PhytoMEga - Melaleuca

Phytomega®
Helps naturally lower cholesterol.*
Supplement Facts
Serving Size 2 Softgels
Servings Per Container 60
Amount
Per Serving
% Daily
Value
Vitamin C (as ascorbic acid)
Vitamin E (as d-alpha tocopherol)
10 mg
6 IU
Phytosterol Esters
Fish Oil Supplying 165 mg EPA
(Eicosapentaenoic Acid) and 110
mg DHA (Docosahexaenoic Acid)
Coenzyme Q10
Alpha Lipoic Acid
Proprietary Blend
1000 mg
500 mg
†
†
15 mg
15 mg
95 mg
†
†
†
Lecithin, Bromelain, Sorbitan Oleate,Triethyl Citrate
16%
20%
* Percent Daily Values are based on a 2,000 calorie diet
† Daily Value not established
Other ingredients: Gelatin, glycerin, water, lemon oil,
lycopene.
Contains fish oil concentrate from anchovy,
mackerel, and sardine.
Recommended Dosage
Take two Phytomega softgels twice daily
with food or as directed by your health
care practitioner.
Consult your physician, health care
practitioner, and/or pharmacist regarding
any health problem and before using any
supplements or before making changes in
prescribed medications. The information
presented herein is in no way intended
as a substitute for medical counseling.
Always read and follow label directions
and warnings.
The Need
Coronary heart disease is the single leading cause of death in America today. High
cholesterol levels contribute to the development of heart disease.
Supplement Facts
Competitive
Serving
Size 2 SoftgelsSolutions
Servings
Container
60 just phytosterols. Others may supply only omega-3 fatty acids.
Some Per
brands
offer
Amount
% Daily
Per Serving
Value
The Melaleuca Solution
Calories
10
Phytomega, with its research-recommended,
therapeutic daily dose of 2,000 mg of
Calories from Fat and 1,000 mg
10 of omega-3 essential fatty acids helps naturally reduce
phytosterols,
Total
Fat
1g healthy triglyceride
2%
cholesterol*
and maintain
levels†—without unwanted side effects.
Vitamin
ascorbic acid)
mg alpha lipoic
4%
Plus,Cit(asincludes
CoQ102.5and
acid to provide additional heart health benefits.*
Vitamin E (as d-alpha tocopherol) 1.5 I.U.
The Melaleuca Value
5%
Phytomega
has both phytosterols
and
750mg
Phytosterol
Esters
* omega-3 fatty acids, plus CoQ10 and alpha lipoic acid,
andOilcosts only $22.99pc
.
500mg
Fish
*
Supplying 180 mg EPA (Eicosapentaenoic Acid)
and 120 mg DHA (Docosahexaenoic Acid)
The statistics
is North America’s number one killer. In 2000,
190mgHeart disease
Proprietary
Blend are sobering:
*
62Lecithin,
million
Americans
leastCitrate
one form of cardiovascular disease. And one out of every
Bromelain,
Sorbitan had
Oleate,atTriethyl
1
2.5 deaths in 2000 was attributed to heart disease. With odds like these, chances are this
* deadly
Daily Valuedisease
not established.
will affect you—or someone you love.
Along
with
several
otherwater,
risklemon
factors, elevated LDL (or “bad”) cholesterol and abnormal
Other Ingredients: gelatin, glycerin,
oil,
carmine.
triglyceride
levels are strongly correlated as root causes of coronary heart disease.
Lifestyle changes like eating healthier foods, getting regular exercise and sleep, not
smoking, properly managing stress, and taking heart-smart supplements like Phytomega can
go a long way toward lowering your risks for heart disease.
High Blood Cholesterol: The Number One Controllable
Risk Factor for Heart Disease
According to the National Heart, Lung, and Blood Institute, the higher a person’s total
blood cholesterol level, the greater his or her risk for coronary heart disease.2 In fact, even
if blood cholesterol level is close to the desirable range, lowering it can help reduce the
risk of getting heart disease.
*Foods and supplements containing at least 400 mg per serving of plant sterol esters, eaten twice a day with meals for a daily total intake of at least
800 mg, as part of a diet low in saturated fat and cholesterol, may reduce the risk of heart disease. A daily dose of Phytomega (4 softgels) supplies at least
2,000 mg of plant sterol esters.
†Supportive but not conclusive research shows that consumption of EPA and DHA omega-3 fatty acids may reduce the risk of coronary heart disease. A
daily dose of Phytomega (4 softgels) supplies 1,000 mg of EPA and DHA.
16
The Six Major
Controllable Risk Factors
for Heart Disease
1. High blood cholesterol
2. High blood pressure
3. Smoking
4. Diabetes
5. Physical inactivity and obesity
6. Stress
In addition, three uncontrollable risk
factors are: being male, having a family
history of heart disease, and being over the
age of 45.
Cholesterol is a waxy substance found throughout your body. It helps form cell
membranes, hormones, and vitamin D. Some cholesterol is made inside your body, and
some comes from foods in your diet like meats, whole-milk dairy products, egg yolks,
poultry, and fish. Since your liver makes all the cholesterol you need, too much dietary
cholesterol and saturated fat can make blood cholesterol levels rise too high, specifically
low-density lipoprotein (LDL) cholesterol. This “bad” cholesterol can damage the inside of
the arteries that carry blood to the heart (and other parts of the body); and it can build up
in those arteries and gradually reduce or even completely block blood flow. High-density
lipoprotein (HDL) cholesterol, on the other hand, helps remove excess LDL cholesterol
from the blood—helping prevent plaque buildup. That’s why HDL is known as “good”
cholesterol.
Phytosterols: Mimicking Cholesterol to Naturally Lower
Cholesterol Levels
Each daily dose of Phytomega contains 2,000 mg of phytosterol esters. These plant-based
ingredients are found in vegetable oil, seeds, nuts, and coniferous trees. They’re essential for
stabilizing cell membranes in plants. A similar role is shared by cholesterol in animals. Since
the 1950s, phytosterols have been known to exhibit cholesterol-lowering properties by
3
inhibiting cholesterol absorption in the small intestine.
Scientists believe phytosterols work to reduce cholesterol because they have similar
4
chemical properties to cholesterol and they compete for absorption sites in the body. As
a result, phytosterols interfere with cholesterol absorption in the intestine—essentially
blocking some of the cholesterol from being absorbed by your body. The unabsorbed
cholesterol harmlessly leaves the body as waste.
Clinical Studies Show Cholesterol-Lowering Effect of Phytosterols
Scientists first discovered the effectiveness of plant sterols when they studied twelve
different aboriginal groups that still thrive today. Researchers discovered that despite
eating more fat and meat than is generally considered healthy, these primitive cultures
have healthy cardiovascular systems. The reason? These people also eat an abundance of
plant sterols!
Today, most everyone consumes plant sterols every day in their normal diet. The
amount, however, is usually not great enough to have a significant blood cholesterol
lowering effect. In order to achieve the desired cholesterol-reducing benefit, scientific
studies have shown that approximately 1 gram a day of plant sterols needs to be consumed.
Phytomega, with 2.0 grams of phytosterols, significantly boosts phytosterol intake.
In 1999, researchers conducted a study comparing four margarine spreads with
relatively low levels of plant sterols. (Margarine is used because phytosterols need to be
absorbed with a high amount of fat.) One hundred healthy volunteers consumed the
four spreads for about a month. Compared to the control spread, the three relatively
low dosages of plant sterols had a significant cholesterol-lowering effect—ranging from
4.9%–6.8% for total cholesterol, 6.7%–9.9% for LDL cholesterol, and 6.5%–7.9% for the
5
LDL/HDL cholesterol ratio.
In 2003, sixteen men
with high cholesterol levels
consumed milk containing
1.8 grams of pure plant sterols
daily and a control milk,
alternatively, during two sixday periods. Researchers found
that cholesterol absorption
cholesterol
was reduced from about 70%
phytosterols
with the control milk to 40%
with the milk containing plant
6
sterols.
17
Three More Phytosterol
Study Results
• In a 1999 trial, consumption of 2–3
grams of plant sterols reduced total
serum cholesterol by up to 6.4%.
LDL cholesterol was lowered by
12
up to 10.1%.
• In 2000, researchers investigated
the cholesterol-lowering effects of
phytosterol-enriched margarine as
part of a low-fat diet. The results? Total
cholesterol was reduced anywhere
from 7.3%–9.2% with the phytosterolenriched margarines. LDL cholesterol
13
dropped by 10.4%–12.7%.
• Also in 2000, a study showed that men
with elevated cholesterol levels who
consumed plant sterols showed a 7.9%
14
decrease in LDL cholesterol.
Omega-3 Fatty Acids Can
Benefit More Than Just
Your Heart*
Various studies show that omega-3 fatty
acids can help support:
• Healthy joints
• Nervous system function
• Eyesight
• Normal brain development
15
in children
16
• Mental health
17
• Immune system function
18
• Healthy lungs
Lower Cholesterol—
at a Much Lower Price!
(mg)
sterols
Cost
Omega(30-day
3 Fatty
Acids (mg) supply)
Phytomega
2000
1000
$22.99†
GNC
Cholesterol
Formula
800
330
$17.99‡
Punity
Products
400
Triple Action
370
$39.95‡
Solgar
Cholesterol
Formula
0
$30.20§
Products
Phyto­-
0
† Preferred Customer price. Based on daily serving.
‡Price from Drugstore.com, May 2010.
§ Price from VitaminShoppe.com, May 2010. Actual prices may vary.
Product names are trademarks or registered trademarks of their respective companies.
* These statements have not been evaluated by
the Food & Drug Administration. This product is
not intended to diagnose, treat, cure, or prevent
any disease.
Also in 2003, a trial was conducted to evaluate both the efficacy and the safety of
long-term phytosterol consumption. For a year, 185 healthy volunteers (with ages that
ranged from 34 to 64 years old) consumed 20 grams of margarine spread enriched with
1.6 grams of plant sterols and a control spread. Subjects continued their habitual diets
and lifestyles. At the end of the year, consumption of the phytosterol-enriched spread
had consistently lowered total cholesterol by 4% and LDL cholesterol by 6%. There were
7
no long-term adverse effects reported.
Phytosterols and Other Heart-Healthy Ingredients Can Effectively
Lower Cholesterol
Perhaps the most compelling study to date on phytosterols was reported in the
Journal of the American Medical Association. In 2003, researchers found that a diet rich in
8
phytosterols and fiber can reduce cholesterol levels by nearly 30%.
From the 1950s to today, the blood-cholesterol lowering effect of phytosterols has
been investigated in a large number of clinical trials on over 1,800 people, with up to
25 grams per day and durations of up to three years. No significant adverse effects have
been observed in the decades of medically supervised clinical efficacy testing and the
9
general clinical use of plant sterols.
Enhancing Phytosterol Solubility with Omega-3 Fatty Acids
Phytosterols naturally lower cholesterol levels which can make them a valuable ally
in the fight against cardiovascular disease. But phytosterol solubility in the body
traditionally proved to be a problem because phytosterols need to be taken with fat
to be effective. In the 1990s, however, it was discovered that phytosterols could be
incorporated efficiently into high-fat foods like spreads and dressings. Margarines, for
instance, are composed of 34% to 80% fat and they can carry plant sterol esters. Once
consumed, these fatty acids help release the phytosterols for use by the body.
Melaleuca’s scientists, however, chose not to use a saturated fat to form the
fatty matrix needed for Phytomega’s phytosterols. Instead, they opted for a “good”
polyunsaturated fat that has proven itself to be a natural asset to heart health—omega-3
fatty acids. Fish oil containing omega-3 fatty acids is an effective carrier for plant sterols
and it also complements a heart-healthy lifestyle which is low in saturated fat.
Omega-3 Fatty Acids: Studies Suggest Cardiovascular Benefits
Each daily dose of Phytomega contains 1,000 mg of fish oil from non-predatory fish,
which includes 330 mg of eicosapentaenoic acid (EPA) and 220 mg of docosahexaenoic
acid (DHA). These two omega-3 fatty acids received worldwide attention in the 1970s
when Danish scientists compared the coronary mortality statistics in Greenland
10
Eskimos and in Danish people living in Greenland. The scientists found few deaths
from coronary artery disease in the Eskimos—but many deaths in the Danes. After an
extensive analysis of the diet of both groups, it was discovered that the “arctic diet” of
the Eskimos—consisting of cold-water fish like whale, seal, and salmon—was high
in EPA and DHA. The Danes, however, ate a diet high in saturated fat and cholesterol
from meat and dairy products and suffered more coronary problems.
11
A 2001 study verified the results of the earlier Danish studies. Researchers
examined the diets of 426 Nunavik Inuit of Quebec aged 18 to 74. The Inuits’ blood
plasma samples were analyzed for fatty acid composition. Despite some westernization,
the Inuits still partly consume the diet of their ancestors, which is rich in fish and
marine animals. Mortality from coronary artery disease in the Inuit is 50% less than
that in the Quebec province as a whole.
In the Nurses’ Health Study, fish consumption was found to be associated with
a lower risk of coronary heart disease (CHD) and a lower rate of all-cause mortality
during 16 years of follow-up. Researchers concluded: “Findings are consistent with
the hypothesis that omega-3 fatty acids are the active agent primarily responsible for
the apparent protective effect of fish. This prospective study supports the association
18
“I have had great success with Phytomega.
I’ve been taking Phytomega for
approximately 7 weeks. In July, my total
cholesterol was 300, my HDL was 51, my
LDL was 226, and my triglycerides were
178. In October, my total cholesterol was
270, my HDL was 54, my LDL was 186,
and my triglycerides were 149. My doctor
is very pleased!” Kim Spencer, Zanesville,
Ohio
“At age 60, I am thrilled with my results
after just three months on Phytomega.
With Phytomega, my cholesterol went
from 399 to 269 and my triglycerides went
down from 254 to 181. I figured someday
someone would come up with a naturally
better solution. And Melaleuca has with
Phytomega!” Yovette Bronson, Tualatin, Oregon
“My cholesterol has always been high
and even though I exercised three days
a week, it never really made a difference
in my cholesterol level. So I took the
90-day Phytomega challenge. I took
Phytomega morning and night and I also
used FiberWise. I had my blood tested
in August and again in November. In
August my total cholesterol was 255, my
HDL was 52, my LDL was 132, and my
triglycerides were 353. In November, my
total cholesterol dropped to 147, my HDL
was 55, my LDL dropped to 78 and my
triglycerides dropped to 68! Needless to
say, I’m thrilled with Phytomega.”
Debra Kogler, Coppell, Texas
Results will vary. Always read and follow label
directions and warnings.
Supporting Research
1. The American Heart Association, 2004. National Institutes
of Health, “Facts About Blood Cholesterol.”
2. Pollak OJ, “Reduction of Blood Cholesterol in Man,”
Circulation, Vol. 7, 1953, p. 702–706.
3. SM Grundy and MA Denke, “Dietary Influences on Serum
Lipids and Lipoproteins,” Journal of Lipid Research, 1990,
Vol. 31, p. 1149–1172,
4. HFJ Hendricks, JA Westrate, T van Vliet, and GW Meijer,
“Spreads Enriched with Three Different Levels of Vegetable
Oil Sterols and the Degree of Cholesterol Lowering in
Normocholesterolemic and Mildly Hypercholesterolemic
Subjects,” European Journal of Clinical Nutrition, Vol. 53,
1999, p. 319–327.
between high fish and omega-3 fatty acid consumption and lower risk of CHD in
19
women, particularly CHD death.”
It’s important to point out that omega-3 fatty acids are classified “essential fatty
acids” because they are critical for good health—yet your body can’t produce them.
Essential fatty acids must be obtained in the diet. Supplementing your diet with
Phytomega and its 1,000 mg of fish oil significantly boosts your omega-3 fatty acid
intake!
Omega-3 Fatty Acids Help Maintain Healthy Triglyceride Levels*
Triglycerides (a type of blood fat) are an important factor for heart health. Omega3 fatty acids help maintain healthy triglyceride levels. Researchers have found that
consumption of as little as 3 grams of omega-3 fatty acids can have positive benefits.
In 2000, the American Journal of Clinical Nutrition reported that in postmenopausal
women, supplementation with 4 grams of EPA and DHA (2.4 grams EPA plus 1.6 grams
20
DHA) positively impacted triglyceride levels.
Two Large-Scale Omega-3 Supplement Studies
Many Japanese, Dutch, and U.S. studies indicate that deaths caused by coronary artery
disease are reduced by greater than 50% by the consumption of one to two fish meals a
week. However, direct clinical trials of fish oil supplements have also shown a striking
21
reduction in deaths from coronary heart disease.
One large trial called the GISSI study involved more than 11,000 men who had
22
survived a heart attack. The GISSI study examined the effects of omega-3 fatty acid
supplements or vitamin E in protecting against later cardiovascular problems. The
patients followed Mediterranean dietary habits and continued to receive appropriate
medical treatment during the study. The omega-3 group was given one gram of
combined EPA and DHA per day, and the vitamin E group was given 300 mg per
day. No effect of supplemental vitamin E was observed, but the omega-3 supplement
“significantly decreased, over 3.5 years, the rate of death, non-fatal heart attack, and
stroke.” The decrease in risk was 10% to 15%.
In a 1989 study (known as the DART study) of 2,033 men who had recovered from
heart attacks, researchers advised one group of men to eat more fish, but allowed them
to take fish oil supplements instead of fish if they preferred. Two other groups were
advised to decrease total fat consumption or to increase fiber intake. Over a two-year
period, the fish and fish oil group had a 29% reduction in risk of death from coronary
15
heart disease compared with the groups not advised to eat fish.
Researchers have just begun to scratch the surface when it comes to discovering
all the health benefits of omega-3 fatty acids. In addition to heart health, various studies
have shown omega-3s to be effective in helping with cognitive function, joint health,
mental health, digestive health, and more.*
CoQ10: The Cell’s Key to Generating Energy
CoQ10 (the more common name for coenzyme Q10) is a key component found in
every cell of the human body. It plays a major role in the cell’s ability to generate
energy. Ninety-five percent of the human body’s energy is generated this way. Those
organs with the highest energy requirements—such as the heart and the liver—
have the highest CoQ10 concentrations. CoQ10 is even more essential to those on
prescription heart health medications, as some of them have been linked with reduced
levels of CoQ10.
5. Study reported in the June 2003, Vol. 57, No. 6 issue of the
European Journal of Clinical Nutrition.
6. HFJ Hendricks, EJ Brink, GW Meijer, HMG Princen, and
FY Ntanios, “Safety of Long-Term Consumption of Plant
Sterol Esters-Enriched Spread,” European Journal of Clinical
Nutrition, Vol. 57, 2003, p. 681–692.
* These statements have not been evaluated by the Food & Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease.
19
7. DJA Jenkins, CWC Kendell, A Marchie, DA Faulkner, et
al., “Effects of a Dietary Portfolio of Cholesterol-Lowering
Foods vs Lovastatin on Serum Lipids and C-Reactive
Protein,” Journal of the American Medical Association, Vol.. 290,
2003, No. 4, p. 502–510.
8. DJ Sanders, HJ Minter, D Howes, and PA Hepburn,
“The Safety Evaluation of Phytosterol-Esters Part 6: “The
Comparative Absorption and Tissue Distribution of
Phytosterols in the Rat,” Food and Chemical Toxicology, 2000.
9. TT Nguyen, LC Dale, K von Bergmann, and IT Croghan,
“Cholesterol Lowering Effect of Stanol Ester in a US
Population of Mildly Hypercholesterolemic Men and
Women: A Randomized Controlled Trail,” Mayo Clinic
Proceedings, Vol. 74, 1999, No. 12, p. 1198–1206.
10. E Dewailly, C Blancet, S Lemieux, et al. “n-3 Fatty Acids
and Cardiovascular Disease Risk Factors Among the Inuit
of Nunavik,” American Journal of Clinical Nutrition, 2001;
74: p. 464–473.
11. FB Hu, L Bronner, WC Willett, MJ Stampfer, KM
Rexrode, CM Albert, D Hunter, JE Manson, “Fish and
Omega-3 Fatty Acid Intake and Risk of Coronary Heart
Disease in Women,” Journal of the American Medical
Association, Vol. 287, 2002, p. 1815–1821.
Alpha Lipoic Acid: A “Super” Antioxidant
Alpha lipoic acid is a fatty acid found naturally inside every cell in the body. It’s needed
by the body to produce the energy for our body’s normal functions. It is believed
that alpha lipoic acid has the ability to recycle antioxidants such as vitamin C and
glutathione after they have been used up, thus earning it the title of “super” antioxidant.
Phytomega Combines Four Natural Cardio-Protective Ingredients in
One Dietary Supplement
Scores of human clinical and animal studies have shown that a daily intake of
phytosterols and omega-3 fatty acids have beneficial effects on serum cholesterol and
LDL cholesterol levels—without causing unwanted effects. Phytomega, with 2,000
mg of phytosterols and 1,000 mg of omega-3 fatty acids, can be a safe and effective
for adults who want to naturally lower blood cholesterol levels and promote healthy
triglyceride levels. Plus, Phytomega includes CoQ10 and alpha lipoic acid for additional
heart health benefits. Phytomega, along with ProvexCV, a healthy diet, and regular
exercise, helps you make a whole-hearted effort to support your cardiovascular health.* 
12. M
A Hallikainen, ES Sarkkinen, H Gylling, and MI
Uusitupa, “Comparison of the Effects of Plant Sterol
Ester and Plant Sterol Ester-enriched Margarines
in Lowering Serum Cholesterol Concentrations in
Hypercholesterolemic Subjects Fed a Low-Fat Diet,”
European Journal of Clinical Nutrition, Vol. 54, 2000, p.
715–725.
13. PJH Jones, M Raeini-Sarjaz, FY Ntanios, CA Feng, and
W Parsons, “Modulation of Plasma Lipid Levels and
Cholesterol Kinetics by Phytosterol Versus Phytostanol
Esters,” Journal of Lipid Research, Vol. 41, 2000, p. 697–705.
14. HO Bang and J Dyerberg, “The Composition of Food
Consumed by Greenlandic Eskimos,” Acta Med Scand,
1973; 200:69–73.
15. American Journal of Clinical Nutrition, Vol.54, 1991,
p. 438–463.
16. Omega-3s improves Alzheimer’s patients quality of life,
International Journal of Neuroscience, Vol. 87, November
1996, p. 141–149.
17. Journal of Clinical Investigation, 1993, Vol. 92, p. 105–113.
18. American Journal of Clinical Nutrition, Vol. 65, April 1997,
p. 1011–1117.
19. KD Stark, EJ Park, VA Maines, BJ Holub, “Effect of Fish
Oil Concentrate on Serum Lipids in Postmenopausal
Women Receiving and Not Receiving Hormone
Replacement Therapy in a Placebo-Controlled, DoubleBlind Trial,” American Journal of Clinical Nutrition, Vol. 72,
2000, p. 389–394.
20. ML Burr, AM Fehily, JF Gilbert, et al. “Effects of Changes
in Fat, Fish, and Fibre Intakes on Death and Myocardial
Reinfarction: Diet and Reinfarction Trial (DART),” Lancet,
1989, Vol. 2, p. 757–761.
21. GISSI Prevenzione Investigators, “Dietary
Supplementation with n-3 Polyunsaturated Fatty Acids
and Vitamin E After Myocardial Infarction: Results of the
GISSI-Prevenzione Trial,” Lancet, Vol. 354, 1999,
p. 447–455.
22. ML Burr, AM Fehily, JF Gilbert, et al. “Effects of Changes
in Fat, Fish, and Fibre Intakes on Death and Myocardial
Reinfarction: Diet and Reinfarction Trail (DART), Lancet,
1989, ii: p. 757–761.
20