report to the community - Sylvester Comprehensive Cancer Center

Transcription

report to the community - Sylvester Comprehensive Cancer Center
FALL 2003
REPORT TO THE COMMUNITY
FISCAL YEAR 2003
J U N E 2 0 0 2 T H R O U GH M AY 2 0 0 3
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TABLE OF CONTENTS
1
MESSAGE FROM THE DIRECTOR
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STORIES OF HOPE
Cancer survivors reflect on how they are beating the odds.
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EVE RYD AY H ERO ES
The Sylvester family has changed the face of cancer care in
South Florida.
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ON THE FRONT LINE
Message from the Scientific Director; Scientific Programs and
Shared Resources facilitate discovery; Physicians and scientists
join UM/Sylvester.
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MILESTONES
Looking back on the cancer center’s rich history; State-of-the-art
radiation therapy and imaging services keep UM/Sylvester on the
cutting edge.
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IN THE NEWS
The Braman Family Breast Cancer Institute, UM/Sylvester at
Deerfield Beach, and a $10 million pledge from the Papanicolaou
Corps for Cancer Research topped our news stories this past year.
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MAKING A DIFFERENCE
Message from the Chairman of the Board; Support for UM/
Sylvester comes in all shapes and sizes; Special donors continue to
make a difference at the cancer center.
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FACTS AND FIGURES
Hospital and research financial profiles and clinical overview reveal
a cancer center on the move.
OUR MISSION
We seek to reduce the human burden from cancer and other serious illnesses through research,
education, prevention, and the delivery of quality patient care.
OUR VISION
UM/Sylvester will become a fully integrated program of patient care, education, and research with
an international reputation for excellence.
UM/Sylvester will provide new hope for cancer patients in our extended community, which
includes South Florida, the southeastern United States, the Caribbean, and South America.
UM/Sylvester will promote efficient, community responsive health care, and generate resources to
sustain and enhance innovative cancer programs.
OUR VALUES
Excellence • Compassion • Respect • Discovery
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MESSAGE FROM THE DIRECTOR
I
t’s been a terrific year at the University of Miami Sylvester Comprehensive Cancer Center, one marked by notable accomplishments and festive
celebrations.
UM/Sylvester celebrated its 10th anniversary during this fiscal year, while
the University of Miami School of Medicine and the Papanicolaou Corps for
Cancer Research each celebrated their 50th. Looking back on the rich history
of these organizations there is no doubt that they have left an indelible mark
on our community, one that will continue to have a positive impact for years
to come.
We take our mission to reduce the human burden from cancer very seriW. Jarrard Goodwin, M.D., F.A.C.S.
ously, and last January opened a satellite facility in Deerfield Beach. The success of UM/Sylvester at Deerfield Beach has made it increasingly evident that
the demand for our expertise in the fight against cancer extends well beyond
In January, UM/Sylvester will
county lines. Forty percent of our patients live in Broward and Palm Beach
counties, and having a significant presence there has allowed us to better serve
kick off its comprehensive
these communities. We are truly one community fighting cancer and by spreading our wings northward, our commitment has grown that much stronger.
capital campaign. We plan
UM/Sylvester has also embarked on a significant overhaul of our clinical
and research infrastructure and launched an ambitious recruitment program.
to invest $260 million to
We are looking to expand our facilities and service capabilities in several areas
to meet current and future growth. Research and clinical space renovation and
significantly grow the cancer
construction are in the advanced planning phase to allow us to pursue our
aggressive recruitment goals.
center over the next five years.
For more than two years, we have worked diligently to reorganize the way
we provide care and perform clinical research. We use a “site-based” approach
to cancer detection and treatment. This means that multidisciplinary teams of
highly trained physicians and scientists focus their attention on specific types
of cancer, based on where the cancer starts in the body. With this unique
approach, patients receive care from physicians who are not only cancer
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MESSAGE FROM THE DIRECTOR
specialists, but specialists in a particular type of cancer. With scientists particiSITE DISEASE GROUP
LEADERSHIP
pating in site disease groups, we have the opportunity to immediately transfer
research findings to the bedside, or to the patient. This is a fundamental point
O
ur priority is to better serve our patients with complex medical needs.
UM/Sylvester applies a targeted, “site-
of distinction for UM/Sylvester, which is made possible because we are a
university-based cancer center.
based” approach to treating cancer. The
In January, UM/Sylvester will kick off its comprehensive capital
13 site disease groups include:
campaign. We plan to invest $260 million to significantly grow the cancer
• Breast Cancer:
Eli Avisar, M.D.;
Joyce Slingerland, M.D., Ph.D.;
Cristiane Takita, M.D.
center over the next five years. This exciting capital campaign must raise
$137 million from friends and supporters with matching contributions from
• Colorectal Cancer:
Michael D. Hellinger, M.D.
the University of Miami and government resources. In fact, we are already
• Eye Cancer:
Arnold M. Markoe, M.D., Sc.D.;
Timothy G. Murray, M.D., F.A.C.S
closer to reaching that goal, having raised nearly $50 million during the
• Gynecologic Cancer:
Joseph A. Lucci III, M.D.;
Aaron H. Wolfson, M.D.
include an $11.5 million gift from the Sylvester family, a record-setting pledge
campaign’s “quiet phase.” Some of our most significant commitments to date
of $10 million from the Papanicolaou Corps for Cancer Research, and
• Head and Neck Cancer:
Donald T. Weed, M.D.
$5 million from the Norman and Irma Braman Family Foundation, to create
the Braman Family Breast Cancer Institute at UM/Sylvester. The dollars
• Leukemia, Lymphoma, and Myeloma:
Hugo F. Fernandez, M.D.
raised will fund the recruitment of physicians and scientists, help us expand
• Lung Cancer:
Luis E. Raez, M.D., F.A.C.P.;
Richard J. Thurer, M.D.
our clinical areas, and enhance our research programs.
• Melanoma and Related Skin Cancers:
George W. Elgart, M.D.;
Lynn G. Feun, M.D.
We also plan to compete successfully for a core research support grant
from the National Cancer Institute (NCI). All of these efforts combined—
• Neurological Cancer:
Deborah O. Heros, M.D.;
Howard J. Landy, M.D.
opening UM/Sylvester at Deerfield Beach, our clinical and research expan-
• Orthopedic Cancer:
Thomas H. Temple, M.D.
as a comprehensive cancer center by the NCI, go hand in hand in helping to
sion, recruitment efforts, the capital campaign, and the potential designation
• Pancreatic and Other Digestive Cancers:
Bach Ardalan, M.D.;
Dido Franceschi, M.D.
world-class care.
W. Jarrard Goodwin, M.D., F.A.C.S.
• Pediatric Cancer:
Stuart R. Toledano, M.D.
Director, UM/Sylvester
• Prostate, Bladder, and Kidney Cancers:
Mark S. Soloway, M.D.
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achieve our many objectives as a university-based cancer center providing
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Medical Director, UM/Sylvester at Deerfield Beach
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STORIES OF HOPE
B E AT I N G T H E O D D S
For all the new tools and scientific discoveries,
nothing more poignantly tells the tale of progress
t h a n o n e p e r s o n ’s s t o r y o f b e a t i n g t h e o d d s . A n d
a n o t h e r ’s . A n d a n o t h e r ’s . A n d a n o t h e r ’s .
W
ith each issue of Quest magazine we bring you a story of
hope. It’s a story about the incredible strength of the human
spirit and the true impact of scientific discovery.
Generally, it’s a difficult story to imagine—families going about their
business suddenly stopped in their tracks, derailed by a cancer diagnosis. But
somewhere along their journey through the disease, they
crossed paths with the physicians and scientists at UM/
Sylvester. Together they fought the battle with an impressive arsenal of tools—some from the laboratory, some from
within. And together, they are winning.
The following article is an update on the extraordinary
people we’ve profiled in Quest in the last two years. Today,
they face life with a renewed commitment to making the most of every moment and making a difference
for others who walk in their shoes.
These are the people who remind us why we are here. They are
the remarkable individuals who help
us remember that no effort is too
small in the search for a cancer cure.
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STORIES OF HOPE
M O T H E R F I N D S H O P E I N E X P E R I M E N TA L T R E AT M E N T
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hen K E R R I E B E S T (Quest, Summer 2003)
learned from Mark Goodman, M.D., an associate
professor of hematology-oncology at the University of
Miami Sylvester Comprehensive Cancer Center, that
the lower back and abdominal pains she had been experiencing on and off for more than a year were a result of
multiple myeloma, she knew she had to be strong.
But, after an initial course of oral chemotherapy
with promising results, disaster struck. Her partner of
seven years, Charles, died suddenly, leaving her to face
the disease and care for her two children alone. Best’s
condition took a turn for the worse, landing her in the
hospital, first in her home in Antigua, then in Miami.
It was a difficult time, Goodman says, further complicated by the fact
that Best’s disease failed to respond to three standard regimens of chemotherapy. So, Goodman explored the possibility of enrolling Best in a trial that
“In less than six months, the
tested the effectiveness of Arsenic Trioxide and vitamin C in destroying myeloma cells that have become resistant to standard chemotherapy.
amount of myeloma in Kerrie’s
The clinical trial, the only one of its kind in the United States, is the
brainchild of a team of UM/Sylvester scientists and physicians led by Kelvin P.
bone marrow decreased
Lee, M.D. For Best, the results were promising. “In less than six months, the
amount of myeloma in Kerrie’s bone marrow, as well as the protein that is a
notably. Her health improved
marker for the disease, decreased notably,” Lee says. And, he adds, “Her
health improved significantly.”
significantly.”
For a course of five weeks, Best received intravenous infusions daily, with
two weeks off at the end of the five-week period. That’s when she’d return to
Kelvin P. Lee, M.D.
Antigua to be with her children
before flying back to Miami to
repeat the routine. The course of
B R A I D F E E L I N G G R E AT; S E E S E V E RY D AY A S A G I F T
treatment lasted for six, sevenweek sessions.
wenty-eight months since taking a single intravenous dose of the investigaThough Best’s test results
tional drug Bexxar, K A T H Y B R A I D (Quest, Summer 2002) is feeling
still showed elevated protein
great. She isn’t showing any signs of recurrence of the low-grade lymphoma
levels after the 42-week treatment
that’s been a part of her life since 1995. It is the longest period of quiescence
period, her condition was much
she’s experienced in seven years.
improved. She has returned
“I’m doing wonderful. I just turned 51, my job is still great, and I thank
to Antigua and now comes to
God every day,” she says enthusiastically. “Every day is a gift—whether you’re
Miami once each month for
two years old or 100 years old. I realize that more and more.”
intravenous chemotherapy.
That’s the kind of positive attitude that boosted Braid last October when
She was recently approved to
her husband of almost 24 years, Kenny, suffered a mild heart attack. After a
enroll in a new trial, one she
brief hospitalization and three weeks at home, Kenny is back to work and takhopes will put an end to her
ing part in a cardiac rehabilitation program.
ordeal.
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STORIES OF HOPE
LINHART USES MEDIA TO PROMOTE CLINICAL TRIAL
A
N G E L A L I N H A R T has become a celebrity of sorts. Three years since
doctors at the University of Miami Sylvester Comprehensive Cancer
Center declared her cancer-free, the 33-year-old
“As long as you’ve got faith and
wife and mother has been telling her story. She’s
been featured in Quest (Fall 2001), the Sun-Sentinel
your health, you can get through
(December 2001) and Woman’s World (October 29,
2002). She even addressed an audience of more
everything else.”
than 600 physicians and medical professionals at a
conference promoting Bexxar, the investigational
Angela Linhart
drug that saved her life.
Linhart doesn’t have a lot of free time these
days. As the office manager at a local elementary
school and the mother of an active six-year-old girl,
Linhart is on the go. Even so, she never shies from
an opportunity to tell the story of how doctors at
UM/Sylvester used Bexxar to almost miraculously put into remission the stage
four, non-Hodgkin’s lymphoma she had been diagnosed with about a year
after the birth of her daughter, Kourtney.
“The more I can do to get the word out, the more I can help advance the
clinical trial,” she says. But that’s not all Linhart talks about when she gets the
chance. She also encourages people to appreciate life a little bit more and worry
about everything else a little bit less.
“When you’re fighting for your life, that’s big,” Linhart says. “As long as
you’ve got faith and your health, a roof over your head, and food on the table,
you can get through everything else.” She also reminds her audiences that every
person needs to take charge of his or her own health care. Had Linhart not taken
matters into her own hands after
a previous doctor gave up all hope,
she never would have found
UM/Sylvester, or the clinical trial
that turned her life around.
“We didn’t panic too much,” she says. “With evThese days, Linhart’s appointerything we’ve been through, we knew we just had to
ments at UM/Sylvester come only
deal with it and get on with our lives.”
every six months. Though her
And that’s just what she’s done. Braid has joined a gym and is enjoying
lengthy remission is very encoura new phase of life. With one son now in college, and a second in seventh
aging, Linhart doesn’t devote time
grade, Braid and her husband are finding themselves in “a whole different
to thinking about her disease. Her
ballgame,” and enjoying every minute.
thoughts are focused on more
While the cancer is important, she says it’s not the most important thing.
positive things, like the dollhouse
“It’s a part of my life; it just doesn’t rule it.”
she’s building with her daughter.
After so many rounds of chemotherapy, Braid still is amazed that a single
“I really believe in UM/Syldose of the experimental drug could produce such remarkable results. “We’re
vester,” Linhart says.“I will never
just happy and grateful,” she says. “We’re blessed.”
go anywhere else.”
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STORIES OF HOPE
SURVIVOR SHIFTS FROM RECOVERY TO ADVOCACY
T
hirty-eight-year-old M A R T Y M A S H (Quest, Spring 2002), a tongue
cancer survivor, has had a change in direction. He’s not all about recovering
these days. Instead, he’s focused on helping others deal successfully with the
unique challenges that come with head and neck cancer.
He says, quite simply, “I’m doing great,” and his doctor agrees. Truthfully,
Mash isn’t thinking about himself anymore. When he’s not busy at work as a
computer entrepreneur in the business he runs with his father, Mash is leading
UM/Sylvester’s head and neck cancer support group, offering useful tips and
friendship to survivors online, and participating in an Oxford University research study to find new cancer drugs. He’s also serving as the southeast regional
advocate for the Yul Brynner Head and Neck Cancer Foundation, and as a lay
consultant to the American College of Surgeons Oncology Group regarding
new surgical protocols for head and neck cancer. Mash is the consumer member
of the Specialty Board on Swallowing and Swallowing Disorders, which was
created by the American Speech-Language-Hearing Association.
“It’s therapy for me,” says Mash. “Part of it is a debt of gratitude, but the “From all this, I’ve learned
rest is something I need to do for myself and for others.” While his speech is not
what it once was due to the cancer, the clarity and control with which he speaks to live for today.”
are remarkable. “The way I speak,” he says, “ is a reminder to others.”
Mash admits he’s not the same person he was before the cancer. He gets
Marty Mash
tired at the end of the day and has had to make some adjustments at work. But
those adjustments, more email than phone communications, for example, seem
minor to the hurdles he already has cleared.
Today, Mash lives life differently. He no longer says, “I’ll do it tomorrow,”
and doesn’t take anything for granted. “From all this, I’ve learned to live for
today,” he says.
P AT H O F L I G H T C E L E B R A T I O N
2004 Survivors’ Day celebration scheduled for March 20 at Flamingo
Gardens in Davie, Florida. Fittingly themed, “A Celebration of Life,”
P
lease join us as we honor our loved ones who have been af-
more than 500 guests will join in the family picnic including cancer
fected by cancer. On December 8, we will remember those who
survivors, their loved ones, and UM/Sylvester cancer specialists.
have passed and celebrate those who have survived. Scheduled for
“Cancer Survivors’ Day is a truly moving and symbolic event that
7 p.m., the “Path of Light” celebration will reflect the human spirit’s
shows the world that life after a cancer diagnosis can be a reality,”
ability to cope and bring together all of us who are tied by the common
says W. Jarrard Goodwin, M.D., F.A.C.S., director, UM/Sylvester.
bond of cancer. On that day, please light a white taper—wherever
you are—and know that we are one in spirit.
UM/Sylvester’s 2004 Survivors’ Day celebration will begin at 10
a.m. at Flamingo Gardens, a 60-acre botanical garden and wildlife sanctuary in southwest Broward County. Along with a picnic-style luncheon,
S U R V I V O R S ’ D AY E V E N T P R O M I S E S
A M O V I N G C E L E B R AT I O N O F L I F E
the celebration will feature a performance by Bailey, a brain cancer
survivor who has outlived all projections as he travels the world inspiring and entertaining thousands of listeners touched by cancer.
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ationally acclaimed singer, songwriter, and cancer survivor
David M. Bailey will be the featured performer at UM/Sylvester’s
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For more information, contact Carthy Thomas, community relations manager, at 305-243-4071.
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EVE RYD AY H ERO ES
T H E S Y LV E S T E R F A M I LY:
CHANGING THE FACE OF CANCER CARE
When Harcourt Sylvester, Jr., first pledged $27.5 million to the University of Miami
in 1986, in honor of his parents, he probably never imagined the way his family’s
gift would change the face of cancer care in South Florida.
Harcourt Sylvester, Jr. and his daughters, Laura Cameron and Jayne Malfitano
“I think he dreamed the cancer center would be wonderful, but I don’t
think any of us could have imagined what it would become.”
Jayne Malfitano
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EVE RYD AY H ERO ES
I
“
think he dreamed the cancer center would be wonderful,” says daughter
Jayne Malfitano, “but I don’t think any of us could have imagined what
it would become.”
Malfitano was in her early 30s when Sylvester made the donation through
“Thanks to the extraordinary
the family foundation. The foundation was funded from the sale—to the
support of the Sylvester family,
British firm Hawker-Siddely—of the family business, Fasco, Inc., a manufacturer of a variety of fractional horsepower motors and a wide range of electri-
our cancer center is an uplifting
and special place.”
cal products for the building industry. While she and her sister, Laura
Cameron, and their now deceased brother were interested in the cause, their
father was passionate. His greatest excitement came, Malfitano says, when the
W. Jarrard Goodwin, M.D., F.A.C.S.
architects turned their attention to the building’s exterior design. The welcoming, uplifting environment that resulted from Sylvester’s keen input, including the courtyard and beautiful archway, continues to provide a
tremendous benefit for the patients, visitors, and staff of the cancer center.
The initial multimillion dollar
donation made through the Harcourt
and Virginia Sylvester Foundation of
Palm Beach was like none other in the
University of Miami’s history. But the
family’s commitment to cancer care
didn’t end there. In 1988, the family
added another $5 million to their
original pledge to help fund the construction and maintenance of what
would become the University of
Miami Sylvester Comprehensive Cancer Center.
Having seen his grandchild survive cancer, Sylvester was later moved
to do something more. He pledged an
additional $5 million to create a cancer research floor in the Batchelor Institute for Children’s Research at the
University of Miami School of
Medicine.
Recently, the Sylvester family contributed an additional $11.5 million
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to UM/Sylvester’s capital campaign,
which means that the Sylvester Foundation has contributed or pledged
more than $50 million to fund programs in the University of Miami
School of Medicine. The Sylvester
Foundation was recently inducted
into the University’s new Millennium
Society.
“Thanks to the extraordinary support of the Sylvester family, our cancer center is an uplifting and special
place,” said UM/Sylvester director, W.
Jarrard Goodwin, M.D., F.A.C.S.
Along with the Sylvester family’s
generous financial support, their input and guidance over the years have
been important factors in the continued growth and success of the cancer
center.
Today, Malfitano participates actively on the UM/Sylvester Board of
Governors and is a member of the
Marketing Committee of the Board.
Last March, Sylvester and his daughters were on stage for the ribbon cutting ceremony to mark the opening
of UM/Sylvester at Deerfield Beach,
a 10,000-square-foot satellite facility
located on the corner of I-95 and S.W.
10th Street, on the county line. It was
an important day for the family, who
all live nearby in Palm Beach County.
Jayne and Laura are honored to have
the torch passed to them and to further help the cancer center’s ability to
positively impact the South Florida
community, and indeed the entire
cancer initiative.
“My father feels a great connection with all the people he comes
in contact with at UM/Sylvester, and
that inspires him to do more,” says
Malfitano.
“He has always been so understated;
he just wants to make a difference.”
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ON THE FRONT LINE
MESSAGE FROM THE SCIENTIFIC DIRECTOR
R
esearch is curing cancer, and to further achieve that goal, the
University of Miami Sylvester Comprehensive Cancer Center
continues to build upon its excellent scientific programs already in
place. We are expanding our portfolio of clinical trials and developing new
multidisciplinary initiatives and site disease groups. What’s more, these efforts
extend across departmental lines, which will allow us to provide state-of-theart care and conduct innovative clinical research.
The five long-standing, multidisciplinary scientific programs within
UM/Sylvester afford unique training opportunities for our residents and fellows and include Tumor Cell Biology, Tumor Immunology, Viral Oncology,
Cancer Prevention and Control, and the Clinical Oncology Research Program.
Joseph D. Rosenblatt, M.D.
Research breakthroughs that will result in new types of treatment are on
the horizon. Theodore J. Lampidis, Ph.D., together with Luis E. Raez, M.D.,
F.A.C.P., is developing new approaches to lung cancer. Khaled Tolba, M.D.,
continues his research efforts in developing immune therapy approaches to
fight cancer. Izidore Lossos, M.D., focuses on lymphoma and has already
identified two genes that appear to be very important prognostic indicators in
large cell lymphoma.
UM/Sylvester is especially invested in the development of home grown
clinical trials based on science and technology developed at the University
of Miami.
We have seen a steady increase in National Cancer Institute (NCI)
funding for research at UM/Sylvester during fiscal year 2003, from $10.2 million in 2002 to $10.8 million in 2003. And, since research is at the heart of
UM/Sylvester’s mission, this increase in funding will drive advancements that
can be moved from the laboratory to the patient’s bedside (known as translational research) more quickly than ever before.
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ON THE FRONT LINE
Recruiting prominent clinical researchers to our already distinguished
faculty remains a primary focus. UM/Sylvester has already recruited
Research is curing cancer and
world-renowned breast cancer physician-scientist Joyce Slingerland, M.D.,
Ph.D., from the University of Toronto, to direct the Braman Family Breast
the University of Miami Sylvester
Cancer Institute at UM/Sylvester. Rakesh Singal, M.D., M.R.C.P., joined
UM/Sylvester this year as an associate professor of medicine in the Division
Comprehensive Cancer Center
of Hematology-Oncology, from Louisiana State University. A hematologist-oncologist and accomplished molecular biologist, Singal has had a
continues to build upon its
distinguished career studying gene regulation in prostate and other genitourinary tumors.
excellent scientific programs
UM/Sylvester currently plans to recruit five additional senior and 25
junior researchers. Each will have significant programmatic involvement
already in place.
within the five scientific programs. In addition, UM/Sylvester has added
new research space, including newly remodeled floors as well as administrative space, to accommodate these additional physicians and scientists.
Under the leadership of UM/Sylvester Director W. Jarrard Goodwin,
M.D., F.A.C.S., and with the full support of our trustees and dedicated
philanthropists in the community, we are well on our way to becoming a
world-class cancer center and achieving NCI designation. We have
embarked on an ambitious program of scientific and clinical expansion
that will transform UM/Sylvester into one of the premier cancer centers
in the nation.
Joseph D. Rosenblatt, M.D.
Scientific Director, UM/Sylvester
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ON THE FRONT LINE
SCIENTIFIC PROGRAMS, SHARED
R E S O U R C E S F A C I L I TAT E D I S C O V E R Y
S
cientists at the University of Miami Sylvester Comprehensive Cancer
Center are grouped into five multidisciplinary scientific programs—
Tumor Cell Biology, Tumor Immunology, Viral Oncology, Cancer
Prevention and Control, and the Clinical Oncology Research Program. These
scientific programs not only address important aspects of the cancer challenge,
they reflect UM/Sylvester’s strengths and priorities as a research institution.
Nine shared research resources are available to all UM/Sylvester members
and provide access to technologies, products, services, and expertise that facilitate interaction between physicians and scientists and enhance scientific
Xiadong Wu, Ph.D., uses BAT to deliver radiation with
productivity.
unsurpassed accuracy.
A brief summary of UM/Sylvester’s scientific programs and shared
research resources follows.
NEW DISCOVERY SHOULD ENHANCE
EFFECTIVENESS OF CHEMOTHERAPY
C
urrent cancer chemotherapy treatment works by attacking rap-
the slow growing tumor cells take up more 2-DG than the slow grow-
idly dividing cells. Fortunately, most normal cells in the body (e.g.,
ing normal cells and consequently starve to death.
organ tissues such as the lung, liver, etc.) are slow dividing, meaning
they typically are not affected by chemotherapy.
Since chemotherapy does not attack slow dividing cells, it also
“Under low oxygen conditions or hypoxia, tumor cells need to
burn more sugar to supply them with the necessary energy to do all of
the things required in the cell,” explains Lampidis.
does not affect the slow growing parts of a tumor, which allows these
Moreover, hypoxic conditions do not allow tumor cells to use other
cells to withstand such treatment once the rapidly dividing cancer
energy sources such as fats or proteins, which normal cells can use
cells have been killed off. This means that although the growth of the
when oxygen is present. This fundamental difference in metabolism
overall tumor can probably be controlled with chemotherapy meth-
opens a window of selectivity that can be exploited by using inhibitors
ods, the cancer is not eliminated or cured completely.
of glycolysis such as 2-DG, adds Lampidis.
Theodore J. Lampidis, Ph.D., a scientist in the Tumor Cell Biology
“When a hypoxic tumor cell’s usage of glucose is blocked with
Program at UM/Sylvester, has discovered one way to attempt to tackle
2-DG it dies, whereas a normal cell that is treated similarly can use
this problem. He has found that since the slow dividing cells located
the other sources of energy to survive,” he says. “Combining 2-DG
in the middle of the tumor are growing under low oxygen conditions
(which targets the slow growing hypoxic cells) with standard chemo-
(hypoxia), they differ in their metabolism of glucose from the normal
therapeutic agents (that attack the rapidly dividing aerobic cells) should
cells in the body. To exploit this difference, he has shown that by sim-
increase the overall effectiveness of cancer chemotherapy.”
ply using a false sugar—2-Deoxyglucose (2-DG)—instead of glucose,
Q U EST
The first clinical trials of this treatment will be available soon.
TH E M A G AZIN E O F TH E U N IVER SITY O F MIA MI SYL VES TER C O MPR EH EN SIV E CA N CER CE N TER
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ON THE FRONT LINE
SCIENTIFIC PROGRAMS
TUMOR CELL BIOLOGY
PROGRAM
Program Leader:
Kermit L. Carraway, Ph.D.
aining a better understanding of
the mechanics of cancer cell biology through cutting-edge research is
just one of the objectives of the Tumor
Cell Biology Program. The ultimate
goal of the program is to develop opportunities for novel clinical applications. Much of the work
conducted within this
program examines how
genetic information in
cells is translated into
functional proteins and
how tumor cells interact
with other cells and their
environment—ultimately
helping scientists better
understand the biology of
cancer, cell proliferation,
and metastasis.
Individual research
within this program
ranges from gene therapy to the ultrastructural analyses of protein, but all
of the investigators are involved in
breakthrough research using the developing methods of molecular biology and cell structural analyses to ask
questions of importance to tumor cell
biology.
Tumor cell biology scientists also
are examining how signaling pathways and molecules transmit and integrate information, which determines
cell behavior and function. By better
understanding how normal tumor
cells behave, UM/Sylvester scientists
can determine whether tumor cell
biology can be targeted to combat
cancer.
G
10
12
Q U EST
TUMOR IMMUNOLOGY
PROGRAM
Program Leader:
Diana M. Lopez, Ph.D.
he Tumor Immunology Program investigates the biology of the immune
system as it relates to the development
and potentially the treatment of cancer.
Currently, the research conducted
varies widely—from measuring breast
cancer patients’ immune system response
T
William J. Harrington, Jr., M.D.
to psychosocial interventions such as
group therapy and stress reduction, to
the design of effective vaccines to fight
various human cancers, to the use of stem
cell and bone marrow transplantation.
Through ongoing research, investigators are gaining a better understanding of the mechanisms underlying
the activities of innate and adaptive immune cells, novel aspects of stem cell
biology and bone marrow transplantation, the role of T cells in the host defenses against tumors, and mechanisms
of tumor evasion of the immune system. Scientists are working to devise
novel immunotherapeutic protocols for
human cancers.
VIRAL ONCOLOGY
PROGRAM
Program Leaders:
William J. Harrington, Jr., M.D.
Antero G. So, M.D., Ph.D.
he Viral Oncology Program is
committed to developing and
implementing novel therapeutic strategies for certain viral diseases and
cancers. Program investigators have discovered that although several forms of
lymphoma and leukemia do not respond to conventional chemotherapy,
they are remarkably sensitive to antiviral therapy. Bench research conducted
by members of the Viral Oncology Program has already translated into new
clinical trials. The program also develops physician-scientists through a National Cancer Institute-sponsored
training grant in viral oncology.
The program’s scientists also conduct clinical and basic research to examine the cellular events that occur
during the process of disease development (pathogenesis) due to oncogenic
viruses such as EBU, HHV8, human
T-cell leukemia viruses, and mechanisms underlying the development of
malignancies in AIDS patients.
T
CANCER PREVENTION
AND CONTROL PROGRAM
Program Leader:
Michael H. Antoni, Ph.D.
ajor research efforts by the Cancer Prevention and Control Program include work in identifying predictors of tobacco use in adolescents;
understanding the ethnic differences in
genetic anomalies connoting risk for
certain cancers; raising awareness of risk
behaviors such as sun exposure that are
associated with the high incidence of
M
TH E M A G AZIN E O F TH E U N IVER SITY O F MIA MI SYL VES TER C O MPR EH EN SIV E CA N CER CE N TER
ON THE FRONT LINE
cancers in Florida; assessment of quality of life among persons who have
been treated for breast or prostate cancer and for those who have become
long-term survivors of cancer; and testing the effects of stress management intervention on psychosocial, endocrine,
and immune system functioning in
persons recently diagnosed and treated
for early stage breast or prostate cancer,
as well as those at risk for AIDS-related
cancers such as cervical cancer. Other
investigations focus on differences in
the incidence of a variety of cancers
among the major ethnic groups residing in Florida, on developing culturally competent outreach programs to
Hispanic populations, and implementing the most effective cancer control
strategies in the South Florida population.
The projects currently being conducted within this program vary sub-
stantially. Some are purely behavioral
or psychosocial in their aims; others
examine neuroendocrine and immunological mechanisms relevant for disease
promotion and/or progression.
CLINICAL ONCOLOGY
RESEARCH PROGRAM
Program Leaders:
Joseph D. Rosenblatt, M.D.
Kelvin P. Lee, M.D.
developing effort at UM/Sylvester,
the Clinical Oncology Research
Program is designed to specifically focus on translational and clinical research in relation to cancer prevention,
diagnosis, and treatment and often collaborates with the four other scientific
programs to ensure timely translation
of basic science and breakthroughs to
the patient’s bedside. Major program
themes include: cellular therapy, gene
A
therapy, developmental therapeutics,
molecular targets/prognostic factors/
pharmacogenetics, and clinical trials.
These efforts link UM/Sylvester’s
basic science discoveries to the bedside
and facilitate the conduct of clinical
trials to gain insights into cancer biology.
SHARED RESOURCES
Cell Purification and Banking Facility
Clinical Research Services Resource
DNA Core Facility
Flow Cytometry Resource
Gene Knockout and Transgene Facility
Histology Research Lab Core
Imaging and Molecular Core
Molecular Analysis Core
Protein Analysis Facility
UM/SYLVESTER SCI ENTI STS IDENTI FY NEW
H O D G K I N ’ S D I S E A S E T R E AT M E N T
S
cientists at UM/Sylvester have developed a new technique to
of the Tumor Immunology Program, and has been licensed for
use the immune system to attack tumor cells. This new treat-
production by Seattle Genetics. It is meant for patients who do not
ment identifies a protein on the surface of Hodgkin’s lymphoma cells,
respond well to traditional treatments for Hodgkin’s disease, which
called CD30, and labels CD30 with an antibody thereby targeting the
include chemotherapy, radiation therapy, and bone marrow trans-
lymphoma cells for destruction.
plants. Unlike chemotherapy, patients treated with SGN30 do not
“We have cells in the immune system that can recognize and
lose their hair and experience fewer side effects.
destroy cells that have been labeled with an antibody that earmarks
Patients are enrolled in phase II clinical trials testing SGN30 at
those cells for destruction,” says Joseph D. Rosenblatt, M.D., scien-
UM/Sylvester and at six other medical centers nationwide. It has
tific director at UM/Sylvester.
already been administered to these patients at UM/Sylvester by Hugo
The discovery of the drug, called SGN30, resulted in the develop-
Fernandez, M.D.
ment of a monoclonal antibody. Because it is an immunological treat-
“CD30 is also seen in lymphoma and myeloma and may poten-
ment, scientists expect fewer side effects than with traditional
tially be useful in the treatment of those types of tumors as well as
chemotherapy. “This type of treatment represents a much more intel-
Hodgkin’s disease,” says Fernandez.
ligent approach to cancer,” says Rosenblatt.
SGN30 was developed by Eckhard Podack, M.D., Ph.D., chairman of microbiology and immunology at UM/Sylvester and member
Q U EST
The phase II portion of the trial with a fixed dose (when the dose
from phase I is used for lymphoma patients to monitor the efficacy of
the drug in the disease) will be available soon.
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ON THE FRONT LINE
SEVERAL NEW PHYSICI ANS AND SCIENTI STS JOIN UM/SYLVESTER TEAM
R
ecruiting prominent clinical researchers to our already distinguished faculty remains a primary focus at UM/Sylvester. The magnitude
of this recruitment effort is so great, in
fact, that 10 physicians and scientists
have already joined UM/Sylvester during FY 2003, while many more have
been recruited and will be featured in
the next issue of Quest.
J
oining UM/Sylvester as an assistant professor of biochemistry and
molecular biology, Terace M. Fletcher,
Ph.D., comes to the cancer center with
seven years of experience in cancer research as a post-doctoral fellow at the
Cancer Therapy and Research Center
Institute for Drug Development in San
Antonio, Texas (headed by oncologist
Daniel Von Hoff, M.D.) and as a staff
scientist at the National Cancer Institute.
As a basic scientist, Fletcher’s research interests include studying the
chromosomal structure called the telomere. The telomere, located at the
chromosome terminus, protects DNA
and regulates cell growth.
According to Fletcher, genomic instability caused by telomere disruption
can result in key genetic alterations and
subsequent cancer transformations. Experimental evidence suggests that telomeres of cancer and normal cells have
architectural distinctions. However, the
structural details of the telomere are
largely unknown.
“Telomeric assemblies found exclusively in cancer cells would present
a set of novel chemotherapeutic targets,” says Fletcher. “The goal of our
laboratory is to explore the relationship
10
14
Q U EST
Terace M. Fletcher, Ph.D.
Elizabeth Franzmann, M.D.
between specific telomeric higher-order configurations and functions such
as chromosome maintenance.”
Fletcher holds a Ph.D. in biochemistry from the University of Texas
Health Science Center.
cation at the University of California
at Los Angeles, where she subsequently received her medical degree.
She completed her otolaryngology
residency and head and neck surgical
oncology fellowship at the University
of Miami.
“Working with a great team is what
makes combining a research and clinical career possible,” says Franzmann.
J
oining UM/Sylvester as an assistant
professor of otolaryngology, Elizabeth Franzmann, M.D., is interested in
all aspects of prevention, diagnosis, and
treatment of head and neck cancer and
will combine her surgical practice, where
she works closely with residents, with
her research interests.
Franzmann is studying the role of
the CD44 family of molecules in head
and neck cancer. CD44 molecules are
involved in normal cell function. In
some tumor cells CD44 molecules are
altered and seem to be involved in uncontrolled growth and migration.
Franzmann completed her basic
science medical school education at
Albert Einstein College of Medicine in
New York, finishing her clinical edu-
C
armen Solorzano, M.D., joins
UM/Sylvester as an assistant professor of surgery. She comes to the cancer center from the University of Texas
MD Anderson Cancer Center where
she completed her surgical oncology
fellowship training.
Solorzano says one of the primary
reasons she wanted to join UM/Sylvester was the opportunity to treat patients of varying geographic and ethnic
backgrounds.
Solorzano plans to explore better
treatments for patients with pancreatic and endocrine cancers. Her prior
TH E M A G AZIN E O F TH E U N IVER SITY O F MIA MI SYL VES TER C O MPR EH EN SIV E CA N CER CE N TER
ON THE FRONT LINE
Carmen Solorzano, M.D.
May Abdel-Wahab, M.D., Ph.D.
laboratory research examined mouse
models for pancreatic cancer. “I will
also be looking at gene expression profiles in patients with thyroid cancer
to better diagnose and treat them,”
she adds.
Solorzano’s other research interests
focus on rapid intraoperative assays to
measure hormones in patients with
overactive parathyroids and insulin tumors of the pancreas. In these patients,
surgical removal of the tumors (overproducing hormones) is necessary, and
these assays assure that all overactive
tissue has been removed.
Solorzano attended medical school
and completed her residency in general surgery at the University of Florida
in Gainesville.
sistant professor of radiation oncology.
Abdel-Wahab trained and held various
affiliate and adjunct positions in the radiation oncology department at the
University of Miami.
At UM/Sylvester, Abdel-Wahab
will continue to work in the areas of
prostate cancer and genitourinary cancers. Her main interest is in the continued study of vitamin D and androgen receptors in prostate cancer. She
also continues her research on the effect of androgen receptor transcriptional integrity on outcome in Radiation Therapy Oncology Group
(RTOG) study patients.
Results of a phase II vitamin D
study headed by Abdel-Wahab,
funded by the VA Research Service,
were presented at the American Society of Clinical Oncology (ASCO) this
year. It suggests a possible benefit in
prevention of recurrence post-prostatectomy. Abdel-Wahab is now preparing
the next step—a study in that group
of patients to determine whether vitamin D will enhance the results of
radiation in these patients. Other re-
M
ay Abdel-Wahab, M.D., Ph.D.,
joins UM/Sylvester as an associate professor of clinical radiation
oncology from the Miami Veterans Administration Medical Center where
she was a research scientist and an as-
Q U EST
search interests include the use of a
novel radiosensitization developed by
Sheldon Greer, Ph.D., at the University of Miami.
Abdel-Wahab has had extensive
training that includes two fellowships
and two residencies at the Crawford
Long Hospital of Emory University in
Atlanta (high dose rate brachytherapy),
National Cancer Institute of Cairo
University in Cairo, Egypt (a recognized leader in bladder cancer treatment), and the University of Miami.
She also has a doctorate from Cairo
University and received specialized
training in gamma knife techniques at
the University of Pittsburgh and seed
implant training at the Seattle Prostate
Institute.
RECENT RECRUITS
2002-2003
T
he following six physicians and
scientists were featured in the
summer issue of Quest.
Izidore Lossos, M.D.
Denise Pereira, M.D.
Rakesh Singal, M.D., M.R.C.P.
Oluwatoyin Shonukan, M.D.
Joyce Slingerland, M.D., Ph.D.
Khaled Tolba, M.D.
TH E M A G AZIN E O F TH E U N IVER SITY O F MIA MI SYL VES TER C O MPR EH EN SIV E CA N CER CE N TER
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15
MILESTONES
June 1992
1992
1993
Sylvester Comprehensive Cancer Center
facility is dedicated and joined with the
University of Miami Hospital and Clinics to
become UM/Sylvester.
Jay Weiss becomes chairman of the board
of UM/Sylvester.
W. Jarrard Goodwin, M.D., F.A.C.S., and
David Stansberry are recruited to provide
faculty and administrative leadership.
LOOKING BACK, MOVING FORWARD
T
he transformation of the University
of Miami Sylvester Comprehensive
Cancer Center into South Florida’s premier cancer center can be traced to its
ability to cope with rapidly changing
environments and situations. This history of flexibility and adaptability has
enabled UM/Sylvester to grow and accomplish significant milestones in a
little more than a decade of operation.
Two months after its doors opened
in June 1992, UM/Sylvester suddenly
found itself confronting a formidable
adversary that put the facility’s continued existence into question.
On August 24, 1992, a massive category four hurricane named Andrew
made landfall in South Florida.
One UM/Sylvester employee present that day was Tom Cunningham, now
associate administrator. “The memory
of that hurricane’s humbling power will
always be indelibly etched in my mind,”
Cunningham says. “As it turned out, Andrew reserved the bulk of its fury for the
Homestead area, and UM/Sylvester
weathered the storm sustaining fairly
minor damage.”
Having survived an encounter
with nature at its most unforgiving,
UM/Sylvester returned to being
10
18
16
Q U EST
buffeted by man-made storms.
“Anytime you create a facility like
UM/Sylvester, there are going to be
growing pains,” Cunningham says.
“Frankly, the first months of operation
were a bit troubling—operating rooms,
for example, were not running anywhere near full capacity. Although
those kinds of issues are to be expected,
they’re still very tough to deal with.”
Eleven years later, inpatient admissions have grown by more than 18 percent
in the past four years alone, and surgeries
have increased by more than 30 percent.
“We’ve grown a lot since the 1990s, and
we’ve reached capacity now. Unless we
increase our bed count and number of
surgery suites, we won’t be able to keep
up with our growing volume,” observes
hospital administrator David Stansberry.
The hospital needs to be expanded
to meet the needs of the ever-growing
patient population. “We’re working to
make the most efficient use of space,” says
Stansberry. “We have a rather significant renovation project underway, and
we’re almost always moving departments
around to accommodate our patients.”
One way that UM/Sylvester may
expand its inpatient and surgical capacity is by moving the Courtelis Center
from its current location to another
floor of the hospital. The Courtelis
Center, which opened in 1995, provides counseling services, patient education and support groups, medication
consultation, patient library/learning
center, and many complementary
therapies for mind and body healing.
“Patients look to us for innovative
new treatments and programs,” says
Stansberry. “The Courtelis Center is
one of our most valuable resources. It’s
but one aspect of UM/Sylvester that
makes us unique.”
In the near future, the Comprehensive Treatment Unit (CTU) is one of the
areas that will be expanded in addition
to the clinical pharmacy area, which is
also running near capacity. “As the
number of chemotherapy treatments
increases, we have to expand our capability in pharmacy as well,” Stansberry
adds. To address these issues, six additional physicians will be hired to the
unit by year-end. “We also have a very
large research enterprise here within the
medical school. An ambitious research
pharmacy expansion is underway that will
increase that area’s capacity four-fold.”
Not all of the improvements are of
the bricks-and-mortar variety, however.
TH E M A G AZIN E O F TH E U N IVER SITY O F MIA MI SYL VES TER C O MPR EH EN SIV E CA N CER CE N TER
MILESTONES
1995
2001
2003
The Courtelis Center for Research and
Treatment in Psycho-Social Oncology
is founded.
Joseph D. Rosenblatt, M.D. arrives
as scientific director.
UM/Sylvester at
Deerfield Beach opens.
The manner in which UM/Sylvester
serves its patients is also being revamped.
“One of the concerns has been that
our services are lacking during nighttime hours,” says Cunningham. “Patients can’t get x-rays or blood work
done, and the pharmacy is closed.”
Consequently, UM/Sylvester has begun to add clinicians and treatment
areas in order to provide full, roundthe-clock care. “Now we offer a full
range of services providing 24-hour
care evenings, nights, and weekends.”
Clearly these are busy, exciting
times for UM/Sylvester, a facility tested
by the force of nature and the needs of
the South Florida community it serves.
“We are committed to ensuring
that the cancer center continues to provide
the highest quality health care to patients
from our region,” Stansberry says.
S TAT E - O F - T H E - A R T I M A G I N G S E R V I C E S
I
n keeping with its dramatic growth, UM/Sylvester continues to offer state-of-theart diagnostic imaging and cancer treatment. Among the services offered at
UM/Sylvester are:
Interventional Radiology
Also known as angiography, interventional radiology is an elegant means of
studying the body’s many blood vessels, along with the organs that they supply.
Radiologists position a narrow tube within the vessel, then inject a special compound that makes the vessel and its surrounding tissue visible on x-ray images.
Stereotactic Breast Core Biopsy
After a suspicious area of the breast is identified on a mammogram, a biopsy is
often done to extract a sample of the abnormal tissue for analysis. The stereotactic unit takes two x-ray images of the abnormal area from different angles,
and a computer then uses those images to determine the precise location in
which to place the biopsy needle.
Positron Emission Tomography (PET)
PET detects metabolic changes in the body’s tissues that may indicate the presence of malignant tumors. PET is especially useful in the detection of malignant, metastatic tumors, those that have spread from the primary site to other
locations within the body.
Multi-Slice Computerized Tomography
R A D I A T I O N O N C O L O G Y: A T E C H N O L O G I C A L L E A D E R
(MSCT)
MSCT takes rapid, cross-sectional
O
ne of the most technologically advanced centers in the Southeast, the Department
x-ray images that can be displayed
of Radiation Oncology at UM/Sylvester offers an extensive variety of treatment tech-
three-dimensionally with startling
niques including Intensity Modulated Radiation Therapy (IMRT) as well as low- and high-
clarity. MSCT enables radiologists
dose rate and intravascular implants of radioactive material (brachytherapy). The
to evaluate the arteries of the heart
department also treats tumors of the eye, orbit, and eyelids and offers eyeplaque
for the presence of calcium, a pos-
brachytherapy (with Bascom Palmer Eye Institute) and is the only institution in South
sible precursor of more serious
Florida to offer total skin electron beam therapy for cutaneous lymphomas.
heart disease.
Q U EST
TH E M A G AZIN E O F TH E U N IVER SITY O F MIA MI SYL VES TER C O MPR EH EN SIV E CA N CER CE N TER
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IN THE NEWS
B R A M A N F A M I LY
BREAST CANCER
INSTITUTE MAKES
EXCELLENT PROGRESS
IN FIRST YEAR
S
ince its inception last fall, the
Braman Family Breast Cancer Institute at the University of Miami
Sylvester Comprehensive Cancer Center—a new institute that combines basic science with clinical trials and
world-class care to discover more effective treatments for breast cancer patients—has witnessed tremendous
advances, thanks in part to an aggressive recruitment effort led by its director, Joyce Slingerland, M.D., Ph.D.
Several new faculty
members have already
been recruited with many
more on the way. Stefan
Glück, M.D., Ph.D., will
soon come on board as
clinical associate director,
coordinating clinical
breast cancer services and
clinical research. Other
hires include new faculty
experts in the areas of
breast radiology, breast
Joyce
surgery, psychological
Slingerland,
support of breast cancer
M.D., Ph.D.
patients, and breast cancer
genetics, to name just a few.
“We have significantly expanded
our therapeutic Clinical Trials Program for
breast cancer patients, and now have 13
therapeutic clinical trials open and another
eight new trials being developed for breast
cancer patients. These are trials of new
drugs and new surgical or radiation
therapy techniques,” says Slingerland.
Institute staff is now carrying out
a clinical trial to test a new method of
breast irradiation that provides a very
10
18
Q U EST
localized radiation treatment to the
breast. A number of molecular targeted
therapies combined with anti-estrogen
therapies are also currently in the works.
The institute also has received
funding from the State of Florida to
expand its community outreach and
patient education arm. The Braman
Family Breast Cancer Institute together
with the Institute for Women’s Health
at the University of Miami will create
this Breast Cancer Education Program
that will have an important focus on
the indigent population.
The Breast Cancer Genetics facility is also expanding, thanks to added
clinic space that was made available by
Jackson Memorial Hospital.
U M / S Y LV E S T E R AT
DEERFIELD BEACH
RECEIVES WARM
WELCOME
R
esidents have embraced UM/
Sylvester at Deerfield Beach, the
cancer center’s satellite facility in northeast Broward County, which officially
opened last January. The warm reception
is an indication of the growing community’s need for such cancer-related services. One of the reasons UM/Sylvester
decided to expand northward was the
fact that approximately 40 percent of
its patients were travelling to Miami
from Broward and Palm Beach counties.
The 10,000-square-foot facility
offers residents of both counties a broad
range of cancer-related services, including
physician office visits, education and
outreach, complementary therapies from
the Courtelis Center for Psychosocial
Oncology, and access to clinical trials.
Due to increasing demand from patients, UM/Sylvester at Deerfield Beach
has added pain management to its lineup
of services. Patients with acute, chronic,
and cancer-related pain now can be
evaluated and treated in both inpatient
and outpatient settings. Diagnostic assessment and a range of invasive and
non-invasive therapies also are available.
Many education and outreach programs are offered at Deerfield Beach
as well. Conversations About Cancer, a
series of free classes and activities given
by physicians and other health care professionals, provides residents information on a variety of topics including
cancer prevention, treatment, stress relaxation, women’s wellness, and many
more. Free health screenings and support groups are also offered here. Since
the facility’s opening, more than 500
residents have benefited from its education and outreach activities.
PAP CORPS GIFT
BREAKS RECORD
C
elebration was in order last May
when the Papanicolaou Corps for
Cancer Research pledged a record-setting $10 million to support cancer research
at UM/Sylvester. As the first major philanthropic announcement for the University of Miami and UM/Sylvester in
Palm Beach County, the generous donation is the largest gift in the history of the
Pap Corps and one that was well received.
The Pap Corps was recently inducted into
the University’s new Miami Society.
The ongoing support of the Papanicolaou Corps, whose headquarters
are now located at UM/Sylvester at
Deerfield Beach, funds critical research
at the cancer center, including work in
tumor immunology, cancer cell biology, and genetics. It also has assisted
investigations of melanoma, ovarian
cancer, and new diagnostic tools for a
variety of cancers at UM/Sylvester.
TH E M A G AZIN E O F TH E U N IVER SITY O F MIA MI SYL VES TER C O MPR EH EN SIV E CA N CER CE N TER
MAKING A DIFFERENCE
MESSAGE FROM THE CHAIRMAN OF THE
BOARD OF GOVERNORS
U M / S Y LV E S T E R
BOARD OF GOVERNORS
Fiscal year 2003
Joaquin F. Blaya, Chair
Diane Abrams
William H. Allen, Jr.
Minor Anderson
Joe Arriola
Cynthia L. Augustyn, J.D.
Jose Bared
Gloria Berkowitz
Minette Brown
Robert Burlington
Ira C. Clark
John G. Clarkson, M.D.
Diane M. Cook
Michael Elliott
Denny Feinsilver
Thomas J. Fitzpatrick
Bernard J. Fogel, M.D.
Gail Gidney
W. Jarrard Goodwin, M.D., F.A.C.S.
Rose Ellen Greene, Vice Chair
Mark Halpern
Peggy Hollander
Sherrill W. Hudson
Thomas B. Levinson, Vice Chair
Alan J. Livingstone, M.D.
Jayne S. Malfitano
Frederick L. Moffat, Jr., M.D.
Eugene K. Montoya
Sharon Pontious, Ph.D., M.S.N.
Joseph D. Rosenblatt, M.D.
John Schulte
Anne Smith, R.N.
Richard Spring
David L. Stansberry
Barbara Weintraub
Jay Weiss
Joined the Board since the
beginning of fiscal year 2004
Michael B. Fernandez
George Mencio, Jr.
Marvin O’Quinn, succeeded Ira C. Clark
Dennis Patin, M.D., succeeded
Frederick L. Moffat, Jr., M.D.
Nilda P. Peragallo, Dr.P.H., R.N., F.A.A.N.,
succeeded Sharon Pontious, Ph.D., M.S.N.
S
ince joining the University of Miami Sylvester Comprehensive Cancer
Center several years ago, I have been pleased to see how far the
cancer center has come and how much we have been able to offer
the community. But there is still so much to do. UM/Sylvester has a
bold vision—to join the ranks of the best cancer centers in the
world—and I am proud to be a part of that endeavor.
Despite an encouraging decline in age-adjusted death rates over
the last decade, cancer will soon replace cardiovascular disease as
Joaquin F. Blaya
the number one killer of Americans. Our population is older than
that of other communities, and, we will have more health problems in the future.
Cancer will surely be one of them. UM/Sylvester’s role becomes even more
imperative: to diagnose and treat patients with cancer and, ultimately, find a cure.
As South Florida’s only university-based cancer center, we are leaders in
research, education, prevention, and delivery of the highest quality patient care.
We are committed to providing state-of-the-art treatment and breakthrough
research, and we owe it to our community to offer that level of service.
UM/Sylvester will soon embark on a capital campaign that will raise the level
of giving. As a board member, I cannot conduct breakthrough research nor can
I treat patients; however, I can join my community in the fight against cancer.
It is philanthropic, corporate, and community support that will help fund
this community treasure going forward. No doubt, with your support, UM/
Sylvester is one of the premier cancer research and treatment facilities in the
nation. Your generous efforts go a long way in reducing the human burden
from cancer in this community, and together we will make a difference.
Joaquin F. Blaya
Chairman of the Board of Governors, UM/Sylvester
Q U EST
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MAKING A DIFFERENCE
S U P P O R T F O R U M / S Y LV E S T E R C O M E S
IN ALL SHAPES, SIZES
A
cross town and across the nation, people from all walks of life are
supporting the search for a cancer cure. Their support comes in
the form of book sales and bake sales, grand balls and grand
slams, and just about everything in between. Whatever the effort, wherever
the stage, one thing remains the same—these folks are doing whatever they
can to help fight a disease that has touched the lives of so many of their families and friends.
While it would be impossible to chronicle all that has take taken place in
the past year to support the important work at UM/Sylvester, we’ve chosen
to highlight a few. They are just a small sampling of the myriad ways so many
people are making a difference at the University of Miami Sylvester CompreTHANK YOU TO THE
S TAT E O F F L O R I D A
O
hensive Cancer Center.
n behalf of our many physicians
and scientists—and our patients,
the direct beneficiaries of our translational research efforts—UM/Sylvester
GALA NETS RECORDBREAKING $1 MILLION
FOR CANCER RESEARCH
wants to thank the legislators and residents of the State of Florida for their support during a very challenging budget
year. The allocation of state funds to the
University of Miami Sylvester Comprehensive Cancer Center has enabled us
to continue our very important work in
the development of cancer vaccines,
biological therapies, and other breakthrough treatments. Furthermore, the allocation for breast cancer research has
allowed us to significantly enhance our
current research initiatives in fighting
this disease. Again, we appreciate your
support and pledge to work each day
to earn it.
10
20
Q U EST
W
ith the generous support and
enthusiastic commitment of
more than 600 South Florida philanthropists, celebrities, and friends, UM/
Sylvester’s biennial “In the Garden” gala
raised more than $1 million to benefit
cancer research. It was a record-breaking night for the cancer center, and one
of the most celebrated events of the
South Florida social season.
Hosted by Gala Grand Honorary
Chairs Fran and Mel Harris, Gala
Honorary Chair Cynthia Davis Carr,
and Celebrity Chair Tara Gilani, the
November 2002 spectacular at the
Fontainebleau Hilton Resort marked
the cancer center’s ten-year anniversary.
Among the evening’s highlights
were the announcement of six new
Founder level commitments and the
presentation of the prestigious Caroline W. Halpern Award to Jay and
Renee Weiss. The gala’s silent auction
featured luxury merchandise donated
by world-renowned retailers, resorts,
restaurants, hotels, cruise lines, and
jewelers.
Of the evening’s memorable moments, none stood out more than the
realization of the tremendous impact
one group of dedicated individuals
can have when it comes to making
a difference in the battle against
cancer.
TH E M A G AZIN E O F TH E U N IVER SITY O F MIA MI SYL VES TER C O MPR EH EN SIV E CA N CER CE N TER
MAKING A DIFFERENCE
ACE!
E
ver since professional tennis coach
Dean Goldfine lost his mother to
breast cancer in 1998, he’s been dedicated to raising funds to fight the
deadly disease. In just three years he’s
raised more than $300,000, of which he’s
donated $200,000 to UM/Sylvester.
From left to right: Amy Martin with son Jackson, Todd Martin,
Dean Goldfine, Jessica Goldfine, Dr. W. Jarrard Goodwin
at the Third Annual Pat Goldfine Tennis Pro Tournament.
The annual Pat Goldfine Tennis
Tournament, now in its third year, pairs
up amateur tennis players with professional male and female tennis players
for a competitively formatted pro-am.
Andy Roddick, Jim Courier, and Mary
Joe Fernandez are just a few of the tennis greats who have participated in the
event. Each year it is followed by a private dinner and live auction for all participants and sponsors.
For two years now, UM/Sylvester
has been the exclusive beneficiary of the
event. This year’s tournament took
place at the Westin Diplomat Resort
and Spa in Hollywood.
Goldfine, who currently coaches
Todd Martin, is recognized as one of
the most successful professional
coaches in tennis. He’s also coached
Aaron Krickstein and Mary Joe
Fernandez.
His fundraising endeavor, a spin
on the sport, is quickly gaining awareness as a smashing success for cancer
research.
J AY A N D R E N E E W E I S S :
2002 CAROLINE W.
HALPERN AWARD
RECIPIENTS
I
t was Bernard Fogel, M.D., dean
emeritus of the University of Miami
School of Medicine, who urged Renee
and Jay Weiss to become involved with
the University of Miami Sylvester
Comprehensive Cancer Center more
than a decade ago. His request was one
that would be met with unimaginable
generosity and selfless dedication.
Renee and Jay Weiss’ passion for the
cause, and their tireless commitment
to helping eradicate cancer and advancing both research and treatment
at UM/Sylvester, made them the natural choice for the 2002 Caroline W.
Halpern Award.
W. Jarrard Goodwin, M.D., F.A.C.S.,
director of UM/Sylvester, bestowed the
highly coveted award upon the Bal
Harbour couple last November at UM/
Sylvester’s biennial “In the Garden” gala.
W O L D E N B E R G F O U N D AT I O N G I F T H O N O R S C A R O L I N E H A L P E R N
C
aroline Halpern was a dedicated supporter of the University of
person,” says Brown. When her mother was di-
Miami Sylvester Comprehensive Cancer Center long before she
agnosed, Brown remembers her words as they
became a patient. In fact, she supported the cancer center financially
walked through the cancer center’s lobby, “She
for years before beginning her own four-year battle with lung cancer.
said, ‘I was on the ground floor of all this, but I
As an administrator of the Woldenberg Foundation, a New Orleans-
never dreamed I would be a patient.’”
based foundation established by her uncle, Malcolm Woldenberg,
Halpern was introduced to the cancer cen-
Halpern helped direct an annual donation to the cancer center. After
ter by long-time family friend Jay Weiss. Brown
her death just six years ago, her children have carried on the support
says once he told her the story of the facility—then called the Papanico-
in the form of a donation in their mother’s honor. To date, that support
laou Cancer Research Institute—and brought her in, she was hooked.
has amounted to more than $1 million.
Minette Brown
Halpern’s support of the cancer center was so meaningful, the
“My mother was so committed to UM/Sylvester,” says Minette
hospital established an award in her name, the Caroline W. Halpern
Brown, Halpern’s daughter who lives in Plantation, Florida, and sits on
Award. She was the first recipient of the annual award, followed by Bar-
the foundation board with her brother, Mark Halpern, of Surfside. “We
bara Weintraub in 1994, Cy and Helene Somerstein in 1996, the
do everything we can to perpetuate the gift.” Brown and her brother
Grossman Family in 1998, and Jay and Renee Weiss in 2002.
also sit on UM/Sylvester’s Board of Governors.
“She was a major supporter, yet a very private and very humble
Q U EST
“She really cared about UM/Sylvester,” says Brown. “She really
made a difference.”
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MAKING A DIFFERENCE
Established in 1994, in honor and recognition of Caroline Halpern’s commitment to supporting cancer research,
the award recognized the true sense of
giving back to the community. Giving
Jay and Renee Weiss with University President
Donna E. Shalala
back is what Renee and Jay Weiss seem
to do best.
“Jay has been a phenomenal driving force behind the cancer center; he
has been an unparalleled spokesman on
our behalf,” says Goodwin. “His vision
and leadership have invigorated and inspired us to reach new heights.”
Jay Weiss, a founding executive
with Southern Wine and Spirits, has
generously given his time and financial support to the University of Miami, and particularly UM/Sylvester. He
served as chairman of the Board of
Governors of UM/Sylvester for eight
years, and is a past chairman of the
Miami-Dade County Public Health
Trust, which oversees
Jackson Memorial Hospital. He currently serves
on the University of
Miami’s Board of Trustees and his wife is a
Grand Founder of UM/
Sylvester.
The Weiss family
firmly believes in UM/Sylvester and understands Gloria Berkowitz
10
22
Q U EST
the vital need for a world-class cancer
treatment and research facility here in
South Florida. Their efforts are focused
on helping improve early detection and
better treatment today, while achieving their dream of one day eliminating
death from cancer. They recognize the
absolutely critical role that funding
plays in realizing their goals.
The spirit of philanthropy runs
deep in the Weiss family. Renee and
Jay’s four daughters also are actively involved in a number of charitable and
community activities. They are determined to carry on the family tradition
of giving back and setting an example
for their own children.
“To say they are charitable is an
understatement,” says Fogel. “They care
so much about people, especially those
who are not as fortunate as others. Anything they can do to help, they do.”
GLORIA BERKOWITZ,
PRESIDENT OF
THE PAPANICOLAOU
CORPS
G
loria Berkowitz, president of the
Papanicolaou Corps for Cancer
Research, has a vision. Her hope is that
one day the organization she represents
will cease to exist because a cure for cancer will have been found.
It’s certainly not unthinkable, especially after the Pap Corps
donated $2 million and
pledged a record-setting
$10 million over the
next five years for research
efforts at the University
of Miami Sylvester
Comprehensive Cancer
Center last May.
“Cancer is something that affects every-
body, whether directly or indirectly—
it affects you no matter what,” says
Berkowitz, president of the Pap Corps,
a volunteer group with 13,000 members across four counties that has supported cancer research at the University
for 51 years. “A lot of our members are
survivors,” adds Berkowitz. “Our members truly believe, and I believe, that
the cure will only come from research.”
“Research cures cancer, and no
group works harder than the Pap Corps
to support that effort,” says W. Jarrard
Goodwin, M.D., F.A.C.S., director of
UM/Sylvester.
The ongoing support of the
Papanicolaou Corps funds critical
research at UM/Sylvester, including
work in tumor immunology, cancer
cell biology, and genetics. It has
also assisted investigations of melanoma, ovarian cancer, and new diagnostic tools for a variety of cancers at
South Florida’s only university-based
cancer center.
“Whether it’s members sitting
with the Cans for a Cure in front of
Publix or running a golf and tennis
tournament that makes $150,000, it
all comes together,” Berkowitz adds.
“There would be no Corps without the
members, and they each have their own
way to get to the goal—funding cancer research.”
DENNY AND PAUL
F E I N S I LV E R
W
hen Denny Feinsilver puts her
arms around something, her
heart tends to follow. That’s when the
act of getting involved explosively shifts
from generous support to full-fledged
activism.
“If there was anything in the world
we wanted to be involved in, it was
TH E M A G AZIN E O F TH E U N IVER SITY O F MIA MI SYL VES TER C O MPR EH EN SIV E CA N CER CE N TER
MAKING A DIFFERENCE
cancer research,” says Denny. “Research
is the only thing that will cure cancer.
By getting involved, we’re protecting
our future—our families, our colleagues,
our friends, and our community.”
Her husband, Paul, is
behind her every
step of the way.
In just four
years, the Feinsilvers have rooted
themselves in the
cancer center,
becoming founding members of
Friends for SylDenny and Paul Feinsilver
vester. Together,
they sit on the
boards of Friends for Sylvester and the
Founders’ Society, which Denny now
co-chairs.
Ironically, on the day they were
named to the Founders’ Society, cancer
touched their lives in a personal way.
The experience solidified their belief
that UM/Sylvester is one of the top
cancer centers in the world, and today,
the Feinsilvers are Grand Founders.
When it came time to celebrate the
successful outcome of their personal experience with cancer, Denny launched
Coupons for a Cure. The successful
fundraising program she developed
turns the thoughtful deed of gift giving into a meaningful opportunity to
support cancer research. In its first full
year, the program generated 132 coupons (or donations to the cancer center). Just two years later, the number
rose to 1,300, a figure Denny predicts
will exceed 2,000 this year.
“It’s a simple, user-friendly program,” she says, “that is not only selfperpetuating in its growth, but also is
enhanced by additional programs dur-
Q U EST
ing the holidays as well as displays at
local businesses.”
In 2001, Denny chaired the inaugural Live on Lincoln, a major biennial
Friends event that raises funds for cancer research through a celebrity performance, an exclusive pre-theater dinner,
and a spectacular live auction. This
year’s event (November 13), which
Denny will chair again, features renowned actor Tony Danza, and is expected to raise more than $250,000 for
cancer research.
“This is an institution we believe
in,” says Denny. “We’re committed to
more than just financial support. We’re
committed to getting the word out and
marketing the cause. We want to let
people know how very fortunate they
are to have UM/Sylvester in their own
backyard.”
THE BERNICE KRASLOW
OVARIAN CANCER
RESEARCH FUND
W
hen UM/Sylvester physicians
diagnosed Bernice Kraslow
with third-stage ovarian cancer in
1990, both she and her husband, University of Miami Life Trustee and Public Health Trust Board Member David
Kraslow, were shocked.
“They call this the silent disease of
women because it usually produces few
symptoms,” says Hervy E. Averette,
M.D., American Cancer Society professor of oncology, Division of Gynecologic Oncology at UM/Sylvester.
Then, of course, came the questions. What were her treatment options? What were her chances for
recovery? What next?
“The initial diagnosis was that she
would live another two to three years.
She might live longer or less. There was
no guarantee,” recalls David Kraslow.
“Fortunately, she was a fighter. She received superb care at UM/Sylvester,
and she lived another 12 years.”
Standard therapy for advanced
ovarian cancer involves surgery, followed by chemotherapy. According to
Averette, Bernice’s doctor, extensive
surgery was performed to remove the
bulk of the tumor. In addition to follow-up surgeries, she was placed on a
dozen different types of regimens of
chemotherapy and drugs over the next
12 years. Bernice responded well to the
treatment most of the time.
“The uniqueness of this case was
that Bernice Kraslow was tough; she
was a fighter and as feisty as anyone I
have ever seen,” recalls Averette.
“Bernice hung in there—I don’t think
that I ever made a suggestion that she
didn’t follow.”
During her 12-year bout with the
disease, Bernice didn’t sit idly by. Determined to help other women in the
same situation, she created a forum at
UM/Sylvester to allow
cancer patients to support each other through
knowledge and hope.
She also fielded calls
from women from
around the country who
called her to share their
experiences, often finding
inspiration in Bernice’s
remarkable story of sur- David Kraslow
vival. Her efforts even
caught the eye of cancer center staff,
who presented Bernice with a business
card that read: Bernice Kraslow, Cancer Educational Consultant.
“Bernice asked a lot of questions
after the first surgery and started researching the disease and talking to
people,” recalls Kraslow. “That’s when
TH E M A G AZIN E O F TH E U N IVER SITY O F MIA MI SYL VES TER C O MPR EH EN SIV E CA N CER CE N TER
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MAKING A DIFFERENCE
she decided that she would be a source
of knowledge for other women with
ovarian cancer.”
Bernice had a severe setback in July
2001, and she agreed the time probably had come to engage hospice. But
she rallied remarkably, tore up the hospice papers, and survived another year
with a reasonably good quality of life.
She died in July 2002.
“She was a survivor,” says Averette.
“She had the perfect positive attitude
to do what she had to do to be with her
family until the very end.”
In memory of Bernice and her tireless efforts to help others, the family
created a fund in her name for contributions to cancer research—the Bernice
Kraslow Ovarian Cancer Research Fund.
“Both Bernice and
I were determined to
create a program to support research at UM/
Sylvester,” says Kraslow,
“and at the time of her
death, I was convinced
that this was the thing R. Kirk Landon
to do. This fund is in
concert with everything that she had
done during the course of her illness.”
Kraslow, in fact, believes wholeheartedly that more individuals should
support cancer research. This notion
has even trickled down to other members of his family. For his Bar Mitzvah
project, grandson Ryan Dandes solicited collectibles from the Hurricanes
and other sports teams, which he
raffled off to raise money for his
grandmother’s fund. The effort raised
more than $600.
“Not only did we create the fund
as a way to memorialize Bernice, it was
a way of creating a vehicle to support
10
24
Q U EST
research dedicated only to ovarian cancer,” says Kraslow. “It’s not a closed
fund by any means; we welcome any
penny that comes in.”
R. KIRK LANDON
R.
Kirk Landon truly believes in
cancer research and feels strongly
that South Florida deserves a worldclass cancer research center. So strongly,
in fact, that he’s put the financial support of his family’s foundation behind
the facility he says is among the best in
the Southeastern United States.
Landon understands that research
is what ultimately will find a cure for
cancer. And, he knows
that financial support is
key to advancing that
research. Thus, when
charged with the responsibility of administering the Kirk A.
and Dorothy P. Landon
Foundation, Landon
approached UM/Sylvester about establishing a prize program for
cancer research. The
foundation was established by a bequest from his stepmother who willed
that her estate be committed to medical research, especially cancer research.
That meeting, and several that
followed, became the foundation for
the Landon-AACR Prizes for Cancer
Research, two of the world’s most lucrative prizes for cancer research. Early
next year, UM/Sylvester, along with the
Landon Foundation, will host the second annual ceremony awarding two,
$200,000 prizes for cancer research.
The first will be given to Charles J.
Sherr, M.D., Ph.D., from the Howard
Hughes Medical Institute, who will
receive recognition for basic cancer
research in the area of tumor cell biology. The second, for his work in translational cancer research, will be given
to Dennis J. Slamon, M.D., Ph.D.,
from the Jonsson Comprehensive Cancer Center at UCLA. The 2004 event
will take place January 16.
As part of the program, and because
of Landon’s deep regard for the important work under way at UM/Sylvester,
the award recipients spend time in
Miami exchanging ideas with UM/Sylvester faculty. Landon realizes it is UM/
Sylvester that is truly advancing cancer
research in the region, something he believes is absolutely vital to the well being of the community, which he adores.
“UM/Sylvester has recruited some
of the country’s most outstanding cancer researchers,” he says. “As they continue to add to that program, they will
continue to do more and more in the
fight against cancer.”
Landon says giving “constantly
and continually” to cancer and cancer
research is essential. “The more we can
do, the better we can be,” he says. “When
it comes to cancer, it’s not a question of
if, it’s a question of when. The numbers
are staggering; everyone has had some
kind of cancer experience, somewhere
in their family.”
Landon praises the recent strides
made at UM/Sylvester to advance basic
and translational research.
JOHN AND JUDY
S C H U LT E
I
t takes a few tries to get John Schulte
to agree to talk about the contributions that he and his wife, Judy, have
made to the University of Miami
Sylvester Comprehensive Cancer Center. He shies away from the spotlight,
TH E M A G AZIN E O F TH E U N IVER SITY O F MIA MI SYL VES TER C O MPR EH EN SIV E CA N CER CE N TER
MAKING A DIFFERENCE
uncomfortable discussing the business
acumen that has allowed him to be a
donor today. Ignoring the Schultes’
story, though, would mean missing the
chance to bring attention to this
couple’s strong belief that people need
to get involved and stay involved.
“John is extremely private about his
involvement,” says Joaquin Blaya, chairman of UM/Sylvester’s Board of Governors. “But his commitment is unbelievable. His actions are a stronger statement
than anything that could be said verbally.”
Since becoming members of the
Founders’ Society five years ago and
more recently the Ashe Society, John
and Judy Schulte have become an impressive force in the fight against cancer. Each year, the Schultes contribute
to cancer research in the hope that others will benefit from their gifts. Their
goal is to renew their Founders’ Society membership each and every year.
When John was named to the Board
of Governors last year, he renewed his
commitment to help improve every
facet of cancer care at UM/Sylvester.
“We consider ourselves to be very
ordinary people who live very private
lives,” John says. “Along the way, we have
been blessed to be able to make extraordinary contributions to such an important cause.”
Judy and John Schulte
Q U EST
T H E S P R I N G F A M I LY
I
life. Today Jeanne is cancer-free, enjoying her family and new grandchild.
“No question, the best line of attack is going to a major medical center,” says Richard. “For those living in
Florida, UM/Sylvester is the place to
go to get the best, state-of-the-art treat-
n 1989, Jeanne Spring was diagnosed with squamous cell cancer.
Following surgery, chemotherapy, and
radiation therapy, multiple complications developed. During the next four
years, the Spring family spent endless hours
waiting to see the best
doctors New York had
to offer.
“When a person
is informed they have
cancer, after the initial shock, they think
in terms of finding
the best medical care
possible. Many think
of going North to a
well-known hospital,” says husband
Richard. “Our personal experiences show Left to right: Jennifer Spring, Jill and Adam Spring, Jeanne and Richard Spring,
this may not be the Jean Marc de Silva, and Daniel Spring.
best. The renowned
hospitals are often overcrowded and ap- ment, as well as providing your loved
pointments are difficult to get.”
one with the best chance for recovery.”
In 1994, Jeanne and Richard moved
In gratitude, the Spring family has
to Boca Raton. At that time, Jeanne’s donated to UM/Sylvester substantially
condition worsened, requiring exten- in both money and effort. Richard sits
sive surgery. She was cared for by a on the Board of Governors, the Sciennumber of doctors and hospitals in tific Steering Committee, and chairs
Boca Raton and Fort Lauderdale— the Cancer Research Committee. Chileach prescribing different medications dren Daniel and Jennifer are involved
and treatments—but her health with Friends for Sylvester. Richard and
steadily deteriorated. At that point, ev- Jeanne were inducted into the Ibis Soeryone had just about given up hope. ciety last year, and this year Daniel and
At the suggestion of a friend, the Jennifer became Grand Founders. Son
Springs scheduled an appointment Adam and wife Jill are Founders and
with a team of physicians at UM/Syl- soon will become Grand Founders.
vester. These doctors performed addiTo date, the Spring family has dotional surgery, and oversaw her treat- nated more than $500,000 to fund
ments and medications.
UM/Sylvester’s cancer research effort,
The coordinated team approach all with the hope of helping others, just
worked. This team of doctors saved her as they were helped.
TH E M A G AZIN E O F TH E U N IVER SITY O F MIA MI SYL VES TER C O MPR EH EN SIV E CA N CER CE N TER
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MAKING A DIFFERENCE
STRENGTH IN NUMBERS
This listing is representative
of gifts received during
June 1, 2002 – May 31, 2003.
B
elow is a listing of the generous men and women, foundations and corporations, who link the South Florida community with its only university-based,
research-oriented comprehensive cancer program. Together, we are reducing
the burden of cancer for patients and their families in South Florida.
$2,000,000
$15,000 - $24,999
Papanicolaou Corps for Cancer
Research, Inc. (Merrick)
Robert A. & Gertrude Barnett Foundation
Louis Ducoff
First National in Palm Beach
Greater Miami Jewish Federation
Herbert and Susen Grossman (Ibis)
Joan Levy Cancer Foundation
Thomas B. and Sandy Levinson (Founder)
Lillian Lowen
Mellon United National Bank
Florence Mufson (Founder)
The Stephen Muss Foundation, Inc.
(Founder)
Bill and Irene Panoff/PPI Group
Gerald and Joan Robins (Grand Founder)
Richard H. Simons Charitable Trust
(Grand Founder)
Harcourt M. & Virginia W. Sylvester
Foundation, Inc. (Merrick)
Women’s Cancer Association of UM
(Merrick)
Women’s Cancer League of Miami Beach
& Greater Miami, Inc. (Ashe)
$1,000,000
Norman and Irma Braman Family
Foundation (Merrick)
$100,000 - $249,000
The Applebaum Foundation
Dorothy Besserman (Grand Founder)
Estate of Sherlock Hibbs
William G. and Alice Pannill
(Grand Founder)
Ronald A. Silver Charitable Foundation, Inc.
John K. and Judy Schulte (Ashe)
Richard and Jeanne Spring (Ibis)
Woldenberg Foundation
$50,000 - $99,999
Harvey R. and Roberta Chaplin
(Grand Founder)
Colson Hicks & Eidson
Dade Community Foundation
Steven Dwoskin (Founder)
Jewish Communal Fund
Mel and Fran Harris Foundation
(Grand Founder)
Sherman Simon (Grand Founder)
United Way of Miami-Dade
$25,000 - $49,999
ASCPA (American Society of
Composers, Authors and Publishers)
Joaquin F. and Isabel Blaya
(Grand Founder)
John and Barbara A. Cirino (Founder)
David and Isabel Etter (Founder)
Fontainebleau Hilton Hotel & Resort
Estate of Will Hudson
John McGuire*
Stuart Miller
Morgan Stanley
Northern Trust Bank of Florida N.A.
(Founder)
Mario C. Rodriguez (Founder)
University Shopping Center
Bruce Weber
10
26
$10,000 - $14,999
John and Susan Adams (Founder)
Anilam Acu-Rite
Ansin Foundation
Jerry and Nancy Blair
The Cejas Family Foundation, Inc.
(Founder)
Chartwell Charitable Foundation
Zita Danoff (Founder) *
Eagle National Holding Company
Farnsworth Farms
Paul and Denny Feinsilver
(Grand Founder)
Terry & Linda Fenner
First Miami Securities, Inc. N.M. B.
Joel and Paula Friedland (Founder)
Gerald and Rose Ellen Greene (Founder)
Allen and Jill Greenwald
Halogenetics, Inc.
Thomas and Sherry Ireland
James and Diane Klotz (Founder)
David Kraslow
Christopher and Jayne Malfitano
Alvin I. and Nancy Malnik (Founder)
Oceanview Club Development Co. LLC
Pfizer, Inc. Corporate Affairs
PharMed Group Corp.
Podhurst Family Foundation, Inc.
(Founder)
Steven Posner (Founder)
Q U EST
Mark S. and Susan Rodack (Founder)
Sands Brothers
Rowland and Sylvia Schaefer
J. David and Joan Scheiner (Founder)
Lois H. Siegel
The David & Susan Strauss Foundation,
Inc. (Grand FFS)
Phillip and Eileen Youtie (Founder)
The Yulman Foundation (Founder)
United Automobile Insurance CO. (FFS)
Vanneck Bailey Foundation (Founder)
Jay Weiss Family Foundation Inc.
(Merrick)
$5,000 - $9,999
Michael and Judy Adler
Amadeus North America, Inc.
Ray and Nancy Anderson
Garner Anthony
Cara and Bobby Balogh Family
Foundation (Founder)
Fred and Marilyn Berens (Founder)
Terry L. Cardwell (Grand FFS)
Codina Group, Inc.
Commercial Bank of Florida
Wileen Coyne
Daughters Of Penelope Grand Lodge
Sonja Eiteljorg (Founder)
Samuel and Freda Epstein (FFS)
Estate of Will Hudson
Federated Stores
Ginger Spirits, Inc.
W. Jarrard & Sharon Goodwin, Jr.
(Grand Founder)
Jesse Gottlieb
Mary M. Graham
Green Family Foundation (FFS)
Louis and Evelyn Grossman (Founder)
Peggy Hollander (Ibis)
Benjamin and Rita Holloway (FFS)
H. I. G. Capital Management, Inc.
Ingrid Hunter
Jacksonville Greyhound Racing
Bruce and Deborah Kaye
Donald and Eileen Kramer
Bowen A. Arnold and Trude Koby (FFS)
Ella Kugelmann
Edward & Bloosom Leibowitz Family
Foundation, Inc.
Ronald Levy
Estate of Frank J. Lewis
Thomas and Sandy Levinson (Founder)
Charles J. Lopiccolo
Ruben and Denise Lujo
Merrill Lynch Trust
Eugene K. and Jimmie Montoya (Founder)
Ocean Bank
Oren Development Corp.
Terrence M. O’Grady (FFS)
Rafael and Alexandra Ordonez
Bruce Ovitz
Alan Richardsen
The Rubach Family Foundation (Founder)
Pete and Susan Sibley
Norman Shulevitz Foundation
Lewis and Eileen Silberman
Robert D. and Sheila Slewett (Founder)
William D. and Jean Soman (Founder)
Southern Wine & Spirits of America, Inc.
Daniel Spring (Founder)
Jennifer Spring (Founder)
Standard Broadcasting Corporation Ltd.
Sylvester Socialites
Ilene F. Tessler
C. Thomas and Donna Tew
Tropic Supply, Inc.
Ruth Wagner (Founder)
Geoffrey S. Weisbaum
Sherwood M. and Judith Weiser (FFS)
William J. Whelan
Young Family Foundation (Founder)
Y.S. Liedman & Associates
$2,500 - $4,999
Michael and Diane Abrams (FFS)
AHEPA National Housing Corp.
Ruby M. Bacardi
Gail and Antoniette Baldwin (FFS)
Bank of America
Joel and Susan Barnett
Donald and Geraldine Bohning
Burdines, Inc.
Charitable Gift Fund
Andy M. Custer
Downrite Engineering Corp.
David and Beth Ertel (FFS)
Scott Feder
Jack and Mindy Finkelman
Abbey Glassman
Michael A. Gott
Herschel and Nancy Green
Maurice and Sonya Greenfield
Jon Greenwell
Jerome J. and Honora Grossbardt
Hanzman Criden Chaykin & Rolnick, P.A.
Florence Hecht
Eugene J. and Elsie Howard (Founder)
*deceased
TH E M A G AZIN E O F TH E U N IVER SITY O F MIA MI SYL VES TER C O MPR EH EN SIV E CA N CER CE N TER
MAKING A DIFFERENCE
Elmer A. and Roslyn Hurwitz (Founder)
Jacobson Properties
Craig M. and Martha Johnson
Michael D. and Susan Jones
Brian King
William and Carole Landa
Hal and Rita Leeds
Mark and Suzanne Levitats (Founder)
Alan R. and Diane Lieberman
The Mailman Foundation, Inc.
Marion A. Roletti Foundation Inc.
Mark J. Gordon Foundation
Miles A. and Patty McGrane III
Rolf Meijer-Werner
Peter and Marion Mosheim
Jeff and Selma Newman (Founder)
Pershing Industries, Inc.
The Potamkin Foundation (Founder)
Benton and Ronnie Pumpian
Harvey and Theodora Robbins (FFS)
Harry and Ronni Shier (Founder)
Michael A. and Peggy Silver
Peter B. Simel
Glenn H. Singer Family Foundation, Inc.
Standard Pacific Corp.
Technion Communications Corp.
Thomsen Foundation, Inc.
Grant Thornton
Vintage Homes Of Parkland, Inc.
Irving and Kay Waltman
Alan and Patty Weinstein (FFS)
WFOR-TV
Williams Island, The Florida Riviera
$1,000 - $2,499
Africk Family Foundation Inc.
Samuel I. Adler Family Supporting
Foundation
Jonathan and Bonnie Aibel (FFS)
Akerman Senterfitt
Jon and Shirley Alexiou (FFS)
Allstate Giving Campaign
Ritchie and Barbara Ambers
American Italian Association
American Research Kemicals
Peter Andolina
Anonymous
Barbara Cox Anthony Foundation
Aventura Orthopedicare Center
Cara Balogh (Founder)
Bank One Corporation
Bank United
Alberto and Alegre Barrocas
George L. and Ellen Baum
Gary and Patricia A. Becker (FFS)
BET Miami Greyhound Partnership
Tito and Monica Betancourt
Bernie Bercuson
Steven Bernstein
Donald and Suzanne Bezahler
Andrew Blum
Bonnie & Ilene Inc.
Mark and Carol Brooks (FFS)
Artie and Susan Brown
Bruce and Jacquelyn Brown (FFS)
Brown Jordan International, Inc.
Robert and Alden Burlington (FFS)
Calamos Asset Management, Inc.
Camner Family Charitable Foundation
Campaign to Re-elect Judge
Ronald M. Friedman
Edward J. and Susan Capuano
Q U EST
Carl’s Furniture, Inc. (Founder)
Cesar E. and Claire Ceballos (FFS)
Joe Chang
Jerome and Jacqueline Chaves
Geraldine V. Chavez
Louis J. and Rosemarie Ciccotto
Cobb Family Foundation
City First Mortgage Corp. (FFS)
Kendall and Joni Coffey
Arthur and Diane Cohen (FFS)
Rita & Jerome J. Cohen Foundation, Inc.
Michael A. Comras and Susan Hally (FFS)
Robert and Fredi Consolo (Founder)
Credit Suisse First Boston Corporation
Michael and Michele Criden (FFS)
Glenn and Michelle Cutler (FFS)
Steve and Arlyn Cypen (Founder)
Dauer Family Foundation
James W. Davidson
Alicia M. Dahling (FFS)
Dean and Kayrn Dekker (FFS)
Leslie Delman
Drehl & Larison, P.A.
Dianne Dimond
Warren and Carolyn Dodd
Leonard and Adele Dublin (FFS)
William G. and Cassandra Earle (FFS)
Alex and Mary Claire Espenkotter (FFS)
Jeanne-Marie Fascell
Richard and Colleen Fain (FFS)
Miguel and Nelly Farra (FFS)
George Sparrer and LaReine R. Fedor (FFS)
Michael and Clara Felsher
Sanford Fenster
Jose M. and Lilia Fernandez
Fiber Seal of N.Y.
Ted and Jeanette Fine
Elaine Fink
Iris Fisher
Flagship Resort Development Company
(Founder)
Robert and Nancy S. Frehling (Founder)
Albert and Muriel Freund
John and Bonnie Gaebe
Harold and Jill Gaffin (FFS)
Richard and Barbara Garrett (FFS)
B. Milfred Gerson
Barry and Linda Gibb
Jeff and Gail Gidney (Founder)
Justin J. Gimelstob
Glassman Development (FFS)
Maynard Goldberg
Frank Gomez
Maida Gordon
Greenhill & Co., L.C
Grossman & Roth, P.A.
Steven and Wendy Gurowitz (Founder)
Susan Gutman (FFS)
Mark M. and Margaret Halpern
Michael A. and Reva Hanzman (FFS)
Jeannette G. Harris (Founder)
Tim Henman
Paul and Susan Herman (FFS)
Samuel and Barbara Herzberg
Jeffrey Herzfeld
Thomas and Kathy Hewitt (FFS)
Mark and JoAnn Hildebrandt (FFS)
Walter and Barbara Hinterkopf (FFS)
David Stone and Sheri Hirschfield
Hite Foundation
Martin and Geraldine Hoffman
Robert and Christy Hoffman
Daniel M. and Toni Holtz (FFS)
Laurie Holtz
Robert and Virginia Horner*
Scot L. and Barbara Hunter
Garry J. Hurewitz
IDS Telcom
Richard and Marilyn Jacobs
Craig M. and Martha Johnson
K. Phillips & Co. Inc.
Marc and Lori Kahn (FFS)
Martin Kalb (FFS)
Frank and Missy Kardonski (FFS)
Jack and Arden Karson (FFS)
Katcher Family Foundation, Inc.
Katz, Kutter, Alderman, Bryant & Yon
Charles D. Kelman
Eugene and Lois Kessler (FFS)
Herman H. Klorman
Alan Kluger and Amy Dean (Founder)
Robert and Gloria Kolikof
Michelle R. Krinzman
Richard C. Kronrad
Richard J. and Susan Lampen (FFS)
Larise Realty Group, Inc.
Alan and Alice Lash (FFS)
Everett and Lynne Lassman
Albert & Temmy Latner Family Foundation
Michael and Alexa Lazarus
Stephen and Terri Lazarus (FFS)
Leesfield Family Charitable Foundation Inc.
David and Bette Lehman
Lehman Dealership Enterprises, Inc. (FFS)
Allen and Kathy Levi
Meron and Carol Levitats (FFS)
Sidney and Sandra Levy
Daniel and Jan Lewis (Founder)
James G. and Phyllis Lippman
Lloyd/Flanders Industries, Inc.
Carlos and Amada Lopez-Aguiar
Lucky Brand Dungarees of America, Inc.
Heinz and Marianne Luedeking
Leo George and Mary Ellen Lynch (FFS)
H. Larry and Penny Mager (FFS)
Frances Maichin
Manulife Financial
Masarek Family Foundation, Inc.
John McCarthy
McCrea Foundation
Victor and Lisa Mendelson (FFS)
Minto Foundation, Inc.
Fernando and Lynn Elena Miranda (FFS)
George J. Mitchell
Ricky and Amy Mittelberg (FFS)
Paul and Adrianne Mittentag
David and Tracy Moret (FFS)
Ewan C. Moffat
Melvin and Elaine Morse (FFS)
Mirtha Orue Muller (FFS)
Neiman Marcus
Craig and Deirdre Nash (FFS)
Steven W. Neckman
Northwestern Mutual Foundation
Scott and Shari Notowitz (FFS)
Yair and Frieda Oren (Founder)
Pallant Spring & Grace
Gonzalo Parodi (FFS)
Mary Carr Patton
Ray H. and Georgia Pearson
Michael and Karen Pernick (FFS)
Joel S. and Jean Perwin (FFS)
Richard and Erin Pfenniger (FFS)
Philips Medical Systems North America Co.
TH E M A G AZIN E O F TH E U N IVER SITY O F MIA MI SYL VES TER C O MPR EH EN SIV E CA N CER CE N TER
Lester N. and Mary Pokorne (FFS)
Richard H. Pollak
Bruce W. Polozker
John and Laura Pomerantz
Irwin and Linda Potash
Premier Parking Management, Inc. (FFS)
Premier Wine & Spirits
Michael and Lisa Puder (FFS)
Arthur Queler (FFS)
Rick Quintner
Peter Cassileth and Judith Ratzan (FFS)
Lillian Redlich
Nathan and Carolee Reiber
Charles and Valerie Riback (FFS)
Richmond Jewish Foundation
Alan Richardson (FFS)
Norman and Myrna Ricken (FFS)
Victoria J. Rogers (FFS)
Roepnack Corporation
Saul J. Rosen
Stanley M. and Susan Rosenblatt
Robert and Jill Rosenhaus
Rosenstiel Foundation
Claire M. Rotella
Mark and Tobi Rousso (FFS)
Sam and Dorothy Rubin (FFS)
Raquel Rydz
Saks Fifth Avenue-Bal Harbour (Founder)
Salomon Smith Barney, Inc.
Guillermo and Irma Sanabria
Sanford Fenster
San Jose Mercury News
Douglas J. Sanders (FFS)
Scharlin Family Foundation (Founder)
James J. Schlesselman
David and Stephanie Schwartz (FFS)
Joseph and Gail Serota (FFS)
David and Liliy Serviansky
Daniel and Rita Shapiro
Hy and Sheila Shapiro
Sherry Shariatmadar
H. Allan Shore (Founder)
Dorothy Sibley (FFS)
Scott A. and Susan Silver (FFS)
Joseph Esformes and Kathy Simkins
Richard Simon
Guy and Teresa Skellenger
Alan M. Slewett (FFS)
Nancy Smith
Songwriters Guild of America
South Beach Insurance Agency, Inc.
George Feldenkreis and Maria Srebnick
Sterling USA, Inc.
Tibor and Hana Stern (FFS)
Sweet Paper Sales Corp.
James D. and Janie Tate (FFS)
Tate Enterprises
Technical Olympic, USA, Inc.
Todd and Desiree Tennen
Maurice W. and Betty Terkel (FFS)
Peter and Paula Trematerra (FFS)
Denis P. and Linda Trupkin
Harry N. and Alina Turk (FFS)
Rita Ullman
Joseph Weintraub Family Foundation,
Inc. (Grand Founders)
Union Bank
United Way of Broward County, Inc.
US Bank
Vanguard Charitable Endowment Program
Manuel and Carmen Villamanan (FFS)
*deceased
10
27
MAKING A DIFFERENCE
Diane Walder
Michael Walder
Jeanette Wax (FFS)
Joseph Weintraub Family Foundation, Inc.
(Grand Founder)
Eric and Shelley Weis (FFS)
Joel and Sally Weiss (FFS)
Michael Weisser
Warren and Jill Weisser (FFS)
Maria L. Wiebelt
William Hutton Associates, Inc. (FFS)
Kenneth J. Wolf
Allan and Barbara Wolk
W. P. Productions, Inc.
Allan and Ray Ellen Yarkin (FFS)
Richard and Janet Yulman (Founder)
Z Management Services, Inc.
Joseph Zappala
Paul Zarcadoolas (Grand FFS)
Robert Zuckerman (FFS)
$500 -$999
Advertising Direct Marketing
Consultants of America Inc.
Ronald and Eleanor Ager
Barbara T. Alexander
Andrew Alpert
Michael and Randi Applebaum (FFS)
Bernard Shapiro Fund Inc.
Thomas and Karen Bezold (FFS)
Big Pine Key Lions Club
Jason Binn
Stephen and Jill Bloch
Donald and Geraldine Bohning
Ronald Book
Richard L. Braunstein
Michael and Corina Browarnik
Scott and Jodi Brown (FFS)
Robert J. and Evelyn Carbonell
Centex Homes
Beryl L. Cesarano
William and Dolores Chambreau
Robert and Azucena Cherry
City Photo, Inc
Edmond Gong and Dana L. Clay
Comerica Bank
Harold and Alice Commings
Corina Enterprises, Inc.
Cox Enterprises, Inc.
Crispin Porter Bogusky
Wayne and Nicole Cypen
Brian Davidoff
Jean and Tallie Davis
Deloitte & Touche
Destination Resort Management, Inc.
John and Marianne Devine (FFS)
Dimensional Plastics Corporation
Ethel Blum Dublin
Eagle Brands, Inc.
Seymour and Marsha Edelman
Aaron and Andrea Edelstein
Barry Ehrenfeld
Eli J. Ehrlich
Carol A. Eisenberg
Stewart Eisenberg
Lisa Enfield
Jose and Lilia Fernandez
Richard Finkelstein
Adrian Fogel
Lori J. Fogel
Lloyd and Dolores Foley
Stephen E. and Nancy Frank (FFS)
10
28
Fri-Mar Activewear & Shoes, Inc.
Allen and Susan Fuller
Evelyn Gargano
Michael Gates
Gateway Investment Advisers
Henry and Ilene Gayer (FFS)
Martin and Gladys Gelb
James A. Gillis
Daniel and Nancy Ginsberg
Allan M. and Patty Glaser
Peter S. Gold
Michael C. and Cathy Goldberg (FFS)
Patricia Goldsmith
Gloria Gottlieb
Gene and Pauline Grabarnick
Greek Orthodox Ladies Philoptochos
Society of St. Catherine
Victor and Maralyn Green
David and Andrea Grossman (FFS)
Sheldon B. Guren
Merrick W Hellyar
Alan Hodes
Lynn Hover
Juliano H. Ibarra
Jerry and Barbara Isan (FFS)
Michael and Laura Jones
Albert and Arlene Kahn
Edythe Kay
Perry and Annamae Kaye
Roy and Caryl Barrie Kaplan
Steven R. and Nancy Kaplan
Kaufman Foundation, Inc.
James Kennedy
Alfred and Jane Ketcham
Kiwanis Club of Deerfield Beach
Ronald M. and Carol Kovnot
Donald and Eileen Kramer
Brad Krassner
Stanley J. Krieger
Richard and Margaret Kronenberg
Roni and Joanne Laskin (FFS)
Michael and Alexa Lazarus
Marvin H. and Isabel Leibowitz
Lennar Corporate Center &
The Patronis Group
Mike and Phyllis Levin
Stanton and Sandra Levin
Laurence Levy
Alvin F. and Helen Lindsay
Michael A. and Andrea Love
Josie Manno
Jeffrey and Barbara Martin
Mechanix Wear Renthal America
Medical Faculty Association of the
University of Miami
Hillel and Judith Meyers
Jerry Milgram
David Miller
Harold S. Miller
Kevin Fitzmaurice and Renu Mody (FFS)
Ronald Molko
Anthony R. and Beth Morgenthau
Kelli Morris
N. A. Crane
Winston F. and Ruby Nees
Joseph Nesbitt
Stuart G. and Sandy Newman (Founder)
Jim and Heidi Nosich
Harvey Oxenberg
Oxford Services, Inc.
Hermine Pallot
Eugene and Althea I. Peck
Q U EST
PEICO
Corali Pino
Jason H. Port
Profit Concepts
Q. Grady Minor & Associates, P.A.
Mary Belle Quesenberry
Jack Carmel and Katika Quittner
(Founder)
Joel and Sandra Rattner
Steven Rindley
Morton J. and Jane Robinson
Juan M. Rodriguez
Joann Rosen
Robert and Jill Rosenhaus
Ruden McClosky Smith Schuster &
Russell, P.A.
Steven Sanders
David and Marli Sandri
David and Carrie Schulman
Deborah K. Schwarzberg
Peter H. and Miriam Segall
Ginny Sembello
Howard and Frances Shapiro
Steven and Ellen Shapiro
Jean Scheinman
Jeffrey G. Schwarz
Craig B. and Ellen Sherman (FFS)
Michael and Barbara Sherman (Founder)
G. Robert and Joni Sheetz (FFS)
Michael S. Smith
Carol Soffer
F. Ronald and Alexandra Mastriana-Solal
(FFS)
Somerstein Land Co.
Richard N. and Carol Songer
South Florida Trane
Robert and Arlene Spevak
Adam and Jill Spring
David Stone
Robert and Michele Stone
Pat Strawgate
Norman Strell
John and Blair Strickroot
Mathew and Linda Swalling
J. Kenneth and Sandy Tate
Francisco Tejada
Jim Teper
John W. Thatcher
The Cartledge Foundation Inc.
The Comras Company of Florida, Inc.
The Dadeland Capri Apartments
The Efron Foundation, Inc
The Gloria and Sidney Danziger
Foundation, Inc.
The Hasey Foundation
Tom Thumb Food Stores, Inc.
University of Miami
Philip J. and Sandra Walsh
L. Austin and Marta Weeks
William Morse
David S. Wilson
Julieana Wilson
Pauline Winick
Larry F. Witte
David and Shelley Wolfberg
Allan and Barbara Wolk
Teri Esther Wolofsky
Louis and Lillian Yagoda
Antoinette Zel
Richard and Susan Zinn (FFS)
Richard Zipes
Matthew Zucker
$250 - $499
AD Hoc Law Associates, Inc.
Harvey B. Adelstein
Alexander Lynn & Associates
Barry R. and Franne Alter
Beatrice Arnel
Jose and Lourdes Arriola (Founder)
ASL Enterprises, Inc.
Robert and Jo Ann Bass
Betty Bellman
Pedro F. and Barbara Bermann
Kenneth and Marla Bern
Todd and Diana Berwick
Karl and Carmen Bishopric
Bluestein and Wayne, P.A.
B. Pila Design Studio
Robert W Baird & Co. Foundation, Inc.
BRESTL, Inc
Elmer L. Bunge
Barbara Burnstine
Juan and Elda Cabrera
CAM Associates
Heloisa Campos
Capital Rental Agency, Inc.
Angel Castro
Causeway Lumber Company
Honorable Paul and Trudy Cejas
(Founder)
Kenneth and Merryl Chaitman
Maria E. Chance
Afif and Mona Chanouha
Katherine A. Chouinard
Terri Clark
Dan and Patricia Cohen
Jay Cohen
Leonard and Brandy Cohen
Nicholas Condorousis
Richard Conway
Steven and Susan Dandes
Betty Y. Dean
Perry and Geraldine Delman
Victor Demetrion
Nancy Donner
Dennis Doucette
Neil Eisenberg
Lawrence and Carole Epstein
Mark and Paula Epstein
F. Mary Fee
Michael and Nancy Feldman
Michael Fichtel
John W. and Iris Fisher
Audrey Frankel
Joseph and Joan Frechette
Ann Fried
Kathy S. Friedman
Joseph Furfaro
Solomon and Esther Garazi
Fredeswinda Garcia
Raymond L. and Jacque Gellein
Terry Glasser
Deborah S. Gold
Sharon Goldman
Charles J Goodell
Ben and Gladys Goulding
John and Doris Greaner
Randolph and Anne Green
Greater Houston Community Foundation
James Griffin
Wayne A. Haltiwanger
John R. Hart, Jr.
William Craig Hayes, III
*deceased
TH E M A G AZIN E O F TH E U N IVER SITY O F MIA MI SYL VES TER C O MPR EH EN SIV E CA N CER CE N TER
MAKING A DIFFERENCE
Manuel and Nyria Herran
Barry and Cynthia Hersh
Arthur H. Hertz
Lawrence C. and Jacqueline Hoff
Hometown Lending Group
Hubert and Carolyn Hine
Morton Howard
Sherrill and MaryAnn Hudson
Lavette Hunter
I J Feldman Foundation
In Source, Inc.
Interamerican Bank
Investec, Ernst & Company
Issa Homes, Inc.
Gilbert Jacobs
Michael Kahn
Abbey Kaplan (FFS)
Alice M. Kaye
Jeffrey B. Kaye
Seymour Keith
Ken Brahms Agency, Inc.
Michael and Kimberley Kraft
Lester and Anna Kreider
J & D Financial Corp.
Joe’s Stone Crab Restaurant
Everett A. Jones
Nelson and Tillie Lancione
Marshall and Joy Landy
Sidney and Ruth Lapidus
Levi, Cahlin & Co.
Sidney Levin
Steven Dan and Sandra Lewis
Jerry and Elena Lindzon
Robert Lopinto
Bernard L. and Meryle Loring
Donna S. Lundy
Lee Mandell
Joel and Elaine Margolies
Thomas and Angela Marroccoli
Joseph Maya
Susan Miller
Carleton and Ruth Mitchell
Garen and Jan Minkler
MK Real Estate Group INC
Beatriz Montanez
Klara P. Mora
Stanley J. and H. Moss
Daniel and Denise Movens
Myra P. and Company, Inc.
Mary V. Nash
National Provisions, Inc.
Lucas C Nordejee
Francisco J. and Elizabeth Olazabal
Lawrence E. Major and
Suzanne Pallot (FFS)
Ana Paredes
Dennis J. Patin
Ana M Peña
Armando A. Perez
Albert Hernandez and Aymee Perez
Ora F. Phillips
Pipe Vine, Inc.
Anolan Ponce
Juan and Carmen Prieto
Peter and Barbara Pruitt
Stanley K. Reiss
Ana Maria Reyes
Richard Cheroff Sales, Inc.
RMW
Debbie Robins
Edward Robinson
Alejandro and Elda Robles
Frank L. Rosenblatt
Howard H. and Elaine Roth
Neal and Vicki Roth
Sondra Fleck Rubin
Gina Russ
Jon A. and Jayne Sale
Richard Schaeffer
Audrey Schanfald
Carol Schiller
Melvin D. and Gladys Schiller
Alejandro R. Scopelli
Stanley and Harriet Seren
Gary and Dana L. Shear (FFS)
Gary and Tina Silverstein
Charles and Sandra Simon
Kay Sirianni
Eileen Solimene
Carmi M. Slomovitz
Starwood Vacation Ownership SVO-Legal
Dept.
Michael and Joan Storch
Cynthia Swol
Tanenbaum Harber of Florida
The Zurich U.S. Foundation
Barbara Tifford
Titles Unlimited Inc.
Sandro M. Tomaselli
Eden Torres
Robert H. and Jacqueline Traurig
Carrie Ola Trop
Omar and Haydee Vazquez
Irving and Kay Waltman
Water Works of Boca, Inc.
Douglas Weiser
Phyllis Weiss
White & Case
Vincent J. Wing
Zubi Advertising Services, Inc.
DONOR RECOGNITION
SOCIETIES
MERRICK
$1,000,000 and above
ASHE
$500,000-$999,999
IBIS
$250,000-$499,000
GRAND FOUNDER
$100,000-$249,999
FOUNDER
$50,000-$99,999
GRAND FRIEND
$25,000-$49,000
F R IEN D S F O R S Y LV ES TER
(FFS)
Pledge $10,000 over a
maximum of 10 years
(cumulative giving levels)
CIRCLE OF PROMISE
M
embers of the Circle of Promise belong to a select and unique group of individuals, distinguished by their generosity and determination
to eradicate cancer. The Circle of Promise: helping more people in South Florida survive cancer.
Abascal, Maria E.
Adelstein, Harvey B.
Angelo, Jr., Henry
Arnel, Beatrice
Baker, Elaine M.
Baros, Evans E.
Bayer, Cathy
Behar, Saby
Berg, Estelle C.
Birger, Arlyne
Bolz, Charles S.
Brown, Elizabeth
Byrne, Wynn K.
Candib, Murray A.
Carbonell, Robert J.
Carmona, Leticia I.
Castillo, Maria Pessoa Pereira
Chonoles, Jack R
Chouinard, Katherine A.
Christenson, Joyce L.
Clarey, John R.
Clingan, Thomas A.
Cohen, Leonard
Cohen, Myrna
Q U EST
Corrigan, Melita
Creative Pharmacy
Services, Inc.
Cristy, Delia
Crocker, John F.
Dingeldein, Margarete
Epstein, Paula
Esman, Theresa M.
Fennell, Trudy H.
Filloramo, Ida
Fink, Renee
Frechette, Joan G.
Galatz, Arthur
Galperin, Martha Goldman
Glasser, Meredith C.
Gonzalez-Mir, Jaime J.
Goulding, Gladys
Greaner, Doris F.
Green, Anne Wilson
Green, Donald M.
Hagelberg, Beatrice
Herran, Manuel
Hokin, Eugene F.
Hyman, Michael L.
Jackson, Myrtle M.
Jordan, Betsy P.
Kaiser, Gerard A.
Kaplan, Edward S.
Ketcham, Alfred
Kingsberg, David M.
Kramer, Donna R.
Kranitz, Florence
Leitner, Irving
Levin, Sandra
Levy, Marvin
Lindsay, Alvin F.
Longo, Marteen
Lopez, Luis E.
Lopez-Aguiar, Carlos
Lopinto, Robert
Loring, Bernard L.
Lundy, Edith
Milo, Anne M.
Moffat, Ewan C.
Mooers, Malcolm M.
Moses, Edward A.
Movens, Denise
Muroff, Gloria
Nelson, Audrey R.
Nichols, Eleanor M.
Nitenson, Sheldon
Ober, Marjorie Y.
P.A.L. Resources, Inc
Parent Services, Inc.
Peña, Ana M
Purcell, Ania S.
Rabin, George M.
Rebhan, Lori
Rechtman, Lorraine
Retchkiman, Guillermo
Robins, Idah D.
Rodriguez, Eloisa
Rodriguez, Juan M.
Roggenburg, Sanford
Rosen, Muriel
Rosenblatt, Frank L.
Ruiz, Angela G.
Ruiz, Manuel
Sandberg, Deborah D.
Schleifer, Nancy
Schwartz, Jay D.
SECO Supplies, Inc
TH E M A G AZIN E O F TH E U N IVER SITY O F MIA MI SYL VES TER C O MPR EH EN SIV E CA N CER CE N TER
Sendlein, Lyle V.A.
Shochet, Suzanne
Shuminer, Leila K.
Silverstein, Raquel
Simon, Sandra
Stavrojohn, Evonne S.
Stein, Marcia G.
Steinberg, Harris N.
Stern, Donald E.
Stock, Shara L.
The David & Susan Strauss
Foundation, Inc.
Tate Enterprises
Taylor, Charles G.
Thornton, Melinda S.
Vazquez, Haydee C.
Vazquez, Rosa
Wahl, Thomas B.
Waldron, Edward J.
Weinberg, Frances
Weiss, Phyllis
Wiegand, Joseph P.
Yambo, Inc.
Zarcadoolas, Paul
10
29
FACTS AND FIGURES
U M / S Y LV E S T E R I S O N T H E M O V E
A
careful look at our financial and clinical profiles shows that UM/Sylvester is
a financially strong and growing cancer center, and an important source of
research funding throughout the University of Miami School of Medicine.
FINANCIAL PROFILE—HOSPITAL
FY 2001
FY 2002
FY 2003
SOURCES OF REVENUE (Figure 1)
Net patient revenue
Other revenue (operating and non-operating)
$89,884,430
2,278,481
$108,002,717
2,986,515
$108,829,476
2,732,015
TOTAL REVENUE
$92,162,911
$110,989,232
$111,561,491
USES OF REVENUE (Figure 2)
Salaries and related costs
$29,821,556
$32,620,669
$38,102,336
Supplies
16,606,237
19,229,674
20,850,783
Utilities and maintenance
Purchased services
3,350,418
12,877,814
3,366,238
15,889,997
3,741,965
17,673,474
Provisions for bad debt
TOTAL OPERATING EXPENSE
4,841,166
6,436,286
4,416,075
$67,497,191
$77,542,864
$84,784,633
$24,665,720
$33,446,368
$26,776,858
INCOME BEFORE FINANCING COSTS, DEPRECIATION,
AND SUPPORT OF ACADEMIC MISSION
Financing costs and depreciation
Support of academic mission*
$5,901,361
$6,903,344
$7,197,727
$18,764,389
$26,543,024
$19,529,131
*Each year the hospital contributes a portion of its net revenues to support the academic mission (research, teaching, and clinical care) of UM/Sylvester and the University of Miami
School of Medicine.
FINANCIAL PROFILE—RESEARCH
FY 2001
FY 2002
FY 2003
SOURCES OF REVENUE (Figure 3)
Institutional support
Hospital
$600,000
$1,125,313
$1,125,313
School of Medicine
State of Florida
252,287
2,500,000
241,632
2,000,004
1,234,030
1,875,192
$3,352,287
$3,366,949
$4,234,535
$6,010,421
25,314,065
$5,536,540
28,345,095
$7,279,347
30,775,619
$34,676,773
$37,248,584
$42,289,501
$31,484,772
$34,765,859
$38,652,635
1,424,188
1,022,916
1,456,549
1,767,813
$34,676,773
1,459,809
$37,248,584
2,180,317
$42,289,501
Total Institutional Support
Philanthropy* (Figure 5)
Cancer-related sponsored program funding
TOTAL REVENUE
USE S OF RE SEARCH FUN DIN G (Fi g ure 4)
Investigator/research programs
Research resources
Infrastructure
TOTAL RESEARCH FUNDING
*With the exception of sponsored program funding in the form of grants, UM/Sylvester relies most heavily on philanthropic support to fund cutting-edge basic and translational research.
F I N A N C I A L P R O F I L E — U M / S Y LV E S T E R
Total revenue—hospital
Total revenue—research
TOTAL REVENUE (Figure 6)
10
30
Q U EST
FY 2001
FY 2002
FY 2003
$92,162,911
$110,989,232
$111,561,491
34,676,773
37,248,584
42,289,501
$126,839,684
$148,237,816
$153,850,992
TH E M A G AZIN E O F TH E U N IVER SITY O F MIA MI SYL VES TER C O MPR EH EN SIV E CA N CER CE N TER
FACTS AND FIGURES
S O U R C E S O F R E V E N U E — H O S P I TA L
U S E S O F R E V E N U E — H O S P I TA L
FIGURE 1
FY 2003
FIGURE 2
FY 2003
$2,732,015
17.5%
34.2%
6.5%
4%
$108,829,476
15.8%
3.4%
Salaries and related costs
Supplies
Utilities and maintenance
Purchased services
Net patient revenue
Other revenue (operating and non-operating)
SOURCES OF REVENUE— RESEARCH
18.7%
Provisions for bad debt
Financing costs and depreciation
Support of academic mission
USES OF REVENUE—RESEARCH
FIGURE 3
FY 2003
FIGURE 4
$1,125,313 $1,234,030
$1,875,192
FY 2003
3.4%
5.2%
$7,279,347
Hospital
School of Medicine
State of Florida
Philanthropy
Cancer-related sponsored program funding
91.4%
$30,775,619
Research resources
Infrastructure
Investigator/research programs
PHILANTHROPY
T O TA L R E V E N U E —U M / S Y LV E S T E R
FIGURE 5
FY 2001-2003
FIGURE 6
FY 2001-2003
$7,279,347
$6,010,421
$5,536,540
2001
Q U EST
2002
2003
2001
Total revenue—research
Total revenue—hospital
TH E M A G AZIN E O F TH E U N IVER SITY O F MIA MI SYL VES TER C O MPR EH EN SIV E CA N CER CE N TER
2002
2003
10
31
FACTS AND FIGURES
C L I N I C A L P R O F I L E — H O S P I TA L
FY 2001
Inpatient beds
Surgery suites
FY 2002
FY 2003
40
4
40
4
40
4
2,345
1,922
4,267
2,696
2,410
5,106
2,877
2,491
5,368
Clinical trials underway**
Therapeutic
Non-therapeutic
Total
125
36
161
115
37
152
86
40
126
Clinical trial accruals
Therapeutic
Non-therapeutic
Total
210
122
332
305
278
583
257
261
518
Inpatient admissions (Figure 8)
1,040
1,017
1,114
Hospital days
Inpatient
Observation
Total
7,192
2,775
9,967
7,293
3,075
10,368
7,484
2,816
10,300
27.3
6.9
169,487
2,592
10,147
4,085
28.4
7.2
175,792
2,793
10,848
3,992
28
7.0
174,210
2,794
9,858
4,445
47%
24%
13%
6%
10%
46%
23%
15%
6%
9%
45%
25%
16%
5%
9%
Patient volume* (Figure 7)
New cancer patients treated at UM Hospital and Clinics
New cancer patients supervised by UM faculty at Jackson Memorial Hospital
Total
Average daily census
Average length of stay
Outpatient visits (Figure 9)
Surgical cases (Figure 10)
Patients receiving chemotherapy
Patients receiving radiation therapy
Patient base demographics
% from Miami-Dade
% from Broward
% from Palm Beach
% International
% Other
*Patient volume as reported to the State of Florida; data are one year behind.
**During FY 2003, all clinical trials were carefully reviewed. Those that did not meet stringent standards for scientific merit and those that were not accruing subjects in a timely
fashion were closed.
N E W PAT I E N T V O L U M E
I N P AT I E N T A D M I S S I O N S — H O S P I TA L
FIGURE 7
FY 2001-2003
FIGURE 8
FY 2001-2003
(As reported to State of Florida; data are one year behind)
1,114
1,040
2001
2002
2003
New cancer patients supervised by UM faculty at Jackson Memorial Hospital
New cancer patients treated at UM Hospital and Clinics
O U T PAT I E N T V I S I T S — H O S P I TA L
FIGURE 9
2001
1,017
2002
2003
S U R G I C A L C A S E S — H O S P I TA L
FY 2001-2003
FIGURE 10
FY 2001-2003
175,792
2,793
2,794
2002
2003
174,210
2,592
169,487
2001
10
32
2002
Q U EST
2003
2001
TH E M A G AZIN E O F TH E U N IVER SITY O F MIA MI SYL VES TER C O MPR EH EN SIV E CA N CER CE N TER
UM/SYLVESTER LAUNCHES NEW WEB SITE
W
e have some exciting news! Later this year we will be launching our new
web site at www. sylvester.org. We are very proud of our efforts to make
this site informative and easy to read and understand. On the UM/Sylvester site you
will have a chance to meet some of the “names and faces” that work with us every
day, and learn how you can help in our search for a cure. Please check in from time
to time so that you’re “first in line” for the launch.
QUEST
Editor
Felicia Lopez-Walker, M.S.B.
Design
Sabia Communications Inc.
Photography
Steve Gold, Donna Victor, and
UM School of Medicine Biomedical
Communications
On the Cover
The Sylvester Family
Direct inquiries to:
Published by the Office of Marketing and
UM/Sylvester Marketing and
Communications for patients, donors, and
Communications
friends of the University of Miami
1475 N.W. 12th Avenue, Suite C002
Sylvester Comprehensive Cancer Center.
Miami, Florida 33136
All contents ©2003, University of Miami.
Telephone: 305-243-4302
Contents may be reproduced by
Fax: 305-243-4146
permission from the editor and if
E-mail: flopez1@miami.edu
appropriate credit is given.
P AT I E N T P R I V A C Y P R O T E C T E D
Of the many types of personal information, health information is among the most sensitive. The Health Insurance Portability and Accountability Act of 1996 (known as HIPAA)
is federal legislation that protects the privacy and security of patients’ health information (referred to as PHI). The new privacy rules, which took effect April 14, 2003, assure
that patient’s sensitive health information will be kept confidential.
The University of Miami Sylvester Comprehensive Cancer Center is committed to protecting the information of its patients. A central privacy office has been established to
facilitate all patient rights requests and promote a culture of privacy at UM/Sylvester.
The privacy office can be reached at 305-243-5000 or by email at privacy@miami.edu.
With these measures in place, patients can be confident that their privacy and confidentiality will be protected.
If you do not wish to receive Quest in the future, please send your request in writing
to the University of Miami Privacy Office, P.O. Box 019132 (M-379), Miami, Florida 33101.
Q U EST
TH E M A G AZIN E O F TH E U N IVER SITY O F MIA MI SYL VES TER C O MPR EH EN SIV E CA N CER CE N TER
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