İstanbul University Cerrahpaşa Medical Faculty 2015

Transcription

İstanbul University
Cerrahpaşa Medical Faculty
2015-2016 Academic Year
Synopsis of Curricula
For details visit: http://www.ctf.edu.tr/egitim_ogretim/indexen.htm
Istanbul University, Cerrahpaşa Medical Faculty 2015-2016 Academic Year Synopsis of Curricula;
Version 14-Jul-15; Page 1/125
Table of Contents
1st Year Courses .................................................................................................................................. 3
Course 1.1: Introduction to Medical Sciences ..................................................................................... 3
Course 1.2: Cell Tissue and Organ Systems I ...................................................................................... 8
Course 1.3: Cell Tissue and Organ Systems II .................................................................................. 12
Course 1.4: Introduction to Clinical Medicine................................................................................... 19
2nd Year Courses ............................................................................................................................... 25
Course 2.1: Locomotor System .......................................................................................................... 25
Course 2.2: Cardiovascular System ................................................................................................... 28
Course 2.3: Respiratory System ......................................................................................................... 32
Course 2.4: Hematopoietic System, Immunology, Microbiology ..................................................... 35
Course 2.5: Gastrointestinal System .................................................................................................. 39
3rd Year Courses ................................................................................................................................ 43
Course 3.0: Introduction to Internal Medicine Practice ..................................................................... 43
Course 3.1: Nerve System and Sensory Organs ................................................................................ 45
Course 3.2: Genitourinary System ..................................................................................................... 49
Course 3.3: Topographic Anatomy - Biostatistics - Deontology ....................................................... 53
Course 3.4: Endocrine System and Metabolism ................................................................................ 56
Course 3.5: Clinical Microbiology and Infectious Diseases .............................................................. 59
4th Year Clerkships ............................................................................................................................ 62
Internal Medicine ........................................................................................................................... 63
Çocuk Sağlığı ve Hastalıkları / Pediatrics...................................................................................... 67
Gynecology and Obstetrics ............................................................................................................ 71
General Surgery ............................................................................................................................. 74
Radiology ....................................................................................................................................... 77
Anesthesiology and Reanimation................................................................................................... 83
Urology .......................................................................................................................................... 85
5th Year Clerkships ............................................................................................................................ 87
Orthopedics and Traumatology...................................................................................................... 88
Physical Medicine and Rehabilitation............................................................................................ 90
Neurology....................................................................................................................................... 92
Neurosurgery.................................................................................................................................. 94
Psychiatry ....................................................................................................................................... 96
Ophtalmology................................................................................................................................. 98
Otorhinolaryngology .................................................................................................................... 100
Pulmonary Medicine .................................................................................................................... 102
Cardiovascular Surgery ................................................................................................................ 104
Thoracic Surgery .......................................................................................................................... 106
Pediatric Surgery .......................................................................................................................... 108
Radiation Oncology ..................................................................................................................... 109
Plastic and Reconstructive Surgery.............................................................................................. 111
Nuclear Medicine ......................................................................................................................... 113
Cardiology.................................................................................................................................... 114
Infectious Diseases ....................................................................................................................... 118
Forensic Medicine ........................................................................................................................ 120
Dermatology................................................................................................................................. 121
Public Health ................................................................................................................................ 123
6th Year Internships ......................................................................................................................... 125
1st Year Courses
Course 1.1: Introduction to Medical Sciences
Chair:
Assoc. Prof. Dr. M. Selman Demirci, Anatomy
Phone:
E-mail:
+902124143000/21568 Secretary:
selmand@istanbul.edu.tr
+902124143000/21561
Vice Chairs:
Prof. Dr. Remisa Gelişgen, Biochemistry
Assoc. Prof. Dr. Semra Özdemir, Biophysics
Members:
Prof. Dr. Ayten Altıntaş, Deontoloji ve Tıp Tarihi, Deontology and History of Medicine
Assoc. Prof. Dr. Suphi Vehid, Biostatistics
Semester:
1
Credit of Course:
10
ECTS Credit of Course:
10
Departments Included in the Course
Lecture (hour)
Practice (hour)
Proportion (%)
Anatomy
15
4
20
Biophysics
10
4
14
Biostatistics
14
8
21
Biochemistry
18
6
26
Deontology and History of Medicine
13
0
15
Computer in Medicine
0
6
4
Total
70
28
100
Course aims and learning outcomes
Course content
Multidisciplinary course “Introduction to Medical Sciences”
contains,Anatomy,Biophysics,Biostatistics,Biochemistry,Deontology and History of
Medicine,Computer in Medicine lessons.
Course aims
Through anatomy lessons, to the newly started students to medical school, to
introduce 'what is anatomy?' and basic terminology, to teach the basic knowledge
and classification about the places, names, anatomic features of „organs‟ in all
systems to the students of this semester. Thus, to enable them to realize the
importance of anatomy in medical education.
With Biophysics lessons, it‟s aimed that principle function of laser; formation and
properties of ultrasound with the use of these features in medicine and explanation of
the research areas; understanding of the cybernetic concept and specifying the
importance of the clinical use through determining the research areas; determining
the basic biophysical properties of protection from radiation use of radionuclides in
medicine in vitro-in vivo conditions; the importance of optimization of necessary
radiation dose in the treatment planning; education of study areas and biophysical
principles of medical imaging methods as endoscopy, x-ray, computed tomography
(CT), magnetic resonance imaging (MRI), SPECT and PET techniques..
Through the biochemistry lectures; after providing the students gain the basic
knowledge and concepts about the elemental structures, chemical bonds, functional
groups and chemical reactions of biomolecules in human organism, teaching the
classification, structural properties and biomedical importance of nucleic acids,
carbohydrate, lipid, amino acid and protein molecules which are the basic molecules
of cells and tissues, stating the basic knowledge about the relevance of the
molecular structures and functions of hemoglobin and myoglobin, plasma
lipoproteins, serum proteins, immunoglobulins and acute phase reactants, getting to
comprehend the importance of plasma proteins which are clinically important and
their significance in the diagnosis and following up of the diseases, providing this
basic biochemistry knowledge a basis, primarily for the biochemistry lectures which
will be taught in the cell, tissue and organ system lecture course and for the clinical
lectures which will be taught afterwards is intended.
The purpose of Biostatistics course in this committee is : Ensuring appropriate
reasoning about the concepts and issues related to the processes of scientific
research such as variables, , sampling, experimental design, probabilistic
interpretation , capability for their applications and the tendency of adaptation to
solve similar issues.
The purpose of the History of Medicine courses is to provide information about
development of medicine in order to introduce the current medicine to new students.
It is provided information about identity of physician, things made for diagnosis of
disease and treatment method from the primitive man to the Ancient Age and from
there to the Middle Age. It is explained the beginning of the Enlightenment in the
West and how mathematics, physics and chemistry have affected the medicine. It is
tried to be comprehended the system of thought that have given shape to the current
medicine, the beginning of the experimental medicine and how the discovery of the
world of microbiology was made. In this way the History of Medicine courses intend
to be comprehended better education of the current medicine with information about
the science from which the Modern Medicine has arisen and its affection to the
medicine.
Learning
outcomes
A student who completes anatomy lesson in that course; can count out, description
of anatomy, basic terminology, motion system, circulation system, respiratory
system, digestive system, urinery and reproductive system, endocrin system,
nervous system and sensory organs by their Latin names; explain the organs places,
boundaries and basic anatomic features in these systems. He/she can recognise and
show the organs of these systems on cadaver and scaled model. He/she knows the
basic working mechanisms of body systems and their relations with each other.
Students, who attend the biophysics lessons, can know the intended use of laser and
ultrasound in medical treatment and surgery, potential hazards and the selection of
the appropriate laser; can do similar simulations with organism, applying the
cybernetic principles in various medical fields; can evaluate the relative errors of
detected counts on radiation detection; can measure absorption of radiation and can
calculate the half-value thickness in variety tissue sections; can identify the most
accurate method for imaging the internal structures of living organisms and can
explain the biophysical properties of the method.
Students completing this biochemistry lectures in this course should be defining and
arguing the structural properties, functions and biomedical importance of nucleic
acids, carbohydrates, lipids, amino acids and proteins which are the basic
biomolecules of the cells and tissues in human organism, should be defining and
arguing the importance of the relevance of the molecular structures and functions of
hemoglobin and myoglobin, plasma lipoproteins, serum proteins, immunoglobulins
and acute phase reactants and plasma proteins which are important in clinical
diagnosis. Students should be integrating the basic knowledge learned via these
subjects with the knowledge which will be taught in the cell, tissue and organ
systems lectures and should be interpreting and evaluating the resultant changes
related to the biomolecules in physiological and pathological conditions in human
metabolism from a biochemical point of view.
Students who completed the biostatistics course: Can explain the uncertainty , a
feature common in the field of medicine, knows the use of methods to ensure the
analysis and evaluation of such issues. Can examine the types and elements of the
concept of causality , can evaluate basic concepts of biostatistics in the framework of
probability, probability distributions, and probabilistic judgement criteria , acquires
the ability of making scientific analysis based on these informations and to
recognize the structure of the elements in this area.
At the end of the History of Medicine courses; students learn how the medicine was
understood in historical processes commentated in the History of Medicine courses
and definitions about rational drugs in treatment. Thus it will be raised awareness in
students who study the current medicine knowledge. The target of the History of
Medicine courses is to understand, comprehend the current medicine and in
particular to ensure that the future medicine is adapted. At the end of these courses,
the Faculty of Medicine students are provided to comprehend the system of thought
which the medicine has experienced. These courses intend to allow them distinguish
that diagnosis and treatment to be learnt by students during their training of medicine
have arrived at the present days with which development and to allow them be open
for innovations which will rise to the surface in the future.
Teaching
methods and
strategies
Lectures and laboratory practices.
Lectures of the Course
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Title
The Medical Practitioner in History
Philosophical Bases of Medicine
Introduction to Anatomy
Locomotor System (1/3)
Introduction To Biostatistics, Aims, Brief History, Basic Concepts
Biomolecules: General structural properties
Basic Concepts Of Biostatistics, Measuring, Coding, Collection And Presentation Of Data.
Functional groups in biomolecules
The Research Methodology in Medicine, Causality, Research Designs
Vascular System (1/2)
Descriptives Of The Quantitative Data Series
Biochemical reactions
Vascular System (2/2)
Nucleic acids and nucleotides: Structure and functions (1/2)
Nucleic acids and nucleotides: Structure and functions (2/2)
Probability, Basic Concepts, Introduction To Theoretical Probability Distributions
(Binomial, Poisson)
Anatomy of the Human Body as Described and Illustrated in Historical Sources
Introduction To Continuous Probability Distributions (Normal Distribution)
Tests Of Significance I (Parametric Hypothesis Tests)
Respiratory System
Functions of Organs As Viewed in History
Carbohydrates : Structure and classification
Nervous System (1/2)
Nervous System (2/2)
Tests Of Significance II (Parametric Hypothesis Tests)
Tests Of Significance III (Nonparametric Methods)
Monosaccharides, glycosides, oligosaccharides
Polysaccharides and glycoproteins
Etiology of Disease and Methods Used in Diagnosis Before the Scientific Era
Cybernetics and Medical Practices
Proteoglycans, mucopolysaccharides
Gastrointestinal System (1/2)
Evaluation Of Qualitative Data (Chi-Square Test)
Gastrointestinal System (2/2)
Laser and Medical Practices
Lipids: Functions. Fatty acids: Nomenclature and classification
Relation Between Variables I (Correlation)
Relation Between Variables II (Regression)
Urogenital System (1/2)
Ultrasound and Medical Practices
Empirical Methods of Treatment
Struggle Against Infectious Epidemic Diseases in History
Urogenital System (2/2)
Triacylglylcerols, phospholipids, glycolipids
Design Of Experiments, Elements Of Multivariate Analysis
Radiation Biophysics
Isoprenoids, poliprenoids, steroids
Sampling Techniques, Sample Size
Endocrine System
Development of Surgical Instruments and Operations
Sensory Organs
Radiation Biophysics
Plasma lipoproteins
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Title
Biological Effects of Non-Ionisan Radiation and Protection Principles
Introduction of Measurement and Medical Instruments
Amino acids : Structural properties
Medical Experimentation and Evolution of Medicine Evidence
Peptides and proteins : Structural properties
Imaging Techniques
Hemoglobin and myoglobin: Structure and function
Institutionalization in the Field of Medicine
Imaging Techniques: Endoscopy, Rontgen
Historical Bases of Alternative Medicine
Serum proteins, immunoglobulins, acute phase reactants
Computerized Tomography (CT), Magnetic Resonance (MR)
Change of Ethical Values in Medical Practice Through History
Plasma proteins in clinical diagnosis
SPECT, PET
Course 1.2: Cell Tissue and Organ Systems I
Chair: Prof. Dr. Selma Yılmazer, Tıbbi Biyoloji (Medical Biology)
Phone: +902124143000/22032 Secretary:
E-mail: selmayilmazer@mynet.com
+902124143000/21801
Vice Chairs:
Prof. Dr. Ş. Selmin Toplan, Biophysics
Prof. Dr. Gülnur Andican, Biyokimya Biochemistry
Semester
1
Credit of Course:
13
13
Lecture (hour)
Practice (hour)
Proportion (%)
Biophysics
35
12
36
Biochemistry
25
12
28
Medical Biology
36
8
36
Total
96
32
100
Course content
Cell Tissue and Organ Systems I course informs molecular cell biology,
biochemistry and biophysics. Also this course includes acid-base balance
parameters, elements, biomolecules vitamins, enzymes, and basic metabolism
subjects.
Course aims
Teaching the structure and function of cells at molecular level and understanding
the structure and function of biomolecules, vitamins, enzymes and their clinical
importance which will provide basis for course 1003 (Cell, tissue and organ systems
II). Defining the importance of molecular mechanisms of cellular functions in order to
understand the molecular basis of human diseases.
Learning
outcomes
At the end of this course the students will be able to:
Explain properties of Prokaryotic and eukaryotic cells and Evolution of cell
Get information about the examination methods of cell; Cell culture, hybrid cells
Practice of microsurgical procedures to the living cells, fractionation of cells and
analysis of their molecules and Microscopic examination methods of cell
Explain the molecular structure and function of cellular membranes,permeability
specialities , Diffusion Osmosis and Active Transport ,membrane potantiel,
nörobiyofizik,iyon kanalları ve voltaj-klamp tekniği ile Phagocytosis, pinocytosis,
receptor mediated endocytosis
Provide information about the specializations of the cell surface: Microvillus, cilia
and flagella, Cell adhesion molecules and Cell-cell junctions ,Cell to cell
communication and gap junctions, Cell- Extracellular Matrix junctions ,Extracellular
matrix and its proteases
Explain the structural and molecular properties and functions of the cell organelles;
Structure, function and biosynthesis of ribosome, Protein synthesis and genetic
code The mitochondrion, mitochondrial DNA and inheritance, Structure and function
of the endoplasmic reticulum , The Golgi complex and protein sorting, Lysosomes
and lysosomal diseases Peroxisom and peroxsizomal diseases, centriole
Get information about the cell nucleus, nuclear envelope, nuclear pores and
Transport through the nuclear envelope The nucleolus, nuclear matrix Active and
inactive chromatin, The fine structure of chromatin Chromosomes and higher order
structure of chromosomes, centromers, telomers
Explain structure and function of cytoskeleton, microtubulles and intracellular
transport, microfilaments and intermediate filaments
Point out the importance of Cell signalling,signal molecules, Signal transmission
with cell surfaces receptors and intracellular receptors,intracellular signalling
pathways
Explain molecular basis of cell aging, Cell death (apoptosis) and Molecular basis of
cell differentiation
Get information about the Immunobiology and Stem Cell Biology
Dscuss the importance of water metabolism, body water and electrolytes. define
the concept of pH. explain acid-base balance and disorders. point out the
importance of physiological buffers and blood gases. prepare a buffer solution and
calculate the pH of buffer solution and the change in the pH.
Describe the basic information (structures, sources, properties, absorption,
transport, storage, functions, metabolic reactions they participate in, clinical
significance, deficiency states, interactions) on each of the water- and fat- soluble
vitamins as well as macrominerals, electrolytes, essential trace elements required
during the metabolic pathways of macromolecules as well as for a healthy and an
balanced nutrition. explain the methods and principles for the determination of Ca
and P and perform at least one procedure of Ca and P determinations. discuss the
laboratory findings.
Explain general enzyme characteristics, classification, kinetics, mechanism of
action, regulation, its importance in diagnosis and therapy. in laboratory analysis to
be able to draw a grafics, based on experimental conditions related to enzyme
kinetics and to discuss the importance of the findings.
Define the concept of bioenergetics, the laws of thermodynamics and the role of
ATP. explain the anabolic and catabolic pathways, the regulation of overall flux
through a pathway and the location and integration of metabolic pathway.
Discuss the importance of the energy that must use for living cells. explain reactions
involving oxidation and reduction. notice the importance of the respiratory chain
and oxidative phosphorylation and the related diseases
Describe the principles of spectrophotometry and apply this method on
experimental conditions.
Explain the basic mechanisms of vision and hearing
Learn and gain the ability in practicing the electrical currents on tissue both in
diagnosis and therapy
Gain ability in observing the biophysical mechanisms in circulatory system and the
aroused problems
Use the knowledge related to action potential, synaptic transmission and muscle
contraction in laboratory and clinical applications.
Teaching
methods and
strategies
Lectures and laboratory practices
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Title
Body Fluids; Special Features, General Composition, Determination Methodes
Distribution Types of the Matters in Body Fluids
Water, water metabolism and balance of electrolytes
Examination methods of cell; Cell culture, hybrid cells
Biophysical Characterictics of Living structures, Surface Tension
Practice of microsurgical procedures to the living cells, fractionation of cells and analysis
of their molecules
Buffering systems, acid-base balance and its disorders
Vitamins: General properties
Microscopic examination methods of cell
Description and Measurement of pH, Activity of Hydrogen Ions
Regulation of the Acid-Base Equilibrium, Buffering Power of Body Fluids
Prokaryotic and eukaryotic cells
Fat-soluble vitamins
Effects of Systems on Compensation of Asid-Base Equilibrium Disorders
Changes in Acid-Base Parameters in Acid-Base Equilibrium Disorders
Water-soluble vitamins (1/2)
Structure and function of cellular membranes
Biophysical Properties of Blood Gases, Blood Gas Measutrement methods
Blood Gas Electrodes, Blood Sample Drawing and Determination of Acid-Base
Equilibrium Parameters by Nomogram
Organisation of cell membrane and permeability Specialities
Structure and function of cellular membranes
Structure, function and biosynthesis of ribosome
The mitochondrion, mitochondrial DNA and inheritance
Water-soluble vitamins (2/2)
Biophysical Bases of Ionic Diffusion and Osmosis
Biophysical Mechanisms in Active Transport
Membrane Potential, Neurobiophysics and Biophysical Bases of Data Transmission in
Organism
Calcium, phosphate, magnesium
Sodium, potassium, chloride
Formation Mechanisms of Resting Membrane Potential, Ion Channels
Protein synthesis and genetic code
Structure and function of the endoplasmic reticulum
Action Potentials, Ionic Currents,Voltage Clamb Technique
Iron, zinc, copper, manganese, chromium
Molecular mechanisms of protein synthesis in endoplasmic reticulum
Biophysics of Synaptic Conduction
Selenium, cobalt, molybdenum, nickel, lithium and others
The Golgi complex and protein sorting
Potentials in Synaptic Conduction
Bioenergetics
Lysosomes and lysosomal diseases
Biophysics of Muscle Contraction
Enzymes: General properties
Peroxisome, centriole
General concepts of enzymatic action
Mechanism of action of various enzymes
Specializations of the cell surface: Microvillus, cilia and flagella
Enzyme kinetics
Circulaton Biophysics,Hydrostatic Factor in Circulation and Hemodynamic Principles
Mechanisms of ciliary motility
Cell adhesion molecules
Cell-cell junctions and tight junctions
Efficiency and Power of the Heart , Blood Flow and Pressure Measuring Methods
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Title
Enzyme inhibition
Extracellular matrix and its proteases
Cell to cell communication and gap junctions
Hemarheology; Aims, Fluidity Specialities of blood Flow
Blood Viscosity, Erythrocyte Deformability and Other Rheological Specialities
Nucleus, nuclear envelope, nuclear pores
Regulation of enzyme activity (1/2)
The nucleolus, nuclear matrix
Transport through the nuclear envelope
Regulation of enzyme activity (2/2)
Atomic Specialities That Determine the Structural Physical Characterictics of
Biomolecules, Reasons of Moleculer Changes and liveness
Interactions Between Molecules and Orientation, Intermolecular Recognation and
Relation of Recognation With Structural Specialities
Membranes: Chemical structure and organisation
Active and inactive chromatin, The fine structure of chromatin
Chromosomes and higher order structure of chromosomes, centromers, telomers
Molecular movements at membrane; passive transport systems
Biomoleculer Activation and Inactivation, Principles and Laws of Biomoleculer Life
Success; Intercellular and Intracellular Regulation of Molecular Processes
Phagocytosis, pinocytosis, receptor mediated endocytosis
Enviromental Specialities that Biomolecules Take Place In
Cytoskeleton I: Microtubulles and intracellular transport
Active transport systems
Receptors and signal transduction
Cytoskeleton II: Microfilaments and intermediate filaments
Cell signalling
Introduction to metabolism, Biologic oxidation
Regulation of molecular functioning inside and outside the cell
Classification of Principles of Spectrophotometry, Light Energy, Organism Relation
Molecular Mechanisms of Convertion of the Light Energy in Organism, Electrogenic
Action Potential
Electron transport chain
Signal transmission with cell surfaces receptors and intracellular receptors
Molecular basis of cell aging
Oxidative phosphorylation
Mechanical Energy Organism Relation, Organisation of Coclear Potential and Ionic Bases
Cell death (apoptosis)
Physical and Chemical Effects of Direct Current, Effects of Direct Current on Tissue
Evolution of cell
Current specialties According to Frequency and Intensity
Molecular basis of cell differentiation
Immunobiology
Control Mechanisms in Replication and External Intervention
Stem Cell Biology
Immunobiophysics General Concepts, Reorganisation of DNA
Choronaxie, Rhobase, Stimulation of human by Direct Currents, Surgical Galvanism
Course 1.3: Cell Tissue and Organ Systems II
Chair: Prof. Dr. Turgut Ulutin, Tıbbi Biyoloji (Medical Biology)
Phone: +902124143000/22208
E-mail: ulutin@istanbul.edu.tr
Secretary:
+902124143000/21801
Vice Chairs:
Prof. Dr. Gökhan Metin, Physiology
Assoc. Prof. Dr. Emine Elif Güzel, Histology and Embryology
Members:
Prof. Dr. Bora Barutçu, Biophysics
Prof. Dr. Orkide Donma, Biochemistry
Semester:
2
Credit of Course:
13
13
Lecture (hour)
Practice (hour)
Proportion (%)
Biophysics
9
10
11
Biochemistry
10
0
8
Physiology
19
4
18
Genetics
28
8
27
Histology and Embryology
37
12
36
Total
103
34
100
Course content
Multidisciplinary course “Cell Tissue and Organ Systems II” contains, anatomy,
biophysics, biostatistics, biochemistry, history in medicine and computer in
medicine lessons.
Course aims
Biophysics: Functional Structure of the Proteins and It‟s Biophysical Specific
Features, Thermodynamic Principles and Regulation of Energy Transfer in Living
Structures, Biophysical specialties of Usage of Metabolic Energy in Biological
Work, Irregular Cell Proliferation Mechanisms, Nanotechnology and its medical
applications, Biomechanics, Biological Effects of Ionian Radiation, Effects of
Radiation in Cell, Biophysics of Cell Proliferation and Differentiation, Tracers, Radio
sensitivity, Radiopharmaceuticals and Their Biological Behavior.
The course board should provide groundwork about, the main structure of a cell,
the functions and structures of cells & tissues, cell cycles, the types of transmission
between cells, the normal structures & functions of a body system.
Even it seems like every vital is moving independently, the effects from inner &
outer dynamics are bonded to the mechanic rules. Because of this, it should have
information about the important research & development area of biomechanics.
The nanotechnology could create intervention of the living systems in the molecular
levels, in this aim the nanotechnology should be considered as the new and
providing diagnosis & cure method.
It should explain the biological affects & protection methods about radiation.
It should understand the radiopharmaceuticals Biological Behavior Mechanisms.
Biochemistry: Digestion of dietary nucleoproteins. Metabolisms of purine and
pyrimidine nucleotides. Diseases related to the synthesis as well as degradation
pathways. DNA mutations and repair mechanisms. Stages of replication and
transcription. Posttranscriptional events. General principles and stages of
translation. Posttranslational modifications. General mechanisms on the regulation
of gene expression and protein targeting. Growth, differentiation, the loss of
control on growth and tumor development. Biochemical alterations observed in
tumor cells. Laboratory tests for the detection of such alterations.
To discuss the importance of metabolism of nucleotides, stages of replication and
transcription in prokaryotes and eukaryotes, their regulations, associated enzymes
and accessory proteins as well as types of mutations caused by several agents for
the understanding of metabolic alterations at molecular level, particularly in genetic
diseases. To emphasize the clinical significance of repair mechanisms and the
related defects. To acquire proficiency about the importance of the inhibition of
transcription in treatment protocols. To explain posttranscriptional events and their
regulations. To explain the mechanism of action of HIV inhibitors. To explain the
stages of translation and the effects of inhibitors during the course of treatment. To
explain regulation of gene expression within the scope of metabolic events in the
body. To explain the processes those take place within the scope of protein
targeting. To introduce what type of a disease cancer is, how it develops, the roles
of oncogenes during the course of cancer development. To emphasize the role of
the laboratory during the monitoring of cancer patients as well as the clinical
significance of tumor markers on diagnosis.
Physiology: This course is a continuation of the Cell Tissue and Organ Systems I
and provides basis for Clinical Medical Sciences. This course aims to
apprehension of the structure and function of cells and tissues and their clinical
importance in physiological level.
Basic genetics: Organization of human genom and gene structure,DNA structure
and replication, mutations, DNA repair ,gene expression;transcription and protein
synthesis ,regulation of gene expression, recombinant DNA technology Genetic
engineering and human genom project . cell division and cell cycle control system
,Cell cycle regulation and cancer development, cancer causing genes, Meiotic
division and formation of gamets, chromosome structure,Isolation of chromosomes
,Chromosomal abnormalities, Mendelian inheritance , autosomal inheritance
Multifactorial inheritance, mitochondrial inheritance, Recessive inheritance, X
linked inheritance, concept of Genomic imprinting, uniparental
disomy,immunogenetics.
To discuss the importance of genetics and explain the basic principles of
molecular genetics, organization of human genom and gene structure,DNA
structure and replication ,the clinical significance of mutations, To explain
molecular steps of gene expression;transcription and protein synthesis ,regulation
of gene expression , To acquire proficiency about the principles of recombinant
DNA technology Genetic engineering and human genom project . To emphasize
the significance of the cell division and cell cycle control system for the
understanding of cancer development and cancer causing genes.To explain
structure of chromosomes,Isolation of chromosomes and Chromosomal
abnormalities, Mendelian inheritance (definitions), autosomal inheritance
Multifactorial inheritance, mitochondrial inheritance, Recessive inheritance, X
linked inheritance, concept of Genomic imprinting, uniparental disomy, To explain
The general properties of genetic disorders
Histology: General histology
Histology & its methods of study
The microscopical structure of the cell and the four fundamental tissues of the body
(epithelial, connective, nerve, and muscle tissue).
General embryology
Embryonic molecular regulation and signaling.
Gametogenesis: Conversion of germ cells into male and female gametes.
First week of development: Ovulation to implantation.
Second week of development: Bilaminar germ disc.
Third week of development: Trilaminar germ disc.
Third to eighth weeks: The embryonic period.
The gut tube and the body cavities.
Third month to birth: The fetus and placenta.
General aspects of birth defects and prenatal diagnosis.
General Histology
To teach and discuss the importance of the General Histology, it‟s methods of
study, and the microscopical structure of the epithelial, connective, nerve, and
muscle tissues.
General Embryology
To teach and discuss; the importance of the embryonic molecular regulation and
signaling, what is gametogenesis and how germ cells convergence to male and
female gametes, the important events in the 1st week of development from
ovulation to implantation, the events in 2nd week of development and formation of
bilaminar germ disc, 3rd week of development and formation of trilaminar germ
disc, the embryonic period of 3rd to 8th weeks of development, formation of the gut
tube and the body cavities, development and growth of the fetus during 3rd month
to birth and formation of placenta, and finally emphasize the general aspects of the
birth defects and their prenatal diagnosis.
Learning
outcomes
Biophysics: The cell in the living organism, should recognize the organs & the
systems, should define them with the proper terminology, compare & explain
between the related tool, methods & principles.
The main structures of cells & tissues should comprehend the fundamentals,
functions and relations.
It should understand & regard the principle of biochemical & physical chemistry
affects between the inner cell & between the cells.
To ensure & protection of the homeostasis in the organism, the structure &
functions of the systems should be defined & thought as a whole.
Biochemistry:
The student will be able to
-introduce digestion of nucleic acids,
-find out the synthesis pathways of purine nucleotides, key regulatory points and
their significance
-explain the clinical consequences of deficiencies or
overactivities of the related enzymes.
-provide information about uric acid and the related diseases.
-explain the defects related to synthesis and degradation pathways of pyrimidine
nucleotides.
-explain the general features of replication in prokaryotes and eukaryotes as well
as how DNA synthesis is performed with great fidelity.
-find out the compounds and the intermediates participating in replication process
as well as the enzymes in the replication fork and their functions.
-explain the control mechanisms during replication
-explain the inhibition of replication and DNA mutations
-get information about repair mechanisms and their significance
-list the types of RNA
-list the key molecules, stages and control mechanisms of transcription
-notice the importance of transcription during physiological and pathological events
-explain defects in transcription
-point out the importance of the inhibition of transcription during treatment protocols
-explain posttranscriptional events, parameters, which are involved in the process
and the period prior to translation
-List the basic principles and steps of translation, posttranslational modifications
and the inhibitors of translation along with their mechanisms of action
-Give some information about the general biochemical mechanisms, which play
roles in regulation of gene expression as well as protein targeting and also
diseases caused by the defects in these regulatory mechanisms
-provide information about genes regulating cell cycle, DNA repair genes,
prooncogenes, oncogenes, tumor suppressor genes, genes regulating apoptosis
and the events during the course of cancer development
-define the concept of tumor marker. Know the roles of tumor markers in cancer
screening, diagnosis, differential diagnosis, staging, prognosis determination,
planning and monitoring of treatment, detection of recurrence. Know the properties
of an ideal tumor marker. List tumor markers used in the clinical disciplines. Know
that they are detectable in serum and also other physiological fluids such as urine,
CSF, BAL as well as in the cancerous tissues of the patients, but also in some
benign conditions.
Know the necessity of preferring noninvasive and low-cost techniques
Physiology:
Understanding the concept of homeostasis in the organism. Understanding the
properties of body fluid compartments and their interrelations. Understanding the
exchange of fluids between the intracellular and extracellular fluid compartments,
and how the osmotic equilibrium is established. Learning the physical properties of
blood and the conditions that change these properties. Understanding the
physiologic structure of the cell membrane. Learning the mechanisms which allow
the passage of substances through the cell membrane and the tissue specific
transport mechanisms. Understanding how resting membrane potential occurs and
the role of ion channels in this process. Describing the ionic basis and conditions of
excitation and types of action potential. Understanding the mechanism of excitation
in excitable tissues.Understanding the physiological properties of nerve cells which
have an excitable and conducting nature. Describing the classification of the nerve
fibers and their fiber specific functions. Understanding the types of communication
in the intercellular communication processes and the intra-and extracellular
mechanisms that take part in intercellular communication. Understanding the
cellular and electrical properties of smooth and cardiac muscle. Describing the
ionic basis of contraction and relaxation processes. Understanding the differences
of these muscles from skeletal muscle. Understanding the general theories about
aging physiology. Understanding the mechanisms of aging and death and their
relationship between apoptosis and oxidant systems.
Basic genetics:
The student will be able to:
Explain the organization of human genome ,DNA structure,Gene structure, gene
families, repetitive DNA sequences,
Find out DNA replication ,DNA damage and repair; The nature of mutations .
Provide information about principles of recombinant DNA technology Genetic
engineering and human genom project
Transcription and regulation of gene expression
Explain cell cycle, mitosis and Molecular genetics of the cell cycle control
systems .Cell cycle regulation and cancer cells, proto-oncogenes, oncogenes
tumor suppressor genes and the genetics of cancer
Point out the importance of Meiosis and formation of germ cells, genetic
recombination
Get information about the Molecular and biochemical basis of genetic disorders
Treatment of genetic diseases and gene therapy
Explain Isolation of chromosomes and Chromosomal abnormalities ,
Provide information about Mendelian inheritance (definitions), autosomal
inheritance Multifactorial inheritance, mitochondrial inheritance, Recessive
inheritance, X linked inheritance ,The general properties of genetic disorders
Define the concept of Genomic imprinting, uniparental disomy,
Give some information about Immunogenetics
Histology:
The student will be able to understand what histology and its methods are. They
will learn and recognize the microscopical structure of the four basic tissues of the
human body. On the next step they will be prepared to identify these tissues in
organs and systems of the body. This will help the student to realize how they
blend with each other to form the organs, organ systems and the body.
As far as embryology is concerned the student will understand the steps in
molecular regulation and signaling of the embryonic cells and how they influenced
themselves in body formation. They will learn how gametes are formed. They will
learn the differentiation and development of the structures during embryonic period.
They will understand the formation of gut and the body cavities. They will have an
idea about the development and growth of the fetus and the placenta. All through
these steps the student will have a chance to learn the congenital abnormalities
and their relationships that may occur and understand how prenatal diagnosis is
important.
Teaching
methods and
strategies
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
30.
31.
32.
33.
34.
35.
36.
37.
38.
39.
40.
41.
42.
43.
44.
45.
46.
47.
48.
49.
50.
51.
52.
53.
54.
Title
Digestion of nucleic acids. Metabolism of purine nucleotides
Introduction, Gene structure
Histology & Its Methods of Study
Metabolism of pyrimidine nucleotides
Epithelial Tissue I
Introduction to Physiology
Organization of genomes
Epithelial Tissue II
Homeostasis
Body fluids and body fluid compartmens
Epithelial Tissue III
Gene families, pseudogenes, repetitive DNA sequences
DNA replication
DNA synthesis
Connective Tissue I
DNA damage and repair; The nature of mutations
Fluid exchange between intra- and extracellular compartmens
Connective Tissue II
Connective Tissue III
DNA repair and mutations
Physical properties of the blood
Physiological properties of the cell membrane
RNA synthesis
Connective Tissue IV
Cartilage
Posttranscriptional modifications of RNA, RNA-dependent synthesis of nucleic acids.HIV
inhibitors
Principles of recombinant DNA technology
Bone I
Biosynthesis of proteins
Transport of ions and molecules across the cell membrane
Membrane potentials, Genesis of resting membrane potentials
Bone II
Genetic engineering and human genom project
Transcription, control of the gene expression
Excitation of the excitable tissues
Bone III
Regulation of gene expressıon and protein targeting
Blood Cells I
Blood Cells II
Cell cycle, mitosis
The cell cycle control system
Blood Cells III
Hematopoiesis
Molecular genetics of the cell cycle control systems
Ionic basis of excitation, types of action potentials
Cell cycle regulation and cancer cells, proto-oncogenes, oncogenes and tumor
suppressor genes
Oncogenes, Tumor Supressor Genes and cancer
Tumor markers
Nervous Tissue I
Nervous Tissue II
Physiological properties of nerve cells,Classification and function of nerve fibers
Intracellular Communication-I
Intracellular Communication-II
The genetics of cancer
No
55.
56.
57.
58.
59.
60.
61.
62.
63.
64.
65.
66.
67.
68.
69.
70.
71.
72.
73.
74.
75.
76.
77.
78.
79.
80.
81.
82.
83.
84.
85.
86.
87.
88.
89.
90.
91.
92.
93.
94.
95.
96.
97.
98.
99.
100.
101.
102.
103.
Title
Functional Structure of the Proteins and It‟s Biophysical Spesific Features
Meiosis and genetic recombination
Nervous Tissue III
Nervous Tissue IV
Muscle Tissue I
Smooth muscle and electrical properties
Molecular and biochemical basis of genetic disorders
General theories about aging, cellular death and apoptosis
Mechanisms of aging, cellular death and apoptosis
Ionic mechanisms of the Smooth muscle contraction and relaxation
Muscle Tissue II
Molecular basis of genetic disorders
Treatment of genetic diseases and gene therapy
Electrical Properties of the cardiac muscle, cellular and ionic mechanisms of the heart
muscle contraction and relaxation
Comparition of the cellular, electrical and mechanical properties of the smooth and
cardiac muscles with skeletal muscle
Muscle Tissue III
Mendelian inheritance (definitions), autosomal inheritance
Recessive inheritance, X linked inheritance
Multifactorial inheritance, mitochondrial inheritance
Muscle Tissue IV
Introduction to Embryology-Molecular Regulation & Signalling
Genomic imprinting, uniparental disomy
Gametogenesis I
Gametogenesis II
Isolation of chromosomes
1st Week of Development Ovulation to implantation
2nd Week of Development (Bilaminar Germ Disc)
Thermodynamic Principles and Regulation of Energy Transfer in Living Structures,
Biophysical specialities of Usage of Methabolic Energy in Biological Work
The methods of isolating chromosomes
3rd Week of Development (Trilaminar Germ Disc)
3rd To 8th Weeks of Development (Embriyonic Period) I
3rd To 8th Weeks of Development (Embriyonic Period) II
Irregular Cell Proliferation Mechanisms
Chromosomal abnormalities I
Chromosomal abnormalities II
Nanomedicine concept: from laboratory to current practice
Fetal Period
Immunogenetics
Biological Effects of Ionian Radiation
Biomechanics
Fetal Membranes and Placenta
Twins and birth
Tracers, radiosensitivity, radiopharmaceuticals and their biological behavior
Biophysical approaches in cell cycle and differentiation
Tracers, Radiosensitivity, Radiopharmaceuticals and Their Biological Behavior
Birth Defects and Prenatal Diagnosis
Body cavities and serous membranes
Course 1.4: Introduction to Clinical Medicine
Chair: Prof. Dr. Hacı Murat Emül, Psychiatry
Phone: +902124143000/23013 Secretary:
E-mail: hmuratemul@hotmail.com
+902124143000/21768
Vice Chairs:
Prof. Dr. Oktay Demirkıran, Anesthesiology and Reanimation
Prof. Dr. Suat Hilal Akı, Pathology
Members:
Prof. Dr. Ahmet Gökhan Akkan, Pharmacology
Prof. Dr. Hrısi Bahar, Microbiology
Semester:
2
Credit of Course:
10
10
Lecture (hour)
Practice (hour)
Proportion (%)
Anesthesiology and Reanimation
6
8
10
Child and Adolescent Psychiatry
3
0
3
Pharmacology
20
0
21
Microbiology and Clinical Microbiology
10
2
12
Nuclear Medicine
2
0
2
Pathology
28
8
33
Psychiatry
19
0
19
Total
88
18
100
Course content
Course aims
Multidisciplinary course “Introduction to Clinical Medicine” contains, Anesthesiology
and Reanima,Pharmacology,Microbiology and Clinical Microbiology,Nuclear
Medicine,Pathology,Psychiatry lessons.
Pharmacology
1. Introduction to Pharmacology
Teaching the branches and divisions of pharmacology and their role in medical
sciences, related terminology and their historical prospective.
2. Pharmacokinetics
Learning pharmacokinetic properties of drugs
3. Pharmacodinamics
Learning the mechanism of action of drugs and their underlying basic principles,
treatment design based on these principles
In this course, it was aimed the students, to learn the theories related wıth
microbiology in a level which will constitue a base for their learnings in advanced
classes, to have notion about bacteria, fungi, parasites ,vıruses and prions, to gain
proficiency in a level which will serve them for microscobic examination of bacteria
cine,
Pathology:
Description of factors and morphological features of cell degeneration and cell
death, description of features of inflammatory reactions, explanation of tumorneoplasia concept and their mechanisms, description and explanation of
morphological features of hemodynamic disorders and their consequences.
Learning
outcomes
Psychiatry
The students throughout this course:
They should scrutinize the possible contributions of central nerve system and
related biological systems to forming of human behavior
Alongside biological developing, they should think about the influences of
psychosocial development on the existence of human beings.
They should recognize the psychological sub structures and causals of the
behavior and attitudes in normal human beings.
They should analyze the role of biological and psychic structures in the
development of mental illnesses.
Alongside psychiatric illnesses, they should handle medical diseases and all
patients within all biopsychosocial dimensions.
Pharmacology
a. Knowledge
Terminologies of pharmacology, drug and medicine
The perspective of historical development of pharmacology in the world and in our
country
Pharmacology and its sub branches
Pharmacodynamics,
Pharmacokinetics,
Pharmacognosy,
Pharmacogenetics, Pharmacy, Pharmacotherapy, Clinical pharmacology and
Toxicology
Source of drugs, natural and synthetic drugs, herbal medicines, chemistry of active
drug(substance), pharmaceutical formulation, drug dose and dosage form
Pre clinical drug development and stages of drug development (Phase I, II, III, IV),
Legislative provisions for drug, and to get knowledge regarding pharmacopoeia.
b. Skills
The course is theoretical, knowledge will be applied in clinical practice.
c. Attitute
Pharmacology and related concepts are applicable in other fields of medical
sciences.
2. Pharmacokinetics:
a. Knowledge
Introduction to the pharmacokinetic process, stages (absorption, distribution of drug
in the organs, process of absorption)
Factors affecting the drug absorption ( Cell membrane, tissue cells, biochemical
and vascular properties), simple diffusion, active diffusion, facilitated diffusion, to
articulate mathematical parameters of digestion and absorption
Molecular size and polarity of the active ingredient, effect of dosage form, pre
systemic elimination
Bioavailability
Dosage form and routes of administration of drugs (systemic enteral and parenteral
routes, local drug administration), dosage form according to the route of
administration
Drug distribution, volume of distribution and its mathematical description, factors
affecting the tissues and distribution of drug molecules, plasma protein binding,
sequestration and redistribution
Biotransformation of Drugs, phase I and phase II biochemical reactions, factors
affecting the biotransformation and pharmacogentics.
Disposal of drugs and metabolites from the body (excretion), route of excretion like
renal excretion, liver and biliary excretion, hepatic and renal clearance, elimination
half-life and mathematical calculations, Alternative Therapies in Health and
Medicine-(ATHM) (types of dialysis)
Study of pharmacokinetic models, Single compartment, two compartment and
multiple compartment model, dose-concentration relationship, plasma
concentration-time curve after I.V and PO single dose administration, its
mathematical calculations, plasma concentration-time curve after repeated drug
administration (I.V, PO), concept of steady-state plasma concentration and its
mathematical calculations, degree of drug accumulation, loading dose and
mathematical expressions will be discussed.
b. Skills
Calculation of dosage form according to the pharmacokinetic parameters, time to
reach steady-state plasma concentration and therapeutic drug monitoring.
c. Attitute
Rational use of drugs based on pharmacokinetic parameters.
3. Pharmacodynamics
a. Knowledge
The principle mechanism involved in drug action (role of receptors and other
mechanism)
Role of cellular mechanism (endogenous ligand receptors) in drug action, ion
channels, genetic determination of these basic elements along with enzymes and
carrier molecules, receptor subunits, agonist and antagonist of these substances,
physico-chemical structure of the drug and molecule-receptor specificity, role of
chemical bonds
Postreceptor signal transduction mechanisms: G protein and adenylate cyclase /
cAMP system, phospholipase C / inositol phosphate system and calcium ion,
guanylate cyclase / cGMP system, phospholipase A2. Examples of drugs that affect
these systems.
Other mechanism affecting the drugs mode of action
Drug effect–(response) measurements, types of pharmacological dose-response
(graded, Quantal or all or none response, fixed and variable factors affecting dose
response), dose-response curves and related mathematical considerations,
theoretical approach to drug receptor interaction and its mathematical expressions,
factors modifying drug action (body weight and volume, age, gender, organ
diseases and physiological conditions that affect the dynamics and kinetics of a
drug, time and route of administration of the drug, social and geographical
environment and dietary patterns of the person, genetic factors, biological
variability, change in drug response after continuous use, tolerance, tachyphylaxis,
desensitization, combination of drugs and the placebo effect) and compliance.
Pharmacokinetic and pharmacodynamic interactions of combined drug therapy,
types of pharmacodynamics interactions (types of antagonism and agonistic
interactions). Demonstration of dose-response curves and mathematical expression
of these interactions with specific examples. Types of pharmacokinetic interaction
(absorption, distribution and protein binding, metabolism and excretion with related
interactions) along with specific examples.
Effect of the drug according to the time period, response-time graph
b. Skills
Drug therapy can be selected according to patient‟s pathology with knowledge
about mechanism of drug action and change in it.
c. Attitute
Rational use drug therapy based on the pharmacodynamic principles
Microbiology and Clinical Microbiology At the end of this course, the students can
explain the basic theories related with microbiology. They can discuss the general
characteristics of bacteria, fungi, parasites, virus and prions.They can examine
bacteria in microscope preparing a slide and they can realise the importance of
microorganisms and microscope .
Pathology
Knowledge
Define and explain of the types of cell injury.
Identify and categorize the adaptive changes.
Explain of cell aging.
Explain the etiology and mechanisms of inflammation.
Categorize the pathogenesis and episods of inflammation.
Describe the types and morphology of inflammation.
Explain and categorize the types, circumstances and affecting factors of wound
healing.
Describe neoplasia and designate neoplasia according to the tissue type orginating
from.
State differential diagnostic features of benign and malignant tumors.
Explain mechanisms of carcinogenesis.
Explain tumor immunity.
Explain mechanisms and clinical reflections of edema and hydration states.
Explain reasons, morphological features and clinical reflections of hyperemia and
hemorrhage.
Categorize and explain mechanisms, types, consequences and complications of
thrombus and embolism.
Explain mechanisms, morphological types and styles of repair of ischemia and
infarction.
Define and explain reasons, types, mechanisms, morphological features and
clinical reflections of shock.
Categorize and explain reasons, types, mechanisms, clical and morphological
fetures of hypertension.
Teaching
methods and
strategies
Ability
Define cellular mechanisms of pathological basis of diseases and categorize
morphlogical and clinical findings of inflammatory lesions and hemodynamic
disorders.
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
30.
31.
32.
33.
34.
35.
36.
37.
38.
39.
40.
41.
42.
43.
44.
45.
46.
47.
48.
49.
50.
51.
52.
53.
54.
55.
Title
Introduction to pharmacology (1/2)
Introduction to Pathology, Definitions
Introduction to C.N.S: psychology and behavior theories. neurons and synapses
Introduction to Medical Microbiology,
Cell injury and the mechanisms
Introduction to C.N.S: cognitive functions
Cell injury and the mechanisms II
Introduction to pharmacology (2/2)
Cellular response to injury: Degeneration, necrosis, apoptosis
Perception
What is first aid?
Routes of Practice of Drugs (1/2)
Routes of Practice of Drugs (2/2)
Cellular adaptation: Hyperplasia, hypertrophia
Attention and voliton
Microbial Taxononomy Eucaryotes and Procaryotes and classification of bacteria
Cellular adaptation: Atrophia and metaplasia
Motivation and Drive
Pharmacokinetics (1/4)
Intracellular accumulations and pathologic calcifications
Defense mechanisms and theories
Evaluation of patient and vital signs
Body fluids, edema, dehidratation
Genetics in psychiatry
Psychoneuroendocrinology
Bacterial morphology, physiology and metabolism
Hyperemia, congestion, hemorrhage
Hemostasis and thrombosis
Memory
Mechanisms of Drug Actions (1/2)
Intelligence and related psychopathology
Introduction to Bacterial genetics
Basic life support I (Automated external defibrilator)
Thromboembolism
Ischemia and infarct
Shock, Hypertension
The concept of inflammation, inflammatory cells and elements
Personality Disorder
Mechanisms of Drug Actions (2/2)
Normal Microbial flora
Chemical mediators of of inflammation
Stres reaction and coping mechanisms
Drug Receptors, Signal Transduction and Drug-Receptor İnteraction (1/2)
Pathogenesis of acute inflammation
Basic life support II - Airway Obstruction, Recovery Position
General Properties of Viruses and prions
Leukocyte extravasation, adhesion and transmigration; chemotaxis and phagocytosis
Addiction
Drug Receptors, Signal Transduction and Drug-Receptor İnteraction (2/2)
Chronic inflammation, angiogenesis, fibrosis
Emotions and feelings
Dose (Concentration)-Effect Relationship (1/2)
No
56.
57.
58.
59.
60.
61.
62.
63.
64.
65.
66.
67.
68.
69.
70.
71.
72.
73.
74.
75.
76.
77.
78.
79.
80.
81.
82.
83.
84.
85.
86.
87.
88.
Title
Healing of the inflammation: Regeneration and reperation
Neurotransmitters in Psychiatry
Behavioral and Emotional Problems in Children
Introduction to neoplasia, definition nomenclature of tumor
Paediatric Basic Life Support
General Properties of Fungi
Properties of benign and malign neoplasias, epithelial and nonepithelial tumors (1/3)
Dose (Concentration)-Effect Relationship (2/2)
Adolescent Psycology
Factors That Modify Drug Actions and Drug İnteractions (1/2)
Pschosocial and physical development theories
Factors That Modify Drug Actions and Drug İnteractions (2/2)
Simple and conditioned reflexes and behaviour
Chemical and viral carcinogenesis
Bleeding management and Shock
Roles of oncogenes, tumour supressor genes, and genes that regulate DNA repair at
cancer generation; steps of cancer generation (1/2)
General properties of protozoa and helmints
Basic Physics in Nuclear Medicine and Instrumentation
Perception
Roles of oncogenes, tumour supressor genes, and genes that regulate DNA repair at
cancer generation; steps of cancer generation (2/2)
Radiopharmacy and Tracer Kinetics
Adverse drug reactions (drug toxicology) (1/2)
Psycholgy in late life
Tumor kinetics and progression; pathogenesis of invasion and metastasis; angiogenesis
(1/2)
General Properties of Arthropods
Tumor kinetics and progression; pathogenesis of invasion and metastasis; angiogenesis
(2/2)
Developmental Pathologies in Children
Adverse drug reactions (drug toxicology) (2/2)
Environment and microorganisms
Pharmacogenetics (1/2)
Pharmacogenetics (2/2)
2nd Year Courses
Course 2.1: Locomotor System
Chair:
Prof. Dr. Güler Kahraman Yıldırım, Anatomy
Phone: +902124143000/22496
E-mail: gulerk@istanbul.edu.tr
Secretary:
+902124143000/21563
Vice Chairs:
Prof. Dr. Kenan Akgün, Physical Medicine and Rehabilitation
Prof. Dr. Nuran Darıyerli Toktamış, Physiology
Members:
Prof. Dr. Tania Marur, Anatomy
Assoc. Prof. Dr. Mehmet Can Ünlü, Orthopedics
Semester:
3
Credit of Course:
8
8
Lecture (hour)
Practice (hour)
Proportion (%)
Anatomy
21
14
42
Biochemistry
3
0
4
Pediatrics
3
0
4
Infectious Diseases
2
0
3
Pharmacology
5
0
7
Physical Medicine and Rehabilitation
3
0
5
Physiology
5
2
9
3
0
5
Internal Medicine
3
0
5
Nuclear Medicine
1
0
1
Orthopedics and Traumatology
3
0
5
Pathology
5
2
9
Radiodiagnostics
1
0
1
Total
58
18
100
Course content
Locomotor system course gives information about the normal structure,
development and functions of bones, joints and muscles,
system related diseases, (etiology,symptoms,
basic clinical and laboratory findings,
diagnostic methods) and drugs used for system related diseases.
Course aims
Learning
outcomes
Teaching
methods and
strategies
At the end of the
course; the students should learn function, structure, development, and
physiopathology
of Locomotor System ( bones, joints, muscles) and basic clinical
and laboratory diagnostic methods, drugs used for system related diseases.
By the end of the Locomotor System course the student should be able to:
1. Describe anatomical structures,
2. Describe development and embryonic origins,
3. Describe histological structures,
4. Describe functional mechanisms,
5. Describe Etiopathogenesis, clinical findings,
6. Describe radiological images,
7. Describe terapoetic methods,
8. Describe mechanism of action and effects of system related drugs of the
Locomotor System.
Lectures, laboratory practices, homework, interactive presentation, demonstration,
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
30.
31.
32.
33.
34.
35.
36.
Title
Locomotor System, Introduction
Bones of Upper Limb
Biochemistry of bone
Bones of Lower Limb
Bones of Axial Skeleton, Vertebra, Ribs, Sternum
Biochemistry of connective tissue
Histology of Bone, Cartilage and Muscle
Development of the Skeletal System
Cranium, Neurocranium
Fracture and healing of fracture, bone infection
Physiology of Bone
Viscerocranium
Head as a whole I
Bone diseases due to metabolic dysfunction
Head as a whole II
Bone scintigraphy and bone densitometry
Osteomyelitis
Bone lesions of unknown origin / tumour like lesions , Bone tumors 1
Joints, Introduction
Joints of Upper limbs
Bone lesions of unknown origin / tumour like lesions , Bone tumors 2
Joints of Lower Limb I
Joints of Lower Limb II
Septic arthritis
Joint diseases and soft tissue tumors
Joints of Axial Skeleton
Peripheral Nervous System (1/2)
Peripheral Nervous System (2/2)
Muscles, Introduction
Muscles of Head and Neck
Biochemistry of muscle
Development of the Muscle Tissue
Neuromuscular transmission
Muscles of Upper Limb
Muscles of Lower Limb
Muscles of Trunk (1/2)
No
37.
38.
39.
40.
41.
42.
43.
44.
45.
46.
47.
48.
49.
50.
51.
52.
53.
54.
55.
56.
57.
58.
Title
Muscles of Trunk (2/2)
Physiological anatomy and electrical properties of skeletal muscle
General aproach to Rheumatic Diseases
Introduction to muskuloskeletal system radiology and the radiologic anatomy of
extremities
Physical Examination of the Locomotor System
Introduction to the Biomechanics of the Musculoskeletal System
Mechanism of contraction and relaxation, Molecular Characteristics of theContractile
Filaments
Skeletal-Muscle EnergyMetabolism,Motor unit, Mechanics of Single-FiberContraction
Physical Examination of the Locomotor System in childhood
Drugs Effecting Neuromuscular Transmission
NSAIDs (1/2)
NSAIDs (2/2)
Epidemiology of Rheumatic Diseases
Laboratory Evaluation of Rheumatic Diseases
The Evaluation of Locomotor System Pains
Arthritis in Childhood I
Arthritis in Childhood II
General Approach to the Fractures and Dislocations I
Physical Medicine and Rehabilitation in Locomotor System
General Approach to the Fractures and Dislocations II
Skeletal muscle relaxants and spasmolytics (1/2)
Skeletal muscle relaxants and spasmolytics (2/2)
Course 2.2: Cardiovascular System
Chair:
Prof. Dr. Gülderen Şahin, Physiology
Phone: +902124143000/21614-22572
E-mail: sahing@istanbul.edu.tr
Secretary:
+902124143000/21572
Vice Chairs:
Prof. Dr. Zeki Öngen, Cardiology
Prof. Dr. Ercan Tanyeli, Anatomy
Members:
Prof. Dr. Funda Öztunç, Pediatrics
Prof. Dr. Öner Süzer, Pharmacology
Semester:
3
Credit of Course:
14
14
Lecture (hour)
Practice (hour)
Proportion (%)
Anatomy
13
14
16
Biochemistry
2
2
2
Pediatrics
7
0
6
Infectious Diseases
1
0
1
Pharmacology
26
0
20
Physiology
22
8
20
8
2
7
Internal Medicine
1
0
1
Cardiovascular Surgery
2
0
2
Cardiology
22
0
17
Nuclear Medicine
2
0
2
Pathology
6
4
6
112
30
100
Total
Course content
Course aims
Learning
outcomes
Teaching
methods and
strategies
Cardiovascular System course provides information about the normal structure,
development and functions, system-related diseases, etiology, symptoms, basic
clinical and laboratory findings, diagnostic methods for Cardiovascular System and
drugs used for related diseases.
Teaching function, structure, development and physiopathology of Cardiovascular
System, and basic clinical and laboratory diagnostic methods, drugs used for
related diseases.
By the end of Cardiovascular System course the students should be able to:
Describe anatomical structures,
Describe development and embryonic origins of cardiovascular system
Describe histological structure,
Describe Regulatory Mechanism of Cardiovascular System
Describe etiopatogenesis, symptoms, clinical and laboratory findings of
cardiovascular system diseases.
Describe diagnostic imaging modalities for investigation of the cardiovascular
system
List the treatment options for cardiovascular system diseases.
Describe the effects, mechanisms of action, pharmacokinetics, side effects
and interactions of the drugs used in the treatment of diseases of the
cardiovascular system
Describe pharmacology of the autonomic nervous system and autocoids
Lectures, clinical and laboratories, homework, demonstration.
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
30.
31.
32.
33.
34.
35.
36.
37.
38.
39.
40.
41.
42.
43.
44.
45.
46.
47.
48.
49.
50.
51.
52.
53.
54.
55.
Title
Introduction to Systemic Anatomy, Circulatory System
General Anatomy of Autonomic Nervous System
Morphology of Heart
Vessels of Heart
Autonomic nervous system (1/2)
Autonomic nervous system (2/2)
Introduction to autonomic nerve system and neurotransmission (1/2)
Introduction to autonomic nerve system and neurotransmission (2/2)
Nerves of Heart and Pericardium
Arteries: Head-Neck and Upper Limb Artreries
Electrical activity of the heart, spread of excitation
Parasympathomimetics and cholinesterase inhibitors and reactivators (1/2)
Arteries of Thorax and Abdomen
Arteries of Pelvis and Lower Limb
Sinus rhythm, mechanism of abnormal rhythm production
Parasympathomimetics and cholinesterase inhibitors and reactivators (2/2)
Parasympatholytics and ganglion blockers (1/2)
Parasympatholytics and ganglion blockers (2/2)
Veins of Head-Neck and Upper Limb
Sympathomimetic drugs (1/2)
Sympathomimetic drugs (2/2)
Sympatholytic drugs: Alpha adrenoceptor blockers (1/2)
Sympatholytic drugs: Alpha adrenoceptor blockers (2/2)
Sympatholytic drugs: Beta adrenoceptor blockers (1/2)
Sympatholytic drugs: Beta adrenoceptor blockers (2/2)
Veins of Thorax, Abdomen, Pelvis and Lower Limb
Circulatory System, Adult and Fetal Circulation
Antiarrhythmics (1/2)
Antiarrhythmics (2/2)
Lymphatic Organs and Structures, Lymphatic Circulation
Spread of cardiac excitation through atria and ventricle muscle
Circulatory System Histology (1/4)
Mechanical events of the heart, cardiac cycle
Pressure and volume changes in the atria and ventricles, Heart sounds
Factors controling cardiac output, stroke work and O2 consumption of the heart
Electrocardiogram (1/2): bipolar limb leads, cardiac vector
Lymphatic Vessels, Regional Lymph Nodes
Electrocardiogram (2/2): unipolar limb leads, cardiac axis
Physiology of the circulation: Hemodynamics of circulation
Arterial and arteriolar circulation, arterial pressure and arterial pulse
Histamine agonist and antagonists
Serotonine agonist and antagonists
Capillary circulation, Lymphatic system and edema formation
Symptoms in cardiology (1/2)
Cardiovascular System Embryology (1/4)
Angiotensins, Kinins, Nitric oxide
Symptoms in cardiology (2/2)
Cardiovascular System Examination
Cynosis
Eicosanoids (1/2)
Eicosanoids (2/2)
No
56.
57.
58.
59.
60.
61.
62.
63.
64.
65.
66.
67.
68.
69.
70.
71.
72.
73.
74.
75.
76.
77.
78.
79.
80.
81.
82.
83.
84.
85.
86.
87.
88.
89.
90.
91.
92.
93.
94.
95.
96.
97.
98.
99.
100.
101.
102.
103.
104.
105.
106.
107.
108.
109.
110.
111.
Title
Edema
Edema
Venous circulation and factors effecting venous circulation
Examination of arterial and venous disease
Local control of blood flow by tissues
Neural regulation of the circulation and rapid control of arterial pressure
Inspection and palpation of precordium
Auscultation of the heart (1/2)
Auscultation of the heart (2/2)
Long -term regulation of arterial pressure, regulation of blood pressure during exercise
Cyspnea-Chest Pain
Introduction to cardiac radiology
Congenital acyanotic heart defect
Valvular heart disease
Infective endocarditis Etiopathogenesis and laboratory findings
Congenital Syanotic Heart Disease
Basics of electrocardiogram (1/2)
Basics of electrocardiogram (2/2)
The ECG of conduction disturbances
Congenital heart disease
Infective endocarditis and valvular heart disease
Coronary circulation
Specific circulation (1/2)
Infective endocarditis
Measurement of blood pressure and concept of hypertension (1/2)
Measurement of blood pressure and concept of hypertension (1/2)
Antihypertensives (1/2)
Atherosclerosis and risk factors
Hypertension in children
The ECG of supraventricular arrhythmias
Antihypertensives (2/2)
Specific circulation (2/2)
The ECG of ventricular arrhythmias
Biochemistry of endothelial cells
Endothel function, atherosclerosis, types of anevrisms
Chronic ischemic heart disease
Physiologic mechanisms of shock
Hypolipidemic drugs
Clinical laboratory tests in cardiac disease
Acute coronary syndromes
Antianginals and peripheral vasodilators (1/2)
Antianginals and peripheral vasodilators (2/2)
Pathogenesis of ischemic heart disease and Myocardial infarction
Myocard perfusion scintigraphy
Circulatory parameters in Heart failure
Physiopathology of heart failure
Heart failure
Shock
Treatment of heart failure
Cardiomyopathies
Myocardial diseases, cardiomyopathies, myocarditis, pericarditis
Lymphoscintigraphy and Gamma Probe applications
Pericard diseases
Introduction to cardiovascular surgery
Course 2.3: Respiratory System
Chair:
Prof. Dr. Nermin Yelmen, Physiology
Phone: +902124143000/21612
E-mail: nermink@istanbul.edu.tr
Secretary:
+902124143000/21572
Vice Chairs:
Prof. Dr. Gül Öngen, Pulmonary Medicine
Prof. Dr. Ali İhsan Soyluoğlu, Anatomy
Members:
Prof. Dr. Büge Öz, Pathology
Prof. Dr. Akif Turna, Thoracic Surgery
Semester:
3
Credit of Course:
8
8
Lecture (hour)
Practice (hour)
Proportion (%)
Anatomy
4
4
10
Pediatrics
2
0
3
Infectious Diseases
1
0
2
Pharmacology
6
0
10
Physiology
11
4
21
Thoracic Surgery
1
0
2
Pulmonary Medicine
14
0
22
4
2
8
Otorhinolaryngology
1
0
2
Nuclear Medicine
1
0
2
Pathology
8
2
15
Radiodiagnostics
2
0
3
Toplam / Total
55
12
100
Course content
Course aims
Learning
outcomes
Teaching
methods and
strategies
Respiratory System course provides knowledge about the normal structure,
development and functions, system-related diseases, etiology, symptoms, basic
clinical and laboratory findings, diagnostic methods for Respiratory System and
At the end of the Course students should gain knowledge of the function,
structure, development and physiopathology of Respiratory System, and basic
clinical and laboratory diagnostic methods, drugs used for related diseases.
At the end of Respiratory System course the students should be able to:
2. Describe development and embryonic origins of respiratory system
3. Describe histological structure,
4. Describe functions of respiratory system and regulation of respiration
5. List the normal values of the arterial blood gases
6. Describe lung volumes and capacities and evaluate them
7. Describe etiopatogenesis, symptoms, clinical and laboratory findings of
respiratory system disorders.
8. Describe diagnostic imaging modalities for investigation of the respiratory
system
9. List the treatment options for diseases of the respiratory system.
10. Describe the effects, mechanisms of action, pharmacokinetics, side effects
respiratory system.
Lectures, clinical and laboratory practices, homework, demonstration.
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
30.
31.
32.
33.
34.
35.
36.
37.
38.
39.
40.
41.
42.
43.
44.
45.
46.
47.
48.
49.
50.
51.
52.
53.
54.
55.
Title
Respiratory System: Nose, Paranasal Sinuses
Physiology of Respiratory System, Mechanics of breathing
The Respiratory System, Conducting portion
The Respiratory System , Larenx and Trachea Histology
Larynx, Trachea and Bronchi
Inspiratory and expiratory mechanisms
Pressure-Volume changing, compliance
Histology of the alveoli and the Lung
Lungs and Pleura, Mediastinum
Lung volume and capacities
Respiratory System Development
Clinical Anatomy of Respiratory System
The radiologic anatomy of Respiratory System-I
Ventilation-perfusion relationship: V/P ratio
The radiologic anatomy of Respiratory System-II
Lung function tests: Diffusion capacity
History and Symptoms in Pulmonary Diseases (dyspnea, chest pain)
Cellular values of respiratory system
Gases Transport in the Blood, Oxygen Carriage
Examination of the chest (pulmonary function tests)
Pathology of upper airways
Anamnesis in Upper Respiratory Tract Diseases
Physical examination of thorax and lung (inspection, palpation)
Carbondioxide transport and Respiratory quotient
Atelectasis, diseases of vascular origin in lung
Chemical regulation and respiratory regulation in sleep
Drugs used in Upper Respiratory Tract Diseases
Physical examination of thorax and lung (percussion oscultation)
Pathology of Obstructive pulmonary diseases
History and Symptoms in Pulmonary Diseases (cough, sputum, hemoptysis)
Obstructive pulmonary diseases
Respiratory physiology at high and low pressures
Bronchodilators ve other antiastmatic drugs
Development of respiratory system in children
Examination of the chest (radiology)
Restrictive pulmonary diseases
Cough, Stridor, wheezing
Other Laboratory methods
Approach to respiratory system infection in adults
Bronchodilators ve other antiastmatic drugs
Pulmonary infections
Antitussives, expectorants, mucolytics, surfactants
Lung tumors
Pneumonia
Drugs used in Lung Cancer
Lung tumors II, plevral diseases
Lung cancer
Symptoms and signs in pulmonary surgery
Nuclear Medicine in Respiratory System
Pulmonary tuberculosis
Drugs used in Lung Tuberculosis
Environmental Physiology
Tuberculosis
Smoking and enviromental lung diseases (1/2)
Smoking and enviromental lung diseases (2/2)
Course 2.4: Hematopoietic System, Immunology,
Microbiology
Chair:
Prof. Dr. Gökhan Aygün, Microbiology and Clinical Microbiology
Phone: +902124143000/22754 Secretary:
E-mail: gokhanaygun67@yahoo.com
+902124143000/21647
Vice Chairs:
Prof. Dr. Teoman Soysal, Internal Medicine
Prof. Dr. Yıldız Camcıoğlu, Pediatrics
Üyeler (Members)*:
Prof. Dr. Aydın Barlas, Pharmacology
Prof. Dr. Gönül Şimşek, Physiology
Semester:
4
Credit of Course:
16
16
Lecture (hour)
Practice (hour)
Proportion (%)
Biochemistry
6
2
5
Pediatrics
6
0
5
Pharmacology
12
0
8
Physiology
9
4
8
General Surgery
2
0
2
3
2
3
Internal Medicine
20
0
13
47
6
35
Nuclear Medicine
1
0
1
Pathology
9
4
8
Medical Education
0
36
12
Total
115
54
100
Course content
Hematopoietic System, Immunology, Microbiology course provides knowledge and
skills about the normal structure, development and functions, system-related
diseases, etiology, symptoms, basic clinical and laboratory findings, diagnostic
methods for Hematopoietic System, Immunology, Microbiology and drugs used for
related diseases.
Also this course covers a clinical skills module (patient encounter and
communication skills, ethics, patient transportation, basic clinical procedures, hand
hygiene, the prevention of nosocomial infections and, CPR)
Course aims
By the end of the this Course students should learn function, structure,
development and physiopathology of Hematopoietic System, Immunology,
Microbiology, and basic clinical and laboratory diagnostic methods, drugs used for
related diseases.
By the end of the Hematopoietic System, Immunology, Microbiology course the
students should be able to:
1. Describe basic subjects of microbiology, characteristics of viruses
2. Describe the diseases of these systems
3. Describe the etiopatogenesis of hematopoietic and immunologic systems
diseases.
4. Describe the laboratory findings of hematopoietic and immunologic systems
diseases.
5. List the treatment options for hematopoietic and immunologic systems
diseases
6. Describe the factors, diagnosis and treatment options of viral and fungal
infections
7. Be aware of the importance of professional and ethical behaviour in the act of
medical care
Learning
outcomes
Teaching
methods and
strategies
Lectures, laboratory practices, basic clinical skills training, homework
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
30.
31.
32.
Title
Organs and tissues of immune system -I
Organs and tissues of immune system -II
Organs and tissues of immune system -III
Naturel immune system
Introduction to clinical microbiology
Phagocytes and inflammation
Cell structure and classification of medically important bacteria
Bacterial pathogenesis
Bacterial genetics, diagnosis, cultivation
Endotoxins and exotoxins
Sterilisation, Disinfection, and Antisepsis (1/2)
Sterilisation, Disinfection, and Antisepsis (2/2)
Colonisation, infection and infectious diseases
Innate immune response
Cell mediated immunity
Introduction to medical mycology
Dermatophytes, other superficial mycoses, subcutaneous mycoses
Mechanisms of specific host defense
Candida, Cryptococcus neoformans and other yeasts
Complement System
Antigens and antigen recognition
Humoral immunity
Dimorphic fungi
Opportunistic mycoses and Pneumocystis
Mycotoxins
Antifungal chemotherapy
Immun receptors and signal transduction
Acquired immune system
Cytokines and interferons
Active and passive immunity
Immunity to fungi
Antifungals
No
33.
34.
35.
36.
37.
38.
39.
40.
41.
42.
43.
44.
45.
46.
47.
48.
49.
50.
51.
52.
53.
54.
55.
56.
57.
58.
59.
60.
61.
62.
63.
64.
65.
66.
67.
68.
69.
70.
71.
72.
73.
74.
75.
76.
77.
78.
79.
80.
81.
82.
83.
84.
85.
86.
87.
88.
Title
Classification, cultivation and identification of viruses
Prevention and treatment of viral infections
Immunotolerance
Dysenfectans and antiseptics
Herpesviruses 1
Herpesviruses 2
Active Immunization
Assessment of functional immune responses
Adenoviruses and parvoviruses
Poxviruses
Prions
Hepatitis viruses 1
Primary immune deficiencies
Laboratory methods in immunology -1
Laboratory methods in immunology -2
Autoimmunity
Autoimmune diseases
Transplantation immunology
Hepatitis viruses 2
Hepatitis viruses 3
Picornaviruses
Papillomaviruses and polyomaviruses
Basic principles of transplantation surgery
Paramyxoviruses and Rubella virus
Orthomyxoviruses and coronaviruses
Rhabdoviruses
Arboviruses
Retroviruses 1/2
Retroviruses 2/2
Arenaviruses, Hantaviruses and filoviruses
Human Cancer Viruses
Antiviral drugs
Immunopharmacology
Microorganisms and autoimmunity
Viral pathogenesis and immunology of viral infections
Biochemistry of red blood cells and white blood cells
History taking characteristics in Hematopoietic System Disorders
Physical Examination characteristics in Hematopoietic System Disorders
Hypersensitivity Type III, IV
Synthesis of heme and porphyrias
Peripheral blood and bone marrow examination
Hematopoetic System
Hematopoesis –I: mechanisms of Eritropoiesis
Hematopoesis –II: mechanisms of Leukopoiesis and types of leukocytes
Catabolism of heme and hyperbilirubinemia
Anemia in children
Hematopoesis –III: mechanisms of thrombopoiesis
Iron metabolism and hemoglobin
Hemostasis,Coagulation and fibrinolysis mechanisms
The blood groups
Classification of anemias in adults
Biochemical evaluation of anemias
Iron deficiency anemia
Antianemic drugs
Introduction to chronic myeloproliferative disorders Polystemia vera and essential
thrombocytemia
Laboratory diagnosis in disorders of hemoglobin metabolism
No
89.
90.
91.
92.
93.
94.
95.
96.
97.
98.
99.
100.
101.
102.
103.
104.
105.
106.
107.
108.
109.
110.
111.
112.
113.
114.
115.
Title
General principles of hemolytic anemias
Hemostatic mechanisms and routine tests for hemorrhagic diathesis-2
Hemostatic mechanisms and routine tests for hemorrhagic diathesis-1
Haemostatic drugs
Acquired hemolytic anemias
Bleeding tendency
Acute leukemias
Anti-thrombocyte, anticoagulant, thrombolytic drugs (1/2)
Anti-thrombocyte, anticoagulant, thrombolytic drugs (2/2)
Hereditary hemolytic anemias
Hodgkin lymphoma
Aplastic anemia and myelodysplastic syndrome
Surgical bleeding and hemostasis
Megaloblastic anemias
Non Hodgkin lymphoma
Pancytopenias and aplastic anemia
Chronic myeloproliferative diseases
Chronic myeloid leukemia, idiopatic myelofibrosis
Antineoplastics (1/2)
Antineoplastics (2/2)
Clinical characteristics of lymphomas
Pathology of the diseases of spleen
Lymphadenopathies
PET scintigraphy in Hematologic Malignancies
Plasma cell dyscrasias
Splenomegaly
Stem cell concept and its applications
Course 2.5: Gastrointestinal System
Chair:
Prof. Dr. Arzu Seven, Biochemistry
Phone: +902124143000/21478 Secretary:
E-mail: arzu_seven@hotmail.com
+902124143000/21514
Vice Chairs:
Prof. Dr. Serdar Yüceyar, General Surgery
Prof. Dr. Ahmet Merih Dobrucalı, Internal Medicine
Members:
Prof. Dr. Gülderen Şahin, Physiology
Prof. Dr. Ayşe Derya Ertem, Anatomy
Semester:
4
Credit of Course:
14
14
Lecture (hour)
Practice (hour)
Proportion (%)
Anatomy
8
8
8
Biochemistry
25
10
21
Pediatric Surgery
2
0
1
Pediatrics
8
0
5
Infectious Diseases
2
0
1
Pharmacology
4
0
3
Physiology
14
2
10
General Surgery
20
0
14
8
8
8
Internal Medicine
22
0
15
Nuclear Medicine
1
0
1
Pathology
10
4
8
Radiodiagnostics
1
0
1
Medical Education
0
10
4
125
42
100
Total
Course content
Course aims
Gastrointestinal System course provides knowledge and skills about the normal
structure, development and functions, system-related diseases, etiology,
symptoms, basic clinical and laboratory findings, diagnostic methods for
Gastrointestinal System and drugs used for related diseases.
Teaching function, structure, development and physiopathology of Gastrointestinal
System, and basic clinical and laboratory diagnostic methods, drugs used for
related diseases.
Learning
outcomes
Teaching
methods and
strategies
By the end of gastrointestinal system course the students should be able to:
Describe anatomical structures of the gastrointestinal system,
Describe development and embryonic origins of the gastrointestinal system,
Describe histological structure,
Describe function mechanisms.
Describe etiopatogenesis, symptoms, clinical and laboratory findings of
gastrointestinal system diseases.
Describe diagnostic imaging modalities for investigation of the gastrointestinal
system
List the treatment options for gastrointestinal system diseases.
Describe the effects, mechanisms of action, pharmacokinetics, side effects
gastrointestinal system
Lectures, laboratory practices, homework, demonstration
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
30.
31.
32.
33.
34.
35.
36.
Title
Digestion and absorption of carbohydrates
Glycolysis
Digestive System Oral cavity, Tongue
Digestive System Pharynx and Teeth
The citric acid cycle
Metabolism of glycogen
Digestive System Esophagus and Stomach
Digestive System: Introduction, Mouth
Gluconeogenesis and control of blood glucose
The pentose phosphate pathway and other pathways of hexose metabolism
Digestive System Small and Large Intestine
Disorders of carbohydrate metabolism
Digestion and absorption of lipids
Pharynx and Esophagus
Digestive System Accessory glands-I Salivary Glands, Pancreas
Organs Associated with Digestive Tract: Salivary Glands and Pancreas
Biosynthesis of fatty acids
Oxidation of fatty acids and.Ketogenesis
Neural control of gastrointestinal function,enteric nervous system
Mechanical and chemical digestion in the mouth
Metabolism osf acyl Glycerols,sfingolipids and eicozinoids
Lipid transport and storage
Inflammation and neoplastic lesions of oral cavity and salivary glands,anatomic,motor
and inflammatory disorders of esophagus
Saliva secretion and function
Digestive bladder system accessory glands II liver
Cholesterol synthesis, transport and excretion
Disorders of lipid metabolism
Stomach
Digestion of dietary proteins
Amino acid transport and associated hereditary disorders
Mechanism of swallowing and functions of esophagus
Basic rules for stomach motility
Catabolism of proteins and of amino acid nitrogen
Catabolism of proteins and of amino acid nitrogen
Organs Associated with Digestive Tract: Liver and Biliary Ducts
Digestive System Development-I
No
37.
38.
39.
40.
41.
42.
43.
44.
45.
46.
47.
48.
49.
50.
51.
52.
53.
54.
55.
56.
57.
58.
59.
60.
61.
62.
63.
64.
65.
66.
67.
68.
69.
70.
71.
72.
73.
74.
75.
76.
77.
78.
79.
80.
81.
82.
83.
84.
85.
86.
87.
88.
89.
90.
91.
Title
Catabolism of the carbon skeletons of amino acids. Biosynthesis of nonessential amino
acids
Conversion of amino acids to specialized products. Hereditary disorders of amino acid
metabolism
Mechanism and regulation of salivation in stomach
Inhibition of gastric secretion by other post-stomach factors
Laboratory diagnosis in liver diseases
Laboratory diagnosis in liver diseases
Small and Large Intestine
Digestive System Development-II
Biochemical evaluation of gastrointestinal dysfunctions
Biochemical evaluation of pancreatic disorders
Role of pancreas in digestion and regulation of salivation
Production of bile and its role in digestion
Intestinal motility and secretions
Mechanism of regulation of intestinal motility and secretion
Peritoneum
Topographical Anatomy of Abdomen
Gastrointestinal Development
Nuclear Medicine in Gastrointestinal and Hepatobiliary System
History and physical examination in gastrointestinal system
History taking characteristics in gastrointestinal System Disorders
Vomiting
Radiologic examination and anatomy of the abdomen
Surgical symptomatology and diagnosis in diseases of gastrointestinal system
Physical examination of the abdomen
Abdominal Pain
Surgical symptomatology and diagnosis of liver and biliary tract diseases
Abdominal pain
Diarrhea Constipation
Vomiting and gastrointestinal bleeding in childhood
Acute abdomen (symptomatology and diagnosis)
Dsyphagia
Abdominal and Lymphois System
Emetics, antiemetics, prokinetics
Acute appendicitis (symptomatology and diagnosis)
Gastroesophageal reflux disease
Icterus
Abdominal pain in childhood
Gastrointestinal bleeding in surgery
Gastritis, H pylori and related diseases
Abdominal masses
Intestinal obstruction
Peptic ulcer disease
Hepatomegaly - Ascites
Diarrhea, constipation and meteorism
Drugs to treat peptic ulcer
Metabolic homeostasis in fasting and fed state
Splenomegaly
Benign and malignant diseases of anus and perianal region
Acute cholecystitis (symptomatology and diagnosis)
Malabsorption: Symptoms and classification
Infectious diseases of small intestine and colon
Pathology of esafagus diseases
Pathology of stomach diseases
Inflammatory bowel disease: Ethiopathogenesis, and clinical presentation
Hernias
No
92.
93.
94.
95.
96.
97.
98.
99.
100.
101.
102.
103.
104.
105.
106.
107.
108.
109.
110.
111.
112.
113.
114.
115.
116.
117.
118.
119.
120.
121.
122.
123.
124.
125.
Title
Colon motility, digestion in colon, and defecation
Acute pancreatitis (symptomatology and diagnosis)
Gastrointestinal diverticular disease
Bile Stones; Ethiopathogenesis, clinical presentation andlaboratory findings
Surgical equipments (drains, catheters, suture materials)
Digestans, choletics, cholagogues, cholelithics, other drugs effecting on GIS
Cholestasis and cholestatic liver disease
Basic mechanisms of absorbtion; transport and storage of absorbed carbonhyrates,
lipids and proteins
Chronic pancreatitis
Stomach tumors
Viral hepatitis
Basic mechanism of absorption,transport and storage of electrolytes and vitamins
Medical approach to gastrointestinla bleeding
GI symptoms in systemic diseases and systemic findings in GI diseases
Idiopathic inflammatory bowel diseases, vascular Disorders of bowel
Tumors of small and large bowels and appendix
History taking and physical examination characteristics in hepatic and bile duct disease
Gastrointestinal tumors (upper)
Laboratory findings and diagnostic methods in hepatic and bile duct disorders
Jaundice, approach to patient with jaundice
Gastrointestinal tumors (lower)
Pancreas (exocrine) pathology
Chronic liver disease / Cirrhosis
Viral Hepatitis
Approach to infectious diarrheae in adults-Clinical features and Diagnosis
Laxatives, purgatives, antidiareics, oral rehidratation salts
Gastrointestinal system injuries
Hepatobiliary and pancreatic tumors
Approach to patient with ascites
Surgical nutrition and metabolism
The principles of basic surgical techniques
Intraabdominal infections (peritonitis and abscess)
Cirrhosis
Liver tumors
3rd Year Courses
Course 3.0: Introduction to Internal Medicine Practice
Chair:
Prof. Dr. Aydın Tunçkale, Internal Medicine
Phone:
E-mail:
+902124143000/22412-22938
aydintunckale@gmail.com
Secretary:
+902124143000/21629
Vice Chairs:
Prof. Dr. Zeki Öngen, Cardiology
Assoc. Prof. Dr. Derya Uğurlu Uludüz, Neurology
Members:
Prof. Dr. Benan Müsellim, Pulmonary Medicine
Assoc. Prof. Dr. Burhan Engin, Dermatology
Semester:
5
Credit of Course:
2
2
Lecture (hour)
Practice (hour)
Proportion (%)
Dermatology
0
2
4
Infectious Diseases
1
0
4
1
2
7
Pulmonary Medicine
2
4
14
Internal Medicine
6
10
39
Cardiology
3
6
21
Neurology
1
4
11
Total
14
28
100
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
Title
Interviewing and history taking skills
History taking and general apperance examination
General apperance and vital signs
History taking and general apperance examination
Physical examination of the head, face and neck. Examination of the lymp nodes
Respiratory system symptoms (cough, dyspnea, haemopthysis)
Physical examination of the respiratory system
Cardiac symptoms
Physical examination of the cardiovascular system
Gastroenterological symptoms-1 (jaundice, Haematemesis, melena, ascites)
Gastroenterological symptoms-2 (dyspepsia, constipation, diarrhea, dysphagia)
Dermatological examination
Neurologic System Examination
Physical examination of the locomotor system
Evaluating the patient with fever and rash
Physical examination of the locomotor system
Course 3.1: Nerve System and Sensory Organs
Chair:
Prof. Dr. Ertan Yurdakoş, Physiology
Phone: +902124143000/21609 Secretary:
E-mail: ertanyurdakos@mynet.com
+902124143000/21572
Vice Chairs:
Prof. Dr. Sibel Ertan, Neurology
Prof. Dr. Ayşe Derya Ertem, Anatomy
Members:
Prof. Dr. Aydın Barlas, Pharmacology
Assoc. Prof. Dr. Emine Elif Güzel, Histology
Semester:
5
Credit of Course:
15
15
Lecture (hour)
Practice (hour)
Proportion (%)
Anatomy
32
14
24
Biochemistry
1
0
1
Dermatology
2
0
2
Infectious Diesases
5
0
3
Pharmacology
18
0
11
Physiology
30
10
21
Opthalmology
2
0
2
Histology
18
2
11
Otorhinolaryngology
2
0
2
Neurology
13
0
8
Neurosurgery
3
0
2
Nuclear Medicine
1
0
1
Pathology
12
4
9
Pediatrics
1
0
1
Radiology
2
0
142
30
2
100
Total
Course content
This course provides information about the normal structure,development and
functions,system related diseases,etiology,symptoms basic clinical and laboratory
findings, diagnostic methods and also drugs used for the treatment of related
diseases of the nerve system and sensory organs
Course aims
Learning
outcomes
Teaching
methods and
strategies
The aim is to teach
the basic information about the functions, structure, development and
physiopathology of Nerve System and Sensory Organs, and basic clinical and
laboratory diagnostic methods, drugs used for the treatment of related diseases
At the end of Nerve System and Sensory Organs course the students should be
able to:
1. Describe the anatomical structures,
2. Describe the development and embryonic origins,
3. Describe the histological structures,
4. Describe the functional mechanisms,
5. Describe the sysmptoms, etiopathogenesis and histopathology of the diseases,
6. Describe the imaging techniques,
7. Describe the treatment methods,
8. Describe the drugs,their pharmacology,side effects and drug interactions for
the treatment of related diseases of the nervous system and sensory organs
Lectures,laboratory practices,clinical practices and demonstrations.
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
30.
31.
32.
33.
34.
35.
Title
Neuroanatomy General View
Central Nervous System; Peripheral Nervous System: Definition
Synaptic and junctional transmission: Electrical and chemical events
Development of Head and Neck (1/3)
General characteristics of synapses and reflexes
Monosynaptic reflexes- The strech reflex
Meninges
Prosencephalon
General histology of nervous system
Polysynaptic reflexes: The withdrawal reflex
Subcortical gray matter
Subcortical white matter
The protection of the Central Nervous System (CNS): Physiologic characteristics of
cerebro-spinal-fluid and the blood-brain-barrier
Histology of medulla spinalis, brain stem and peripheral nervous system
Initiation of impulses in sense organs and the antero lateral system
The consideration of Sensory information: cuteneous, deep and visceral sensation
Histology of cerebellum and cerebrum
Diencephalon
Early development of neural tube- Development of medulla spinalis and peripheral
nervous system
Development of brain stem, cerebellum and cerebrum
The physiologic characteristics of the pain
Mesencephalon
Pons
Medulla oblongata
Cerebral Cortex
Congenital malformations of the nervous system
Thalamus and The Reticular Formation
EEG,Sleep and Evoked Potentials
Cerebellum
Corticospinal and Corticobulber Systems
Vessels of Central Nervous System I
Vessels of Central Nervous System II
Histology of the skin
No
36.
37.
38.
39.
40.
41.
42.
43.
44.
45.
46.
47.
48.
49.
50.
51.
52.
53.
54.
55.
56.
57.
58.
59.
60.
61.
62.
63.
64.
65.
66.
67.
68.
69.
70.
71.
72.
73.
74.
75.
76.
77.
78.
79.
80.
81.
82.
83.
84.
85.
86.
87.
88.
89.
90.
91.
Title
Posture Regulating Systems
Brain Ventricles and CSF (Cerebrospinal Fluid)
Spinal cord Anatomy
Medullary Mechanisms and The Decebrate Rigiditiy
Posture and The Vestibular System
Midbrain
Spinal cord: Ascending Tracts
Spinal cord: Descending Tracts
The Basal Ganglia
Cranial nerves
Cranial nerves
The Cerebellum
Interaction of The Cerebellum and The Basal Ganglia in The Control of The Motor
Functions
The Speech Formation and The Lateralization in The Brain
Association Areas of The Cerebral Cortex
Cranial nerves
Spinal Nerve Plexuses I
Spinal Nerve Plexuses II
The Hypothalamus
The Limbic System
Autonomic Nervous System
Autonomic Plexuses I
The Physiology of Learning and Memory
Histology of the skin
Biochemistry of Neurotransmission
Autonomic Plexuses II
The physiologic characteristics of hearing
The physiologic mechanisms of central audition
Autonomic Innervation of organs
Sense organs
Development of skin
Ear I
Ear II
Taste and Smell Sensations
Histology of Ear
Skin; Tongue; Nose
Eye I
Eye II
Development of Ear
Histology of Eye (1/2)
Histology of Eye (2/2)
Vision, Photoreceptor Mechanisms
Responses in the Visual Pathways
Development of Eye
Image forming mechanism
I Introduction to anomalies, edema CNS pathology
Red Eye
Transmission of pain, inflammation and their mediators
Neurological examination 1/2
Vascular disease of CNS travma
The symptoms in ocular disease
Introduction to central nervous system pharmacology
Encephalitis and brain absces
Anxiolytic, Sedative and Hypnotic drugs
Neurological examination 2/2
Antidepressant drugs
No
92.
93.
94.
95.
96.
97.
98.
99.
100.
101.
102.
103.
104.
105.
106.
107.
108.
109.
110.
111.
112.
113.
114.
115.
116.
117.
118.
119.
120.
121.
122.
123.
124.
125.
126.
127.
128.
129.
130.
131.
132.
133.
134.
135.
136.
137.
138.
139.
140.
141.
142.
Title
Antimanic drugs
Frontal and temporal lobes; Anatomical localization and clinical findings
Mental Retardation
Rabies: Clinical manifectations and prophylaxis
Parietal and occipital lobes; Anatomical localization and Clinical findings
CNS Tumors
CNS Tumors
Cerebellum ;Anatomical localization and clinical findings
Head and Neck Radiology
Menengitis and encephalitis
Degenerative and demyelinazing disesaes
CNS stimulants and psychotomimetic drugs
Clinical findings of cranial nerve diseases
Tetanus: Clinical presentations and prophylaxis
CNS Radiology
Basal ganglia; Anatomical localization and clinical findings
Spinal cord; Anatomical localization and clinical findings
Viral Encephalitis
Alcohols and alcohol intoxication
Peripheric nerve system
Drugs used in the treatment of Alzheimer‟s disease
Drugs used in the treatment of Parkinson‟s disease
Brain stem ; Anatomical localization and clinical findings
General anesthetics: inhalation anesthetics
Inflammatory skin diseases I
Inflammatory skin Diseases II
Central nervous system developmental abnormalities and clinical findings
General anesthetics: intravenous anesthetics
Clinical findings in peripheral nerve diseases
Principles of dermatologic diagnosis
Eye Pathology
Clinical findings in neuromuscular junction and muscle disease
Local anesthetics
Symptom and Practice in Dermatology
Opioid analgesics and antagonists (1/2)
Opioid analgesics and antagonists (2/2)
Tumoral Lesions of skin
Clinical diagnosis in chronic menengitis
Sleep and wakefulness
Introduction to Neurosurgery
Coma and delirium
Antiepileptic drugs (1/2)
Antiepileptic drugs (2/2)
Nuclear Medicine in Central Nervous System
Raised Intracranial Pressure
Vertigo and Tinnitus
Vertigo and Tinnitus
Clinical diagnosis in Acute menengitis
Neurosurgical Approach to Neurological Symptoms: From Symptom to Diagnosis (Case
Discussion)
Neuroleptic drugs (1/2)
Neuroleptic drugs (2/2)
Course 3.2: Genitourinary System
Chair:
Prof. Dr. Altay Gezer, Gynecology and Obstetrics
Phone: +902124143000/21406 Secretary:
E-mail: agezer@superonlıne.com
+902124143000/21539
Vice Chairs:
Prof. Dr. Mehmet Rıza Altıparmak, Internal Medicine
Prof. Dr. Mehmet Seven, Medical Genetics
Members:
Prof. Dr. İsmail Seçkin, Histology
Prof. Dr. Şennur İlvan, Pathology
Semester:
5
Credit of Course:
13
13
Lecture (hour)
Practice (hour)
Proportion (%)
Anatomy
7
14
9
Biochemistry
3
4
3
2
0
2
Pharmacology
6
0
4
Physiology
12
2
9
General Surgery
2
0
2
Histology
12
6
10
Internal Medicine
9
0
6
Gynecology and Obstetrics
23
0
15
Nuclear Medicine
1
0
1
Pathology
14
4
11
Pediatrics
4
0
3
Radiology
3
0
2
Medical Genetics
28
0
19
Urology
6
0
4
132
30
100
Infectious Diseases
Total
Course content
The course provides the information about the normal structure, development and
function of the genitourinary system. System related disaeses are reviewed to
teach the basic knowledge on etiology, physiopathology and to gain basic skills on
signs and symptoms,diagnostic methods, laboratory investigation and treatment.
Course aims
Learning
outcomes
Teaching
methods and
strategies
The course aims to teach the information about the normal structure, development
and function of the genitourinary system. System related disaeses are reviewed
aiming to teach the basic knowledge on etiology, physiopathology and to gain
basic skills on signs and symptoms,diagnostic methods, laboratory investigation
and treatment
By the end of the course, students should be able to;
9. Describe the anatomical structures,
10. Describe the embriological origins and the development
11. Describe the histological pattern
12. Describe the fuctions and mechanisms of the genitourinary system.
13. Describe the etiology, physiopathology of the diases of the genitourinary
system and the pathological changes due to related diseases.
14. List the basic clinical signs and symtoms of the diseases of the genitourinary
system, the diagnostic tests (radiological and biochemical etc.) and the results
of this tests
15. List the basic treatment of diseases of the genitourinary sysytem, drugs used in
the treatmet (concerning the action, mechanism of action, pharmacokinetics,
adverse effects, drug and drug relations).
Lectures, clinical and laboratory practical workshop, question & answer,
demonstrations
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
30.
31.
32.
33.
Title
Urinary and Genital Systems: Introduction
The Neurohypophysis and ADH
Gonad Hormones: Male
Histology of Urinary System
Endocrine Physiology: The male gonad hormones
Kidneys, Ureters,
Gonad Hormones: Female
Endocrine Physiology: The female gonad hormones
Male reproductive organs I
Biochemical evaluation in renal disorders
Endocrine Physiology: The physiologic characteristics of the menstruel cycle
Male reproductive organs II
Female reproductive organs I
Female reproductive organs II
Histology of Male Genital System
Endocrine Physiology: Pregnancy, labor and lactation
Lactation and fertility control
Perineum
Functions of the Kidneys and Its importance, Physiology of Nephron
Urine Formation by the Kidneys: Glomerular Filtration, Tubular Reabsorption and
Tubular Secretion
Regulation of Glomerular Filtration Rate and Renal Blood Flow
Histology of Female Genital System
Histology of Female Genital System
Development of Urogenital System (1/3)
History taking and physical examination in kidney disease
Renal mechanisms of Urine Dilution and Concentration
Control of Potassium and Sodium Concentration in Extracellular Fluid
Micturition Reflex, Renal Control of Acid-Base Balance
No
34.
35.
36.
37.
38.
39.
40.
41.
42.
43.
44.
45.
46.
47.
48.
49.
50.
51.
52.
53.
54.
55.
56.
57.
58.
59.
60.
61.
62.
63.
64.
65.
66.
67.
68.
69.
70.
71.
72.
73.
74.
75.
76.
77.
78.
79.
80.
81.
82.
83.
84.
85.
86.
87.
88.
89.
90.
Title
Renal anomalies, cystic diseases of kidney
Proteinüria - Hematuria
Gynecologic and obstetric history taking and examination
Urinalysis and its clinical importance
Gene structure and function
Mendelian inheritance
Urologic examination and taking history
Radiology of the Urological System
Non-mendelian inheritance
Glomeruler Diseases Pathogenesis and Histologic Features
Newborn
Oliguria and polyuria
Menstrual cycle and its neuroendocrine control
Urolithiasis
Gonodal Hormones and inhibitors (1/4)
Urological malignancy
Urinary tract infections
Primary GN
Multifactorial - Polygenetic Inheretance
Abnormal uterine bleeding
Secondary GN
Evaluation of renal functions
Chromosome disorders and analysis methods
Urinary System Development
Normal and abnormal variations in genetic structure
Pelvic pain
Tubulointerstitial diseases of kidney
Sexually transmitted diseases
Fluid and electrolyte balance
Fluid and electrolyte imbalance, dehydration
Physiology and disorders of voiding
Urinary system infections and sexually transmitted diseases
Diagnostic methods in molecular genetics
New diagnostic methods in genetics
Vaginal flour and abnormal vaginal discharge
Hydronephrosis, renal stones
Diagnostic tests and methods in obstetrics
Uteruse Pathology
Cytogenetic approach in pretanal and preimplantation genetics
Breast examination and Symptomatology
Renal tumors, urinary bladder carcinoma
Molecular approach in pretanal and preimplantation genetics
Hyper and hypopotassemia
Diagnostic tests and methods in gynecology
Erectile dysfunction
Acid-base balance and its disturbances
Testis pathology :Infertility, congenital anomailes, inflammation and tumors
Human reproduction
Nuclear Medicine in Genitourinary System
Cervical Pathology
Developmental genetics
Assisted reproduction in humans
No
91.
92.
93.
94.
95.
96.
97.
98.
99.
100.
101.
102.
103.
104.
105.
106.
107.
108.
109.
110.
111.
112.
113.
114.
115.
116.
117.
118.
119.
120.
121.
122.
123.
124.
125.
126.
127.
128.
129.
130.
131.
132.
Title
Breast cancer
Screening of invasive and preinvasive lesions
Radiology of the Genital System
Dismorphology and multiple congenital abnormalities
Neural development disorders
Benign and melignant breast diseases
Vaginal and Vulvar Pathology
Fetal Radiology
Hereditary mental retardations and Fragile-X Syndrome
Gynecological cancers
Reproductive stages of women‟s life
Ovarian Pathology
Hyperandrogenism
Fetal and Placental Pathology
Breast Pathology
Chrosomal breakage syndromes
Obesity in obstetrics and gynecology
Diagnosis of pregnancy and prenatal care; screening tests in obstetrics
Microdeletion syndromes
Genetics of metabolic disorders
Cancer genetics
Molecular features of hematopoietic malignancies and genetic diagnosis
Development of fetus and placenta
Maternal changes and adaptation to pregnancy
Hereditary disorders of the cancer
Hereditary disorders of the blood
Premature
Bleeding in pregnancy
Pharmacogenetics, pharmacogenomics and personalized medicine in clinical practice
Effects of teratogens on human health
Normal labor
Effect of genetically modified organisms on human organism
Therapy of genetic disorders and gene therapy
Abnormal labor
Bioinformatics in medical genetics
Breast examination and diseases
Oxytocic drugs
Principles and problems in genetic counseling
Principles of drug use in pregnancy
Ethical and legal problems in medical genetics
Shock in Ob&Gyn
Family planning and contraception
Course 3.3: Topographic Anatomy - Biostatistics Deontology
Chair:
Prof. Dr. M. Yakup Tuna, Anatomy
Phone: +902124143000/21563 Secretary:
E-mail: ctfanatomi@istanbul.edu.tr
+902124143000/21563
Vice Chairs:
Prof. Dr. Gürsel Çetin Forensic Medicine
Prof. Dr. Hatun Hanzade Doğan, Deontology and History of Medicine
Members:
Prof. Dr. Mustafa Şükrü Şenocak, Biostatistics
Assoc. Prof. Dr. Nurver Turfaner, Primary Care
Semester:
6
Credit of Course:
8
8
Lecture (hour)
Practice (hour)
Proportion (%)
Forensic Medicine
15
0
17
Primary Care
7
0
8
Anatomy
34
14
45
Biostatistics
12
0
13
Deontology and History of Medicine
11
0
12
Clinical Practices
0
12
5
Total
79
26
100
Course content
Course aims
Learning
outcomes
Teaching
methods and
strategies
Topographic anatomy, forensic medicine, clinical biostatistics, medical ethics,
primary care.
Topographic Anatomy - Biostatistics - Deontology course provides knowledge
about topographic structures, forensic Medicine,ethics, clinical biostatistics, and
primary care.
By the end of this course the students should be able to:
16. Describe the topographic anatomy of human body,
17. Describe basic concepts of forensic medicine,
18. Have information about medical ethics,
19. Hold an opinion about biostatistics methods.
20. Describe the essentials of primary care.
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
30.
31.
32.
33.
34.
35.
36.
37.
38.
39.
40.
41.
42.
43.
44.
45.
46.
47.
48.
49.
50.
51.
52.
53.
54.
55.
Title
Introduction to the Aims and Significance of Medical and Clinical Ethics from a Global
Perspective
Upper Extremity
Shoulder
Introduction to Clinical Biostatistics
Legal responsibilities of physicians
Arm and forearm
History and Essentials of Primary Care, Global Applications and Applications in Turkey
Variables and Basic Design of Clinical Trials
Lower extremity
Hip and thigh
Clinical Problem Solving in Primary Care
Hands
Introduction to Theoretical and Applied Ethics
Back: General anatomy
Basics of death
Observation of Beneficence and Nonmaleficence During Clinical Practice
Foot
Periodic Health Examinations
Probability Evaluation, Bivariate and Multivariate Analysis
Knee and leg
Wounds
Pediatric death
Back: Clinical anatomy
Relative Risk Measures – OR, RR (1/2)
Upper Extremity: Clinical Anatomy
Lower Extremity: Clinical Anatomy
Justice and Allocation of Health in Clinical Practice
Approach to Hyperlipidemia in Primary Care
Approach to Hypertension in Primary Care
Relative Risk Measures – OR, RR (2/2)
Head: Surface anatomy
Head: Regions I
Violation of human rights
Head: Regions II
Diagnostic Tests (1/2)
Patient Autonomy and Implementation of Informed Consent in Medical Practice
Neck: Surface anatomy
Turkish Penal Code and Wounds I
Face
Head: Clinical Anatomy
Diagnostic Tests (1/2)
Neck: I Regions
Observation of Moral Values in Clinical Decision Making
Methods of Ethical Decision Making and Case Discussions
Neck: III Fasciae Thyroid and parathyroid glands
Neck: Clinical Anatomy
Neck: II Triangles
Alcohol and Drug Dependency
Ethical Dilemmas in Medical Practice and Clinical Ethics Committees
Survival Analysis (1/2)
Forensic Psychiatry and Behavorial Sciences
Approach to Geriatric Patient in Primary Care
Thorax: Mediastinum
Thorax: Surface anatomy
Thorax
No
56.
57.
58.
59.
60.
61.
62.
63.
64.
65.
66.
67.
68.
69.
70.
71.
72.
73.
74.
75.
76.
77.
78.
79.
Title
Survival Analysis (2/2)
Evaluation of Association Among Clinical Decision Makers
Thorax: walls and Breasts
Clinical Trials and Research Ethics Committees
Abdomen:Surface Anatomy
Approach to Pain in Primary Care
Child Abuse and Parental Violence
Thorax: Clinical Anatomy
Natural Death
Patient and Physician Rights
Abdomen: Walls
Abdomen: Inguinal region
Abdomen
Abdomen: Clinical Anatomy
Asphyxia
Sampling
Forensic Identification
Craniocerebral Trauma
Pelvic regions
Significance of Virtue Ethics for Physicians
Pelvis and Perineum: Clinical Anatomy
Methodology and Biostatistics Concepts in Clinical Research Protocol
Forensic Toxicology
Turkish Penal Code and Wounds II
Course 3.4: Endocrine System and Metabolism
Chair:
Prof. Dr. Volkan Demirhan Yumuk, Internal Medicine
Phone: +902124143000/21594 Secretary:
E-mail: volkanyumuk@superonline.com
+902124143000/21629
Vice Chairs:
Prof. Dr. Dildar Konukoğlu, Biochemistry
Prof. Dr. Saadet Olcay Evliyaoğlu, Pediatrics
Members:
Prof. Dr. Ayşe Sibel Erdamar Çetin, Pathology
Prof. Dr. Nuran Darıyerli Toktamış, Physiology
Semester:
6
Credit of Course:
12
12
Lecture (hour)
Practice (hour)
Proportion (%)
Anatomy
2
2
3
Biochemistry
19
0
18
Pharmacology
13
0
12
Physiology
12
6
14
General Surgery
3
0
3
Histology
4
2
5
Internal Medicine
22
0
22
Nuclear Medicine
1
0
1
Pathology
6
4
8
Pediatrics
8
0
8
Radiology
1
0
1
Clinical Practices
0
15
5
Total
91
29
100
Course content
Course aims
Endocrine System and Metabolism course gives information and skills about the
normal structure, development and functions, system-related diseases, etiology,
symptoms, basic clinical and laboratory findings, diagnostic methods for Endocrine
System and Metabolism and drugs used for related diseases.
Teaching function, structure, development and physiopathology of Endocrine
System and Metabolism, and basic clinical and laboratory diagnostic methods,
Learning
outcomes
Teaching
methods and
strategies
By the end of Endocrine System and Metabolism course the students should be
able to:
22. Describe development and embryonic origins,
23. Describe histological structure,
24. Describe functions and mechanisms of the endocrine system,
25. List the etiology, physiopathology, symptoms and laboratory findings of the
diseases of the endocrine system and the pathological changes due to related
disases
26. Describe the imaging techniques
27. List the treatment options of endocrin system diseases,
28. Describe the effects, mechanisms of action, pharmacokinetics, side effects and
interactions of the drugs used in the treatment of diseases of the endocrine
system
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
30.
31.
32.
33.
34.
35.
36.
37.
38.
Title
Endocrine system (1/2)
Endocrine system (2/2)
General Features of Hormones (1/2)
General Features of Hormones (2/2)
Endocrine System: Pituitary
Mechanisms of Hormone Action (1/2)
Mechanisms of Hormone Action (2/2)
Pituitary and Hypothalamic Hormones
Endocrine System: Adrenal and pineal gland
Adrenal cortex hormones: Glucocorticoids
Pituitary Hormones and The Hypotahalamic Control(1/2)
Pituitary Hormones and The Hypotahalamic Control(2/2)
The Adrenal Gland: Glucocorticoids
The Adrenal Medulla and The Renin Angiotensin System
Adrenal cortex hormones: Mineralocorticoids
Endocrine System: Thyroid and parathyroid glands
Hormones of the Adrenal Medulla
Hormonal Regulation of The Bone Formation
Adrenal gland: Medullary hormones
The Thyroid Gland
Hormonal regulatıon mechanisms of hypo and hyperglycemia
Thyroid Hormones
Parathyroid Hormones
Pancreas hormones
Fuel metabolism in diabetes
Biochemistry of acute and chronic diabetic complications
The Endocrine Functions of The Pancreas
Endocrine System: DNS system, islets of Langerhans
Neurotransmitters and hormones that influence food intake
Short and long term regulation of food intake
Metabolism and factors that affect basal metabolic rate
Metabolic homeostasis: Metabolic relationship among adipose tissue, muscle and liver
Hormones of the Adipocyte
Biochemical Evaluation of Inborn Errors of Metabolism
Biochemical Evaluation of Vitamin Metabolism Disorders
Biochemical Evaluation of Trace Element Metabolism Disorders
Lipoprotein Metabolism
Surgery of the Endocrine system: Adrenal
No
39.
40.
41.
42.
43.
44.
45.
46.
47.
48.
49.
50.
51.
52.
53.
54.
55.
56.
57.
58.
59.
60.
61.
62.
63.
64.
65.
66.
67.
68.
69.
70.
71.
72.
73.
74.
75.
76.
77.
78.
79.
80.
81.
82.
83.
84.
85.
86.
87.
88.
89.
90.
91.
Title
Introduction to endocrine pharmacology
Hypothalamus and pituitary Hormones and inhibitors (1/2)
Endocrine System Development
Symptomatology of endocrinology
Hypothalamus and pituitary Hormones and inhibitors (2/2)
Growth - Puberty
Pituitary Tumors
Adolescent
Neonatal endocrinology
Puberty
Anterior pituitary disorders
Adrenal Diseases
Short Stature
Hypothalamus and posterior pituitary disorders
Hypocorticism
Thyroid Hormones and Antithyroid drugs (1/2)
Adrenal cortex Hormones and inhibitors (1/2)
Adrenal cortex Hormones and inhibitors (2/2)
Thyroid Hormones and Antithyroid drugs (2/2)
Surgery of the endocrine system: Thyroid
Hypercorticism
Endocrine hypertension
Hyperplastic Lesions of thyroid gland
Basedow Disease, thyroiditis, thyroid tumors
Nontoxic diffuse and nodular goiter-thyroid cancer
Thyrotoxicosis
Hypothyroidism and thyroidites
Drugs affecting bone and mineral homeostasis (1/2)
Surgery of the endocrine system: Parathyroid
Nucleer Medicine in Endocrine System
Calcium homeostasis and metabolic bone diseases
Drugs affecting bone and mineral homeostasis (2/2)
Parathyroid Diseases
Male reproductive system disorders
Principals of nutrition
Female reproductive system disorders
Insulin and Oral Antidiabetic Drugs (1/3)
Tip -II Diabetes Mellitus
Introduction to inherited metabolic disorders
Diabetic neuropathy
Obesity
Type 1 diabetes mellitus
Endocrine Pancrease Pathology
Acute complications of diabetes
Diabetic nephropathy
GI hormones and endocrine tumors
Lipoprotein metabolism disorders
Macrovascular complications of diabetes
Endocrine System Radiology
Drugs used in the treatment of obesity
Hypoglycemias
Course 3.5: Clinical Microbiology and Infectious Diseases
Chair:
Prof. Dr. Neşe Saltoğlu, Infectious Diseases
Phone: +902124143000/22848
E-mail: saltoglunese@gmail.com
Secretary:
+902124143000/21688
Vice Chairs:
Prof. Nevriye Gönüllü, Microbiology
Prof. Dr. Sibel Özyazgan, Pharmacology
Members:
Prof. Dr. Ayşe Eroğlu, Pediatrics
Assoc. Prof. Dr. Kağan Zengin, General Surgery
Semester:
6
Credit of Course:
10
10
Lecture (hour)
Practice (hour)
Proportion (%)
Infectious Diseases
19
0
19
Pharmacology
18
0
17
General Surgery
1
0
1
52
12
54
Nuclear Medicine
1
0
1
Pediatrics
3
0
3
Clinical Practices
0
18
5
Total
94
30
100
Course content
Course aims
Learning
outcomes
Teaching
methods and
strategies
Includes the basic informations about microorganisms, parasites, bacteria and
fungi, clinical and laboratory properties of common infectious diseases and
properties of drugs used for infectious diseases.
It is aimed to teach basic informations about microorganisms and caused
diseases, tools for diagnosis, treatment modalities for future use.
At the end of Clinical Microbiology and Infectious Diseases Course, the studens
should be able to:
Describe pathogenic microorganisms and their characteristics
Describe symptoms of infectious diseases, clinical, laboratory and,
histopathological basic findings
Describe the procedures for diagnosis of infectious diseases
Describe the differential diagnosis and management of infectious diseases
Describe the effects, mechanisms of action and pharmacokinetics of
chemotherapeutics used for infectious disease.
Lectures, clinical and laboratory practices, demonstrations.
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
30.
31.
32.
33.
34.
35.
36.
37.
38.
39.
40.
41.
42.
43.
44.
45.
46.
47.
48.
49.
50.
51.
52.
53.
54.
55.
Title
Cell structure of bacteria and medically important bacterial pathogens
Genetic exchanges in bacteria and its outcomes
Immunology of bacterial infections 1
Immunology of bacterial infections 2
Vaccination Principles
Vaccination in adults and immunosuppressive patients
Septic shock
Principles of Diagnostic Medical Microbiology 1
Principles of Diagnostic Medical Microbiology 2
Basic principles of chemotherapy
Spectra of antibiotics
Antibiotic resistance in bacteria
Anamnesis and Physical Examination in Infectious Diseases
Laboratory findings in Infectious Diseases
Clinical uses of antimicrobials
Beta lactam Antibiotics (1/3)
The streptococci 1
The streptococci 2
The staphylococci
Bacillus species
Fever
Fever pathogenesis and clinical fever features
Approach to the patients with fever and rash
Rash
Emergency in Infectious diseases
Antistaphylococcal antibiotics and drugs used against urinary system infections
Other cell wall synthesis inhibitors
Protein synthesis inhibitors: Amphenicols
Corynebacterium and Listeria species
Nocardia and actinomycetes species and other facultative anaerob gram positive rods
Antimicrobial chemoprophylaxis in clinical practice
Differential Diagnosis in Infectious Diseases
Protein synthesis inhibitors: Macrolides- Lincosamides
Protein synthesis inhibitors: Tetracyclines
Extrapulmonary tuberculosis
Mycobacterium tuberculosis 1
Mycobacterium tuberculosis 2
Protein synthesis inhibitors: Aminoglycosides
Quinolones
Mycobacterium leprae and other mycobacteria
The Neisseriae
Enteric Gram negative rods 1
Enteric Gram negative rods 2
Salmonellosis
Vibrios and other associated bacteria
Campylobacter and Helicobacter
The Brucellae
Brucellosis
Nonfermentative Gram negative bacteria
The Haemophilus species
Bordatella and Legionella species
Sulphonamides
Francisella,Pasteurella, and Eikenella
No
56.
57.
58.
59.
60.
61.
62.
63.
64.
65.
66.
67.
68.
69.
70.
71.
72.
73.
74.
75.
76.
77.
78.
79.
80.
81.
82.
83.
84.
85.
86.
87.
88.
89.
90.
91.
92.
93.
Title
Antianaerob drugs
Spirochets and other spiral microorganisms
Anaerobic gram positive rods
Anaerobic gram negative rods and cocci
Antiprotozoals (1/2)
Nosocomial Infections
Importance of Dysinfection and sterilization in Hospital infection control
Transfusion related infections
Chlamydia and Chlamydophila species
Rickettsia, Ehrlichia, Coxiella, Bartonella
Infections in special hosts
HIV, AIDS: Clinical features, laboratory diagnosis
Introduction to parasitology
Intestinal protozoa 1
Intestinal protozoa 2
Epidemiology of infections
Interpretation of epidemiological data 1
Interpretation of epidemiological data 2
Blood and Tissue protozoa 1
Antiprotozoals (2/2)
Antihelmintic drugs
Malaria
Blood and Tissue protozoa 2
Trichomanos vaginalis and other amebas
Soft tissue infections
Scintigraphic imaging of Infection and Inflammation
Introduction to Helminthology and general characteristics of helminths
Nematodes 1
Nematodes 2
Trematodes 1
Trematodes 2
Drugs against ectoparasides
Cestodes 1
Cestodes 2
The classification and general characteristics of arthropods
Arthropoda Class Insecta mosquitoes, sandflies, bedbugs, fleas and louses
Arachnida class of arthropods ticks and mites
Clinical use of antimicrobials
4th Year Clerkships







Internal Medicine (10.5 weeks)
Pediatrics (10.5 weeks)
Gynecology and Obstetrics (7 weeks)
General Surgery (7 weeks)
Anesthesiology and Reanimation (2 weeks)
Radiodiagnostics (1.5 weeks)
Urology (3.5 weeks)
Total: 42 weeks.
Internal Medicine
Head of Department: Prof. Dr. Teoman Soysal
Phone: +902124143000/22008 Secretary:
E-mail: teomansoysal@gmail.com
+902124143000/21629
Semester:
7-8
Credit of Course:
15
15
Clerkship aims and learning outcomes
Clerkship content
Course aims
Learning
outcomes
Internal Medicine Clerkship provides an overview of important aspects of internal
Medicine.
At the end of the clerkship period students should acquire proficiency in the
diagnosis and the treatment of common primary health care problems that are
related to internal medicine
Theoretical Knowledge
Students who have completed their training of Internal Medicine should be able to
discuss the differential diagnosis of basic symptoms related to internal medicine:
Fever, abdominal pain, chest pain, shortness of breath, cough, and hemoptysis,
weight loss, headache,
For the following topics; they should be able to describe the condition, make the
correct diagnosis, plan the treatment, organize follow up, able to count situations
that a referral should be made.
Osteoporosis, and metabolic bone disease, hypertension, type 2 diabetes mellitus,
hyperlipidemias, and obesity, complications and treatment of morphological and
functional changes in aging, drug use characteristics in elderly, peptic ulcer
disease, gastritis, arthritis differential diagnosis of common rheumatic diseases,
local and generalized pain, laboratory tests in rheumatology, emergencies in
nephrology, anemia, the basic principles of medical oncology, cancer
epidemiology and etiology, screening and early diagnosis of cancer
preliminary diagnosis, (if necessary) plan the emergency treatment, able to count
situations that a referral should be made, help the long term the follow up (under
supervision of secondary health care provider)
Resistant hypertension, poisoning, pulmonary thromboembolism, systemic
sarcoidosis, type 1 diabetes mellitus, hypothyroidism, thyroiditis, hyperthyroidism,
functional diseases of the digestive system, diseases of the esophagus,
gastrointestinal system bleeding, gastrointestinal polyps and diverticular disease,
complications and treatment, chronic diarrhea, gall bladder stones, extrahepatic
biliary tract diseases, metabolic liver diseases, chronic hepatitis B, chronic
hepatitis C, liver cirrhosis, alcoholic liver disease and nonalcoholic fatty liver
disease, rheumatoid arthritis, crystal arthritis, seronegative spondyloarthropathy,
Behcet's syndrome, familial Mediterranean fever (FMF), chronic renal failure ,
Interstitial kidney disease, polycystic kidney, and congenital-hereditary kidney
disease, diabetic nephropathy, cancer screening and early diagnosis, oncologic
emergencies
preliminary diagnosis, (if necessary) plan the emergency treatment, able to
organize timely referral to appropriate unit.
Sarcoidosis, systemic, pituitary disease, adrenal disease, nodular goiter and
thyroid cancer, parathyroid disease, reproductive system disorders, inflammatory
bowel disease, acute and chronic pancreatitis, mesenteric ischemia, systemic
diseases, liver, autoimmune liver disease, acute liver failure, systemic vasculitis,
systemic sclerosis, systemic lupus erythematosus, dermatomyositis polimiyozitve,
autoinflammatory diseases, glomerular diseases, acute renal failure, systemic
diseases and kidney, renal replacement therapy, pancytopenia, thrombocytopenia
and qualitative platelet disorders, bleeding diathesis, hemophilia and von
Willebrand disease, disseminated intravascular coagulation, principles of
treatment of thrombophilia and anticoagulation, paraproteinemias and multiple
myeloma, MDS and acute leukemias, chronic leukemias, Hodgkin's Disease, NonHodgkin's Lymphoma, lung cancer, breast cancer, gastrointestinal cancers, liver,
pancreas, GEP-NET and GIST, gynecological cancers, urological cancers,
paraneoplastic syndromes, palliative and supportive care of cancer, metastatic
cancer of unknown primary, molecular oncology, cytotoxic chemotherapy and
targeted therapies
Skills
- Be able to take the correct and detailed (general and problem oriented) history,
be able to keep accurate records. Be able to do a complete and accurate physical
examination.
- Be able to help during the implementation of the basic procedures that are
related to internal medicine (thoracentesis, paracentesis, intravenously, İ.M, S.C.
drug application).
Be able to make blood glucose monitoring, prepare peripheral blood smear, able
to provide oxygen for the patient with oxygen set.
Attitude
-Health team and the staff helpful and able to communicate effectively and
compatible.
-Questioning and searching for new sources of information
Teaching methods Bedside teaching, ward-rounds, seminars
and strategies
Lectures
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
History-taking and interwiew techniques
Exemination of the general condition of the patient, evaluation of patient appereance
History-taking and physical examination of the respiratory system, pulmonary function
testing
History-taking and physical examination in nephrology, urinanalysis
History-taking and physical examination in gastroenterology
History-taking and physical examination symptoms and findings of the endocrine syystem
History-taking and physical examination rheumatology
History-taking and physical examination and the findings of the hematopoietic system
Interpretation of the diagnostic tests (specifity, sensitivity, positive and negative predictive
tests)
Differential diagnosis in a patient presenting with abdominal pain
Differential diagnosis in a patient presenting with edema
Differential diagnosis in a patient presenting with dyspnea
Differential diagnosis in a patient presenting with chest pain
Differential diagnosis in a patient presenting with hemoptysis
Differential diagnosis in a patient presenting with weight loss
Resistant hypertension
Pulmonary emboli
Systemic sarcoidosis
Atypical pneumonias
Community acquired pneumonias
Preoperative assessment of surgical patients
Anterior pituitary disorders
Posterior pituitary disorders
Adrenal disorders-1
No
25.
26.
27.
28.
29.
30.
31.
32.
33.
34.
35.
36.
37.
38.
39.
40.
41.
42.
43.
44.
45.
46.
47.
48.
49.
50.
51.
52.
53.
54.
55.
56.
57.
58.
59.
60.
61.
62.
63.
64.
65.
66.
67.
68.
69.
70.
71.
72.
73.
74.
75.
76.
77.
78.
79.
80.
81.
Adrenal disorders-2
Hypothyroidism & thyroidites
Hyperthyroidism
Nodular goiter & thyroid cancer
Parathyroid diseases
Osteoporosis & metabolic bone disease
Reproductive system disorders
Management of type 1 diabetes mellitus
Management of type 2 diabetes mellitus
Acute complications of diabetes mellitus
Chronic complications of diabetes mellitus
Diabetes & pregnancy
Hyperlipidemias and their management
Obesity: Management & its complications
History taking & PE in the elderly
Morphological & functional changes of aging
Multifaceted geriatric evaluation
Laboratory evaluation in the elderly
Nutrition principles in the elderly
Geriatric syndromes-1
Geriatric syndromes-2
Infectious diseases in the elderly
Drug treatment in the elderly
Functional disorders of the digestive system
Clinical findings & diagnosis of esophageal disorders
Treatment of esophageal disorders
Peptic ulcer disease: Etiopathogenesis & clinical presentation
Gastrites
Gastrointestinal system bleeding
GI polyps and diverticulae
Inflammatory bowel disease: Complications & management
Chronic diarrhea
Gall stones
Acute & chronic pancreatites
Mesenteric ischemia
Extrahepatic bile duct disorders
Liver in systemic diseases
Metabolic liver disease
Chronic Hepatitis B
Chronic Hepatitis C
Autoimmune liver disease
Acute hepatic failure
Liver cirrhosis
Alcoholic liver disease & Non-alcoholic steatohepatitis
Differential diagnosis of arthritis
Widespread pain & local rheumatological diseases
Laboratory in Rheumatology
Rheumatoid arthritis
Systemic vasculitis-1
Systemic vasculitis-2
Seronegative spondylarthrities
Systemic sclerosis
Systemic lupus erythematosus
Behçet‟s disease
Polimyositis & Dermatomyositis
Autoinflammatory diseases
Familial Mediterrannean Fever
No
82.
83.
84.
85.
86.
87.
88.
89.
90.
91.
92.
93.
94.
95.
96.
97.
98.
99.
100.
101.
102.
103.
104.
105.
106.
107.
108.
109.
110.
111.
112.
113.
114.
115.
116.
117.
118.
119.
120.
121.
122.
123.
124.
125.
126.
127.
128.
129.
Glomerular diseases-1
Acute renal injury-1
Acute renal injury-2
Chronic renal failure -1
Interstitial diseases of the kidney
Policystic kidney & congenital kidney diseases
Systemic diseases & kidney
Diabetic nephropathy
Renal replacement therapy-1
Renal replacement therapy-2
Emergencies in nephrology-1
Differential diagnoses of anemias
Pancytopenia
Thrombocytopenias & qualitative thrombocyte disorders
Bleeding disorders
Hemophilias & von Willebrand Disease
Disseminated intravascular coagulation
Trombophilia & principles of anticoagulation
Transfusion medicine
Paraproteinemias & multiple myeloma
MDS & acute leukemias-1
Acute leukemias-2
Chronic leukemias
Hodgkin‟s disease
Non-Hodgkin lymphomas
Basic principles of medical oncology
Etiology &epidemiology of cancer
Early diagnosis & screening in cancer
Lung Cancer
Breast cancer
Gastrointestinal cancers-1
Gastrointestinal cancers-2
Liver, pancreas GEP-NET & GIST
Gynecologic cancers
Urologic cancers-1
Urologic cancers-2
Paraneoplastic syndromes
Palliative and supportive care of cancer
Cancer of unknown origin
Molecular oncology
Cytotoxic chemotherapy & targeted therapies
Emergencies in oncology
Çocuk Sağlığı ve Hastalıkları / Pediatrics
Head of Department: Prof. Dr. Salim Çalışkan
Phone: +902124143000/22036
E-mail: salimc@istanbul.edu.tr
Secretary:
+902124143000/21831
Semester:
7-8
Credit of Course:
15
15
Clerkship content
Course aims
1. Child development
2. Child alimentation
3. The problems of newborn period
4. Gastrointestinal system diseases in children
5. Kidney and urinary tract diseases in children
6. Cardiovascular diseases in children
7. Genetic diseases
8. Metabolic diseases
9. Adolescent Problems
10. Endocrine diseases
11. Neurological diseases
12. Treatments and immunization
13. Hematologic diseases and malignant diseases in children
14. The problems requiring emergency intervention for child.
The goal of this clerkship is to provide students knowledge related child
development, nutrition, preventive medicine, diagnosis and treatment of common
pediatric diseases.
To teach things on the aim of the course part to students.
Learning
outcomes
Teaching methods Lectures, case presentations, clinical practices.
and strategies
Lectures
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
Primary Care of the newborn
Neonatal Hiperbilirubinemia
High Rish Neonate
Metabolic Problem in Newborn
Upper Respiratory Infek. - I
Upper Respiratory Infek. - II
Encephalitis
Meningitis
Parotitis
Atophy Eczema
Pertussis
Respiratory Problems of Neonatal
Intrauterin Inf.
Neonatal Sepsis
Hypoxemic Newborn
Growth and Development - I
No
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
30.
31.
32.
33.
34.
35.
36.
37.
38.
39.
40.
41.
42.
43.
44.
45.
46.
47.
48.
49.
50.
51.
52.
53.
54.
55.
56.
57.
58.
59.
60.
61.
62.
63.
64.
65.
66.
67.
68.
69.
70.
71.
72
73.
Growth and Development - II
Bronciholitis – Asthma - I
Bronciholitis – Asthma - II
Pneumonia - I
Pneumonia - II
Pubertal Disorders
Vaccination - I
Vaccination - II
Complementary Nutrition
Nutrition - I
Nutrition - II
Lysosomal Dysplasia
Skeletal Diseases
Down Syndrome
Mycocarditis
Acute Hepatitis
Cholestasis
Tubercülosis - I
Tubercülosis - II
Peptic Disease
Exanthem - I
Exanthem - II
Febril Seizures and Non Epileptic P.D.
Immun Deficiency – I
Immun Deficiency - II
Breastfeeding
Parositosis
Rachitis
Growth Hormone Deficiency
Pubertal Disorders
Coma
Adrenogenital Sydrome
Hypotirodyzm
Metabolic Diseases - I
Metabolic Diseases - II
Metabolic Diseases - III
Malabsorpsion Coeliac D.– I
Articanria - Angioedema
Diabetes Mellitus
Cystic Fibrosis
Obesity
Cardiologic Diseases - I
Cardiologic Diseases - II
Muscle Disease
ASD - PDA
VSD
Congenital Cyanotic Hearth Disease
Valve Disorders
Endocarditis - Pericarditis
Epilepsy
Atophy Eczema
Abnormal Findings in neurology
Polyradicüloneuritis
Neuro – behavioral Problems in C.
Fluid Therapy - I
Fluid Therapy - II
Intoxications
No
74.
75.
76.
77.
78.
79.
80.
81.
82.
83.
84.
85.
86.
87.
88.
89.
90.
91.
92.
93.
94.
95.
96.
97.
98.
99.
100.
101.
102.
103.
104.
105.
106.
107.
108.
Iron Deficiency Anemia
Solid Tumors
Emercery in Pediatric Hematology - Oncology
Transfusion
Thrombosis - DIC
Hemophilia and Secondary bleeding disorders
Childhood Leukemias and Lymphomas
Childhood Anemias Etiology – Clinical signs and diagnosis
Thrombocyte disorders and ITP
Haemopoesis and morphology
Hemolitic Anemias
Providing Care to Adolescent - I
Providing Care to Adolescent - II
Somatic Symptoms in Adolescence
Common Problems and Heath Risk Behaviors in Adolescent
Adolescent Preventile Services
Child Rights
Vasculitis
Systemic Lupus, Scleroderma
FMF
Juvenile İdiopatic Artrit
Acute Remal Failure
Acute Poststreptococcal Glomerulonephritis
Hypertension
Chronic Renal Failure
Hemolytic Uremic Syndrome
Congenital Urinary tract Anomalies
Voiding dysfunction and Enüresis
Tubular Disorders
Urinary tract Infection
Rabdomiyolis
Hypoglisemi
Malabsorpsion Coeliac D.– I,II
Otoenflamatuary diseases and Familial meditarian fever - I
Otoenflamatuary diseases and Familial meditarian fever - II
Case Discussions
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
History Taking I
History Taking II
Newborn Screening tests
Nutrition in Chronic Disease
Approch in Upper Respiratory tract Infection
Poisoning
Respiratory Problems of the Neonate
Primary Heath Care
Upper Gastro intestinal bleeding
Chronic Diarrhea
Tetralogy of Fallot
Aort Coarctation
Chest Pain
Genetic Counselling
Psyrosocial Problems
Prenatal Diagnosis
Tuberculosis Treatment
Approach in frequent infection
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
30.
31.
32.
33.
34.
35.
36.
37.
38.
39.
40.
41.
42.
Differantial Diagnosis Inflammatory Disease
Differantial Diagnosis in Non-inflammatory D.
Hyperbilirubinemia
Prematurity
Cough, case presentations
Approach to prolonged fever
Anaphylaxis
Anemia
Salt Losing Syndrome
Short Child
Tumor
Leukemia
Thrombosis
Bleeding
Dehydration
Nephrotic Syndrome
Nephritic Syndrome
Urinary Infection
Vaccination practices
Enurezis
Guillain Barre Syndrome
Urine Analysis
Gynecology and Obstetrics
Head of Department: Prof. Dr. Velittin Yedigöz
Phone:
E-mail:
+902124143000/21409 Secretary:
ctfkaddoghst@istanbul.edu.tr
+902124143000/21532
Semester:
7-8
Credit of Course:
10
10
Clerkship content
English
Definitions: 1 Obstetrics: Pregnancy / delivery
2 Gynecology: female genital tract diseases
Content: ensuring pregnancy, during pregnancy and maternal and infant health
along with the systemic / regional disease screening, diagnosis and treatment of
the female genital tract diseases screening, diagnosis and treatment
Obstetrics and Gynecology knowledge and practical skills to ensure learning
Knowledge and skills in the field of obstetrics and gynecology to have.
Course aims
Learning
outcomes
Teaching methods Interactive lectures, bedside teaching
and strategies
Lectures
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
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17.
18.
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20.
21.
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23.
24.
25.
26.
Introduction to Obst&Gyn and its subdivisions
Historical highlights of Obst&Gyn. History of Obs&Gyn in Turkiye
Statistics and epidemiology in Obs&Gyn
Embryology and developmental defects of female reproductive tract
Anatomy of the female genital tract: Gross anatomy,microscopic anatomy
Menstruel cycle and its neuroendocrine control (Hormone biosynthesis, metabolism and
mechanism of action
The patient in Obst&Gyn.History, physical examination and methods
Physiology and development of fetus and adnexes I
Physiology and development of fetus and adnexes II
Maternal Physiology throughout pregnancy
Abortion and early pregnancy losses
Antenatal follow-up
Assessment of fetal well-being and its methods
Normal Labor and Delivery I (Mechanism and Conduct of labor)
Normal Labor Labor and Delivery II (Obstetric analgesia and and anesthesia)
Normal Labor Labor and Delivery III (Newborn resuscitation)
Drugs,physical and chemical exposures during pregnancy and lactation
Ultrasonography in Obs&Gyn
Preterm labor and premature rupture of the membranes, Intrauterine growth restriction
Dystocia, fetopelvic dysproportion, abnormal uterine action of labor
Breech,deflexion presentations and transverse lying
Operative delivery, birth trauma and treatment
Bleeding in the late pregnancy:Placenta previa and plecantal abruption
Abnormalities of placenta, Membranes and fetus- Gestational trophoblastic Disease
Hemolytic Disease of the Newborn (Rh isoimmunisation)
Multiple pregnancy
No
27.
28.
29.
30.
31.
32.
33.
34.
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48.
49.
50.
51.
52.
53.
54.
55.
56.
57.
58.
59.
60.
Diabetes and pregnancy
Hypertension and pregnancy, Preeclampsia
Postpartum bleeding and obstetric shock
Systemic diseases and pregnancy I (Other diseases due to pregnancy)
Systemic diseases and pregnancy II (Coincidentalmedical and surgical disorders)
Amenorhea
Abnormal Gynecological Bleeding
Ectopic pregnancy (Eccyesis)
Puerperium
Infections of reproductive tract and sexually transmitted diseases
Hirsutism and PCOD
Disorders of menstruation and other gynecologic endocrine disorders
Infertility I (General)
Infertility II (Infertile Couple;Male and Female)Reproductive Endocrinology and Assisted
Reproductive Techniques)
Infertility III (Reproductive Endocrinology)
Infertility IV (Diagnostic and therapeutic aspects)
Infertility V (Assisted Reproductive Techniques)
Pelvic support defects and its treatment/Gynecological urology
Benign Lesions of vulva, vagina and cervix
Benign Lesions of uterus, tubes and ovaries
Gynecological surgery
Family Planning I (General Aspects)
Family Planning II ( Contraceptive Methods)
Endoscopic Surgery
Puberty and its disorders, adolescence
Climacterium, senium, menopause and its management
Endometriosis
Gynecologic cytopathology and general aspects of cancerology (Oncology I)
Premalignant lesions of the genital tract (Oncology II)
Malignant Lesions of Vulva and Vagina (Oncology III)
Malignant Lesions of Cervix (Oncology IV)
Premalignant and Malignant Lesions of Uterine Corpus (Oncology V)
Malignant Lesions of Fallopian Tubes and Ovaries (Epithelial) (Oncology VI)
Malignant Lesions of Ovaries (Sex cord stromal and germ cell,Choriocarcinoma) (Oncology
VII)
61.
Case Discussions
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
Contraceptive Methods and Devices
Acute Abdomen and Rupture of Ovarian Cysts
Precancerous Changes in Endometrium and Treatment
Equipment used in Gynecological Examination
Fetal Diagnosis and Treatment
Stress Incontinence
Gynecological Examination Methods
Premenopausal Transition and Menopause
Differentiation of Ex tema I Genitalia and Repercussions
Obstetrical Examination
Leiomyomas
Hirsutism
Multiple Pregnancies
Growth Retardations
Management of Ovarian Tumors and Treatment
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
30.
31.
32.
33.
34.
35.
36.
37.
38.
Bleedings in Late Pregnancy: Placenta previa and Ablatio Placenta
Screening and Diagnosis in Gynecological Cancers
Abnormal Presentations
Non-menstrual Bleeding
Difficult Labor
Ectopic Pregnancy
Operative deliveries
Diagnosis and Treatment of Pelvic Inflammatory Disease: What to do?
Cervical Lesions
Vaginal Discharges
Genetics in Gynecology
Diagnosis and Treatment of Vulvar Precancerous Lesions
Genital Organ Prolapse
Normal Vaginal Delivery
Breast Examination
Uterine factors in Abortions
Dysmenorrhea and Premenstrual Tension
Hemorrahgias
Fetal Abnormalities
Preterm Labor
Premature Rupture of the Membranes
Abortions
Puerperium and manaqement
General Surgery
Head of Department: Prof. Dr. Ertuğrul Göksoy
Phone: +902124143000/21900
E-mail: goksoy@istanbul.edu.tr
Secretary:
+902124143000/21385
Semester:
7-8
Credit of Course:
10
10
English
In this program subjects of diseases included in general surgery are given
therotically and supported with clinical applications.
Course aims
During the clerkship, sufficient informations are given to students about diseases
of gastro-intestinal, hepato-pancretico-biliary and endocrine system, breast
diseases, abdominal wall hernias, organ transplantation , emergency surgery and
trauma diseases. Students, who are the practitioner doctors of future, are also
prepared to gain the ability of diagnosing and treating the ordinary patients at first
level medical centers and direct the complicated patients to the advanced centers
Learning
At the end of clerkship period, student should obtain the history of patient,
outcomes
recognize and interprete the symptoms and signs of the disease, know the
diagnostic and therapeutic methods and list the diseases in differantial diagnosis.
Student must have an ability to diagnose and treat the ordinary patient at first level
medical centers and distinguish the right patient who will be send to 2. and 3. level
medical centers.
Teaching methods Teaching methods and strategies in clerkship of general surgery includes lectures
and strategies
and case presentations given by academic members, presentations prepared by
students, clinical rounds, practical applications on hospitalized and outpatient
patients.
Clerkship content
Lectures
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
Introduction to surgery, principles, history of surgery
Evidence- based surgery
History and physical examination in surgery
Wound healing and management
Asepsis, antisepsis and disinfection
Surgical infection and usage of antibiotics
Metabolic and endocrine response to injury
Bleeding, hemostasis blood transfusion, and its complications
Shock
Fluid and electrolyte, acid-base inbalance and treatment
Surgical metabolism and nutrition
Surgical instruments and materials
Minör surgical procedures
Surgical techniques
Surgical endoscopy
Preoperative management
Postoperative complications and patient care
Principles of surgical oncology
No
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
30.
31.
32.
33.
34.
35.
36.
37.
38.
39.
40.
41.
42.
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44.
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46.
47.
48.
49.
50.
51.
52.
53.
54.
55.
56.
57.
58.
59.
60.
61.
62.
63.
64.
65.
66.
67.
68.
69.
70.
71.
72.
Organ transplantations
History taking, symptoms, physical examination, and diagnostic methods in breast diseases
Benign breast diseases ( Masses, cysts, mastalgia, nipple discharge, breast infections )
Breast carcinoma: Symptoms and diagnosis
Treatment of breast carcinoma
Goitre and thyroiditis
Hyperthyroidism
Thyroid carcinoma
Parathyroid diseases
Adrenal diseases
Acute abdominal pain
Acute abdomen
Gastrointestinal bleedings
Bowel obstructions
Gastrointestinal fıstulas
Approach to trauma patient
Abdominal injuries
Motility disorders of esophagus
Esophageal tumors
Gastroesophageal reflux and hiatal hernia
Morbid Obesity
Surgical treatment of peptic ulcer and its complications
Esophageal perforations, burns and foreign body
Gastric tumors
Small bowel tumors (Bening-malingnant)
Acute appendicitis
Peritonitis and intraabdominal abscess
Short bowel syndrome, Meckel diverticulum, radiation enterocholitis
Diseases of the mesenterium, retroperitoneum and omentum
Abdominal compartment syndrome
Inflammatory bowel diseases
Colorectal polyps, polyposis syndromes
Diverticular diseases of the colon
Colonic carcinoma
Rectal carcinoma
Diseases of the anal region
(Tumors, anal incontinence, rectal prolapsus)
Hemorrhoidal disease
Perianal abscess, fîstula and anal fissure
Pilonidal sinüs
Inguinal hernias (Inguinal-femoral)
Abdominal wall and incisional hernias
Biliary stoııes and their complications
Acute and chronic cholecystitis
Extrahepatic cholestasis
Principles of liver surgery
Liver tumors (Benign, malignant, and metastatic)
Tumors of gallbladder and biliary tract
Pancreatic tumors
Hydatid disease of liver
Liver abscesses and non-parasitic cysts
Acute pancreatitis
Chronic pancreatitis
Portal hypertension
Splenic diseases
Case Discussions
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
30.
Thyroid nodule
Goiter
Lump in the Neck
Axillary mass
Breast lump
Nipple discharge
Acute abdomen
Acute abdominal pain ( Upper quadrants)
Acute abdominal pain (Right lower quadrant)
Acute abdominal pain (Left lower quadrant)
Postoperative acute abdomen
Abdominal mass
Abdominal mass ( Upper quadrants)
Abdominal mass (Right lower quadrant)
Abdominal mass (Left lower quadrant)
Jaundice
Liver mass
Dysphagia
Haematemesis
Melaena
Rectal bleeding
Bowel obstruction
Abdominal distension
Constipation
Perianal paiıı
Perianal swelling
Bulge in the groin area
Scrotal mass-acute pain
Multitrauma patient
Abdominal trauma
Radiology
Head of Department: Prof. Dr. İsmail Mihmanlı
Phone: +902124143000/21951 Secretary:
E-mail: mihmanli@istanbul.edu.tr
+902124143000/21209
Semester:
7-8
Credit of Course:
3
3
Clerkship content
Radiology clerkship designed to familiarize students with the interpretation of
medical images, as well as to provide opportunities for observation in various
subspecialty areas of radiology.
Course aims
The goal of clerkship (Diagnostic Radiology) is to teach the fundamental principles
of interpreting radiographic studies.
The medical student will learn the value and limitations of such studies in
commonly encountered clinical problems.
The concept of what constitutes an adequate radiographic study will be examined.
An introduction to the principles of radiation protection and the public health
implications of diagnostic radiation will also be discussed.
Learning
A specialty clerkship provides further experience for students considering a career
outcomes
in radiology or other specialties.
Opportunities are provided for students to visit the clinical areas of the various
radiology subspecialties and work on the day-to-day diagnostic problems
encountered by clinicians.
Teaching methods Lectures: Students will be scheduled in various clinical reading rooms in the
and strategies
morning, where they will be expected to independently assess the radiologic
findings of two or three cases and arrive at a defendable interpretation.
Whenever possible, differential diagnosis based upon roentgenographic findings
will be discussed.
Lectures
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
Introduction to Radiology
Abdominal Radiology
GİS Radiology
Musculoskeletal Radiology
Interventional Radiology
Invasive Neuroradiological Procedures
Noninvasive Neuroradiological Procedures
Breast Radiology
Pediatric Radiology
Ultrasound – Doppler
Chest Radiology
Case Discussions
No
1.
2.
3.
4.
İmaging techniques of lung
Pneumothorax
Bronchiectasis
Biliary tract
No
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
30.
31.
32.
33.
34.
35.
36.
37.
38.
39.
40.
41.
42.
43.
44.
45.
46.
47.
48.
49.
50.
51.
52.
53.
54.
55.
56.
57.
58.
59.
60.
61.
Abdominal Plain Film and CT (normal)
İntestinal obstruction (Plain Film+CT)
Cruris and knee Plain Film (normal)
Cervical costa Plain Film
Osteosarcoma of humerus (plain film + MR)
Lumbar spondylosis (plain film)
Ankylosing spondylitis (plain film )
Cervical spondylitis (MR)
Disc protrusion (MR)
Zencer‟s diverticulum (Barium graphy)
Achalasia (barium graphy)
Benign gastric ulcer (barium graphy)
Crohn‟s disease (barium graphy)
Colon ca (barium graphy)
Diverticulosis coli
Liver
Hepatocellular ca (CT)
Splenic subcapsular hematoma
Liver hemangioma (CT)
Renal cyst and tm (CT)
Renal cell ca 3D CT
Gallbladder stone (Plain film + US)
I.V.P. (normal)
Renal angiography (normal)
Abdominal DSA
Epidural,acute subdural,subdural hematoma CT
Subarachnoid, parenchymal hemorrhage
Brain artefacts (CT)
MCA İnfarkt (CT)
Breast invaziv ductal ca (mammography)
Breast tm ,cyst (US-MR)
Ankylosing spondylitis
Osteosarcoma
Perthes' disease
Hyperparathyroidism
Congenital developmental dysplasia of the Hip
İmaging techniques of lung
Pneumothorax
Bronchiectasis
Biliary tract
Abdominal Plain Film and CT (normal)
İntestinal obstruction (Plain Film+CT)
Cruris and knee Plain Film (normal)
Cervical costa Plain Film
Osteosarcoma of humerus (plain film + MR)
Lumbar spondylosis (plain film)
Ankylosing spondylitis (plain film)
Cervical spondylitis(MR)
Disc protrusion(MR)
Zencer‟s diverticulum (Barium graphy)
Achalasia (barium graphy)
Benign gastric ulcer (barium graphy)
Crohn‟s disease (barium graphy)
Colon ca (barium graphy)
Diverticulosis coli
Liver
Hepatocellular ca (CT)
No
62.
63.
64.
65.
66.
67.
68.
69.
70.
71.
72.
73.
74.
75.
76.
77.
78.
79.
80.
81.
82.
83.
84.
85.
86.
87.
88.
89.
90.
91.
92.
93.
94.
95.
96.
97.
98.
99.
100.
101.
102.
103.
104.
105.
106.
107.
108.
109.
110.
111.
112.
113.
114.
115.
116.
117.
118.
Splenic subcapsular hematoma
Liver hemangioma (CT)
Renal cyst and tm (CT)
Renal cell ca 3D CT
Gallbladder stone (Plain film + US)
I.V.P. (normal)
Renal angiography (normal)
Abdominal DSA
Epidural,acute subdural,subdural hematoma CT
Subarachnoid, parenchymal hemorrhage
Brain artefacts (CT)
MCA İnfarkt (CT)
Breast invaziv ductal ca (mammography)
Breast tm ,cyst (US-MR)
Ankylosing spondylitis
Osteosarcoma
Perthes' disease
Hyperparathyroidism
Congenital developmental dysplasia of the Hip
Hamartoma
Fibroadenoma
Secretuar disease
Benign cysts of breast
İnvaziv ductal carcinoma
Radial scar
Insitu ductal carcinoma
Metastatic axillary lymph nodes
Postoperative scar
Multicentric breast carcinoma
Metastatic cancer with unknown primary
Liver cyst hydatid
Liver hemangioma
Hepatocellular ca
Focal nodular hyperplasia
Renal Stone
Liver hematoma
Renal hematoma
Liver hemangioma
Appendicitis
İnvagination
Pyloric stenosis
Urinary tract infection
Testicular torsion
Epididymo-orchitis
Hepatoblastoma
Portal vein thrombosis
Lymphoma
Neuroblastoma
Lung infection
Liver laceration
Lung contusion
Renal laceration
Foreign body in bronchus
Corrosive esophageal strictures
Constipation
Duodenal stenosis
Crohn‟s disease
No
119.
120.
121.
122.
123.
124.
125.
126.
127.
128.
129.
130.
131.
132.
133.
134.
135.
136.
137.
138.
139.
140.
141.
142.
143.
144.
145.
146.
147.
148.
149.
150.
151.
152.
153.
154.
155.
156.
157.
158.
159.
160.
161.
162.
163.
164.
165.
166.
167.
168.
169.
170.
171.
172.
Hirschsprung
Vesicoureteral reflux (VUR)
Subclavian stenosis; PTA
Fibromuscular Dysplasia (FMD), right renal artery stenosis PTA
Thorocoabdominal aortic stenosis in a 9-month-old infant
Carotid stent
Left renal artery stent
Bilateral renal artery stent
Right common iliac artery occlusion , stent (contralateral approach)
Left SFA occlusion ; stent
Fibrosing mediastinitis; SVC occlusion, treatment with stent
Left external iliac artery aneurysm, cover stent
Acute transsection
İnfrarenal abdominal aortic aneurysm,treatment with endograft
Aneurysmal bone cyst of right humerus;embolization
İliac wing metastasis of malign melanoma; preoperative devascularization
Cervix ca; vaginal hemorrhage,tumoral devascularization
Right groin AVM; embolization with onyx
High-flow priapism; embolization of pudental pseudoaneurysm
Behcet disease, Hemoptysis embolization with NBCA (histoacryl)
Postpartum hemorrhage; subtotal hysterectomy
Pseudoaneurysm embolization
Right PFA post-traumatic pseudoaneurysm embolization with onyx
Post biopsy intrarenal pseudoaneurysm embolization with NBCA
HCC, Chemoembolization
Vena cava filter
Biopsies
Lytic expansile lesion in sacrum
Sclerotic lesion in distal femur, high grade osteosarcom
Lytic lesion in iliac wing; aneurysmal bone cyst
Lytic destructive soft tissue mass in thoracic vertebra
Chronic renal failure, hemodialysis patient, ossified mass in forearm, ossification related to
hyperparathyroidism,FNAB; pilomatrixoma
Necrotizing granulomatous infection TB
İliac bone post destruction and soft tissue mass ,folliculer ca metastasis
C5 destructive mass
Thyroid mass,destructive scapular mass
Lytic lesion in lumbar vertebrae
Carcinoma of the ampulla of Vater
Percutaneous transhepatic biliary drainage (external)
Percutaneous transhepatic biliary drainage (internal)
Percutan antegrad nefrostomy
RF ablation
Cement injection
Hemangioma of vertebra
Osteoporosis
Metastasis
Subarachnoid hemorrhage
Epidural hematoma
Subdural hematoma
Arteriovenous malformation
Cerebrovascular event
MRI
CT
RDUS
DSA
Congenital metabolic disease
No
173.
174.
175.
176.
177.
178.
179.
180.
181.
182.
183.
184.
185.
186.
187.
188.
189.
190.
191.
192.
193.
194.
195.
196.
197.
198.
199.
200.
201.
202.
203.
204.
205.
206.
207.
208.
209.
210.
211.
212.
213.
214.
215.
216.
217.
Hypoxic ischemic encephalopathy
Esophagus barium graphy
Anatomy of esophagus, primary and secondary wave
Esophageal diverticula ,real diverticula, pseudodiverticula
Complication of diverticula
Functional motility disorder of esophagus
Primary disorders ;Acalasia, Chalasia, Nutcracker
Esophagus, Diffuse esophageal spasm, Presbyesophagus, Tracheo-esophageal fistula
Secondary disorders; Connective tissue disorders, reflux esophagitis,caustic esophagitis,
vagotomy, radiotherapy, infectious esophageal disorders
Esophagitis;bacterial esophagitis ,viral esophagitis,fungal esophagitis,reflux esophagitis,
caustic esophagitis
GER, Grade I, Grade II ,Grade III
Reflux esophagitis
Barrett esophagus,ulcer,fibrosis,mucosal traction,intramural divertikulosis
Esophageal webb, Plummer-Vinson Syndrome
Neoplastic processes;mukosal (papilloma,polip,cancer),submucosal
(Leiomyoma,Lipoma,Hemangioma,Neurofibroma), Extrensek (ekstrensek tumoral process)
Esophagus ca (squamous,adeno ca)
Esophagus ca morfologic types(polipoid,ulcerous,annular,mixt,varicoid)
Submucosal tm
Algoritm for disfagia(esophagus barium graphy if neoplastic sign exist ; endoscopy +biopsy
Stage first choise CT ,second choise MR ,third choise for early stage tumor
endosonography)
Stent aplication (inop esophagus ca, palliative treatment of fistula)
Normal double contrast stomach graphy
Bezoar,phytobezoar,trichobezoar
Hiatal hernia (sliding,rolling, congenital hiatal hernia; morgagni , bochdalek)
Benign ulcer
Malign ulcer
Early gastric ca and classsification
Gastric tumors
a)Mucosal gastric tumors(hyperplastic polip, hamartomatous polip, adenoma,retantion
polips,adenocancer)
b) Submucosal gastric tumors(Leiomyoma, Neurofibroma, Lipoma, Hemangioma,
Leiomyosarcoma, Neurofibrosarcoma, Liposarcoma, Hemangiosarcoma, Lymphoma)
Gastric ca (ulcerovegetan type,polipoid type ulcerous type ,infiltrative type)
Primary GIS lymphoma criteria
Primary lymphoma localization
The most common localization of lymphoma is stomach
Small bowel localization is rare
Small bowel radiologic imaging (enteroclysis,small bowel barium graphy)
Normal small bowel anatomy
Meckel diverticulum
CT enteroclysis, MR enteroclysis
Malabsorption syndrome
a)İntestinal (celiac,whipple,short bowel syndrome giardiasis, amyloidosis)
b)Extraintestinal (pancreatic enzyme deficiency,gallbladder diseases, İmmerslundGrasbeck syndrome, drugs)
Radilogic findings of Celiac diseases
İntestinal diverticulosis coli
İntestinal adhesion and brids(serosal adhesion, angulasyon, tenting,brid formation,gatto
formation)
Small bowel tumors
Primary intestinal lymphoma types(polipoid,multiple nodular,circumferential segmenter
aneurysmatic,endoexoenteric with cavitation and fistula,mesenteric and mixt )
No
218.
219.
220.
221.
222.
223.
224.
225.
226.
227.
228.
229.
230.
231.
232.
233.
234.
235.
236.
237.
238.
239.
240.
241.
242.
243.
244.
245.
246.
247.
248.
249.
250.
251.
252.
253.
254.
255.
Polyposis syndromes(herediter multiple polyposis
Peutz-Jeghers syndrome, Gardner syndrome, Turcot syndrome, Crohnkide-Canada,
Juvenil polyposis, Cowden disease
Adenomas,adenocancer,carcinoid tm
Metastatic tumors of small bowel(hematogenic,direct invasion,peritoneal implantation)
inflammatory bowel disease
a) Crohn's disease(aftous ulcer,ulceronodular pattern,complications,strictures,fistula
,abscess formation)
b)Extraintestinal findings of Crohn's disease(arthritis, sacroileitis and ankylosing spondylitis,
sclerosing cholangitis, cholangiocarcinoma, cirrhosis, granulomatous hepatitis, amyloidosis,
ürolithiasis, episcleritis, pyoderma gangrenosum,thromboembolic events)
Ulcerative colitis(mucosal granularity,pseudopolip formation,polips and ca ,”lead pipe”
appearance, Backwash ileitis, toxic megacolon)
Crohn's disease (asymmetric involvement, scip area,right hemicolon,deep spicular
ulcers,fistulas, abscess formation)
Ulcerative colitis (consantric involvement, continue involvement,submucous hollow
ulcers,”lead pipe”appearance, toxic megacolon
Differential diagnosis depend on the pathologic findings
Tuberculosis
Ischemic bowel diseases
Normal colon anatomy
Congenital aganglionic megacolon
Diverticular diseases, diverticulitis
Polip (flat,spheric ,pedinculated
Benign –malign differentiation
Colon ca ( first choice CT)
Duke's classification
İmaging techniques; chest radiography,conventional tomography,
fluoroscopy,CT,HRCT,MR,USG
Chest radiography,PA graphy,lateral graphy,lateral decubitus graphy, apicolordotic
graphy,oblique graphy
Chest film;PA film,AP film,technique and positional situations
Diaphragma
Plevra ,pulmoner fissurs,pulmoner sinus
Mediastinum;right contour ,left contour
Lateral radiography(retrosternal,retrocardiac area, aortopulmoner window,vertebral
radiolucency,posterior tracheal wall,sternum,vertebrae, diaphragma,fissurs
Aortopulmoner window
Chest radiography
CT (sectional imaging)
How should optimal CT be ?
Sectional anatomy (mediastinum window, parenchym window)
Advantages of CT
HRCT
Thoracal MR(mediastinum mass ,vascular pathologies ,lung ca staging, parenchymal
assesment
Hilar expansion
Anterior mediastinum
Middle mediastinum
Posterior mediastinum
Anesthesiology and Reanimation
Head of Department: Prof. Dr. Fatiş Altındaş
Phone: +902124143000/22489
E-mail: afatis@istanbul.edu.tr
Secretary:
+902124143000/21876
Semester:
7-8
Credit of Course:
2
2
Clerkship content
Course aims
Learning
outcomes
Anaesthesia techniques, drugs used in anaesthesia practice, regional
anaesthesia, pain treatment, critical illness, foundations of critical care and
cardiopulmonary resuscitation are thought with thematic lectures and clinical
practices carried by academic staff.
Obtain information on anaesthesia and intensive care,learn to define critically ill
patient who needs urgent care, learn pain mechanisms and pain treatment, apply
advanced life support.
1. Defines anaesthesia
2. Defines general anaesthesia indications and application methods
3. Can discuss uptake and distribution of inhalational anaesthetics and defines
MAC
4. Can list four complications which can be seen during anaesthesia
5. Can list regional anaesthesia techniques
6. Can define the pharmacologic features of local anaesthetics
7. Defines physiological basis of intracranial pressure and pathophysiology of
iotracranial hypertension
8. Can define trauma and list mechanisms of trauma. Defines primary
evaluation and resuscitation of trauma victim
9. Can specify the tasks of anaesthesiologist in trauma team
10. Can list sepsis criteria completely and diagnose severe sepsis
11. Can diagnose a patient with respiratory insuffıciency
12. Can define the initial resuscitation of sepsis patient
13. Can list the criteria of acute respiratory distress syndrome (ARDS)
14. Can evaluate blood gas and acid base measurements
15. Defines the uptake and transport of oxygen, defines oxyhaemoglobin
dissociation curve, and lists the factors shift in the curve to left or right
16. Defines oxygen treatment indications and application methods
17. Can list the indications and complications of blood component transfusions
18. Can specify the fluid compartments, defines hypovolemia and hypervolemia
and lists the clinical findings of these events
19. Can diagnose electrolyte imbalances and specify the importance ofthese for
anaesthesia
20. Defines pain mechanisms
21. Can specify the principles of treatment of pain
22. Can apply advanced life support on manikin
23. Can apply emergency treatment in hypothermia, anaphylaxis and near
drowning
24. Can specify principles of clinical nutrition
25. Can list the important features of initial evaluation of unconscious patient
26. Defines the initial therapy in intoxicated patient
27. Defines the concepts of death, somatic death and brain death
28. Knows that traditional deathand brain death ara similar
29. Diagnose brain death and knows the tests for brain death
30. Knows the aethiology and pathophysiology of brain death
31. Knows the lagal framework of organ donation in the country.
Teaching methods Classes and clinical practice
and strategies
Lectures
No
1.
2.
3.
4.
5.
Introduction / information
Basic Life Support
Oxygen transport and oxygen therapy
Advanced Life Support and cardiac arrest scenarios
General anesthesia and postoperative complications
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
Fluid and electrolyte disorders and treatment
Arterial blood gases, acid base disorders
Acute respiratory failure
Anaphylaxis, near drowning and hypothermia
Transfusion of blood and blood components
Management of unconscious patient
Management of trauma patient
Local anesthetics
Regional anesthesia
Pathophysiology of pain
Assessment of pain and therapeutic approaches
Intoxications
ARDS
Sepsis
Intracranial pressure in traumatic brain injury
Basic concepts in clinical nutrition
Brain death and organ donation
Pediatric physiology and pediatric anaesthesia
Urology
Head of Department: Prof. Dr. Nur Ahmet Erözenci
Phone: +902124143000/21928
E-mail: aerozenci@yahoo.com
Secretary:
+902124143000/21011
Semester:
7-8
Credit of Course:
5
5
Clerkship content
Course aims
Learning
outcomes
Teaching methods
and strategies
Familarity about approaches to urological diseases.
To teach Symptomatology and diagnostic pathways in urological diseases.
Knowledge on when to forward the patient to a urologist Experience as a GP in
the management of urologic patients.
Seminars, case presentation, bedside teaching
Lectures
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
Introduction to urology
Patient-physician relationship
History taking
Physical examination
Urological emergencies
Urological surgical emergencies in the view of general practitioner
Cystic diseases of the kidney
Introduction to urooncology
Uroepithelial tumours
Tumors of the kidney
Bladder and renal cancers in the view of general practitioner
Anomalies of the GU system
Vesico ureteral reflux
Benign Prostate Hyperplasia
Male infertility
Infections of the GU system
Ethical considerations
Adjunct fertility methods in infertile patients, when, how?
Prostate cancer
Testicular tumors
PSA elevation
Physiology of erection
Erectile dysfunction
Peyronie disease, diagnosis and treatment
Premature ejeculation, diagnosis and treatment
Case Discussions
No
1.
2.
3.
4.
History taking
Physical examination methods
Evaluation of symptomatology
Case study: stone disease
No
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
Case study: BPH
Case study: incontinence
Case study: Scrotal diseases
Case study: andrology
Case study: instrumentation in urology
Case study: infertility
Case study: endourology
Case study: pediatric urology
Case study: uroepithelial carcinoma
Case study: prostate cancer
5th Year Clerkships
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


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Orthopedics and Traumatology (3 weeks)
Psychiatrics (2 weeks)
Neurosurgery (1 week)
Physical Medicine and Rehabilitation (3 weeks)
Neurology (3 weeks)
Ophthalmology (3 weeks)
Otorhinolaryngology (3 weeks)
Pulmonary Medicine (3 weeks)
Cardiovascular Surgery (2 weeks)
Thoracic Surgery (1 week)
Pediatric Surgery (2 weeks)
Radiation Oncology (1 week)
Plastic Surgery (2 weeks)
Nuclear Medicine (1 week)
Cardiology (3 weeks)
Infectious Diseases (3 weeks)
Forensic Medicine (2 weeks)
Public Health (2 weeks)
Dermatology (2 weeks)
Total: 42 weeks.
Orthopedics and Traumatology
Head of Department: Prof. Dr. Önder Aydıngöz
Phone: +902124143000/21398
E-mail: aydingozo@yahoo.com
Secretary:
+902124143000/21338
Semester:
9-10
Credit of Course:
4
4
Clerkship content
The 3 weeks of the Orthopaedics and Traumatology course are intended to
provide the clerk with the broad principles of orthopaedic surgery and the basics in
the individual orthopaedic surgical specialties as a foundation for pregraduate
trainingo
Course aims
This is a course that provides a wide exposure to inpatient and outpatient
orthopaedic surgery ranging from trauma and sports medicine to reconstruction.
The student integrates medical, surgical, pathological, and radiological patient
information. Patients are evaluated in both the inpatient and outpatient settings.
The student is expected to integrate book knowledge with patient care.
Learning
At the end of this clerkship, students:
outcomes
1. Describe the relevant anatomy and pathophysiology of common orthopaedic
problems including disorders involving the musculoskeletal system (muscles,
bones, joints) and neurologic system (spinal cord, and peripheral nerves).
2. Obtain an accurate, focused history from, and perform an appropriate physical
examination of, patients presenting with surgical disorders of the before
mentioned systems.
3. Request and interpret the results of appropriate laboratory and imaging
investigations for these surgical conditions, while making efficient use of limited
resources.
4. Describe the management options and appropriate strategies for treatment of
these orthopaedic conditions.
5. Participate in the initial assessment and management of a polytraumatized
patient, and Describe the priorities of resuscitation, investigation and treatment.
6. Apply clinical knowledge to recognize and prioritize Iife- and limb-threatening
illnesses and perform preliminary assessment ("sick" vs. "not sick”) of
undifferentiated emergency patients.
7. Describe and discuss the concept of triage.
Teaching methods All clerks entering clerkship will be required to attend daily mandatory teaching
and strategies
seminars (power point presentations, interactive discussions). Clerks will also be
required to attend weekly mandatory policlinic and bed side teaching seminars.
Lectures
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
Introduction to orthopaedics and traumatology
Approach to the trauma patient
Classification of fractures
Fracture healing
Open fractures
Bone and joint infections
Complications of fractures and dislocations
Osteochondroses and Legg-Calvé Perthes Disease
Developmental hip dysplasia
No
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
30.
31.
32.
33.
34.
Pediatric fractures
Fractures of spine
Deformities of the spine
Spondylolisthesis and congenital spinal disorders
Radiological examination in orthopaedics & traumatology
Physical examination of the hip
Spinal infections
Physical examination of the pediatric patients
Fractures of the proximal femur
Benign bone lesions
Malignant bone tumors
Physical examination of the knee
Injuries of the knee
Injuries around the shoulder and elbow
Physical examination of the upper extremity
Injuries of the wrist and hand
Rotator cuff tears and shoulder instabilities
Physical examination of the foot and ankle
Injuries of the foot and ankle
Foot deformities
Foot diseases
Congenital club foot
Metabolic bone diseases
Pelvis fractures and traumatic hip dislocations
Connective tissue diseases
Head of Department: Prof. Dr. Halil Koyuncu
Phone:
E-mail:
+902124143000/21945 Secretary:
ctffizikted@istanbul.edu.tr
+902124143000/21759
Semester:
9-10
Credit of Course:
4
4
Clerkship content
Contents:
Physical medicine and rehabilititaion methods, rehabilitation team definition of the
vocations of the rehabilitation team members, diseases concerning the specialty (
locomotor system as well as chronic disease processes ), physical examination,
physical therapy and rehabilitation interventions.
Course aims
To teach physical medicine and rehabilitation methods, and the comprehensive
neurologic, orthopedic and rheumatologic evaluation of a disease involving the
muskuloskeletal system.
Learning
By the end of the the clerkship students should be able to:
outcomes
1. Describe the definition of physical medicine and rehabilitation concepts,
disease, disfunction, disability and handicap
2. Take a comprehensive patient history, perform a physical examination,
diagnose disease, disfunction, disability and handicap, to manage or refere
the patient for rehabilitation.
Teaching methods Lectures, case presentations, bedside teaching, multidisciplinary meetings
and strategies
Lectures
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
Physical Medicine and Rehabilitation Definitions and Aims: Past, Present and Future
Physical Examination of the Spine
Physical Examination of the Lower Extremities
Physical Examination of the Upper Extremities
Degenerative Joint Diseases
Shoulder Pain
Rehabilitation of Spinal Cord Injury
Cervical and Lumbar Disc Herniations
Neck Pain
Spondyloarthritis
Physical Therapy Agents
Rehabilitation of Rheumatoid Arthritis
Soft Tissue Rheumatism
Pediatric Rehabilitation
Stroke Rehabilitation
Low Back Pain
Orthopedic Rehabilitation
Osteoporosis
Case Discussions
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
30.
31.
32.
33.
34.
Diagnostic Approach to the Patient with Back Pain1
Diagnostic Approach to the Patient with Back Pain2
Diagnostic Approach to the Patient with Arm Pain1
Diagnostic Approach to the Patient with Arm Pain2
Assessment of the Patient with Osteoporosis 1
Assessment of the Patient with Osteoporosis 2
Assessment of the Patient with Neck Pain 1
Assessment of the Patient with Neck Pain 2
Assessment of the Patient with Polyarthritis 1
Assessment of the Patient with Polyarthritis 2
Assessment of the Patient with Leg Pain 1
Assessment of the Patient with Leg Pain 2
Assessment of the Patient with Monoarthritis 1
Assessment of the Patient with Monoarthritis 2
Assessment of the Patient with Generalized Pain1
Assessment of the Patient with Generalized Pain 2
Assessment of the Patient with Shoulder Pain 1
Assessment of the Patient with Shoulder Pain 2
Assessment of the Patient with Neck-Arm Pain1
Assessment of the Patient with Neck-Arm Pain2
Assessment of the Patient with Knee Pain 1
Assessment of the Patient with Knee Pain 2
Assessment of the Stroke Patient 1
Assessment of the Stroke Patient 2
Assessment of the Disabled Child Patient 1
Assessment of the Disabled Child Patient 2
Assessment of the Patient with Low Back Pain 1
Assessment of the Patient with Low Back Pain 2
Assessment of the Patient with Limited Low Back Motion 1
Assessment of the Patient with Limited Low Back Motion 2
Assessment of the Paraplegic Patient 1
Assessment of the Paraplegic Patient 2
Assessment of the Acute Traumatic Patient 1
Assessment of the Acute Traumatic Patient 2
Neurology
Head of Department: Prof. Dr. Sabahattin Saip
Phone: +902124143000/22002
E-mail: psaip@superonline.com
Secretary:
+902124143000/21236
Semester:
9-10
Credit of Course:
4
4
Clerkship content
Neurologic Semiology, Neurologic Examination, Principles of Neurologic
Diagnosis.
Course aims
Practical approach to the neurologic patients, principles of neurologic diagnosis
according to the presenting symptom of the patient, neurologic examination
Learning
To make differential diagnosis of the presenting symptoms, to make complete
outcomes
neurologic examination
Teaching methods Lectures, clinical practices, case presentations
and strategies
Lectures
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
Semiology: Motor System
Semiology: Sensory System
Semiology: Mental Function
Semiolgy: Cerebellar System
Semiology: Cranial Nerves
Epilepsy: Clinic
Epilepsy: Diagnosis
Epilepsy: Treatment
Sleep and it‟s Disorders
Sleep and it‟s Disorders
Multiple Sclerosis: Clinic
Multiple Sclerosis: Diagnosis and Treatment
Pediatric Neurology: Epilepsy
Pediatric Neurology: Neurodegenerative Disorders
Pediatric Neurology: Mental Disorders
Neurological Complications of Sys.Disease
Cerebrovascular Disease: Ischemic
Cerebrovascular Disease: Hemorrhagic
Dementia
Neuropathies
Muscle Disorders
Vertigo
Neurological Complications of Sys.Disease
Primary Headache
Sekondary Headache
Movement Disorders: Parkinson‟s Disease
Movement Disorders: Dystonia and Tremor
Movement Disorders: Degenerative Disease
Movement Disorders: Treatment
Case Discussions
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
Neurological Examination
Patients with Epilepsy
Patients with Sleep Disorders
Patients with Multiple Sclerosis
Patients with Epilepsy
Patients with Vascular Disease of the Nervous System
Patients with Dementia
Patients with Neuropathy
Patients with Myopathy
Patients with Vertigo and Disequilibrium
Patients with Headache
Patients with Movement Disorders
Neurosurgery
Head of Department: Prof. Dr. Galip Zihni Sanus
Phone: +902124143000/22455
E-mail: sanus@istanbul.edu.tr
Secretary:
+902124143000/21223
Semester:
9-10
Credit of Course:
1
1
English
Neurosurgery course is carried out in five days. Lectures on main neurosurgical
topics are given and clinical practice is carried out by the academic staff. A studywork is given by the academic staff who is responsible for the student is prepared.
Course aims
The main aim of this course is to deliver the core knowledge of diseases related
with neurosurgery, which are most commonly seen during daily medical practice,
to the medical students. The learning outcomes are the minimal aim of this
course. Planning the appropiate management strategy in emergency cases
related with neurosurgey and understanding the importance, that correct decisions
in these cases are life saving is another aim. Evaluation and making the
differential diagnosis in patients with neurological symptoms is also aimed.
Learning
1. Defines Glasgow Coma Scale without any mistakes and uses in clinical
outcomes
practice
2. Defines at least 3 cardinal signs and symptoms of raised intracranial pressure
and cerebral herniation syndromes
3. Defines main concepts of head injury and performs the first evaluation, plans
the appropriate transportation of the patient
4. Defines the main concepts of spinal trauma and facilitates the transportation
accurately
5. Lists the brain tumors according to the age and location and also defines the
clinical signs, plans the radiological investigation; lists the current treatment
options
6. Defines the clinical findings and reasons of hydrocephalus in different age
groups, lists the treatment options
7. Defines major congenital neurosurgical pediatric malformations and stresses
their clinical importance
8. Can correctly diagnose the clinical findings of the subarachnoid hemorrhage
and transports appropriately to an upper level medical center
9. Can discuss the differential diagnosis of lumbar disc herniation, plans the
radiological investigations and lists the definitive surgical indications
Teaching methods Lectures (Power point presentations), video presentations, interactive discussions,
and strategies
bed-side teaching and mini-clinical evaluation, after the examination evaluation of
the course and the examination
Clerkship content
Lectures
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
Introduction to Neurosurgery and Guidelines of the Course
Functional Neuroanatomy and Clinical Neuroradiology
Cerebral Edema and Raised Intracranial Pressure
Head Injury Part I
Congenital malfomations and Craniosynostozis
Hydrocephalus
Brain Tumors Part I
Brain Tumors Part II
Cerebrovascular Diseases
Spinal Degenerative Diseases
Spinal Tumor
Spinal Trauma
Peripheral Nerve Surgery
Central Nervous System Infections
Epilepsy and Functional Surgery
Case Discussions
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
Lumbar Disc Herniation
Cervical Disc Herniation
Head Injury – Epidural Hematoma
Brain Tumor – Glial Tumor
Brain Tumor – Meningioma
Raised Intracranial Pressure
Hydrocephalus
Meningomyelocele and Tethered Cord
Spinal Tumor
Carpal Tunel Syndrome
Subarachnoid Hemorrhage
Intracerebral Hematoma
Spinal Infection
Arteriovenous Malformation
Epilepsy
Cerebello – Pontine Angle Tumor
Posterior Fossa Tumor
Spinal Trauma
Trigeminal Neuralgia
Head Injury – Subdural Hematoma
Head Injury – Multipl Trauma
Intracranial Abscess
Pituitary adenoma – Micro
Pituitary adenoma – Macro
Psychiatry
Head of Department: Prof. Dr. Alaattin Duran
Phone: +902124143000/22004
E-mail: aduran@istanbul.edu.tr
Secretary:
+902124143000/21768
Semester:
9-10
Credit of Course:
3
3
English
Basic skills on approach to the psychiatric patient are aimed to be achived
10. The genetics, neurobiology, clinical presentations, and diagnostic criteria,
treatment algorhythms about psychiatric disorders
11. In addition, knowledge about relationship between psychiatric ilnesses and
general medical conditions, interaction between psychopharmacological
drugs and drugs due to general medical conditions is aimed to be achived.
12. Skills about approaching to emergent psychiatric patients, information about
contemporay therapies are aimed to be taught
Learning
Handling a psychiatric patient from initation to the conclusion such as: diagnose,
outcomes
differential diagnose,knowing how and where to treat is aimed to be achieved.
Teaching methods Lectures and clinical practices.
and strategies
Clerkship content
Course aims
Lectures
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
Introduction to Psychiatry (Neurobiological Approach)
Introduction to Psychiatry (Dynamic Approach)
Introduction to Psychiatry (Defense mechanisms)
Psychiatric İnterview and examination
Psychiatric signs
Schizophrenia
Other Psychotic Disorders
Psyhologic Factors Effecting Medical Conditions
Somotoform Disorders
Eating and Sleeping Disorders
Anxiety Disorders
Sexual Disorders
Psychiatric Disorders Due To Alcohol
Psychiatric Disorders Due To Substance abuse
Impulse Control Disorders
Affective Disorders
Personality Disorders
Dissociative Disorders
Social Psychiatry
Factitious Disorders and Malingering
Delirium, Demantia (Geropsychiatry)
Emergency Psychiatry
Forensic Psychiatry
Treatment in Psychiatry
Psychotherapies
Child and Adolescent Psychiatry
Case Discussions
No
1.
2.
3.
4.
5.
6.
7.
Psychosis
Bipolar depression
Differential Diagnosis in Bipolar Disorder
Neurosis (Generalized Anxiety + Panic Attack + OCD )
Delirium + Dementia
Bipolar Disorder in elderly
Psychosis in elderly
Ophtalmology
Head of Department: Prof. Dr. Güzin İskeleli
Phone: +902124143000/21116
E-mail: iskeleli@istanbul.edu.tr
Secretary:
+902124143000/21117
Semester:
9-10
Credit of Course:
4
4
English
To teach the diagnosis and differential diagnosis of the major ocular diseases and
the treatment of some of them
Course aims
To teach the diagnosis and differential diagnosis of the major ocular diseases and
the treatment of some of them.
Learning
Observation of the specialist doctor in subspecialty clinics while they are working
outcomes
on the patients. Also observation of different surgeries from the video camera
system
Teaching methods Lectures, Observation of live surgery, video, case presentations, bed-side
and strategies
teaching.
Clerkship content
Lectures
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
Anatomy- Phvsiology
Refractive Errors
Methods of Examination
Strabismus
Orbital Diseases
Lachrymal Diseases
Lasers
Conjunctival Diseases
Contact Lenses
Lens Diseases
Corneal Diseases
Macular Diseases
Disorders of Retina I (Retinal Vascular Diseases)
Optic Nerver Diseases
Lid Disorders
Nystagmus
Tumors of the eye
Disorders of Retina II (Retinal Detachment)
Glaucoma I (Primary Open Angle Glaucoma)
Uveal Diseases
Glaucoma II (Congenital Glaucoma)
Red Eye
Acute Glaucoma
Case Discussions
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
Viral and bacterial conjunctivitis
Uveitis
Congenital glaucoma
Strabismus
Central and branch retinal vein occlusions
Macular edema
A case of exotropia and esotropia
Dacryocyctitis
Keratoplasty (penetrating, lamellar)
Cataracts (congenital, senil)
Keratitis
Primary open angle glaucoma
Juvenil glaucoma
Ocular hypertension
Acute glaucoma
Retinal detachment
Thyroid ophtalmopathy
Optic neuropathy
Allergic conjunctivitis
Diabetic retinopathy
Expulsive hemorrhage
Otorhinolaryngology
Head of Department: Prof. Dr. Özgün Enver
Phone: +902124143000/21871
E-mail: ozenver@istanbul.edu.tr
Secretary:
+902124143000/21520
Semester:
9-10
Credit of Course:
4
4
English
Diagnosis and treatment of diseases of ear, throat, nose, head and neck.
Contents: Diagnosis and treatment methods, definition of the vocations of the ENT
team members, diseases concerning the speciality , physical examination,
medical and surgical treatment.
Course aims
To acquire skills to examine, diagnose and treat ENT diseases
Learning
At the end of the ENT rotation the students should learn the definition of the ENT
outcomes
concepts, diseases, physical examination methods and treatments, how to take
comphrensive patient history, perform physical examination, diagnose and treat
ENT disesase
Teaching methods Lectures,case reports,bed-side teaching,multidisciplinary meetings
and strategies
Clerkship content
Lectures
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
Anatomy of the ear
Physiology of hearing
Infectious and inflammatory diseases of the ear
Otogenous complications
Diseases of the external ear
Basic Odiology
Development of hearing and language in children
Rehabilitation in hearing and language disorders
Infectious diseases of middle ear
Otogenous complications
Hearing loss
Treatment of hearing loss
Vestibuler system physiology and disorders
Anatomy and physiology of the nose and paranasal sinuses
Allergy and ENT
Infections of nose and PNS
ENT Emergencies I
ENT Emergencies II
Esthetic and reconstructive surgery in ENT
İnfectious and inflammatory diseases of the Salivary Glands
Benign and Malignant Tumors of the Salivary Glands
Facial paralysis
Sore throat and infectious-inflammatory Diseases of the oral cavity and pharynx I
Sore throat and infectious-inflammatory Diseases of the oral cavity and pharynx II
Snoring and OSAS
Anatomy of the neck and approach to neck masses
No
27.
28.
29.
30.
31.
32.
33.
34.
35.
36.
37.
Physiology and Anatomy of the Larynx
Malignanat neoplasia of the larynx
Hoarseness and inflammatory diseases of the larynx
Benign disorders of the larynx
Paralysis of the larynx
Tumors of the nasaopharynx
Deep neck space infections
Thyroid and Parathyroid Diseases-I
Thyroid and Parathyroid Diseases-II
Noplasia of the oral cavity, oropharynx and hypopharynx
Neoplasia of the Nose and PNS
Pulmonary Medicine
Head of Department: Prof. Dr. Sema Umut
Phone: +902124143000/21814
E-mail: umutsema@hotmail.com
Secretary:
+902124143000/21686
Semester:
9-10
Credit of Course:
4
4
English
3 weeks duration "Pulmonary Diseases probation" includes the theoretical lectures
and clinical practice that are accompanied by faculty members
Course aims
The aim is transferring the information about the diseases related to respiratory
system and diagnostic methods those medical students should aware for routine
practical application. The aim is to understand the importance of emergency
situations related to pulmonary diseases and to understand the importance of
common diseases of the respiratory system in the community. Tha aim is the right
differential diagnosis of diseases of the respiratory system.
Learning
1- To be aware of the important point of taking history and to be able to take
outcomes
complete medical history.
2- To apply all methods of physical examination of respiratory system
3- To evaluate chest x-ray
4- To evaluate spirometry, and knowing the indications of other respiratory
function tests (diffusing capacity, lung volumes, pulmonary pressures, reversibility,
bronchial provocation testing, exercise testing). Able to take and to interpret the
outcome of arterial blood gas.
5- To properly apply and interpret tuberculin skin test,
6-To be able to count indications, contraindications and complications of
bronchoscopy
7- To be able to put the diagnosis and giving the first treatment of asthma
attack,COPD attack, pulmonary embolism, pneumothorax, ARDS.
8-To be aware of the importance of epidemiology of tuberculosis disease; to be
able to put the diagnosis, giving right treatment and know the side effects of
treatment.
9- To be aware of the clinical and laboratory findings of lung cancer, pleural
disease, occupational lung disease, interstitial lung disease, bronchiectasis, sleeprelated breathing disorders, lung abscess and pulmonary hypertension.
10- To be aware of the importance of cigarettes for lung diseases and to be able
to discuss smoking cessation methods.
11-To be able to count the indications for oxygen therapy.
Teaching methods Giving lecture (slide presentations), interactive case presentations, practical
and strategies
application at the bedside, laboratory applications
Clerkship content
Lectures
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
30.
31.
32.
33.
The aims and objectives of Chest Diseases internship
General symptoms
Physical examination
Macro and microstructure of the lung
Chest radiology I
Chest radiology II
Lung function tests
Routine diagnostic procedures
Patogens of pulmonary tuberculosisesi
Clinic and laboratory of pulmonary tuberculosis
Pulmonary tuberculosis treatment
COPD I
COPD II
Pulmonary hypertension and cor Pulmonale
Respiratory failure and oxygen treatment
Lung cancer I
Lung canser II
İdiopathic pulmonary fibrosis
Sarcoidosis
Pulmonary emboli
Asthma I
Asthma II
Pneumonia I
Pneumonia II
Empyema-Abscess
Pulmonary Edema
Pleural diseases I
Pleural diseases II
Occupational Diseases
Smoking and lung
Bronchiectasis, and Cystic Fibrosis
Sleep related breathing disorders
Emergencies in pulmonary diseases
Cardiovascular Surgery
Head of Department: Prof. Dr. Hasan Tüzün
Phone: +902124143000/21083 Secretary:
E-mail: hasantuzun@superonline.com
+902124143000/22025
Semester:
9-10
Credit of Course:
3
3
Clerkship content
Course aims
Learning
outcomes
Teaching methods
and strategies
English
To learn surgical treatment of vascular and cardiac diseases.
To teach surgical perspectives in cardiovascular patients.
To give the correct vision diagnose and to take proper surgical treatment by a 1st
hospital doctor.
Lectures, bed-side teaching case presentations,operating room, visits and
observations
Lectures
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
Acute Arterial Occlusions
Peripheral Vascular Injuries
Introduction to Cardıovascular Surgery
Acute Arterial Aneurysms
ASD and AV Canal Defects
T.O.S and Venospatic Diseases
Coarctation of Aorta and Anomalies of The Aortic Arch
Peripheral Occlusive Arterial Diseases
Aortic Dissection
Mitral Valve Diseases
Aortic Valve Diseases
Upper Extremity and Carotid Artery Diseases
PDA
Cyanotic Cardiac Malformations Other Than Fallot
VSD
Vasculitis, Buergers and A-V Malformations
Heart and Heart-Lung Transplantation
Tetralogy of Fallot
Pericardial Diseases
Chronic Venous Diseases and Deep Vein Trombosis
Surgical Therapy Ischemic Heart Disease
Case Discussions
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
Constrictive pericarditis
Mitral valve stenosis
Aortic valve stenosis
Acute arterial embolia
Deep vein thrombosis and pulmonary embolia
Coronary arterial disease
Buerger disease
Carotid Artery Disease
Venous insufficiency
Abdominal aortic aneurysm
Tetralogy of Fallot
Chronic aorto iliac occlusions
Thoracic Surgery
Head of Department: Prof. Dr. Akif Turna
Phone: +902124143000/22486/139
E-mail: akif.turna@gmail.com
Secretary:
+902124143000/22484
Semester:
9-10
Credit of Course:
1
1
English
1. Lung Tumors and Surgical Therapy
2. Mediastinal Cysts and Tumors
3. Cystic and Suppurative Diseases of the Lung
4. Tracheal Dıseases And TOS
5. Chest Wall Deformities and Tumors
6. Pleural Diseases and Tumors
7. Thoracic Traumas and Foreign Body Aspiration
Course aims
To teach and to define;
1. What we know about lung cancer , which patients are candidate for surgery,
and steps of thoracic surgical intervention
2. Management of Mediastinal Cysts and Tumors and surgical treatment
3. Cystic and Suppurative Diseases of the Lung, to define which patients are
candidate for surgery,and steps of thoracic surgical intervention
4. What we know about tracheal Dıseases and TOS, which patients are
candidate for surgery, and steps of thoracic surgical intervention
5. Surgical treatment of Chest Wall Deformities and Tumors
6. Surgical treatment of Pleural Diseases and Tumors and patient selection
criterias
7. Emergency interventions for Thoracic Traumas and Foreign Body Aspiration,
supportive therapy and surgery
Learning
The students can define and numerate in order to acknowledge
outcomes
1. The importance and , management of lung cancer and surgical treatment
options,
2. Clinical and surgical characteristics of Mediastinal Cysts and Tumors,
management and surgical treatment options
3. Importance of Cystic and Suppurative Diseases of the Lung, management of
the patient , and surgical treatment options
4. Clinical Evaluation of Tracheal Diseases and TOS, management of Tracheal
Diseases,TOS and surgical treatment options
5. Management of Chest Wall Deformities and Tumors, patient selection criteria
6. Approach to a patient with pleural effusion and surgical treatment of pleural
tumors
7. Importance of Thoracic Traumas and Foreign Body Aspiration, emergency
interventions and supportive therapy
Teaching methods Lectures and interactive case presentations
and strategies
Clerkship content
Lectures
No
1.
2.
3.
4.
5.
6.
7.
Lung Tumors and Surgical Therapy
Mediastinal Cyst and Tumors
Cystic and Suppurative Diseases of the Lung
Tracheal Dıseases And TOS
Chest Wall Deformities and Tumors
Pleural Diseases and Tumors
Thoracic Traumas and Foreign Body Aspiration
Case Discussions
No
1.
2.
3.
4.
5.
Pleural Diseases and Thoracic Emergency
Management of Lung Mass
Management of Mediastinal Mass
Management of Chest Wall Mass
Management of Tracheal Problem
Pediatric Surgery
Head of Department: Prof. Dr. Haluk Emir
Phone: +902124143000/22260
E-mail: emir65@hotmail.com
Secretary:
+902124143000/21203
Semester:
9-10
Credit of Course:
3
3
Clerkship content
Course aims
English
24 main courses in Pediatric Surgery
To inform the students on the diagnosis and treatment of Pediatric Surgical Main
Topics
To master the theoretical and practical skills of Pediatric Surgical Problems
Learning
outcomes
Teaching methods Theoretical and practical applications, clinical rounds
and strategies
Lectures
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
Esophageal Atresia, GIS Atresia, Meconium ileus
Anorectal Malformations
Hirschsprung‟s Disease and Chronic constipation
Acute Abdomen, Appendicitis, Meckel‟s diverticulum, invaginasyon
Gastrointestinal bleeding (NEC,Polyps)
Infantile Hypertropic pyloric Stenosis and GER
Fluid electrolyte therapy
Surgical congenital Lung lesions, CDH
Abdominal Wall Defects and Thoracic deformities
Head-Neck Pathologies
Trauma, Child Abuse
Extrophy-Epispadias Complex
Penile anomalies, hypospadias, circumcission
Disorders of Sex Development
Urinary tract infections and VUR
Urinary Incontinence
Inguinal canal pathologies
Obstructive Uropathies
Urolithiasis
Pediatric age solid Tumors:(Noroblastom, Wilms, Rhabdomyosarcoma, Teratoma and
gonadal tumors)
Portal Hypertension, Surgical Jaundice, Transplantasyon
Hepatoblastoma, Congenital Malformations pf the Spleen and Pancreas
Radiation Oncology
Head of Department: Prof. Dr. İsmet Şahinler
Phone: +902124143000/22495
drismet@istanbul.edu.tr
Secretary:
+902124143000/21289
Semester:
9-10
Credit of Course:
1
1
E-mail:
Clerkship content
Course aims
Learning
outcomes
Teaching methods
and strategies
English
General concept of oncology and radiation oncology
Students must gain general concept of oncology and radiation oncology
Students must understand role of radiotherapy in the management of cancer
Classes,clinical and laboratory practices
Lectures
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11
12.
13.
The basic principles of radiation oncology
Clinical radiation oncology
Head and neck cancer
Central Nervous System Tumors
Gynecologic cancer
Pediatric tumors
Lung cancer
Urologic tumors
Breast cancer
Gastrointestinal tumors
Lymphomas
Skin tumors
Bone and soft tissue sarcomas
Case Discussions
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
Laryngeal tumors
Tumors of the prostate
Oral cavity tumors
Breast cancer
Gastrointestinal system tumors
Lung cancer
Uterus tumors
Cervix tumors
Central Nervous System Tumors
Bladder tumors
Lymphomas
Pediatric tumors
Nasopharyngeal tumor
Oropharyngeal tumors
Tumors of the ovary
Tumors of the vulva
Tumors of the testis
Plastic and Reconstructive Surgery
Head of Department: Prof. Dr. Yağmur Aydın
Phone: +902124143000/21552
E-mail: yaydin@istanbul.edu.tr
Secretary:
+902124143000/21315
Semester:
9-10
Credit of Course:
3
3
English
General plastic surgery, skin cancer, burned treatment, microsurgery topics, head
and neck cancer.
Course aims
Provide basic plastic, reconstructive and aesthetic surgery topics and techniques
Learning
At the end of Plastic Surgery internship the students should:
outcomes
1) Describe treatment methods,
2) Describe basic subjects plastic surgery.
Teaching methods Theoretical and practical expression and active participation.
and strategies
Clerkship content
Lectures
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
Wound Healing
Hypertrophic Scar and Keloid
Flaps & Grafts
Burns
Complications of Burns
Autogenous Tissue Transplantation and Use of Alloplastic Implants in Plastic Surgery
Diabetic and Chronic Wounds
Lymphedema
Hemangiomas and Vascular Malformations
Pigmented benign Lesions of Skin
Basal Cell & Squamous Cell Carcinomas of Skin
Malignant Melanoma
Intraoral Cancers
Cancers of the Perioral Region
Face Embryology, Cleft Lip & Cleft Palate
Introduction to the Craniofacial Surgery Craniofacial Microsomia and Hypertelorism
Craniosynostoses and Craniofacial Clefts
Facial Injuries
Fractures of the Lower Face
Fractures of the Mid-Face
Fractures of the Upper Face
Basic Hand Anatomy and Principles of the Hand Surgery
Congenital Anomalies of the Hand
Tendon and Nerve Injuries of the Hand
Hand Replantation
Nerve Entrapment Syndromes, Dupuytren‟s disease
Breast Reconstruction after Mastectomy
Rhinoplasty
No
29.
30.
31.
32.
33.
34.
35.
Face lifting
Blephoroplasty
Minimal invasive aesthetic procedure of the face
Breast reduction, mastopexy, breast augmentation
Abdominoplasty
Body countering and Liposuction
Postbariatric surgery
Nuclear Medicine
Head of Department: Prof. Dr. Kerim Sönmezoğlu
Phone: +902124143000/*22340
E-mail: drkerim@istanbul.edu.tr
Secretary:
+902124143000/21938
Semester:
9-10
Credit of Course:
1
1
English
The Diagnostic and therapeutic methods by using radioactive elements
To provide students the ability in diagnosis and therapy of diseases by nuclear
medicine methods
Learning
To make correct and appropriate indications for Nuclear Medicine procedures and
outcomes
to guide patients accordingly in their medical practice
Teaching methods The lectures will be given theoretically supported by experimental and clinical
and strategies
examples
Clerkship content
Course aims
Case Discussions
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
30.
Hyperthyroidism
Hypothyroidism
Thyroid Cancer
Thyroid Nodule
Thyroiditis
Patient with Ischemic Heart Disease
Viability Assessment in Myocardium
Cardiomyopathy
Myocardial Infarct
Cardiac Pet
Metastatic Bone Disease
Primary Bone Tumor
Osteomyelitis and Prosthetic Infection
Metabolic Bone Disease
Patient With Pulmonary Embolus
Gastric Emptying and Reflux
Neonatal Hepatitis and Biliary Atresia
Obstructive Disease of Biliary System
Patient with Lymphoma
Lung Cancer
Colon Cancer
Frequent Urinary System Infections
Hydronephrosis
Hydrocephalia
Dementia
Meckel Diverticula
Neuroroblastoma
Renovascular Hypertension
Neuroendocrine Tumor
Watery Eye
Cardiology
Head of Department: Prof. Dr. Hüsniye Yüksel
Phone: +902124143000/21249 Secretary:
E-mail: husniyeyuk@hotmail.com
+902124143000/21664
Semester:
9-10
Credit of Course:
4
4
Clerkship content
In cardiology clerkship, case discussions and analyses are led by the academic
staff in the morning hours and then bed-site clinical practices are carried out
under the supervisionof academicians. Lectures on main cardiology topics are
given by the academic staff in the afternoon.
Course aims
The aim of the clerkship of cardiology is to equip the students with the knowledge
and skill of implementation of the methods for prevention from cardiovascular
disease, train them to manage and diagnose the life threatening cardiac
emergencies and teach how to follow up and treat the patients with known
cardiovascular disease.
Learning
outcomes
1. Can correctly diagnose valvular disease with the means of physical examination
and laboratory examinations, knows medical management, surgical indications
and perioperative anticoagulation management.
2. To point out the significance of this subject which is a common health problem in
the community and should be acknowledged not only by cardiology specialists
but also general practitioners.
3. To emphasize the importance of symptoms and physical examination in the
diagnosis of heart failure.
4. To elucidate the necessity of support of the diagnosis with the objective findings.
5. To discuss the challenges in diagnosis and to teach the contemporary diagnostic
methods
6. To reveal the importance of evidence based medicine.
7. To teach the contemporary management.
8. To emphasize the importance of history taking and physical examination in
diagnosis of the infective endocarditis.
9. To discuss the challenges in diagnosis and criteria of diagnosis
10. To notify the importance od early diagnosis and management
11. To emphasize the importance of multidisciplinary approach in diagnosis of
infective endocarditis.
12. To discuss the frequency of common cardiac tumors in the society, to teach how
to make differential diagnosis.
The topics to learn these objectives are;
13. Epidemiology (primary and metastatic cardiac tumors)
14. Benign and malignant tumors, types, sizes and localization of tumors, clinical
characteristics, diagnostic methods and management.
15. Discuss the role of physical examination, symptoms and diagnostic methods in
the diagnosis of cardiyomyopathies.
16. Defines the classification of cardiomyopathies.
17. Elaborates on the differential diagnosis and contemporary management
methods.
18. Acquire awareness on the importance of symptoms and clinical findings in aortic
diseases.
19. Discuss the differential diagnosis and use of contemporary diagnostic tools.
20. Discuss the contemporary management of aortic diseases
21. Discuss how to prevent the complications of aortic diseases with the
implementation of contemporary management
22. Defines the types of syncope predicting sudden cardiac deaths, sudden etiology
of cardiac deaths below 30 years of age, causes of orthostatic syncope,
prevention of sudden cardiac death
23. Learns the concept of systolic pressure gradient at the level of aorta in aortic
stenosis (LV-Aorta).
24. Learns the concept diastolic pressure gradient at mitral valve in mitral stenosis
(PCWP-LVEDP).
25. Defines pulmonary capillary wedge pressure; importance and its role in definition
of pulmonary hypertension
26. Discuss contraindications and patients with high risk of death
27. Discuss contrast induced nephropathy; predisposing factors and prevention
28. Defines patients with high risk of death following the 30 days of NSTEMI
29. Defines acute management of patients with STEMI and medical management at
discharge
30. Defines advantages and disadvantages of bare metal and drug eluting stents in
patients undergoing PCI
31. Acknowledges antiplatelet management and its importance during and following
PCI
32. Classifies types of pulmonary hypertension, defines etiologic and
physiopathology factors of each type, acknowledges differential diagnosis,
management and prognosis of pulmonary hypertension. Acquires awareness of
the importance of early diagnosis.
33. Defines corpulmonale and acknowledge the diseases associated with
corpulmonale. Knows the approach in diagnosis and management of the
disease.
34. Can discuss the ECG findings of corpulmonale.
35. Acknowledges the physiologic cardiovascular changes and the associated
physical findings in normal pregnancy.
36. Can recognize the symptom and findings in cardiac diseases.
37. Defines the high risk cardiovascular states in pregnancy and knows how to guide
the patient.
38. Defines the symptoms and findings of physical of peripartum cardiomyopathy
39. Recognizes and knows the clinical significance of ventricular premature beats,
escape beat, ventricular tachycardia, ventricular fibrillation, Torsade des pointes,
idioventricular rhythm, accelerated idioventricular rhythm, ventricular asystole,
40. Defines the characteristics of stable angina pectoris and discuss the significance.
41. Defines the features of cardiac and non-cardiac chest pain and discuss the
differential diagnosis.
42. Defines the diagnostic methods used in investigation of myocardial ischemia.
43. Acknowledges the drugs prescribed in medical management of stable angina
pectoris.
44. Recognize pulmonary emboli and discuss its significance.
45. Acknowledges the etiology of pulmonary emboli.
46. Can list the diagnostic tools.
47. Can list the findings of acute right ventricular dysfunction.
48. Defines the indications of thrombolytic and anticoagulant management.
49. What are cardiovascular risk factors
50. The impact of smoking on heart
51. How to perform physical exercise?
52. How to measure body mass index and waist circumference and their normal
limits.
53. How to diagnose diabetes?
54. Correct measurement of blood pressure, normal limits and management.
55. What's dyslipidemja, what are the normal limits and how to manage
dyslipídemia?
56. What is metabolic syndrome and what are the criteria of metabolic syndrome?
57. What are the non-invasive diagnostic methods?
58. Which diagnoses are made by ECG?
59. What are the indications, contraindications and criteria for termination of the
exercise stress EGC test?
60. What is Holter examination and what are the indications for the use of Holter
monitoring?
61. Who deserves ambulatory blood pressure monitoring and what are the normal
limits?
62. What are the superiorities of echocardiography examination?
63. How and why a myocardial perfusion scintigraphy is performed?
64. Defines the pathologic cardiac findings on x-ray examination.
65. Interprets the ECG findings of supraventricular tachycardias, classifies and
manages supraventricular tachycardias in acute setting.
66. Discuss the complications and management principles of atrial fibrillation..
67. Interprets the ECG of conduction disorders and correctly diagnoses different
types of conduction abnormalities
68. Discuss the basic approach to management of patients undergoing non-cardiac
surgery.
69. Defines the concept of evidence based medicine.
70. Defines the classification of level of evidence, defines meta-analysis and
guidelines.
71. Discuss the evidence based management of cardiovascular disease.
72. Defines the symptoms and ECG findings of acute coronary syndromes,
acknowledges that the decisive management can only be done in the hospital
setting, learns what to do during the referral and transport to the hospital.
Teaching methods
The first hours of the morning, accompanied by faculty members with the ability to
and strategies
obtain recognition in cardiology applications and how to use them in discussion
and case analysis in bulk for faculty members, accompanied by a patient
applications, as described in the corporate information to the afternoon lessons.
Lectures
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
Heart valve disease l, II, III
Acute Coronary Syndrome l, II, III
Cardiac tumors
Physiopathology
Cardiomyopathies
Aortic diseases
Sybcop and sudden death
Heart catheterization and basic indications
Coronary angiography and indications
Clinical indications and contraindications of percutaneous coronary interventions
PCI in acute coronary syndromes: primary PCI in STEMI and urgent PCI in NSTEMI
ICD significance and indications
CRT mechanism and indications
Percutaneous mitral balloon valvuloplasty- indications and contraindications
Heart failure
Infective endocarditis
Clinical approach to supraventricular tachcardias
Clinical approach to conduction disorders.
Evaluation of cardiac patients undergoing non- cardiac surgery
Pulmonary hypertension and corpulmonale
Case Discussions
No
1.
2.
3.
4.
5.
Basic ECG
Pathological ECG samples
Plain chest radiogram
Cardiac symptoms
Cardiac physical examination
Infectious Diseases
Head of Department: Prof. Dr. Recep Öztürk
Phone: +902124143000/21957
E-mail: drrozturk@gmail.com
Secretary:
+902124143000/21688
Semester:
9-10
Credit of Course:
4
4
Clerkship content
Course aims
Learning
outcomes
English
Course programme includes lectures and training in order to provide general
approaches about epidemiology, diagnosis, treatment, prevention and referral
practices of the most common infectious diseases in our country and worldwide.
Trainees should gain familiarity about the etiopathogenesis, clinical and diagnostic
features, prevention measures of the most common community acquired
infections; should gain skills for diagnosis, differantial diagnosis, treatment and
follow up of outpatients; should know the basic principles the initial response of
emergent cases and referral practices.
By the end of Infectious Diseases clerkship, students should be able to:
1. Describe the most important infectious diseases for the region and the country
2. Describe the symptoms, clinical and laboratory findings of the most common
community acquired infectious diseases and the infectious and non-infectious
diseases in the differential diagnosis and apply the required medical interventions
on the primary-care level.
3. Be aware of the infections in immunocompromised hosts, infections related with
foreign devices and healthcare related infections.
4. Rationally use and interpret the diagnostic tools in community acquired
infectious diseases
5. Treat the most important community acquired infections for region and country,
recognize the complicated cases and refer to the reference centers.
6. Recognize and report the diseases those are obligatory to be reported on the
primary healhcare level.
7. Recognize emerging diseases and outbreaks in the community, get in contact
and establish relationships with relevant sides and subjects, carry out preliminary
investigations. List the principles of rational use of
8. List the principles of rational antimicrobial use , mechanisms of activity of
antimicrobial agents, spectra, side effects and drug interactions
9. Be aware of antimicrobial resistance rates and mechanisms in the most
common community acquired infections, interpret the antimicrobial susceptibility
test results.
10. Know the principles of adult immunization and chemoprophylaxis, implement
and follow up.
Teaching methods Lectures, case discussions, clinical and laboratory practices.
and strategies
Lectures
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
30.
31.
32.
33.
34.
Differential diagnosis in Infectious Diseases
Diagnosis, differential diagnosis and treatment approaches in Infectious diseases
emergencies
Differential diagnosis in acute respiratory diseases and influenza
Diagnosis, differential diagnosis and treatment in CVS Infections I
Diagnosis, differential diagnosis and treatment in CVS Infections II
Diagnosis, differential diagnosis and treatment in intraabdominal infections I
Rational laboratory use in Infectious Diseases
Antifungal and antiviral drugs
Infectious diarrhea
Bone and joint infections
HIV infection
Infections related to health services
Infections of immunocompromised hosts
Immunization in adults
Travel medicine
Important protozoal infections
Fever of unknown origin
Extrapulmonary tuberculosis
Mononucleosis syndrome (EBV, CMV)
Antibacterial drugs I
Antibacterial drugs II
Zoonotic infections I (leptospirosis, brucellosis)
Zoonotic infections II (ricketsiosis, Bartonella diseaseı, Lyme disease)
Lower respiratory tract infections
Diabetic foot infection
Urinary system infections
Skin and soft tissue infections
Treatment of intestinal paracytosis
Rational antibiotic use in clinical practice
Sepsis syndrome
Sexually transmitted diseases
Acute viral hepatitis
Chroniz viral hepatitis
New and recently importantly emerging infections
Forensic Medicine
Head of Department: Prof. Dr. Gürsel Çetin
Phone: +902124143000/21782
E-mail: gcetin@ istanbul.edu.tr
Secretary:
+902124143000/21786
Semester:
9-10
Credit of Course:
4
4
English
Turkish Penal Code and Wounds, Legal responsibilities of physicians, Violation of
human rights, Basics of death, Evaluation of forensic cases and reporting, Firearm
and explosive wounding, Wounds, Asphyxia, Forensic Psychiatry and drug
addiction, Sexual assault, Child abuse, Pregnancy and birth, Forensic Toxicology
Course aims
Acquitance of Knowledge and practice by physicians in the framework of core
content for forensic medicine.
Learning
At the end of the practice, students, besides knowdlegdes of Forensic Medicine,
outcomes
should have achieved basic knowledge of death, forensic autopsy, asphyctic
deatahs, knowledge sufficient fort he diagnosis of wounds, legal respyonsibilities
of the physician, physical hazards, sexual assaults, cihid abuse ant intra-family
violence, graviditiy, pregnanciy and abortus amd related aspects, forensic
toxicology, approach to the legal case in the level of material obtaining and further
emergency activities, issuing of legal reports, natural deaths, extenral examination
of the deceased, Traumatisation yin the framework of the Turkish Penal Code
Teaching methods Lectures and practices
and strategies
Clerkship content
Lectures
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
Introduction into Forensic Medicine
Turkish Penal Code and Wounds
Legal responsibilities of physicians
Violation of human rights
Basics of death
Filling up death form
Obtaining of a burial permit
Natural death
Evaluation of forensic cases and reporting
Firearm and explosive wounding
Wounds
Asphyxia
Forensic Psychiatry and drug addiction
Sexual assault
Child abuse
Pediatric death
Pregnancy and birth
Forensic Toxicology
Physical and chemical hazards
Forensic Identification
Medicolegal autopsy
Drowning
Medicolegal reporting
Dermatology
Head of Department: Prof. Dr. Yalçın Tüzün
Phone: +902124143000/21500
E-mail: ytuzun@istanbul.edu.tr
Secretary:
+902124143000/21546
Semester:
9-10
Credit of Course:
4
4
English
Dermatology internship gives information and skills about the etiology and
classification of leprosy, clinical symptoms and complication of the diseases.
Course aims
Teaching clinical types, clinical symptoms and clinical complications and
treatments.
Learning
At the end of dermatology clerkship the students should describe clinical types,
outcomes
clinical symptoms and clinical complications and treatments.
Teaching methods Lectures, clinical practices
and strategies
Clerkship content
Lectures
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
Dermatologic Diagnosis
Structure and Features of Skin
Differential Diagnosis of Diseses Localized Hand and Foot
Acne
Topical Therapy
Viral Skin Diseases
Psoriasis
Other Papulosquamous Diseases
Autoimmune Bullous Disorders
Syphilis
Genital Discharge
Genital HPV Infections
Genital Ulcer Diseases
Scabies, Pediculosis
Leishmaniasis Cutis
Recurrent Aphthous Stomatitis
Behçet‟s Disease
Atopic Dermatitis
Contact Dermatitis
Etiology of Skin Cancers
Malign Melanoma
Non-melanoma Skin Cancer
Precancerous Lesions
Superficial Mycoses
Streptococcal Infections
Staphylococcal Infections
Urticaria
Angioedema
Case Discussions
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
Viral skin diseases
Psoriasis and psoriasiform diseses
Autoimmune bullous disorders
Sexually transmitted diseses
Mycobacterial skin infection
Parasitic infestation of the skin
Differential diagnosis of diseses localized hand and foot
Precancerous lesions
Skin cancer
Eczematous dermatitis
Superficial mycoses
Bacterial infections
Urticaria
Public Health
Head of Department: Prof. Dr. Mehmet Sarper Erdoğan
Phone: +902124143000/22902
E-mail: sarper@istanbul.edu.tr
Secretary:
+902124143000/21566
Semester:
9-10
Credit of Course:
4
4
English
Try to teach the students with the consept of public health thinking and approach
to the problems and ensure to find solution with this consept.
Course aims
Try to teach the students with the consept of public health thinking and approach
to the problems and ensure to find solution with this consept.
Learning
Possession of information of the students on infectious diseases of global public
outcomes
struggle, the mother and child programs, chronic diseases and related public
wearing protective programs, occupational safety and worker health,
environmental health, health care organizations
Teaching methods Interactive lectures
and strategies
Clerkship content
Lectures
No
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
Control of communicable diseases: bacterial vaccines
Control of communicable diseases: viral vaccines
Control of communicable diseases: parasitic vaccines
Vaccines of gastrointestinal system
Vaccines for adults
Prevention of communicable diseases
Prevention of zoonotic diseases I
Prevention of zoonotic diseases II
Development of medical services in Turkey and basic health services
Health management
Health legislation
Health economics
Epidemiology of chronic diseases
Work injuries
Occupational health and safety
Occupational hygiene
Inequalities in health sector
Principles preventive medicine and actual problems
Organization of maternal and infant health services in Turkey
Causes of maternal death from a Public Health perspective
Causes of infant death from a Public Health perspective
Food additives and their contaminants
Nutrition of public
Methodology in medical researchs (Introduction and descriptive studies)
Methodology in medical researchs (Analytic studies)
Methodology in medical researchs (Trials)
Methodology in medical researchs (Methodological studies)
No
28.
29.
30.
31.
32.
33.
34.
35.
36.
37.
38.
39.
40.
41.
Occupational diseases caused by physical effects
Occupational diseases caused by chemical and biological effects
Informatics implementations in health sector
Health management in secondary care
Health legislation in secondary care
Effects of electromagnetism on human health
Health effects of ionized radiation and preventive measures
Evaluation of environmental effects
Climatic changes and possible effects on human health
Investigation of an outbreak with examples
Air pollution (physical, biological, chemical)
Heavy metalls and effects on health
Relation between water and health
Important environmental pollutants (Radon, PCBS, Dioxin, Furan, Radon)
6th Year Internships










Emergency Medicine (8 weeks)
Pediatrics (8 weeks)
Internal Medicine (8 weeks)
Public Medicine (6 weeks)
General Surgery (6 weeks)
Pschiatry (3 weeks)
Neurology (3 weeks)
Gynecology and Obstetrics (4 weeks),
Dermatology ( 2 weeks)
Elective ( 4 weeks)
Total: 52 weeks.

İstanbul University Cerrahpaşa Medical Faculty 2015

Transcription

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