Faculty of Medicine Research Report 2014-2015
Transcription
Faculty of Medicine Research Report 2014-2015
Research Report 2014/15 Research: Funding Trends 82 Patents 25 Departments 790M Total Funding 9118 Total Awards Research in the University of Toronto’s Faculty of Medicine spans ten Toronto sites, collectively known as the Toronto Academic Health Sciences Network (TAHSN). Partners include the Downtown Toronto (St. George) campus of University of Toronto (UofT) and nine affiliated academic hospitals: Baycrest Health Sciences, the Centre for Addiction and Mental Health (CAMH), Holland Bloorview Kids Rehabilitation Hospital, The Hospital for Sick Children (SickKids), Sinai Health System, St. Michael’s Hospital, Sunnybrook Health Sciences Centre, University Health Network (UHN) and Women’s College Hospital (WCH). Total Funding per Site by Year Total Funding per Site 2014/15 3.2M Baycrest 67.8M Sunnybrook 5.4M Holland Bloorview 31.7M CAMH 6.4M WCH 104.6M St. George 248.6M UHN 42.7M St. Mike’s 152.7M Sick Kids 55.9M Sinai Health System Faculty of Medicine Sites in Downtown Toronto 2013-14 2012-13 2011-12 2010-11 $250M 2010-11, 2011-12, 2012-13, 2013-14 $200M $100M Total Funding per Department by Year $150M Site off map $50M Site 2014-15 2014-15 $150M $125M $100M $75M $50M Surgery Speech-Language Pathology Radiation Oncology Psychiatry Physiology Physical Therapy Pharmacology & Toxicology Paediatrics Otolaryngology Occupational Science & Therapy Obstetrics & Gynaecology Nutritional Sciences Molecular Genetics Medicine Medical Imaging Medical Biophysics Immunology IBBME Ophthalmology & Vision Sciences 400 Lab MEdicine & PathoBiology 200 Family & Community Medicine 150 Donnelly Centre 100 Biochemistry 50 Anesthesia $25M Number of Funded Primary Investigators by Department (2014/15) A Message From the Vice Dean Research and Innovation The University of Toronto’s Faculty of Medicine is Canada’s leader in medical discovery research and clinical innovation. This report outlines our impressive research impact and growth for 2014-2015, a year which further strengthened partnerships between the University of Toronto and its nine fully affiliated hospitals. In particular, this year brought new opportunities for major research impacts in cardiovascular health through the Ted Rogers Centre for Heart Research, a collaboration between the University of Toronto, the Hospital for Sick Children, and University Health Network. As we celebrate our research achievements and partnerships, we invite you to join us in the years to come as we continue to break new ground in research and put our ideas into action. - Alison Buchan, PhD, FCAHS Strategic Research Funding Research Themes Research Platforms Funding in Millions Funding in Millions HEALTH 2014/15 INFORMATICS 2013/14 2012/13 2011/12 2010/11 2014/15 HUMAN 2013/14 DEVELOPMENT 2012/13 2011/12 2010/11 FUNCTIONAL 2014/15 IMAGING 2013/14 2012/13 2011/12 2010/11 2014/15 GLOBAL HEALTH 2013/14 2012/13 2011/12 2010/11 CELL & SYSTEMS 2014/15 BIOLOGY 2013/14 2012/13 2011/12 2010/11 2014/15 NEUROSCIENCES 2013/14 & BRAIN HEALTH 2012/13 2011/12 2010/11 OMICS 2014/15 2013/14 2012/13 2011/12 2010/11 KNOWLEDGE 2014/15 EXCHANGE 2013/14 2012/13 2011/12 2010/11 2014/15 COMPLEX 2013/14 DISORDERS 2012/13 2011/12 2010/11 Preparing for Success Development Grant Researcher 0 M $25 M $50 M $75 0M $10 5M 0M $12 $15 0M 5M $17 $20 0M $35 5M 0M $37 $40 0M $35 0M $25 0M $20 0M 0M $15 $10 M $50 Grant Cycle M $25 0 Peer review Grant & program development Service (est. 2011) April 2014 - March 2015 129 proposals edited for 17 agencies 86 researcher clients (41% of St. George Campus researchers) 27% CIHR success rate for operating grants (vs. 15% national success rate) $25,708,000 in research funding All Data from the Faculty of Medicine, Office of the vice Dean, Research and Innovation www.medicine.utoronto.ca/research Design by Alexandra Papaelias & Jamie McMillan International Collaborations: Publications Faculty of Medicine researchers collaborate with peers at leading universities across Canada and around the world. In the map below, the colour scale indicates the number of collaborations between FoM researchers and researchers in our partner countries in 2014. The percentages represent the proportion of FoM internationally co-authored publications by country. 3% 5% 10% 5% 2% 7% 5% 3% 33% Number of Collaborations with FOM Researchers 1000+ 500-999 300-499 200-299 100-199 3% 2% 2% 2% 2% 7% Benchmarking 1.7 1.68 1.70 1.8 1.86 1.9 1.79 UofT Publication Impact 1.75 The Faculty of Medicine’s research output and impact rank the highest among medical research centers in Canada, and compete with best-in-class institutions worldwide. The faculty’s publication output is double that of other major Canadian universities, our research ranks in the top 1 percent by citations among publicly funded universities globally, and measures of our publication impact are consistently well over the global average. 1.6 1.5 2014 Global and Domestic Health Publication Output 1.4 1.3 1.2 1.1 5000 16,529 9659 1000 1000 736 Neuroscience 623 Clinical Neurology 446 Psychiatry 10,726 2000 3000 4000 # of International Collaborations UofT UCL Oxford McGill UBC UCLA 2014 2014 Output of Publications in Strategic Areas 23,258 3000 5571 2013 18,622 2012 0.9 2011 15,790 7000 Global Average 1.0 20,101 2010 # of Web of Science Documents 9000 Michigan UofA # of Citations 5000 766 Oncology 354 Cardiac & Cardiovascular 512 Biochemistry & Molecular Biology 369 Cell Biology Commercialization Patent Applications by Department Patent Applications by Site 10 5 5 Anesthesia Biochemistry Donnelly Centre Family & Community Medicine IBBME Immunology Lab MEdicine & Pathobiology Medical Biophysics Medical Imaging Medicine Molecular Genetics Nutritional Sciences Obstetrics & Gynaecology Occupational Science & therapy Otolaryngology Paediatrics Pharmacology & Toxicology Physiology Psychiatry Radiation Oncology Speech-Language Pathology Surgery UHN 10 Sunnybrook 15 St. Mike’s 15 St. George 20 Sick Kids 20 Sinai Health system 25 CAMH 25 Holland Bloorview 30 Baycrest 30 Includes all patent applications (excluding renewal or updates over the past 6 years) with University of Toronto or an affiliated hospital as an applicant and FOM faculty as inventors as obtained from the PATENTSCOPE database of the World Intellectual Property Organization. For patents with multiple University of Toronto applicants, all sites and departments received credit. 2014/15 Partners in Innovation CANADA Institut de Recherches Cliniques de Montreal McGill Univeristy Université de Montréal University of British Columbia Western University USA COLUMBIA UNIVERSITY JOHNS HOPKINS UNIVERSITY NEW YORK UNIVERSITY NORTHWESTERN UNIVERSITY UNIVERSITY OF CALIFORNIA UNIVERSITY OF CHICAGO UNIVERSITY OF MARYLAND, BALTIMORE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL UNIVERSITY OF TEXAS TUFTS UNIVERSITY Benchmarking Data Ranking information is based on data obtained from the Association of University Technology Managers (AUTM). Totals U of T All U of T All FoM & Hospitals U of T All Canadian Rank North American Rank Top Institutions Invention Disclosures 312 432 1 5 MIT Stanford Univ. Johns Hopkins Univ. 1 2 3 Licenses 107 143 1 7 Univ. of Washington Seattle Univ. of Minnesota Univ. of Pittsburgh 1 2 3 Start-Ups 8 27 1 1 Hospitals + UofT combined 1 Purdue Research Fdn. 2 Stanford Univ. 3 INTERNATIONAL Charite University Hospital King Saud University Vilnius University INDUSTRY Apotex Beckman Coulter Cellaegis Devices Colibri Technologies Forticelle GSK Kraft Roche Tecan Toshiba 2010-2014 Average University systems not included Faculty-Wide Benchmarking 2015/16 2014/15 Times Higher Education (Clinical, Pre-Clinical & Health) 11 13 QS World University Ranking (Medicine) 13 14 National Taiwan University Ranking (Medicine) 3 3 Featured Awardees 2014 Daniel J. Drucker, OC, MD, FRS, FRSC, FRCPC Professor, Department of Medicine Senior Investigator, Lunenfeld-Tanenbaum Research Institute, Sinai Health System Officer of the Order of Canada Fellow of the Royal Society Dr. Daniel Drucker is a world leader in the translational biology of gastrointestinal hormones. His pioneering studies of gut hormone action have enabled development of three new classes of medications for the treatment of diabetes, obesity and short bowel syndrome (SBS), including teduglutide, the first glucagon-like-peptide-2 analogue approved for treatment of SBS. Dr. Drucker is the first Canadian researcher to be honoured with the Manpei Suzuki International Prize, the world’s most valuable prize for diabetes research, and was appointed to the Order of Canada “for his contributions to the development of medicines used around the world to treat diabetes and intestinal disorders.” Angela Colantonio, PhD, FACRM, FCAHS Professor, Department of Occupational Science and Occupational Therapy Director, Rehabilitation Sciences Institute Senior Scientist, UHN - Toronto Rehabilitation Institute Fellow of the Canadian Academy of Health Sciences “Dr. Angela Colantonio leads a broad, internationally recognized program of research on acquired brain injury (ABI) examining ABI in the population, targeting injury prevention and post-acute care with a special focus on how ABI impacts the lives of those most vulnerable to health service inequities, such homeless and older adults and high-risk workers. Dr. Colantonio's research program also examines work-related TBI, long term outcomes among women with ABI, the impact of sex/gender on outcomes, and innovative approaches to intervention, such as the use of theatre as a knowledge mobilization strategy.” – University of Texas Medical Branch Arthur S. Slutsky, MD, MASc, FRSC, FCAHS Professor, Department of Medicine Vice President, Research, St. Michael’s Hospital 2014 CIHR Health Researcher of the Year Fellow of the Royal Society of Canada Dr. Arthur Slutsky was named Canadian Institutes of Health Research (CIHR) Health Researcher of the Year in honour of his outstanding research in critical care medicine and pulmonary care. Dr. Slutsky “has made important discoveries related to the benefits and complications of mechanical ventilation, a life-sustaining therapy in critically ill patients. He has published over 450 peer-reviewed articles and his innovative work has played a major role in improving the way that mechanical ventilation is delivered, resulting in decreased mortality in patients with respiratory failure.” – Royal Society of Canada Anne-Claude Gingras, PhD, FRSC Professor, Department of Molecular Genetics Senior Investigator, Lunenfeld-Tanenbaum Research Institute, Sinai Health System Fellow of the Royal Society of Canada “Dr. Anne-Claude Gingras is an internationally recognized leader in the field of systems biology, having developed and applied innovative new technologies and analysis tools for understanding complex protein-protein interactions associated with human diseases. Her tools and data analysis methods are used by researchers across the globe.” – Royal Society of Canada