick L. Tarleton
Aubree Gordon1, Guillermina Kuan2, Oscar Ortega3, Miguel
Reyes2, Saira Saborio4, Angel Balmaseda5, Eva Harris6
2:15 p.m.
1
Division of Epidemiology, School of Public Health, University of California,
Berkeley, Berkeley, CA, United States, 2Socrates Flores Vivas Health Center,
Managua, Nicaragua, 3Sustainable Sciences Institute, Managua, Nicaragua,
4
Department of Virology, Centro Nacional de Diagnóstico y Referencia,
Ministry of Health, Managua, Nicaragua, 5Departamento de Virologia,
Centro Nacional de Diagnostico y Referencia, Ministerio de Salud, Managua,
Nicaragua, 6Division of Infectious Diseases, School of Public Health,
University of California, Berkeley, Berkeley, CA, United States
Press Room
11:15 a.m.
CASE PRESENTATIONS AND DISCUSSION
Rooms 305-306
428
Room 403
EOSINOPHILIA AS A DIAGNOSTIC TOOL FOR
ANGIOSTRONGYLIASIS
Registration
Kittisak Sawanyawisuth1, Somsak Tiamkao2, Pewpan M.
Intapan2, Panita Limpawattana2, Wichai Senthong2, Suthipun
Jitpimolmard2, Verajit Chotmongkol2, Elizabeth B. Connor1
1
University of California, San Diego, La Jolla, CA, United States,
Khon Kaen University, Khon Kaen, Thailand
2
Cyber Cafe
11:30 a.m.
Franklin Hall Foyer
457
DENGUE VIRUS CROSS-REACTIVE MOUSE OR HUMANIZED
CHIMPANZEE MONOCLONAL ANTIBODIES FAVOR ENHANCED
DENGUE VIRUS IMMUNE COMPLEX INFECTIVITY IN
ENGINEERED HUMAN FC GAMMA RECEPTOR CD64 OR CD32EXPRESSING CELLS
In Honor of William A. Petri, Sr.
In Memory of Annie Liberati
Supported with funding from TechLab Inc.
W. W. Shanaka I. Rodrigo1, Ana P. Goncalvez2, Xia Jin1, Robert C.
Rose1, Ching-Juh Lai2, Jacob J. Schlesinger1
ASTMH will present the Young Investigator Award to outstanding young
researchers during the 56th Annual Meeting. This award encourages developing young scientists to pursue careers in various aspects of tropical disease research.
1
University of Rochester School of Medicine and Dentistry, Rochester, NY,
United States, 2National Institutes of Health, Bethesda, MD, United States
11:45 a.m.
359
Young Investigator Award Session A
A RAPID HEALTH IMPACT ASSESSMENT OF THE AFRICAN
PROGRAMME FOR ONCHOCERCIASIS CONTROL (APOC)
Independence I
Sunday, November 4, 2007 11 a.m. - 3:30 p.m.
Wilma A. Stolk, Lennert J. Veerman, Sake J. de Vlas, J. Dik Habbema
Department of Public Health, Erasmus MC, Rotterdam,
The Netherlands
JUDGES
Subash Babu
National Institutes of Health/National Institute of Allergy and Infectious
Diseases, Bethesda, MD, United States
Noon
948
Stephen Davies
Uniformed Services University of the Health Sciences, Bethesda, MD,
United States
Daniel J. Tisch
TWO WEEKS OF REPEATED PARASITE EXPOSURES DO NOT
INCREASE THE SUSCEPTIBILITY OF VACCINATED MICE TO
HELMINTH INFECTIONS
Case Western Reserve University, Cleveland, OH, United States
Marc P. Hübner, Marina N. Torrero, Edward Mitre
United States
36
2 p.m.
289
149
TRANSGENESIS OF SCHISTOSOMA MANSONI MEDIATED BY
MURINE LEUKEMIA VIRUS
THE ROLE OF ACRIFLAVIN IN THE PROLIFERATION OR INHIBITION OF TRYPANOSOMA MUSCULI BY INDUCING APOPTOSIS
WITH SPECIFIC BINDING AFFINITY TO KDNA OF THE PARASITE
IN VITRO AND IN VIVO
Kristine J. Kines1, Maria E. Morales1, Victoria H. Mann1,
Geoffrey N. Gobert2, Paul J. Brindley1
1
Tulane University, New Orleans, LA, United States, 2Queensland Institute of
Medical Research, Brisbane, Australia
Dereje D. Gimite, Mohammad Ashraf, Clarence M. Lee
Howard University, Washington, DC, United States
12:30 p.m.
2:15 p.m.
336
624
MOLECULAR AND EVOLUTIONARY EPIDEMIOLOGY OF
SCHISTOSOMA MANSONI IN HUMAN HOSTS
A PARATRANSGENIC APPROACH TO CONTROL OF VISCERAL
LEISHMANIASIS: AEROBIC GUT BACTERIAL IDENTIFICATION
FROM PHLEOTOMUS ARGENTIPUS
Michelle L. Steinauer1, Ian J. Wilson2, Gerald M. Mkoji3,
Eric L. Agola3, Ibrahim Ndugu3, Geoffrey Maina3, Diana Karanja4,
Eric S. Loker1
Amber L. Read1, Ravi Durvasula1, Ivy Hurwitz1, Bobban Subhadra1,
Mathews Scott1, Kashinath Ghosh2, Robin McKelvey1, Heidi
Hillesland1, Pradeep Das3
1
University of New Mexico, Albuquerque, NM, United States, 2University of
Newcastle upon Tyne, Newcastle upon Tyne, United Kingdom, 3Kenya
Medical Research Institute, Nairobi, Kenya, 4Kenya Medical Research
Institute, Kisumu, Kenya
1
University of New Mexico, Albuquerque, NM, United States, 2Walter Reed
Army Research Institute, Washington, DC, United States, 3Rajendra
Memorial Research Institute of Medical Sciences, Patna, India
12:45 p.m.
2:30 p.m.
786
175
IDENTIFYING TRYPANOSOMA CRUZI INFECTION IN CHILDREN
DURING A VECTOR CONTROL CAMPAIGN
MALARIA CONTROL IN THE MUNICIPALITY OF SAN ESTEBAN,
HONDURAS, CENTRAL AMERICA
Michael Z. Levy1, Vivian Kawai2, Natalie M. Bowman2, Lance A.
Waller1, Lilia Cabrera2, Viviana V. Pinedo-Cancino2, Amy E. Seitz1,
Frank J. Steurer3, Juan G. Cornejo del Carpio4, Eleazar CordovaBenzaquen5, James H. Maguire6, Robert H. Gilman7, Caryn Bern3
Christine E. Bell1, Stanley O. Foster1, Laurence Slutsker2, Raymond
Beach2, German Jimenez3, Maria Sarmiento4
1
Rollins School of Public Health, Emory University, Atlanta, GA, United
States, 2Centers for Disease Control and Prevention/CCID/NCZVED, Atlanta,
GA, United States, 3Honduras Outreach Inc., San Esteban, Honduras,
4
Municipal Health Promoter, San Esteban, Honduras
1
Emory University, Atlanta, GA, United States, 2AB Prisma, Lima, Peru,
Division of Parasitic Diseases, Centers for Disease Control and Prevention,
Atlanta, GA, United States, 4Dirección Regional del Ministerio de Salud,
Arequipa, Peru, 5AB Prisma, Arequipa, Peru, 6University of Maryland,
Baltimore, MD, United States, 7Bloomberg School of Public Health, Johns
Hopkins University, Baltimore, MD, United States
3
2:45 p.m.
697
RISK FACTORS FOR MALARIA IN A RURAL AMAZONIAN
COHORT (GRANADA, ACRE, BRAZIL)
1 p.m.
BREAK
Mônica da Silva-Nunes1, Natália T. Komatsu1, Camlia Juncansen1,
Rosane R. DÁrcádia1, Erika H. Hoffmann1, Estéfano A. Souza1,
Natal S. Silva1, Melissa S. Bastos2, Sandra L. Moraes-Ávila2,
Rosely S. Malafronte2, Kézia K. Scopel3, Érika M. Braga3,
Carlos E. Cavasini4, Pascoal T. Muniz5, Irene S. Soares1,
Marcelo U. Ferreira1
1:30 p.m.
999
THE ROLE OF SOCIAL EXCLUSION AND DEFORESTATION IN
THE SPATIO-TEMPORAL PATTERNS OF CUTANEOUS
LEISHMANIASIS IN COSTA RICA
1
Universidade de São Paulo, São Paulo - SP, Brazil, 2Instituto de Medicina
Tropical, São Paulo - SP, Brazil, 3Universidade Federal de Minas Gerais, Belo
Horizonte - MG, Brazil, 4Faculdade de Medicina de São José do Rio Preto,
São José do Rio Preto - SP, Brazil, 5Universidade Federal do Acre, Rio Branco
- AC, Brazil
Luis F. Chaves, Justin M. Cohen, Mercedes Pascual, Mark L. Wilson
University of Michigan, Ann Arbor, MI, United States
1:45 p.m.
3 p.m.
792
596
IMMUNO-EPIDEMIOLOGY OF VISCERAL LEISHMANIASIS IN A
COHORT OF BRAZILIAN DOGS
STUDIES ON INSECTICIDE USAGE PATTERN AND RESISTANCE
STATUS OF ANOPHELES GAMBIAE S.S IN THE ASHANTI
REGION OF GHANA
Seyi Soremekun1, Rupert Quinnell2, Lourdes Garcez3, Paul Bates4,
Matthew Rogers5, Orin Courtenay1
Joseph B. Stiles-Ocran1, Michael D. Wilson1, Margaret T.
Frempong2, Williams K. Owiredu2, Daniel A. Boakye1
1
University of Warwick, Coventry, United Kingdom, 2University of Leeds,
Leeds, United Kingdom, 3Instituto Evandro Chagas, Belem, Brazil, 4Liverpool
School of Tropical Medicine, Liverpool, United Kingdom, 5London School of
Hygiene and Tropical Medicine, London, United Kingdom
1
Noguchi Memorial Institute for Medical Research, Legon, Accra, Ghana,
Kwame Nkrumah University of Science and Technology, Kumasi, Ghana
2
37
Sunday, November 4
12:15 p.m.
www.astmh.org
Detailed Program
www.astmh.org
3:15 p.m.
11:45 a.m.
890
468
DETECTING WUCHERERIA BANCROFTI IN AEDES POLYNESIENSIS MOSQUITOES FROM AMERICAN SAMOA: A COMPARISON
OF PCR WITH HAEMALUM STAINING AND DISSECTION
INTRACELLULAR LOCALIZATION, MEMBRANE ASSOCIATION
AND PROCESSING OF WNV NY99 STRAIN NS4B
Eric W. Chambers1, Melissa F. Avery1, Mark A. Schmaedick2,
Patrick J. Lammie1, Thomas R. Burkot1
University of Hawaii, Honolulu, HI, United States
1
Noon
Pakieli H. Kaufusi, Richard Yanagihara, Vivek R. Nerurkar
Atlanta, GA, United States, 2Division of Community and Natural Resources,
American Samoa Community College, Pago Pago, American Samoa
691
PATHOGENESIS OF CHIKUNGUNYA VIRUS INFECTION IN MICE
Young Investigator Award Session B
Sarah A. Ziegler, Liang Lu, Shu-Yuan Xiao, Robert B. Tesh
University of Texas Medical Branch, Galveston, TX, United States
Independence II
12:15 p.m.
612
JUDGES
Kathryn S. Aultman
CRIMEAN-CONGO HEMORRHAGIC FEVER VIRUS ENCODES AN
NSM PROTEIN
Bill & Melinda Gates Foundation, Seattle, WA, United States
Brenda T. Beerntsen
Louis A. Altamura1, Jose Stubbs1, Connie S. Schmaljohn2, Robert
W. Doms1
University of Missouri-Columbia, Columbia, MO, United States
1University of Pennsylvania, Philadelphia, PA, United States, 2United States
Army Medical Research Institute for Infectious Diseases, Fort Detrick,
Frederick, MD, United States
Nicholas Komar
Centers for Disease Control and Prevention, Fort Collins, CO, United States
11 a.m.
12:30 p.m.
105
927
STUDY ON THE CORRELATIONS AMONG OF CLIMATE FACTORS, MOSQUITO INDICES AND EPIDEMICS OF DENGUE IN
KAOHSIUNG, TAIWAN
THE MINIMAL DOMAIN OF THE EASTERN EQUINE ENCEPHALITIS VIRUS CAPSID NECESSARY FOR INHIBITION OF HOST GENE
EXPRESSION IS REQUIRED FOR VIRAL PATHOGENESIS
Chuin-Shee Shang1, Chung-Ming Liu2, Yi-Shiuan Li1, ChwanChuen King1
Patricia V. Aguilar1, Lawrence W. Leung1, Eryu Wang2, Scott C.
Weaver2, Christopher F. Basler1
1
Institute of Epidemiology, College of Public Health, National Taiwan
University, Taipei City, Taiwan, 2Global Change Researching Center, National
Taiwan University, Taipei City, Taiwan
1
Mount Sinai School of Medicine, New York, NY, United States, 2University
of Texas Medical Branch, Galveston, TX, United States
12:45 p.m.
11:15 a.m.
108
990
LONG-TERM CLIMATE AND ENDEMIC DENGUE TRANSMISSION
Michael Johansson , Greg Glass
EXAMINATION OF RIFT VALLEY FEVER VIRUS ENTRY DETERMINANTS USING SIRNA
1
Claire Marie Filone, Robert W. Doms, Sara Cherry
2
1
2
Centers for Disease Control and Prevention, San Juan, PR, United States,
Johns Hopkins School of Public Health, Baltimore, MD, United States
11:30 a.m.
1 p.m.
686
BREAK
DEFINITION OF THE MAJOR DETERMINANT RESPONSIBLE FOR
NEUROVIULENCE OF JAPANESE ENCEPHALITIS VIRUS
1:30 p.m.
942
Yoko Nukui, Shigeru Tajima, Chang Kweng Lim, Reiko Nerome,
Tomohiko Takasaki, Ichiro Kurane
LOCALIZATION OF NOVEL -CARBONIC ANYDRASES FROM THE
LARVAE OF ANOPHELES GAMBIAE AND AEDES AEGYPTI
Department of Virology I, National Institute of Infectious Diseases,
Tokyo, Japan
Kristin E. Smith, Leslie A. VanEkeris, Paul J. Linser
University of Florida, Saint Augustine, FL, United States
38
3 p.m.
870
260
GENETIC LINKAGE MAPPING IN THE WEST NILE VIRUS VECTOR CULEX TARSALIS
CHARACTERIZING SPECIES DIVERSITY OF VECTORS IMPLICATED IN NON-TRADITIONAL EEE TRANSMISSION IN TENNESSEE
Meera Venkatesan1, Morgan Sellers2, Jason L. Rasgon1
Sudeshna Mukherjee1, Beth Huddleston1, Erin Moody2, Kenneth
Lewockzo2, Ron Wilson3, John Dunn1, Tim F. Jones1, Abelardo C.
Moncayo1
1
Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United
States, 2Johns Hopkins University, Baltimore, MD, United States
1
Tennessee Department of Health, Nashville, TN, United States, 2Union
University, Jackson, TN, United States, 3Tennessee Department of
Agriculture, Nashville, TN, United States
2 p.m.
253
3:15 p.m.
THE ROLE OF FLIGHT TONE CHARACTERISTICS ON MATE
SELECTION OF THE YELLOW FEVER MOSQUITO AEDES
AEGYPTI
1039
TRANSCRIPTOMIC ANALYSIS AND TEMPORAL EXPRESSION
PROFILING OF THE MIDGUT OF THE SAND FLY LUTZOMYIA
LONGIPALPIS IN BLOOD FEEDING AND INFECTION WITH
LEISHMANIA CHAGASI
Lauren J. Cator
Cornell University, Ithaca, NY, United States
2:15 p.m.
Ryan C. Jochim1, Clarissa R. Teixeira2, Regis B. Gomes2, Andre
Laughinghouse2, Dia-eldin Elnaiem2, Jianbing Mu2, Luiz F. Oliveira2,
Jesus G. Valenzuela2
584
MOSQUITOES IN SPACE AND TIME: METEOROLOGIC AND
EDAPHIC FACTORS AFFECTING CULEX TARSALIS ABUNDANCE
IN CALIFORNIA
1
United States, 2National Institute of Allergy and Infectious Diseases,
Rockville, MD, United States
Christopher M. Barker1, William K. Reisen1, Bruce F. Eldridge1,
Wesley O. Johnson2, Jeff Gill1
Young Investigator Award Session C
1
University of California, Davis, CA, United States, 2University of California,
Irvine, CA, United States
Independence III
2:30 p.m.
JUDGES
1027
Roland A. Cooper
A MEANS TO AN END: COMPARATIVE ANALYSIS OF CHROMOSOMAL INVERSIONS FREQUENCY AND DISTRIBUTION IN
THE MAJOR MALARIA VECTORS ANOPHELES GAMBIAE AND
ANOPHELES FUNESTUS ACROSS ECOLOGICALLY DIVERSE
ENVIRONMENTS IN CAMEROON
1
2
3
Old Dominion University, Norfolk, VA, United States
Miriam Laufer
Julian C. Rayner
University of Alabama at Birmingham, Birmingham, AL, United States
4
Diego Ayala , Kenji Ose , Jean Pierre Agbor , Carlo Costantini ,
Nora J. Besansky5, Frederic Simard3, Didier Fontenille1
11 a.m.
1
Institut de Recherche pour le Développement, Unité de Recherche R016,
Montpellier, France, 2Institut de Recherche pour le Développement, Unité de
Service US140, Orleans, France, 3Organisation de coordination pour la lutte
contre les grandes endémies en Afrique centrale, Yaounde, Cameroon,
4
Bobo-dioulasso, Burkina Faso, 5Center for Global Health and Infectious
Diseases, Department of Biological Sciences, University of Notre Dame,
Notre Dame, IN, United States
3
PRIMARY HUMAN SPLENIC MACROPHAGES ARE THE PRINCIPAL TARGET CELLS FOR DENGUE VIRUS INFECTION EX VIVO
Zhihua Kou, Shanley Blackley, Huiyuan Chen, Matthew Quinn,
Robert C. Rose, Jacob J. Schlesinger, Myra Coppage, Xia Jin
University of Rochester, Rochester, NY, United States
2:45 p.m.
11:15 a.m.
1024
1048
A NEW ROBUST DIAGNOSTIC POLYMERASE CHAIN REACTION
(PCR) FOR DETERMINING THE MATING STATUS OF FEMALE
AN. GAMBIAE MOSQUITOES
IDENTIFICATION OF DEVELOPMENTALLY REGULATED GENES
IN ENTAMOEBA HISTOLYTICA
Gretchen M. Ehrenkaufer
Kija R. Ng’habi1, Ashley Horton2, Bart GJ Knols3,
Gregory C. Lanzaro2
Stanford University, Stanford, CA, United States
1
Ifakara Health Research and Development Centre, Morogoro, United
Republic of Tanzania, 2University of California, Davis, CA, United States,
3
Wageningen University and Research Centre, Wageningen, The Netherlands
39
Sunday, November 4
1:45 p.m.
www.astmh.org
Detailed Program
www.astmh.org
11:30 a.m.
12:45 p.m.
776
485
P-GLYCOPROTEIN-LIKE PROTEIN, A PROMISING GENETIC
MARKER TO FOLLOW POTENTIAL IVERMECTIN RESISTANCE IN
ONCHOCERCA VOLVULUS
USE OF GLOBAL PROTEOMICS TO DEFINE PROTEIN PROFILES
OF SEVERE DISEASE: AN INVESTIGATION ON SEVERE
MALARIA
Catherine Bourguinat1, Bernadette F. Ardelli2, Sebastien D. Pion3,
Joseph Kamgno4, Jacques Gardon5, Brian O. Duke6, Michel
Boussinesq7, Roger K. Prichard1
Evelyn N. Gitau
Kenya Medical Research Institute (KEMRI)/Centre for Geographic Medicine
Research (CGMR)-Coas, Kilifi, Kenya
1
Institute of Parasitology, McGill University, Sainte-Anne-de-Bellevue, QC,
Canada, 2Department of Zoology, Brandon University, Brandon, MB,
Canada, 3Laboratoire de Neuroparasitologie et Neuroépidémiologie
Tropicale, Faculté de Médecine, Limoges, France, 4National Onchocerciasis
Task Force Cameroon, Yaounde, Cameroon, 5UR 24 Epidémiologie et
Prévention, Institut de Recherche pour le Développement, La Paz, Bolivia,
6
River Blindness Foundation, Lancaster, United Kingdom, 7UR 24
Epidémiologie et Prévention, Institut de Recherche pour le Développement,
Paris, France
1 p.m.
BREAK
1:30 p.m.
1017
MOLECULAR MARKERS OF THE PATHOGENESIS OF CEREBRAL
MALARIA IN THE MURINE MALARIA PLASMODIUM BERGHEI
11:45 a.m.
Miranda Oakley1, Laurence Faucette1, Victoria Majam2, Hong
Zheng2, Babita Mahajan2, Cindy Erexson1, Jerrold Ward1, Thomas
McCutchan1, Sanjai Kumar2
144
1
National Institute of Allergy and Infectious Diseases, Rockville, MD, United
States, 2FDA, Rockville, MD, United States
THE MAJOR SURFACE PROTEASE OF THE AMASTIGOTE STAGE
OF LEISHMANIA CHAGASI
Chia-Hung Christine Hsiao1, Chaoqun Yao2, Patricia A. Storlie1,
John E. Donelson1, Mary E. Wilson2
1
1:45 p.m.
531
2
University of Iowa, Iowa City, IA, United States, The VA Medical Center
and University of Iowa, Iowa City, IA, United States
DNA MISMATCH REPAIR IN PLASMODIUM FALCIPARUM:
POSSIBLE MECHANISM FOR ACCELERATED DRUG RESISTANCE
Noon
Meryl Castellini, Jeff Buguliskis, Theodore F. Taraschi
147
Thomas Jefferson University, Philadelphia, PA, United States
CHARACTERIZATION OF TRYPANOSOMA BRUCEI CA2+
CHANNNEL: A POTENTIAL DRUG AND VACCINE TARGET IN
TRYPANOSOMES
2 p.m.
533
Kiantra I. Ramey, Nana Wilson, Lucky Nwankwo, Zuzana
Kucerova, Winston Thompson, Jonathan K. Stiles
Morehouse School of Medicine, Atlanta, GA, United States
ASSESSING THE ORIGIN AND SPREAD OF DIHYDROFOLATE
REDUCTASE AND DIHYDROPTEROATE SYNTHASE MUTANT
ALLELES IN PLASMODIUM VIVAX POPULATIONS
12:15 p.m.
Vivian N, Hawkins, Stephanie Suzuki, Carol Hopkins Sibley
1053
University of Washington, Seattle, WA, United States
MULTIPLY PARASITIZED ERYTHROCYTES ARE ASSOCIATED
WITH INCREASED SEVERITY OF MALARIA
2:15 p.m.
300
Lindsey Turnbull1, Nicholas Connors1, Karl Seydel2, Danny Milner3,
Linda Kalilani4, Miriam Laufer5, Christopher Plowe5, Terrie Taylor2
THE ACQUISITION OF INVASION INHIBITORY ANTIBODIES
AND ANTIBODIES TO ERYTHROCYTE INVASION LIGANDS OF P.
FALCIPARUM
1
Blantyre Malaria Project, Blantyre, Malawi, 2College of Osteopathic
Medicine, Michigan State University, East Lansing, MI, United States,
3
Brigham and Women’s Hospital, Boston, MA, United States, 4University of
Malawi College of Medicine, Blantyre, Malawi, 5University of Maryland
School of Medicine, Baltimore, MD, United States
Fiona McCallum1, Kristina Persson1, Cleopatra Mugyenyi2, Linda
Reiling1, Jack Richards1, Tom Williams2, Robin Anders3, Alan
Cowman1, Kevin Marsh2, James Beeson1
1
The Walter and Elisa Hall Institute of Medical Research, Parkville, Australia,
Centre for Geographic Medicine Research, Kenya Medical Research
Institute, Kilifi, Kenya, 3Latrobe University, Melbourne, Australia
12:30 p.m.
2
1057
IMPACT OF ARTMISININ-BASED COMBINATION THERAPY ON
MALARIA TRANSMISSION IN MALI
Bakary Fofana, Adama Dao, Cheick Omar Kone, Bakary Sidibe,
Sekou Toure, Sekou Koumare, Demba Dembele, Abdoulaye Toure,
Ogobara K. Doumbo, Abdoulaye A. Djimde
University of Bamako, Bamako, Mali
40
11 a.m.
320
679
INFECTION-INDUCED CYTOKINE PRODUCTION INFLUENCES
THE SUPPRESSION OF PLASMODIUM YOELII PARASITEMIA
FOLLOWING PROTECTIVE IMMUNIZATION
EVALUATION OF A MICROCOLONY DETECTION METHOD AND
PHAGE ASSAY FOR RAPID DETECTION OF MYCOBACTERIUM
TUBERCULOSIS IN SPUTUM SAMPLES
Patricia M. Petritus, James M. Burns
Seema Irfan
Drexel University College of Medicine, Philadelphia, PA, United States
The Aga Khan University Hospital, Karachi, Pakistan
2:45 p.m.
11:15 a.m.
778
550
THE ROLE OF PFRH INVASION LIGANDS AS TARGETS OF ANTIBODIES THAT PROTECT AGAINST P. FALCIPARUM MALARIA
Linda Reiling1, Jack S. Richards1, Fiona J. MacCallum1, Kristina E.
Persson1, Katherine Howell1, Sam Kinyanjui2, Kevin Marsh2, Ivo
Mueller3, Alan F. Cowman1, James G. Beeson1
WHOLE GENOME AMPLIFICATION AND OLIGONUCLEOTIDE
ARRAY HYBRIDIZATION FOR GENOMIC CHARACTERIZATION
OF FILARIAL PARASITES
Samantha N. Piper
Washington University School of Medicine, St. Louis, MO, United States
1
The Walter and Eliza Hall Institute of Medical Research, Melbourne,
Australia, 2Centre for Geographic Medicine Research, Kenya Medical
Research Institute, Kilifi, Kenya, 3Papua New Guinea Institute of Medical
Research, Goroka, Eastern Highlands Province, Papua New Guinea
11:30 a.m.
133
DEVELOPMENT OF DNA ASSAYS, IN SOIL-TRANSMITTED NEMATODE PARASITES OF HUMANS, FOR THE DETECTION OF SINGLE NUCLEOTIDE POLYMORPHISMS (SNPS) ASSOCIATED
WITH BENZIMIDAZOLE RESISTANCE
3 p.m.
557
SELENIUM LEVELS, MALARIA AND ENDEMIC BURKITTS
LYMPHOMA IN WESTERN KENYA
Aissatou Diawara1, Lesley J. Drake2, Richard R. Suswillo2, Don A.
Bundy3, Roger K. Prichard1
Peter O. Sumba1, Michael Otieno2, Dickens Kowuour1, Chelimo
Kiprotich1, Alloys S. Orago2, Paula Rosenbaum3, Ann M.
Moormann4, Rosemary Rochford3
1
McGill, Montreal, QC, Canada, 2Imperial College School of Medicine,
London, United Kingdom, 3World Bank, Washington DC, WA, United States
1
Kenya Medical Research Institute, Kisumu, Kenya, 2Kenyatta University,
Nairobi, Kenya, 3SUNY Upstate Medical University, Syracuse, NY, United
States, 4Case Western Reserve University, Cleveland, OH, United States
11:45 a.m.
142
ROLE OF MAP KINASE ERK IN ALTERING DENDRITIC CELL
MATURATION AND CELL-MEDIATED IMMUNE RESPONSE TO
LEISHMANIA AMAZONENSIS INFECTION
3:15 p.m.
36
Paola M. Boggiatto, Fei Jei, Rami Mukbel, Mousumi Ghosh,
Douglas E. Jones, Christine A. Petersen
DEVELOPMENTAL ARREST OF MALARIA PARASITES IN MOSQUITOES FOLLOWING TREATMENT OF MICE WITH AS-I-145
Iowa State University, Ames, IA, United States
Lisa A. Purcell1, Stephanie K. Yanow1, Gabriele Pradel2, Ana
Rodriguez3, Moses Lee4, Terry W. Spithill1
1
McGill University, Institute of Parasitology and Centre for Host-Parasite
Interactions, Sainte-Anne-de-Bellevue, QC, Canada, 2University of Würzburg,
Research Center for Infectious Diseases, Würzburg, Germany, 3Department
of Medical Parasitology, New York University School of Medicine, New York,
NY, United States, 4Hope College, Division of Natural and Applied Sciences
and Department of Chemistry, Holland, MI, United States
Noon
143
THE ROLE OF B CELLS IN THE CELL-MEDIATED IMMUNE
RESPONSE TO LEISHMANIA AMAZONENSIS
Katherine N. Gibson-Corley, Rami Mukbel, Christine Petersen,
Douglas Jones
Young Investigator Award Session D
Liberty A
12:15 p.m.
669
JUDGES
EFFECT OF DRUG TREATMENT ON THE DEVELOPMENT
OF CD8+ T CELL MEMORY SUBSETS IN TRYPANOSOMA
CRUZI INFECTION
Christopher L. King
Case Western Reserve University, Shaker Heights, OH, United States
Sanjai Kumar
Juan Bustamante1, Rick Tarleton2
U.S. Food and Drug Administration, Rockville, MD, United States
1
Center for Tropical and Emerging Global Diseases, University of Georgia,
Athens, GA, United States, 2Center for Tropical and Emerging Global
Diseases and Department of Cellular Biology, University of Georgia, Athens,
GA, United States
Peter Zimmerman
41
Sunday, November 4
2:30 p.m.
www.astmh.org
Detailed Program
www.astmh.org
12:30 p.m.
2 p.m.
490
45
THE PLASMODIUM SPOROZOITE AND ERYTHROCYTIC STAGE
(SES) PROTEIN HAS A UNIQUE SURFACE LABELING PATTERN
ON THE SPOROZOITE AND APPEARS TO PLAY A ROLE IN
SPOROZOITE INVASION OF MOSQUITO SALIVARY GLANDS
A NON-ADJUVANTED SELF-ASSEMBLING POLYPEPTIDE
NANOPARTICLE (SAPN) MALARIA VACCINE CONFERS STERILE
PROTECTION TO LETHAL SPOROZOITE CHALLENGE
Stephen A. Kaba1, Clara Brando1, David Tropel2, Peter Burkhard3,
David Lanar1
Alexis N. LaCrue, Roy J. Lowery, Renee N. Roberts, Michael M.
Kariuki, Brenda T. Beerntsen
1
Walter Reed Army Institute of Research, Silver Spring, MD, United States,
M.E. Mueller Institute for Structural Biology, Basel, Switzerland, 3Alpha-O
Peptides AG, Allschwil, Switzerland
2
12:45 p.m.
2:15 p.m.
937
1012
THE IMPACT OF HIV-1 ON THE MALARIA PARASITE BIOMASS
IN SUB-SAHARAN AFRICA AND ITS POSSIBLE CONTRIBUTION
TO THE EMERGENCE AND SPREAD OF ANTIMALARIAL DRUG
RESISTANCE
DEVELOPMENT OF TRANSGENIC PLASMODIUM BERGHEI
EXPRESSING P. FALCIPARUM SEXUAL ANTIGEN PFS25 FOR IN
VIVO ASSESSMENT OF TRANSMISSION BLOCKING IMMUNITY
Godfree Mlambo, Jorge Maciel, Nirbhay Kumar
Jean-Pierre Van geertruyden1, Joris Menten1, Robert
Colebunders1, Eline Korenromp2, Umberto D’Alessandro1
Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD,
United States
1
Prince Leopold Instituut voor Tropische Geneeskunde, Antwerpen, Belgium,
2
Department of Public Health, University Medical Centre Rotterdam,
Rotterdam, The Netherlands
2:30 p.m.
43
1 p.m.
BREAK
REPRODUCIBILITY OF A SPOROZOITE CHALLENGE MODEL FOR
PLASMODIUM VIVAX IN HUMAN VOLUNTEERS
1:30 p.m.
Johanna A. Parra1, Leonardo Rocha2, Ricardo Palacios3, Juan
Diego Velez4, Judith Epstein5, Tom Richie6, Myriam Arevalo-Herrera1,
Socrates Herrera1
703
IMPACT OF MATERNAL MALARIA AND UNDER-NUTRITION ON
INTRAUTERINE GROWTH RESTRICTION: A PROSPECTIVE
COHORT STUDY IN DEMOCRATIC REPUBLIC OF CONGO
1
Malaria Vaccine and Drug Testing Center, Cali, Colombia, 2Immunology
Institute, Cali, Colombia, 3Praca Marisa Marques-University Sao Pablo,
Sao Pablo, Brazil, 4Fundación Clínica Valle de Lili, Cali, Colombia, 5Malaria
Program, Naval Medical Research Center, Silver Spring, MD, United States,
6
Malaria Program, Naval Medical Research Center, Silver Spring, MD,
United States
Sarah Landis1, Victor Lokomba2, Joseph Atibu2, Cande Ananth3,
Robert Ryder4, Katherine Hartmann5, John Thorp1, Antoinette
Tshefu2, Steven Meshnick1
1
UNC-Chapel Hill, Chapel Hill, NC, United States, 2UNC-DRC Project,
Kinshasa, Democratic Republic of the Congo, 3University of Medicine and
Dentistry of New Jersey-Robert Wood Johnson Medical School, New
Brunswick, NJ, United States, 4Boston University School of Public Health,
Boston, MA, United States, 5Vanderbilt University Medical Center, Nashville,
TN, United States
2:45 p.m.
14
DYNAMICS OF POLYMORPHISM IN PLASMODIUM FALCIPARUM APICAL MEMBRANE ANTIGEN-1 OVER THREE YEARS
AT A VACCINE-TESTING SITE IN MALI
1:45 p.m.
Shannon Takala1, Amed Ouattara1, Drissa Coulibaly2, Mahamadou
A. Thera2, Alassane Dicko2, Ando B. Guindo2, Abdoulaye K. Kone2,
Karim Traore2, Abdoulaye Djimde2, Kirsten E. Lyke1, Dapa A. Diallo2,
Ogobara K. Doumbo2, Christopher V. Plowe1
199
B CELL ACTIVITY IN CHILDREN WITH SEVERE
MALARIAL ANEMIA
1
2
1
University of Maryland School of Medicine, Baltimore, MD, United States,
Malaria Research and Training Center, University of Bamako, Bamako, Mali
2
1
Jackson C. Korir , Ronald P. Taylor , John N. Waitumbi
1
Walter Reed Project/KEMRI, Kisumu, Kenya, 2Department of Biochemistry
and Molecular Genetics, University of Virginia School of Medicine,
Charlottesville, VA, United States
42
11:30 a.m.
38
98
PLASMODIUM FALCIPARUM GENETIC STRUCTURE IN THE
FOUR MAJOR AFRICAN ANOPHELES VECTORS
IMMUNIZATION WITH LEPTOSPIRAL IMMUNOGLOBULIN-LIKE
(LIG) PROTEIN WITH ALUMINIUM HYDROXIDE ADJUVANT
CONFERS STERILIZING IMMUNITY IN THE HAMSTER MODEL
FOR LEPTOSPIROSIS
Zeinab Annan1, Patrick Durand1, Parfait Awono-Ambene2, Frédéric
Simard2, Céline Arnathau1, François Renaud1, Didier Fontenille3
1
Flavia W. McBride1, Marco Medeiros2, Alan J. McBride1, Claudio P.
Figueira1, Gabriela Esteves2, Adenizar Chagas Júnior1, Cleiton
Santos1, James Matsunaga3, David Haake3, Akira Homma2, Ricardo
Galler2, Mitermayer G. Reis1, Albert I. Ko4
Centre National de la Recherche Scientifique/Institut de Recherche pour le
Développement, Montpellier, France, 2Institut de Recherche pour le
Développement, Organisation de lutte Contre les Endémies en Afrique
Centrale, Yaoundé, Cameroon, 3Institut de Recherche pour le
Développement, Montpellier, France
1
Oswaldo Cruz Foundation, Salvador, Brazil, 2Oswaldo Cruz Foundation, Rio
de Janeiro, Brazil, 3School of Medicine, University of California at Los
Angeles, Los Angeles, CA, United States, 4Weil Medical College of Cornell
University, New York, NY, United States
3:15 p.m.
100
MALARIA TRANSMISSION INTENSITY AND MORBIDITY
PATTERNS IN PARTS OF THE IMO RIVER BASIN, SOUTH
EASTERN NIGERIA
11:45 a.m.
Uchechukwu M. Chukwuocha1, Ikechi N. Dozie2, Betram E.
Nwoke2, Celestine O. Onwuliri1, Okwuoma C. Abanobi1
EFFICACY OF PYRVINIUM PAMOATE AGAINST
CRYPTOSPORIDIUM PARVUM INFECTION IN VITRO AND IN A
NEONATAL MOUSE MODEL
961
1
Federal University of Technology, Owerri, Nigeria, 2Imo State University,
Owerri, Nigeria
Autumn S. Girouard1, David J. Sullivan1, Curtis R. Chong2,
Thaddeus K. Graczyk1
1
States, 2Johns Hopkins University School of Medicine, Baltimore, MD,
United States
Young Investigator Award Session E
Liberty C
Noon
JUDGES
631
Joseph M. Vinetz
KILLED BUT METABOLICALLY ACTIVE (KBMA) LEISHMANIA - A
NOVEL PROTOZOAN VACCINE TECHNOLOGY FOR VISCERAL
LEISHMANIASIS THAT IS ENHANCED BY TOLL-LIKE RECEPTOR
ACTIVATION
University of California at San Diego, La Jolla, CA, United States
David Williams
Illinois State University, Normal, IL, United States
Yimin Wu
Ron A. Birnbaum, Stephanie Greger, Thu A. Tran, Jacquelyn N.
Haskell, Rupa Narayan, Pei L. Cheng, Kevin W. Bruhn, Noah Craft
Diseases, Rockville, MD, United States
Los Angeles Biomedical Research Institute, Division of Dermatology,
Harbor-UCLA Medical Center, UCLA School of Medicine, Torrance, CA,
United States
11 a.m.
762
12:15 p.m.
THE ROLE OF T CELLS IN DENGUE VIRUS INFECTION
648
Lauren E. Yauch, Sujan Shresta
HUMAN DEFENSIN α-1 KILLS TRYPANOSOMA CRUZI VIA
MEMBRANE PORE FORMATION LEADING TO APOPTOSIS
La Jolla Institute for Allergy and Immunology, La Jolla, CA, United States
11:15 a.m.
M. Nia Madison, Yuliya Kleshchenko, Pius Nde, Kaneatra
Simmons, Maria F. Lima, Fernando Villalta
372
Meharry Medical College, Nashville, TN, United States
STRAIN CHARACTERISATION OF HUMAN HYDATIDOSIS IN
SUDAN
12:30 p.m.
Rihab A. Omer1, Anke Dinkel2, Thomas Romig2, Ute
Mackenstedt2, Mohamed Elamin3, Ayman Elnahas4, Imad Aradaib4
1
314
2
NEUTROPHILS DOMINATE THE EARLY INFLAMMATORY
RESPONSE DURING ACUTE INTRADERMAL INFECTION WITH
LEISHMANIA CHAGASI
Central Veterinary Research Laboratories, Khartoum, Sudan, Institute of
Prasitology. University of Hohenehim, Stuttgart, Germany, 3Elshab Teaching
Hospital, Khartoum, Sudan, 4Faculty of Veterinary Medicine, University of
Khartoum, Khartoum, Sudan
Colin J. Thalhofer1, A. Paige Davis1, Mary E. Wilson2
1
University of Iowa, Iowa City, IA, United States, 2University of Iowa, VA
Medical Center, Iowa City, IA, United States
43
Sunday, November 4
3 p.m.
www.astmh.org
Detailed Program
www.astmh.org
2:30 p.m.
12:45 p.m.
556
1016
TEMPORAL STABILITY OF BLOOD STAGE MALARIA IMMUNE
SURROGATES OF PROTECTION IN A MALARIA HOLOENDEMIC
AREA
APOPTOSIS STALKS AN EXPONENTIALLY GROWING
PLASMODIUM FALCIPARUM CULTURE
Beth K. Mutai, John N. Waitumbi
Walter Reed Project/Kenya Medical Research Institute, Kisumu, Kenya
Arlene E. Dent1, Kiprotich Chelimo2, Peter Sumba2, Daniel Tisch1,
Michele Spring3, Ann Moormann1, James Kazura1
1 p.m.
1
Case Western Reserve University, Cleveland, OH, United States, 2Kenya
Medical Research Institute, Kisumu, Kenya, 3Walter Reed Army Institute of
Research, Washington, DC, United States
BREAK
1:30 p.m.
2:45 p.m.
809
364
ENHANCED DETECTION OF GAMETOCYTES PREDICTS HIGHER
POTENTIAL FOR PLASMODIUM FALCIPARUM TRANSMISSION
PLASMODIUM SPOROZOITES LACKING AN ASPARAGINE RICH
PROTEIN FAIL TO ESTABLISH LIVER STAGE INFECTION AND
ELICIT STERILE IMMUNITY AGAINST MALARIA
Stephan Karl1, Brian T. Grimberg2, Lee R. Moore3, Makindi David4,
Pascal Michon4, Ivo Mueller5, Maciej Zborowski3, Peter A.
Zimmerman2
Ahmed S. Aly, Stefan H. Kappe
Seattle Biomedical Research Institute, Seattle, WA, United States
1
University of Technology Dresden, Dresden, Germany, 2The Center of
Global Health and Disease, Case Western Reserve University, Cleveland, OH,
United States, 3Cleveland Clinics, Lerner Research Institute, Department of
Biomedical Engineering, Cleveland, OH, United States, 4Molecular
Parasitology Unit, Molecular Parasitology Unit, Institute of Medical Resarch
Papua New Guinea, Madang, Papua New Guinea, 5Vector Borne Diseases,
Goroka, Papua New Guinea
3 p.m.
365
TO LIVE OR DIE: INVESTIGATING THE ROLE OF PLASMODIUM
FALCIPARUM MITOCHONDRIA IN THE FACE OF ELECTRON
TRANSPORT INHIBITION
1:45 p.m.
Heather J. Painter, Joanne M. Morrisey, Akhil B. Vaidya
939
AMPLIFICATION OF THE PFMDR1 LOCUS IN PLASMODIUM
FALCIPARUM IS LINKED TO PLEIOTROPIC TRANSCRIPTIONAL
REGULATION
3:15 p.m.
352
Joseph M. Gonzales1, Jigar J. Patel1, Napawan Ponmee2, Lei
Jiang2, Pradip K. Rathod2, Michael T. Ferdig1
1
PREDICTORS OF ANTICONVULSANT TREATMENT FAILURE
AMONG CHILDREN WITH SEVERE MALARIA
2
University of Notre Dame, Notre Dame, IN, United States, University of
Washington, Seattle, WA, United States
Arthur Mpimbaza1, Sarah Staedke2, Grace Ndeezi1, Justus
Byarugaba1, Philip J. Rosenthal3
2 p.m.
1
Makerere University, Kampala, Uganda, 2London School of Hygiene and
Tropical Medicine, London, United Kingdom, 3University of California San
Francisco, San Francisco, CA, United States
695
TLR9 POLYMORPHISMS ARE ASSOCIATED WITH ALTERED
IFN- LEVELS IN CHILDREN WITH CEREBRAL MALARIA
ACAV SIE Subcommittee Meeting
Nadia A. Sam-Agudu1, Jennifer Greene2, Robert O. Opoka3,
James W. Kazura2, Michael J. Boivin4, Lisa A. Schimmenti1, Peter A.
Zimmerman2, Chandy C. John1
Room 309
Sunday, November 4, 2007 11 a.m. - Noon
1
University of Minnesota Children’s Hospital-Fairview, Minneapolis, MN,
United States, 2Case Western Reserve University, Cleveland, OH, United
States, 3Makerere University, Kampala, Uganda, 4Michigan State University,
East Lansing, MI, United States
ACAV SIRACA Subcommittee Meeting
Room 309
Sunday, November 4, 2007 Noon - 2 p.m.
2:15 p.m.
323
ACAV SALS Subcommittee Meeting
COMPLEMENT UTILIZATION IN CHILDREN WITH SEVERE
MALARIA ANEMIA
Room 309
Sunday, November 4, 2007 2 p.m. - 3:30 p.m.
Nancy K. Nyakoe1, John N. Waitumbi1, Ron P. Taylor2
1
Walter Reed Project/Kenya Medical Research Institute, Kisumu, Kenya,
Department of Biochemistry and Molecular Genetics, University of Virginia
School of Medicine, Charlottesville, VA, United States
Young Investigator Committee Meeting
2
Independence I
Sunday, November 4, 2007 3:30 p.m. - 5 p.m.
44
ACME Council Meeting
www.astmh.org
AMERICAN COMMITTEE OF MEDICAL ENTOMOLOGY (ACME)
TRAVEL AWARDS
Room 301
Edward D. Walker
Michigan State University, East Lansing, MI, United States
ACAV Council Meeting
YOUNG INVESTIGATOR AWARDS
Peter Zimmerman
Room 309
Sunday, November 4, 2007 3:30 p.m. - 5:30 p.m.
ROBERT E. SHOPE INTERNATIONAL FELLOWSHIP IN
INFECTIOUS DISEASES
ACMCIP Council Meeting
Charles Calisher
Room 362
Colorado State University, Fort Collins, CO, United States
GORGAS MEMORIAL INSTITUTE RESEARCH AWARD
Rebeca Rico-Hesse
Southwest Foundation for Biomedical Research, San Antonio, TX,
United States
Room 405
BURROUGHS WELLCOME FUND - ASTMH POSTDOCTORAL
FELLOWSHIP IN TROPICAL INFECTIOUS DISEASES
Student Reception
Terrie Taylor
Michigan State University, East Lansing, MI, United States
Porthole Room across Bridge on Third Floor
PFIZER CENTENNIAL TRAVEL AWARD IN BASIC SCIENCE
TROPICAL DISEASE RESEARCH
Sunday, November 4, 2007 4 p.m. - 5 p.m.
The ASTMH council invites students, postdoctoral fellows and residents to
the student reception. This reception is an opportunity to meet fellow
trainees and interact with society leaders.
Joseph M. Vinetz
BENJAMIN H. KEAN TRAVELING FELLOWSHIP IN TROPICAL
MEDICINE
Plenary Session I and Society Awards
Ceremony
Christopher V. Plowe
University of Maryland School of Medicine, Baltimore, MD, United States
Salon GH
COMMUNICATIONS AWARD
CHAIR
Claire Panosian
UCLA School of Medicine, Los Angeles, CA, United States
PATH Malaria Control and Evaluation Partnership in Africa (MACEPA),
Seattle, WA, United States
HONORARY MEMBERS
Edward T. Ryan
Imperial College Science Technology and Medicine, London,
United Kingdom
Robert Sinden
Massachusetts General Hospital, Boston, MA, United States
Presented by Daniel J. Carucci
5:30 p.m.
Foundation for the National Institutes of Health, Bethesda, MD,
United States
PERSPECTIVES IN GLOBAL HEATH
Tadataka Yamada, MD
President, Global Health Program
Robert Swanepoel
National Institute for Communicable Diseases, Johannesburg, South Africa
Presented by Thomas Ksiazek
6:30 p.m.
AWARDS CEREMONY
SCHERER/HARDY AWARD
Hosted by Carlos C. (Kent) Campbell
Introduction by Douglas M. Watts
ASTMH TRAVEL AWARDS
Bruce Eldridge
James LeDuc
University of California at Davis, Davis, CA, United States
HOOGSTRAAL MEDAL
Presented by Stephen Higgs
45
Sunday, November 4
www.astmh.org
Detailed Program
Meet the Professors 2
BAILEY K. ASHFORD MEDAL
Michael Cappello
Yale University School of Medicine, New Haven, CT, United States
The George Washington University, Washington, DC, United States
Meet the Professors A: Fireside Chat: Personal
Experiences, Words of Wisdom and Institutional
Perspectives
BEN KEAN MEDAL
Salon G
Robert Gilman
Monday, November 5, 2007 7 a.m. - 8 a.m.
Presented by Peter J. Hotez
Johns Hopkins University School of Public Health, Baltimore, MD,
United States
Designed for students and trainees as the next generation of tropical medicine leaders, a panel of professors will share information on their institutions, programs, career development and research opportunities. A light
breakfast will be served.
Presented by Frank Bia
DONALD MACKAY MEDAL
David Molyneux
CHAIR
Liverpool School of Tropical Medicine, Liverpool, United Kingdom
Ottawa Hospital, Ottawa, ON, Canada
Presented by Peter J. Hotez
PANELISTS
Alan Magill
Anne McCarthy
Walter Reed Army Institute of Research, Silver Spring, MD, United States
Opening Reception
Edward T. Ryan
Franklin Hall
Symposium 2A
Monday, November 5
Artemether/Lumefantrine Dispersible - ACT Addressing
Children Therapeutic Needs
Registration
Supported with funding from Novartis Pharma AG.
Organizational Support provided by Medicines for
Malaria Venture
Monday, November 5, 2007 7 a.m. - 5 p.m.
Salon AB
Cyber Cafe
Monday, November 5, 2007 8 a.m. - 9:45 a.m.
Franklin Hall Foyer
Malaria is primarily a disease of infants and young children. However, there
are currently no safe and effective antimalarials specifically formulated for
this vulnerable population that are registered to a stringent international
standard and recommended by WHO. To address this critical gap, an innovative formulation of the effective fixed-dose formulation of the ACT,
artemether/lumefantrine, has been developed. This proved a surprisingly
challenging task. Not only did the new formulation have to be as safe and
effective as the current tablet formulation, it also had to meet stringent
requirements deemed essential for widespread use including palatability, stability and critically, affordability. This symposium will focus on the clinical
aspects of the dispersible tablet development program.
Speaker Ready Room
Rooms 413-415
Press Room
Rooms 403-404
CHAIR
Monday, November 5, 2007 7:30 a.m. - 6:30 p.m.
Umberto D’Alessandro
ASTMH Public Policy and Advocacy Leadership
Committee Meeting
Prince Leopold Institute of Tropical Medicine, Antwerp, Belgium
Room 305
ARTEMETHER/LUMEFANTRINE CRUSHED TABLET - A CLINICAL
OVERVIEW
8 a.m.
Michael M. Makanga
European and Developing Countries Clinical Trials, Cape Town, South Africa
Room 410
46
8:15 a.m.
8 a.m.
PUBLIC-PRIVATE PARTNERSHIP DEVELOPS THE NEW
STANDARD OF CARE FOR PEDIATRIC MALARIA PATIENTS:
RATIONALE FOR DEVELOPING A DISPERSIBLE TABLET
THE TICK ENCOUNTER RESOURCE CENTER
www.astmh.org
Thomas N. Mather
Medicines for Malaria Venture, Geneva, Switzerland
8:25 a.m.
8:25 a.m.
DECISION SUPPORT SYSTEMS FOR CONTROL OF
CHAGAS DISEASE
EARLY DEVELOPMENT STEPS OF THE
ARTEMETHER/LUMEFANTRINE DISPERSIBLE TABLET:
PHARMACOKINETICS AND PALATABILITY
Uriel Kitron
Salim Abdulla
8:45 a.m.
Ifakara Health Research and Development Centre, Dar-es-Salaam, United
Republic of Tanzania
ROSS RIVER VIRUS EARLY DETECTION AND SURVEILLANCE
SYSTEM
8:40 a.m.
Peter Ryan
University of Illinois at Urbana-Champaign, Urbana, IL, United States
Queensland Institute of Medical Research, Brisbane, Australia
EFFICACY OF ARTEMETHER/LUMEFANTRINE DISPERSIBLE
TABLE - PHASE III RESULTS
9:05 a.m.
Bernhards R. Ogutu
MALARIA DECISION SUPPORT SYSTEM PROJECT
Centre for Clinical Research, Kenya Medical Research Institute,
Kisumu, Kenya
Michael Coleman
Medical Research Council, Durban, South Africa
9 a.m.
9:25 a.m.
SAFETY AND TOLERABILITY OF ARTEMETHER/LUMEFANTRINE
DISPERSIBLE TABLET - PHASE III RESULTS
DENGUE DECISION SUPPORT SYSTEM PROJECT
Lars Eisen
Philip G. Sasi
KEMRI/Wellcome Trust Research Programme, Kilifi, Kenya
9:25 a.m.
Symposium 5
QUESTION AND ANSWER PERIOD
Immunoparasitology (ACMCIP): Genomic Approaches
to Host and Parasite Interactions
Symposium 3
Information System and Decision Support System
Approaches to Facilitate Control of Vector-Borne
Diseases
Supported with funding from The Burroughs Wellcome Fund
Salon F
Salon CD
This symposium is designed to review and update progress on the use of
genomic approaches to investigate parasite and host interactions. The
speakers will discuss topics ranging from population genetic approaches to
natural selection, expression arrays and RNAi methodologies to look at hostparasite interactions. The symposium will highlight examples of genomic
approaches that can be applied to the question of host-parasite interactions
in a variety of parasitic diseases.
The symposium will focus on the use of computer-based information and
decision support systems as new tools to facilitate: 1) operational vector and
disease surveillance and control activities; and 2) transfer of evidence-based
information from the scientific community to the parties de facto responsible for vector and disease control. The symposium aims to 1) generate a discussion of the problems and possibilities related to information and decision
support system approaches to facilitate control of vector-borne diseases;
and 2) synergize the formation of an international working group charged
with harmonization of existing decision support systems for vector-borne
diseases and exploration of the potential for combination systems capable
of supporting surveillance and control of multiple vector-borne diseases.
CHAIR
Sarah K. Volkman
Harvard School of Public Health, Boston, MA, United States
8 a.m.
CHAIR
NATURAL SELECTION IN HUMANS AND MALARIA
Lars Eisen
Pardis C. Sabeti
The Broad Institute of MIT and Harvard, Cambridge, MA, United States
8:35 a.m.
TOXOPLASMA INFECTION AND HOST GENE EXPRESSION
Jon Boyle
47
Monday, November 5
University of Rhode Island, Kingston, RI, United States
Christopher Hentschel
Detailed Program
www.astmh.org
9:10 a.m.
8:45 a.m.
4
HELMINTH INFECTION AND HOST IMMUNITY
Murray Selkirk
WHOLE BLOOD TRANSCRIPTIONAL PROFILES ASSOCIATION
WITH DENGUE SHOCK SYNDROME
Imperial College London, London, United Kingdom
Long T. Hoang
Scientific Session 6
The Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam
9 a.m.
Flavivirus I - Dengue I
5
Salon G
Daniel Libraty
DIFFERENTIAL AND TEMPORAL MODULATION OF
ENDOTHELIAL BARRIER FUNCTION BY HEMORRHAGIC
FEVER VIRUSES
University of Massachusetts Medical School, Worcester, MA, United States
Ping Liu, Daniel H. Libraty
CHAIR
Sujan Shresta
LIAI, La Jolla, CA, United States
(ACMCIP Abstract)
8 a.m.
9:15 a.m.
1
6
GLYCOSYLATION OF THE DENGUE 2 VIRUS E PROTEIN AT N67
IS CRITICAL FOR VIRUS GROWTH IN VITRO BUT NOT FOR
GROWTH IN INTRATHORACICALLY-INOCULATED AEDES
AEGYPTI MOSQUITOES
DEVELOPING A MOUSE MODEL OF DENGUE
IMMUNOPATHOGENESIS
Scott Balsitis, Jennifer L. Kyle, Diana Flores, P. Robert Beatty,
Eva Harris
John T. Roehrig1, Juliet E. Bryant2, Amanda E. Calvert1, Kyeen
Mesesan1, Mary B. Crabtree1, Katharine E. Volpe1, Shawn Silengo1,
Richard M. Kinney1, Claire Y. Huang1, Barry R. Miller1
Division of Infectious Diseases, School of Public Health, University of
California, Berkeley, Berkeley, CA, United States
1
Arboviral Diseases Branch, Division of Vector-Borne Infectious Diseases,
National Center for Infectious Diseases, Centers for Disease Control and
Prevention, U.S. Department of Health and Human Services, Fort Collins,
CO, United States, 2Institute Pasteur, Vientiane, Lao People’s Democratic
Republic
9:30 a.m.
7
DENGUE VIRAL DETERMINANTS OF SEVERE DISEASE IN MICE
Tyler R. Prestwood, Daniil M. Prigozhin, Kristin L. Sharar, Lauren E.
Yauch, Sujan Shresta
8:15 a.m.
2
HIGHER FREQUENCY OF DENGUE VIRAL RNA DETECTED IN
PLATELETS THAN IN PLASMA IN THE LATE STAGE OF DENGUE
VIRUS INFECTION
Symposium 7
Sansanee Noisakran1, Robert Gibbons2, Pucharee Songprakhon1,
Aroonroong Jairungsri1, Chuanpis Ajariyakhajorn2, Ananda Nisalak2,
Richard Jarman2, Mammen Mammen2, Kulkanya Chokephaibulkit1,
Prida Malasit1, Guey Perng2
Monitoring and Evaluation Issues with Regard to
Integrated Control of Neglected Tropical Diseases
(NTDs)
1
Salon H
Medical Molecular Biology Unit, Office for Research and Development,
Siriraj Hospital, Bangkok, Thailand, 2Armed Forces Research Institution for
Medical Sciences, Bangkok, Thailand
During this symposium we will present selected results and achievements
from current vertical programs of NTDs (schistosomiasis, lymphatic filariasis,
intestinal helminths and onchocerciasis) already in place from several African
countries. We will update on progress as regards to the planning for monitoring and evaluation of expected future integrated programs against these
infections. We will discuss issues on the design of these studies, what to
measure, costs, sample sizes and frequency of follow-up. Evaluation plans
will have to be designed to address the specific questions raised by the
donors, local partners and implementers, and provide robust epidemiological evidence of any increased effect and cost effectiveness attributable to
integration of NTD control.
8:30 a.m.
3
PRIMARY HUMAN SPLENIC MACROPHAGES ARE THE PRINCIPAL TARGET CELLS FOR DENGUE VIRUS INFECTION EX VIVO
Zhihua Kou, Shanley Blackley, Huiyuan Chen, Matthew Quinn,
Robert C. Rose, Jacob J. Schlesinger, Myra Coppage, Xia Jin
University of Rochester, Rochester, NY, United States
CHAIR
Alan Fenwick
Imperial College, London, United Kingdom
48
www.astmh.org
Symposium 9
Peter J. Hotez
Measuring Disability Due to Chronic Infection: The
Hidden Costs of Cystic Echinococcosis
8 a.m.
MONITORING AND EVALUATION OF NTDS
Salon KL
Joanne P. Webster
This symposium is designed to review and update current knowledge of the
human health and agriculture-related costs associated with cystic echinococcosis (CE). Methods to ascertain both financial and non-financial burden
estimates will be discussed as will the need for improved reporting.
8:35 a.m.
EAST AFRICAN EXPERIENCES – UGANDA
Narcis Kabatereine
Ministry of Health, Kampala, Uganda
CHAIR
Enrico Brunetti
9:10 a.m.
University of Pavia, Pavia, Italy
WEST AFRICAN EXPERIENCES – NIGER AND BURKINA FASO
CO-CHAIR
Amadou Garba
Paul R. Torgerson
Ministry of Health, Niamey, Niger
University of Zürich, Zürich, Switzerland
Symposium 8
8 a.m.
HIV in the Tropics
MEASURING THE BURDEN OF PARASITIC ZOONOSES: PROS
AND CONS OF THE DALYS APPROACH
Salon IJ
Hélène Carabin
University of Oklahoma, Oklahoma City, OK, United States
This symposium will review the most recent data and patterns of the burden
of HIV in the tropics. A general overview of the epidemiology of HIV will
introduce this topic, co-infection with pertinent tropical diseases and emerging opportunistic infections will be examined, the role and development of
anti retroviral therapy will be discussed with a focus on Sub-Saharan Africa
and the symposium will end with a review of the HIV-positive traveler and
pre/post-travel considerations.
8:25 a.m.
ECHINOCOCCOSIS: FROM BURDEN ESTIMATES TO COSTEFFECTIVENESS
Paul R. Torgerson
University of Zürich, Zürich, Switzerland
CHAIR
8:50 a.m.
John D. Cahill
TOWARDS ESTIMATING THE NON-MONETARY BURDEN OF
CYSTIC ECHINOCOCCOSIS
St. Luke’s/Roosevelt Hospital, New York, NY, United States
Christine M. Budke
Maria Mileno
Texas A&M University, College Station, TX, United States
Brown University, Providence, RI, United States
9:15 a.m.
8 a.m.
ON THE HUNT FOR CE IN A MOROCCAN VILLAGE:
THE CHALLENGES OF IDENTIFYING SURGICAL CASES
IN ENDEMIC REGIONS
AN OVERVIEW OF HIV IN THE TROPICS
Jennifer Stratton
St. Luke’s Roosevelt Hospital Center, New York, NY, United States
Malika Kachani of Veterinary Medicine, Pomona, CA, United States
8:20 a.m.
Symposium 10
THE BURDEN OF TROPICAL DISEASES ON HIV
John Cahill
St. Luke’s/Roosevelt Hospital, New York, NY, United States
Tropical Medicine and the Media
8:50 a.m.
Liberty AB
ANTIRETROVIRAL USE IN THE TROPICS
Newspaper and magazine articles, as well as broadcast and Web-based journalism, can have a powerful impact on the public’s understanding of poverty, health and neglected diseases. Each year, ASTMH features a panel
exploring current trends in tropical medicine journalism and advocacy. This
year’s panelists will discuss, among other topics, the awakening interest in
tropical diseases, global health and social justice by the American public.
The session will conclude with audience questions and answers.
Nayomi Sajan
St. Luke’s Roosevelt Hospital Center, New York, United States
9:15 a.m.
THE HIV-POSITIVE TRAVELER
Maria Mileno
49
Monday, November 5
Imperial College Faculty of Medicine, London, United Kingdom
www.astmh.org
Detailed Program
8 a.m.
CHAIR
Claire Panosian
8
A FOUR-YEAR FOLLOW-UP OF THE SAFETY, IMMUNOGENICITY AND EFFICACY OF THE CANDIDATE MALARIA VACCINE
RTS,S/AS02A IN CHILDREN VACCINATED AT AGED 1 TO 4
YEARS IN A MALARIA-ENDEMIC REGION OF MOZAMBIQUE
8 a.m.
INTRODUCTION
Claire Panosian
John J. Aponte1, Jahit Sacarlal2, Pedro Aide2, Eusebio Macete2,
Montse Renom1, Quique Bassat1, Inacio Mandomando2, Maria N.
Manaca2, Sarah Lafuente1, Amanda Leach3, Ripley Ballou3, Marc
Lievens3, Joelle Thonnard3, Marie-Claude Dubois3, Marie-Ange
Demotie3, Joe Cohen3, Filip Dubovsky4, Jessica Millman4, Marla
Sillman4, Pedro L. Alonso1
8:10 a.m.
FROM AMERICAN POVERTY TO MALARIA:
THE JOURNEY OF A WASHINGTON POST REPORTER
Michael Leahy
1
Barcelona Centre For International Health Research (CRESIB), Hospital
Clinic/IDIBAPS, University of Barcelona, Barcelona, Spain, 2Manhiça Health
Research Centre (CISM), Manhiça, Mozambique, 3GlaxoSmithKline
Biologicals, Rixensart, Belgium, 4PATH Malaria Vaccine Initiative, Bethesda,
MD, United States
The Washington Post, Washington, DC, United States
8:30 a.m.
GLOBAL HEALTH ADVOCACY: LESSONS FROM THE GATES
FOUNDATION AND BONO “ONE” CAMPAIGN
8:15 a.m.
Joe Cerrell
9
Bill and Melinda Gates Foundation, Seattle, WA, United States
ASSESSMENT OF CELLULAR IMMUNE RESPONSES IN INFANTS
PARTICIPATING IN A RTS,S/AS02D PHASE I/IIB TRIAL IN
MOZAMBIQUE
8:50 a.m.
COVERING TROPICAL MEDICINE AT NPR
Joanne Silberner
Arnoldo Barbosa1, Denise Naniche1, Maria N. Manaca2, John
Aponte1, Inacio Mandomando2, Pedro Aide2, Montse Renom1, Jahit
Sacarlal2, Ripley Ballou3, Philippe Moris3, Joe Cohen3, Filip
Dubovsky4, Jessica Millman4, Pedro L. Alonso1
National Public Radio, Washington, DC, United States
9:10 a.m.
1
Barcelona Centre For International Health Research (CRESIB), Hospital Clinic/
IDIBAPS, University of Barcelona, Barcelona, Spain, 2Manhiça Health
Research Centre (CISM), Manhiça, Mozambique, 3Glaxo-SmithKline
MD, United States
WORKING WITH THE MEDIA
Frank Richards
The Carter Center, Atlanta, GA, United States
(ACMCIP Abstract)
Malaria - Vaccines I
8:30 a.m.
10
Liberty C
A RANDOMIZED, OBSERVER-BLIND TRIAL TO COMPARE SAFETY AND IMMUNOGENICITY OF TWO ADJUVANTED RTS,S
ANTI-MALARIA VACCINE CANDIDATES IN GABONESE CHILDREN
CHAIR
Bertrand Lell
Albert Schweitzer Hospital, Lambarene, Gabon
Bertand Lell1, Selidji Agnandji1, Isabelle von Glasenapp1, Sunny
Oyakhiromen1, Sonja Haertle1, Peter G. Kremsner1, Isabelle
Ramboer2, Marc Lievens2, Ripley Ballou2, Johan Vekemans2, MarieClaude Dubois2, Marie-Ange Demoitie2, Joe Cohen2, Tonya
Villafana3, Terrell Carter3, Carolyn Petersen3
Shannon Takala
1
Medical Research Unit, Albert Schweitzer Hospital, Lambaréné, Gabon,
GlaxoSmithKline Biologicals, Rixensart, Belgium, 3PATH Malaria Vaccine
Initiative, Bethesda, MD, United States
2
50
www.astmh.org
8:45 a.m.
11
Bacteriology I - Diarrhea, Enteric Infections and Other
SAFETY AND TOLERABILITY OF A MULTI-STAGE, MULTI-ANTIGEN ADENOVIRUS-VECTORED P. FALCIPARUM MALARIA
VACCINE, IN HEALTHY, MALARIA-NAÏVE ADULTS
Franklin 2
David P. Regis1, Martha Sedegah1, Jose Mendoza-Silveiras1,
Victoria Steinbeiss1, Sharina Reyes1, Judith E. Epstein1, Ilin Chuang,
Francis Williams1, Gail L. Levine2, Joseph T. Bruder3, C. Richter
King3, Noelle B. Patterson1, Keith Limbach1, Lorraine Soisson4,
Carter Diggs4, Denise L. Doolan1, Thomas Richie1
CHAIR
Eric Mintz
Paola A. Torres
Naval Medical Research Center Detachment-Peru, Lima, Peru
1
Naval Medical Research Center, Silver Spring, MD, United States,
2
Foundation for the National Institutes of Health, Bethesda, MD, United
States, 3GenVec, Inc., Gaithersburg, MD, United States, 4United States
Agency for International Development, Malaria Vaccine Development
Program, Washington, DC, United States
8 a.m.
15
RISK FACTORS FOR DIARRHEAL DISEASE MORTALITY AMONG
HOSPITALIZED CHILDREN IN RURAL WESTERN KENYA, 20052007
9 a.m.
12
Ciara E. O’Reilly1, Jacqueline Tate1, Eileen Yee1, Elizabeth Blanton1,
Benjamin Ochieng2, Peter Jaron2, Amek Nyaguara2, Michele
Parsons1, Cheryl Bopp1, John Vulule3, Robert Breiman4, Daniel
Feikin2, Kayla Laserson2, Marc-Alain Widdowson1, Eric Mintz1
MEASUREMENT OF ANTIBODY FINE SPECIFICITIES INDUCED
BY MALARIA VACCINE FMP1/AS02A FROM A PEDIATRIC
PHASE 2B TRIAL IN WESTERN KENYA
1
Centers for Disease Control and Prevention, Atlanta, GA, United States,
KEMRI/Centers for Disease Control and Prevention, Kisumu, Kenya,
3
KEMRI, Kisumu, Kenya, 4KEMRI/Centers for Disease Control and Prevention,
Nairobi, Kenya
Evelina Angov1, Elke S. Bergmann-Leitner1, Elizabeth H. Duncan1,
Afiya Brent-Kirk1, Michael McCasland1, Ryan Mease1, Lorraine S.
Soisson2, Marie-Ange Demoitié3, Bernhards Ogutu4, D. Gray
Heppner1, Jeffrey A. Lyon1
2
1
United States Agency for International Development, Washington, DC,
United States, 3GlaxoSmithKline Biologicals, Rixensart, Belgium, 4Kenya
Medical Research Institute, Kisumu, Kenya
8:15 a.m.
2
16
FACTORS ASSOCIATED WITH KWASHIORKOR IN BOTSWANA
DURING AN OUTBREAK OF DIARRHEA AND MALNUTRITION
AMONG YOUNG CHILDREN
9:15 a.m.
13
Lydia Lu1, Tracy Creek1, Ondrej Mach1, Laurel Zaks1, Japhter
Masunge2, Margarett Davis3
PURIFIED IGGS FROM UNVACCINATED MALIANS INTERFERE
WITH THE BIOLOGICAL ACTIVITY OF APICAL MEMBRANE
ANTIGEN 1-SPECIFIC IGGS AS JUDGED BY THE IN VITRO
GROWTH INHIBITION ASSAY
1
Botswana Ministry of Health, Gaborone, Botswana, 3CDC - BOTUSA,
Gaborone, Botswana
2
Kazutoyo Miura1, Hong Zhou1, Gregory Mullen1, Samuel Moretz1,
Ababacar Diouf1, David Diemert1, Alassane Dicko2, Louis Miller1,
Ogobara Doumbo2, Carole Long1
8:30 a.m.
17
1
Malaria Vaccine Development Branch, National Institute of Allergy and
Infectious Diseases, National Institutes of Health, Rockville, MD, United
States, 2Malaria Research and Training Center, Departments of Hematology
and Parasitology, University of Bamako, Bamako, Mali
FLUID MANAGEMENT AMONG CHILDREN PRESENTING TO AN
EMERGENCY DEPARTMENT DURING A DIARRHEA OUTBREAK
IN BOTSWANA
9:30 a.m.
Anna Bowen1, Wences Arvelo1, Andrea Kim1, Tracy Creek1,
Japhter Masunge2, Margarett Davis1
14
1
Nyangabgwe Hospital, Fancistown, Botswana
2
DYNAMICS OF POLYMORPHISM IN PLASMODIUM FALCIPARUM APICAL MEMBRANE ANTIGEN-1 OVER THREE YEARS
AT A VACCINE-TESTING SITE IN MALI
8:45 a.m.
18
Shannon Takala1, Amed Ouattara1, Drissa Coulibaly2, Mahamadou
A. Thera2, Alassane Dicko2, Ando B. Guindo2, Abdoulaye K. Kone2,
Karim Traore2, Abdoulaye Djimde2, Kirsten E. Lyke1, Dapa A. Diallo2,
Ogobara K. Doumbo2, Christopher V. Plowe1
SUSCEPTIBILITY TO VIBRIO CHOLERAE INFECTION IN A
COHORT OF HOUSEHOLD CONTACTS OF PATIENTS WITH
CHOLERA IN BANGLADESH
1
Jason B. Harris1, Regina LaRocque1, Fahima Chowdhurry2,
Ashraful Kahn2, Tanya Logvinenko1, Abu S. Faruque2, Edward T.
Ryan1, Firdausi Qadri2, Stephen Calderwood1
2
1
Massachusetts General Hospital, Boston, MA, United States, 2International
Center for Diarrhoeal Disease Research, B, Dhaka, Bangladesh
51
Monday, November 5
Detailed Program
www.astmh.org
9 a.m.
Symposium 13
19
Ethics of Research for Health in Developing Countries
PROSPECTIVE STUDY OF DIARRHEA DUE TO PARASITES IN
ADULT POPULATION AT A NAVAL BASE IN ANCÓN, LIMA,
PERÚ
Salon E
Paola A. Torres-Slimming1, Roger V. Araujo Castillo1, Moises
Huaman1, Carmen C. Mundaca1, Jose Quispe2, Andres G. Lescano1,
Manuel Moran2, Miguel Fernandez2, David L. Blazes1
Although the Special Programme for Tropical Diseases Research from the
World Health Organization (TDR/WHO) was created in 1975, it is quite
clear that direct benefits for the affected population have not been as
much as the products of health research. In one hand this led to change
the terminology for research for health used by TDR/WHO the present year,
207, but the main problem remains to be solved. On the other hand The
Global Forum for Health Research (GFH) in its “10/90 Report” pointed out
the injustice of spending 90% of all medical research funding on diseases
that cause 10% of the global burden of disease, which means that less
than 10% of financial resources are invested to solve neglected diseases
affecting the poor people living in developing countries. In this symposium
we review some of the most relevant ethical dilemmas faced by the stakeholders participating in research for health in developing countries.
1
Naval Medical Research Center Detachment, Lima, Peru, 2Centro Medico
Naval, Lima, Peru
9:15 a.m.
20
PREDICTORS OF NON-TYPHOIDAL SALMONELLA BACTEREMIA
IN FEBRILE CHILDREN PRESENTING AT HOSPITAL IN A
PLASMODIUM FALCIPARUM HOLOENDEMIC AREA OF WESTERN KENYA
CHAIR
Tom Were1, Gregory Davenport2, Oscar Odunga1, Collins Ouma1,
Richard Otieno1, Yamo Ouma1, John Vulule3, Alloys Orago4, Michael
Otieno4, Gordon Awandare2, Stephen Obaro2, John Michael
Ong’echa1, Douglas Perkins2
Fernando J. Andrade-Narváez
Universidad Autónoma de Yucatan, Merida, Mexico
1
Ruth Macklin
(ACMCIP Abstract)
8 a.m.
9:30 a.m.
ETHICS OF RESEARCH FOR HEALTH IN DEVELOPING
COUNTRIES: INTRODUCTION
University of Pittsburgh/KEMRI, Kisumu, Kenya, 2University of Pittsburgh,
Pittsburgh, PA, United States, 3KEMRI, Kisumu, Kenya, 4Kenyatta University,
Nairobi, Kenya
Albert Einstein College of Medicine of Yeshiva University, Bronx,
United States
21
Fernando Andrade-Narvaez
Universidad Autónoma de Yucatan, Merida, Mexico
IMPROVING MANAGEMENT OF SEVERE FEBRILE ILLNESS IN
CHILDREN: INITIAL ASSESSMENT AND DESIGN OF AN INTERVENTION IN RURAL TANZANIA
1
2
8:25 a.m.
WHAT IS OWED TO RESEARCH SUBJECTS IN DEVELOPING
COUNTRIES DURING AND AFTER CLINICAL TRIALS IN WHICH
THEY ARE PARTICIPANTS?
2
Thomas Lyimo , Nicholas Walter , Jacek Skarbinski , Emmy
Metta1, Peter McElroy3, Brenden Flannery2, Elizeus Kahigwa1, S.
Patrick Kachur2
1
Centers for Disease Control and Prevention/Ifakara Health Research and
Development Centre Malaria Programme in Tanzania, Dar-es-Salaam, United
Republic of Tanzania, 2Centers for Disease Control and Prevention, Atlanta,
GA, United States, 3Centers for Disease Control and Prevention, Dar-esSalaam, United Republic of Tanzania
Ruth Macklin
Albert Einstein College of Medicine of Yeshiva University, Bronx,
United States
8:50 a.m.
CANCER TRIALS IN DEVELOPING COUNTRIES: NEW TARGET
DRUGS AND ITS BIOETHICAL IMPLICATIONS
Emma L. Verástegui
Instituto Nacional de Cancerología, México, DF, Mexico
9:15 a.m.
ETHICS OF RESEARCH FOR HEALTH IN LEISHMANIASIS
Fernando J. Andrade-Narváez
Universidad Autónoma de Yucatán, Mérida, Mexico
Exhibit Hall Open
Franklin Hall B
Monday, November 5, 2007 9:30 a.m. - 10:30 a.m.
52
www.astmh.org
Coffee Break
11:15 a.m.
Franklin Hall B
GENETIC DIVERSITY IN PLASMODIUM FALCIPARUM
Sarah Volkman
Poster Session A Set-Up
11:25 a.m.
Franklin Hall B
APPLICATION OF GENETIC DIVERSITY TO HUMAN INFECTION
WITH PLASMODIUM FALCIPARUM
Franklin Hall B
Symposium 15
Monday, November 5, 2007 10:15 a.m. - Noon
Vectors in the Pathogenesis of Emerging Bacterial
Vector-Borne Zoonoses
Symposium 14
Salon CD
Malaria Genetic Diversity
Salon AB
This symposium is designed to introduce and review novel pathogenetic
concepts of emerging vector-transmitted bacterial anthropozoonoses. The
main emphasis of the program is to advance the understanding of fundamental disease mechanisms and how these processes are substantially influenced by events at the vector-pathogen and vector-host interface. Four
important emerging pathogens and four different acarid vector systems will
serve as platforms for conveying general principles and specific disease-related information: Ehrlichia spp., including Ehrlichia chaffeensis (Amblyomma
tick-transmitted), Anaplasma phagocytophilum (Ixodes tick-transmitted),
Francisella tularensis (Dermacentor spp. transmitted) and Orientia tsutsugamushi (Leptotrombidium spp. chigger transmitted).
This symposium will review and update the progress of the malaria genetic
diversity both from the perspective of the parasite and the human host.
Lessons from the human genome Haplotype Mapping (HapMap) Project will
be discussed as a model for how population genetic approaches can be
used to associate genetic mutations with disease. A review and discussion
of the extent of genetic diversity in the human malaria P. falciparum will be
presented, as well how this information can be utilized to understand the
biology and pathogenesis of these organisms. Finally, applications of these
findings on investigations of human infection with P. falciparum will be discussed. It is the goal of this symposium to explore how population genetic
approaches can reveal mechanisms of malaria disease and pathogenesis.
CHAIR
J. Stephen Dumler
CHAIR
The Johns Hopkins University School of Medicine, Baltimore, MD,
United States
Dyann Wirth
David H. Walker
University of Texas Medical Branch at Galveston, Galveston, TX,
United States
10:15 a.m.
INTRODUCTION
10:15 a.m.
Dyann Wirth
EHRLICHIA SPECIES AND TICKS: INFLUENCE OF TICK CELL
PROPAGATION ON PATHOGEN MOLECULAR STRUCTURE
AND INFECTIVITY
10:25 a.m.
SELECTION IN THE HUMAN GENOME AND ASSOCIATION
STUDIES IN HUMANS
Roman R. Ganta
Kansas State University, Manhattan, KS, United States
Dominic Kwiatkowski
Wellcome Trust Center for Human Genetics, Oxford, United Kingdom
10:40 a.m.
10:55 a.m.
TICK SALIVA AND THE TRANSMISSION OF BORRELIA AND
ANAPLASMA
Erol Fikrig
Matthew Berriman
Sanger Institute, Cambridge, United Kingdom
11:05 a.m.
11:05 a.m.
TULAREMIA IN DERMACENTOR: GENETIC DIVERSITY AND
DISEASE OUTBREAKS
Xinzhou Su
Sam R. Telford
National Institutes of Health, Bethesda, MD, United States
Tufts Cummings School of Veterinary Medicine, Boston, MA, United States
53
Monday, November 5
www.astmh.org
Detailed Program
11:30 a.m.
Symposium 17
REEMERGENCE OF SCRUB TYPHUS - ROLE OF THE CHIGGER
IN PATHOGENESIS
New Insights and Updates on Vivax Malaria
David H. Walker
Salon F
University of Texas Medical Branch at Galveston, Galveston, TX,
United States
Salon E
This symposium will review and update progress in understanding the biology of P. vivax malaria and its clinical implications. The clinical significance of
recent reports of genetically distinct populations of vivax clonal parasites
between primary and relapse infections will be reviewed. In addition speakers will discuss the limitations of currently available chemoprophylaxis agents
for the complete prevention of vivax malaria, the evidence base for optimal
radical cure and preventive anti-relapse therapy (PART). Finally, the performance of current generation RDTs for vivax malaria will be reviewed.
Monday, November 5, 2007 10:15 a.m. – 12:20 p.m.
CHAIR
This symposium will focus on the molecular mechanisms of intracellular or
extracellular survival of Leishmania spp and Trypanosoma spp. in the mammalian host. Talks will focus on the effect of the intracellular leishmania on
the physiology of the macrophage, the roles of glycoconjugates, lipids, and
iron acquisition in leishmania virulence, vascular changes during
Trypanosoma cruzi infection and evasion of serum lytic factors by
Trypanosoma brucei.
Eli Schwartz
CHAIR
CRITICAL EVALUATION OF CHEMOPROPHYLAXIS FOR P. VIVAX
Mary E. Wilson
Eli Schwartz
Sheba Medical Center, Tel Hashomer, Israel
10:15 a.m.
10:40 a.m.
ALTERATIONS IN MONOCYTE/MACROPHAGE PHYSIOLOGY
DURING LEISHMANIASIS
NEW INSIGHT INTO THE BIOLOGY OF P. VIVAX
David M. Mosser
Australian Army Malaria Institute, Brisbane, Australia
Symposium 16
Cell and Molecular Biology of Trypanosomatid
Infections: Host Parasite Interactions
Sheba Medical Center, Tel Hashomer, Israel
Alan Magill
10:15 a.m.
Qin Cheng
University of Maryland, College Park, MD, United States
11:05 a.m.
10:40 a.m.
HOW TO RADICALLY CURE P. VIVAX MALARIA
IRON TRANSPORT BY INTRACELLULAR LEISHMANIA AMAZONENSIS
Alan Magill
Norma Andrews
Yale University, New Haven, CT, United States
11:30 a.m.
11:05 a.m.
DIAGNOSIS OF VIVAX MALARIA WITH A FOCUS ON THE USE
OF RAPID DIAGNOSTIC TESTS (RDTS)
Scott R. Miller
THE ROLE(S) OF LEISHMANIA SURFACE GLYCOCONJUGATES
AND LIPIDS IN VIRULENCE
Stephen M. Beverley
Washington University, St. Louis, MO, United States
11:30 a.m.
Flavivirus II - Dengue II
THE VASCULOPATHY OF CHAGAS’ DISEASE
Salon G
Herbert B. Tanowitz
Albert Einstein College of Medicine, Bronx, NY, United States
CHAIR
11:55 a.m.
Irene Bosch
TRYPANOSOME LYTIC FACTOR IN HUMAN SERUM
Stephen Hajduk
Cameron Simmons
Marine Biological Laboratory, Woods Hole, MA, United States
OUCRU Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam
54
10:15 a.m.
www.astmh.org
11:30 a.m.
27
22
CHALLENGES FOR MEASURING GLOBAL DENGUE BURDEN:
OVERCOMING SEVERE LIMITATIONS OF COUNTRY PASSIVE
SURVEILLANCE SYSTEMS
DENGUE PATHOGENESIS; HOST AND VIRAL LESSONS FROM
VIETNAMESE INFANTS AND CHILDREN
Cameron Simmons, Bich Chau Tran Nguyen, Hung Nguyen Thanh,
Thi Thuy Tran, Phuong Dung Nguyen Thi, Ha Quyen Nguyen Than,
Jeremy Farrar
Jose Suaya, Donald S. Shepard
Oxford Clinical Research Unit and Hospital for Tropical Diseases, Ho Chi
Minh City, Vietnam
11:45 a.m.
28
10:30 a.m.
MULTI-COUNTRY STUDY OF COSTS OF DENGUE AMONG
AMBULATORY AND HOSPITALIZED PATIENTS
23
EVIDENCE FOR A CONSERVED T CELL RECEPTOR REPERTOIRE
IN MEMORY CD8+ T CELLS SPECIFIC FOR AN IMMUNODOMINANT CTL EPITOPE IN DENGUE 1 NS5
Jose A. Suaya1, Donald S. Shepard1, Blas Armien2, Mariana
Caram1, Leticia Castillo3, Ngan Chantha4, Fàtima Garrido5,
Sukhontha Kongsin6, Lucy Lum7, Romeo Montoya8, Binod K. Sah1,
João B. Siqueira9, Rana Sughayyar1, Karen Tyo1
Allison Imrie, Janet Meeks, Alexandra Gurary, Munkhzul
Sukhbaatar
1
Brandeis University, Waltham, MA, United States, 2Instituto Conmemorativo
Gorgas de Estudios de la Salud, Panama City, Panama, 3National Health
Laboratory, Guatemala City, Guatemala, 4The National Dengue Control
Program at the National Center for Malaria, Phnom Penh, Cambodia,
5
Ministry of Health and Social Development, Caracas, Venezuela, 6Mahidol
University, Bangkok, Thailand, 7University of Malaya Medical Center, Kuala
Lumpur, Thailand, 8Ministry of Health and Social Assistance, San Salvador, El
Salvador, 9Federal University of Goiás, Goiana, Brazil
University of Hawaii at Manoa, Honolulu, HI, United States
10:45 a.m.
24
MOLECULAR MARKERS IN SECONDARY DENGUE INFECTION:
ELEVATED SOLUBLE ST2 PROTEIN (IL-33 RECEPTOR) IN SERA
Irene Bosch1, Aniuska Becerra-Artiles1, Rajas Warke1, Norma de
Bosch2, Alan Rothman1
Symposium 19
1
University of Massachusetts Medical School, Worcester, MA, United States,
Banco de Sangre, Caracas, Venezuela
Scaling Up ACTs - The Challenge of Monitoring and
Ensuring Safety, and Developing an Effective
Surveillance System in Malaria Endemic Regions
2
11 a.m.
25
Salon H
SIGNIFICANT INCREASE IN DENGUE SEVERITY BETWEEN 2005
AND 2006 IN A HOSPITAL-BASED STUDY IN NICARAGUA
As Artemisinin-based Combination Therapies begin to be widely used in
malaria endemic countries, the public health community is faced with a formidable challenge of monitoring their safety. As these new drugs have only
been carefully trialed in controlled settings in less than a few thousands
patients for each drug, only an effective surveillance system will be able to
pick up rare and serious adverse events. ACTs are currently not recommended for pregnant women in their first trimester, what are the data in embryo
toxicity and what are their implications? How can a pregnancy exposure
registry assist in monitoring the safety of ACTs? The session will also look at
what types of surveillance systems are in place to monitor drug safety and
which types of additional systems could be considered that are appropriate
and feasible in developing countries.
Crisanta Rocha1, Sheyla Silva1, Andrea Nuñez2, Aubree Gordon3,
Douglas Elizondo2, Yolanda Tellez2, Tangni Gomez2, Niall Lennon4,
Matthew Henn4, Angel Balmaseda2, Eva Harris3
1
Hospital Infantil Manuel de Jesus Rivera, Managua, Nicaragua,
Departamento de Virologia, Centro Nacional de Diagnostico y Referencia,
Ministerio de Salud, Managua, Nicaragua, 3Division of Infectious Diseases,
School of Public Health, University of California, Berkeley, Berkeley, CA,
United States, 4Broad Institute, Cambridge, MA, United States
2
11:15 a.m.
26
CHAIR
ESTIMATING THE INCIDENCE OF DENGUE FEVER IN
CAMBODIA: RESULTS OF A CAPTURE RECAPTURE ANALYSIS
Charles Mgone
European and Developing Countries Clinical Trials, The Hague, The
Netherlands
Sirenda Vong1, Chantha Ngan2, Philippe Buchy1, Virak Khieu1,
Rekol Huy2, Veasna Duong1, Sivuth Ong1, Socheat Duong2, Moh
Seng Chang3, Zhi-yi Xu4, Harold S. Margolis5
10:15 a.m.
1
Institut Pasteur - Cambodia, Phnom Penh, Cambodia, 2National Dengue
Control Program - Ministry of Health, Phnom Penh, Cambodia, 3World
Health Organization - Phnom Penh Office, Phnom Penh, Cambodia,
4
International Vaccine Institute, Seoul, Republic of Korea, 5Pediatric Dengue
Vaccine Initiative - International Vaccine Institute, Seoul, Republic of Korea
EMBRYOTOXICITY OF ARTEMISININS - USING PRECLINICAL
DATA TO ASSESS POTENTIAL CONSEQUENCES FOR HUMAN USE
Robert Clark
Independent Consultant, Philadelphia, PA, United States
55
Monday, November 5
Heller School, Brandeis Uiversity, Waltham, MA, United States
www.astmh.org
Detailed Program
10:40 a.m.
10:45 a.m.
MONITORING THE SAFETY OF ACTS IN PREGNANCY - USE OF
PREGNANCY EXPOSURE REGISTRIES
ONGOING EPIDEMIOLOGICAL STUDIES OF S. JAPONICUM
TRANSMISSION IN CHINA INCLUDING TRANSMISSION BLOCKING VACCINE STUDIES
Feiko O. ter Kuile
Child and Reproductive Health, Liverpool School of Tropical Medicine,
Liverpool, United Kingdom
Donald P. McManus
11:05 a.m.
11:10 a.m.
ACTS IN ENDEMIC COUNTRY?
Alex Dodoo
TRANSMISSION OF S. JAPONICUM WITHIN AND BETWEEN
NEARBY VILLAGES IN CHINA
University of Ghana Medical School, Accra, Ghana
Robert C. Spear
University of California, Berkeley, CA, United States
11:30 a.m.
11:35 a.m.
PROSPECTIVE FOR MONITORING NEW ACTS IN RURAL
SETTINGS - OPTIMIZING THE USE OF DEMOGRAPHIC
SURVEILLANCE SYSTEMS
A GENETIC COMPARISON OF S. JAPONICUM RECOVERED
FROM MAMMALIAN HOSTS IN THE PHILIPPINES AND CHINA
Fred Binka
Joanne P. Webster
University of Ghana, Accra, Ghana
Symposium 20
The Transmission and Control of Schistosoma Japonicum
Intestinal and Tissue Helminths I: Cestodes
Salon IJ
Salon KL
Monday, November 5, 2007
10:15 a.m. - Noon
Approximately 1.5 million people are infected with Schistosoma japonicum
in China and the Philippines. Although the life-cycle was accurately
described nearly 100 years ago, the relative importance to human disease of
the different parts of the life-cycle are not known, e.g. the concentration
and infection status of different parasite stages and the number and infection status of non-human mammalian hosts. Ongoing ecological field studies in China and the Philippines have been designed to obtain quantitative
and genetic evidence with which to reduce these uncertainties. The following are examples of specific questions likely to be addressed during the symposium: How much human infection would be averted by the widespread
use of an effective bovine vaccine in the different countries? Do strains of S.
japonicum preferentially infect different mammalian hosts? Can data on
topology and rainfall be used to predict local between village infection
dynamics?
CHAIR
Hector H. Garcia
Universidad Peruana Cayetano Heredia, Lima, Peru
A. Clinton White
10:15 a.m.
29
EFFICACY OF OXFENDAZOLE, ALBENDAZOLE AND PRAZIQUANTEL AGAINST CYSTIC ECHINOCOCCOSIS IN NATURALLY
INFECTED SHEEP
CHAIR
Cesar M. Gavidia1, Armando E. Gonzalez1, Monica Llamosas1,
Eduardo A. Barron1, Hector H. Garcia2, Manuela R. Verastegui3,
Robert H. Gilman4
Steven Riley
The University of Hong Kong, Hong Kong
1
Universidad Nacional Mayor de San Marcos, Facultad de Medicina
Veterinaria, Lima, Peru, 2Instituto de Ciencias Neurologicas, Lima, Peru,
3
Universidad Peruana Cayetano Heredia, Lima, Peru, 4The Johns Hopkins
University, Bloomberg School of Public Health, Baltimore, MD, United States
10:15 a.m.
INTRODUCTION
Steven Riley
The University of Hong Kong, Hong Kong
10:25 a.m.
TRANSMISSION OF S. JAPONICUM IN 50 VILLAGES IN THE
PHILIPPINES
Stephen T. McGarvey
56
10:30 a.m.
www.astmh.org
11:15 a.m.
30
33
CLUSTERS OF CONFIRMED SWINE CYSTICERCOSIS INFECTION
SURROUNDING TAENIA SOLIUM TAPEWORM CARRIERS
ANTIGEN-DETECTION IN NEUROCYSTICERCOSIS: SENSITIVITY
AND SPECIFICITY ACCORDING TO PARASITE STAGE AND
NUMBER OF LESIONS
Andres G. Lescano1, Armando E. Gonzalez2, Robert H. Gilman3,
Victor C.W. Tsang4, C. Sofia Arriola3, Daphne D. Ramos2, André
Díaz2, Viterbo Aybar2, Silvia Rodriguez5, Lawrence H. Moulton3, Elli
Leontsini3, Guillermo Gonzalvez6, Hector H. Garcia6, for the
Cysticercosis Working Group in Peru6
Yesenia Castillo1, Dorny Pierre2, Patricia Arias1, Milagrytos
Portocarrero1, Silvia Rodriguez3, Bjorn Victor2, Kirezi kanobana2,
Robert Gilman4, Gonzalez Armando5, Jef Brandt2, Hector Garcia1
UPCH, Department of Microbiology, Lima, Peru, 2Institute for Tropical
Medicine, Antwerp, Belgium, 3Instituto de Ciencias Neurologicas, Lima,
Peru, 4Department of International Health, Johns Hopkins School of Public
Health, Baltimore, MD, United States, 5Universidad Mayor de San Marcos,
School of veterinary Medicine, Lima, Peru
US Naval Medical Research Center Detachment, Lima, Peru, 2Universidad
Nacional Mayor de San Marcos, Facultad de Medicina Veterinaria, Lima,
Peru, 3Johns Hopkins Bloomberg School of Public Health, Baltimore, MD,
United States, 4Centers for Disease Control and Prevention, Atlanta, GA,
United States, 5Instituto de Ciencias Neurológicas, Unidad de Cisticercosis,
Lima, Peru, 6Universidad Peruana Cayetano Heredia, Departamento de
Microbiología, Facultad de Ciencias, Lima, Peru
(ACMCIP Abstract)
11:30 a.m.
34
10:45 a.m.
31
COMPOSITION AND RELEASE PATTERN OF PARASITE
GLYCOCONJUGATES DURING THE COURSE OF HUMAN AND
EXPERIMENTAL NEUROCYSTICERCOSIS
EFFICACY OF NICLOSAMIDE GIVEN AS MASS OR TARGETED
TREATMENT FOR T. SOLIUM TAENIASIS
Jorge I. Alvarez, Judy M. Teale
Juan Jimenez1, Silvia Rodriguez2, Luz Maria Moyano3, Guillermo
Gonzalvez3, Carmen Taquri3, Luis Piscoya3, Robert Gilman4,
Armando Gonzales5, Victor Tsang6, Hector Garcia7, for The
Cysticercosis Working Group in Peru8
UTSA, San Antonio, TX, United States
(ACMCIP Abstract)
11:45 a.m.
1
School of Veterinary Medicine, Universidad Nacional Mayor de San Marcos,
Lima, Peru, 2Department of Microbiology (SR, CT, HG) and Cysticercosis
Elimination Project (Tumbes) (LM, GG, LP), Universidad Peruana Cayetano
Heredia, Lima, Peru, Cysticercosis Unit, Instituto de Ciencias Neurologicas,
Lima, Peru, 3Department of Microbiology (SR, CT, HG) and Cysticercosis
Elimination Project (Tumbes) (LM, GG, LP), Universidad Peruana Cayetano
Heredia, Lima, Peru, 4Department of International Health, Johns Hopkins
Bloomberg School of Public Health, Baltimore, MD, United States, 5School
of Veterinary Medicine, Universidad Nacional Mayor de San Marcos, Lima,
Peru. Department of International Health, Johns Hopkins Bloomberg School
of Public Health, Baltimore, MD, United States, 6Centers for Disease Control
and Prevention, Atlanta, GA, United States, 7Department of Microbiology
(SR, CT, HG) and Cysticercosis Elimination Project (Tumbes) (LM, GG, LP),
Universidad Peruana Cayetano Heredia, Lima, Peru, Department of
International Health, Johns Hopkins Bloomberg School of Public Health,
Baltimore, MD, United States, 8Universidad Peruana Cayetano Heredia,
Lima, Peru
35
IDENTIFICATION OF A 38 KDA SPECIFIC ANTIGEN FOR THE
DIAGNOSIS OF COENUROSIS
Natalia Rojas1, Saul J. Santivañez1, Silvia Rodriguez2, Mary L.
Rodriguez1, Carmen Calderon1, Manuelita Verastegui1, Armando E.
Gonzales3, Hector H. Garcia2
1
UPCH, Department of Microbiology, School of Sciences, Lima, Perú, 2IECN,
Lima, Peru, 3Universidad Nacional Mayor de San Marcos, School of
Veterinary Medicine, Lima, Peru
(ACMCIP Abstract)
Malaria - Vector Biology and Transmission
11 a.m.
Liberty AB
32
CONTEMPORARY NEUROSURGICAL APPROACHES TO
NEUROCYSTICERCOSIS
CHAIR
Leonardo Rangel-Castilla1, Jose A. Serpa2, Shankar P. Gopinath2,
Edward A. Graviss2, A. Clinton White1
National Institutes of Health, Rockville, MD, United States
Carolina Barillas-Mury
Jerome Vanderberg
1
University of Texas Medical Branch, Galveston, TX, United States, 2Baylor
College of Medicine, Houston, TX, United States
New York University School of Medicine, New York, NY, United States
57
Monday, November 5
1
1
Detailed Program
www.astmh.org
10:15 a.m.
11:30 a.m.
36
41
DEVELOPMENTAL ARREST OF MALARIA PARASITES IN MOSQUITOES FOLLOWING TREATMENT OF MICE WITH AS-I-145
SAMPLING TOOLS FOR ADULT MALARIA VECTORS IN URBAN
DAR ES SALAAM, TANZANIA
Lisa A. Purcell1, Stephanie K. Yanow1, Gabriele Pradel2, Ana
Rodriguez3, Moses Lee4, Terry W. Spithill1
Nicodem Govella1, Yvonne Geissbühler2, Prosper Chaki1, Japhet
Kihonda1, Robert Anderson3, Khadija Kannady4, Deo Mtasiwa5,
Marcel Tanner2, Ulrike Fillinger1, Ulrike Fillinger6, Steven Lindsay6,
Gerry Killeen1
1
McGill University, Institute of Parasitology and Centre for Host-Parasite
Interactions, Sainte-Anne-de-Bellevue, QC, Canada, 2University of Würzburg,
Research Center for Infectious Diseases, Würzburg, Germany, 3Department
of Medical Parasitology, New York University School of Medicine, New York,
NY, United States, 4Hope College, Division of Natural and Applied Sciences
and Department of Chemistry, Holland, MI, United States
1
Ifakara Health Research and Development Centre, Dar es Salaam, United
Republic of Tanzania, 2Swiss Tropical Institute, Basel, Switzerland, 3Ifakara
Health Research and Development Centre, Dar es Salaam, United Republic
of Tanzania, 4Dar es Salaam Urban Malaria Control Programme, Dar es
Salaam, United Republic of Tanzania, 5Dar es Salaam City Council, Dar es
Salaam, United Republic of Tanzania, 6Durham University, Durham, United
Kingdom
10:30 a.m.
37
11:45 a.m.
DIRECT MICROSCOPIC QUANTIFICATION OF TRANSMISSION
DYNAMICS OF PLASMODIUM SPOROZOITES FROM
MOSQUITOES TO MICE
42
HEROIC FAILURES? THE FIRST SOUTH ASIAN MALARIA
CONTROL PROJECTS AFTER THE DISCOVERY OF MOSQUITO
TRANSMISSION
Chahnaz Kebaier, Yamei Jin, Jerome Vanderberg
G. Dennis Shanks1, David J. Bradley2
10:45 a.m.
1
Australian Army Malaria Institute, Brisbane, Australia, 2Department of
Zoology, University of Oxford, Oxford, United Kingdom
38
PLASMODIUM FALCIPARUM GENETIC STRUCTURE IN THE
FOUR MAJOR AFRICAN ANOPHELES VECTORS
Zeinab Annan1, Patrick Durand1, Parfait Awono-Ambene2, Frédéric
Simard2, Céline Arnathau1, François Renaud1, Didier Fontenille3
Malaria - Vaccines II
Liberty C
1
Centre National de la Recherche Scientifique/Institut de Recherche pour le
Développement, Montpellier, France, 2Institut de Recherche pour le
Développement, Organisation de lutte Contre les Endémies en Afrique
Centrale, Yaoundé, Cameroon, 3Institut de Recherche pour le
Développement, Montpellier, France
CHAIR
Myriam Arevalo-Herrera
Malaria Vaccine and Drug Development Center, Cali, Colombia
11 a.m.
Takafumi Tsuboi
39
Ehime University, Matsuyama, Ehime, Japan
ANOPHELES GAMBIAE STAT PATHWAY PARTICIPATES IN MOSQUITO IMMUNITY
10:15 a.m.
43
Lalita Gupta, Sanjeev Kumar, Carolina Barillas-Mury
REPRODUCIBILITY OF A SPOROZOITE CHALLENGE MODEL FOR
PLASMODIUM VIVAX IN HUMAN VOLUNTEERS
11:15 a.m.
Johanna A. Parra1, Leonardo Rocha2, Ricardo Palacios3, Juan
Diego Velez4, Judith Epstein5, Tom Richie5, Myriam Arevalo-Herrera1,
Socrates Herrera1
40
PRESENCE OF MALARIA ASEXUAL BLOOD STAGES SIGNIFICANTLY DECREASES THE BURDEN OF P. FALCIPARUM
OOCYSTS IN ANOPHELES MOSQUITOES AFTER MEMBRANE
FEEDING ASSAYS
1
Malaria Vaccine and Drug Testing Center, Cali, Colombia, 2Immunology
Institute, Cali, Colombia, 3Praca Marisa Marques-University Sao Pablo, Brazil,
4
Fundación Clínica Valle de Lili, Cali, Colombia, 5Malaria Program, Naval
Medical Research Center, Silver Spring, MD, United States
Yessika Vasquez1, Luke A. Baton2, George Dimopoulos2,
Nirbhay Kumar2
1
Johns Hopkins Malaria Research Institute Parasite Core, Bloomberg School
of Public Health, Baltimore, MD, United States, 2Johns Hopkins School of
Public Health, Baltimore, MD, United States
(ACMCIP Abstract)
58
10:30 a.m.
www.astmh.org
44
COMPARISON OF THE IMMUNOGENICITY OF ADENOVIRUS
35-PFCS ALONE AND IN HETEROLOGOUS COMBINATION
WITH AN ADENOVIRUS 5-PFCS CONSTRUCT
1
Naval Medical Research Center, Silver Spring, MD, United States, 2GenVec,
Inc., Gaithersburg, MD, United States, 3Laboratory of Malaria and Vector
Research, National Institute of Allergy and Infectious Diseases/National
Institutes of Health, Rockville, MD, United States, 4PATH Malaria Vaccine
Initiative, Bethesda, MD, United States, 5United States Agency for
International Development, Malaria Vaccine Development Program,
Washington, DC, United States
V. Ann Stewart1, Shannon M. McGrath1, Maria Grazia Pau2, Pascal
Mettens3, Patrice M. Dubois4, Joseph Shott1, Maria-Ange Demoitie3,
Jerome HHV Custers2, Gerrit-Jan Weverling2, Babak Bayat3, MarieNoelle Donner3, Marie-Claude Dubois3, Joe Cohen3, Jaap
Goudsmit2, D. Gray Heppner1
1
Crucell Holland BV, Leiden, The Netherlands, 3GlaxoSmithKline Biologicals,
Rixensart, Belgium, 4ImmunoVacc Consulting, Brussels, Belgium
2
11:45 a.m.
49
10:45 a.m.
INDUCTION OF ANTIBODIES IN RABBITS AGAINST THE PREGNANCY MALARIA VACCINE CANDIDATE VAR2CSA USING
PICHIA PASTORIS YEAST AND PLASMID DNA IMMUNIZATION
45
A NON-ADJUVANTED SELF-ASSEMBLING POLYPEPTIDE
NANOPARTICLE (SAPN) MALARIA VACCINE CONFERS STERILE
PROTECTION TO LETHAL SPOROZOITE CHALLENGE
Marion Avril1, Bridget Kulasekara1, Severin Gose1, Chris Rowe2,
Madeleine Dahlbäck3, Ali Salanti3, Lynda Misher1, David L. Narum2,
Joe D. Smith1
Stephen A. Kaba1, Clara Brando1, David Tropel2, Peter Burkhard3,
David Lanar1
1
Seattle Biomedical Research Institute, Seattle, WA, United States,
MVDB/National Institute of Allergy and Infectious Diseases/National
Institutes of Health, Rockville, MD, United States, 3Center for Medical
Parasitology, Copenhagen, Denmark
2
1
M.E. Mueller Institute for Structural Biology, Basel, Switzerland, 3Alpha-O
Peptides AG, Allschwil, Switzerland
2
Noon
11 a.m.
572
46
ENHANCED IMMUNOGENICITY OF MALARIA CS PEPTIDE VACCINES USING A TOPICAL ADJUVANT CONTAINING A POTENT
SYNTHETIC TLR LIGAND, IMIQUIMOD
A PHASE I/IIB RANDOMIZED, DOUBLE-BLIND, CONTROLLED
CLINICAL TRIAL OF THE SAFETY, IMMUNOGENICITY AND
EFFICACY OF RTS,S/AS02D, A CANDIDATE MALARIA VACCINE
IN MOZAMBICAN INFANTS
Dean Johnston1, Caroline Othoro2, Rebecca Lee2, Jean-Claude
Bystryn3, Elizabeth Nardin2
Symposium 24
1
Hunter College School of Health Sciences, New York, NY, United States,
2
Department of Parasitology, School of Medicine, New York University,
New York, NY, United States, 3Department of Dermatology and New York
University Cancer Institute, School of Medicine, New York University,
New York, NY, United States
Genomics and Functional Genomics of Filarial Parasites
Franklin 1
11:15 a.m.
The Filarial Genome Project has been recently completed and an extensive
analysis of the genome sequence has been prepared for publication. In
addition to genomics, there are exciting areas of functional genomics that
are being targeted by the filarial research community. These include microarrays, RNA interference, transgenesis and the study of the Wolbachia
endosymbiont. Such new avenues of research will enable the identification
of new drug targets and vaccine candidates that may prove useful in the
Global Programme to Eliminate Lymphatic Filariasis.
47
ANIMAL IMMUNOGENICITY STUDIES OF A BLOOD-STAGE
MALARIA VACCINE BASED ON A COMBINATION OF AMA1
AND MSP142
Laura B. Martin, Carole A. Long, Hong Zhou, Sarimar Medina,
Joseph Newland, Samuel E. Moretz, Lynn E. Lambert, Gregory E.
Mullen, Allan Saul, Louis H. Miller
CHAIR
Malaria Vaccine Development Branch, National Institute of Allergy
and Infectious Diseases/National Institutes of Health, Rockville, MD,
United States
Steven A. Williams
11:30 a.m.
Elodie Ghedin
Smith College and Task Force for Child Survival and Development,
Northampton, MA, United States
University of Pittsburgh School of Medicine, Pittsburgh, PA, United States
48
MONOVALENT AND BIVALENT ADENOVECTORED VACCINES
EXPRESSING THE PLASMODIUM FALCIPARUM ANTIGENS
AMA-1 AND MSP1-42 (3D7) ELICIT FUNCTIONAL ANTIBODIES
IN NZW RABBITS
Noelle B. Patterson1, Joseph T. Bruder2, Keith Limbach1, Andrew
59
Monday, November 5
McGrath2, Bill Enright2, C. Richter King2, Bryan T. Butman2, Kalpana
Gowda1, Ping Chen2, Svetlana Konovalova2, Samuel E. Moretz3,
Hong Zhou3, Ababacar Diouf3, Thomas L. Richie1, Sheng Li4,
Lorraine Soisson5, Carter Diggs5, Emily Locke4, Walter Brandt4,
Carole A. Long3, Denise L. Doolan1
www.astmh.org
Detailed Program
10:15 a.m.
10:45 a.m.
52
TRANSIENT TRANSFECTION TO STUDY TRANSCRIPTION IN
FILARIA
RECONTAMINATION OF HOUSEHOLD DRINKING WATER: A
CONTROLLED EXPERIMENT IN NORTHERN COASTAL ECUADOR
Thomas R. Unnasch
Karen Levy1, Kara Nelson1, Alan Hubbard1, Joseph Eisenberg2
1
University of California Berkeley, Berkeley, CA, United States, 2University of
Michigan, Ann Arbor, MI, United States
10:40 a.m.
BRUGIA MALAYI: THE GENOME AND BEYOND
11 a.m.
Elodie Ghedin
University of Pittsburgh School of Medicine, Pittsburgh, PA, United States
53
11:05 a.m.
THE WOLBACHIA ENDOSYMBIONT AS A POTENTIAL FILARIASIS DRUG TARGET
HOUSEHOLD-SCALE DRINKING WATER TREATMENT IN
CAMBODIA: A RANDOMIZED, CONTROLLED TRIAL OF LOCALLY MADE CERAMIC FILTERS
Barton Slatko
Joe Brown, Mark D. Sobsey
New England Biolabs, Ipswich, MA, United States
University of North Carolina School of Public Health, Chapel Hill, NC,
United States
11:30 a.m.
11:15 a.m.
MICROARRAYS IN STUDYING THE BIOLOGY OF FILARIAL PARASITES
54
HEALTH IMPACT STUDY OF THE BIOSAND FILTER IN BONAO,
DOMINICAN REPUBLIC
Steven A. Williams
Smith College and the Task Force for Child Survival and Development,
Northampton, MA, United States
Christine E. Stauber, Gloria M. Ortiz, Mark D. Sobsey
University of North Carolina - Chapel Hill, Chapel Hill, NC, United States
11:30 a.m.
55
Bacteriology II - Water and Water Treatment
Franklin 2
A LONG-LIFE, POINT-OF-USE HOUSEHOLD DRINKING WATER
PURIFICATION DEVICE BASED ON HALOGEN CHARGING OF
POLYSTYRENEHYDANTOIN BEADS (HALOPURE)
CHAIR
Stephen Himley, Mickey Bridges, Jeffrey F. Williams, Hiroyuki
Kawai, Jose Santiago, Nevada Ruehlen, Nicole VanKirk
Karen Levy
University of California at Berkeley, Berkeley, CA, United States
HaloSource, Inc., Bothell, WA, United States
Mark Sobsey
11:45 a.m.
University of North Carolina, Chapel Hill, NC, United States
56
10:15 a.m.
EFFICACY OF ONE DROP POINT-OF-USE CHEMICAL
DISINFECTANT TO INACTIVATE WATERBORNE
MICROORGANISMS
50
SURVIVAL OF FRANCISELLA TULARENSIS TYPE A IN
BRACKISH WATER
Jennifer L. Murphy, Ashley F. Hiser, Mark D. Sobsey
Zenda L. Berrada, Sam R. Telford
University of North Carolina at Chapel Hill, Chapel Hill, NC, United States
Tufts Cummings School of Veterinary Medicine, North Grafton, MA, United
States
Symposium 26
10:30 a.m.
Obligations to Participants in Research Trials in
Developing Countries
51
DRIVERS OF VARIABILITY IN WATER QUALITY AND
DIARRHEAL DISEASE IN NORTHERN COASTAL ECUADOR
Franklin 3/4
Karen Levy1, Alan Hubbard2, Kara Nelson2, Joseph Eisenberg3
It is commonly recognized that medical research brings with it special obligations to the subjects of research, especially where that research may be a
major source of their medical care. As the extent of research in the developing world has increased, therefore, the question of what is owed to the participants in medical trials, both during and after the trials, has become particularly pressing. Various organizations, including the Council for
1
Stanford University, Stanford, CA, United States, 2University of California
Berkeley, Berkeley, CA, United States, 3University of Michigan, Ann Arbor,
MI, United States
60
www.astmh.org
Arthropods/Entomology - Other
International Organizations of Medical Sciences (CIOMS), have issued guidelines about researchers’ obligations. But the best test of the usefulness of
such documents is how well they meet the requirements of morality when
actually applied. Consequently, this symposium will provide a critical examination of some key ethics guidelines by looking at their application to cases.
We will draw on the experience of government-sponsored researchers and
public-private partnerships who are working on major health problems of
communities in the developing world, such as Malaria and HIV/AIDS.
57
THE INSIGHTS OF MANAGING INSECTICIDE RESISTANCE IN
MALARIA VECTORS WITH THE PLANT EXTRACTS IN TROPICAL
AFRICA
Eliningaya J. Kweka1, Aneth M. Mahande2, Emmanuel A. Temu3
Republic of Tanzania, 2Joint Malaria Programme, Moshi, United Republic of
Tanzania, 3Nagasaki University Japan, Nagasaki, Japan
Joseph Millum
(ACMCIP Abstract)
10:15 a.m.
58
ADDRESSING STANDARDS OF CARE IN THE CONTEXT OF
MULTI-CENTER TRIALS
CLIMATE CHANGE AND VECTOR BORNE DISEASE IN THE
UNITED STATES: QUO VADIS
Tonya L. Villafana
Lars Eisen1, Rebecca J. Eisen2
Malaria Vaccine Initiative, Bethesda, MD, United States
1
Colorado State University, Fort Collins, CO, United States, 2Division of
Vector-Borne Infectious Diseases, Centers for Disease Control and
Prevention, Fort Collins, CO, United States
10:45 a.m.
ADDRESSING ETHICAL CONSIDERATIONS IN UNDERTAKING
MALARIA FIELD STUDIES IN DEVELOPING COUNTRIES
59
Isabela Ribeiro
Drugs for Neglected Diseases Initiative, Geneva, Switzerland
TICK BITE PREVENTION BEHAVIOR AMONG PARTICIPANTS IN
THE GEORGIA TICK ATTACH STUDY
11:10 a.m.
Laurel E. Garrison1, Dana Cole1, Marianne Vello1, Michael J.
Yabsley2, Mason Y. Savage3, Gaylord Lopez4
1
Georgia Department of Human Resources, Division of Public Health,
Atlanta, GA, United States, 2Southeastern Cooperative Wildlife Disease
Study, College of Veterinary Medicine, and Warnell School of Forestry and
Natural Resources, The University of Georgia, Athens, GA, United States,
3
Southeastern Cooperative Wildlife Disease Study, College of Veterinary
Medicine, The University of Georgia, Athens, GA, United States, 4Georgia
Poison Center, Atlanta, GA, United States
THE NIH GUIDANCE FOR ADDRESSING THE PROVISION OF
ANTIRETROVIRAL TREATMENT FOR TRIAL PARTICIPANTS
Seema Shah
11:35 a.m.
ETHICAL THEORY AND ETHICAL PRACTICE
60
Joseph Millum
COMPARISON OF IRRITANT EFFECTS OF DDT AND ALPHACYPERMETHRIN AGAINST RESISTANT AND SUSCEPTIBLE
STRAINS OF AEDES AEGYPTI (DIPTERA: CULICIDAE)
Clinical Group Education Curriculum
Committee Meeting
Isabelle C. Dusfour, John P. Grieco, Nicole L. Achee,
Donald R. Roberts
United States
Room 336
Monday, November 5, 2007 12:15 p.m. - 1:15 p.m.
61
Certificate Exam Executive Committee
Meeting
EVALUATION OF THE FAT-TAILED JIRD, PACHYUROMYS
DUPRASI NATRONENSIS (RODENTIA: GERBILLIDAE), AS A NEW
ANIMAL MODEL FOR STUDIES OF LEISHMANIA TROPICA
INFECTION AND TRANSMISSION
Room 362
Hanafi A. Hanafi1, Daniel E. Szumlas2, Shabaan S. El-Hossary1,
Jeffrey T. Villinski1, Noha Watany1, El-Shaimaa M. Nour El-Din1,
Magda M. Abbassy1, Yusuf Özbel3, David F. Hoel1, David Fryauff4
Exhibit Hall Open/Box Lunches
Poster Session A (#57 – 299)
1
U.S. Naval Medical Research Unit Number Three, Cairo, Egypt, 2Navy
Entomology Center of Excellence, Jacksonville, FL, United States,
3
Department of Parasitology, Medical School, Ege Univeristy, Izmir,Turkey,
4
Infectious Disease Directorate, U.S. Naval Medical Research Center, Silver
Spring, MD, United States
Franklin Hall B
(ACMCIP Abstract)
Franklin Hall B
Monday, November 5, 2007 Noon - 1:30 p.m.
Monday, November 5, 2007 Noon - 1:30 PM
61
Monday, November 5
1
CHAIR
Detailed Program
www.astmh.org
62
67
MOLECULAR CLONING AND CHARACTERIZATION OF A NOVEL
SPHINGOMYELINASE-LIKE PROTEIN FROM THE TICK IXODES
SCAPULARIS
MICROGEOGRAPHICAL ANALYSIS OF GENETIC STRUCTURE IN
TRIATOMA INFESTANS POPULATIONS FROM NORTHERN
ARGENTINA
Francisco J. Alarcon-Chaidez, Venkata D. Boppana, Jianxin Sun,
Adam J. Adler, Stephen K. Wikel
Paula L. Marcet1, Ana Paula Cutrera2, LeeAnn Jones3, Ricardo E.
Gürtler4, Uriel Kitron5, Ellen M. Dotson3
University of Connecticut Health Center, Farmington, CT, United States
1
Lab. Eco-Epidemiología, University Buenos Aires-Centers for Disease Control
and Prevention-Entomology Branch, Chamblee, GA, United States, 2Lab.
Ecofisiología-FCEN-University Nacional de Mar del Plata, Mar del Plata,
Argentina, 3Centers for Disease Control and Prevention-Entomology Branch,
Chamblee, GA, United States, 4Lab. Eco-Epidemiología, University Buenos
Aires, Buenos Aires, Argentina, 5University of Illinois- College of Veterinary
Medicine, Urbana, IL, United States
63
ANALYSIS OF IN SILICO STEREOELECTRONIC PROPERTIES
OF PMD (P-MENTHANE-3-8-DIOLS) AND ITS DERIVATIVES
TO DEVELOP A PHARMACOPHORE FOR INSECT
REPELLENT ACTIVITY
68
Apurba K. Bhattacharjee1, Kamalesh R. Chauhan2,
Nagendrababu Bathini2, John Greico3, Nicole Achee3, Kendra
Lawrence4, John Paul Benante4, Raj K. Gupta5
FAST-GAS: A FIELD-DEPLOYABLE SOURCE OF CARBON
DIOXIDE FOR USE IN VECTOR SURVEILLANCE
1
Division of Experimental Therapeutics, Walter Reed Army Institute of
Research, Silver Spring, MD, United States, 2United States Department of
Agriculture, Agriculture Research Center Chemicals Affecting Insect Behavior
Laboratory, Beltsville, MD, United States, 3Department of Preventive
Medicine and Biometrics, Uniformed Services University of the Health
Sciences, Bethesda, MD, United States, 4Division of Entomology, Walter
Reed Army Institute of Research, Silver Spring, MD, United States, 5Office of
the Science Director, Walter Reed Army Institute of Research, Silver Spring,
MD, United States
Philipp Kirsch1, Francis X. Webster2, Darek Czokajlo1, Christopher
V. Sack1, John R. McLaughlin1
1
APTIV Inc., Portland, OR, United States, 2State University of New York Environmental Science and Forestry, Syracuse, NY, United States
69
EVALUATION OF EARLY INFLAMMATORY RESPONSE
EXPRESSION IN RESPONSE TO PHLEBOTOMUS DUBOSCQI
BITES
64
Clarissa R. Teixeira, Shaden Kamhawi, Regis B. Gomes, Luiz F.
Oliveira, Dia-eldin Elnaiem, Jesus G. Valenzuela
DIFFERENTIAL EXPRESSION OF SALIVARY GLAND CDNAS IN
LABORATORY AND FIELD POPULATIONS OF PHLEBOTOMUS
PAPATASI
National Institute of Allergy and Infectious Disease, National Institutes of
Health, Rockville, MD, United States
Marcelo Ramalho-Ortigao1, Iliano V. Coutinho-Abreu1,
Gwen Stayback1, Mariha Wadsworth1, Emad Fawaz2,
Shaaban El-Hossary2, Hanafi Hanafi2, David Hoel2,
Mahmoud Abo-Shehada3, Jesus Valenzuela4, Shaden Kamhawi4,
Rami Mukbel1, Mary Ann McDowell1
(ACMCIP Abstract)
Cestodes - Cysticercosis
70
1
University of Notre Dame, Notre Dame, IN, United States, 2Naval Medical
Research Unit #3, Cairo, Egypt, 3Jordan University of Science and
Technology, Irbid, Jordan, 4National Institutes of Health, Rockville, MD,
United States
SERO-PREVALENCE OF CYSTICERCOSIS IN CHILDREN,
ADOLESCENTS AND ADULTS LIVING IN A SCHISTOSOMIASIS
ENDEMIC COMMUNITY IN LEYTE, THE PHILIPPINES
Jin-Mei Xu1, Luz P. Acosta2, Min Hou1, Daria L. Manalo2, Mario
Jiz2, Blanca Jarilla2, Archie O. Pablo2, Remigio M. Ovleda2, Gretchen
Langdon3, Jennifer Friedman3, Stephen T. McGarvey4, Jonathan
Kurtis3, Hai-Wei Wu1
65
OVERVIEW OF DEPLOYED WARFIGHTER PROTECTION
PROGRAM ACTIVITIES AT THE USDAS CENTER FOR MEDICAL,
AGRICULTURAL AND VETERINARY ENTOMOLOGY
1
Nanjing Medical University, Nanjing, Jiangsu, China, 2Department of
Immunology, Research Institute for Tropical Medicine, Department of Health,
Manila, Philippines, 3Center for International Health Research, Rhode Island
Hospital, Providence, RI, United States, 4International Health Institute, Brown
University School of Medicine, Providence, RI, United States
Gary G. Clark, Kenneth J. Linthicum
Agricultural Research Service, US Department of Agriculture, Gainesville, FL,
United States
66
THE EFFECT OF WEST NILE VIRUS PERCEPTIONS AND
KNOWLEDGE ON HUMAN PREVENTION PRACTICES AND
VECTOR BREEDING IN RESIDENTIAL YARDS IN UPSTATE NEW
YORK
Wieteke Tuiten, Constantianus J. Koenraadt, Katherine McComas,
Laura C. Harrington
62
www.astmh.org
Cestodes – Echinococcosis/Hytatid
71
76
CHILDREN SEROLOGY OF ECHINOCOCCOSIS INFECTION AS AN
ENVIRONMENTAL HEALTH IINDICATOR TO GUIDE PREVENTIVE
ACTIVITIES IN NINGXIA, PR CHINA
PLASMODIUM VIVAX ASSOCIATED ACUTE RESPIRATORY
DISTRESS SYNDROME AFTER EXTENDED TRAVEL IN
AFGHANISTAN
Yu R. Yang1, Philip S. Craig2, Dominique A. Vuitton3, Tao Sun1, Gail
M. Williams4, Zheng Z. Li1, Belchis Boufana2, Patrick Giraudoux3,
Yan B. Li1, Ling Huang1, Wei Zhang1, Donald P. McManus5
Jason D. Maguire1, Augustina I. Susanti2, Michael E. Fenton3,
Jeffrey B. Walker3, Robert V. Barthel3
U.S. Navy Expeditionary Medical Facility, Arifjan, Kuwait, 2Naval Medical
Research Unit #2, Jakarta, Indonesia, 3Naval Medical Center Portsmouth,
Portsmouth, VA, United States
Ningxia Medical College, Yinchuan City, Ningxia Hui Autonomous Region,
China, 2Medical Research Institute, University of Salford, Greater
Manchester, United Kingdom, 3WHO Collaborating Centre for Prevention
and Treatment of Human Echinococcosis, University of Franche-Comte and
University Hospital, Besancon, France, 4School of the Population Health,
University of Queensland, Brisbane, Australia, 5Queensland Institute of
Medical Research, Brisbane, Australia
77
DON’T PICK THE WILD MUSHROOMS! A RARE CASE OF LIVER
FAILURE DUE TO MUSHROOM POISONING IN NEW YORK
STATE
72
Taynet T. Febles, George Haralambou, Deborah Asnis, Ehsan Ali
COMPARISON OF RECOMBINANT AGB ELISA WITH
COMMERCIALLY AVAILABLE ELISA IGG IN THE DIAGNOSIS OF
CYSTIC ECHINOCOCCOSIS
Flushing Hospital Medical Center, Flushing, NY, United States
Enrico Brunetti1, Akira Ito2, Antonella Grisolia3, Francesca
Tamarozzi3, Yasuhito Sako2, S. Itoh2, Minoru Nakao2, Simona Gatti4,
Valeria Meroni1, Francesca Genco3, Carmine Tinelli4, Carlo Filice1
LEPROSY IN AGUA DE DIOS LEPROSARIUM - COLOMBIA,
2006: PATIENT CHARACTERISTICS AND APPLICATION OF
MOLECULAR METHODS FOR DRUG RESISTANCE
SURVEILLANCE AND STRAIN TYPING
78
1
University of Pavia- S.Matteo Hospital Foundation, Pavia, Italy, 2Asahikawa
Medical College, Asahikawa, Hokkaido, Japan, 3University of Pavia, Pavia,
Italy, 4S.Matteo Hospital Foundation, Pavia, Italy
Nora M. Cardona-Castro1, Juan C. Beltrán-Alzate1, Fernando
Torres-Jiménez2, Patrick J. Brennan3, Vara Vissa3
73
1
Instituto Colombiano de Medicina Tropical - CES, Sabaneta, Antioquia,
Colombia, 2Hospital Agua de Dios, Agua de Dios, Cundinamarca, Colombia,
3
PAIR V CONSERVATIVE SURGERY FOR UNCOMPLICATED
ECHINOCOCCAL CYSTS: EVALUATION OF COSTS IN ITALY
79
Enrico Brunetti1, Antonella Grisolia2, Giorgio Battelli3, Mario
Alessiani1, Carlo Filice1
MYIASIS EVEN IN A DESERT ENVIRONMENT?
SARCOPHAGIDAE AND OTHER LARVAL INFECTIONS IN
KUWAIT
1
University of Pavia- S.Matteo Hospital Foundation, Pavia, Italy, 2University of
Pavia, Pavia, Italy, 3University of Bologna, Bologna, Italy
Parsotam R. Hira1, Mahmoud M. Marzouk2, E. M. El-Aassar3, Faiza
M. Al-Ali3, Fatima A. Al-Shelahi3, Nabila Khalid1, Martin J. Hall4
74
PRELIMINARY RESULTS FROM A SURVEY ON KNOWLEDGE,
ATTITUDES AND PRACTICES REGARDING CLINICAL
MANAGEMENT OF CYSTIC ECHINOCOCCOSIS IN EUROPEAN,
NORTH AFRICAN AND MIDDLE EASTERN COUNTRIES
1
Department of Microbiology, Kuwait City, Kuwait, 2Department of Surgery,
Farwania Hospital, Kuwait City, Kuwait, 3Department of Microbiology,
Farwania Hospital, Kuwait City, Kuwait, 4Department of Entomology, Natural
History Museum, London, United Kingdom
80
Enrico Brunetti
University of Pavia, Pavia - On Behalf of the EchinoNet Group, Italy
BASELINE STUDY ON MALARIA DISEASE WITH ETHNIC
MINORITY GROUP IN RATTANAKIRI PROVINCE
75
IN VITRO AND IN VIVO ACTIVITY OF THE ANTI-CANCER
AGENT 2-METHOXYESTRADIOL (2ME2), EITHER ALONE OR IN
COMBINATION WITH ALBENDAZOLE, AGAINST
ECHINOCOCCUS MULTILOCULARIS METACESTODES
Bou Kheng Thavrin Thavrin
Martin Spicher, Arunasalam Naguleswaran, Andrew Hemphill
LARGE SCALE FOLLOW-UP AND MANAGEMENT OF HUMAN
VACCINATIONS BY WEB-BASED HIGH PERFORMANCE
DATABASE SOFTWARE IPGVAX: CONCEPT AND FIELD
EVALUATION IN GUADELOUPE (FRENCH CARIBES)
National Malaria Center, Phnom Penh, Cambodia
81
University of Berne, Berne, Switzerland
Ronald Perraut1, Fabrice Saintpere1, Bertrand Guillard1, Marcel
Sigiscar1, Olivier Angele2, Fabrice Renia3, Florelle Bradamantis3,
Patrice Richard3
1
Institut Pasteur Guadeloupe, Abymes, Guadeloupe, 2C2i Karaibes, Jarry,
Guadeloupe, 3Direction de la Santé et Developpement Social, Basse Terre,
Guadeloupe
63
Monday, November 5
1
1
Detailed Program
www.astmh.org
82
89
SCHOOL-BASE DENGUE CONTROL PILOT PROJECT IN
CAMBODIA
AZITHROMYCIN FOR THE TREATMENT OF AMERICAN
CUTANEOUS LEISHMANIASIS. PRE-CLINICAL AND CLINICAL
DATA
Chea MonThavy
Alejandro J. Krolewiecki1, Angel Sinagra2, Concepción Luna2,
Silvana Cajal3, Héctor Romero3, Marisa Juarez3, Tutsuyuki Mimori4,
Adriana Di Paolo3, Matsumoto Tamami4, Adelina Riarte2, David
Abraham5, Néstor Taranto3
83
GLUCOSE-6-PHOSPHATE DEHYDROGENASE (G6PD)
MUTATIONS IN CAMBODIA: G6PD VIANGCHAN (871G>A) IS
THE MOST COMMON VARIANT IN THE CAMBODIAN
POPULATION
1
Fundacion Huesped, Buenos Aires, Argentina, 2Instituto Nacional de
Parasitología “Mario Fatala Chaben”, Buenos Aires, Argentina, 3Instituto de
Investigaciones en Enfermedades Tropicales. Universidad Nacional de Salta,
Sede Regional Orán, Orán, Argentina, 4Departments of Microbiology and
Medical Technology, School of Health Sciences, Kumamoto University,
Kumamoto, Japan, 5Department of Microbiology and Immunology, Thomas
Jefferson University, Philadelphia, PA, United States
Chea Nguon
84
90
POLYMERASE CHAIN REACTION WITH TWO MOLECULAR
TARGETS IN MUCOSAL LEISHMANIASIS´ DIAGNOSIS: A
VALIDATION STUDY
THE PREVALENCE OF SUBSTANDARD AND COUNTERFEIT
PRESCRIPTION DRUGS IN CHENNAI (FORMER MADRAS), INDIA
Sandra H. Muvdi
Michael Seear1, Deepika Gandhi1, Roxanne Carr1, A. Dayal2, D.
Raghavan3
Centro Dermatologico Federico Lleras Acosta, Bogota, Colombia
1
Vancouver Children’s Hospital, Vancouver, BC, Canada, 2Apollo Hospital,
Chennai, India, 3Apollo Hospitall, Chennai, India
85
91
ZINC, COPPER AND IRON IMBALANCE IN INDIAN KALA-AZAR
Chandra S. Lal, Anil Kumar, Sanjay Kumar, Prabhat K. Sinha,
Krishna Pandey, Rakesh B. Verma, Pradeep Das
GRAM NEGATIVE BACILLARY INFECTIONS AMONG CANCER
PATIENTS AT AL-AMAL HOSPITAL IN DOHA/QATAR
Rajendra Memorial Research Institute of Medical Sciences, Patna, India
Adil Makkiya1, Maysaa Alkeilani1, Mohammad S. Al-Ani2
1
Department of Health Sciences/Qatar University, Doha, Qatar, 2Al-Amal
Hospital for Haemato-Oncology, Doha, Qatar
86
INTEGRATION OF INFORMATION TECHNOLOGIES IN CLINICAL
STUDIES IN NICARAGUA
92
William Aviles1, Oscar Ortega1, Guillermina Kuan2, Samantha
Hammond1, Josefina Coloma3, Eva Harris3
TANNINS, IONS, CATIONS AND MALARIASIS: OBSERVATIONS
AND THEORY
1
Deepak Bhatt Acharya
Sustainable Sciences Institute, Managua, Nicaragua, 2Socrates Flores
Vivas Health Center, Managua, Nicaragua, 3Division of Infectious Diseases,
United States
Orissa Research Laboratory, Bhubaneswar, Orissa, India
93
87
CASE MANAGEMENT AND OUTCOMES FOR CHILDREN
PRESENTING WITH FEVER AND NEGATIVE BLOOD SMEARS AT
GOVERNMENT HEALTH CENTERS IN UGANDA
TREATMENT PATTERNS AND THE COST IMPLICATIONS OF
CLINICAL, MICROSCOPY AND RAPID DIAGNOSTIC TESTS FOR
MALARIA DIAGNOSIS AT HEALTH FACILITIES IN ZAMBIA
Joaniter I. Nankabirwa1, Joan Kalyango1, Charles Karamagi1,
Moses Kamya1, Grant Dorsey2, Stefan Peterson3, Heidi Hopkins2
Pascalina Chanda
1
Makerere University, Kampala, Uganda, 2University of California, San
Francisco, San Francisco, CA, United States, 3International Health (IHCAR),
Karolinska Institutet, Stockholm, Sweden
National Malaria Control Centre, Lusaka, Zambia
88
94
ACTIVITIES OF ARTEMETHER-LUMEFANTRINE AND
AMODIAQUINE-SULFALENE-PYRIMETHAMINE AGAINST
SEXUAL STAGE PARASITES IN FALCIPARUM MALARIA IN
CHILDREN
EFFICACY AND PHARMACOKINETICS OF ARTEKIN
(DIHYDROARTEMISININ AND PIPERAQUINE) FOR THE
TREATMENT OF UNCOMPLICATED FALCIPARUM MALARIA IN
VIETNAM
Akintunde Sowunmi, Grace O. Gbotosho, Christian T. Happi,
Ahmed A. Adedeji, Olayinka M. Bolaji, Fatai A. Fehintola, Onikepe
A. Folarin, Tunde Balogun
Michael D. Edstein1, Nguyen V. Dao2, Nguyen D. Ngoa2, Nguyen
D. Hue2, Le T. Thuy2, Nguyen D. The2, Nguyen X. Thanh3, Bui Dai3,
Thomas Travers1
Department of Pharmacology and Therapeutics and Institute for Medical
Research and Training, University of Ibadan, Ibadan, Nigeria
1
Australian Army Malaria Institute, Brisbane, Australia, 2Military Hospital
175, Ho Chi Minh City, Vietnam, 3Military Institute of Hygiene and
Epidemiology, Hanoi, Vietnam
64
95
www.astmh.org
100
EFFECTIVENESS OF EXISTING NET DISTRIBUTION STRATEGIES
FOR ACHIEVING COMMUNITY-WIDE COVERAGE AND
PROTECTION IN RURAL TANZANIA
MALARIA TRANSMISSION INTENSITY AND MORBIDITY
PATTERNS IN PARTS OF THE IMO RIVER BASIN, SOUTH
EASTERN NIGERIA
Rashid A. Khatib1, Betty F. Ettling1, Gerry F. Killeen1, Salim M.
Abdulla1, Steven P. Kachur2
Uchechukwu M. Chukwuocha1, Ikechi N. Dozie2, Betram E.
Nwoke2, Celestine O. Onwuliri1, Okwuoma C. Abanobi1
1
1
101
96
TOXOPLASMA GONDII AND TOXOCARA SPP. CO-INFECTION
PERFORMANCE OF A MALARIA RAPID DIAGNOSTIC TEST VERSUS TRADITIONAL MICROSCOPY AMONG RURAL UGANDAN
OUTPATIENTS
Jeffrey L. Jones1, Deanna Kruzon-Moran2, Kim Won1, Marianna
Wilson1, Peter M. Schantz1
1
National Center for Health Statistics, Centers for Disease Control and
Prevention, Hyattsville, MD, United States
2
Lisa A. Mills1, Lydia R. Blank2, Joseph Kagaayi3, Simon Aluma3,
Joseph Shott4, John B. Bwanika3, Maria J. Wawer5, David
Serwadda3, Thomas C. Quinn4, Steven J. Reynolds4, Ronald L. Gray5
102
1
Johns Hopkins School of Medicine, Baltimore, MD, United States, 2Becton
Dickinson Diagnostic Systems, Cockeysville, MD, United States, 3Rakai
Health Sciences Program, Kalisizo, Uganda, 4National Institute of Allergy and
Infectious Diseases, Bethesda, MD, United States, 5Johns Hopkins School of
A QUANTITATIVE ALGORITHM FOR PRIORITIZATION OF
NATURALLY OCCURRING INFECTIOUS DISEASE THREATS TO
THE U.S. MILITARY
Tom J. Palys1, John Scovill2, Charles H. Hoke3, Jerry Abrams2, Kevin
Hanson4, Kathryn Clark4, Lynn W. Kitchen1, David W. Vaughn1, W.
Neal Burnette5
97
ECONOMIC ASSESSMENT OF PUTATIVE CONTROL STRATEGIES
AGAINST NEOSPORA CANINUM
1
Military Infectious Diseases Research Program, U.S. Army, Fort Detrick, MD,
United States, 2Science Applications International Corporation, McLean, VA,
United States, 3Anteon Corporation, Fairfax, VA, United States, 4Armed
Forces Medical Intelligence Center, Fort Detrick, MD, United States,
5
Molecular Pharmaceutics Corporation, Westlake Village, CA, United States
Bruno Gottstein1, Barbara Haesler2, Martin Reist2, Regula
Getrtraud2, Katharina Staerk2
1
Institute of Parasitology, Bern, Switzerland, 2Swiss Federal Veterinary Office,
Bern, Switzerland
103
98
MORTALITY RATES IN COHORTS OF CHILDREN TWO YEARS
AFTER SEVERE OR MILD MALARIA IN RURAL NORTHERN
GHANA
IMMUNIZATION WITH LEPTOSPIRAL IMMUNOGLOBULIN-LIKE
(LIG) PROTEIN WITH ALUMINIUM HYDROXIDE ADJUVANT
CONFERS STERILIZING IMMUNITY IN THE HAMSTER MODEL
FOR LEPTOSPIROSIS
Francis Anto1, Abraham Oduro1, Frank Atuguba1, Martin Adjuik1,
Nathan Mensah1, Thomas Anyorigiya1, Abraham Hodgson1,
Kwadwo A. Koram2
Flavia W. McBride1, Marco Medeiros2, Alan J. McBride1, Claudio P.
Figueira1, Gabriela Esteves2, Adenizar Chagas Júnior1, Cleiton
Santos1, James Matsunaga3, David Haake3, Akira Homma2, Ricardo
Galler2, Mitermayer G. Reis1, Albert I. Ko4
1
Navrongo Health Research Centre, Navrongo, Ghana, 2Noguchi Memorial
Institute for Medical Research, University of Ghana, Legon, Accra, Ghana
104
1
Oswaldo Cruz Foundation, Salvador, Brazil, 2Oswaldo Cruz Foundation, Rio
de Janeiro, Brazil, 3School of Medicine, University of California at Los
Angeles, Los Angeles, CA, United States, 4Weil Medical College of Cornell
INFORMATICS FOR DISEASE SURVEILLANCE IN DEVELOPING
COUNTRIES: EVALUATION OF THE EARLY WARNING
OUTBREAK RECOGNITION SYSTEM (EWORS)
99
Jean-Paul Chretien1, Khanthong Bounlu2, Wita Larasati3, Kanti
Laras3, Cecilia Mundaca4, Andreas Lescano4, Luis Suarez-Ognio5,
Jose Bolarte5, Cesar Munayco5, Jonathan Glass3, David Blazes4,
Howard Burkom6, Jacqueline Coberly6, Wayne Loschen6, Richard
Wojick6, Sheri Lewis6
MORBIDITY AND MORTALITY PATTERNS OF MEDICAL
ADMISSIONS IN A NIGERIAN SECONDARY HEALTH CARE
HOSPITAL
1
Aduragbenro D. Adedapo1, Funmi Fawole1, Afolabi Bamgboye1,
Omowunmi Y. Osinubi2
DoD Global Emerging Infections Surveillance and Response System, Silver
Spring, MD, United States, 2National Center for Laboratory and
Epidemiology, Ministry of Health, Vientiane, Lao People’s Democratic
Republic, 3US Naval Medical Research Unit-2, Jakarta, Indonesia, 4US Naval
Medical Research Center Detachment, Lima, Peru, 5Direccion General de
Epidemiologia, Ministry of Health, Peru, Lima, Peru, 6Johns Hopkins
University Applied Physics Laboratory, Laurel, MD, United States
1
College of Medicine, University of Ibadan, Nigeria, Ibadan, Nigeria,
University of Medicine and Dentistry of New Jersey - School of Public
Health, Piscataway, NJ, United States
2
65
Monday, November 5
Federal University of Technology, Owerri, Nigeria, 2Imo State University,
Owerri, Nigeria
Ifakara Health Research and Development Center, Dar es salaam, United
GA, United States
Detailed Program
www.astmh.org
Flaviviridae - Dengue
Nicaragua, 4Hospital Infantil Manuel de Jesus Rivera, Managua, Nicaragua,
University of California, San Diego, San Diego, CA, United States,
6
Direccion de Salud Ambiental y Epidemiologia, Ministry of Health,
Managua, Nicaragua, 7Division of Infectious Diseases, School of Public
Health, University of California, Berkeley, Berkeley, CA, United States
5
105
STUDY ON THE CORRELATIONS AMONG OF CLIMATE
FACTORS, MOSQUITO INDICES AND EPIDEMICS OF DENGUE
IN KAOHSIUNG, TAIWAN
111
Chuin-Shee Shang1, Chung-Ming Liu2, Yi-Shiuan Li1, ChwanChuen King1
VERY EFFECTIVE DENGUE VACCINES INCREASE THE
INCIDENCE OF DENGUE HEMORRHAGIC FEVER IN NONVACCINATED POPULATION: AN ISSUE OF MEDICAL ETHICS
AND SOCIAL EQUITY
1
Institute of Epidemiology, College of Public Health, National Taiwan
University, Taipei City, Taiwan, 2Global Change Researching Center, National
Taiwan University, Taipei City, Taiwan
Yoshiro Nagao
106
London School of Hygiene and Tropical Medicine, London, United Kingdom
112
SEROTYPE DETERMINATION AND ELUCIDATION OF NEW
DENGUE GENOTYPE MARKERS VIRUS THROUGH THE STUDY
OF THE NON-STRUCTURAL NS5 GENE
1
2
PREDICTIVE VALUE OF CLINICAL FINDINGS FOR THE EARLY
DIAGNOSIS OF DENGUE INFECTION
3
Catalina E. Gardella , Gerardo Pérez , Alejandro Cisneros , Joel
Navarrete4, Luis R. Ramírez5, Minerva Camacho-Nuez2, Maria de L.
Muñoz1
Luz Quiñones, Mary M. Ramos, Kay M. Tomashek, D. Fermín
Arguello, Aidsa Rivera, Jorge L. Muñoz-Jordan
Centers for Disease Control and Prevention, San Juan, PR, United States
1
Centro de Investigación y de Estudios Avanzados del IPN, Mexico D.F.,
Mexico, 2Universidad Autonoma de la Ciudad de Mexico, Mexico D.F.,
Mexico, 3Universidad Autónoma Bénito Juárez, Oaxaca, Mexico, 4División de
Epidemiología, IMSS, Mexico D.F., Mexico, 5Laboratorio Estatal de Salud
Pública, Oaxaca, Mexico
113
DENGUE INFECTION IN BHUTAN
Tandin Dorji1, In-Kyu Yoon2, Ananda Nisalak2, Richard Jarman2,
Khin S. Myint2, Robert V. Gibbons2
107
1
Department of Public Health, Thimphu, Bhutan, 2Armed Forces Research
Institute of Medical Sciences, Bangkok, Thailand
VIROLOGICAL AND SEROLOGICAL SURVEILLANCE OF DENGUE
FEVER/DENGUE HEMORRHAGIC FEVER IN THAILAND, 2003 TO
2006
114
Surapee Anantapreecha1, Sumalee Chanama1, Atchareeya A-nuegoonpipat1, Sirirat Naemkhunthot1, Pornsiri Boonpradit1, Walailuk
Sukprasert1, Ichiro Kurane2, Pathom Sawanpanyalert1
DEVELOPMENT OF A DEN-2 PDK-53-BASED CHIMERIC
TETRAVALENT VACCINE
Richard M. Kinney1, Claire Y.-H. Huang2, O’Neil Wiggan1, Shawn
J. Silengo2, A. P. Kalanidhi3, Jorge E. Osorio4, Dan T. Stinchcomb1
1
National Institute of Health, Department of Medical Sciences, Ministry of
Public Health, Nonthaburi, Thailand, 2Department of Virology I, National
Institute of Infectious Diseases, Toyama, Shinjuku-ku, Tokyo Japan
1
InViragen, Inc., Fort Collins, CO, United States, 2Division of Vector-Borne
Infectious Diseases of the Centers for Disease Control and Prevention, Fort
Collins, CO, United States, 3Shantha Biotechnics, Hyderabad, India,
4
University of Wisconsin, Madison, WI, United States
108
LONG-TERM CLIMATE AND ENDEMIC DENGUE TRANSMISSION
115
Michael Johansson1, Greg Glass2
1
Centers for Disease Control and Prevention, San Juan, PR, United States,
2
A PHASE 1 CLINICAL TRIAL OF A DENGUE-1 DNA VACCINE:
PRELIMINARY RESULTS
109
Charmagne Beckett1, Jeffrey Tjaden2, Timothy Burgess3, Janine
Danko1, Cindy Tamminga1, Monika Simmons1, Shuenn-Jue Wu1,
Peifang Sun1, Tadeusz Kochel1, Kanakatte Raviprakash1, Curtis
Hayes1, Kevin Porter1
COMMUNITY PARTICIPATION PROJECT FOR DENGUE
PREVENTION AND CONTROL IN PUERTO RICO: ENTOMOLOGIC
SURVEY RESULTS IN 2005-2006
1
Naval Medical Research Center, Silver Spring, MD, United States, 2Naval
Medical Research Unit #3, Cairo, Egypt, 3Naval Medical Research Unit #2,
Jakarta, Indonesia
Aurimar Ayala-López, Carmen Pérez-Guerra
116
110
PROTECTIVE EFFECT OF PRIMARY HETEROLOGOUS DENGUE
VIRUS INFECTION IN A MOUSE MODEL FOR SECONDARY
INFECTION
CHANGES IN PATTERNS OF DENGUE TRANSMISSION IN A
PEDIATRIC COHORT STUDY IN NICARAGUA
Guillermina Kuan1, Angel Balmaseda2, Oscar Ortega3, Nicole
Fitzpatrick3, William Aviles3, Andrea Nuñez2, Crisanta Rocha4,
Stephen Waterman5, Alcides Gonzalez2, Juan Jose Amador6,
Eva Harris7
Jennifer L. Kyle, Luhua Zhang, Scott J. Balsitis, P. Robert Beatty,
Eva Harris
1
Socrates Flores Vivas Health Center, Managua, Nicaragua, 2Departamento
de Virologia, Centro Nacional de Diagnostico y Referencia, Ministerio de
Salud, Managua, Nicaragua, 3Sustainable Sciences Institute, Managua,
66
117
www.astmh.org
123
MECHANISMS OF THROMBOCYTOPENIA IN DENGUE VIRUSINFECTED MICE
MOLECULAR CHARACTERIZATION OF ENVELOPE GENE FOR
HUMAN FATAL AND NON-FATAL YELLOW FEVER ISOLATES:
DETECTION OF SPECIFIC MUTATION AT POSITIONS E147 AND
E154
Scott J. Balsitis, Diana Flores, P. Robert Beatty, Eva Harris
Lívia C. Martins1, Ana C. Cruz1, Márcio R. Nunes1, Eliana V. da
Silva1, Jannifer O. Chiang1, Juarez A. Quaresma2, Pedro F.
Vasconcelos1
118
Instituto Evandro Chagas, Belém, Brazil, 2Universidade Federal do Pará,
Belém, Brazil
124
Blas Armien1, Evelia Quiroz1, Jose A. Suaya2, Vicente Bayard1,
Loyd Marchena1, Cornelio Campos3, Donald S. Shepard2
CHARACTERIZATION OF ANTIGENIC CHIMERIC ST. LOUIS
ENCEPHALITIS VIRUS/DENGUE VIRUS TYPE 4 RECOMBINANT
VIRUSES IN MICE AND MONKEYS
1
ICGES, Panama, Panama, 2Brandeis University, Boston, MA, United States,
Ministerio Salud, Panama, Panama
3
119
Joseph Blaney, Anthony Wlazlo, James Speicher,
Neeraj Sathe, Christopher Hanson, Brian Murphy, Stephen
Whitehead, Alexander Pletnev
INEFFICACY OF THE TREATMENT WITH A HIGH DOSE OF
IINTRAVENOUS IMMUNOGLOBULIN ON SEVERE
THROMBOCYTOPENIA IN PATIENTS WITH SECONDARY
DENGUE VIRUS INFECTION
National Institute of Allergy and Infectious Diseases, National Institutes of
Health, Bethesda, MD, United States
125
Kazunori Oishi1, Efren Dimaano2, Mariko Saito3, Filipinas
Natividad4
ASSAY FOR AND REPLICATION OF KARSHI (MAMMALIAN
TICK-BORNE FLAVIVIRUS GROUP) VIRUS IN MICE
1
Research Institute for Microbial Disease, Osaka University, Suita, Japan,
San Lazaro Hospital, Manila, Philippines, 3Institute of Tropical Medicine,
Nagasaki University, Nagasaki, Japan, 4St. Luke’s Medical Center, Quezon
City, Philippines
2
Chris Whitehouse1, Michael J. Turell1, Ashley Butler1, Carson
Baldwin1, Hannah Hottel1, Christopher Mores2
1
United States Army Medical Research Institute for Infectious Diseases, Fort
Detrick, MD, United States, 2Florida Medical Entomology Laboratory, Vero
Beach, FL, United States
120
IL-5 LEVELS AND PAIN INTENSITY CORRELATED TO HIGH
DENGUE 3 VIRAL LOADS
126
Renata T. Nascimento, Alessandra C. Gomes-Ruiz, Benedito A.
Fonseca
DEMONSTRATION OF RNA RECOMBINATION IN JAPANESE
ENCEPHALITIS VIRUS
FMRP -USP, Ribeirão Preto, Brazil
Ching-Kai Chuang, Wei-June Chen
Flaviviridae - Other
Chang Gung University, Tao-Yuan, Taiwan
127
121
ASSESSING THE IMPACT OF VIRAL ASSAYS METHODS
IN THE ESTIMATION OF INFECTION RATES FROM FIELD
CAUGHT MOSQUITOES
ENZYME-LINKED IMMUNOSORBENT ASSAY USING CROSSREACTIVITY REDUCED VIRUS-LIKE PARTICLES TO DETECT
ANTIBODIES AGAINST JAPANESE ENCEPHALITIS VIRUS
Dulce M. Bustamante, Kendra Pesko, Cynthia Lord
Shyan-Song Chiou1, Wayne D. Crill2, Li-Kuang Chen3,
Gwong-Jen. J. Chang2
Florida Medical Entomology Laboratory, University of Florida, Vero Beach, FL,
United States
1
Graduate Institute of Veterinary Public Health, National Chung Hsing
University, Taichung, Taiwan, 2Arboviral Diseases Branch, Division of VectorBorne Infectious Diseases, National Center for Zoonotic, Vector-Borne, and
Enteric Diseases, Centers for Disease Control and Prevention, Public Health
Service, U.S. Department of Health and Human Service, Fort Collins, CO,
United States, 3College of Medicine, Tzu-Ch University, Hualien, Taiwan
122
SAFETY AND IMMUNOGENICITY OF CONCOMITANT
VACCINATION WITH IC51 AND HEPATITIS A VACCINE IN
HEALTHY SUBJECTS. A SINGLE-BLIND RANDOMIZED
CONTROLLED PHASE 3 STUDY
128
Claudia Lehner1, Gerald Eder2, Alessandra Formica1, Astrid
Kaltenböck1, Christoph Klade1, Herwig Kollaritsch3, Maria PaulkeKorinek3, Frank von Sonnenburg4, Erich Tauber1
EVALUATION OF VIRUS ISOLATION TECHNIQUES FOR
JAPANESE ENCEPHALITIS
Jaimie S. Robinson, Jason O. Velez, Barbara W. Johnson
1
Intercell AG, Vienna, Austria, 2Karl Landsteiner Institut für
Infektionsepidemiologie und Impfwesen, St. Pölten, Austria, 3Department of
Specific Prophylaxis and Tropical Medicine at the Institute of
Pathophysiology, Medical University Vienna, Vienna, Austria, 4Department of
Infectious Diseases and Tropical Medicine, University of Munich, Munich,
Germany
67
Monday, November 5
1
CLINICAL CHARACTERIZATION AND ECONOMIC IMPACT OF
THE DENGUE EPIDEMIC IN PANAMA IN THE YEAR 2005
Detailed Program
www.astmh.org
129
134
SEROLOGICAL EVIDENCE OF POWASSAN VIRUS
TRANSMISSION IN SMALL MAMMALS COLLECTED IN RUSSIA,
ALASKA AND THE WESTERN UNITED STATES
1
2
NATIONAL SEROPREVALENCE AND RISK FACTORS FOR
ZOONOTIC TOXOCARA SPP. INFECTION
Kimberly Won1, Deanna Kruszon-Moran2, Peter Schantz1,
Jeffrey Jones1
1
Robert A. Nofchissey , Joseph Cook , Diane Goade , Andrew
Hope2, Albina Tsvetkova3, Gregory D. Ebel1
1
Centers for Disease Control and Prevention, Hyattsville, MD, United States
2
1
University of New Mexico School of Medicine, Albuquerque, NM, United
States, 2Museum of Southwestern Biology, Albuquerque, NM, United States,
3
Institute of Biology, Moscow, Russian Federation
135
DEVELOPMENT OF A RAPID AND SPECIFIC
IMMUNODIAGNOSTIC ASSAY FOR STRONGYLOIDES
INFECTION USING A LUCIFERASE IMMUNOPRECIPITATION
SYSTEM
130
POTENTIAL FOR INTRODUCTION AND ESTABLISHMENT OF
JAPANESE ENCEPHALITIS VIRUS INTO NORTH AMERICA
Frank Mannix, Dawn W. Wesson
Roshan Ramanathan, Peter B. Burbelo, Michael J. Iadarola,
Franklin A. Neva, Thomas B. Nutman
Tulane University School of Public Health and Tropical Medicine, New
Orleans, LA, United States
131
136
DIFFERENT PATTERN OF LIVER LESIONS IN GOLDEN
HAMSTERS FOR YELLOW FEVER FATAL AND NON-FATAL
HUMAN ISOLATES
PCR ASSAY FOR THE DETECTION OF ANGIOSTRONGYLUS
COSTARICENSIS DNA
Livia C. Martins1, Ana C. Cruz1, Eliana V. da Silva1,
Marcio R. Nunes1, Jannifer O. Chiang1, Juarez A. Quaresma2,
Pedro F. Vasconcelos1
Smith College, Northampton, MA, United States
Maria Gabriela Solano, Steven A. Williams
(ACMCIP Abstract)
137
1
Instituto Evandro Chagas, Belém, Brazil, 2Universidade Federal do Para,
Belém, Brazil
MODULATION OF THE INNATE AND ACQUIRED IMMUNE
RESPONSE IN THE MICE REINFECTED WITH STRONGYLOIDES
VENEZUELENSIS
Helminths – Nematodes – Intestinal Nematodes
132
Eleuza R. Machado1, Daniela C. Carlos2, Walter M. Turato2, Elaine
V. Lourenço3, Daniela I. Souza2, Carlos A. Sorgi2, Érika V. da Silva2,
Simone G. Ramos4, Marlene T. Ueta5, Lúcia H. Faccioli2
DETERMINATION OF IMMOBILIZATION AND LETHAL
DOSES (MG/ML) OF ERYNGIAL (TRANS-2-DODECENAL),
USING STRONGYLOIDES STERCORALIS, HAEMONCHUS
CONTORTUS, ANCYLOSTOMA CANINUM AND
PARASTRONGYLOIDES TRICHOSURI INFECTIVE LARVAE
IN VITRO, AND A COMPARISON OF ITS ANTHELMINTIC
ACTIVITY WITH IVERMECTIN
1
Department of Phatology, Tufts University School of Medicine, MA, United
States, 2Departamento de Análisis Clinicas, Toxicólogicas e Bromatológicas,
Fac. de Ciências Farmacêuticas de Ribeirão Preto, Brazil, 3Departamento de
Biologia Celular, Molecular e Bioagentes Patogênicos, Fac. de Medicina de
Ribeirão Preto, Brazil, 4Departamento de Patologia, Fac. de Medicina de
Ribeirão Preto, Brazil, 5Departamento de Parasitologia, Instituto de Biologia Universidade de Campinas, Brazil
Wayne M. Forbes1, Ralph D. Robinson2, Paul B. Reese3
1
(ACMCIP Abstract)
Department of Biology, Slippery Rock University of Pennsylvania, Slippery
Rock, PA, United States, 2Department of Life Sciences, The University of the
West Indies (Mona), Kingston, Jamaica, 3Department of Chemistry, The
University of the West Indies (Mona), Kingston, Jamaica
HIV
138
133
HOUSING CONDITONS AND SURVIVAL OF PEOPLE WITH HIV
INFECTION IN THE DOMINICAN REPUBLIC
DEVELOPMENT OF DNA ASSAYS, IN SOIL-TRANSMITTED
NEMATODE PARASITES OF HUMANS, FOR THE DETECTION OF
SINGLE NUCLEOTIDE POLYMORPHISMS (SNPS) ASSOCIATED
WITH BENZIMIDAZOLE RESISTANCE
Michael N. Dohn, Anita L. Dohn, Luisa Reyes
Clínica Esperanza y Caridad, San Pedro de Macorís, Dominican Republic
139
Aissatou Diawara1, Lesley J. Drake2, Richard R. Suswillo2, Don A.
Bundy3, Roger K. Prichard1
1
McGill, Montreal, QC, Canada, 2Imperial College School of Medicine,
London, United Kingdom, 3World Bank, Washington DC, United States
THE SIX SYSTEMIC COMPONENTS FOR DEVELOPMENT AND
IMPLEMENTATION OF SUCCESSFUL INTERNATIONAL PUBLIC
HEALTH REGIMES
(ACMCIP Abstract)
E. Asher Balkin
Ohio University, Athens, OH, United States
68
www.astmh.org
147
Kinetoplastida – Molecular Biology and Immunology
140
CHARACTERIZATION OF TRYPANOSOMA BRUCEI CA2+
CHANNNEL: A POTENTIAL DRUG AND VACCINE TARGET IN
TRYPANOSOMES
IDENTIFICATION AND CHARACTERIZATION OF TWO 14-3-3
PROTEINS IN THE HUMAN PARASITE TRYPANOSOMA CRUZI
Bethany A. Peel, Joy Sturteva
Kiantra I. Ramey, Nana Wilson, Lucky Nwankwo, Zuzana
Kucerova, Winston Thompson, Jonathan K. Stiles
Louisiana State University Health Sciences Center, New Orleans, LA, United
States
148
141
THE DETERMINATION OF SPECIES AND GENOTYPES OF
LEISHMANIA SPP. USING PCR-RFLP ASSAYS IN CLINICAL
SAMPLES OF PATIENTS AND RESERVOIRS IN TURKEY
ANTIGEN DISCOVERY FOR CONTROL OF VISCERAL
LEISHMANIASIS
Yasuyuki Goto, Rhea N. Coler, Sylvie Bertholet, Steven G. Reed
Koray Gunes1, Seray Ozensoy Toz1, Hatice Ertabaklar2, Sema
Ertug2, Yusuf Ozbel1
Infectious Disease Research Institute, Seattle, WA, United States
1
Ege University Medical School, Izmir, Turkey, 2Adnan Menderes University
Medical School, Aydin, Turkey
(ACMCIP Abstract)
142
(ACMCIP Abstract)
ROLE OF MAP KINASE ERK IN ALTERING DENDRITIC CELL
MATURATION AND CELL-MEDIATED IMMUNE RESPONSE TO
LEISHMANIA AMAZONENSIS INFECTION
149
THE ROLE OF ACRIFLAVIN IN THE PROLIFERATION OR
INHIBITION OF TRYPANOSOMA MUSCULI BY INDUCING
APOPTOSIS WITH SPECIFIC BINDING AFFINITY TO KDNA OF
THE PARASITE IN VITRO AND IN VIVO
Paola M. Boggiatto, Fei Jei, Rami Mukbel, Mousumi Ghosh,
Douglas E. Jones, Christine A. Petersen
Dereje D. Gimite, Mohammad Ashraf, Clarence M. Lee
143
Howard University, Washington, DC, United States
THE ROLE OF B CELLS IN THE CELL-MEDIATED IMMUNE
RESPONSE TO LEISHMANIA AMAZONENSIS
(ACMCIP Abstract)
150
Katherine N. Gibson-Corley, Rami Mukbel, Christine Petersen,
Douglas Jones
THE ROLE OF LIVER-X RECEPTOR (LXR) IN LEISHMANIA
CHAGASI INFECTION IN MICE
Kevin W. Bruhn1, Chaitra Marathe2, Thu A. Tran1, Peter Tontonoz2,
Noah Craft1
144
THE MAJOR SURFACE PROTEASE OF THE AMASTIGOTE STAGE
OF LEISHMANIA CHAGASI
1
Los Angeles Biomedical Research Institute, Torrance, CA, United States,
University of California, Los Angeles, Los Angeles, CA, United States
2
Chia-Hung Christine Hsiao1, Chaoqun Yao2, Patricia A. Storlie1,
John E. Donelson1, Mary E. Wilson2
(ACMCIP Abstract)
151
1
University of Iowa, Iowa City, IA, United States, 2The VA Medical Center
and University of Iowa, Iowa City, IA, United States
EFFICACY OF A DNA VACCINE AGAINST LEISHMANIA
MEXICANA IN GOLDEN HAMSTERS
146
Wilberth G. Chalé-Balboa, Juan L. Tzec-Arjona, Mirza Mut-Martin,
Maria J. Ramirez-Sierra, Maria Garcia-Miss, Eric Dumonteil
POST TRANSLATIONAL REGULATION OF MYOBLAST CYCLIN
D1 BY TRYPANOSOMA CRUZI
Universidad Autonoma de Yucatan, Merida, Yucatan, Mexico
Boumediene Bouzahzah1, Vyascheslav Yurchenko1,
Fnu Nagajyothi1, Shankar Mukherjee1, James Hulit1,
Moshe Sadofsky1, Vicki L. Braunstein1, Louis M. Weiss1,
Chris Albanese2, Herbert B. Tanowitz1
(ACMCIP Abstract)
1
Albert Einstein College of Medicine, Bronx, NY, United States, 2Georgetown
University Medical Center, Washington, DC, United States
(ACMCIP Abstract)
69
Monday, November 5
(ACMCIP Abstract)
(ACMCIP Abstract)
Detailed Program
www.astmh.org
152
158
EVALUATION OF THE EFFICACY OF A COMBINATION OF DNA
VACCINES ENCODING TSA-1 AND TC24 ANTIGENS IN MICE
INFECTED WITH TRYPANOSOMA CRUZI
PLASMODIUM FALCIPARUM LIVER STAGE ANTIGEN-1 IS
CROSSLINKED BY TISSUE TRANSGLUTAMINASE
William S. Nicoll1, John B. Sacci2, Carlo Rodolfo3, Giuseppina
DiGiacomo3, Mauro Piacentini3, Michael R. Hollingdale4,
David E. Lanar1
Juan L. Tzec-Arjona, Patricia Lopez-Lopez,
Wilberth G. Chale-Balboa, Gilma Sanchez-Burgos,
Maria J. Ramírez-Sierra, Eric Dumonteil
1
3
University of Rome Tor Vergata, Rome, Italy, 4National Institutes of Health,
Rockville, MD, United States
2
Universidad Autonoma de Yucatan, Merida, Yucatan, Mexico
(ACMCIP Abstract)
153
(ACMCIP Abstract)
159
T-CELL EPITOPE MAPPING OF MAJOR MSP-133 ALLELES IN
HUMAN CORD BLOOD FROM KENYAN NEWBORNS
REDUCED RISK OF P. VIVAX AND P. MALARIAE INFECTIONS
ASSOCIATED WITH BAND 3 DELETION IN PAPUA NEW
GUINEAN CHILDREN
Indu Malhotra1, Kevin Steiner1, Peter Mungai1, Alex Wamachi2,
Mzungu Kafwani3, Eric Muchiri3, Christopher L. King1
1
Medical Research Institute, Nairobi, Kenya, 3Division of Vector Borne
Diseases, Nairobi, Kenya
Ivo Mueller1, Enmoore Lin1, Jennifer Cole-Tobian2, Danielle
Stanisic3, Elijah Dabod1, John C. Reeder1, Christopher C. King2,
Peter A. Zimmerman2, Pascal Michon1
154
1
PNG Institute of Medical Research, Goroka, Papua New Guinea, 2Centre of
Global Health and Diseases, Case Western Reserve University, Cleveland,
OH, United States, 3Walter & Eliza Hall Institute, Melbourne, Australia
RNAI OF EXTRACELLULAR MATRIX GENES THAT ARE
REGULATED BY TRYPANOSOMA CRUZI BLOCKS T. CRUZI
INFECTION
160
Kaneatra J. Simmons, Pius N. Nde, M. Nia Madison, Yuliya
Kleshchenko, Maria F. Lima, Fernando Villalta
INTEGRATING QUANTITATIVE TRAIT LOCI (QTL) WITH WHOLEGENOME DATA TO IDENTIFY CANDIDATE GENES CONTROLLING GROWTH TRAITS IN PLASMODIUM FALCIPARUM
(ACMCIP Abstract)
Heather B. Reilly, Mark A. Wacker, Asako Tan, Joseph M.
Gonzales, Michael T. Ferdig
Malaria – Biology and Pathogenesis
University of Notre Dame, Notre Dame, IN, United States
155
161
THE ROLE OF OXIDATIVE STRESS AND MALARIA INFECTION
ON ANAEMIA IN PREGNANCY
MULTI-FACETED IMPACT OF MSP-1P42 SPECIFIC ANTIBODIES
ON BLOOD STAGES OF P. FALCIPARUM
Olusegun M. Akanbi1, Olusegun G. Ademowo2, Alex B. Odaibo3
Elke S. Bergmann-Leitner, Elizabeth H. Duncan, Evelina Angov
1
Department of Environmental Biology and Fisheries, Adekunle Ajasin
University, Akungba Akoko, Ondo State, Nigeria, 2Institute for Advanced
Medical Research and Training, University of Ibadan, Ibadan, Oyo State,
Nigeria, 3Department of Zoology, Parasitology Unit, University of Ibadan,
Ibadan, Oyo State, Nigeria
162
IDENTIFICATION OF A NOVEL FAMILY OF VARIANT SURFACE
ANTIGENS IN PLASMODIUM FALCIPARUM
156
Amanda K. Lukens1, Daniel E. Neafsey2, Stephen F. Schaffner2,
David DeCaprio2, Sarah K. Volkman1, Padis C. Sabeti2, Danny A.
Milner1, Johanna P. Daily1, Ousmane Sarr3, Daouda Ndiaye3,
Omar Ndir3, Soulyemane Mboup3, Danny Park2,
Roger C. Wiegand2, Bruce W. Birren2, James E. Galagan2,
Eric S. Lander2, Dyann F. Wirth1
INDUCTION OF PLASMODIUM SPOROZOITE MOTILITY BY
ALBUMIN IS ASSOCIATED WITH MOBILIZATION OF
INTRACELLULAR CALCIUM
Chahnaz Kebaier, Jerome Vanderberg
1
Harvard School of Public Health, Boston, MA, United States, 2The Broad
Institute of Harvard and MIT, Cambridge, MA, United States, 3Faculty of
Medicine and Pharmacy, Cheikh Anta Diop University, Dakar, Senegal
157
MAGNETIC SEPARATION: A VERY EFFECTICE METHOD FOR
THE SYNCHRONIZATION OF PLASMODIUM FALCIPARUM IN
CULTURE
(ACMCIP Abstract)
Jae-Won Park1, Sun-Young Ahn1, Mi-Young Shin1, Young-A Kim1,
Ji-Ae Yoo1, Dong-Hwan Kwak1, Yoon-Jae Jung1, Joon-Sup Yeom2
1
Gachon Medical School, Incheon, Republic of Korea, 2Sungkyunkwan
University School of Medicine, Seoul, Republic of Korea
(ACMCIP Abstract)
70
163
www.astmh.org
168
VARIANT MEROZOITE PROTEIN EXPRESSION IS ASSOCIATED
WITH ERYTHROCYTE INVASION PHENOTYPES IN
PLASMODIUM FALCIPARUM ISOLATES FROM TANZANIA
PHARMACOKINETIC PROFILES OF INJECTABLE ARTESUNATE
(AS) IN THE PREGNANT AND NON-PREGNANT RATS IN RELATION TO ITS EMBRYOTOXICITY
Amy K. Bei1, Christopher D. Membi2, Julian C. Rayner3, Marycelina
Mubi2, Billy Ngasala2, Ali A. Sultan4, Zul Premji2, Manoj T.
Duraisingh1
Qigui Li, Yuanzheng Si, Kirsten Smith, Qiang Zeng, Peter Weina
EFFICACY, TOXICITY AND THERAPEUTIC INDICES OF ARTESUNATE (AS) AND DIHYDROARTEMISININ (DHA) IN P.
BERGHEI INFECTED AND UNINFECTED RATS
(ACMCIP Abstract)
Lisa Xie, Qigui Li, Jing Zhang, Peter Weina
164
STATINS ENHANCE HOST INFLAMMATORY RESPONSES TO
PLASMODIUM FALCIPARUM GPI IN VITRO AND DYSREGULATE
INNATE RESPONSE TO BLOOD STAGE INFECTION IN VIVO
170
EFFICACY EVALUATIONS OF 13 METABOLITES OF ARTESUNATE IN CULTURE WITH VARIOUS CLONES AND ISOLATES
OF P. FALCIPARUM
Andrew Helmers, W. Conrad Liles, Kevin C. Kain
McLaughlin-Rotman Centre for Global Health, University of Toronto,
Toronto, ON, Canada
Jing Zhang, Lisa Xie, Lucia Gerena, Peter Weina, Qigui Li
(ACMCIP Abstract)
Malaria – Drug Development
171
165
ISOLATED MITOCHONDRIA FROM P. FALCIPARUM WITH
CYTOCHROME B MUTATIONS PRESENT AN ALTERED SENSITIVITY TO ANTIMALARIAL 4-(1H)-PYRIDONES
P. FALCIPARUM HISTONE DEACETYLASES: ENZYMES
INVOLVED IN GENE REGULATION AS NEW ANTIMALARIAL
DRUG TARGETS
Francisco-Javier Gamo, Laura Sanz, Maria-Jose Lafuente, Alfonso
Mendoza, Cristina De-Cozar, Ane Rodriguez, Jose-Luis Llergo, Eva
Lopez, Federico Gomez-de-las-Heras, Jose-Francisco Garcia-Bustos
Kathy T. Andrews1, Thanh N. Tran2, Andrew Lucke3, Pia
Kahnberg3, GT Lee3, Tina Skinner-Adams3, Donald L. Gardiner1,
David P. Fairlie3
GlaxoSmithKline, Diseases of the Developing World, Tres Cantos (Madrid),
Spain
1
Queensland Institute of Medical Research, Herston, Queensland, Australia,
Queensland Institute of Medical Research and Griffith University, Herston,
Queensland, Australia, 3University of Queensland, St. Lucia, Queensland,
Australia
172
2
2-STAGE FRACTIONAL FACTORIAL DESIGN TO INVESTIGATE
FACTORS INFLUENCING THE EFFICACY OF PAFURAMIDINE
MALEATE FOR THE TREATMENT OF UNCOMPLICATED P.
FALCIPARUM MALARIA
166
POTENT ANTIMALARIAL ACTIVITY OF THE A/T-SPECIFIC
ALKYLATING AGENT AS-I-145 AGAINST PLASMODIUM IN
VITRO AND IN VIVO
1
2
Jeffrey D. Isaacson
Webbwrites, Batavia, IL, United States
3
173
Stephanie K. Yanow , Lisa A. Purcell , Ana Rodriguez , Moses
Lee4, Terry W. Spithill2
PRE-CLINICAL MONKEY TOXICITY STUDY OF JPC-2056-I, A
THIRD GENERATION ANTIFOLATE
1
Provincial Laboratory for Public Health (Microbiology), Edmonton, AB,
Canada, 2McGill University, Montreal, QC, Canada, 3New York University
School of Medicine, New York, NY, United States, 4Hope College, Holland,
MI, United States
Guy A. Schiehser1, Jacek Terpinski1, Arba L. Ager2, Alan J. Magill3,
Wil K. Milhous3, Colin Ohrt3, David L. Saunders3, Dennis E. Kyle4,
Michael D. Edstein5, Karl H. Rieckmann5, G. Dennis Shanks5, Carol
H. Sibley6, Craig J. Canfield7, Laura R. Jacobus1, David P. Jacobus1
167
1
Jacobus Pharmaceutical Co., Inc., Princeton, NJ, United States, 2University
of Miami School of Medicine, Miami, FL, United States, 3Walter Reed Army
Institute of Research, Silver Spring, MD, United States, 4University of South
Florida, Tampa, FL, United States, 5Australian Army Malaria Institute,
Enoggera, Queensland, Australia, 6University of Washington, Seattle, WA,
United States, 7Pharmaceutical Systems, Inc., Talent, OR, United States
PHARMACOKINETIC COMPARISON OF ARTESUNATE (AS) FOLLOWING MULTIPLE INTRAVENOUS INJECTIONS IN THE P.
BERGHEI INFECTED AND UNINFECTED RATS
Qigui Li, Lisa Xie, Jing Zhang, Peter Weina
71
Monday, November 5
169
1
Harvard School of Public Health, Boston, MA, United States, 2Muhimbili
University College of Health Sciences, Dar es Salaam, United Republic of
Tanzania, 3University of Alabama at Birmingham, Birmingham, AL, United
States, 4Weill Cornell Medical College in Qatar, Doha, Qatar
Detailed Program
www.astmh.org
174
Gynaecology, College of Medicine, University of Ibadan, Ibadan, Nigeria,
3
Department of Medical Microbiology, College of Medicine, University of
Ibadan, Ibadan, Nigeria, 4IMRAT, College of Medicine, University of Ibadan,
Ibadan, Nigeria
PRE-CLINICAL MOUSE TOXICITY STUDY OF JPC-2056-I, A
THIRD GENERATION ANTIFOLATE ANTIMALARIAL
Guy A. Schiehser1, Jacek Terpinski1, Arba L. Ager2, Alan J. Magill3,
Wil K. Milhous3, Colin Ohrt3, David L. Saunders3, Dennis E. Kyle4,
Michael D. Edstein5, Karl H. Rieckmann5, G. Dennis Shanks5, Carol
H. Sibley6, Craig J. Canfield7, Laura R. Jacobus1, David P. Jacobus1
180
ASSOCIATION OF MALARIA INFECTION WITH MOTOR AND
LANGUAGE DEVELOPMENT AMONG PRESCHOOL CHILDREN
IN ZANZIBAR
1
Jacobus Pharmaceutical Co., Inc., Princeton, NJ, United States, 2University
of Miami School of Medicine, Miami, FL, United States, 3Walter Reed Army
Institute of Research, Silver Spring, MD, United States, 4University of South
Florida, Tampa, FL, United States, 5Australian Army Malaria Institute,
Enoggera, Queensland, Australia, 6University of Washington, Seattle, WA,
United States, 7Pharmaceutical Systems, Inc., Talent, OR, United States
Anna Minta1, Rebecca J. Stoltzfus2, Hababu Chwaya3, Marco
Albonico4, James Tielsch1
1
States, 2Cornell University, Ithaca, NY, United States, 3United Nations
Children’s Fund, Zanzibar, United Republic of Tanzania, 4Ivo de Carneri
Foundation, Milan, Italy
Malaria - Epidemiology
181
175
MULTIPLEX EVALUATION OF SINGLE NUCLEOTIDE POLYMORPHISMS TO DIFFERENTIATE BETWEEN NEW AND RECRUDESCENT INFECTIONS IN CLINICAL TRIALS OF ANTIMALARIAL
DRUGS AGAINST PLASMODIUM FALCIPARUM
MALARIA CONTROL IN THE MUNICIPALITY OF SAN ESTEBAN,
HONDURAS, CENTRAL AMERICA
Christine E. Bell1, Stanley O. Foster1, Laurence Slutsker2, Raymond
Beach2, German Jimenez3, Maria Sarmiento4
Jeana T. DaRe1, John Heintz1, Drew Kouri1, Peter Thomas1, Harin
Karunajeewa2, Tim Davis2, Enmoore Lin3, Ivo Mueller3, Peter A.
Zimmerman1
1
Rollins School of Public Health, Emory University, Atlanta, GA, United
States, 2 Centers for Disease Control and Prevention/CCID/NCZVED, Atlanta,
GA, United States, 3Honduras Outreach Inc., San Esteban, Honduras,
4
Municipal Health Promoter, San Esteban, Honduras
1
Case Western Reserve University, Cleveland, OH, United States, 2University
of Western Australia, Crawley, Australia, 3Papua New Guinea Institute of
Medical Research, Goroka, Papua New Guinea
176
182
CONGENITAL PLASMODIUM FALCIPARUM INFECTION IN
NEONATES IN MUHEZA DISTRICT, TANZANIA
SEASONAL VARIATIONS IN PLASMODIUM SPECIES.
CASE STUDY OF A RURAL PERIPHERAL HOSPITAL FROM
CENTRAL INDIA
Grace W. Mwangoka
Ifakara Health Research and Development Centre, Dar es salaam, United
Neeru Singh1, Puspendra Pal Singh1, Ajay Saxena1, Mrigendra Pal
Singh1, R.G. Chaurasia2, A.P. Dash3
(ACMCIP Abstract)
177
1
National Institute of Malaria Research Field Station, Indian Council of
Medical Research (ICMR), Jabalpur, India, 2Civil Hospital Maihar, Satna,
Madhya Pradesh, India, 3National Institute of Malaria Research, Indian
Council of Medical Research (ICMR), Delhi, India
MALARIA PARASITE PREVALENCE IN THE ARTIBONITE VALLEY
OF HAITI DURING THE RAINY SEASON, 2006
Thomas P. Eisele1, Joe Keating1, Adam Bennett1, Berlin Londono1,
Dawn Johnson2, Christina Lafontant2, Donald J. Krogstad1
183
1
Tulane University, New Orleans, LA, United States, 2Hopital Albert
Schweitzer, Deschapelles, Haiti
MALARIA IN FOREST VILLAGES OF MANDLA AND DINDORI
DISTRICTS IN CENTRAL INDIA (MADHYA PRADESH)
Gyan Chand1, Nutan Nanda2, Mrigendra Pal Singh3, Aditya Prasad
Dash2, Neeru Singh3
178
FACTORS ASSOCIATED WITH THE PROVISION OF APPROPRIATE ANTIMALARIAL THERAPY FOR CHILDREN UNDER FIVE IN
NIGERIA
1
Regional Medical Research Center for Tribal (ICMR), Jabalpur, India,
National Institute of Malaria Research, Indian Council of Medical Research
(ICMR), Delhi, India, 3National Institute of Malaria Research Field Station,
Indian Council of Medical Research (ICMR), Jabalpur, India
2
Gloria E. Oramasionwu, William Brieger
184
179
MALARIA RELATED KNOWLEDGE, PERCEPTIONS, AND PRACTICES IN THE ARTIBONITE VALLEY OF HAITI
PREVALENCE OF MALARIA AT BOOKING AMONG ANTENATAL
PATIENTS IN A SECONDARY HEALTH CARE FACILITY IN
IBADAN, NIGERIA
Joseph Keating1, Thom Eisele1, Adam Bennett1, Dawn Johnson2,
Christina Lafontant2, Kate Macintyre1
1
1
Tulane University, New Orleans, LA, United States, 2Hopital Albert Sweitzer,
Deschapelles, Haiti
2
Catherine O. Falade , Oladapo Olayemi , Hannah O. DadaAdegbola3, Christopher O. Aimaku2, Olusegun G. Ademowo4,
Lateef A. Salako1
1
Department of Pharmacology and Therapeutics, College of Medicine,
University of Ibadan, Ibadan, Nigeria, 2Department of Obstetrics and
72
185
www.astmh.org
191
SIMULATION OF MALARIA TRANSMISSION AMONG HOUSEHOLDS IN A THAILAND VILLAGE USING REMOTELY SENSED
PARAMETERS
IMMUNOEPIDEMIOLOGY OF PVRII, A PUTATIVE VACCINE CANDIDATE REPRESENTING PLASMODIUM VIVAX DUFFY BINDING
PROTEIN, IN SRI LANKA
Richard Kiang1, Farida Adimi1, Gabriela Zollner2, Russell Coleman2
Prasad H. Premaratne1, Sajani Dias1, Shiroma M. Handunnetti2,
Syed S. Yazdani3, Chetan E. Chitnis3, Preethi V. Randeniya1
2
NASA Goddard Space Flight Center, Greenbelt, MD, United States, Walter
Reed Army Institute of Research, Silver Spring, MD, United States
1
Department of Zoology, University of Colombo, Sri Lanka, Colombo, Sri
Lanka, 2Malaria Research Unit, University of Colombo, Sri Lanka, Colombo,
Sri Lanka, 3International Centre for Genetic Engineering and Biotechnology,
New Delhi, India
186
MALARIA KNOWLEDGE, ATTITUDE AND PRACTICES AND
PREVALENCE OF ANOPHELES IN THE FOREST OF REGION OF
GUINEA, WEST AFRICA
(ACMCIP Abstract)
192
Frederique A. Jacquerioz1, Camille Edwards1, Emily Jentes1, James
Wallace1, Noumouny Sacko2, Karfalla Kourouma2, Jean Sagno2,
Mamadi Coulibaly2, Dawn Wesson1, Daniel G. Bausch1
INTERFERON GAMMA RESPONSE TO A T-CELL EPITOPE OF P.
FALCIPARUM GLUTAMATE RICH PROTEIN (GLURP) CORRELATES WITH PROTECTION FROM CLINICAL MALARIA IN
GHANAIAN CHILDREN
1
Tulane School of Public Health and Tropical Medicine, New Orleans, LA,
United States, 2International Center for Research on Tropical Infections in
Guinea, N’Zérékoré, Guinea
Helena Nartey1, Michael Ofori1, Kwadwo Koram2, Bartholomew
D. Akanmori1, Dominic Edoh3, Ed Remarque4, Daniel Dodoo1,
Michael Theisen5
187
1
Noguchi Memorial Institute for Medical Research, Immunology
Department, University of Ghana, Accra, Ghana, 2Noguchi Memorial
Institute for Medical Research, Epidemiology Department, University of
Ghana, Legon, Accra, Ghana, 3Zoology Department, University of Ghana,
Legon, Accra, Ghana, 4Biomedical Primate Research Centre, Netherlands,
Netherlands Antilles, 5Department of Infectious Disease Immunology, State
Serum Institute, Denmark, Denmark
HIGH PREVALENCE OF ASYMPTOMATIC MALARIA INFECTIONS
IN THE PAPUA NEW GUINEA DEFENCE FORCE
Edwin Siu1, Andrew Ebringer2, Joanne Baker2, Alyson Auliff2,
Gideon Kendino3, John Staley2, Derek Davis2, Nanhua Chen2,
Robin Gregory2, Karl Rieckmann2, Ken Lilley2, G. Dennis Shanks2,
Qin Cheng2, Michael T. O’Neil4
1
The University of Queensland, Brisbane, Queensland, Australia, 2Australian
Army Malaria Institute, Enoggera, Queensland, Australia, 3The Papua New
Guinea Defence Force, Port Moresby, Papua New Guinea, 4Walter Reed
Army Institute of Research, Silver Spring, MD, United States
193
T CELL RESPONSES TO MODIFIED PLASMODIUM FALCIPARUM
MSP119 ANTIGENS IN PEOPLE PREVIOUSLY EXPOSED TO NATURAL MALARIA INFECTION
Malaria - Immunology
Christian M. Okafor1, Chairat Uthaipibull2, Chiaka I. Anumudu3,
Yusuf O. Omosun4, Idowu Ayede5, Henrietta O. Awobode3,
Alexander B. Odaibo3, Jean Langhorne6, Anthony Holder6, Marita
Troye-Blomberg7, Mark Nwagwu3, Roseangela I. Nwuba3
188
SPECIFIC PLASMODIUM ELIMINATION DURING A SECOND
INFECTION IN CBA/CA MICE
1
FES Zaragoza, Universidad Nacional Autonoma de Mexico, Distrito Federal,
Mexico
Seattle Biomedical Research Institute, Seattle, WA, United States, 2Biotec,
Bangkok, Thailand, 3Cellular Parasitology Programme, University of Ibadan,
Ibadan, Nigeria, 4Bells University, Otta, Nigeria, 5Oni Memorial Hospital,
Ibadan, Nigeria, 6National Institute of Medical Research, NIMR, London,
United Kingdom, 7Wenner-Gren Institute, Stockholm University, Stockholm,
Sweden
(ACMCIP Abstract)
(ACMCIP Abstract)
Martha Legorreta-Herrera, Adriana Ramos-Avila,
Jannete R. Rodríguez-López, Marcela Ulloa-Martínez,
Osvaldo D. Castelan-Martínez
194
189
ANTIBODY RESPONSES TO THE MSP-1 COMPLEX PROTEINS IN
CEREBRAL MALARIA PATIENTS IN INDIA
ROLE OF COMPLEMENT AND COMPLEMENT REGULATORY
PROTEINS IN SEVERE ANEMIA CAUSED BY PLASMODIUM
CHABAUDI
Naomi W. Lucchi1, Jon Eric Tongren1, Vidhan Jain2, Avinash C.
Nagpal3, Christian W. Kauth4, Ute Woehlbier4, Hermann Bujard4,
Aditya P. Dash5, Jonathan K. Stiles6, Neeru Singh2, Venkatachalum
Udhayakumar1
Juliana V. Harris, Catherine N. Stracener, José A. Stoute
Uniformed Services University of the Health Sciences, Bethesda, MD, United
States
1
National Institute of Malaria Research, Regional Medicine Research Center
for Tribals, Indian Council of Medical Research, Jabalpur, India, 3Nethaji
Subash Chandra Bose Medical College, Jabalpur, India, 4Center of Molecular
Biology, Heidelberg University, Heidelberg, Germany, 5National Institute of
Malaria Research, Indian Council of Medical Research, New Delhi, India,
6
2
190
FCγ RECEPTOR POLYMORPHISMS IN GHANAIAN CHILDREN
WITH CLINICAL MALARIA
Anastasia R. Ocran
Noguchi Memorial Institute for Medical Research, Accra, Ghana
(ACMCIP Abstract)
73
Monday, November 5
1
Detailed Program
www.astmh.org
195
200
NATURAL RESISTANCE AGAINST SEVERE MALARIA IN
GHANAIAN CHILDREN DEPENDS ON TOLL-LIKE RECEPTORS
CALCITONIN GENE POLYMORPHISM (-624 T/C) IS ASSOCIATED
WITH SUSCEPTIBILITY TO MALARIAL ANEMIA IN INFANTS
AND YOUNG CHILDREN
John K. A. Tetteh1, Bamela Q. Goka2, George Obeng-Adjei2,
Catherine Jacquemot1, Fredrick N. Gyang3, Charlotte Behr4,
Bartholomew D. Akanmori1
Collins Ouma1, Gordon Awandare2, Tom Were1, Richard Otieno1,
Gregory Davenport2, Michael Otieno3, Alloys Orago3, John Vulule4,
John Michael Ong’echa1, Robert Ferrell2, Douglas Perkins2
1
Immunology Department, Noguchi Memorial Institute for Medical
Research, Accra, Ghana, 2Department of Child Health, Korle-Bu Teaching
Hospital, Accra, Ghana, 3Biochemistry Department, University of Ghana,
Accra, Ghana, 4Unité d’Immunologie Moléculaire des Parasites, Institut of
Pasteur, Paris, France
1
Pittsburgh, PA, United States, 3Kenyatta University, Nairobi, Kenya, 4KEMRI,
Kisumu, Kenya
(ACMCIP Abstract)
196
Malaria – Molecular Biology
MALARIA DEFERRED BLOOD DONATIONS: ARE THEY REALLY
A THREAT?
1
2
2
201
1
Megan Nguyen , Tami Goff , Joan Gibble , David Leiby
GENETIC DIVERSITY IN MSP-1 GENE OF PLASMODIUM FALCIPARUM IN AN ENDEMIC AREA OF CENTRAL INDIA
1
American Red Cross, Rockville, MD, United States, 2American Red Cross,
Baltimore, MD, United States
Praveen K. Bharti1, Md. Tauqeer Alam2, M.M. Shukla1, Y.D.
Sharma2, Neeru Singh1
(ACMCIP Abstract)
1
National Institute of Malaria Research, Jabalpur, India, 2Department of
Biotechnology, All India Institute of Medical Science, New Delhi, India
197
IMMUNOREGULATION IN MILD AND SEVERE P. FALCIPARUM
MALARIA
(ACMCIP Abstract)
202
Michael Walther1, Natalia Gomez-Escobar1, Susanne Deininger1,
Joseph Okebe1, Olivia Finney1, Davis Nwakanma1, Eleanor Riley2,
David Conway1
TOWARDS PLASMODIUM VIVAX ANTIGENIC GENES HAPMAP
OF INDIAN ISOLATES
1
MRC Laboratories Fajara, Banjul, Gambia, 2London School of Hygiene &
Tropical Medicine, London, United Kingdom
Surendra K. Prajapati1, Ramie H. Begum1, Mushahid A. Rizvi2,
Aditya P. Dash1, Hema Joshi1
1
National Institute of Malaria Research, New Delhi, India, 2Jamia Millia
Islamia University, New Delhi, India
(ACMCIP Abstract)
198
(ACMCIP Abstract)
CLINICAL AND IMMUNOLOGICAL MARKERS FOR THE
PROGNOSIS OF MALARIA IN GHANAIAN CHILDREN
1
2
203
2
William Ekloh , Bamela Q. Goka , George Obeng-Adjei ,
John K. A. Tetteh3, Sammy T. Sackey4, Charlotte Behr5,
Bartholomew D. Akanmori3
GENETIC DIVERSITY ASSOCIATED WITH VACCINE CANDIDATE
ANTIGENS IN PLASMODIUM FALCIPARUM AND P. VIVAX ISOLATES FROM THE AMAZON REGION OF PERU
1
University of Cape Coast, Immunology Department, Noguchi Memorial
Institute for Medical Research, Cape Coast, Accra, Ghana, 2Department
of Child Health, Korle-Bu Teaching Hospital, Accra, Ghana, 3Immunology
Department, Noguchi Memorial Institute for Medical Research, Legon,
Accra, Ghana, 4Biochemistry Department, University of Ghana, Legon,
Accra, Ghana, 5Unite d’ Immunologie Moleculaire des Parasite, Institute
of Pasteur, Paris, France
Stella M. Chenet1, David J. Bacon1, Ananias A. Escalante2,
OraLee H. Branch3
1
US Naval Medical Research Center Detachment, Lima, Peru, 2Arizona State
University, Tempe, AZ, United States, 3University of Alabama at Birmingham,
Birmingham, AL, United States
204
199
A SNP-BASED MOLECULAR BARCODE FOR P. FALCIPARUM
IDENTIFICATION AND TRACKING
B CELL ACTIVITY IN CHILDREN WITH SEVERE MALARIAL
ANEMIA
1
2
Rachel Daniels1, Sarah K. Volkman2, Dan Milner2,
Danny Park1, Ousmane Sarr3, Daouda Ndiaye3, Dyann F. Wirth2,
Roger C. Wiegand1
1
Jackson C. Korir , Ronald P. Taylor , John N. Waitumbi
1
Walter Reed Project/KEMRI, Kisumu, Kenya, 2Department of Biochemistry
and Molecular Genetics, University of Virginia School of Medicine,
1
Broad Institute of Harvard and MIT, Cambridge, MA, United States,
Harvard School of Public Health, Boston, MA, United States, 3Cheikh Anta
Diop University, Dakar, Senegal
2
(ACMCIP Abstract)
205
THE IMPACT OF DISSOCIATION ON TRANSPOSON-MEDIATED
DISEASE CONTROL STRATEGIES
John M. Marshall, Tom Chou
University of California at Los Angeles, Los Angeles, CA, United States
(ACMCIP Abstract)
74
206
www.astmh.org
210
HIGH GENETIC DIVERSITY OF PLASMODIUM FALCIPARUM
AND LOW COMPLEXITY OF INFECTION IN THE PERUVIAN
AMAZON
INVASION PHENOTYPES AND TRANSCRIPT PROFILES IN
GAMBIAN PLASMODIUM FALCIPARUM CLINICAL ISOLATES
Natalia Gomez-Escobar, Michael Walther, Alfred A. Ngwa, Joseph
Okebe, Davis Nwakanma, David Conway
Richard C. Delgado1, Dionicia Gamboa1, Katherine Torres1,
Tanilu Grande1, Alejandro Llanos1, Cesar Carcamo2, Umberto
D’Alessandro3
MRC Laboratories, Banjul, Gambia
(ACMCIP Abstract)
1
Institute of Tropical Medicine “Alexander von Humboldt” – Universidad
Peruana Cayetano Heredia, Lima, Peru, 2Universidad Peruana Cayetano
Heredia, Lima, Peru, 3Prince Leopold Institut of Tropical Medicine, AntwerpBelgium, Belgium
INVESTIGATION ON THE RELATIONSHIP BETWEEN
ERYTHROCYTE BINDING ANTIGEN 175 (EBA 175) GENOTYPES
OF PLASMODIUM FALCIPARUM AND CLINICAL MALARIA IN A
HYPERENDEMIC AREA OF GHANA
(ACMCIP Abstract)
207
PREVALENCE AND MOLECULAR BASIS OF α-THALASSAEMIA
IN A MALARIA ENDEMIC REGION OF VIETNAM
Beverly Egyir1, Ruth Ayanful1, Charles Brown1, Michael D.
Wilson1, Kwadwo Koram2
1
Parasitology Department, Noguchi Memorial Institute for Medical Research,
Accra, Ghana, 2Epidemiology Department, Noguchi Memorial Institute for
Medical Research, Accra, Ghana
N.Q. Nguyen1, S.P. O’Riordan1, QT Cao1, MT Dao1, TL Le2, QA Do2,
K. Miles3, A. Allen3, TH Vu1, HP Nguyen4, QH Nguyen5, SJ Dunstan1,
TE Peto6, TH Tran4, JJ Farrar1, JB Clegg3, DJ Weatherall3
Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho
Chi Minh City, Vietnam, 2Phuoc Long District Health Centre, Phuoc Long
District, Binh Phuoc Province, Vietnam, 3The Molecular Haematology
Division, Weatherall Institute of Molecular Medicine, Oxford, United
Kingdom, 4Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam, 5The
Institute of Malariology, Parasitology and Entomology, Ho Chi Minh City,
Vietnam, 6The Nuffield Department of Medicine, Oxford University, Oxford,
United Kingdom
(ACMCIP Abstract)
(ACMCIP Abstract)
Eng-Hong Lee
1
Malaria - Vaccines
212
COCCIDIOSIS CONTROL IN POULTRY WITH VACCINES OF FIELD
ISOLATES AS A MODEL OF EFFICACY, SUSTAINABILITY AND
AFFORDABILITY FOR THE CONTROL OF MALARIA
208
Vetech Laboratories Inc., Guelph, ON, Canada
213
DISRUPTION OF 2-CYS PEROXIREDOXIN TPX-1 GENE
IN PLASMODIUM BERGHEI HINDERS THE SPOROZOITE
DEVELOPMENT
PHASE 1 SAFETY AND IMMUNOGENICITY TRIAL OF BLOODSTAGE MALARIA VACCINES MSP142-C1/ALHYDROGEL WITH
AND WITHOUT THE ADDITION OF CPG 7909 IN US ADULTS
Shin-ichiro Kawazu1, Kazuhiko Yano2, Hitoshi Otsuki3,
Meiji Arai4, Kanako Komaki-Yasuda2, Takafumi Tsuboi5,
Motomi Torii3, Shigeyuki Kano2
Laura B. Martin1, Donna Shaffer2, Ruth D. Ellis1, Carole A. Long1,
Kazutoyo Miura1, David L. Narum1, Daming Zhu1, Gregory E.
Mullen1, Siddhartha Mahanty1, Elissa Malkin1, Louis H. Miller1, Allan
Saul1, Anna P. Durbin2
1
National Research Center for Protozoan Diseases, Obihiro University of
Agriculture and Veterinary Medicine, Hokkaido, Japan, 2Research Institute,
International Medical Center of Japan, Tokyo, Japan, 3Department of
Molecular Parasitology, Ehime University School of Medicine, Ehime, Japan,
4
Department of Parasitology and Tropical Public Health, School of Medicine,
University of Occupational and Environmental Health, Kitakyusyu, Japan,
5
Cell-Free Science and Technology Research Center, Ehime University,
Ehime, Japan
1
Malaria Vaccine Development Branch, National Institute of Allergy and
Infectious Diseases/National Institutes of Health, Rockville, MD, United
States, 2Center for Immunization Research, Johns Hopkins School of Public
Health, Washington, DC, United States
214
209
ANTIBODY-INDUCED PHAGOCYTOSIS OF P. FALCIPARUM
MEROZOITES BY NEUTROPHIL MEASURED WITH CHEMILUMINESCENCE OXIDATIVE BURSTS AS A RELEVANT FUNCTIONAL
ASSAY FOR CORRELATE OF PROTECTION AND MSP VACCINE
DEVELOPMENT
TRACING THE ORIGIN, MOLECULAR IDENTITY AND GENETIC
DIVERSITY OF THE PLASMODIUM FALCIPARUM FCR3/GAMBIA
FAMILY
Thavamani Rajapandi, Jianbing Mu, Xinzhuan Su, Timothy
Stedman
Ronald Perraut1, Charlotte Joos2, Laurence Marrama1, Hannah E
.J. Polson3, Sandra Corre2, Adama Tall2, Cheikh A. Sokhna4, Alioune
Dieye2, Shirley Longacre3
MR4/ATCC, Manassas, VA, United States
1
Institut Pasteur Guadeloupe, Abymes, Guadeloupe, 2Institut Pasteur Dakar,
Dakar, Senegal, 3Institut Pasteur, Paris, France, 4IRD, Dakar, Senegal
(ACMCIP Abstract)
75
Monday, November 5
211
Detailed Program
www.astmh.org
215
220
EVALUATION OF IMMUNOGLOBULIN PURIFICATION METHODS
AND THEIR EFFECTS ON IGS ANTIBODY SPECIFICITY
MINIATURIZED HIGH THROUGHPUT PLDH-BASED
PLASMODIUM FALCIPARUM GROWTH INHIBITION ASSAY FOR
LOW VOLUME SAMPLES
Ryan Mease1, Elizabeth H. Duncan1, John Waitumbi2, Elke
Bergmann-Leitner1, Evelina Angov1
Elke S. Bergmann-Leitner, Elizabeth H. Duncan, Michele D. Spring,
Evelina Angov
1
2
Kenya Medical Research Institute, Kisumu, Kenya
216
221
PLANS FOR CLINICAL TRIALS OF A METABOLICALLY
ACTIVE, NON-REPLICATING PLASMODIUM FALCIPARUM
SPOROZOITE VACCINE
HELMINTHIASIS AS A CONFOUNDING FACTOR IN HIV AND
MALARIA VACCINE TRIALS
Judith E. Epstein1, Kirsten E. Lyke2, Laurence Lemiale3, Maria S.
Reyes1, David Regis1, Francis Williams1, Jose Mendoza-Silveiras1,
Falgunee Parekh1, Kim Lee Sim4, Robert Edelman2, Thomas L.
Richie1, Stephen L. Hoffman5
University of Witwatersrand, Johannesburg, South Africa
Miles B. Markus
(ACMCIP Abstract)
222
1
Naval Medical Research Center, Silver Spring, MD, United States, 2Center
for Vaccine Development, University of Maryland, Baltimore, MD, United
States, 3PATH Malaria Vaccine Initiative, Bethesda, MD, United States,
4
Protein Potential LLC, Rockville, MD, United States, 5Sanaria Inc., Rockville,
MD, United States
EXPRESSION OF MSP3-MSP1 CHIMERIC PROTEIN AND
EVALUATION OF ITS IMMUNOGENICITY USING HUMAN
COMPATIBLE ADJUVANTS
Suman Mazumdar1, Asif Mohmmed1, Syed S. Yazdani1,
S. K. Jain2, Virander S. Chauhan1
217
1
International Centre for Genetic Engineering and Biotechnology, New Delhi,
India, 2Jamia Hamdard, New Delhi, India
DEVELOPMENT AND OPTIMIZATION OF A PLASMODIUM FALCIPARUM INHIBITION OF SPOROZOITE INVASION (ISI) ASSAY
Malaria – Vector Biology and Malaria Transmission
Brent L. House1, Xiaoyan Zou1, Joao C. Aguiar1, Patricia De La
Vega2, Thomas L. Richie1
223
1
Naval Medical Research Center, Silver Spring, MD, United States, 2Walter
OWNERSHIP AND USAGE OF ITNS IN NIGER AFTER
DISTRIBUTION DURING A NATIONWIDE INTEGRATED
CAMPAIGN
218
PRE-CLINICAL EVALUATION OF SAFETY AND IMMUNOGENICITY OF PLASMODIUM FALCIPARUM LSA1/AS01B WHEN
ADMINISTERED SEPARATELY OR CONCURRENTLY WITH
RTS,S/AS01B IN RHESUS PRIMATES
Julie I. Thwing1, Jodi Vanden Eng1, Marcel Lama2
1
World Health Organization, Harare, Zimbabwe
2
224
Sathit Pichyangkul1, Utaiwan Kum-Arb1, Kosol Yongvanitchit1,
Amporn Limsalakpetch1, Monthip Gettayacamin1, David E. Lanar2,
Lisa A. Ware2, V. A. Stewart2, D. Gray Heppner2, Pascal Mettens3,
Joe D. Cohen3, W. R. Ballou3, Mark M. Fukuda1
DICHLORODIPHENYLTRICHLOROETHANE (DDT) FOR INDOOR
RESIDUAL SPRAYING IN AFRICA: HOW CAN IT BE USED FOR
MALARIA CONTROL?
1
United States Army Medical Component-Armed Forces Research Institute of
the Medical Sciences, Bangkok, Thailand, 2Walter Reed Army Institute of
Research, Silver Spring, MD, United States, 3GlaxoSmithKline, Biologicals,
Rixensart, Belgium
Yesim Tozan1, Shobha Sadasivaiah2, Joel G. Breman3
1
Earth Institute, Columbia University, New York, New York; Fogarty
International Center, National Institutes of Health, Bethesda, MD, United
States, 2Weill Cornell Medical College of Cornell University, Cornell
University, New York, New York; Fogarty International Center, National
Institutes of Health, Bethesda, MD, United States, 3Fogarty International
Center, National Institutes of Health, Bethesda, MD, United States
219
DETECTING ANTIBODY FINE SPECIFICITIES TO P. FALCIPARUM
MSP1 SUBUNITS BY PARTICLE BASED FLOW CYTOMETRY IN
NAÏVE AND MALARIA EXPERIENCED POPULATIONS
VACCINATED WITH FMP1/AS02A
1
1
225
2
Michael McCasland , Afiya Brent-Kirk , Lorraine Soisson , José A.
Stoute1, Christian F. Ockenhouse1, John Waitumbi3, Bernhards
Ogutu3, Evelina Angov1
EXPRESSION OF WARP, A PUTATIVE TARGET FOR
TRANSMISSION BLOCKING VACCINES, DURING PLASMODIUM
GALLINACEUM SEXUAL DEVELOPMENT
1
United States Agency for International Development, Washington, DC,
United States, 3Kenya Medical Research Institute, Kisumu, Kenya
Armando M. Neto
2
FIOCRUZ/Instituto René Rachou, Belo Horizonte, Brazil
(ACMCIP Abstract)
76
226
231
DEVELOPMENT OF PLASMODIUM FALCIPARUM IN CULEX
MOSQUITOES
ANNOTATION AND EXPRESSION PROFILING OF PRESUMPTIVE
APOPTOSIS REGULATORY GENES IN THE YELLOW FEVER
MOSQUITO, AEDES AEGYPTI
Jen Hume, Tovi Lehmann
Bart Bryant1, Carol D. Blair2, Ken E. Olson2, Rollie Clem1
Molecular, Cellular, and Developmental Biology Program, Arthropod
Genomics Center, Division of Biology, Kansas State University, Manhattan,
KS, United States, 2Arthropod-Borne and Infectious Diseases Laboratory,
Department of Microbiology, Immunology, and Pathology, Colorado State
University, Fort Collins, CO, United States
COMMUNITY-BASED SURVEILLANCE OF MALARIA VECTORS
IN DAR ES SALAAM, TANZANIA
232
Prosper Chaki1, Nicodem Govella1, Yvonne Geissbühler2, Deo
Mtasiwa3, Marcel Tanner2, Steven Lindsay4, Khadija Kannady5,
Marcia Castro6, Ulrike Fillinger4, Gerry Killeen1
PREVALENCE OF INSECTICIDE RESISTANCE IN POPULATIONS
OF THE DENGUE VECTOR AEDES AEGYPTI IN THAILAND
1
Republic of Tanzania, 2Swiss Tropical Institute, Basel, Switzerland, 3Dar es
Salaam City Council, Dar es Salaam, United Republic of Tanzania, 4Durham
University, Durham, United Kingdom, 5Dar es Salaam Urban Malaria Control
Programme, Dar es Salaam, United Republic of Tanzania, 6Harvard
University, Boston, MA, United States
Shavanthi Rajatileka1, William C. Black IV2, Yuwadee Trongtorkit3,
Audrey Lenhart1, Chamnarn Apiwathnasorn3, Pradhya Somboon4,
Philip McCall1, Hilary Ranson1
1
Liverpool School of Tropical Medicine, Liverpool, United Kingdom,
Department of Microbiology, Pathology and Immunology, Colorado
State University, Fort Collins, CO, United States, 3Department of Medical
Entomology, Faculty of Tropical Medicine, University of Mahidol, Bangkok,
Thailand, 4Department of Parasitology, Faculty of Medicine, Chiang Mai
University, Chiang Mai, Thailand
2
228
COST-EFFECTIVENESS OF ADDING BEDNET DISTRIBUTION FOR
MALARIA PREVENTION TO ANTENATAL CLINICS
233
Sylvia I. Becker-Dreps1, Andrea K. Biddle1, Audrey E. Pettifor1,
Gertrude Musuamba2, David Nku Imbie3, Steven R. Meshnick1,
Frieda Behets1
RNA INTERFERENCE OF THE INSULIN RECEPTOR IN CULEX PIPIENS ARRESTS OVARIAN DEVELOPMENT AND SIMULATE DIAPAUSE
2
University of North Carolina, Chapel Hill, NC, United States, School of
Public Health, Kinshasa, Democratic Republic of the Congo, 3Salvation Army,
Kinshasa, Democratic Republic of the Congo
Cheolho Sim, David L. Denlinger
Department of Entomology, Ohio State University, Columbus, OH,
United States
229
COMPARISON OF A SIMPLE CHELEX PROCEDURE AGAINST
STANDARD SALT PROTOCOL FOR DNA EXTRACTION FROM
WILD ANOPHELES SPP.
234
Musapa Mulenga1, Mtawa Mkulama1, Sandra Chishimba1, Petrica
Rouse2, Douglas Norris2, Philip E. Thuma1, Sungano Mharakurwa1
TRANSLATIONAL REGULATION OF EARLY TRYPSIN SYNTHESIS
BY TARGET OF RAPAMYCIN IN THE MOSQUITO AEDES
AEGYPTI
1
The Malaria Institute at Macha, Choma, Zambia, 2Johns Hopkins Bloomberg
School of Public Health, Baltimore, MD, United States
Michelle C. Brandon, James E. Pennington, Anne-Sophie
Schillinger, Roger L. Miesfeld
University of Arizona, Tucson, AZ, United States
Mosquitoes – Biochemistry and Molecular Biology
235
230
FUNCTIONAL CHARACTERIZATION OF THE AEDES AEGYPTI
CARBOXYPEPTIDASE GENE FAMILY
MULTIPLE INSECTICIDE RESISTANCE MECHANISMS IN
ANOPHELES GAMBIAE AND CULEX QUINQUEFASCIATUS
FROM BENIN (WEST AFRICA) AND OPERATIONAL CHALLENGE
FOR MALARIA VECTOR CONTROL
Jun Isoe, Anisha Menezes, Michael A. Wells, Roger L. Miesfeld
236
Vincent Corbel1, Raphael N’Guessan2, Cécile Brengues1, Fabrice
Chandre3, Luc Djogbenou4, Thibaud Martin3, Martin Akogbeto4,
Jean-Marc Hougard3, Mark Rowland2
1
ADULT AEDES AEGYPTI MOSQUITOES CAN SYNTHESIZE UREA
USING AN AMPHIBIAN URIC ACID DEGRADATION PATHWAY
2
IRD, Montpellier, France, London School of Hygiene and Tropical Medicine,
London, United Kingdom, 3IRD, Cotonou, Benin, 4CREC, Cotonou, Benin
Patricia Y. Scaraffia, Guanhong Tang, Jun Isoe, Vicki H. Wysocki,
Michael A. Wells, Roger L. Miesfeld
77
Monday, November 5
1
227
1
www.astmh.org
Detailed Program
www.astmh.org
237
244
TRANSGENIC EXPRESSION OF A VARIANT BEE VENOM PHOSPHOLIPASE A2 IN AEDES FLUVIATILIS MOSQUITOES TOWARDS
PLASMODIUM GALLINACEUM DEVELOPMENT
OLFACTORY RESPONSIVENESS TO THE HOST ATTRACTANT
CARBON DIOXIDE IN DIAPAUSING AND NONDIAPAUSING
ADULTS OF CULEX PIPIENS
Flávia G. Rodrigues
Rebecca M. Robich, Alan J. Grant, Richard J. Pollack,
Andrew Spielman
Centro de Pesquisas René Rachou - CPqRR - FIOCRUZ, Belo Horizonte MG, Brazil
238
Mosquitoes – Vector Biology
ANTIBODY RESPONSE AGAINST SALIVA ANTIGENS FROM
MALARIA AND ARBOVIRUS VECTORS IN TRAVELERS IN TROPICAL AFRICA
245
MONITORING ITN EFFICACY AND INSECTICIDE RESISTANCE IN
MALARIA VECTORS IN TANZANIA
Lionel Almeras1, Eve Orlandi-Pradines1, Laure Denis de Senneville1,
Franck Remoué2, Claude Villard3, Kristell Penhoat1, Catherine
Bourgoin4, Didier Fontenille5, Frederic Pagés1, Bruno Pradines1,
Thierry Fusaï1, Christophe Rogier1
Manisha A. Kulkarni
HealthBridge, Ottawa, ON, Canada
246
1
Institut de Médecine Tropicale du Service de Santé des Armées, MarseilleArmees, France, 2Institut de Recherche pour le développement (IRD), UR24
Epidémiologie et Prévention Unit, Centre IRD de Hann, Dakar, Senegal,
3
Faculté de Pharmacie, Marseille, France, 4Ecologie des Systèmes Vectoriels,
Institut Pasteur, Paris, France, 5Institut de Recherche pour le développement
(IRD), UR16 caractérisation et contrôle des populations de vecteurs Unit,
Centre IRD, Montpellier, France
HABITAT-BASED LARVAL INTERVENTIONS: A NEW PERSPECTIVE FOR MALARIA CONTROL
Weidong Gu1, Jürg Utzinger2, Robert Novak1
1
University of Alabama at Birmingham, Birmingham, AL, United States,
Swiss Tropical Institute, Basel, Switzerland
2
239
247
IDENTIFICATION OF CDNAS ASSOCIATED WITH MEIOTIC
DRIVE IN AEDES AEGYPTI
DYNAMICS OF INTERPLAY BETWEEN AEDES AEGYPTI SALIVA
PROTEINS AND HOST IMMUNE RESPONSES
Dongyoung Shin, Lizhong Jin, David W. Severson
Saravanan Thangamani, Prafulla K. Chandra, Bronwen E.
Lambson, Stephen K. Wikel
Global Health and Infectious Diseases, Notre Dame, IN, United States
240
(ACMCIP Abstract)
REMOBILIZATION OF PIGGYBAC IN ANOPHELES GAMBIAE
248
Barbara F. Ngudiankama, Robert A. Harrell, Chana Aluvihare,
Dave A. O’Brochta
DIVERSITY OF CULICINE MOSQUITOES (DIPTERA: CULICIDAE)
IN AN AFRICAN RICE AGROSYSTEM, MWEA-KENYA
University of Maryland Biotechnology Institute, Rockville, MD, United States
Josephat I. Shililu1, Ephantus J. Muturi2, Joseph M. Mwangangi3,
Benjamin Jacob2, Charles M. Mbogo3, Weidong Gu2, John I.
Githure1, Robert J. Novak2
241
FIRST REPORT OF ACE.1 MUTATION IN ANOPHELES ARABIENSIS POPULATIONS FROM BURKINA FASO (WEST AFRICA)
1
ICIPE, Nairobi, Kenya, 2UAB, Birmingham, AL, United States, 3KEMRI, Kilifi,
Kenya
Kounbobr R. Dabiré
Centre Muraz/IRSS, Bobo-Dioulasso, Burkina Faso
249
242
POTENTIAL INCRIMINATION OF ANOPHELES
(NYSSORHYNCHUS) ALBIMANUS AND AN. (KERTESIA) NEIVAI
AS MALARIA VECTORS IN THE PACIFIC REGION OF COLOMBIA
THE ROLE OF THE INSULIN SIGNALING CASCADE AND THE
TGF-BETA SIGNALING PATHWAY IN ANTI-PARASITE DEFENSE
IN ANOPHELES GAMBIAE
Lina A. Gutiérrez1, Liliana Cordoba1, Nelson Naranjo1, Carlos
Muskus2, Shirley Luckhart3, Jan E. Conn4, Margarita M. Correa1
Ashley A. Horton, Cheick Coulibaly, Susan House, Shirley Luckhart
1
Grupo Microbiologia Molecular, Escuela de Microbiologia, Universidad de
Antioquia, Medellin, Colombia, 2Programa de Estudio y Control de
Enfermedades Tropicales-PECET, Fac de Medicina, Universidad de Antioquia,
Medellin, Colombia, 3Department of Medical Microbiology and Immunology,
University of California, Davis, CA, United States, 4Griffin Laboratory.
Wadsworth Center, New York State Department of Health, Albany, NY,
United States
University of California Davis, Davis, CA, United States
243
THE STAT PATHWAY LIMITS PLASMODIUM INFECTION
IN AN. GAMBIAE
Carolina Barillas-Mury, Lalita Gupta, Alvaro Molina-Cruz,
Sanjeev Kumar
78
250
www.astmh.org
258
EFFICACY OF CDC LIGHT TRAP SAMPLING TO MONITOR THE
HOST-SEEKING BEHAVIOR OF ANOPHELES ARABIENSIS IN
SOUTHERN ZAMBIA
RISK FACTORS FOR HOUSE-ENTRY BY MALARIA VECTORS IN
A RURAL TOWN AND SATELLITE VILLAGES IN THE GAMBIA
Christen M. Fornadel1, Rebekah J. Kent2, Douglas E. Norris1
University of Durham, Durham City, United Kingdom
Matt Kirby, Steve W. Lindsay
1
Johns Hopkins Bloomberg School of Public Health, Baltimore, MD,
United States, 2Centers for Disease Control and Prevention, Fort Collins,
CO, United States
EVALUATION OF THE RELATIONSHIPS BETWEEN HUMAN
ACTIVITIES AND CONTAINER BREEDING AEDES IN URBAN
WEST AFRICA USING A GEOGRAPHIC SAMPLING STRATEGY
251
β1 REGULATION OF THE ANTI-MALARIAL
HUMAN TGF-β
RESPONSE IN MOSQUITOES
University of California Davis, Davis, CA, United States
Emily S. Jentes1, Joseph Keating1, Christopher Swalm1, Camille
Edwards1, Frederique Jacquerioz1, Noumouny Sacko2, Kerfallah
Kourouma2, Jean Sagno2, Janet Rice1, Mamadi Coulibaly2, Dawn
Wesson1, Daniel G. Bausch1
(ACMCIP Abstract)
1
Tulane University, New Orleans, LA, United States, 2International Center for
Research on Tropical Infections in Guinea, N’Zérékoré, Guinea
Win Surachetpong, Naresh Singh, Shirley Luckhart
252
260
LOCATION, LOCATION, LOCATION — DISTANCES OF BREEDING WATER TO HUMAN HABITATIONS ARE AN IMPORTANT
INDICATOR FOR DESIGNING TARGETED INTERVENTIONS OF
HABITAT MANAGEMENT
CHARACTERIZING SPECIES DIVERSITY OF VECTORS IMPLICATED IN NON-TRADITIONAL EEE TRANSMISSION IN TENNESSEE
Sudeshna Mukherjee1, Beth Huddleston1, Erin Moody2, Kenneth
Lewockzo2, Ron Wilson3, John Dunn1, Tim F. Jones1, Abelardo C.
Moncayo1
Weidong Gu, Robert Novak
Department of Medicine, University of Alabama, Birmingham, Birmingham,
AL, United States
1
Tennessee Department of Health, Nashville, TN, United States, 2Union
University, Jackson, TN, United States, 3Tennessee Department of
Agriculture, Nashville, TN, United States
253
261
THE ROLE OF FLIGHT TONE CHARACTERISTICS ON MATE
SELECTION OF THE YELLOW FEVER MOSQUITO AEDES
AEGYPTI
PARTICIPATORY MAPPING OF TARGET AREAS TO
ENABLE OPERATIONAL LARVAL SOURCE MANAGEMENT
TO SUPPRESS MALARIA VECTOR MOSQUITOES IN DAR
ES SALAAM, TANZANIA
Lauren J. Cator
Stefan Dongus1, Dickson Nyika2, Khadija Kannady3, Deo
Mtasiwa3, Hassan Mshinda2, Ulrike Fillinger4, Axel W. Drescher5,
Marcel Tanner1, Marcia C. Castro6, Gerry F. Killeen4
254
COMPARATIVE RESPONSE OF MOSQUITOES TO INSECTICIDAL
TOXIC BAITS
1
Swiss Tropical Institute, Basel, Switzerland, 2Ifakara Health Research and
Development Centre, Dar es Salaam, United Republic of Tanzania, 3City
Medical Office of Health, Dar es Salaam, United Republic of Tanzania,
4
Durham University, Institute of Ecosystems Science, Durham, United
Kingdom, 5University of Freiburg, Department of Physical Geography,
Freiburg, Germany, 6Harvard School of Public Health, Boston, MA,
United States
Sandra A. Allan
USDA/ARS/CMAVE, Gainesville, FL, United States
Mosquitoes – Vector Biology - Epidemiology
256
262
SPATIAL EXPLORATION OF HUMAN WNV DISEASE INCIDENCE
IN THE NORTHEASTERN UNITED STATES
UNDERSTANDING THE SPATIAL AND TEMPORAL DISTRIBUTION OF POTENTIAL MOSQUITO VECTORS OF RIFT VALLEY
FEVER IN THE U.S.
Heidi E. Brown, James Childs, Maria A. Diuk-Wasser, Durland Fish
Seth C. Britch, Kenneth J. Linthicum
257
USDA-ARS/CMAVE, Gainesville, FL, United States
REGIONAL COMPARISONS OF THE HOST FEEDING PATTERNS
OF MAJOR VECTORS OF WEST NILE AND EASTERN EQUINE
ENCEPHALITIS VIRUSES IN THE U.S.
263
ISOLATIONS OF JAMESTOWN CANYON VIRUS
(BUNYAVIRIDAE: ORTHOBUNYAVIRUS) FROM FIELD-COLLECTED MOSQUITOES (DIPTERA: CULICIDAE) IN CONNECTICUT,
USA: A TEN-YEAR ANALYSIS, 1997-2006
Goudarz Molaei, Theodore G. Andreadis, Philip M. Armstrong
The Connecticut Argicultural Experiment Station, New Haven, CT,
United States
Theodore G. Andreadis, John F. Anderson, Philip M. Armstrong
The Connecticut Agricultural Experiment Station, New Haven, CT,
United States
79
Monday, November 5
259
Detailed Program
www.astmh.org
264
269
THE USE OF EMPIRICAL MODE DECOMPOSITION FOR THE
STUDY OF THE TRANSMISSION OF DENGUE HEMORRHAGIC
FEVER IN THAILAND
1
2
ANTIPARASITIC EVALUATION OF HYBRIDS OF BENZIMIDAZOLE
DERIVATIVES AND 2-AMINO-5-NITROTHIAZOLE
Francisco Hernández-Luis1, Cecilia Padierna-Mota1, Alicia
Hernández-Campos1, Rafael Castillo1, Benjamina Nogueda-Torres2,
Adrián Márquez-Navarro2, Gustavo Erasmo Ruiz-Espinoza2, Israel
Velazquez-Martínez1, Lilián Yépez-Mulia3
1
Arthur Getis , Jared Aldstadt , Kristopher Kuzera ,
Thomas W. Scott3
1
San Diego State University, San Diego, CA, United States, 2University at
Buffalo, Buffalo, NY, United States, 3University of California, Davis, Davis,
CA, United States
1
Departamento de Farmacia, Facultad de Química, Universidad Nacional
Autónoma de México, México D.F., Mexico, 2Escuela Nacional de Ciencias
Biológicas, Instituto Politécnico Nacional, México D.F., Mexico, 3Unidad de
Investigación Médica en Enfermedades Infecciosas y Parasitarias, Centro
Médico Nacional IMSS-Siglo XXI, México D.F., Mexico
265
A NEW CLIMATE BASED MODEL FOR FORECASTING WEST
NILE MOSQUITO VECTOR POPULATION ABUNDANCE AND
HUMAN RISK
270
SYNTHESIS AND ANTIPROTOZOAL ACTIVITY OF NOVEL 1METHYLBENZIMIDAZOLE DERIVATIVES
Laura C. Harrington, Hongfei Gong, Arthur DeGaetano
Rafael Castillo1, Sergio Rodríguez-Morales1, David Valdez-Padilla1,
Alicia Hernández-Campos1, Francisco Hernández-Luis1,
Lilian Yépez-Mulia2
Protozoa – Ameba/Giardia
1
Universidad Nacional Autónoma de México, México, D.F., Mexico, 2Unidad
de Investigaciones Médicas y Parasitarias, IMSS, Mexico, D.F., Mexico
266
GIARDIA DOG GENOTYPES IN URBAN SETTINGS OF PERU AND
THE UNITED STATES: ZOONOTIC TRANSMISSION POTENTIAL?
271
Nina Castro1, Margarethe Cooper1, Kathryn Lancaster1, Kathryn
Miller1, Vitaliano Cama2, Robert Gilman3, Charles Sterling1
INACTIVATION EFFECT AND MOLECULAR DOCKING STUDIES
OF BENZIMIDAZOLE DERIVATIVES AGAINST
TRIOSEPHOSPHATE ISOMERASE FROM ENTAMOEBA HISTOLYTICA AND CORRELATION WITH IN VITRO ACTIVITY
1
University of Arizona, Tucson, AZ, United States, 2Centers for Disease
Control and Prevention, Atlanta, GA, United States, 3Johns Hopkins
University, Baltimore, MD, United States
Fabian Lopez-Vallejo1, José Luis Medina-Franco1, Alicia
Hernández-Campos1, Sergio Rodríguez-Morales1, Luis Tellez1, Lilián
Yépez-Mulia2, D. Alejandro Fernández-Velasco1, Rafael Castillo1
(ACMCIP Abstract)
267
1
Universidad Nacional Autónoma de México, Ciudad de México, Mexico,
Unidad de Investigación Médica en Enfermedades Infecciosas y Parasitarias,
Centro Médico Nacional Siglo XXI, IMSS, Ciudad de México, Mexico
2
MOLECULAR, BIOCHEMICAL AND PATHOLOGIC CHARACTERIZATION OF ACANTHAMOEBA CASTELLANI IRON- SUPEROXIDE
DISMUTASE (FE-SOD)
272
Jung-Yeon Kim1, Mi-Hyun Park1, Byung-Kook Na2, Hae-Won
Yang1, Jung-Won Ju1, Hyeng-Il Cheun1, Pyo-Yeon Cho1, Young-Hee
Lee1, Tong-Soo Kim1
ANTIPROTOZOAL ACTIVITY OF NOVEL BENZIMIDAZOLE
DERIVATIVES
1
Division of Malaria and Parasitic Diseases, National Institute of Health,
KCDC, Seoul, Republic of Korea, 2Kyungsang University, Jin-ju, Republic
of Korea
Maria A. Hernández-Campos1, Sonia Aguilar-González1, Lilián
Yépez-Mulia2, Francisco Hernández-Luis1, Rafael Castillo1
1
Universidad Nacional Autónoma de México, Ciudad de México, Mexico,
Unidad de Investigación Médica en Enfermedades Infecciosas y Parasitarias,
Centro Médico Nacional Siglo XXI, IMSS, Ciudad de México, Mexico
2
268
USE OF MULTIPLEX REAL-TIME PCR TO IMPROVE THE DETECTION OF GIARDIA LAMBLIA AND CRYPTOSPORIDIUM
PARVUM IN HUMAN FAECAL SAMPLES
273
PROTEOMICAL EVALUATION OF NOVEL GIARDICIDAL
BENZIMIDAZOLE DERIVATIVES
Wayne Melrose1, Karen Johnson2, Graeme Nimmo3
1
James Cook University, Townsville, Australia, 2Princess Alexandra Hospital,
Brisbane, Australia, 3University of Queensland, Townsville, Australia
Javier R. Ambrosio1, Carlos A. Mendez-Cuesta1,
Maria A. Dea-Ayuela2, Olivia A. Reynoso-Ducoing1, Liliana
Velázquez-Márquez1, Rafael Castillo-Bocanegra1, Francisco
Hernández-Luis1, Alicia Hernández-Campos1, Lilian Yépez-Mulia3,
Francisco Bolás-Fernández2
(ACMCIP Abstract)
1
Universidad Nacional Autónoma de México, Mexico City, Mexico,
Universidad Complutense de Madrid, School of Pharmacy, Spain, 3Instituto
Mexicano del Seguro Social CMN Siglo XXI, UIMEIP, Hosp. Ped., Mexico
2
(ACMCIP Abstract)
80
Viruses - Other
www.astmh.org
KS, United States, 2Arthropod-Borne and Infectious Diseases Laboratory,
Department of Microbiology, Immunology, and Pathology, Colorado State
University, Fort Collins, CO, United States
274
280
MONITORING MICROARRAY-BASED GENE EXPRESSION
PROFILE CHANGES IN VACCINIA VIRUS
THE CARRIER RATE OF NEWCASTLE DISEASE VIRUS IN
PIGEONS IN OWERRI AREA OF IMO STATE, NIGERIA
Irshad M. Sulaiman1, Robin Scarborough2, Keith Levert1, John
Osborne2, Nikhat Sulaiman1, Dhwani Govil1, Kevin Tang2, Scott
Sammons2, Brian Holloway2, Joseph Esposito2, Robert Wohlhueter2
Alex D. Acholonu1, A. U. Apara2
Alcorn State University, Alcorn State, MS, United States, 2Imo State
University, Owerri, Nigeria
Centers for Disease Control and
Prevention/CCID/NCPDCID/DSR/BCFB/Atlanta Research and Education
Foundation, Atlanta, GA, United States, 2Centers for Disease Control and
Prevention/CCID/NCPDCID/DSR/BCFB, Atlanta, GA, United States
281
NIPAH OUTBREAK WITH PERSON-TO-PERSON TRANSMISSION
IN BANGLADESH, 2007
275
IDENTIFICATION OF NON POLIO ENTEROVIRUSES ISOLATED
FROM SELECTED AFP STOOL SAMPLES IN THE GHANA POLIO
REGIONAL REFERENCE LABORATORY: IMPLICATION FOR
CAUSATIVE AGENTS TO AFP OTHER THAN POLIO
Nusrat Homira1, Mahmudur Rahman2, M. J. Hossain1, Imtiaz A.
Chowdhury2, Rebeca Sultana1, Rasheda Khan1, Be-Nazir Ahmed2,
Shakila Banu1, Kamrun Nahar2, Goutam Poddar1, Emily Gurley1,
James A. Comer3, Pierre E. Rollin3, Paul Rota3, Thomas G. Ksiazek3,
Stephen Luby1
Miriam A. Sagoe, Jacob S. Barnor
1
ICDDRB, Dhaka, Bangladesh, 2Institute for Epidemiology Disease Control
and Research, Dhaka, Bangladesh, 3Centers for Disease Control and
Prevention, Atlanta, GA, United States
Noguchi Memorial Institute for Medical Research, Accra, Ghana
276
282
QUANTITATIVE PCR ASSAY FOR THE DETECTION AND
DIFFERENTIATION OF MONKEYPOX VIRUS FROM OTHER
ORTHOPOXVIRUSES
GENETIC RELATIONSHIPS OF JAMESTOWN CANYON VIRUSES
INFECTING CONNECTICUT MOSQUITOES
David N. Shahan, Sydney Lee
Philip M. Armstrong, Theodore G. Andreadis
ATCC/BEI Resources, Manassas, VA, United States
The Connecticut Agricultural Experiment Station, New Haven, CT,
United States
(ACMCIP Abstract)
277
283
ELEVATED TESTOSTERONE AND REDUCED 5-HIAA CONCENTRATIONS ARE ASSOCIATED WITH WOUNDING AND HANTAVIRUS INFECTION IN MALE NORWAY RATS
IMMUNOLOGICAL RESPONSE AND PROVIRAL LOAD AS
FACTORS INFLUENCING DISEASE EXPRESSION IN HTLV-1
Edgar M. Carvalho, Marcia C. Nascimento, Neviton Castro, Andre
Luiz A. Muniz, Amelia R. de Jesus, Aurelia F. Porto, Isadora Siqueira,
Silvane B. Santos
Judith Easterbrook1, Jenifer Kaplan1, Gregory Glass1, Mikhail
Pletnikov2, Sabra Klein1
1
United States, 2Johns Hopkins University School of Medicine, Baltimore,
MD, United States
Federal University of Bahia, Salvador, Brazil
Trematodes - Other
278
284
COMMON MARMOSETS (CALLITHRIX JACCHUS) AS A
NON-HUMAN PRIMATE MODEL FOR EASTERN EQUINE
ENCEPHALITIS
REFERENCE AND DEVELOPMENTALLY EXPRESSED GENES OF
CLONORCHIS SINENSIS QUANTIFIED BY REAL-TIME PCR
Won Gi Yoo1, Tae Im Kim1, Shunyu Li1, Sung-Jong Hong1, Pyo Yun
Cho2, Tong Soo Kim2
A.P. Adams1, N.C. Arrigo1, J.F. Aronson1, S.D. Tardif2, J.L.
Patterson3, K.M. Brasky2, C.E. Johnson3, M. de la Garza2, R.
Carrion, Jr.3, S.C. Weaver1
1
Chung-Ang University, Seoul, Republic of Korea, 2NIH Korea, Seoul,
Republic of Korea
1
Department of Pathology, University of Texas Medical Branch, Galveston,
TX, United States, 2Southwest National Primate Research Center, Southwest
Foundation for Biomedical Research, San Antonio, TX, United States,
3
Department of Virology and Immunology, Southwest Foundation for
Biomedical Research, San Antonio, TX, United States
285
RELATIONSHIP OF SPECIFIC FIBRINOGEN-RELATED PROTEINS
TO ACQUIRED RESISTANCE IN THE SNAIL BIOMPHALARIA
GLABRATA
279
Barbara A. Stout, Si-Ming Zhang, Coen M. Adema, Eric S. Loker
RECOMBINANT SINDBIS VIRUSES THAT REGULATE APOPTOSIS
IN THE C6/36 AEDES ALBOPICTUS CELL LINE
University of New Mexico, Albuquerque, NM, United States
(ACMCIP Abstract)
Hua Wang1, Carol D. Blair2, Ken E. Olson2, Rollie J. Clem1
1
Molecular, Cellular, and Developmental Biology Program, Arthropod
Genomics Center, Division of Biology, Kansas State University, Manhattan,
81
Monday, November 5
1
1
Detailed Program
www.astmh.org
Trematodes - Schistosomiasis
291
286
AN OUTBREAK OF SCHISTOSOMIASIS MANSONICA:
IMMUNOLOGICAL STATUS OF ACUTE AND INTESTINAL CASES
IN AN ENDEMIC REGION OF BRAZIL
RNA SILENCING IN SCHISTOSOMA MANSONI
Mariana Simoes1, Appolinaire Djikeng2, Gustavo Cerqueira3, Philip
LoVerde4, Guilherme Oliveira1, Najib El-Sayed5
Elizabeth C. Moreno1, Lucia A. Fraga2, Luiz Cosme Cotta
Malaquias2, Claudia Carvalho-Queiroz3, Denise Lemos4, Andrea
Teixeira4, Olindo A. Martins-Filho4, Rodrigo Correa-Oliveira4, Philip
LoVerde3, Giovanni Gazzinelli4
1
Fundacao Oswaldo Cruz, Centro de pesquisas Rene Rachou, Belo
Horizonte, Brazil, 2The Institute for Genomic Research, Rockville, MD,
United States, 3Universidade Federal de Minas Gerais, Belo Horizonte, Brazil,
4
United States, 5University of Maryland, College Park, MD, United States
1
Fundação Nacional de Saúde, Universidade Federal de Minas Gerais, Belo
Horizonte, Minas Gerais, Brazil, 2Universidade Vale do Rio Doce, Gov.
Valadares, Minas Gerais, Brazil, 3University of New York at Buffalo, Buffalo,
NY, United States, 4Centro de Pesquisas Rene Rachou, Belo Horizonte, Minas
Gerais, Brazil
287
GENE EXPRESSIONAL CHANGES DURING THE SCHISTOSOMA
JAPONICUM LIFECYCLE
292
Geoffrey Gobert
NOVEL DRUGS FOR SCHISTOSOMIASIS: ESTABLISHMENT OF A
MEDIUM-THROUGHPUT WHOLE-ORGANISM SCREEN AT
UNIVERSITY OF CALIFORNIA AT SAN FRANCISCO
(ACMCIP Abstract)
Conor R. Caffrey1, Debbie S. Ruelas1, Maha-Hamadien Abdulla1,
K.C. Lim1, Brian Wolff2, Adam Renslo2, Janice Williams2,
James H. McKerrow1
288
CHARACTERIZATION OF A P-GLYCOPROTEIN HOMOLOG IN
SCHISTOSOMA MANSONI
1
Sandler Center for Basic Research in Parasitic Diseases, University of
California at San Francisco, CA, United States, 2Small Molecule Discovery
Center, University of California at San Francisco, CA, United States
Shanta M. Messerli, William Morgan, Stefani Spranger,
Robert M. Greenberg
293
289
CYTOKINE EXPRESSION AND IMMUNOGLOBULIN ISOTYPE
PRODUCTION IN PRE-PATENT SCHISTOSOMA MANSONI
INFECTION
TRANSGENESIS OF SCHISTOSOMA MANSONI MEDIATED BY
MURINE LEUKEMIA VIRUS
Lucia A. Fraga1, Anna Tocheva2, Erika Lamb2, Mazen Makarem2,
Connor R. Caffrey3, Stephen S. Davies2
Kristine J. Kines1, Maria E. Morales1, Victoria H. Mann1,
Geoffrey N. Gobert2, Paul J. Brindley1
1
Uniformed Services University of the Health Sciences, Universidade Vale do
Rio Doce, SESMG-DRS-GV, Gov. Valadares, Minas Gerais, Brazil, 2Uniformed
Services University of the Health Sciences, Bethesda, MD, United States,
3
University of California San Francisco, San Francisco, CA, United States
1
Tulane University, New Orleans, LA, United States, 2Queensland Institute
of Medical Research, Brisbane, Australia
(ACMCIP Abstract)
290
294
A CLUSTER-RANDOMISED BOVINE INTERVENTION TRIAL
AGAINST S. JAPONICUM IN THE PEOPLES’ REPUBLIC OF CHINA
COMPARATIVE ANALYZE BIOMPHALARIA AMAZONICA AND
B. COUSINI IN RELATION TO OTHER SPECIES OF THE GENUS,
USING MORPHOLOGICAL AND MOLECULAR DATA
Darren J. Gray1, Gail M. Williams1, Yuesheng Li2, Honggen Chen3,
Robert S. Li1, Simon J. Forsyth1, Adrian G. Barnett1, Jiagang Guo4,
Zheng Feng4, Donald P. McManus2
Tatiana M. Teodoro, Roberta L. Caldeira, Omar S. Carvalho
Centro de Pesquisas René Rachou/Fiocruz, Belo Horizonte, MG, Brazil
1
School of Population Health, The University of Queensland, Brisbane,
Australia, 2Australian Centre for International and Tropical Health and
Nutrition, The University of Queensland and The Queensland Institute of
Medical Research, Brisbane, Australia, 3Jiangxi Provincial Institute of Parasitic
Diseases, Nanchang, China, 4Institute of Parasitic Diseases, Chinese Centre
for Disease Control and Prevention, Shanghai, China
(ACMCIP Abstract)
295
MOLECULAR AND BIOCHEMICAL CHARACERIZATION OF
SCHISTOSOMA MANSONI PKA: A POTENTIAL NEW DRUG
TARGET
Brett E. Swierczewski, Stephen Davies
United States
(ACMCIP Abstract)
82
296
www.astmh.org
CHAIR
Anne McCarthy
PREPARATION OF NOVEL VACCINE CANDIDATES AGAINST
SCHISTOSOMA MANSONI
Erica Waite1, Rachel Curwen2, Gary Dillon3, Alan Wilson2, Tom
Kariuki4, Ronald Blanton1, Christopher L King1
12:15 p.m.
REFUGEE HEALTH IN THE UNITED STATES: RECENT
EPIDEMIOLOGY AND STRATEGIES FOR OPTIMIZING HEALTH
1
of York, Heslington, United Kingdom, 3University of York, Heslington,
United Kingdom, 4Institute of Primate Research, Karen, Kenya
David Boulware
12:35 p.m.
INVESTIGATING THE SOURCE OF IL-10 EARLY IN SCHISTOSOMIASIS INFECTION
WHAT’S UP NORTH? CANADIAN CLINICAL PREVENTIVE
HEALTH CARE GUIDELINES FOR NEWLY ARRIVING
IMMIGRANTS AND REFUGEES
Christine E. Banfield, Stephen J. Davies
United States
Christina A. Greenaway
SMBD Jewish General Hospital, Montreal, QC, Canada
298
PROTEOMIC ANALYSIS OF EXCRETORY-SECRETORY PROTEINS
RELEASED DURING IN VITRO SCHISTOSOMA MANSONI
MIRACIDIUM-TO-SPOROCYST TRANSFORMATION
12:55 p.m.
Xiao-Jun Wu, James F. Brown, Mengzi Zhang, Timothy P. Yoshino
Mary E. Wilson
University of Wisconsin-Madison, Madison, WI, United States
Harvard University, Washington, DC, United States
HOW DO MIGRATION AND INTERNATIONAL TRAVEL IMPACT
ON HEALTH?
(ACMCIP Abstract)
Mid-Day Session 28
299
ANTI-TREMATODE PARASITE RESPONSES OF THE SNAIL
BIOMPHALARIA GLABRATA: ARCHITECTURE OF FREP LOCI
Chronic Conditions Don’t Take Vacations: How to
Prepare Travelers with Chronic Conditions
Cheng Man Lun, Teresa M. Madrid, Ben Hanelt, Coenraad M.
Adema
Salon CD
(ACMCIP Abstract)
This symposium will address chronic conditions in travelers. Over 99 million
people have chronic conditions such as diabetes, hypertension and heart
disease. Many of these people will be traveling for business and/or pleasure
and need to adapt to time zones, different diets and physical activities. The
baby boomers are also getting older and traveling in great numbers. The
speakers will discuss strategies to prepare the traveler with one or more
chronic conditions.
Poster Session A ACMCIP Abstracts – Molecular,
Cellular and Immunoparasitology
57, 61, 69, 133, 136, 137, 140, 141, 145, 146, 147, 148, 149,
150, 151, 152, 154, 157, 158, 162, 163, 164, 176, 188, 191,
193, 194, 196, 197, 199, 200, 201, 22, 25, 26, 27, 210, 211,
214, 221, 225, 247, 251, 266, 268, 273, 276, 285, 287, 289,
294, 295, 298, 299
CHAIR
Pamela Allweiss
Christie Reed
Mid-Day Session 27
12:15 p.m.
Migrants to North America: Optimizing the Health of
High-Risk Migrants
A LITTLE SUGAR GOES A LONG WAY: TRAVELLING
WITH DIABETES
Salon AB
Pamela Allweiss
Refugees to North America represent a population with potential for significant tropical diseases. This session will review risks for recent refugee groups
to the United States and Canada, including screening prior to travel and on
after arrival. Pre-treatment strategies for common tropical diseases and a
novel approach at control of endemic diseases in source countries of
migrants will be presented.
12:40 p.m.
CHRONIC CONDITIONS DON’T TAKE VACATIONS: HOW TO
PREPARE PEOPLE WITH CHRONIC CONDTIONS FOR TRAVEL
Christie Reed
83
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University of Minnesota, Minneapolis, MN, United States
297
www.astmh.org
Detailed Program
1:05 p.m.
12:35 p.m.
CAREER OPPORTUNITIES IN THE FOUNDATIION WORLD
AND BEYOND
Regina Rabinovich
Director, Infectious Diseases Program
Mid-Day Session 29
Career Pathways in Global Health
Salon H
12:40 p.m.
CAREER OPPORTUNITIES IN GLOBAL HEALTH AND
ASTMH’S ROLE IN PROMOTING TRAINING AND ENTRY
INTO CAREER TRACKS
Financial investment in global health is expanding rapidly, both from public
and private sectors. With this expansion, career opportunities in global
health are growing commensurately. Many of these career opportunities
offer a challenging mix of science, epidemiology and program development
opportunities, based both in the United States and internationally. Many of
these career pathways are in organizations and settings that have not been a
focus of ASTMH members or constituencies, yet would naturally value the
perspectives and competencies of many students and trainees affiliated with
the Society. This session will bring together representative leaders and
spokespersons who have had varied careers in global health to speak review
their perspectives on career opportunities and share ideas on preparation and
entry into these pathways. The moderators will summarize the key points
and action steps, to enhance the society support for global health careers.
Panel Discussion
Mid-Day Session 30
Modern Multi-Modality Imaging of Tropical Diseases
Salon KL
Modern multi-modality imaging, including CT, MRI, ultrasound and general
radiology can contribute greatly to the diagnosis of over 70 tropical diseases.
A light lunch will be provided.
Speaker
Maurice Merrick Reeder
CHAIR
American College of Radiology, Potomac, MD, United States
Sarah Volkman
Mid-Day Session 31
Chagas: A Hidden Affliction
Franklin 1
12:15 p.m.
Monday, November 5, 2007 12:15 p.m. - 2 p.m.
THE NGO WORLD AND GLOBAL HEALTH
Scott Jackson
Vice-President for External Relations
Filmed in Argentina, the United States and Europe, this documentary gives a
voice to those suffering from Chagas, and to those working to find a cure
to this disease that affects about 20 million people worldwide, but is practically unknown to the general public.
PATH, Seattle, WA, United States
12:20 p.m.
CHAIR
CAREERS IN THE UNITED NATIONS SYSTEM
Melanie Renshaw
Senior Health Advisor (Malaria)
Rick L. Tarleton
UNICEF, New York, NY, United States
PRODUCER
Ricardo Preve
12:25 p.m.
Ricardo Preve Films LLC, Buenos Aires, Argentina
ACADEMIC MEDICINE BRIDGING TO TRAINING AND MEDICAL
RESEARCH GLOBALLY
Michele Barry
Professor of Medicine and Global Health
Mid-Day Session 32
Preparation and Review of Scientific Manuscripts for
the American Journal of Tropical Medicine & Hygiene
12:30 p.m.
Franklin 2
BREAKING INTO A GLOBAL HEALTH CAREER
Nadia Sam-Agudu
Pediatric Infectious Disease Fellow
This symposium is aimed at trainees and others interested in understanding
better how manuscripts are reviewed, edited and processed by the society’s
journal. Pointers on preparation and review of manuscripts will be stressed.
The following topics will be covered: 1) Why publish your work in our society’s journal; 2) Why and where to publish, i.e. selection of the “right” journal for your work; 3) Examples of a paper in progress; how to prepare and
how to write a good paper; 4) The submission and review processes and
University of Minnesota, Farmington, MN, United States
84
www.astmh.org
Meet the Professors 32A
how they work; 5) How to properly review a paper; 6) How to respond to
reviewer comments; and 6) The publication process: what happens after
your paper is accepted.
Meet the Professors B: Enigmatic and Teaching Cases
CHAIR
Franklin 3/4
James Kazura
A panel of professors will each present one clinical case of a tropical disease
specific to a particular region that they have found a challenge to manage
or diagnose. If there is time, participants may be able to present enigmatic
cases for the audience and panel to consider. An open discussion will be
encouraged, with audience participation.
Cathi Siegel
12:15 p.m.
WHY SELECT THE AMERICAN JOURNAL OF TROPICAL
MEDICINE AND HYGIENE (AJTMH) FOR YOUR PAPER:
SELECTING THE RIGHT JOURNAL FOR YOUR WORK
CHAIR
Anne McCarthy
James Kazura
PANELISTS
David O. Freedman
12:30 p.m.
MANUSCRIPT PROCESSING AT AJTMH
J. Dick MacLean
Cathi Siegel
McGill University Center for Tropical Diseases, Montreal, QC, Canada
12:45 p.m.
Franklin Hall B
WHAT CONSTITUTES A WELL VERSUS POORLY-WRITTEN
MANUSCRIPT: RESPONDING TO REVIEWERS’ COMMENTS
Monday, November 5, 2007 1:30 p.m. - 7 p.m.
James Kazura
Symposium 33
12:50 p.m.
Diagnostics in the Tropics – Time to Take the
Guesswork Out of Clinical Practice
WHAT CONSTITUTES A WELL VERSUS POORLY-WRITTEN
MANUSCRIPT: RESPONDING TO REVIEWERS’ COMMENTS
Salon AB
Joseph M. Vinetz
In many parts of the tropics, there is no adequate laboratory service. Whilst
syndromic treatment algorithms have proven successful in some contexts,
lack of a confirmed diagnosis can result in unnecessary treatment, resulting
in drug wastage and the encouragement of resistance on the one hand and
delayed discovery of the correct diagnosis on the other. Technological
advances now give the opportunity to achieve a precise diagnosis of a variety of conditions in the field. This symposium will highlight these advances
and their potential impact in the tropics.
12:55 p.m.
THE REVIEW: EDITORIAL, CORRESPONDING AUTHOR AND
REVIEWER PERSPECTIVES
James Kazura
1 p.m.
CHAIR
THE REVIEW: EDITORIAL, CORRESPONDING AUTHOR AND
REVIEWER PERSPECTIVES
Peter L. Chiodini
Hospital for Tropical Diseases, London, United Kingdom
Joseph M. Vinetz
Mark Perkins
Foundation for Innovative New Diagnostics, Geneva, Switzerland
1:05 p.m.
1:30 p.m.
OPEN FORUM
DIAGNOSTICS FOR SEXUALLY TRANSMITTED INFECTIONS
Rosanna Peeling
World Health Organization, Geneva, Switzerland
85
Monday, November 5
www.astmh.org
Detailed Program
2 p.m.
2:30 p.m.
QUALITY ASSESSMENT IN PARASITOLOGY: THE TEMPERATE
AND THE TROPICAL
RNAI IS ALIVE AND WELL IN LEISHMANIA BRAZILIENSIS
Peter L. Chiodini
Washington University in St. Louis, St. Louis, MO, United States
Steve M. Beverley
2:25 p.m.
DEVELOPMENTS IN TB DIAGNOSTICS
Malaria - Immunology I
Mark Perkins
Salon E
Foundation for Innovative New Diagnostics, Geneva, Switzerland
2:50 p.m.
CHAIR
MALARIA DIAGNOSTICS: OBTAINING RESULTS THAT CAN
INFLUENCE MANAGEMENT
Clara Menendez
University of Barcelona, Barcelona, Spain
David Bell
Martha Sedegah
World Health Organization, Manila, Philippines
Naval Medical Research Center, Silver Spring, MD, United States
1:30 p.m.
Symposium 34
300
Cell and Molecular Biology of Trypanosomatid
Infections: Parasite Biology
THE ACQUISITION OF INVASION INHIBITORY ANTIBODIES
AND ANTIBODIES TO ERYTHROCYTE INVASION LIGANDS
OF P. FALCIPARUM
Salon CD
Fiona McCallum1, Kristina Persson1, Cleopatra Mugyenyi2, Linda
Reiling1, Jack Richards1, Tom Williams2, Robin Anders3, Alan
Cowman1, Kevin Marsh2, James Beeson1
The symposium will focus on recent advances in understanding the cell and
molecular biology associated with survival of African trypanosomes and
Leishmania in their mammalian hosts and insect vectors. Talks will be on
chromatin modifications at chromosomal telomeres associated with antigenic variation in African trypanosomes, mechanisms of RNAi and gene
expression in leishmania and the significance of cell motility in African trypanosomes.
1
The Walter and Eliza Hall Institute of Medical Research, Parkville, Australia,
Centre for Geographic Medicine Research, Kenya Medical Research
Institute, Kilifi, Kenya, 3Latrobe University, Melbourne, Australia
2
1:45 p.m.
301
CHAIR
TWO LONGITUDINAL COHORT STUDIES INVESTIGATING
MECHANISMS OF INNATE AND ACQUIRED IMMUNITY TO
MALARIA IN CHILDREN FROM HIGHLY ENDEMIC REGIONS OF
PAPUA NEW GUINEA
John E. Donelson
Mary E. Wilson
Leanne J. Robinson1, Marthe C. D’Ombrain1, Enmoore Lin2, Jack
Taraika2, Nicholas Bernard1, Pascal Michon2, Chris L. King3, James
G. Beeson1, Danielle I. Stanisic2, Ivo Mueller2, Louis Schofield1
1:30 p.m.
PARSING CHROMATIN MODIFICATIONS FOR RELEVANCE TO
ANTIGENIC VARIATION IN TRYPANOSOMA BRUCEI
1
The Walter & Eliza Hall Institute of Medical Research, Parkville, Australia,
Papua New Guinea Institute of Medical Research, Madang, Papua New
Guinea, 3Center for Global Health and Diseases, Case Western Reserve
University, Cleveland, OH, United States
2
George A. Cross
Rockefeller University, New York, NY, United States
(ACMCIP Abstract)
1:50 p.m.
2 p.m.
DEVELOPMENTAL GENE REGULATION IN LEISHMANIA
302
Barbara Papadopoulou
2:10 p.m.
THE RATE OF ACQUISITION OF HUMAN ANTIBODY ISOTYPE
PROFILES TO PLASMODIUM FALCIPARUM BLOOD STAGE
ANTIGENS IN GAMBIAN INFANTS
PARASITES IN MOTION: MECHANISM AND BIOLOGY OF
FLAGELLAR MOTILITY IN AFRICAN TRYPANOSOMES
Nancy O. Duah1, Kevin Tetteh1, Onome Akpogheneta1, Spencer
Polley1, Patrick Corran1, Hilton Whittle2, David J. Conway2
Laval University, Quebec, QC, Canada
1
London School of Hygiene and Tropical Medicine, London, United
Kingdom, 2Medical Research Council-The Gambia, Banjul, Gambia
Kent Hill
University of California at Los Angeles, Los Angeles, CA, United States
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Symposium 36
303
American Committee of Medical Entomology (ACME) I:
Andrew Spielman’s Contributions to Medical
Entomology
MULTIPLEXED MEASUREMENT OF EPSTEIN BARR VIRUS,
CYTOMEGALOVIRUS AND P. FALCIPARUM-SPECIFIC ANTIBODIES USING THE LUMINEX SYSTEM
Salon F
Erwan Piriou1, Kiprotich Chelimo1, Rhonda Kimmel2, Sheetij
Dutta3, Carole Long4, David E. Lanar3, Jaap M. Middeldorp5, Ann
M. Moormann2, Rosemary Rochford6
The late Andy Spielman, an ASTMH member since the mid 1950s, is
remembered for his contributions to tropical medicine and to medical entomology in general. This ACME symposium will attempt to summarize Andy’s
perspective and influence on medical entomology.
Center for Vector Biology and Control Research, Kenyan Medical Research
Institute, Kisumu, Kenya, 2Case Western Reserve University, Cleveland, OH,
United States, 3Walter Reed Army Institute of Research, Silver Spring, MD,
United States, 4National Institute of Allergy and Infectious Diseases, National
Institutes of Health, Rockville, MD, United States, 5Vrije Universiteit Medical
Center, Amsterdam, The Netherlands, 6SUNY Upstate Medical University,
Syracuse, NY, United States
CHAIR
Sam R. Telford
Tufts University, North Grafton, MA, United States
2:30 p.m.
Kenneth Linthicum
304
United States Department of Agriculture, Gainesville, FL, United States
IMMUNOGENICITY OF A MULTI-STAGE, MULTI-ANTIGEN
ADENOVIRUS-VECTORED P. FALCIPARUM MALARIA VACCINE
1:30 p.m.
HISTORY OF MEDICAL ENTOMOLOGY AT HARVARD
Martha Sedegah1, David Regis1, Harini Ganeshan1, Stephen Abot1,
Glenna Banania1, Denise L. Doolan1, Keith Limbach1, Joseph
Bruder2, Christopher King2, Noelle Patterson1, Jose MendozaSilveiras1, Sharina Reyes1, Frank Williams3, Ilin Chuang1, Lorraine
Soisson4, Carter Diggs4, Thomas Richie1
Sam R. Telford
1:55 p.m.
1
Naval Medical Research Center, Silver Spring, MD, United States, 2GenVec
Inc., Gaithersburg, MD, United States, 3National Medical Research Center,
Bethesda, MD, United States, 4United States Agency for International
Development, Washington, DC, United States
TEACHING PUBLIC HEALTH ENTOMOLOGY
Richard J. Pollack
2:45 p.m.
2:20 p.m.
305
TRENDS IN MEDICAL ENTOMOLOGY
IMMUNOLOGICAL STUDIES OF P. FALCIPARUM MEROZOITE
SURFACE PROTEIN 1, MSP1-33 AND ITS POTENTIAL
INFLUENCE TOWARD MSP1 VACCINE DESIGN
Duane Gubler
Kae Pusic1, Caryn Hashimoto1, Walter Ho2, David Clements3,
George Hui1
2:50 p.m.
1
Asia-Pacific Institute of Tropical Medicine and Infectious Disease, Honolulu,
HI, United States
THE VECTOR BIOLOGY PROGRAM AT NATIONAL INSTITUTE
OF ALLERGY AND INFECTIOUS DISEASES: PAST, PRESENT
AND FUTURE
2
University of Hawaii, Honolulu, HI, United States, Chinese University of
Hong Kong, Shatin, Hong Kong, 3Hawaii Biotech Inc., Aiea, HI, United
States
Adriana Costero
3 p.m.
National Institute of Allergy and Infectious Diseases, Bethesda, MD,
United States
306
IMPACT OF INTERMITTENT PREVENTIVE TREATMENT WITH
SULFADOXINE-PYRIMETHAMINE ON THE DEVELOPMENT OF
IMMUNE RESPONSES TO PLASMODIUM FALCIPARUM IN
MOZAMBICAN CHILDREN
Carlota Dobaño1, Diana Quelhas2, Laura Puyol1, Llorenç Quintó1,
Elisa Serra-Casas1, Tacilta Nhampossa2, Eusebio Macete2, Pedro
Aide2, Alfredo Mayor1, Inacio Mandomando2, Sergi Sanz1, John J.
Aponte1, Chetan Chitnis3, Pedro L. Alonso1, Clara Menéndez1
1
Centre de Salut Internacional, Hospital Clínic, Institut d’Investigacions
Biomèdicas August Pi i Sunyer, Universitat de Barcelona, Barcelona, Spain,
2
Centro de Investigaçao em Saude da Manhiça, Manhiça, Mozambique,
3
International Centre for Genetic Engineering and Biotechnology,
New Delhi, India
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Detailed Program
Symposium 37
of late trachoma, on the use of antibiotics to eliminate the ocular reservoir
of Chlamydia trachomatis infection and on the pathogenesis of scarring trachoma and its relationship to ocular infection will be reviewed, leading to
recommendations on the optimal strategies for trachoma control and for
the certification of its elimination.
Chagas’ Disease
Salon G
CHAIR
This symposium will focus on Chagas’ disease with special emphasis on
development of novel chemotherapy, diagnosis and treatment of human
and murine Chagas’ disease, experimental evidence on the biological role of
the T. cruzi protease cruzain in immune evasion and the mechanism of
action of cysteine protease inhibitors.
David C. Mabey
1:30 p.m.
CHAIR
PREVENTION OF BLINDNESS FROM TRACHOMA: IMPROVING
SURGERY FOR TRICHIASIS
Patricia S. Doyle
Sheila West
University of California, San Francisco, San Francisco, CA, United States
Johns Hopkins University, Baltimore, MD, United States
James H. McKerrow
1:55 p.m.
ELIMINATION OF INFECTIOUS TRACHOMA FROM THE
MOST SEVERELY AFFECTED AREAS WITH MASS
AZITHROMYCIN DISTRIBUTIONS
1:30 p.m.
NOVEL ERGOSTEROL BIOSYNTHESIS INHIBITORS AS SPECIFIC
CHEMOTHERAPEUTIC AGENTS FOR CHAGAS’ DISEASE
Thomas Lietman
University of California at San Francisco, San Francisco, CA, United States
Julio Urbina
Instituto Venezolano de Investigaciones Científicas, Caracas, Venezuela
2:20 p.m.
1:50 p.m.
TARGETING AZITHROMYCIN TREATMENT FOR
TRACHOMA ELIMINATION: LESSONS FROM THE
ENDGAME IN THE GAMBIA
PROGRESS IN DEVELOPING STEROL C14-DEMETHYLASE
INHIBITORS FOR CHAGAS’ DISEASE
Robin Bailey
Frederick S. Buckner
2:45 p.m.
2:10 p.m.
STUDIES ON THE PATHOGENESIS OF SCARRING TRACHOMA
AND TRICHIASIS
DEVELOPING NEW DRUGS FOR CHAGAS’ DISEASE IN AN ACADEMIC INCUBATOR
Matthew Burton
James H. McKerrow
2:30 p.m.
Symposium 39
DIAGNOSIS AND TREATMENT OF HUMAN (AND MURINE)
CHAGAS’ DISEASE
Parasitic and Vector-Borne Zoonoses
Rick L. Tarleton
Supported with funding from The Companion Animal
Parasite Council
2:50 p.m.
Salon IJ
THE TRYPANOSOMA CRUZI PROTEASE CRUZAIN MEDIATES
IMMUNE EVASION
Interesting human cases of zoonotic parasitism and vector-borne zoonoses
will be presented, with opportunity for audience participation in diagnosis
and management. Cases will illustrate new scientific or public health developments relevant to clinical practice.
Patricia S. Doyle
CHAIR
Symposium 38
Leonard C. Marcus
Travelers’ Health and Immunization Services, Newton, MA, United States
The Elimination of Blinding Trachoma
Salon H
This symposium will review progress towards the goal of eliminating blinding trachoma by the year 2020. Recent research on the surgical treatment
88
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1:30 p.m.
2:25 p.m.
THE COMPANION ANIMAL PARASITE COUNCIL: A USEFUL
RESOURCE
MECHANISMS SUPPORTING ODOR AND CARBON DIOXIDE
DETECTION IN MOSQUITOES
Michael Paul
Leslie Vosshall
Companion Animal Parasite Council, Anguilla, Anguilla
The Rockefeller University, New York, NY, United States
1:55 p.m.
2:50 p.m.
UNUSUAL CASES OF HELMINTHIC ZOONOSES
PROSPECTS FOR THE FUTURE
Peter Schantz
Daniel Strickman
U.S. Department of Agriculture, Beltsville, MD, United States
2:20 p.m.
Symposium 41
A CAT CAUSES A PUBLIC HEALTH PROBLEM
Leonard C. Marcus
Travelers’ Health and Immunization Services, Newton, MA, United States
Programming National Malaria Control for
Impact in Africa
2:45 p.m.
Liberty AB
THIS MITE BE A PROBLEM
Richard Pollack
Malaria control scale-up for impact is a programming approach to rapidly
implementing high coverage of an epidemiologically tailored package of
proven malaria interventions to achieve, sustain and document health and
economic impact. Several African countries are partnering with global
organizations (notably the World Bank Global Strategy and Booster
Program; the Global Fund for AIDS, Tuberculosis and Malaria; the U.S.
President’s Malaria Initiative; and the MACEPA program at PATH) to develop
the methods and document the results of national scale-up for impact
efforts. This intensified commitment to national-scale malaria control constitutes a multi-country, evidence-based demonstration of the feasibility and
benefits of comprehensive malaria control programming. This symposium
will examine African countries’ preparedness for scale-up, the approaches
being deployed, the results from two representative countries and the key
challenges to sustaining and expanding global support of malaria control
scale-up in Africa.
Symposium 40
Novel Approaches to Designing Mosquito Repellents
Salon KL
Humans and many other organisms have long sought products to keep
arthropods, including mosquitoes, from biting. Although incompletely effective, significant resources are spent on mosquito repellents even in developing countries where income is limited. Efforts to identify the odorant genes
and receptors that enable mosquitoes to seek out their preferred hosts have
been accelerated by the availability of complete genomic sequence data for
the mosquito vectors of malaria and dengue. Speakers will consider rational
approaches for designing new repellents and assessing their effectiveness
based on the recent advances.
CHAIR
Carlos (Kent) C. Campbell
CHAIR
David Brandling-Bennett
Michael Gottlieb
Foundation for the National Institutes of Health, Bethesda, MD,
United States
Simon K. Miti
Ministry of Health, Zambia, Lusaka, Zambia
1:30 p.m.
1:30 p.m.
INTERFERING WITH MOSQUITO’S ATTRACTION TO HUMANS
INTRODUCTION
Mustapha Debboun
David Brandling-Bennett
U.S. Army Medical Department Center and School, Fort Sam Houston, TX,
United States
2 p.m.
1:40 p.m.
MOSQUITO GENOME PROJECTS: ODORANT GENES AND
RECEPTORS FUEL DISCOVERY OF NEW APPROACHES TO AN
OLD PROBLEM
INTRODUCTION
Simon K. Miti
Ministry of Health, Zambia, Lusaka, Zambia
Laurence J. Zwiebel
Vanderbilt University, Nashville, TN, United States
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Detailed Program
1:50 p.m.
2 p.m.
307
STATUS OF MALARIA PROGRAM COVERAGE IN THE AFRICA
REGION: ANALYISIS OF SURVEY DATA, 2005 - 2007
CYTOKINE GENE AND PROMOTER POLYMORPHISMS IN
HUMAN SCHISTOSOMIASIS MANSONI
Bernard Nahlen
President’s Malaria Initiative, Washington, DC, United States
Michael R. Gatlin1, Carla L. Black1, Pauline N. Mwinzi2, W. Evan
Secor3, Diana M. Karanja2, Daniel G. Colley1
2 p.m.
1
University of Georgia, Athens, GA, United States, 2Kenya Medical Research
Institute, Kisumu, Kenya, 3Centers for Disease Control and Prevention,
Atlanta, GA, United States
ZAMBIA’S MALARIA CONTROL PLANNING SYSTEM AND
RESULTS OF PROGRAM SCALE-UP, 2005 - 2007
Elizabeth Chizema
(ACMCIP Abstract)
Ministry of Health, Lusaka, Zambia
2:15 p.m.
2:20 p.m.
308
ETHIOPIA’S PROGRESS IN ACCELERATING NATIONAL MALARIA
CONTROL
INVESTIGATIONS INTO THE UPTAKE AND ROLE OF IRON IN
SCHISTOSOMES
Afework Hailemariam
Malcolm Jones, Amber Glanfield
Federal Ministry of Health, Addis Ababa, Ethiopia
Queensland Institute of Medical Research, Herston, Queensland, Australia
2:40 p.m.
(ACMCIP Abstract)
IT TAKES MORE THAN FUNDING: THE CRITICAL ROLE OF
PARTNERS IN SUPPORTING SCALE-UP
2:30 p.m.
309
Awa Marie Coll-Seck
Roll Back Malaria Partnership, Geneva, Switzerland
BLOOD FLUKE EXPLOITATION OF INNATE-ADAPTIVE IMMUNE
INTERACTIONS TO FACILITATE PARASITE DEVELOPMENT
3 p.m.
Erika W. Lamb1, Emily T. Crow1, John T. Pesce2, Thomas A. Wynn2,
Brian C. Schaefer1, Stephen J. Davies1
HOW READY ARE AFRICAN COUNTRIES TO SCALE UP FOR
IMPACT? RESULTS OF GAP ANALYSIS
1
States, 2National Institutes of Health, Bethesda, MD, United States
Melanie Renshaw
(ACMCIP Abstract)
2:45 p.m.
310
Franklin 3/4
ASSOCIATION BETWEEN PRETREATMENT CYTOKINE PRODUCTION AND INTENSITY OF INFECTION AND RESISTANCE TO
REINFECTION IN HUMAN SCHISTOSOMIASIS MANSONI
1:30 p.m. - 3:15 PM
Carla L. Black1, Pauline N. Mwinzi2, Erick M. Muok2, Bernard
Abudho2, W. Evan Secor3, Diana M. Karanja2, Daniel G. Colley1
CHAIR
1
University of Georgia, Athens, GA, United States, 2Kenya Medical Research
Institute, Kisumu, Kenya, 3Centers for Disease Control and Prevention,
Schistosomiasis I - Immunology/Parasite Development
Daniel G. Colley
(ACMCIP Abstract)
Stephen Davies
3 p.m.
States
311
+
1:30 p.m.
ROLE OF CD4 T CELL RESPONSES DURING EARLY
SCHISTOSOME INFECTION
MULTI-CYTOKINE KNOCKOUT MICE AS TOOLS TO STUDY THE
PATHOGENESIS OF FIBROSIS
Mazen Makarem1, Tuere Wilder2, Anna Tocheva1, Lucia A. Fraga1,
Bruce N. Cronstein2, Stephen J. Davies1
Thomas A. Wynn
1
States, 2Department of Medicine, Division of Clinical Pharmacology, New
York, NY, United States
Diseases, Bethesda, MD, United States
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Exhibit Hall Open
Franklin Hall B
Kinetoplastida I: Molecular Biology and Immunology
Monday, November 5, 2007 3 p.m. - 4 p.m.
Salon CD
Coffee Break
3:45 p.m. - 5:30 PM
Franklin Hall B
CHAIR
Symposium 43
Walderez O. Dutra
M(X)DR-Tuberculosis: A Global Threat
Federal University of Minas Gerais, Belo Horizonte, Brazil
Salon AB
3:45 p.m.
312
On September 1, 2006, the World Health Organization (WHO) announced
that a deadly new strain of extensively drug-resistant tuberculosis (XDR-TB)
had been detected in Tugela Ferry, a rural town in the South African
Province of KwaZulu Natal, the epicenter of South Africa’s HIV epidemic.
Tuberculosis, already the world’s fourth most fatal infectious disease, could
wreak havoc with AIDS treatment program. The speakers will update on the
current epidemiology, clinical and public health strategies to efficiently
address the global challenge of this emerging threat.
DISPARATE IMMUNOREGULATORY POTENTIALS FOR CD4-CD8ALPHA/BETA AND GAMMA/DELTA T CELLS FROM
CUTANEOUS LEISHMANIASIS PATIENTS
Lis R. Antonelli1, Olivia Bacellar2, Luis Guimaraes2, Edgar Carvalho2,
Walderez O. Dutra1, Kenneth J. Gollob3
1
CHAIR
UFMG, Belo Horizonte, MG, Brazil, 2UFBA-Immunology Service, Hospital
Edgard Santos, Salvador, BA, Brazil, 3UFMG-Department of BiochemistryImmunology, Belo Horizonte, MG, Brazil
Jean B. Nachega
(ACMCIP Abstract)
4 p.m.
Rocio Hurtado
313
Harvard Medical School-MGH, Boston, MA, United States
GBV-C VIREMIA INFLUENCE DTH RESPONSE TO LEISHMANIA
3:45 p.m.
Josane R. Lima1, Jose Wilton Queiroz1, Daniel Leung2, Henio G.
Lacerda1, Eliana L. Nascimento1, Daniella R. Martins1, Richard D.
Pearson3, Mary E. Wilson2, Jack T. Stapleton2, Selma M. Jeronimo1
XDR-TB OUTBREAK IN TUGELA FERRY, KWA-ZULU NATAL,
SOUTH AFRICA
1
Universidade Federal do Rio Grande do Norte, Natal, Brazil, 2University of
Iowa, Iowa City, IA, United States, 3University of Virginia, Charlottesville, VA,
United States
4:10 p.m.
4:15 p.m.
Jean Nachega
314
PROGRAMMATIC MODEL OF MDR-TB TREATMENT IN PERU
Rocio Hurtado
NEUTROPHILS DOMINATE THE EARLY INFLAMMATORY
RESPONSE DURING ACUTE INTRADERMAL INFECTION WITH
LEISHMANIA CHAGASI
Harvard Medical School-MGH, Boston, MA, United States
4:35 p.m.
Colin J. Thalhofer1, A. Paige Davis1, Mary E. Wilson2
NOVEL LABORATORY DIAGNOSTIC APPROACHES OF M(X) DRTB IN RESOURCE-LIMITED SETTINGS
1
University of Iowa, Iowa City, IA, United States, 2University of Iowa, VA
Medical Center, Iowa City, IA, United States
Robert Gilman
(ACMCIP Abstract)
4:30 p.m.
5 p.m.
315
MODELING ASPECTS OF XDR-TUBERCULOSIS IN SETTING
WITH HIGH HIV PREVALENCE
DETERMINATION OF CANINE IMMUNE DEFICITS WHICH PREDISPOSE TO INFECTION WITH LEISHMANIA INFANTUM
Amanda Ramer-Tait, Jack Gallup, Erin Kramer, Doug Jones,
Christy Petersen
David Dowdy
(ACMCIP Abstract)
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Monday, November 5
Christine Petersen
Detailed Program
www.astmh.org
4:45 p.m.
4 p.m.
316
320
OLIGOCLONAL EXPANSIONS AMONG SPECIFIC Vβ
EXPRESSING T CELLS IN HUMAN CHAGAS DISEASE
INFECTION-INDUCED CYTOKINE PRODUCTION INFLUENCES
THE SUPPRESSION OF PLASMODIUM YOELII PARASITEMIA
FOLLOWING PROTECTIVE IMMUNIZATION
Cristiane A. Menezes1, Andrew K. Sullivan2, Michael T. Falta2,
Douglas G. Mack2, Brian Freed2, Manoel O. Rocha1, Kenneth J.
Gollob1, Andrew P. Fontenot2, Walderez O. Dutra1
Patricia M. Petritus, James M. Burns
1
Federal University of Minas Gerais, Belo Horizonte, Brazil, 2University of
Colorado Health Sciences Center, Denver, CO, United States
(ACMCIP Abstract)
(ACMCIP Abstract)
4:15 p.m.
321
5 p.m.
317
FUNCTIONAL ASSOCIATIONS BETWEEN HAPLOTYPES OF
NITRIC OXIDE SYNTHASE TYPE 2 (NOS2) PROMOTER VARIANTS (-954G/C AND -1173C/T), PEDIATRIC SEVERE MALARIAL
ANEMIA, AND HIGH-DENSITY PARASITEMIA
Collins Ouma1, Gordon Awandare2, Gregory Davenport2,
Christopher Keller3, Dorothy Opondo1, Tom Were1, Richard Otieno1,
Michael Otieno4, Alloys Orago4, John Vulule5, John Michael
Ong’echa1, Jeremy Martinson2, Robert Ferrell2, Douglas Perkins2
COMPARISON OF IMMUNE RESPONSES DURING LEISHMANIASIS THERAPY
Mary Marovich
Walter Reed Army Institute of Research, Rockville, MD, United States
(ACMCIP Abstract)
1
Pittsburgh, PA, United States, 3University of Pittsburgh/Lake Erie College of
Ostepathic Medicine, Pittsburgh, PA, United States, 4Kenyatta University,
Nairobi, Kenya, 5KEMRI, Kisumu, Kenya
5:15 p.m.
318
MOLECULAR IDENTIFICATION OF THE GREGARINES OF PHLEBOTOMINE SAND FLIES
1
2
1
(ACMCIP Abstract)
1
Kashinath Ghosh , Henk R. Braig , Phil Lawyer , Peter Weina ,
Edgar Rowton1
4:30 p.m.
322
1
University of Wales, Bangor, United Kingdom
2
PLACENTAL INTERFERON-γ AND CORD BLOOD FERRITIN ARE
RELATED TO BIRTH WEIGHT IN AN AREA OF INTENSE MALARIA TRANSMISSION
Malaria - Immunology II
Edward R. Kabyemela1, Michal Fried2, Jonathan Kurtis3, Theonest
Mutabingwa1, Patrick Duffy2
1
MOMS Project Muheza Tanzania, Tanga, United Republic of Tanzania,
MOMS Project Seattle Biomedical Research Institute, Seattle, WA, United
States, 3Brown University, Providence, RI, United States
Salon E
2
3:45 p.m. - 5:30 PM
(ACMCIP Abstract)
CHAIR
4:45 p.m.
Joanne Lumsden
323
COMPLEMENT UTILIZATION IN CHILDREN WITH SEVERE
MALARIA ANEMIA
John Waitumbi
Nancy K. Nyakoe1, John N. Waitumbi1, Ron P. Taylor2
3:45 p.m.
1
Walter Reed Project/Kenya Medical Research Institute, Kisumu, Kenya,
Department of Biochemistry and Molecular Genetics, University of Virginia
School of Medicine, Charlottesville, VA, United States
2
319
GENETICALLY-ATTENUATED PLASMODIUM BERGHEI LIVERSTAGES INDUCE STERILE PROTRACTED PROTECTION THAT IS
MEDIATED BY MHC CLASS I-DEPENDENT IFN-γ PRODUCING
CD8+ T CELLS
(ACMCIP Abstract)
Ousman Jobe1, Joanne Lumsden1, Robert J. Schwenk1, Jackie
Williams1, Stefan Kappe2, Kai Matuschewski3, Urszula Krzych1
1
SBRI, Seattle, WA, United States, 3Univeristy of Heidelberg, Heidelberg,
Germany
2
(ACMCIP Abstract)
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4:35 p.m.
5 p.m.
324
EPIDEMIOLOGY OF BABESIOSIS
Peter J. Krause
EFFECTS OF CONCOMITANT SCHISTOSOMA HAEMATOBIUM
INFECTION ON THE INTRACELLULAR CYTOKINE LEVELS AND T
CELL MEMORY POPULATIONS ELICITED BY ACUTE
PLASMODIUM FALCIPARUM MALARIA INFECTION IN MALIAN
CHILDREN
2
5:05 p.m.
PERPETUATION OF ARBOVIRUSES
Michael J. Turell
2
Kirsten E. Lyke , Abdoulaye Dabo , Charles Arama , Modibo
Daou2, Issa Diarra2, Christopher V. Plowe1, Ogobara K. Doumbo2,
Marcelo B. Sztein1
United States Army Medical Research Institute for Infectious Diseases,
1
2
Symposium 47
(ACMCIP Abstract)
Johns Hopkins Malaria Research Institute Symposium
on Determinants of Malaria Transmission
5:15 p.m.
325
Salon IJ
MALARIA AND HELMINTHES CO-INFECTIONS IN CHILDREN
AGED 6-17 YEARS IN THE BURMA VALLEY AREA OF
ZIMBABWE
Factors that influence transmission of the malaria parasite are complex.
Transmission depends on the successful development of the parasite in the
human host and in the obligate mosquito vector. Speakers will be asked to
provide an overview of the different factors affecting malaria transmission
and to relate recent discoveries to potential new strategies for disease control.
Davison T. Sangweme1, Nicholas Midzi2, Sekesai Zinyowera3,
Takafira Mduluza4, Nirbhay Kumar1
1
Johns Hopkins University, Baltimore, MD, United States, 2National Institute
of Health Research, Harare, Zimbabwe, 3University of Zimbabwe,
Department of Medical Microbiology, Harare, Zimbabwe, 4University of
Zimbabwe, Department of Biochemistry, Harare, Zimbabwe
CHAIR
Marcelo Jacobs-Lorena
(ACMCIP Abstract)
Symposium 46
3:45 p.m.
American Committee of Medical Entomology (ACME) II:
Andrew Spielman’s Contributions to Medical
Entomology
AN EVOLUTIONARY PERSPECTIVE TO UNDERSTANDING
MALARIA-TRANSMITTING ANOPHOLINES
Jeffrey R. Powell
Salon F
4:15 p.m.
The late Andy Spielman, an ASTMH member since the mid-1950s, is
remembered for his contributions to tropical medicine and to medical entomology in general. This ACME symposium will attempt to summarize Andy’s
perspective and influence on medical entomology.
MALARIA IN THE MOSQUITO BLOOD MEAL: FROM PROTEOMES AND MOLECULES, TO BIOLOGY
Robert E. Sinden
CHAIR
Sam R. Telford
4:40 p.m.
PLASMODIUM DEVELOPMENT IN THE MOSQUITO
Kenneth Linthicum
Marcelo Jacobs-Lorena
3:45 p.m.
5:05 p.m.
ANTIMALARIA INTERVENTION
IMMUNITY TARGETING MALARIA TRANSMISSION
Uriel Kitron
Nirbhay Kumar
University of Illinois, Urbana, IL, United States
4:10 p.m.
Symposium 48
THE ECOLOGICAL PERSPECTIVE IN MEDICAL ENTOMOLOGY
Mark L. Wilson
Fascioliasis – New Developments in Epidemiology,
Immunology and Molecular Approaches of
Snail/Human Relationships
University of Michigan School of Public Health, Ann Arbor, MI, United States
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University of Connecticut School of Medicine, hartford, CT, United States
www.astmh.org
Detailed Program
Salon KL
CHAIR
Ian Bathurst
Fascioliasis is an emerging disease of humans, increasingly found worldwide
both in the tropical as well as temperate climates. Recent studies have
focused on epidemiologic patterns of disease transmission in hyperendemic
areas of Latin America. Studies on differences in immune responses to juvenile stages have shown species differences between F. hepatica and F. gigantica, suggesting differential approaches to vaccines. Vaccine approaches
with new vaccine formulations show promise to both decrease disease and
transmission in experimental models. Finally, a molecular approach to study
the relationships between lymnaeid vectors and human fascioliasis focusing
on the Americas will be presented.
Winston Gutteridge
Medicines for Malaria Venture, Sevenoaks, United Kingdom
3:45 p.m.
PSAC ANTAGONISTS AS LEAD COUMPOUNDS FOR ANTIMALARIAL DEVELOPMENT
Sanjai Desai
National Institute of Allergy and Infectious Diseases/National Institutes of
CHAIR
George V. Hillyer
4:15 p.m.
University of Puerto Rico School of Medicine, San Juan, PR, United States
NOVEL INHIBITORS OF MALARIAL DHFR
3:45 p.m.
Yongyuth Yuthavong
HUMAN FASCIOLIASIS DISEASE TRANSMISSION
AND EPIDEMIOLOGIC PATTERNS IN ENDEMIC AREAS
OF LATIN AMERICA
Biotec Thailand, Bangkok, Thailand
Santiago Mas Coma
SECOND GENERATION SYNTHETIC PEROXIDE ANTIMALARIALS
University of Valencia, Valencia, Spain
Susan Charman
4:10 p.m.
Monash University, Victoria, Australia
NEWLY EXCYSTED JUVENILES OF F. HEPATICA AND
F. GIGANTICA DIFFER IN SUSCEPTIBILITY TO IMMUNE
EFFECTOR MECHANISMS IN VITRO: IMPLICATIONS
FOR CONTROL OF FASCIOLOSIS
5 p.m.
Terry W. Spithill
GlaxoSmithKline, Madrid, Spain
4:40 p.m.
4-PYRIDONES AS PUTATIVE ANTIMALARIALS
Domingo Gargallo
McGill University, St. Anne de Bellevue, QC, Canada
Symposium 50
4:35 p.m.
ADAD AS A SYSTEM OF VACCINATION AGAINST F. HEPATICA
Outbreak Reporting Mechanisms
Antonio Muro
Franklin 1
University of Salamanca, Salamanca, Spain
5 p.m.
Information about the occurrence of epidemic outbreaks is fragmented
among multiple sources, but many of them suffer from considerable delays.
Additionally, their representativeness remains fairly unknown and it is
unclear how much overlap exists between these disparate sources. This symposium presents some of the main sources identified, describing their
strengths, limitations, possible overlap and potential for integration.
RELATIONSHIPS BETWEEN LYMNAEID VECTORS AND HUMAN
FASCIOLIASIS IN THE AMERICAS – A MOLECULAR APPROACH
M. D. Bargues
University of Valencia, Valencia, Spain
CHAIR
Symposium 49
Andres G. Lescano
U.S. Naval Medical Research Center Detachment, Lima, Peru
Medicines for Malaria Venture’s (MMV’s) Drug
Discovery Portfolio
David L. Blazes
Liberty AB
3:45 p.m.
CENTERS FOR DISEASE CONTROL AND PREVENTION‘S
OUTBREAK REPORTS
Medicines for Malaria Venture is funding a number of discovery research
projects aimed at designing new drugs for the treatment of malaria. The
aim of the symposium is to demonstrate how molecular biologists, parasitologists, biophysicists, medicinal chemists and pharmacists work together to
seek to accomplish such goals. It will indicate that modern genomics, combinatorial chemistry and high throughput screening have revolutionized the
process. At the same time, it will show how, despite such advances, projects
are time-consuming, costly and highly speculative.
Ray R. Arthur
94
4:15 p.m.
www.astmh.org
4 p.m.
327
PROMED: MONITORING EMERGING DISEASE OUTBREAKS
THROUGH UNOFFICIAL SOURCES
Harvard Medical School, Boston, MA, United States
4:40 p.m.
Leonard Peruski1, Wanna Wongjindanon1, Boonchuay
Eampokalap2, Leelaowadee Sangsuk2, Possawat Jorakate1, Anek
Kaewpan1, Prasert Salika1, Prabda Prapasiri1, Sathapana Naorat1,
Somsak Rienthong2, Henry Baggett1, Susan Maloney1
GLOBAL OUTBREAK ALERT AND RESPONSE NETWORK
Marlo Libel
Pan-American Health Organization, Washington, DC, United States
1
International Emerging Infections Program, Bangkok, Thailand, 2Ministry of
Public Health, Bangkok, Thailand
5:05 p.m.
OUTBREAK REPORTS IN (AND OUT OF) THE SCIENTIFIC
LITERATURE
4:15 p.m.
328
Gabriela Salmón-Mulanovich
Naval Medical Research Center Detachment, Lima, Peru
TRANSMISSION OF BACTERIA RATHER THAN ANTIBIOTIC USE
DETERMINES RESISTANCE LEVELS: DATA AND MODELS FROM
NORTHERN ECUADOR
Joseph N. Eisenberg1, William Cevallos2, Gabriel Trueba2, Rosana
Segovia2, Karen Levy3, James Scott4, Alan Hubbard3, Betsy Foxman1,
Carl Marrs1, Lixin Zhang1, James Trostle5
Bacteriology III
1
University of Michigan, Ann Arbor, MI, United States, 2Universidad San
Francisco de Quito, Quito, Ecuador, 3University of California, Berkeley,
Berkeley, CA, United States, 4University of California, Berkeley, Ann Arbor,
CA, United States, 5Trinity College, Hartford, CT, United States
Franklin 2
CHAIR
Samba O. Sow
4:30 p.m.
Center for Vaccine Development - Mali, Bamako, Mali
329
Michael Y. Kosoy
ANTIBIOTIC USE BEFORE CULTURE REDUCES BACTERIAL YIELD
AMONG PATIENTS EVALUATED FOR COMMUNITY-ACQUIRED
BACTEREMIA IN THAILAND
3:45 p.m.
326
Cynthia Fisher1, Henry Baggett2, Possawat Jorakate3, Wanna
Wongjindanon2, Boonchuay Eampokalap4, Somsak Thamthitiwat2,
Sonja Olsen5, Julia Rhodes2, Leelaowadee Sangsuk6, Susan
Maloney2, Leonard Peruski2
EARLY IMPACT OF HAEMOPHILUS INFLUENZAE TYPE B VACCINE INTRODUCTION INTO THE ROUTINE EXPANDED
IMMUNIZATION PROGRAMME IN BAMAKO, MALI
1
Johns Hopkins School of Medicine, Baltimore, MD, United States,
International Emerging Infections Program, Thailand Ministry of Public
Health-U.S. Centers for Disease Control and Prevention Collaboration,
Nonthaburi, Thailand, 3International Emerging Infections Program, Thailand
Ministry of Public Health-US Centers for Disease Control and Prevention
Collaboration, Nonthaburi, Thailand, 4Bamrasnaradura Infectious Disease
Institute, Ministry of Public Health, Nonthaburi, Thailand, 5Centers for
Disease Control and Prevention, Atlanta, GA, United States, 6National
Institute of Health, Ministry of Public Health, Nonthaburi, Thailand
2
Samba O. Sow1, Milagritos D. Tapia2, Karen L. Kotloff2, Mariam
Sylla3, Souleymane Diallo3, Mama N. Doumbia1, Mahamadou M.
Keita1, Mamadou M. Keita3, Myron M. Levine2
1
Centre pour le Developpement des Vaccins - Mali, Bamako, Mali,
3
Hopital Gabriel Toure, Bamako, Mali
2
95
Monday, November 5
ENHANCED MICROBIOLOGY LABORATORY CAPACITY FOR
PUBLIC HEALTH MISSIONS: CHALLENGES AND SOLUTIONS IN
IMPLEMENTING STATE-OF-THE-ART TECHNOLOGY IN
SOUTHEAST ASIA
Lawrence C. Madoff
Detailed Program
www.astmh.org
4:45 p.m.
3:45 p.m.
330
SCHISTOSOMIASIS: FROM THE BENCH TO THE FIELD
TO THE BENCH
IDENTIFICATION OF ANIMAL SOURCES OF HUMAN BARTONELLOSIS IN THAILAND: COMPARISON OF BARTONELLA
SEQUENCES FROM HUMAN PATIENTS AND RODENT HOSTS
Juerg Utzinger
Zhou Xiaonong
Michael Kosoy1, Ying Bai1, Christina Morway1, Kelly Sheff1,
Leonard Peruski2, Henry Baggett2, Susan Maloney2, Saithip
Sutthirattana2, Scott Dowell3, Anussorn Sitdhirasd4, Kriangkrai
Lerdthusnee5, Jittawadee Murphy5
China CDC National Institute of Parasitic Diseases, Shanghai, China
4:30 p.m.
1
Centers for Disease Control and Prevention, Fort Collins, CO, United States,
International Emerging Infections Program, Nonthaburi, Thailand, 3Centers
for Disease Control and Prevention, Atlanta, GA, United States, 4Ministry of
Public Health, Bangkok, Thailand, 5Armed Forces Research Institute of
333
2
AMINO ACID TRANSPORT IN SCHISTOSOMES:
CHARACTERIZATION OF THE PERMEASE HEAVY
CHAIN SPRM1HC
Greice Krautz-Peterson1, Simone Camargo2, Katja Huggel2,
François Verrey2, Charles B. Shoemaker1, Patrick J. Skelly1
5 p.m.
331
1
Tufts University, North Grafton, MA, United States, 2University of Zürich,
Zürich, Switzerland
CLINICAL CHARACTERISTICS OF CONFIRMED BARTONELLA
INFECTIONS AND PREVALENCE OF BARTONELLA ANTIBODIES
AMONG PATIENTS PRESENTING TO COMMUNITY HOSPITALS
IN RURAL THAILAND
4:45 p.m.
334
Saithip Sutthirattana1, Michael Kosoy2, Anussorn Sitdhirasdr3,
Christina Morway2, Henry Baggett1, Kelly Sheff2, Scott F. Dowell4,
Tamara Fisk1, Ying Bai2, Leonard F. Peruski Jr.1
GENERATION OF AN IGG ANTI-GLYCAN MONOCLONAL
ANTIBODY, F2D2.2, THAT REACTS WITH A FUCOSE-CONTAINING EPITOPE OF SCHISTOSOMES AND CROSS-REACTS WITH
KEYHOLE LIMPET HEMOCYANIN
1
Thailand MOPH-US Centers for Disease Control and Prevention
Collaboration, Nonthaburi, Thailand, 2Centers for Disease Control and
Prevention, Fort Collins, CO, United States, 3Office of the Permanent
Secretary, Ministry of Public Health, Nonthaburi, Thailand, 4Centers for
Disease Control and Prevention, Atlanta, GA, United States
Anthony K. Nyame1, Nelum Dorabawila1, Msano Mandalasi1,
Richard D. Cummings2
1
University of Maryland Eastern Shore, Princess Anne, MD, United States,
Emory University, Atlanta, GA, United States
2
5:15 p.m.
(ACMCIP Abstract)
332
5 p.m.
GEOGRAPHIC INFORMATION SYSTEM ANALYSIS OF
BARTONELLOSIS IN AN EPIDEMIC SETTING IN CUSCO PERU
1
1
335
1
PILOT SCALE EXPRESSION AND PURIFICATION OF
SCHISTOSOMA JAPONICUM PARAMYOSIN
Hugo R. Razuri , Jesus Gonzalez , Penny Masuoka ,
Bonnie Smoak1, Scott Gordon1, Nicolle Achee1, Manuel Montoya2,
Larry Laughlin1
Mario Jiz1, Sunthorn Pond-Tor1, Mindy Reynolds2, Remigio Olveda3,
Haiwei Wu1, Luz Acosta3, Jonathan Kurtis1
1
States, 2Hospital Regional del Cusco, Cusco, Peru
1
Center for International Health Research, Rhode Island Hospital, Brown
University School of Medicine, Providence, RI, United States, 2Pathobiology
Graduate Program, Brown University, Providence, RI, United States,
3
Research Institute for Tropical Medicine, Manila, Philippines
(ACMCIP Abstract)
Schistosomiasis II - Epidemiology/Vaccine Development
Franklin 3/4
CHAIR
Jonathan D. Kurtis
Patrick Skelly
96
5:15 p.m.
www.astmh.org
Late Breakers in Basic Science/
Molecular Biology
336
Salon CD
MOLECULAR AND EVOLUTIONARY EPIDEMIOLOGY OF
SCHISTOSOMA MANSONI IN HUMAN HOSTS
Michelle L. Steinauer1, Ian J. Wilson2, Gerald M. Mkoji3,
Eric L. Agola3, Ibrahim Ndugu3, Geoffrey Maina3, Diana Karanja4,
Eric S. Loker1
This session is specifically designed for brief presentations of new data
obtained after the closing date for abstract submission. See the Late Breaker
Abstract handout in your registration packet for the presentation schedule.
1
Newcastle upon Tyne, Newcastle upon Tyne, United Kingdom, 3Kenya
Medical Research Institute, Nairobi, Kenya, 4Kenya Medical Research
Institute, Kisumu, Kenya
CHAIR
Stefan Kappe
Rebeca Rico-Hesse
Plenary Session 53
United States
Plenary Session II: Fred L. Soper Lecture
Salon GH
The Fred L. Soper Lecture is an honor bestowed on a distinguished scientist
involved in studies related to environmental control and preventive medicine
in the tropics.
Registration
CHAIR
Tuesday, November 6, 2007 7 a.m. - 5 p.m.
Robert B. Tesh
Cyber Cafe
Franklin Hall Foyer
THE RECENT EVOLUTION OF CHOLERA AND NEW STRATEGIES
FOR ITS CONTROL
David Sack
Speaker Ready Room
United States
Rooms 413-415
Poster Session A Dismantle
Franklin Hall B
Room 306
Tuesday, November 6, 2007 7 a.m. - 8 a.m.
Salon AB
ASTMH Journal Editorial Board Meeting
Room 309
This session is specifically designed for presentations of new data obtained
after the closing date for abstract submission. Presentations feature reports
of clinical trials, preliminary data on new outbreaks of disease or individual
case reports of interest. See Late Breaker Abstract handout in your registration packet for the presentation schedule.
CHAIR
Room 410
Davidson H. Hamer
Press Room
Boston University School of Public Health, Boston, MA, United States
Rooms 403-404
Barbara L. Herwaldt
Tuesday, November 6, 2007 7:30 a.m. - 6:30 p.m.
97
Tuesday, November 6
Tuesday, November 6
Monday, November 5, 2007 6 p.m. - 6:45 p.m.
www.astmh.org
Detailed Program
Symposium 54
Symposium 55
Patients Benefit from Artemether/Lumefantrine
Community Deployment
Supported with funding from Novartis Pharma AG.
Signals and Signaling in Malaria: Insights from
the Burroughs Wellcome Fund New Initiatives in
Malaria Awardees
Salon AB
Tuesday, November 6, 2007 8 a.m. - 9:45 a.m.
Salon CD
Artemether/lumefantrine is the first fixed-dose artemisinin combination therapy which was approved by stringent regulatory authorities as early as
1999. Since 2001 over 130 million treatment courses were supplied to the
public sector of malaria endemic developing countries. Twenty-eight countries have adopted artemether/lumefantrine as first-line treatment. There is
mounting evidence of significant morbidity and mortality reduction when
this ACT is included in malaria control programmes. Encouraging successes
from several African nations are reported and provide proof that rolling back
malaria and saving lives is an achievable goal.
CHAIR
Victoria P. McGovern
This session will highlight the work of four research groups that are interested in understanding the signs that tell plasmodia about the environment
within and outside the host, and the signaling processes that coordinate the
parasite’s complex group of regulatory and developmental decisions. All four
groups are awardees from the Burroughs Wellcome Fund’s New Initiatives in
Malaria program.
CHAIR
Burroughs Wellcome Fund, Research Triangle Park, NC, United States
Ambrose Talisuna
8 a.m.
8 a.m.
SECRETORY TARGETING SIGNALS IN PLASMODIA
CHANGES IN INPATIENT PEDIATRIC MALARIA CASE LOAD AT
MACHA HOSPITAL AFTER THE INTRODUCTION OF
ARTEMETHER/LUMEFANTRINE IN A RURAL ZAMBIAN
COMMUNITY
Kasturi Haldar
Philip Thuma
ROLE OF NFKB IN RESISTANCE TO MALARIA
Malaria Institute at Macha, Choma, Zambia
Chris Hunter
Northwestern University, Chicago, IL, United States
8:30 a.m.
8:20 a.m.
8:55 a.m.
COMMUNITY DEPLOYMENT OF ARTEMETHER/LUMEFANTRINE
WITH RAPID DIAGNOSTIC TESTS (RDTS) IN TIGRAY, ETHIOPIA
SIGNAL TRANSDUCTION IN MALARIA
Asefaw Getachew
Sailen Barik
Tigray Health Bureau, Tigray, Ethiopia
University of South Alabama, Mobile, AL, United States
8:40 a.m.
9:20 a.m.
LONG-TERM FOLLOW UP OF THE SOUTH AFRICAN MALARIA
CONTROL INTERVENTIONS
ACIDOCALCISOMES IN PLASMODIUM
Charlotte Muheki Zikusooka
Roberto Docampo
HealthNet Consult, Kampala, Uganda
Symposium 56
9 a.m.
THE EVALUATION OF ARTEMETHR/LUMEFANTRINE
IMPLEMENTATION IN TANZANIA (ALIVE PROJECT): KEY ISSUES
AND FIRST RESULTS
Serum Proteomics for Transfusion-Transmissible
Protozoa: Successes and Ongoing Challenges
Blaise Genton
Salon E
Ifakara Health Research and Development Center, Dar Es Salaam, United
The symposium will focus on recent work exploring serum proteomics
for a range of transfusion-transmissible protozoa including Chagas disease,
babesiosis, visceral leishmaniasis and human African trypanosomiasis.
9:25 a.m.
CHAIR
Ambrose Talisuna
Brian J. Ward
McGill University, Montreal, QC, Canada
Momar Ndao
National Reference Centre for Parasitology, Montreal, QC, Canada
98
8 a.m.
www.astmh.org
8 a.m.
344
USING SERUM PROTEOMICS TO STUDY CHAGAS DISEASE
Momar Ndao
SAFETY AND INFECTIVITY OF TETRAVALENT CHIMERIC
LIVE ATTENUATED DENGUE VACCINE IN DIFFERENT AGE
POPULATIONS IN ENDEMIC AND NON-ENDEMIC AREAS
8:20 a.m.
Dennis Morrison1, Maria Rosario Capeding2, Jorge Luis Poo3,
Remi Forrat4, Betzana Zambrano5, Anh Wartel-Tram6,
Rafaele Dumas4, Jean Lang4
PROTEOMICS-BASED TESTING FOR ACUTE BABESIOSIS
Peter J. Krause
1
Bio-Kinetic Clinical Applications, Springfield, MO, United States,
Research Institute for Tropical Health, Muntinlupa City, Philippines,
3
Centro de Investigacion Farmacologica y Biotechnologica, Mexico City,
Mexico, 4sanofi pasteur Research and Development Department, Marcy
l’Etoile, France, 5sanofi pasteur, Montevideo, Uruguay, 6sanofi pasteur,
Ho Chi Minh City, Vietnam
University of Connecticut School of Medicine, Hartford, CT, United States
2
8:35 a.m.
CAN SERUM PROTEOMICS BE USED TO ASSESS
CUTANEOUS LEISHMANIASIS
Naomi E. Aronson
8:15 a.m.
United States
345
CAN SERUM PROTEOMICS BE USED TO SCREEN BLOOD?
David Leiby
Kanakatte Raviprakash1, John Dong2, Dan Ewing1, Karla Block1,
Danher Wang2, David Holman2, Lan Chen1, Jan Woraratanadharm2,
Kevin Porter1
American Red Cross, Rockville, MD, United States
9:05 a.m.
1
Naval Medical Research Center, Silver Spring, MD, United States, 2Genphar
Inc, Mount Pleasant, SC, United States
SERUM PROTEOMICS FOR AFRICAN TRYPANOSOMIASIS
Philippe Büscher
8:30 a.m.
Tropical Medicine Institute, Antwerp, Belgium
346
9:20 a.m.
IMPROVED IMMUNOGENICITY AND PROTECTION OF
TETRAVALENT DENGUE VACCINES USING A PRIME-BOOST
STRATEGY IN NON-HUMAN PRIMATES
DISCUSSION
Brian J. Ward
Infectious Diseases, McGill University, Montreal, QC, Canada
Monika Simmons1, Michelle Ward1, Kevin Porter1, Curtis Hayes1,
Wellington Sun2, Robert Putnak3
Momar Ndao
1
Naval Medical Research Center, Silver Spring, MD, United States, 2Centers
for Disease Control and Prevention, San Juan, PR, United States, 3Walter
8:45 a.m.
347
Flavivirus III - Dengue III
Salon F
PHASE I STUDY OF THE SAFETY AND IMMUNOGENICITY OF
RDEN4Δ30-200,201 A LIVE ATTENUATED VIRUS VACCINE
CANDIDATE FOR DENGUE SEROTYPE 4
Tuesday, November 6, 2007
8 a.m. - 9:45 a.m.
CHAIR
Anna P. Durbin1, Julie H. McArthur1, Jennifer Marron1, Kimberli
Wanionek1, Bhavin Thumar1, Joseph E. Blaney2, Brian R. Murphy2,
Stephen S. Whitehead2
Anna P. Durbin
United States
1
States, 2Laboratory of Infectious Diseases, National Institutes of Health,
Bethesda, MD, United States
Wellington Sun
99
Tuesday, November 6
TETRAVALENT DENGUE VACCINE BASED ON COMPLEX
ADENOVIRUS VECTORS PROTECTS RHESUS MONKEYS
AGAINST CHALLENGE FROM ALL FOUR DENGUE SEROTYPES
8:50 a.m.
Detailed Program
www.astmh.org
9 a.m.
8 a.m.
348
PREVALENCE OF DENGUE VIRUS NUCLEIC ACID IN BLOOD
PRODUCTS DONATED IN PUERTO RICO
Hamish Mohammed1, Susan Stramer2, Kay Tomashek1, Jorge
Muñoz1, Jeff Linnen3, Lyle Petersen4
1
Dengue Branch, San Juan, Puerto Rico, 2American Red Cross, Gaithersburg,
MD, United States, 3Gen-Probe Incorporated, San Diego, CA, United States,
4
Division of Vector-Borne Infectious Diseases, Centers for Disease Control
and Prevention, Ft. Collins, CO, United States
REMOTE SENSING BASED MODELING AND SURVEILLANCE OF
MALARIA
Richard Kiang
NASA Goddard Space Flight Center, Greenbelt, MD, United States
8:25 a.m.
EBOLA RIVER HEMORRHAGIC FEVER TRIGGER EVENTS AND
SEARCHES FOR TRANSMISSION VECTORS
Compton Tucker
9:15 a.m.
349
8:50 a.m.
THE IMPACT OF INTERACTION BETWEEN SEROTYPES, AGE
STRUCTURE AND SEASONALITY ON THE TRANSMISSION
DYNAMICS OF DENGUE: A FOUR SEROTYPE MODEL
1
2
2
Laurent Coudeville , Geoff Garnett , Christl Donnelly , David
Welch3, Christine Luxemburger1
1
Sanofi Pasteur, Lyon, France, 2Imperial College, Infectious Disease
Epidemiology, London, United Kingdom, 3Imperial College, Epidemiology
and Public Health, London, United Kingdom
9:30 a.m.
350
BENCHMARKING THE INTEGRATION OF NASA EARTH SCIENCE
RESULTS
Jorge E. Pinzon
9:15 a.m.
MALARIA EARLY WARNING SYSTEM (MEWS) - GETTING
RESEARCH INTO POLICY AND PRACTICE: EXPERIENCE IN
SOUTHERN AFRICA
Stephen Conner
IRI, Columbia University, Palisades, NY, United States
ANNUAL TARGETED LARVICIDING CAMPAIGNS IN CAMBODIA
AGAINST THE DENGUE VECTOR AEDES AEGYPTI: ARE THEY
COST-EFFECTIVE?
Jose A. Suaya1, Donald S. Shepard1, Moh-Seng Chang2, Mariana
Caram1, Duong Socheat3, Michael B. Nathan4
Malaria - Diagnosis
1
Heller School, Brandeis University, Waltham, MA, United States, 2World
Health Organization Representative Office, WHO, Phnom Penh, Cambodia,
3
National Center for Parasitology, Entomology and Malaria Control, Phnom
Penh, Cambodia, 4Department of Control of Neglected Tropical Diseases,
WHO, Geneva, Switzerland
Salon H
8 a.m. - 9:45 a.m.
CHAIR
Christian Lengeler
Symposium 58
Progress Towards Predicting and Preventing Outbreaks
of Vector-Borne Disease Utilizing Satellite Remote
Sensing Technology and Models
Jacek Skarbinski
8 a.m.
337
Salon G
The symposium is designed to review and update progress in the effort to
predict and prevent vector-borne disease using remote sensing parameters.
The speakers will discuss models developed by NASA and their partners for
application of the research results for improved prevention and prediction of
outbreaks.
CHAIR
MASSIVE OVER-DIAGNOSIS OF MALARIA IN SUBSAHARAN AFRICA: TIME TO REVIEW BLANKET
TREATMENT OF UNDERFIVES
Valerie D’Acremont1, Christian Lengeler2, Blaise Genton3
1
Swiss Tropical Institute and DSM City Council City Medical Office of Health,
Dar Es Salaam, United Republic of Tanzania, 2Swiss Tropical Institute, Basel,
Switzerland, 3Swiss Tropical Institute and Ifakara Health Research and
Development Center, Dar Es Salaam, United Republic of Tanzania
John Haynes
National Aeronautics and Space Administration, Washington, DC,
United States
100
8:15 a.m.
www.astmh.org
9:15 a.m.
338
342
MALARIA RAPID DIAGNOSTIC TEST USE AND PERFORMANCE
BY FACILITY-BASED HEALTH WORKERS IN WESTERN KENYA
Alexandre Macedo de Oliveira1, Jacek Skarbinski1, Peter Ouma2,
Simon Kariuki3, John Barnwell1, Kephas Otieno3, Phillip Onyona3,
Louise Causer1, Kayla Laserson2, Willis Akhwale4, Laurence
Slutsker1, Mary Hamel2
1
Malaria Branch, Centers for Disease Control and Prevention, Atlanta, GA,
United States, 2Kenya Medical Research Institute/Centers for Disease Control
and Prevention Research Station, Kisumu, Kenya, 3Kenya Medical Research
Institute, Kisumu, Kenya, 4Division of Malaria Control, Ministry of Health,
Nairobi, Kenya
8:30 a.m.
1
Ifakara Health Research and Development Centre, Ifakara, United Republic
of Tanzania
2
9:30 a.m.
343
1
3
Jacek Skarbinski , Peter Ouma , Louise Causer , Simon Kariuki ,
John Barnwell1, Jane Alaii3, Alexandre Macedo de Oliveira1, Dejan
Zurovac4, Bruce A. Larson4, Robert W. Snow4, Alexander K. Rowe1,
Kayla Laserson2, Willis Akhwale5, Laurence Slutsker1, Mary Hamel2
Yoel Lubell1, Heidi Hopkins2, Chirstopher Whitty1, Sarah Staedke1,
Anne Mills1
1
Kingdom, 2University of California at San Francisco, San Francisco, CA,
United States
Symposium 60
1
Malaria Branch, Centers for Disease Control and Prevention, Atlanta, GA,
United States, 2Kenya Medical Research Institute/Centers for Disease Control
and Prevention Research Station, Kisumu, Kenya, 3Kenya Medical Research
Institute, Kisumu, Kenya, 4Malaria Public Health and Epidemiology Group,
Centre for Geographic Medicine, Kenya Medical Research
Institute/Wellcome Trust Research Programme, Nairobi, Kenya, 5Division of
Malaria Control, Ministry of Health, Nairobi, Kenya
8:45 a.m.
340
COMPARISON OF MICROSCOPY, HRP2- AND PLDH-BASED
RAPID DIAGNOSTIC TESTS FOR MALARIA AT SITES OF VARYING TRANSMISSION INTENSITY IN UGANDA
Heidi Hopkins1, Wilson Kambale1, Lisa Bebell2, Christian
Dokomajilar3, Sarah G. Staedke4, Moses R. Kamya5, Philip J.
Rosenthal3, Grant Dorsey3
1
MU-University of California at San Francisco Malaria Research
Collaboration, Kampala, Uganda, 2Columbia College of Physicians and
Surgeons, New York, NY, United States, 3University of California, San
Francisco, San Francisco, CA, United States, 4London School of Hygiene &
Tropical Medicine, London, United Kingdom, 5Makerere University,
Kampala, Uganda
9 a.m.
341
EVALUATION OF THE NEW MALARIA RAPID DIAGNOSTIC TEST
FIRST RESPONSE® PF/PV, WHEN USED AS A SCREENING TOOL
FOR MALARIA DURING PREGNANCY IN CENTRAL INDIA
Beyond Alma Ata: The Promise of Rural Secondary
Health Care
Salon IJ
2008 is the 30th anniversary of the signing of the Alma Ata Declaration that
launched the global commitment to “Health for All by the Year 2000”.
While substantive improvements in health have occured as a result of the
Declaration, many areas of the world are still struggling to achieve basic,
sustainable health care. This symposium will argue that, in some circumstances, “Health for All” can be best achieved through community-based
secondary health care. Following introductory comments by the chair,
speakers will first describe how a small NGO (Saludesa) in rural Ecuador,
over time, brought together diverse partners in a community of 70,000 to
create a new health center and a 15-bed hospital that delivers quality secondard health care while serving as a base for expanded, more effective primary care services. Having gradually achieved full cost-recovery and strong
support from a range of stakeholders, the current challenge, in partnership
with the Ecuadorian MOH, is to determine the degree to which this model
can be replicated within the public sector. With the 30th anniversary of the
Alma Ata Proclamation of “Health for All by 2000” approaching, the final
speaker will explore the challenges of translating into the public sector “lessons learned” by an entrepreneurial small NGO and the potential of secondary health care strategies in finally achieving the vision of Alma Ata.
CHAIR
Barnett L. Cline
Tulane University, Blanco, TX, United States
Michele Barry
P. P. Singh1, R. Ahmed2, M. P. Singh1, D. J. Terlouw2, F. O. ter
Kuile2, M. R. Desai3, V. Udhayakumar3, A. P. Dash4, N. Singh1
1
National Institute of Malaria Research, Jabalpur, India, 2Liverpool School of
Tropical Medicine, Liverpool, United Kingdom, 3Centers for Disease Control
and Prevention, Atlanta, GA, United States, 4National Institute of Malaria
Research, Delhi, India
8 a.m.
INTRODUCTION
Barnett Cline
101
Tuesday, November 6
INTRODUCTION OF MALARIA RAPID DIAGNOSTIC TESTS, NEW
GUIDELINES, AND ARTEMETHER-LUMEFANTRINE IN KENYA: A
CLUSTER RANDOMIZED TRIAL
2
Meredith McMorrow1, Irene Masanja2, S. Patrick Kachur1, Salim
M. Abdulla2
MODELLING COSTS AND BENEFITS OF RDTS FOR THE
DETECTION OF P. FALCIPARUM IN UGANDA
339
1
CHALLENGES IN ROUTINE IMPLEMENTATION AND QUALITY
CONTROL OF RAPID DIAGNOSTIC TESTS FOR MALARIA RUFIJI DISTRICT, TANZANIA
www.astmh.org
Detailed Program
8:10 a.m.
9:15 a.m.
PEDRO VICENTE MALDONADO (PVM): THE FIRST TEN YEARS
NATURAL HISTORY OF LEISHMANIA CHAGASI INFECTION IN
BRAZIL
David Gaus
Andean Health and Development (Saludesa in Ecuador), New Berlin, WI,
United States
8:35 a.m.
TRANSLATING THE PVM MODEL TO THE PUBLIC SECTOR:WHY
IT MATTERS
Michael Heisler
Selma M. Jeronimo
Universidade Federal do Rio Grande do Norte, Natal, Brazil
Clinical Tropical Medicine I
Emory University School of Medicine, Atlanta, GA, United States
Liberty AB
9 a.m.
8 a.m. - 9:45 a.m.
IS THERE A ROLE FOR SECONDARY HEALTH CARE IN
ACHIEVING THE VISION OF ALMA ATA?
CHAIR
Cynthia Haq
Menzies School of Health Research, Darwin, Australia
Anna M. Checkley
9:25 a.m.
OPEN DISCUSSION
Ric Price
8 a.m.
351
Symposium 61
Leishmaniasis: Field Studies and Treatment Trials
Salon KL
This symposium will focus on field studies and therapeutics of leishmaniasis.
Talks will address the epidemiology, clinical outcome and treatment of leishmaniasis. An update on the management of leishmaniasis in settings of
increasing report of antimonial failure will be discussed.
CHAIR
Selma M. Jeronimo
Universidade Federal do Rio Grande do Norte, Natal, Brazil
CLINICAL DIAGNOSIS OF UNCOMPLICATED MALARIA IN
OLDER CHILDREN AND ADULTS IN KENYA: AN EVIDENCE
BASE FOR NEWLY INTRODUCED GUIDELINES
Peter Ouma1, Jacek Skarbinski2, Dejan Zurovac3, Willis Akhwale4,
Kayla Laserson1, Laurence Slutsker2, Mary Hamel1
1
Kenya Medical Research Institute/Centers for Disease Control and
Prevention Research Station, Kisumu, Kenya, 2Malaria Branch, Centers for
Disease Control and Prevention, Atlanta, GA, United States, 3Malaria Public
Health and Epidemiology Group, Centre for Geographic Medicine, Kenya
Medical Research Institute/Wellcome Trust Research Programme, Nairobi,
Kenya, 4Division of Malaria Control, Ministry of Health, Nairobi, Kenya
8:15 a.m.
353
Mary E. Wilson
CLINICAL PRESENTATION OF SEVERE MALARIAL ANEMIA IN
KENYAN CHILDREN
8 a.m.
Enrico M. Novelli1, Gregory C. Davenport1, Amos K’Ogal
Omondi2, Oscar Amos Odunga2, John Michael Ong’echa2, Tom
Were2, Collins Ouma2, Richard Otieno2, James B. Hittner3, Stephen
Obaro1, Douglas J. Perkins1
CURRENT ISSUES OF CUTANEOUS LEISHMANIASIS
IN COLOMBIA
Isabel Rodriguez
Centro Internacional de Entrenamiento e Investigaciones Médicas,
Cali, Colombia
8:25 a.m.
IMMUNOMODULATORS ASSOCIATED WITH ANTIMONY
THERAPY IN THE TREATMENT OF CUTANEOUS AND
MUCOSAL LEISHMANIASIS
Edgar Marcelino Carvalho
Universidade Federal da Bahia, Salvador, Brazil
8:50 a.m.
MANAGEMENT OF VISCERAL LEISHMANIASIS IN INDIA
Shyam Sundar
1
University of Pittsburgh, Pittsburgh, PA, United States, 2University of
Pittsburgh/KEMRI Laboratories of Parasitic and Viral Diseases, Kisumu,
Kenya, 3College of Charleston, Charleston, SC, United States
8:30 a.m.
354
P. VIVAX INFECTION: A MAJOR DETERMINANT OF SEVERE
ANAEMIA IN PAPUA, INDONESIA
R.N. Price1, E. Tjitra2, M. Karyana2, N.M. Warikar3, E. Kenangalem4,
D.A. Lampah3, P. Sugiarto5, N.M. Anstey1
1
Menzies School of Health Research, Darwin, Australia, 2National Institute of
Health Research and Development, Jakarta, Indonesia, 3International Health
Program, Timika, Indonesia, 4District Health Authority, Timika, Indonesia,
5
Mitra Masyarakat Hospital, Timika, Indonesia
Banaras Hindu University, Varanasi, India
102
8:45 a.m.
www.astmh.org
8 a.m.
355
358
AN ASSESSMENT OF THE MANAGEMENT OF SEVERE
MALARIA IN ZAMBIAN HEALTH FACILITIES
FAMILIAL AGGREGATION OF ACUTE LYMPHATIC FILARIASIS IN
PAPUA NEW GUINEA
Pascalina Chanda1, James Chipeta2, Mutale Chimutete3, Micky
Ndhlovu4, Charles Msiska5, Mabvuto Kango6, Abel Kabalo7, Busiku
Hamainza1, Pauline Wamulume1, Allison C. Kennedy8
Daniel J. Tisch1, Edsel Salvana2, Will Kastens1, Moses Bockarie1,
Neal Alexander3, James W. Kazura1
1
National Malaria Control Centre, Lusaka, Zambia, 2University Teaching
Hospital, Paediatrics Department, Lusaka, Zambia, 3Gwembe District Office,
Gwembe, Zambia, 4Chainama Hills College Hospital, Lusaka, Zambia,
5
Chongwe District Health Office, Chongwe, Zambia, 6Ministry of Health,
Lusaka, Zambia, 7Kabwe District Office, Kabwe, Zambia, 8Monze District
Office, Monze, Zambia
Hospitals, Cleveland, OH, United States, 3London School of Tropical
Medicine and Hygiene, London, United Kingdom
8:15 a.m.
359
A RAPID HEALTH IMPACT ASSESSMENT OF THE AFRICAN
PROGRAMME FOR ONCHOCERCIASIS CONTROL (APOC)
356
WHY DOES IMPORTED MALARIA STILL KILL? TWENTY YEARS
OF MALARIA DEATHS IN THE UNITED KINGDOM
Anna M. Checkley1, Adrian D. Smith2, Marie Blaze3, Valerie
Smith3, Peter L. Chiodini3, Christopher J. Whitty3
Wilma A. Stolk, Lennert J. Veerman, Sake J. de Vlas,
J. Dik Habbema
Department of Public Health, Erasmus MC, Rotterdam, The Netherlands
8:30 a.m.
360
2
Hospital for Tropical Diseases, London, United Kingdom, Department of
Public Health, University of Oxford, Oxford, United Kingdom, 3Malaria
Reference Laboratory, London, United Kingdom
HAS EGYPT ELIMINATED LYMPHATIC FILARIASIS?
Reda M. Ramzy1, Maged El Setouhy1, Hanan Helmy1, Hoda A.
Farid1, Adel M. Gad1, Gary J. Weil2
9:15 a.m.
357
CLINICAL DEVELOPMENT OF NEW PROPHYLACTIC ANTIMALARIAL DRUGS AFTER THE FIFTH AMENDMENT TO THE
DECLARATION OF HELSINKI
1
Research and Training Center on Vectors of Disease, Ain Shams University,
Cairo, Egypt, 2Infectious Diseases Division, Washington University School of
Medicine, St. Louis, MO, United States
8:45 a.m.
361
Geoffrey S. Dow, Alan Magill, Wil Milhous, Colin Ohrt
Filariasis I - Epidemiology/Molecular Biology
Liberty C
8 a.m. - 9:45 a.m.
CHAIR
Maged El-Setouhy
GRAVID TRAP COLLECTIONS OF CULEX PIPIENS FOR MOLECULAR XENOMONITORING NATIONAL PROGRAMS FOR ELIMINATION OF LYMPHATIC FILARIASIS
Adel M. Gad1, Reda M. Ramzy1, Hanan Helmy1, Ragaa E.
Hammad1, Zakariya S. Morsy1, Sherin A. Kamal1, Mohamed F.
Salam1, Maged El Setouhy1, Gary J. Weil2, Hoda A. Farid1
1
Research and Training Center on Vectors of Diseases, Ain Shams University,
Cairo, Egypt, 2Washington Unversity School of Medicine, St. Louis, MO,
United States
9 a.m.
362
Ain Shams University, Cairo, Egypt
Sandra Laney
Smith College, Northampton, MA, United States
DIFFERENTIAL EUKARYOTIC GENE EXPRESSION IN
ONCHOCERCA VOLVULUS (WITH A WOLBACHIA ENDOSYMBIONT) AND O. FLEXUOSA (WOLBACHIA NEGATIVE)
Peter Fischer1, Norbert W. Brattig2, Samantha N. Piper1, Kerstin
Fischer1, Seth D. Crosby1, Makedonka Mitreva1, Michael Heinz1,
Yin Yong1, Gary J. Weil1
1
Washington University School of Medicine, St. Louis, MO, United States,
Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany
2
103
Tuesday, November 6
9 a.m.
1
1
Detailed Program
www.astmh.org
9:15 a.m.
9:20 a.m.
363
CIS ACTING ELEMENTS NECESSARY FOR TRANS-SPLICING IN
TRANSIENTLY TRANSFECTED BRUGIA MALAYI
Ana de Oliveira, Canhui Liu, Tarig B. Higazi, Thomas R. Unnasch
CHARACTERIZING EFFECTOR CELLS AT THE HOST:
PARASITE INTERFACE
William Gause
University of Medicine and Dentistry of New Jersey-New Jersey Medical
School, Newark, NJ, United States
(ACMCIP Abstract)
9:30 a.m.
QUESTION AND ANSWER PERIOD OR LATE BREAKER
ABSTRACT PRESENTATION
Symposium 65
Costing Large-Scale Vector Control Programmes in SubSaharan Africa
Franklin 2
Symposium 64
Immuno-Regulation of Parasitic Infections in the Gut
Franklin 1
There is an increasing appreciation for the unique properties of immunity
generated at mucosal sites. The gastrointestinal tract is in constant contact
with food proteins, commensal bacteria and potentially pathogenic microorganisms. In order to maintain immune homeostasis in this environment, the
intestinal immune system has evolved multiple regulatory strategies, including various populations of regulatory T cells and specialized subset of dendritic cells or macrophages. Orally ingested parasites are primarily exposed
to this unique immunological system and benefit from it in order to favor
their survival and transmission. Therefore, in the design of new therapeutic
strategies or vaccines, it is necessary to consider the endogenous regulatory
mechanisms that are operating in the gut. This session will highlight new
studies that are extending our understanding of how immunity and inflammation are regulated following exposure to gastrointestinal parasites.
A vigorous debate is currently going on about the best way to provide
large-scale vector control in Sub-Saharan Africa. Unfortunately, little of this
has been based on solid standardized evidence. This symposium presents a
substantial new body of data on costs and operational implications of largescale vector control interventions using (1) Insecticide-Treated Nets (ITNs) or
(2) Indoor Residual Spraying (IRS). Case studies will also provide cost-effectiveness (CE) estimates. The aim of the session will be to critically review
these standardized findings and to discuss their implications for the planning of national-scale vector control programmes in sub-Saharan Africa.
CHAIR
Christian Lengeler
Kara Hanson
8 a.m.
CHAIR
INTRODUCTION
David Artis
Christian Lengeler
Yasmine Belkaid
8:20 a.m.
8 a.m.
REGULATORY T CELL FUNCTION IN THE GUT
COSTING ASSESSMENTS - AN OVERVIEW
Kara Hanson
Yasmine Belkaid
8:40 a.m.
National Institutes of Health, National Institute of Allergy and Infectious
Diseases, Maryland, MD, United States
COSTING INTEGRATED VECTOR CONTROL ON BIOKO ISLAND
(EQUATORIAL GUINEA)
8:30 a.m.
Chris Schwabe
IL-10-MEDIATED REGULATION OF INTESTINAL AMEBIASIS
Medical Care and Development International, Silver Spring, MD, United
States
Eric Houpt
9 a.m.
University of Virginia, Charlottesville, VA, United States
COSTING RECENT IRS PROGRAMMES IN SUB-SAHARAN
AFRICA
8:55 a.m.
EPITHELIAL CELL-DENDRITIC CELL CROSS-TALK REGULATES
INTESTINAL IMMUNITY AND INFLAMMATION
Eugene Brandly
Research Triangle International, Washington, DC, United States
David Artis
104
www.astmh.org
9:20 a.m.
9:30 a.m.
COMPARATIVE COSTS AND COST-EFFECTIVENESS OF FIVE
NATIONAL ITN PROGRAMMES AND TWO LARGE IRS PROGRAMMES
COST EFFECTIVENESS, INTEGRATION AND SUSTAINABILITY OF
SCHISTOSOMIASIS CONTROL IN UGANDA
Joshua Yukich
Narcis Kabatereine
Exhibit Hall Open
Franklin Hall B
Advances in Operational Research on Schistosomiasis
Tuesday, November 6, 2007 9:30 a.m. - 10:30 a.m.
Franklin 3/4
Coffee Break
In 206, the Schistosomiasis Research Program at the DBL-Center for Health
Research and Development awarded funds to support operational research
addressing schistosomiasis in endemic African countries. This was part of a
broad effort to develop the basis for sustained schistosomiasis control and
evidence for policy decisions at the national and international level. This symposium will share the results of some of the funded projects. The presentations will address the issue of anemia due to schistosomiasis in school-aged
African children, the benefits of iron supplementation in helminth control
programs, evaluation of urine based diagnosis of S. mansoni, and assessment
of the cost effectiveness of a national schistosomiasis control program.
CHAIR
Gitte Rohde
The Schistosomiasis Research Program, Charlottenlund, Denmark
Alan Fenwick
Franklin Hall B
Tuesday, November 6, 2007 9:45 a.m. - 10:15 a.m.
Poster Session B Set-Up
Franklin Hall B
9:45 a.m. - 10:15 a.m.
Franklin Hall B
10:15 a.m. - Noon
The Schistosomiasis Control Initative, London, United Kingdom
8 a.m.
Malaria - Molecular Biology
INTRODUCTION
Salon AB
Alan Fenwick
10:15 a.m. - Noon
8:15 a.m.
ASSESSMENT OF ANEMIA ATTRIBUTABLE TO SCHISTOSOMIASIS
Diana Karanja
8:40 a.m.
EVALUATION OF APPLICABILITY OF URINE BASED SCHISTOSOMIASIS TEST STRIP IN THE EPIDEMIOLOGICAL MAPPING AND
SAMPLING OF S. MANSONI INFECTION IN LOW ENDEMIC
AREAS OF KENYA
CHAIR
Ahmed S. Aly
Heather J. Painter
10:15 a.m.
364
Jimmy Kihara
PLASMODIUM SPOROZOITES LACKING AN ASPARAGINE RICH
PROTEIN FAIL TO ESTABLISH LIVER STAGE INFECTION AND
ELICIT STERILE IMMUNITY AGAINST MALARIA
Ministry of Health, Nairobi, Kenya
Ahmed S. Aly, Stefan H. Kappe
9:05 a.m.
IRON SUPPLEMENTATION IN SCHISTOSOMIASIS AND SOIL
TRANSMITTED HELMINTHS CONTROL PROGRAM IN ZAMBIA
(ACMCIP Abstract)
Victor Mwanakasale
Tropical Diseases Research Centre, Ndola, Zambia
105
Tuesday, November 6
Symposium 66
Detailed Program
www.astmh.org
10:30 a.m.
11:45 a.m.
365
TO LIVE OR DIE: INVESTIGATING THE ROLE OF PLASMODIUM
FALCIPARUM MITOCHONDRIA IN THE FACE OF ELECTRON
TRANSPORT INHIBITION
Heather J. Painter, Joanne M. Morrisey, Akhil B. Vaidya
(ACMCIP Abstract)
10:45 a.m.
366
CHARACTERIZATION OF MOLECULAR EVENTS OF
AUTOPHAGY IN PLASMODIUM FALCIPARUM
Mayumi Akaki, Timothy G. Schneider, Theodore F. Taraschi
11 a.m.
367
HOST LIPOATE IS REQUIRED FOR MALARIA SURVIVAL
370
COMPREHENSIVE PROTEOMIC ANALYSIS OF ZYGOTE AND
OOKINETE STAGES OF AVIAN PLASMODIUM REVEALS
ORTHLOGS OF THE UNKNOWN EARLY MOSQUITO STAGES OF
PLASMODIUM FALCIPARUM
Kailash P. Patra1, Greg T. Cantin2, Jeff R. Johnson2, John R. Yates2,
Joseph M. Vinetz1
1
Department of Medicine, University of California San Diego, La
Jolla, CA, United States, 2The Scripps Research Institute,
Department of Cell Biology, La Jolla, CA, United States
Symposium 68
Global Health Symposium on Tropical Medicine
Supported with funding from the Bill and Melinda Gates
Foundation
Salon CD
Tuesday, November 6, 2007 10:15 a.m. – Noon
This symposium features young investigators from Cameroon, Kenya and
Uganda who have received travel awards to present their work on malaria
at the annual meeting.
(ACMCIP Abstract)
CHAIR
11:15 a.m.
James LeDuc
Sean T. Prigge, Marina Allary, Jeff Lu, Liqun Zhu
368
GENOTYPING ANALYSIS OF P. FALCIPARUM REVEALS
GREATER GENETIC DIVERSITY IN SENEGAL COMPARED TO
THAILAND AND POPULATION DIFFERENCES ENRICHED FOR
AMINO ACID SUBSTITUTIONS
Sarah K. Volkman1, Daniel E. Neafsey2, Pardis C. Sabeti2, Daniel J.
Park2, Stephen J. Schaffner2, Danny A. Milner1, Amanda Lukens1,
Phil Montgomery2, Casey Gates2, Nathan Houde2, Johanna P. Daily1,
Ousmane Sarr3, Douda Ndiaye3, Soulyemane Mboup3, Roger
Wiegand2, Daniel L. Hartl4, Bruce W. Birren2, James E. Galagan2,
Eric S. Lander2, Dyann F. Wirth1
Harvard School of Public Health, Boston, MA, United States, 2Broad
Institute of MIT and Harvard, Cambridge, MA, United States, 3Cheikh Anta
Diop University, Dakar, Senegal, 4Harvard University, Cambridge, MA, United
States
Regina Rabinovich
10:15 a.m.
INTRODUCTION
Regina Rabinovich
10:30 a.m.
865
1
(ACMCIP Abstract)
INCREASED TOLERANCE TO PYRETHROIDS IN ANOPHELES
ARABIENSIS DURING COTTON SPRAYING IN NORTH
CAMEROON: EVIDENCE FOR CONSTITUTIVE OVER-EXPRESSION OF ANTIOXIDANT DEFENSES
11:30 a.m.
Mouhamadou S. Chouaibou1, Pie Müller2, Josiane Etang3, Martin
Donnelly2, Hilary Ranson2, Frédéric Simard4
369
DISTINCT PHYSIOLOGICAL STATES OF THE PARASITE
PLASMODIUM FALCIPARUM IN MALARIA INFECTED PATIENTS
Johanna P. Daily1, Dan Scanfeld2, Nathalie Pochet2, Karine Le
Roch3, David Plouffe4, Michael Kamal2, Ousmane Sarr5, Souelyman
Mboup5, Omar Ndir5, David Wypij1, Kathryn Levasseur1, Elizabeth
Thomas2, Pablo Tamayo2, Carolyn Dong1, Yingyao Zhou4, Eric
Lander2, Daouda Ndiaye5, Elizabeth Winzeler6, Jill Mesirov2,
Aviv Regev2
1
Organisation de Coordination pour la lutte contre les Endémies en Afrique
Centrale (OCEAC), Université de Yaoundé I (UYI), Institut de Recherche pour
le dévéloppement (IRD), Yaoundé, Cameroon, 2Liverpool School of Tropical
Medicine and Hygien, Liverpool, United Kingdom, 3Organisation de
Coordination pour la lutte contre les Endémies en Afrique Centrale
(OCEAC), Yaoundé, Cameroon, 4IRD/UR016, Montpellier, France;
Organisation de Coordination pour la lutte contre les Endémies en Afrique
Centrale (OCEAC), Yaoundé, Cameroon
1
Institute of Harvard and MIT, Cambridge, MA, United States, 3University of
California, Riverside, CA, United States, 4Genomics Institute of Novartis
Research Foundation, San Diego, CA, United States, 5Cheikh Anta Diop
University, Dakar, Senegal, 6Scripps Institute, La Jolla, CA, United States
106
11:45 a.m.
1035
PANEL DISCUSSION
SPATIAL MODELLING OF HABITAT SUITABILITY, DISTRIBUTION,
AND RELATIVE ABUNDANCE OF SPECIES AND MOLECULAR
FORMS OF THE ANOPHELES GAMBIAE COMPLEX IN CAMEROON
Symposium 69
Colince D. Kamdem1, Joachim Etouna2, Kenji Ose3, Diego Ayala4,
Nora J. Besansky5, Didier Fontenille4, Carlo Costantini6, Frédéric
Simard7
1
Organisation de Coordination pour la lutte Contre les Endémies en Afrique
Centrale (OCEAC) and University of Yaounde I, Yaounde, Cameroon,
2
Institut National de Cartographie (INC), Yaounde, Cameroon, 3Institut de
Recherche pour le Développement (IRD), US140, Orleans, France, 4Institut
de Recherche pour le Développement (IRD), UR016, Montpellier, France,
5
Department Biological Sciences, University Notre Dame, Notre Dame, IN,
United States, 6Institut de Recherche pour le Développement (IRD)-UR016;
and Institut de Recherche en Sciences de la Santé (IRSS), Bobo-Dioulasso,
Burkina Faso, 7Institut de Recherche pour le Développement (IRD)-UR016,
and Organisation de Coordination pour la lutte Contre les Endémies en
Afrique Centrale (OCEAC), Yaounde, Cameroon
11 a.m.
1026
DISCRIMINATIVE FEEDING BEHAVIOR OF ANOPHELES GAMBIAE S.S ON DIFFERENT PLANT SPECIES AND EFFECTS ON ITS
SURVIVAL, FECUNDITY, AND VECTOR COMPETENCE IN A
MALARIA ENDEMIC AREA OF WESTERN KENYA
Hortance Manda1, Louis C. Gouagna2, Ephantus W. Kabiru3,
Woodbridge A. Foster4, John C. Beier5, Ahmed Hassanali1, John I.
Githure1
1
International Centre of Insect Physiology and Ecology, Nairobi, Kenya,
Institut de Recherche pour le Développement (IRD), Ouagadougou, Burkina
Faso, 3Department of Pathology, Kenyatta University, Nairobi, Kenya,
4
Department of Entomology, The Ohio State University, Columbus, OH,
United States, 5Department of Epidemiology and Public Health, University of
Miami, Miami, FL, United States
2
11:15 a.m.
694
Implementation of a New ACT in African Endemic
Countries: Opportunities and Challenges for
Documenting Safety and Effectiveness in the Field
Supported with funding from sanofi aventis
Organizational support provided by DNDi
Salon E
Tuesday, November 6, 2007 10:15 a.m. - Noon
The launch of a new drug, such as a new Artemisinin-based Combination
Therapy (ACT), requires monitoring of its safety and efficacy in “real life”
conditions, to detect issues that could not be identified during clinical development studies. In most African countries, pharmacovigilance systems are
absent, nascent or poorly functional. The symposium will discuss innovative
ways to gather good quality safety and effectiveness data on new ACTs, and
how these initiatives can help build, over time, effective pharmacovigilance
systems across Africa.
CHAIR
Wilfred F. Mbacham
University of Yaoundé, Cameroon, Yaoundé, Cameroon
10:15 a.m.
CHALLENGES AND OPPORTUNITIES OF PHARMACOVIGILANCE
IN SUB-SAHARAN AFRICA
Alexander Dodoo
University of Ghana Medical School, Accra, Ghana
10:45 a.m.
COLLECTION OF ACT EFFECTIVENESS AND RESISTANCE DATA
IN UGANDA
Ambrose Talisuna
ROLE OF IL-10 AND HEMOZOIN IN REGULATING IL-12 AND
IL-17 PATHWAYS IN KENYAN CHILDREN WITH SEVERE
MALARIAL ANEMIA
Uganda Ministry of Health, Kampala, Uganda
John Michael Ong'echa1, Gregory Davenport2, Yamo Ouma1,
James Hittner3, Tom Were1, Collins Ouma1, Richard Otieno1,
Christopher Keller4, John Vulule5, Gordon Awandare2, Douglas Perkins2
DATA COLLECTION ON THE USE OF ACTS IN PREGNANCY
1
Pittsburgh, PA, United States, 3College of Charleston, Charleston, SC, United
States, 4University of Pittsburgh/Lake Erie College of Ostepathic Medicine,
Pittsburgh, PA, United States, 5KEMRI, Kisumu, Kenya
11:30 a.m.
11:10 a.m.
Francois Nosten
Shoklo Malaria Research Unit, Mae Sot, Thailand
11:35 a.m.
OPPORTUNITIES FOR THE COLLECTION OF ACT SAFETY DATA
IN THE FIELD: PROS AND CONS OF VARIOUS APPROACHES
Umberto D’Alessandro
352
Prince Leopold Institute of Tropical Medicine, Antwerp, Belgium
PREDICTORS OF ANTICONVULSANT TREATMENT FAILURE
AMONG CHILDREN WITH SEVERE MALARIA
Arthur Mpimbaza1, Sarah Staedke2, Grace Ndeezi1, Justus
Byarugaba1, Philip J. Rosenthal3
1
Makerere University, Kampala, Uganda, 2London School of Hygiene and
Tropical Medicine, London, United Kingdom, 3University of California San
107
Tuesday, November 6
10:45 a.m.
www.astmh.org
www.astmh.org
Detailed Program
Symposium 70
12:10 p.m.
OUTBREAK REPORTS
American Committee on Arthropod-Borne Viruses
(ACAV): Modulation of Innate Immune Responses in
Vertebrate and Arthropod Host Cells By Arboviruses
Douglas M. Watts
Salon F
Symposium 71
Tuesday, November 6, 2007 10:15 a.m. - 12:45 p.m.
Vertebrates and invertebrates have developed sophisticated methods to
recognize and defend themselves from a variety of pathogens. These
aspects of defense, often referred to as innate immunity, operate at both
the cellular and organismal levels. Many pathogens, notably the RNA
viruses, have developed countermeasures to overcome the host or host
cell response to infection. This symposium will provide some of the more
recent findings regarding the mechanisms/strategies identified during
infections of vertebrate or invertebrate hosts and that play a major role in
the outcome of infection.
CHAIR
Douglas M. Watts
10:15 a.m.
ACAV BUSINESS MEETING AND AWARDS PRESENTATION
Douglas M. Watts
10:45 a.m.
World Antimalarial Resistance Network: Steps to
Implementation
Salon G
This symposium will outline the plans to create a worldwide network to
monitor antimalarial drug resistance, and to create an open access Webbased interface for analysis and presentation of antimalarial drug efficacy.
CHAIR
Carol Hopkins Sibley
10:15 a.m.
ASSESSMENT OF CLINICAL EFFICACY OF ANTIMALARIAL
DRUGS
Richard Price
Menzies School of Health Research and Charles Darwin University,
Darwin, Northern Territory, Australia
SYMPOSIUM INTRODUCTION
10:35 a.m.
Douglas M. Watts
ASSESSMENT OF EFFICACY OF ANTIMALARIAL DRUGS
IN VITRO
10:50 a.m.
Dennis E. Kyle
University of South Florida, Tampa, FL, United States
THE EARLY INNATE IMMUNE HOST DEFENSE RESPONSE
AGAINST WEST NILE VIRUS
10:50 a.m.
Michael Diamond
Washington School of Medicine, St. Louis, MO, United States
11:10 a.m.
RNA INTERFERENCE AS AN INNATE ANTIVIRAL RESPONSE TO
ARBOVIRUSES IN MOSQUITOES
Carol Blair
Colorado State University, Ft. Collins, CO, United States
11:30 a.m.
THE ROLE OF MOLECULAR MARKERS IN SURVEILLANCE FOR
ANTIMALARIAL DRUG EFFICACY
11:05 a.m.
THE ROLE OF PHARMACOLOGY IN ASSESSMENT OF
ANTIMALARIAL DRUG EFFICACY
Nicholas J. White
Mahidol University, Bangkok, Thailand
THE ROLE OF VIRAL N-LINKED GLYCANS IN ALPHAVIRUS
IMMUNE EVASION AND IMMUNE PATHOLOGY
11:20 a.m.
Mark Heise
DISCUSSION
University of North Carolina, Chapel Hill, NC, United States
11:50 a.m.
WHY IS EBOLA VIRUS SO PATHOGENIC? INHIBITION OF
INNATE IMMUNITY BY THE VP35 PROTEIN
Amy Hartman
108
Symposium 72
www.astmh.org
10:15 a.m.
371
Salon H
Clinical symposium oriented towards practitioner evaluating and
treating skin lesions in expatriates, immigrants and returning travellers
in developed countries.
CHAIR
Winnie Ooi
Tufts University School of Medicine, Burlington, MA, United States
10:15 a.m.
NATURAL HISTORY OF HYDATID INFECTION AND DISEASE
Saul J. Santivañez1, Silvia Rodriguez2, Mary L. Rodriguez1, Juan G.
Aguinaga3, Ivy M. Renteria4, Cesar Gavidia5, Hector H. Garcia1, For
the Cysticercosis Working Group in Peru1
1
Department of Microbiology, Universidad Peruana Cayetano Heredia,
School of Sciences, Lima, Peru, 2Cysticercosis Unit, Instituto de Ciencias
Neurológicas, Lima, Peru, 3School of Medicine, Universidad Nacional Mayor
de San Marcos, Lima, Peru, 4School of Medicine, Universidad San Martin de
Porras, Lima, Peru, 5School of Veterinary Medicine, Universidad Nacional
Mayor de San Marcos, Lima, Peru
10:30 a.m.
372
UPDATE ON LEPROSY
Tufts University School of Medicine, Burlington, MA, United States
STRAIN CHARACTERISATION OF HUMAN HYDATIDOSIS IN
SUDAN
10:45 a.m.
Rihab A. Omer1, Anke Dinkel2, Thomas Romig2, Ute
Mackenstedt2, Mohamed Elamin3, Ayman Elnahas4, Imad Aradaib4
Winnie Ooi
Walter Reed Army Institute of Research, Bethesda, MD, United States
1
Central Veterinary Research Laboratories, Khartoum, Sudan, 2Institute of
Parasitology. University of Hohenehim, Stuttgart, Germany, 3Elshab Teaching
Hospital, Khartoum, Sudan, 4Faculty of Veterinary Medicine, University of
Khartoum, Khartoum, Sudan
11:10 a.m.
10:45 a.m.
TROPICAL ETHNODERMATOLOGY
Scott Norton
CLINICAL AND IMMUNOLOGICAL ASPECTS OF AMERICAN
CUTANEOUS LEISHMANIASIS IN BRAZIL
Paulo R. Machado
Universidade Federal da Bahia, Salvador, Brazil
11:35 a.m.
FEVER AND RASH IN THE RETURNED TRAVELLER
Carrie Kovarik
Intestinal and Tissue Helminths II: Echinococcosis
Salon IJ
10:15 a.m. - Noon
CHAIR
Bruno Gottstein
University of Bern Institute of Parasitology, Bwern, Switzerland
373
PAIR IN BULGARIA: A FIVE-YEAR EXPERIENCE
Branimir Golemanov1, Enrico Brunetti2, Nikola Grigorov3, Rumiana
Mitova3, Jordan Genov3, Dimitar Vuchev4
1
Clinical Centre of Gastroenterology, University Hospital “Queen Giovanna”,
Sofia, Bulgaria, 2University of Pavia , S.Matteo Hospital Foundation, Pavia,
Italy, 3Clinical Centre of Gastroenterology, University Hospital “Queen
Giovanna”, Sofia, Bulgaria, 4National Centre of Infectious and Parasitic
Diseases, Sofia, Bulgaria
11 a.m.
374
LONG-TERM SONOGRAPHIC AND SEROLOGICAL FOLLOW-UP
OF INACTIVE ECHINOCOCCAL CYSTS OF THE LIVER
Enrico Brunetti1, Federica Castelli2, Antonella Grisolìa2, Giuseppe
Mariani2, Carlo Filice1
1
University of Pavia, S.Matteo Hospital Foundation, Pavia, Italy, 2University of
Pavia, Pavia, Italy
11:15 a.m.
375
Peter Kern
University of Ulm, Ulm, Germany
CLOSE CORRELATION OF CLINICAL REGRESSION AND SPECIFIC
SEROLOGY IN THE FOLLOW-UP OF PATIENTS WITH ALVEOLAR
ECHINOCOCCOSIS
Dennis Tappe1, Yasuhito Sako2, Sonoyo Itoh2, Matthias Frosch1,
Beate Gruener3, Stefan Reuter3, Minoru Nakao2, Akira Ito2,
Peter Kern3
1
Institute of Hygiene and Microbiology, University of Wuerzburg,
Wuerzburg, Germany, 2Department of Parasitology, Asahikawa Medical
College, Asahikawa, Japan, 3Division of Infectious Diseases, University
Hospital and Medical Center Ulm, Ulm, Germany
109
Tuesday, November 6
Tropical Dermatology for the Clinician
Detailed Program
www.astmh.org
11:30 a.m.
11:10 a.m.
376
CHARACTERIZATION OF THE IN VITRO ACTIVITIES OF
ARTEMISININ-DERIVATIVES AGAINST ECHINOCOCCUS MULTILOCULARIS METACESTODES
Martin Spicher1, Jennifer Keiser2, Andrew Hemphill1
1
University of Berne, Berne, Switzerland, 2Swiss Tropical Institute, Basel,
Switzerland
MEMORY CD8+ T CELLS IN CHAGAS DISEASE
Rick L. Tarleton
11:35 a.m.
MEMORY TH2 CELLS INDUCED BY
GASTROINTESTINAL NEMATODES
Markus Mohrs
11:45 a.m.
Trudeau Institute, Saranac Lake, NY, United States
377
MICROSATELLITE POLYMORPHISM AS A TOOL TO STUDY THE
SPATIAL DISTRIBUTION OF ECHINOCOCCUS MULTILOCULARIS
Bruno Gottstein1, Jenny Knapp2, Jean-Mathieu Bart2, Stephan
Maillard2, Renaud Piarroux2
1
Clinical Tropical Medicine II
Liberty AB
Institute of Parasitology, Bern, Switzerland, 2Parasitology Department,
Besancon, France
10:15 a.m. - Noon
(ACMCIP Abstract)
CHAIR
Symposium 74
David J. Bell
University of Liverpool, Liverpool, United Kingdom
Memory T Cell Development During Acute and Chronic
Parasitic Infections
Walter Taylor
Salon KL
10:15 a.m.
Oxford University, Hanoi, Vietnam
378
This symposium will focus on experimental systems utilizing protozoan and
helminth infections to understand the development and maintenance of
memory T cells. This symposium will be timely given recent advances in our
understanding of the behavior of T cells as immunologic memory develops.
Presenters will be asked to link their experimental results to published data
from human studies in order to provide a framework for discussion of the
possible translation of findings from the laboratory to advances in the field.
COMBINATION LIPOSOMAL AMPHOTERICIN B (AMBISOME®,
AMB) AND MILTEFOSINE (MF) FOR THE TREATMENT OF VISCERAL LEISHMANIASIS (VL) IN NORTHERN BIHAR, INDIA
Shyam Sundar1, P. Olliaro2, M. Rai1, J. Chakravarty1, D. Agrawal1,
N. Agrawal1, M. Vaillant3, H. W. Murray4
1
Institute of Medical Sciences, Banaras Hindu University, Varanasi, India,
UNICEF/UNDP/WB/WHO Special Programme for Research and Training in
Tropical Diseases (TDR), Geneva, Switzerland, 3Centre for Health Studies,
CRP-Santé, Luxembourg, Luxembourg, 4Department of Medicine, Weill
Cornell Medical College, New York, NY, United States
2
CHAIR
Phillip Scott
University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA,
United States
Edward Pearce
United States
10:15 a.m.
MEMORY T CELLS IN LEISHMANIASIS IN THE PRESENCE AND
ABSENCE OF PERSISTENT PARASITES
Phillip Scott
University of Pennsylvania School of Veterinary Medicine, Philadelphia,
United States
10:30 a.m.
379
WHAT BASELINE PATIENT CHARACTERISTICS PREDICT TOXICITY DURING SODIUM STIBOGLUCONATE TREATMENT?
Naomi E. Aronson1, Glenn Wortmann2, Janelle Rhorer3, Joel
Verter3, David Shoemaker4, Clifton Hawkes2, Walter Reed Clinical
Leishmaniasis Group2
1
States, 2Walter Reed Army Medical Center, Washington, DC, United States,
3
Statistics Collaborative, Washington, DC, United States, 4U.S. Army Medical
Research Institute of Infectious Diseases, Fort Detrick, MD, United States
10:45 a.m.
MEMORY T CELLS IN CHRONIC SCHISTOSOMIASIS
Edward Pearce
United States
110
10:45 a.m.
www.astmh.org
11:45 a.m.
380
384
Alon Unger1, Seth O’Neal2, Luiz H. Guimarães3, Paulo R.
Machado3, Leda Alcantara4, Daniel J. Morgan5, Sara Passos3, Edgar
M. Carvalho3
1
University of California, Los Angeles, Los Angeles, California, CA, United
States, 2Oregon Health Sciences University, Portland, OR, United States,
3
Hospital Universitário Professor Edgard Santos, Salvador, Brazil,
4
Universidade da Bahia, Salvador, Brazil, 5Weill Medical College of Cornell
11 a.m.
381
SEROPREVALENCE OF TOXOCARIASIS IN SCHOOLCHILDREN IN
SAN JUAN DE LURIGANCHO, LIMA, PERU
Judith P. Breña1, Ciro P. Maguiña1, Leandro Huayanay2, Roger
Hernandez1, Yrma Espinoza3, William H. Roldan3
1
Institute of Tropical Medicine “Alexander von Humboldt”, Universidad
Peruana Cayetano Heredia, Lima, Peru, 2Unit of Clinical Epidemiology,
Universidad Peruana Cayetano Heredia, Lima, Peru, 3Institute of Tropical
Medicine “Daniel Alcides Carrion”, Universidad Nacional Mayor de San
Marcos, Lima, Peru
A PHASE II VACCINE TRIAL OF MENINGOCOCCAL A
CONJUGATE VACCINE (PSATT) IN AFRICAN TODDLERS
Samba O. Sow1, Brown Okoko2, Marie-Pierre Preziosi3, Elisa
Marchetti4, Milagritos D. Tapia5, Fadima C. Haidara1, Richard
Adegbola2, Ray Borrow6, George Carlone7, Adebayo Akinsola2,
Souleymane Diakite1, Varsha Parulekar8, Brian Plikaytis7, Helen
Findlow6, Cheryl Elie7, Jean-Marie Preaud4, Subash Kapre9, Suresh
Jadav9, Marc LaForce4, Prasad Kulkarni9, Simonetta Viviani4
1
Centre pour le Developpement des Vaccins - Mali, Bamako, Mali, 2Medical
Research Council, Basse, Gambia, 3Meningitis Vaccine Project, Initiative for
Vaccine Research, WHO, Geneva, Switzerland, 4Meningitis Vaccine Project,
PATH, Ferney-Voltaire, France, 5University of Maryland School of Medicine,
Baltimore, MD, United States, 6Health Protection Agency, Manchester,
United Kingdom, 7Centers for Disease Control and Prevention, Atlanta, GA,
United States, 8iGate Clinical Research International, Mumbai, India, 9Serum
Institute of India Ltd, Pune, India
Filariasis II - Chemotherapy and Resistance
Liberty C
10:15 a.m. - Noon
CHAIR
Mike Osei-Atweneboana
11:15 a.m.
382
McGill University, St. Anne-De-Bellevue, QC, Canada
THE PREVALENCE OF RHEUMATIC HEART DISEASE AMONG
CHILDREN IN BAMAKO, MALI
1
Wilma Stolk
Erasmus Medical Center, Rotterdam, The Netherlands
2
Melissa B. Rosenberg , Mahamadou M. Keita , Kassoum M.
Sanogo3, Milagritos D. Tapia1, James Dale4, Samba O. Sow2,
Karen Kotloff1
10:15 a.m.
385
1
University of Maryland Center for Vaccine Development, Baltimore, MD,
United States, 2Centre pour le Développement des Vaccins – Mali, Bamako,
Mali, 3Hôpital Gabriel Touré, Bamako, Mali, 4University of Tennessee,
Memphis, TN, United States
11:30 a.m.
MODELLING THE SPREAD OF ANTHELMINTIC RESISTANCE
Thomas S. Churcher, María-Gloria Basáñez
10:30 a.m.
383
VIRAL HEPATITIS IN NEWLY ARRIVED IMMIGRANTS AND
REFUGEES
Christina Greenaway1, Pierre Dongier2, Jean-Francois Boivin3,
Bruce Tapiero4, Mark Miller1, Kevin Schwartzman3
1
Division of Infectious Diseases, SMBD Jewish General Hospital, Montreal,
QC, Canada, 2CLSC Côte-des-Neiges, Montreal, QC, Canada, 3Department
of Epidemiology, McGill University, Montreal, QC, Canada, 4Division of
Infectious Diseases, Ste. Justine Hospital, Montreal, QC, Canada
386
PHENOTYPIC EVIDENCE OF EMERGING IVERMECTIN RESISTANCE IN SOME POPULATION OF ONCHOCERCA VOLVULUS,
THE CAUSATIVE AGENT OF ONCHOCERCASIS
Mike Y. Osei-Atweneboana1, Jeffrey L. Eng1, Daniel A. Boakye2,
John O. Gyapong3, Roger K. Prichard1
1
McGill University, Ste. Anne-De-Bellevue, QC, Canada, 2Noguchi Memorial
Institute for Medical Research, University of Ghana, Ghana, 3Ghana Health
Services, Health Research Unit, Ghana
111
Tuesday, November 6
TREATMENT OF AMERICAN CUTANEOUS LEISHMANIASIS PREVIOUS TO ULCER DEVELOPMENT IS ASSOCIATED WITH HIGH
RATE OF FAILURE IN NORTHWEST BRAZIL
Detailed Program
www.astmh.org
10:45 a.m.
Symposium 77
387
THE ALTERED STATE OF ONCHOCERCAL NODULES AFTER
TREATMENT WITH IVERMECTIN; INSIGHTS INTO MECHANISMS
OF CHEMOTHERAPEUTIC ACTION
Charles D. Mackenzie1, Guillermo Zea-Flores2, Juan-Carlos Viera3,
Roberto Proano3, Rob R. Eversole4
1
Michigan State University, East Lansing, MI, United States, 2OEPA,
Guatemala City, Guatemala, 3Onchocerciasis Control Program, Quito,
Ecuador, 4Western Michigan University, Kalamazoo, MI, United States
Anopheles Anti-Plasmodium Defense Systems
Franklin 3/4
The past decade has experienced a dramatic proliferation of our knowledge
on the molecular biology of the malaria vector Anopheles gambiae. This
symposium will address the latest breakthroughs and discoveries on genes
and mechanisms that are implicated in defending the Anopheles mosquito
against Plasmodium infection.
CHAIR
11 a.m.
388
TARGETING ENDOSYMBIOTIC WOLBACHIA IN WUCHERERIA
BANCROFTI REDUCES PLASMA VEGF-A AND IMPROVES CONDITION OF HYDROCELE PATIENTS
Alexander Yaw Debrah1, Sabine Mand1, Mohamad Reza Toliat4,
Yeboah Marfo-Debrekyei2, Linda Batsa2, Peter Nuernberg4,
Bernard Lawson3, Ohene Adjei5, Achim Hoerauf1, Kenneth Pfarr1
1
Institute for Medical Microbiology, Immunology and Parasitology, University
of Bonn, Bonn, Germany, 2Kumasi Centre for Collaborative Research in
Tropical Medicine (KCCR), Kumasi, Ghana, 3Department of Theoretical and
Applied Biology, Kwame Nkrumah University of Science and Technology,
Kumasi, Ghana, 4Cologne Centre for Genomics (CCG), University of
Cologne, Germany, 5School of Medical Sciences, Kwame Nkrumah
University of Science and Technology, Kumasi, Ghana
George Dimopoulos
10:15 a.m.
THE ROADS TO NOWHERE: THE REGULATION OF NITRIC
OXIDE-MEDIATED MALARIA PARASITE KILLING
Shirley Luckhart
University of California at Davis, Davis, CA, United States
10:45 a.m.
PLASMODIUM SPOROZOITE DESTRUCTION IN THE
ANOPHELES HAEMOCOEL
Julian Hillyer
Vanderbilt University, Nashville, TN, United States
11:15 a.m.
389
WOLBACHIA ENDOBACTERIA DEPLETION BY DOXYCYCLINE
AS ANTIFILARIAL THERAPY IS MACROFILARIDICAL IN
ONCHOCERCIASIS
Achim Hoerauf1, Sabine Specht1, Marcelle Büttner2,
Kenneth Pfarr1, Sabine Mand1, Rolf Fimmers1, Yeboah MarfoDebrekyei3, Peter Konadu4, Alexander Y. Debrah1,
Claudio Bandi5, Norbert Brattig2, Anna Albers1, Linda Batsa3,
Ohene Adjei4, Dietrich W. Büttner2
1
University Clinic Bonn, Bonn, Germany, 2Bernhard Nocht Institute for
Tropical Medicine, Hamburg, Germany, 3Kumasi Centre of Collaborative
Research, Kumasi, Ghana, 4Kwame Nkrumah University of Science and
Technology, Kumasi, Ghana, 5University of Milan, Milan, Italy
11:10 a.m.
ANOPHELES SERPINS IN THE DEFENCE AGAINST
PLASMODIUM
Kristin Michel
Kansas State University, Manhattan, KS, United States
11:35 a.m.
INTERACTIONS BETWEEN ANOPHELES ANTI-BACTERIAL AND
ANTI-PLASMODIUM DEFENSE SYSTEMS
George Dimopoulos
11:30 a.m.
390
EOSINOPHILS ARE NOT REQUIRED FOR DEC-MEDIATED
CLEARANCE OF MICROFILAREMIA
Amy D. Klion, Kawsar Talaat, Sandy White, Helene Rosenberg,
Thomas B. Nutman
11:45 a.m.
112
Exhibit Hall Open
www.astmh.org
395
Tuesday, November 6, 2007 Noon - 3 p.m.
Poster Session B/Light Lunch (#391 – 620)
Franklin Hall B
Noon - 1:30 PM
Arthropods/Entomology - Other
HUMAN IMMUNE RESPONSES AGAINST PHLEBOTOMUS PAPATASI SALIVA
Rami M. Mukbel1, Glenn Wortmann2, Emil Lesho2, Vinita Tripathi1,
Mariha Wadsworth1, Gwen Stayback1, Fabiano Oliveira3,
Shaden Kamhawi3, Jesus Valenzuela3, Marcelo Ramalho-Ortigao1,
Mary Ann McDowell1
1
University of Notre Dame, Notre Dame, IN, United States, 2Walter Reed
Army Medical Center, Washington DC, United States, 3National Institutes of
(ACMCIP Abstract)
391
LUTZOMYIA LONGIPALPIS SALIVARY RECOMBINANT PROTEINS RECOGNIZED BY HUMAN, DOG AND FOX ANTIBODIES
Regis B. Gomes1, Nicolas Collin1, Clarissa Teixeira1, Ryan Jochim1,
Dia-eldin Elnaiem1, Peter Volf2, Carlos Costa3, Jesus G. Valenzuela1
1
Health, Rockville, MD, United States, 2Charles University, Prague, Czech
Republic, 3Universidade Federal do Piauí, Teresina, Brazil
392
DETERMINANTS OF TRIATOMA INFESTANS INFESTATION
CLUSTERING IN RURAL COMMUNITIES OF MORENO DEPARTMENT, NORTHWESTERN ARGENTINA
396
MOLECULAR BASIS OF SPECIFICITY AND CROSS REACTIVITY
IN DELAYED-TYPE-HYPERSENSITIVITY REACTIONS TO BITES OF
SAND FLIES AND IMPLICATION FOR PROTECTION AGAINST
LEISHMANIA INFECTION
Dia-Eldin A. Elnaiem, Luiz F. Oliveira, Regis B. Gomes, Clarissa
Toxeira, Sreenath Subrahmanyam, Shaden Kamhawi, Phillip G.
Lawyer, Jerrold M. Ward, Jesus G. Valenzuela
National Insititue of Allergy and Infectious Diseases, National Institutes of
(ACMCIP Abstract)
397
Gonzalo M. Vazquez Prokopec1, Cynthia Spillmann2,
Mario Zaidenberg2, Uriel Kitron3, Ricardo E. Gürtler1
PHLEBOTOMUS PAPATASI SALIVARY GLAND SEQUENCE VARIABILITY AND IMPACT ON DEFINING VACCINE CANDIDATES
1
Marcelo Ramalho-Ortigao1, Valdir Q. Balbino1, Iliano V. CoutinhoAbreu1, Rami Mukbel1, Emad Fawaz2, Shaaban El-Hossary2, Hanafi
Hanafi2, David Hoel2, Mahmoud Abo-Shehada3, Jesus Valenzuela4,
Shaden Kamhawi4, Mary Ann McDowell1
Laboratorio de Eco-Epidemiología, Universidad de Buenos Aires, Buenos
Aires, Argentina, 2Coordinación Nacional de Control de Vectores, Ministerio
de Salud y Ambiente de la Nación, Córdoba, Argentina, 3Department of
Pathobiology, University of Illinois, Urbana, IL, United States
393
IMMUNOMODULATORY EFFECTS OF SALIVARY GLAND
EXTRACT OF BLACK FLY, SIMULIUM VITTATUM (DIPTERA:
SIMULIIDAE) ON MOUSE SPLENOCYTES
Hitoshi Tsujimoto, Donald E. Champagne
(ACMCIP Abstract)
394
HIDDEN SYLVATIC FOCI OF TRIATOMA INFESTANS IN THE
ARGENTINE CHACO: A THREAT TO THE VECTOR ELIMINATION
CAMPAIGN?
Leonardo A. Ceballos1, Uriel Kitron2, Romina V. Piccinali1, Paula L.
Marcet1, Marta V. Cardinal1, Judith Schachter-Broide1, Jean-Pierre
Dujardin3, Ellen Dotson4, Ricardo E. Gürtler1
1
Laboratorio de Eco-Epidemiología, Departamento de Ecología, Genética y
Evolución, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos
Aires, Buenos Aires, Argentina, 2College of Veterinary Medicine, University
of Illinois at Urbana-Champaign, Urbana, IL, United States, 3Unité Mixte de
Recherche, Institut de Recherches pour le Développment-Centre National de
Recherche Scientifique, Montpellier, France, 4Centers for Disease Control
and Prevention, Division of Parasitic Diseases, Entomology Branch,
Chamblee, GA, United States
1
University of Notre Dame, Notre Dame, IN, United States, 2Naval Medical
Research Unit #3, Cairo, Egypt, 3Jordan University of Science and
Technology, Irbid, Jordan, 4National Institutes of Health, Rockville, MD,
United States
398
TEMPORAL AND SPATIAL VARIATION IN ABUNDANCE OF THE
MALARIA VECTOR ANOPHELES (ANOPHELES) PSEUDOPUNCTIPENNIS IN NORTHERN ARGENTINA
María J. Dantur Juri1, Mario Zaidenberg2, Guillermo L. Claps1,
Mirta Santana3, Walter R. Almirón4
1
Institute of Entomology “Dr. Abraham Willink”, School of Natural Sciences
and Miguel Lillo Institute, The National University of Tucumán, San Miguel
de Tucumán, Tucumán, Argentina, 2National Coordination of Vector Control,
Health Ministry of Argentina, Salta, Argentina, 3Biostatistics Department,
School of Medicine, National University of Tucumán, San Miguel de
Tucumán, Tucumán, Argentina, 4Centre of Entomologic Research of
Córdoba, School of Physical, Exact and Natural Sciences, National University
of Córdoba, Córdoba, Argentina
113
Tuesday, November 6
Franklin Hall B
Detailed Program
www.astmh.org
399
403
AN UNUSUAL CASE OF ALIMENTARY CANAL INFESTATION BY
THE MILLIPEDE BRACHYIULUS LUSITANUS (DIPLOPODA) IN A
5 YEAR OLD BOY. A CASE REPORT
COMPARISON OF ECOSYSTEMIC AND TRADITIONAL METHODS FOR THE LONG TERM CONTROL OF THE CHAGAS’ VECTOR TRIATOMA DIMIDIATA IN JUTIAPA, GUATEMALA
G. R. Mowlavi1, S. R. Naddaf2, M. Rezaeian1, I. Mobedi1, N. Najafi3,
D. D. Bowman4, A. Lucio-Forster4, R. L. Hoffman5
Dulce M. Bustamante1, Carlota Monroy2, Sandy Pineda2,
Antonieta Rodas2, Xochitl Castro2, Virgilio Ayala3, Javier Quinonez3,
Barbara Moguel2, Ranferi Trampe4, Leonicio Revolorio4
1
School of Public Health and Institute of Public Health Research of Tehran
University of Medical Sciences, Tehran, Islamic Republic of Iran, 2Pasteur
Institute of Iran, Tehran, Islamic Republic of Iran, 3Mazandaran University of
Medical Sciences, Sari, Islamic Republic of Iran, 4Cornell University, Ithaca,
NY, United States, 5Virginia Museum of Natural History, Martinsville, VA,
United States
University of Florida, Vero Beach, FL, United States, 2LENAP, Universidad de
San Carlos de Guatemala, Ciudad de Guatemala, Guatemala, 3Facultad de
Ingenieria, Universidad de San Carlos de Guatemala, Ciudad de Guatemala,
Guatemala, 4Ministerio de Salud Pubica y Asistencia Social, Jutiapa,
Guatemala
400
SELECTIVE DELTAMETHRIN SPRAYING OF TRIATOMINE INFESTED HOUSES FOR THE CONTROL OF CHAGAS DISEASE IN
SOUTHERN ECUADOR
1
2
2
Mario J. Grijalva , Anita G. Villacis , Esteban G. Baus , Cesar A.
Yumiseva2, Sofia Ocaña-Mayorga2, Paula Castellanos-Cuervo2,
Mauricio S. Lascano1, Santiago Davila3, Jorge Monroy-Nicola4, Laura
Arcos-Teran2, Christopher J. Schofield5
1
Tropical Disease Institute, Biomedical Sciences Department, College of
Osteopathic Medicine, Ohio University, Athens, OH, United States, 2Center
for Infectious Disease Research, School of Biological Sciences, Pontifical
Catholic University, Quito, Ecuador, 3PLAN Internacional, Quito, Ecuador,
4
Chagas Disease Control Program, Ministry of Public Health, Guayaquil,
Ecuador, 5ECLAT, London School of Hygiene and Tropical Medicine, London,
United Kingdom
1
404
FEASIBILITY, ACCEPTABILITY AND SAFETY OF ARTEMETHERLUMEFANTRINE IN HOME MANAGEMENT OF
UNCOMPLICATED MALARIA IN SOUTHWEST NIGERIA
Ikeoluwapo O. Ajayi1, Bidemi Yusuf1, Catherine O. Falade1, Sola
Gbotosho1, Benjamin Olley2, Christian Happi1, Yemisi Iyiola3
1
College of Medicine, Ibadan, Nigeria, 2Social Sciences Department,
University of Ibadan, Ibadan, Nigeria, 3Ministry of Health, Ibadan, Nigeria
405
FEVER AND THE RECENT INTERNATIONAL TRAVELER
PRESENTING TO THE EMERGENCY DEPARTMENT
John Cahill1, Ryan David2
401
EVALUATION OF NOVEL LONG-LASTING, INSECTICIDEIMPREGNATED BED NETS TO CONTROL ADULT SAND FLIES
(DIPTERA: PHLEBOTOMINAE) IN HUMAN LANDING STUDIES IN
KENYA AND EGYPT
Gabriela Zollner1, David Hoel2, Hanafi A. Hanafi2, Jason H.
Richardson3, Richard Mukabana3, Russell E. Coleman1
1
2
U.S. Naval Medical Research Unit No. 3, Cairo, Egypt, 3US Army Medical
Research Unit, Nairobi, Kenya
1
St. Lukes/Roosevelt Hospital, New York, NY, United States, 2Jacobi Medical
Center, New York, NY, United States
406
ASSESSMENT OF A TREATMENT GUIDELINE TO IMPROVE
HOME MANAGEMENT OF MALARIA
Ikeoluwapo O. Ajayi, Oladele Kale, Afolabi E. Bamgboye,
Oladimeji Oladepo
College of Medicine, Ibadan, Nigeria
407
402
FAST-ID: FLIGHT SIGNATURE RECORDINGS OF AEDES AND
CULEX MOSQUITOES FOR AUTOMATED SPECIES IDENTIFICATION AND VECTOR SURVEILLANCE
1
1
2
Philipp Kirsch , John McLaughlin , Charles Apperson , Aubrey
Moore3, Darek Czokajlo1, Luma Abu Ayyash2
APTIV Inc., Portland, OR, United States, 2North Carolina State University,
Raleigh, NC, United States, 3University of Guam, Mangilao, GU, United
States
USING “MOTHER TRAINERS” FOR MALARIA CONTROL: THE
NIGERIAN EXPERIENCE
Ikeoluwapo O. Ajayi, Oladele Kale, Afolabi E. Bamgboye
College of Medicine, Ibadan, Nigeria
408
1
COMMON INFECTIOUS AND NON-INFECTIOUS DISEASES
AMONG RECENT IMMIGRANTS AT THE SOUTH BRONX’S
REFUGEE AND IMMIGRANT CLINIC
Ramin G. Asgary, Sara Doorley
Albert Einstein College of Medicine, New York, NY, United States
114
409
Ousmane Faye1, Seydou Doumbia2, Adama Dicko3, Karim
Coulibaly3, Pierre Traore3, Hawa Sagara3, Kouressi Tall3,
Somita Keita3
1
National Center for Diseases Controle, Bamako, Mali, 2Malaria Research
and Training Center, Bamako, Mali, 3Marchoux Institute, National Center for
Diseases Controle, Bamako, Mali
410
CLINICAL PROFILE OF DENGUE OUTBREAK IN A DEVELOPING
NATION (2003-2005)
Vineet Gupta, Sanjeev Bhoi
415
DOXYCYLINE NONCOMPLIANCE RESULTS IN SEVERE AND
COMPLICATED FALCIPARUM MALARIA IMPORTED FROM
CHAD
Lucia Gerena1, Michael Shusko2, David Krulak3, Mike Favata4,
Donald A. Neil5, Jean-Paul Chretien6, Victor MacIntosh6, David L.
Saunders1, Alan J. Magill1, Peter J. Weina1, Wilbur K. Milhous1
1
Group Surgeon Marine Special Operations Advisor Group, Camp Lejeune,
NC, United States, 3Group Surgeon, Marine Special Operations Support
Group, Camp Lejeune, NC, United States, 4Naval Hospital, Camp Lejeune,
NC, United States, 5Disease Intervention and Prevention Specialist
Department Head Preventive, Camp Lejeune, NC, United States, 6DoD
Global Emerging Infections Surveillance and Response System (DoD-GEIS),
Silver Spring, MD, United States
2
All India Institute of Medical Sciences, New Delhi, India
411
CASE REPORT OF A TRAVELER WITH LEISHMANIA PANAMENSIS TREATED WITH MILTEFOSINE
Jeffrey G. Jones
St. Francis Traveler’s Health Center, Indianapolis, IN, United States
416
CLINICAL, LABORATORY, AND MOLECULAR DETERMINANTS
OF EPIDEMIC SEVERE AND COMPLICATED MALARIA (SCM) IN
THE PERUVIAN AMAZON
R. Witzig1, A. H. Quino2, M. Rios1, M. Santolalla3, M. A. Dery2, C.
Salas3, D. J. Bacon3
1
412
REPORT OF THE UNITED STATES - EUROPEAN COMMISSION
WORKSHOP “ADVANCES IN IMMUNOLOGY AND VACCINE
DISCOVERY”
Thomas L. Richie1, Cyril G. Gay2
1
Agricultural Reseach Service, U.S. Department of Agriculture, Beltsville, MD,
United States
2
413
THE RELATIONSHIP BETWEEN MALARIA MORBIDITY AND
AVAILABILITY OF HEALTHCARE FACILITY IN PARTS OF THE
IMO RIVER BASIN, SOUTHEASTERN NIGERIA
Ikechukwu N. Dozie1, Uchechukwu M. Chukwuocha2, Betram E.
Nwoke1, Celestine O. Onwuliri2
1
Imo State University, Owerri, Imo State, Nigeria, 2Federal University of
Technology, Owerri, Imo State, Nigeria
414
RISING TREND OF CARDIOVASCULAR DISEASES AMONG
SOUTH WESTERN NIGERIAN FEMALE PATIENTS
Tulane University Medical School, New Orleans, LA, United States,
Hospital Apoyo, Iquitos, Peru, 3Naval Medical Research Center Detachment,
Lima, Peru
2
417
CORRECTION OF CENTRAL NERVOUS SYSTEM METABOLIC
ABNORMALITIES, DEFICITS IN EXECUTIVE COGNITIVE FUNCTIONING AND ELEVATED C4A: A CLINICAL TRIAL USING LOW
DOSE ERYTHROPOIETIN IN PATIENTS SICKENED BY EXPOSURE
TO WATER-DAMAGED BUILDINGS (WDB)
Ritchie C. Shoemaker
Center for Research on Biotoxin Associated Illnesses, Pocomoke, MD, United
States
(ACMCIP Abstract)
418
DEFINING MOLD ILLNESS IN CHILDREN: A CHRONIC INFLAMMATORY ILLNESS WITH DISTINCTIVE BIOMARKERS
States
(ACMCIP Abstract)
419
Aduragbenro D. Adedapo
College of Medicine, University of Ibadan, Nigeria, Ibadan, Nigeria
SEQUENTIAL UPREGULATION OF INNATE IMMUNE RESPONSES
DURING ACUTE ACQUISITION OF ILLNESS IN PATIENTS
EXPOSED PROSPECTIVELY TO WATER-DAMAGED BUILDINGS
(WDB)
States
(ACMCIP Abstract)
115
Tuesday, November 6
THERMOTHERAPY VERSUS MEGLUMINE ANTIMONIATE IN
THE TREATMENT OF CUTANEAOUS LEISHMANIASIS IN MALI
www.astmh.org
Detailed Program
www.astmh.org
420
CLINICAL AND EPIDEMIOLOGICAL STUDIES OF ANTERIOR SEGMENT DISORDERS DUE TO ONCHOCERCIASIS IN IMO STATE,
NIGERIA
Yaoundé, Cameroon, 2The Biotechnology Centre, University of Yaoundé I,
Yaoundé, Cameroon, 3Department of Biology, Georgetown University,
Washington, DC, 4AZ Data Clinic, Inc., Rockville, MD, United States,
5
Department of Pediatrics, Georgetown University, Washington, DC,
United States
426
Ugonna F. Nwigwe1, Francis O. Iwuagwu1, Ikechukwu N. Dozie1,
Uchechukwu M. Chukwuocha2
1
Imo State University, Owerri, Nigeria, 2Federal University of Technology,
Owerri, Nigeria
421
IMPACT OF REPEATED ADMINISTRATION OF ACTS ON SAFETY,
EFFICACY AND INCIDENCE OF UNCOMPLICATED MALARIA IN
MALI
Abdoulaye Djimde1, Bakary Fofana1, Issaka Sagara1, Bakary
Sidibe1, Sekou Toure1, Demba Dembele1, Amadou Togo1, Kassim
Sanogo1, Souleymane Dama1, Alassane Dicko1, Valerie Lameyre2,
Christopher V. Plowe3, Ogobara K. Doumbo1
1
University of Bamako, Bamako, Mali, 2Sanofi-Aventis, Paris, France,
3
422
COST ANALYSIS FOR SCHISTOSOMIASIS CONTROL IN
PLATEAU AND NASARAWA STATES, NIGERIA
Julie R. Gutman1, Abel Eigege2, John Umaru2, Kal Alphonsus2,
Emmanuel S. Miri2, Frank O. Richards3
1
Emory University, Atlanta, GA, United States, 2The Carter Center, Jos,
Nigeria, 3The Carter Center, Atlanta, GA, United States
423
RANDOMIZED COMPARISON OF AMODIAQUINE-SULFADOXINE/PYRIMETHAMINE, ARTEMETHER-LUMEFANTRINE, AND
DIHYDROARTEMISININ-PIPERAQUINE FOR THE TREATMENT
OF UNCOMPLICATED FALCIPARUM MALARIA IN BURKINA
FASO
Issaka Zongo1, Dorsey Grant2, Noel Rouamba1, Christian
Dokomajilar2, Yves Sere1, Philip J. Rosenthal2, Jean Bosco
Ouedraogo1
1
Institut de Recherche en Sciences de la Sante, Direction Regionale de
l’Ouest, Bobo-Dioualasso, Burkina Faso, 2University of California, San
MICROSPORIDIOSIS AND MALNUTRITION IN UGANDAN CHILDREN WITH PERSISTENT DIARRHEA
Siobhan M. Mor1, James K. Tumwine2, Grace Ndeezi2,
Saul Tzipori1
1
Division of Infectious Diseases, Tufts Cummings School of Veterinary
Medicine, North Grafton, MA, United States, 2Department of Pediatrics
and Child Health, Mulago Hospital, Makerere University Medical School,
Kampala, Uganda
427
AN IMPORTED CASE OF PEDIATRIC MELIOIDOSIS: SOMETIMES
HOOFBEATS ARE ZEBRAS!
Tobey A. Audcent, Anne E. McCarthy
University of Ottawa, Ottawa, ON, Canada
428
EOSINOPHILIA AS A DIAGNOSTIC TOOL FOR
ANGIOSTRONGYLIASIS
Kittisak Sawanyawisuth1, Somsak Tiamkao2, Pewpan M.
Intapan2, Panita Limpawattana2, Wichai Senthong2, Suthipun
Jitpimolmard2, Verajit Chotmongkol2, Elizabeth B. Connor1
1
University of California, San Diego, La Jolla, CA, United States, 2Khon Kaen
University, Khon Kaen, Thailand
429
LEPTOSPIROSIS IN NEPAL
Khin S. Myint1, Clinton K. Murray2, Robert McNair Scott3,
Mrigendra P. Shrestha3, Mammen P. Mammen1, Gyan B. Thapa4,
Sanjaya K. Shrestha3, Robert A. Kuschner5, Durga M. Joshi4, Robert
V. Gibbons1
1
Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand,
Brooke Army Medical Center, Sam Houston, TX, United States, 3Walter
Reed/Armed Forces Research Institute of the Medical Sciences Research Unit
Nepal, Kathmandu, Nepal, 4Nepalese Army, Kathmandu, Nepal, 5Walter
2
424
430
EFFICACY AND SAFETY OF AMODIAQUINE-ARTESUNATE AND
ARTEMETHER-LUMEFANTRINE FOR THE TREATMENT OF
UNCOMPLICATED FALCIPARUM MALARIA IN BURKINA FASO
DEVELOPMENT OF A LEPTOSPIROSIS REAL TIME PCR BASED
ON LIPL32
Issaka Zongo, Noel Rouamba, Jean Bosco Ouedraogo
Kurt E. Schaecher, Duangkamon Siludjai, Mark Fukuda
Institut de Recherche en Sciences de la Sante, Direction Regionale de
l’Ouest, Bobo-Dioualasso, Burkina Faso
Armed Forces Research Institute of Research, Bangkok, Thailand
425
ANTIMALARIAL IGG AND IGG SUBCLASS RESPONSES IN
CAMEROONIAN CHILDREN WITH SEVERE AND UNCOMPLICATED MALARIA
Viviane Helene Matong Tchinda1, Genevieve Giny Fouda3, Diane
Wallace Taylor3, Ainong Zhou4, Armead Johnson5, Ababacar Diouf3,
Simon Metenou3, and Rose Gana Fomban Leke2
431
INVESTIGATION OF POSSIBLE ROLE OF TOXOPLASMOSIS IN
PATIENTS WITH FIRST EPISODE SCHIZOPHRENIA
Mehmet Tanyuksel1, Ozcan Uzun1, Engin Araz1, Ozgur Koru1,
Cahit Babur2
1
GMMA, Ankara, Turkey, 2Refik Saydam Hifzisihha Center, Ankara, Turkey
1
The Medical Research Centre, Institute of Medical Research and Medicinal
Plant Studies (IMPM), Ministry of Scientific Research and Innovation,
116
432
www.astmh.org
438
DIAGNOSIS OF ACUTE FEBRILE ENCEPHALOPATHY IN ADULTS:
WHAT REALLY HELPS THE CLINICIAN?
SEROPREVALENCE TO RICKETTSIOSES IN U.S. MILITARY
FORCES DEPLOYED TO KOREA
Ashish Bhalla, John Manchery, Vikas Suri, Sushil Mahi, Navneet
Sharma, Subhash Varma, Paramjit Singh, N. Khandelwal
Paul C. Graf1, Allen L. Richards1, Karla R. Manuel1, Jenny Lay2,
Remington Nevin2, Joel C. Gaydos3, Jean-Paul Chretien3
Post Graduate Institute of Medical Education and Research,
Chandigarh, India
1
433
Enteric Vaccines
DEVELOPMENT OF MOLECULAR AND ENZYMATIC ASSAYS TO
SURVEY FOR PERMETHRIN RESISTANCE IN SCABIES MITES
439
Cielo J. Pasay1, Shelley Walton2, Deborah Holt2, Larry Arlian3,
Marjorie Moran3, Robin Gunning4, Louise Rossiter5, Simone
Beckham1, Angelika Rose1, James McCarthy1
1
Queensland Institute of Medical Research, Brisbane, Queensland, Australia,
Menzies School of Health Research, Darwin, Northern Territory, Australia,
3
Wright State University, Dayton, OH, United States, 4NSW Department of
Primary Industries, Tamworth, NSW, Australia, 5NSW Department of Primary
Industries, Narrabri, NSW, Australia
2
434
PROTECTIVE EFFICACY OF THE 56 KDA ANTIGEN FROM KARP
AND KATO STRAINS OF O. TSUTSUGAMUSHI IN HOMOLOGUS
AND HETEROLOGOUS CHALLENGED MOUSE MODEL
ASSESSING THE POTENTIAL IMPACT OF VACCINATION ON
PREVENTION OF ROTAVIRUS DEATHS AMONG CHILDREN IN
RURAL GHANA
Melissa Arvay1, Sophia Terp2, George Armah3, Peter Wontuo4,
Aaron Curns1, Marc-Alain Widdowson1, Umesh Parashar1, Roger I.
Glass5, Fred Binka6
1
Centers for Disease Control and Prevention Foundation, Atlanta, GA,
United States, 3Noguchi Memorial Institute for Medical Research, University
of Ghana, Legon, Ghana, 4Navrongo Health Research Center, Navrongo,
Ghana, 5Fogarty International Center, U.S. National Institutes of Health,
Bethesda, MD, United States, 6School of Public Health, University of Ghana,
Legon, Ghana
2
Chien-Chung Chao1, Elissa A. Mutumanje2, Teik-Chye Chan2,
Suchismita Chattopadhyay2, Allen L. Richards2, Wei-Mei Ching2
1
VRDD/IDD/Naval Medical Research Center, Silver Spring, MD, United States,
VRDD/IDD/Naval Medical Research Center and Uniformed Services
University of the Health Sciences, Bethesda, MD, United States
2
435
TEN YEARS OF TICKS SUBMITTED TO THE HUMAN TICK TEST
KIT PROGRAM OF THE U.S. ARMY CENTER FOR HEALTH
PROMOTION AND PREVENTIVE MEDICINE
440
NEW CLY-A VACCINES SHOW POTENTIAL PROTECTION
AGAINST CRYPTOSPORIDIUM INFECTION
Andrea N. Davis-Rivers1, Fernando Tenjo2, Richard L. Guerrant1,
Gregory A. Buck2
1
University of Virginia, Charlottesville, VA, United States, 2Virginia
Commonwealth University, Richmond, VA, United States
(ACMCIP Abstract)
Ellen Y. Stromdahl, Mary Vince, Sandra Evans
U.S. Army Center for Health Promotion and Preventive Medicine, Aberdeen
Proving Ground, MD, United States
436
SERO-DIAGNOSIS OF MURINE TYPHUS USING RECOMBINANT
OMPB FRAGMENTS IN ELISA
Hua-Wei Chen, Chien-Chung Chao, Elissa Mutumanje,
Wei-Mei Ching
441
DEVELOPING RNAI-BASED RESISTANCE TO MULTIPLE DENGUE
VIRUS SEROTYPES IN MOSQUITOES (AEDES AEGYPTI)
Valérie Barbosa-Solomieu, Irma Sanchez-Vargas, Alexander Franz,
Ken E. Olson
442
Naval Medical Research Center, Silver Spring, MD, United States
437
INTERSPECIFIC HYBRIDIZATION YIELDS NOVEL FILARIASIS
VECTOR ELIMINATION APPROACH
TM
PLATELIA DENGUE NS1 ANTIGEN ASSAY: INNOVATIVE
ASSAY FOR EARLY DIAGNOSIS OF ACUTE DENGUE INFECTION
Marc Tabouret1, Christophe Salanon2, Patrice Sarfati2
1
Bio-Rad, Steenvoorde, France, 2Bio-Rad, Marnes La Coquette, France
Corey L. Brelsfoard, Stephen L. Dobson
University of Kentucky, Lexington, KY, United States
117
Tuesday, November 6
Ectoparasite-Borne Disease
Army Medical Surveillance Activity, Washington, DC, United States,
3
Department of Defense, Global Emerging Infections System, Silver
2
Detailed Program
www.astmh.org
443
450
ROLE OF A NS1 AG ELISA IN THE VIROLOGICAL DIAGNOSIS
OF DENGUE INFECTION AND ITS VALUE FOR DENGUE VACCINE TRIALS
INHIBITION OF VIRAL REPLICATION IN HUMAN LIVER CELLS
BY SHORT INTERFERING RNA DIRECTED TO 5’-NONCODING
REGION OF DENGUE-2 VIRUS
Denis Crevat1, Marc Tabouret2, Vu Thi Que Huong3, Veronique
Barban4, Patrice Sarfati2, Christine Luxemburger4, Nguyen Thi Kim
Tien3, Jean Lang4
Alessandra C. Gomes-Ruiz1, Breno M. Silva2, Cláudio A. Bonjardim2,
Benedito A. Fonseca1
1
Sanofi Pasteur, Swiftwater, PA, United States, 2Bio-Rad Laboratories,
Marnes-la-Coquette, France, 3Institut Pasteur, Ho Chi Minh City, Vietnam,
4
Sanofi Pasteur, Marcy l’Etoile, France
444
EVALUATION OF A DUAL-USE, FIELD-DEPLOYABLE,
DRY-FORMAT, QUANTITATIVE REVERSE TRANSCRIPTIONPOLYMERASE CHAIN REACTION (QRT-PCR) ASSAY
FOR DETECTION OF DENGUE VIRUS IN MOSQUITOES
AND HUMANS
Subhamoy Pal1, James McAvin2, Sajeewane Ekanayake1, Russell
Coleman3, James Swaby2, Tadeusz Kochel4, Curtis Hayes1, Kevin
Porter1, Shuenn-Jue Wu1
Naval Medical Research Center, Silver Spring, MD, United States, 2Clinical
Research Division, 59 CRES/MSR, Lackland Air Force Base, TX, United States,
3
Division of Entomology, Walter Reed Army Institute of Research, Silver
Spring, MD, United States, 4Naval Medical Research Center Detachment,
Lima, Peru
1
School of Medicine of Ribeirão Preto, Ribeirão Preto, S.P., Brazil, 2Federal
University of Minas Gerais, Belo Horizonte, MG, Brazil
451
PROSPECTIVE STUDY OF DENGUE INFECTION IN SCHOOL
CHILDREN IN LONG XUYEN, VIETNAM
Thi Kim Tien Nguyen1, Christine Luxemburger2, Trong Toan
Nguyen1, Thi Que Huong Vu1, Ngoc Rang Nguyen3, Laurence
Pollissard2, Jean Lang4
1
Pasteur Institute, Ho Chi Minh City, Vietnam, 2sanofi pasteur,
Epidemiology Department, Lyon, France, 3An Giang Hospital, Long Xuyen,
Vietnam, 4sanofi pasteur, Research and Development Department, Marcy
l’Etoile, France
452
1
445
IMMUNOHISTOCHEMISTRY ON SKIN BIOPSIES FROM
VIETNAMESE PATIENTS WITH DENGUE SHOCK SYNDROME
Bridget Wills1, Tran V. Diet2, Dinh T. Trung3, Robert Goldin4,
Alpana Lad4, Nguyen M. Dung2, Michael Levin4, Jeremy Farrar1
1
Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam,
Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam, 3University of
Medicine and Pharmacy, Ho Chi Minh City, Vietnam, 4Imperial College,
2
INTERFERON-ALPHA IMMUNE MODULATION IN A DENDRITIC
CELL - T LYMPHOCYTE MODEL OF SEVERE DENGUE DISEASE
Patrick W. Hickey, Dupeh R. Palmer, Julia A. Lynch
453
446
MOLECULAR CHARACTERIZATION OF DENGUE
VIRUSES ISOLATED IN MEDELLIN, COLOMBIA
AND SURROUNDING AREAS
Francisco J. Diaz1, Marta C. Ospina2, Edwin A. Higuita1,
Jorge E. Osorio3
1
Universidad de Antioquia, Medellin, Colombia, 2Laboratorio de Salud
Publica de Antioquia, Medellin, Colombia, 3University of Wisconsin,
Madison, WI, United States
447
FACTORS INFLUENCING THE TEMPORAL PATTERN OF CLASSIC
DENGUE FEVER IN SINGAPORE
Joseph R. Egger
ANALYSIS OF AGREEMENT BETWEEN INDIVIDUAL AND
COMBINED CLINICAL AND LABORATORY FINDINGS AND
AN EXPERT PHYSICIAN’S DIAGNOSIS OF DENGUE
HEMORRHAGIC FEVER
James A. Potts1, Siripen Kalayanarooj2, Suchitra Nimmannitya2,
Anon Srikiatkhachorn3, Ananda Nisalak4, David W. Vaughn5,
Wenjun Li6, Sharone Green3, Alan L. Rothman3
1
Clinical and Population Health Research Division, University of
Massachusetts Medical School, Worcester, MA, United States, 2Queen Sirikit
National Institute of Child Health, Bangkok, Thailand, 3Center for Infectious
Disease and Vaccine Research, University of Massachusetts Medical School,
Worcester, MA, United States, 4Armed Forces Research Institute of Medical
Sciences, Bangkok, Thailand, 5U.S. Army Medical Research and Materiel
Command, Fort Detrick, MD, United States, 6Preventive and Behavioral
Medicine, University of Massachusetts Medical School, Worcester, MA,
United States
454
449
LOST IN FRENCH POLYNESIA: WHICH STRATEGIES FOR A
DENGUE VIRUS TO SPREAD?
Van-Mai Cao-Lormeau, Elodie Descloux, Claudine Simone Roche,
Maite Aubry, Rémy Teyssou
Institut Louis Malardé, Papeete, French Polynesia
PROSPECTIVE STUDY OF SUB-CLINICAL DENGUE INFECTION
MEASURED BY NEUTRALIZING ANTIBODIES IN VIETNAMESE
SCHOOL CHILDREN
Christine Luxemburger1, Thi Kim Tien Nguyen2, Denis Crevat3,
Thi Que Huong Vu2, Trong Toan Nguyen2, Jean Lang4
1
sanofi pasteur Epidemiology Department, Lyon, France, 2Pasteur Institute,
Ho Chi Minh City, Vietnam, 3sanofi pasteur Research and Development
Department, Swiftwater, PA, United States, 4sanofi pasteur Research and
Development Department, Lyon, France
118
www.astmh.org
455
462
STUDY OF DENV INTERACTIONS WITH RNAI PATHWAY IN THE
MOSQUITO
EVALUATION OF MOSQUITOES AS SYRINGES FOR ARBOVIRUS
VIREMIA DETERMINATIONS IN SMALL VERTEBRATES
Irma J. Sanchez-Vargas, Alexander Franz, Valerie BarbosaSolomieu, Carol Blair, Ken Olson
Rebekah J. Kent, Nicholas Komar
456
EVALUATION OF THE PLATELIA™ DENGUE NS1 AG ELISA KIT
IN EARLY DIAGNOSIS OF DENGUE INFECTION
Vu Ti Que Huong1, Ha Van Phuc2, Huynh Thi Kim Loan1, Cao
Minh Thang1, Hoang Thi Nhu Dao1, Doan Thi Minh Tam1, Tran Thi
Ngoc Ha1
463
PREVALENCE OF HUMAN IGG ANTIBODIES AGAINST FLAVIVIRUSES IN CENTRAL AND NORTHERN AFGHANISTAN
Gerhard Dobler1, Michael Faulde2, Roman Wölfel1, Martin Pfeffer1,
Sandra Essbauer1
1
Bundeswehr Institute of Microbiology, Munich, Germany, 2Bundeswehr
Central Institute, Koblenz, Germany
1
Institut Pasteur, Ho Chi Minh City, Vietnam, 2Vinh Thuan District Hospital,
Kien Giang Province, Vietnam
DENGUE VIRUS CROSS-REACTIVE MOUSE OR HUMANIZED
CHIMPANZEE MONOCLONAL ANTIBODIES FAVOR ENHANCED
DENGUE VIRUS IMMUNE COMPLEX INFECTIVITY IN
ENGINEERED HUMAN FC GAMMA RECEPTOR CD64 OR CD32EXPRESSING CELLS
W. W. Shanaka I. Rodrigo1, Ana P. Goncalvez2, Xia Jin1, Robert C.
Rose1, Ching-Juh Lai2, Jacob J. Schlesinger1
1
University of Rochester School of Medicine and Dentistry, Rochester, NY,
United States, 2National Institutes of Health, Bethesda, MD, United States
458
COMMUNITY PARTICIPATION PROJECT FOR DENGUE PREVENTION AND CONTROL IN PUERTO RICO: KNOWLEDGE, ATTITUDES, AND PRACTICES IN 2005-2006
Aurimar Ayala-López, Carmen Pérez-Guerra
Flaviviridae – West Nile
459
RELATIONSHIPS BETWEEN COMBINED SEWER OVERFLOWS
AND WEST NILE VIRUS: SPATIAL PATTERNS OF MOSQUITO
VECTORS, AVIAN HOSTS AND HUMAN CASES IN FULTON
COUNTY, GA
Jodi Vanden Eng1, Rosmarie Kelly2, Priti Kolhe3, Steven R.
Katkowsky3, James Howgate3, Jerry Kerce3, Daniel Mead4,
Tom Burkot1
1
Georgia Division of Public Health, Atlanta, GA, United States, 3Fulton
County Department of Health and Wellness, Atlanta, GA, United States,
4
Southeastern Cooperative Wildlife Disease Study, College of Veterinary
Medicine, The University of Georgia, Athens, GA, United States
2
465
CAPTIVE ANIMALS AS SENTINELS FOR WEST NILE VIRUS
TRANSMISSION IN ZOOS FROM YUCATAN AND TABASCO
STATES OF MÉXICO
Fernando I. Puerto1, Maria A. Lorono-pino1, José A. Farfan-Ale1,
Julian E. Garcia-Rejon1, Julian E. Garcia-Rejon1, Rosa C. CetinaTrejo1, Ana C. Hidalgo-Martinez2, Celso Ramos2, Elsy del Pilar
Rosado-Paredes1, Luis F. Flores-Flores1
1
Universidad Autonoma de Yucatan, Merida, Yucatan, Mexico, 2Instituto
Nacional de Salud Publica, Cuernavaca, Morelos, Mexico
ECOLOGICAL OBSERVATIONS ON THE WEST NILE VIRUS
OUTBREAK IN DAVIS, CALIFORNIA, 2006
466
Carrie Nielsen, Sarah Wheeler, Veronica Armijos, William Reisen
GENETIC VARIABILITY OF WEST NILE VIRUS IN SENEGAL
University of California, Davis, Davis, CA, United States
Anne Dupressoir1, Pablo M de A. Zanotto2, Juliana Velasco de
Castro Oliveira2, Lang Girault1, Ousmane Faye1, Mireille Mondo1,
Yamar Ba1, Ibrahima Dia1, Mawlouth Diallo1, Amadou Alpha Sall1
460
ADIPOCYTES ARE A POTENTIAL TARGET FOR WEST NILE
VIRUS INFECTION
1
Institut Pasteur Dakar, Dakar, Senegal, 2Laboratório de Evolução Molecular
e Bioinformática, Sao Paulo, Brazil
Haiyan Luo, Bruce Cropp, James Kelley, Pratibha V. Nerurkar, Yeung
Luo, Saguna Verma, Vivek R. Nerurkar
(ACMCIP Abstract)
467
461
RAPID GIS-BASED PROFILING OF WEST NILE VIRUS TRANSMISSION: ENVIRONMENTAL FACTORS ASSOCIATED WITH AN
URBAN-SUBURBAN OUTBREAK IN NORTHEAST OHIO, USA
MULTIPLE FACTORS INFLUENCE WEST NILE VIRUS SEROPREVALENCE IN WILD MAMMALS
Andres Gomez1, A. Marm Kilpatrick2, Laura D. Kramer3, Alan P.
Dupuis3, Matthew J. Jones3, Scott J. Goetz4, Peter P. Marra5, Peter
Daszak2, A. Alonso Aguirre6
Columbia University, New York, NY, United States, 2The Consortium for
Conservation Medicine, New York, NY, United States, 3Wadsworth Center,
New York State Department of Health, Albany, NY, United States, 4Woods
Hole Research Center, Falmouth, MA, United States, 5Smithsonian Migratory
1
Case Western Reserve University, Cleveland, OH, United States, 2Cuyahoga
Bird Center, National Zoological Park, Washington, DC, United States,
6
County Board of Health, Cleveland, OH, United States
Wildlife Trust, New York, NY, United States
119
A. Desiree La Beaud1, Ann Marie Gorman1, Joseph Koonce1,
Christopher Kippes2, John McLeod2, Joseph Lynch2, Charles H.
King1, Anna M. Mandalakas1
1
Tuesday, November 6
457
464
Detailed Program
www.astmh.org
468
INTRACELLULAR LOCALIZATION, MEMBRANE ASSOCIATION
AND PROCESSING OF WNV NY99 STRAIN NS4B
Pakieli H. Kaufusi, Richard Yanagihara, Vivek R. Nerurkar
469
KNOWLEDGE, ATTITUDES, AND PRACTICES ABOUT WEST NILE
VIRUS AMONG HISPANICS IN SAN DIEGO COUNTY - 2006
Jeffrey Bethel1, Michele Ginsberg2, Stephen Waterman1
1
Centers for Disease Control and Prevention, San Diego, CA, United States,
County of San Diego Health and Human Services Agency, San Diego, CA,
United States
2
470
Kinetoplastida – Diagnosis and Treatment
474
PREPARATION AND CHARACTERIZATION OF LIVE ATTENUATED STRAIN OF L.MAJOR
Alireza Khabiri, Farideh Bagheri, Mehdi Assmar
Pasteur Institute of Iran, Tehran, Islamic Republic of Iran
475
IDENTIFICATION OF GENETIC VARIATION AND POLYMORPHISMS PRODUCING DIFFERING MULTILOCUS ENZYME ELECTROPHORESIS PATTERNS IN NEW WORLD LEISHMANIA
SPECIES
Pablo Tsukayama1, Nicolás Veland2, Jorge Arévalo2, Carmen
Lucas1, David J. Bacon1
1
PHYLOGENETIC RELATIONSHIPS OF WEST NILE VIRUS ISOLATES COLLECTED IN FLORIDA DURING 2005
Naval Medical Research Center Detachment, Lima, Peru, 2Instituto de
Medicina Tropical “Alexander von Humboldt” - Universidad Peruana
Cayetano Heredia, Lima, Peru
Daniel M. Chisenhall, Christopher N. Mores
University of Florida - Florida Medical Entomology Laboratory, Vero Beach,
FL, United States
471
OPTIMIZATION OF A CHIMERIC DEN-2/WEST NILE VACCINE
O’Neil Wiggan1, Claire Y.-H. Huang2, Shawn J. Silengo2, Richard M.
Kinney1, Jorge E. Osorio3, Dan T. Stinchcomb1
1
InViragen, Inc., Fort Collins, CO, United States, 2Division of Vector-Borne
Infectious Diseases of the Centers for Disease Control and Prevention,
Fort Collins, CO, United States, 3University of Wisconsin, Madison, WI,
United States
472
WNV-INDUCED MORBIDITY AND MORTALITY IN BALB/C MICE
Xiomara Mercado1, Yisel A. Rivera1, Elizabeth Hunsperger2,
Idali Martinez1
476
PHASE III TRIAL OF PAFURAMIDINE MALEATE (DB289), A
NOVEL ORAL DRUG, FOR TREATMENT OF FIRST STAGE SLEEPING SICKNESS
Christian Burri1, Gabriele Pohlig1, Sonja Bernhard1, Alain Mpanya
Kabeya2, Jean-Pierre Fina Lubaki3, Alfred Mpoo Mpoto3, Kambau
Manesa Gratias4, Florent Mbo Kuikumbi2, Alain Fukinsia Mintwo2,
Auguy Kayeye Munungi2, Jose Tito Bage5, Stephen Macharia6,
Constantin Miaka Bilenge2, Victor Kande Mesu2, Jose Ramon
Franco6, Ndinga Dieyi Dituvanga5, Carol A. Olson7
1
Swiss Tropical Institute, Swiss Center for International Health, Basel,
Switzerland, 2Programme Nationale de Lutte contre la Trypanosomiase
Humaine Africaine, Kinshasa, Democratic Republic of the Congo, 3Evangelic
Hospital, Vanga, Democratic Republic of the Congo, 4Evangelic Hospital,
Kikongo, Democratic Republic of the Congo, 5Instituto de Combate e de
Controlo das Tripanossomiases, Luanda, Angola, 6Malteser International, Yei,
Sudan, 7Immtech Pharmaceuticals, Inc., Vernon Hills, IL, United States
1
University of Puerto Rico Medical Sciences Campus, San Juan,
PR, United States, 2Centers for Diseases Control and Prevention, Division of
Vector-Borne Infectious Disease, Dengue Branch, San Juan, PR, United States
473
UPDATE ON THE STATUS OF THE NATIONAL WEST NILE VIRUS
INFECTION AND PREGNANCY OUTCOMES STUDY
Dawn Wesson1, Scott McRae1, Ken Swan1, Alison F. Hinckley2, Xu
Xiong1, Patricia Kissinger1, Patricia Sirois1, Edward B. Hayes2, Sonja
Rasmussen3, Stephanie Kuhn2, Dan O’Leary2, Pierre Buekens1,
Gabriella Pridjian1, Mike Henson4
1
Tulane University, New Orleans, LA, United States, 2Centers for Disease
Control and Prevention, Fort Collins, CO, United States, 3Centers for Disease
Control and Prevention, Atlanta, GA, United States, 4Purdue University,
Hammond, IN, United States
477
REPOSITIONING OF PDE TARGET CHEMISTRY TO PROMOTE
DRUG DISCOVERY FOR SLEEPING SICKNESS
Gillian E. Robbins, Robert K. Campbell
(ACMCIP Abstract)
478
AMERICAN TRYPANOSOMIASIS (CHAGAS DISEASE) AMONG
LATIN AMERICAN IMMIGRANTS IN A CARDIOLOGY CLINIC IN
LOS ANGELES, CALIFORNIA
Paul H. Nieberg1, Glenn E. Mathisen1, Sheba K. Meymandi1,
Louis V. Kirchhoff2
1
Olive View-UCLA Medical Center, Sylmar, CA, United States, 2University of
Iowa, Iowa City, IA, United States
120
479
www.astmh.org
485
THE WIDE CLINICAL SPECTRUM OF LEISHMANIA VIANNIA
BRAZILIENSIS INFECTION IN THE STATE OF CEARÁ,
NORTHEASTERN BRAZIL
USE OF GLOBAL PROTEOMICS TO DEFINE PROTEIN PROFILES
OF SEVERE DISEASE: AN INVESTIGATION ON SEVERE MALARIA
Anastacio Q. Sousa1, Telma B. Queiroz1, Margarida M. Pompeu1,
Jose W. Lima1, Richard D. Pearson2
Kenya Medical Research Institute (KEMRI)/Centre for Geographic Medicine
Research (CGMR)-Coas, Kilifi, Kenya
Evelyn N. Gitau
1
Federal University of Ceará and Hospital São José, Fortaleza, Ceará, Brazil,
University of Virginia School of Medicine, Charlottesville, VA, United States
2
480
RAPID DIAGNOSIS OF HUMAN LEISHMANIASIS SPECIES USING
A RAPID CELLULOSE ACETATE ELECTROPHORESIS (CAE)
Juan Mendez, Kashinath Ghosh, Peter J. Weina
481
(ACMCIP Abstract)
486
RECOVERY OF ENDOTHELIAL FUNCTION IN SEVERE FALCIPARUM MALARIA CORRELATES WITH RECOVERY OF PLASMA
ARGININE CONCENTRATIONS AND FALL IN BLOOD LACTATE
Tsin Yeo1, Daniel Lampah2, Retno Gitawati3, Emiliana Tjitra4,
Enny Kenangalem2, Yvette McNeil1, Don Granger5, Bert Lopansri5,
Brice Weinberg6, Ric Price1, Steve Duffull7, David Celermajer8,
Nick Anstey1
Pascal P.L. Lutumba1, Filip Meheus2, Jo Robays1, Constantin
Miaka3, Victor Kande4, Philippe Büscher1, Bruno Dujardin5, Marleen
Boelaert1
1
Institute of Tropical Medicine, Antwerp, Belgium, 2Royal Tropical Institute
(KIT), Amsterdam, Netherlands Antilles, 3Ministry of Health, Kinshasa,
Democratic Republic of the Congo, 4National Control Program against
Human African Trypanosomiasis, Kinshasa, Democratic Republic of the
Congo, 5Ecole de santé publique/Université libre de Bruxelles, Brussels,
Belgium
482
CANINE VISCERAL LEISHMANIASIS DIAGNOSIS IN BRASIL
Wilma A. Buzetti1, Nina Mari Queiroz1, Rita de Cassia Viveiros1,
Karen Ingrid Tasca1, Flavia Luna Lima1, Juliana de Assis1, Michely S.
Tenorio1, Rosangela Zacarias Machado2, Tricia Maria Oliveira2
1
UNESP, Ilha Solteira, SP, Brazil, 2UNESP, Jaboticabal, SP, Brazil
(ACMCIP Abstract)
483
Menzies School of Health Research, Darwin, Australia, 2Menzies School of
Health Research-National Institute of Health Research and Development
Research Program, Timika, Papua, Indonesia, 3National Institute of Health
Research and Development, Jakarta, Indonesia, 4National Institute of Health
Research and Development, Darwin, Indonesia, 5University of Utah, Salt
Lake City, UT, United States, 6Duke and VA Medical Centers, Durham, NC,
United States, 7University of Otago, Dunedin, New Zealand, 8University of
Sydney, Sydney, Australia
487
ENDOGENOUS NITRIC OXIDE PRODUCTION IN INTRAERYTHROCYTIC STAGES OF THE MALARIA PARASITE
Graciela R. Ostera, Fuyuki Tokumasu, James A. Dvorak
488
MOLECULAR BASIS OF PLASMODIUM FALCIPARUM
RECEPTOR BAEBL FOR BINDING TO ERYTHROCYTE
LIGAND GLYCOPHORIN C
Lubin Jiang, Sai Duriseti, Peter Sun, Louis H. Miller
DEVELOPMENT OF A FIELD-USABLE ASSAY FOR DETECTION
OF LEISHMANIA PARASITES IN SAND FLIES
Kirti Dave1, Adeline S. Chan2, Derek Smith2, Sonia Dave1, Ioana
Brasov2, Russell E. Coleman2, Edgar D. Rowton2
(ACMCIP Abstract)
VecTOR Test Systems Inc, Thousand Oaks, CA, United States, 2Department
of Entomology, Walter Reed Army Institute of Research, Silver Spring, MD,
United States
489
1
484
CHITINASE: ACTIVE RECOMBINANT PROTEIN FROM
PLASMODIUM VIVAX
Satoru Takeo1, Daisuke Hisamori1, Shusaku Matsuda1, Joseph
Vinetz2, Jetsumon Sattabongkot3, Takafumi Tsuboi1
DIFFERENTIAL IN VIVO AND IN VITRO EXPRESSION OF
MAESTRO PREDICTED MITOCHONDRIAL PROTEINS IN
Carolyn Dong1, Sarah Calvo2, Johanna Daily1, Daouda Ndiaye3,
Vamsi Mootha2, Dyann Wirth1
1
Department of Immunology and Infectious Disease, Harvard School of
Public Health, Boston, MA, United States, 2Broad Institute of Harvard and
MIT, Cambridge, MA, United States, 3Department of Parasitology and
Mycology, Dantec Hospital, Cheikh Anta Diop University, Dakar, Senegal
1
Ehime University, Matsuyama, Japan, 2Division of Infectious Diseases,
University of California at San Diego, La Jolla, CA, United States, 3United
States Army Medical Component-Armed Forces Research Institute of the
121
Tuesday, November 6
1
COST-EFFECTIVENESS OF ALGORITHMS FOR POPULATION
SCREENING OF HUMAN AFRICAN TRYPANOSOMIASIS
Detailed Program
www.astmh.org
490
496
THE PLASMODIUM SPOROZOITE AND ERYTHROCYTIC STAGE
(SES) PROTEIN HAS A UNIQUE SURFACE LABELING PATTERN
ON THE SPOROZOITE AND APPEARS TO PLAY A ROLE IN
SPOROZOITE INVASION OF MOSQUITO SALIVARY GLANDS
Alexis N. LaCrue, Roy J. Lowery, Renee N. Roberts, Michael M.
Kariuki, Brenda T. Beerntsen
EFFICACY OF NON-CONTROLLED INTERMITTENT PREVENTIVE
TREATMENT IN PREGNANT (IPTP) WOMEN IN CÔTE D’IVOIRE
Toure A. Offianan1, Berenger Aristide Ako1, Louis Kone Penali1,
Messoum Nogbou2, Tidjane Swa3, Bernadin B1, Bernadin Gba4,
Soumahoro Adama1, Issiaka Bassirika1
1
Pasteur Institute, Abidjan, Cote d’Ivoire, 2Maternity Yopougon, Abidjan,
Cote d’Ivoire, 3Maternity Yopougon, Abidjan, Cote d’Ivoire, 4General
Hospital, Bonoua, Cote d’Ivoire
491
497
A CHEMICAL BIOLOGY APPROACH TO UNDERSTAND
CYSTEINE PROTEASE FUNCTION IN P. FALCIPARUM
USING SMOOTHED GROWTH CURVES FROM ANTHROPOMETRIC
REFERENCE POPULATIONS IN MALARIA ENDEMIC COUNTRIES TO
DESIGN AGE- AND HEIGHT-BASED ALTERNATIVES TO WEIGHTBASED DOSING FOR ARTEMISININ-BASED COMBINATIONS IN
THE TREATMENT OF UNCOMPLICATED FALCIPARUM MALARIA
Doron Greenbaum
492
IMPACT OF REPEATED ADMINISTRATION OF ACTS ON ANEMIA AND ANTIMALARIAL IMMUNITY IN MALI
1
1
1
1
Sekou Toure , Bakary Fofana , Issaka Sagara , Bakary Sidibe ,
Demba Dembele1, Amadou Togo1, Alassane Dicko1, Christopher V.
Plowe2, Ogobara K. Doumbo1, Abdoulaye A. Djimde1
1
University of Bamako, Bamako, Mali, 2University of Maryland, Baltimore,
MD, United States
493
ANALYSIS OF PFE0565W AND PF11_0394, TWO PLASMODIUM
FALCIPARUM SPOROZOITE GENES
Maggie Schlarman, Michael Kariuki, Alexis LaCrue, Ruguang Ou,
Brenda Beerntsen
Dianne J. Terlouw1, Daniel J. Hayes1, Stef van Buuren2, Isabela
Ribeiro3, Piero L. Olliaro4, Feiko O. ter Kuile1
1
Liverpool School of Tropical Medicine, Liverpool, United Kingdom, 2The
Netherlands Organization for Applied Scientific Research (TNO), Leiden, The
Netherlands, 3Drugs for Neglected Diseases Initiative, Geneva, Switzerland,
4
World Health Organization Special Programme for Research and Training in
Tropical Diseases/Product Research and Development, Geneva, Switzerland
498
‘MALARIA DISCIPLINE’ AND NEUROPSYCHIATRIC CASES
AMONG US TROOPS IN SE ASIA: 1960-1975
David P. Adams
London School of Hygiene and Tropical Medicine, Savannah, GA, United
States
Malaria - Chemotherapy
494
COMPARISON OF CHLORPROGUANIL-DAPSONE WITH A COMBINATION OF CHLOROQUINE AND SULFADOXINEPYRIMETHAMINE IN CHILDREN WITH MALARIA IN JOS,
NIGERIA
Ogunfowokan Paul Oluwagbenga1, Dankyau Musa2,
Madaki J. Aboi1
1
Jos University Teaching Hospital, Jos, Nigeria, 2ECWA Evangel Hospital Jos,
Nigeria
499
QUALITY OF ANTIMALARIAL DRUGS SOLD AT RETAIL OUTLETS IN TANZANIA, 2005. RESULTS OF A NATIONALLY REPRESENTATIVE SURVEY
Harparkash Kaur1, Catherine Goodman2, Irene Masanja3, Eloise
Thompson1, Katy-Anne Thompson1, S. Patrick Kachur4
1
Kingdom, 2KEMRI/Wellcome Collaborative Programme, Nairobi, Kenya,
3
GA, United States
500
495
COMPARATIVE EFFICACY OF AN ARTEMISININ COMBINATION
THERAPY (ACT) AND A NON-ARTEMISININ COMBINATION
THERAPY IN THE MANAGEMENT OF UNCOMPLICATED
FALCIPARUM MALARIA IN IBADAN, NIGERIA
Hannah O. Dada-Adegbola, Olusegun G. Ademowo,
Cathrine O. Falade
College of Medicine, University of Ibadan, Ibadan, Nigeria
HIV-1 INHIBITORS AND MALARIA
Tina S. Skinner-Adams
501
MURINE MALARIA TREATMENT MODEL FOR ANTIMALARIAL
COMBINATIONS
Kevin T. Batty1, Brioni R. Moore1, Christopher Andrzejewski1,
Jillian R. Stoney1, Angela S. Law1, Jeffrey D. Jago1, Peter L.
Gibbons1, Kenneth F. Ilett2
1
Curtin University of Technology, Perth, Australia, 2University of Western
Australia, Perth, Australia
122
502
www.astmh.org
507
MEFLOQUINE-INDUCED DISRUPTION OF CALCIUM HOMEOSTASIS IN MAMMALIAN CELLS MAY BE DUE TO AN
IONOPHORIC EFFECT SIMILAR TO THAT OF IONOMYCIN
ACUTE RESPIRATORY DISTRESS SYNDROME DUE TO VIVAX
MALARIA SUCCESSFULLY TREATED WITH EXCHANGE
TRANSFUSION
Diana Caridha, Debra Yourick, Tom Hudson, Geoffrey S. Dow
Andrew Nguyen, Victor Jimenez, Rodrick Go
Stony Brook University Medical Center and Northport Veterans Affairs
Medical Center, Stony Brook, NY, United States
508
503
IN SILICO PHARMACOPHORE FOR ANTIMALARIAL ACTIVITY
OF THE 4(1H)-QUINOLONES TO AID DISCOVERY OF NOVEL
CAUSAL PROPHYLACTIC DRUG CANDIDATES
LACK OF BENEFIT FROM ANTIMALARIAL TREATMENT TO
CLEAR P. FALCIPARUM PARASITEMIA IN THE NORTH
SAVANNA REGION OF MALI
Apurba K. Bhattacharjee1, Lucia Gerena1, Montip Gettyacamin2,
Kevin Pitzer1, Wilbur K. Milhous1, Dennis E. Kyle1
Mamadou Weleba Bagayoko1, Ousmane Aliou Koita1, Aliou
Coulibaly2, Aliou Sissako1, Mamadou M. Keita2, Sidy Sidy1, Salif
Mangara1, Youssouf Samake1, Boubacar Diallo1, Lansana Sangare1,
Ibrahim Dolo1, Donald J. Krogstad3
1
Division of Experimental Therapeutics, Walter Reed Army Institute of
Research, Silver Spring, MD, United States, 2Department of Veterinary
Medicine, Armed Forces Research Institute for the Medical Sciences,
Bangkok, Thailand
1
Faculty of Science, University of Bamako, Bamako, Mali, 2Faculty of
Medicine, University of Bamako, Mali, 3School of Public Health and Tropical
Medicine, Tulane University, LA, United States
504
510
ASSESSMENT OF THE EFFECTIVENESS OF ARTEMETHER PLUS
LUMEFANTRINE VERSUS ARTESUNATE PLUS AMODIAQUINE
FOR THE TREATMENT OF CHILDREN WITH UNCOMPLICATED
PLASMODIUM FALCIPARUM MALARIA
STUDY DESIGN FOR ANTIMALARIAL DEVELOPMENT:
INCREASING THE EFFICIENCY OF PHASE II EFFICACY STUDIES
IN HUMAN SUBJECTS
Samuel Adjei
Fawaz Mzayek1, Ousmane A. Koita2, Aliou Sissako2, Seydou O.
Doumbia2, Donald J. Krogstad1
Ghana Health Service, Agona-Ash, Ghana
505
1
Tulane University Health Sciences Center, New Orleans, LA, United States,
2
EVIDENCE FOR THE NON-ESSENTIALITY OF THE PLASMODIUM
CANDIDATE DRUG TARGET ENOYL ACP REDUCTASE
Min Yu1, T. R. Santha Kumar2, Louis J. Nkrumah2, Photini Sinnis3,
Alida Coppi3, Juan-Carlos Valderramos1, Paul Gatraud4, Laurent
Kremer4, Catherine Vilcheze2, Guy A. Schiehser5, David P. Jacobus5,
Joel S. Freundlich6, Alfonso Mendoza7, José-Francisco Garcia
Bustos7, William R. Jacobs Jr.8, James C. Sacchettini9,
David A. Fidock1
DIFFERENT APPROACHES TO THE EXOERYTHROCYTIC MODEL
FOR HUMAN MALARIA IN MICE
1
Columbia University, New York, NY, United States, 2Albert Einstein College
of Medicine, Bronx, NY, United States, 3New York University, New York, NY,
United States, 4Universite Montpellier II, Montpellier, France, 5Jacobus
Pharmaceuticals, Princeton, NJ, United States, 6Princeton University,
Princeton, NJ, United States, 7GlaxoSmithKline, Tres Cantos, Spain, 8Howard
Hughes Medical Institute, Albert Einstein College of Medicine, Bronx, NY,
United States, 9Texas A&M University, College Station, TX, United States
506
DISPOSITION OF ARTESUNATE AND MEFLOQUINE (ASMQ)
AFTER ADMINISTRATION AS LOOSE (L) AND FIXED-DOSE
COMBINATION (F) TO ADULT THAI HEALTHY VOLUNTEERS
AND UNCOMPLICATED FALCIPARUM MALARIA PATIENTS
Vis Navaratnam1, Sornchai Looareesuwan2, Surash Ramanathan1,
Sharif Mansor1, Jean-René Kiechel3, Michel Vaillant4, Walter (Bob) R.
Taylor5, Piero L. Olliaro6
511
P. Castañeda, J. Pinel, I. Camino, MJA Almela, S. Lozano, E. Alonso,
D. Gargallo, Elena Jiménez
GlaxoSmithKline, Tres Cantos, Spain
(ACMCIP Abstract)
512
PRELIMINARY PHARMACOKINETIC/PHARMACODYNAMIC
STUDY OF 4(1H)-PYRIDONE GW308678 IN A MURINE
PLASMODIUM YOELII MODEL OF MALARIA
Adolfo García-Pérez, Belén Jiménez-Díaz, Beatriz Rodríguez, Angela
Alvarez, Teresa Mulet, Sara Viera, Vanesa Gómez, Helena Garuti,
Alejandra Fernández, Eduardo Romanos, Iñigo Angulo-Barturen,
Santiago Ferrer, Domingo Gargallo
(ACMCIP Abstract)
1
National Centre For Drug Research, Universiti Sains Malaysia (USM), Pulau
Pinang, Malaysia, 2Mahidol University, Bangkok, Thailand, 3Drugs for
Neglected Diseases initiative (DNDi), Geneva, Switzerland, 4Centre de
Recherches Publiques (CRP)- Santé, Luxembourg, Luxembourg, 5Oxford
University - National Institute of Infectious and Tropical Diseases, Hanoi,
Vietnam, 6World Health Organization (WHO) Special Programme for
Research and Training in Tropical Diseases (TDR), Geneva, Switzerland
123
Tuesday, November 6
(ACMCIP Abstract)
Detailed Program
www.astmh.org
513
519
ANALYSIS OF PLASMODIUM-STAGE POPULATION DISTRIBUTION IN MURINE MODELS OF MALARIA BY FLOW CYTOMETRY USING AUTOFLUORESCENCE AND YOYO-1
PREDICTORS OF OUTCOME IN THE PHASE II TRIAL OF DB289
AND ARTESUNATE FOR THE TREATMENT OF UNCOMPLICATED
Belén Jiménez-Díaz, Angela Alvarez, Teresa Mulet, Sara Viera,
Vanesa Gómez, Helena Garuti, Alejandra Fernández, Carmen Bravo,
Domingo Gargallo, Iñigo Angulo-Barturen
L. Kalilani1, C. Olson2, D. Morris3, J. Isaacson3, N. Tangpukdee4, S.
Krudsood4, S. Looareesuwan4, J. Longstreth5, S. Meshnick6
(ACMCIP Abstract)
514
1
University of Malawi, College of Medicine, Blantyre, Malawi, 2Immitech
Pharmaceuticals Inc, Vernon Hills, IL, United States, 3WebbWrites, Durham,
NC, United States, 4Hospital for Tropical Diseases, Faculty of Tropical
Medicine, Mahidol University, Bangkok, Thailand, 5Longstreth Associates,
Mundelein, IL, United States, 6University of North Carolina, Chapel Hill, NC,
United States
CROSSOVER TRIAL TO TEST A 2100 MG DOSE OF AQ-13 AND
THE EFFECT OF FOOD ON ITS BIOAVAILABILITY
Fawaz Mzayek, Haiyan Deng, Azam Hadi, Juan J. Lertora, Donald
J. Krogstad
Tulane University, New Orleans, LA, United States
515
NOVEL IN VITRO CULTURE OF LIVER STAGE HUMAN MALARIA
FOR SCREENING OF NEW ANTI-MALARIAL COMPOUNDS
1
1
Rachaneeporn Jenwithisuk , Ratawan Ubalee , Panadda
Krairojananan1, Wachira Suktawonjaroenpon1, Bousaraporn
Tippayachai1, Nongnuch Yimamnuaychok1, Nattawan
Rachaphaew1, Chulaluck Charurojpakorn1, Namtip Trongnipatt1,
Ampornpan Kengluecha1, Surasak Leelaudomlipi2, Kesinee
Chotivanich3, Rachanee Udomsangpetch4, Jetsumon Sattabongkot1
520
PHASE 1 INVESTIGATION TO ASSESS THE RENAL AND
OPTHALMIC EFFECTS OF TAFENOQUINE, A NOVEL ANTIMALARIAL DRUG
Kevin Leary1, D. Craig Brater2, Corina van de Pol3, Khadeeja
Pruett4, Caron Kerr4, James Veazey5, Nagercoil Nithyanandan6,
Colin Ohrt7
1
Uniformed Services University of Health Sciences, Bethesda, MD, United
States, 2Indiana University School of Medicine, Indianapolis, IN, United
States, 3AcuFocus, Inc., Irvine, CA, United States, 4GlaxoSmithKline, Upper
Providence, United Kingdom, 5U.S. Army Medical Materiel Development
Activity, Fort Detrick, MD, United States, 6CCRU, Berkshire, United Kingdom,
7
Malaria – Drug Resistance
1
Medical Sciences, Bangkok, Thailand, 2Faculty of Medicine, Ramathibodi
Hospital, Mahidol University, Bangkok, Thailand, 3Faculty of Tropical
Medicine, Mahidol University, Bangkok, Thailand, 4Faculty of Science,
516
521
DETECTION OF CHLOROQUINE RESISTANCE IN P.
FALCIPARUM: EVALUATION OF MOLECULAR MARKERS IN
CLINICAL ISOLATES FROM NORTHEAST INDIA
PURINE TRANSPORT IN PLASMODIUM FALCIPARUM
Mohan L. Dubey1, Sandeep K. Shrivastava1, J. Mahanta2, Nancy
Malla1, R. C. Mahajan1
Neils B. Quashie, Lisa Ranford-Cartwright, Harry de Koning
1
Insitute of Biomedical and Life Sciences, University of Glasgow, Glasgow,
United Kingdom
Department of Parasitology, Postgraduate Institute of Medical Education
and Research, Chandigarh, India, 2Regional Medical Research Centre (ICMR),
Dibrugarh, Assam, India
517
522
SAFETY ASSESSMENT OF AZITHROMYCIN PLUS CHLOROQUINE FOR THE TREATMENT AND PREVENTION OF MALARIA
RESPONSE OF FALCIPARUM MALARIAL PARASITE TO STANDARD TEST DOSE OF CHLOROQUINE IN PUNJAB, PAKISTAN
Larry Ritzhaupt1, Beverly A. Betley1, Damien Hirsch2, Donald R.
Jaffe1, Drew Lewis1, William McConnell1, Liz Mridha3, Konrad
Tomaszewski3, Cynthia de Luise2
Saleem M. Rana
1
Pfizer Inc, New London, CT, United States, 2Pfizer Inc., New York, NY,
United States, 3Pfizer Inc., Sandwich, United Kingdom
518
DIFFERENTIAL EFFECTS OF CYSTEINE PROTEASE INHIBITORS
ON PLASMODIUM FALCIPARUM SEXUAL STAGE PARASITES
Saliha Eksi, Beata Czesny, Samrawit Goshu, Kim C. Williamson
Loyola University Chicago, Chicago, IL, United States
(ACMCIP Abstract)
Directorate General Health Services Punjab, Lahore, Pakistan
523
RAPID DETECTION OF DIHYDROFOLATE REDUCTASE RESISTANCE ALLELES IN PLASMODIUM FALCIPARUM USING REALTIME PCR WITH LOCKED NUCLEIC ACID TAQMAN PROBES
Olusola Ojurongbe1, Adetayo F. Fagbenro-Beyioku2, Juergen F.
Kun3, Peter G. Kremsner3
1
Ladoke Akintola University of Technology, Osogbo, Osun State, Nigeria,
College of Medicine, University of Lagos, Idi Araba, Lagos, Nigeria,
3
Institute of Tropical Medicine, University of Tuebingen, Tuebingen, Germany
2
124
524
528
CLEARANCE OF AMODIAQUINE-RESISTANT PLASMODIUM
FALCIPARUM IN NIGERIAN CHILDREN BY IMMUNOGLOBULIN
G ANTIBODIES TO THE 19-KDA C-TERMINAL REGION OF
MEROZOITE SURFACE PROTEIN 1 (MSP-119)
1
1
Onikepe A. Folarin , Christian T. Happi , Grace O. Gbotosho ,
Chiaka Anumudu2, Dare O. Idowu2, Akintunde Sowunmi1, RoseAngela Nwugba2, Olufunsho O. Olorunsogo3, Wilbur Milhous4,
Dyann F. Wirth5, Ayoade M. Oduola6
1
Malaria Research Lab, Institute of Advanced Medical Research and Training,
College of Medicine, University of Ibadan, Ibadan, Nigeria, 2Department of
Zoology, University of Ibadan, Ibadan, Nigeria, 3Department of Biochemistry,
University of Ibadan, Ibadan, Nigeria, 4Division of Experimental Therapeutics,
5
Department of Immunology and Infectious Diseases, Harvard School of
Public Health, Boston, MA, United States, 6Special Programme for Research
and Training in Tropical Diseases (WHO/TDR), Geneva, Switzerland
Mohammad T. Alam1, Sumiti Vinayak1, Hema Bora1, Manoj K.
Das2, Neeru Singh3, Aditya P. Dash4, Yagya D. Sharma1
1
All India Institute of Medical Sciences, New Delhi, India, 2National Institute
of Malaria Research (Field Station), Ranchi, India, 3National Institute of
Malaria Research (Field Station), Jabalpur, India, 4National Institute of
Malaria Research, Delhi, India
529
CONSUMER PERCEPTIONS AND CARE-SEEKING FOR FEBRILE
ILLNESS ASSOCIATED WITH THE AVAILABILITY OF
ARTEMISININ-CONTAINING ANTIMALARIAL COMBINATION
THERAPY IN RUFIJI DISTRICT TANZANIA, 2003 TO 2006
S. Patrick Kachur1, Berty F. Elling2, Emmy O. Metta2, Rashid A.
Khatib2, Rene P. Gerrets3, Peter B. Bloland1, Salim Abdulla2
(ACMCIP Abstract)
525
1
IDENTIFICATION OF SINGLE NUCLEOTIDE POLYMORPHISMS
(SNPS) IN PLASMODIUM FALCIPARUM DHFR, PFDHPS AND
PFCRT GENES USING A MICROSPHERE-BASED MINISEQUENCING ASSAY
Carola J. Salas, Stella M. Chenet, David J. Bacon
Republic of Tanzania, 3New York University, New York, NY, United States
2
530
EXPANDED SURVEILLANCE TO CONFIRM THE DISAPPEARANCE
OF CHLOROQUINE RESISTANT MALARIA FOLLOWING
CHLOROQUINE WITHDRAWAL IN MALAWI
US Naval Medical Research Center Detachment, Lima, Peru
(ACMCIP Abstract)
526
MUTATIONAL ANALYSIS OF THE DIHYDROFOLATE REDUCTASE
AND DIHYDROPTEROATE SYNTHASE GENES FROM
PLASMODIUM VIVAX IN ISOLATES FROM IQUITOS, PERU
Meddly L. Santolalla, Carola J. Salas, Carmen Lucas,
David J. Bacon
(ACMCIP Abstract)
Fraction K. Dzinjalamala1, Miriam K. Laufer2, Nicholas Connors3,
Rachel Bronzan3, Shannon L. Takala2, Malcolm E. Molyneux4, Grace
Malenga5, Terrie E. Taylor6, Christopher V. Plowe2
1
University of Malawi College of Medicine, Blantyre, Malawi, 2University of
Maryland School of Medicine, Baltimore, MD, United States, 3Blantyre
Malaria Project, Blantyre, Malawi, 4Malawi-Liverpool-Wellcome Trust Clinical
Research Programme, Blantyre, Malawi, 5Malaria Alert Center, Blantyre,
Malawi, 6Blantyre Malaria Project and Michigan State University, Blantyre,
Malawi
(ACMCIP Abstract)
527
531
SELECTION OF PLASMODIUM FALCIPARUM MULTIDRUG
RESISTANCE GENE 1 ALLELES BY ARTEMETHERLUMEFANTRINE IN NIGERIAN CHILDREN WITH ACUTE
UNCOMPLICATED MALARIA
1
CHARACTERIZATION OF FOUR MICROSATELLITES AROUND
PLASMODIUM VIVAX DIHYDROFOLATE REDUCATSE (PVDHFR)
GENE ASSOCIATED WITH PYRIMETHAMINE RESISTANCE
2
DNA MISMATCH REPAIR IN PLASMODIUM FALCIPARUM:
POSSIBLE MECHANISM FOR ACCELERATED DRUG RESISTANCE
Meryl Castellini, Jeff Buguliskis, Theodore F. Taraschi
2
Christian T. Happi , Grace O. Gbotosho , Onikepe A. Folarin ,
Akintunde Sowunmi2, Ahmed A. Adedeji2, O. M. Bolaji2, T.
Balogun2, Wilbur Milhous3, Dyann F. Wirth1, Ayoade M. Oduola4
1
Harvard School of Public Health, Boston, MA, United States, 2Malaria
Research Lab, Institute of Advanced Medical Research and Training, College
of Medicine, University of Ibadan, Ibadan, Nigeria, 3Division of Experimental
Therapeutics, Walter Reed Army Institute of Research, Silver Spring, MD,
United States, 4Special Programme for Research and Training in Tropical
Diseases (WHO/TDR), Geneva, Switzerland
532
A TWO-STAGE MODEL OF MALARIA TRANSMISSION AND ITS
IMPACT ON THE SPREAD OF RESISTANCE
David L. Smith1, Maciej Boni2, Eili Klein2, Ramanan Laxminarayan2
1
Fogarty International Center, National Institutes of Health, Bethesda, MD,
United States, 2Resources for the Future, Washington, DC, United States
125
Tuesday, November 6
1
www.astmh.org
Detailed Program
www.astmh.org
533
ASSESSING THE ORIGIN AND SPREAD OF DIHYDROFOLATE
REDUCTASE AND DIHYDROPTEROATE SYNTHASE MUTANT
ALLELES IN PLASMODIUM VIVAX POPULATIONS
539
TRENDS IN MALARIA DISEASE BURDEN AT HEALTH FACILITIES
IN ZAMBIA
Vivian N, Hawkins, Stephanie Suzuki, Carol Hopkins Sibley
Busiku Hamainza, Pascalina Chanda, Hawela Moonga, Elizabeth
K. Chizema
National Malaria Control Center, Lusaka, Zambia
540
(ACMCIP Abstract)
534
A DECISION TREE MODEL FOR ESTIMATING THE COST-EFFECTIVENESS OF RECTAL ARTESUNATE TREATMENT FOR SEVERE
CHILDHOOD MALARIA AT THE COMMUNITY LEVEL
MATHEMATICAL MODELS OF IN-HOST MALARIA REGULATION, AND INDIVIDUAL BASED APPROACH TO COMMUNITY
TRANSMISSION IN HETEROGENEOUS ENVIRONMENT
David E. Gurarie, Peter A. Zimmerman, Charles H. King, Drew
Kouri, Peter Thomas
Yesim Tozan1, Joel G. Breman2
541
1
The Earth Institute, Columbia University, New York, New York; Fogarty
International Center, National Institutes of Health, Bethesda, MD, United
States, 2Fogarty International Center, National Institutes of Health, Bethesda,
MD, United States
535
KNOWLEDGE, AVAILABILITY AND UTILIZATION OF MALARIA
PREVENTION MEASURES DURING PREGNANCY IN
JHARKHAND, INDIA
Blair J. Wylie1, Neeru Singh2, Jordan Tuchman1, Lora Sabin1, Kojo
Yeboah-Antwi1, Mrigendra P. Singh2, William B MacLeod1,
Mohammed Brooks1, Megnha Desai3, Venkatachalam
Udhayakumar3, Aditya P. Dash4, Davidson H. Hamer1
1
Center for International Health and Development, Boston University,
Boston, MA, United States, 2National Institute for Malaria Research Field
Station, Jabalpur, India, 3Malaria Branch, Centers for Disease Control and
Prevention, Atlanta, GA, United States, 4National Institute for Malaria
Research, Delhi, India
537
EFFECTIVENESS OF FREE AND MARKET-BASED DISTRIBUTION
STRATEGIES FOR ACHIEVING COMMUNITY-WIDE COVERAGE
AND PROTECTION WITH INSECTICIDE-TREATED NETS IN
RURAL TANZANIA
Rashid A. Khatib1, Berty F. Elling1, Gerard F. Killeen2, Salim
Abdulla1, S. Patrick Kachur3
1
Republic of Tanzania, 2University of Durham, Durham, United Kingdom,
3
538
PATIENT-TO-PATIENT TRANSMISSION OF NOSOCOMIAL
MALARIA IN KOREA
Jung-Yeon Kim1, Jeong-Su Kim2, Mi-Hyun Park1, Shin-Hyeong
Cho1, Yeon-Joo Kim1, Byung-Chul Lee1, Young-A Kang3, JoonWook Kwon4, Tong-Soo Kim1
1
Division of Malaria and Parasitic Diseases, National Institute of Health,
KCDC, Seoul, Republic of Korea, 2Epidemic Intelligence Service Officer in
Busan Metropolitan City, Busan, Republic of Korea, 3Division of Epidemic
Intelligence Service, KCDC, Seoul, Republic of Korea, 4Division of
Communicable Disease, KCDC, Seoul, Republic of Korea
HUMAN RESERVOIR OF PLASMODIUM VIVAX IN THE LOW
TRANSMISSION VILLAGE OF PERUVIAN AMAZON
Pablo P. Yori1, Margaret Kosek1, Ryan Matson2, Robert H. Gilman1,
Maribel Paredes3, Silvia Rengifo3, Cesar A. Banda3, Raul
Chuquiyauri4, Joseph Vinetz2
1
States, 2University of California in San Diego, San Diego, CA, United States,
3
Asociacion Benefica Prisma, Iquitos, Peru, 4Universidad Peruana Cayetano
Heredia, Lima, Peru
542
LIMITED SEQUENCE VARIATION IN THE PLASMODIUM FALCIPARUM SPOROZOITE THREONINE-ASPARAGINE-RICH PROTEIN
AMONG CLINICAL ISOLATES
Somchai Jongwutiwes1, Kriangkrai Karnchaisri1, Sunee
Seethamchai2, Chaturong Putaporntip1
1
Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand, 2Faculty
of Science, Naresuan University, Pitsanulok Province, Thailand
(ACMCIP Abstract)
543
DETERMINANTS OF INSECTICIDE-TREAT NET (ITN) USE
AMONG CHILDREN UNDER FIVE YEARS OF AGE IN ZAMBIA:
RESULTS OF A NATIONAL MALARIA INDICATOR SURVEY
John M. Miller1, Amara L. Robinson2, Chilandu Mukuka3,
Abdirahaman Mohamed1, Eric Seiber4, Pascalina Chanda3, Pauline
Wamalume3, Richard W. Steketee1
1
PATH, Seattle, WA, United States, 2Consultant, Lusaka, Zambia, 3Zambia
Ministry of Health, Lusaka, Zambia, 4Ohio State University, Columbus, OH,
United States
544
TREATMENT SEEKING BEHAVIOR OF PATIENTS WITH P. FALCIPARUM OR P. VIVAX INFECTION IN PAPUA, INDONESIA
M. Karyana1, L. Burdan2, E. Kenangalem2, R. Vemuri3, N.M.
Anstey4, E. Tjitra1, R.N. Price4
1
National Institute of Health Research and Development, Jakarta, Indonesia,
Dinas Kesehatan Kabupaten, Timika, Indonesia, 3Charles Darwin University,
Darwin, Australia, 4Menzies School of Health Research, Darwin, Australia
2
126
545
www.astmh.org
549
MORPHOLOGIC AND MOLECULAR ANALYSIS OF MALARIA
AND MALARIA-LIKE PARASITES IN WILD MACAQUES, SOUTHERN THAILAND
DECREASED IL-10 PRODUCTION IS ASSOCIATED WITH LYMPHOCYTOSIS IN CHILDREN WITH SEVERE MALARIAL ANEMIA
Sunee Seethamchai , Somchai Jongwutiwes , Suchinda
Malaivichitnond3, Liwang Cui4, Chaturong Putaporntip2
Yamo Ouma1, Christopher Keller2, Gordon Awandare3, Collins
Ouma1, Richard Otieno1, Tom Were1, John Vulule4, Z. Ng’ang’a5,
Gregory Davenport3, John Michael Ong’echa1, Douglas Perkins3
1
1
1
2
Department of Biology, Faculty of Science, Naresuan University, Pitsanulok,
Thailand, 2Department of Parasitology, Faculty of Medicine, Chulalongkorn
University, Bangkok, Thailand, 3Department of Biology, Faculty of Science,
Chulalongkorn University, Bangkok, Thailand, 4Department of Entomology,
The Pennsylvania State University, University Park, PA, United States
University of Pittsburgh/KEMRI, Kisumu, Kenya, 2University of
Pittsburgh/Lake Erie College of Osteopathic Medicine, Pittsburgh, PA, United
States, 3University of Pittsburgh, Pittsburgh, PA, United States, 4KEMRI,
Kisumu, Kenya, 5Kenyatta University, Nairobi, Kenya
550
(ACMCIP Abstract)
BEDNET OWNERSHIP IN KENYA: THE IMPACT OF 3.4 MILLION
FREE NETS
Willis Akhwale1, Rebecca Kiptui1, Ayub Manya1, Allen Hightower2,
Adam Wolkon3, Jodi Vanden Eng4, Mary Hamel5, Abdisalan Noor6,
Abdisalan Noor6, S.K. Sharif7, Robert Buluma8, Abdulkadir A.
Awes8, John Vulule9, Kayla Laserson5, Laurence Slutsker3,
Laurence Slutsker3
1
Division of Malaria Control, Ministry of Health, Nairobi, Kenya, 2Centers for
Disease Control and Prevention-Kenya, Nairobi, Kenya, 3Malaria Branch,
4
Atlanta, GA, United States, 5Centers for Disease Control and PreventionKenya, Kisumu, Kenya, 6KEMRI- University of Oxford - Wellcome Trust
Collaborative Programme, Nairobi, Kenya, 7Ministry of Health, Nairobi,
Kenya, 8Kenya National Bureau of Statistics, Nairobi, Kenya, 9KEMRI, Centre
for Global Health Research, Kisumu, Kenya
Malaria - Immunology
547
EVALUATION OF OXIDATIVE STRESS AND ANTI-MSP1-19
IMMUNOGLOBIN G RESPONSE TO MALARIA INFECTION IN
PREGNANCY
George O. Ademowo1, Mathew O. Akanbi2, Cathrine O. Falade1,
Alex A. Odaibo3
College of Medicine, University of Ibadan, Ibadan, Nigeria, 2Department of
Environmental Biology and Fisheries, Adekunle Ajasin University, Akungba,
Nigeria, 3Department of Zoology, Parasitology Unit, University of Ibadan,
Ibadan, Nigeria
THE ROLE OF PFRH INVASION LIGANDS AS TARGETS OF ANTIBODIES THAT PROTECT AGAINST P. FALCIPARUM MALARIA
Linda Reiling1, Jack S. Richards1, Fiona J. MacCallum1, Kristina E.
Persson1, Katherine Howell1, Sam Kinyanjui2, Kevin Marsh2, Ivo
Mueller3, Alan F. Cowman1, James G. Beeson1
1
The Walter and Eliza Hall Institute of Medical Research, Melbourne,
Australia, 2Centre for Geographic Medicine Research, Kenya Medical
Research Institute, Kilifi, Kenya, 3Papua New Guinea Institute of Medical
Research, Goroka, Eastern Highlands Province, Papua New Guinea
(ACMCIP Abstract)
551
THE IMPORTANCE OF THE ANTIBODY ISOTYPE RESPONSE TO
P. FALCIPARUM MEROZOITE ANTIGENS IN PROTECTION FROM
CLINICAL MALARIA
Danielle I. Stanisic1, Jack Richards2, Fiona J. McCallum2, Danny
Wilson2, Pascal Michon3, Christopher L. King4, Robin Anders5, Ivo
Mueller6, James G. Beeson2
1
Walter and Eliza Hall Institute of Medical Research, Parkville,
Australia/Papua New Guinea Institute of Medical Research, Madang, Papua
New Guinea, 2Walter and Eliza Hall Institute of Medical Research, Parkville,
Australia, 3Papua New Guinea Institute of Medical Research, Madang,
Papua New Guinea, 4Centre for Global Health and Diseases, Case Western
Reserve University, Cleveland, OH, United States, 5LaTrobe University,
Bundoora, Australia, 6Papua New Guinea Institute of Medical Research,
Goroka, Papua New Guinea
552
1
548
IN UTERO HUMORAL IMMUNE RESPONSES TO P. VIVAX AND
P. FALCIPARUM ANTIGENS IN PAPUA NEW GUINEA
Danielle I. Stanisic1, James G. Beeson2, Ivo Mueller3, Stephen
Rogerson4, Christopher L. King5
1
RELATIONSHIP OF IL-18 PROMOTER POLYMORPHISM (-137
G/C) WITH SEVERE MALARIAL ANEMIA AND HYPER-PARASITEMIA IN INFANTS AND YOUNG CHILDREN
Richard Otieno1, Collins Ouma1, Tom Were1, Gordon Awandare2,
Gregory Davenport2, John Vulule3, John Michael Ong’echa1, Jeremy
Martinson2, Robert Ferrell2, Douglas Perkins2
Walter and Eliza Hall Institute of Medical Research, Parkville,
Australia/Papua New Guinea Institute of Medical Research, Madang, Papua
New Guinea, 2Walter and Eliza Hall Institute of Medical Research, Parkville,
Australia, 3Papua New Guinea Institute of Medical Research, Goroka, Papua
New Guinea, 4Department of Medicine, University of Melbourne, Parkville,
Australia, 5Centre for Global Health and Diseases, Case Western Reserve
University, Cleveland, OH, United States
1
Pittsburgh, PA, United States, 3KEMRI, Kisumu, Kenya
127
Tuesday, November 6
546
Detailed Program
www.astmh.org
553
558
WHAT WOULD EXPLAIN THE DIFFERENCES IN
SUSCEPTIBILITY OF DCS SUBSETS TO MALARIA
INFECTION DURING PREGNANCY?
STERILE PROTECTION AGAINST MALARIA INFECTION
REQUIRES TAP IN SPITE OF COMPLETELY OPERATIVE TAPINDEPENDENT VACUOLAR CROSS-PRESENTATION PATHWAY
Aliou Mamadou Diallo1, Delphine Aldebert2, Omar Thiaw1, Jean
Charle Moreau1, Ndiaye Malick3, Jambou Ronan4
Dmitry Liepinsh
University of Dakar, Dakar, Senegal, 2University Joseph Fourier of Grenoble,
Grenoble, France, 3Institut Hygiène Service, Dakar, Senegal, 4Pasteur
Institute of Dakar, Dakar, Senegal
1
(ACMCIP Abstract)
554
THE ACQUISITION AND MAINTENANCE OF
ANTIBODIES AGAINST P. FALCIPARUM MEROZOITE ANTIGENS
IN CHILDHOOD
Cleopatra K. Mugyenyi1, Kurt Lackovic2, Nimmo Gicheru1, Hellen
Gatakaa1, Gregory Fegan1, Robin Anders3, Ian Street2, Thomas
Williams1, Kevin Marsh1, James Beeson2
(ACMCIP Abstract)
559
LEVELS OF MANNOSE-BINDING LECTIN DURING PREGNANCY
COMPLICATED WITH PLASMODIUM FALCIPARUM INFECTION
IN CAMEROONIAN WOMEN
Audrey D. Thevenon1, Rose G.F Leke3, Amorsolo Suguitan1,
Josephine Fogako3, Ainong Zhou4, Diane Wallace Taylor1
1
Georgetown University, Washington, DC, United States, 2John A. Burns
School of Medicine, University of Hawaii, Honolulu, HI, United States,
3
Biotechnology Center, University of Yaounde, Yaoude, Cameroon
1
Kenya Medical Research Institute - Wellcome Trust Research Programme
CGMR-C, Kilifi, Kenya, 2Walter and Eliza Hall Institute of Medical Research,
Melbourne, Australia, 3La Trobe University, Melbourne, Australia
555
ESTROGEN AND PROGESTERONE SYNERGISTICALLY
AFFECT RESPONSES TO PLASMODIUM CHABAUDI IN
FEMALE C57BL/6 MICE
Erin N. Barth, Pamela W. Klein, Michele F. Hannah, Sabra L. Klein
States
556
TEMPORAL STABILITY OF BLOOD STAGE MALARIA IMMUNE
SURROGATES OF PROTECTION IN A MALARIA HOLOENDEMIC
AREA
Arlene E. Dent1, Kiprotich Chelimo2, Peter Sumba2, Daniel Tisch1,
Michele Spring3, Ann Moormann1, James Kazura1
Medical Research Institute, Kisumu, Kenya, 3Walter Reed Army Institute of
Research, Washington, DC, United States
560
DISTRIBUTION OF PLASMODIUM FALCIPARUM MSP1 ALLELIC
VARIANTS IN THE ARTIBONITE VALLEY OF HAITI, 2006
Berlin L. Londono, Thomas P. Eisele, Joseph Keating, Adam
Bennett, Donald J. Krogstad
(ACMCIP Abstract)
561
HUMAN INSULIN REGULATES OXIDATIVE STRESS AND AGING
IN THE MALARIA VECTOR ANOPHELES STEPHENSI
Mi-Ae Kang, Tiffany M. Mott, Erin C. Tapley, Edwin E. Lewis,
Shirley Luckhart
562
1
(ACMCIP Abstract)
557
SELENIUM LEVELS, MALARIA AND ENDEMIC BURKITTS
LYMPHOMA IN WESTERN KENYA
Peter O. Sumba1, Michael Otieno2, Dickens Kowuour1, Chelimo
Kiprotich1, Alloys S. Orago2, Paula Rosenbaum3, Ann M.
Moormann4, Rosemary Rochford3
1
Kenya Medical Research Institute, Kisumu, Kenya, 2Kenyatta University,
Nairobi, Kenya, 3SUNY Upstate Medical University, Syracuse, NY, United
States, 4Case Western Reserve University, Cleveland, OH, United States
DISRUPTION OF A PUTATIVE ABC TRANSPORTER IN
PLASMODIUM FALCIPARUM ALTERS PARASITE GROWTH AND
RESPONSES TO ANTIMALARIAL DRUGS
Dipak K. Raj
(ACMCIP Abstract)
563
DIFFERENTIAL CHANGES IN PLASMODIUM FALCIPARUM
VAR TRANSCRIPTION DURING PARASITE ADAPTATION TO
IN VITRO CULTURE
Jennifer M. Peters1, Elizabeth V. Fowler1, Darren R. Krause1, Qin
Cheng2, Michelle L. Gatton1
1
Queensland Institute of Medical Research, Herston, Australia, 2Australian
Army Malaria Institute, Brisbane, Australia
128
564
www.astmh.org
570
POPULATION STRUCTURE OF PLASMODIUM FALCIPARUM IN
THE PHILIPPINES
RECOMBINATION GENERATING HAPLOTYPE DIVERSITY IN THE
LIGAND DOMAIN OF PLASMODIUM VIVAX DUFFY-BINDING
PROTEIN
Moritoshi Iwagami1, Toshimitsu Hatabu2, Aleyla S. Escueta3, Elena
A. Villacorte3, Pilarita T. Rivera3, Toshiyuki Hayakawa4, Kazuyuki
Tanabe4, Toshihide Mitamura1, Shigeyuki Kano1
Taís N. Sousa1, Eduardo Tarazona-Santos2, Paula R. Kuser3, Luzia
H. Carvalho1, Cristiana F. Brito1
1
1
Research Institute, International Medical Center of Japan, Tokyo, Japan,
Gunma University School of Health Sciences, Gunma, Japan, 3College of
Public Health, University of the Philippines Manila, Manila, Philippines,
4
Research Institute for Microbial Diseases, Osaka University, Osaka, Japan
2
Rene Rachou Institute/Oswaldo Cruz Foundation, Belo Horizonte/MG,
Brazil, 2Federal University of Minas Gerais, Belo Horizonte/MG, Brazil,
3
Laboratory of Bioinformatics/EMBRAPA, Campinas/SP, Brazil
(ACMCIP Abstract)
565
Malaria - Vaccines
DEVELOPMENT OF A PLASMODIUM GENERIC, FALCIPARUM,
AND VIVAX SPECIFIC REA TIME PCR BASED ON 18S RRNA
Kurt E. Schaecher, Mark Fukuda
571
PLASMODIUM VIVAX TRAP: IMMUNOGENICITY AND PROTECTIVE EFFICACY IN RODENTS AND AOTUS MONKEYS
Angélica M. Castellanos
566
Universidad del Valle, Cali, Colombia
Thilan A. Wickramarachchi, Sangeeta Devi, Asif Mohmmed,
Virander S. Chauhan
International Centre for Genetic Engineering and Biotechnology,
New Delhi, India
(ACMCIP Abstract)
567
DNA VACCINE TRIALS USING 3 BLOOD STAGE ANTIGENS OF
PLASMODIUM VIVAX KOREAN ISOLATES
Eun-Hee Shin, Hyo-Jin Kim, Jo Woon Yi Lee, Jin-Ju Lee,
Jong-Yil Chai
Seoul National University College of Medicine, Seoul, Republic of Korea
(ACMCIP Abstract)
(ACMCIP Abstract)
572
A PHASE I/IIB RANDOMIZED, DOUBLE-BLIND, CONTROLLED
CLINICAL TRIAL OF THE SAFETY, IMMUNOGENICITY AND EFFICACY OF RTS,S/AS02D, A CANDIDATE MALARIA VACCINE IN
MOZAMBICAN INFANTS
John J. Aponte1, Pedro Aide2, Montse Renom1, Inacio
Mandomando2, Quique Bassat1, Jahit Sacarlal2, Maria N. Manaca2,
Sarah Lafuente1, Eusebio Macete2, Amanda Leach3, Ripley Ballou3,
Marc Lievens3, Johan Vekemans3, Marie-Claude Dubois3, MarieAnge Demotie3, Joe Cohen3, Filip Dubovsky4, Jessica Millman4,
Marla Sillman4, Pedro L. Alonso1
1
Barcelona Centre For International Health Research (CRESIB), Hospital
Clinic/IDIBAPS, University of Barcelona, Barcelona, Spain, 2Manhiça Health
Research Centre (CISM), Manhiça, Mozambique, 3GlaxoSmithKline
MD, United States
573
568
THE USE OF MICROSATELITES AND TANDEM REPEATS IN
GENETIC POPULATION ANALYSIS OF FIELD PLASMODIUM
VIVAX ISOLATES FROM BRAZILIAN ENDEMIC AREAS
Antônio M. Rezende1, Cor Jésus Fontes2, Eduardo Martín Santos3,
Cristiana Ferreira Brito1
1
Centro de Pesquisas René Rachou - FIOCRUZ, Belo Horizonte - MG, Brazil,
Universidade Federal do Mato Grosso, Cuiabá - MT, Brazil, 3Universidade
Federal de Minas Gerais, Belo Horizonte - MG, Brazil
2
(ACMCIP Abstract)
THE FREQUENCY OF SP AND CQ RESISTANCE MARKERS IN
SEVEN DISTRICTS IN ZAMBIA
Busiku Hamainza1, Moonga Hawela1, Pascalina Chanda1, Hirva
Porta2, Sungano Mharakurwa3, Cally Roper4, Nawa Sipilanyambe1
2
National Malaria Control Center, Lusaka, Zambia, London School of
Hygiene, London, United Kingdom, 3Malaria Institute In Macha, Macha,
Zambia, 4MRC, Johannesburg, South Africa
(ACMCIP Abstract)
Daming Zhu, Elizabeth M. Gebregeorgis, Holly A. McClellan,
Shuhui Huang, Louis H. Miller, Laura B. Martin
Malaria Vaccine Development Branch, National Institute of Allergy
and Infectious Diseases, National Institutes of Health, Rockville, MD,
United States
574
NOVEL SPOROZOITE ANTIGEN DISCOVERY OF PLASMODIUM
FALCIPARUM SCREENED USING HUMAN IMMUNESERA
569
1
EFFECT OF CPG ON STABILITY OF BSAM-1/ALHYDROGEL FORMULATION
Ling Jin1, Satoru Takeo1, Hideyuki Iriko2, Osamu Kaneko3,
Jetsumon Sattabongkot4, Motomi Torii5, Joao Carlos Aguiar6,
Takafumi Tsuboi1
1
Ehime University, Matsuyama, Ehime, Japan, 2Tottori University, Yonago,
Tottori, Japan, 3Nagasaki University, Nagasaki, Nagasaki, Japan, 4Armed
Forces Research Institute of the Medical Sciences, Bangkok, Thailand,
5
Ehime University, Toon, Ehime, Japan, 6Naval Medical Research Center,
Silver Spring, MD, United States
(ACMCIP Abstract)
129
Tuesday, November 6
IDENTIFICATION AND CHARACTERIZATION OF A NOVEL
ASPARAGINES RICH MEROZOITE APICAL PROTEIN THAT IS
INVOLVED IN ERYTHROCYTE BINDING AND INVASION BY THE
MEROZOITE
Detailed Program
www.astmh.org
575
580
TRANSMISSION-BLOCKING ACTIVITY OF DNA VACCINE
ENCORDING PLASMODIUM VIVAX GAMETOCYTE PROTEIN,
PVS230
E.COLI-EXPRESSED AND REFOLDED VAR2CSA DOMAINS
INDUCE ANTIBODIES AGAINST NATIVE STRUCTURAL EPITOPES
ON THE SURFACE OF CSA-BINDING PARASITES
Mayumi Tachibana1, Chiho Eitoku1, Hitoshi Otsuki1, Jetsumon
Sattabongkot2, Motomi Torii1, Takafumi Tsuboi3
Andrew V. Oleinikov, Jeffrey R. Dorfman, Eddie Rossnagle, Susan
Francis, Michal Fried, Stephanie Balcaitis, Tony Getz, Marion Avril,
Joe D. Smith, Patrick E. Duffy
1
Department of Molecular Parasitology, Ehime University Graduate School of
Medicine, Ehime, Japan, 2Department of Entomology, United States Army
Medical Component Armed Forces Research Institute of the Medical
Sciences, Bangkok, Thailand, 3Cell-Free Science and Technology Research
Center, Ehime University, Ehime, Japan
576
A PLATFORM FOR GENERATING CONJUGATED MALARIAL
VACCINES TO PSEUDOMONAS AERUGINOSA EXOPROTEIN A
Feng Qian1, Karine Reiter1, Yanling Zhang1, Richard L. Shimp, Jr.1,
Vu Nguyen1, Jacob Lebowitz2, Lynn Lambert1, Gregory E. Mullen1,
Laura B. Martin1, Louis H. Miller1, David L. Narum1
1
National Institutes of Health, Rockville, MD, United States, 2National
Institutes of Health, Bethesda, MD, United States
577
(ACMCIP Abstract)
581
DEVELOPING DNA-PRIME ADENOVIRUS-BOOST VACCINES FOR
THE PREVENTION OF MALARIA
Ilin Chuang1, David R. Regis1, Martha Sedegah1, José MendozaSilveiras1, Joseph T. Bruder2, Richter C. King2, Noelle B. Patterson1,
Keith Limbach1, Sofia Casares1, Santina Maiolatesi1, Lorraine
Soisson3, Carter Diggs3, Walter Weiss1, Denise L. Doolan1, Thomas
L. Richie1
1
Naval Medical Research Center, Silver Spring, MD, United States, 2GenVec
Inc., Gaithersburg, MD, United States, 3United States Agency for
International Development, Washington, DC, United States
P. VIVAX VACCINE: IMMUNOLOGICAL CHARACTERIZATION
OF NEW CANDIDATE VACCINE USING GENOMIC AND
PROTEOMIC DATA
Elizabeth Ampudia
Instituto de Inmunología, Cali, Colombia
(ACMCIP Abstract)
578
IMPACT OF RTS,S/AS02A AND RTS,S/AS01B ON
MULTIPLICITY OF INFECTIONS AND CSP T-CELL EPITOPES
OF P. FALCIPARUM IN ADULTS PARTICIPATING IN A MALARIA
VACCINE CLINICAL TRIAL
Samuel B. Anyona1, Carol W. Hunja1, Carolyne M. Kifude1, Mark E.
Polhemus1, D. Gray Heppner2, Amanda Leach3, Marc Lievens3,
Ripley Ballou3, Joe Cohen3, Colin Sutherland4, John N. Waitumbi1
1
Walter Reed Project, Kenya Medical Research Institute, Kisumu, Kenya,
2
Division of Malaria Vaccine Development, Walter Reed Army Institute of
Research, Silver Spring, MD, United States, 3GlaxoSmithKline Biologicals,
Rixensart, Belgium, 4London School of Hygiene and Tropical Medicine,
579
A NOVEL POPULATION GENOMIC APPROACH FOR
IDENTIFYING VACCINE TARGETS
Daniel E. Neafsey1, Danny Park1, Sarah K. Volkman2, Pardis C.
Sabeti1, Dyann F. Wirth2, James E. Galagan1
1
Broad Institute of MIT and Harvard, Cambridge, MA, United States,
2
Harvard School of Public Health, Cambridge, MA, United States
582
VECTOR COMPETENCE OF FLORIDA AEDES AEGYPTI AND AE.
ALBOPICTUS TO LA RÉUNION STRAIN (LR2006 OPY1) OF
CHIKUNGUNYA VIRUS
Michael H. Reiskind, Kendra Pesko, Catherine J. Westbrook,
Christopher N. Mores
University of Florida, Vero Beach, FL, United States
583
FIELD COMPARISON OF ANOPHELINE COLLECTION METHODS:
CO2-BAITED CDC LIGHT TRAPS VERSUS HUMAN LANDING
CATCHES IN BELIZE, CENTRAL AMERICA
Nicole L. Achee1, Isabelle Dusfour1, David Claborn1, Ireneo
Briceno2, Russell King2, John Grieco1
1
States, 2Belize Ministry of Health, Belmopan, Belize
584
MOSQUITOES IN SPACE AND TIME: METEOROLOGIC AND
EDAPHIC FACTORS AFFECTING CULEX TARSALIS ABUNDANCE
IN CALIFORNIA
Christopher M. Barker1, William K. Reisen1, Bruce F. Eldridge1,
Wesley O. Johnson2, Jeff Gill1
1
University of California, Davis, CA, United States, 2University of California,
Irvine, CA, United States
585
AUTOMATED DETECTION AND RECORDING OF MOSQUITOES
FLYING THROUGH EAVES OF AN AFRICAN VILLAGE HUT
Philipp Kirsch1, John Mclaughlin1, Darek Czokajlo1, Aubrey Moore2
1
APTIV Inc., Portland, OR, United States, 2University of Guam, Mangilao,
GU, United States
130
586
Wannapa Suwonkerd1, Nantawan Suwannachote1, Thum
Boonti1, Theeraphap Chareonviriyaphap2
1
Office of Disease Prevention and Control, Ministry of Public Health, Chiang
Mai, Thailand, 2Department of Entomology, Faculty of Agriculture, Kasetsart
University, Bang Khen, Bangkok, Thailand
587
LOGISTICS OF LARGE SCALE LARVAL ANOPHELES GAMBIAE
CONTROL: TRACKING INSECTICIDE APPLICATION WITH DIGITAL TECHNOLOGY
M. N. Bayoh1, Allen Hightower2, Maurice Ombok1, Francis
Mutuku1, Edward D. Walker3, John M. Vulule1, John E. Gimnig2
1
Kenya Medical Research Institute, Kisumu, Kenya, 2Centers for Disease
Control and Prevention, Atlanta, GA, United States, 3Michigan State
University, East Lansing, MI, United States
588
LIGHTS, CAMERA, ACTION: A METHOD TO STUDY MALE
ANOPHELES GAMBIAE MATING BEHAVIOR IN THE FIELD
Nicholas C. Manoukis1, Abdoulaye Diabate1, Adama Dao2, Fuyuki
Tokumasu1, Tovi Lehmann1
1
Health, Bethesda, MD, United States, 2MRTC/FMPOS, Bamako, Mali
589
LABORATORY OVIPOSITION RESPONSES OF AEDES AEGYPTI
TO VOLATILES FROM PLANT INFUSIONS AND CULTURED
BACTERIAL ISOLATES FROM PLANT INFUSIONS
Loganathan Ponnusamy, Coby Schal, Charles Apperson
North Carolina State University, Raleigh, NC, United States
590
IDENTIFICATION OF MOSQUITO PROTEINS INVOLVED IN THE
MOSQUITO-BORNE FLAVIVIRUS LIFECYCLE
Jonathan T. Cox1, John F. Anderson2, Erol Fikrig1
592
MEASURING THE IMPACT OF UNPREDICTABLE
ENVIRONMENTS ON MOSQUITO VECTORS AND
IMPLICATIONS FOR DISEASE RISK MODELING
Constantianus J. Koenraadt, Hong Fei Gong, Laura C. Harrington
593
IS VERTEBRATE BLOOD QUALITY CORRELATED WITH
THE HOST SPECIES SPECIALIZATION OF AFRICAN
MALARIA VECTORS?
Heather Ferguson
University of Glasgow, Glasgow, United Kingdom
594
FUTURE THREAT FROM VIVAX MALARIA IN
THE UNITED KINGDOM
Steve W. Lindsay, D.G. Hole, Rob Hutchinson, Steven G. Willis
University of Durham, Durham City, United Kingdom
595
A PREDICTIVE LANDSCAPE MODEL OF ANOPHELES GAMBIAE
LARVAL HABITATS IN LOWLAND WESTERN KENYA
Francis Mutuku1, M.N. Bayoh1, John E. Gimnig2, John M. Vulule1,
Jones M. Mueke3, Edward D. Walker4
1
Kenya Medical Research Institute, Kisumu, Kenya, 2Centers for Disease
Control and Prevention, Atlanta, GA, United States, 3Kenyatta University,
Nairobi, Kenya, 4Michigan State University, East Lansing, MI, United States
596
STUDIES ON INSECTICIDE USAGE PATTERN AND RESISTANCE
STATUS OF ANOPHELES GAMBIAE S.S IN THE ASHANTI
REGION OF GHANA
Joseph B. Stiles-Ocran1, Michael D. Wilson1, Margaret T.
Frempong2, Williams K. Owiredu2, Daniel A. Boakye1
1
Noguchi Memorial Institute for Medical Research, Legon, Accra, Ghana,
2
1
Yale University, New Haven, CT, United States, 2Connecticut Agircultural
Experiment Station, New Haven, CT, United States
591
COMPLEXITIES IN THE RECOGNITION AND DIFFERENTIATION
OF VECTORS AND NON-VECTORS OF MALARIA IN SOUTHERN
ZAMBIA
Douglas E. Norris1, E. A. Misiani2, Christen M. Fornadel1, Lizette L.
Koekemoer2, Richard H. Hunt2, Maureen Coetzee2
1
States, 2National Institute for Communicable Diseases, Johannesburg,
South Africa
597
MALARIA TRANSMISSION RISK AND IRRIGATION IN NORTHERN GHANA
Maxwell A. Appawu1, Samuel Dadzie1, Victor Asoala2, Francis
Anto2, Kwadwo Koram1, William Rogers3, David J. Fryauff4
1
Noguchi Medical Research Institute, Accra, Ghana, 2Navrongo Health
Research Center, Navrongo, Ghana, 3United States Naval Medical Research
Unit No. 3, Cairo, Egypt, 4Naval Medical Research Center, Silver Spring, MD,
United States
131
Tuesday, November 6
THE EVIDENCE OF INCREASING LEVEL ON SUSCEPTIBLE TO
PYRETHROID OF AEDES AEGYPTI IN PANG MAI DAENG
VILLAGE IN NORTHERN THAILAND
www.astmh.org
Detailed Program
www.astmh.org
598
Protozoa – Opportunistic Protozoa
VECTOR COMPETENCE OF SELECTED KENYAN MOSQUITO
(DIPTERA: CULICIDAE) SPECIES FOR RIFT VALLEY FEVER VIRUS
603
Michael J. Turell1, John S. Lee1, Jason H. Richardson2, Rosemary C.
Sang3, Elizabeth N. Kioko2, Maurice O. Agawo2, James Pecor4,
Monica L. O’Guinn1
1
United States Army Medical Research Institute for Infectious Diseases,
Frederick, MD, United States, 2US Army Medical Research Unit, Nairobi,
Kenya, 3Kenya Medical Research Institute, Nairobi, Kenya, 4Walter Reed
Army Institute of Research, Washington, DC, United States
599
TEMPORAL AND SPATIAL PATTERNS OF WEST NILE VIRUS
TRANSMISSION IN SAGINAW COUNTY, MICHIGAN, 2003-2005:
EVIDENCE FROM MOSQUITO POOLS, DEAD BIRDS, AND SENTINEL PHEASANTS SUGGEST HUMAN RISK FACTORS
Ting-Wu Chuang1, Randall G. Knepper2, William W. Stanuszek2,
Edward D. Walker3, Mark L. Wilson1
COMPARATIVE CLUSTERS OF ORTHOLOGOUS GENE ANALYSIS
OF BABESIA, PLASMODIUM AND THEILERIA
Audrey O. Lau
Washington State University, Pullman, WA, United States
604
IN VIVO EFFECTS OF PYRIMETHAMINE AND ARTESUNATE ON
ACUTE AND CHRONIC TOXOPLASMOSIS
Phuangphet Waree1, David JP Ferguson2, Emsri Pongponratn3,
Urai Chaisri3, Yaowalark Sukthana1
1
Department of Protozoology, Faculty of Tropical Medicine, Mahidol
University, Bangkok, Thailand, 2Nuffield Department of Pathology, Oxford
University, John Radcliffe Hospital, Oxford, United Kingdom, 3Department of
Tropical Pathology, Faculty of Tropical Medicine, Mahidol University,
Bangkok, Thailand
1
Department of Epidemiology, School of Public Health, University of
Michigan, Ann Arbor, MI, United States, 2Saginaw County Mosquito
Abatement Commission, Saginaw, MI, United States, 3Department of
Microbiology and Molecular Genetics, Michigan State University, Lansing,
MI, United States
600
A MODIFIED Y-TUBE OLFACTOMETER TO INVESTIGATE THE
HOST DENSITY-DEPENDENT BEHAVIORAL RESPONSE OF MOSQUITOES
605
CHARACTERISATION OF THE EFFECTS OF PENTAMIDINEDERIVATIVES IN NEOSPORA CANINUM- AND TOXOPLASMA
GONDII-INFECTED CELL CULTURES
Angela Leepin1, Angela Stuedli2, Reto Brun2, David Boykin3,
Andrew Hemphill1
1
University of Berne, Berne, Switzerland, 2Swiss Tropical Institute, Basel,
Switzerland, 3Georgia State University, Altanta, GA, United States
606
Ivo M. Foppa1, Richard G. Vogt2
1
Arnold School of Public Health, University of South Carolina, Columbia, SC,
United States, 2Department of Biological Sciences, University of South
Carolina, Columbia, SC, United States
601
MOSQUITO AND BITING MIDGE MIDGUT STRUCTURES AND
PROCESSES THAT MAY AFFECT ARBOVIRUS INFECTION AND
DISSEMINATION
William S. Romoser1, Marco Neira2, Renato Leon3, Lisa A.
Patrican4, William K. Reisen5
1
College of Osteopathic Medicine, Tropical Disease Institute, Athens, OH,
United States, 2The Whitney Laboratory, St. Augustine, FL, United States,
3
College of Health Sciences, Universidad San Francisco de Quito, Quito,
Ecuador, 4New York State Department of Health, Arthropod-Borne Disease
Program, Diagnostic Laboratory, College of Veterinary Medicine, Cornell
University, Ithaca, NY, United States, 5Arbovirus Field Station, Center for
Vector Borne Disease, University of California, Bakersfield, CA, United States
602
EFFECTS OF LANDSCAPE PATTERNS AND BIRD COMMUNITY
COMPOSITION ON WEST NILE VIRUS TRANSMISSION PATTERNS IN CT
EFFECTIVENESS OF A RIBOFLAVIN AND LIGHT BASED
PATHOGEN REDUCTION TECHNOLOGY (PRT) SYSTEM TO
ELIMINATE BABESIA MICROTI FROM APHERESIS PLATELETS
AND PLASMA
Laura Tonnetti1, Melanie C. Proctor1, Heather L. Reddy2, Raymond
P. Goodrich3, David A. Leiby1
1
American Red Cross, Rockville, MD, United States, 2Navigant
Biotechnologies, Lakewood, CO, United States, 3Navigant Biotechnology,
Lakewood, CO, United States
(ACMCIP Abstract)
607
THE PROINFLAMMATORY CYTOKINE EXPRESSIONS WERE
SUPPRESSED BY TLR2 IN MACROPHAGES TREATED WITH
TOXOPLASMA GONDII LYSATE
Myoung-Hee Ahn
Hanyang University College of Medicine, Seoul, Republic of Korea
(ACMCIP Abstract)
Maria Diuk-Wasser1, Goudarz Molaei2, Anna Milkowski1, Heidi
Brown1, Theodore Andreadis2, Durland Fish1
1
Yale University, New Haven, CT, United States, 2Connecticut Agricultural
Experiment Station, New Haven, CT, United States
132
608
IMMUNOSUPPRESSION OF MICE AFTER INTRAPERITONEAL OR
GASTRODUODENAL INJECTION WITH A VIRULENT
TOXOPLASMA GONDII KOREAN ISOLATE (KI-1)
www.astmh.org
614
MONKEYPOX: ECOLOGICAL AND LABORATORY
INVESTIGATIONS OF HOST-VIRUS DYNAMICS
Jong-Yil Chai, Hyo-Jin Kim, Jo Woon Yi Lee, Jin-Ju Lee,
Eun-Hee Shin
Darin S. Carroll, Christina L. Hutson, Joshua S. Self, Victoria A.
Olson, Mary G. Reynolds, Jason A. Abel, Russell L. Regnery,
Inger K. Damon
Seoul National University College of Medicine, Seoul, Republic of Korea
615
(ACMCIP Abstract)
609
SERUM ANTIBODY RESPONSES TO CP27, AN IMMUNODOMINANT CRYPTOSPORIDIUM SPP. ANTIGEN IN BANGLADESHI
CHILDREN WITH DIARRHEA AND CRYPTOSPORIDIOSIS
Anoli J. Borad1, Geneve Allison1, Wasif A. Khan2, Anne V. Kane1,
Kathleen Rogers1, Mohammad M. Karim2, Sabeena Ahmed2,
Patricia L. Hibberd1, Stephen B. Calderwood3, Edward T. Ryan3,
Honorine D. Ward1
1
Tufts-New England Medical Center, Boston, MA, United States,
International Centre for Diarrheal Disease Research, Dhaka, Bangladesh,
3
2
A PHYLOGENETIC ANALYSIS OF SOUTH AMERICAN EASTERN
EQUINE ENCEPHALITIS VIRUS
Nicole C. Arrigo, Douglas M. Watts, Scott C. Weaver
616
GENETIC DIVERSITY AND POSITIVE SELECTION IN EASTERN
EQUINE ENCEPHALITIS VIRUS
Orchid M. Allicock1, Albert J. Auguste1, Eleca J. Dunham2,
Oliver G. Pybus3, Edward C. Holmes2, Christine V. Carrington1
1
(ACMCIP Abstract)
University of the West Indies, St. Augustine, Trinidad and Tobago,
Pennsylvania State University, State College, PA, United States, 3University
of Oxford, Oxford, United Kingdom
610
OSTEOPROTEGERIN (OPG) PROTECTS CRYPTOSPORIDIUM
AGAINST DEATH INDUCED BY TRAIL (TNF-RELATED APOPTOSIS-INDUCING LIGAND)
Alejandro Castellanos1, Linda S. Yancey2, Heuy-Ching Wang2,
Birte Pantenburg1, Kathleen R. Liscum2, Dorothy E. Lewis2, A.
Clinton White Jr.1
1
University of Texas Medical Branch, Galveston, TX, United States, 2Baylor
College of Medicine, Houston, TX, United States
617
GENOTYPE SHIFT AND REEMERGENCE OF CHIKUNGUNYA IN
INDIA
Paban K. Dash, Manmohan Parida, S.R. Santhosh, N.K. Tripathi, A.
Srivastava, Parag Saxena, Nimesh Gupta, S.K. Verma, P.V.
Lakshmana Rao
Defence Research and Development Establishment, Gwalior, India
618
Viruses - Other
611
A ROLE FOR AMINO ACIDS
ASSEMBLY AND BUDDING
212
KLR214 OF EBOLA VIRUS VP40 IN
Sarah E. McCarthy, Reed F. Johnson, Ronald N. Harty
612
CRIMEAN-CONGO HEMORRHAGIC FEVER VIRUS ENCODES AN
NSM PROTEIN
Louis A. Altamura1, Jose Stubbs1, Connie S. Schmaljohn2, Robert
W. Doms1
1
University of Pennsylvania, Philadelphia, PA, United States, 2United States
Army Medical Research Institute for Infectious Diseases, Fort Detrick,
BIOSURETY AND REGIONAL PREPAREDNESS FOR A
POTENTIAL INFLUENZA PANDEMIC AND OTHER THREATS
POSED BY BIOLOGICAL SELECT AGENTS AND TOXINS: THE
ARMED FORCES RESEARCH INSTITUTE OF THE MEDICAL
SCIENCES EXPERIENCE
Fernando Guerena-Burgueno1, Bonnie L. Smoak1, Sorachai
Nitayapan1, James D. McLain1, Tippawan T. Na Ayuttaya1,
Duangsuda Siriyanonda1, Richard G. Jarman1, Kathleen W. Carr2,
Clifford E. Wendel3
1
3
US Army Medical Research and Materiel Command, Fort Detrick, MD,
United States
2
(ACMCIP Abstract)
613
INFECTIOUS CLONES OF CHIKUNGUNYA VIRUS (LA RÉUNION
ISOLATE) FOR VECTOR COMPETENCE STUDIES
Konstantin A. Tsetsarkin, Dana L. Vanlandingham, Charles E.
McGee, Stephen Higgs
(ACMCIP Abstract)
133
Tuesday, November 6
2
Detailed Program
www.astmh.org
619
A SEROSURVEY OF THE KENYAN SOMALI HERDER
POPULATION IN NORTHEAST PROVINCE DURING THE RIFT
VALLEY FEVER VIRUS EPIDEMIC OF 2006/07
David Schnabel1, Daniel Feikin2, Kariuki Njenga3, Allen
Hightower3, O.A. Omar4, Patrick Nguku5, Rashid Osman4, Omar
Farah6, Ahmed Mohamed7, Rob Breiman3
1
United States Army Medical Research Unit - Kenya, Nairobi, Kenya,
Centers for Disease Control and Prevention, Kisumu, Kenya, 3Centers for
Disease Control and Prevention, Nairobi, Kenya, 4Kenya Ministry of Health,
Garissa, Kenya, 5Kenya Ministry of Health, Nairobi, Kenya, 6Garissa
Provincial Hospital, Garissa, Kenya, 7Istin Subdistrict Hospital, Garissa, Kenya
2
620
REDUCING MEASLES BURDEN IN NIGERIA: LESSONS FROM
THE ANAMBRA STATE INTEGRATED MEASLES IMMUNIZATION
CAMPAIGN 2006
Amobi L. Ilika
Nnamdi Azikiwe University Teaching Hospital, Nnewi Anambra State, Nigeria
Poster Session B ACMCIP Abstracts – Molecular, Cellular
and Immunoparasitology
393, 395, 396, 417, 418, 419, 440, 466, 477, 482, 485, 488, 52,
511, 512, 513, 518, 524, 525, 526, 530, 533, 542, 545, 550, 553,
556, 558, 560, 562, 566, 567, 568, 569, 570, 571, 574, 577, 580,
66, 67, 68, 609, 613, 618
Mid-Day Session 79
Focus Group Lunch with ASTMH Education Committee:
Career Development in Tropical Medicine and Global
Health
Salon CD
Tuesday, November 6, 2007 12:15 p.m. - 1:15 p.m.
Interested in tropical medicine and/or global health but feeling frustrated or
unsure about how to make it a real career? The ASTMH education committee is hosting a focus group lunch supported by The Burroughs Wellcome
Fund. This session will encourage discussion among meeting attendees
regarding their questions and concerns around career development and professional advancement. Focus group leaders will also solicit and record
feedback on how the Society can best support the needs of its next generation of scientists, clinicians and public health leaders. Meeting attendees at
all levels of training [i.e. graduate students, medical students, postdoctoral
fellows, clinical interns, residents and fellows, new academic appointees (eg.
assistant professors, lecturers)], as well as anyone who would like to share
useful information regarding training or entry/advancement in both traditional and non-traditional career tracks in tropical medicine and global
health are welcome. Come have lunch and give us your input!
CHAIR
Stephen Higgs
Sarah Volkman
ROUNDTABLE HOSTS
Mid-Day Session 78
Noah Craft, MD, PhD, DTM&H
UCLA, Los Angeles, CA, United States
Bioinformatics Resources for Tropical Diseases: NCBI
Resource Update
Salon AB
The U.S. National Center for Biotechnology Information at the National
Institutes of Health is the U.S. national resource for molecular biology information. NCBI develops software and databases to better understand fundamental molecular and genetic processes that control health and diseases.
NCBI makes these resources including GenBank, PubMed, BLAST, etc. freely
available to the public. This session provides an update of new computational tools, including genome analysis and databases available at NCBI for
tropical disease research. More detail information is available at
http://www.ncbi.nlm.nih.gov/.
SPEAKER
Chuong Huynh
Nationa Institutes of Health, Bethesda, MD, United States
Hector Gorbea, MD
University of Puerto Rico, San Juan, PR, United States
Laura C. Harrington, PhD
Risa Hoffman, MD, MPH
UCLA, Los Angeles, CA, United States
Charles E. McGee
Victoria P. McGovern, PhD
The Burroughs Wellcome Fund, Research Triangle Park, NC, United States
Claire Panosian, MD, DTMH
Stephen Wikel, PhD
Jack Woodall, PhD
Federal University of Rio De Janeiro, Petropolis, Brazil
Peter Zimmerman, PhD
134
Mid-Day Session 79A
www.astmh.org
12:45 p.m.
COSTING OF VECTOR CONTROL
Supported with funding from GlaxoSmithKline
Salon E
Malaria is increasing to previously non-endemic regions in Africa. Epidemics
of malaria, dengue fever and cholera follow tropical storms in Central
America. West Nile virus arrives in New York City. Global warming and
resulting climatic instability appear to be driving a resurgence and spread of
infectious tropical diseases. What extra burdens will climate change impose?
CHAIR
Win Gutteridge
HEAT AND HEALTH: WILL TROPICAL DISEASES WORSEN AS
CLIMATE CHANGES?
Paul Epstein
Christian Lengeler
1 p.m.
THE IMPORTANCE OF THE HEALTH SYSTEM IN DYNAMIC
MODELING OF THE IMPACT OF MALARIA CONTROL
Marcel Tanner
Meet the Professors C: It’s the Singer, Not
the Song: How to Give an Effective Medical
and Scientific Presentation
Franklin 1
This session will explore how science, levity and personal anecdotes combine
for a dynamic and engaging presentation.
Mid-Day Session 80
CHAIR
Anne McCarthy
Simulation Modeling of the Epidemiology and Control
of Malaria
Salon IJ
Jay Keystone
Toronto Hospital, Toronto, ON, Canada
We describe a mathematical individual-based simulation model of
Plasmodium falciparum malaria in humans. The model includes infection
dynamics in humans and transmission dynamics between humans and mosquitoes for a variety of ecological settings. Adding malaria control interventions in the context of different health systems allows us to predict the costeffectiveness of these interventions.
SPEAKER
Mid-Day Session 82
Optimizing Prevention Strategies for Travelers’ Malaria –
Including Improving Diagnosis and Effective Therapy
CHAIR
Franklin 3/4
Thomas A. Smith
Malaria remains the leading life-threatening infection of travelers to endemic areas. Although there are now three effective chemoprophylactic strategies for prevention, rates of malaria in returned travelers have not decreased
in non-endemic countries such as Canada and the United States. Travelers
continue to underutilize all preventive strategies, including insect repellents
and insecticide treatment of nets and clothing. This symposium will review
evidenced based strategies for malaria prevention in travelers.
Marcel Tanner
12:15 p.m.
SIMULATION MODELING OF THE EPIDEMIOLOGY AND
CONTROL OF MALARIA (OVERVIEW)
CHAIR
Thomas A. Smith
Anne McCarthy
12:30 p.m.
12:15 p.m.
PROGRESS IN MODELING VACCINES AND VECTOR CONTROL
Nakul Chitnis
OVERVIEW OF TRAVELERS’ MALARIA: EPIDEMIOLOGY,
PREVENTION AND MANAGEMENT STRATEGIES
Anne McCarthy
135
Tuesday, November 6
The Heat Is On: The Impact of Climate Change on
Tropical Diseases
www.astmh.org
Detailed Program
12:30 p.m.
Symposium 83
WHY DON’T WE BOTHER TO PREVENT THOSE MALARIA
MOSQUITO BITES? AN EVIDENCED-BASED REVIEW OF
EFFECTIVE INSECT PREVENTION STRATEGIES FOR TRAVELERS
Molecular Mechanisms of Plasma Leakage in Viral
Hemorrhagic Fevers
Steve Schofield
Salon AB
Canadian Department of National Defence, Dunrobin, ON, Canada
12:45 p.m.
PEDIATRIC TRAVELERS’ MALARIA: PREVENTION AND
MANAGEMENT
Anne McCarthy
1 p.m.
WHEN PREVENTION FAILS: STRATEGIES FOR OPTIMIZING
DIAGNOSIS AND MANAGEMENT IN NON-ENDEMIC
COUNTRIES - PREVENTING MALARIA MISHAPS
Paul Arguin
Room 336
The symposium is designed to provide an update in the understanding of
the molecular mechanisms involved in viral hemorrhagic fevers. A state of
the art review of the regulation of vascular permeability in physiological
state will lead into discussions on pathological findings in viral hemorrhagic
fevers and new findings in the molecular mechanisms of vascular leakage in
viral hemorrhagic fevers.
CHAIR
Anon Srikiatkhachorn
2:45 p.m.
REGULATORS OF VASCULAR PERMEABILITY
Peter Baluk
University of California, San Francisco, CA, United States
3:10 p.m.
PATHOLOGY OF VIRAL HEMORRHAGIC FEVERS
Sherif Zaki
Franklin Hall B
3:30 p.m.
1:30 p.m. - 7 p.m.
THE ROLE OF VASCULAR ENDOTHELIAL GROWTH FACTOR
AND ITS RECEPTORS IN DENGUE HEMORRHAGIC FEVER
Plenary Session III: Commemorative
Fund Lecture
Anon Srikiatkhachorn
Salon GH
3:50 p.m.
MECHANISMS OF PLASMA LEAKAGE IN EBOLA VIRUS
INFECTION
The ASTMH Commemorative Fund Lecture is presented annually by an invited senior researcher resident in the tropics.
CHAIR
Thomas Geisbert
United States Army Medical Research Institute of Research, Fort Detrick,
MD, United States
MALARIA CONTROL IN AFRICA: OPPORTUNITIES AND CHALLENGES IN ACHIEVING RBM 2010 GOALS
Mosquitoes - Vector Biology - Epidemiology I
Awa Coll-Seck
Executive Secretary, Roll Back Malaria Partnership, Geneva, Switzerland
Salon CD
2:45 p.m. - 4:30 p.m.
CHAIR
Coffee Break
Clare Strode
Franklin Hall B
Megan R. Wise de Valdez
136
2:45 p.m.
www.astmh.org
4 p.m.
621
627
EVIDENCE OF METABOLIC RESISTANCE IN PYRETHROID
RESISTANT POPULATIONS OF ANOPHELES GAMBIAE FROM
BENIN, WEST AFRICA
Clare Strode1, Rousseau F. Djouaka2, Adekunle A. Bakare3, Martin
C. Akogbeto2, Janet Hemingway1
1
Liverpool School of Tropical Medicine, Liverpool, United Kingdom, 2Centre
de Recherche Entomologique de Cotonou, Cotonou, Benin, 3University of
Ibadan, Ibadan, Nigeria
IMPREGNATED NETTING SLOWS INFESTATION BY TRIATOMA
INFESTANS
Michael Z. Levy1, Victor Quispe-Machaca2, Jose Ylla-Velasquez2,
Lance A. Waller1, Jean M. Richards2, Bruno Rath2, Ampara Toledo2,
Rocio Rodriguez2, Katty Borrini2, Juan G. Cornejo del Carpio3,
Eleazar Cordova-Benzaquen2, James H. Maguire4, Robert H.
Gilman5, Caryn Bern6
1
Emory University, Philadelphia, PA, United States, 2AB Prisma, Arequipa, Peru,
Direccion Regional del Ministerio de Salad, Arequipa, Peru, 4University of
Maryland, Baltimore, MD, United States, 5Bloomberg School of Public Health,
Johns Hopkins, Baltimore, MD, United States, 6Division of Parasitic Diseases,
3
3 p.m.
623
CONTROL OF CULICINES AND ANOPHELINES USING
PYRIPROXYFEN – FIELD SCALE EVALUATIONS
4:15 p.m.
1
Rothamsted Research, Harpenden, United Kingdom, 2University of
California Davis, Davis, CA, United States, 3Naval Medical Research Center
Detachment, Lima, Peru, 4Naval Medical Research Center Detachment,
Iquitos, Peru, 5University of Arkansas, Little Rock, AR, United States
1034
EFFECT OF HURRICANE KATRINA ON CONTAINER BREEDING
AEDES MOSQUITO SPECIES IN UPTOWN NEW ORLEANS,
LOUISIANA: DISPLACEMENT IS REVERSED
Dawn Wesson, Richard Campanella, Gil Stav, Sarah Michaels
3:15 p.m.
624
Symposium 85
A PARATRANSGENIC APPROACH TO CONTROL OF VISCERAL
LEISHMANIASIS: AEROBIC GUT BACTERIAL IDENTIFICATION
FROM PHLEOTOMUS ARGENTIPUS
Amber L. Read1, Ravi Durvasula1, Ivy Hurwitz1, Bobban Subhadra1,
Mathews Scott1, Kashinath Ghosh2, Robin McKelvey1, Heidi
Hillesland1, Pradeep Das3
1
University of New Mexico, Albuquerque, NM, United States, 2Walter Reed
Army Research Institute, Washington, DC, United States, 3Rajendra
Memorial Research Institute of Medical Sciences, Patna, India
(ACMCIP Abstract)
Clinical Group I
Supported with funding from International Association for
Medical Assistance to Travelers
Salon E
This symposium will feature the Marcolongo Lecture and an update on
surveillance data from GeoSentinel.
CHAIR
3:30 p.m.
Anne McCarthy
625
A LARGE SCALE LABORATORY CAGE INVESTIGATION OF
AEDES DENSONUCLEOSIS VIRUS (AEDNV) AS A SUSTAINABLE
BIOCONTROL METHOD OF AEDES AEGYPTI MOSQUITOES
Megan R. Wise de Valdez, Erica L. Suchman, Jonathan O.
Carlson, William C. Black
VINCENZO MARCOLONGO MEMORIAL LECTURE: HUMAN
AFRICAN TRYPANOSOMIASIS: A NEGLECTED DISEASE WITH
LOW PREVALENCE, BUT HIGH IMPACT
Christian Burri
3:45 p.m.
3:45 p.m.
626
QTL MAPPING OF GENES CONTROLLING PERMETHRIN RESISTANCE IN AEDES AEGYPTI
1
2:45 p.m.
GEOSENTINEL SURVEILLANCE REPORT
David O. Freedman
1
Karla L. Saavedra-Rodriguez , Adriana E. Flores-Suarez ,
Ildefonso Fernandez-Salas1, William C. Black2
1
Laboratorio de Entomologia Medica, Facultad de Ciencias Biologicas,
Universidad Autonoma de Nuevo Leon, San Nicolas de los Garza, Nuevo
Leon, Mexico, 2Department of Microbiology, Immunology and Pathology,
137
Tuesday, November 6
Gregor J. Devine1, Amy Morrison2, David Florin3, Victor Lopez4,
Helvio Astete4, Jhon Ramirez4, Stephen Yanoviak5
Detailed Program
www.astmh.org
3:30 p.m.
629
Immunoparasitology (ACMCIP): Cellular Parasitology I
CHARACTERIZING THE HOST-INTERACTIVE SURFACE OF SCHISTOSOMES USING RECOMBINANT ANTIBODIES (SCFVS) FROM
IMMUNE FISHER RATS
Jorge A. Sepulveda Toepfer, Michelle Debatis, Patrick J. Skelly,
Charles B. Shoemaker
Salon F
2:45 p.m. - 4:30 PM
States
CHAIR
3:45 p.m.
Charles B. Shoemaker
States
630
ROLE OF THE GOLGI GDP-MAN TRANSPORTER LPG2 IN
LEISHMANIA DONOVANI VIRULENCE AND EVASION OF
MACROPHAGE MICROBICIDAL ACTIVITY
Mary E. Wilson
Upasna Gaur1, Stephen M. Beverley2, Melissa Showalter3, Rahul
Dalvi4, Mary E. Wilson5
2:45 p.m.
1067
1
ARTEMISININ DERIVATIVES ACCUMULATE WITHIN DIGESTIVE
VACUOLE-ASSOCIATED NEUTRAL LIPID BODIES IN PLASMODIUM FALCIPARUM
Departments of Internal Medicine University of Iowa, Iowa City, IA, United
States, 2Department of Medical Microbiology, Washington University, St.
Louis, MO, United States, 3Veterans Affairs Medical Centre, Iowa City, IA,
United States, 4University of Iowa, Iowa city, IA, United States, 5University of
Iowa and the Veterans Affairs Medical Center, Iowa City, IA, United States
Carmony Hartwig1, Andrew Rosenthal2, John D'Angelo2, Gary
Posner2, Roland Cooper1
4 p.m.
1
Old Dominion University, Norfolk, VA, United States, 2Johns Hopkins
University, Baltimore, MD, United States
631
KILLED BUT METABOLICALLY ACTIVE (KBMA) LEISHMANIA A NOVEL PROTOZOAN VACCINE TECHNOLOGY FOR VISCERAL
LEISHMANIASIS THAT IS ENHANCED BY TOLL-LIKE RECEPTOR
ACTIVATION
3 p.m.
1068
A LARGE RETROPOSON FAMILY IS INVOLVED IN THE
REGULATION OF GENE EXPRESSION IN THE PROTOZOAN
PARASITE LEISHMANIA
Ron A. Birnbaum, Stephanie Greger, Thu A. Tran, Jacquelyn N.
Haskell, Rupa Narayan, Pei L. Cheng, Kevin W. Bruhn, Noah Craft
Los Angeles Biomedical Research Institute, Division of Dermatology,
Harbor-UCLA Medical Center, UCLA School of Medicine, Torrance,
CA, United States
Michaela Muller, Fréderic Bringaud, Annie Rochette, Martin
Smith, Elodie Ghedin, Barbara Papadopoulou
Laval University, Quebec City, QC, United States
4:15 p.m.
632
3:15 p.m.
628
INNATE INFLAMMATORY AND PHAGOCYTIC RESPONSES TO
PLASMODIUM FALCIPARUM: LINKED PROCESSES OR MOLECULARLY DISCRETE PATHWAYS?
CLONING AND CHARACTERIZATION OF A FATTY ACID AND
RETINOL (FAR) BINDING PROTEIN FROM THE HOOKWORM
ANCYLOSTOMA CEYLANICUM
1
1
1
2
Keke C. Fairfax , Richard Bungiro , Lisa Harrison , Sohail Husain ,
Michael Cappello1
1
Department of Pediatrics and the Section Of Microbial Pathogenesis,
Yale University School of Medicine, New Haven, CT, United States,
2
Department of Pediatrics, Yale University School of Medicine, New
Haven, CT, United States
Laura Erdman, Gabriela Cosio, Samir N. Patel, Sergio Grinstein,
Kevin C. Kain
Toronto, ON, Canada
Symposium 87
Cerebral Malaria: Parasite Signaling Across Blood Brain
Barrier to Neuronal Dysfunction
Salon IJ
This symposium will cover current knowledge of human cerebral malaria
pathology as this pertains to interactions of blood brain barrier (BBB)
endothelium with the parasite leading to astroneuronal activation. Possible
factors involved in inducing the pathology will be discussed as indicated by
138
2:45 p.m.
CHAIR
PTO DISABILITY ESTIMATES: WHAT’S WRONG WITH THE CURRENT DALY ESTIMATES OF GLOBAL BURDEN OF DISEASE,
AND HOW DO WE FIX THEM?
Monique F. Stins
Charles H. King
Johns Hopkins School of Medicine, Baltimore, MD, United States
David J. Sullivan
United States
3:10 p.m.
PATHOGEN-ATTRIBUTABLE ANEMIA AND ANEMIA-RELATED
OUTCOMES IN THE CONTEXT OF POLYPARASITISM
2:45 p.m.
Susan P. Montgomery
THE PATHOLOGY OF HUMAN CEREBRAL MALARIA
Isabelle Medana
University of Oxford, Oxford, United Kingdom
3:35 p.m.
3:10 p.m.
IDENTIFYING CHILDHOOD AND ADULT NUTRITIONAL EFFECTS
OF PARASITIC INFECTIONS AND THEIR DISABILITY-RELATED
OUTCOMES
LOW NITRIC OXIDE BIOAVAILABILITY CONTRIBUTES TO
CEREBRAL MALARIA
Henri C. van der Heyde
La Jolla Infectious Disease Institute, La Jolla, CA, United States
3:45 p.m.
POST-ADHESIVE PROCESSES IN P.FALCIPARUM
CYTOADHERENCE
Alister Craig
Stephen T. McGarvey
4 p.m.
EFFECTIVE IMPLEMENTATION OF QUALITY OF LIFE MEASUREMENTS IN S. JAPONICUM-ENDEMIC AREAS OF CHINA
Juerg Utzinger
Liverpool School for Tropical Medicine, Liverpool, United Kingdom
4:10 p.m.
CONTRIBUTION OF SOLUBLE PLASMODIUM FACTORS
TO CEREBRAL MALARIA PATHOLOGY AT THE BLOOD
BRAIN BARRIER
Malaria - Chemotherapy
Monique F. Stins
2:45 p.m. - 4:30 p.m.
Symposium 88
Liberty AB
CHAIR
Wilfred Mbacham
University of Yaounde, Yaounde, Cameroon
Gauging the Disability Due to Chronic Infection in
Developing Countries: New Yardsticks of Health
Burden of Schistosomiasis
Joseph Njau
Salon KL
2:45 p.m.
Development Center, Dar Es Salaam, United Republic of Tanzania
633
This symposium will address evolving research interest in developing
research tools to better assess and quantify disability outcomes, DALYs and
Quality-of-Life (QoL) outcomes for non-lethal parasitic diseases of developing countries, using schistosomiasis as an example. Following an introductory talk to describe the rationale, three researchers who are active in the field
will describe their different approaches to the problem.
CHAIR
Charles H. King
USING A DEMOGRAPHIC SURVEILLANCE SYSTEM
TO ENHANCE DETECTION OF ADVERSE DRUG REACTIONS
TO MALARIA TREATMENT AND ASSOCIATED COSTS IN
RURAL TANZANIA
Joseph D. Njau1, Abdunoor M. Kabanywanyi1, John R.
MacArthur2, Aggrey Malila1, Aggrey Ngajilo1, Salim Abdulla1, Peter
Bloland3, S. Patrick Kachur3
1
Republic of Tanzania, 2United States Agency for International Development
Regional Development Mission for Asia, Bangkok, Thailand, 3Centers for
Disease Control and Prevention, Atlanta, GA, United States
139
Tuesday, November 6
human pathology and experimental in-vivo and in vitro data. Differentiation
will be made to effects of parasite adherence, soluble parasite factors and
responses from the host.
www.astmh.org
Detailed Program
www.astmh.org
3 p.m.
2
634
MONITORING THE EFFICACY AND SAFETY OF
ARTESUNATE+AMODIAQUINE (AS+AQ) OVER SIX YEARS
USING THE WHO IN VIVO PROTOCOL AND A SIMPLE PHARMACOVIGILANCE STUDY IN THE DISTRICT OF OUSSOUYE,
CASAMANCE, SOUTHERN SENEGAL
Philippe Brasseur1, Patrice Agnamey2, Oumar Gaye3,
Michel Vaillant4, Walter (Bob) R. Taylor5, Piero L. Olliaro6
1
Institut de Recherche pour le Développement (IRD), Dakar, Senegal,
2
Laboratoire de Parasitologie, Centre Hospitalo-Universitaire, Amiens,
France, 3Université Anta Diop, Dakar, Sierra Leone, 4Centre de Recherches
Publiques (CRP)- Santé, Luxembourg, Luxembourg, 5Oxford University
Clinical Research Unit , National Institute of Infectious and Tropical Diseases;
Bach Mai Hospital, Hanoi, Vietnam, 6World Health Organization (WHO)
Special Programme for Research and Training in Tropical Diseases (TDR),
Geneva, Switzerland
Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR),
Kumasi, Ghana, 3Agogo Prebyterian Hospital, Asante Akim North District,
Agogo, Ghana, 4Department of Child Health, School of Medical Sciences,
4 p.m.
638
EFFECTS OF PIPERAQUINE IN A MURINE MALARIA
TREATMENT MODEL
Brioni R. Moore1, Jeffrey D. Jago1, Christopher Andrzejewski1,
Kenneth F. Ilett2, Kevin T. Batty1
1
Curtin University of Technology, Perth, Australia, 2University of Western
Australia, Perth, Australia
4:15 p.m.
639
RETHINKING THE DEVELOPMENT OF ANTIMALARIAL
COMBINATIONS
3:15 p.m.
635
FIXED DOSE
ARTESUNATE/SULFAMETHOXYPYRAZINE/PYRIMETHAMINE
COMBINATION THERAPIES COMPARED TO ARTEMETHER/
LUMEFANTRINE FOR THE TREATMENT OF UNCOMPLICATED
PLASMODIUM FALCIPARUM MALARIA ACROSS AFRICA: AN
OPEN RANDOMIZED MULTI-CENTRE TRIAL
Issaka Sagara1, Stephen Rulisa2, Ishag Adam3, Wilfred Mbacham4,
Abdoulaye Djimde1, Ogobara Doumbo1
1
University of Bamako, Bamako, Mali, 2Central University Hospital of Kigali,
Kigali, Rwanda, 3University of Khartoum, Khartoum, Sudan, 4University of
Yaoundé, Yaoundé, Cameroon
Donald J. Krogstad1, Haiyan Deng1, Fawaz Mzayek1, Frank B.
Cogswell2, Simon J. Hocart1, Ousmane A. Koita3, Mitchell A.
Avery4, Stephen J. Cutler4
1
Tulane National Primate Research Ctr, Covington, LA, United States,
3
University of Bamako, Bamako, Mali, 4University of Mississippi, Oxford, MS,
United States
2
Symposium 90
Sand Fly Genomics
Liberty C
3:30 p.m.
636
AZITHROMYCIN COMBINATION THERAPY FOR THE
TREATMENT OF UNCOMPLICATED FALCIPARUM MALARIA:
PRELIMINARY RESULTS FROM AN OPEN LABEL RANDOMIZED
CONTROLLED TRIAL IN BANGLADESH
Kamala Thriemer1, Rashidul Haque2, Peter Starzengruber1, Aung
Swe Prue Marma3, Wasif Ali Khan2, Matthias Vossen1, Selim Akter2,
Mark Fukuda4, Harald Noedl1
1
Medical University of Vienna, Vienna, Austria, 2International Centre for
Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh, 3Bandarban
Sadar Hospital, Bandarban, Bangladesh, 4United States Army Medical
Component-Armed Forces Research Institute of the Medical Sciences,
Bangkok, Thailand
As important vectors of human disease, phlebotomine sand flies are of
global significance to human health, transmitting protozoan, bacterial and
viral pathogens. Completed genome sequences of these medically important vectors will foster development of novel technologies to control these
devastating diseases. Furthermore, phlebotomine sand fly research has
served as a key model for studies concerning vector/parasite/host interactions by revealing novel mechanisms defining vector competence, propelling
the field of vaccine research into promising areas and identifying novel therapeutics for human use. Although sand fly research has been somewhat
delayed in exploiting the burgeoning field of genomics as compared to
other human disease vectors, recent ongoing efforts greatly accelerated the
field of sand fly genomics. This symposium will provide an update of the
genetic tools that are available to the field of sand fly biology, and an
overview of the progress that has been made in applying these tools to biological questions.
CHAIR
3:45 p.m.
637
EFFECTIVENESS OF ARTEMETHER PLUS LUMEFANTRINE VERSUS ARTESUNATE PLUS AMODIAQUINE FOR THE TREATMENT
OF UNCOMPLICATED PLASMODIUM FALCIPARUM MALARIA
IN GHANAIAN CHILDREN
Robin Kobbe1, Philipp Klein1, Samuel Adjei2, Solomon Amemasor3,
Wibke Busch1, Ibrahim Lukeman2, Boakye Yiadom2, Martina
Bührlen3, Daniel Ansong4, Jürgen May1
Mary Ann McDowell
2:45 p.m.
GENE EXPRESSION AND MICROARRAY ANALYSIS OF
PHLEBOTOMINE SAND FLIES
Rod J. Dillon
1
Bernhard-Nocht-Institute for Tropical Medicine, Hamburg, Germany,
140
www.astmh.org
3:10 p.m.
4:05 p.m.
GENETIC VARIATION AMONG POPULATIONS OF THE
LUTZOMYIA LONGIPALPIS COMPLEX
Gregory C. Lanzaro
ALTERNATIVELY ACTIVATED MACROPHAGES INDUCED
DURING EXPERIMENTAL CYSTICERCOSIS HAVE A
SUPPRESSIVE ACTIVITY
University of California, Davis, CA, United States
Luis I. Terrazas
3:35 p.m.
Unidad de Biomedicina, Universidad Nacional Autónoma de México,
Tlalnepantla, Mexico
CHARACTERIZATION OF SAND FLY SIALOMES AND PRACTICAL
APPLICATION
Symposium 93
Shaden Kamhawi
4 p.m.
FUNCTIONAL GENOMICS OF PHLEBOTOMINE SAND FLIES
Marcelo Ortigao
Symposium 92
The Roles of Regulatory and Alternatively Activated
Macrophages in Helminth Infection
Franklin 3/4
The roles regulatory and alternatively activated macrophages play in helminth
infection will be discussed. This will include how these macrophages down
regulate pro-inflammatory responses in vivo, including suppression of T cell
function. How these macrophages are activated and their interactions with
other regulatory cell populations will also be discussed.
Reinfection vs. Recrudescence in P. Falciparum Malaria:
From Molecular Analysis to Clinical Impact
Salon AB
Tuesday, November 6, 2007 5 p.m. - 6:45 p.m.
In malaria endemic areas, people are often infected and re-infected with
malaria several times during a transmission season. Re-infection and parasite
recrudescence is a critical area of concern for healthcare workers, clinicians
and malaria research scientists. How do we best use genotyping to distinguish recrudescent from new infections when evaluating the clinical efficacy
of antimalarials? Can knowing the pharmacokinetics and pharmacodynamics of drugs give us insights into profiling drugs that will best counter more
clinical episodes? Correctly identifying the dynamics between re-infection
and recrudescence, and methods to stop them, can have a major public
health impact.
CHAIR
Anna Wang
Solomon Nwaka
CHAIR
Donald Harn
5 p.m.
Harvard University, Boston, MA, United States
STRATEGIES ON THE USE OF MOLECULAR TOOLS, METHODS
AND PROCEDURES IN CLINICAL TRIALS OF NEW DRUGS
William C. Gause
Hans-Peter Beck
2:45 p.m.
5:25 p.m.
MACROPHAGES AS REGULATORS AND HEALERS DURING TISSUE NEMATODE INFECTION
Judith Allen
USING PHARMACOKINETICS AND PHARMACODYNAMICS TO
PROFILE ANTIMALARIALS’ ABILITY TO COUNTER RE-INFECTION OR RECRUDESCENCE
University of Edinburgh, Edinburgh, United Kingdom
Nick J. White
3:15 p.m.
SCHISTOSOME MACROPHAGES AND COLON INFLAMMATION:
AN ALTERNATIVE VIEWPOINT
Padraic G. Fallon
Trinity Dublin College, Dublin, Ireland
5:50 p.m.
DISTINGUISHING RE-INFECTION FROM RECRUDESCENCE
IN FALCIPARUM CLINICAL TRIALS: A PUBLIC HEALTH
PROSPECTIVE
Abdoulaye A. Djimde
3:40 p.m.
THE ROLE OF ALTERNATIVELY ACTIVATED MACROPHAGES IN
PARASITIC DISEASES
Frank Brombacher
University of Cape Town, Cape Town, South Africa
141
Tuesday, November 6
Detailed Program
www.astmh.org
6:15 p.m.
6 p.m.
THE USE OF GENOTYPING TO DISTINGUISH RECRUDESCENT
FROM NEW INFECTIONS
Grant Dorsey
644
AN EVIDENCE-BASED STRATEGY TO MITIGATE NEW WATER
SUPPLY INFRASTRUCTURE RELATED DENGUE RISK IN RURAL
AREAS IN SOUTHERN VIETNAM
Jason A. Jeffery1, Peter A. Ryan1, Nguyen T. Yen2, Hoang M. Duc2,
Nguyen P. Le Anh2, Nguyen Hoang Le2, Vu S. Nam3, Tran P. Hau4,
Simon Kutcher5, Brian H. Kay1
Mosquitoes - Vector Biology - Epidemiology II
Salon CD
5 p.m. - 6:45 PM
1
Queensland Institute of Medical Research and the Australian Centre for
International and Tropical Health, Brisbane, Australia, 2National Institute of
Hygiene and Epidemiology, Hanoi, Vietnam, 3Vietnam Administration of
Preventive Medicine, Hanoi, Vietnam, 4Pasteur Institute, Ho Chi Minh City,
Vietnam, 5Australian Foundation for the Peoples of Asia and the Pacific Ltd.,
Ho Chi Minh City, Vietnam
CHAIR
6:15 p.m.
Zach N. Adelman
Virginia Technical University, Blacksburg, VA, United States
Scott A. Bernhardt
5 p.m.
640
DISSECTING THE AEDES AEGYPTI ANTI-DENGUE IMMUNE
RESPONSE
Jose L. Ramirez, Zhiyong Xi, George Dimopoulos
5:15 p.m.
641
QTL MAPPING OF RNAI GENES POSSIBLY RELATED TO
DENGUE-2 VIRUS DISSEMINATION IN THE MOSQUITO
AEDES AEGYPTI
645
SUSTAINED IMPACT OF EVIDENCE-BASED COMMUNITYDERIVED COMMUNICATION STRATEGIES FOR THE CONTROL
OF THE DENGUE VIRUS VECTOR AEDES AEGYPTI IN
MANAGUA, NICARAGUA
Jorge Arostegui1, Harold Suazo1, Alvaro Carcamo1, Carlos
Hernandez1, Josefina Coloma2, Angel Balmaseda3, Neil Andersson4,
CIETNicaragua Dengue Group1
1
CIETNicaragua, Managua, Nicaragua, 2Division of Infectious Diseases,
United States, 3Departamento de Virologia, Centro Nacional de Diagnostico
y Referencia, Ministerio de Salud, Managua, Nicaragua, 4CIETinternational,
Ottawa, ON, Canada
6:30 p.m.
646
Scott A. Bernhardt, Carol D. Blair, Barry J. Beaty, Ken E. Olson,
William C. Black
CULEX PIPIENS AMPLIFIES WEST NILE VIRUS IN NORTHEASTERN UNITED STATES BY VERTICAL AND HORIZONTAL TRANSMISSION
John F. Anderson1, Andy J. Main2, Karine Delroux3, Erol Fikrig3
1
5:30 p.m.
642
The Connecticut Agricultural Experiment Station, New Haven, CT, United
States, 2American University in Cairo, Cairo, Egypt, 3Yale University, New
Haven, CT, United States
NEGATIVE EFFECTS OF HOST SEROCONVERSION ON
MOSQUITO FITNESS
Symposium 95
Donald E. Champagne, Ryan P. Brown
Clinical Group II
5:45 p.m.
Salon E
643
A TRANSGENIC “SENSOR” STRAIN OF AEDES AEGYPTI
FOR IMPLICATING GENES INVOLVED IN THE ANTI-VIRAL
RNAI PATHWAY
Zach N. Adelman, Michelle Anderson, Elaine Morazzani,
Tiffany Gross, Nicole Plakson, Kevin M. Myles
This symposium will include a malaria update on diagnosis, treatment and
prevention, a Centers for Disease Control and Prevention vaccine update, as
well as the Clinical Group annual business meeting.
CHAIR
Anne McCarthy
Virginia Tech, Blacksburg, VA, United States
142
5 p.m.
www.astmh.org
5:15 p.m.
MALARIA DIAGNOSIS AND TREATMENT UPDATE FROM THE
WALTER REED ARMY INSTITUTE OF RESEARCH
Alan Magill
1070
ELONGATION FACTOR 1A MEDIATES THE SPECIFICITY OF
MITOCHONDRIAL TRNA IMPORT IN T. BRUCEI
Peter Weina
Eric Aeby, Nabile Bouzaidi-Tiali, Fabien Charriere, Mascha Pusnik,
Andre Schneider
University of Fribourg, Fribourg, Switzerland
5:25 p.m.
5:30 p.m.
MALARIA PREVENTION UPDATE FROM THE CENTERS FOR
DISEASE CONTROL AND PREVENTION
Paul Arguin
5:50 p.m.
647
PROTEIN TRAFFICKING TO THE MEMBRANES OF THE RELICT
CHLOROPLAST OF APICOMPLEXANS
Marilyn Parsons1, Anuradha Karnataki1, Amy DeRocher1, Isabelle
Coppens2, Jean E. Feagin1
1
CENTERS FOR DISEASE CONTROL AND PREVENTION
TRAVELERS’ VACCINE UPDATE
Seattle Biomedical Research Institute, Seattle, WA, United States, 2Johns
Hopkins University, Baltimore, MD, United States
5:45 p.m.
648
Anne McCarthy
HUMAN DEFENSIN α-1 KILLS TRYPANOSOMA CRUZI VIA
MEMBRANE PORE FORMATION LEADING TO APOPTOSIS
M. Nia Madison, Yuliya Kleshchenko, Pius Nde, Kaneatra
Simmons, Maria F. Lima, Fernando Villalta
6:15 p.m.
CLINICAL GROUP ANNUAL BUSINESS MEETING
6 p.m.
649
Immunoparasitology (ACMCIP): Cellular Parasitology II
MOLECULAR CHARACTERIZATION OF A PLASMODIUMDERIVED INFLAMMATORY FACTOR
Jamie M. Orengo1, James E. Evans2, Aleksandra Leliwa-Sytek1,
Karen P. Day1, Ana Rodriguez1
Salon F
1
5 p.m. - 6:45 PM
New York University School of Medicine, New York, NY, United States,
2
CHAIR
6:15 p.m.
Jean Feagin
ACMCIP ANNUAL BUSINESS MEETING
Sarah Volkman
Ana Rodriguez
New York Unversity, New York, NY, United States
5 p.m.
1069
A TOXOPLASMA GONDII HOMOLOGUE OF TIC20 (TGTIC20) IS
ESSENTIAL FOR APICOPLAST PROTEIN IMPORT, APICOPLAST
BIOGENESIS AND PARASITE SURVIVAL
Giel van Dooren1, Cveta Tomova2, Swati Agrawal3, Bruno
Humbel2, Boris Stripen1
1
Athens, GA, United States, 2Department of Biology, Utrecht University,
Utrecht, The Netherlands, 3Department of Cellular Biology, University of
Georgia, Athens, GA, United States
143
Tuesday, November 6
Nina Marano
www.astmh.org
Detailed Program
Symposium 97
6:10 p.m.
Recent Clinical Trials of Apical Membrane Antigen 1, a
Leading Blood-Stage Vaccine Candidate for
Plasmodium Falciparum Malaria
RANDOMIZED, CONTROLLED, PHASE 2 STUDY OF THE SAFETY
AND IMMUNOGENICITY OF AMA1-C1/ALHYDROGEL VACCINE
FOR PLASMODIUM FALCIPARUM MALARIA IN CHILDREN IN
BANCOUMANA, MALI
Salon G
Alassane Dicko
This symposium will update results from four recent phase 1 and 2 clinical
trials of apical membrane antigen 1 (AMA1) in various populations with different adjuvant formulations.
6:30 p.m.
CHAIR
Mark A. Pierce
CLOSING REMARKS AND PANEL DISCUSSION/QUESTIONS
Mark Pierce
Symposium 98
Ogobara Doumbo
5 p.m.
INTRODUCTION
Ogobara Doumbo
5:10 p.m.
ASSESSMENT OF THE SAFETY AND IMMUNOGENICITY OF THE
RECOMBINANT PICHIA PASTORIS AMA1 [PFAMA-1-FVO[25545] BLOOD STAGE MALARIA VACCINE FORMULATED IN
THREE DIFFERENT ADJUVANTS IN HEALTHY DUTCH ADULTS
Experimental Aspects of the Host-Parasite Relationship
in Cystic and Alveolar Echinococcosis
Salon H
This symposium will cover the more recent experimental insights into the
host-parasite interactions during infection with Echinococcus granulosus and
Echinococcus multilocularis. This includes (i) the taxonomy and phylogeny of
the genus Echinococcus, and aspects concerning transmission of the parasite; (ii) the host-parasite interplay during experimental E. multilocularis
infection in mice; (iii) recent insights into the pattern and significance of the
Echinococcus AgB genetic diversity; and (iv) studies on how the complex
cytokine network is modulating the immune response in experimental E.
granulosus infections.
Meta Roestenberg
Radboud University Medical Center, Nijmegen, The Netherlands
CHAIR
Andrew Hemphill
5:30 p.m.
RANDOMIZED, CONTROLLED, DOSE ESCALATION PHASE 1
CLINICAL TRIAL TO EVALUATE THE SAFETY AND
IMMUNOGENICITY OF WALTER REED ARMY INSTITUTE OF
RESEARCH‘S AMA-1 MALARIA VACCINE (FMP 2.1)
ADJUVANTED IN GSKBIO’S AS02A VS. RABIES VACCINE IN 1-6
YEAR OLD CHILDREN IN BANDIAGARA, MALI
5 p.m.
INTRODUCTION
Peter Kern
University Hospital and Medical Center, University of Ulm, Ulm, Germany
Mahamadou A. Thera
5:10 p.m.
THE TAXONOMY, PHYLOGENY AND TRANSMISSION
OF ECHINOCOCCUS
5:50 p.m.
PHASE 1/2A STUDY OF THE SAFETY, IMMUNOGENICITY AND
PRELIMINARY EFFICACY AFTER SPOROZOITE CHALLENGE OF
CANDIDATE MALARIA VACCINE AMA1 ADJUVANTED WITH
AS01B AND AS02A AND GIVEN IM AT MONTHS 0, 1, AND 2 IN
HEALTHY MALARIA-NAIVE ADULTS IN THE UNITED STATES
Michele D. Spring
Andrew Thompson
University of Murdoch, Murdoch, Australia
5:35 p.m.
HOST-PARASITE INTERPLAY IN MURINE ALVEOLAR
ECHINOCOCCOSIS
Bruno Gottstein
6 p.m.
PATTERN AND SIGNIFICANCE OF THE ECHINOCOCCUS AGB
GENETIC DIVERSITY
Karen Haag
Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
144
COMPLEXITY AND FUNCTION OF CYTOKINE RESPONSES IN
EXPERIMENTAL INFECTION BY ECHINOCOCCOSIS
Symposium 100
Sylvia Dematteis
Bridging the Access Gap: Countries Prepare to Ensure
Prompt Access to New Antimalarials
Universidad de la República, Montevideo, Uruguay
Salon KL
Symposium 99
Unmasking the Link Between Helminth Parasites and
Increased Susceptibility to Unrelated Pathogens
Salon IJ
The “hygiene hypothesis” has raised attention concerning the immunomodulatory effects of helminth parasites, including their ability to increase susceptibility to unrelated pathogens. This symposium is designed to provide a
review, as well as to update the latest progress in human studies and experimental models concerning the cellular and molecular mechanisms used by
helminth parasites to modulate host immune responses and increase susceptibility to other major tropical diseases.
CHAIR
Mary M. Stevenson
McGill University Health Centre, Montreal, QC, Canada
Artemisinin Combination Therapy (ACT) deployment today is primarily
through the public sector, whose reach is limited in many countries.
Measures are urgently needed to ensure that patients promptly receive the
new medicines for malaria. Speakers will discuss the gaps in ACT availability,
lessons learned through early deployment in Zambia and present initiatives
to widen the reach of ACTs, for example through the private sector in
Uganda. The final speaker will address issues related to managing the
opportunities and challenges that will arise in the next two years, with the
emergence of new antimalarials from the drug development process.
CHAIR
Richard W. Steketee
Malaria Control and Evaluation Partnership in Africa, Ferney Voltaire, France
5 p.m.
SETTING THE STAGE
Padmini Salgame
Richard W. Steketee
Malaria Control and Evaluation Partnership in Africa, Ferney Voltaire, France
5 p.m.
REGULATION AND FUNCTION OF ALTERNATIVELY-ACTIVATED
MACROPHAGES DURING INFECTION
Thomas A. Wynn
National Institutes of Health, Bethesda, United States
5:25 p.m.
MYCOBACTERIAL/FILARIAL CO-INFECTIONS: FROM THE FIELD
TO THE BENCH AND BACK AGAIN.
Thomas B. Nutman
5:50 p.m.
THE FILARIAL NEMATODE SECRETED PRODUCT ES-62: EFFECT
ON AUTOIMMUNITY, ALLERGY AND INFECTION WITH
PATHOGENS
William Harnett
Strathclyde University, Glasgow, United Kingdom
5:05 p.m.
BARRIERS TO PROMPT AND EFFECTIVE MALARIA TREATMENT:
WHAT MATTERS!
Christian Lengeler
5:20 p.m.
BEYOND THE PUBLIC SECTOR: LESSONS LEARNT THROUGH
EARLY DEPLOYMENT IN ZAMBIA
Elizabeth Chizema
Ministry of Health, Lusaka, Zambia
5:35 p.m.
PULLING IN THE PRIVATE INFORMAL SECTOR IN UGANDA
Ambrose Talisuna
5:50 p.m.
SCIENCE IN THE FACE OF ACCESS
6:15 p.m.
NEMATODE CO-INFECTION INFLUENCES HOST RESPONSE TO
M. TUBERCULOSIS
Padmini Salgame
145
Tuesday, November 6
6:25 p.m.
www.astmh.org
Detailed Program
www.astmh.org
5:30 p.m.
652
Malaria - Drug Development
Liberty AB
5 p.m. - 6:45 PM
CHAIR
Mary Lynn Baniecki
Alfred Tiono
CNRFP, Ouagadougou, Burkina Faso
A MULTI-DIMENSIONAL SCREENING STRATEGY TO DISCOVER
NEW ANTIMALARIAL THERAPEUTICS
Mary Lynn Baniecki1, Margaret A. Rush2, Vishal Patel1, Ralph
Mazitschek3, Robert Barker4, Roger Wiegand3, Jeff Klinger4, Dyann
F. Wirth2, Jon Clardy1
1
Harvard Medical School, Boston, MA, United States, 2Harvard School of
Public Health, Boston, MA, United States, 3The Broad Institute of Harvard
and MIT, Cambridge, MA, United States, 4Genzyme, Waltham, MA,
United States
5:45 p.m.
653
5 p.m.
650
REVIEW OF EXPERIMENTAL THERAPEUTICS CHEMICAL
INFORMATION SYSTEM FOR ALL COMPOUNDS ACTIVE IN
PROPHYLAXIS ANIMAL MODELS
Colin Ohrt1, Lahna Jones2, John Notsch1, Jacob Johnson1, William
McCalmont1, Charlotte Lanteri1, AJ Lin1, Wilbur Milhous1, Alan
Magill1, William Ellis1
1
Thermo Fisher Scientific, Inc, Gaithersburg, MD, United States
2
5:15 p.m.
651
REAL TIME ELECTRONIC DATA CAPTURE (EDC) IN PHASE III
CDA TRIALS OPTIMISES SAFETY MONITORING CHECKS AND
TRIAL CONDUCT
Alfred Tiono1, Alassane Dicko2, Zul Premji3, Tsiri Agbenyega4, Jacob
O. Awobusuyi5, Steffen Borrmann6, Fabian Essamia7, Emmanuel
Ezedinachi8, Robert Guiguemde9, Achille Massougbodji10, Dennis
Ndububa11, Stephen Oguche12, Louis Penali13, Simon Pitmang14,
Seth Owusu-Agyei15, Akin Sowunmi16, Rich Umeh16, Ismaila
Watila17, Anthony Thompson18, Lisa Nash18, Li Ean Goh18
1
CNRFP, Ouagadougou, Burkina Faso, 2MRTC, University of Bamako,
Bamako, Mali, 3Ifakara Health Research Centre, Bagamoyo District Hospital,
Dar-es-Salaam, United Republic of Tanzania, 4Komfo Anokye Teaching
Hospital, Kumasi, Ghana, 5Lagos State University Teaching Hospital, Lagos,
Nigeria, 6Kenya Medical Research Centre, Kilifi, Kenya, 7Moi University,
Eldoret, Kenya, 8University of Calabar Teaching Hospital, Delta State,
Nigeria, 9Institute Superieur des Sciences de la Sante, Universite
Polytechnique de Bobo, Diolasso, Burkina Faso, 10Faculte des Sciences de la
Sante, CNHU, Cotonou, Benin, 11Obafemi Awlowo Teaching Hospital, Ile-Ife,
Nigeria, 12University of Jos Teaching Hospital, Jos, Nigeria, 13Institute Pasteur
de Cote d’Ivoire, Abidjan, Cote d’Ivoire, 14Plateau State Specialist Hospital,
Jos, Nigeria, 15Kintampo Health Research Centre, Kintampo, Ghana,
16
University of Nigeria Teaching Hospital, Enugu, Nigeria, 17Borno State
Specialist Hospital, Maiduguri, Nigeria, 18GlaxoSmithKline, Middlesex,
United Kingdom
MALARIA-INFECTED MICE ARE CURED BY NEW TRIOXANE
DIMERS
Gary H. Posner1, Wonsuk Chang2, Andrew S. Rosenthal2,
Ik-Hyeon Paik2, Kristina Borstnik2, Sandra Sinishtaj2, Aimee Usera2,
Lindsey Hess2, Lauren Woodard2, Kimberly S. Petersen2, Theresa A.
Shapiro3
1
Department of Chemistry and Malaria Research Institute, Johns Hopkins
University, Baltimore, MD, United States, 2Department of Chemistry, Johns
Hopkins University, Baltimore, MD, United States, 3Department of Clinical
Pharmacology and Malaria Research Institute, Johns Hopkins University,
Baltimore, MD, United States
6 p.m.
654
ANTIMALARIAL ACTIVITY AND MECHANISM OF ACTION OF
ARTEMISININ ANTIMALARIALS: IS THE DIGESTIVE VACUOLE
(DV) THE PRIMARY TARGET?
Maria del Pilar Crespo Ortiz1, Thomas Avery2, Eric Hanssen3,
Dennis Taylor2, Leann Tilley1
1
Department of Biochemistry, La Trobe University, Melbourne, Australia,
Department of Chemistry, Adelaide University, South Australia, Australia,
3
Centre of Excellence for Coherent X-Ray Science, La Trobe University,
Melbourne, Australia
2
6:15 p.m.
655
TOWARD OPTIMIZATION OF ‘REVERSED CHLOROQUINES’:
IMPROVEMENTS AND NEW SCAFFOLDS
David H. Peyton, Steven J. Burgess, Jane X. Kelly, Bornface
Gunsaru, Cheryl Hodson, Katherine Liebman
Portland State University, Portland, OR, United States
146
6:30 p.m.
www.astmh.org
6:15 p.m.
656
SELECTIVE INHIBITORS OF BETA-KETOACYL ACP
SYNTHASE III (PFKASIII) IN PLASMODIUM FALCIPARUM
FATTY ACID SYNTHESIS: FROM TARGET VALIDATION TO
IN VIVO EFFICACY
Norman C. Waters1, Heather W. Gaona1, Jacob D. Johnson1,
Thomas H. Hudson1, Jayendra B. Bhonsle1, Donald P. Huddler1,
Tiffany N. Heady1, Mara Kreishman-Deitrick1, William F.
McCalmont1, Apurba K. Bhattacharjee1, Sean T. Prigge2, Norma E.
Roncal1, Miriam Lopez-Sanchez1, Lucia Gerena1, Patricia J. Lee1
1
JE CONTROL: CREATING A PUBLIC HEALTH SUCCESS
Julie Jacobson
Poster Session B Dismantle
Franklin Hall B
Tuesday, November 6, 2007 7 p.m. - 8 p.m.
2
Socio-Political Issues in Tropical Medicine: Japanese
Encephalitis Vaccines
Salon CD
Franklin 3/4
The American Committee of Molecular, Cellular and Immunoparasitology
will host the first of an annual “Meet the Professors” style session at the
ASTMH meeting on topics concerning professional development. The first of
these topics will be on mentoring, where three-four senior faculty who have
mentored many students and postdoctoral fellows will each provide 15 minutes of “mentoring pearls” from their own experiences. One or more of
these faculty members will have experience mentoring clinicians in parasitology. After the panel members share their insights, there will be an open discussion to answer questions from the audience and explore thematic topics
raised in the presentations. This session will be generally directed at senior
postdoctoral fellows, clinical fellows and junior faculty who are transitioning
to leadership roles that involve mentoring students and trainees in parasitology. A light dinner will be served.
ASTMH members are often vexed by the inability to bring basic science and
proven interventions to affected populations. Japanese Encephalitis is an
example of an emerging and a marginalized disease. It is also one of the
few tropical diseases for which there is an effective intervention (vaccines).
However, bringing JE vaccines from the lab to the field has been unnecessarily slow for a number of reasons that include but are not limited to medical/scientific debate. This symposium presents key issues from scientific,
medical and policy debates that address the role and function of JE policy
committees, how committees construct issues, evaluate evidence and how
these issues were addressed among various constituents to get the SA 1414-2 vaccine in use in South Asia.
Tuesday, November 6, 2007 7:15 p.m. - 9 p.m.
CHAIR
CHAIR
Sarah Volkman
Frank Mannix
PANELISTS
Stephen L. Hoffman
5 p.m.
Sanaria Inc., Rockville, MD, United States
AN ECOLOGICAL APPROACH TO JAPANESE ENCEPHALITIS
AND JE VACCINES
William A. Petri
Frank Mannix
5:25 p.m.
Regina Rabinovich
Dyann Wirth
VACCINE POLICY AND RECOMMENDATIONS IN ASIA
Theodore Tsai
Novartis, Philadelphia, PA, United States
5:50 p.m.
JE VACCINES: WHERE WAS THE PUBLIC INTEREST?
Scott B. Halstead
Pediatric Dengue Vaccine Initiative, IVI, Seoul, Republic of Korea
147
Tuesday, November 6
Symposium 102
Meet the Professors D: American Committee of
Molecular, Cellular and Immunoparasitology (ACMCIP):
Professional Development Series on Mentoring
www.astmh.org
Detailed Program
Symposium 104
Malaria Postgenomics
Room 305
Wednesday, November 7, 2007 7 a.m. - 8 a.m.
Salon E
Room 362
CHAIR
Press Room
This informal session will highlight postgenomic work in plasmodium. There
will be updates from major projects, as well as highlights featuring work
from the bench, clinic and field that exploits genomic and postgenomic
resources now available. Time will be available for discussion and audience
questions.
Rooms 403-404
Wednesday, November 7, 2007 8 a.m. - 6 p.m.
Symposium 105
Session 104A
Accounting for Heterogeneity Will Improve Prevention
of Mosquito-Borne Disease
Chagas: A Hidden Affliction
Salon AB
Salon H
Wednesday, November 7, 2007 8 a.m. - 9:45 a.m.
Filmed in Argentina, the United States and Europe, this documentary gives a
voice to those suffering from Chagas, and to those working to find a cure
to this disease that affects about 20 million people worldwide, but is practically unknown to the general public.
Chair
Rick L. Tarleton
PRODUCER
Ricardo Preve
Ricardo Preve Films LLC, Buenos Aires, Argentina
Recent analyses of large data sets across a variety of diseases indicate that
targeted disease prevention is more effective than uniform application
across an affected population. In this symposium, we will discuss for malaria
and dengue the impact of heterogeneities on transmission dynamics and
improved disease prevention when control is appropriately targeted.
Symposium participants are engaged in longitudinal field studies that capture person/location-specific data necessary to identify heterogeneity in
pathogen transmission for the purposes of disease prevention, developing
the theory and analytical methods necessary for effective identification of
key components of variation and developing the most effective applications
of targeted disease prevention strategies. Speakers will summarize these
data and discuss the relevance of targeting as a way of improving public
health interventions through integrated disease control, including future
field studies that combine vector control, drugs and vaccines.
CHAIR
Thomas W. Scott
Registration
David L. Smith
Fogarty International Center, Bethesda, MD, United States
8 a.m.
Cyber Cafe
FORGOTTEN LESSONS IN VECTOR-BORNE DISEASE
PREVENTION
Franklin Hall Foyer
Speaker Ready Room
Rooms 413-415
F. Ellis McKenzie
8:30 a.m.
PREVENTING CHILDHOOD MALARIA IN AFRICA BY
PROTECTING ADULTS FROM MOSQUITOES WITH INSECTICIDETREATED NETS
Gerry F. Killeen
Ifakara Health Research and Development Center, Ifakara, Kilombero
District, United Republic of Tanzania
Rooms 303-304
148
www.astmh.org
8:55 a.m.
9:20 a.m.
IMPROVING DISEASE PREVENTION WHEN HUMAN BITING
RATES ARE HETEROGENEOUS
CLINICAL TRIALS AND MALARIA CONTROL BY ARTEMISININBASED COMBINATION THERAPIES
David L. Smith
Jianping Song
Guangzhou University of Chinese Medicine, Guangzhou, China
THE VALUE OF LOCAL AND FOCAL CONTROL FOR DENGUE
Thomas W. Scott
Symposium 106
A Legacy of Antimalarial Discovery: Project 523 and the
Isolation of Artemisinin
Salon CD
Although herbal remedies from the Qinghao plant Artemisia annua were
recorded for medical ailments, including hemorrhoids, in the 2nd century
BCE, the first known clear description of malaria treatment with Qinghao
infusion was in the 4th century CE by Ge Hong, a Dao philosopher and
writer of the Jin Dynasty. When Chinese research Project 523 was launched
in 1967 to find new drugs for chloroquine-resistant malaria, its scientists
drew on Chinese traditional medicine and Ge Hong’s work to isolate
artemisinin (early 1970s). Speakers in this symposium will relate the history
of Project 523, its discovery of artemisinin and many other antimalarials,
and some subsequent clinical trials and malaria control projects with
artemisinin-based combination therapies.
CHAIR
Thomas E. Wellems
Guoqiao Li
Symposium 107
Reviving “One Medicine/One Health” Concept: To
Enhance Biomedical Research and Public Health Efficacy
Salon E
This symposium explores the rationale for a new Initiative (named the ‘One
Health’ or ‘One Medicine’ Initiative) that establishes closer ties and interactions between the human and veterinary medicine disciplines as a means to
enhance research, surveillance, treatment, prevention and control of diseases affecting humans and animals.
CHAIR
Thomas P. Monath
Kleiner Perkins Caufield & Byers, Harvard, MA, United States
Arthur H. Rubenstein
Duane Gubler
Asia-Pacific Institute of Tropical Medicine and Infectious Disease, Honolulu,
HI, United States
8 a.m.
ONE MEDICINE - POTENTIAL BENEFITS TO BIOSECURITY,
DISEASE CONTROL AND THE DEVELOPMENT OF
BIOPHARMACEUTICAL PRODUCTS
Thomas P. Monath
Kleiner Perkins Caufield & Byers, Harvard, MA, United States
8 a.m.
8:15 a.m.
GE HONG AND HERBAL MEDICINE TREATMENT FOR MALARIA
ONE MEDICINE - VETERINARY MEDICINE AND PUBLIC HEALTH
AT CENTERS FOR DISEASE CONTROL AND PREVENTION
Xinhua Wang
Lonnie J. King
8:30 a.m.
8:30 a.m.
PROJECT 523 AND THE DISCOVERY OF ARTEMISININ
ONE MEDICINE - A BRIEF HISTORICAL OVERVIEW
Keith Arnold
Laura H. Kahn
Consultant, Retired from Centre for Tropical Diseases - Ho Chi Minh City,
Lakeport, CA, United States
Princeton University, Princeton, NJ, United States
8:55 a.m.
PROJECT 523 AND ARTEMISININ DERIVATIVES
Richard K. Haynes
Hong Kong University of Science and Technology, Hong Kong
8:50 a.m.
ONE WORLD, ONE HEALTH, ONE MEDICINE - ENCHANCING
THE INTEGRATION OF ANIMAL, HUMAN AND ECOSYSTEM
HEALTH FOR THE MUTUAL BENEFIT OF ALL
Roger K. Mahr
American Veterinary Medical Association, Schaumburg, IL, United States
149
9:20 a.m.
Detailed Program
www.astmh.org
9:10 a.m.
8:45 a.m.
ONE MEDICINE - VETERINARIANS AND PHYSICIANS: THE
NEED TO COMMIT TO PREVENTION OF ZOONOTIC
PROCESSES-A PUBLIC HEALTH
H. Fred Troutt
University of Illinois, Urbana, IL, United States
9:30 a.m.
A CENTURY OF ONE MEDICINE - INTEGRATED HEALTH AND
BIOMEDICAL RESEARCH TRAINING AT THE UNIVERSITY OF
PENNSYLVANIA
Joan C. Hendricks
660
STRUCTURAL MUTATIONS WITHIN THE PRM AND E GENES OF
A WEST NILE VIRUS FROM MEXICO CONFER AN ATTENUATED
REPLICATION PHENOTYPE IN AVIANS
Aaron C. Brault1, Stanley A. Langevin1, Payal D. Maharaj1, Christy
C. Andrade1, Shuliu Zhang2, Richard M. Kinney3, Alan D. Barrett2,
Richard A. Bowen4, David W. Beasley2
1
University of California, Davis, Davis, CA, United States, 2University of Texas
Medical Branch, Galveston, TX, United States, 3Centers for Disease Control
and Prevention, Fort Collins, CO, United States, 4Colorado State University,
Fort Collins, CO, United States
9 a.m.
661
Flavivirus IV - West Nile Virus
ATTENUATING MUTATIONS IN THE WEST NILE VIRUS NS3
PROTEIN
Salon F
Gregory D. Ebel1, Pei-Yong Shi2, Laura D. Kramer3, Greta V.
Jerzak3, Corey J. Bennett3, Kristen A. Bernard3
Wednesday, November 7, 2007
8 a.m. - 9:45 a.m.
CHAIR
Aaron C. Brault
1
University of New Mexico School of Medicine, Albuquerque, NM, United
States, 2Wadsworth Center, Albany, NY, United States, 3Wadsworth Center,
Slingerlands, NY, United States
9:15 a.m.
662
Laura D. Kramer
Wadsworth Center, Slingerlands, NY, United States
8 a.m.
657
IN VIVO PHENOTYPIC DIFFERENCES BETWEEN WEST NILE
VIRUS GENOTYPES MAY CONTRIBUTE TO GENOTYPE DISPLACEMENT
Robin M. Moudy, Laura-Lee L. Morin, Mark A. Meola,
Laura D. Kramer
CLIMATE, EVOLUTION, AND THE TRANSMISSION OF WEST
NILE VIRUS IN MOSQUITOES
United States
A. Marm Kilpatrick1, Mark M. Meola2, Robin M. Moudy2, Noah S.
Diffenbaugh3, Laura D. Kramer2
9:30 a.m.
Consortium for Conservation Medicine, New York, NY, United States, 2New
York State Department of Health, Slingerlands, NY, United States, 3Purdue
University, West Lafayette, IN, United States
663
1
8:15 a.m.
658
INFECTION, DISSEMINATION, AND TRANSMISSION OF A WEST
NILE VIRUS GREEN FLUORESCENT PROTEIN INFECTIOUS
CLONE BY CULEX PIPIENS QUINQUEFASCIATUS MOSQUITOES
Charles E. McGee, Alexandr V. Shustov, Konstantin Tsetsarkin, Ilya
V. Frolov, Peter W. Mason, Dana L. Vanlandingham, Stephen Higgs
LONG-TERM IGM AND IGG INDEX VALUES TO WEST NILE
VIRUS IN A MULTI-VARIANT SAMPLE SET FROM NEW MEXICO
WNV SURVIVORS
Diane Goade1, Robert A. Nofchissey1, Leonor Echevarria1,
Steven Pergam2, Steve Young3, Paul Ettestad4, Charles M. Sewell4,
Larry Davis5
1
Washington, Seattle, WA, United States, 3Tricor Reference Laboratory,
Albuquerque, NM, United States, 4New Mexico Department of Health,
Santa Fe, NM, United States, 5Veteran’s Affairs Hospital, Albuquerque, NM,
United States
8:30 a.m.
659
DELIVERY OF WEST NILE VIRUS BY MOSQUITO BITE RESULTS
IN HIGHER VIREMIA, EARLIER NEUROINVASION, AND FASTER
SPREAD TO PERIPHERAL TISSUES
Linda M. Styer, Karen L. Louie, Rebecca G. Albright, Laura D.
Kramer, Kristen A. Bernard
United States
150
www.astmh.org
8:45 a.m.
667
Immunoparasitology (ACMCIP): Immunoparasitology I
Salon G
CHAIR
BRUGIA MALAYI MICROFILARIAE INHIBIT IFNγ AND TNF-α IN
RESPONSE TO MYCOBACTERIUM TUBERCULOSIS INFECTION
IN A MURINE COINFECTION MODEL
Kawsar R. Talaat1, Carl G. Feng1, Charles A. Scanga2, Margaret M.
Mentink-Kane1, Sandy White1, Thomas B. Nutman1
1
National Institute of Allergy and Infectious Diseases, Bethesda, MD, United
States, 2Aeras, Rockville, MD, United States
Lisa Ganley-Leal
Boston University School of Medicine, Boston, MA, United States
9 a.m.
668
Mary Ann McDowell
EFFECTS OF CXCL10 ON DENDRITIC CELLS AND CD4+ T CELL
FUNCTION DURING L. AMAZONENSIS INFECTION
8 a.m.
Lynn Soong, Rene E. Vasquez
664
IL-4 MEDIATES HUMAN B CELL RESPONSIVENESS TO SCHISTOSOMAL ANTIGENS
1
2
9:15 a.m.
669
3
Barbara Nikolajczyk , Pauline Mwinzi , Diana Karanja , W. Evan
Secor4, Daniel Colley5, Lisa M. Ganley-Leal1
1
Boston University School of Medicine, Boston, MA, United States, 2Kenya
Medical Research Institute, Kisian, Kenya, 3Kenya Medical Research Institute,
Kenya, Kenya, 4Centers for Disease Control and Prevention, Atlanta, GA,
United States, 5University of Georgia, Athens, GA, United States
EFFECT OF DRUG TREATMENT ON THE DEVELOPMENT OF
CD8+ T CELL MEMORY SUBSETS IN TRYPANOSOMA CRUZI
INFECTION
Juan Bustamante1, Rick Tarleton2
1
665
ABUNDANCE OF IMMUNOMODULATORY PROTEINS
REVEALED BY ANALYSIS OF THE EXCRETORY-SECRETORY (E/S)
PROTEOME OF BRUGIA MALAYI
Sasisekhar Bennuru1, Roshanak Semnani1, Jose MC Ribeiro2,
Zhaojing Meng3, Timothy D. Veenstra3, Thomas B. Nutman1
1
Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious
Diseases, National Institutes of Health, Bethesda, MD, United States,
2
Laboratory of Malaria and Vector Research, National Institute of Allergy
and Infectious Diseases, National Institutes of Health, Bethesda, MD, United
States, 3Laboratory of Proteomics and Analytical Technologies, SAICFrederick Inc., National Cancer Institute at Frederick, Frederick, MD, United
States
9:30 a.m.
670
LEISHMANIA MAJOR INDUCED INTERLEUKIN-12 EXPRESSION
IN HUMAN DENDRITIC CELLS IS MEDIATED BY NFκB, IRF-1
AND IRF-8
Asha Jayakumar1, Michael J. Donovan2, Marcelo Ramhalo-Ortigao2,
Mary Ann McDowell2
1
School of Medicine, Yale University, New Haven, CT, United States,
2
8:30 a.m.
666
COEXISTENT FILARIAL INFECTIONS DOWNREGULATE ANTIGEN-SPECIFIC TH1 AND TH17 RESPONSES IN LATENT TUBERCULOSIS: ASSOCIATION WITH ENHANCED EXPRESSION OF
CTLA-4 AND PD-1
Subash Babu1, V. Jayantasri2, S. Rukmani2, Paul Kumaran2, P. G.
Gopi2, K. Sadacharam2, V. Kumaraswami2, Thomas B. Nutman1
1
Athens, GA, United States, 2Center for Tropical and Emerging Global
Diseases and Department of Cellular Biology, University of Georgia, Athens,
GA, United States
National Institutes of Health, Bethesda, MD, United States, 2Tuberculosis
Research Centre, Chennai, India
Malaria - Epidemiology I
Salon H
8 a.m. - 9:45 a.m.
CHAIR
Gerard Killeen
Ifakara Health Research and Development Center, Dar Es Salaam, United
Ashwani Kumar
National Institute of Malaria Research, Delhi, India
151
8:15 a.m.
Detailed Program
www.astmh.org
8 a.m.
9:15 a.m.
671
676
MATHEMATICAL MODELING OF MALARIA EPIDEMIOLOGY
AND CONTROL
MALARIA IN PREGNANCY IN AN AREA WITH INCREASED BEDNET COVERAGE: A TEN-YEAR HISTORY
Nakul Chitnis1, Thomas A. Smith1, Richard Steketee2, Nicolas
Maire1, Amanda Ross1
Abdunoor M. Kabanywanyi1, John R. MacArthur2,
W. A. Stolk3, Abdullah Baja1, Vera Juma1, Charles Maswi1,
Peter B. Bloland2, Hassan Mshinda4, J. D. Habbema3,
S. Patrick Kachur2, Salim Abdulla1
1
Swiss Tropical Institute, Basel, Switzerland, 2PATH, Ferney-Voltaire, France
1
8:15 a.m.
672
COVERAGE, TARGETING AND IMPACT OF DIVERSE
MALARIA CONTROL STRATEGIES: A PRAGMATIC APPROACH
TO TRANSLATING THEORY INTO PRACTICE
GA, United States, 3University Medical Centre Rotterdam, Rotterdam, The
Netherlands, 4Ifakara Health Research and Development Centre, Dar-esSalaam, United Republic of Tanzania
9:30 a.m.
Gerry Killeen
CHANGES IN PEDIATRIC BLOOD TRANSFUSION STATISTICS AS
A POSSIBLE INDICATOR OF MALARIA CONTROL
8:30 a.m.
673
MEASURING BURDEN OF MALARIA FROM PRIMARY MORBIDITY AND MORTALITY ESTIMATES IN JHARKHAND STATE OF
INDIA-LESSONS LEARNED AND FUTURE PROSPECTS
Ashwani Kumar
National Institute of Malaria Research, Delhi, India
674
COMMUNITY-LEVEL INTERVENTION COVERAGE AND THE
BURDEN OF MALARIA IN ZAMBIA: RESULTS OF A NATIONAL
MALARIA INDICATOR SURVEY
John M. Miller1, Amara L. Robinson2, Chilandu Mukuka3,
Abdirahaman Mohamed1, Eric Sieber4, Pascalina Chanda3, Richard
W. Steketee1
1
PATH, Seattle, WA, United States, 2Consultant, Lusaka, Zambia, 3Ministry of
Health, Lusaka, Zambia, 4Ohio State University, Columbus, OH, United States
9 a.m.
675
GEOGRAPHIC AND TEMPORAL CLUSTERING OF MALARIA IN
AN URBAN COHORT OF UGANDAN CHILDREN
Bryan Greenhouse1, Tamara D. Clark1, Edmund Seto2, Moses R.
Kamya3, Denise Njama-Meya3, Bridget Nzarubara3, Philip J.
Rosenthal1, Grant Dorsey1
University of California, San Francisco, San Francisco, CA, United States,
University of California, Berkeley, Berkeley, CA, United States, 3Makerere
University School of Medicine, Kampala, Uganda
2
Philip Thuma, Janneke van Dijk, Sungano Mharakurwa
Symposium 111
Efficacy Models in New Antiparasitic Drug Discovery
Salon IJ
8:45 a.m.
1
677
The morbidity and mortality attributable to tropical diseases, particularly the
parasitic infections including malaria, leishmaniasis and trypanosomiasis
(new and old world), are staggering. Recent trends indicate rapid emergence of drug-resistant and more virulent strains of the parasites to further
intensify the problem. Continuous emergence of drug resistance not only
necessitates a high pace of new drug discovery, but also warrants building
up of an armamentarium of the drugs with proven clinical efficacy against
the current drug-resistant cases of these parasitic infections. Efficacy models
are integral parts of new drug discovery, which help in identification of new
leads and selection of the compounds for development. Recently, significant
advances have been made in assay technologies for in vitro and in vivo
antiparasitic efficacy evaluation. These advances may be useful in evaluation
of large compound libraries and high throughput screening. This symposium
would discuss recent developments in technologies and applications of efficacy models in new antiparasitic drug discovery.
CHAIR
Babu L. Tekwani
University of Mississippi, University, MS, United States
8 a.m.
KEYNOTE: APPLICATION OF TRANSFECTION TECHNOLOGY
FOR EFFICACY EVALUATION IN TROPICAL PARASITIC DISEASES
Dennis E. Kyle
University of South Florida, Tampa, FL, United States
152
www.astmh.org
8:20 a.m.
8:30 a.m.
IN VITRO EFFICACY MODELS FOR MALARIA
AND LEISHMANIASIS
ROTAVIRUS AND NOROVIRUS EPIDEMIOLOGY AND THE EVALUATION OF ROTAVIRUS VACCINE
Babu L. Tekwani
Marc-Alain Widdowson
University of Mississippi, University, MS, United States
8:40 a.m.
8:50 a.m.
IN VITRO AND IN VIVO EFFICACY MODELS FOR
TRYPANOSOMIASIS
ESTABLISHING A POPULATION-BASED SURVEILLANCE SYSTEM
FOR PNEUMONIA AND ITS ETIOLOGIES IN RURAL THAILAND
Reto Brun
Kip Baggett
Centers for Disease Control and Prevention, Nonthaburi, Thailand
9 a.m.
9:10 a.m.
HIGH THROUGH SCREENING TECHNOLOGIES FOR NEW ANTIMALARIAL DRUG DISCOVERY
Mary Lynn Baniecki
INVASIVE PNEUMOCOCCAL DISEASE AND PNEUMONIA
IN RURAL THAILAND: CAN PREVENTION BE ACHIEVED
THROUGH VACCINATION
Matthew Moore
9:20 a.m.
SCREENING NATURAL PRODUCTS AGAINST NEGLECTED
INFECTIOUS DISEASE PATHOGENS
Symposium 113
Simon L. Croft
Update on Visceral Leishmaniasis (VL) and Post KalaAzar Dermal Leishmaniasis (PKDL) Treatment in India
Symposium 112
Liberty AB
Using Population-Based Surveillance Systems in
Developing Countries as Platforms to Assess Public
Health Interventions
This symposium will explore the recent development in the treatment of
kala-azar and PKDL with sodium antimony gluconate (SAG), amphotericin B,
ambisome, miltefosine and paromomycin. It will cover methods to minimize
toxicity and improving treatment outcome.
Salon KL
CHAIR
Chandreshwar Prasad Thakur
CDC’s International Emerging Infections Programs (IEIP) are now operational
in Thailand, Kenya, Guatemala, China and Egypt. A core component of IEIPs
is population-based surveillance which can be a powerful to tool to assess
the need for and evaluate important public health interventions such as vaccines. This symposium will probe two examples, rotavirus in Kenya and
pneumococcal disease in Thailand, both of which are considering vaccine
trials or demonstration projects to reduce disease burden.
Balaji Utthan Sansthan, Patna, India
CHAIR
AMPHOTERICIN B IN THE TREATMENT OF KALA-AZAR
AND PKDL
Sonja J. Olsen
MODERATOR
Philippe Desjeux
Institute for OneWorld Health, San Francisco, CA, United States
8 a.m.
Chandreshwar Prasad Thakur
Balaji Utthan Sansthan, Patna, Bihar, India
8 a.m.
INTRODUCTION
Sonja J. Olsen
8:25 a.m.
MILTEFOSINE IN THE TREATMENT OF KALA-AZAR AND PKDL
Sujit Kumar Bhattacharya
Indian Council of Medical Research, New Delhi, India
8:10 a.m.
ESTABLISHING A POPULATION-BASED SURVEILLANCE SYSTEM
FOR PNEUMONIA, DIARRHEA, FEVER AND JAUNDICE IN
KENYA
8:50 a.m.
PAROMOMYCIN IN THE TREATMENT OF KALA-AZAR
AND PKDL
Robert Breiman
Prabhat Kumar Sinha
Centers for Disease Control and Prevention, Nairobi, Kenya
Rajendra Memorial Research Institute of Medical Sciences, Patna, India
153
Drugs for Neglected Diseases Initiative, Geneva, Switzerland
www.astmh.org
Detailed Program
9:15 a.m.
8:40 a.m.
SAG IN THE TREATMENT OF KALA-AZAR AND PKDL
A RANDOMIZED TRIAL OF DELIVERY OF IPT TO
GAMBIAN CHILDREN BY VILLAGE HEALTH WORKERS
OR VACCINATION TEAMS
Shyam Sundar
Institute of Medical Sciences, Varanasi, India
Kalifa A. Bojang
Symposium 114
Intermittent Preventive Treatment of Malaria in
Children
8:55 a.m.
A RANDOMIZED TRIAL OF IPT IN SCHOOLCHILDREN
IN UGANDA
Liberty C
Sian Clarke
Studies undertaken in Senegal and in Mali have shown that administration
of an effective antimalarial to children under the age of five years on a limited number of occasions during the peak period of malaria transmission is
highly effective at preventing malaria. However, unlike the situation for
infants, there is no easy means of distribution of antimalarials to children
beyond the age at which vaccinations are given. In this symposium, studies
will be reported which have explored different approaches to the delivery of
intermittent preventive antimalarial treatment (IPT) to older chidlren. In
Senegal and in Ghana, community volunteers have been employed to
administer IPT and the advantages and disadvantages of this apporach are
explored. In The Gambia, a randomized trial has been undertaken which
compared delivery of IPT by village health workers with delivery by vaccination teams. In Uganda, a randomized trial has been conducted of delivery of
IPT at schools. The symposium will conclude with a discussion of the next
steps needed to evaluate IPT in children as a potentially valuable malaria
control tool.
CHAIR
Brian M. Greenwood
Alassane Dicko
8 a.m.
INTRODUCTION
Brian Greenwood
9:10 a.m.
NEXT STEPS
Brian Greenwood
9:25 a.m.
DISCUSSION
Pneumonia and Respiratory Infections
Franklin 2
8 a.m. - 9:45 a.m.
CHAIR
W. Abdullah Brooks
International Center for Diarrhoeal Disease Research, B: Centre for Health
and Population Research, Dhaka, Bangladesh
Keith Klugman
8 a.m.
8:10 a.m.
PARTICIPATION OF COMMUNITY VOLUNTEERS IN THE ADMINISTRATION OF IPT IN RURAL AREAS IN SENEGAL
Badara Cisse
University of Dakar, Dakar, Senegal
8:25 a.m.
A COMPARISON OF TWO APPROACHES TO THE DELIVERY OF
IPT IN CHILDREN IN GHANA
Margaret Kweku
Ministry of Health, Hohoe, Ghana
678
A RANDOMIZED TRIAL OF AMBULATORY SHORT COURSE
HIGH DOSE ORAL AMOXICILLIN THERAPY IN THE TREATMENT
OF SEVERE PNEUMONIA IN CHILDREN
Tabish Hazir1, LeAnne M. Fox2, Yasir Bin Nisar1, Matthew P. Fox2,
Yusra Pervaiz Ashraf1, William B. MacLeod2, Afroze Ramzan3, Sajid
Maqbool4, Tahir Masood4, Waqar Hussain5, Asifa Murtaza6,
Nadeem Khawar7, Parveen Tariq8, Rai Asghar8, Donald M. Thea2,
Shamim A. Qazi9
1
ARI Research Cell, Children’s Hospital, Pakistan Institute of Medical
Sciences, Islamabad, Pakistan, 2Center for International Health and
Development, Boston University School of Public Health, Boston, MA,
United States, 3National Institute of Child Health, Karachi, Pakistan, 4The
Children’s Hospital, Lahore, Pakistan, 5Sheikh Zayed Hospital, Lahore,
Pakistan, 6Federal Government Services Hospital, Islamabad, Pakistan,
7
Khyber Medical College, Peshawar, Pakistan, 8Rawalpindi Medical College,
Rawalpindi, Pakistan, 9The Department of Child and Adolescent Health and
Development, The World Health Organization, Geneva, Switzerland
154
www.astmh.org
9:30 a.m.
679
684
EVALUATION OF A MICROCOLONY DETECTION METHOD AND
PHAGE ASSAY FOR RAPID DETECTION OF MYCOBACTERIUM
TUBERCULOSIS IN SPUTUM SAMPLES
BURDEN AND EPIDEMIOLOGY OF INFLUENZA-LIKE ILLNESS IN
A PEDIATRIC COHORT IN NICARAGUA
Seema Irfan
The Aga Khan University Hospital, Karachi, Pakistan
8:30 a.m.
680
TUBERCULIN SKIN TESTING HAS LIMITED DIAGNOSTIC
UTILITY FOR ADULT PULMONARY TUBERCULOSIS IN
ENDEMIC REGIONS
Antonino G. Curatola1, Gurjinder Sandhu2, Robert H. Gilman3,
Giselle Soto4, Antonio Bernabe1, Mayuko Saito3, Tom Pelly4, Yvonne
Ahn4, Marco Tovar1, Richard Rodriguez5, A. Roderick Escombe2,
Carlton A. Evans3
1
Faculty of Science and Philosophy, Universidad Peruana Cayetano Heredia,
Lima, Peru, 2Wellcome Centre for Clinical Tropical Medicine, Imperial College
London, London, United Kingdom, 3Johns Hopkins School University
Bloomberg, School of Public Health, Baltimore, MD, United States,
4
Asociación Benéfica PRISMA, Lima, Peru, 5Hospital Maria Auxiliadora, Lima,
Peru
8:45 a.m.
681
FATAL INFLUENZA A/H5N1 INFECTION IN A 14-YEAR-OLD
MALE PRESENTING WITH FEVER AND DIARRHEA
Dewi Lokida1, Endang Sedyaningsih2, Herman Kosasih3, Dyah
Irawati1, Shannon Putnam3, Alexander Klimov4, Patrick Blair3,
Timothy Burgess3
1
Tangerang Hospital, Tangerang, Indonesia, 2National Institute of Health
Research and Development, Jakarta, Indonesia, 3Naval Medical Research
Unit 2, Jakarta, Indonesia, 4Centers for Disease Control and Prevention,
Aubree Gordon1, Guillermina Kuan2, Oscar Ortega3, Miguel
Reyes2, Saira Saborio4, Angel Balmaseda5, Eva Harris6
1
Division of Epidemiology, School of Public Health, University of California,
Berkeley, Berkeley, CA, United States, 2Socrates Flores Vivas Health Center,
Managua, Nicaragua, 3Sustainable Sciences Institute, Managua, Nicaragua,
4
Department of Virology, Centro Nacional de Diagnóstico y Referencia,
Ministry of Health, Managua, Nicaragua, 5Departamento de Virologia,
Centro Nacional de Diagnostico y Referencia, Ministerio de Salud, Managua,
Nicaragua, 6Division of Infectious Diseases, School of Public Health,
University of California, Berkeley, Berkeley, CA, United States
Symposium 116
Poor Quality Antimalarials – Deaths, Detection and
Developments
Franklin 3/4
The poor quality of much of the world’s antimalarial drug supply is a
neglected public health problem. Since 1999 there has been an epidemic of
counterfeit oral artesunate in southeast Asia and most other antimalarials in
use have been reported as counterfeit or substandard. This has resulted in
deaths, loss of confidence in vital drugs and health systems and false reports
of clinical resistance. Substandard and counterfeit drugs containing subtherapeutic amounts of active ingredients are potentially important drivers
of antimalarial drug resistance. There is increasing concern that fake
artemisinin derivatives will become a major problem in Africa, reducing the
beneficial public health impact of these crucial medicines. New methods for
the rapid, inexpensive detection of poor quality antimalarials, as well as
sophisticated, non-invasive, innovative methods for the identifying the ingredients of fakes and their forensic fingerprints, will also be presented.
CHAIR
Harparkash Kaur
London School of Hygiene & Tropical Medicine, London, United Kingdom
9 a.m.
682
H5N1 OUTBREAK IN BURKINA FASO
Zekiba Tarnagda1, Adele Kam1, Marc Christian Tahita1, Issaka
Yougbare1, Mariette M.F. Ducatez2, Claude P. Muller2, Jean-Bosco
Ouedraogo1
IRSS, Bobo-Dioulasso, Burkina Faso, 2LNS, Luxembourg, Luxembourg
Paul Newton
Mahosot Hospital, Vientiane, Lao People’s Democratic Republic
Nicholas White
Wellcome Trust-Mahidol University-Oxford Tropical Medicine Research
Programme, Bangkok, Thailand
1
9:15 a.m.
8 a.m.
INTRODUCTION
683
PREPAREDNESS FOR PANDEMIC INFLUENZA IN A DEVELOPING
COUNTRY: KNOWLEDGE, ATTITUDES AND PRACTICES
CONCERNING INFLUENZA CONTROL IN PERUVIAN NAVY
HEALTH CARE FACILITIES
Roger V. Araujo Castillo1, Daphne Ponce1, Carmen C. Mundaca1,
Emilia Saldarriaga2, Manuel Moran2, Miguel Fernandez2,
David L. Blazes1
1
Naval Medical Research Center Detachment, Lima, Peru, 2Centro Medico
Naval, Lima, Peru
Paul Newton
Nicholas White
Wellcome Trust Mahidol University Oxford Tropical, Bangkok, Thailand
8:15 a.m.
SIMPLE, LOW-COST METHODS TO RAPIDLY IDENTIFY COUNTERFEIT DRUGS
Michael D. Green
155
8:15 a.m.
www.astmh.org
Detailed Program
8:35 a.m.
Symposium 117
USER-FRIENDLY COLOR TESTS TO SPOT CHECK ARTEMISININ
DRUG CONTENT
The Global Enteric Multi-Center Study (GEMS)
Harparkash Kaur
Salon AB
8:55 a.m.
A NEW GENERATION OF RAPID AND SENSITIVE
LABORATORY TECHNIQUES FOR ASSESSING DRUG
QUALITY AND DETECTING COUNTERFEIT DRUGS:
APPLICATIONS TO ANTIMALARIALS
Facundo M. Fernandez
Georgia Institute of Technology, Atlanta, GA, United States
9:15 a.m.
AN INVESTIGATION INTO THE SOURCE OF COUNTERFEIT
ARTESUNATE
Aline Plançon-Lecadre
Interpol, Lyon, France
Paul Newton
Exhibit Hall Open
Franklin Hall B
Wednesday, November 7, 2007 9:30 a.m. - 10:30 a.m.
Coffee Break
Wednesday, November 7, 2007 10:15 a.m. - Noon
WHO ranks diarrheal disease as the second most common cause of mortality among children younger than 60 months of age in developing countries,
accounting for 18% of the 10.6 million children in this age group who die
each year. With few exceptions, however, data from studies previously
undertaken to determine the etiology of these illnesses suffer from some
notable deficiencies. The shortcomings of available data include lack of a
censused population to permit disease incidence to be calculated, lack of
follow-up to detect sequelae (adverse clinical consequences), lack of appreciation of distinct presentations (non-bloody diarrhea, profuse watery diarrhea, dysentery and persistent diarrhea) and lack of detection or comprehensive analysis of new and emerging pathogens. Also, few studies measure
the financial cost of a child’s diarrheal illness to the family and to the health
care system to derive a comprehensive picture of the burden of disease;
economic cost is particularly neglected. But the most remarkable deficiency
is the paucity of systematic studies in the countries that bear the highest
childhood mortality rates, most of which reside in sub-Saharan Africa.
Accordingly, to fill these knowledge gaps and generate critical information
to allow establishment of priorities for disease control, including but not
limited to enteric vaccine development, design of vaccines for broad coverage, formulation of effective public health policy and appropriate focus of
emerging interventions, the Center for Vaccine Development of the
University of Maryland School of Medicine, with funding from the Bill and
Melinda Gates Foundation, has initiated with a consortium of partners a
multi-site (Bangladesh, Gambia, India, Kenya, Mali, Mozambique, Pakistan)
study of the etiology, burden and sequelae of diarrheal diseases from eight
highly affected, heterogeneous, geographic and epidemiologic settings.
CHAIR
Franklin Hall B
Myron M. Levine
Wednesday, November 7, 2007 9:45 a.m. - 10:15 a.m.
Poster Session C Set-Up
10:15 a.m.
Franklin Hall B
9:45 a.m. - 10:15 a.m.
Franklin Hall B
10:15 a.m. - Noon
OVERVIEW OF GEMS
Myron M. Levine
10:30 a.m.
EPIDEMIOLOGIC AND CLINICAL ISSUES
Karen L. Kotloff
10:45 a.m.
MICROBIOLOGICAL ISSUES AND METHODS
James P. Nataro
11 a.m.
MANHICA, MOZAMBIQUE
Pedro L. Alonso
Centro de Investigation em Saúde da Manhica, Manhica, Maputo,
Mozambique
156
11:15 a.m.
11:25 a.m.
BAMAKO, MALI
Samba O. Sow
WORK CARRIED OUT UNDER THE BWF/ASTMH
PROGRAM’S SUPPORT
Center for Vaccine Development-Mali, Bamako, Mali
Danny A. Milner
www.astmh.org
The Brigham & Women’s Hospital, Boston, MA, United States
11:30 a.m.
KISUMU, KENYA
Symposium 119
Robert Breiman
Centers for Disease Control and Prevention - KEMRI Research Station,
Kisumu, Kenya
The Development and Evaluation of Diagnostics for
Tropical Diseases
11:45 a.m.
Salon E
BASSE, THE GAMBIA
Richard A. Adegbola
This symposium is designed to review and update progress on the development and evaluation of diagnostics for selected tropical diseases. The speakers will describe work supported by the UNICEF/UNDP/World Bank/WHO
Special Programme for Research and Training in Tropical Diseases
(WHO/TDR).
Symposium 118
Launching Careers In Tropical Disease Research:
Progress Reports From Burroughs Wellcome
Fund/ASTMH and Fogarty International Center IRDSA
Fellows
CHAIR
DIAGNOSIS OF VISCERAL LEISHMANIASIS - WHERE ARE WE?
Salon CD
Shyam Sundar
Banaras Hindu University, Varanasi, India
This session will highlight the work of several BWF/ASTMH and Fogarty
International Center fellows who are focusing their work on global health
problems in situ — doing excellent research on tropical diseases where they
occur. Both of these highly competitive fellowship programs focus on training
excellent generally U.S.-based researchers who are launching research careers
that are expected to involve long-term research presence both abroad and at
their home institutions in the States. This session will be followed by a
lunchtime discussion of career issues faced by those who take on working in
two countries (home and abroad).
10:40 a.m.
CHAIR
Victoria McGovern
Rosanna W. Peeling
10:15 a.m.
EVOLUTION OF DIAGNOSTICS ON HUMAN AFRICAN
TRYPANOSOMIASIS, WITH SPECIAL EMPHASIS ON
SLEEP-WAKE DISTURBANCES
Alain G. Buguet
Université Claude-Bernard Lyon I, Lyon, France
11:05 a.m.
UTILITY OF EXISTING DIAGNOSTIC TESTS FOR
S. MANSONI AND S. HAEMATOBIUM IN AREAS OF
LOW INTENSITY TRANSMISSION
Barbara Sina
Diana M. Karanja
Fogarty International Center, National Institutes of Health, Bethesda, MD,
United States
11:30 a.m.
10:15 a.m.
WORK CARRIED OUT UNDER THE FOGARTY
PROGRAM’S SUPPORT
Regina LaRocque
EVALUATION OF ANTIGEN AND ANTIBODY DETECTIONS FOR
DIAGNOSIS OF DENGUE VIRUS INFECTION
Sutee Yoksan
Mahidol University at Salaya, Bangkok, Thailand
10:50 a.m.
WORK CARRIED OUT UNDER THE FOGARTY
PROGRAM’S SUPPORT
Mina Hosseinipour
University of North Carolina School of Medicine, Chapel Hill, NC, United
States
157
Detailed Program
www.astmh.org
11:15 a.m.
689
Flavivirus V
CHARACTERIZATION OF THE BARKEDJI VIRUS, A NEW MOSQUITO-BORNE FLAVIVIRUS ISOLATED IN SENEGAL
Salon F
10:15 a.m. - Noon
Anne Dupressoir1, Pablo M. de A Zanotto2, Juliana Velasco de
Castro Oliveira2, Lang Girault1, Magueye Ndiaye1, Mireille Mondo1,
Amadou Alpha Sall1
CHAIR
1
Rebecca M. Robich
(ACMCIP Abstract)
Tom Solomon
11:30 a.m.
690
10:15 a.m.
CHIKUNGUNYA FEVER IN MAURITIUS, 2006
685
CONUNDRUMS IN EVOLUTION OF JAPANESE ENCEPHALITIS
VIRUS
1
Institut Pasteur Dakar, Dakar, Senegal, 2Laboratório de Evolução Molecular
e Bioinformática, Sao Paulo, Brazil
1
1
Janet Shaw , Wipa Tangkananond , Jennifer Collett , Allison
German1, Curtis G. Hayes2, Patrick J. Blair3, Tom Solomon1
1
University of Liverpool, Liverpool, United Kingdom, 2Naval Medical Research
Center, Silver Spring, MD, United States, 3Naval Medical Research Unit No 2,
Jakarta Pusat, Indonesia
Sanjay Beesoon1, Navaratnam Kotea1, Andrew Spielman2,
Rebecca M. Robich2
1
University of Mauritius, Moka, Mauritius, 2Harvard School of Public Health,
Boston, MA, United States
11:45 a.m.
691
PATHOGENESIS OF CHIKUNGUNYA VIRUS INFECTION IN MICE
10:30 a.m.
Sarah A. Ziegler, Liang Lu, Shu-Yuan Xiao, Robert B. Tesh
686
DEFINITION OF THE MAJOR DETERMINANT RESPONSIBLE FOR
NEUROVIULENCE OF JAPANESE ENCEPHALITIS VIRUS
Yoko Nukui, Shigeru Tajima, Chang kweng Lim, Reiko Nerome,
Tomohiko Takasaki, Ichiro Kurane
Department of Virology I, National Institute of Infectious Diseases,
Tokyo, Japan
10:45 a.m.
Immunoparasitology (ACMCIP): Immunoparasitology II
Salon G
687
EFFECT OF PRE-EXISTING ANTI TICK BORNE ENCEPHALITIS
VIRUS (TBE) IMMUNITY ON NEUTRALIZING ANTIBODY
RESPONSE TO THE NOVEL, VERO CELL DERIVED INACTIVATED
JAPANESE ENCEPHALITIS VIRUS (JEV) VACCINE IC51
Elisabeth Schuller1, Christoph Klade1, Christa Firbas2, Karin
Stiasny3, Franz X Heinz3, Pamela Rendi- Wagner4, Bernd Jilma2,
Erich Tauber1
1
Intercell AG, Vienna, Austria, 2Medical University Vienna, Clinical
Pharmacology, Vienna, Austria, 3Institute for Virology, Medical University
Vienna, Vienna, Austria, 4Medical University Vienna, Specific Prophylaxis and
Tropical Medicine at Institute Pathophysiology, Vienna, Austria
CHAIR
Nadia Sam-Agudu
University of Minnesota, Farmington, MN, United States
Michael Walther
MRC Laboratories Fajara, Banjul, Gambia
10:15 a.m.
1071
A ROLE FOR IRF-7 IN REGULATING THE INTRACELLULAR FATE
OF LEISHMANIA DONOVANI
Rebecca Phillips1, M. Svensson2, P. Kaye1
11 a.m.
688
1
University of York and the Hull York Medical School, York, United Kingdom,
Karolinska University Hospital, Stockholm, Sweden
2
MIGRATION AND TRANSMISSION HISTORY OF ST. LOUIS
ENCEPHALITIS VIRUS
Albert J. Auguste1, Eleca J. Dunham2, Oliver G. Pybus3, Edward C.
Holmes2, Christine V. Carrington1
1
University of the West Indies, St. Augustine, Trinidad and Tobago,
Pennsylvania State University, State College, PA, United States, 3University
of Oxford, Oxford, United Kingdom
2
158
10:30 a.m.
www.astmh.org
1072
PRESENCE OF AN IL-7R∞HI MEMORY CD8+ T CELL POPULATION DURING PERSISTENT TRYPANOSOMA CRUZI INFECTION
Malaria - Epidemiology II
Salon H
Lisa M. Bixby, Juan M. Bustamante, Matthew H. Collins, Rick L.
Tarleton
Mônica da Silva-Nunes
CHAIR
Universidade de Sao Paulo, Sao Paulo - SP, Brazil
692
Philip Thuma
CYTOKINE-ASSOCIATED NEUTROPHIL EXTRACELLULAR TRAPS
AND ANTINUCLEAR ANTIBODIES IN PLASMODIUM FALCIPARUM INFECTED CHILDREN UNDER THE AGE OF SIX
10:15 a.m.
Virginia S. Baker1, Godwin Imade2, Norman Molta3, Sunday Pam2,
Michael Obadofin2, Solomon Sagay2, Daniel Egah2, Daniel Iya2,
Bangmboye Afolabi4, Murray Baker5, Karen Ford6, Robert Ford6,
Kenneth Roux1, Thomas Keller1
RISK FACTORS FOR MALARIA IN A RURAL AMAZONIAN
COHORT (GRANADA, ACRE, BRAZIL)
1
Florida State University, Tallahassee, FL, United States, 2Jos University
Teaching Hospital and Medical School, Jos, Nigeria, 3Jos University, Jos,
Nigeria, 4Nigerian Ministry of Health/WHO, Abuja/Lagos, Nigeria, 5Jackson
Hospital/Flowers Hospital, Marianna/Dothan, FL, United States, 6World
Health Mission, Pittsburgh, PA, United States
11 a.m.
693
HIV INFECTION IMPAIRS OPSONIC PHAGOCYTOSIS OF
PLASMODIUM FALCIPARUM-INFECTED ERYTHROCYTES
Stephen Rogerson1, Liselle Fernandes2, Francisca Yosaatmadja1,
Victor Mwapasa3, Malcolm Molyneux3, Eyob Tadesse4, Steven
Meshnick5, Anthony Jaworowski2
1
University of Melbourne, Parkville Victoria, Australia, 2Burnet Institute,
Prahran, Victoria, Australia, 3Malawi-Liverpool-Wellcome Trust Clinical
Research Programme, Blantyre, Malawi, 4College of Medicine, University of
Malawi, Blantyre, Malawi, 5University of North Carolina, Chapel Hill, NC,
United States
11:15 a.m.
695
TLR9 POLYMORPHISMS ARE ASSOCIATED WITH ALTERED
IFN-γ LEVELS IN CHILDREN WITH CEREBRAL MALARIA
Nadia A. Sam-Agudu1, Jennifer Greene2, Robert O. Opoka3,
James W. Kazura2, Michael J. Boivin4, Lisa A. Schimmenti1, Peter A.
1
University of Minnesota Children’s Hospital-Fairview, Minneapolis, MN,
United States, 2Case Western Reserve University, Cleveland, OH, United
States, 3Makerere University, Kampala, Uganda, 4Michigan State University,
East Lansing, MI, United States
697
Mônica da Silva-Nunes1, Natália T. Komatsu1, Camlia Juncansen1,
Rosane R. DÁrcádia1, Erika H. Hoffmann1, Estéfano A. Souza1,
Natal S. Silva1, Melissa S. Bastos2, Sandra L. Moraes-Ávila2, Rosely S.
Malafronte2, Kézia K. Scopel3, Érika M. Braga3, Carlos E. Cavasini4,
Pascoal T. Muniz5, Irene S. Soares1, Marcelo U. Ferreira1
1
Universidade de São Paulo, São Paulo - SP, Brazil, 2Instituto de Medicina
Tropical, São Paulo - SP, Brazil, 3Universidade Federal de Minas Gerais, Belo
Horizonte - MG, Brazil, 4Faculdade de Medicina de São José do Rio Preto,
São José do Rio Preto - SP, Brazil, 5Universidade Federal do Acre, Rio Branco
- AC, Brazil
10:30 a.m.
698
INDIVIDUAL AND HOUSEHOLD LEVEL FACTORS ASSOCIATED
WITH MALARIA INCIDENCE IN NAZARETH, ETHIOPIA
Ingrid Peterson1, Awash Teklehaimanot2
1
New York University - Medical Parasitology, New York, NY, United States,
Columbia University - Department. of Epidemiology, New York, NY, United
States
2
10:45 a.m.
699
MULTILEVEL ANALYSIS OF SOCIAL, ECOLOGICAL, AND
BIOLOGICAL PREDICTORS OF POLYPARASITISM IN COASTAL
KENYA
Lia S. Florey1, Melissa K. Van Dyke1, Charles H. King2, Eric M.
Muchiri3, Peter L. Mungai4, Peter A. Zimmerman2, Mark L. Wilson1
1
University of Michigan, Ann Arbor, MI, United States, 2Case Western
Reserve University, Cleveland, OH, United States, 3Division of Vector Borne
Diseases, Ministry of Health, Nairobi, Kenya, 4Msambweni Field Station,
Msambweni, Kenya
11:30 a.m.
696
THE ROLE OF IMMUNOREGULATORY CELLS IN NATURAL
IMMUNITY TO PLASMODIUM FALCIPARUM
Olivia Finney1, Michael Walther1, Patrick Corran2, David Conway1,
Eleanor Riley2
1
MRC, Banjul, Gambia, 2London School of Hygiene and Tropical Medicine,
159
10:45 a.m.
Detailed Program
www.astmh.org
11 a.m.
Symposium 123
700
New Drugs/Drug Targets for Schistosomiasis
INTEGRATING ONE OF THE NTDS WITH ONE OF THE
BIG THREE. AN INTEGRATED MALARIA INDICATOR,
PARASITE PREVALENCE, TRACHOMA INDICATOR, AND
TRACHOMA PREVALENCE SURVEY IN AMHARA
REGIONAL STATE, ETHIOPIA
Salon IJ
Paul Emerson1, Yeshewamebrat Ejigsemahu2, Estifanos Biru2,
Patricia Graves1, Jeremiah Ngondi1, Asrat Genet3, Teshome Gebre2,
Tekola Endeshaw2, Aryc Mosher1, Frank Richards1
1
The Carter Center, Atlanta, GA, United States, 2The Carter Center, Addis
Ababa, Ethiopia, 3Amhara Regional Health Bureau, Bahir Dar, Ethiopia
11:15 a.m.
The control of schistosomiasis largely depends on the use of a single drug,
praziquantel. This symposium is designed to review and update progress in
the effort to develop new drugs for schistosomiasis. These will include an
analysis of the use of artemisinins, investigations on the efficacy of simplified artemisinins, ozonides (trioxolanes), and the discussion of two high
throughput screens of chemical libraries to identify new targets and lead
compounds for drug development. The screens were directed against (1)
whole parasites and (2) parasite antioxidant enzymes.
CHAIR
701
David L. Williams
SEVERE DISEASE ASSOCIATED WITH BOTH P. FALCIPARUM
AND P. VIVAX INFECTION IN PAPUA, INDONESIA
E. Tjitra1, N. M. Anstey2, N. M. Warrikar3, E. Kenangalem4, D. A.
Lampah5, M. Karyana1, P. Sugiarto6, R. N. Price2
Southwest Foundation for Biomedical Research, San Antonio, TX, United
States
Philip T. LoVerde
1National Institute of Health Research and Development, Jakarta, Indonesia,
2Menzies School of Health Research, Darwin, Australia, 3International SOS,
Timika, Indonesia, Timika, Indonesia, 4Dinas Kesehatan Kabupaten, Timika,
Indonesia, 5International Health Program, Timika, Indonesia, 6Rumah Sakit
Mitra Masyarakat, Timika, Indonesia
11:30 a.m.
10:15 a.m.
NOVEL DRUGS FOR SCHISTOSOMIASIS: ESTABLISHMENT OF A
MEDIUM-THROUGHPUT WHOLE-ORGANISM SCREEN AT
UNIVERSITY OF CALIFORNIA AT SAN FRANCISCO
Conor Caffrey
Sandler Center for Basic Research in Parasitic Diseases, San Francisco, CA,
United States
702
BLOOD GROUP O PROTECTS AGAINST SEVERE PLASMODIUM
FALCIPARUM MALARIA
J. Alexandra Rowe, Anne-Marie Deans
Institute of Immunology and Infection Research, Unversity of Edinburgh,
United Kingdom
10:45 a.m.
HIGH THROUGHPUT SCREEN OF A SMALL CHEMICAL LIBRARY
FOR INHIBORS OF SCHISTOSOME REDOX ENZYMES
Ahmed A. Sayed
11:45 a.m.
703
11:10 a.m.
IMPACT OF MATERNAL MALARIA AND UNDER-NUTRITION ON
INTRAUTERINE GROWTH RESTRICTION: A PROSPECTIVE
COHORT STUDY IN DEMOCRATIC REPUBLIC OF CONGO
UTILITY OF THE ARTEMISININS IN THE CHEMOTHERAPY OF
SCHISTOSOMIASIS
Juerg Utzinger
Sarah Landis , Victor Lokomba , Joseph Atibu , Cande Ananth ,
Robert Ryder4, Katherine Hartmann5, John Thorp1, Antoinette
Tshefu2, Steven Meshnick1
1University of North Carolina-Chapel Hill, Chapel Hill, NC, United States,
2University of North Carolina-DRC Project, Kinshasa, Democratic Republic of
the Congo, 3University of Medicine and Dentistry of New Jersey-Robert
Wood Johnson Medical School, New Brunswick, NJ, United States, 4Boston
University School of Public Health, Boston, MA, United States, 5Vanderbilt
University Medical Center, Nashville, TN, United States
FROM THE ARTEMISININS TO THE OZONIDES (TRIOXOLANES):
A MEDICINAL CHEMIST’S PERSPECTIVE
1
2
2
3
11:25 a.m.
Jonathan L. Vennerstrom
University of Nebraska Medical Center, Omaha, NE, United States
11:35 a.m.
OZONIDES (TRIOXOLANES) AND OTHER PEROXIDES AS
POTENTIAL THERAPEUTICS FOR SCHISTOSOMIASIS AND
OTHER TREMATODE INFECTIONS
Jennifer Keiser
160
11:50 a.m.
11:40 a.m.
NEW DRUGS FOR SCHISTOSOMIASIS AND OTHER
TREMATODE-BORNE DISEASES: WHAT DID WE LEARN
AND A WAY FORWARD
MODERATED PANEL DISCUSSION
www.astmh.org
Symposium 125
Marcel Tanner
Symposium 124
Foreign Militaries and International Public Health
Surveillance: Untapped Resources?
Salon KL
Foreign militaries may be an untapped resource for country-specific public
health surveillance data and response capacity. Many track the health of
both military populations and otherwise inaccessible civilian populations.
Speakers will discuss advantages and drawbacks of better integrating militaries into international public health surveillance and response efforts, followed by a discussion.
CHAIR
J. Jeremy Sueker
DoD Global Emerging Infections Surveillance and Response System, Silver
Strongyloidiasis: Recent Clinical and
Immunologic Observations
Liberty AB
Strongyloidiasis is among the most severe of the helminth infections, yet relatively little attention has been paid to this organism. This symposium will
highlight recent developments on the burden of disease, recognition of a
wider spectrum of disease including the importance of HTLV-1 in dissemination, the role of ivermectin in treatment and newer diagnostic tests. Finally,
recent studies have highlighted the role of the host response in control of
infection in animal models and human subjects.
CHAIR
A. Clinton White
Martin Montes
10:15 a.m.
10:15 a.m.
THE BIOLOGY OF STRONGYLOIDES
PERSPECTIVES FROM WHO: CURRENT COLLABORATIONS,
FUTURE POSSIBILITIES AND POLICY IMPLICATIONS
Thomas J. Nolan
Matthew Lim
United States
10:30 a.m.
10:40 a.m.
GLOBAL BURDEN OF DISEASE CAUSED
BY STRONGYLOIDIASIS
ARGUMENTS FOR GREATER INTERNATIONAL COLLABORATION: OVERVIEW AND NATO PERSPECTIVES
Edita Stok
Chair, Joint Medical Committee, North Atlantic Treaty Organization, Brussels,
Belgium
11 a.m.
Pablo Peñataro-Yori
10:45 a.m.
CLINICAL SPECTRUM AND TREATMENT OF
STRONGYLOIDIASIS
CASE STUDY: THE EXPERIENCES OF THE ROYAL THAI ARMY IN
BILATERAL AND INTERNATIONAL COLLABORATION
Eduardo Gotuzzo
Jariyanart Gaywee
11:10 a.m.
Armed Forces Research Institute of Medical Sciences - Royal Thai Army,
Bangkok, Thailand
UPDATE ON DIAGNOSIS OF STRONGYLOIDIASIS
J. Dick MacLean
11:20 a.m.
McGill University Center for Tropical Disease, Montreal, QC, Canada
REASONS FOR CAUTION: HISTORICAL INTERACTIONS AND
CONTEMPORARY REALITIES
11:25 a.m.
Trueman W. Sharp
IMMUNOLOGIC CONTROL OF INFECTION IN ANIMAL MODELS
States
David Abraham
161
www.astmh.org
Detailed Program
11:40 a.m.
11:35 a.m.
IMMUNOLOGIC CONTROL OF INFECTION IN
HUMAN SUBJECTS
INTERMITTENT PREVENTIVE TREATMENT IN INFANTS (IPTI)
WITH AMODIAQUINE/ARTESUNATE, SP/ARTESUNATE OR
CHLORPROGUANIL-DAPSONE IN WESTERN KENYA: A RANDOMIZED PLACEBO-CONTROLLED, DOUBLE-BLIND TRIAL
Martin Montes
Instituto de Medicina Tropical ‘Alexander von Humboldt, Lima, Peru
Frank O. Odhiambo
Symposium 126
Centers for Disease Control and Prevention-KEMRI, Kisumu, Kenya
Update from the Intermittent Preventive Treatment in
Infants (IPTi) Consortium: Status of Policy Change and
Program Implementation, and the Efficacy SulfadoxinePyrimethamine (SP) and Other Antimalarial Drugs
Symposium 126A
Liberty C
This symposium is designed to address the need for adjuvants for a new
generation of vaccines against neglected diseases. Topics to be discussed
will include TLR agonists as adjuvants, the importance of formulation and
accessibility of adjuvants for vaccine development outside of industry.
The symposium will provide an update on the progress of the IPTi
Consortium. An update will be provided on the efficacy of IPTi with SP.
Information will be presented regarding the applicability of IPT as a strategy
in various African settings. Lessons learned will be discussed from the
UNICEF pilot implementation experiences with IPTi in several countries in
Africa. The status of the policy review process at WHO will be reviewed.
New evidence regarding regimens other than sulfadoxine-pyrimethamine
(SP) for use as IPTi will be shared.
CHAIR
Robert D. Newman
10:15 a.m.
UPDATE ON EFFICACY TRIALS OF IPTI WITH SULFADOXINEPYRIMETHAMINE
Martin P. Grobusch
University of the Witwatersrand, Johannesburg, South Africa
10:35 a.m.
INTERMITTENT PREVENTIVE TREATMENT (IPT) FOR AFRICAN
CHILDREN: WHERE AND HOW SHOULD IPT BE APPLIED?
Ilona Carneiro
Adjuvants for a New Generation of Vaccines
Franklin 1
CHAIR
Steven G. Reed
Infectious Disease Research Instsitute, Seattle, WA, United States
10:15 a.m.
INTRODUCTION
Steven G. Reed
Infectious Disease Research Instsitute, Seattle, WA, United States
10:40 a.m.
OVERVIEW OF ADJUVANTS AND INTRODUCTION OF ADJUNET
Steven G. Reed
11 a.m.
ADJUVANT FORMULATIONS AND PRACTICAL ISSUES
Martin Friede
11:20 a.m.
10:55 a.m.
TLR AGONISTS AS VACCINE ADJUVANTS
UPDATE ON THE ADOPTION OF INTERMITTENT PREVENTIVE
TREATMENT IN INFANTS (IPTI) WITH SP INTO POLICY IN SUBSAHARAN AFRICA
Robert Seder
Andrea Egan
11:40 a.m.
Hospital Clinic - University of Barcelona, Barcelona, Spain
ADJUVANTS FOR MALARIA VACCINES
11:15 a.m.
Allan Saul
UNICEF PILOT IMPLEMENTATION OF INTERMITTENT
PREVENTIVE TREATMENT IN INFANTS (IPTI)
Alexandra de Sousa
162
www.astmh.org
Symposium 127
Bridging Pathogenesis and Pathology in Malaria:
Addressing Drug Resistance and Tolerance in Malaria
Parasites
HIV in the Tropics
CHAIR
Franklin 2
Davidson H. Hamer
Boston University School of Public Health, Boston, MA, United States
Linking parasite biology and genomics to drug therapies remains a frontier
in malaria. This has created great need for broad, integrated perspectives to
understand the complexities of pathogenic mechanisms, and drug treatment
modalities. This symposium will bring together recent studies in malaria
treatment regiments, drugs and their targets to integrate basic research
approaches with clinical disease and the development of therapeutics.
Jean B. Nachega
CHAIR
THE COSTS OF HIV TREATMENT IN DEVELOPING COUNTRIES:
EFFECTS OF PROGRAM MATURITY, CONTEXT AND DESIGN ON
TOTAL AND COMPONENT COSTS
Kasturi Haldar
Northwestern University, Chicago, IL United States
Franklin 3/4
10:15 a.m.
704
Scott Filler, The ART Costing Study Team
Akhil B. Vaidya
Drexel University College of Medicine, Philadelphia, United States
10:15 a.m.
10:30 a.m.
705
GENETIC DIVERSITY AND DRUG-RESISTANT MALARIA
10:40 a.m.
TARGETING MITOCHONDRIAL FUNCTION IN DRUG DEVELOPMENT AND TOLERANCE
Akhil B. Vaidya
DRAMATIC REDUCTIONS IN HIV RNA AMONG HIV-INFECTED
CHILDREN WITH ACUTE MEASLES IN UGANDA
Jane Achan1, Theodore D. Ruel2, Anne F. Gasasira1, Edwin D.
Charlebois2, Philip J. Rosenthal2, Grant Dorsey2, Moses R. Kamya1,
Adeodata Kekitiinwa3, Joseph Wong2, Diane Havlir2
1
Makerere University, Kampala, Uganda, 2 University of California at San
Francisco, San Francisco, CA, United States, 3Baylor College of Medicine,
Pediatric Infectious Disease Clinic, Mulago Hospital, Kampala, Uganda
10:45 a.m.
11:05 a.m.
COMBINING HOST TARGETED THERAPIES IN CONJUNCTION
WITH CONVENTIONAL ANTI-MALARIALS
Kasturi Haldar
11:30 a.m.
TAFENOQUINE IN TREATMENT OF P. FALCIPARUM AND P.
VIVAX MALARIA
Wilbur K. Milhous
Walter Reed Army Institute of Research, Silver Spring, United States
706
HIV-1 INFECTION IN PATIENTS REFERRED FOR MALARIA
BLOOD SMEARS AT UGANDAN GOVERNMENT HEALTH CLINICS
Lisa M. Bebell1, Anne Gasasira2, Moses Kiggundu2, Christian
Dokomajilar3, Moses R. Kamya2, Edwin Charlebois3, Diane Havlir3,
Philip Rosenthal3, Grant Dorsey3
1
Columbia University College of Physicians and Surgeons, New York, NY,
United States, 2Makerere University Medical School, Kampala, Uganda,
3
11 a.m.
707
HEMATOLOGICAL AND INFLAMMATORY MEDIATOR ANALYSES IN KENYAN CHILDREN WITH PLASMODIUM FALCIPARUM
AND HIV-1 CO-INFECTION
Gregory Davenport1, Richard Otieno2, Collins Ouma2, James
Hittner3, Tom Were2, Yamo Ouma2, Amos K’Ogal2, John Vulule4,
John Michael Ong’echa2, Gordon Awandare1, Douglas Perkins1
1
University of Pittsburgh, Pittsburgh, PA, United States, 2University of
Pittsburgh/KEMRI, Kisumu, Kenya, 3College of Charleston, Charleston, SC,
United States, 4KEMRI, Kisumu, Kenya
(ACMCIP Abstract)
163
Drexel University College of Medicine, Philadelphia, United States
Detailed Program
www.astmh.org
11:15 a.m.
712
708
CLINICAL MENTORING: EFFECTIVE AND RAPID TOOL
IMPROVES CLINICAL CARE SKILLS FOR TB/HIV IN
DEVELOPING COUNTRIES
Mario Onagan1, Larisa Bomlitz2, Katie Graves-Abe2, Marie Charles2
1
Family Health International, Research Triangle Park, NC, United States,
International Center for Equal Healthcare Access, New York, NY,
United States
2
CONGENITAL AND NEONATAL MALARIA IN A TERTIARY REFERENCE HOSPITAL IN MALI
Mariam Sylla1, Dicko-Traore Fatoumata1, Antoine Dara2,
Souleymane Dama2, Kalirou Traore1, Pierre Togo1, Seydou Traore1,
Sibiry Sissoko2, Belco Poudiougo2, Mamadou M. Keita1, Ogobara K.
Doumbo2, Abdoulaye A. Djimde2
1
Service de Pediatrie, Hopital Gabriel Toure, Bamako, Mali, 2University of
Bamako, Bamako, Mali
713
11:30 a.m.
THE ECOLOGY AND BIOGEOGRAPHY OF MELIOIDOSIS IN
PAPUA NEW GUINEA
709
IMPACT OF SPIRULINA PLATENSIS SUPPLEMENTATION ON
GENERAL HEALTH STATUS OF HIV INFECTED PEOPLE IN
BURKINA FASO
1
1
1
Zekiba Tarnagda , Issaka Yougbare , Aboubacar Siribie , Augustin
N. Zeba1, Daouda Mare2, Zourata Lompo3, Zourata Lompo4, Jean
Baptiste Nikiema4, Jean-Bosco Ouedraogo1
1
2
IRSS, Bobo-Dioulasso, Burkina Faso, REVS+, Bobo-Dioulasso, Burkina Faso,
Universite de Ouagadougou, Bobo-Dioulasso, Burkina Faso, 4Universite de
Ouagadougou, Ouagadougou, Burkina Faso
3
11:45 a.m.
710
CO-INFECTION OF CUTANEOUS LEISHMANIASIS AND HIV IN
MALI
Ousmane Faye1, Seydou Doumbia2, Pierre Traore3, Coulibaly Karim3,
A. Dicko3, Hawa Sagara3, Hawa Ndiaye3, Somita Keita3
1
National Center for Disease Control, CNAM/Intitut Marchoux, Bamako,
Mali, 2Malaria Research and Training Center, Bamako, Mali, 3National Center
for Disease Control, Intitut Marchoux, Bamako, Mali
Wayne Melrose1, Anthony Baker1, Kristy Marshall1, Jeffrey
Warner1, Gabriel Padilla1, Warren Shipton2
1
James Cook University, Townsville, Australia, 2Mission College, Muak Lek,
Saraburi, Thailand
714
EFFICACY OF SINGLE DOSE LEVOFLOXACIN FOR TREATMENT
OF ACUTE LEPTOSPIROSIS IN A HAMSTER MODEL
Matthew Griffith, Suzanne McCall, Duane Hospenthal,
Clinton Murray
Brooke Army Medical Center, Ft. Sam Houston, TX, United States
715
ANTIMICROBIAL SUSCEPTIBILITY OF CLINICAL LEPTOSPIRA
ISOLATES
Matthew Griffith1, Miriam Beckius1, Guillermo Pimentel2,
Roseanne Ressner1, Duane Hospenthal1, Clinton Murray1
1
Brooke Army Medical Center, Ft. Sam Houston, TX, United States, 2U.S.
Naval Medical Research Unit #3, Cairo, Egypt
716
Exhibit Hall Open
Wednesday, November 7, 2007 Noon - 2:30 p.m.
EFFECTS OF A HIGH FAT MEAL ON THE BIOAVAILABILITY OF
THE FIXED-DOSE COMBINATION OF AMODIAQUINE AND
ARTESUNATE (ASAQ) IN HEALTHY SUBJECTS
Poster Session C/Light Lunch (#711 – 933)
Jerome Barre1, Eric Lesauvage2, Carole Thang2, Brigitte Charron3,
Valerie Lameyre3
Franklin Hall B
1
Centre Hospitalier Intercommunal, Creteil, France, 2mediscis, Lagord,
France, 3sanofi-aventis, Paris, France
Franklin Hall B
Noon - 1:30 p.m.
711
REPRODUCTIVE TRACT INFECTIONS (RTI) IN FEMALE SLUM
POPULATION MUKURU, NAIROBI, KENYA
Marian Bartkovjak
Trnava University, Bratislava, Slovakia
717
A MULTINATIONAL, RANDOMIZED COMPARATIVE STUDY TO
ASSESS THE EFFICACY AND TOLERABILITY OF A FIXED DOSE
COMBINATION OF ARTESUNATE PLUS AMODIAQUINE ONCE
OR TWICE DAILY VERSUS A FIXED DOSE COMBINATION OF
ARTEMETHER PLUS LUMEFANTRINE FOR UNCOMPLICATED
Jean-Louis Ndiaye1, Babacar Faye1, Oumar Gaye1, Albert SameEkobo2, Vicky Ama-Moor2, Thomas Kuete2, Philippe Brasseur3,
Patrice Agnamey4, Milijoana Randrianarivelojosia5, Arsene
Ratsimbasoa5, Laurence Randrianasolo5, Issaka Sagara6, Aminata
Traore6, Yaya Dicko6, Brigitte Charron7, Valerie Lameyre7
1
University Cheikh Anta Diop, Dakar, Senegal, 2FMSB/CHU, Yaounde,
Cameroon, 3IRD, Dakar, Senegal, 4CHU, Amiens, France, 5institut Pasteur de
Madagascar, Antananarivo, Madagascar, 6MRTC, Bamako, Mali, 7SanofiAventis, Paris, France
164
718
www.astmh.org
724
DEPLOYMENT OF ARTEMETHER LUMEFANTRINE (AL) AT COMMUNITY LEVEL AND ITS IMPACT ON MALARIA SPECIFIC
DEATH RATE DURING AN EPIDEMIC YEAR
FETAL TOXOPLASMOSIS: OUTCOME AND MANAGEMENT OF
PREGNANCY IN 193 ROMANIAN FEMALE SURVEYS
A. Getachew1, A. Desta1, H. Lemma1, E. Fottrell2, Tigray Malaria
Study Group3
University of Medicine and Pharmacy, Bucharest, Romania
1
Tigray Health Bureau, Makale, Ethiopia, 2Department of Health and Clinical
Medicine, Umea University, Umea, Sweden, 3G. Barnabas, A. Bianchi, A.
Bosman, P. Byass, G. Costanzo, P. Ibarra de Palacios, N. Jude, A. Morrone, L.
Toma, Ethiopia
719
CLINICAL IMPACT OF ENHANCED AMPLIFIED
MYCOBACTERIUM TUBERCULOSIS DIRECT TEST (E-MTD) FOR
RAPID IDENTIFICATION OF MYCOBACTERIUM TUBERCULOSIS
ON RESPIRATORY SAMPLES
George M. Varghese, George Alangaden, Hussain Salimnia,
Tammy S. Lundstrom, P. H. Chandrasekar
Wayne State University, Detroit, MI, United States
720
Lidia E. Lazar
725
RIFT VALLEY FEVER IN A MALARIA EPIDEMIC-PRONE AREA,
IJARA DISTRICT, KENYA, JANUARY 2007
Francesco Grandesso1, Ole Wichmann2, Mercedes Tatay3, Northan
Hurtado3, Richard Lepec1, Vincent Brown1
1
Epicentre, Paris, France, 2German Field Epidemiology Training Programme,
Berlin, Germany, 3MSF, Paris, France
726
COMPLIANCE TO ARTESUNATE - AMODIAQUINE COMBINATION FOR THE TREATMENT OF UNCOMPLICATED MALARIA IN
THE MIDDLE BELT OF DISTRICT OF GHANA
Kwaku P. Asante1, Ruth Owusu-Ofori1, David K. Dosoo1, Seeba
Amengo-Eteego1, Elizabeth Awinie2, Seth Owusu-Agyei1
1
Kintampo Health Research Centre, Ghana Health Service, Brong Ahafo
Region, Ghana, 2Dodowa Health Research Centre, Ghana Health Service,
Greater Accra Region, Ghana
Jennifer R. Verani1, Gabriel A. Anthony2, Yao K. Sodahlon3,
Els Mathieu1
1
Ministry of Health, Lome, Togo, 3Mectizan Donation Program, Decatur, GA,
United States
2
721
THE U.S. EPA’S MULTIDISCIPLINARY APPROACH TO
EXAMINING THE LINKS BETWEEN BIODIVERSITY
AND HUMAN HEALTH
727
LONG LASTING HUMORAL AND CELLULAR RESPONSES TO
PLASMODIUM FALCIPARUM MEROZOITE SURFACE PROTEIN-1
IN THE LOW-TRANSMISSION AMAZON REGION OF PERU
CORRELATE WITH LONG-TERM CLINICAL PROTECTION
Eva Clark, Claudia J. Silva, Jean Hernandez, OraLee H. Branch
(ACMCIP Abstract)
728
Montira Pongsiri
U.S. Environmental Protection Agency, Washington, DC, United States
722
PREVALENCE OF BURULI ULCER CASES IN THE HEALTH DISTRICT OF AKONOLINGA, CAMEROON: A CROSS SECTIONAL
SURVEY USING CENTRIC SYSTEMATIC AREA SAMPLING
Klaudia Porten1, Karen Sailor2, Eric Comte3, Adelaide Njikap4,
Frank Doerner3, Agnes Sobry5, Francois Sihom6, Abanda Meya’a6,
Mark Myatt7, Sarah Eyangoh8, Rebecca Grais9
1
Epicentre, Geneva, Switzerland, 2MSF, Akonolinga, Switzerland, 3MSF,
Geneva, Switzerland, 4MSF, Akonolinga, Cameroon, 5MSF, Yaounde,
Cameroon, 6District de Santé, Akonolinga, Cameroon, 7Institute of
Ophthalmology, London, United Kingdom, 8Centre Pasteur, Yaounde,
Cameroon, 9Epicentre, Paris, France
723
THE EFFECTIVENESS OF AN OUTBREAK RESPONSE COURSE IN
THE AMERICAS
Juan Antonio Gálvez-Buccollini Abanto
SELF-EVALUATION OF VSS, A SYNDROMIC SURVEILLANCE
SYSTEM FOR OUTBREAK DETECTION IN PERU, A DEVELOPING
COUNTRY
Giselle Soto1, Carmen C. Mundaca1, Cesar V. Munayco2, Jose
Bolarte2, Roger V. Araujo-Castillo1, Luis Suarez-Ognio2, David
Blazes1
1
Naval Medical Research Center Detachment, Lima, Peru, 2Direccion General
de Epidemiologia, Lima, Peru
729
URBAN FARMING AND RISK FACTORS FOR SCHISTOSOMA
MANSONI, HOOKWORM AND MALARIA IN WESTERN CÔTE
D’IVOIRE
Barbara Matthys1, Eliézer K. N’Goran2, Penelope Vounatsou1,
Guéladio Cissé3, Andres B. Tschannen3, Marcel Tanner1,
Jürg Utzinger1
1
Swiss Tropical Institute, Basel, Switzerland, 2Université d’Abidjan-Cocody,
Abidjan, Cote d’Ivoire, 3Centre Suisse de Recherches Scientifiques, Abidjan,
Cote d’Ivoire
U.S. Naval Medical Research Center Detachment, Callao, Peru
165
INTEGRATION OF NEGLECTED DISEASE PROGRAMS IN TOGO:
EVALUATION OF A PILOT PROJECT
Detailed Program
www.astmh.org
730
INACTIVATION OF CHIKUNGUNYA VIRUS IN PLASMA AND
PLATELETS USING THE INTERCEPT BLOOD SYSTEM
L. Sawyer, A. Sampson-Johannes, J. Kinsey, K. Tsetsarkin, D. L.
Vanlandingham, S. Higgs
731
SAFETY AND EFFICACY OF SILYMARIN ON PATIENTS WITH
ACUTE HEPATITIS: A RANDOMIZED, CONTROLLED TRIAL
Samer El-Kamary1, Michelle Shardell1, Mohamed Metwally2,
Gamal Esmat3, Nabiel Mikhail4, Mohamed Hashem1, Mohamed
Abdelhamid5, G. Thomas Strickland1
1
Benha University, Benha, Egypt, 3Cairo University, Cairo, Egypt, 4Assiut
University, Assiut, Egypt, 5Minia University, Minia, Egypt
2
732
DROUGHT WAS A CONSTANT FACTOR IN THE INITIATION OF
LARGE EPIDEMICS OF LOUSE-BORNE TYPHUS
736
MALARIA INFECTION AND ANEMIA AMONG PREGNANT
WOMEN AND CHILDREN UNDER FIVE YEARS OF AGE: A
PREVALENCE SURVEY FROM FIVE DISTRICTS IN EASTERN
INDONESIA
Maria E. Sumiwi1, Andrew Auld1, Jodi van den Eng2, Endang
Widyastuti3, Ferdinand J. Laihad4, Hanifah Rogayah4, Charles
Tobing4, William A. Hawley1, William A. Hawley2
1
United Nations Children’s Fund, Jakarta, Indonesia, 2Centers for Disease
Control and Prevention, Atlanta, GA, United States, 3CARE, Jakarta,
Indonesia, 4Sub Directorate Malaria, Ministry of Health, Jakarta, Indonesia
737
ACHIEVING EFFECTIVE COVERAGE: THE IMPORTANCE OF
QUALITY AND USE CONSIDERATIONS IN SCALING UP BED NET
DISTRIBUTION PROGRAMS FOR MALARIA CONTROL AND
PREVENTION
Carol A. Medlin1, Carol Kolb2
1
Institute for Global Health, San Francisco, CA, United States, 2University of
Rodolfo Acuna-Soto1, David W. Stahle2, Matthew D. Therrell3,
Jose Villanueva Diaz4
738
1
Universidad Nacional Autonoma de Mexico, Ciudad de Mexico, Mexico,
2
Department of Geosciences, University of Arkansas, Fayetteville, AR, United
States, 3Department of Environmental Sciences, University of Virginia,
Charlottesville, VA, United States, 4Instituto Nacional de Investigaciones
Forestales Agricolas y Pecuarias, Gomez Palacio, Durango, Mexico
733
ASSESSMENT OF CLINICAL TROPICAL MEDICINE COMPETENCY
AMONG U.S.-TRAINED MEDICAL STUDENTS AND RESIDENTS
Lipi Roy, Latha Rajan
734
REDUCED PEDIATRIC HOSPITALIZATIONS FOR SEVERE
MALARIA FOLLOWING IMPLEMENTATION OF COMMUNITYBASED PREVENTION AND EARLY TREATMENT PROGRAMS IN
RURAL RWANDA
Amy Sievers1, Jennifer Lewey2, Blaise Bucyibaruta3, Placide
Musafiri3, Corine Karema4, Johanna Daily1
ASSOCIATED INFECTIONS TO HUMAN BARTONELLOSIS
(ACUTE CARRION’S DISEASE) INPATIENTS IN AN ENDEMIC
AREA OF THE NORTHERN FOREST OF PERU
Paul E. Pachas1, Miguel Aranda2, Lucinda Troyes3, David Matos2,
Zoila Villegas3, Nelson Solorzano4, Yanina Rojas2, Jose Arias2, Carlos
Padilla5, Gladys Ventura5, Alexander Canelo3, Jorge A. Chancafe6,
Luis A. Suarez-Ognio1
1
General Directorate of Epidemiology - Ministry of Health Peru, Lima, Peru,
Jaen General Hospital, Cajamarca Department, Peru, 3Jaen Directorate of
Health, Cajamarca Department, Peru, 4Caraz Hospital, Ancash Department,
Peru, 5National Institute of Health, Lima, Peru, 6San Ignacio Health Center,
Cajamarca Department, Peru
2
739
ADIPONECTIN AND LEPTIN - YIN AND YANG MEDIATORS OF
THE MACROPHAGE INFLAMMATORY RESPONSE, DEPENDENT
ON HOST NUTRITIONAL STATUS
Gregory M. Anstead, Qiong Zhang, Peter C. Melby
South Texas Veterans Healthcare System, San Antonio, TX, United States
1
Brigham and Women’s Hospital, Boston, MA, United States, 2Harvard
Medical School, Boston, MA, United States, 3Rwinkwavu Hospital/Partners in
Health, Rwinkwavu, Rwanda, 4Programme National Integre de Lutte contre
le Paludisme, Kigali, Rwanda
735
PROSPECTIVE ASSESSMENT OF SEVERE MALARIA FOR
CLINICAL TRIALS AT INSTITUTIONS IN WESTERN KENYA
Shon A. Remich1, Walter Otieno2, Duke Omariba2, Mark
Polhemus3, Berhnards Ogutu4, Doug Walsh5, Robert Miller6
1
Walter Reed Army Medical Center, Washington, DC, United States, 2Kenya
Medical Research Institute, Kisumu, Kenya, 3United States Army Medical
Unit - Kenya, Kisumu, Kenya, 4Kemri Medical Research Institute, Kisumu,
Kenya, 5United States Army Medical Research Unit-Kenya, Kisumu, Kenya,
6
Walter Reed Army Institute of Research, Washington, DC, United States
Diarrhea
740
ETIOLOGY OF DIARRHEA AMONG 0- TO 59-MONTH OLD
CHILDREN IN BAMAKO, MALI - A PILOT STUDY
Mama N. Doumbia1, Boubou Tamboura1, Milagritos D. Tapia2,
Mariam Sylla3, Mamadou M. Keita3, Samba O. Sow1, Myron M.
Levine2, Karen L. Kotloff2
1
3
Hopital Gabriel Toure, Bamako, Mali
2
166
741
www.astmh.org
747
EMERGENCE AND CLONAL EXPANSION OF INTESTINAL
QUINOLONE-RESISTANT ESCHERICHIA COLI IN SOUTHWESTERN NIGERIA
THE EFFECT OF PREPARATION OF CEBICHE ON THE SURVIVAL
OF ESCHERICHIA COLI, AEROMONAS HYDROPHILA AND
VIBRIO PARAHEMOLYTICUS
Rebeccah S. Lijek1, Rima Bishar1, Adebayo Lamikanra2, John
Wain3, Iruka N. Okeke1
Andres Herrera Camino, Benjamin J. Espinosa, Gladys Nunez,
Nereyda Espinoza Zegarra, Gregory J. Martin
1
Haverford College, Haverford, PA, United States, 2Obafemi Awolowo
University, Ile-Ife, Nigeria, 3Wellcome Trust Genome Institute, Cambridge,
United Kingdom
U.S. Naval Medical Research Center Detachment Peru, Lima, Peru
742
CHARACTERISTICS OF CHOLERA OUTBREAK IN DELHI
(2000-2006)
Vineet Gupta1, Tripurari Kumar2, Sanjeev Bhoi1
1
All India Institute of Medical Sciences, New Delhi, India, 2Department of
Health, Municipal Corporation Delhi, New Delhi, India
743
ELECTROLYTE AND MIXED ACID-BASE DISTURBANCES IN
CHOLERA
Katayoun Vahdat1, Mehrnaz Resoulinejat2
1
Professor Haghighi Department of Tropical Medicine, The Persian Gulf
Health Research Center/Bushehr University of Medical Sciences, Bushehr,
Islamic Republic of Iran, 2Department of Infectious Diseases, Tehran
University of Medical Sciences, Tehran, Islamic Republic of Iran
748
THE RETINOL EFFECT IN PROTECTING THE INTESTINAL EPITHELIAL DAMAGE INDUCED BY CLOSTRIDIUM DIFFICILE TOXIN A
Andressa A. Maciel1, Reinaldo B. Oria1, Manuel B. Braga-Neto1,
Gerly A. Brito2, Ibraim C. Castro1, Eunice B, Carvalho1, Herene B.
Lucena1, Aldo A. Lima1, Richard L. Guerrant3
1
Clinic Research Unit and Institute of Biomedicine, School of Medicine,
Federal University of Ceara, Fortaleza-CE, Brazil, 2Department of
Pharmacology, School of Medicine, Federal University of Ceara, Fortaleza-CE,
Brazil, 3Center for Global Health, School of Medicine, University of Virginia,
Charlottesvlile, VA, United States
749
HAND WASHING AND WATER USAGE IN A
PERUVIAN SHANTYTOWN
William E. Oswald1, Gabrielle C. Hunter1, Andres G. Lescano2,
Lilia Cabrera3, Maritza C. Calderon2, Robert H. Gilman1
1
PREVALENCE OF DIARRHEAGENIC E. COLI AMONG BACTERIAL
ISOLATES IN PATIENTS WITH ACUTE DIARRHEA IN
UZBEKISTAN: THREE YEARS SURVEILLANCE PROJECT RESULTS
Gulnara A. Ibadova1, Aybek V. Khodiev1, Tamara S. Nechmireva1,
Gulnara K. Abdukhalilova1, Ruslan S. Madyarov1, Carl J. Mason2,
Ladaporn Bodhidatta2
1
Scientific Research Institute of Epidemiology, Microbiology and Infectious
Diseases, Tashkent, Uzbekistan, 2Armed Force Research Institute of Medical
Sciences, Bangkok, Thailand
745
States, 2Universidad Peruana Cayetano Heredia, Lima, Peru, 3Asociación
Benéfica PRISMA, Lima, Peru
750
SURVEILLANCE FOR ACUTE DIARRHEAL DISEASES AMONG
PERUVIAN MILITARY RECRUITS AT THE VARGAS-GUERRA
ARMY (VGE) BASE IN IQUITOS, PERU: FEBRUARY 2004FEBRUARY 2007
Giovanna Pastor1, Rosa Burga1, Franca Jones2, Juan Perez1, Rina
Meza1, Maruja Bernal1, Yocelinda Meza1, Benjamin Espinosa1,
Robert Kaminski3, Edwin Oaks3, Eric R. Hall1
1
Naval Medical Research Center-Detachment, U.S. Embassy - Lima, Peru,
Naval Medical Research Center, Silver Spring, MD, United States, 3Walter
2
CRYPTOSPORIDIUM AND MALNUTRITION ADDITIVELY
INCREASE ILEAL DAMAGE AND PRO-INFLAMMATORY
CYTOKINE RESPONSES
Bruna P. Coutinho1, Carlos M. Vieira1, Cirle A. Warren2, Jesus
Emmanuel A. Sevilleja2, Jamilly G. Maciel1, João R. Brito1, Aldo A.
Lima1, Reinaldo B. Oria1, Richard L. Guerrant2
1
Federal University of Ceara, Fortaleza-CE, Brazil, 2Center for Global Health,
School of Medicine, University of Virginia, Charlottesville, VA, United States
746
ROTAVIRUS DIARRHEA IN GHANA: EMERGING IMPORTANCE
OF ZOONOTIC STRAINS
751
DETECTION OF A HIGHLY SENSITIVE HUMAN FECAL
BIOMARKER (10-10) IN ≤ 10 ML CONTAMINATED DRINKING
WATER SAMPLES USING IMMUNOMAGNETIC SEPARATION
Jesus Emmanuel A. Sevilleja1, Curtis C. Copeland2,
Richard L. Guerrant2
1
Center for Global Health, University of Virginia/National Institutes of Health,
University of the Philippines, Charlottesville, VA, United States, 2Center for
Global Health, University of Virginia, Charlottesville, VA, United States
Richard H. Asmah1, George E. Armah2, Fred N. Binka3,
Francis Anto4
1
School of Allied Health, Accra, Ghana, 2Noguchi Memorial Institute for
Medical Research, Legon, Ghana, 3School of Public Health, Accra, Ghana,
4
Navrongo Health Research Center, Navrongo, Ghana
167
744
Detailed Program
www.astmh.org
752
GLUTAMINE AND ZINC SUPPORT BRAIN DEVELOPMENT IN
SUCKLING SWISS MICE CHALLENGED BY UNDERNUTRITION
Ibraim C. Castro1, Bruna P. Coutinho1, Bruna B. Oliveira1, Fernando
V. Ladd2, Aliny B. Ladd2, George André F. Sales1, Antônio Augusto
C. Ribeiro2, Aldo A. Lima1, Reinaldo B. Oria1, Richard L. Guerrant3
1
Federal University of Ceara, Fortaleza-CE, Brazil, 2Laboratory of Stereology
and Chemical Anatomy, College of Veterinarian Medicine, University of Sao
Paulo, Sao Paulo-SP, Brazil, 3Center for Global Health, School of Medicine,
753
APOE KNOCK-OUT MICE HAVE DISRUPTED INTESTINAL TIGHT
JUNCTIONS, FOLLOWING EARLY POST-NATAL MALNUTRITION
Reinaldo B. Oria1, Bruna Coutinho1, Manuel B. Braga-Neto1, Isa
Hussaini2, Maria Beatriz Lopes2, Weibin Shi3, Aldo A. Lima1, Richard
L. Guerrant4
1
Federal University of Ceara, Fortaleza-CE, Brazil, 2Department of Pathology,
School of Medicine, University of Virginia, Charlottesville, VA, United States,
3
Department of Radiology, School of Medicine, University of Virginia,
Charlottesville, VA, United States, 4Center for Global Health, School of
Medicine, University of Virginia, Charlottesville, VA, United States
754
DENGUE VIRUS SEROTYPE 2 (SE ASIAN STRAIN) IS STRONGLY
ASSOCIATED WITH CLINICALLY DEFINED SECONDARY INFECTIONS IN PUERTO RICO
Gilberto A. Santiago, Iris Sosa, Candimar Colon, Jorge MuñozJordán
755
GENETIC CHARACTERIZATION OF DENGUE 3 VIRUS ISOLATES
RECOVERED FROM PATIENTS WITH ENCEPHALOMYELITIS,
RONDÔNIA STATE, NORTHERN BRAZIL
Márcio R. Nunes, Samir M. Casseb, Helena B. Vasconcelos, Eliana V.
da Silva, Pedro F. Vasconcelos
Instituto Evandro Chagas, Belém, Brazil
756
EVALUATION OF A COMMERCIAL NS-1 ANTIGEN CAPTURE
ELISA FOR THE DIAGNOSIS OF ACUTE DENGUE INFECTION
Kovi Bessoff, Manuela Beltran, Edgardo Vergne,
Elizabeth Hunsperger
Centers for Disease Control and Prevention, Division of Vector Borne
Infectious Diseases, Dengue Branch, San Juan, PR, United States
757
A BIVALENT DNA VACCINE CANDIDATE AGAINST DENGUE-3
AND DENGUE-4 EXPRESSING THE STRUCTURAL PRM/E
PROTEINS ELICITS CELLULAR IMMUNE RESPONSE AND
PROTECTS MICE AGAINST LETHAL CHALLENGE
Danielle M. Lima1, Sérgio O. De Paula2, Patricia V. Palma1,
Benedito A. Fonseca1
1
School of Medicine of Ribeirão Preto, Ribeirão Preto, S.P., Brazil, 2Federal
University of Viçosa, Viçosa, M.G., Brazil
758
SERUM LEVELS OF TNF-ALPHA, IL-6 AND IFN-GAMMA
AMONG TWO ETHNIC GROUPS INFECTED WITH
DENGUE IN COLOMBIA
Berta N. Restrepo1, Ruth E. Ramirez1, Margarita Arboleda1,
Marco Restrepo1, Marta Ospina2
1
Instituto Colombiano de Medicina Tropical-Universidad CES, Sabaneta,
Colombia, 2Direccion Seccional de Salud de Antioquia, Medellin, Colombia
759
DIFFERENTIAL EXPRESSION OF EFFECTOR-MEMORY CD8+T
CELL SUBSETS IN PERIPHERAL BLOOD CORRELATES WITH
DENGUE HEMORRHAGIC FEVER
Beatriz Parra, Gerardo A. Libreros, Edwin H. Pardo, Graciela
Rengifo, Anilza Bonelo, Fabián Méndez
Universidad del Valle, Cali, Colombia
760
SEROTYPE-SPECIFIC CLINICAL CHARACTERISTICS OF HOSPITALIZED DENGUE IN THE PHILIPPINES
John Mark S. Velasco1, Maria Theresa Alera2, Charity A. YpilButac1, Mammen P. Mammen3, Robert V. Gibbons3, Richard
Jarman3, Ananda Nisalak3, In-Kyu Yoon3
1
Armed Forces Research Institute of Medical Sciences-Philippines, Manila,
Philippines, 2San Lazaro Hospital, Manila, Philippines, 3Armed Forces
Research Institute of Medical Sciences, Bangkok, Thailand
761
HEAVY PRECIPITATION IN THE BEGINNING OF THE SUMMER IS
ASSOCIATED TO A SMALLER NUMBER OF DENGUE CASES IN
RIBEIRÃO PRETO, SÃO PAULO STATE, BRAZIL
Paula Takahashi, Benedito A. Fonseca
School of Medicine of Ribeirão Preto, Ribeirão Preto, S.P., Brazil
762
THE ROLE OF T CELLS IN DENGUE VIRUS INFECTION
Lauren E. Yauch, Sujan Shresta
168
763
767
2
1
Robert Gibbons , Siripen Kalanarooj , Richard Jarman , Ananda
Nisalak1, David Vaughn3, Timothy Endy4, Mammen Mammen5,
Anon Srikiatkhachorn6
1
Armed Forces Research Institute for Medical Sciences, Bangkok, Thailand,
2
Queen Sirikit Institute for Child Health, Bangkok, Thailand,
3
GlaxoSmithKline, King of Prussia, PA, United States, 4State University of
New York, Syracuse, NY, United States, 5United States Army Medical
Research and Materiel Command, Fort Detrick, MD, United States,
6
764
UTILIZATION OF MEDICAL SERVICES AND QUALITY OF LIFE
AMONG DENGUE PATIENTS IN EIGHT ENDEMIC COUNTRIES
Donald S. Shepard1, Jose A. Suaya1, Blas Armien2, Mariana
Caram1, Leticia Castillo3, Ngan Chantha4, Fàtima Garrido5,
Sukhontha Kongsin6, Lucy Lum7, Romeo H. Montoya8, João B.
Siqueira9, Rana Sughayyar1, Karen Tyo1
1
Brandeis University, Waltham, MA, United States, 2Instituto Conmemorativo
Gorgas de Estudios de la Salud, Panama City, Panama, 3National Health
Laboratory, Ministry of Health and Social Assistance, Guatemala City,
Guatemala, 4National Dengue Control Program at the National Center for
Malaria, Ministry of Health, Phnom Penh, Cambodia, 5Ministry of Health
and Social Development, Caracas, Venezuela, 6Mahidol University, Bangkok,
Thailand, 7University of Malaya Medical Center, Kuala Lumpur, Malaysia,
8
Ministry of Health and Social Assistance, San Salvador, El Salvador, 9Federal
University of Goiás, Goiana, Brazil
765
ANALYSIS OF NS-1 ANTIGEN AND VIREMIA IN HOSPITALIZED
DENGUE HEMORRHAGIC FEVER AND DENGUE FEVER
PATIENTS IN THAILAND
1
1
Rick G. Jarman , Chonticha Klungthong , Butsaya
Thaisomboonsuk1, Ananda Nisalak1, Alan Rothman3, Sharone
Green3, Stephen Thomas3, Jean Francois Toussaint4, Siripen
Kalanarooj5, Robert Gibbons1
SEQUENCE OF INFECTION RATES DETERMINED USING SINGLE
DILUTION NEUTRALIZATION ASSAY FROM 1998-2001
KAMPHAENG PHET THAILAND PROSPECTIVE STUDY
Ananda Nisalak1, Scott B. Halstead2, Timothy Endy3, Butsaya
Thaisomboonsuk1, Alan Rothman4, Sharone Green4, Robert
Gibbons1, Richard G. Jarman1
1
Supportive R&D, Pediatric Dengue Vaccine Initiative, Bethesda, MD, United
States, 3State University of New York, Syracuse, NY, United States,
4
2
768
ESTIMATING THE TOTAL WORLD POPULATION AT RISK FOR
LOCALLY ACQUIRED DENGUE INFECTION
Mark E. Beatty, William Letson, Dianna M. Edgil, Harold S.
Margolis
International Vaccine Institute, Seoul, Republic of Korea
769
CLIMATE-BASED FORCASTING MODELS FOR DENGUE: A CASE
STUDY IN PRACHUAP KHIRI KHAN PROVINCE IN THAILAND
Mathuros Tipayamongkholgul
Graduate Institute of Epidemiology, Taipei, Taiwan
Helminths – Nematodes – Filariasis (Clinical)
770
AFTER A DECADE OF ANNUAL DOSE OF IVERMECTIN ON
ONCHOCERCIASIS PREVALENCE IN CAMEROON AND UGANDA, TRANSMISSION CONTINUES
Moses N. Katabarwa1, Peace Habomugisha2, Tom Lakwo3, Albert
Eyamba4, Frank O. Richards1
1
The Carter Center, Atlanta, GA, United States, 2The Carter Center, Kampala,
Uganda, 3Ministry of Health, Kampala, Uganda, 4The Carter Center,
Yaoundé, Cameroon
Helminths - Nematodes - Filariasis (Epidemiology)
1
Armed Forces Research Institute for Medical Sciences, Bangkok, United
States, 2University of Massachusetts Medical School, Worcester, MA, United
States, 3Walter Reed Army Institute of Research, Silver Spring, MD, United
States, 4GlaxoSmithKline, Rixensart, Belgium, 5Queen Sirikit Institute for
Child Health, Bangkok, Thailand
766
CLINICAL DESCRIPTION OF DENGUE FEVER AND DENGUE
HEMORRHAGIC FEVER CASES IDENTIFIED DURING A CLUSTER
EPIDEMIOLOGY STUDY IN WEST JAVA, INDONESIA
Herman Kosasih1, Kiki M. Samsi2, Bachti Alisjahbana3, Zen Hafy1,
Djoko Yuwono4, Nurhayati1, Panji F. Hadisoemarto3, Patrick Blair1,
Timothy Burgess1
1
Naval Medical Research Unit 2, Jakarta, Indonesia, 2Sumber Waras Hospital,
Jakarta, Indonesia, 3Hasan Sadikin Hospital, Bandung, Indonesia, 4National
Institute of Health Research and Development, Jakarta, Indonesia
771
EVALUATION OF WHOLE BLOOD COLLECTION METHODS
USING THE OG4C3 ELISA IN BANCROFTIAN FILARIASIS
David Reeve, Wayne Melrose, Jan Smith, Jennifer Elliman
James Cook University, Townsville, Australia
772
DENSITY-DEPENDENT MORTALITY OF THE HUMAN HOST IN
ONCHOCERCIASIS: RELATIONSHIPS BETWEEN MICROFILARIAL
LOAD AND EXCESS MORTALITY
Mark P. Little1, Karen Wagner2, Edoh William Soumbey-Alley3,
Maria-Gloria Basáñez1
1
Imperial College London, London, United Kingdom, 2Health Protection
Agency, London, United Kingdom, 3World Health Organization Regional
Office for Africa, Brazzaville, Congo
169
AN ANALYSIS OF REPEAT HOSPITAL ADMISSIONS FOR
DENGUE TO ESTIMATE THE FREQUENCY OF THIRD OR
FOURTH DENGUE INFECTIONS RESULTING IN ADMISSIONS,
DENGUE HEMORRHAGIC FEVER, AND SEROTYPE SEQUENCES
1
www.astmh.org
Detailed Program
www.astmh.org
773
EFFECT OF SINGLE DOSE IVERMECTIN ON ONCHOCERCA
VOLVULUS: A SYSTEMATIC REVIEW
Maria-Gloria Basáñez1, Sébastien D.S. Pion2, Eve Boakes1, João
A.N. Filipe3, Thomas S. Churcher1, Michel Boussinesq4
1
Imperial College London, London, United Kingdom, 2Institut
d’Epidémiologie et de Neurologie Tropicale, Limoges, France, 3London
School of Hygiene and Tropical Medicine, London, United Kingdom, 4Institut
de Recherche pour le Développement, Paris, France
774
778
WHOLE GENOME AMPLIFICATION AND OLIGONUCLEOTIDE
ARRAY HYBRIDIZATION FOR GENOMIC CHARACTERIZATION
OF FILARIAL PARASITES
Samantha N. Piper
779
LONG-TERM DOXYCYCLINE TREATMENT AFFECTS
WOLBACHIA AND PARASITE GENE EXPRESSION IN ADULT
FEMALE BRUGIA MALAYI
FIVE YEARS OF MDA FOR FILARIASIS: REFLECTIONS
ON THE SUCCESSES, CHALLENGES AND ASPECTS OF
PROGRAM INTEGRATION
Ramakrishna U. Rao1, Yeufang Huang1, Seth D. Crosby2,
Makedonka Mitreva2, Yong Yin2, Gary J. Weil1
Charles Mackenzie1, Mwele Malecela2, Esther Mwakitalu2
2
1
Michigan State University, Dimondale, MI, United States, 2NIMR, Dar es
Salaam, United Republic of Tanzania
Helminths - Nematodes - Filariasis (Immunology)
775
DEVELOPMENT OF A RAPID FLOW CYTOMETRIC ASSAY FOR
THE MEASUREMENT OF MURINE BASOPHIL ACTIVATION
Marina N. Torrero, Edward Mitre
States
(ACMCIP Abstract)
Helminths - Nematodes - Filariasis (Molecular Biology)
776
P-GLYCOPROTEIN-LIKE PROTEIN, A PROMISING GENETIC
MARKER TO FOLLOW POTENTIAL IVERMECTIN RESISTANCE IN
ONCHOCERCA VOLVULUS
Catherine Bourguinat1, Bernadette F. Ardelli2, Sebastien D. Pion3,
Joseph Kamgno4, Jacques Gardon5, Brian O. Duke6, Michel
Boussinesq7, Roger K. Prichard1
1
Institute of Parasitology, McGill University, Sainte-Anne-de-Bellevue, QC,
Canada, 2Department of Zoology, Brandon University, Brandon, MB,
Canada, 3Laboratoire de Neuroparasitologie et Neuroépidémiologie
Tropicale, Faculté de Médecine, Limoges, France, 4National Onchocerciasis
Task Force Cameroon, Yaounde, Cameroon, 5UR 24 Epidémiologie et
Prévention, Institut de Recherche pour le Développement, La Paz, Bolivia,
6
River Blindness Foundation, Lancaster, United Kingdom, 7UR 24
Epidémiologie et Prévention, Institut de Recherche pour le Développement,
Paris, France
777
GENE EXPRESSION AND LOCALIZATION STUDIES OF THE
FILARIAL DIAGNOSTIC ANTIGEN BM14
Daojun Jiang, Peter U. Fischer, Amy C. Rush, Ben-Wen Li, Kurt C.
Curtis, Ramakrishna U. Rao, Gary J. Weil
Infectious Diseases Division, Washington University School of Medicine, St.
Louis, MO, United States
1
Washington University School of Medicine, St. Louis, MO, United States,
Genome Sequencing Center, Washington University School of Medicine, St.
Louis, MO, United States
780
ANNOTATION AND FUNCTIONAL ANALYSIS OF GENDER-REGULATED GENE EXPRESSION IN ADULT BRUGIA MALAYI
Ben-Wen Li
Washington University School of Medicine, St Louis, MO, United States
(ACMCIP Abstract)
782
THE WOLBACHIA ENDOSYMBIONT OF FILARIAL PARASITES
CONTAIN HEME BIOSYNTHESIS ENZYMES WHICH ARE POTENTIAL DRUG TARGETS
Bo Wu, Beth Ann Cantin, Barton Slatko
New England Biolabs, Inc., Ipswich, MA, United States
Helminths - Nematodes - Filariasis (Other)
783
ULTRASTRUCTURAL STUDY OF BRUGIA PAHANGI: A RICH
ANTIGENIC SOURCE
Kajee Pilakasiri1, Chaiyaphruk Pilakasiri2, Jantima
Roongruangchai1, Kosol Roonrruangchai3, Prasert Sobhon4
1
Department of Anatomy, Faculty of Medicine Siriraj Hospital, Bangkok,
Thailand, 2Armed Forces Research Institute of Medical Sciences, Bangkok,
Thailand, 3Department of Parasitology, Faculty of Medicine Siriraj Hospital,
Bangkok, Thailand, 4Department of Anatomy, Faculty of Science, Mahidol
University, Bangkok, Thailand
784
A RANDOMIZED DOUBLE-BLIND CONTROL TRIAL OF A SINGLE
DOSE OF DIETHYLCARBAMAZINE IN COMBINATION WITH
DOXYCYCLINE FOR TREATMENT OF WUCHERERIA BANCROFTI
INFECTION
Vivornpun Sanprasert1, Anupong Sujariyakul2, Kanitha
Patarakul3, Surang Nuchprayoon1
1
Lymphatic Filariasis Research Unit, Department of Parasitology, Faculty of
Medicine, Chulalongkorn University, Bangkok, Thailand, 2Office of Disease
Prevention and Control Nakhon Sawan Province, Thailand, 3Department of
Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok,
Thailand
170
785
788
VARIANT SNPS OF THE IL-10 PROMOTER AT POSITIONS
-854 AND -627 RESPONSIBLE FOR LOW IL-10 SECRETION
ARE ASSOCIATED WITH LOWER LEVELS OF CIRCULATING
BRUGIA TIMORI MICROFILARIAE BUT NOT WITH
FILARIAL LYMPHEDEMA
2
1
AN EPIDEMIOLOGICAL SURVEY FOR HUMAN AND CANINE
LEISHMANIASIS IN AYDIN PROVINCE, TURKEY
Sema Ertug1, Pinar Okyay2, Tülin Karagenc3, Hasan Eren3, Hatice
Ertabaklar1, Yusuf Ozbel4
1
3
Kenneth Pfarr , Peter Fischer , Sandra Arriens , Jessica Douglas ,
Bertram Müller-Myhsok4, Kerstin Fischer2, Christian Timmann5,
Taniawati Supali6, Achim Hoerauf1
1
University Clinic Bonn, Bonn, Germany, 2Washington University School of
Medicine, St. Louis, MO, United States, 3University of Glasgow, Glasgow,
United Kingdom, 4Max Planck Institute of Psychiatry, Munich, Germany,
5
Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany,
6
University of Indonesia, Jakarta, Indonesia
(ACMCIP Abstract)
Kinetoplastida - Epidemiology
786
IDENTIFYING TRYPANOSOMA CRUZI INFECTION IN CHILDREN
DURING A VECTOR CONTROL CAMPAIGN
Michael Z. Levy1, Vivian Kawai2, Natalie M. Bowman2, Lance A.
Waller1, Lilia Cabrera2, Viviana V. Pinedo-Cancino2, Amy E. Seitz1,
Frank J. Steurer3, Juan G. Cornejo del Carpio4, Eleazar CordovaBenzaquen5, James H. Maguire6, Robert H. Gilman7, Caryn Bern3
1
Emory University, Atlanta, GA, United States, 2AB Prisma, Lima,
Peru, 3Division of Parasitic Diseases, Centers for Disease Control and
Prevention, Atlanta, GA, United States, 4Dirección Regional del
Ministerio de Salud, Arequipa, Peru, 5AB Prisma, Arequipa, Peru,
6
University of Maryland, Baltimore, MD, United States, 7Bloomberg
School of Public Health, Johns Hopkins University, Baltimore, MD,
United States
Adnan Menderes University Medical Faculty Department of Parasitology,
Aydin, Turkey, 2Adnan Menderes University Medical Faculty, Department of
Public Health, Aydin, Turkey, 3Adnan Menderes University Veterinary Faculty,
Department of Parasitology, Aydin, Turkey, 4Ege University Medical Faculty,
Department of Parasitology, Aydin, Turkey
789
SINGLE STRAND CONFORMATION POLYMORPHISM AND
INFECTION IN MICE OF VISCERAL LEISHMANIASIS ISOLATED
FROM NEPALESE PATIENTS
Kishor Pandey1, Tetsuo Yanagi1, Basu Dev Pandey2, Arun Kumar
Mallik3, Jeevan Bahadur Sherchand4, Hiroji Kanbara1
1
Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan,
Sukraraj Tropical and Infectious Disease Hospital, Kathmandu, Nepal,
3
Janakpur Zonal Hospital, Janakpur, Nepal, 4Department of MicrobiologyParasitology, Tribhuvan University Teaching Hospital, Kathmandu, Nepal
2
(ACMCIP Abstract)
790
EPIDEMY OF CUTANEOUS LEISHMANIASIS IN
OUAGADOUGOU, BURKINA FASO (WEST AFRICA): INVESTIGATIONS ON THE VECTORS AND THE RODENT RESERVOIR OF
THE PARASITES
Robert T. Guiguemde
Centre Muraz, Bobo-Dioulasso, Burkina Faso
791
787
MULTI-SITE EPIDEMIOLOGIC STUDIES OF CHAGAS’
DISEASE IN PREGNANT WOMEN FROM THREE LATIN
AMERICAN COUNTRIES
Sergio Sosa-Estani1, Pierre Buekens1, Jackeline Alger2, Olivia
Almendares1, Fernando Althabe3, Domingo Amador4, José Belizán3,
Eduardo Bergel3, María Luisa Cafferata5, Jaime Del Cid4, Eric
Dumontiel6, Rubí Gamboa-Leon6, Luis Israel Giron7, Mark James1,
Nicolas Padilla-Raygoza8, Carlos Ponce9, Elisa Ponce9, Concepción
Zúniga10
1
Orleans, LA, United States, 2Servicio de Parasitologia, Hospital Escuela,
Tegucigalpa, Honduras, 3Institute for Clinical Effectiveness and Health Policy,
Buenos Aires, Argentina, 4Hospital Enrique Aguilar Cerrato, La Esperanza,
Intibuca, Honduras, 5Perinatal Research Unit, Montevideo, Uruguay,
6
Universidad Atónoma de Yucatán, Mérida, Mexico, 7Region Departamental
de Salud, La Esperanza, Intibuca, Honduras, 8Facultad de Enfermería y
Obstetricia de Celaya, Universidad de Guanajuato, Celaya, Mexico, 9Sección
Chagas Leishmaniasis, División Laboratorio Central, Ministerio de Salud
Pública, Tegucigalpa, Honduras, 10Ministerio de Salud Pública, Tegucigalpa,
Honduras
IS PHLEBOTOMUS HALEPENSIS NATURAL VECTOR OF
LEISHMANIA TROPICA? A PARASITOLOGICAL SURVEY IN A
NEW CUTANEOUS LEISHMANIASIS FOCUS IN CENTRAL
ANATOLIA OF TURKEY
Yusuf Ozbel1, Cuneyt Balcioglu2, Seray Ozensoy Toz1, Gulden
Sonmez3, Samiye Demir4, Hatice Ertabaklar5
1
Ege University Medical School, Izmir, Turkey, 2Celal Bayar University Medical
School, Manisa, Turkey, 3Kocaeli University Medical School, Kocaeli, Turkey,
4
Ege University Science School, Izmir, Turkey, 5Adnan Menderes University
Medical School, Izmir, Turkey
792
IMMUNO-EPIDEMIOLOGY OF VISCERAL LEISHMANIASIS IN A
COHORT OF BRAZILIAN DOGS
Seyi Soremekun1, Rupert Quinnell2, Lourdes Garcez3, Paul Bates4,
Matthew Rogers5, Orin Courtenay1
1
University of Warwick, Coventry, United Kingdom, 2University of Leeds,
Leeds, United Kingdom, 3Instituto Evandro Chagas, Belem, Brazil, 4Liverpool
School of Tropical Medicine, Liverpool, United Kingdom, 5London School of
Hygiene and Tropical Medicine, London, United Kingdom
(ACMCIP Abstract)
171
1
www.astmh.org
Detailed Program
www.astmh.org
793
800
ACUTE CHAGAS DISEASE OUTBREAK ASSOCIATED TO AÇAÍ
JUICE CONSUMPITION - PARÁ STATE/BRAZIL, 2006
DEVELOPMENT OF A MOUSE MODEL FOR PREGNANCYASSOCIATED MALARIA STUDIES
Aglaêr A. da Nóbrega
Claudio R. Marinho, Rita Neres, Carlos Penha-Gonçalves
Field Epidemiology Training Program, Secretariat of Health Surveillance,
Ministry of Health (MoH), Brasilia, Brazil
Instituto Gulbenkian de Ciência, Oeiras, Portugal
(ACMCIP Abstract)
794
801
IMPACT OF HUMAN AFRICAN TRYPANOSOMIASIS IN A RURAL
COMMUNITY IN DEMOCRATIC REPUBLIC OF CONGO
Pascal Lutumba1, Eric Makieya2, Alexandra Shaw3, Filip Meheus4,
Marleen Boelaert1
1
Institute of Tropical Medicine, Antwerp, Belgium, 2Kinshasa University,
Kinshasa, Democratic Republic of the Congo, 3AP Consultant, Andover,
United Kingdom, 4Royal Tropical Institute, Amsterdam, Netherlands Antilles
PLASMODIUM YOELII MAKES A FUNCTIONAL HOMOLOG OF
THE MAMMALIAN MACROPHAGE MIGRATION INHIBITORY
FACTOR
Swati Thorat
(ACMCIP Abstract)
802
796
IMPACT OF CLIMATE VARIABILITY ON CUTANEOUS
LEISHMANIASIS IN VENEZUELA
Alfonso J. Rodriguez-Morales1, Liliana Rada2, Jesus Benitez3,
Carlos Franco-Paredes4
1
2
Universidad de Los Andes, Trujillo, Venezuela, Salud Miranda, Miranda,
Venezuela, 3Ministry of Health, Maracay, Venezuela, 4Emory University,
GENE EXPRESSION ANALYSIS OF ENDOTHELIAL CELL ADHERENT VERSUS NON-ADHERENT RETICULOCYTES INFECTED
WITH PLASMODIUM YOELII 17X
Amy Cernetich-Ott, Thomas M. Daly, Lawrence W. Bergman,
James M. Burns, Jr.
(ACMCIP Abstract)
797
803
IDENTIFICATION OF THE ETIOLOGIC AGENT OF THE EPIDEMIC
OF CUTANEOUS LEISHMANIASIS IN TOLIMA, COLOMBIA
TRANSPLACENTAL TRANSFER OF MSP142 USING THE IN VITRO
PLACENTAL PERFUSION MODEL
Isabel Rodriguez-Barraquer1, Rafael Góngora1, Robinson Pacheco1,
Adriana Navas1, Cristina Ferro2, Marta Ayala2, Martín Prager1,
Maria Consuelo Miranda1, Nancy Gore Saravia1
Karen May1, Indu Malhotra2, Marcus Grube1, Carole Long3, Kishor
Mandaliya4, Christoph Fusch1, Henning Schneider5,
Christopher L. King2
1
1
Ernst Moritz Arndt University of Greifswald, Greifswald, Germany, 2Case
Western Reserve University, Cleveland, OH, United States, 3National
Institutes of Health, Bethesda, MD, United States, 4Pathology Services
Kenyan Ministry of Health, Mombasa, Kenya, 5University of Berne, Berne,
Switzerland
CIDEIM, Cali, Colombia, 2Instituto Nacional de Salud, Bogotá, Colombia
798
ANALYSIS OF PLASMODIUM FALCIPARUM MAL13P1.319, A
SPOROZOITE GENE
Renee N. Roberts, Michael Kariuki, Alexis LaCrue, Ruguang Ou,
Brenda Beerntsen
(ACMCIP Abstract)
799
ACUTE LUNG INJURY IN A SEVERE MALARIA MODEL IS
DEPENDENT ON TOTAL PARASITE BURDEN AND CD36DEPENDENT LOCAL SEQUESTRATION IN THE LUNG
Fiona E. Lovegrove, Samir N. Patel, Andrea Conroy, W. Conrad
Liles, Kevin C. Kain
Toronto, ON, Canada
(ACMCIP Abstract)
804
PLASMODIUM DERIVED FACTORS INDUCE APOPTOSIS IN
HUMAN NEUROGLIA AND VASCULAR ENDOTHELIAL CELLS
Nana Wilson, Mingbo Huang, Vincent Bond, Michael Powell,
Kiantra I. Ramey, Henry Armah, September Hesse, Kwaku Asare,
Jonathan K. Stiles
(ACMCIP Abstract)
805
PLASMODIUM BERGHEI ANKA IS ASSOCIATED WITH COGNITIVE DYSFUNCTION IN MICE
Mahalia S. Desruisseaux1, Maria Gulinello1, Sunhee Lee1, David
Smith1, Moriya Tsuji2, David C. Spray1, Herbert B. Tanowitz1
1
Albert Einstein College of Medicine, Bronx, NY, United States, 2ADARC
Rockefeller University, New York, NY, United States
172
806
www.astmh.org
811
FUNCTIONAL ASSESSMENT OF A 72KDA PUTATIVE GLUCOSE
REGULATED PROTEIN IN PLASMODIUM KNOWLESI BLOODSTAGE PARASITES
AVOIDING MISCLASSIFICATION OF RECURRENT PLASMODIUM
FALCIPARUM PARASITEMIAS AFTER THERAPY
Sheila Akinyi , Cindy C. Korir , Balwan Singh , John W. Barnwell ,
Mary R. Galinski1
Jonathan J. Juliano1, Emily Wenink1, Frederic Ariey2, Pharath Lim2,
Noppadon Tangpukdee3, Srivicha Krudsood3, Carol Olson4, Sornchai
Looareesuwan3, Steven R. Meshnick1
1
1
1
1
1
2
Emory University - Emory Vaccine Center, Atlanta, GA, United States,
Centers for Disease Control and Prevention - Division of Parasitic Diseases National Center for Infectious Diseases, Atlanta, GA, United States
2
University of North Carolina, Chapel Hill, NC, United States, 2Institut Pasteur
du Cambodge, Phnom Penh, Cambodia, 3Hospital for Tropical Diseases,
Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand,
4
Immtech Pharmaceuticals, Inc., Vernon Hills, IL, United States
(ACMCIP Abstract)
812
807
THE MURINE COMA AND BEHAVIOR SCORE: A RAPID
ASSESSMENT TOOL FOR MURINE CEREBRAL MALARIA
Ryan W. Carroll
808
ESTIMATION OF MALARIA PARASITE DENSITY IN URINE AND
SALIVA SAMPLES USING REAL-TIME QUANTITATIVE PCR
(QPCR) METHODS
Davis Nwakanma1, Natalia Gomez-Escobar1, Michael Walther1,
Sarah Crozier1, Elissa Malkin2, Emily Locke2, David Conway1
1
UK, Medical Research Council Laboratories, The Gambia, Banjul, Gambia,
The PATH Malaria Vaccine Initiative, Bethesda, MD, United States
2
Stephen Rogerson1, Elizabeth Aitken1, Gaoqian Feng1, Bernard
Mbewe2, Linda Kalilani2, Per Ashorn3, Steven Meshnick4
1
University of Melbourne, Parkville Victoria, Australia, 2College of Medicine,
University of Malawi, Blantyre, Malawi, 3University of Tapere, Tampere,
Finland, 4University of North Carolina, Chapel Hill, NC, United States
(ACMCIP Abstract)
Malaria - Diagnosis
809
813
SEVERE THROMBOCYTOPENIA: A CLUE IN A PATIENT
WITH MALARIA
Ihosvani Miguel, Naile Barzaga, Deborah Asnis
814
COMPARISON OF BLOOD SMEAR MICROSCOPY AND PCR
BASED METHODS IN THE DETECTION OF PLASMODIUM FALCIPARUM IN ACTIVE SURVEILLANCE FOR HIGHLAND MALARIA
IN WESTERN KENYA
ENHANCED DETECTION OF GAMETOCYTES PREDICTS HIGHER
POTENTIAL FOR PLASMODIUM FALCIPARUM TRANSMISSION
David M. Menge1, Kacey C. Ernst2, John Vulule3, Peter A.
Stephan Karl1, Brian T. Grimberg2, Lee R. Moore3, Makindi David4,
Pascal Michon4, Ivo Mueller5, Maciej Zborowski3, Peter A.
Zimmerman2
1
1
University of Technology Dresden, Dresden, Germany, 2The Center of
Global Health and Disease, Case Western Reserve University, Cleveland, OH,
United States, 3Cleveland Clinics, Lerner Research Institute, Department of
Biomedical Engineering, Cleveland, OH, United States, 4Molecular
Parasitology Unit, Institute of Medical Resarch Papua New Guinea, Madang,
Papua New Guinea, 5Vector Borne Diseases, Goroka, Papua New Guinea
810
EVALUATION OF REAL-TIME PCR PROTOCOLS FOR LABORATORY DIAGNOSIS OF MALARIA
Ozgur Koru, Yvonne Qvarnstrom, Susan B. Slemenda, Maniphet
Xayavong, Stephanie P. Johnston, Alexandre J. da Silva
Center for Infectious Diseases and Microbiology Translational Research,
University of Minnesota, Minneapolis, MN, United States, 2University of
Michigan School of Public Health, Ann Arbor, MI, United States, 3Center for
Vector Biology and Control Research, Kenya Medical Research Institute,
Kisumu, Kenya, 4The Center for Global Health and Diseases, Case Western
Reserve University School of Medicine, Cleveland, OH, United States
815
SPECIATION OF ALL FOUR HUMAN MALARIA PARASITES IN A
SINGLE, MULTIPLEX REAL-TIME PCR REACTION
Sandra E. Shokoples1, Momar Ndao2, Kinga KowalewskaGrochowska3, Stephanie K. Yanow1
1
Provincial Laboratory for Public Health, Edmonton, AB, Canada, 2McGill
University, Montreal, QC, Canada, 3University of Alberta, Edmonton,
AB, Canada
173
VARIANT SPECIFIC IMMUNITY TO MALARIA IN PREGNANCY:
PROTECTION AGAINST ANAEMIA AND REINFECTION, AND
EFFECTS OF IPTP ON DEVELOPMENT OF ANTIBODY
Detailed Program
www.astmh.org
822
816
NEW INSIGHT ON ORALLY-ACTIVE ACRIDONE
ANTIMALARIALS: STRUCTURAL AND FUNCTIONAL DIVERSITY
DB75, A NOVEL DIAMIDINE, DEMONSTRATES A
STAGE SPECIFIC KILLING ACTION AND UPREGULATES
DNA PRIMASE EXPRESSION
Anne E. Purfield, Richard R. Tidwell, Steven R. Meshnick
Jane X. Kelly1, Martin Smilkstein1, Rolf Winter1, Rosie Dodean1,
Arba Ager2, Dave Hinrichs1, Mike Riscoe1
1
Portland VA Medical Center, Portland, OR, United States, 2University of
Miami, Miami, FL, United States
University of North Carolina at Chapel Hill, Chapel Hill, NC, United States
823
817
USING 3D-QSAR TO IDENTIFY NEW CHEMICAL CLASSES THAT
SPECIFICALLY INHIBIT BETA-KETOACYL ACP SYNTHASE III
(PFKASIII) IN PLASMODIUM FALCIPARUM
Heather W. Gaona1, Patricia J. Lee1, Jayendra B. Bhonsle1, Sean T.
Prigge2, Thomas H. Hudson1, Kevin A. Reynolds3, William F.
McCalmont1, Tiffany N. Heady1, Donald P. Huddler1, Mara
Kreishman-Deitrick1, Apurba K. Bhattacharjee1, Lucia Gerena1,
Norma E. Roncal1, Miriam Lopez-Sanchez1, Jacob D. Johnson1,
Norman C. Waters1
1
2
Johns Hopkins University, School of Public Health, Baltimore, MD, United
States, 3Portland State University, Portland, OR, United States
818
CONTRIBUTION OF POLYMORPHISM IN PFCRT, PFMDR1 AND
PFNHE GENES IN THE REVERSAL OF QUINOLINE RESISTANCE
IN PLASMODIUM FALCIPARUM
Maud Henry1, Sandrine Alibert2, Eric Baret1, Joel Mosnier1, Thierry
Fusai1, Jacques Barbe2, Christophe Rogier1, Bruno Pradines1
1
Institut de Médecine Tropicale du Service de Santé des Armées, Marseille,
France, 2GERCTOP-UMR CNRS 6178 Faculté de Pharmacie, Marseille, France
819
THE RELATIONSHIP BETWEEN SUBSTITUTED 1,7DIAMINOISOQUINOLINE STRUCTURE AND
ANTIMALARIAL ACTIVITY
Clare E. Gutteridge1, Apurba K. Bhattacharjee2, Marshall M.
Hoffman1
1
United States Naval Academy, Annapolis, MD, United States, 2Walter Reed
Army Institute of Research, Silver Spring, MD, United States
820
ASSESSMENT OF MALARIA IN VITRO DRUG COMBINATION
SCREENING AND MIXED STRAIN INFECTIONS USING THE SYBR
GREEN FLUORESCENCE ASSAY
Drew D. Reinbold, Richard A. Dennull, Norman C. Waters, Jacob
D. Johnson
821
A COLORIMETRIC HIGH THROUGHPUT SCREEN FOR THE
DETECTION OF HEME CRYSTALLIZATION INHIBITORS
Margaret A. Rush1, Ralph Mazitschek2, Mary L. Baniecki1, Roger
Weigand2, Jon Clardy3, Dyann F. Wirth1
IDENTIFYING NOVEL DRUG TARGETS FOR PLASMODIUM FALCIPARUM THYMIDYLATE SYNTHASE DIHYDROFOLATE
REDUCTASE
Tina Dasgupta, Karen S. Anderson
(ACMCIP Abstract)
824
DISCOVERY OF POTENT, SPECIES-SELECTIVE INHIBITORS OF
PLASMODIUM FALCIPARUM DIHYDROOROTATE DEHYDROGENASE THAT POSSESS ANTIMALARIAL ACTIVITY
Vishal Patel1, Michael L. Booker2, Jon Clardy1, Dyann F. Wirth3
1
Harvard Medical School, Boston, MA, United States, 2Genzyme
Corporation, Waltham, MA, United States, 3Harvard School of Public Health,
Boston, MA, United States
(ACMCIP Abstract)
825
NEW GENOME-BASED DRUG TARGET IDENTIFICATION
PLATFORM FOR PLASMODIUM
Jian Sun, Xuebin Zhang, Lee A. Bulla
Biological Targets, Inc., Pilot Point, TX, United States
(ACMCIP Abstract)
826
ANTIMALARIAL PYRIDONES: IN VITRO
PHARMACODYNAMIC STUDIES
Esperanza Herreros, Jaume Vidal, Maria J. Almela, Maria
Roncales, Pedro Torres, Sonia Lozano, Marina del Rosal, Domingo
Gargallo
(ACMCIP Abstract)
Malaria – Drug Resistance
827
HAPLOTYPE PROFILING OF SP-RESISTANT STRAINS OF
PLASMODIUM FALCIPARUM FROM KILIFI, KENYA, 1987-2006
Laura K. Certain1, Marnie R. Briceno1, Alexis M. Nzila2, Carol
Hopkins Sibley1
1
University of Washington, Seattle, WA, United States, 2Kemri/Wellcome
Trust Research Program, Centre for Geographic Medicine Research - Coast,
Kilifi, Kenya
(ACMCIP Abstract)
1
Institute of Harvard University and MIT, Cambridge, MA, United States,
3
174
828
833
LONGITUDINAL SURVEY OF ANTIMALARIAL RESISTANCE IN
KILIFI, KENYA, 1987-2006
Marnie R. Briceno1, Laura K. Certain1, Alexis M. Nzila2, Carol
Hopkins Sibley1
1
www.astmh.org
2
University of Washington, Seattle, WA, United States, Kemri/Wellcome
Trust Research Program, Centre for Geographic Medicine Research - Coast,
Kilifi, Kenya
(ACMCIP Abstract)
CHLOROQUINE - RESISTANCE MOLECULAR MARKERS (PFCRT
T76 AND PFMDR-1 Y86) AND AMODIAQUINE RESISTANCE IN
BURKINA FASO
Halidou Tiinto1, Guekoun Lougué2, Issaka Zongo3, Robert Tinga
Guiguemdé2, Umberto D’Alessandro4, Jean Bosco Ouédraogo1
1
IRSS/Centre Muraz, Bobo Dioulasso, Burkina Faso, 2Centre Muraz, Bobo
Dioulasso, Burkina Faso, 3IRSS, Bobo Dioulasso, Burkina Faso, 4Institute of
Tropical Medicine, Antwerp, Belgium
829
834
THE IMPACT OF INCOMPLETE WITHDRAWL OF CHLOROQUINE
USE ON THE RATE OF DECLINE IN CHLOROQUINE RESISTANT
PLASMODIUM FALCIPARUM PARASITES UNDER DIFFERENT
TRANSMISSION CONDITIONS
STABLE RELATIONSHIP BETWEEN MOLECULAR MARKERS FOR
SULFADOXINE-PYRIMETHAMINE RESISTANCE AND CLINICAL
OUTCOMES AS EFFICACY DECLINES
Michelle L. Gatton1, Qin Cheng2
1
Queensland Institute of Medical Research, Herston, Australia, 2Australian
Army Malaria Institute, Brisbane, Australia
Matthew B. Laurens1, Amber D. Gaither2, Fraction K.
Dzinjalamala3, Phillip C. Thesing1, Terrie E. Taylor4, Christopher V.
Plowe1, Miriam K. Laufer1
1
University of Maryland Baltimore County, Catonsville, MD, United States,
3
University of Malawi College of Medicine, Blantyre, Malawi, 4Michigan
State University, East Lansing, MI, United States
2
EFFICACY OF INTERMITTENT TREATMENT WITH SULFADOXINE-PYRIMETHAMINE ALONE OR SULFADOXINEPYRIMETHAMINE PLUS ARTESUNATE FOR PREVENTION OF
PLACENTAL MALARIA IN TANZANIA
John R. MacArthur1, Abdunoor M. Kabanywanyi2, Abdullah Baja2,
Vera Juma2, Charles Maswi2, Peter B. Bloland1, S. Patrick Kachur1,
Salim Abdulla2
1
2
831
PFNHE POLYMORPHISM IN WILD ISOLATES OF P. FALCIPARUM
FROM DIFFERENT CONTINENTS WITH A LOW SENSITIVITY TO
QUININE
Stephane Pelleau1, Jacques Le bras2, Frederic Ariey3, Sandra
Corre1, Yacine Seck1, Phawath Lim3, Ndeye Bob Sakha1, Ronan
Jambou1
835
IN VITRO ANTIMALARIAL DRUG RESPONSE OF FRESH P. FALCIPARUM ISOLATES FROM MALI
Souleymane Dama1, Bakary Fofana1, Bakary Sidibe1, Demba
Dembele1, Sekou Toure1, Jean Bosco Ouedraogo2, Ogobara K.
Doumbo1, Abdoulaye A. Djimde1
1
University of Bamako, Bamako, Mali, 2Institut de Recherche en Sciences de
la Santé, Bobo-Dioulasso, Burkina Faso
836
AN ABCG HOMOLOGUE GENE IN MULTI-DRUG RESISTANT
PLASMODIUM YOELII
Ivan Ferrer-Rodriguez1, Bárbara González1, Glenda Rodríguez1,
Edalish Gascot1, Gloriene González1, Adelfa E. Serrano2
1
Inter American University of Puerto Rico, Bayamón, PR, United States,
Department of Microbiology and Medical Zoology, University of Puerto
Rico, School of Medicine, San Juan, PR, United States
2
1
Institut Pasteur de Dakar, Dakar, Senegal, 2Hopital Bichat Claude Bernard,
Paris, France, 3Institut Pasteur du Cambodge, Phnom Penh, Cambodia
(ACMCIP Abstract)
832
EXAMINATION OF MOLECULAR MARKERS OF RESISTANCE
IN ARTEMISININ COMBINATION THERAPY (ACT) FAILURES
FOUND ALONG THE THAI/CAMBODIAN BORDER
Kurt E. Schaecher, Harald Noedl, Anintita Laoboonchai,
Mark Fukuda
837
COLOMBIAN NETWORK FOR SURVEILLANCE OF P. FALCIPARUM IN VITRO SUSCEPTIBILITY TO ANTIMALARIAL DRUGS
Diego Echeverry1, Samanda Aponte1, Claudia Quelal2, Dario
Ibarguen3, Mariela Huertas3, Melisa Rios4, Luz Mila Murcia4, Ligia
del Pilar Pérez4, Pilar Pérez2, Zulma Bejarano3, Pedro Gil5, Anders
Björkman5, Lyda Osorio1
1
International Center for Medical Research and Training (CIDEIM), Cali,
Colombia, 2Control de Vectores-Instituto Departamental de Salud de Nariño,
Tumaco, Colombia, 3Laboratorio Departamental-DASALUD Chocó, Quibdo,
Colombia, 4Secretaría de Salud del Amazonas, Leticia, Colombia, 5Malaria
Research laboratory-Karolinska Institute, Stockholm, Sweden
175
830
Detailed Program
www.astmh.org
838
843
DISTINCTION OF RECRUDESCENCE AND RE-INFECTION BY
MSP2 GENOTYPING: AN EMPIRICAL STANDARDIZATION OF
CLASSIFICATION CRITERIA
USE OF PREVENTIVE MEASURES FOR MALARIA AMONG
WOMEN DELIVERING IN A RURAL DISTRICT HOSPITAL IN
NORTH-EASTERN TANZANIA
Petrica Rouse1, Mtawa Mkulama2, Philip E. Thuma2, Sungano
Mharakurwa2
John P. Lusingu1, Baliyima Lelo1, Bruno P. Mmbando1,
Lasse S. Vestergaard2, Andrew Y. Kitua3, Martha M. Lemnge1,
Thor G. Theander4
1
States, 2The Malaria Institute at Macha, Choma, Zambia
1
National Institute for Medical Research, Tanga, United Republic of Tanzania,
Serum Statens Institute, Copenhagen, Denmark, 3National Institute for
Medical Research, Dar es Salaam, United Republic of Tanzania, 4CMP,
University of Copenhagen, Copenhagen, Denmark
2
839
ASSESSMENT OF EXPRESSION OF THE PLASMODIUM
FALCIPARUM CHLOROQUINE RESISTANCE TRANSPORTER
GENE (PFCRT) IN THE ASEXUAL SATGES OF MALARIA
PARASITES USING REAL-TIME PCR
Tunika I. Okatcha, Donald J. Krogstad
840
844
OPTIMIZING MALARIA CONTROL SUPPLY SYSTEM
PLANNING AND MANAGEMENT FOR SCALING UP
NATION-WIDE ITN DISTRIBUTION
Paul C. Libiszowski1, Cecelia Katebe2, Kafula Silumbe3,
John Miller4, Abdirahman Mohamed4, Fay Venegas4,
Richard W. Steketee1
1
PATH, Ferney-Voltaire, France, 2Zambia Ministry of Health, Lusaka, Zambia,
PATH-MACEPA, Lusaka, Zambia, 4PATH, Seattle, WA, United States
3
GENETIC DIVERSITY OF MEROZOITE SURFACE PROTEIN-1
GENE OF THE KOREAN ISOLATES OF PLASMODIUM VIVAX
Eun Taek Han1, Jun Hu Chen1, Jong Yil Chai2
1
Department of Parasitology Kangwon National University College of
Medicine, Chuncheon-si, Gangwon-do Republic of Korea, 2Department of
Parasitology and Tropical Medicine, Seoul National University College of
Medicine, Seoul, Republic of Korea
841
ZAMBIAN INDOOR RESIDUAL SPRAYING (IRS) PROGRAM: A
GEOGRAPHIC INFORMATION SYSTEM (GIS) TO SUPPORT IRS
PLANNING AND MANAGEMENT
Christopher Lungu1, Chadwick Sikaala1, Brian Chirwa1,
Mercy Mwanza1, Chilandu Mukuka1, John M. Miller2
845
THE COUNTER-INTUITIVE INFLUENCE OF SOCIAL ECONOMIC
STATUS AND EDUCATION LEVEL UPON MALARIA PREVALENCE: ARE RICHER PEOPLE AT GREATER RISK OF INFECTION?
Yvonne Geissbühler1, Khadija Kannady2, Prosper Chaki3, Nicodem
Govella3, Deo Mtasiwa4, Steven Lindsay5, Ulrike Fillinger5, Marcel
Tanner1, Marcia Castro6, Gerry Killeen3
1
Swiss Tropical Institute, Basel, Switzerland, 2Dar es Salaam Urban Malaria
Control Programme, Dar es Salaam, United Republic of Tanzania, 3Ifakara
Health Research and Development Centre, Dar es Salaam, United Republic
of Tanzania, 4Dar es Salaam City Council, Dar es Salaam, United Republic of
Tanzania, 5Durham University, Durham, United Kingdom, 6Harvard
846
1
Zambia Ministry of Health, Lusaka, Zambia, 2PATH, Seattle, WA,
United States
842
ESTABLISHMENT AND STRENGTHENING OF SITES FOR
MALARIA VACCINE TRIALS IN KOROGWE DISTRICT, TANGA
REGION, NORTH-EAST TANZANIA: DSS, MALARIA SURVEILLANCE, MALARIA EPIDEMIOLOGY AND HUMAN IMMUNE
RESPONSES TO MSP3
Bruno P. Mmbando, Method D. Segeja, Deus Ishengoma, John P.
Lusingu, Hamisi A. Msangeni, Samwel H. Sembuche, Misago Seth,
Filbert Francis, Ezekiel K. Malecela, Juma A. Akida, Rashidi Madebe,
Masunga M. Chille, Johari Sadi, Acleus S. Rutta, Mathias L.
Kamugisha, Martha M. Lemnge
THE AGE-RELATED PATTERN OF INFECTIOUSNESS WITH P. FALCIPARUM ASSESSED BY MEMBRANE FEEDING ASSAYS: ASSOCIATION WITH SEXUAL STAGE-SPECIFIC ANTIBODIES OF POPULATIONS LIVING UNDER NATURAL MALARIA TRANSMISSION
PRESSURE IN BURKINA FASO
André Lin Ouedraogo1, Awa Gnémé1, Edith Ilboudo-Sanogo1,
Roeffen Will2, Petra Schneider2, Jan Peter Verhave2, Issa Nébié1,
Nadine Cuzin-Ouattara1, Robert Sauerwein2
1
Centre National de Recherche et de Formation sur le paludisme (CNRFP),
Ouagadougou, Burkina Faso, 2Medical Microbiology, Radboud University
Medical Centre, Nijmegen, The Netherlands
(ACMCIP Abstract)
847
National Institute for Medical Research, Tanga, United Republic of Tanzania
USING DENATURING HPLC TO GENOTYPE P. FALCIPARUM
GENES - APPLICATION TO THE VACCINE CANDIDATE PFMSP3
Stephen J. Jordan, Michael R. Crowley, OraLee H. Branch,
Julian C. Rayner
176
848
853
THE DAR ES SALAAM URBAN MALARIA CONTROL
PROGRAMME: EARLY LESSONS AFTER ONE YEAR OF SYSTEMATIC LARVICIDING
Khadija Kannady1, Ulrike Fillinger2, Yvonne Geissbühler3,
Prosper Chaki4, Stefan Dongus3, Nicodem Govella4, Deo Mtasiwa5,
Hassan Mshinda4, Marcel Tanner3, Steven Lindsay2, Marcia Castro6,
Gerry Killeen4
1
Dar es Salaam Urban Malaria Control Programme, Dar es Salaam, United
Republic of Tanzania, 2Durham University, Durham, United Kingdom, 3Swiss
Tropical Institute, Basel, Switzerland, 4Ifakara Health Research and
Development Centre, Dar es Salaam, United Republic of Tanzania, 5Dar es
Salaam City Council, Dar es Salaam, United Republic of Tanzania, 6Harvard
849
CAN RIVER BLINDNESS VILLAGE WORKERS IMPROVE THE
QUALITY OF LLIN DISTRIBUTION? A MOSQUITO NET COVERAGE AND MALARIA PREVALENCE IN OROMIYA AND SNNP
REGIONS OF ETHIOPIA, 2006-2007
Patricia Graves1, Yeshewamebrat Ejigsemahu2, Estifanos Biru2,
Aryc Mosher1, Jeremiah Ngondi1, Teshome Gebre2, Tekola
Endeshaw2, Paul Emerson1, Afework Hailemarian3, Frank O.
Richards1
David M. Menge1, Kacey C. Ernst2, John Vulule3, Chandy C. John1
1
Center for Infectious Diseases and Microbiology Translational Research,
University of Minnesota, Minneapolis, MN, United States, 2University of
Michigan School of Public Health, Ann Arbor, MI, United States, 3Center for
Vector Biology and Control Research, Kenya Medical Research Institute,
Kisumu, Kenya
854
IMPLICATIONS OF GENOME WIDE ALLELIC DIVERSITY
SCANS FOR HIGH RESOLUTION GENETIC MAPPING IN
Sajeewani U. Samarakoon, Jigar J. Patel, Michael T. Ferdig
University of Notre Dame, South Bend, IN, United States
CHARACTERISATION OF THE MITOCHONDRIAL ATP SYNTHASE/HYDROLASE COMPLEX OF THE MODEL PROTIST
TETRAHYMENA THERMOPHILA
Carter Center, Atlanta, GA, United States, 2Carter Center, Addis Ababa,
Ethiopia, 3Federal Ministry of Health, Addis Ababa, Ethiopia
Praveen Balabaskaran Nina, Michael W. Mather, Akhil B. Vaidya
850
Patrick L. Sutton1, Simon Kang’a2, Jean N. Hernandez3, Emilio F.
Merino2, Carlos E. Vidal4, Jane Carlton2, OraLee H. Branch1
1
University of Alabama at Birmingham, Department. of Medicine,
Birmingham, AL, United States, 2University of New York, Department. of
Medical Parasitology, New York, NY, United States, 3University Nacional de la
Amazonia Peruana, Iquitos, Peru, 4Ministerio de Salud, Direccion de SaludLoreto, Iquitos, Peru
(ACMCIP Abstract)
856
PROSPECTIVE STUDIES OF CHILDREN WITH ASYMPTOMATIC
P. FALCIPARUM INFECTION IN MISSIRA, MALI: GENETIC
HETEROGENEITY REVEALED BY SEQUENCING
B. M. Mack1, Ousmane Aliou Koita2, Mamadou Weleba
Bagayoko2, Aliou Coulibaly2, A. Sissako2, J. M. Colborn1,
Donald J. Krogstad1
1
Tulane University, New Orleans, LA, United States, 2University of Bamako
Faculty of Science, Bamako, Mali
851
SPATIAL ASPECTS OF MALARIA CONTROL WITH LARVICIDES
AND ENVIRONMENTAL MANAGEMENT IN DAR ES SALAAM,
TANZANIA
2
3
Marcia C. Castro , Khadija Kannady , Burton H. Singer , Deo
Mtasiwa2, Hassan Mshinda4, Marcel Tanner5, Steve W. Lindsay6,
Ulrike Fillinger6, Gerry F. Killeen4
MITOCHONDRIAL ATPASE ACTIVITY IN INTRAERYTHROCYTIC
MALARIA PARASITES
Michael W. Mather, Joanne M. Morrisey, Praveen Balabaskaran
Nina, Akhil B. Vaidya
1
Harvard School of Public Health, Boston, MA, United States, 2Dar es
Salaam City Council, Dar es Salaam, United Republic of Tanzania, 3Princeton
University, Princeton, NJ, United States, 4Ifakara Health Research and
Development Centre, Dar es Salaam, United Republic of Tanzania, 5Swiss
Tropical Institute, Basel, Switzerland, 6Durham University, Durham, United
Kingdom
852
(ACMCIP Abstract)
858
ASSESSING THE ROLE OF MITOCHONDRIAL ELECTRON
TRANSPORT IN IN VIVO SURVIVAL OF PLASMODIUM BERGHEI
Suresh M. Ganesan, Joanne M. Morrisey, Heather J. Painter, Mike
W. Mather, Akhil B. Vaidya
CIRCUMSPOROZOITE AND MSP1 POLYMORPHISM AMONG
PLASMODIUM VIVAX ISOLATES FROM SOUTHERN MEXICO
1
857
1
Lilia Gonzalez-Ceron , Jose A. Nettel-Cruz , Ciro Montero-Solis ,
Frida Santillan1, Marco A. Sandoval1, Rosa Gomez2
(ACMCIP Abstract)
1
National Institute for Public Health, Tapachula, Chiapas, Mexico, 2National
Institute for Public health, Cuernavaca, Mor, Mexico
177
WITHIN-HOST AND POPULATION-LEVEL GENETIC DIVERSITY
OF PLASMODIUM VIVAX IN PERU
1
GENETIC DIVERSITY OF PLASMODIUM FALCIPARUM IN SITES
WITH VARYING TRANSMISSION PATTERNS IN A WESTERN
KENYA HIGHLAND
855
1
1
www.astmh.org
Detailed Program
www.astmh.org
859
866
CAN THE MITOCHONDRIAL GENOME IN ERYTHROCYTIC
PLASMODIUM FALCIPARUM BE DEPLETED?
MOLECULAR DIFFERENTIATION OF ANOPHELINE SPECIES
FROM NORTHEAST PERU
Hangjun Ke, Heather J. Painter, Praveen Balabaskaran, Suresh
Ganesan, Joanne M. Morrisey, Michael W. Mather, Akhil B. Vaidya
Ryan Matson1, Carlos Tong2, Margaret Kosek3, Robert Gilman3,
David Florin4, Joseph Vinetz1
1
University of California, San Diego, La Jolla, CA, United States, 2Navy
Medical Research Center Detachment, Iquitos, Peru, 3Johns Hopkins School
of Public Health, Baltimore, MD, United States, 4Navy Medical Research
Center Detatchment, Lima, Peru
(ACMCIP Abstract)
860
COMPARATIVE STUDY OF THE GENETIC DIVERSITY
OF THE RHOPTRY-ASSOCIATED PROTEIN 1 (RAP-1) IN
PLASMODIUM SPP.
Maria A. Pacheco, Elizabeth M. Ryan, Ananias A. Escalante
Arizona State University, Tempe, AZ, United States
(ACMCIP Abstract)
861
CHARACTERIZATION OF PLASMODIUM FALCIPARUM SPOROZOITE GENE PFA0490W
867
GENETIC RELATIONSHIPS AMONG AEDES AEGYPTI COLLECTIONS IN VENEZUELA AS DETERMINED BY SINGLE
NUCLEOTIDE AND DELETION-INSERTION POLYMORPHISMS
Ludmel Urdaneta-Marquez1, William C Black1, Flor Herrera2,
Yasmin Rubio-Palis2, Christopher Bosio1
1
Department of Microbiology, Immunology and Pathology, Colorado State
University, Fort Collins, CO, United States, 2Centro de Investigaciones
Biomedicas (BIOMED), Universidad de Carabobo-Nucleo Aragua, Maracay,
Venezuela
Michael M. Kariuki, Ruguang Ou, Alexis N. LaCrue, Reneè N.
Roberts, Maggie S. Schlarman, Brenda T. Beerntsen
(ACMCIP Abstract)
862
STRUCTURE AND FUNCTION OF PLASMODIUM FALCIPARUM
MALATE DEHYDROGENASE: ANALYSIS OF N-TERMINAL DINUCLEOTIDE BINDING FOLD BY SITE-DIRECTED MUTAGENESIS
Anupam Pradhan, Prashant V. Desai, Mitchell A. Avery, Larry A.
Walker, Babu L. Tekwani
School of Pharmacy, University of Mississippi, University, MS, United States
(ACMCIP Abstract)
863
868
DENSITY AND SPECIES COMPOSITION OF ANOPHELES GAMBIAE S.L IN BANAMBANI, MALI
Mahamoudou B. Toure1, Nickolas Manoukis2, Boubacar Guindo3,
Ibrahim M. Sissoko3, Sekou F. Traore3, Seydou Doumbia3,
Charles E. Taylor1
1
UCLA, Los Angeles, CA, United States, 2National Institutes of Health,
Washington DC, United States, 3MRTC - FMPOS, Bamako, Mali
869
A PHYSICAL MAP FOR THE ASIAN MALARIA VECTOR
ANOPHELES STEPHENSI
Ai Xia1, Maria V. Sharakhova1, Zhijian Tu1, Yogesh S. Shouche2,
Igor V. Sharakhov1
1
POLYMORPHISMS OF PLASMODIUM VIVAX DUFFY BINDING
PROTEIN IN ISOLATES FROM THAI PATIENTS
Panita Gosi1, Mark Fukuda1, Kurt Schaecher1, David Lanar2, Srisin
Khusmith3, Thareerat Khalambaheti3, Scott Miller2
1
the Medical Sciences, Bangkok, Thailand, 2Walter Reed Army Institute of
Research, Silver Spring, MD, United States, 3Mahidol University, Bangkok,
Thailand
Virginia Tech, Blacksburg, VA, United States, 2National Centre for Cell
Science, Pune, India
870
GENETIC LINKAGE MAPPING IN THE WEST NILE VIRUS VECTOR CULEX TARSALIS
Meera Venkatesan1, Morgan Sellers2, Jason L. Rasgon1
1
States, 2Johns Hopkins University, Baltimore, MD, United States
Mosquitoes – Molecular Genetics
864
FIRST REPORT ON POPULATION STRUCTURE FOR THE
LEISHMANIA MAJOR VECTOR, PHLEBOTOMUS PAPATASI
SANDFLY USING MICROSATELLITE LOCI
Omar Y. Hamarsheh, Wolfgang Presber, Gabriele Schönian
Charite Universitätsmedizin Berlin, berlin, Germany
871
PRELIMINARY DATA ON INSERTION POLYMORPHISMS OF
SINE200 ALONG THE 2L CHROMOSOMAL ARM IN ANOPHELES
GAMBIAE
Emiliano Mancini1, Federica Santolamazza1, Yumin Qi2, Zhijian
Tu2, Alessandra della Torre1
1
Dipartimento di Scienze di Sanità Pubblica, Università di Roma “La
Sapienza”, Rome, Italy, 2Department of Biochemistry, Virginia Polytechnic
Institute and State University, Blacksburg, VA, United States
178
872
www.astmh.org
877
PATTERNS OF SELECTION ON ANTI-MALARIAL IMMUNE
GENES: ADAPTIVE EVOLUTION IN LRIM1 IN ANOPHELES ARABIENSIS
MOLECULAR IDENTIFICATION OF THE MEMBERS OF THE
ANOPHELES ANNULARIS GROUP OF MOSQUITOES (DIPTERA:
CULICIDAE) USING RIBOSOMAL DNA ITS2 AND DOMAIN-3
Michel A. Slotman1, Aristeidis Parmakelis1, Jonathon C. Marshall1,
Nikolaos Poulakakis1, Parfait H. Awono-Ambene2,
Christophe Antonio-Nkondjio2, Frederic Simard2,
Adalgisa Caccone1, Jeffrey R. Powell1
Mohammad T. Alam1, Manoj K. Das2, Vas Dev3, Yagya D. Sharma1
1
All India Institute of Medical Sciences, New Delhi, India, 2National Institute
of Malaria Research (Field Station), Ranchi, India, 3National Institute of
Malaria Research (Field Station), Sonapur, India
1
873
DIFFERENTIAL GENE EXPRESSION AMONG SUSCEPTIBLE AND
REFRACTORY STRAINS OF AEDES AEGYPTI MOSQUITOES FOLLOWING DENGUE 2 INFECTED BLOOD MEALS
Irene N. Kasumba, David Severson
878
DEMOGRAPHIC HISTORY CAN INFLUENCE PRESENT ESTIMATES OF GENE FLOW: A CASE STUDY OF THE WEST NILE
VIRUS VECTOR CULEX TARSALIS
Jason L. Rasgon, Meera Venkatesan, M. Claire Hauer
United States
Center for Global Health and Infectious Diseases, Department of Biological
Sciences, University of Notre Dame, Notre Dame, IN, United States
879
874
COMPARATIVE TIME COURSE GENE-EXPRESSION PROFILING IN
DENGUE SUSCEPTIBLE (MOYO-S) AND REFRACTORY (MOYOIN DRY) STRAINS OF AEDES AEGYPTI IN RESPONSE TO
DENGUE INFECTION
Chitra Chauhan, Brent Harker, Becky deBruyn, Consuelo GomezMachorro, Diane Lovin, Jeanne Romero-Severson, David W.
Severson
FREQUENCY OF MULTIPLE HUMAN BLOODMEALS
TAKEN BY FEMALE ANOPHELES ARABIENSIS MOSQUITOES
IN MACHA, ZAMBIA
Laura C. Norris1, Christen M. Fornadel1, Rebekah J. Kent2, Douglas
E. Norris1
1
States, 2Centers for Disease Control and Prevention, Fort Collins, CO, United
States
The Center for Global Health and Infectious Diseases, University of Notre
Dame, Notre Dame, IN, United States
875
IMPLICATIONS OF HYBRIDIZATION, FEEDING BEHAVIOR AND
PARITY RATES OF CULEX PIPIENS ON WEST NILE VIRUS ACTIVITY AT STABLE ENZOOTIC STUDY SITES
Linda-Lou O’Connor1, John B. Gingrich1, Dina Fonseca2, Thomas
R. Unnasch3
1
University of Delaware, Newark, DE, United States, 2Rutgers University,
New Brunswick, NJ, United States, 3University of Alabama at Birmingham,
Birmingham, AL, United States
880
PASSERINE FILARIASIS AND THE RAPID SPREAD OF WEST NILE
VIRUS - A REAL-LIFE EXAMPLE OF MICROFILARIAL ENHANCEMENT OF ARBOVIRAL TRANSMISSION BY MOSQUITOES?
Jefferson A. Vaughan1, Jeffrey A. Bell1, Christina M. Brewer1,
Vasyl V. Tkach1, Hassan K. Hassan2, Thomas R. Unnasch2,
Michael J. Turell3
1
University of North Dakota, Grand Forks, ND, United States, 2University of
Alabama, Birmingham, AL, United States, 3United States Army Medical
Research Institute for Infectious Diseases, Fort Detrick, MD, United States
881
876
POLYMORPHISM IN THE GENE ENCODING GAMBICIN AND
PLASMODIUM FALCIPARUM INFECTION SUSCEPTIBILITY IN
ANOPHELES GAMBIAE
Rodrigo Gonzalez-Cerdas1, Michelle M. Riehle2, Kenneth D.
Vernick2, Jen Hume1, Jose Ribeiro1, Tovi Lehmann1
IDENTIFYING THE GEOGRAPHICAL CONVERGENCE OF
ANOPHELES AND PLASMODIUM
Desmond H. Foley, Leopoldo M. Rueda, Richard C. Wilkerson
Walter Reed Army Institute of Research, Suitland, MD, United States
1
Health, Bethesda, MD, United States, 2Center for Microbial and Plant
Genomics and Department of Microbiology, University of Minnesota, St.
Paul, MN, United States
(ACMCIP Abstract)
179
Department of Ecology and Evolionary Biolology, Yale University, New
Haven, CT, United States, 2Organisation de Coordination pour la Lutte
Contre les Endémies en Afrique Centrale, Yaounde, Cameroon
Detailed Program
www.astmh.org
882
887
GENETIC POPULATION STRUCTURE IN THE MALARIA VECTOR
ANOPHELES MARAJOARA IN NORTHEASTERN SOUTH
AMERICA
A NEW ISOLATE OF BACILLUS THURINGIENSIS SUBSP.
ISRAELENSIS HIGHLY EFFECTIVE AGAINST ANOPHELES
GAMBIAE, AEDES AEGYPTI AND CULEX PIPIENS
Jan E. Conn1, Cong Li2, Marinete M. Povoa3, Maria Anice Sallum4,
Jose Bento Lima5, Richard C. Wilkerson6
Mohamed Ibrahim, Lee A. Bulla
Biological Targets, Inc., Pilot Point, TX, United States
1
Wadsworth Center, New York State Department of Health, Slingerlands,
NY, United States, 2Department of Entomology, Division of Communicable
Diseases and Immunology, Walter Reed Army Institute of Research, Suitland,
MD, United States, 3Programa de Pesquisas em Malaria, Instituto Evandro
Chagas, Belem, Brazil, 4Departamento de Epidemiologia, Universidade de
Sao Paulo, Sao Paulo, Brazil, 5Departamento de Entomologia, Fundacao
Oswaldo Cruz, Rio de Janeiro, Brazil, 6Department of Entomology, Division
of Communicable Diseases and Immunology, Walter Reed Army Institute of
Research, Suitland, MD, United States
888
SPATIOTEMPORAL RISK PATTERNS AND ECOEPIDEMIOLOGY
OF WEST NILE VIRUS DISEASE, COLORADO, 2002-2006
Anna M. Winters1, Chester G. Moore1, Andrew M. Meyer1, W.
John Pape2, Lars Eisen1
1
883
MORTALITY DECELERATION IN LABORATORY REARED, ADULT
ANOPHELES STEPHENSI MOSQUITOES
Jefferson A. Vaughan1, Jeffrey A. Bell1, Robert H. Zimmerman2
1
University of North Dakota, Grand Forks, ND, United States, 2FMEL,
University of Florida, Vero Beach, FL, United States
884
Colorado State University, Fort Collins, CO, United States, 2Communicable
Disease Program, Colorado Department of Public Health and Environment,
Denver, CO, United States
889
A NOVEL LETHAL TRAP FOR GRAVID AEDES AEGYPTI AND
AEDES ALBOPICTUS
Charles Apperson1, Darek Czokajlo2, Philipp Kirsch2, Luma Abu
Ayyash1, Dawn Wesson3, Coby Schal1
1
RISK FACTORS FOR THE PRESENCE OF AEDES AEGYPTI IN
LIMA, PERU
Carmen Flores-Mendoza1, Fernando Chapilliquen2, Luis Cubillas3,
Walter Leon4, Pablo Villaseca4, Fanny Castro1, Juan Perez1, Ruth
Centeno1, Karyn Cruz5, Julio Lacma5, Cecilia Montes-Jave6, Willy
Lescano1, David Florin1
1
2
U.S. Naval Medical Research Center Detachment, Lima, Peru, Direccion
General de Epidemiologia, Ministerio de Salud, Peru, 3Direccion General de
Salud Lima Norte, Ministerio de Salud, Peru, 4Instituto Nacional de Salud,
Lima, Peru, 5Universidad Nacional Federico Villareal, Lima, Peru, 6Naval
Medical Research Center Detachment, Lima, Peru
885
IMMUNE RESPONSIVE SERINE PROTEASE FROM ANOPHELES
GAMBIAE PROMOTES PLASMODIUM FALCIPARUM DEVELOPMENT
Janneth Rodrigues, Carolina Barillas-Mury
886
BLOOD MEAL PREFERENCE AND ISOLATION OF ALPHAVIRUSES AND FLAVIVIRUSES FROM MOSQUITOES IN THE CAUCA
VALLEY, COLOMBIA, SOUTH AMERICA
Ian Mendenhall1, Carlos Valderamma2, Richard JohnstonGonzalez3, William Cardona2, Olga Barón4, Dawn Wesson1,
Clara Ocampo4
1
Tulane University - School of Public Health and Tropical Medicine, New
Orleans, LA, United States, 2Wildlife Conservation Society, Cali, Colombia,
3
Calidris, Cali, Colombia, 4Centro Internacional de Entrenamiento e
Investigaciones Médicas, Cali, Colombia
North Carolina State University, Raleigh, NC, United States, 2APTIV, Inc.,
Portland, OR, United States, 3Tulane University, New Orleans, LA, United
States
890
DETECTING WUCHERERIA BANCROFTI IN AEDES POLYNESIENSIS MOSQUITOES FROM AMERICAN SAMOA: A COMPARISON
OF PCR WITH HAEMALUM STAINING AND DISSECTION
Eric W. Chambers1, Melissa F. Avery1, Mark A. Schmaedick2,
Patrick J. Lammie1, Thomas R. Burkot1
1
Atlanta, GA, United States, 2Division of Community and Natural Resources,
American Samoa Community College, Pago Pago, American Samoa
891
INFLUENCE OF MAIZE POLLEN ON ANOPHELES PRODUCTIVITY
AND MALARIA TRANSMISSION DYNAMICS
Richard J. Pollack1, Rebecca M. Robich1, Anthony E. Kiszewski1,
Asnakew Kebede2, Yemane Ye-Ebiyo3, Afework T. Hailemariam4,
Michael DiBlasi2, James McCann2, Andrew Spielman1
1
Harvard School of Public Health, Boston, MA, United States, 2Boston
University, Boston, MA, United States, 3Center for National Health
Development in Ethiopia, Addis Ababa, Ethiopia, 4Federal Ministry of Health,
Addis Ababa, Ethiopia
892
USE OF FREE MAPPING TOOLS TO SUPPORT THE DEVELOPMENT OF A LOCAL DENGUE INFORMATION SYSTEM
Darwin Elizondo-Quiroja, Saul Lozano-Fuentes, Barry Beaty,
Lars Eisen
180
893
PRELIMINARY ANALYSIS OF SPATIAL PATTERNS OF DENGUE
ACTIVITY IN THREE STATES IN MEXICO
Saul Lozano-Fuentes1, Darwin Elizondo-Quiroja1, Jose Farfan-Ale2,
Maria Alba Lorono-Pino2, Ildefonso Fernandez-Salas3, Julian GarciaRejon2, Maria del Rosario Najera-Vazquez4, Salvador Gomez-Carro4,
Marco Dominguez-Galera5, Pedro Mis-Avila5, Jose Joaquin
Calderon-Martinez5, Barry Beaty1, Lars Eisen1
1
Colorado State University, Fort Collins, CO, United States, 2Univesidad
Autonoma de Yucatan, Merida, Mexico, 3Universidad Autonoma de Nuevo
Leon, Monterrey, Mexico, 4Servicios de Salud Yucatan, Merida, Mexico,
5
Servicios de Salud Quintana Roo, Chetumal, Mexico
894
PROFILE OF MOSQUITO LARVAL HABITATS IN URBAN
PUNTARENAS, COSTA RICA
Adriana Troyo1, Olger Calderon-Arguedas2, Adrian Avendaño2,
Mayra E. Solano2, Douglas O. Fuller1, John C. Beier1
Other Bacterial Infections
899
PHYSICAL, CHEMICAL AND MICROBIAL CHARACTERIZATION
OF SOME LOCALLY MANUFACTURED CANNED TUNA IN OIL
EXPOSED TO THE SUN FOR A LONGER PERIOD
Miriam A. Sagoe1, Kofi Essel2
1
Noguchi Memorial Institute for Medical Research, Accra, Ghana, 2Food and
Drugs Board, Accra, Ghana
900
THE ANTIBIOTIC SUSCEPTIBILITY RATES IN THE GRAM
NEGATIVE BACILLI GROWING IN URINE CULTURES AND THE
PRESENCE OF EXTENDED SPECTRUM BETA LACTAMAZ (ESBL)
Sukran Kose, Derya Tumer, Gulgun Akkoclu
Tepecik Research and Educational Hospital, Izmir, Turkey
901
1
895
ITN INTERVENTIONS ACROSS ENVIRONMENTAL AND TRANSMISSION SETTINGS: THE FUNDAMENTAL ROLE OF SPATIAL
CONNECTIVITY IN DETERMINING EFFECTIVENESS
Manish A. Desai1, Joseph N. Eisenberg2
BARTONELLA SP. INFECTION OF RED-BACKED VOLES
TRAPPED FROM AN INTERIOR ALASKAN SITE WHERE TICKS
ARE ABSENT
Kotaro Matsumoto1, Joseph A. Cook2, Heidi K. Goethert1,
Sam R. Telford1
1
States, 2University of New Mexico Museum, Albuquerque, NM, United
States
1
University of California at Berkeley, Berkeley, CA, United States, 2University
of Michigan, Ann Arbor, MI, United States
896
LANDSCAPE CHARACTERIZATION OF ANOPHELINE LARVAL
HABITATS IN MAPANZA, ZAMBIA
Julie Clennon1, Aniset Kamanga2, Philip Thuma2, Sungano
Mharakurwa2, Clive Shiff1, Christen Fornadel1, Douglas Norris1,
Gregory Glass1
1
States, 2The Malaria Institute at Macha, Choma, Zambia
897
EFFICACY OF VECTOBAC WG, A BACILLUS THURINGIENSIS
ISRAELENSIS FORMULATION, TO CONTROL DENGUE
MOSQUITO VECTORS IN CAMBODIA
To Setha1, Ngan Chantha1, Doung Socheat1, Seleena Benjamin2
1
National Malaria Center, Ministry of Health, Phnom Penh, Cambodia,
Valent BioSciences Corporation, Kuala Lumpur, Malaysia
2
902
A FATAL OUTCOME TREATING PLEURAL TUBERCULOSIS: IS
TREATMENT WORSE THAN THE DISEASE?
Tariq A. Khan, Deborah Asnis, Sumathi Kemisetti
903
BACTERIAL CONTAMINATION IN CEBICHE PURCHASED FROM
RESTAURANTS AND STREET VENDORS IN LIMA, PERU:
PRELIMINARY RESULTS
Victor E. Gonzaga1, Andrés G. Lescano1, Margarita Molina2,
William E. Oswald3, Ana I. Gil2, Claudia F. Lanata2, Héctor H.
Garcia4, David L. Blazes1
1
Naval Medical Research Center Detachment (Naval Medical Research Center
Detachment), Lima, Peru, 2Instituto de Investigación Nutricional, Lima, Peru,
3
Universidad Peruana Cayetano Heredia, Lima, Peru, 4Department of
Microbiology, School of Sciences, Universidad Peruana Cayetano Heredia,
Lima, Peru
898
EFFECTS OF RESIDUAL DOMICILIARY SPRAYINGS WITH
PYRETROIDS ON POPULATIONS OF LUTZOMYIA SPP. IN AN
ENDEMIC AREA OF CARRION’S DISEASE, IN THE NORTHERN
FOREST OF PERU
904
RAPID AND SPECIFIC DIAGNOSTICS OF RICKETTSIAL INFECTIONS BY A PCR-BASED HYBRIDIZATION CHIP ASSAY
Roman Wölfel, Gerhard Dobler
Bundeswehr Institute of Microbiology, Munich, Germany
Mario Troyes1, Nelson Solorzano2, Paul E. Pachas3, Carlos Ticona4,
Fernando Chapilliquen3, Victor Arenas4, Roberto Fernandez5
1
Jaen Directorate of Health, Cajamarca Department, Peru, 2Caraz Hospital,
Ancash Department, Peru, 3General Directorate of Epidemiology-Ministry of
Health, Lima, Peru, 4San Ignacio Health Center, Cajamarca Department,
Peru, 5Naval Medical Research Center Detachment, Lima, Peru
181
University of Miami, Coral Gables, FL, United States, 2Universidad de Costa
Rica, San Jose, Costa Rica
www.astmh.org
Detailed Program
www.astmh.org
905
911
CLASS-SPECIFIC ANTIBODY RESPONSES IN HUMAN
BRUCELLOSIS
HUMAN BRUCELLA ABORTUS INFECTION IN THAILAND: A
REPORT OF THE FIRST TWO CASES
Hind I. Shaheen, Hanan I. El-Mohamady, Sylvia Ghabour, Mathew
Weiner, Isabelle Nakhlla, Adam Armstrong
Somsak Thamthitiwat1, Teerasak Chuxnum2, Henry C. Baggett1,
Kumnuan Ungchusak2, Leonard F. Peruski1, Possawat Jorakate1,
Sathapana Naorat1, Monaya Ekgatat3, Piyada Wangrungsarb4,
Susan A. Maloney1
U.S. Naval Medical Research Unit-3, Cairo, Egypt
906
CASE REPORT: TRAVELER’S BRUCELLA- SPECIFIC IGA
AND IGM ANTIBODIES AS EARLY SERODIAGNOSTIC
MARKERS OF INFECTION
1
International Emerging Infections Program, Nonthaburi, Thailand, 2Bureau
of Epidemiology, Ministry of Public Health, Nonthaburi, Thailand, 3National
Institute of Animal Health, Department of Livestock Development, Bangkok,
Thailand, 4National Institute of Health, Ministry of Public Health,
Nonthaburi, Thailand
Hanan Mohamady, Hind I. Shaheen, John Klena, Isabelle Nakhla,
Mathew Weiner, Adam Armstrong
US NAval Medical Research Unit-3, Cairo, Egypt
907
CASE REPORT OF SALMONELLA TYPHI INFECTION IN A U.S.
TRAVELER
912
A MOUSE DERMAL MODEL TO STUDY EARLY INNATE
IMMUNE EVENTS IN THE SKIN AFTER TRANSMISSION OF
YERSINIA PESTIS
Christopher F. Bosio, Clayton O. Jarrett, B. Joseph Hinnebusch
Rocky Mountain Laboratories, Hamilton, MT, United States
Mohammed O. Shareef, Gulvahid Shaikh, Tabassum Yasmin
913
Nassau University Medical Center, East Meadow, NY, United States
908
ACUTE INFECTION CAUSED BY A NOVEL BARTONELLA
SPECIES: DESCRIPTION OF THE FIRST THREE HUMAN CASES
OF B. TAMIAE -THAILAND
DEVELOPMENT OF REAL-TIME PCR ASSAYS FOR DETECTION
AND CHARACTERIZATION OF BARTONELLA SPECIES IN
HUMAN AND RODENT BLOOD SAMPLES FROM THAILAND
James M. Colborn, Michael Y. Kosoy
Henry C. Baggett1, Michael Kosoy2, Saithip Sutthirattana1, Anussorn
Sitdhirasdr3, Christina Morway2, Kelly Sheff2, Scott F. Dowell4, Susan
Maloney1, Tamara L. Fisk5, Ying Bai2, Leonard Peruski1
Pneumonia and Respiratory Infections
914
1
International Emerging Infections Program, Thailand Ministry of Public
Health-U.S. Centers for Disease Control and Prevention Collaboration,
Nonthaburi, Thailand, 2Centers for Disease Control and Prevention, Fort
Collins, CO, United States, 3Thailand Ministry of Public Health, Nonthaburi,
Thailand, 4Centers for Disease Control and Prevention, Atlanta, GA, United
States, 5Emory University School of Medicine, Atlanta, GA, United States
909
THE DEVELOPMENT OF AN AGE-STRUCTURED MODEL FOR
TRACHOMA TRANSMISSION DYNAMICS AND CONTROL
Manoj Gambhir
Imperial College London, london, United Kingdom
910
PREVALENCE OF BACTERIAL ISOLATES FROM BLOOD CULTURES OF INFANTS ATTENDING PADIATRIC WARDS IN UNIVERSITY OF BENIN TEACHING HOSPITAL, BENIN CITY, NIGERIA
ECONOMIC BURDEN OF COMMUNITY ACQUIRED
PNEUMONIA IN CHILDREN LESS THAN FIVE YEARS
OLD IN EGYPT
Mohamed A. Azab
NAMRU-3, Cairo, Egypt
915
COMMUNITY-ACQUIRED NON-TYPHOIDAL SALMONELLA BACTEREMIA AND PATTERNS OF ANTIMICROBIAL RESISTANCE IN
THAILAND, 2005-2007
Prasert Salika1, Leelaowadee Sangsuk2, Possawat Jorakate1, Anek
Kaewpan1, Wanna Wongjindanon1, Surang Dejsirilert2, Somsak
Thamthitiwat1, Henry Baggett1, Susan Maloney1, Leonard Peruski1
1
International Emerging Infections Program, Bangkok, Thailand, 2Ministry of
Public Health, Bangkok, Thailand
916
Francis Oronsaye
University of Benin School of Medicine, Benin City, Edo State, Nigeria
TOWARDS RAPID DIAGNOSIS OF PULMONARY TUBERCULOSIS
IN MALAWIAN PRISONS
Mwai Makoka
University of Malawi College of Medicine, Blantyre, Malawi
182
917
GROUP A STREPTOCOCCUS PHARYNGITIS AMONG
SCHOOLCHILDREN IN BAMAKO, MALI
Mahamadou M. Keita1, Samba O. Sow1, Boubou Tamboura1,
Melissa Rosenberg2, Milagritos D. Tapia2, Mariam Samake1, James
Dale3, Karen L. Kotloff2
1
3
University of Tennessee, Memphis, TN, United States
2
Viruses - Other
924
PERFORMANCE EVALUATION OF SURVEILLANCE AND RAPID
RESPONSE TEAMS IN THAILAND
Prabda Prapasiri1, Wiput Phoolchareon2, Yaowaluk
Ngoenwiwatkul3
1
Centers for Disease Control and Prevention/IEIP, Nonthaburi, Thailand, 2Thai
Health Policy Foundation, Bangkok, Thailand, 3Faculty of Dentistry, Mahidol
University, Bangkok, Thailand
918
ETIOLOGY OF COMMUNITY-AQIURED PNEUMONIA IN
EGYPTIAN CHILDREN LESS THAN FIVE YEARS OLD
Fouad G. Youssef
www.astmh.org
925
ETIOLOGIES OF ACUTE FEBRILE ILLNESS IN BISHKEK,
KYRGYZSTAN
Sam Yingst1, Kalya Kasymbekova2, Emad Mohareb1, Magdi Saad1,
Marshall Monteville1
919
CORRELATION OF HYPERHOMOCYSTEINEMIA AND
CHLAMYDIA PNEUMONIAE IGG SEROPOSITIVITY WITH CORONARY ARTERY DISEASE IN A GENERAL POPULATION
1
NAMRU-3, Cairo, Egypt, 2Department of State Sanitary and Epidemiological
Service, Bishkek, Kyrgyzstan
926
Katayoun Vahdat, Seyed Mojtaba Jafari
MOSQUITO FEEDING PREFERENCE FOR COLD-BLOODED VERTEBRATES IN ALABAMA
Professor Haghighi Department of Tropical Medicine, The Persian Gulf
Health Research Center/Bushehr University of Medical Sciences, Bushehr,
Islamic Republic of Iran
Gregory S. White1, Hassan K. Hassan1, Sean Graham2, Craig
Guyer2, Thomas R. Unnasch1
920
DELETION OF CD36 CONFERS PROTECTION AGAINST
MYCOBACTERIAL INFECTION
1
University of Alabama at Birmingham, Birmingham, AL, United States,
Auburn University, Auburn, AL, United States
2
927
Xioaming Li, Michael T. Hawkes, Maryanne Crockett, Angelina
Diassiti, Jun Liu, Kevin Kain
THE MINIMAL DOMAIN OF THE EASTERN EQUINE ENCEPHALITIS VIRUS CAPSID NECESSARY FOR INHIBITION OF HOST GENE
EXPRESSION IS REQUIRED FOR VIRAL PATHOGENESIS
McLaughlin-Rotman Centre for Global Health, Departments of
Medicine and Medical Genetics and Microbiology, University of Toronto,
Toronto, ON, Canada
Patricia V. Aguilar1, Lawrence W. Leung1, Eryu Wang2, Scott C.
Weaver2, Christopher F. Basler1
921
LEGIONELLA PREVALENCE IN SPRING RECREATION AREAS OF
TAIWAN
Bing-Mu Hsu1, Puo-Hua Ma1, Chien-Shien Chen2
1
National Chung Cheng University, Chia-Yi, Taiwan, 2Tatung University,
Taipei, Taiwan
922
1
Mount Sinai School of Medicine, New York, NY, United States, 2University
of Texas Medical Branch, Galveston, TX, United States
928
EVALUATION OF THE AOTUS NANCYMAE NEW WORLD MONKEY AS AN ANIMAL MODEL FOR EASTERN EQUINE
ENCEPHALITIS
Benjamin J. Espinosa1, Scott C. Weaver2, Slodovan Paessler2,
Douglas Brinning2, Milagros Salazar1, Tadeusz Kochel1
1
PIRFENIDONE AS ADJUNCTIVE THERAPY PROVIDES SURVIVAL
ENHANCEMENT IN A LETHAL MURINE MODEL OF SYSTEMIC
STREPTOCOCCUS PNEUMONIAE
Edgar M. Musie
U.S. Naval Medical Research Center Detachment, Lima, Peru, 2UTMB Center
for Biodefense and Emerging Infectious Diseases, University of Texas Medical
Branch, TX, United States
(ACMCIP Abstract)
929
923
IN VIVO AND IN VITRO EFFICACY OF TA-18 AGAINST
HANTAVIRUS INFECTION
Qianjun Li1, Dong Hoon Chung1, Yong-Kyu Chu1, Sidath
Kumarapperuma2, Yanjie Sun1, Jeffery Arterburn2, William Parker1,
Colleen Jonsson1
1
Southern Research Institute, Birmingham, AL, United States, 2New Mexico
State University, La Cruses, NM, United States
CO-CIRCULATION OF TWO DIFFERENT HANTAVIRUSES IN A
HECTARE SIZED MARK-RECAPTURE SITES IN INTERIOR
ATLANTIC FOREST IN PARAGUAY
Yong-Kyu Chu1, Robert Owen2, Douglas Goodin3, Linda Allen4,
Colleen Jonsson1
1
Southern Research Institute, Birmingham, AL, United States, 2Department
of Biological Sciences, Texas Tech University, Lubbock, TX, United States,
3
Department of Geography, Kansas State University, Manhattan, KS, United
States, 4Department of Mathematics and Statistics, Texas Tech University,
Lubbock, TX, United States
183
NAMRU-3, Cairo, Egypt
Detailed Program
www.astmh.org
930
Mid-Day Session 129
SEROLOGICAL EVIDENCE FOR URBAN TRANSMISSION OF
VENEZUELAN EQUINE ENCEPHALITIS (VEE) VIRUS IN THE
IQUITOS, CITY, PERU
Career Issues: Global Health Research in the
Tropical Developing World
A. C. Morrison, C. Rocha, R. Carrión, H. Astete, V. Lopez, K.
Escobedo, C. Caray, Dominique Eza, A. Huaman, J. M.
Montgomery, Tadeusz Kochel
Wednesday, November 7, 2007 12:15 p.m. - 1:15 p.m.
Salon CD
931
MOLECULAR EPIDEMIOLOGY OF HUMAN HERPESVIRUS 8 IN
HIV-POSITIVE PATIENTS WITH KAPOSI’S SARCOMA ATTENDED
IN RIBEIRÃO PRETO, BRAZIL
Paula R. Machado, Kleber J. Farias, Luiza A. Castro,
Benedito A. Fonseca
A one-hour panel discussion featuring speakers from the previous session
discussing three big questions: What do you wish you had known before
you started working with your colleagues in a developing world research
setting? What could a little more flexibility — in time, money or resources —
let you do that you might otherwise not be able? What are your career concerns as you face (and have faced) the milestones and expected benchmarks
of faculty advancement?
A light lunch will be provided.
School of Medicine of Ribeirão Preto, Ribeirão Preto, S.P., Brazil
932
CHAIR
PHYLOGEOGRAPHIC DIVERSITY OF COLORADO SIN NOMBRE
VIRUS STRAINS
Mark T. Hughes, Jeffrey B. Doty, Charles H. Calisher, Barry J. Beaty
MODERATOR
Robert Gilman
United States
933
PREVENTING PERSON TO PERSON TRANSMISSION OF NIPAH
VIRUS: CULTURAL CONTEXT
1
1
2
1
Rasheda Khan , Nazmun Nahar , Lauren Blum , M. J. Hossain ,
Emily S. Gurley1, Stephen Luby1
1
ICDDRB, Dhaka, Bangladesh, 2United States Agency for International
Development, Kinshasa, Democratic Republic of the Congo
12:15 p.m.
PANELIST
Danny A. Milner
The Brigham & Women’s Hospital, Boston, United States
12:30 p.m.
PANELIST
Poster Session C ACMCIP Abstracts – Molecular,
Cellular and Immunoparasitology
727, 775, 780, 785, 789, 792, 798, 799, 800, 801, 82, 84, 86, 88,
823, 824, 825, 826, 827, 828, 831, 846, 855, 857, 858, 859, 860,
861, 862, 876, 928
Risa Hoffman
UCLA School of Medicine, Los Angeles, United States
12:45 p.m.
PANELIST
Regina LaRocque
Brigham and Women’s Hospital, Boston, United States
Burroughs Wellcome Fund – ASTMH
Fellowship Committee Meeting
1 p.m.
Room 336
Mina Hosseinipour
Wednesday, November 7, 2007 Noon – 2 p.m.
University of North Carolina School of Medicine, Chapel Hill, NC, United
States
PANELIST
Room 410
Wednesday, November 7, 2007 12:15 p.m. – 1:15 p.m.
184
PubMed and HINARI: Searching and Getting the
Articles You Want
12:20 p.m.
USE OF GEOGRAPHIC INFORMATION SYSTEM (GIS) IN
SCIENCE TODAY
James Higgins
Salon F
ESRI, Chesterbrook, PA, United States
12:35 p.m.
PubMed is a Web interface enabling the users to search MEDLINE, the U.S.
National Library of Medicine’s premier bibliographic database covering the
fields of medicine, nursing, dentistry, veterinary medicine, the health care
system and the preclinical sciences. Health InterNetwork is a partnership
between the World Health Organization and several major biomedical publishers providing registered institutions in certain developing countries free
full text access to more than 3680 scientific journals. Attendees will learn
the basics and some advanced techniques of searching PubMed and retrieving the full text article online through PubMed free full text filter, PubMed
Central and especially HINARI. Also, saved search strategies and automated
e-mail updates with links to full text for HINARI via MyNCBI will be introduced. http://www.who.int/hinari/ and http://www.pubmed.gov/.
TEACHERS DOMAIN AT WGBH EDUCATION FOUNDATION
SPEAKER
ANIMATION IN BIOLOGICAL SCIENCES
Chuong Huynh
David Bolinsky
Nationa Institutes of Health, Bethesda, MD, United States
xVIVO, Rochy Hill, CT, United States
Mid-Day Session 131
Mid-Day Session 132
Scientists Making Media: How Do We Do It?
National Institutes of Health Grants: Grantsmanship,
Review and Funding Opportunities
Salon G
This symposium will bring together experts in the field of video and animation production for biological sciences and real life documentaries. In a new
era of visual resources for learning and publishing, scientists are not aware
of ways of illustrating, animating or videomaking. Major scientific journals,
institutes of research and universities are using visual means of propagating
knowledge. But there are scarce federal funding resources available to do
these kinds of productions, despite the needs. In this symposium we will get
an idea of where and how to find resources to create our own videos and
how to best use them for educational purposes. Also, how public TV has
created major open source materials for science educators and how much
more it could be done to synchronize science research and society will be
examined. Finally, the session will explore how Geographic Information
System (GIS) is implemented in science and highlight two examples of
media production: animation and documentaries to the service science.
Denise Blumenthal
WGBH, Boston, MA, United States
12:50 p.m.
DOCUMENTARIES AND ACADEMIA
Calogero Salvo
Salvo Production, NY, United States
1 p.m.
Salon KL
Tailored to the interests of young investigators, this session will focus on
identifying funding opportunities, the art of competitive grant-writing, and
the peer-review process at the National Institutes of Health.
CHAIR
John C. Pugh
SPEAKERS
Lawrence Bergman
Alexander Politis
CHAIR
Irene Bosch
Martin John Rogers
UMASS Medical School, Worcester, MA, United States
12:15 p.m.
INTRODUCTION
Irene Bosch
185
Mid-Day Session 130
www.astmh.org
www.astmh.org
Detailed Program
Mid-Day Session 132A
Workers in Tropical Medicine Video: Karl M. Johnson,
MD: Life and Legend of a Leader in Tropical Virology
Franklin Hall B
1:30 p.m. - 7 p.m.
Franklin 1
Symposium 135
This 60-minute film presents an interview of Dr. Karl Johnson, focusing on
his career in tropical medicine. The interview was conducted by Barnett L.
Cline, MD, PhD.
A Multi-Faceted Investigation of an Outbreak of Rift
Valley Fever in Kenya, 2006-2007 - Part I
CHAIR
Salon AB
Barnett Cline
An outbreak of Rift Valley Fever, causing severe illness in more than 600
people and resulting in more than 150 deaths, occurred in several locations
in Kenya from November 2006 until early March 2007. The symposium will
review the epidemic and present findings from the multi-faceted investigation which included epidemiologic and clinical investigations, economic
impact, entomologic surveys, virologic/genetic studies, veterinary surveillance
and will include geographic modeling incorporating data from the above
studies in combination with satellite imagery providing moisture and soil
information. The focus ultimately will be on what information was collected,
which will enable public health officials to forecast future outbreaks in order
to implement effective public health prevention measures before an outbreak occurs (including the potential for livestock immunization, targeted
larvacidal campaigns and behavior modification/risk reduction)
DIRECTOR AND PRODUCER
Patrick Dunavan
HealthQuest Media Inc., Los Angeles, CA, United States
Meet the Professors E: International Travel to Give or
Receive Health Care
Franklin 3/4
CHAIR
This session will explore issues in medical tourism, such as seeking health
care abroad and traveling to provide medical care.
Robert Breiman
CHAIR
Tom Ksiazek
Anne McCarthy
Centers for Disease Control and Prevention Atlanta, GA, United States
Centers for Disease Control and Prevention-KEMRI, Nairobi, Kenya
1:30 p.m.
12:15 p.m.
THE 2006-2007 OUTBREAK
MEDICAL TOURISM: EPIDEMIOLOGY OF SEEKING HEALTH
CARE ABROAD
David Mutonga
Christie Reed
Ministry of Health, Nairobi, Kenya
1:50 p.m.
FINDINGS FROM RISK FACTOR STUDIES IN HUMANS
12:30 p.m.
Hannah Gould
MEDICAL TOURISM: TRAVELING TO PROVIDE MEDICAL CARE
Anne McCarthy
2:05 p.m.
FINDINGS FROM RISK FACTOR STUDIES IN HUMANS
12:45 p.m.
Eileen Farnon
ACCREDITATION OF HOSPITALS WORLDSIDE AND PATIENT
SAFETY SOLUTIONS
David Jaimovich
2:20 p.m.
Joint Commission International, Chicago, IL, United States
VETERINARY FINDINGS OF THE OUTBREAK
R.M. Murithi
1 p.m.
CONCLUSION AND QUESTIONS
Ministry of Livestock and Fisheries Development, Nairobi, Kenya
Anne McCarthy
2:45 p.m.
ENTOMOLOGIC FINDINGS
Rosemary Sang
Kenya Medical Research Institute, Nairobi, Kenya
186
Symposium 136
www.astmh.org
1:30 p.m.
934
Salon CD
Neglected tropical diseases, occurring primarily in developing countries and
associated with limited economic resources, remain serious social problems
despite improved treatments and public health interventions. Development
of effective vaccination strategies may result in disease eradication, but is
limited by available science, immunology and financial resources. This symposium will introduce the science of vaccines and their potential uses in several neglected diseases of the tropics.
ARTEMISININ RESISTANCE IN CAMBODIA?
Harald Noedl1, Lon Chan Thap2, Youry Se1, Duong Socheat2, Sok
Peou2, Kurt Schaecher1, Sabaithip Sriwichai1, Paktiya TejaIsavadharm1, Bryan Smith1, Krisada Jongsakul1, Sittidech Surasri1,
Mark M. Fukuda1
1
the Medical Science, Bangkok, Thailand, 2National Center for Parasitology,
Entomology and Malaria Control, Phnom Penh, Cambodia
1:45 p.m.
935
CHAIR
M. Patricia Joyce
Peter J. Hotez
1:30 p.m.
HOOKWORM VACCINES
Peter J. Hotez
A HIGH THROUGHPUT IN VITRO IC50 ASSAY FOR
PLASMODIUM FALCIPARUM FIELD SAMPLES: ADAPTATION OF
A DAPI ASSAY
Daouda Ndiaye1, Mary Lynn Baniecki2, El-Hadji Badiane1, Moussa
Dieng Sarr3, Omar Ndir1, Souleymane Mboup1, Johanna Daily2,
Dyann Wirth2
1
Cheikh Anta Diop University, Dakar, Senegal, 2Harvard School of Public
Health, Boston, MA, United States, 3Service de Lutte antiparasitaire de Thies
(S.L.A.P), Thies, Senegal
2 p.m.
936
1:55 p.m.
SCHISTOSOMIASIS VACCINES
MODELLING ANTIMALARIAL DRUG RESISTANCE AMD THE
COST-EFFECTIVENESS OF DIFFERENT COVERAGE RATES WITH
ARTEMISININ COMBINATION THERAPIES (ACTS)
2:20 p.m.
Shunmay Yeung1, Wirichada Pongtavornpinyo1, Ian M. Hastings2,
Anne Mills3, Nicholas J. White1
Alex Loukas
LEPROSY VACCINES
M. Patricia Joyce
2:50 p.m.
1
Oxford-Mahidol Tropical Medicine Programme, Bangkok, Thailand,
Liverpool School of Tropical Medicine, Liverpool, United Kingdom, 3London
School of Hygiene and Tropical Medicine, London, United Kingdom
2
2:15 p.m.
937
BURULI ULCER VACCINES
Kris Huygen
WIV-Pasteur Institute Brussels, Brussels, Belgium
Malaria - Drug Resistance: Modeling and High
Throughput Analysis
Salon E
1:30 p.m. - 3:15 PM
THE IMPACT OF HIV-1 ON THE MALARIA PARASITE BIOMASS
IN SUB-SAHARAN AFRICA AND ITS POSSIBLE CONTRIBUTION
TO THE EMERGENCE AND SPREAD OF ANTIMALARIAL DRUG
RESISTANCE
Jean-Pierre Van Geertruyden1, Joris Menten1, Robert
Colebunders1, Eline Korenromp2, Umberto D’Alessandro1
1
Prince Leopold Instituut voor tropische geneeskunde, Antwerpen, Belgium,
Department of Public Health, University Medical Centre Rotterdam,
Rotterdam, The Netherlands
2
2:30 p.m.
938
CHAIR
Jean Bosco Ouedraogo
Institut de Recherche en Sciences de la Sante, Bobo-Dioualasso,
Burkina Faso
Stephanie G. Valderramos
Albert Einstein College of Medicine, Bronx, NY, United States
RARE DRUG RESISTANCE ALLELES THRIVE IN MOSQUITO
PHASE OF PLASMODIUM FALCIPARUM
Sungano Mharakurwa1, Taida Kumwenda1, Mtawa Mkulama1,
Musapa Mulenga1, Sandra Chishimba1, Jay Sikalima1, Douglas
Norris2, Clive J. Shiff2, Philip E. Thuma1
1
The Malaria Institute at Macha, Choma, Zambia, 2Johns Hopkins Bloomberg
School of Public Health, Baltimore, MD, United States
187
Vaccinology and Neglected Tropical Diseases
Detailed Program
www.astmh.org
2:45 p.m.
2:25 p.m.
939
AMPLIFICATION OF THE PFMDR1 LOCUS IN PLASMODIUM
FALCIPARUM IS LINKED TO PLEIOTROPIC TRANSCRIPTIONAL
REGULATION
Joseph M. Gonzales1, Jigar J. Patel1, Napawan Ponmee2, Lei
Jiang2, Pradip K. Rathod2, Michael T. Ferdig1
1
University of Notre Dame, Notre Dame, IN, United States, 2University of
Washington, Seattle, WA, United States
3 p.m.
SINGLE MOTHERS, SOCIAL RISK AND THE
MANAGEMENT OF CHILDHOOD MALARIA:
CASE STUDY FROM COASTAL TANZANIA
Vinay Kamat
2:45 p.m.
HOUSEHOLD DYNAMICS AND GENDERED RESPONSES TO
CHILDHOOD MALARIA: CASE STUDIES FROM MALI
Amy Ellis
940
MUTANT PFCRT DOES NOT CONFER HIGH LEVELS OF
CHLOROQUINE RESISTANCE TO ALL STRAINS OF
Symposium 138A
Stephanie Valderramos1, Lise Musset2, Juan-Carlos Valderramos2,
David A. Fidock2
VFR: Travel to Visit Friends and Relatives in Developing
Countries
1
Albert Einstein College of Medicine, Bronx, NY, United States, 2Columbia
Salon G
Symposium 138
Gender and the Social Risks of Malaria: Implications for
Malaria Control Strategies in Africa
Salon F
Women and their children disproportionately bear the clinical burden of
malaria and, as a result, most malaria control strategies directly target mothers, pregnant women and children under five. In order to ensure that these
programs are effective, it is essential to consider the ways that sociocultural,
economic and other structural risks interact with biological factors to make
women particularly vulnerable to both the physiological and social burdens
of malaria. In order to illustrate the implications of gendered aspects of
malaria for the development and implementation of effective malaria control strategies, the speakers in this symposium will draw on case studies
from Africa which highlight factors that constrain women’s abilities to adopt
recommended malaria prevention and treatment behaviors.
CHAIR
Amy E. Patterson
1:30 p.m.
RURAL VULNERABILITIES AND ACCESS TO EFFECTIVE
MALARIA TREATMENT: CASE STUDIES FROM KILOMBERO
DISTRICT, TANZANIA
Brigit Obrist
Foreign-born residents comprise 11% of the U.S. population, and when
combined with their U.S.-born spouses and children, comprise an increasing
proportion of U.S. international travelers as they return to visit friends and
relatives (VFR). The majority of diseases, such as malaria, measles and
typhoid are imported into the U.S. by travelers although they are easily prevented, deaths continue to occur. Identification of the barriers to effective
prevention is needed, as well as new strategies to reach both the VFR population and the health care providers who care for them both before and
after travel.
CHAIR
Christie M. Reed
David R. Boulware
1:30 p.m.
THE CHANGING EPIDEMIOLOGY OF U.S. TRAVEL: THE FOREIGN BORN TRAVELER RETURNING HOME
Christie M. Reed
1:50 p.m.
THE IMMIGRANT AS A TRAVELER: HOW DO
WE REACH THEM?
Patricia F. Walker
2:10 p.m.
2 p.m.
THE IMMIGRANT AS A TRAVELER: HOW DO WE PREPARE
THEM AS TRAVELERS?
HEALTHY CROPS OR HEALTHY CHILDREN? WOMEN’S
COMPETING PRIORITIES DURING THE CULTIVATION SEASON
IN RURAL TANZANIA
David R. Boulware
Rene P. Gerrets
New York University, New York, NY, United States
188
www.astmh.org
2:30 p.m.
2:50 p.m.
ASPECTS OF IMMUNIZATIONS FOR VISITING FRIENDS
AND RELATIVES (VFR) TRAVELERS
DENGUE VACCINE CANDIDATES: CURRENT STATUS
Lin H. Chen
GlaxoSmithKline Biologicals, King of Prussia, PA, United States
Bruce Innis
Harvard University, Cambridge, MA, United States
2:50 p.m.
CONCLUSION AND QUESTIONS
David R. Boulware
Mosquitoes - Biochemistry, Molecular Biology and
Molecular Genetics I
Salon IJ
Pathways to Dengue Vaccine Development
Salon H
This symposium will describe the following: 1) the epidemiology of dengue
virus infection; 2) review of burden of illness from eight specific sites; 3)
recent advances in high throughput diagnostics; and 4) status of current
vaccine development.
1:30 p.m. - 3:15 PM
CHAIR
Donald E. Champagne
Sanjeev Kumar
1:30 p.m.
941
CHAIR
Joel Kuritsky
Pediatric Dengue Vaccine Initiative, Seoul, Republic of Korea
A SECRETED ANOPHELES MIDGUT PEROXIDASE REGULATES
PLASMODIUM FALCIPARUM DEVELOPMENT
Harold Margolis
Sanjeev Kumar, Lalita Gupta, Carolina Barillas-Mury
1:30 p.m.
1:45 p.m.
942
INTRODUCTION
Harold Margolis
LOCALIZATION OF NOVEL α-CARBONIC ANYDRASES FROM
THE LARVAE OF ANOPHELES GAMBIAE AND AEDES AEGYPTI
1:40 p.m.
Kristin E. Smith, Leslie A. VanEkeris, Paul J. Linser
BURDEN OF DENGUE INFECTION: A VIEW FROM THE FIELD
Bill Letson
2 p.m.
University of Florida, Saint Augustine, FL, United States
2 p.m.
943
ECONOMIC AND HEALTH BURDEN OF DENGUE IN EIGHT
COUNTRIES
MEMBERS OF THE IMMUNOGLOBULIN SUPERFAMILY
HELP CONTROL MALARIA AND BACTERIA IN ANOPHELES
GAMBIAE MOSQUITOES
Jose Suaya
Lindsey S. Garver, George Dimopoulos
Brandeis University, Waltham, MA, United States
Malaria Research Institute, Johns Hopkins Bloomberg School of Public
Health, Baltimore, MD, United States
2:20 p.m.
SECOND GENERATION DENGUE DIAGNOSTICS
2:15 p.m.
944
Alan Barrett
2:35 p.m.
DENGUE VACCINE CANDIDATES: CURRENT STATUS
PI-3 KINASE AND PTEN: DUELING INSULIN SIGNALING MOLECULES IN THE MOSQUITO AEDES AEGYPTI
Michael A. Riehle, Benjamin M. Pri-Tal, Jessica M. Brown
Jean Lang
sanofi pasteur, Lyon, France
189
Symposium 139
Detailed Program
www.astmh.org
2:30 p.m.
2 p.m.
945
THE HERVES TRANSPOSABLE ELEMENT IN
ANOPHELES GAMBIAE
Ramanand Arun Subramanian1, Tovi Lehmann2,
Peter A. Atkinson3, David A. O’Brochta1
CONSTRUCTION OF A LINKAGE MAP FOR
SCHISTOSOMA MANSONI
Tim Anderson
United States
1
UMBI, Rockville, MD, United States, 2National Institute of Allergy and
States, 3University of California, Riverside, CA, United States
2:25 p.m.
2:45 p.m.
Geoffrey Gobert
946
EPIGENETIC REGULATION OF STACKED TRANSGENE IN
YELLOW FEVER MOSQUITO, AEDES AEGYPTI
Nagaraja Sethuraman Balakathiresan1, Fred Gould2,
David A. O’Brochta1
1
University of Maryland Biotechnology Institute, Rockville, MD, United
States, 2Department of Entomology, College of Agriculture and Life
Sciences, Raleigh, NC, United States
3 p.m.
947
GENE EXPRESSIONAL CHANGES DURING THE SCHISTOSOMA
JAPONICUM LIFECYCLE
2:50 p.m.
PROTEOMIC ANALYSIS OF SCHISTOSOMA MANSONI
EGG SECRETIONS
David Williams
Symposium 142
Progress in Vaccines and Immunotherapy for
Leishmaniasis
ANALYSIS OF THE TRANSCRIPTOME OF AEDES AEGYPTI MALE
REPRODUCTIVE ACCESSORY GLANDS
Liberty AB
Donald E. Champagne, Mark R. Brown
This symposium focuses on advances in the development and clinical application of vaccines and immunotherapy against leishmaniasis. Clinical data
from trials in Africa and South America will be presented using novel vaccines and immunotherapeutic approaches to treat various forms of leishmaniasis, including visceral, post kala-azar dermal, cutaneous and mucosal.
Symposium 141
Schistosome Functional Genomics
CHAIR
Salon KL
Steven G. Reed
This symposium is designed to review and update progress in the effort to
develop genomic and functional genomic tools for schistosomiasis research.
This symposium will describe new functional genomic databases and efforts
to better understand basic parasite biology through linkage mapping,
microarray and proteomic analyses.
1:30 p.m.
INTRODUCTION
Steven G. Reed
CHAIR
David Williams
1:55 p.m.
LEISHMANIA VACCINE DEVELOPMENT
Philip T. LoVerde
Steven Reed
United States
1:30 p.m.
TREATMENT OF LEISHMANIA INFECTION WITH THE TLR 7/8
AGONIST, IMIQUIMOD: FROM MOLECULAR STUDIES TO
HUMAN CLINICAL TRIALS
A NEW FUNCTIONAL GENOMICS DATABASE FOR S. MANSONI
Guilherme C. Oliveira
Fundação Oswaldo Cruz (FIOCRUZ), Belo Horizonte, Brazil
2:15 p.m.
Greg Matlashewski
McGill University, Montreal, QC, Canada
2:35 p.m.
CLINICAL STUDIES IN SUDAN: LEISHMANIA VACCINE
Hashim Ghalib
190
2:55 p.m.
www.astmh.org
2:15 p.m.
CLINICAL DEVELOPMENT OF THE LEISH-111F +
MPL-SE VACCINE
Franco Piazza
952
CYTOKINE RESPONSES TO MALARIAL ANTIGENS AND
ACTIVATION OF TOLL-LIKE RECEPTOR (TLR) MEDIATED
PATHWAYS IN HUMAN CO-INFECTIONS WITH FILARIAL
PARASITES AND MALARIA
Benoit Dembele1, Abhisake Kole2, Abdallah Diallo1, Simon
Metenou2, Siaka Konate1, Yaya Coulibaly1, Husseini Dolo1,
Michel E. Coulibaly1, Lamine Soumaoro1, Thomas B. Nutman2,
Amy Klion2, Cheick Traore1, Siddhartha Mahanty2
Filariasis III - Immunology
Liberty C
1
1:30 p.m. - 3:15 PM
Filariasis Unit, Malaria Research and Training Centre, University of Bamako,
Mali, 2Laboratory of Parasitic Diseases, National Institute of Allergy and
Infectious Diseases, Bethesda, MD, United States
CHAIR
(ACMCIP Abstract)
Siddhartha Mahanty
2:30 p.m.
Manish Ramesh
1:30 p.m.
948
TWO WEEKS OF REPEATED PARASITE EXPOSURES DO NOT
INCREASE THE SUSCEPTIBILITY OF VACCINATED MICE TO
HELMINTH INFECTIONS
953
DEVELOPMENT OF A NEMATODE MICROMOTILITY ASSAY TO
MEASURE KILLING OF FILARIAL PARASITES BY CULEX PIPIENS
PIPIENS MIDGUT TISSUE HOMOGENATE
Sara M. Erickson1, Lyric C. Bartholomay2, Michael J. Kimber2,
Tim A. Day2, Bruce M. Christensen1
1
University of Wisconsin-Madison, Madison, WI, United States, 2Iowa State
University, Ames, IA, United States
Marc P. Hübner, Marina N. Torrero, Edward Mitre
2:45 p.m.
United States
3 p.m.
949
GRANZYME A AND B EXPRESSION IS ASSOCIATED WITH
IMMUNOSUPPRESSION IN HUMAN AND MURINE FILARIASIS
Wiebke Hartmann1, Marlis Badusche1, Markus Simon2, Bernhard
Fleischer1, Simone Korten1
Viruses I
1
2
Metschnikoff Laboratory, Max-Planck-Institut fuer Immunbiologie,
Freiburg, Germany
Franklin 3/4
2 p.m.
CHAIR
950
1:30 p.m. - 3:15 p.m.
Jonathan H. Epstein
MICROFILARIA POSITIVITY MODULATES THE EXPRESSION OF
FCER1-A ON MONOCYTES IN FILARIA-INFECTED PATIENTS
The Consortium for Conservation Medicine, New York, NY, United States
Cathy Steel, Thomas B. Nutman
Johns Hopkins University School of Public Health, Baltimore, MD,
United States
Gregory Glass
191
1:45 p.m.
Detailed Program
www.astmh.org
1:30 p.m.
2:30 p.m.
954
958
THE EMERGENCE OF NIPAH VIRUS IN MALAYSIA:
EPIDEMIOLOGY AND HOST ECOLOGY OF PTEROPUS BATS
PHYLOGENTICALLY DISTINCT HANTAVIRUSES IN SOREX
CINEREUS AND SOREX MONTICOLUS IN THE UNITED STATES
Jonathan H. Epstein1, Sohayati Abdul Rahman2, Craig S. Smith3,
Kim Halpin4, Syed Hassan Sharifah2, Abdul Aziz Jamaluddin5, Hume
E. Field3, Alex Hyatt4, The Henipavirus Ecology Research Group
(HERG)1, Peter Daszak1
Satoru Arai1, Laarni Sumibcay1, Shannon N. Bennett1, Joseph A.
Cook2, Jin-Won Song3, Cheryl Parmenter2, Vivek R. Nerurkar1, Terry
L. Yates2, Richard Yanagihara1
1
The Consortium for Conservation Medicine, New York, NY, United States,
2
The Veterinary Research Institute, Ipoh, Malaysia, 3The Department of
Primary Industries and Fisheries, Yeerongpilly, Australia, 4The Australian
Animal Health Laboratory, Geelong, Australia, 5Department of Veterinary
Services, Kuala Lumpur, Malaysia
1:45 p.m.
955
RECURRENT NIPAH VIRUS OUTBREAKS IN BANGLADESH,
2001-2007
Stephen Luby1, Mahmudur Rahman2, M. J. Hossain1, Be-Nazir
Ahmed2, Emily Gurley1, Shakila Banu1, Nusrat Homira1, Pierre E.
Rollin3, James A. Comer3, Paul Rota3, Joel Montgomery3,
Thomas G. Ksiazek3
1
University of Hawaii, Honolulu, HI, United States, 2University of New
Mexico, Albuquerque, NM, United States, 3Korea University, Seoul, Republic
of Korea
2:45 p.m.
959
THE ROLE OF PREDATORS IN REDUCING PARASITES IN PREY
POPULATIONS: AN EXAMPLE IN URBAN USA
Gregory E. Glass1, Robert D. Holt2, Lynne C. Gardner-Santana1,
Jessica Chen3, Douglas E. Norris1, Sabra L. Klein1, Manojit Roy2,
Robert H. Purcell4
1
International Center for Diarrhoeal Disease Research, B, Dhaka, Bangladesh,
Institute for Epidemiology Disease Control and Research, Dhaka, Bangladesh,
3
The W. Harry Feinstone Department of Molecular Microbiology and
Immunology, The Johns Hopkins University Bloomberg School of Public
Health, Baltimore, MD, United States, 2Department of Zoology, University of
Florida, Gainesville, FL, United States, 3Department of Psychology, The Johns
Hopkins University, Baltimore, MD, United States, 4Laboratory of Infectious
Diseases, National Institute of Allergy and Infectious Diseases, National
Institutes of Health, Bethesda, MD, United States
2 p.m.
3 p.m.
1
2
956
UNDERSTANDING NIPAH VIRUS EMERGENCE IN PENINSULAR
MALAYSIA: THE ROLE OF EPIDEMIC ENHANCEMENT IN
DOMESTIC PIG POPULATIONS
Juliet R. Pulliam1, Jonathan Dushoff2, Hume E. Field3, Jonathan H.
Epstein4, Henipavirus Ecology Research Group (HERG)4, Andrew P.
Dobson5, Peter Daszak4
1
Emory University, Atlanta, GA, United States, 2McMaster University,
Hamilton, ON, Canada, 3Biosecurity Sciences Laboratory, Department of
Primary Industries and Fisheries, Queensland, Australia, 4Consortium for
Conservation Medicine, New York, NY, United States, 5Princeton University,
Princeton, NJ, United States
2:15 p.m.
957
960
OUTBREAK OF FATAL CARDIOPULMONARY FAILURE AMONG
CHILDREN CAUSED BY AN EMERGING STRAIN OF
ENTEROVIRUS 71 - NAKHORN RATCHASIMA PROVINCE,
THAILAND, 2006
Rome Buathong1, Wanna Hanshoaworakul1, Sopon
Iamsirithaworn1, Yoawapa Pongsuwanna2, Pilaipan Puthawathana3,
Michael O’Reilly4, Kumnuan Ungchusak5
1
Field Epidemiology Training Program, Bureau of Epidemiology, Nonthaburi,
Thailand, 2National Institute of Health, Department of Medical Science,
Nonthaburi, Thailand, 3Department of Microbiology, Faculty of Medicine
Siriraj Hospital, Mahidol University, Bangkok, Thailand, 4Thailand Ministry of
Public Health-US Centers for Disease Control and Prevention Collaboration,
Nonthaburi, Thailand, 5Bureau of Epidemiology, Department of Disease
Control, Nonthaburi, Thailand
OUTBREAK OF HUMAN RABIES IN MADRE DE DIOS AND
PUNO, PERU DUE TO CONTACT WITH THE COMMON VAMPIRE
BAT, DESMODUS ROTUNDUS
Coffee Break
Jorge Gomez-Benavides1, C. Manrique1, F. Passara1,
C. Huallpa1, V. A. Laguna2, H. Zamalloa2, S. Recuenco3, A. Diaz3,
A. Velasco-Villa3, M. Niezgoda3, C. Rupprecht3, Tadeusz Kochel2,
J. M. Montgomery2
Franklin Hall B
1
Direccion General de Epidemiologia, Ministerio de Salud, Peru, 2Naval
Medical Research Center Detachment, Lima Peru, 3Centers for Disease
Control and Prevention, Atlanta, GA, United States
192
www.astmh.org
Symposium 145
A Multi-Faceted Investigation of an Outbreak of Rift
Valley Fever in Kenya, 2006-2007 - Part II
Protozoa
Salon AB
3:45 p.m. - 5:30 PM
An outbreak of Rift Valley Fever, causing severe illness in more than 600
people, resulting in more than 150 deaths, occurred in several locations in
Kenya from November 2006 until early March 2007. The symposium (I and
II) will review the epidemic and present findings from the multi-faceted
investigation, which included epidemiologic and clinical investigations, economic impact, entomologic surveys, virologic/genetic studies, veterinary surveillance, and will include geographic modeling incorporating data from the
above studies in combination with satellite imagery providing moisture and
soil information. The focus ultimately will be on what information was collected, which will enable public health officials to forecast future outbreaks
in order to implement effective public health prevention measures before an
outbreak occurs (including the potential for livestock immunization, targeted
larvacidal campaigns and behavior modification/risk reduction)
CHAIR
Robert Breiman
Thomas Ksiazek
Salon CD
CHAIR
Thaddeus Graczyk
Barbara Mann
3:45 p.m.
961
EFFICACY OF PYRVINIUM PAMOATE AGAINST
CRYPTOSPORIDIUM PARVUM INFECTION IN VITRO
AND IN A NEONATAL MOUSE MODEL
Autumn S. Girouard1, David J. Sullivan1, Curtis R. Chong2,
Thaddeus K. Graczyk1
1
United States, 2Johns Hopkins University School of Medicine, Baltimore, MD,
United States
ENTOMOLOGY TESTING: MOLECULAR EPIDEMIOLOGY OF RVF
ISOLATES AND NOVEL ARBOVIRUSES IDENTIFIED
John Lee
Detrick, MD, United States
4:10 p.m.
HUMAN VIROLOGIC AND IMMUNOLOGIC FINDINGS A WINDOW INTO ANTIBODY KINETICS, VIRAL LOAD AND
CLINICAL PRESENTATION
4 p.m.
962
IMPACT OF BATHERS ON LEVELS OF CRYPTOSPORIDIUM
PARVUM OOCYSTS AND GIARDIA LAMBLIA CYSTS IN RECREATIONAL BEACH WATERS
Thaddeus K. Graczyk, Deirdre Sunderland, Leena Tamang,
Patrick N. Breysse
United States
4:15 p.m.
963
M. Kariuki Njenga
4:35 p.m.
FORECASTING RVF OUTBREAKS-FINETUNING A MODEL
Kenneth Linthicum
5 p.m.
A MOLECULAR IN VITRO ASSAY TO ASSESS THE
PARASITOCIDAL ACTIVITY OF TOLTRAZURIL AGAINST
NEOSPORA CANINUM
Bruno Gottstein1, Maria Strohbusch1, Norbert Mueller1,
Andrew Hemphill1, Gisela Greif2
1
Institute of Parasitology, Bern, Switzerland, 2Bayer HelathCare,
Leverkusen, Germany
(ACMCIP Abstract)
SPATIAL MODELING OF THE RVF EPIDEMIC: THE
ROLE OF KENYA-BASED GEOGRAPHIC, GEOLOGIC
AND CLIMATOLOGIC FACTORS
Allen Hightower
Centers for Disease Control and Prevention-Kenya, Nairobi, Kenya
193
3:45 p.m.
Detailed Program
www.astmh.org
4:30 p.m.
964
THE STUDY OF ASSOCIATIONS BETWEEN ENTAMOEBA
HISTOLYTICA INFECTION AND DISEASE WITH SINGLE
NUCLEOTIDE POLYMORPHISMS (SNPS) IN IMMUNE
RESPONSE GENES
Priya Duggal1, Kristine Peterson2, Rashidul Haque3, Dinesh Mondal3,
Alan Sher4, Stacy M. Ricklefs5, Steve Porcella5, William A. Petri2
1
National Human Genome Research Center, National Institute of Health,
Baltimore, MD, United States, 2University of Virginia, Charlottesville, VA,
United States, 3International Centre for Diarrheal Disease Research, Dhaka,
Bangladesh, 4National Institute of Health, National Institute of Allergy and
Infectious Diseases, Bethesda, MD, United States, 5National Institute of
Health, National Institute of Allergy and Infectious Diseases, Rocky Mountain
Laboratories, Hamilton, MT, United States
Malaria - Molecular Markers of Drug Resistance
in the Field
Salon E
3:45 p.m. - 5:30 PM
CHAIR
Qin Cheng
Australian Army Malaria Institute, Brisbane, Australia
Andrea M. McCollum
3:45 p.m.
968
4:45 p.m.
965
THE IMPORTANCE OF IRON IN ANAEROBIC METABOLISM OF
ENTAMOEBA HISTOLYTICA AND ENTAMOEBA INVADENS
Avelina Espinosa, Shannon Arnold
Roger Williams University, Bristol, RI, United States
(ACMCIP Abstract)
Stephane Picot1, Piero L. Olliaro2, Frédérique de Monbrison1,
Pascal Ringwald2
1
University Claude Bernard, Lyon, France, 2World Health Organization,
Geneva, Switzerland
5 p.m.
966
REAL-TIME PCR ASSAY FOR DETECTION OF E. HISTOLYTICA
DNA IN SALIVA AND URINE SPECIMENS OF AMEBIC LIVER
ABSCESS (ALA) PATIENTS
Rashidul Haque1, Mamun Kabir1, Dinesh Mondal1, Shakil
Ahamed1, William A. Petri2
1
International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh,
University of Virginia Department of Medicine, Division of Infectious
Diseases and International Health, Charlottesville, VA, United States
2
5:15 p.m.
967
DRUG DISCOVERY: TARGETING ATTACHMENT IN GIARDIA
LAMBLIA PATHOGENESIS
Colleen D. Walls, Heidi G. Elmendorf
Georgetown University, Washington, DC, United States
(ACMCIP Abstract)
RELATIONSHIP BETWEEN TREATMENT OUTCOME AND
MOLECULAR MARKERS OF RESISTANCE IN PLASMODIUM FALCIPARUM: A SYSTEMATIC REVIEW AND META-ANALYSIS OF
PUBLISHED DATA
4 p.m.
969
MOLECULAR EVOLUTION OF THE RETURN OF CHLOROQUINESUSCEPTIBLE FALCIPARUM MALARIA IN MALAWI
Miriam K. Laufer1, Fraction K. Dzinjalamala2, Shannon L. Takala1,
Terrie E. Taylor3, Christopher V. Plowe1
1
University of Malawi College of Medicine, Blantyre, Malawi, 3Michigan
State University, East Lansing, MI, United States
2
4:15 p.m.
970
NO GENETIC BOTTLE-NECK IN PLASMODIUM FALCIPARUM
WILD TYPE PFCRT ALLELES RE-EMERGING IN HAINAN ISLAND,
CHINA FOLLOWING HIGH-LEVEL CHLOROQUINE RESISTANCE
Nanhua Chen1, Qi Gao2, Shanqing Wang3, Guangze Wang3,
Michelle Gatton4, Qin Cheng1
1
Australian Army Malaria Institute, Brisbane, Australia, 2Jiangsu Institute of
Parasitic Diseases, Wuxi, China, 3Hainan Provincial Center for Disease
Control and Prevention, Haikou, China, 4Queensland Institute of Medical
Research, Brisbane, Australia
194
4:30 p.m.
www.astmh.org
Symposium 148
971
INDEPENDENT EVOLUTION OF MUTANT DHFR AND
DHPS ALLELES IN AN AREA OF HIGH TRANSMISSION IN
WESTERN KENYA
Andrea M. McCollum1, Sean M. Griffing1, Zhiyong Zhou1, Dianne
J. Terlouw2, Simon Kariuki3, Altaf A. Lal1, Feiko O. ter Kuile2,
Venkatachalam Udhayakumar1, Ananias A. Escalante4
1
Centers for Disease Control and Prevention/CCID/NCZVED/DPD/MB, Atlanta,
GA, United States, 2Liverpool School of Tropical Medicine, Liverpool, United
Kingdom, 3Kenya Medical Research Institute, Kisumu, Kenya, 4Arizona State
University, Tempe, AZ, United States
4:45 p.m.
972
DECLINE IN SULPHADOXINE-PYRIMETHAMINE RESISTANT
DHFR AND DHPS ALLELES AFTER CHANGES IN DRUG POLICY
IN THE AMAZON REGION OF PERU
Zhiyong Zhou1, Sean M. Griffing1, Alexandre Macedo de Oliveira1,
Andrea M. McCollum1, Wilmer Marquino Quezada2, Nancy
Arrospide2, Ananias A. Escalante3, Venkatachalam Udhayakumar1
1
Centers for Disease Control and Prevention, Chamblee, GA, United States,
2
National Institute of Health, Lima, Peru, 3Arizona State University, Tempe,
AZ, United States
The RTS,S Malaria Vaccine: Status and Upcoming
Activities on the Pathway to Registration
Salon F
The RTS,S malaria vaccine has reached Proof of Concept with the demonstration, in a landmark study conducted in Mozambique, of clinical efficacy
in one-to-four-year-old children (Alonso et al., The Lancet 204, 2005). This
milestone triggered an extensive program of Phase 2 studies aimed at confirming and extending the demonstration of efficacy to younger children
and infants, evaluation of a new formulation of the vaccine, evaluation of
various immunization schedules and assessment of immunological compatability with co-administered standard EPI antigens. The program will set the
stage for conducting a large multicenter Phase 3 study in Africa, scheduled
to begin in the first half of 2008. This symposium will summarize the critical
results available from the Phase 2 program, present the design and scientific
rationale for the pivotal Phase 3 study and describe the multiple and interdependent activities necessary to ensure the timely availablity of the vaccine
following the completion of the Phase 3 study.
CHAIR
Barbara Savarese
PATH Malaria Vaccine Initiative, Bethesda, MD, United States
Ripley Ballou
GlaxoSmithKline Biologicals, Rixensart, Belgium
5 p.m.
3:45 p.m.
ASSOCIATION OF MUTATIONS IN PLASMODIUM VIVAX DHFR
AND MDR1 AND IN VIVO RESISTANCE TO AMODIAQUINE
PLUS SULPHADOXINE-PYRIMETHAMINE IN PAPUA NEW
GUINEA
1
2
2
Jutta Marfurt , Frédérique de Monbrison , Sarah Brega , Laetitia
Barbollat2, Ivo Müller3, John C. Reeder3, Hans-Peter Beck1, Stéphane
Picot2, Blaise Genton1
1
Swiss Tropical Institute, Basel, Switzerland, 2Laboratoire de Parasitologie,
Mycologie et Pathologie exotique, Université Claude Bernard, Lyon, France,
3
Papua New Guinea Institute of Medical Research, Goroka, Papua
New Guinea
5:15 p.m.
974
THE CONTRIBUTION OF MÉDECINS SANS FRONTIÈRES TO THE
ASSESSMENT OF EFFICACY OF ANTIMALARIAL TREATMENT,
1996-2004
Jean-Paul Guthmann1, Francesco Checchi1, Ingrid Van den Broek2,
Suna Balkan3, Michel Van Herp4, Eric Comte5, Oscar Bernal6,
Jean-Marie Kindermans4, Elizabeth Ashley1, Dominique Legros1,
Philippe J. Guerin1
1
Epicentre, Paris, France, 2Médecins Sans Frontières, Amsterdam, The
Netherlands, 3Médecins Sans Frontières, Paris, France, 4Médecins Sans
Frontières, Bruxelles, Belgium, 5Médecins Sans Frontières, Geneva,
Switzerland, 6Médecins Sans Frontières, Barcelona, Spain
RECENT CRITICAL RESULTS OBTAINED IN THE ONGOING
PHASE 2 PROGRAM
Eusebio V. Macete
Centro de Investtigacao em Saude de Manhica, Manhica, Mozambique
4:10 p.m.
DESIGN OF PIVOTAL PHASE 3 STUDY AND UNDERLYING SCIENTIFIC RATIONALE
Salim Abdulla
Ifakara Health Research and Development Centre, Bagamoyo, United
4:35 p.m.
PRODUCT DEVELOPMENT ROADMAP: FROM
INVESTIGATIONAL VACCINE TO PRODUCT
REGISTRATION AND IMPLEMENTATION
Alan Brooks
PATH Malaria Vaccine Initiative, Bethesda, MD, United States
5 p.m.
PRODUCT DEVELOPMENT ROADMAP: FROM
INVESTIGATIONAL VACCINE TO PRODUCT
REGISTRATION AND IMPLEMENTATION
Joe Cohen
GlaxoSmithKline Biologicals, Rixensart, Belgium
195
973
Detailed Program
www.astmh.org
4:45 p.m.
979
Mosquitoes - Biochemistry, Molecular Biology and
Molecular Genetics II
Salon IJ
INVESTIGATIONS OF QUANTITATIVE GENE
EXPRESSION ANALYSIS AS A METHOD FOR
PREDICTING THE AGES OF MOSQUITOES
3:45 p.m. - 5:30 PM
Leon E. Hugo1, Peter E. Cook2, Scott L. O’Neill2, Brian H. Kay1,
Peter A. Ryan1
CHAIR
1
Queensland Institute of Medical Research, Brisbane, Australia, 2School of
Integrative Biology, University of Queensland, Brisbane, Australia
Leon E. Hugo
5 p.m.
Roger Miesfeld
980
A DENSONUCLEOSIS VIRUS FROM ANOPHELES GAMBIAE
3:45 p.m.
Xiaoxia Ren, Jason Rasgon
975
TRANSCRIPTIONAL REGULATION OF PROTEASE GENE
EXPRESSION IN THE MIDGUT OF AEDES AEGYPTI MOSQUITOES
Roger L. Miesfeld, Susan Kunz, Jun Isoe, James E. Pennington,
James Morton
United States
(ACMCIP Abstract)
5:15 p.m.
981
TOWARDS A VACCINE AGAINST CANINE VISCERAL LEISHMANIASIS BASED ON VECTOR SALIVARY ANTIGENS
4 p.m.
976
Nicolas Collin, Shaden Kamhawi, Regis B. Gomes, Clarissa Teixeira,
Dia-eldin Elnaiem, Jesus G. Valenzuela
FUNCTIONAL CHARACTERIZATION OF LIPID SYNTHESIS,
TRANSPORT, AND STORAGE IN AEDES AEGYPTI MOSQUITOES
Jorge Zamora, Kelsey Thorson, James E. Pennington, Jun Isoe,
Rolf Ziegler, Roger L. Miesfeld
(ACMCIP Abstract)
4:15 p.m.
977
Intestinal and Tissue Helminths III: Nematodes
Salon KL
HEMOZOIN-ACTIVATED INNATE IMMUNE RESPONSES IN
ANOPHELES MOSQUITOES
3:45 p.m. - 5:30 PM
Leyla Akman-Anderson1, Martin Olivier2, Shirley Luckhart1
CHAIR
1
University of California Davis, Davis, CA, United States, 2McGill University,
Montreal, QC, Canada
James B. Lok
4:30 p.m.
Martin Montes
978
THE REGULATION OF ANOPHELES GAMBIAE
FEEDING BEHAVIOR BY ITS CIRCADIAN CLOCK
Instituto de Medicina Tropical ‘Alexander von Humboldt, Lima, Peru
3:45 p.m.
982
Suchismita Das, George Dimopoulos
States
NEW MECHANISMS IN THE EXPULSION OF GUT NEMATODES:
A IMMUNOCYTOCHEMICAL AND MICRO-ARRAY ANALYSIS
Charles Mackenzie1, John Stout2, Anna Langerveld2, Charles Ide2,
Rob Eversole2
1
Michigan State University, Dimondale, MI, United States, 2Western
Michigan University, Kalamazoo, MI, United States
196
4 p.m.
www.astmh.org
5 p.m.
983
987
SELENIUM (SE) DEFICIENCY DIMINISHES DIAPHORASE
ACTIVITY ASSOCIATED WITH ALTERNATIVELY ACTIVATED
MACROPHAGES AND BLOCKS RESISTANCE TO
HELIGMOSOMOIDES POLYGYRUS
EXPRESSION, REFOLDING AND NEUTRALISATION OF CONFORMATIONALLY ACTIVE FORMS OF THE HOOKWORM VACCINE
ANTIGEN, NA-APR-1
Joseph Urban1, Alan Smith1, Sebastian Botero1, Harry Dawson1,
Robert Anthony2, William Gause3, Terez Shea-Donohue4
1
U.S. Department of Agriculture, Beltsville, MD, United States, 2The
Rockefeller University, New York, NY, United States, 3University Medical and
Dental School of New Jersey, Newark, NJ, United States, 4University of
Maryland School of Medicine, Baltimore, MD, United States
Mark S. Pearson1, Darren Pickering1, Peter Hotez2, Alex Loukas1
Queensland Institute of Medical Research, Herston, Queensland, Australia,
George Washington University, Washington, DC, United States
2
1
(ACMCIP Abstract)
5:15 p.m.
988
(ACMCIP Abstract)
4:15 p.m.
984
EXPRESSION AND INTRA-CELLULAR LOCALIZATION OF FKTF-1
IN TRANSGENIC STRONGYLOIDES STERCORALIS
Michelle L. Castelletto, Holman C. Massey, James B. Lok
(ACMCIP Abstract)
IMPACT OF MASS DRUG ADMINISTRATION ON THE
DEVELOPMENT OF POSSIBLE BENZIMIDAZOLE RESISTANCE OF
HUMAN HOOKWORMS IN HAITI
Jan M. Schwenkenbecher1, Patrick J. Lammie2, Ray M. Kaplan1
1
University of Georgia, Athens, GA, United States, 2Centers for Disease
Control and Prevention, Atlanta, GA, United States
Symposium 151
Leishmaniasis: Post-Genome Era
985
IDENTIFICATION OF DIFFERENCES IN PROTEIN SECRETION
FROM INFECTIVE LARVAE AND FREE-LIVING STAGES OF
STRONGYLOIDES RATTI WITH PUTATIVE RELEVANCE FOR THE
FORM OF LIFE
Hanns Soblik1, Hanno Steen2, Makedonka Mitreva3, Nadine
Borchert1, Peter U. Fischer4, Yasmina Tazir1, Norbert W. Brattig1
1
Proteomics Center, Children’s Hospital Boston, Boston, MA, United States,
3
Genome Sequencing Center, Washington University, St. Louis, MO, United
States, 4Department of Internal Medicine, Washington University, St. Louis,
MO, United States
2
Liberty AB
This symposium is designed to discuss how researchers can take full use of
Leishmania (L. major, L. infantum and L. braziliensis) and mammals (human
and mouse) genome data. Four major aspects will be included. First, genetic
explanation for why the three Leishmania spp. cause different clinical manifestations, i.e., cutaneous, visceral and mucocutanous leishmaniases; second, differential profile of gene expression in the developmental stages of
Leishmania spp; third, changes in mammalian hosts induced by Leishmania
spp. infection; and finally, mechanisms of drug resistance in leishmaniasis
treatment.
CHAIR
Chaoqun Yao
4:45 p.m.
University of Iowa, and VA Medical Center, Iowa City, IA, United States
986
CD4+CD25+FOXP3+ T-REGULATORY CELLS ARE EXPANDED IN
HTLV-1 PATIENTS WITH STRONGYLOIDIASIS
Martin Montes1, Cesar Sanchez1, Eduardo Gotuzzo1,
A. Clinton White2
1
Instituto de Medicina Tropical ‘Alexander von Humboldt’ Universidad
Peruana Cayetano Heredia, Lima, Peru, 2University of Texas Medical Branch
in Galveston, Galveston, TX, United States
(ACMCIP Abstract)
3:45 p.m.
FIRST STEPS TOWARDS ELUCIDATING PROTEINPROTEIN INTERACTION NETWORKS IN TRYPANOSOMATID
PARASITIC PROTOZOA
Gustavo Cerqueira
University of Maryland, College Park, MD, United States
4:10 p.m.
PROTEIN AND RNA CHANGES DURING LEISHMANIA DONOVANI PROMASTIGOTE-TO-AMASTIGOTE DIFFERENTIATION
Peter Myler
Seattle Biomedical Research Institute and University of Washington, Seattle,
WA, United States
197
4:30 p.m.
www.astmh.org
Detailed Program
4:35 p.m.
5 p.m.
MICROARRAY ANALYSES OF MACROPHAGE GENE EXPRESSION DURING PHAGOCYTOSIS OF LEISHMANIA CHAGASI
Mary E. Wilson
TALES FROM THE ENDGAME: RESEARCH PRIORITIES
FOR MANAGING LATE STAGES OF FILARIASIS
ELIMINATION PROGRAMS
University of Iowa, and VA Medical Center, Iowa City, IA, United States
Patrick J. Lammie
5 p.m.
MECHANISMS OF DRUG RESISTANCE IN
TREATING LEISHMANIASIS
Symposium 153
Marc Ouellette
Factors Associated on Emergence and Reemerging
of Arboviruses
Laval University, Quebec City, QC, Canada
Symposium 152
Filariasis Elimination: Knowing When to Say “When”
Liberty C
The Global Programme to Eliminate Lymphatic Filariasis (GPELF) is largely
based on a strategy of mass drug administration (MDA) with antifilarial
medications to reduce infection rates and levels in humans below those
required for sustained transmission by mosquitoes. Initiated in several countries in 2000, GPELF rapidly expanded to reach more than 380 million people in 2005. This is easily the largest global health intervention initiated to
date based on mass drug administration. A number of countries have completed 5 or more rounds of MDA, and GPELF is now facing difficult decisions on targets and endpoints for MDA programs. This symposium will
address these timely questions from several different perspectives.
Franklin 1
This symposium will update several aspects on emergence and/or reemergence of certain arboviruses. The speakers will discuss the recent findings
on epidemiology, clinical and laboratory of Chikungunya fever, Mayaro
fever, Oropouche fever and Rift Valley fever viruses, as well as the factors
associated with their emergence/re-emergence and recent widespread to
new areas.
CHAIR
Pedro F. Vasconcelos
Robert B. Tesh
3:45 p.m.
CHAIR
CHIKUNGUNYA FEVER
Gary J. Weil
Ann Powers
Reda M. Ramzy
Ain Shams University, Cairo, Egypt
4:10 p.m.
MAYARO FEVER
3:45 p.m.
Robert B. Tesh
MEASURING THE GLOBAL PROGRAMME TO ELIMINATE
LYMPHATIC FILARIASIS: FROM MAPPING TO MONITORING
TO ENDPOINTS
Eric A. Ottesen
OROPOUCHE FEVER
Taskforce for Child Survival, Decatur, GA, United States
Márcio R. Nunes
4:35 p.m.
4:10 p.m.
THE IMPACT OF MASS DRUG ADMINISTRATION ON FILARIASIS PREVALENCE AND TRANSMISSION PARAMETERS WITH
PROPOSED ENDPOINTS
5 p.m.
Gary J. Weil
RIFT VALLEY FEVER
Tom G. Ksiazek
4:35 p.m.
WHEN CAN MASS DRUG ADMINISTRATION FOR LYMPHATIC
FILARIASIS BE STOPPED? A MODELING PERSPECTIVE
Wilma A. Stolk
Erasmus MC, Rotterdam, The Netherlands
198
Symposium 154
Integrated Vector Management in Africa Contributions of Molecular Entomology, Biochemistry
and Social Science to Malaria Control
Viruses II
www.astmh.org
Franklin 3/4
Franklin 2
3:45 p.m. - 5:30 PM
CHAIR
CHAIR
Olumide Ogundahunsi
Hilary Ranson
Imperial College, London, United Kingdom
3:45 p.m.
SOCIO-CULTURAL PRACTICES AND LONGEVITY/DURATION OF
EFFICACY OF INSECTICIDE TREATED BED NETS IN BENIN,
BURKINA FASO AND IVORY COAST
Julien M. Doannio
Kenneth J. Linthicum
U.S. Department of Agriculture, Gainesville, FL, United States
Kate Rubins
Whitehead Institute, Cambridge, MA, United States
3:45 p.m.
989
FORECASTING THE TEMPORAL AND SPATIAL DISTRIBUTION
OF A RIFT VALLEY FEVER OUTBREAK IN EAST AFRICA: 20062007
Assaf Anyamba1, Jean-Paul Chretien2, Jennifer Small1,
Compton J. Tucker1, Pierre Formenty3, Jason Richardson4,
Seth Britch5, Kenneth J. Linthicum5
1
Goddard Space Flight Center, Biospheric Sciences Branch, Greenbelt, MD,
United States, 2Department of Defense Global Emerging Infections
Surveillance and Response System, Division of Preventive Medicine, Walter
Reed Army Institute of Research, Silver Spring, MD, United States, 3Bio-risk
Reduction for Dangerous Pathogens, Department of Epidemic and Pandemic
Alert and Response, World Health Organization, Geneva, Switzerland,
4
Department of Entomology and Vector-borne Disease, U.S. Army Medical
Research Unit - Kenya, Nairobi, Kenya, 5USDA-ARS Center for Medical,
Agricultural and Veterinary Entomology, Gainesville, FL, United States
4 p.m.
990
National Institute for Public Health, Abidjan, Cote d’Ivoire
4:15 p.m.
STATUS OF INSECTICIDE RESISTANCE IN KENYA
Luna Kamau
Kenya Medical Research Institute, Nairobi, Kenya
4:35 p.m.
INSECTICIDE SUSCEPTIBILITY DATA IN THE RATIONAL USE OF
DDT FOR MALARIA VECTOR CONTROL IN NIGERIA
Taiwo Samson Awolola
Nigerian Institute for Medical Research, Lagos, Nigeria
5 p.m.
THE ECOLOGICAL GENETICS OF THE WEST AFRICAN
ANOPHELES FUNESTUS
Sagnon N’Fale
CNRFP, Ouagadougou, Burkina Faso
EXAMINATION OF RIFT VALLEY FEVER VIRUS ENTRY
DETERMINANTS USING SIRNA
Claire Marie Filone, Robert W. Doms, Sara Cherry
4:15 p.m.
991
CHARACTERIZATION OF A NOVEL BRAZILIAN VACCINIA VIRUS
ISOLATED FROM HUMAN AND COMPARATIVE ANALYSIS
WITH ORTHOPOXVIRUSES
Giliane Trindade1, Ginny Emerson1, Scott Sammons2, Mike Frace2,
Dhwani Govil2, Melissa Olsen-Rasmussen2, Yu Li1, Darin Carroll1,
Russell Regnery1, Flavio Guimaraes da Fonseca3, Erna Kroon3,
Inger Damon1
1
CCID/DVRD/PRB/Centers for Disease Control and Prevention, Atlanta, GA,
United States, 2CCID, Centers for Disease Control and Prevention, Atlanta,
GA, United States, 3Federal University of Minas Gerais State, Belo Horizonte,
Minas Gerais, Brazil
(ACMCIP Abstract)
199
This symposium is designed to highlight the value of multiple disciplines in
the application of integrated vector management for preventing malaria in
Africa. The Special Programme for Research and Training in Tropical Diseases
(WHO/TDR) and the Multilateral Initiative on Malaria (MIM) support several
research programmes on malaria vectors. In Africa, there is increasing use of
insecticide-treated bed nets, application of indoor residual spraying and an
imminent re-introduction of dichlorodiphenyltrichloroethane (DDT) for vector
control. The importance of Anopheles funestus in malaria transmission across
Africa is also receiving increasing recognition. Results from research across
several disciplines being conducted by groups across Africa will be presented.
The results are highly relevant for integrated vector management in the
Africa and in some cases, already informing the vector management strategy.
The implications for malaria transmission and prevention will be discussed.
Detailed Program
www.astmh.org
4:30 p.m.
992
PATHOGENESIS OF MONKEYPOX IN CYNOMOLGUS
MACAQUES: DEVELOPMENT OF A NON-HUMAN PRIMATE
MODEL FOR THERAPEUTIC AND VACCINE TESTING
Kate Rubins1, Jay Goff2, Eric Mucker2, Chris Hartmann2,
David Miller2, JoLynne Raymond2, John Huggins2, Lisa Hensley2
1
Plenary Session IV: Presidential Address and
Salon GH
Wednesday, November 7, 2007 6 p.m. - 7:30 p.m.
ASTMH presidential address and annual business meeting.
CHAIR
Whitehead Institute, Cambridge, MA, United States, 2US Army Medical
Research Institute of Infectious Diseases, Frederick, MD, United States
George Hillyer
4:45 p.m.
Edward T. Ryan
993
EVALUATION OF CATIONIC LIPID DNA COMPLEX (CLDC)
IN SMALL ANIMAL MODELS AS A PLATFORM FOR BOTH
THERAPEUTIC TREATMENT AND VACCINE DEVELOPMENT
FOR ALPHAVIRUS INFECTIONS
Christopher H. Logue1, Chris Bosio2, Steven Dow3,
Kenneth E. Olson2, Ann M. Powers1
1
6 p.m.
INTRODUCTION
Richard W. Steketee
PATH Malaria Control and Evaluation Partnership in Africa, Seattle, WA,
United States
Centers for Disease Control and Prevention, Fort Collins, CO, United States,
AIDL - Colorado State University, Fort Collins, CO, United States, 3IDA Colorado State University, Fort Collins, CO, United States
6:15 p.m.
5 p.m.
2
994
GENETIC CHARACTERIZATION OF HIGHLY PATHOGENIC H5N1
AVIAN INFLUENZA A VIRUSES ISOLATED FROM
SOUTHWESTERN NIGERIA
Comfort O. Aiki-Raji1, Patricia V. Aguilar2, David Swayne3,
Yong-Kuk Kwon3, Sue Goetz3, David L. Suarez3, Oyekanmi Nash4,
Christopher A. Adeyefa5, Festus D. Adu1, Christopher F. Basler2
AFRICA TELLS US THE STORY: WHAT SUCCESS IN
MALARIA CONTROL MEANS, NOW AND IN THE FUTURE
6:45 p.m.
ASTMH ANNUAL BUSINESS MEETING
George Hillyer
1
Department of Virology, University of Ibadan, Oyo State, Nigeria,
Department of Microbiology, Mount Sinai School of Medicine, New York,
NY, United States, 3Southeast Poultry Research Laboratory, Agricultural
Research Service, U.S. Department of Agriculture, Athens, GA, United
States, 4Institute for Advanced Medical Research and Training, College of
Medicine, University of Ibadan, Oyo State, Nigeria, 5Department of
Veterinary Medicine, University of Ibadan, Oyo State, Nigeria
2
Poster Session C Dismantle
Franklin Hall B
7 p.m. - 8 p.m.
5:15 p.m.
995
GLOBAL TRENDS IN EMERGING INFECTIOUS DISEASES
Peter Daszak1, Kate Jones2, Marc Levy3, John Gittleman4,
Nikki Patel1, Valentina Mara3, Sara F. Nakielny5, Joanne Chan5,
Maria N. Labo5
1
Consortium for Conservation Medicine, New York, NY, United States,
Institute of Zoology, London, United Kingdom, 3Center for International
Earth Science Information Network, Palisades, NY, United States, 4University
of Georgia, Athens, GA, United States, 5Johns Hopkins Bloomberg School of
2
200
www.astmh.org
8:15 a.m.
997
Registration
Thursday, November 8, 2007 7 a.m. - 10:30 a.m.
Cyber Cafe
Franklin Hall Foyer
ACUTE CHAGAS DISEASE (ACD) OUTBREAK RELATED TO
SUGAR CANE JUICE DRUNK IN SANTA CATARINA STATE,
SOUTH BRASIL
Erica Tatto1, José A. Menezes1, Beatriz Y. Kitagawa1, Daniel
Freitas1, George S. Dimech1, Marcelo Y. Wada1, Marcos T. Obara1,
Andreza Madeira2, Suzana Zeccer2, Fernanda Laupert3, Marli
Aguiar3, Mario Steindel4, Douglas Hatch5
1
Speaker Ready Room
Ministry of Health - Brasil, Brasilia, Brazil, 2State Secretariat of Health,
Santa Catarina, Brazil, 3Central Laboratory of Public Health, Santa Catarina
State, Brazil, 4Federal University of Santa Catarina State, Santa Catarina
State, Brazil, 5Centers for Disease Control and Prevention, Atlanta, GA,
United States
Rooms 413-415
Thursday, November 8, 2007 7 a.m. - Noon
8:30 a.m.
998
EPIDEMIOLOGY OF TRYPANOSOMA CRUZI FROM THE
SOUTHEASTERN UNITED STATES
Rooms 303-304
Thursday, November 8, 2007 7:30 a.m. - 9:30 a.m.
Michael J. Yabsley, Dawn M. Roellig, Emily M. Brown,
Wendy Fujita, Mason Y. Savage
Press Room
Room 404
(ACMCIP Abstract)
Thursday, November 8, 2007 8 a.m. - 2 p.m.
8:45 a.m.
999
Kinetoplastida II: Epidemiology, Diagnosis and
Treatment
THE ROLE OF SOCIAL EXCLUSION AND DEFORESTATION IN
THE SPATIO-TEMPORAL PATTERNS OF CUTANEOUS
LEISHMANIASIS IN COSTA RICA
Salon AB
Luis F. Chaves, Justin M. Cohen, Mercedes Pascual, Mark L. Wilson
University of Michigan, Ann Arbor, MI, United States
Thursday, November 8, 2007
8 a.m. - 9:45 a.m.
9 a.m.
1000
CHAIR
Mark L. Wilson
CLIMATE VARIABILITY AND LEISHMANIASIS IN COLOMBIA
University of Michigan School of Public Health, Ann Arbor, MI, United States
Michael J. Yabsley
1
Instituto Departamental de Salud de Norte de Santander, Cucuta,
Colombia, 2Grupo de Investigación en Enfermedades Parasitarias, Tropicales
e Infecciosas, Instituto de Investigación en Ciencias Biomédicas, Universidad
de Pamplona, Pamplona, Colombia, 3Universidad de Los Andes, Trujillo,
Venezuela, 4Emory University, Atlanta, GA, United States
8 a.m.
996
COMPARISON OF BLOOD DONOR CHAGAS RISK
ACROSS 3 CALIFORNIA SITES
2
Leslie S. Wilson , Janine Ramsey , Christi Motter , Leslie H.
Tobler3, Leopoldo Valiente-Banuet4, Rene T. Leyva2, Yelena B.
Koplowicz1, Sagrario Romero-Estrella4
1
University of California at San Francisco, San Francisco, CA, United States,
National Institute for Public Health, Cuernavaca, Mexico, 3Blood Systems
Research Institute, San Francisco, CA, United States, 4National Center for
Blood Transfusion, Mexico City, Mexico
2
9:15 a.m.
1001
1
EFFICACY OF MILTEFOSINE FOR BOLIVIAN
CUTANEOUS LEISHMANIASIS
Jaime Soto1, J. Rea2, M. Balderrama2, J. Toledo1, J. Soto1, L. Valda3,
Josh Berman4
1
Fundación FADER, Bogota, Colombia, 2Puesto de Salud, Campamento
OSCAR, Palos Blancos, Colombia, 3Hospital de Clínicas, La Paz, Bolivia,
4
Private Practice, North Bethesda, MD, United States
201
1
Rocio Cardenas1, Claudia Sandoval2, Alfonso J. RodriguezMorales3, Carlos Franco-Paredes4
Detailed Program
www.astmh.org
9:30 a.m.
1002
PARASITE TUBULIN AS A DRUG TARGET
Karl Werbovetz1, Molla Endeshaw1, Rachel Morgan1, Chenglong
Li1, Karthikeyan Diraviyam2, David Sept2
1
The Ohio State University, Columbus, OH, United States, 2Washington
University, St. Louis, MO, United States
Clinical Tropical Medicine III
Salon E
8 a.m. - 9:45 a.m.
CHAIR
Christina A. Greenaway
Symposium 158
Roles of CD8 T Cells in the Control of Parasitic
Infections
Salon CD
SMBD Jewish General Hospital, Montreal, QC, Canada
Parsotam R. Hira
Kuwait University, Kuwai City, Kuwait
8 a.m.
1003
This symposium is designed to review and update progress in the effort to
understand the underlying mechanisms by which CD8 T cells contribute to
the control of parasitic diseases, and also new approaches for the targeting
of CD8 T cells in vaccine development. This topic should be of general interest to ASTMH members who are concerned with vaccine development and
pathogenesis (viral, bacterial, as well as parasitic).
THE EFFECT OF COMPLIANCE UPON CLINICAL EFFECTIVENESS
OF CHLORPROGUANIL-DAPSONE (CD) AND ARTEMETHERLUMEFANTRINE (AL) WHEN COMPARED TO SULFADOXINEPYRIMETHAMINE (SP) FOR THE TREATMENT OF UNCOMPLICATED FALCIPARUM MALARIA IN MALAWI - A RANDOMISED
CONTROLLED TRIAL
CHAIR
David J. Bell1, Dan Wootton1, Mavuto Mukaka2, Jacqui
Montgomery2, Noel Kayange3, Phillips Chimpeni2, Edward Zijlstra3,
Dyfrig A. Hughes1, Malcolm E. Molyneux2, Steve A. Ward4, Peter A.
Winstanley1, David G. Lalloo4
Diane McMahon-Pratt
Fidel Zavala
8 a.m.
GENERATION OF EFFECTOR CD8 T CELL IMMUNITY AGAINST
ORAL T. GONDII INFECTION
1
University of Liverpool, Liverpool, United Kingdom, 2Malawi-LiverpoolWellcome Trust Clinical Research Programme, Blantyre, Malawi, 3College of
Medicine, Blantyre, Malawi, 4Liverpool School of Tropical Medicine,
Liverpool, United Kingdom
8:15 a.m.
1004
Imitiaz Khan
George Washington University Medical Center, Washington, DC,
United States
8:25 a.m.
GENERATION OF IMMUNODOMINANT CD8+ T CELL
POPULATIONS DURING TRYPANOSOMA CRUZI INFECTION
Diana Martin
8:50 a.m.
ARE LEISHMANIA PARASITES LIMITING THE DEVELOPMENT
OF PROTECTIVE T-CELL RESPONSES?
Simona Stager
RESULTS OF A RANDOMISED, MULTICENTRE, PHASE II, DOSERANGING CLINICAL STUDY TO ASSESS THE SAFETY AND EFFICACY OF FIXED DOSE, ORALLY ADMINISTERED PYRONARIDINE AND ARTESUNATE IN ADULT PATIENTS WITH ACUTE
UNCOMPLICATED PLASMODIUM FALCIPARUM MALARIA
Presented by Srivicha Krudsood, Mahidol University, Bangkok,
Thailand
Sornchai Looareesuwan1, Oumar Gaye2, Emiliana Tjitra3, Kalifa
Bojang4, Duong Socheat5, Patrice Piola6
1
Bangkok Hospital for Tropical Diseases, Faculty of Tropical Medicine,
Mahidol University, Bangkok, Thailand, 2Department of Parasitology, Faculty
of Medicine, University Cheikh Anta Diop, Dakar, Senegal, 3Bethesda
Hospital, Tomohon, North-Sulawesi, Indonesia, Indonesia, 4Medical Research
Council, Fajara, Banjul, Gambia, 5National Malaria Center, Phnom Penh,
Cambodia, 6MSF Epicentre, Mbarara, Uganda
9:15 a.m.
PROTECTIVE AND PATHOGENIC ROLES OF CD8+ T CELLS
DURING MALARIA INFECTION
Fidel Zavala
Johns Hopkins University, Bloomberg School of Public Health, Baltimore,
MD, United States
202
8:30 a.m.
www.astmh.org
9:30 a.m.
1005
EFFICACY OF ARTESUNATE-AMODIAQUINE (ASAQ) FOR THE
TREATMENT OF UNCOMPLICATED FALCIPARUM MALARIA IN
SUB-SAHARAN AFRICA: AN INDIVIDUAL PATIENT DATA META
ANALYSIS (IPDM) IN 3,455 PATIENTS
Julien Zwang1, Piero Luigi Olliaro2, François Nosten1, H Barennes3,
P. Brasseur3, G. Dorsey3, J.P. Guthmann3, A Martensson3, U
D’Alessandr3o, M Vaillant3
1
Shoklo Malaria Research Unit, Mahidol University, Mae Sot, Thailand,
TDR/WHO, Geneva, Switzerland, 3ASAQ, Study Group, Switzerland
1009
LICENSED CGMP INTRAVENOUS ARTESUNATE AVAILABILITY
IN THE DEVELOPED WORLD: LIGHT FINALLY AT THE END OF
THE TUNNEL
Peter J. Weina1, R. Scott Miller1, Rudolf Kuppers2, Gianfranco
Fornasini3, Wilbur K. Milhous1
1
Military Infectious Diseases Research Program, Fort Detrick, MD, United
States, 3Sigma-Tau Pharmaceuticals Inc., Gaithersburg, MD, United States
2
2
Symposium 160
8:45 a.m.
1006
QTC INTERVAL CHANGES FOLLOWING MEFLOQUINE AND
ARTESUNATE COMBINATIONS IN MALARIA PATIENTS AND
NORMAL VOLUNTEERS.
Walter Taylor1, Srivicha Krudsood2, Noppadom Tangpukdee2, P.
Wilairatama2, Sornchai Looareesuwan2, U. Silachamroon2, Suresh
Ramanathan3, V. Navaratnam3, Michel Vaillant4, JR Kiechel5
1
Oxford University, Hanoi, Vietnam, 2Mahidol University, Bangkok, Thailand,
Universiti Sains Malaysia, Penang, Malaysia, 4Centre for Health Studies,
CRP-SANTE, Luxembourg, Luxembourg, 5Drugs for Neglected Diseases,
Geneva, Switzerland
3
9 a.m.
Japanese Encephalitis Update and Progress on
Surveillance and Disease Control in Endemic Settings
Salon F
The symposium will update on recent progress in JE surveillance, diagnostic
development, disability assessment and vaccine introduction and impact.
New data will be shared from integrated meningo-encephalitis surveillance
in JE endemic countries, Cambodia and China. We will also discuss new
tools to estimate and quantify disability in JE-affected patients. Finally, we
will review new data on immunization impact from the introduction of JE
vaccine and post-marketing surveillance in India and Nepal.
CHAIR
1007
PHARMACOKINETICS AND EFFICACY OF PIPERAQUINE AND
CHLOROQUINE IN MELANESIAN CHILDREN WITH UNCOMPLICATED MALARIA
Harin A. Karunajeewa1, Kenneth F. Ilett1, Ivo Mueller2, Peter
Siba2, Madhu Page-Sharp1, Enmoore Lin2, Jovitha Lammey2, Kevin T.
Batty3, Timothy M. Davis1
1
School of Medicine and Pharmacology, University of Western Australia,
Perth, Australia, 2Papua New Guinea Institute of Medical Research, Goroka,
Papua New Guinea, 3School of Pharmacy, Curtin University, Perth, Australia
Marc Fischer
Susan Hills
8 a.m.
JE DISABILITY ASSESSMENT IN ENDEMIC COUNTRIES AND
VALIDATION OF A SIMPLIFIED TOOL
Tom Solomon
1008
DOXYCYCLINE HYCLATE TOLERABILITY AND COMPLIANCE AS
DAILY ORAL MALARIA PROPHYLAXIS IN FIELD CONDITIONS:
EXPERIENCE OF THE 10TH MOUNTAIN DIVISION (LI), OEF VII
David Saunders1, Eric Garges1, Andrew Kosmowski2, Kent
Bennett1, Steven Cersovsky1, Robert Mott1, Alan Magill1
1
Fort Drum, Fort Drum, NY, United States
2
8:30 a.m.
JE DIAGNOSTICS FOR SUPPORT OF SURVEILLANCE IN DEVELOPING COUNTRIES
Barbara W. Johnson
8:55 a.m.
JE SURVEILLANCE THROUGH INTEGRATED MENINGOENCEPHALITIS SURVEILLANCE
Susan Hills
9:20 a.m.
JE VACCINES: AN UPDATE AND RECENT DEVELOPMENTS
Mansour Yaich
203
9:15 a.m.
Detailed Program
www.astmh.org
8:45 a.m.
1011
American Committee of Molecular, Cellular
and Immunoparasitology (ACMCIP):
Molecular Parasitology I
EVIDENCE OF GENE-SPECIFIC TRANSCRIPTIONAL SILENCING
BY RNAI IN STRONGYLOIDES STERCORALIS
Salon G
8 a.m. - 9:45 a.m.
CHAIR
Xinshe Li, James B. Lok
9 a.m.
1012
DEVELOPMENT OF TRANSGENIC PLASMODIUM BERGHEI
EXPRESSING P. FALCIPARUM SEXUAL ANTIGEN PFS25 FOR IN
VIVO ASSESSMENT OF TRANSMISSION BLOCKING IMMUNITY
Steven Williams
Godfree Mlambo, Jorge Maciel, Nirbhay Kumar
Smith College/University of Massachusetts, Northampton, MA, United States
United States
Nirbhay Kumar
8 a.m.
1073
CHARACTERIZATION OF THE APIAP2 DNA-BINDING PROTEINS
IN PLASMODIUM FALCIPARUM
Erandi DeSilva1, Jasdave Chahal1, Ilsa Leon1, Andrew Gehrke2,
Martha Bulyk2, Manuel Llinas1
1
Princeton University, Princeton, NJ, United States, 2Brigham and Women's
Hospital and Harvard Medical School, Boston, MA, United States
8:15 a.m.
1074
POLYADENYLATION STABILIZES TRANSLATIONALLY-COMPETENT MRNAS IN TRYPANOSOME MITOCHONDRIA
Ronald Etheridge, Inna Aphasizheva, Ruslan Aphasizhev
Department of Microbiology and Molecular Genetics, University of California
at Irvine, Irvine, CA, United States
8:30 a.m.
1010
PIGGYBAC TRANSPOSON MEDIATED TRANSGENESIS OF THE
HUMAN BLOOD FLUKE, SCHISTOSOMA MANSONI
Maria E. Morales1, Victoria H. Mann2, Kristine J. Kines1, Geoffrey
Gobert3, Malcolm J. Fraser4, Bernd H. Kalinna5, Jason M. Correnti6,
Edward J. Pearce6, Paul J. Brindley1
1
Department of Tropical Medicine, and Biomedical Sciences Program,
2
Department of Tropical Medicine, Tulane University Health Sciences
Center, New Orleans, LA, United States, 3Division of Infectious Diseases
and Immunology, Queensland Institute of Medical Research, Brisbane,
Queensland, Australia, 4Department of Biological Sciences, University
of Notre Dame, South Bend, IN, United States, 5Centre for Animal
Biotechnology, Faculty of Veterinary Science, The University of
Melbourne, Parkville, Victoria, Australia, 6Department of Pathobiology,
School of Veterinary Medicine, University of Philadelphia, Philadelphia,
PA, United States
9:15 a.m.
1013
STAGE-SPECIFIC REGULATION OF TRANSCRIPTIONAL ACTIVITY
IN PLASMODIUM FALCIPARUM DURING THE INTRAERYTHROCYTIC DEVELOPMENTAL CYCLE
Jennifer S. Sims1, Kevin T. Militello2, Peter A. Sims3, Vishal P.
Patel1, Jacob M. Kasper1, Dyann F. Wirth1
1
Harvard School of Public Health, Boston, MA, United States, 2State
University of New York - Geneseo, Geneseo, NY, United States, 3Harvard
University, Cambridge, MA, United States
9:30 a.m.
1014
STAGE-SPECIFIC DETECTION OF BRUGIA MALAYI INFECTIVE
LARVAE IN MOSQUITOES
Sandra J. Laney1, Caitlin Buttaro1, Sabato Visconti1, Gary J. Weil2,
Reda Ramzy3, Steven A. Williams1
1
Smith College, Northampton, MA, United States, 2Washington University
School of Medicine, St. Louis, MO, United States, 3Ain Shams University,
Cairo, Egypt
Malaria - Biology and Pathogenesis I
Salon H
8 a.m. - 9:45 a.m.
CHAIR
Ambroise D. Ahouidi
Le Dantec Hospital and Cheikh Anta Diop, Dakar, Senegal
Miranda Oakley
204
8 a.m.
www.astmh.org
9:15 a.m.
1015
1020
SELECTION OF MUTATED PLASMODIUM FALCIPARUM
MALARIA PARASITES FOR LONG-LIVED INVASIVE
MEROZOITES BY LIMITING THEIR CONTACT WITH
ERYTHROCYTES (RBC) USING LOW RBC CONCENTRATIONS IN
CONTINUOUS MOTION SUSPENSION CULTURES
REGULATION OF PLASMODIUM FALCIPARUM
GLYCOSYLPHOSPHATIDYLINOSITOL-INDUCED CYTOKINE
RESPONSES BY MAPK-ACTIVATED PROTEIN KINASE 2
AND P38 MAPK
J. David Haynes, J. Kathleen Moch, Jack L. Komisar,
Jeffrey D. Snavely
Pennsylvania State University College of Medicine, Hershey, PA, United
States
(ACMCIP Abstract)
Jianzhong Zhu, Gowdahalli Krishnegowda, D. Channe Gowda
(ACMCIP Abstract)
9:30 a.m.
8:15 a.m.
1021
1016
APOPTOSIS STALKS AN EXPONENTIALLY GROWING
PLASMODIUM FALCIPARUM CULTURE
Beth K. Mutai, John N. Waitumbi
Walter Reed Project/Kenya Medical Research Institute, Kisumu, Kenya
(ACMCIP Abstract)
MOLECULAR AND IMMUNOLOGICAL ANALYSES OF A MAJOR
SEQUENCE POLYMORPHISM IN THE PLASMODIUM FALCIPARUM INVASION LIGAND PFRH2B
Ambroise D. Ahouidi1, Amy K. Bei2, Cameron V. Jennings2,
Ousmane Sarr1, Omar Ndir1, Dan A. Milner2, Sarah K. Volkman2,
Terrie E. Taylor3, Zul Premji4, Dyann F. Wirth2, Souleymane Mboup1,
Manoj T. Duraisingh2
1
8:30 a.m.
Le Dantec Hospital and Cheikh Anta Diop University, Dakar, Senegal,
Harvard School of Public Health, Boston, MA, United States, 3University of
Malawi College of Medicine, Blantyre, Malawi, 4Muhimbili University College
of Health Sciences, Dar es Salaam, United Republic of Tanzania
2
1017
MOLECULAR MARKERS OF THE PATHOGENESIS OF CEREBRAL
MALARIA IN THE MURINE MALARIA PLASMODIUM BERGHEI
1
1
(ACMCIP Abstract)
2
Miranda Oakley , Laurence Faucette , Victoria Majam , Hong
Zheng2, Babita Mahajan2, Cindy Erexson1, Jerrold Ward1, Thomas
McCutchan1, Sanjai Kumar2
1
Arthropods/Entomology
National Institute of Allergy and Infectious Diseases, Rockville, MD, United
States, 2FDA, Rockville, MD, United States
(ACMCIP Abstract)
8 a.m. - 9:45 a.m.
8:45 a.m.
CHAIR
APOPTOSIS-RELATED AND INTERFERON-RESPONSIVE TRANSCRIPTS CHARACTERIZE DIFFERENTIAL WHOLE BRAIN
RESPONSES IN RESISTANCE AND SUSCEPTIBILITY TO EXPERIMENTAL CEREBRAL MALARIA
1
2
1
Fiona E. Lovegrove , Sina A. Gharib , Samir N. Patel , W. Conrad
Liles1, Kevin C. Kain1
1
McLaughlin-Rotman Center for Global Health, University of Toronto,
Toronto, ON, Canada, 2University of Washington, Seattle, WA, United States
(ACMCIP Abstract)
9 a.m.
1019
ISOLATION OF HOST RESISTANCE FACTORS TO LIVER STAGE
PLASMODIUM BERGHEI INFECTION BY GENETIC MAPPING
Lígia A. Gonçalves1, Maria M. Mota2, Carlos Penha-Gonçalves1
Instituto Gulbenkian de Ciência, Oeiras, Portugal, 2Instituto de Medicina
Molecular, Lisboa, Portugal
Abdoulaye Diabate
Gabriella Gibson
Natrual Resources Institute, Chatham Maritime, Kent, United Kingdom
8 a.m.
1022
SWARM SEGREGATION IS THE MAIN MECHANISM THAT PREVENTS MATING BETWEEN SYMPATRIC MOLECULAR FORMS
OF ANOPHELES GAMBIAE
Abdoulaye Diabate1, Adama Dao2, Alpha S. Yaro2, Adamou
Alpha2, S. Cheick Traore2, Rodrigo Gonzalez1, Bob Gwadz1,
Tovi Lehmann1
1
Laboratory of Malaria and Vector Research/National Institute of Allergy and
States, 2MRTC, Bamako, Mali
(ACMCIP Abstract)
205
1018
1
Salon IJ
Detailed Program
www.astmh.org
8:15 a.m.
Symposium 164
1023
AUDITORY INTERACTIONS BETWEEN MALES AND FEMALES
OF MEDICALLY IMPORTANT CULEX SPECIES
1
2
2
Gabriella Gibson , Ben Warren , Ian J. Russell
1
Natural Resources Institute, Chatham Maritime, Kent, United Kingdom,
2
University of Sussex, Falmer, Brighton, United Kingdom
8:30 a.m.
1024
A NEW ROBUST DIAGNOSTIC POLYMERASE CHAIN REACTION
(PCR) FOR DETERMINING THE MATING STATUS OF FEMALE
AN. GAMBIAE MOSQUITOES
Kija R. Ng’habi1, Ashley Horton2, Bart GJ Knols3,
Gregory C. Lanzaro2
Larval Source Management Field Trials I
Salon KL
Five major field trials investigating the impact of microbial larvicides on
reducing malaria transmission and clinical malaria have been in progress in
different parts of Africa over the past three years. These studies, supported
by NIH and United States Agency for International Development through
RTI, will help inform policymakers about the value of these interventions
and guide major larval control operations presently underway or planned for
the future. In this session the results of major field studies using microbial
larvicides in The Gambia, Kenya, Eritrea and Tanzania will be presented.
CHAIR
Steve W. Lindsay
Durham University, Durham City, United Kingdom
1
Republic of Tanzania, 2University of California, Davis, CA, United States,
3
Wageningen University and Research Centre, Wageningen, The
Netherlands
8 a.m.
8:45 a.m.
Silas Majambere
1025
COMPARISON OF KAIROMONES UTILIZED BY SEVERAL
MEDICALLY IMPORTANT INSECT AND TICK TAXA
Daniel L. Kline
USDA-ARS, CMAVE, Gainesville, FL, United States
MALARIA CONTROL WITH MICROBIAL LARVICIDES IN RURAL
GAMBIA
Durham University, Durham, United Kingdom
8:30 a.m.
MALARIA CONTROL WITH LARVICIDES IN MWEA IRRIGATION
SCHEME, KENYA
Robert J. Novak
Illinois Natural History Survey, Champaign, IL, United States
9:00 a.m.
1027
8:55 a.m.
A MEANS TO AN END: COMPARATIVE ANALYSIS OF CHROMOSOMAL INVERSIONS FREQUENCY AND DISTRIBUTION IN
THE MAJOR MALARIA VECTORS ANOPHELES GAMBIAE AND
ANOPHELES FUNESTUS ACROSS ECOLOGICALLY DIVERSE
ENVIRONMENTS IN CAMEROON
MALARIA CONTROL USING MICROBIAL LARVICIDES IN
ERITREA
Diego Ayala1, Kenji Ose2, Jean Pierre Agbor3, Carlo Costantini4,
Nora J. Besansky5, Frederic Simard3, Didier Fontenille1
9:20 a.m.
1
Montpellier, France, 2Institut de Recherche pour le Développement, Unité de
Service US140, Orleans, France, 3Organisation de coordination pour la lutte
contre les grandes endémies en Afrique centrale, Yaounde, Cameroon,
4
Bobo-dioulasso, Burkina Faso, 5Center for Global Health and Infectious
Diseases, Department of Biological Sciences, University of Notre Dame,
Notre Dame, IN, United States
Josephat I. Shililu
ICIPE, Nairobi, Kenya
MALARIA CONTROL USING LARVICIDES IN DAR ES SALAAM,
TANZANIA
Gerry F. Killeen
Coffee Break
Franklin Hall Foyer
Thursday, November 8, 2007 9:45 a.m. - 10:15 a.m.
9:15 a.m.
1028
CHROMOSOMAL EVOLUTION IN MALARIA MOSQUITOES OF
SUBGENUS CELLIA
Igor V. Sharakhov, Maria V. Sharakhova, Ai Xia
Virginia Tech, Blacksburg, VA, United States
206
www.astmh.org
11:45 a.m.
1033
Schistosomiasis III - Molecular Biology
IDENTIFICATION BY SUPPRESSION SUBTRACTIVE HYBRIDIZATION OF IMMEDIATE RESPONSE-GENES DOMINANTLY
EXPRESSED IN BIOMPHALARIA GLABRATA SNAILS UPON
EXPOSURE TO SCHISTOSOMA MANSONI INFECTION
Salon AB
10:15 a.m. - Noon
CHAIR
Wannaporn Ittiprasert1, Andre Miller1, Vish Nene2,
Najib El-Sayed3, Jocelyn Celeste Myers1, Matty Knight1
W. Evan Secor
1
Biomedical Research Institute, Rockville, MD, United States, 2University of
Maryland School of Medicine, Baltimore, MD, United States, 3University of
Maryland, College Park, MD, United States
Timothy Yoshino
10:15 a.m.
ROLE OF TGF-BETA IN SCHISTOSOME EGG DEVELOPMENT
Mosquitoes - Vector Biology - Epidemiology III
Edward Pearce
Salon CD
Thursday, November 8, 2007 10:15 a.m. - Noon
10:45 a.m.
CHAIR
1029
Ludmel E. Urdaneta
TRANSCRIPTOME ANALYSIS OF BIOMPHALARIA GLABRATA,
SNAIL HOST OF SCHISTOSOMA MANSONI
Coenraad M. Adema, Cheng-Man Lun, Ben Hanelt
10:15 a.m.
1036
INTEGRATED VECTOR MANAGEMENT FOR THE PREVENTION
OF MALARIA IN WESTERN KENYA: INTERACTIONS OF LARVAL
CONTROL AND INTENSIVE ITN IMPLEMENTATION ON
ANOPHELES GAMBIAE DENSITY
(ACMCIP Abstract)
11 a.m.
1030
Nabie Bayoh1, Edward D. Walker2, John Gimnig3, Francis Mutuku1,
John Vulule1, Mary Hamel4
GENE CLONING AND FUNCTIONAL CHARACTERIZATION
OF A TANDEM-REPEAT GALECTIN FROM CELLS OF THE
BIOMPHALARIA GLABRATA EMBRYONIC (BGE) CELL LINE
1
University of Wisconsin-Madison, Madison, WI, United States
Kenya Medical Research Institute, Kisumu, Kenya, 2Michigan State
University, East Lansing, MI, United States, 3Centers for Disease Control and
Prevention, Atlanta, GA, United States, 4Centers for Disease Control and
Prevention/KEMRI, Kisumu, Kenya
(ACMCIP Abstract)
10:30 a.m.
Nathalie Dinguirard, John Kunert, Timothy P. Yoshino
1037
11:15 a.m.
1031
NOVEL MODULATORY ACTIONS OF SCHISTOSOME CALCIUM
CHANNEL β SUBUNITS ON VOLTAGE-GATED CALCIUM CURRENTS
2
Vicenta Salvador-Recatala , Toni Schneider ,
Robert M. Greenberg1
Alvaro Molina-Cruz, Sara Leszczynski, Lalita Gupta, Sanjeev
Kumar, Randall DeJong, Georges Ndikuyeze, Carolina Barillas-Mury
1
Marine Biological Laboratory, Woods Hole, MA, United States,
University of Cologne, Cologne, Germany
10:45 a.m.
2
1038
11:30 a.m.
1032
IDENTIFICATION AND CHARACTERIZATION OF A R-SMAD
ORTHOLOGUE (SMSMAD1B) FROM SCHISTOSOMA MANSONI
1
2
1
1
Joelle M. Carlo , Ahmed Osman , Edward G. Niles , Wenjie Wu ,
Marcelo R. Fantappie2, Francisco M. Oliveira2, Philip T. LoVerde2
1
2
State University of New York, Buffalo, NY, United States, University of
Texas Health Science Center, San Antonio, TX, United States
INTROGRESSION OF THE CARB77 TRANSGENE INTO A GENETICALLY DIVERSE LABORATORY STRAIN OF AEDES AEGYPTI
FROM TAPACHULA, CHIAPAS STATE, MEXICO
Ludmel Urdaneta-Marquez1, Michael Salasek1, Alexander W.E.
Franz1, Ken E. Olson1, Janine M. Ramsey2, William C. Black1
1
Department of Microbiology, Immunology and Pathology, Colorado State
University, Fort Collins, CO, United States, 2Instituto Nacional de Salud
Publica, Centro de Investigacion de Paludismo, Tapachula, Mexico
207
1
ANOPHELES GAMBIAE GUT FLORA DINAMICS AND
MICROARRAY ANALYSIS OF GUT GENE EXPRESSION IN
RESPONSE TO BACTERIA
Detailed Program
www.astmh.org
11 a.m.
10:30 a.m.
1039
1042
TRANSCRIPTOMIC ANALYSIS AND TEMPORAL EXPRESSION
PROFILING OF THE MIDGUT OF THE SAND FLY LUTZOMYIA
LONGIPALPIS IN BLOOD FEEDING AND INFECTION WITH
LEISHMANIA CHAGASI
A COHORT STUDY TO ASSESS THE NEW WHO JAPANESE
ENCEPHALITIS SURVEILLANCE STANDARDS
Ryan C. Jochim1, Clarissa R. Teixeira2, Regis B. Gomes2, Andre
Laughinghouse2, Dia-eldin Elnaiem2, Jianbing Mu2, Luiz F. Oliveira2,
Jesus G. Valenzuela2
1
1
States, 2National Institute of Allergy and Infectious Diseases, Rockville, MD,
United States
Tom Solomon1, Thi Thu Thao2, Penelope Lewthwaite1, Mong How
Ooi1, Rachel Kneen1, Nguyen Minh Dung2, Nicholas White3
Viral Brain Infections Group, University of Liverpool, Liverpool, United
Kingdom, 2The Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam,
3
University of Oxford-Wellcome Trust Clinical Research Unit, Ho Chi Minh
City, Vietnam
10:45 a.m.
1043
11:15 a.m.
1040
IDENTIFICATION OF MALE SPECIMENS OF CULEX PIPIENS
COMPLEX (DIPTERA: CULICIDAE) MOSQUITOES BY MORPHOMETRIC INVESTIGATION OF THE PHALLOSOMES AND BY
MOLECULAR TECHNIQUES
Yibayiri O. Sanogo1, Chang-Hyun Kim1, Richard Lampman1, Jake
G. Halvorsen1, Adel M. Gad2, Robert J. Novak3
EPIDEMIC CHIKUNGUNYA FEVER, INDIA AND INDIAN OCEAN,
2006: LABORATORY-BASED SURVEILLANCE FOR IMPORTED
CASES, UNITED STATES
Eileen C. Farnon, Amanda J. Panella, Roselyn Hochbein, Olga L.
Kosoy, Janeen J. Laveen, Robert S. Lanciotti, Grant L. Campbell
11 a.m.
1
Illinois Natural History Survey, Champaign, IL, United States, 2Research and
Training Center on Vectors of Diseases, Ain Shams University, Cairo, Egypt,
3
University of Alabama, Birmingham, Division of infectious Diseases, AL,
United States
PERSISTENT SEROPREVALECE OF ANAPLASMA PHAGOCYTOPHILUM IN NEW ENGLAND BLOOD DONORS
Melanie C. Proctor1, David A. Leiby1, Stephanie T. Johnson2,
Richard G. Cable2
1044
1
Clinical Tropical Medicine IV
American Red Cross Holland Laboratory, Rockville, MD, United States,
American Red Cross, Farmington, CT, United States
2
(ACMCIP Abstract)
Salon E
10:15 a.m. - Noon
CHAIR
Tom Solomon
Anastacio Q. Sousa
Federal University of Ceara, Charlottesville, VA, United States
10:15 a.m.
1041
11:15 a.m.
1045
FAILURE OF STANDARD BABESIOSIS THERAPY IN
IMMUNOCOMPROMISED HOSTS
Peter J. Krause1, Ben Gewurz2, David Hill3, Francisco Marty2, Ivo
Foppa4, Edouard Vannier5, Ellen Neuhaus1, Gail Skowren6, Shaili
Gupta7, Richard R. Furman8, Carlo McCalla9, Ed Pesanti1, Mary
Young10, Donald F. Heiman11, Jeffrey A. Gelfand2, Gary Wormser9,
John Dickason2, Samuel R. Telford12, Barry Hartman8, Frank Bia7,
Kenneth Dardick1, Diane Christianson1, Morton Coleman13,
Andrew Spielman2
1
LONG-TERM OUTCOMES OF JAPANESE ENCEPHALITIS
IN BANGLADESH
James J. Sejvar1, Jahangir Hossain2, Marc Fischer3, Emily Gurley2,
Sankar Kuma Saha4, Stephen P. Luby2
1
Centers for Disease Control and Prevention, Atlanta, GA, United
States, 2International Center for Diarrhoeal Disease Research, B,
Dhaka, Bangladesh, 3Centers for Disease Control and Prevention,
Fort Collins, CO, United States, 4Dhaka Medical College Hospital,
Dhaka, Bangladesh
University of Connecticut School of Medicine, Farmington, CT, United
States, 2Harvard University School of Medicine, Boston, MA, United States,
3
Hospital for Tropical Diseases, London, United Kingdom, 4University of
South Carolina School of Medicine, Charleston, SC, United States, 5Tufts
University School of Medicine, Boston, MA, United States, 6Brown University
School of Medicine, Providence, RI, United States, 7Yale University School of
Medicine, New Haven, CT, United States, 8Cornell University School of
Medicine, New York, NY, United States, 9New York Medical College,
Valhalla, NY, United States, 10Georgetown University School of Medicine,
Washington, DC, United States, 11University of Florida School of Medicine,
Boca Raton, FL, United States, 12Tufts University School of Veterinary
Medicine, Grafton, MA, United States, 13Cornell University School of
Medicine, Boston, MA, United States
208
11:30 a.m.
www.astmh.org
10:45 a.m.
1046
CLINICAL FEATURES OF THE HUMAN BARTONELLOSIS (ACUTE
CARRION’S DISEASE) IN THE NORTHERN FOREST OF PERU
Paul E. Pachas1, Jorge A. Chancafe2, Deysi Medina2, Zoila
Villegas3, Lucinda Troyes3, Nelson Solorzano4, Manuel Cespedes5,
Elizabeth Anaya5, Victor Arenas2, Bertha Granda2, Alexander
Canelo3, Luis A. Suarez-Ognio1
1
General Directorate of Epidemiology-Ministry of Health, Lima, Peru, 2San
Ignacio Health Center, Cajamarca Department, Peru, 3Jaen Directorate of
Health, Cajamarca Department, Peru, 4Caraz Hospital, Ancash Department,
Peru, 5National Institute of Health, Lima, Peru
Dina M. Fonseca
Rutgers University, New Brunswick, NJ, United States
11:10 a.m.
CHARACTERIZATION OF MOSQUITO INFECTION AND TRANSMISSION OF VENEZUELAN EQUINE ENCEPHALITIS VIRUS BY
THE EPIDEMIC MOSQUITO VECTOR, AEDES TAENIORHYNCHUS
Darci R. Smith
Detrick, MD, United States
11:45 a.m.
1047
REDUCTION OF INFANT MORTALITY: LESSONS FROM CEARÁ
STATE, NORTHEASTERN BRAZIL (1995-2002)
1
POPULATION GENETICS OF PHENOTYPIC TRAITS IN THE
CULEX PIPIENS COMPLEX
2
3
Anastacio Q. Sousa , Francisca M. Andrade , Telma B. Queiroz ,
Maria P. Martins3, Richard L. Guerrant4
1
Federal University of Ceara, Fortaleza, Brazil, 2UNICEF, Fortaleza, Brazil,
3
Secretariat of Health of Ceara State, Fortaleza, Brazil, 4University of Virginia,
Symposium 168
Intraspecific Variation in Viral and Vector Genetics and
Pathogen Transmission
Salon F
Each speaker will present and discuss case studies on how variation in
pathogen or vector genetics impacts pathogen transmission. The talks will
span a broad range of agents including West Nile virus, dengue virus,
Venezuelan equine encephalitis virus, and malaria; and diverse vectors
including Culex, Aedes, and Anopheles species.
11:35 a.m.
POPULATION GENETICS AND PHYLOGEOGRAPHY OF
ANOPHELES DARLINGI
Jan E. Conn
New York State Department of Health, Albany, NY, United States
American Committee of Molecular, Cellular
and Immunoparasitology (ACMCIP): Molecular
Parasitology II
Salon G
10:15 a.m. - Noon
CHAIR
Donald Harn
CHAIR
Upinder Singh
Laura D. Kramer
Stanford University, Los Altos, CA, United States
Wadsworth Center, Albany, NY, United States
10:15 a.m.
1075
Rutgers University, New Brunswick, NJ, United States
10:15 a.m.
A CONSERVED BASIC GROOVE ON ALDOLASE MEDIATES
MIC2 CYTOPLASMIC TAIL AND F-ACTIN BINDING
INTRODUCTION
G. Lucas Starnes, Miguel St-Jean, Jurgen Sygusch, L. David Sibley
Laura D. Kramer
Washington University, St. Louis, MO, United States
Wadsworth Center, Albany, NY, United States
10:20 a.m.
HOW CAN POPULATION GENETIC STUDIES ADD TO THE
KNOWLEDGE OF VECTOR DISEASES? THE CASE OF DENGUE
AND CHIKUNGUNYA VECTORS
Anna-Bella Failloux
Institut Pasteur, Paris, France
10:30 a.m.
1076
A POTENTIAL ROLE FOR GP34, A GPI-ANCHORED THEILERIA
SURFACE PROTEIN, IN THE SYNCHRONIZATION OF PARASITE
AND HOST CELL DIVISION
Gongda Xue, Martina Peyer, Conrad von Schubert, Pascal
Hermann, Peter Buetikofer, Adrian Hehl, Dirk A. Dobbelaere
University of Bern, Bern, Switzerland
209
Dina M. Fonseca
Detailed Program
www.astmh.org
10:45 a.m.
11:45 a.m.
1048
IDENTIFICATION OF DEVELOPMENTALLY REGULATED GENES
IN ENTAMOEBA HISTOLYTICA
Gretchen M. Ehrenkaufer, Upinder Singh
1052
A DNA VACCINE ENCODING A SAND FLY SALIVARY YELLOW
RELATED PROTEIN (LJM11) CONFERS PROTECTION AGAINST
CHALLENGE WITH L. MAJOR IN THE PRESENCE OF L. LONGIPALPIS SALIVARY GLAND HOMOGENATE
(ACMCIP Abstract)
Luiz F. Oliveira, Regis B. Gomes, Shaden Kamhawi, Clarissa
Teixeira, Dia-eldin Elnaiem, Jesus G. Valenzuela
11 a.m.
1049
CYSTEINE PROTEASE ACTIVITY IN SCHISTOSOMA MANSONI
RESISTANT AND SUSCEPTIBLE BIOMPHALARIA GLABRATA
SNAILS
(ACMCIP Abstract)
Jocelyn C. Myers1, Wannaporn Ittiprasert1, Andre’ Miller1,
Clarence M. Lee2, Matty Knight1, Nithya Raghavan1
Malaria - Biology and Pathogenesis II
1
Salon H
Biomedical Research Institute, MD, United States, 2Howard University,
Washington, DC, United States
(ACMCIP Abstract)
10:15 a.m. - Noon
CHAIR
11:15 a.m.
1050
Dapa A. Diallo
MRTC/DEAP/FMPOS, Bamako, Mali
IDENTIFICATION OF IMMEDIATE RESPONSE - GENES DOMINANTLY EXPRESSED IN BIOMPHALARIA GLABRATA SNAILS
UPON EXPOSURE TO SCHISTOSOMA MANSONI INFECTION
Abdoulaye Djimde
Wannaporn Ittiprasert1, Andre’ Nathaniel Miller1, Vish M. Nene2,
Najib M. El-Sayed3, Jocelyn Celeste Myers1, Matty Knight1
10:15 a.m.
Biomedical Research Institute, Rockville, MD, United States, 2Institute of
Genome Sciences and Development of Microbiology and Immunology,
3
Center for Bioinformatics and Computational Biology, University of
Maryland, College Park, MD, United States
1053
1
(ACMCIP Abstract)
1051
ANTI-TRANSMISSION DNA VACCINE FOR SCHISTOSOMIASIS
JAPONICA IN CHINA
Akram A. Da’Dara1, Li Yuesheng2, Tie Xiong2, J. Zhou2, Gail M.
Williams3, Donald P. McManus4, Feng Zheng5, Xinling Yu2, Donald
A. Harn1
Harvard School of Public Health, Boston, MA, United States, 2Hunan
Institute of Parasitic Diseases, Yue Yang City, China, 3University of
Queensland, Herston, Australia, 4Queensland Institute of Medical Research,
Herston, Australia, 5National Institute of Parasitic Diseases, Shanghai, China
(ACMCIP Abstract)
Lindsey Turnbull1, Nicholas Connors1, Karl Seydel2, Danny Milner3,
Linda Kalilani4, Miriam Laufer5, Christopher Plowe5, Terrie Taylor2
1
11:30 a.m.
1
MULTIPLY PARASITIZED ERYTHROCYTES ARE ASSOCIATED
WITH INCREASED SEVERITY OF MALARIA
Blantyre Malaria Project, Blantyre, Malawi, 2College of Osteopathic
Medicine, Michigan State University, East Lansing, MI, United States,
3
Brigham and Women’s Hospital, Boston, MA, United States, 4University of
Malawi College of Medicine, Blantyre, Malawi, 5University of Maryland
School of Medicine, Baltimore, MD, United States
10:30 a.m.
1054
IN UTERO SELECTION AT THE FLT1 LOCUS IN A
MALARIA-ENDEMIC AREA
Atis Muehlenbachs1, Michal Fried2, Jeff Lachowitzer2, Theonest K.
Mutabingwa3, Patrick E. Duffy2
1
University of Washington, Seattle, WA, United States, 2Seattle Biomedical
Research Institute, Seattle, WA, United States, 3National Institute of Medical
Research, Dar es Salaam, United Republic of Tanzania
210
10:45 a.m.
11:30 a.m.
1055
1058
IP-10, APOPTOTIC AND ANGIOGENIC FACTORS ASSOCIATED
WITH MORTALITY OUTCOMES IN CEREBRAL MALARIA
PATIENTS IN INDIA
1
www.astmh.org
2
3
BLOOD GROUP O PROTECTS AGAINST SEVERE PLASMODIUM
FALCIPARUM MALARIA
J. Alexandra Rowe1, Anne-Marie Deans1, Mahamadou A. Thera2,
Kirsten E. Lyke3, Abdoulaye K. Kone2, Dapa A. Diallo2, Ahmed
Raza1, Oscar Kai4, Kevin Marsh4, Christopher V. Plowe3, Joann M.
Moulds5
4
Vidhan Jain , Nana Wilson , Henry Armah , Jon E. Tongren ,
Pradeep K. Joel5, Mrigendra P. Singh5, Avinash C. Nagpal5,
A. P. Dash5, Venkatachalam Udhayakumar6, Neeru Singh5,
Jonathan K. Stiles2
1
1
University of Edinburgh, Edinburgh, United Kingdom, 2University of
Bamako Faculty of Medicine, Bamako, Mali, 3University of Maryland School
of Medicine, Baltimore, MD, United States, 4KEMRI/Wellcome Laboratories,
Kilifi, Kenya, 5Lifeshare Blood Center, Shreveport, LA, United States
2
National Institute of Malaria Research (ICMR), Jabalpur, India, Morehouse
School of Medicine, Atlanta, GA, United States, 3University of Pittsburgh,
Pittsburgh, PA, United States, 4Centers for Disease Control and Prevention,
Atlanta, GA, United States, 5National Institute of Malaria Research (ICMR),
Jabalpur, India, 6Centers for Disease Control and Prevention, Atlanta, GA,
United States
11:45 a.m.
1059
(ACMCIP Abstract)
α+-THALASSAEMIA PROVIDES A HAEMATOLOGICAL
ADVANTAGE AGAINST MALARIA
11 a.m.
1056
Freya J. Fowkes1, Stephen J. Allen2, Angela Allen2, Michael P.
Alpers3, David J. Weatherall2, Karen P. Day1
SUPPRESSION OF MACROPHAGE MIGRATION INHIBITORY
FACTOR (MIF) IN CHILDREN WITH SEVERE MALARIAL ANEMIA: ROLE OF MONOCYTE ACQUISITION OF HEMOZOIN
1
New York University School of Medicine, Department of Medical
Parasitology, New York, NY, United States, 2The Weatherall Institute of
Molecular Medicine, University of Oxford, Oxford, United Kingdom, 3Papua
New Guinea Institute of Medical Research, Goroka, Papua New Guinea
Gordon A. Awandare1, Yamo Ouma2, Collins Ouma2, Tom Were2,
Richard Otieno2, Christopher Keller3, Gregory Davenport1, James
Hittner4, John Vulule5, Robert Ferrell6, John Michael Ong’echa2,
Douglas Perkins1
1
University of Pittsburgh Graduate School of Public Health, Department
of Infectious Diseases and Microbiology, Pittsburgh, PA, United States,
2
University of Pittsburgh/KEMRI Laboratories of Parasitic and Viral Diseases,
Kisumu, Kenya, 3Lake Erie College of Osteopathic Medicine, Erie, PA, United
States, 4Department of Psychology, College of Charleston, Charleston, SC,
United States, 5Kenya Medical Research Institute, Kisumu, Kenya, 6University
of Pittsburgh Graduate School of Public Health, Department of Human
Genetics, Pittsburgh, PA, United States
Ectoparasite-Borne Diseases
Salon IJ
10:15 a.m. - Noon
CHAIR
Maria Diuk-Wasser
11:15 a.m.
1057
Lucy M. Ndip
University of Buea, Buea, Cameroon
IMPACT OF ARTMISININ-BASED COMBINATION THERAPY ON
MALARIA TRANSMISSION IN MALI
10:15 a.m.
Bakary Fofana, Adama Dao, Cheick Omar Kone, Bakary Sidibe,
Sekou Toure, Sekou Koumare, Demba Dembele, Abdoulaye Toure,
Ogobara K. Doumbo, Abdoulaye A. Djimde
1060
Maria Diuk-Wasser1, Gwenael Vourc’h2, Anne Gatewood1, Paul
Cislo1, Roland Geerken1, Sarah Yaremych-Hamer3, Michelle
Rowland4, Roberto Cortinas5, Jean Tsao3, Uriel Kitron4, Joseph
Piesman6, Durland Fish1
1
Yale University, New Haven, CT, United States, 2Institut National de la
Recherche Agronomique (INRA), St. Genes Champanelle, France, 3Michigan
State University, East Lansing, MI, United States, 4University of Illinois,
Urbana-Champaign, IL, United States, 5University of Minnesota, Saint Paul,
MN, United States, 6Centers for Disease Control and Prevention, Fort Collins,
CO, United States
211
MODELING THE DISTRIBUTION OF THE HOST-SEEKING
NYMPHAL I. SCAPULARIS TICKS IN THE USA USING CLIMATE
AND LANDSCAPE PREDICTORS
Detailed Program
www.astmh.org
10:30 a.m.
Symposium 172
1061
IMMUNITY TO SALIVA AT THE TICK-HOST INTERFACE: IDENTIFICATION OF IXODES SCAPULARIS SALIVARY PROTEINS ELICITING A CELLULAR IMMUNE RESPONSE
Jennifer M. Anderson1, Nathan J. Miller2, Thomas N. Mather2,
Jerrold M. Ward1, Jesus G. Valenzuela1
1
National Institutes of Health, Rockville, MD, United States, 2University of
Rhode Island, Kingston, RI, United States
10:45 a.m.
1062
METHODOLOGICAL CONSIDERATIONS IN DESCRIBING THE
POPULATION DYNAMICS OF DEER TICKS ON WHITE-FOOTED
MICE
Elissa V. Klinger1, Ivo M. Foppa2, Heidi K. Goethert1,
Sam R. Telford1
1
Cummings School of Veterinary Medicine, Tufts University, North
Grafton, MA, United States, 2Arnold School of Public Health, Columbia, SC,
United States
11 a.m.
1063
Larval Source Management Field Trials II
Salon KL
Five major field trials investigating the impact of microbial larvicides on
reducing malaria transmission and clinical malaria have been in progress in
different parts of Africa over the past three years. These studies, supported
by NIH and United States Agency for International Development through
RTI, will help inform policy makers about the value of these interventions
and guide major larval control operations presently underway or planned for
the future. In this session, recent work on integrated vector management
using microbial larvicides and other interventions will be discussed, together
with a case study on the cost-effectiveness of microbial larvicides.
CHAIR
Steve W. Lindsay
10:15 a.m.
SPATIAL ASPECTS OF MALARIA CONTROL WITH LARVICIDES
AND ENVIRONMENTAL MANAGEMENT IN DAR ES SALAAM,
TANZANIA
Marcia C. de Castro
IDENTIFICATION OF A NATURAL FOCUS OF TULAREMIA
TRANSMISSION USING GIS MAPPING OF INFECTED
DERMACENTOR VARIABILIS
Heidi Goethert, Sam Telford
Tufts University School of Veterinary Medicine, N. Grafton, MA,
United States
10:40 a.m.
INTEGRATED VECTOR MANAGEMENT WITH LARVAL AND
ADULT MOSQUITO CONTROL IN THE KAKAMEGA
HIGHLANDS, KENYA
Ulrike Fillinger
11:15 a.m.
1064
11:05 a.m.
Lucy M. Ndip
ENVIRONMENTAL MANAGEMENT IN THE KENYAN
HIGHLANDS
University of Buea, Buea, Cameroon
Andrew K. Githeko
EHRLICHIOSES IN CAMEROON
11:30 a.m.
1065
RISK OF SPOTTED FEVER GROUP RICKETTSIA INFECTION TO
U.S. MILITARY PERSONNEL
Ju Jiang1, Paul C. Graf1, Ellen Y. Stromdahl2, Allen L. Richards1
Naval Medical Research Center, Silver Spring, MD, United States, 2US Army
Center for Health Promotion and Preventive Medicine, Edgewood Area of
Aberdeen Proving Ground, MD, United States
11:30 a.m.
COST-EFFECTIVENESS OF MALARIA CONTROL USING MICROBIAL LARVICIDES
Eve Worrall
Liverpool Associates in Tropical Health, Liverpool, United Kingdom
1
Noon
ASTMH 56th Annual Meeting Adjourns
11:45 a.m.
1066
SEE YOU NEXT YEAR IN NEW ORLEANS, LOUISIANA!
HUMAN ANTIBODY-REACTIVE EPITOPES ON THE CONSERVED
47 KDA ANTIGEN OF ORIENTIA TSUTSUGAMUSHI AND THEIR
SIMILARITY TO EPITOPES ON HUMAN SERINE PROTEASE
Hua-Wei Chen1, Hui Wang1, Gregory A. Dasch2, Wei-Mei Ching1
1
Naval Medical Research Center, Silver Spring, MD, United States, 2Centers
for Disease Control and Prevention, Atlanta, GA, United States
212
Author Index
Important Note: The number(s) following author name refer to the abstract number.
A
A-nuegoonpipat, Atchareeya 107
Abanobi, Okwuoma C. 100
Abbassy, Magda M. 61
Abdelhamid, Mohamed 731
Abdukhalilova, Gulnara K. 744
Abdul Rahman, Sohayati 954
Abdulla, Maha-Hamadien 292
Abdulla, Salim 95, 342, 529, 537,
633, 676, 830
Abel, Jason A. 614
Abo-Shehada, Mahmoud 64, 397
Aboi, Madaki J. K. A. 494
Abot, Stephen 304
Abraham, David 89
Abrams, Jerry 102
Abu Ayyash, Luma 402, 889
Abudho, Bernard 310
Achan, Jane 705
Acharya, Deepak B. 92
Achee, Nicole L. 60, 63, 332, 583
Acholonu, Alex D. W. 280
Acosta, Luz 70, 335
Acuna-Soto, Rodolfo 732
Adam, Ishag 635
Adama, Soumahoro 496
Adams, A. P. 278
Adams, David P. 498
Adedapo, Aduragbenro D. A. 99,
414
Adedeji, Ahmed A. 88, 527
Adegbola, Richard 384
Adelman, Zach N. 643
Adema, Coenraad M. 285, 299,
1029
Ademowo, George O. 547
Ademowo, Olusegun G. 155, 179,
495
Adeyefa, Christopher A. O. 994
Adimi, Farida 185
Adjei, Ohene 388, 389
Adjei, Samuel 504, 637
Adjuik, Martin 103
Adler, Adam J. 62
Adu, Festus D. 994
Aeby, Eric 1070
Afolabi, Bangmboye 692
Agawo, Maurice O. 598
Agbenyega, Tsiri 651
Agbor, Jean Pierre 1027
Ager, Arba L. 173, 174, 822
Agnamey, Patrice 634, 717
Agnandji, Selidji 10
Agola, Eric L. 336
Agrawal, D. 378
Agrawal, N. 378
Agrawal, Swati 1069
Aguiar, Joao C. 217, 574
Aguiar, Marli 997
Aguilar, Patricia V. 927, 994
Aguilar-González, Sonia 272
Aguinaga, Juan G. 371
Aguirre, A. Alonso 467
Ahamed, Shakil 966
Ahmed, Be-Nazir 281, 955
Ahmed, R. 341
Ahmed, Sabeena 609
Ahn, Myoung-Hee 607
Ahn, Sun-Young 157
Ahn, Yvonne 680
Ahouidi, Ambroise D. 1021
Aide, Pedro 8, 9, 306, 572
Aiki-Raji, Comfort O. 994
Aimaku, Christopher O. 179
Aitken, Elizabeth 808
Ajariyakhajorn, Chuanpis 2
Ajayi, Ikeoluwapo O. 404, 406, 407
Akaki, Mayumi 366
Akanbi, Mathew O. 547
Akanbi, Olusegun M. 155
Akanmori, Bartholomew D. 192,
195, 198
Akhwale, Willis 338, 339, 351, 546
Akida, Juma A. 842
Akinsola, Adebayo 384
Akinyi, Sheila 806
Akkoclu, Gulgun 900
Akman-Anderson, Leyla 977
Ako, Berenger A. 496
Akogbeto, Martin 230, 621
Akpogheneta, Onome 302
Akter, Selim 636
Al-Ali, Faiza M. 79
Al-Ani, Mohammad S. Ahmad. 91
Al-Shelahi, Fatima A. 79
Alaii, Jane 339
Alam, Mohammad T. 201, 528, 877
Alangaden, George 719
Alarcon-Chaidez, Francisco J. 62
Albanese, Chris 146
Albers, Anna 389
Albonico, Marco 180
Albright, Rebecca G. 659
Alcantara, Leda 380
Aldstadt, Jared 264
Alera, Maria Theresa 760
Alessiani, Mario 73
Alexander, Neal 358
Alger, Jackeline 787
Ali, Ehsan 77
Ali Khan, Wasif 636
Alibert, Sandrine 818
Alisjahbana, Bachti 766
Alkeilani, Maysaa 91
Allan, Sandra A. 254
Allary, Marina 367
Allen, A. 207
Allen, Angela 1059
Allen, Linda 929
Allen, Stephen J. 1059
Allicock, Orchid M. 616
Allison, Geneve 609
Almela, Maria J. 511, 826
Almendares, Olivia 787
Almeras, Lionel 238
Almirón, Walter R. 398
Alonso, E. 511
Alonso, Pedro L. 8, 9, 306, 572
Alpers, Michael P. 1059
Alpha, Adamou 1022
Alphonsus, Kal 422
Altamura, Louis A. 612
Althabe, Fernando 787
Aluma, Simon 96
Aluvihare, Chana 240
Alvarez, Angela 512, 513
Alvarez, Jorge I. 34
Aly, Ahmed S. I. 364
Ama-Moor, Vicky 717
Amador, Domingo 787
Amador, Juan Jose 110
Ambrosio, Javier R. 273
Amemasor, Solomon 637
Amengo-Eteego, Seeba 726
Ampudia, Elizabeth 577
Anantapreecha, Surapee 107
Ananth, Cande 703
Anaya, Elizabeth 1046
Anders, Robin 300, 551, 554
Anderson, John F. 263, 590, 646
Anderson, Jennifer M. 1061
Anderson, Karen S. 823
Anderson, Michelle 643
Anderson, Robert 41
Andersson, Neil 645
Andrade, Christy C. 660
Andrade, Francisca M. 1047
Andreadis, Theodore 257, 263, 282,
602
Andrews, Kathy T. 165
Andrzejewski, Christopher 501, 638
Angele, Olivier 81
Angov, Evelina 12, 161, 215, 219,
220
Angulo-Barturen, Iñigo 512, 513
Annan, Zeinab 38
Ansong, Daniel 637
Anstead, Gregory M. 739
Anstey, Nick 354, 486, 544, 701
Anthony, Gabriel A. 720
Anthony, Robert 983
Anto, Francis 103, 597, 746
Antonelli, Lis R. V.. 312
Antonio-Nkondjio, Christophe 872
Anumudu, Chiaka 193, 524
Anyamba, Assaf 989
Anyona, Samuel B. 578
Anyorigiya, Thomas 103
Apara, A.U. 280
Aphasizhev, Ruslan 1074
Aphasizheva, Inna 1074
213
Apiwathnasorn, Chamnarn 232
Aponte, John J. 8, 9, 306, 572
Aponte, Samanda 837
Appawu, Maxwell A. 597
Apperson, Charles 402, 589, 889
Aradaib, Imad 372
Arai, Meiji 208
Arai, Satoru 958
Arama, Charles 324
Aranda, Miguel 738
Araujo Castillo, Roger V. 19, 683,
728
Araz, Engin 431
Arboleda, Margarita 758
Arcos-Teran, Laura 400
Ardelli, Bernadette F. 776
Arenas, Victor 898, 1046
Arévalo, Jorge 475
Arevalo-Herrera, Myriam 43
Arguello, D. F. 112
Arias, Jose 738
Arias, Patricia 33
Ariey, Frederic 811, 831
Arlian, Larry 433
Armah, George E. 439, 746
Armah, Henry 804, 1055
Armando, Gonzalez 33
Armien, Blas 28, 118, 764
Armijos, Veronica 459
Armstrong, Adam 905, 906
Armstrong, Philip M. 257, 263, 282
Arnathau, Céline 38
Arnold, Shannon 965
Aronson, J.F. 278
Aronson, Naomi E. 379
Arostegui, Jorge 645
Arriens, Sandra 785
Arrigo, N.C. 278
Arrigo, Nicole C. 615
Arriola, C. Sofia 30
Arrospide, Nancy 972
The ART Costing Study Team 704
Arterburn, Jeffery 923
Arvay, Melissa 439
Arvelo, Wences 17
Asante, Kwaku P. 726
Asare, Kwaku 804
Asgary, Ramin G. 408
Asghar, Rai 678
Ashley, Elizabeth 974
Ashorn, Per 808
Ashraf, Mohammad 149
Ashraf, Yusra Pervaiz 678
Asmah, Richard H. 746
Asnis, Deborah 77, 813, 902
Asoala, Victor 597
Assis, Juliana d. 482
Assmar, Mehdi 474
Astete, Helvio 623
Astete, H. 930
Atibu, Joseph 703
Author Index
Atkinson, Peter A. 945
Atuguba, Frank 103
Aubry, Maite 449
Audcent, Tobey A. 427
Auguste, Albert J. 616, 688
Auld, Andrew 736
Auliff, Alyson 187
Avendaño, Adrian 894
Avery, Mitchell A. 639, 862
Avery, Melissa F. 890
Avery, Thomas 654
Aviles, William 86, 110
Avril, Marion 49, 580
Awandare, Gordon 20, 200, 321,
548, 549, 694, 707, 1056
Awes, Abdulkadir A. 546
Awinie, Elizabeth 726
Awobode, Henrietta O. 193
Awobusuyi, Jacob O. 651
Awono-Ambene, Parfait 38, 872
Ayala, Diego 1027, 1035
Ayala, Marta 797
Ayala, Virgilio 403
Ayala-López, Aurimar 109, 458
Ayanful, Ruth 211
Aybar, Viterbo 30
Ayede, Idowu 193
Azab, Mohamed A. 914
B
B, Bernadin 496
Ba, Yamar 466
Babu, Subash 666
Babur, Cahit 431
Bacellar, Olivia 312
Bacon, David J. 203, 416, 475, 525,
526
Badiane, El-Hadji 935
Badusche, Marlis 949
Bagayoko, Mamadou W. 508, 856
Bage, Jose T. 476
Baggett, Henry 327, 329, 330, 331,
908, 911, 915
Bagheri, Farideh 474
Bai, Ying 330, 331, 908
Baja, Abdullah 676, 830
Bakare, Adekunle A. 621
Baker, Anthony 713
Baker, Joanne 187
Baker, Murray 692
Baker, Virginia S. 692
Balabaskaran, Praveen 855, 857,
859
Balakathiresan, Nagaraja
Sethuraman 946
Balbino, Valdir Q. 397
Balcaitis, Stephanie 580
Balcioglu, Cuneyt 791
Balderrama, M 1001
Baldwin, Carson 125
Balkan, Suna 974
Balkin, E. Asher 139
Ballou, Ripley 8, 9, 10, 218, 572,
578
Balmaseda, Angel 25, 110, 645,
684
Balogun, Tunde 88, 527
Balsitis, Scott 6, 116, 117
Bamgboye, Afolabi 99, 406, 407
Banania, Glenna 304
Banda, Cesar A. 541
Bandi, Claudio 389
Banfield, Christine E. 297
Baniecki, Mary Lynn 652, 935, 821
Banu, Shakila 281, 955
Barban, Veronique 443
Barbe, Jacques 818
Barbollat, Laetitia 973
Barbosa, Arnoldo 9
Barbosa-Solomieu, Valérie 441, 455
Baret, Eric 818
Barillas-Mury, Carolina 39, 243,
885, 941, 1037
Barker, Christopher M. 584
Barker, Robert 652
Barnett, Adrian G. 290
Barnor, Jacob S. 275
Barnwell, John 338, 339, 806
Barón, Olga 886
Barre, Jerome 716
Barennes, H. 1005
Barrett, Alan D. T. 660
Barron, Eduardo A. 29
Bart, Jean-Mathieu 377
Barth, Erin N. 555
Barthel, Robert V. 76
Bartholomay, Lyric C. 953
Bartkovjak, Marian 711
Barzaga, Naile 813
Basáñez, María-Gloria 385, 772,
773
Basler, Christopher F. 927, 994
Bassat, Quique 8, 572
Bassirika, Issiaka 496
Bastos, Melissa S. 697
Bates, Paul 792
Bathini, Nagendrababu 63
Baton, Luke A. 40
Batsa, Linda 388, 389
Battelli, Giorgio 73
Batty, Kevin T. 501, 638, 1007
Baus, Esteban G. 400
Bausch, Daniel G. 186, 259
Bayard, Vicente 118
Bayat, Babak 44
Bayoh, M N. 587, 595
Bayoh, Nabie 1036
Beach, Raymond 175
Beasley, David W. C. 660
Beatty, Mark E. 768
Beatty, P. Robert 6, 116, 117
Beaty, Barry 641, 892, 893, 932
Bebell, Lisa 340, 706
Becerra-Artiles, Aniuska 24
Beck, Hans-Peter 973
Becker-Dreps, Sylvia I. 228
Beckett, Charmagne 115
Beckham, Simone 433
Beckius, Miriam 715
Beerntsen, Brenda 490, 493, 798,
861
Beeson, James G. 300, 301, 550,
551, 552, 554
Beesoon, Sanjay 690
Begum, Ramie H. 202
Behets, Frieda 228
Behr, Charlotte 195, 198
Bei, Amy K. 163, 1021
Beier, John C. 894, 1026
Bejarano, Zulma 837
Belizán, José 787
Bell, David J. 1003
Bell, Jeffrey A. 880, 883
Bell, Christine E. 175
Beltran, Manuela 756
Beltrán-Alzate, Juan C. 78
Benante, John Paul 63
Benitez, Jesus 796
Benjamin, Seleena 897
Bennett, Adam 177, 184, 560
Bennett, Corey J. 661
Bennett, Kent 1008
Bennett, Shannon N. 958
Bennuru, Sasisekhar 665
Bergel, Eduardo 787
Bergman, Lawrence W. 802
Bergmann-Leitner, Elke S. 12, 161,
215, 220
Berman, Josh 1001
Bern, Caryn 627, 786
Bernabe, Antonio 680
Bernal, Maruja 750
Bernal, Oscar 974
Bernard, Kristen A. 659, 661
Bernard, Nicholas 301
Bernhard, Sonja 476
Bernhardt, Scott A. 641
Berrada, Zenda L. 50
Bertholet, Sylvie 141
Besansky, Nora J. 1027, 1035
Bessoff, Kovi 756
Bethel, Jeffrey 469
Betley, Beverly A. 517
Beverley, Stephen M. 630
Bhalla, Ashish 432
Bharti, Praveen K. B. 201
Bhattacharjee, Apurba K. 63, 503,
656, 817, 819
214
Bhoi, Sanjeev 410, 742
Bhonsle, Jayendra B. 656, 817
Bia, Frank 1045
Biddle, Andrea K. 228
Bilenge, Constantin M. Mia. 476
Bin Nisar, Yasir 678
Binka, Fred 439, 746
Birnbaum, Ron A. 631
Birren, Bruce W. 162, 368
Biru, Estifanos 700, 849
Bishar, Rima 741
Bixby, Lisa M. 1072
Björkman, Anders 837
Black, Carla L. 307, 310
Black, William C. 232, 625, 626,
641, 867, 1038
Blackley, Shanley 3
Blair, Carol D. 231, 279, 455, 641
Blair, Patrick 681, 766
Blaney, Joseph E. 124, 347
Blank, Lydia R. 96
Blanton, Elizabeth 15
Blanton, Ronald 296
Blaze, Marie 356
Blazes, David L. 19, 104, 683, 728,
903
Bledzka, Alicja 781
Block, Karla 345
Bloland, Peter B. 529, 633, 676,
830
Blum, Lauren 933
Boakes, Eve 773
Boakye, Daniel A. 386, 596
Bob Sakha, Ndeye 831
Bockarie, Moses 358
Bodhidatta, Ladaporn 744
Boelaert, Marleen 481, 794
Boggiatto, Paola M. 142
Boivin, Jean-Francois 383
Boivin, Michael J. 695
Bojang, Kalifa 1004
Bolaji, Olayinka M. 88, 527
Bolarte, Jose 104, 728
Bolás-Fernández, Francisco 273
Bomlitz, Larisa 708
Bond, Vincent 804
Bonelo, Anilza 759
Boni, Maciej 532
Bonjardim, Cláudio A. 450
Booker, Michael L. 824
Boonpradit, Pornsiri 107
Boonti, Thum 586
Bopp, Cheryl 15
Boppana, Venkata D. 62
Bora, Hema 528
Borad, Anoli J. 609
Borchert, Nadine 985
Borrini, Katty 627
Borrmann, Steffen 651
Borrow, Ray 384
Author Index
Borstnik, Kristina 653
Bosch, Irene 24
Bosio, Christopher 867, 912, 993
Botero, Sebastian 983
Boufana, Belchis 71
Bounlu, Khanthong 104
Bourgoin, Catherine 238
Bourguinat, Catherine 776
Boussinesq, Michel 773, 776
Bouzahzah, Boumediene 146
Bouzaidi-Tiali, Nabile 1070
Bowen, Anna 17
Bowen, Richard A. 660
Bowman, D. D. 399
Bowman, Natalie M. 786
Boykin, David 605
Bradamantis, Florelle 81
Bradley, David J. 42
Braga, Érika M. 697
Braga-Neto, Manuel B. 748, 753
Braig, Henk R. 318
Branch, OraLee H. 203, 727, 847,
850
Brando, Clara 45
Brandon, Michelle C. 234
Brandt, Jef 33
Brandt, Walter 48
Brasky, K. M. 278
Brasov, Ioana 483
Brasseur, Philippe 634, 717, 1005
Brater, D. C. 520
Brattig, Norbert 362, 389, 985
Brault, Aaron C. 660
Braunstein, Vicki L. 146
Bravo, Carmen 513
Brega, Sarah 973
Breiman, Robert 15, 619
Brelsfoard, Corey L. 437
Breman, Joel G. 224, 534
Breña, Judith P. 381
Brengues, Cécile 230
Brennan, Patrick J. 78
Brent-Kirk, Afiya 12, 219
Brewer, Christina M. 880
Breysse, Patrick N. 962
Briceno, Ireneo 583
Briceno, Marnie R. 827, 828
Bridges, Mickey 55
Brieger, William 178
Brindley, Paul J. 289, 1010
Bringaud, Fréderic 1068
Brinning, Douglas 928
Britch, Seth 262, 989
Brito, Cristiana F. Alves. 568, 570
Brito, Gerly A. C. 748
Brito, João R. M,. 745
Bronzan, Rachel 530
Brooks, Mohammed 535
Brown, Charles 211
Brown, Emily M. 998
Brown, Heidi 256, 602
Brown, Joe 53
Brown, James F. 298
Brown, Jessica M. 944
Brown, Mark R. 947
Brown, Ryan P. 642
Brown, Vincent 725
Bruder, Joseph T. 11, 48, 304, 581
Bruhn, Kevin W. 150, 631
Brun, Reto 605
Brunetti, Enrico 72, 73, 74, 373,
374
Bryant, Bart 231
Bryant, Juliet E. 1
Buathong, Rome 960
Buchy, Philippe 26
Buck, Gregory A. 440
Bucyibaruta, Blaise 734
Buekens, Pierre 473, 787
Buetikofer, Peter 1076
Buguliskis, Jeff 531
Bührlen, Martina 637
Bujard, Hermann 194
Bulla, Lee A. 825, 887
Buluma, Robert 546
Bulyk, Martha 1073
Bundy, Don A. P. 133
Bungiro, Richard 628
Burbelo, Peter B. 135
Burdan, L 544
Burga, Rosa 750
Burgess, Steven J. 655
Burgess, Timothy 115, 681, 766
Burkhard, Peter 45
Burkom, Howard 104
Burkot, Thomas R. 464, 890
Burnette, W N. 102
Burns, Jr., James M. 320, 802
Burri, Christian 476
Busch, Wibke 637
Büscher, Philippe 481
Bustamante, Dulce M. 121, 403
Bustamante, Juan M. 669, 1072
Butler, Ashley 125
Butman, Bryan T. 48
Buttaro, Caitlin 1014
Büttner, Dietrich W. 389
Büttner, Marcelle 389
Buzetti, Wilma A. Starke. 482
Bwanika, John B. 96
Byarugaba, Justus 352
Bystryn, Jean-Claude 46
C
Cable, Richard G. 1044
Cabrera, Lilia 749, 786
Caccone, Adalgisa 872
Cafferata, María Luisa 787
Caffrey, Conor R. 292, 293
Cahill, John 405
Cajal, Silvana 89
Caldeira, Roberta L. 294
Calderon, Carmen 35
Calderon, Maritza C. 749
Calderon-Arguedas, Olger 894
Calderon-Martinez, Jose Joaquin
893
Calderwood, Stephen 18, 609
Calisher, Charles H. 932
Calvert, Amanda E. 1
Calvo, Sarah 489
Cama, Vitaliano 266
Camacho-Nuez, Minerva 106
Camargo, Simone 333
Camino, I. 511
Campanella, Richard 1034
Campbell, Grant L. 1043
Campbell, Robert K. 477
Campos, Cornelio 118
Canelo, Alexander 738, 1046
Canfield, Craig J. 173, 174
Cantin, Beth Ann 782
Cantin, Greg T. 370
Cao, Q.T. 207
Cao-Lormeau, Van-Mai 449
Capeding, Maria Rosario 344
Cappello, Michael 628
Caram, Mariana 28, 350, 764
Caray, C. 930
Carcamo, Alvaro 645
Carcamo, Cesar 206
Cardenas, Rocio 1000
Cardinal, Marta V. 394
Cardona, William 886
Cardona-Castro, Nora M. 78
Caridha, Diana 502
Carlo, Joelle M. 1032
Carlone, George 384
Carlos, Daniela C. 137
Carlson, Jonathan O. 625
Carlton, Jane 850
Carr, Kathleen W. 618
Carr, Roxanne 90
Carrington, Christine V. F.. 616, 688
Carrión, R. 930
Carrion, Jr., R. 278
Carroll, Darin S. 614, 991
Carroll, Ryan W. 807
Carter, Terrell 10
Carvalho, Edgar 312
Carvalho, Eunice B. 748
Carvalho, Edgar M. 283, 380
Carvalho, Luzia H. 570
Carvalho, Omar S. 294
Carvalho-Queiroz, Claudia 291
Casares, Sofia 581
Casseb, Samir M. 755
Castañeda, P. 511
215
Castelan-Martínez, Osvaldo D. 188
Castellanos, Alejandro 610
Castellanos, Angélica M. 571
Castellanos-Cuervo, Paula 400
Castelletto, Michelle L. 984
Castelli, Federica 374
Castellini, Meryl 531
Castillo, Leticia 28, 764
Castillo, Rafael 269, 270, 271, 272
Castillo, Yesenia 33
Castillo-Bocanegra, Rafael 273
Castro, Fanny 884
Castro, Ibraim C. 748, 752
Castro, Luiza A. 931
Castro, Marcia C. 227, 261, 845,
848, 851
Castro, Nina 266
Castro, Neviton 283
Castro, Xochitl 403
Cator, Lauren J. 253
Causer, Louise 338, 339
Cavasini, Carlos E. 697
Ceballos, Leonardo A. 394
Celermajer, David 486
Centeno, Ruth 884
Cernetich-Ott, Amy 802
Cerqueira, Gustavo 286
Cersovsky, Steven 1008
Certain, Laura K. 827, 828
Cespedes, Manuel 1046
Cetina-Trejo, Rosa C. 465
Cevallos, William 328
Chagas Júnior, Adenizar 98
Chahal, Jasdave 1073
Chai, Jong-Yil 567, 608, 840
Chaisri, Urai 604
Chaki, Prosper 41, 227, 845, 848
Chakravarty, J. 378
Chalé-Balboa, Wilberth G. 151, 152
Chambers, Eric W. 890
Champagne, Donald E. 393, 642,
947
Chan, Adeline S. T. 483
Chan, Joanne 995
Chan, Teik-Chye 434
Chan Thap, Lon 934
Chanama, Sumalee 107
Chancafe, Jorge A. 738, 1046
Chand, Gyan 183
Chanda, Pascalina 87, 355, 539,
543, 569, 674
Chandra, Prafulla K. 247
Chandrasekar, P. H. 719
Chandre, Fabrice 230
Chang, Gwong-Jen. J. 127
Chang, Moh Seng 26, 350
Chang, Wonsuk 653
Chantha, Ngan 28, 764, 897
Chao, Chien-Chung 434, 436
Chapilliquen, Fernando 884, 898
Author Index
Chareonviriyaphap, Theeraphap 586
Charlebois, Edwin D. 705, 706
Charles, Marie 708
Charriere, Fabien 1070
Charron, Brigitte 716, 717
Charurojpakorn, Chulaluck 515
Chattopadhyay, Suchismita 434
Chauhan, Chitra 874
Chauhan, Kamalesh R. 63
Chauhan, Virander S. 222, 566
Chaurasia, R. G. 182
Chaves, Luis F. 999
Checchi, Francesco 974
Checkley, Anna M. 356
Chelimo, Kiprotich 303, 556
Chen, Chien-Shien 921
Chen, Huiyuan 3
Chen, Honggen 290
Chen, Hua-Wei 436, 1066
Chen, Jun Hu 840
Chen, Jessica 959
Chen, Li-Kuang 127
Chen, Lan 345
Chen, Nanhua 187, 970
Chen, Ping 48
Chen, Wei-June 126
Chenet, Stella M. 203, 525
Cheng, Pei L. 631
Cheng, Qin 187, 563, 829, 970
Cherry, Sara 990
Cheun, Hyeng-Il 267
Chiang, Jannifer O. 123, 131
Childs, James 256
Chille, Masunga M. 842
Chimpeni, Phillips 1003
Chimutete, Mutale 355
Ching, Wei-Mei 434, 436, 1066
Chiodini, Peter L. 356
Chiou, Shyan-Song 127
Chipeta, James 355
Chirwa, Brian 841
Chisenhall, Daniel M. 470
Chishimba, Sandra 229, 938
Chitnis, Chetan E. 191, 306
Chitnis, Nakul 671
Chizema, Elizabeth K. 539
Cho, Pyo-Yeon 267
Cho, Pyo Yun 284
Cho, Shin-Hyeong 538
Chokephaibulkit, Kulkanya 2
Chong, Curtis R. 961
Chotivanich, Kesinee 515
Chotmongkol, Verajit 428
Chou, Tom 205
Chouaibou, Mouhamadou S. 865
Chowdhurry, Fahima 18
Chowdhury, Imtiaz A. 281
Chretien, Jean-Paul 104, 415, 438,
989
Christensen, Bruce M. 953
Christianson, Diane 1045
Chu, Yong-Kyu 923, 929
Chuang, Ching-Kai 126
Chuang, Ilin 11, 304, 581
Chuang, Ting-Wu 599
Chukwuocha, Uchechukwu M. 100,
413, 420
Chung, Dong Hoon 923
Chuquiyauri, Raul 541
Churcher, Thomas S. 385, 773
Chuxnum, Teerasak 911
Chwaya, Hababu 180
CIETNicaragua Dengue Group 645
Cislo, Paul 1060
Cisneros, Alejandro 106
Cissé, Guéladio 729
Claborn, David 583
Claps, Guillermo L. 398
Clardy, Jon 652, 821, 824
Clark, Eva 727
Clark, Gary G. 65
Clark, Kathryn 102
Clark, Tamara D. 675
Clegg, J.B. 207
Clem, Rollie J. 231, 279
Clements, David 305
Clennon, Julie 896
Coberly, Jacqueline 104
Coetzee, Maureen 591
Cogswell, Frank B. 509, 639
Cohen, Joe 8, 9, 10, 44, 218, 572,
578
Cohen, Justin M. 999
Colborn, J. M. 856
Colborn, James M. 913
Cole, Dana 59
Cole-Tobian, Jennifer 159
Colebunders, Robert 937
Coleman, Morton 1045
Coleman, Russell E. 185, 401, 444,
483
Coler, Rhea N. 141
Colley, Daniel G. 307, 310, 664
Collin, Nicolas 391, 981
Collins, Matthew H. 1072
Collins, William E. 509
Coloma, Josefina 86, 645
Colon, Candimar 754
Comer, James A. 281, 955
Comte, Eric 722, 974
Conn, Jan E. 249, 882
Connor, Elizabeth B. 428
Connors, Nicholas 530, 1053
Conroy, Andrea 799
Conway, David 197, 210, 302, 696,
812
Cook, Joseph 129
Cook, Joseph A. 901, 958
Cook, Peter E. 979
Cooper, Margarethe 266
Cooper, Roland 1067
Copeland, Curtis C. 751
Coppage, Myra 3
Coppens, Isabelle 647
Coppi, Alida 505
Corbel, Vincent 230
Cordoba, Liliana 249
Cordova-Benzaquen, Eleazar 627,
786
Cornejo del Carpio, Juan G. 627,
786
Corran, Patrick 302, 696
Corre, Sandra 214, 831
Correa, Margarita M. 249
Correa-Oliveira, Rodrigo 291
Correnti, Jason M. 1010
Cortinas, Roberto 1060
Cosio, Gabriela 632
Costa, Carlos 391
Costantini, Carlo 1027, 1035
Coudeville, Laurent 349
Coulibaly, Aliou 508, 856
Coulibaly, Cheick 242
Coulibaly, Drissa 14
Coulibaly, Karim 409
Coulibaly, Mamadi 186, 259
Coulibaly, Michel E. 952
Coulibaly, Yaya 952
Courtenay, Orin 792
Coutinho, Bruna P. 745, 752, 753
Coutinho-Abreu, Iliano V. 64, 397
Cowman, Alan F. 300, 550
Cox, Jonathan T. 590
Crabtree, Mary B. 1
Craft, Noah 150, 631
Craig, Philip S. 71
Creek, Tracy 16, 17
Crespo Ortiz, Maria del Pilar 654
Crevat, Denis 443, 454
Crill, Wayne D. 127
Crockett, Maryanne 920
Cronstein, Bruce N. 311
Cropp, Bruce 460
Crosby, Seth D. 362, 779
Crow, Emily T. 309
Crowley, Michael R. 847
Crozier, Sarah 812
Cruz, Ana C. R. 123, 131
Cruz, Karyn 884
Cubillas, Luis 884
Cui, Liwang 545
Cummings, Richard D. 334
Curatola, Antonino G. 680
Curns, Aaron 439
Curtis, Kurt C. 777
Curwen, Rachel 296
Custers, Jerome H. 44
Cutler, Stephen J. 639
Cutrera, Ana Paula 67
Cuzin-Ouattara, Nadine 846
216
Cysticercosis Working Group in Peru
30, 31, 371
Czesny, Beata 518
Czokajlo, Darek 68, 402, 585, 889
D
D’Acremont, Valerie 337
D’Alessandro, Umberto 206, 833,
937, 1005
D’Angelo, John 1057
DÁrcádia, Rosane R. 697
D’Ombrain, Marthe C. 301
da Fonseca, Flavio Guimaraes 991
da Nóbrega, Aglaêr A. 793
da Silva, Alexandre J. 810
da Silva, Eliana V. P. 123, 131, 755
da Silva, Érika V. S.. 137
da Silva-Nunes, Mônica 697
Da’Dara, Akram A. 1051
Dabiré, Kounbobr R. N. 241
Dabo, Abdoulaye 324
Dabod, Elijah 159
Dada-Adegbola, Hannah O. 179,
495
Dadzie, Samuel 597
Dahlbäck, Madeleine 49
Dai, Bui 94
Daily, Johanna P. 162, 368, 369,
489, 734, 935
Dale, James 382, 917
Dalvi, Rahul 630
Daly, Thomas M. 802
Dama, Souleymane 421, 712, 835
Damon, Inger K. 614, 991
Daniels, Rachel 204
Danko, Janine 115
Dantur Juri, María J. 398
Dao, Adama 588, 1022, 1057
Dao, Hoang Thi Nhu 456
Dao, M.T. 207
Dao, Nguyen V. H. 94
Daou, Modibo 324
Dara, Antoine 712
Dardick, Kenneth 1045
DaRe, Jeana T. 181
Das, Manoj K. 528, 877
Das, Pradeep 85, 624
Das, Suchismita 978
Dasch, Gregory A. 1066
Dasgupta, Tina 823
Dash, Aditya P. 182, 183, 194, 202,
341, 528, 535
Dash, A P. 1055
Dash, Paban K. 617
Daszak, Peter 467, 954, 956, 995
Dave, Kirti 483
Dave, Sonia 483
Davenport, Gregory 20, 200, 321,
Author Index
353, 548, 549, 694, 707, 1056
David, Makindi 809
David, Ryan 405
Davies, Stephen 293, 295, 297,
309, 311
Davila, Santiago 400
Davis, A. P. 314
Davis, Derek 187
Davis, Larry 663
Davis, Margarett 16, 17
Davis, Timothy M. E. 181, 1007
Davis-Rivers, Andrea N. 440
Dawson, Harry 983
Day, Karen P. 649, 1059
Day, Tim A. 953
Dayal, A 90
de Bosch, Norma 24
de Jesus, Amelia R. 283
de Koning, Harry 516
de la Garza, M. 278
De La Vega, Patricia 217
de Luise, Cynthia 517
de Monbrison, Frédérique 968, 973
de Oliveira, Ana 363
De Paula, Sérgio O. 757
de Vlas, Sake J. 359
De-Cozar, Cristina 171
Dea-Ayuela, Maria A. 273
Deans, Anne-Marie 702, 1058
Debatis, Michelle 629
Debrah, Alexander Y. 388, 389
deBruyn, Becky 874
DeCaprio, David 162
DeGaetano, Arthur 265
Deininger, Susanne 197
DeJong, Randall 1037
Dejsirilert, Surang 915
Del Cid, Jaime 787
del Rosal, Marina 826
Delgado, Richard C. 206
della Torre, Alessandra 871
Delphine, Aldebert 553
Delroux, Karine 646
Dembele, Benoit 952
Dembele, Demba 421, 492, 835,
1057
Demir, Samiye 791
Demoitié, Marie-Ange 8, 10, 12,
44, 572
Deng, Haiyan 514, 639
Denis de Senneville, Laure 238
Denlinger, David L. 233
Dennull, Richard A. 820
Dent, Arlene E. 556
DeOlivera, Ana 781
DeRocher, Amy 647
Dery, M. A. 416
Desai, Megnha 535
Desai, Manish A. 895
Desai, M. R. 341
Desai, Prashant V. 862
Descloux, Elodie 449
DeSilva, Erandi 1073
Desruisseaux, Mahalia S. 805
Desta, A. 718
Dev, Vas 877
Devi, Sangeeta 566
Devine, Gregor J. 623
Di Paolo, Adriana 89
Dia, Ibrahima 466
Diabate, Abdoulaye 588, 1022
Diakite, Souleymane 384
Diallo, Abdallah 952
Diallo, Boubacar 508
Diallo, Dapa A. 14, 1058
Diallo, Mawlouth 466
Diallo, Souleymane 326
Diarra, Issa 324
Dias, Sajani 191
Diassiti, Angelina 920
Diawara, Aissatou 133
Díaz, André 30
Diaz, A. 957
Diaz, Francisco J. 446
DiBlasi, Michael 891
Dickason, John 1045
Dicko, Alassane 13, 14, 421, 492,
651
Dicko, Adama 409
Dicko, A 710
Dicko, Yaya 717
Diemert, David 13
Dieng Sarr, Moussa 935
Diet, Tran V. 452
Dieye, Alioune 214
Diffenbaugh, Noah S. 657
Diggs, Carter 11, 48, 304, 581
DiGiacomo, Giuseppina 158
Dillon, Gary 296
Dimaano, Efren 119
Dimech, George S. 997
Dimopoulos, George 40, 640, 943,
978
Dinguirard, Nathalie 1030
Dinkel, Anke 372
Diouf, Ababacar 13, 48, 425
Diraviyam, Karthikeyan 1002
Dituvanga, Ndinga D. 476
Diuk-Wasser, Maria A. 256, 602,
1060
Djikeng, Appolinaire 286
Djimde, Abdoulaye A. 14, 421, 492,
635, 712, 835, 1057
Djogbenou, Luc 230
Djouaka, Rousseau F. 621
Do, Q.A. 207
Dobaño, Carlota 306
Dobbelaere, Dirk A. 1076
Dobler, Gerhard 463, 904
Dobson, Andrew P. 956
Dobson, Stephen L. 437
Dodean, Rosie 822
Dodoo, Daniel 192
Doerner, Frank 722
Dohn, Anita L. 138
Dohn, Michael N. 138
Dokomajilar, Christian 340, 423,
706
Dolo, Husseini 952
Dolo, Ibrahim 508
Dominguez-Galera, Marco 893
Doms, Robert W. 612, 990
Donelson, John E. 144
Dong, Carolyn 369, 489
Dong, John 345
Dongier, Pierre 383
Dongus, Stefan 261, 848
Donnelly, Christl 349
Donnelly, Martin 865
Donner, Marie-Noelle 44
Donovan, Michael J. 670
Doolan, Denise L. 11, 48, 304, 581
Doorley, Sara 408
Dorabawila, Nelum 334
Dorfman, Jeffrey R. 580
Dorji, Tandin 113
Dorsey, Grant 93, 340, 675, 705,
706, 1005
Dosoo, David K. 726
Dotson, Ellen M. 67, 394
Doty, Jeffrey B. 932
Douglas, Jessica 785
Doumbia, Mama N. 326, 740
Doumbia, Seydou 409, 510, 710,
868
Doumbo, Ogobara K. 13, 14, 324,
421, 492, 635, 712, 835, 1057
Dow, Geoffrey S. 357, 502
Dow, Steven 993
Dowell, Scott F. 330, 331, 908
Dozie, Ikechi N. S. 100
Dozie, Ikechukwu N. S. 413, 420
Drake, Lesley J. 133
Drescher, Axel W. 261
Duah, Nancy O. 302
Dubey, Mohan L. 521
Dubois, Marie-Claude 8, 10, 44,
572
Dubois, Patrice M. 44
Dubovsky, Filip 8, 9, 572
Duc, Hoang M. 644
Ducatez, Mariette M.F. 682
Duffull, Steve 486
Duffy, Patrick E. 322, 580, 1054
Duggal, Priya 964
Dujardin, Bruno 481
Dujardin, Jean-Pierre 394
Duke, Brian O. L. 776
Dumas, Rafaele 344
Dumontiel, Eric 151, 152, 787
217
Duncan, Elizabeth H. 12, 161, 215,
220
Dung, Nguyen Minh 452, 1042
Dunham, Eleca J. 616, 688
Dunn, John 260
Dunstan, SJ 207
Duong, Socheat 26
Duong, Veasna 26
Dupressoir, Anne 466, 689
Dupuis, Alan P. 467
Duraisingh, Manoj T. 163, 1021
Durand, Patrick 38
Durbin, Anna P. 213, 347
Duriseti, Sai 488
Durvasula, Ravi 624
Dusfour, Isabelle C. 60, 583
Dushoff, Jonathan 956
Dutra, Walderez O. 312, 316
Dutta, Sheetij 303
Dvorak, James A. 487
Dzinjalamala, Fraction K. 530, 834,
969
E
Eampokalap, Boonchuay 327, 329
Easterbrook, Judith 277
Ebel, Gregory D. 129, 661
Ebringer, Andrew 187
Echevarria, Leonor 663
Echeverry, Diego 837
Edelman, Robert 216
Eder, Gerald 122
Edgil, Dianna M. 768
Edoh, Dominic 192
Edstein, Michael D. 94, 173, 174
Edwards, Camille 186, 259
Egah, Daniel 692
Egger, Joseph R. 447
Egyir, Beverly 211
Ehrenkaufer, Gretchen M. 1048
Eigege, Abel 422
Eisele, Thomas P. 177, 184, 560
Eisen, Lars 58, 888, 892, 893
Eisen, Rebecca J. 58
Eisenberg, Joseph N. S. 51, 52, 328,
895
Eitoku, Chiho 575
Ejigsemahu, Yeshewamebrat 700,
849
Ekanayake, Sajeewane 444
Ekgatat, Monaya 911
Ekloh, William 198
Eksi, Saliha 518
El Setouhy, Maged 360, 361
El-Aassar, E M. 79
El-Hossary, Shaaban 61, 64, 397
El-Kamary, Samer 731
El-Mohamady, Hanan I. 905
Author Index
El-Sayed, Najib 286, 1033, 1050
Elamin, Mohamed 372
Eldridge, Bruce F. 584
Elie, Cheryl 384
Elizondo, Douglas 25
Elizondo-Quiroja, Darwin 892, 893
Elliman, Jennifer 771
Elling, Berty F. 529, 537
Ellis, Ruth D. 213
Ellis, William 650
Elmendorf, Heidi G. 967
Elnahas, Ayman 372
Elnaiem, Dia-Eldin 69, 391, 396,
981, 1039, 1052
Emerson, Ginny 991
Emerson, Paul 700, 849
Endeshaw, Molla 1002
Endeshaw, Tekola 700, 849
Endy, Timothy 763, 767
Eng, Jeffrey L. K. 386
Enright, Bill 48
Epstein, Judith E. 11, 43, 216
Epstein, Jonathan H. 954, 956
Erdman, Laura 632
Eren, Hasan 788
Erexson, Cindy 1017
Erickson, Sara M. 953
Ernst, Kacey C. 814, 853
Ertabaklar, Hatice 148, 788, 791
Ertug, Sema 148, 788
Escalante, Ananias A. 203, 860,
971, 972
Escobedo, K. 930
Escombe, A. Roderick 680
Escueta, Aleyla S. 564
Esmat, Gamal 731
Espinosa, Avelina 965
Espinosa, Benjamin J. 747, 750, 928
Espinoza, Yrma 381
Espinoza Zegarra, Nereyda 747
Esposito, Joseph 274
Essamia, Fabian 651
Essbauer, Sandra 463
Essel, Kofi 899
Esteves, Gabriela 98
Etang, Josiane 865
Etheridge, Ronald 1074
Etouna, Joachim 1035
Ettestad, Paul 663
Ettling, Betty F. 95
Evans, Carlton A. 680
Evans, James E. 649
Evans, Sandra 435
Eversole, Rob R. 387, 982
Ewing, Dan 345
Eyamba, Albert 770
Eyangoh, Sarah 722
Eza, Dominique 930
Ezedinachi, Emmanuel 651
F
Faccioli, Lúcia H. F.. 137
Fagbenro-Beyioku, Adetayo F. 523
Fairfax, Keke C. 628
Fairlie, David P. 165
Falade, Catherine O. 179, 404
Falade, Cathrine O. 495, 547
Falta, Michael T. 316
Fantappie, Marcelo R. 1032
Farah, Omar 619
Farfan-Ale, José A. 465, 893
Farias, Kleber J. S. 931
Farid, Hoda A. 360, 361
Farnon, Eileen C. 1043
Farrar, Jeremy 22
Farrar, J.J. 207
Farrar, Jeremy 452
Faruque, Abu S. G. 18
Fatoumata, Dicko-Traore 712
Faucette, Laurence 1017
Faulde, Michael 463
Favata, Mike 415
Fawaz, Emad 64, 397
Fawole, Funmi 99
Faye, Babacar 717
Faye, Ousmane 409, 466, 710
Feagin, Jean E. 647
Febles, Taynet T. 77
Fegan, Gregory 554
Fehintola, Fatai A. 88
Feikin, Daniel 15, 619
Feng, Carl G. 667
Feng, Gaoqian 808
Feng, Zheng 290
Fenton, Michael E. 76
Ferdig, Michael T. 160, 854, 939
Ferguson, David J. 604
Ferguson, Heather 593
Fernandes, Liselle 693
Fernández, Alejandra 512, 513
Fernandez, Miguel 19, 683
Fernandez, Roberto 898
Fernandez-Salas, Ildefonso 626, 893
Fernández-Velasco, D. Alejandro
271
Ferreira, Marcelo U. 697
Ferrell, Robert 200, 321, 548, 1056
Ferrer, Santiago 512
Ferrer-Rodriguez, Ivan 836
Ferro, Cristina 797
Fidock, David A. 505, 940
Field, Hume E. 954, 956
Figueira, Claudio P. 98
Fikrig, Erol 590, 646
Filice, Carlo 72, 73, 374
Filipe, João A. 773
Filler, Scott 704
Fillinger, Ulrike 41, 41, 227, 261,
845, 848, 851
Filone, Claire Marie 990
Fimmers, Rolf 389
Findlow, Helen 384
Finney, Olivia 197, 696
Firbas, Christa 687
Fischer, Kerstin 362, 785
Fischer, Marc 1041
Fischer, Peter U. 362, 785, 777, 985
Fish, Durland 256, 602, 1060
Fisher, Cynthia 329
Fisk, Tamara 331
Fisk, Tamara L. 908
Fitzpatrick, Nicole 110
Flannery, Brenden 21
Fleischer, Bernhard 949
Flores, Diana 6, 117
Flores-Flores, Luis F. 465
Flores-Mendoza, Carmen 884
Flores-Suarez, Adriana E. 626
Florey, Lia S. 699
Florin, David 623, 866, 884
Fofana, Bakary 421, 492, 835, 1057
Fogako, Josephine 559
Folarin, Onikepe A. 88, 524, 527
Foley, Desmond H. 881
Fonseca, Benedito A. L. 120, 450,
757, 761, 931
Fonseca, Dina 875
Fontenille, Didier 38, 238, 1027,
1035
Fontenot, Andrew P. 316
Fontes, Cor J. Fernandes. 568
Foppa, Ivo M. 600, 1045, 1062
Forbes, Wayne M. -. 132
Ford, Karen 692
Ford, Robert 692
Formenty, Pierre 989
Formica, Alessandra 122
Fornadel, Christen M. 250, 591,
879, 896
Fornasini, Gianfranco 1009
Forrat, Remi 344
Forsyth, Simon J. 290
Foster, Woodbridge A. 1026
Foster, Stanley O. 175
Fottrell, E 718
Fouda, Genevieve Giny 425
Fowkes, Freya J. I. 1059
Fowler, Elizabeth V. 563
Fox, LeAnne M. 678
Fox, Matthew P. 678
Foxman, Betsy 328
Frace, Mike 991
Fraga, Lucia A. O. 291, 293, 311
Francis, Filbert 842
Francis, Susan 580
Franco, Jose R. 476
Franco-Paredes, Carlos 796, 1000
218
Franz, Alexander 441, 455, 1038
Fraser, Malcolm J. 1010
Freed, Brian 316
Freitas, Daniel 997
Frempong, Margaret T. 596
Freundlich, Joel S. 505
Fried, Michal 322, 580, 1054
Friedman, Jennifer 70
Frolov, Ilya V. 658
Frosch, Matthias 375
Fryauff, David 61, 597
Fujita, Wendy 998
Fukuda, Mark 218, 430, 565, 636,
832, 863, 934
Fuller, Douglas O. 894
Furman, Richard R. 1045
Fusaï, Thierry 238, 818
Fusch, Christoph 803
G
Gad, Adel M. 360, 361, 1040
Gaither, Amber D. 834
Galagan, James E. 162, 368, 579
Galinski, Mary R. 806
Galler, Ricardo 98
Gallup, Jack 315
Gálvez-Buccollini Abanto, Juan A.
723
Gambhir, Manoj 909
Gamboa, Dionicia 206
Gamboa-Leon, Rubí 787
Gamo, Francisco-Javier 171
Gandhi, Deepika 90
Ganesan, Suresh 858, 859
Ganeshan, Harini 304
Ganley-Leal, Lisa M. 664
Gao, Qi 970
Gaona, Heather W. 656, 817
Garcez, Lourdes 792
Garcia, Hector 31, 33
Garcia, Hector H. 29, 30, 35, 371
Garcia, Héctor H. 903
Garcia Bustos, José-Francisco 171,
505
Garcia-Miss, Maria 151
García-Pérez, Adolfo 512
Garcia-Rejon, Julian 465, 465, 893
Gardella, Catalina E. 106
Gardiner, Donald L. 165
Gardner-Santana, Lynne C. 959
Gardon, Jacques 776
Gargallo, Domingo 511, 512, 513,
826
Garges, Eric 1008
Garnett, Geoff 349
Garrido, Fàtima 28, 764
Garrison, Laurel E. 59
Garuti, Helena 512, 513
Author Index
Garver, Lindsey S. 943
Gasasira, Anne F. 705, 706
Gascot, Edalish 836
Gatakaa, Hellen 554
Gates, Casey 368
Gatewood, Anne 1060
Gatlin, Michael R. 307
Gatraud, Paul 505
Gatti, Simona 72
Gatton, Michelle L. 563, 829, 970
Gaur, Upasna 630
Gause, William 983
Gavidia, Cesar M. 29, 371
Gay, Cyril G. 412
Gaydos, Joel C. 438
Gaye, Oumar 634, 717, 1004
Gazzinelli, Giovanni 291
Gba, Bernadin 496
Gbotosho, Grace O. 88, 524, 527
Gbotosho, Sola 404
Gebre, Teshome 700, 849
Gebregeorgis, Elizabeth M. 573
Geerken, Roland 1060
Gehrke, Andrew 1073
Geissbühler, Yvonne 41, 227, 845,
848
Gelfand, Jeffrey A. 1045
Genco, Francesca 72
Genet, Asrat 700
Genov, Jordan 373
Genton, Blaise 337, 973
Gerena, Lucia 170, 415, 503, 656,
817
Gerrets, Rene P. 529
Getachew, A. 718
Getis, Arthur 264
Getrtraud, Regula 97
Gettayacamin, Monthip 218, 503
Getz, Tony 580
Gewurz, Ben 1045
Ghabour, Sylvia 905
Gharib, Sina A. 1018
Ghedin, Elodie 1068
Ghosh, Kashinath 318, 480, 624
Ghosh, Mousumi 142
Gibble, Joan 196
Gibbons, Peter L. 501
Gibbons, Robert V. 2, 113, 429,
763, 765, 767, 760
Gibson, Gabriella 1023
Gibson-Corley, Katherine N. 143
Gicheru, Nimmo 554
Gil, Ana I. 903
Gil, Pedro 837
Gill, Jeff 584
Gilman, Robert H. 29, 30, 31, 33,
266, 541, 627, 680, 749, 786, 866
Gimite, Dereje D. 149
Gimnig, John E. 587, 595, 1036
Gingrich, John B. 875
Ginsberg, Michele 469
Giraudoux, Patrick 71
Girault, Lang 466, 689
Giron, Luis Israel 787
Girouard, Autumn S. 961
Gitau, Evelyn N. 485
Gitawati, Retno 486
Githure, John I. 248, 1026
Gittleman, John 995
Glanfield, Amber 308
Glass, Gregory E. 108, 277, 896,
959
Glass, Jonathan 104
Glass, Roger I. 439
Gnémé, Awa 846
Go, Rodrick 507
Goade, Diane 129, 663
Gobert, Geoffrey N. 287, 289, 1010
Goethert, Heidi K. 901, 1062, 1063
Goetz, Sue 994
Goetz, Scott J. 467
Goff, Jay 992
Goff, Tami 196
Goh, Li Ean 651
Goka, Bamela Q. 195, 198
Goldin, Robert 452
Golemanov, Branimir 373
Gollob, Kenneth J. 312, 316
Gomes, Regis B. 69, 391, 396, 981,
1039, 1052
Gomes-Ruiz, Alessandra C. 120,
450
Gomez, Andres 467
Gomez, Rosa 852
Gomez, Tangni 25
Gómez, Vanesa 512, 513
Gomez-Benavides, Jorge 957
Gomez-Carro, Salvador 893
Gomez-de-las-Heras, Federico 171
Gomez-Escobar, Natalia 197, 210,
812
Gomez-Machorro, Consuelo 874
Gonçalves, Lígia A. 1019
Goncalvez, Ana P. 457
Gong, Hong Fei 265, 592
Góngora, Rafael 797
Gonzaga, Victor E. 903
Gonzales, Armando E. 29, 30, 31,
35
Gonzales, Joseph M. 160, 939
Gonzalez, Alcides 110
González, Bárbara 836
González, Gloriene 836
Gonzalez, Jesus 332
Gonzalez, Rodrigo 1022
Gonzalez-Cerdas, Rodrigo 876
Gonzalez-Ceron, Lilia 852
Gonzalvez, Guillermo 30, 31
Goodin, Douglas 929
Goodman, Catherine 499
Goodrich, Raymond P. 606
Gopi, P G. 666
Gopinath, Shankar P. 32
Gordon, Aubree 25, 684
Gordon, Scott 332
Gore Saravia, Nancy 797
Gorman, Ann Marie 461
Gose, Severin 49
Goshu, Samrawit 518
Gosi, Panita 863
Goto, Yasuyuki 141
Gottstein, Bruno 97, 377, 963
Gotuzzo, Eduardo 986
Gouagna, Louis C. 1026
Goudsmit, Jaap 44
Gould, Fred 946
Govella, Nicodem 41, 227, 845,
848
Govil, Dhwani 274, 991
Gowda, D. Channe 1020
Gowda, Kalpana 48
Graczyk, Thaddeus K. 961, 962
Graf, Paul C. F. 438, 1065
Graham, Sean 926
Grais, Rebecca 722
Granda, Bertha 1046
Grande, Tanilu 206
Grandesso, Francesco 725
Granger, Don 486
Grant, Alan J. 244
Grant, Dorsey 423
Gratias, Kambau M. Deo. 476
Graves, Patricia 700, 849
Graves-Abe, Katie 708
Graviss, Edward A. 32
Gray, Darren J. 290
Gray, Ronald L. 96
Green, Sharone 453, 765, 767
Greenaway, Christina 383
Greenbaum, Doron 491
Greenberg, Robert M. 288, 1031
Greene, Jennifer 695
Greenhouse, Bryan 675
Greger, Stephanie 631
Gregory, Robin 187
Greif, Gisela 963
Grieco, John P. 63, 60, 583
Griffing, Sean M. 971, 972
Griffith, Matthew 714, 715
Grigorov, Nikola 373
Grijalva, Mario J. 400
Grimberg, Brian T. 809
Grinstein, Sergio 632
Grisolia, Antonella 72, 73, 374
Gross, Tiffany 643
Grube, Marcus 803
Gruener, Beate 375
Gu, Weidong 246, 248, 252
Guerin, Philippe J. 974
219
Guerrant, Richard L. 440, 745, 748,
751, 752, 753, 1047
Guerena-Burgueno, Fernando 618
Guiguemdé, Robert Tinga 651, 790,
833
Guillard, Bertrand 81
Guimarães, Luiz H. S. 312, 380
Guindo, Ando B. 14
Guindo, Boubacar 868
Gulinello, Maria 805
Gunes, Koray 148
Gunning, Robin 433
Gunsaru, Bornface 655
Guo, Jiagang 290
Gupta, Lalita 39, 243, 941, 1037
Gupta, Nimesh 617
Gupta, Raj K. 63
Gupta, Shaili 1045
Gupta, Vineet 410, 742
Gurarie, David E. 540
Gurary, Alexandra 23
Gurley, Emily 281, 933, 955, 1041
Gürtler, Ricardo E. 67, 392, 394
Guthmann, Jean-Paul 974, 1005
Gutiérrez, Lina A. 249
Gutman, Julie R. 422
Gutteridge, Clare E. 819
Guyer, Craig 926
Gwadz, Bob 1022
Gyang, Fredrick N. 195
Gyapong, John O. 386
H
Ha, Tran Thi Ngoc 456
Haake, David 98
Habbema, J D. F. 359, 676
Habomugisha, Peace 770
Hadi, Azam 514
Hadisoemarto, Panji F. 766
Haertle, Sonja 10
Haesler, Barbara 97
Hafy, Zen 766
Haidara, Fadima C. 384
Hailemariam, Afework T. 849, 891
Hall, Eric R. 750
Hall, Martin J. R. 79
Halpin, Kim 954
Halstead, Scott B. 767
Halvorsen, Jake G. 1040
Hamainza, Busiku 355, 539, 569
Hamarsheh, Omar Y. M. 864
Hamel, Mary 338, 339, 351, 546,
1036
Hamer, Davidson H. 535
Hammad, Ragaa E. 361
Hammond, Samantha 86
Han, Eun Taek 840
Hanafi, Hanafi A. 61, 64, 397, 401
Author Index
Handunnetti, Shiroma M. 191
Hanelt, Ben 299, 1029
Hannah, Michele F. 555
Hanshoaworakul, Wanna 960
Hanson, Christopher 124
Hanson, Kevin 102
Hanssen, Eric 654
Happi, Christian T. 88, 404, 524,
527
Haque, Rashidul 636, 964, 966
Haralambou, George 77
Harker, Brent 874
Harn, Donald A. 1051
Harrell, Robert A. 240
Harrington, Laura C. 66, 265, 592
Harris, Eva 6, 25, 86, 110, 116,
117, 684
Harris, Jason B. 18
Harris, Juliana V. 189
Harrison, Lisa 628
Hartl, Daniel L. 368
Hartman, Barry 1045
Hartmann, Chris 992
Hartmann, Katherine 703
Hartmann, Wiebke 949
Hartwig, Carmony 1067
Harty, Ronald N. 611
Hashem, Mohamed 731
Hashimoto, Caryn 305
Haskell, Jacquelyn N. 631
Hassan, Hassan K. 880, 926
Hassan Sharifah, Syed 954
Hassanali, Ahmed 1026
Hastings, Ian M. 936
Hatabu, Toshimitsu 564
Hatch, Douglas 997
Hau, Tran P. 644
Hauer, M. C. 878
Havlir, Diane 705, 706
Hawela, Moonga 569
Hawkes, Clifton 379
Hawkes, Michael T. 920
Hawkins, Vivian N. 533
Hawley, William A. 736, 736
Hayakawa, Toshiyuki 564
Hayes, Curtis 115, 346, 444
Hayes, Daniel J. 497
Hayes, Edward B. 473
Haynes, J. D. 1015
Hazir, Tabish 678
Heady, Tiffany N. 656, 817
Hehl, Adrian 1076
Heiman, Donald F. 1045
Heintz, John 181
Heinz, Franz X. 687
Heinz, Michael 362
Helmers, Andrew 164
Helmy, Hanan 360, 361
Hemingway, Janet 621
Hemphill, Andrew 75, 376, 605,
963
Henipavirus Ecology Research Group
(HERG) 954, 956
Henn, Matthew 25
Henry, Maud 818
Hensley, Lisa 992
Henson, Mike 473
Heppner, D. Gray 12, 44, 218, 578
Hermann, Pascal 1076
Hernandez, Carlos 645
Hernandez, Jean N. 727, 850
Hernandez, Roger 381
Hernández-Campos, Alicia 269,
270, 271, 273
Hernández-Campos, Maria A. 272
Hernández-Luis, Francisco 269, 270,
272, 273
Herrera, Flor 867
Herrera, Socrates 43
Herrera Camino, Andres 747
Herreros, Esperanza 826
Hess, Lindsey 653
Hesse, September 804
Hibberd, Patricia L. 609
Hickey, Patrick W. 445
Hidalgo-Martinez, Ana C. 465
Higazi, Tarig B. 363
Higgs, Stephen 613, 658, 730
Hightower, Allen 546, 587, 619
Higuita, Edwin A. 446
Hill, David 1045
Hillesland, Heidi 624
Himley, Stephen 55
Hinckley, Alison F. 473
Hinnebusch, B. J. 912
Hinrichs, Dave 822
Hira, Parsotam R. 79
Hirsch, Damien 517
Hisamori, Daisuke 484
Hiser, Ashley F. 56
Hittner, James B. 353, 694, 707,
1056
Ho, Walter 305
Hoang, Long T. 4
Hoang Le, Nguyen 644
Hocart, Simon J. 639
Hochbein, Roselyn 1043
Hodgson, Abraham 103
Hodson, Cheryl 655
Hoel, David 61, 64, 397, 401
Hoerauf, Achim 388, 389, 785
Hoffman, Marshall M. 819
Hoffman, R. L. 399
Hoffman, Stephen L. 216
Hoffmann, Erika H. E. 697
Hoke, Charles H. 102
Holder, Anthony 193
Hole, D G. 594
Hollingdale, Michael R. 158
Holloway, Brian 274
Holman, David 345
Holmes, Edward C. 616, 688
Holt, Deborah 433
Holt, Robert D. 959
Homira, Nusrat 281, 955
Homma, Akira 98
Hong, Sung-Jong 284
Hope, Andrew 129
Hopkins, Heidi 93, 340, 343
Horton, Ashley A. 242, 1024
Hospenthal, Duane 714, 715
Hossain, Jahangir 1041
Hossain, M. J. 281, 933, 955
Hotez, Peter 987
Hottel, Hannah 125
Hou, Min 70
Houde, Nathan 368
Hougard, Jean-Marc 230
House, Brent L. 217
House, Susan 242
Howell, Katherine 550
Howgate, James 464
Hsiao, Chia-Hung Christine 144
Hsu, Bing-Mu 921
Huallpa, C. 957
Huaman, A. 930
Huaman, Moises 19
Huang, Claire Y. 1, 114, 471
Huang, Ling 71
Huang, Mingbo 804
Huang, Shuhui 573
Huang, Yeufang 779
Huayanay, Leandro 381
Hubbard, Alan 51, 52, 328
Hübner, Marc P. 948
Huddler, Donald P. 656, 817
Huddleston, Beth 260
Hudson, Thomas H. 502, 656, 817
Hue, Nguyen D. 94
Huertas, Mariela 837
Huggel, Katja 333
Huggins, John 992
Hughes, Dyfrig A. 1003
Hughes, Mark T. 932
Hugo, Leon E. 979
Hui, George 305
Hulit, James 146
Humbel, Bruno 1069
Hume, Jen 226, 876
Hunja, Carol W. 578
Hunsperger, Elizabeth 472, 756
Hunt, Richard H. 591
Hunter, Gabrielle C. 749
Huong, Vu Ti Que 443, 456
Hurtado, Northan 725
Hurwitz, Ivy 624
Husain, Sohail 628
220
Hussain, Waqar 678
Hussaini, Isa 753
Hutchinson, Rob 594
Hutson, Christina L. 614
Huy, Rekol 26
Hyatt, Alex 954
I
Iadarola, Michael J. 135
Iamsirithaworn, Sopon 960
Ibadova, Gulnara A. 744
Ibarguen, Dario 837
Ibrahim, Mohamed 887
Ide, Charles 982
Idowu, Dare O. 524
Ilboudo-Sanogo, Edith 846
Ilett, Kenneth F. 501, 638, 1007
Ilika, Amobi L. 620
Imade, Godwin 692
Imrie, Allison 23
Intapan, Pewpan M. 428
Irawati, Dyah 681
Irfan, Seema 679
Iriko, Hideyuki 574
Isaacson, J. 519
Isaacson, Jeffrey D. 172
Ishengoma, Deus 842
Isoe, Jun 235, 236, 975, 976
Ito, Akira 72, 375
Itoh, Sonoyo 72, 375
Ittiprasert, Wannaporn 1033, 1049,
1050
Iwagami, Moritoshi 564
Iwuagwu, Francis O. 420
Iya, Daniel 692
Iyiola, Yemisi 404
J
Jacob, Benjamin 248
Jacobs Jr., William R. 505
Jacobus, David P. 173, 174, 505
Jacobus, Laura R. 173, 174
Jacquemot, Catherine 195
Jacquerioz, Frederique A. 186, 259
Jadav, Suresh 384
Jafari, Seyed M. 919
Jaffe, Donald R. 517
Jago, Jeffrey D. 501, 638
Jain, S. K. 222
Jain, Vidhan 194, 1055
Jairungsri, Aroonroong 2
Jamaluddin, Abdul Aziz 954
Jambou, Ronan 831
James, Mark 787
Jarilla, Blanca 70
Author Index
Jarman, Richard G. 2, 113, 618,
760, 763, 765, 767
Jaron, Peter 15
Jarrett, Clayton O. 912
Jaworowski, Anthony 693
Jayakumar, Asha 670
Jayantasri, V. 666
Jeffery, Jason A. L. 644
Jei, Fei 142
Jennings, Cameron V. 1021
Jentes, Emily S. 186, 259
Jenwithisuk, Rachaneeporn 515
Jeronimo, Selma M. 313
Jerzak, Greta V. S. 661
Jiang, Daojun 777
Jiang, Ju 1065
Jiang, Lubin 488
Jiang, Lei 939
Jilma, Bernd 687
Jiménez, Elena 511
Jimenez, Juan 31
Jimenez, Victor 507
Jimenez, German 175
Jiménez-Díaz, Belén 512, 513
Jin, Lizhong 239
Jin, Ling 574
Jin, Xia 3, 457
Jin, Yamei 37
Jitpimolmard, Suthipun 428
Jiz, Mario 70, 335
Jobe, Ousman 319
Jochim, Ryan 391, 1039
Joel, Pradeep K. 1055
Johansson, Michael 108
John, Chandy C. 695, 814, 853
Johnson, Armead 425
Johnson, Barbara W. 128
Johnson, C. E. 278
Johnson, Dawn 177, 184
Johnson, Jacob D. 650, 656, 817,
820
Johnson, Jeff R. 370
Johnson, Karen 268
Johnson, Reed F. 611
Johnson, Stephanie T. 1044
Johnson, Wesley O. 584
Johnston, Dean 46
Johnston, Stephanie P. 810
Johnston-Gonzalez, Richard 886
Jones, Douglas 143
Jones, Douglas E. 142, 315
Jones, Franca 750
Jones, Jeffrey G. 411
Jones, Jeffrey L. 101, 134
Jones, Kate 995
Jones, LeeAnn 67
Jones, Lahna 650
Jones, Malcolm 308
Jones, Matthew J. 467
Jones, Tim F. 260
Jongsakul, Krisada 934
Jongwutiwes, Somchai 542, 545
Jonsson, Colleen 923, 929
Joos, Charlotte 214
Jorakate, Possawat 327, 329, 911,
915
Jordan, Stephen J. 847
Joshi, Durga M. 429
Joshi, Hema 202
Ju, Jung-Won 267
Juarez, Marisa 89
Juliano, Jonathan J. 811
Juma, Vera 676, 830
Juncansen, Camlia 697
Jung, Yoon-Jae 157
K
K’Ogal, Amos 707
Kaba, Stephen A. 45
Kabalo, Abel 355
Kabanywanyi, Abdunoor M. 633,
676, 830
Kabeya, Alain M. 476
Kabir, Mamun 966
Kabiru, Ephantus W. 1026
Kabyemela, Edward R. 322
Kachur, S. Patrick 21, 95, 342, 499,
529, 537, 633, 676, 830
Kaewpan, Anek 327, 915
Kafwani, Mzungu 153
Kagaayi, Joseph 96
Kahigwa, Elizeus 21
Kahn, Ashraful 18
Kahnberg, Pia 165
Kai, Oscar 1058
Kain, Kevin C. 164, 632, 799, 920,
1018
Kalanarooj, Siripen 763, 765
Kalanidhi, A. P. 114
Kalayanarooj, Siripen 453
Kale, Oladele 406, 407
Kalilani, Linda 519, 808, 1053
Kalinna, Bernd H. 1010
Kaltenböck, Astrid 122
Kalyango, Joan 93
Kam, Adele 682
Kamal, Michael 369
Kamal, Sherin A. 361
Kamanga, Aniset 896
Kambale, Wilson 340
Kamdem, Colince D. 1035
Kamgno, Joseph 776
Kamhawi, Shaden 64, 69, 395, 396,
397, 981, 1052
Kaminski, Robert 750
Kamugisha, Mathias L. 842
Kamya, Moses R. 93, 340, 675,
705, 706
Kanbara, Hiroji 789
Kande, Victor 481
Kane, Anne V. 609
Kaneko, Osamu 574
Kang, Mi-Ae 561
Kang, Young-A 538
Kang’a, Simon 850
Kango, Mabvuto 355
Kannady, Khadija 41, 227, 261,
845, 848, 851
Kano, Shigeyuki 208, 564
kanobana, Kirezi 33
Kaplan, Jenifer 277
Kaplan, Ray M. 988
Kappe, Stefan H. I. 319, 364
Kapre, Subash 384
Karagenc, Tülin 788
Karamagi, Charles 93
Karanja, Diana M. S. 307, 310, 336,
664
Karema, Corine 734
Karim, Coulibaly 710
Karim, Mohammad M. 609
Kariuki, Michael M. 490, 493, 798,
861
Kariuki, Simon 338, 339, 971
Kariuki, Tom 296
Karl, Stephan 809
Karnataki, Anuradha 647
Karnchaisri, Kriangkrai 542
Karunajeewa, Harin A. 181, 1007
Karyana, M 354, 544, 701
Kasper, Jacob M. 1013
Kastens, Will 358
Kasumba, Irene N. 873
Kasymbekova, Kalya 925
Katabarwa, Moses N. 770
Katebe, Cecelia 844
Katkowsky, Steven R. 464
Kaufusi, Pakieli H. 468
Kaur, Harparkash 499
Kauth, Christian W. 194
Kawai, Hiroyuki 55
Kawai, Vivian 786
Kawazu, Shin-ichiro 208
Kay, Brian H. 644, 979
Kayange, Noel 1003
Kaye, P. 1071
Kazura, James W. 358, 556, 695
Ke, Hangjun 859
Keating, Joseph 177, 184, 259, 560
Kebaier, Chahnaz 37, 156
Kebede, Asnakew 891
Keiser, Jennifer 376
Keita, Mahamadou M. 326, 382,
917
Keita, Mamadou M. 326, 508, 712,
740
Keita, Somita 409, 710
Kekitiinwa, Adeodata 705
221
Keller, Christopher 321, 549, 694,
1056
Keller, Thomas 692
Kelley, James 460
Kelly, Jane X. 655, 822
Kelly, Rosmarie 464
Kemisetti, Sumathi 902
Kenangalem, Enny 354, 486, 544,
701
Kendino, Gideon 187
Kengluecha, Ampornpan 515
Kennedy, Allison C. 355
Kent, Rebekah J. 250, 462, 879
Kerce, Jerry 464
Kern, Peter 375
Kerr, Caron 520
Khabiri, Alireza 474
Khalambaheti, Thareerat 863
Khalid, Nabila 79
Khan, Rasheda 281, 933
Khan, Tariq A. 902
Khan, Wasif A. 609
Khandelwal, N. 432
Khatib, Rashid A. 95, 529, 537
Khawar, Nadeem 678
Khieu, Virak 26
Khodiev, Aybek V. 744
Khusmith, Srisin 863
Kiang, Richard 185
Kiechel, Jean-René 506, 1006
Kifude, Carolyne M. 578
Kiggundu, Moses 706
Kihonda, Japhet 41
Killeen, Gerry 41, 95, 227, 261,
537, 672, 845, 848, 851
Kilpatrick, A. Marm 467, 657
Kim, Andrea 17
Kim, Chang-Hyun 1040
Kim, Hyo-Jin 567, 608
Kim, Jung-Yeon 267, 538
Kim, Jeong-Su 538
Kim, Tong Soo 267, 284, 538
Kim, Tae Im 284
Kim, Young-A 157
Kim, Yeon-Joo 538
Kimber, Michael J. 953
Kimmel, Rhonda 303
Kindermans, Jean-Marie 974
Kines, Kristine J. 289, 1010
King, Chwan-Chuen 105
King, Christopher L. 153, 296, 301,
551, 552, 803
King, Christopher 304
King, Christopher C. 159
King, Charles H. 461, 540, 699
King, C. R. 11, 48
King, Russell 583
King, Richter C. 581
Kinney, Richard M. 1, 114, 471, 660
Kinsey, J. 730
Author Index
Kinyanjui, Sam 550
Kioko, Elizabeth N. 598
Kippes, Christopher 461
Kiprotich, Chelimo 557
Kiptui, Rebecca 546
Kirby, Matt 258
Kirchhoff, Louis V. 478
Kirsch, Philipp 68, 402, 585, 889
Kissinger, Patricia 473
Kiszewski, Anthony E. 891
Kitagawa, Beatriz Y. 997
Kitchen, Lynn W. 102
Kitron, Uriel 67, 392, 394, 1060
Kitua, Andrew Y. 843
Klade, Christoph 122, 687
Klein, Eili 532
Klein, Philipp 637
Klein, Pamela W. 555
Klein, Sabra 277, 555, 959
Klena, John 906
Kleshchenko, Yuliya 154, 648
Klimov, Alexander 681
Kline, Daniel L. 1025
Klinger, Elissa V. 1062
Klinger, Jeff 652
Klion, Amy D. 390, 952
Klungthong, Chonticha 765
Knapp, Jenny 377
Kneen, Rachel 1042
Knepper, Randall G. 599
Knight, Matty 1033, 1049, 1050
Knols, Bart G. 1024
Ko, Albert I. 98
Kobbe, Robin 637
Kochel, Tadeusz 115, 444, 928,
930, 957
Koekemoer, Lizette L. 591
Koenraadt, Constantianus J. M. 66,
592
Koita, Ousmane A. 508, 510, 639,
856
Kolb, Carol 737
Kole, Abhisake 952
Kolhe, Priti 464
Kollaritsch, Herwig 122
Komaki-Yasuda, Kanako 208
Komar, Nicholas 462
Komatsu, Natália T. 697
Komisar, Jack L. 1015
Konadu, Peter 389
Konate, Siaka 952
Kone, Abdoulaye K. 14, 1058
Kone, Cheick O. 1057
Kongsin, Sukhontha 28, 764
Konovalova, Svetlana 48
Koonce, Joseph 461
Koplowicz, Yelena B. 996
Koram, Kwadwo A. 103, 192, 211,
597
Korenromp, Eline 937
Korir, Cindy C. 806
Korir, Jackson C. 199
Korten, Simone 949
Koru, Ozgur 431, 810
Kosasih, Herman 681, 766
Kose, Sukran 900
Kosek, Margaret 541, 866
Kosmowski, Andrew 1008
Kosoy, Michael 330, 331, 908, 913
Kosoy, Olga L. 1043
Kotea, Navaratnam 690
Kotloff, Karen L. 326, 382, 740,
917
Kou, Zhihua 3
Koumare, Sekou 1057
Kouri, Drew 181, 540
Kourouma, Kerfallah 186, 259
Kowalewska-Grochowska, Kinga
815
Kowuour, Dickens 557
Krairojananan, Panadda 515
Kramer, Erin 315
Kramer, Laura D. 467, 657, 659,
661, 662
Krause, Darren R. 563
Krause, Peter J. 1045
Krautz-Peterson, Greice 333
Kreishman-Deitrick, Mara 656, 817
Kremer, Laurent 505
Kremsner, Peter G. 10, 523
Krishnegowda, Gowdahalli 1020
Krogstad, Donald J. 177, 508, 509,
510, 514, 560, 639, 839, 856
Krolewiecki, Alejandro J. 89
Kroon, Erna 991
Krudsood, Srivicha 519, 811, 1006
Krulak, David 415
Kruszon-Moran, Deanna 101, 134
Krzych, Urszula 319
Ksiazek, Thomas G. 281, 955
Kuan, Guillermina 86, 110, 684
Kucerova, Zuzana 147
Kuete, Thomas 717
Kuhn, Stephanie 473
Kuikumbi, Florent M. 476
Kulasekara, Bridget 49
Kulkarni, Manisha A. 245
Kulkarni, Prasad 384
Kum-Arb, Utaiwan 218
Kumar, Anil 85
Kumar, Ashwani 673
Kumar, Nirbhay 40, 325, 1012
Kumar, Sanjay 85
Kumar, Sanjeev 39, 243, 941, 1037
Kumar, Sanjai 1017
Kumar, T. R. Santha 505
Kumar, Tripurari 742
Kumaran, Paul 666
Kumarapperuma, Sidath 923
Kumaraswami, V. 666
Kumwenda, Taida 938
Kun, Juergen F. J. 523
Kunert, John 1030
Kunz, Susan 975
Kuppers, Rudolf 1009
Kurane, Ichiro 107, 686
Kurtis, Jonathan 70, 322, 335
Kuschner, Robert A. 429
Kuser, Paula R. 570
Kutcher, Simon 644
Kuzera, Kristopher 264
Kwak, Dong-Hwan 157
Kweka, Eliningaya J. 57
Kwon, Joon-Wook 538
Kwon, Yong-Kuk 994
Kyle, Dennis E. 173, 174, 503
Kyle, Jennifer L. 6, 116
L
La Beaud, A. Desiree 461
Labo, Maria N. 995
Lacerda, Henio G. 313
Lachowitzer, Jeff 1054
Lackovic, Kurt 554
Lacma, Julio 884
LaCrue, Alexis N. 490, 493, 798,
861
Lad, Alpana 452
Ladd, Aliny B. L. 752
Ladd, Fernando V. L. 752
Lafontant, Christina 177, 184
LaForce, Marc 384
Lafuente, Maria-Jose 171
Lafuente, Sarah 8, 572
Laguna, V. A. 957
Lai, Ching-Juh 457
Laihad, Ferdinand J. 736
Lakwo, Tom 770
Lal, Altaf A. 971
Lal, Chandra S. 85
Lalloo, David G. 1003
Lama, Marcel 223
Lamb, Erika W. 293, 309
Lambert, Lynn 576
Lambert, Lynn E. 47
Lambson, Bronwen E. 247
Lameyre, Valerie 421, 716, 717
Lamikanra, Adebayo 741
Lammey, Jovitha 1007
Lammie, Patrick J. 890, 988
Lampah, Daniel 354, 486, 701
Lampman, Richard 1040
Lanar, David E. 45, 158, 218, 303,
863
Lanata, Claudia F. 903
Lancaster, Kathryn 266
Lanciotti, Robert S. 1043
Lander, Eric S. 162, 368, 369
222
Landis, Sarah 703
Laney, Sandra J. 1014
Lang, Jean 344, 443, 451, 454
Langdon, Gretchen 70
Langerveld, Anna 982
Langevin, Stanley A. 660
Langhorne, Jean 193
Lanteri, Charlotte 650
Lanzaro, Gregory C. 1024
Laoboonchai, Anintita 832
Laras, Kanti 104
Larasati, Wita 104
LaRocque, Regina 18
Larson, Bruce A. 339
Lascano, Mauricio S. 400
Laserson, Kayla 15, 338, 339, 351,
546
Lau, Audrey O. T. 603
Laufer, Miriam K. 530, 834, 969,
1053
Laughinghouse, Andre 1039
Laughlin, Larry 332
Laupert, Fernanda 997
Laurens, Matthew B. 834
Laveen, Janeen J. 1043
Law, Angela S. F. 501
Lawrence, Kendra 63
Lawson, Bernard 388
Lawyer, Phillip G. 318, 396
Laxminarayan, Ramanan 532
Lay, Jenny 438
Lazar, Lidia E. 724
Le, TL 207
Le Anh, Nguyen P. 644
Le Bras, Jacques 831
Le Roch, Karine 369
Leach, Amanda 8, 572, 578
Leary, Kevin 520
Lebowitz, Jacob 576
Lee, Byung-Chul 538
Lee, Clarence M. 149, 1049
Lee, Eng-Hong 212
Lee, G.T. 165
Lee, Jo Woon Yi 567
Lee, Jo Woon Yi 608
Lee, Jin-Ju 567, 608
Lee, John S. 598
Lee, Moses 36, 166
Lee, Patricia J. 656, 817
Lee, Rebecca 46
Lee, Sydney 276
Lee, Sunhee 805
Lee, Young-Hee 267
Leelaudomlipi, Surasak 515
Leepin, Angela 605
Legorreta-Herrera, Martha 188
Legros, Dominique 974
Lehmann, Tovi 226, 588, 876, 945,
1022
Lehner, Claudia 122
Author Index
Leiby, David 196, 606, 1044
Leke, Rose Gana Fomban 425, 559
Leliwa-Sytek, Aleksandra 649
Lell, Bertand 10
Lelo, Baliyima 843
Lemiale, Laurence 216
Lemma, H. 718
Lemnge, Martha M. M. 842, 843
Lemos, Denise 291
Lengeler, Christian 337
Lenhart, Audrey 232
Lennon, Niall 25
Leon, Ilsa 1073
Leon, Renato 601
Leon, Walter 884
Leontsini, Elli 30
Lepec, Richard 725
Lerdthusnee, Kriangkrai 330
Lertora, Juan J. L. 514
Lesauvage, Eric 716
Lescano, Andres G. 19, 30, 104,
749, 903
Lescano, Willy 884
Lesho, Emil 395
Leszczynski, Sara 1037
Letson, William 768
Leung, Daniel 313
Leung, Lawrence W. 927
Levasseur, Kathryn 369
Levert, Keith 274
Levin, Michael 452
Levine, Gail L. 11
Levine, Myron M. 326, 740
Levy, Karen 51, 52, 328
Levy, Marc 995
Levy, Michael Z. 627, 786
Lewey, Jennifer 734
Lewis, Drew 517
Lewis, Dorothy E. 610
Lewis, Edwin E. 561
Lewis, Sheri 104
Lewockzo, Kenneth 260
Lewthwaite, Penelope 1042
Leyva, Rene T. 996
Li, Ben-Wen 777, 780
Li, Cong 882
Li, Chenglong 1002
Li, Qigui 167, 168, 169, 170
Li, Qianjun 923
Li, Robert S. 290
Li, Sheng 48
Li, Shunyu 284
Li, Wenjun 453
Li, Xioaming 920
Li, Xinshe 1011
Li, Yi-Shiuan 105
Li, Yuesheng 290
Li, Yu 991
Li, Yan B. 71
Li, Zheng Z. 71
Libiszowski, Paul C. 844
Libraty, Daniel H. 5
Libreros, Gerardo A. 759
Liebman, Katherine 655
Liepinsh, Dmitry 558
Lievens, Marc 8, 10, 572, 578
Lijek, Rebeccah S. 741
Liles, W C. 164, 799, 1018
Lilley, Ken 187
Lim, Chang k. 686
Lim, K.C. 292
Lim, Pharath 811
Lim, Phawath 831
Lima, Aldo A. M.. 745, 748, 752,
753
Lima, Danielle M. 757
Lima, Flavia L. 482
Lima, Jose B. Pereira. 882
Lima, Josane R. 313
Lima, Jose W. 479
Lima, Maria F. 154, 648
Limbach, Keith 11, 48, 304, 581
Limpawattana, Panita 428
Limsalakpetch, Amporn 218
Lin, A.J. 650
Lin, Enmoore 159, 181, 301, 1007
Lindsay, Steve W. 41, 227, 258,
594, 845, 848, 851
Linnen, Jeff 348
Linser, Paul J. 942
Linthicum, Kenneth J. 65, 262, 989
Liscum, Kathleen R. 610
Little, Mark P. 772
Liu, Chung-Ming 105
Liu, Canhui 363
Liu, Jun 920
Liu, Ping 5
Llamosas, Monica 29
Llanos, Alejandro 206
Llergo, Jose-Luis 171
Llinas, Manuel 1073
Loan, Huynh Thi Kim 456
Locke, Emily 48, 812
Logue, Christopher H. 993
Logvinenko, Tanya 18
Lok, James B. 984, 1011
Loker, Eric S. 285, 336
Lokida, Dewi 681
Lokomba, Victor 703
Lompo, Zourata 709, 709
Londono, Berlin 177, 560
Long, Carole A. 13, 47, 48, 213,
303, 803
Longacre, Shirley 214
Longstreth, J 519
Looareesuwan, Sornchai 506, 519,
811, 1004, 1006
Lopansri, Bert 486
Lopes, Maria Beatriz 753
Lopez, Eva 171
Lopez, Gaylord 59
Lopez, Victor 623, 930
Lopez-Lopez, Patricia 152
Lopez-Sanchez, Miriam 656, 817
Lopez-Vallejo, Fabian 271
Lord, Cynthia 121
Lorono-Pino, Maria Alba 465, 893
Loschen, Wayne 104
Lougué, Guekoun 833
Louie, Karen L. 659
Loukas, Alex 987
Lourenço, Elaine V. L.. 137
Lovegrove, Fiona E. 799, 1018
LoVerde, Philip T. 286, 291, 1032
Lovin, Diane 874
Lowery, Roy J. 490
Lozano, Sonia 511, 826
Lozano-Fuentes, Saul 892, 893
Lu, Jeff 367
Lu, Lydia 16
Lu, Liang 691
Lubaki, Jean-Pierre F. 476
Lubell, Yoel 343
Luby, Stephen P. 281, 933, 955,
1041
Lucas, Carmen 475, 526
Lucchi, Naomi W. 194
Lucena, Herene B. 748
Lucio-Forster, A. 399
Lucke, Andrew 165
Luckhart, Shirley 242, 249, 251,
561, 977
Lukeman, Ibrahim 637
Lukens, Amanda K. 162, 368
Lum, Lucy 28, 764
Lumsden, Joanne 319
Lun, Cheng-Man 299, 1029
Luna, Concepción 89
Lundstrom, Tammy S. 719
Lungu, Christopher 841
Luo, Haiyan 460
Luo, Yeung 460
Lusingu, John P. A. 842, 843
Lutumba, Pascal P. 481, 794
Luxemburger, Christine 349, 443,
451, 454
Lyimo, Thomas 21
Lyke, Kirsten E. 14, 216, 324, 1058
Lynch, Joseph 461
Lynch, Julia A. 445
Lyon, Jeffrey A. 12
M
Ma, Puo-Hua 921
MacArthur, John R. 633, 676, 830
MacCallum, Fiona J. 550
Macedo de Oliveira, Alexandre 338,
339, 972
Macete, Eusebio 8, 306, 572
223
Mach, Ondrej 16
Machado, Eleuza R. M.. 137
Machado, Paulo R. L. 380
Machado, Paula R. L. 931
Machado, Rosangela Z. 482
Macharia, Stephen 476
Maciel, Andressa A. F. L. 748
Maciel, Jorge 1012
Maciel, Jamilly G. 745
MacIntosh, Victor 415
Macintyre, Kate 184
Mack, B. M. 856
Mack, Douglas G. 316
Mackenstedt, Ute 372
Mackenzie, Charles D. 387, 774,
982
MacLeod, William B. 535, 678
Madebe, Rashidi 842
Madeira, Andreza 997
Madison, M. Nia 154, 648
Madrid, Teresa M. 299
Madyarov, Ruslan S. 744
Magill, Alan J. 173, 174, 357, 415,
650, 1008
Maguiña, Ciro P. 381
Maguire, Jason D. 76
Maguire, James H. 627, 786
Mahajan, Babita 1017
Mahajan, R C. 521
Mahande, Aneth M. 57
Mahanta, J. 521
Mahanty, Siddhartha 213, 952
Maharaj, Payal D. 660
Mahi, Sushil 432
Maillard, Stephan 377
Main, Andy J. 646
Maina, Geoffrey 336
Maiolatesi, Santina 581
Maire, Nicolas 671
Majam, Victoria 1017
Makarem, Mazen 293, 311
Makieya, Eric 794
Makkiya, Adil 91
Makoka, Mwai 916
Malafronte, Rosely S. 697
Malaivichitnond, Suchinda 545
Malaquias, Luiz Cosme C. 291
Malasit, Prida 2
Malecela, Ezekiel K. 842
Malecela, Mwele 774
Malenga, Grace 530
Malhotra, Indu 153, 803
Malick, Ndiaye 553
Malila, Aggrey 633
Malkin, Elissa 213, 812
Malla, Nancy 521
Mallik, Arun K. 789
Maloney, Susan 327, 329, 330, 908,
911, 915
Mamadou, Diallo A. 553
Author Index
Mammen, Mammen P. 2, 429, 760,
763
Manaca, Maria N. 8, 9, 572
Manalo, Daria L. 70
Manchery, John 432
Mancini, Emiliano 871
Mand, Sabine 388, 389
Manda, Hortance 1026
Mandalakas, Anna M. 461
Mandalasi, Msano 334
Mandaliya, Kishor 803
Mandomando, Inacio 8, 9, 306, 572
Mangara, Salif 508
Mann, Victoria H. 289, 1010
Mannix, Frank 130
Manoukis, Nicholas C. 588, 868
Manrique, C. 957
Mansor, Sharif 506
Manuel, Karla R. 438
Manya, Ayub 546
Maqbool, Sajid 678
Mara, Valentina 995
Marathe, Chaitra 150
Marcet, Paula L. 67, 394
Marchena, Loyd 118
Marchetti, Elisa 384
Mare, Daouda 709
Marfo-Debrekyei, Yeboah 388, 389
Marfurt, Jutta 973
Margolis, Harold S. 26, 768
Mariani, Giuseppe 374
Marinho, Claudio R. F. 800
Markus, Miles B. 221
Marovich, Mary 317
Márquez-Navarro, Adrián 269
Marquino Quezada, Wilmer 972
Marra, Peter P. 467
Marrama, Laurence 214
Marron, Jennifer 347
Marrs, Carl 328
Marsh, Kevin 300, 550, 554, 1058
Marshall, Jonathon C. 872
Marshall, John M. 205
Marshall, Kristy 713
Martensson, A. 1005
Martin, Gregory J. 747
Martin, Laura B. 47, 213, 573, 576
Martin, Thibaud 230
Martinez, Idali 472
Martins, Daniella R. 313
Martins, Lívia C. 123, 131
Martins, Maria P. S.. 1047
Martins-Filho, Olindo A. 291
Martinson, Jeremy 321, 548
Marty, Francisco 1045
Marzouk, Mahmoud M. 79
Masanja, Irene 342, 499
Mason, Carl J. 744
Mason, Peter W. 658
Masood, Tahir 678
Massey, Holman C. 984
Massougbodji, Achille 651
Masunge, Japhter 16, 17
Masuoka, Penny 332
Maswi, Charles 676, 830
Mather, Michael W. 855, 857, 858,
859
Mather, Thomas N. 1061
Mathieu, Els 720
Mathisen, Glenn E. 478
Matos, David 738
Matson, Ryan 541, 866
Matsuda, Shusaku 484
Matsumoto, Kotaro 901
Matsunaga, James 98
Matthys, Barbara 729
Matuschewski, Kai 319
May, Jürgen 637
May, Karen 803
Mayor, Alfredo 306
Mazitschek, Ralph 652, 821
Mazumdar, Suman 222
Mbacham, Wilfred 635
Mbewe, Bernard 808
Mbogo, Charles M. 248
Mboup, Soulyemane 162, 368, 369,
935, 1021
McArthur, Julie H. 347
McAvin, James 444
McBride, Alan J. A. 98
McBride, Flavia W. C. 98
McCall, Philip 232
McCall, Suzanne 714
McCalla, Carlo 1045
McCallum, Fiona J. 300, 551
McCalmont, William F. 650, 656,
817
McCann, James 891
McCarthy, Anne E. 427
McCarthy, James 433
McCarthy, Sarah E. 611
McCasland, Michael 12, 219
McClellan, Holly A. 573
McCollum, Andrea M. 971, 972
McComas, Katherine 66
McConnell, William 517
McCutchan, Thomas 1017
McDowell, Mary Ann 64, 395, 397,
670
McElroy, Peter 21
McGarvey, Stephen T. 70
McGee, Charles E. 613, 658
McGrath, Andrew 48
McGrath, Shannon M. 44
McKelvey, Robin 624
McKerrow, James H. 292
McLain, James D. 618
McLaughlin, John R. 68, 402, 585
McLeod, John 461
McManus, Donald P. 71, 290, 1051
McMorrow, Meredith 342
McNeil, Yvette 486
McRae, Scott 473
Mduluza, Takafira 325
Mead, Daniel 464
Mease, Ryan 12, 215
Medeiros, Marco 98
Medina, Deysi 1046
Medina, Sarimar 47
Medina-Franco, José L. 271
Medlin, Carol A. 737
Meeks, Janet 23
Meheus, Filip 481, 794
Melby, Peter C. 739
Melrose, Wayne 268, 713, 771
Membi, Christopher D. 163
Mendenhall, Ian 886
Méndez, Fabián 759
Mendez, Juan 480
Mendez-Cuesta, Carlos A. 273
Mendoza, Alfonso 171, 505
Mendoza-Silveiras, José 11, 216,
304, 581
Menéndez, Clara 306
Menezes, Anisha 235
Menezes, Cristiane A. S.. 316
Menezes, José A. S. 997
Meng, Zhaojing 665
Menge, David M. 814, 853
Mensah, Nathan 103
Menten, Joris 937
Mentink-Kane, Margaret M. 667
Meola, Mark A. 662
Meola, Mark M. 657
Mercado, Xiomara 472
Merino, Emilio F. 850
Meroni, Valeria 72
Mesesan, Kyeen 1
Meshnick, Steven R. 228, 519, 693,
703, 808, 811, 816
Mesirov, Jill 369
Messerli, Shanta M. 288
Mesu, Victor K. Betu. Ku. 476
Metenou, Simon 425, 952
Metta, Emmy O. 21, 529
Mettens, Pascal 44, 218
Metwally, Mohamed 731
Meya’a, Abanda 722
Meyer, Andrew M. 888
Meymandi, Sheba K. 478
Meza, Rina 750
Meza, Yocelinda 750
Mharakurwa, Sungano 229, 569,
677, 838, 896, 938
Miaka, Constantin 481
Michaels, Sarah 1034
Michon, Pascal 159, 301, 551, 809
Middeldorp, Jaap M. 303
Midzi, Nicholas 325
224
Miesfeld, Roger L. 234, 235, 236,
975, 976
Miguel, Ihosvani 813
Mikhail, Nabiel 731
Miles, K. 207
Milhous, Wilbur K. 173, 174, 357,
415, 503, 524, 527, 650, 1009
Militello, Kevin T. 1013
Milkowski, Anna 602
Miller, André 1033, 1049, 1050
Miller, Barry R. 1
Miller, David 992
Miller, John M. 543, 674, 841, 844
Miller, Kathryn 266
Miller, Louis H. 13, 47, 213, 488,
573, 576
Miller, Mark 383
Miller, Nathan J. 1061
Miller, Robert 735
Miller, R. Scott 1009
Miller, Scott 863
Millman, Jessica 8, 9, 572
Mills, Anne 343, 936
Mills, Lisa A. 96
Milner, Dan A. 162, 204, 368¸
1021, 1053
Mimori, Tutsuyuki 89
Minta, Anna 180
Mintwo, Alain F. 476
Mintz, Eric 15
Miranda, Maria Consuelo 797
Miri, Emmanuel S. 422
Mis-Avila, Pedro 893
Misher, Lynda 49
Misiani, E. A. 591
Mitamura, Toshihide 564
Mitova, Rumiana 373
Mitre, Edward 775, 948
Mitreva, Makedonka 362, 779, 985
Miura, Kazutoyo 13, 213
Mkoji, Gerald M. 336
Mkulama, Mtawa 229, 838, 938
Mlambo, Godfree 1012
Mmbando, Bruno P. 842, 843
Mobedi, I. 399
Moch, J K. 1015
Moguel, Barbara 403
Mohamady, Hanan I. 906
Mohamed, Abdirahaman 543
Mohamed, Ahmed 619
Mohamed, Abdirahman 674, 844
Mohammed, Hamish 348
Mohareb, Emad 925
Mohmmed, Asif 222, 566
Molaei, Goudarz 257, 602
Molina, Margarita 903
Molina-Cruz, Alvaro 243, 1037
Molta, Norman 692
Molyneux, Malcolm E. 530, 693,
1003
Author Index
Moncayo, Abelardo C. 260
Mondal, Dinesh 964, 966
Mondo, Mireille 466, 689
Monroy, Carlota 403
Monroy-Nicola, Jorge 400
Montero-Solis, Ciro 852
Montes, Martin 986
Montes-Jave, Cecilia 884
Monteville, Marshall 925
Montgomery, Joel 955
Montgomery, Jacqui 1003
Montgomery, J. M. 930, 957
Montgomery, Phil 368
MonThavy, Chea 82
Montoya, Manuel 332
Montoya, Romeo H. 28, 764
Moody, Erin 260
Moonga, Hawela 539
Moore, Aubrey 402, 585
Moore, Brioni R. 501, 638
Moore, Chester G. 888
Moore, Lee R. 809
Moormann, Ann M. 303, 556, 557
Mootha, Vamsi 489
Mor, Siobhan M. 426
Moraes-Ávila, Sandra L. 697
Morales, Maria E. 289, 1010
Moran, Manuel 19, 683
Moran, Marjorie 433
Morazzani, Elaine 643
Moreau, Jean Charle 553
Moreno, Elizabeth C. 291
Mores, Christopher N. 125, 470,
582
Moretz, Samuel E. 13, 47, 48
Morgan, Daniel J. 380
Morgan, Rachel 1002
Morgan, William 288
Morin, Laura-Lee L. 662
Moris, Philippe 9
Morris, D. 519
Morrisey, Joanne M. 365, 857, 858,
859
Morrison, Amy 623
Morrison, A. C. 930
Morrison, Dennis 344
Morsy, Zakariya S. 361
Morton, James 975
Morway, Christina 330, 331, 908
Mosher, Aryc 700, 849
Mosnier, Joel 818
Mota, Maria M. 1019
Mott, Robert 1008
Mott, Tiffany M. 561
Motter, Christi 996
Moudy, Robin M. 657, 662
Moulds, Joann M. 1058
Moulton, Lawrence H. 30
Mowlavi, G. R. 399
Moyano, Luz Maria 31
Mpimbaza, Arthur 352
Mpoto, Alfred M. 476
Mridha, Liz 517
Msangeni, Hamisi A. 842
Mshinda, Hassan 261, 676, 848,
851
Msiska, Charles 355
Mtasiwa, Deo 41, 227, 261, 845,
848, 851
Mu, Jianbing 209, 1039
Mubi, Marycelina 163
Muchiri, Eric M. 153, 699
Mucker, Eric 992
Muehlenbachs, Atis 1054
Mueke, Jones M. 595
Mueller, Ivo 159, 181, 301, 550,
551, 552, 809, 1007
Mueller, Norbert 963
Mugyenyi, Cleopatra K. 300, 554
Mukabana, Richard 401
Mukaka, Mavuto 1003
Mukbel, Rami M. 64, 142, 143,
395, 397
Mukherjee, Shankar 146
Mukherjee, Sudeshna 260
Mukuka, Chilandu 543, 674, 841
Mulenga, Musapa 229, 938
Mulet, Teresa 512, 513
Mullen, Gregory E. 13, 47, 213, 576
Muller, Claude P. 682
Müller, Ivo 973
Muller, Michaela 1068
Müller, Pie 865
Müller-Myhsok, Bertram 785
Munayco, Cesar V. 104, 728
Mundaca, Cecilia 104
Mundaca, Carmen C. 19, 683, 728
Mungai, Peter 153
Mungai, Peter L. 699
Muniz, Andre Luiz A. 283
Muniz, Pascoal T. 697
Muñoz, Jorge 348
Muñoz, Maria de L. 106
Muñoz-Jordán, Jorge 112, 754
Munungi, Auguy K. 476
Muok, Erick M. O. 310
Murcia, Luz Mila 837
Murphy, Brian R. 124, 347
Murphy, Jittawadee 330
Murphy, Jennifer L. 56
Murray, Clinton K. 429, 714, 715
Murray, H, W. 378
Murtaza, Asifa 678
Musa, Dankyau 494
Musafiri, Placide 734
Musie, Edgar M. 922
Muskus, Carlos 249
Musset, Lise 940
Musuamba, Gertrude 228
Mut-Martin, Mirza 151
Mutabingwa, Theonest K. 322,
1054
Mutai, Beth K. 1016
Mutuku, Francis 587, 595, 1036
Mutumanje, Elissa A. 434, 436
Muturi, Ephantus J. 248
Muvdi, Sandra H. 84
Mwakitalu, Esther 774
Mwangangi, Joseph M. 248
Mwangoka, Grace W. A. 176
Mwanza, Mercy 841
Mwapasa, Victor 693
Mwinzi, Pauline
Mwinzi, Pauline N. M. 307, 310,
664
Myatt, Mark 722
Myers, Jocelyn Celeste 1033, 1049,
1050
Myint, Khin S. A. 113, 429
Myles, Kevin M. 643
Mzayek, Fawaz 510, 514, 639
N
N’Goran, Eliézer K. 729
N’Guessan, Raphael 230
Na, Byung-Kook 267
Na Ayuttaya, Tippawan T. 618
Naddaf, S. R. 399
Naemkhunthot, Sirirat 107
Nagajyothi, Fnu 146
Nagao, Yoshiro 111
Nagpal, Avinash C. 194, 1055
Naguleswaran, Arunasalam 75
Nahar, Kamrun 281
Nahar, Nazmun 933
Najafi, N. 399
Najera-Vazquez, Maria del Rosario
893
Nakao, Minoru 72, 375
Nakhla, Isabelle 906
Nakhlla, Isabelle 905
Nakielny, Sara F. 995
Nam, Vu S. 644
Nanda, Nutan 183
Naniche, Denise 9
Nankabirwa, Joaniter I. 93
Naorat, Sathapana 327, 911
Naranjo, Nelson 249
Narayan, Rupa 631
Nardin, Elizabeth 46
Nartey, Helena 192
Narum, David L. 49, 213, 576
Nascimento, Eliana L. 313
Nascimento, Marcia C. 283
Nascimento, Renata T. 120
Nash, Lisa 651
Nash, Oyekanmi 994
Nathan, Michael B. 350
225
Natividad, Filipinas 119
Navaratnam, Vis 506, 1006
Navarrete, Joel 106
Navas, Adriana 797
Ndao, Momar 815
Nde, Pius N. 154, 648
Ndeezi, Grace 352, 426
Ndhlovu, Micky 355
Ndiaye, Daouda 162, 204, 368,
369, 489, 935
Ndiaye, Hawa 710
Ndiaye, Jean-Louis 717
Ndiaye, Magueye 689
Ndikuyeze, Georges 1037
Ndip, Lucy M. 1064
Ndir, Omar 162, 369, 935, 1021
Ndububa, Dennis 651
Ndugu, Ibrahim 336
Neafsey, Daniel E. 162, 368, 579
Nébié, Issa 846
Nechmireva, Tamara S. 744
Neil, Donald A. 415
Neira, Marco 601
Nelson, Kara 51, 52
Nene, Vish M. 1033, 1050
Neres, Rita 800
Nerome, Reiko 686
Nerurkar, Pratibha V. 460
Nerurkar, Vivek R. 460, 468, 958
Neto, Armando M. 225
Nettel-Cruz, Jose A. 852
Neuhaus, Ellen 1045
Neva, Franklin A. 135
Nevin, Remington 438
Newland, Joseph 47
Ng’ang’a, Z. 549
Ng’habi, Kija R. 1024
Ngajilo, Aggrey 633
Ngan, Chantha 26
Ngasala, Billy 163
Ngoa, Nguyen D. 94
Ngoenwiwatkul, Yaowaluk 924
Ngondi, Jeremiah 700, 849
Ngudiankama, Barbara F. 240
Nguku, Patrick 619
Nguon, Chea 83
Nguyen, Andrew 507
Nguyen, H.P. 207
Nguyen, Megan 196
Nguyen, N.Q. 207
Nguyen, Ngoc Rang 451
Nguyen, Q.H. 207
Nguyen, Thi Kim Tien 451, 454
Nguyen, Trong Toan 451, 454
Nguyen, Vu 576
Nguyen Than, Ha Quyen 22
Nguyen Thanh, Hung 22
Nguyen Thi, Phuong Dung 22
Ngwa, Alfred A. 210
Nhampossa, Tacilta 306
Author Index
Nicoll, William S. 158
Nieberg, Paul H. 478
Nielsen, Carrie 459
Niezgoda, M. 957
Nikiema, Jean Baptiste 709
Nikolajczyk, Barbara 664
Niles, Edward G. 1032
Nimmannitya, Suchitra 453
Nimmo, Graeme 268
Nisalak, Ananda 2, 113, 453, 760,
763, 765, 767
Nitayapan, Sorachai 618
Nithyanandan, Nagercoil 520
Njama-Meya, Denise 675
Njau, Joseph D. 633
Njenga, Kariuki 619
Njikap, Adelaide 722
Nkrumah, Louis J. 505
Nku Imbie, David 228
Noedl, Harald 636, 832, 934
Nofchissey, Robert A. 129, 663
Nogbou, Messoum 496
Nogueda-Torres, Benjamina 269
Noisakran, Sansanee 2
Noor, Abdisalan 546, 546
Norris, Douglas E. 229, 250, 591,
879, 896, 938, 959
Norris, Laura C. 879
Nosten, François 1005
Notsch, John 650
Nour El-Din, El-Shaimaa M. 61
Novak, Robert J. 246, 248, 252,
1040
Novelli, Enrico M. 353
Nuchprayoon, Surang 784
Nuernberg, Peter 388
Nukui, Yoko 686
Nunes, Márcio R. T. 123, 131, 755
Nuñez, Andrea 25, 110
Nunez, Gladys 747
Nurhayati 766
Nutman, Thomas B. 135, 390, 665,
666, 667, 950, 952
Nwagwu, Mark 193
Nwakanma, Davis 197, 210, 812
Nwankwo, Lucky 147
Nwigwe, Ugonna F. 420
Nwoke, Betram E. B. 100, 413
Nwuba, Roseangela I. 193
Nwugba, Rose-Angela 524
Nyaguara, Amek 15
Nyakoe, Nancy K. 323
Nyame, Anthony K. 334
Nyika, Dickson 261
Nzarubara, Bridget 675
Nzila, Alexis M. 827, 828
O
O’Brochta, David A. 240, 945, 946
O’Connor, Linda-Lou 875
O’Guinn, Monica L. 598
O’Leary, Dan 473
O’Neal, Seth 380
O’Neil, Michael T. 187
O’Neill, Scott L. 979
O’Reilly, Ciara E. 15
O’Reilly, Michael 960
O’Riordan, S.P. 207
Oakley, Miranda 1017
Oaks, Edwin 750
Obadofin, Michael 692
Obara, Marcos T. 997
Obaro, Stephen 20, 353
Obeng-Adjei, George 195, 198
Ocampo, Clara 886
Ocaña-Mayorga, Sofia 400
Ochieng, Benjamin 15
Ockenhouse, Christian F. 219
Ocran, Anastasia R. 190
Odaibo, Alexander B. 155, 193, 547
Odunga, Oscar Amos 20, 353
Oduola, Ayoade M. J. 524, 527
Oduro, Abraham 103
Offianan, Toure A. 496
Ofori, Michael 192
Oguche, Stephen 651
Ogutu, Bernhards 12, 219, 735
Ohrt, Colin 173, 174, 357, 520,
650
Oishi, Kazunori 119
Ojurongbe, Olusola 523
Okafor, Christian M. F. 193
Okatcha, Tunika I. 839
Okebe, Joseph 197, 210
Okeke, Iruka N. 741
Okoko, Brown 384
Okyay, Pinar 788
Oladepo, Oladimeji 406
Olayemi, Oladapo 179
Oleinikov, Andrew V. 580
Oliveira, Bruna B. 752
Oliveira, Fabiano 395
Oliveira, Francisco M. B. 1032
Oliveira, Guilherme 286
Oliveira, Luiz F. 69, 396, 1039, 1052
Oliveira, Tricia M. 482
Olivier, Martin 977
Olley, Benjamin 404
Olliaro, Piero L. 378, 497, 506, 634,
968, 1005
Olorunsogo, Olufunsho O. 524
Olsen, Sonja 329
Olsen-Rasmussen, Melissa 991
Olson, Carol A. 476, 519, 811
Olson, Kenneth E. 231, 279, 441,
455, 641, 993, 1038
Olson, Victoria A. 614
Oluwagbenga, Ogunfowokan P. 494
Olveda, Remigio 335
Omar, O. A. 619
Omar, Thiaw 553
Omariba, Duke 735
Ombok, Maurice 587
Omer, Rihab A. O. 372
Omondi, Amos K’Ogal 353
Omosun, Yusuf O. 193
Onagan, Mario 708
Ong, Sivuth 26
Ong’echa, John Michael 20, 200,
321, 353, 548, 549, 694, 707,
1056
Onwuliri, Celestine O. E. 100, 413
Onyona, Phillip 338
Ooi, Mong How 1042
Opoka, Robert O. 695
Opondo, Dorothy 321
Orago, Alloys 20, 200, 321, 557
Oramasionwu, Gloria E. 178
Orengo, Jamie M. 649
Oria, Reinaldo B. 745, 748, 752,
753
Orlandi-Pradines, Eve 238
Oronsaye, Francis 910
Ortega, Oscar 86, 110, 684
Ortiz, Gloria M. 54
Osborne, John 274
Ose, Kenji 1027, 1035
Osei-Atweneboana, Mike Y. 386
Osinubi, Omowunmi Y. O. 99
Osman, Ahmed 1032
Osman, Rashid 619
Osorio, Jorge E. 114, 446, 471
Osorio, Lyda 837
Ospina, Marta C. 446, 758
Ostera, Graciela R. 487
Oswald, William E. 749, 903
Othoro, Caroline 46
Otieno, Kephas 338
Otieno, Michael 20, 200, 321, 557
Otieno, Richard 20, 200, 321, 353,
548, 549, 694, 707, 1056
Otieno, Walter 735
Otsuki, Hitoshi 208, 575
Ou, Ruguang 493, 798, 861
Ouattara, Amed 14
Ouedraogo, André Lin 846
Ouedraogo, Jean-Bosco 423, 424,
682, 709, 833, 835
Ouma, Collins 20, 200, 321, 353,
548, 549, 694, 707, 1056
Ouma, Peter 338, 339, 351
Ouma, Yamo 20, 549, 694, 707,
1056
Ovleda, Remigio M. 70
Owen, Robert 929
Owiredu, Williams K. B. A. 596
226
Owusu-Agyei, Seth 651, 726
Owusu-Ofori, Ruth 726
Oyakhiromen, Sunny 10
Özbel, Yusuf 61, 148, 788, 791
P
Pablo, Archie O. 70
Pachas, Paul E. 738, 898, 1046
Pacheco, Maria A. 860
Pacheco, Robinson 797
Padierna-Mota, Cecilia 269
Padilla, Carlos 738
Padilla, Gabriel 713
Padilla-Raygoza, Nicolas 787
Paessler, Slodovan 928
Page-Sharp, Madhu 1007
Pagés, Frederic 238
Paik, Ik-Hyeon 653
Painter, Heather J. 365, 858, 859
Pal, Subhamoy 444
Palacios, Ricardo 43
Palma, Patricia V. B. 757
Palmer, Dupeh R. 445
Palys, Tom J. 102
Pam, Sunday 692
Pandey, Basu D. 789
Pandey, Krishna 85
Pandey, Kishor 789
Panella, Amanda J. 1043
Pantenburg, Birte 610
Papadopoulou, Barbara 1068
Pape, W. J. 888
Parashar, Umesh 439
Pardo, Edwin H. 759
Paredes, Maribel 541
Parekh, Falgunee 216
Parida, Manmohan 617
Park, Daniel J. 162, 204, 579, 368
Park, Jae-Won 157
Park, Mi-Hyun 267, 538
Parker, William 923
Parmakelis, Aristeidis 872
Parmenter, Cheryl 958
Parra, Beatriz 759
Parra, Johanna A. 43
Parsons, Michele 15
Parsons, Marilyn 647
Parulekar, Varsha 384
Pasay, Cielo J. 433
Pascual, Mercedes 999
Passara, F. 957
Passos, Sara 380
Pastor, Giovanna 750
Patarakul, Kanitha 784
Patel, Jigar J. 854, 939
Patel, Nikki 995
Patel, Samir N. 632, 799, 1018
Patel, Vishal 652, 824, 1013
Author Index
Patra, Kailash P. 370
Patrican, Lisa A. 601
Patterson, J. L. 278
Patterson, Noelle B. 11, 48, 304,
581
Pau, Maria Grazia 44
Paulke-Korinek, Maria 122
Pearce, Edward J. 1010
Pearson, Mark S. 987
Pearson, Richard D. 313, 479
Pecor, James 598
Peel, Bethany A. 140
Pelleau, Stephane 831
Pelly, Tom 680
Penali, Louis K. 496, 651
Penha-Gonçalves, Carlos 800, 1019
Penhoat, Kristell 238
Pennington, James E. 234, 975, 976
Peou, Sok 934
Pérez, Gerardo 106
Perez, Juan 750, 884
Pérez, Ligia del Pilar 837
Pérez, Pilar 837
Pérez-Guerra, Carmen 109, 458
Pergam, Steven 663
Perkins, Douglas 20, 200, 321, 353,
548, 549, 694, 707, 1056
Perng, Guey 2
Perraut, Ronald 81, 214
Persson, Kristina E. M. 300, 550
Peruski, Leonard 327, 329, 330,
331, 908, 911, 915
Pesanti, Ed 1045
Pesce, John T. 309
Pesko, Kendra 121, 582
Peters, Jennifer M. 563
Petersen, Carolyn 10
Petersen, Christine A. 142, 143,
315
Petersen, Kimberly S. 653
Petersen, Lyle 348
Peterson, Ingrid 698
Peterson, Kristine 964
Peterson, Stefan 93
Peto, T.E. 207
Petri, William A. 964, 966
Petritus, Patricia M. 320
Pettifor, Audrey E. 228
Peyer, Martina 1076
Peyton, David H. 655
Pfarr, Kenneth 388, 389, 785
Pfeffer, Martin 463
Phillips, Rebecca 1071
Phoolchareon, Wiput 924
Phuc, Ha Van 456
Piacentini, Mauro 158
Piarroux, Renaud 377
Piccinali, Romina V. 394
Pichyangkul, Sathit 218
Pickering, Darren 987
Picot, Stéphane 968, 973
Pierre, Dorny 33
Piesman, Joseph 1060
Pilakasiri, Chaiyaphruk 783
Pilakasiri, Kajee 783
Pilotte, Nils 781
Pimentel, Guillermo 715
Pineda, Sandy 403
Pinedo-Cancino, Viviana V. 786
Pinel, J. 511
Piola, Patrice 1004
Pion, Sébastien D. 773, 776
Piper, Samantha N. 362, 778
Piriou, Erwan 303
Piscoya, Luis 31
Pitmang, Simon 651
Pitzer, Kevin 503
Plakson, Nicole 643
Pletnev, Alexander 124
Pletnikov, Mikhail 277
Plikaytis, Brian 384
Plouffe, David 369
Plowe, Christopher V. 14, 324, 421,
492, 530, 834, 969, 1053, 1058
Pochet, Nathalie 369
Poddar, Goutam 281
Pohlig, Gabriele 476
Polhemus, Mark 735
Polhemus, Mark E. 578
Pollack, Richard J. 244, 891
Polley, Spencer 302
Pollissard, Laurence 451
Polson, Hannah E. 214
Pompeu, Margarida M. 479
Ponce, Carlos 787
Ponce, Daphne 683
Ponce, Elisa 787
Pond-Tor, Sunthorn 335
Pongponratn, Emsri 604
Pongsiri, Montira 721
Pongsuwanna, Yoawapa 960
Pongtavornpinyo, Wirichada 936
Ponmee, Napawan 939
Ponnusamy, Loganathan 589
Poo, Jorge Luis 344
Porcella, Steve 964
Porta, Hirva 569
Porten, Klaudia 722
Porter, Kevin 115, 345, 346, 444
Porto, Aurelia F. 283
Portocarrero, Milagrytos 33
Posner, Gary H. 653, 1067
Potts, James A. 453
Poudiougo, Belco 712
Poulakakis, Nikolaos 872
Povoa, Marinete M. 882
Powell, Jeffrey R. 872
Powell, Michael 804
Powers, Ann M. 993
Pradel, Gabriele 36
Pradhan, Anupam 862
Pradines, Bruno 238, 818
Prager, Martín 797
Prajapati, Surendra K. 202
Prapasiri, Prabda 327, 924
Preaud, Jean-Marie 384
Premaratne, Prasad H. 191
Premji, Zul 163, 651, 1021
Presber, Wolfgang 864
Prestwood, Tyler R. 7
Preziosi, Marie-Pierre 384
Pri-Tal, Benjamin M. 944
Price, R N. 354, 486, 544, 701
Prichard, Roger K. 133, 386, 776
Pridjian, Gabriella 473
Prigge, Sean T. 367, 656, 817
Prigozhin, Daniil M. 7
Proano, Roberto 387
Proctor, Melanie C. 606, 1044
Prue Marma, Aung Swe 636
Pruett, Khadeeja 520
Puerto, Fernando I. 465
Pulliam, Juliet R. C. 956
Purcell, Lisa A. 36, 166
Purcell, Robert H. 959
Purfield, Anne E. 816
Pusic, Kae 305
Pusnik, Mascha 1070
Putaporntip, Chaturong 542, 545
Puthawathana, Pilaipan 960
Putnak, Robert 346
Putnam, Shannon 681
Puyol, Laura 306
Pybus, Oliver G. 616, 688
Q
Qadri, Firdausi 18
Qazi, Shamim A. 678
Qi, Yumin 871
Qian, Feng 576
Quaresma, Juarez A. S. 123, 131
Quashie, Neils B. 516
Queiroz, Jose W. 313
Queiroz, Nina M. Gual. Pimenta de.
482
Queiroz, Telma B. S.
Queiroz, Telma B. S. 479, 1047
Quelal, Claudia 837
Quelhas, Diana 306
Quinn, Matthew 3
Quinn, Thomas C. 96
Quinnell, Rupert 792
Quino, A. H. 416
Quiñones, Luz 112
Quinonez, Javier 403
Quintó, Llorenç 306
Quiroz, Evelia 118
Quispe, Jose 19
227
Quispe-Machaca, Victor 627
Qvarnstrom, Yvonne 810
R
Rachaphaew, Nattawan 515
Rada, Liliana 796
Raghavan, D. 90
Raghavan, Nithya 1049
Rahman, Mahmudur 281, 955
Rai, M. 378
Raj, Dipak K. 562
Rajan, Latha 733
Rajapandi, Thavamani 209
Rajatileka, Shavanthi 232
Ramalho-Ortigao, Marcelo 64, 395,
397
Ramanathan, Roshan 135
Ramanathan, Suresh 506, 1006
Ramboer, Isabelle 10
Ramer-Tait, Amanda 315
Ramey, Kiantra I. 147, 804
Ramhalo-Ortigao, Marcelo 670
Ramirez, Jhon 623
Ramirez, Jose L. 640
Ramírez, Luis R. 106
Ramirez, Ruth E. 758
Ramírez-Sierra, Maria J. 151, 152
Ramos, Celso 465
Ramos, Daphne D. 30
Ramos, Mary M. 112
Ramos, Simone G. R.. 137
Ramos-Avila, Adriana 188
Ramsey, Janine M 996, 1038
Ramzan, Afroze 678
Ramzy, Reda M. R. 360, 361, 1014
Rana, Saleem M. -. 522
Randeniya, Preethi V. 191
Randrianarivelojosia, Milijoana 717
Randrianasolo, Laurence 717
Ranford-Cartwright, Lisa 516
Rangel-Castilla, Leonardo 32
Ranson, Hilary 232, 865
Rao, P.V. Lakshmana 617
Rao, Ramakrishna U. 777, 779
Rasgon, Jason L. 870, 878, 980
Rasmussen, Sonja 473
Rath, Bruno 627
Rathod, Pradip K. 939
Ratsimbasoa, Arsene 717
Raviprakash, Kanakatte 115, 345
Raymond, JoLynne 992
Rayner, Julian C. 163, 847
Raza, Ahmed 1058
Razuri, Hugo R. 332
Rea, J 1001
Read, Amber L. 624
Recuenco, S. 957
Reddy, Heather L. 606
Author Index
Reed, Steven G. 141
Reeder, John C. 159, 973
Reese, Paul B. 132
Reeve, David 771
Regev, Aviv 369
Regis, David R. 11, 216, 304, 581
Regnery, Russell L. 614, 991
Reiling, Linda 300, 550
Reilly, Heather B. 160
Reinbold, Drew D. 820
Reis, Mitermayer G. 98
Reisen, William K. 459, 584, 601
Reiskind, Michael H. 582
Reist, Martin 97
Reiter, Karine 576
Remarque, Ed 192
Remich, Shon A. 735
Remoué, Franck 238
Ren, Xiaoxia 980
Renaud, François 38
Rendi- Wagner, Pamela 687
Rengifo, Graciela 759
Rengifo, Silvia 541
Renia, Fabrice 81
Renom, Montse 8, 9, 572
Renslo, Adam 292
Renteria, Ivy M. 371
Resoulinejat, Mehrnaz 743
Ressner, Roseanne 715
Restrepo, Berta N. 758
Restrepo, Marco 758
Reuter, Stefan 375
Revolorio, Leonicio 403
Reyes, Luisa 138
Reyes, Miguel 684
Reyes, Maria S. 216
Reyes, Sharina 11, 304
Reynolds, Kevin A. 817
Reynolds, Mindy 335
Reynolds, Mary G. 614
Reynolds, Steven J. 96
Reynoso-Ducoing, Olivia A. 273
Rezaeian, M. 399
Rezende, Antônio M. R. 568
Rhodes, Julia 329
Rhorer, Janelle 379
Riarte, Adelina 89
Ribeiro, Antônio Augusto C. M..
752
Ribeiro, Isabela 497
Ribeiro, Jose M. 665, 876
Rice, Janet 259
Richard, Patrice 81
Richards, Allen L. 434, 438, 1065
Richards, Frank O. 422, 700, 770,
849
Richards, Jean M. 627
Richards, Jack S. 300, 550, 551
Richardson, Jason H. 401, 598, 989
Richie, Thomas L. 11, 43, 48, 216,
217, 304, 412, 581
Ricklefs, Stacy M. 964
Rieckmann, Karl H. 173, 174, 187
Riehle, Michael A. 944
Riehle, Michelle M. 876
Rienthong, Somsak 327
Riley, Eleanor 197, 696
Ringwald, Pascal 968
Rios, M. 416
Rios, Melisa 837
Riscoe, Mike 822
Ritzhaupt, Larry 517
Rivera, Aidsa 112
Rivera, Pilarita T. 564
Rivera, Yisel A. 472
Rizvi, Mushahid A. 202
Robays, Jo 481
Robbins, Gillian E. 477
Roberts, Donald R. 60
Roberts, Reneè N. 490, 798, 861
Robich, Rebecca M. 244, 690, 891
Robinson, Amara L. 543, 674
Robinson, Jaimie S. 128
Robinson, Leanne J. 301
Robinson, Ralph D. 132
Rocha, Crisanta 25, 110
Rocha, C. 930
Rocha, Leonardo 43
Rocha, Manoel O. C.. 316
Roche, Claudine S. Moere
Tevahinetumataunurauarii 449
Rochette, Annie 1068
Rochford, Rosemary 303, 557
Rodas, Antonieta 403
Rodolfo, Carlo 158
Rodrigo, W. W. Shanaka I. 457
Rodrigues, Flávia G. R. 237
Rodrigues, Janneth 885
Rodriguez, Ane 171
Rodriguez, Ana 36, 166, 649
Rodríguez, Beatriz 512
Rodríguez, Glenda 836
Rodriguez, Mary L. 35, 371
Rodriguez, Rocio 627
Rodriguez, Richard 680
Rodriguez, Silvia 30, 31, 33, 35,
371
Rodriguez-Barraquer, Isabel 797
Rodríguez-López, Jannete R. 188
Rodriguez-Morales, Alfonso J. 796,
1000
Rodríguez-Morales, Sergio 270, 271
Roehrig, John T. 1
Roellig, Dawn M. 998
Rogayah, Hanifah 736
Rogers, Kathleen 609
Rogers, Matthew 792
Rogers, William 597
Rogerson, Stephen 552, 693, 808
Rogier, Christophe 238, 818
Rojas, Natalia 35
Rojas, Yanina 738
Roldan, William H. 381
Rollin, Pierre E. 281, 955
Romanos, Eduardo 512
Romero, Héctor 89
Romero-Estrella, Sagrario 996
Romero-Severson, Jeanne 874
Romig, Thomas 372
Romoser, William S. 601
Ronan, Jambou 553
Roncal, Norma E. 656, 817
Roncales, Maria 826
Roongruangchai, Jantima 783
Roonrruangchai, Kosol 783
Roper, Cally 569
Rosado-Paredes, Elsy 465
Rose, Angelika 433
Rose, Robert C. 3, 457
Rosenbaum, Paula 557
Rosenberg, Helene 390
Rosenberg, Melissa B. 382, 917
Rosenthal, Andrew S. 653, 1067
Rosenthal, Philip J. 340, 352, 423,
675, 705, 706
Ross, Amanda 671
Rossiter, Louise 433
Rossnagle, Eddie 580
Rota, Paul 281, 955
Rothman, Alan 24, 453, 765, 767
Rouamba, Noel 423, 424
Rouse, Petrica 229, 838
Roux, Kenneth 692
Rowe, Alexander K. 339
Rowe, Chris 49
Rowe, J. Alexandra 702, 1058
Rowland, Mark 230
Rowland, Michelle 1060
Rowton, Edgar 318, 483
Roy, Lipi 733
Roy, Manojit 959
Rubins, Kate 992
Rubio-Palis, Yasmin 867
Rueda, Leopoldo M. 881
Ruehlen, Nevada 55
Ruel, Theodore D. 705
Ruelas, Debbie S. 292
Ruiz-Espinoza, Gustavo E. 269
Rukmani, S 666
Rulisa, Stephen 635
Rupprecht, C. 957
Rush, Amy C. 777
Rush, Margaret A. 652, 821
Russell, Ian J. 1023
Rutta, Acleus S. M. 842
Ryan, Elizabeth M. 860
Ryan, Edward T. 18, 609
Ryan, Peter A. 644, 979
Ryder, Robert 703
228
S
Saad, Magdi 925
Saavedra-Rodriguez, Karla L. 626
Sabeti, Pardis C. 162, 368, 579
Sabin, Lora 535
Saborio, Saira 684
Sacarlal, Jahit 8, 9, 572
Sacchettini, James C. 505
Sacci, John B. 158
Sack, Christopher V. 68
Sackey, Sammy T. 198
Sacko, Noumouny 186, 259
Sadacharam, K. 666
Sadasivaiah, Shobha 224
Sadi, Johari 842
Sadofsky, Moshe 146
Sagara, Hawa 409, 710
Sagara, Issaka 421, 492, 635, 717
Sagay, Solomon 692
Sagno, Jean 186, 259
Sagoe, Miriam A. 275, 899
Sah, Binod K. 28
Saha, Sankar K. 1041
Sailor, Karen 722
Saintpere, Fabrice 81
Saito, Mariko 119
Saito, Mayuko 680
Sako, Yasuhito 72, 375
Salako, Lateef A. 179
Salam, Mohamed F. 361
Salanon, Christophe 442
Salanti, Ali 49
Salas, Carola J. 416, 525, 526
Salasek, Michael 1038
Salazar, Milagros 928
Saldarriaga, Emilia 683
Sales, George André F. 752
Salika, Prasert 327, 915
Salimnia, Hussain 719
Sall, Amadou Alpha 466, 689
Sallum, Maria A. 882
Salvador-Recatala, Vicenta 1031
Salvana, Edsel 358
Sam-Agudu, Nadia A. 695
Samake, Mariam 917
Samake, Youssouf 508
Samarakoon, Sajeewani U. 854
Same-Ekobo, Albert 717
Sammons, Scott 274, 991
Sampson-Johannes, A. 730
Samsi, Kiki M. 766
Sanchez, Cesar 986
Sanchez-Burgos, Gilma 152
Sanchez-Vargas, Irma J. 441, 455
Sandhu, Gurjinder 680
Sandoval, Claudia 1000
Sandoval, Marco A. 852
Sang, Rosemary C. 598
Sangare, Lansana 508
Author Index
Sangsuk, Leelaowadee 327, 329,
915
Sangweme, Davison T. 325
Sanogo, Kassim 421
Sanogo, Kassoum M. 382
Sanogo, Yibayiri O. 1040
Sanprasert, Vivornpun 784
Santana, Mirta 398
Santhosh, S.R. 617
Santiago, Gilberto A. 754
Santiago, Jose 55
Santillan, Frida 852
Santivañez, Saul J. 35, 371
Santolalla, Meddly L. 416, 526
Santolamazza, Federica 871
Santos, Cleiton 98
Santos, Eduardo M. Tarazona 568
Santos, Silvane B. 283
Sanz, Laura 171
Sanz, Sergi 306
Sarfati, Patrice 442, 443
Sarmiento, Maria 175
Sarr, Ousmane 162, 204, 368, 369,
1021
Sathe, Neeraj 124
Sattabongkot, Jetsumon 484, 515,
574, 575
Sauerwein, Robert 846
Saul, Allan 47, 213
Saunders, David L. 173, 174, 415,
1008
Savage, Mason Y. 59, 998
Sawanpanyalert, Pathom 107
Sawanyawisuth, Kittisak 428
Sawyer, L. 730
Saxena, Ajay 182
Saxena, Parag 617
Scanfeld, Dan 369
Scanga, Charles A. 667
Scaraffia, Patricia Y. 236
Scarborough, Robin 274
Schachter-Broide, Judith 394
Schaecher, Kurt E. 430, 565, 832,
863, 934
Schaefer, Brian C. 309
Schaffner, Stephen F. 162
Schaffner, Stephen J. 368
Schal, Coby 589, 889
Schantz, Peter M. 101, 134
Schiehser, Guy A. 173, 174, 505
Schillinger, Anne-Sophie 234
Schimmenti, Lisa A. 695
Schlarman, Maggie S. 493, 861
Schlesinger, Jacob J. 3, 457
Schmaedick, Mark A. 890
Schmaljohn, Connie S. 612
Schnabel, David 619
Schneider, Andre 1070
Schneider, Henning 803
Schneider, Petra 846
Schneider, Toni 1031
Schneider, Timothy G. 366
Schofield, Christopher J. 400
Schofield, Louis 301
Schönian, Gabriele 864
Schuller, Elisabeth 687
Schwartzman, Kevin 383
Schwenk, Robert J. 319
Schwenkenbecher, Jan M. 988
Scopel, Kézia K. 697
Scott, James 328
Scott, Mathews 624
Scott, Robert M. 429
Scott, Thomas W. 264
Scovill, John 102
Se, Youry 934
Seck, Yacine 831
Secor, W. Evan 307, 310, 664
Sedegah, Martha 11, 304, 581
Sedyaningsih, Endang 681
Seear, Michael 90
Seethamchai, Sunee 542, 545
Segeja, Method D. 842
Segovia, Rosana 328
Seiber, Eric 543
Seitz, Amy E. 786
Sejvar, James J. 1041
Self, Joshua S. 614
Sellers, Morgan 870
Sembuche, Samwel H. 842
Semnani, Roshanak 665
Senthong, Wichai 428
Sept, David 1002
Sepulveda Toepfer, Jorge A. 629
Sere, Yves 423
Serpa, Jose A. 32
Serra-Casas, Elisa 306
Serrano, Adelfa E. 836
Serwadda, David 96
Seth, Misago 842
Setha, To 897
Seto, Edmund 675
Severson, David W. 239, 873, 874
Sevilleja, Jesus Emmanuel A. D. 745,
751
Sewell, Charles M. 663
Seydel, Karl 1053
Shaffer, Donna 213
Shahan, David N. 276
Shaheen, Hind I. 905, 906
Shaikh, Gulvahid 907
Shang, Chuin-Shee 105
Shanks, G. Dennis 42, 173, 174,
187
Shapiro, Theresa A. 653
Sharakhov, Igor V. 869, 1028
Sharakhova, Maria V. 869, 1028
Sharar, Kristin L. 7
Shardell, Michelle 731
Shareef, Mohammed O. 907
Sharif, S. K. 546
Sharma, Navneet 432
Sharma, Yagya D. 201, 528, 877
Shaw, Alexandra 794
Shea-Donohue, Terez 983
Sheff, Kelly 330, 331, 908
Shepard, Donald S. 27, 28, 118,
350, 764
Sher, Alan 964
Sherchand, Jeevan B. 789
Shi, Pei-Yong 661
Shi, Weibin 753
Shiff, Clive J. 896, 938
Shililu, Josephat I. 248
Shimp, Jr., Richard L. 576
Shin, Dongyoung 239
Shin, Eun-Hee 567, 608
Shin, Mi-Young 157
Shipton, Warren 713
Shoemaker, Charles B. 333, 629
Shoemaker, David 379
Shoemaker, Ritchie C. 417, 418,
419
Shokoples, Sandra E. 815
Shott, Joseph 44, 96
Shouche, Yogesh S. 869
Showalter, Melissa 630
Shresta, Sujan 7, 762
Shrestha, Mrigendra P. 429
Shrestha, Sanjaya K. 429
Shrivastava, Sandeep K. 521
Shukla, M. M. 201
Shusko, Michael 415
Shustov, Alexandr V. 658
Si, Yuanzheng 168
Siba, Peter 1007
Sibley, Carol H. 173, 174, 533, 827,
828
Sibley, L. David 1075
Sidibe, Bakary 421, 492, 835, 1057
Sidy, Sidy 508
Sieber, Eric 674
Sievers, Amy 734
Sigiscar, Marcel 81
Sihom, Francois 722
Sikaala, Chadwick 841
Sikalima, Jay 938
Silachamroon, U. 1006
Silengo, Shawn J. 1, 114, 471
Sillman, Marla 8, 572
Siludjai, Duangkamon 430
Silumbe, Kafula 844
Silva, Breno M. 450
Silva, Claudia J. 727
Silva, Natal S. 697
Silva, Sheyla 25
Sim, Cheolho 233
Sim, Kim Lee 216
Simard, Frédéric 38, 865, 872,
1027, 1035
229
Simmons, Cameron 22
Simmons, Kaneatra J. 154, 648
Simmons, Monika 115, 346
Simoes, Mariana 286
Simon, Markus 949
Sims, Jennifer S. 1013
Sims, Peter A. 1013
Sinagra, Angel 89
Singer, Burton H. 851
Singh, Balwan 806
Singh, Mrigendra P. 182, 183, 341,
535, 1055
Singh, Neeru 182, 183, 194, 201,
341, 528, 535, 1055
Singh, Naresh 251
Singh, Paramjit 432
Singh, Puspendra P. 182, 341
Singh, Upinder 1048
Sinha, Prabhat K. 85
Sinishtaj, Sandra 653
Sinnis, Photini 505
Sipilanyambe, Nawa 569
Siqueira, Isadora 283
Siqueira, João B. 28, 764
Siribie, Aboubacar 709
Siriyanonda, Duangsuda 618
Sirois, Patricia 473
Sissako, Aliou 508, 510, 856
Sissoko, Ibrahim M. 868
Sissoko, Sibiry 712
Sitdhirasd, Anussorn 330
Sitdhirasdr, Anussorn 331, 908
Siu, Edwin 187
Skarbinski, Jacek 21, 338, 339, 351
Skelly, Patrick J. 333, 629
Skinner-Adams, Tina S. 165, 500
Skowren, Gail 1045
Slatko, Barton 782
Slemenda, Susan B. 810
Slotman, Michel A. 872
Slutsker, Laurence 338, 339, 351,
546, 546
Slutsker, Laurence 175
Small, Jennifer 989
Smilkstein, Martin 822
Smith, Alan 983
Smith, Adrian D. 356
Smith, Bryan 934
Smith, Craig S. 954
Smith, Derek 483
Smith, David 805
Smith, David L. 532
Smith, Jan 771
Smith, Joe D. 49, 580
Smith, Kirsten 168
Smith, Kristin E. 942
Smith, Martin 1068
Smith, Thomas A. 671
Smith, Valerie 356
Smoak, Bonnie L. 332, 618
Author Index
Snavely, Jeffrey D. 1015
Snow, Robert W. 339
Soares, Irene S. 697
Sobhon, Prasert 783
Soblik, Hanns 985
Sobry, Agnes 722
Sobsey, Mark D. 53, 54, 56
Socheat, Doung 350, 897, 934,
1004
Sodahlon, Yao K. 720
Soisson, Lorraine 11, 12, 48, 219,
304, 581
Sokhna, Cheikh A. 214
Solano, Maria Gabriela 136
Solano, Mayra E. 894
Solomon, Tom 1042
Solorzano, Nelson 738, 898, 1046
Somboon, Pradhya 232
Song, Jin-Won 958
Songprakhon, Pucharee 2
Sonmez, Gulden 791
Soong, Lynn 668
Soremekun, Seyi 792
Sorgi, Carlos A. S.. 137
Sosa, Iris 754
Sosa-Estani, Sergio 787
Soto, Giselle 680, 728
Soto, Jaime 1001
Soumaoro, Lamine 952
Soumbey-Alley, Edoh William 772
Sousa, Anastacio Q. 479, 1047
Sousa, Taís N. 570
Souza, Daniela I. S.. 137
Souza, Estéfano A. 697
Sow, Samba O. 326, 382, 384, 740,
917
Sowunmi, Akintunde 88, 524, 527,
651
Specht, Sabine 389
Speicher, James 124
Spicher, Martin 75, 376
Spielman, Andrew 244, 690, 891,
1045
Spillmann, Cynthia 392
Spithill, Terry W. 36, 166
Spranger, Stefani 288
Spray, David C. 805
Spring, Michele D. 220, 556
Srikiatkhachorn, Anon 453, 763
Srivastava, A. 617
Sriwichai, Sabaithip 934
St-Jean, Miguel 1075
Staedke, Sarah G. 340, 343, 352
Staerk, Katharina 97
Stahle, David W. 732
Staley, John 187
Stanisic, Danielle I. 159, 301, 551,
552
Stanuszek, William W. 599
Stapleton, Jack T. 313
Starnes, G. Lucas 1075
Starzengruber, Peter 636
Stauber, Christine E. 54
Stav, Gil 1034
Stayback, Gwen 64, 395
Stedman, Timothy 209
Steel, Cathy 950
Steen, Hanno 985
Steinauer, Michelle L. 336
Steinbeiss, Victoria 11
Steindel, Mario 997
Steiner, Kevin 153
Steketee, Richard W. 543, 671, 674,
844
Sterling, Charles 266
Steurer, Frank J. 786
Stewart, V. Ann 44, 218
Stiasny, Karin 687
Stiles, Jonathan K. 147, 194, 804,
1055
Stiles-Ocran, Joseph B. 596
Stinchcomb, Dan T. 114, 471
Stolk, Wilma A. 359, 676
Stoltzfus, Rebecca J. 180
Stoney, Jillian R. 501
Storlie, Patricia A. 144
Stout, Barbara A. 285
Stout, John 982
Stoute, José A. 189, 219
Stracener, Catherine N. 189
Stramer, Susan 348
Street, Ian 554
Strickland, G. Thomas 731
Stripen, Boris 1069
Strode, Clare 621
Strohbusch, Maria 963
Stromdahl, Ellen Y. 435, 1065
Stubbs, Jose 612
Stuedli, Angela 605
Sturtevant, Joy 140
Styer, Linda M. 659
Su, Xinzhuan 209
Suarez, David L. 994
Suarez-Ognio, Luis A. 104, 728,
738, 1046
Suaya, Jose A. 27, 28, 118, 350,
764
Suazo, Harold 645
Subhadra, Bobban 624
Subrahmanyam, Sreenath 396
Subramanian, Ramanand A. 945
Suchman, Erica L. 625
Sughayyar, Rana 28, 764
Sugiarto, P 354, 701
Suguitan, Amorsolo 559
Sujariyakul, Anupong 784
Sukhbaatar, Munkhzul 23
Sukprasert, Walailuk 107
Suktawonjaroenpon, Wachira 515
Sukthana, Yaowalark 604
Sulaiman, Irshad M. 274
Sulaiman, Nikhat 274
Sullivan, Andrew K. 316
Sullivan, David J. 961
Sultan, Ali A. 163
Sultana, Rebeca 281
Sumba, Peter O. 556, 557
Sumibcay, Laarni 958
Sumiwi, Maria E. 736
Sun, Jianxin 62
Sun, Jian 825
Sun, Peifang 115
Sun, Peter 488
Sun, Tao 71
Sun, Wellington 346
Sun, Yanjie 923
Sundar, Shyam 378
Sunderland, Deirdre 962
Supali, Taniawati 785
Surachetpong, Win 251
Surasri, Sittidech 934
Suri, Vikas 432
Susanti, Augustina I. 76
Suswillo, Richard R. 133
Sutherland, Colin 578
Sutthirattana, Saithip 330, 331, 908
Sutton, Patrick L. 850
Suwannachote, Nantawan 586
Suwonkerd, Wannapa 586
Suzuki, Stephanie 533
Svensson, M. 1071
Swa, Tidjane 496
Swaby, James 444
Swalm, Christopher 259
Swan, Ken 473
Swayne, David 994
Swierczewski, Brett E. 295
Sygusch, Jurgen 1075
Sylla, Mariam 326, 712, 740
Sztein, Marcelo B. 324
Szumlas, Daniel E. 61
T
Tabouret, Marc 442, 443
Tachibana, Mayumi 575
Tadesse, Eyob 693
Tahita, Marc Christian 682
Tajima, Shigeru 686
Takahashi, Paula 761
Takala, Shannon L. 14, 530, 969
Takasaki, Tomohiko 686
Takeo, Satoru 484, 574
Talaat, Kawsar R. 390, 667
Tall, Adama 214
Tall, Kouressi 409
Tam, Doan Thi Minh 456
Tamami, Matsumoto 89
Tamang, Leena 962
Tamarozzi, Francesca 72
230
Tamayo, Pablo 369
Tamboura, Boubou 740, 917
Tamminga, Cindy 115
Tan, Asako 160
Tanabe, Kazuyuki 564
Tang, Guanhong 236
Tang, Kevin 274
Tangpukdee, N 519
Tangpukdee, Noppadon 811
Tangpukdee, Noppadom 1006
Tanner, Marcel 41, 227, 261, 729,
845, 848, 851
Tanowitz, Herbert B. 146, 805
Tanyuksel, Mehmet 431
Tapia, Milagritos D. 326, 382, 384,
740, 917
Tapiero, Bruce 383
Tapley, Erin C. 561
Tappe, Dennis 375
Taquri, Carmen 31
Taraika, Jack 301
Taranto, Néstor 89
Taraschi, Theodore F. 366, 531
Tarazona-Santos, Eduardo 570
Tardif, S. D. 278
Tariq, Parveen 678
Tarleton, Rick L. 1072, 669
Tarnagda, Zekiba 682, 709
Tasca, Karen I. 482
Tatay, Mercedes 725
Tate, Jacqueline 15
Tatto, Erica 997
Tauber, Erich 122, 687
Taylor, Charles E. 868
Taylor, Dennis 654
Taylor, Diane Wallace 425, 559
Taylor, Ronald P. 199, 323
Taylor, Terrie E. 530, 834, 969,
1021, 1053
Taylor, Walter 506, 634, 1006
Tazir, Yasmina 985
Tchinda, Viviane H. M. 425
Teale, Judy M. 34
Teixeira, Andrea 291
Teixeira, Clarissa R. 69, 391, 981,
1039, 1052
Teja-Isavadharm, Paktiya 934
Teklehaimanot, Awash 698
Tekwani, Babu L. 862
Telford, Sam 50, 901, 1045, 1062,
1063
Tellez, Luis 271
Tellez, Yolanda 25
Temu, Emmanuel A. 57
Tenjo, Fernando 440
Tenorio, Michely S. 482
Teodoro, Tatiana M. 294
ter Kuile, Feiko O. 341, 497, 971
Terlouw, Dianne J. 341, 497, 971
Terp, Sophia 439
Author Index
Terpinski, Jacek 173, 174
Tesh, Robert B. 691
Tetteh, John K. 195, 198
Tetteh, Kevin 302
Teyssou, Rémy 449
Thaisomboonsuk, Butsaya 765, 767
Thalhofer, Colin J. 314
Thamthitiwat, Somsak 329, 911,
915
Thang, Cao Minh 456
Thang, Carole 716
Thangamani, Saravanan 247
Thanh, Nguyen X. 94
Thao, Thi Thu 1042
Thapa, Gyan B. 429
Thavrin, Bou Kheng T. Thavrin.
Thavrin. 80
The, Nguyen D. 94
Thea, Donald M. 678
Theander, Thor G. 843
Theisen, Michael 192
Thera, Mahamadou A. 14, 1058
Therrell, Matthew D. 732
Thesing, Phillip C. 834
Thevenon, Audrey D. 559
Thomas, Elizabeth 369
Thomas, Peter 181, 540
Thomas, Stephen 765
Thompson, Anthony 651
Thompson, Eloise 499
Thompson, Katy-Anne 499
Thompson, Winston 147
Thonnard, Joelle 8
Thorat, Swati 801
Thorp, John 703
Thorson, Kelsey 976
Thriemer, Kamala 636
Thuma, Philip E. 229, 677, 896,
838, 938
Thumar, Bhavin 347
Thuy, Le T. T. 94
Thwing, Julie I. 223
Tiamkao, Somsak 428
Ticona, Carlos 898
Tidwell, Richard R. 816
Tielsch, James 180
Tien, Nguyen Thi Kim 443
Tigray Malaria Study Group (G.
Barnabas, A. Bianchi, A. Bosman, P.
Byass, G. Constanzo, P. Ibarra de
Palacios, N. Jude, A. Morrone, L.
Toma, Ethiopia) 718
Tiinto, Halidou 833
Tilley, Leann 654
Timmann, Christian 785
Tinelli, Carmine 72
Tiono, Alfred 651
Tipayamongkholgul, Mathuros 769
Tippayachai, Bousaraporn 515
Tisch, Daniel J. 358, 556
Tjaden, Jeffrey 115
Tjitra, Emiliana 354, 486, 544, 701,
1004
Tkach, Vasyl V. 880
Tobing, Charles 736
Tobler, Leslie H. 996
Tocheva, Anna 293, 311
Togo, Amadou 421, 492
Togo, Pierre 712
Tokumasu, Fuyuki 487, 588
Toledo, Ampara 627
Toledo, J. 1001
Toliat, Mohamad Reza 388
Tomashek, Kay M. 112, 348
Tomaszewski, Konrad 517
Tomova, Cveta 1069
Tong, Carlos 866
Tongren, Jon Eric 194, 1055
Tonnetti, Laura 606
Tontonoz, Peter 150
Torii, Motomi 208, 574, 575
Torrero, Marina N. 775, 948
Torres, Katherine 206
Torres, Pedro 826
Torres-Jiménez, Fernando 78
Torres-Slimming, Paola A. 19
Toure, Abdoulaye 1057
Toure, Mahamoudou B. 868
Toure, Sekou 421, 492, 835, 1057
Toussaint, Jean Francois 765
Tovar, Marco 680
Toxeira, Clarissa 396
Toz, Seray O. 148, 791
Tozan, Yesim 224, 534
Trampe, Ranferi 403
Tran, Thi Thuy 22
Tran, T.H. 207
Tran, Thu A. 150, 631
Tran, Thanh N. 165
Tran Nguyen, Bich Chau 22
Traore, Aminata 717
Traore, Cheick 952
Traore, Karim 14
Traore, Kalirou 712
Traore, Pierre 409, 710
Traore, Seydou 712
Traore, S. Cheick 1022
Traore, Sekou F. 868
Travers, Thomas 94
Trindade, Giliane 991
Tripathi, N.K. 617
Tripathi, Vinita 395
Trongnipatt, Namtip 515
Trongtorkit, Yuwadee 232
Tropel, David 45
Trostle, James 328
Trouern-Trend, Jonathan 795
Troye-Blomberg, Marita 193
Troyes, Lucinda 738, 1046
Troyes, Mario 898
Troyo, Adriana 894
Trueba, Gabriel 328
Trung, Dinh T. 452
Tsang, Victor C. 30, 31
Tsao, Jean 1060
Tschannen, Andres B. 729
Tsetsarkin, Konstantin A. 613, 658,
730
Tshefu, Antoinette 703
Tsuboi, Takafumi 208, 484, 574,
575
Tsuji, Moriya 805
Tsujimoto, Hitoshi 393
Tsukayama, Pablo 475
Tsvetkova, Albina 129
Tu, Zhijian 869, 871
Tuchman, Jordan 535
Tucker, Compton J. 989
Tuiten, Wieteke 66
Tumer, Derya 900
Tumwine, James K. 426
Turato, Walter M. T.. 137
Turell, Michael J. 125, 598, 880
Turnbull, Lindsey 1053
Tyo, Karen 28, 764
Tzec-Arjona, Juan L. 151, 152
Tzipori, Saul 426
U
Ubalee, Ratawan 515
Udhayakumar, Venkatachalam 194,
341, 535, 971, 972, 1055
Udomsangpetch, Rachanee 515
Ueta, Marlene T. U.. 137
Ulloa-Martínez, Marcela 188
Umaru, John 422
Umeh, Rich 651
Ungchusak, Kumnuan 911, 960
Unger, Alon 380
Unnasch, Thomas R. 363, 781, 875,
880, 926
Urban, Joseph 983
Urdaneta-Marquez, Ludmel 867,
1038
Usera, Aimee 653
Uthaipibull, Chairat 193
Utzinger, Jürg 246, 729
Uzun, Ozcan 431
V
Vahdat, Katayoun 743, 919
Vaidya, Akhil B. 365, 855, 857, 858,
859
Vaillant, Michel 378, 506, 634,
1006
Valda, L 1001
Valderamma, Carlos 886
231
Valderramos, Juan-Carlos 505, 940
Valderramos, Stephanie 940
Valdez-Padilla, David 270
Valenzuela, Jesus 64, 395, 397
Valenzuela, Jesus G. 69, 391, 396,
981, 1039, 1052, 1061
Valiente-Banuet, Leopoldo 996
Vaillant, M. 1005
van Buuren, Stef 497
van de Pol, Corina 520
Van den Broek, Ingrid 974
van den Eng, Jodi 736
van Dijk, Janneke 677
van Dooren, Giel 1069
Van Dyke, Melissa K. 699
Van geertruyden, Jean-Pierre 937
Van Herp, Michel 974
Vanden Eng, Jodi 223, 464, 546
Vanderberg, Jerome 37, 156
VanEkeris, Leslie A. 942
VanKirk, Nicole 55
Vanlandingham, Dana L. 613, 658,
730
Vannier, Edouard 1045
Varghese, George M. 719
Varma, Subhash 432
Vasconcelos, Helena B. 755
Vasconcelos, Pedro F. C. 123, 131,
755
Vasquez, Rene E. 668
Vasquez, Yessika 40
Vaughan, Jefferson A. 880, 883
Vaughn, David 763
Vaughn, David W. 102, 453
Vazquez Prokopec, Gonzalo M. 392
Veazey, James 520
Veenstra, Timothy D. 665
Veerman, Lennert J. 359
Vekemans, Johan 10, 572
Veland, Nicolás 475
Velasco, John Mark S. 760
Velasco de Castro Oliveira, Juliana
466, 689
Velasco-Villa, A. 957
Velázquez-Márquez, Liliana 273
Velazquez-Martínez, Israel 269
Velez, Juan Diego 43
Velez, Jason O. 128
Vello, Marianne 59
Vemuri, R 544
Venegas, Fay 844
Venkatesan, Meera 870, 878
Ventura, Gladys 738
Verani, Jennifer R. 720
Verastegui, Manuela R. 29, 35
Vergne, Edgardo 756
Verhave, Jan Peter 846
Verma, Rakesh B. 85
Verma, Saguna 460
Verma, S.K. 617
Author Index
Vernick, Kenneth D. 876
Verrey, François 333
Verter, Joel 379
Vestergaard, Lasse S. 843
Victor, Bjorn 33
Vidal, Carlos E. 850
Vidal, Jaume 826
Vieira, Carlos M. G.. 745
Viera, Juan-Carlos 387
Viera, Sara 512, 513
Vilcheze, Catherine 505
Villacis, Anita G. 400
Villacorte, Elena A. 564
Villafana, Tonya 10
Villalta, Fernando 154, 648
Villanueva Diaz, Jose 732
Villard, Claude 238
Villaseca, Pablo 884
Villegas, Zoila 738, 1046
Villinski, Jeffrey T. 61
Vinayak, Sumiti 528
Vince, Mary 435
Vinetz, Joseph M. 370, 484, 541,
866
Visconti, Sabato 1014
Vissa, Vara 78
Viveiros, Rita de C. S.. 482
Viviani, Simonetta 384
Vogt, Richard G. 600
Volf, Peter 391
Volkman, Sarah K. 162, 204, 368,
579, 1021
Volpe, Katharine E. 1
von Glasenapp, Isabelle 10
von Schubert, Conrad 1076
von Sonnenburg, Frank 122
Vong, Sirenda 26
Vossen, Matthias 636
Vounatsou, Penelope 729
Vourc’h, Gwenael 1060
Vu, T.H. 207
Vu, Thi Que Huong 451, 454
Vuchev, Dimitar 373
Vuitton, Dominique A. 71
Vulule, John 15, 20, 200, 321, 546,
548, 549, 587, 595, 694, 707, 814,
853, 1036, 1056
W
Wacker, Mark A. 160
Wada, Marcelo Y. 997
Wadsworth, Mariha 64, 395
Wagner, Karen 772
Wain, John 741
Waite, Erica 296
Waitumbi, John N. 199, 215, 219,
323, 578, 1016
Walker, Edward D. 587, 595, 599,
1036
Walker, Jeffrey B. 76
Walker, Larry A. 862
Wallace, James 186
Waller, Lance A. 627, 786
Walls, Colleen D. 967
Walsh, Doug 735
Walter, Nicholas 21
Walter Reed Clinical Leishmaniasis
Group 379
Walther, Michael 197, 210, 696,
812
Walton, Shelley 433
Wamachi, Alex 153
Wamulume, Pauline 355, 543
Wang, Danher 345
Wang, Eryu 927
Wang, Guangze 970
Wang, Hua 279
Wang, Heuy-Ching 610
Wang, Hui 1066
Wang, Shanqing 970
Wangrungsarb, Piyada 911
Wanionek, Kimberli 347
Ward, Honorine D. 609
Ward, Jerrold
Ward, Jerrold M. 396, 1017, 1061
Ward, Michelle 346
Ward, Steve A. 1003
Ware, Lisa A. 218
Waree, Phuangphet 604
Warikar, N. M. 354, 701
Warke, Rajas 24
Warner, Jeffrey 713
Warren, Ben 1023
Warren, Cirle A. 745
Wartel-Tram, Anh 344
Watany, Noha 61
Waterman, Stephen 110, 469
Waters, Norman C. 656, 817, 820
Watila, Ismaila 651
Watts, Douglas M. 615
Wawer, Maria J. 96
Weatherall, David J. 207, 1059
Weaver, Scott C. 278, 615, 927,
928
Webster, Francis X. 68
Weigand, Roger 821
Weil, Gary J. 360, 361, 362, 777,
779, 1014
Weina, Peter J. 167, 168, 169, 170,
318, 415, 480, 1009
Weinberg, Brice 486
Weiner, Mathew 905, 906
Weiss, Louis M. 146
Weiss, Walter 581
Welch, David 349
Wells, Michael A. 235, 236
Wendel, Clifford E. 618
Wenink, Emily 811
Werbovetz, Karl 1002
Were, Tom 20, 200, 321, 353, 548,
549, 694, 707, 1056
Wesson, Dawn W. 130, 186, 259,
473, 886, 889, 1034
Westbrook, Catherine J. 582
Weverling, Gerrit-Jan 44
Wheeler, Sarah 459
White, A. Clinton 32, 610, 986
White, Gregory S. 926
White, Nicholas J. 936, 1042
White, Sandy 390, 667
Whitehead, Stephen S. 124, 347
Whitehouse, Chris 125
Whittle, Hilton 302
Whitty, Christopher J. M. 343, 356
Wichmann, Ole 725
Wickramarachchi, Thilan A. 566
Widdowson, Marc-Alain 15, 439
Widyastuti, Endang 736
Wiegand, Roger C. 162, 204, 368,
652
Wiggan, O’Neil 114, 471
Wikel, Stephen K. 62, 247
Wilairatama, P 1006
Wilder, Tuere 311
Wilkerson, Richard C. 881, 882
Will, Roeffen 846
Williams, Frank 11, 216, 304
Williams, Gail M. 71, 290, 1051
Williams, Janice 292
Williams, Jackie 319
Williams, Jeffrey F. 55
Williams, Steven A. 136, 781, 1014
Williams, Tom 300
Williams, Thomas 554
Williamson, Kim C. 518
Willis, Steven G. 594
Wills, Bridget 452
Wilson, Alan 296
Wilson, Danny 551
Wilson, Ian J. 336
Wilson, Leslie S. 996
Wilson, Marianna 101
Wilson, Michael D. 211, 596
Wilson, Mary E. 144, 313, 314, 630
Wilson, Mark L. 599, 699, 999
Wilson, Nana 147, 804, 1055
Wilson, Ron 260
Winstanley, Peter A. 1003
Winter, Rolf 822
Winters, Anna M. 888
Winzeler, Elizabeth 369
Wirth, Dyann F. 162, 204, 368, 489,
524, 527, 579, 652, 821, 824, 935,
1013, 1021
Wise de Valdez, Megan R. 625
Witzig, R. 416
Wlazlo, Anthony 124
232
Woehlbier, Ute 194
Wohlhueter, Robert 274
Wojick, Richard 104
Wölfel, Roman 463, 904
Wolff, Brian 292
Wolkon, Adam 546
Won, Kimberly 101, 134
Wong, Joseph 705
Wongjindanon, Wanna 327, 329,
915
Wontuo, Peter 439
Woodard, Lauren 653
Wootton, Dan 1003
Woraratanadharm, Jan 345
Wormser, Gary 1045
Wortmann, Glenn 379, 395
Wu, Bo 782
Wu, Hai-Wei 70
Wu, Haiwei 335
Wu, Shuenn-Jue 115, 444
Wu, Wenjie 1032
Wu, Xiao-Jun 298
Wylie, Blair J. 535
Wynn, Thomas A. 309
Wypij, David 369
Wysocki, Vicki H. 236
X
Xayavong, Maniphet 810
Xi, Zhiyong 640
Xia, Ai 869, 1028
Xiao, Shu-Yuan 691
Xie, Lisa 167, 169, 170
Xiong, Tie 1051
Xiong, Xu 473
Xu, Jin-Mei 70
Xu, Zhi-yi 26
Xue, Gongda 1076
Y
Yabsley, Michael J. 59, 998
Yanagi, Tetsuo 789
Yanagihara, Richard 468, 958
Yancey, Linda S. 610
Yang, Hae-Won 267
Yang, Yu R. 71
Yano, Kazuhiko 208
Yanoviak, Stephen 623
Yanow, Stephanie K. 36, 166, 815
Yao, Chaoqun 144
Yaremych-Hamer, Sarah 1060
Yaro, Alpha S 1022
Yasmin, Tabassum 907
Yates, John R. 370
Yates, Terry L. 958
Yauch, Lauren E. 7, 762
Author Index
Yazdani, Syed S. 191, 222
Ye-Ebiyo, Yemane 891
Yeboah-Antwi, Kojo 535
Yee, Eileen 15
Yen, Nguyen T. 644
Yeo, Tsin 486
Yeom, Joon-Sup 157
Yépez-Mulia, Lilián 269, 270, 271,
272, 273
Yeung, Shunmay 936
Yiadom, Boakye 637
Yimamnuaychok, Nongnuch 515
Yin, Yong 779
Yingst, Sam 925
Ylla-Velasquez, Jose 627
Yong, Yin 362
Yongvanitchit, Kosol 218
Yoo, Ji-Ae 157
Yoo, Won Gi 284
Yoon, In-Kyu 113, 760
Yori, Pablo P. 541
Yosaatmadja, Francisca 693
Yoshino, Timothy P. 298, 1030
Yougbare, Issaka 682, 709
Young, Mary 1045
Young, Steve 663
Yourick, Debra 502
Youssef, Fouad G. Y. 918
Ypil-Butac, Charity A. 760
Yu, Min 505
Yu, Xinling 1051
Yuesheng, Li 1051
Yumiseva, Cesar A. 400
Yurchenko, Vyascheslav 146
Yusuf, Bidemi 404
Yuwono, Djoko 766
Zheng, Feng 1051
Zheng, Hong 1017
Zhou, Ainong 425, 559
Zhou, Hong 13, 47, 48
Zhou, J. 1051
Zhou, Yingyao 369
Zhou, Zhiyong 971, 972
Zhu, Daming 213, 573
Zhu, Jianzhong 1020
Zhu, Liqun 367
Ziegler, Rolf 976
Ziegler, Sarah A. 691
Zijlstra, Edward 1003
Zimmerman, Peter A. 159, 181,
540, 695, 699, 809, 814
Zimmerman, Robert H. 883
Zinyowera, Sekesai 325
Zollner, Gabriela 185, 401
Zongo, Issaka 423, 424, 833
Zou, Xiaoyan 217
Zúniga, Concepción 787
Zurovac, Dejan 339, 351
Zwang, Julien 1005
Z
Zaidenberg, Mario 392, 398
Zaks, Laurel 16
Zamalloa, H. 957
Zambrano, Betzana 344
Zamora, Jorge 976
Zanotto, Pablo M. de A 466, 689
Zborowski, Maciej 809
Zea-Flores, Guillermo 387
Zeba, Augustin N. 709
Zeccer, Suzana 997
Zeng, Qiang 168
Zhang, Jing 167, 169, 170
Zhang, Luhua 116
Zhang, Lixin 328
Zhang, Mengzi 298
Zhang, Qiong 739
Zhang, Si-Ming 285
Zhang, Shuliu 660
Zhang, Wei 71
Zhang, Xuebin 825
Zhang, Yanling 576
233
Speaker and Session Chair Index for Plenary, Symposium, Meet the Professors and Mid-Day Sessions
Important Note: The number(s) following name refers to the session number.
A
Abdulla, Salim 2A, 148
Abraham, David 125
Adegbola, Richard 117
Adelman, Zach 94
Ahouidi, Ambroise 162
Allen, Judith 92
Allweiss, Pamela 28
Alonso, Pedro 117
Aly, Ahmed 67
Anderson, Tim 141
Andrade-Narvaez, Fernando 13
Andrews, Norma 16
Arevalo-Herrera, Myriam 23
Arguin, Paul 82, 95
Arnold, Keith 106
Aronson, Naomi 56
Arthur, Ray 50
Awolola, Taiwo 154
B
Baggett, Kip 112
Bailey, Robin 38
Ballou, Ripley 148
Baluk, Peter 83
Baniecki, Mary Lynn 101, 111
Bargues, M. 48
Barik, Sailen 55
Barillas-Mury, Carolina 22
Barrett, Alan 139
Barry, Michele 29, 60
Bathurst, Ian 49
Beck, Hans-Peter 93
Belkaid, Yasmine 64
Bell, David 33, 75
Bergman, Lawrence 132
Bernhardt, Scott 94
Berriman, Matthew 14
Beverley, Stephen 16, 34
Bia, Frank Plenary Session I
Binka, Fred 19
Blair, Carol 70
Blazes, David 50
Blumenthal, Denise 131
Bojang, Kalifa 114
Bolinsky, David 131
Bosch, Irene 18, 131
Boulware, David 27, 138A
Boyle, Jon 5
Brandling-Bennett, David 41
Brandly, Eugene 65
Brault, Aaron 108
Breiman, Robert 112, 117, 135,
145
Brombacher, Frank 92
Brooks, W. Abdullah 115
Brooks, Alan 148
Brun, Reto 111
Brunetti, Enrico 9
Buckner, Frederick 37
Budke, Christine 9
Buguet, Alain 119
Burri, Christian 85
Burton, Matthew 38
Büscher, Philippe 56
C
Caffrey, Conor 123
Cahill, John 8
Calisher, Charles 1
Campbell, Carlos C. (Kent) Plenary
Session I, 29, 41, Plenary Session III,
Plenary Session IV
Carabin, Hélène 9
Carneiro, Ilona 126
Carucci, Daniel Plenary Session I
Carvalho, Edgar 61
Cerrell, Joe 10
Champagne, Donald 140
Charman, Susan 49
Checkley, Anna 62
Chen, Lin 138A
Cheng, Qin 17, 147
Chiodini, Peter 33
Chitnis, Nakul 80
Chizema, Elizabeth 41, 100
Cisse, Badara 114
Clark, Robert 19
Clarke, Sian 114
Cline, Barnett 60, 132A
Cohen, Joe 148
Coleman, Michael 3
Colley, Daniel 42
Coll-Seck, Awa 41, Plenary Session
III
Conn, Jan 168
Conner, Stephen 58
Costero, Adriana 36
Craft, Noah 79
Craig, Alister 87
Croft, Simon 111
Cross, George 34
D
da Silva-Nunes, Mônica 122
D’Alessandro, Umberto 2A, 69
Davies, Stephen 42
de Castro, Marcia 172
de Sousa, Alexandra 126
Debboun, Mustapha 40
Dematteis, Sylvia 98
Desai, Sanjai 49
Desjeux, Phillipe 113
Diabate, Abdoulaye 163
Diallo, Dapa 170
Diamond, Michael 70
Dicko, Alassane 97, 114
Dillon, Rod 90
Dimopoulos, George 77
Diuk-Wasser, Maria 171
Djimde, Abdoulaye 93, 170
Doannio, Julien 154
Docampo, Roberto 55
Dodoo, Alexander 19, 69
Donelson, John 34
Dorsey, Grant 93
Doumbo, Ogobara 97
Dowdy, David 43
Doyle, Patricia 37
Dumler, J. Stephen 15
Dunavan, Patrick 132A
Durbin, Anna 57
Dutra, Walderez 44
Gottlieb, Michael 40
Gottstein, Bruno 73, 98
Gotuzzo, Eduardo 125
Gould, Hannah 135
Graczyk, Thaddeus 146
Green, Michael 116
Greenaway, Christina 27, 159
Greenwood, Brian 114
Grobusch, Martin 126
Gubler, Duane 36, 107
Gutteridge, Win 49, 79A
E
Haag, Karen 98
Hailemariam, Afework 41
Hajduk, Stephen 16
Haldar, Kasturi 55, 127
Halstead, Scott 102
Hamer, Davidson Late Breakers in
Clinical Tropical Medicine, 128
Hanson, Kara 65
Haq, Cynthia 60
Harn, Donald 92, 169
Harnett, William 99
Harrington, Laura 79
Hartman, Amy 70
Haynes, John 58
Haynes, Richard 106
Heise, Mark 70
Heisler, Michael 60
Hemphill, Andrew 98
Hendricks, Joan 107
Hentschel, Christopher 2A, 100
Herwaldt, Barbara Late Breakers in
Higgins, James 131
Higgs, Stephen Plenary Session I,
79
Hightower, Allen 145
Hill, Kent 34
Hills, Susan 160
Hillyer, George 48, Plenary Session
IV
Hillyer, Julian 77
Hira, Parsotam 159
Hoffman, Stephen 103
Hoffman, Risa 79, 129
Hosseinipour, Mina 118, 129
Hotez, Peter Plenary Session I, 7,
136
Houpt, Eric 64
Hugo, Leon 149
Hunter, Chris 55
Hurtado, Rocio 43
Huygen, Kris 136
Huynh, Chuong 78, 130
Egan, Andrea 126
Eisen, Lars 3
El Setouhy, Maged 63
Ellis, Amy 138
El-Sayed, Najib 151
Epstein, Paul 79A
Epstein, Jonathan 144
F
Failloux, Anna-Bella 168
Fallon, Padraic 92
Farnon, Eileen 135
Feagin, Jean 96
Fenwick, Alan 7, 66
Fernandez, Facundo 116
Fikrig, Erol 15
Fillinger, Ulrike 172
Fischer, Marc 160
Fonseca, Dina 168
Freedman, David 32A, 85
Friede, Martin 126A
G
Ganley-Leal, Lisa 109
Ganta, Roman 15
Garba, Amadou 7
Garcia, Hector 21
Gargallo, Domingo 49
Gaus, David 60
Gause, William 64, 92
Gaywee, Jariyanart 124
Geisbert, Thomas 83
Genton, Blaise 54
Gerrets, Rene 138
Getachew, Asefaw 54
Ghalib, Hashim 142
Ghedin, Elodie 24
Gibson, Gabriella 163
Gilman, Robert 43, 129
Githeko, Andrew 172
Glass, Gregory 144
Gobert, Geoffrey 141
Gorbea, Hector 79
234
H
I
Innis, Bruce 139
J
Jackson, Scott 29
Jacobs-Lorena, Marcelo 47
Jacobson, Julie 102
Jaimovich, David 133
Jeronimo, Selma 61
Jha, Tara 113
Johnson, Barbara 160
Joyce, M. Patricia 136
K
Kabatereine, Narcis 7, 66
Kachani, Malika 9
Kahn, Laura 107
Kamat, Vinay 138
Kamau, Luna 154
Kamhawi, Shaden 90
Kappe, Stefan Late Breakers in
Basic Science/Molecular Biology
Karanja, Diana 66, 119
Kaur, Harparkash 116
Kazura, James 32
Keiser, Jennifer 123
Kern, Peter 73, 98
Keystone, Jay 81
Khan, Imitiaz 158
Kiang, Richard 58
Kihara, Jimmy 66
Killeen, Gerard 105, 110, 164
King, Charles 88
King, Lonnie 107
Kitron, Uriel 3, 46
Klugman, Keith 115
Kosoy, Michael 51
Kotloff, Karen 117
Kovarik, Carrie 72
Kramer, Laura 108, 168
Krause, Peter 46, 56
Ksiazek, Thomas Plenary Session I,
135, 145, 153
Kumar, Ashwani 110
Kumar, Sanjeev 140
Kumar, Nirbhay 47, 161
Kuritsky, Joel 139
Kurtis, Jonathan 52
Kweku, Margaret 114
Kwiatkowski, Dominic 14
Kyle, Dennis 71, 111
L
Lammie, Patrick 152
Laney, Sandra 63
Lang, Jean 139
Lanzaro, Gregory 90
LaRocque, Regina 118, 129
Leahy, Michael 10
LeDuc, James Plenary Session I, 68
Lee, John 145
Leiby, David 56
Lell, Bertrand 11
Lengeler, Christian 59, 65, 80, 100
Lescano, Andres 50
Letson, Bill 139
Levine, Myron 117
Levy, Karen 25
Li, Guoqiao 106
Libel, Marlo 50
Libraty, Daniel 6
Lietman, Thomas 38
Lim, Matthew 124
Lindsay, Steve 164, 172
Linthicum, Kenneth 36, 46, 145,
155
Lok, James 150
Loukas, Alex 136
LoVerde, Philip 123, 141
Luckhart, Shirley 77
Lumsden, Joanne 45
M
Mabey, David 38
Macete, Eusebio 148
Machado, Paulo 72
Macklin, Ruth 13
MacLean, J. Dick 32A, 125
Madoff, Lawrence 50
Magill, Alan 2, 17, 95
Mahanty, Siddhartha 143
Mahr, Roger 107
Majambere, Silas 164
Makanga, Michael 2A
Mann, Barbara 146
Mannix, Frank 102
Marano, Nina 95
Marcus, Leonard 39
Margolis, Harold 139
Martin, Diana 158
Mas Coma, Santiago 48
Mather, Thomas 3
Matlashewski, Greg 142
Mbacham, Wilfred 69, 89
McCarthy, Anne 2, 27, 32A, 81,
82, 95, 133
McCollum, Andrea 147
McDowell, Mary Ann 90, 109
McGarvey, Stephen 20, 88
McGee, Charles 79
McGovern, Victoria 55, 79, 104,
118, 129
McKenzie, F. 105
McKerrow, James 37
McMahon-Pratt, Diane 158
McManus, Donald 20
Medana, Isabelle 87
Menendez, Clara 35
Mgone, Charles 19
Michel, Kristin 77
Miesfeld, Roger 149
Mileno, Maria 8
Milhous, Wilbur 127
Miller, Scott 17
Millum, Joseph 26
Milner, Danny 118, 129
Mintz, Eric 12
Miti, Simon 41
Mohrs, Markus 74
Monath, Thomas 107
Montes, Martin 125, 150
Montgomery, Susan 88
Moore, Matthew 112
Mosser, David 16
Murithi, R.M. 135
Muro, Antonio 48
Mutonga, David 135
Mwanakasale, Victor 66
Myler, Peter 151
N
Nachega, Jean 43, 128
Nahlen, Bernard 41
Nataro, James 117
Ndao, Momar 56
Ndip, Lucy 171
Newman, Robert 126
Newton, Paul 116
N’Fale, Sagnon 154
Njau, Joseph 89
Njenga, M. Kariuki 145
Nolan, Thomas 125
Norton, Scott 72
Nosten, Francois 69
Novak, Robert 164
Nunes, Márcio 153
Nutman, Thomas 99
Nwaka, Solomon 93
O
Oakley, Miranda 162
Obrist, Brigit 138
Odhiambo, Frank 126
Ogundahunsi, Olumide 154
Ogutu, Bernhards 2A
Oliveira, Guilherme 141
Olsen, Sonja 112
Ooi, Winnie 72
Ortigao, Marcelo 90
Osei-Atweneboana, Mike 76
Ottesen, Eric 152
Ouedraogo, Jean Bosco 137
Ouellette, Marc 151
P
Painter, Heather 67
Panosian, Claire Plenary Session I,
10, 79
Papadopoulou, Barbara 34
Patterson, Amy 138
235
Paul, Michael 39
Pearce, Edward 74, 165
Peeling, Rosanna 33, 119
Peñataro-Yori, Pablo 125
Perkins, Mark 33
Petersen, Christine 44
Petri, William 103
Piazza, Franco 142
Pierce, Mark 97
Pinzon, Jorge 58
Plançon-Lecadre, Aline 116
Plowe, Christopher Plenary Session
I, 14, 71, 127
Politis, Alexander 132
Pollack, Richard 36, 39
Powell, Jeffrey 47
Powers, Ann 153
Preve, Ricardo 31, 104A
Price, Ric 62, 71
Pugh, John 132
R
Rabinovich, Regina 29, 68, 103
Ramesh, Manish 143
Ramzy, Reda 152
Ranson, Hilary 154
Reed, Christie 28, 133, 138A
Reed, Steven 126A, 142
Reeder, Maurice 30
Renshaw, Melanie 29, 41
Ribeiro, Isabela 26
Richards, Frank 10
Rico-Hesse, Rebeca Plenary Session
I, Late Breakers in Basic
Science/Molecular Biology
Riley, Steven 20
Robich, Rebecca 120
Rodriguez, Ana 96
Rodriguez, Isabel 61
Roestenberg, Meta 97
Rogers, Martin John 132
Rohde, Gitte 66
Rubenstein, Arthur 107
Rubins, Kate 155
Ryan, Edward Plenary Session I, 2,
Plenary Session IV
Ryan, Peter 3
S
Sabeti, Pardis 5
Sack, David Plenary Session II
Sajan, Nayomi 8
Salgame, Padmini 99
Salmón-Mulanovich, Gabriela 50
Salvo, Calogero 131
Sam-Agudu, Nadia 29, 121
Sang, Rosemary 135
Sasi, Philip 2A
Saul, Allan 126A
Savarese, Barbara 148
Sayed, Ahmed 123
Schantz, Peter 39
Schofield, Steve 82
Schwabe, Chris 65
Schwartz, Eli 17
Scott, Phillip 74
Scott, Thomas 105
Secor, W. Evan 165
Sedegah, Martha 35
Seder, Robert 126A
Selkirk, Murray 5
Shah, Seema 26
Sharp, Trueman 124
Shililu, Josephat 164
Shoemaker, Charles 86
Shresta, Sujan 6
Sibley, Carol 71
Siegel, Cathi 32
Silberner, Joanne 10
Simmons, Cameron 18
Sina, Barbara 118
Sinden, Robert 47
Singh, Upinder 169
Sinha, Prabhat 113
Skarbinski, Jacek 59
Skelly, Patrick 52
Slatko, Barton 24
Smith, Thomas 80
Smith, David 105
Smith, Darci 168
Sobsey, Mark 25
Solomon, Tom 120, 160, 167
Song, Jianping 106
Sousa, Anastacio 167
Sow, Samba 51, 117
Spear, Robert 20
Spithill, Terry 48
Spring, Michele 97
Srikiatkhachorn, Anon 83
Stager, Simona 158
Steketee, Richard 100, Plenary
Session IV
Stevenson, Mary 99
Stins, Monique 87
Stok, Edita 124
Stolk, Wilma 76, 152
Stratton, Jennifer 8
Strickman, Daniel 40
Strode, Clare 84
Su, Xinzhou 14
Suaya, Jose 139
Sueker, J. Jeremy 124
Sullivan, David 87
Sun, Wellington 57
Sundar, Shyam 61, 113, 119
T
Takala, Shannon 11
Talisuna, Ambrose 54, 69, 100
Tanner, Marcel 80, 123
Tanowitz, Herbert 16
Tarleton, Rick 31, 37, 74, 104A
Taylor, Terrie Plenary Session I
Taylor, Walter 75
Tekwani, Babu 111
Telford, Sam 15, 36, 46
ter Kuile, Feiko 19
Terrazas, Luis 92
Tesh, Robert Plenary Session II, 153
Thakur, Chandreshwar 113
Thera, Mahamadou 97
Thompson, Andrew 98
Thuma, Philip 54, 122
Tiono, Alfred 101
Torgerson, Paul 9
Torres, Paola 12
Troutt, H. Fred 107
Tsai, Theodore 102
Tsuboi, Takafumi 23
Tucker, Compton 58
Turell, Michael 46
Widdowson, Marc-Alain 112
Wikel, Stephen 79
Williams, Steven 24, 161
Williams, David 123, 141
Wilson, Mary 27
Wilson, Mary 16, 34, 86, 61, 151
Wilson, Mark 46, 157
Wirth, Dyann 14, 103
Wise de Valdez, Megan 84
Woodall, Jack 79
Worrall, Eve 172
Wynn, Thomas 42, 99
X
Xiaonong, Zhou 52
Y
Unnasch, Thomas 24
Urbina, Julio 37
Urdaneta, Ludmel 166
Utzinger, Juerg 52, 88, 123
Yabsley, Michael 157
Yaich, Mansour 160
Yamada, Tadataka Plenary Session I
Yao, Chaoqun 151
Yoksan, Sutee 119
Yoshino, Timothy 165
Yukich, Joshua 65
Yuthavong, Yongyuth 49
V
Z
Vaidya, Akhil 127
Valderramos, Stephanie 137
van der Heyde, Henri 87
Vanderberg, Jerome 22
Vasconcelos, Pedro 153
Vennerstrom, Jonathan 123
Verástegui, Emma 13
Villafana, Tonya 26
Vinetz, Joseph Plenary Session I, 32
Volkman, Sarah 5, 14, 29, 79, 96,
103
Vosshall, Leslie 40
Zaki, Sherif 83
Zavala, Fidel 158
Zikusooka, Charlotte 54
Zimmerman, Peter Plenary Session
I, 79
Zwiebel, Laurence 40
U
W
Waitumbi, John 45
Walker, Edward Plenary Session I
Walker, David 15
Walker, Patricia 138A
Walther, Michael 121
Wang, Anna 19, 93
Wang, Xinhua 106
Ward, Brian 56
Watts, Douglas Plenary Session I,
70
Webster, Joanne 7, 20
Weil, Gary 152
Weina, Peter 95
Wellems, Thomas 106
West, Sheila 38
White, A. Clinton 21, 125
White, Nicholas 71, 93, 116
236
Yes, I wish to join ASTMH as a:
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HOTEL FLOORPLAN
BRIDGE TO LIBERTY &
INDEPENDENCE BALLROOMS
Level 3 — Marriott
Level 3 — Meeting Rooms Across Bridge
BRIDGE FROM HOTEL
238
HOTEL FLOORPLAN
Level 4
Level 5
239

Final Program

Transcription

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