2015_Notebook - The Massachusetts Technology Transfer Center
Transcription
2015_Notebook - The Massachusetts Technology Transfer Center
June 2, 2015 Welcome to Massachusetts Life Sciences Innovation Day! Once again, it is our pleasure to bring together major organizations throughout the state to create a high-energy, hands-on event which includes scientific leaders and business experts to mingle with innovators, post-docs, professors, entrepreneurs, and venture capitalists. This is the biggest day for life sciences startups and innovation in the Commonwealth of Massachusetts. This year’s theme is “Weathering Healthcare Climate Change.” Our speakers and panelists will consider how the environment, in which new inventions are commercialized and start-ups are created, is constantly and radically changing; and how do you make sure that your commercialization plan is robust enough to weather all of the changes that may impact your plan. Our speakers and panelists have years of experience and represent a wide range of technologies and inventions – they will talk about how they have survived past changes and hope to live through future ones. They are presidents, CEOs, investors and consultants of leading companies and institutions throughout the area. We hope you find their discussions thought provoking. The Poster Competition includes some of the greatest and newest ideas that could impact medicine in the future. Remember to invest your “MALSI dollars” in your favorite posters – it could help the inventors raise their first round of investment! Winners will be announced by State Senator Karen Spilka during our ever popular evening reception. The reception will also be attended by many additional life sciences CEOs who will join us late afternoon to help judge the poster finalists. Don’t miss the opportunity to speak with them and discuss your projects. We are particularly grateful to our Planning Committee for their help, support and entrepreneurial spirit in organizing this event. We would also like to thank all of our sponsors, particularly Pepper Hamilton LLP and the Massachusetts Life Sciences Center, our lead sponsors for this event. All of our sponsors are as committed as we are to supporting the creation of new companies and we are grateful to them all. We hope you enjoy our flagship event of life sciences in Massachusetts, jointly and actively put together by all the major organizations that are involved in starting and supporting the life sciences start-up ecosystem in the Commonwealth. Dr. Abigail A. Barrow Chair MALSI Director, MTTC Interim Executive Director, OTCV-UMass 8th Annual Massachusetts Life Sciences Innovation Day Table of Contents Floor Plan – Harvard Club of Boston................................................................................................iii Conference Agenda ..............................................................................................................................iv Speaker Biographies...............................................................................................................................6 MALSI Day Planning Committee.................................................................................................... 23 Sponsors, Affiliates & Organizers.................................................................................................... 25 Gold Sponsors.................................................................................................................................................................26 Silver Sponsors................................................................................................................................................................28 Conference Supporters................................................................................................................................................30 Organizers.........................................................................................................................................................................31 In association with ........................................................................................................................................................34 Poster Presenters.................................................................................................................................. 35 Innovators’ Marketplace Exhibitors................................................................................................ 42 Life Science Products and Services .........................................................................................................................42 Entrepreneurship Support..........................................................................................................................................42 Funding..............................................................................................................................................................................43 Professional Services.....................................................................................................................................................43 ii Floor Plan – Harvard Club of Boston TIME SESSION Foyer Harvard Hall Registration & Breakfast 8:00 AM Harvard Hall 9:00 AM Welcome by Conference Chair Abigail Barrow, Director, Massachusetts Technology Transfer Center and by Massachusetts Life Science Center 9:10 AM Opening Keynote Mason (Skip) Irving III, Vice President, Stemnion, Inc, author of Impact 2020 9:40AM Plenary Panel: Startups that got funded in the last 18 months Panelists: Patrick Anquetil, CEO & Co-Founder, Portal Instruments Inc. Marcia Fournier, Founder & CEO, BIOARRAY Therapeutics Inc. Geraldine Hamilton, President & CSO, Emulate Ruben Salinas, President & CEO of Parsagen Diagnostics Moderator: Thomas Engellenner, Partner, Pepper Hamilton LLP Harvard Foyer and Commonwealth Lounge on the 1st Floor 10:30AM 11:00 AM NETWORKING BREAK / POSTER & STARTUP SHOWCASE Massachusetts Room Estabrooks Room The Nuts and Bolts of what to do after you have cashed your first investor check If you build it will they come? Creating a compelling value proposition for your idea Panelists: Panelists: Jeff Behrens, President & CEO, Siamab Therapeutics, Inc. Richard Berenson, CEO, Thermalin Diabetes Will Cowen, Managing Partner, Long River Ventures Eric Walters, CEO, Co-Founder & Director, ONEighty C Technologies Corporation Carl Berke, Partner, Partners HealthCare Innovation Fund Prem Das, Chief Research Business Development Officer, Belfer Office for Dana-Farber Innovations Aaron Sandoski, Co-founder & Managing Director, Norwich Ventures Josh Tolkoff, Partner, Ironwood Equity Moderator: Scott Samuels, Partner, Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C. Moderator: Richard Anders, Founder & Managing Director, Mass Medical Angels Harvard Hall 12:15 PM Remarks by Katie Stebbins, Assistant Secretary of Innovation, Technology, and Entrepreneurship, Massachusetts’ Executive Office of Housing and Economic Development Lunch Keynote Roger Tung, Co-Founder, President & CEO, Concert Pharmaceuticals 1:45 PM Massachusetts Room Estabrooks Room Early risk reduction of your technology in the lab Health policy and how its changing will shape the life sciences sector Panelists: Bill Edelman, Chairman of the Board, Vitathreads LLC Curtis Keith, CSO, Blavatnik Biomedical Accelerator at Harvard University Mark Ralph, Director, External Partnership Operations, Boehringer Ingelheim Kevin Scanlon, Founder & CEO, International BioScience Panelists: Jonathan Fleming, Managing Partner, Oxford Bioscience Partners Michael Greeley, General Partner, Flare Capital Partners Laura Housman, Senior Vice President, Molecular Health Moderator: Moderator: Seth Taylor, CFO & CBO, Mass Innovation Labs Edward Berger, Principal & Founder, Larchmont Strategic Advisors Harvard Foyer and Commonwealth Lounge on the 1st Floor 3:00PM 3:30PM NETWORKING BREAK / POSTER & STARTUP SHOWCASE Massachusetts Room Estabrooks Room Start-up lessons learned...the hard way First financing for emerging companies Panelists: Panelists: Denise Aronson, President & Founder, Safety Partners Jeff Arnold, President, Arnold Strategies, LLC Paulina Hill, Principal, Polaris Partners Roger Kitterman, Executive Director, Boston Biomedical Innovation Center Darshana Zaveri, Partner, Catalyst Health Ventures Pravin Chaturvedi, Founder & Chairman, IndUS Pharmaceuticals Thomas Forest Farb, President, Thrive Bioscience, Inc. John Tagliamonte, Chief Business Officer, Oxyrane Moderator: Roger Frechette, Partner & Co-founder, New England PharmAssociates Moderator: Imran Nasrullah, Director, Innovation Sourcing, Boehringer Ingelheim Harvard Hall 5:00 PM Reception / Innovators’ Marketplace Poster Awards by Karen Spilka, State Senator, 2nd Middlesex and Norfolk district 8th Annual Massachusetts Life Sciences Innovation Day Speaker Biographies Richard Anders.........................................................................................................................................7 Patrick Anquetil........................................................................................................................................7 Jeff Arnold..................................................................................................................................................7 Denise Aronson........................................................................................................................................8 Abigail Barrow..........................................................................................................................................8 Richard Berenson.....................................................................................................................................9 Edward Berger....................................................................................................................................... 10 Carl Berke................................................................................................................................................. 10 Pravin Chaturvedi ................................................................................................................................ 11 Will Cowen.............................................................................................................................................. 11 Prem Das ................................................................................................................................................. 12 Bill Edelman ........................................................................................................................................... 12 Tomas Engellenner.............................................................................................................................. 13 Thomas Forest Farb.............................................................................................................................. 13 Jonathan Fleming................................................................................................................................. 14 Roger Frechette .................................................................................................................................... 14 Michael Greeley..................................................................................................................................... 15 Geraldine Hamilton............................................................................................................................. 15 Paulina Hill.............................................................................................................................................. 16 Laura Housman..................................................................................................................................... 16 Mason (Skip) Irving, III......................................................................................................................... 17 Curtis Keith............................................................................................................................................. 17 Roger Kitterman.................................................................................................................................... 18 Imran Nasrullah..................................................................................................................................... 18 Mark Ralph ............................................................................................................................................. 18 Scott Samuels........................................................................................................................................ 19 Aaron Sandoski..................................................................................................................................... 19 Kevin Scanlon........................................................................................................................................ 20 Katie Stebbins........................................................................................................................................ 20 John Tagliamonte ................................................................................................................................ 20 Seth Taylor............................................................................................................................................... 21 Josh Tolkoff............................................................................................................................................. 21 Roger Tung.............................................................................................................................................. 21 Eric Walters ............................................................................................................................................. 22 Darshana Zaveri.................................................................................................................................... 22 6 Biographies June 2, 2015 Harvard Club of Boston Speaker Biographies Richard Anders Founder & Managing Director, Mass Medical Angels Richard Anders is a long-time entrepreneur. He founded the legal software publishing company Jurisoft, which he sold to Lexis/Nexis, published newspapers including Boston Digital Industry and New York Digital Industry and is currently managing director of Rubin/Anders Scientific, which places scientists as consultants in patent projects. He served for many years as a member of the Institutional Review Board at the Dana Farber Cancer Center, and was a long-time trustee of the Museum of Science, where he currently is an overseer. Richard founded and currently runs MA Medical Angels (MA2), one of the country’s leading angel groups focused exclusively on life sciences. He founded the angel group Launchpad, the nationally renowned Science on Screen event at the Coolidge Corner Cinema, and was a founding trustee of the Massachusetts Interactive Media Council. He is a board observer at Avaxia Biologics and Sialix and an overseer at the Gardner Museum. Richard teaches medical device entrepreneurship at the Harvard/MIT HST program. He is a graduate Summa Cum Laude in Mathematics from Harvard and holds a J.D. from Harvard Law School. Patrick Anquetil CEO, Portal Instruments, Inc. Dr. Patrick Anquetil is the CEO at Portal Instruments, where he is leading the company from inception to its first product. Patrick began his career as a science and nanotechnology equity research analyst at Susquehanna International Group. He subsequently co-founded SynapDx Corp. a medical diagnostic company in the field of autism. He received a PhD in Bio-Instrumentation from MIT, an MBA from Harvard Business School and a Master’s degree from the ETH in Zurich and the University of Tokyo. His work has appeared in peer-reviewed publications as well as mainstream media such as MIT Technology Review, Wired Magazine, PBS, and CNBC. Jeff Arnold President, Arnold Strategies, LLC Mr. Arnold is the president of Arnold Strategies, LLC, a strategic advisor to early and growth stage CEO’s, and an angel investor with Mass. Med. Angels and Boston Harbor Angels. As an angel investor, Mr. Arnold, has invested in, among others, SmartCells (sold to Merck), BioAssets development Corp (sold to Cephalon), Syntonix (sold to Biogen Idec), Health Honors (sold to Healthway) and JB Therapeutics (now public as Corbus Pharmaceutical Holdings). Prior to founding Arnold Strategies, Mr. Arnold spent 20 years as the CEO of multiple private and public technology and life science companies. Among these include Cambridge Heart, a cardiology diagnostics company which he founded and took public, CardioFocus, a VC backed catheter ablation company and Accelrys, a public company with software tools for rational drug design, now a division of Dassault Systemes. Mr. Arnold is a guest lecturer at the MIT Sloan School, mentor at the MIT Venture Mentoring Society, on the Grant Review Board of the MIT Deshpande Center and on the Board of Overseers at the Museum of Science. He was formerly Chairman of the Greater Boston Chapter of the American Heart Association. He received a BSEE from MIT in 1972. Biographies 7 8th Annual Massachusetts Life Sciences Innovation Day Denise Aronson President & Founder, Safety Partners, Inc. Denise Aronson is a pioneer in the life science health and safety industry. Denise founded Safety Partners Inc. in 1992. Since then, Denise and her team have implemented safety programs for more than 275 top life science companies. Prior to founding Safety Partners, Denise served as an environmental, health, and safety manager at T Cell Sciences, and managed a clinical prenatal diagnostics laboratory. She began her career as a research associate at Beth Israel Deaconess Hospital in Boston, after receiving a BS in Biochemistry from the University of New Hampshire. Denise is a certified chemical hygiene officer through the National Registry of Certified Chemists. She is active in more than 20 professional societies and trade organizations, and was a founding member of the New Hampshire Bio/Medical Council, Preferred Provider Leads Group; the Tom Vance, Life Sciences Connector Group; and the Cambridge Chamber of Commerce, Life Sciences Leads Group. She is a regular on the industry speaking circuit, a member of the MassBio SEF Working Group, and an American Chemical Society (ACS) Expert. Denise also serves on the Advisory Board for the UMass Lowell Department of Work Environment as well as the Boards of The Bioscience Network and The Waldorf High School of Massachusetts Bay. Safety Partners is a Certified Woman-Owned Business, and has been named one of the 25 Best Small Companies by Working Mother magazine. Abigail Barrow Founding Director, Massachusetts Technology Transfer Center and Conference Co-Chair Dr. Abigail Barrow is the Interim Executive Director, Office of Technology Commercialization and Ventures (OTCV) at the University of Massachusetts. She joined the UMass President’s Office in 2004 as the Founding Director of the Massachusetts Technology Transfer Center (MTTC) which is housed in OTCV. At OTCV she supports the campus technology transfer programs as well as assisting with start-up formation and other systemwide entrepreneurship activities at UMass. She is also responsible for the overall management of the MTTC and the development of its programs. Prior to joining UMass, Dr. Barrow served as managing director of William J. von Liebig Center at the University of California San Diego (UCSD). The von Liebig Center was created in 2001 to support the commercialization of research being performed in the UCSD Jacobs School of Engineering. Dr. Barrow worked in a variety of roles at UCSD CONNECT from 1990 to 2001. At CONNECT, she developed and expanded many of its programs to support early-stage company formation and technology commercialization. The CONNECT program is internationally recognized and has been successfully replicated in many other regions around the world. Dr. Barrow is on the board and is Chair of VentureWell (formerly the National Collegiate Inventors and Innovators Alliance). Dr. Barrow received her Ph.D. from the Science Studies Unit and a B.Sc. in Mechanical Engineering from the University of Edinburgh. 8 Biographies June 2, 2015 Harvard Club of Boston Jeff Behrens President & CEO, Siamab Therapeutics, Inc. Jeff is President and CEO of Siamab, Inc., a biotech company focused on developing therapeutic antibodies targeting glycan targets in cancer. Previously, Jeff served as Senior Director, Business Development and Operations at Edimer Pharmaceuticals and also worked at Alnylam and Biogen Idec. In 2003 Jeff sold his healthcare IT company, The Telluride Group, to mindSHIFT Technologies, a Fidelityfunded rollup. Telluride was an information technology managed services provider (MSP) founded in 1995. Jeff has a Lecturer appointment and currently teaches in the HST PhD program at MIT and Harvard Medical School. Jeff has an MS from the Harvard/MIT Division of Health Sciences and Technology (HST), an MBA from MIT Sloan, and graduated from Harvard College. He lives in Newton, MA. Richard Berenson CEO, Thermalin Diabetes LLC Rick is a serial entrepreneur who has successfully launched and financed multiple life science and other organizations around important new technologies in complex markets. He has been CEO or COO of eleven companies; most recently Thermalin Diabetes, LLC (CEO, biotech) and HeartLander Surgical, Inc. (CEO, medical device). Rick has also led companies in consumer products manufacturing, knowledge management, new media, entertainment industry technology, manufacturing software, healthcare information and services, healthcare market research, diagnostic reference laboratory services, and cancer immunotherapeutics. He has raised or helped raise more than $50M in private and non-dilutive capital. A former McKinsey & Company consultant, Rick received a JD-MBA from Harvard Business and Law Schools in 1984 and is a graduate of Harvard College. Rick began his career at AT&T Bell Laboratories as a member of technical staff where he helped launch internal ventures. He then worked at several software startups in the Boston area before joining McKinsey & Company as a management consultant. Subsequently, Rick has been CEO of ActivBiotics (early stage biotech), Banton Precision Wood Products (consumer products manufacturer), NewSphere (knowledge management software), Student.Com, Inc. (new media), and TVGrid (technology for the entertainment industry). He has also served as COO at ChannelHealth.Com (healthcare information and e-commerce), Morpace Pharma Group (medical market research), and AltiComm (telecom). Rick has advised other companies through Paris-based ALLIANCES Management Consultants, Monadnock Associates, and most recently Venzyme Catalyst, LLC where he is Managing Director. He serves on the boards of SimulConsult (medical diagnosis decision support software), InCytu (cancer immunotherapy), Massachusetts Medical Angels (angel investing group), and The Freedom Trail Foundation. Biographies 9 8th Annual Massachusetts Life Sciences Innovation Day Edward Berger Principal & Founder, Larchmont Strategic Advisors Edward Berger has nearly 30 years experience in health services, medical technology and life sciences reimbursement, strategic planning, regulatory policy and corporate communications. Through his consultancy, Larchmont Strategic Advisors, he helps life sciences companies create and implement integrated strategies to address the obstacles and opportunities they face in their efforts to secure public and private insurer coverage and optimal reimbursement for new or evolving technologies. Focusing on issues that arise at the intersection of public policy, corporate strategy development, and internal and external advocacy, Dr. Berger helps clients to deal effectively with the strategic challenges posed by the rapidly evolving healthcare regulatory and policy environment. His clients have included companies in fields such as mechanical circulatory support, cardiology, orthopedics, neural monitoring and neuromodulation, gastrointestinal surgery, pulmonary medicine, nuclear medicine, diagnostic imaging, clinical laboratory testing, and personalized medicine. Previously, as a member of the senior management teams of Fresenius Medical Care, Thermo Cardiosystems and ABIOMED, Dr. Berger had primary responsibility for the development and implementation of reimbursement strategy and advocacy as well as the broader range of strategically sensitive communications with government agencies, news media and investors. Dr. Berger also serves as President of cardiothoracic device developer Coraux Technologies, LLC and as a Director of Atanse, Inc., an early stage neurosurgical instrument company. He is a member of Mass Medical Angels, a mentor in Boston University’s IGNITE program, and Past President of the Medical Development Group, a 400 member professional association of individuals professionally committed to the medical device and related life sciences business sectors. He has a Bachelor’s Degree in Government from Harvard College, and earned his Ph.D. in Political Science at Boston University, where he was later Assistant Professor of Political Science and Chair of the Urban Affairs and Planning program. Carl Berke Partner, Partners HealthCare Innovation Fund Carl is a Partner at Partners HealthCare Innovation Fund in Boston, investing in new biomedical technologies emerging from Massachusetts General Hospital and Brigham & Womens Hospital. His career has spanned over 25 years in the practice and management of innovation to bring new technologies from lab to market. As a bench scientist and R&D director, he worked at Polaroid Corporation and Hygeia Sciences in the development of photographic and clinical products – he is an inventor on 6 US patents. He served as a Partner at Integral/Analysis Group, a management consultancy focused on innovation and growth strategy. He has been an active private equity investor as a member of Angel Healthcare Investors LLC and is a founding director of Mass Medical Angels LLC. He has served on the boards of Quosa [literature management software], Kasalis [robotics], Annovation [novel anesthetics], Combinent [drug delivery], Sebacia [acne treatment], Infobionic [cardiac monitoring], QPID Health [bioinformatics], LifeImage [diagnostic image sharing], Syntimmune [autoimmune therapy] and the Sudanese Education Fund [philanthropy]. Carl holds an AB degree from Cornell University and received his PhD in Organic Chemistry from the University of California at Berkeley. He also holds an appointment as Lecturer in the Biomedical Enterprise Program in the Harvard-MIT Division of Health Sciences and Technology. 10 Biographies June 2, 2015 Harvard Club of Boston Pravin Chaturvedi Founder & Chairman, IndUS Pharmace Dr. Chaturvedi is the Founder and Chairman of Boston-based IndUS Pharmaceuticals and a co-founder of Florida-based Oceanyx Pharmaceuticals and also serves as the Chief Executive Officer of both these organizations. He also serves as the Chief Scientific Officer of San Francisco-based Napo Pharmaceuticals. Previously he has served as the President and Chief Executive Officer of Boston-based Scion Pharmaceuticals. Dr. Chaturvedi serves on the boards of IndUS, Oceanyx, FuelEd Schools, Cellanyx, PRADAN USA and Sindu Research Laboratories. He has previously served on the Boards of Scion Pharmaceuticals and TiE Boston. He also serves as an advisory board member to TFC Biosciences and Springboard Enterprises and is the Chair of the Research Advisory Council for the Health Sciences Center of West Virginia University. He is an adjunct faculty member at Georgetown Medical School. Over his 25+ year career, Dr. Chaturvedi has participated or led the discovery and/or development activities for several new chemical entities (NCEs), culminating in the successful development and commercialization of several new drugs that are currently marketed by various companies. Prior to his roles at IndUS, Oceanyx, Napo and Scion Pharmaceuticals, Dr. Chaturvedi, spent several years at Vertex Pharmaceuticals as the Head of Lead Evaluation. Prior to Vertex, he was in the preclinical group at Alkermes and he started his R&D career in the Product Development group at Parke-Davis/Warner-Lambert Company (now Pfizer). Dr. Chaturvedi holds a Ph.D. in Pharmaceutical Sciences from West Virginia University and a Bachelor’s in Pharmacy from the University of Bombay. Will Cowen Managing Partner, Long River Ventures Will has extensive experience building early stage companies both as an entrepreneur and as venture investor. Prior to joining Long River Ventures he was a co-founder and CEO of NaviNet with backing from Northbridge, Atlas, and GE Equities. Today NaviNet is a leading healthcare IT firm which streamlines transactions between healthcare payers and over 800,000 healthcare providers. Prior to NaviNet, Will was CEO of venture-backed Pegasus Medical Technologies, an electronic medical records company sold to HBOC/ McKesson (NYSE:MCK). Early in his career Will was a co-founder of a consumer products company, Thermocell, which is today a $500 million dollar division of the Hunter Douglas Company. On the investing side, Will was a Managing Partner of Interface Technologies and Firepond Partners, two early stage healthcare funds. Will serves, or has served, on the board of numerous companies including Convergent Dental, GetWellNetwork, LifeIMAGE, Medical Metrix Systems, MedVentive, Parsagen Diagnostics, Phreesia, Solais, and Verax Biomedical. Will holds a B.A. from the University of Colorado and a M.B.A. from the Massachusetts Institute of Technology. Biographies 11 8th Annual Massachusetts Life Sciences Innovation Day Prem Das Chief Research Business Development Officer, The Belfer Office for Dana-Farber Innovations (BODFI) Prem joined BODFI in 2012. His background includes managing academic technology transfer offices, biotechnology business development, and basic research. Most recently, Prem was involved in creating start-up companies and consulting to biotechnology companies and the NCI. Prior to joining BODFI, he served as Senior Vice President for Technology Alliances at Praecis Pharmaceuticals, where his business development efforts led to the acquisition of the company by Glaxo-Smith Kline in 2007. Before Praecis, from 2003 to 2006, Prem directed the Office of Technology Licensing at Harvard Medical School. From 2000 to 2003 he was Associate Director of the Office of Industrial Affairs at Memorial SloanKettering Cancer Center. Earlier, he worked at Mount Sinai School of Medicine and Cadus Pharmaceuticals, and co-founded Heartland BioTechnologies. During his academic research career, Prem has published in diverse areas of biology. He received his MSc in Chemistry from IIT/Kanpur in India and his PhD in Biological Chemistry from MIT. Bill Edelman Chairman of the Board, Vitathreads LLC Bill Edelman, is a medical device industry executive with over 35 years experience and currently serves as Chairman of the Board for Vitathreads LLC, (aesthetics wound repair) NewVert, Ltd., (spinal implants), Highland Instruments, Inc., (neurostimulation), Paragonix Technologies, Inc., (organ transport systems), Medivalve, Ltd., (percutaneous aortic valve placement), and Cardioflow, Ltd., (embolic protection). CEO for ETView, Ltd., (TASE: ETVW) (airway management). Mr. Edelman also serves as a Board Member for MindChild Medical, Inc., (non-invasive fetal monitoring). Mr Edelman is an Advisor on the Heathcare Board, for Northeast Securities, Inc., Advisor to First Light Bioscienses, Inc. (automated medical diagnostic products), and serves as a member of the Advisory Council for the Department of Biomedical Engineering at Rensselaer Polytechnic Institute. Mr. Edelman previously served as a member of the Screening Committee for Medical Devices for Mass Medical Angels, Chairman of the Board for Flexicath, Ltd., (IV catheterization), PolyTouch, Ltd., acquired by Covidien in 2011 (general surgical instrumentation), Stimatix GI, Ltd., (ostomy products) and Leviticus Cardio, Ltd., (cardiac assist power systems). Previously, Mr Edelman served as President & Chief Executive Officer, TYRX, Inc., a commercial stage venture backed medical device company focused in drug/device implant products for general surgery, electrophysiology and cosmetic surgery. TYRX was acquired by Medtronic, Inc., in 2014. Prior to TYRX, Mr. Edelman held executive level positions at MicroSense International, LLC (bio-sensing), FibraSonics, Inc. (ultrasonic surgical products), NeuroMod, Inc. (neuro-stimulation technologies), St. Jude Medical, Inc., Pfizer, Inc., and Baxter International, Inc. Mr. Edelman graduated with a degree in Biomedical Engineering from Rensselaer Polytechnic Institute. He has been issued 15 U.S. patents and is an applicant on 5 additional pending patent applications. 12 Biographies June 2, 2015 Harvard Club of Boston Tomas Engellenner Partner, Pepper Hamilton LLP Tom Engellenner is a partner in the Intellectual Property Department of Pepper Hamilton LLP, resident in the Boston office. Mr. Engellenner’s practice includes strategic IP advice, preparation of opinions, patent prosecution and litigation. He has particular expertise in the fields of biotechnology, medical devices, diagnostics, drug development and analytical instruments. Mr. Engellenner has more than thirty years of experience in prosecuting and litigating patents and advising clients generally on intellectual property strategies. Thomas Forest Farb President, Thrive Bioscience, Inc. Thomas Forest Farb has three decades of experience as an entrepreneur, investor, senior executive and mentor in early-stage information technology and life science companies in Massachusetts, California, Florida, Puerto Rico and China. As an entrepreneur, Mr. Farb has been directly involved in founding and in raising more than $135 million of angel and venture capital for over ten companies.As an investor, he has been a partner in two venture capital/private equity firms in Boston and China and as Executive Director of the Trust for Science & Technology in San Juan, Puerto Rico. As a senior executive, he has served as President, COO or CFO of numerous companies, including Atherio Information Systems, Indevus Pharmaceuticals, MedicaMetrix and Cytyc.As a mentor, he has been a Mentor for the Founder Institute and a Senior Advisor at the Microsoft Innovation Center, both in San Juan, Puerto Rico. Mr. Farb is currently President of an early stage life sciences company in the Boston area, Thrive Bioscience, Inc., which is building instruments to automate laboratory and therapeutic cell culture and has just raised more than $3.5 million in seed financing. Mr. Farb has been a member of the Board of Directors of numerous companies including several public companies -- Fair Isaac (NYSE: FIC), Redwood Trust (NYSE: RT), HNC Software (NASD: HNCS), Retek Systems (NASD: RETK), and Symon Communications (NASD: MGN). He has been a Trustee or Advisor for numerous non-profit organizations including the Dana Farber Cancer Institute, Asia America Chamber of Commerce, Partners Healthcare, three private schools and two museums. He is also a Founder and Officer of Brahman Industries, a mission driven company developing floating shelters for use in natural disaster. Mr. Farb is a graduate of Harvard University. Biographies 13 8th Annual Massachusetts Life Sciences Innovation Day Jonathan Fleming President, NEHI Jonathan J. Fleming is President of NEHI, a national health care policy think tank. Founded in 2002, NEHI is a nonprofit, non-partisan, evidence-based institute dedicated to identifying innovations that provide solutions to the most pressing issues facing our health care system today. Since 1999, Mr. Fleming has been the Managing Partner of Oxford Bioscience Partners, an international venture capital firm specializing in life science investments based in Boston, Massachusetts. Mr. Fleming has been in the investment business for more than 29 years, starting and financing growth companies in the United States, Europe, Israel and Asia. Prior to joining Oxford Bioscience Partners in 1996, he was a Founding General Partner of MVP Ventures in Boston, MA. He began his investment career with TVM Techno Venture Management in Munich, Germany. Mr. Fleming also co-founded Medica Venture Partners, a venture capital investment firm specializing in early stage health care and biotechnology companies in Israel, and the Korea Seoul Life Science Fund, based in Seoul, Korea. Mr. Fleming is a director of Xencor (NASDAQ: XNCR) and several private early stage life science companies. He is also a director of Leerink Partners, a Boston based investment bank specializing in health care companies. In addition, Mr. Fleming has been a Senior Lecturer at the MIT Sloan School of Management since 2003, where he co-teaches a class on business strategy for life science managers. He is an advisor to the SBIR program of the National Cancer Institute. Mr. Fleming holds a Master’s degree in Public Administration from Princeton University’s Woodrow Wilson School of Public and International Affairs. Roger Frechette Co-Founder & Principal, New England PharmAssociates Dr. Roger Frechette is the Co-Founder and Principal of New England PharmAssociates, a consultancy offering on-demand executive and business advisory services to life sciences enterprises. He is also the US East Coast Ambassador for Medicon Valley Alliance, a life sciences cluster organization based in Copenhagen. Previously, he was a Co-Founder of Frontiera Therapeutics, a startup developing therapeutics for vascular leak. He is a volunteer adviser and mentor with several Boston area biotech incubators and startup mentoring programs. Previously, Dr. Frechette was Co-Founder of MaxThera, an antibacterial drug discovery company. MaxThera was sold in 2010 to Biota Holdings Limited, a Melbourne Australia anti-infectives company. Prior to starting MaxThera, Dr. Frechette was a drug discovery and life-sciences consultant following his role as Project Director at Paratek Pharmaceuticals (Boston). At Paratek he led the team that discovered PTK0796 (currently in Phase III clinical trials) with strategic partner Glaxo-Wellcome, and also led the pre-clinical development program that was carried out with a multinational team of consultants and contractors. Previously, he was Associate Director of Chemistry at RiboGene (Hayward, CA), where he built the chemistry department and managed two drug discovery programs in collaboration with strategic partner Dainippon Pharmaceuticals. He began his career as a medicinal chemist at the R.W. Johnson Pharmaceutical Research Institute (J&J, Raritan, NJ). Dr. Frechette was a Post-Doctoral Fellow at Yale University, earned his PhD in Organic Chemistry from Wesleyan University and his BA in Chemistry from College of the Holy Cross. 14 Biographies June 2, 2015 Harvard Club of Boston Michael Greeley General Partner, Flare Capital Partners Michael currently serves as a General Partner at Flare Capital Partners. Prior to joining Flare, Michael served as founding general partner of Flybridge Capital Partners where he led the firm’s healthcare investments. He also served on the board of International Data Group, the initial flagship Limited Partner for the IDG Ventures global network of funds and Flybridge Capital Partners. Current and prior board seats include BlueTarp Financial, Explorys, Functional Neuromodulation, Iora Health, MicroCHIPS, Nuvesse, PolyRemedy, Predictive Biosciences, Predilytics, T2 Biosystems, TARIS Biomedical and VidSys. Previously, Michael focused on emerging-growth company financings with Polaris Venture Partners, was a senior vice president and founding partner of GCC Investments, and held positions at Wasserstein Perella & Co., Morgan Stanley & Co. and Credit Suisse First Boston. Michael currently serves as chairman of the Entrepreneurship Committee of the Massachusetts Information Collaborative and on the Investment Committee for the Partners Innovation Fund and Massachusetts Eye & Ear Infirmary. Michael also serves on the Industry Advisory Board of the Cleveland Clinic, as well as serving on several other boards including the New England Investors’ Committee of Capital Innovation. He was the former chairman of the New England Venture Capital Association and on the Executive Committee of the board of the National Venture Capital Association. Named by the Boston Globe as the “Go-To” investor for life sciences, healthcare and medical devices and a Mass High Tech All-Star, Michael earned a B.A. with honors in chemistry from Williams College and an M.B.A. from Harvard Business School. Geraldine Hamilton President & CSO, Emulate Dr. Hamilton’s career spans academic research, large Pharma, and biotech start-ups, with over 10 years’ experience in the pharmaceutical industry. In all three arenas, Dr. Hamilton’s work has focused on the development of new human-relevant cell-based models and their application to drug discovery. This pursuit brought Dr. Hamilton to Harvard’s Wyss Institute, where as a Lead Senior Staff Scientist she directed the extensive Organs-on-Chips project. This project was successfully spun-out from the Wyss Institute to form Emulate, Inc., where Dr. Hamilton now serves as President and Chief Scientific Officer. At Emulate, Dr. Hamilton continues her work to further develop Organs-on-Chips technology as well as to drive and facilitate its adoption in commercial use. Prior to joining the Wyss Institute and Emulate, Dr. Hamilton was one of the founding scientists of the biotech start-up CellzDirect, where she was the VP of Scientific Operations and Director of Cell Products. CellzDirect successfully translated and commercialized technology from academic research to supply the pharmaceutical industry with hepatic cell products and services for safety assessment and drug-metabolism studies. Hamilton received her Ph.D. in cell biology/toxicology from the University of Hertfordshire (England) in conjunction with GlaxoSmithKline, followed by a post-doctoral research fellowship at the University of North Carolina. She has led in vitro toxicology and drug metabolism teams in GlaxoSmithKline and AstraZeneca. Her current research interests and scientific experience include: bioinspired engineering, toxicology and drug metabolism, liver cell biology, mechanisms regulating gene expression and differentiation, regulation of nuclear receptors and transcriptional activation in hepatocytes by xenobiotics, human cell isolation and cryopreservation techniques. Biographies 15 8th Annual Massachusetts Life Sciences Innovation Day Paulina Hill Principal, Polaris Partners Paulina Hill is a Principal at Polaris Partners. Paulina joined Polaris in 2011 and focuses on investments in healthcare. Paulina serves on the boards of Arsenal Medical, Faraday Pharmaceuticals and KinDex Pharmaceuticals and is an observer on the boards of MicroCHIPS and 480 Biomedical. Paulina also works closely with Arsia Therapeutics, an early-stage Bob Langer-founded startup which she was actively involved in spinning out of MIT. Paulina serves on the board of The Capital Network, a non-profit that provides fundraising education to startup entrepreneurs and is part of the Lead Mentor team for Canadian Entrepreneurs in New England. Prior to joining Polaris, Paulina completed her postdoctoral fellowship in the Chemical Engineering department at the Massachusetts Institute of Technology. In the laboratory of Bob Langer, Paulina worked on developing novel biomaterial scaffolds and drug delivery systems for neural applications. Paulina is the founding president of the MIT Postdoctoral Association, and served on the MIT Intellectual Property Presidential Committee. Paulina completed her PhD in Molecular Medicine with a Tissue Engineering focus at Wake Forest University School of Medicine. Her graduate school work resulted in over 40 published abstracts, awards and peer reviewed manuscripts. Her research contributed to numerous patents and the formation of the startup KeraNetics to commercialize the platform technology. Paulina graduated magna cum laude from East Carolina University with a quadruple major in biochemistry, neuroscience, biology and chemistry. She attended East Carolina on an athletic scholarship where she was captain of the women’s tennis team. Laura Housman Senior Vice President, Molecular Health Ms. Housman joined Molecular Health in October 2013 as Senior Vice President, Chief Commercial Officer. In that role, Ms. Housman was responsible for the commercialization of Molecular Health’s suite of treatment decision support tools for enhanced oncology clinical care, successfully launching its first product, TreatmentMAP. Beginning April 2015, Ms. Housman now has responsibility for developing the strategic plan and commercializing intellectual property associated with a novel erythropoietin receptor discovered by Molecular Health’s computational software platform, Nucleus, as Senior Vice President, Corporate Development. By using advanced proprietary information technologies to sift through terabytes of genetic and molecular test findings in a fraction of the time needed for current manual analysis, MolecularHealth provides doctors and patients with faster, more accurate insights into the role genes play in the progression and treatment of an individual’s cancer. Ms. Housman holds a Master of Business Administration with honors from Boston University Graduate School of Management, a Master of Public Health with specialization in Health Services from Boston University School of Public Health, and a Bachelor of Arts degree in Economics with a minor in Business Administration from Boston University College of Arts and Sciences. Additionally, Ms. Housman is on the Faculty of Tufts School of Medicine in Boston, Massachusetts. Ms. Housman is based in the Cambridge Massachusetts U.S. business office for Molecular Health, with global headquarters in Heidelberg, Germany and a CLIA/CAP laboratory in The Woodlands, Texas. 16 Biographies June 2, 2015 Harvard Club of Boston Mason (Skip) Irving, III Vice President, Stemnion, Inc For over 30 years Skip has been advising companies on business strategy, product commercialization, R&D planning and business development in the biotech, pharmaceutical and medical products industries. Skip now serves as Vice President for Stemnion, Inc., a Pittsburgh-based biotechnology company developing novel biologic products for tissue healing. Until recently Skip was a Managing Director at Health Advances. Joining in 1997, Skip helped create a leading life-science focused management consulting firm with over 100 professional staff. Skip’s practice included Fortune 500 companies, venture-backed start-up companies and not-for-profit disease foundations and leading academic centers. Prior to joining Health Advances, as Vice President for Commercial Development at the Massachusetts Biotechnology Research Institute (MBRI), Skip was involved in the founding of seven life sciences companies and created a unique technology licensing office representing eight academic research institutions and over $200 million in research. He helped found and served on the Board of t-Breeders, a cellular therapy company eventually purchased by Perkin Elmer. Prior to MBRI, Skip was Vice President and Director of Worldwide Healthcare Consulting at Arthur D. Little, Inc. where his professional work involved technology planning, R&D management, and strategic alliances. Skip also worked in manufacturing and quality assurance for the sterile parenteral business at AstraZeneca . Skip is a frequent speaker at industry conferences including the Biotechnology Industry Organization and the Licensing Executives Society. He serves on the Board of the Michael J. Fox Foundation for Parkinson’s Research and the Industry Advisory Committee for the Brain Tumor Society. He is also a member of the College Corporation at the Massachusetts College of Pharmacy and Health Sciences where he earned his BS in Pharmacy and serves on the Board of Overseers for Mount Auburn Hospital. Skip earned his MBA at the Amos Tuck School at Dartmouth College. Curtis Keith CSO, Blavatnik Biomedical Accelerator at Harvard University Dr. Keith is Chief Scientific Officer of the Blavatnik Biomedical Accelerator at Harvard University, an innovative program bridging the gap between early-stage life science research at Harvard and successful development of high-impact biomedical products. Prior to joining Harvard University in 2008, Dr. Keith was Senior Vice President of Research at CombinatoRx, a Massachusetts-based biotechnology company which he cofounded in 2000. Under his leadership, CombinatoRx created an integrated technology platform for the discovery of multi-target therapeutics, yielding a broad pipeline of preclinical and clinical drug candidates in areas including rheumatoid arthritis, psoriasis and neurodegenerative disease. Dr. Keith earned his B.Sc. in biochemistry from McGill University and received his Ph.D. in chemistry and chemical biology from Harvard University. Biographies 17 8th Annual Massachusetts Life Sciences Innovation Day Roger Kitterman Executive Director, Boston Biomedical Innovation Center Roger is an experienced venture capital investor with more than 20 years in the industry and has guided multiple venture-backed companies through the earliest stages of development. He has also been the startup CEO for three venture-backed companies and is a founder of Mass Medical Angels. Previously, he was a general partner at Mi3 Venture Partners, an early stage, bioengineering focused fund. Prior to joining Mi3, he was a managing director at Lee Munder Venture Partners, the venture capital arm of Lee Munder Capital Group. He joined Lee Munder from Boston University’s Community Technology Fund, where he made venture capital investments in the life sciences and developed and managed spinouts from the university and Boston Medical Center. Roger began his venture capital career in Eastern Europe with the Bulgarian- American Enterprise Fund, a $55 million venture capital fund. Roger holds an MBA in Finance and Business Development from the Columbia Business School and an AB from Harvard College. He is also the Executive Director of the Boston Biomedical Innovation Center (www.b-bic.org). Representative Fund investments include CoStim Pharmaceuticals, Daktari Diagnostics, Provasculon, TargAnox, and VisionScope. Imran Nasrullah Director, Innovation Sourcing, Boehringer-Ingelheim Pharmaceuticals As a member of Boehringer’s Therapeutic Alliances and Strategic Partnerships team, Imran is responsible for forging business relationships within the Boston/Cambridge life-science ecosystem to facilitate access to new scientific innovation emerging from the Boston area. Previously, Imran served as Senior Advisory Board member at Cellanyx and as Head of Strategic Alliances at T1D Exchange. As Head of Strategic Alliances, Imran’s responsibilities included forging new business relationships with industry, academic and not-for-profit partners, as well as maintaining partnerships with existing partners in these same sectors. Mark Ralph Director, External Partnership Operations, Boehringer Ingelheim Pharmaceutecals Mark Ralph is a member of the Research Networking and Strategic Planning department in Boehringer Ingelheim’s Ridgefield research organization. In his current function, he is responsible for identifying new discovery stage collaboration opportunities with academic and biotech partners. As leader of the External Partnerships and Contract Operations (EPCO) group, Mark also represents Research interests in the negotiation and execution of agreements with universities and technology companies. Mark joined Boehringer Ingelheim in 2001 as a medicinal chemist. Since this time, he has transitioned into several diverse roles with increasing responsibility. As a manager for external chemistry resources, he helped drive global productivity increases from contract research organizations around the world. This was followed by a stint in finance where he provided fiscal guidance to brand teams in the prescription medicine organization. Mark holds a MS degree in chemistry from Memorial University (Canada) and a MBA with concentration in finance from the University of Connecticut. He is included as an inventor on five patents and an author on three scientific publications. 18 Biographies June 2, 2015 Harvard Club of Boston Ruben Salinas III Co-founder, President & CEO Mr. Salinas is the cofounder, President & CEO of Parsagen Diagnostics, a company focused developing and commercializing breakthrough invitro diagnostics in the women’s health arena. Most recently, he served as Executive Vice President of AmniSure International, a company that disrupted the landscape of obstetrical diagnostics through the introduction of proprietary rapid assays based on the PAMG-1 protein marker. The company was acquired by Qiagen N.V. in May, 2012. Prior to AmniSure, he was President & CEO of MPI, a world-leader in diagnostic-imaging surfaces. Previously, he was Director of Strategic Marketing at C.R. Bard and held diverse Product Management, Six Sigma and Operations positions at GE Healthcare and other GE divisions. He holds an MBA from the Harvard Business School and a BS Industrial Engineering from the Instituto Technologico y de Estudios Superiores de Monterrey, and is a nationally-certified Emergency Medical Technician. Scott Samuels Partner, Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C. Scott’s practice focuses on corporate and securities law matters, primarily for life sciences and technology companies. Scott has represented both private and public companies, venture capital funds, angel investors and other parties in a broad range of transactions, including the formation and growth of start-up and emerging companies, private and public offerings, and mergers and acquisitions. For start-up and earlier stage companies, Scott advises on formation, financing, equity compensation, contracts and employee/consultant agreements, and also coordinates with the firm’s specialists in IP, employment, immigration and other areas as needed. Aaron Sandoski Co-founder & Managing Director, Norwich Ventures Aaron Sandoski is Co-founder & Managing Director of Norwich Ventures, a specialized venture capital firm focused on early-stage MedTech. Aaron sits on the boards of Daktari Diagnostics, Pelvalon, Podimetrics, Soffio Medical, and Vaxess Technologies. Previous investments include Rhythmia Medical (acquired by Boston Scientific) and Intelligent Bio-systems (acquired by Qiagen). Prior to founding Norwich Ventures, Aaron worked for DEKA R&D, the engineering think tank of Dean Kamen. He has also worked in start-up operations where he helped launch a subsidiary of Express Scripts and helped launch a venture-backed payments company. Aaron began his career as a consultant at McKinsey & Company, where he advised healthcare clients ranging from leading medical device companies to a rural hospital system. Aaron is co-author of How the Wise Decide (Crown Business), a book on best practices in making tough decisions. Aaron earned an MBA from Harvard Business School and graduated summa cum laude from Dartmouth College with a double A.B. in Chemistry and Economics. Biographies 19 8th Annual Massachusetts Life Sciences Innovation Day Kevin Scanlon Founder & CEO, International BioScience Dr. Kevin Scanlon’s career spans roles in academic medicine, senior management in the pharmaceutical industry and biotech companies, as well as an individual investor. Dr. Scanlon was identified by LA Techweek in 2013 as an individual impacting the Los Angeles business and the technology landscape on a significant scale. During the two years Dr. Scanlon served as the Chairman of Pasadena Angels Investment Group, ~100 investors funded over 50 companies for $9.0 MM. He has been CEO of four biotechnology companies, including Melanoma Diagnostics, which was sold to Myriad Genetics. At Berlex-Schering AG (Berlin, Germany), he was responsible for the genomic and cancer programs in the US, Europe and Asia. Dr. Scanlon’s notable academic achievements include: Leukemia Society Scholar, Paul Martini Medical Research Prize (Cancer, Germany), Co-Founder and Editor of the Nature Journal “Cancer Gene Therapy”, President of the International Society of Cell and Gene Therapy, co-authoring 135 peer-reviewed scientific articles and nine medical books. Dr. Scanlon also holds seven issued US Patents. Katie Stebbins Assistant Secretary of Innovation, Technology, and Entrepreneurship, Massachusetts’ Executive Office of Housing and Economic Development Katie has twenty years of experience in city and regional, and workforce and economic development. She served the City of Springfield for ten years, specializing in environment planning and brownfield redevelopment, worked for the Cecil Group in Boston, and served as the Western Massachusetts Director for Mass. Mentoring Partnership. Most recently, Katie ran her own consulting practice and was the primary consultant for the Holyoke Innovation District on behalf of the Massachusetts Tech Collaborative. She is also an entrepreneur, who actively participates in the mentoring and accelerator space, and launched her own civic tech startup in 2012. She is a resident of Western Massachusetts. John Tagliamonte Chief Business Officer, Oxyrane Mr. Tagliamonte has over 15 years of experience in executive leadership positions with responsibility for finance, business development, commercial and business operations, strategic planning and legal functions with established and emerging public and private life sciences companies. He is Chief Business Officer of Oxyrane a biopharmaceutical company developing treatments for rare diseases and on the Advisory Board of Cocoon Biotech. He previously served on the advisory board of BioHelix Corp. Previously he was VP Business Development at Anchor Therapeutics and ImmunoGen and Director worldwide BD&L at Johnson & Johnson. He began his career as a research scientist at Dana-Farber Cancer Institute followed by global commercial roles at Bio-Rad. Mr. Tagliamonte received his M.B.A. from Boston College and his B.S. in molecular biology from Tufts University. 20 Biographies June 2, 2015 Harvard Club of Boston Seth Taylor CFO & CBO, Mass Innovation Labs Seth has over 17 years of industry experience that combines corporate business development, corporate advisory services, and founding life science companies. As Managing General Partner at Vectur LLC and before that a Principal at TSG Partners, he developed growth strategies and worked on a wide range of strategic mandates for leading life science companies. He was co-founder of Molecularware, Inc., a life science informatics company, and prior to that an executive in business development at Packard Bioscience. He received his BS from Cornell University, his PhD from The Johns Hopkins University, and his SM from the Sloan School of MIT. Josh Tolkoff Managing Director, Ironwood Equity Fund Josh works at CIMIT, Center for Integration of Medical and Innovative Technology, accelerating the commercialization of suitable projects. In addition, he is a Managing Director of Ironwood Equity Fund, a later stage venture investor in healthcare and specialty manufacturing companies. Prior to Ironwood, Josh founded and managed Seedling Enterprises, considered one of the most successful medical device accelerators funds. Josh founded ACT Medical, which became a premier medical device contract developer and manufacturer. In 10 years he lead ACT’s growth to over $20 million before it was sold to MedSource. Josh started Harbor Medical Devices, a venture backed medical device company. Prior to founding Harbor, Josh was head of research and development for over 9 years for Medi-Tech, the founding division of Boston Scientific. He held this role as the company grew from 20 to over 500 employees. He currently is a corporate Director of numerous for-profit growth companies. He is a board member and past chair of MassMedic and the advisory board of the Harvard-MIT program in Health Sciences and Technology. He is the founding board chair of Interise, a non-profit helping small urban companies develop and execute a new growth plan. Interise has grown from 1 to over 20 cities through a partnership with the SBA. Josh received a Bachelor degree with concentration in Engineering and Applied Physics from Harvard College in 1970 and a Masters degree in Mechanical Engineering with a major in BioMechanics from MIT in 1971. Roger Tung Co-Founder, President & CEO, Concert Pharmaceuticals Dr. Tung is the scientific founder, President, and CEO of Concert Pharmaceuticals (NASDAQ: CNCE). Previously, Roger was a founding scientist at Vertex Pharmaceuticals, where he worked from 1989 to 2005, most recently as Vice President of Drug Discovery. Prior to Vertex, Roger held various positions at Merck, Sharp & Dohme Research Laboratories and The Squibb Institute for Medicinal Chemistry. At Vertex, he co-invented the FDA-approved HIV protease inhibitors Lexiva® and Agenerase® and oversaw the discovery of Incivek® and Kalydeco®, which were approved, respectively, to treat hepatitis C infection and cystic fibrosis caused by gating mutations of the CFTR. Roger has published and presented widely in the US and abroad and is an inventor on over 75 issued U.S. patents. He received his B.A. in chemistry from Reed College and his Ph.D. in Medicinal Chemistry from the University of Wisconsin-Madison, where he serves on the Board of Visitors. Roger has been a Scientific Advisory Board member to both public and private biotechnology companies and has a long-standing interest in company formation and entrepreneurialism. Biographies 21 8th Annual Massachusetts Life Sciences Innovation Day Eric Walters CEO, Co-Founder & Director, ONEighty C Technologies Corporation Eric G. Walters is CEO, a Co-Founder and Director of ONEighty C Technologies Corporation. The Company owns WAVEPulseTM Technology, an advanced medical sterilization platform. He has been involved in private and public company fund raising for more than 20 years. Mr. Walters has raised more than $100M in capital. Mr. Walters was formerly EVP/CFO and a member of the original senior management team that grew a $1M medical device start-up company (PolyMedica) to $350M in profitable revenues, later sold for $1.5B in cash when its revenues exceeded $675M. Mr. Walters is a CPA and has managed investor relations for a publiclyheld corporation with a $1B market capitalization. He was formerly a Big Four auditor and serves on several Boards of Directors. Mr. Walters has been a C-level executive of both life science and clean technology companies. Darshana Zaveri Partner, Catalyst Health Ventures Darshana Zaveri is a Partner and a member of Catalyst’s investment committee. Darshana is actively involved in all aspects of Fund Management including Investments and Capital Raising. She led Catalyst’s investments in Augmenix, Lantos Technologies, nVision Medical, Maxwell Health, Aria CV and Hepregen. She currently represents Catalyst on the Boards of Lantos (past Chair), nVision, Aria CV, Augmenix and Maxwell Health and was actively involved with portfolio company Allegro Diagnostics (acquired by Veracyte Inc.). Prior to Catalyst, she was an Investigator at Vertex Pharmaceuticals and an integral part of the drug development programs in oncology, metabolic disease, and immunology. Previously she worked at Genome Therapeutics, a Massachusetts-based biotechnology company, at the Dana Farber Cancer Institute and completed an internship at the United Nations. She has authored several publications and scientific journal articles and currently serves as a Catalyst of the Deshpande Center for Technological Innovation at MIT. Darshana received an MPA from Harvard University, a Master in Cell and Molecular Biology from Boston University, and a BS in Biochemistry from Bombay University in Bombay, India. 22 Biographies June 2, 2015 Harvard Club of Boston MALSI Day Planning Committee Chair Abi Barrow, Massachusetts Technology Transfer Center Content Richard Anders, MA Medical Angels Abi Barrow, Massachusetts Technology Transfer Center Carl Berke, Partners Healthcare Roger Frechette, New England PharmAssociates Lauren Laidlaw, Decision Resources Group Alan Lucas, CMC Consulting Group Imran Nasrullah, Boehringer Ingelheim Marketplace Shelley Amster, ShelleyCO, LLC Research & Startup Showcase and Logistics Tatiana Demidova, Harvard University Julia Goldberg, Massachusetts Technology Transfer Center Alex Simon, Harvard Biotech Club Reception Denise Aronson, Safety Partners, Inc. Lauren Laidlaw, Safety Partners, Inc. Team Anu Ahuja, Brandeis University Nina Green, Consultant Suzanne Grillo, Institute for Pediatric Innovation Kevin O’Sullivan, MA Biotech Incubator Avi Spier, Novartis Maude Tessier, Merck Planning Committee 23 8th Annual Massachusetts Life Sciences Innovation Day 24 Sponsors & Organizers June 2, 2015 Harvard Club of Boston Sponsors and Organizers Gold Sponsors....................................................................................................................................... 26 Massachusetts Life Sciences Center........................................................................................................................26 Pepper Hamilton LLP....................................................................................................................................................27 Silver Sponsors...................................................................................................................................... 28 Boehringer Iingelheim Pharmaceuticals................................................................................................................28 MassBio..............................................................................................................................................................................28 Mass Innovation Labs, LLC .........................................................................................................................................29 MintzMintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.................................................................................29 Conference Supporters...................................................................................................................... 30 Lathrop & Gage LLP ......................................................................................................................................................30 MassGlobal Partners......................................................................................................................................................30 Organizers............................................................................................................................................... 31 Massachusetts Technology Transfer Center..........................................................................................................31 Mass Medical Angels ....................................................................................................................................................32 Harvard Biotechnology Club......................................................................................................................................32 MALSI..................................................................................................................................................................................33 In association with .............................................................................................................................. 34 Boston Life Science Networking ..............................................................................................................................34 CIMIT...................................................................................................................................................................................34 Harvard Alumni Entrepreneurs.................................................................................................................................34 Lemelson-MIT..................................................................................................................................................................34 M2D2...................................................................................................................................................................................34 MASS-AWIS ......................................................................................................................................................................34 Massachusetts Biomedical Initiatives .....................................................................................................................34 MassChallenge Inc.........................................................................................................................................................34 MassMedic........................................................................................................................................................................34 Massachusetts Technology Collaborative ............................................................................................................34 Massachusetts Technology Leadership Council..................................................................................................34 NEHEN................................................................................................................................................................................34 North Shore InnoVentures .........................................................................................................................................34 OPEN ..................................................................................................................................................................................34 Safety Partners, Inc. .......................................................................................................................................................34 The Bioscience Network ..............................................................................................................................................34 The Capital Network .....................................................................................................................................................34 TiE.........................................................................................................................................................................................34 VentureWell .....................................................................................................................................................................34 WEST...................................................................................................................................................................................34 University of Massachusetts.......................................................................................................................................34 Sponsors & Organizers 25 8th Annual Massachusetts Life Sciences Innovation Day Gold Sponsor 26 Sponsors & Organizers June 2, 2015 Harvard Club of Boston Gold Sponsor Biologically Ever get the feeling that your lawyers don’t understand what you do? They may know the law, but science or your business? Not so much. You need a law firm steeped in life sciences, who will be your ally at every step from the lab bench to the board room — from the molecule to the market. A law firm with more than half a century of experience in helping scientists and their businesses succeed. You need lawyers who know you and the science — Pepper Hamilton LLP. We are proud to support Massachusetts Life Sciences. www.pepperlaw.com Berwyn | Boston | Detroit | Harrisburg | Los Angeles | New York | Orange County Philadelphia | Pittsburgh | Princeton | Silicon Valley | Washington | Wilmington Sponsors & Organizers 27 8th Annual Massachusetts Life Sciences Innovation Day Silver Sponsors 28 Sponsors & Organizers June 2, 2015 Harvard Club of Boston Silver Sponsors We are proud to support The Massachusetts Technology Transfer Center and the innovators who transform today’s ideas into tomorrow’s discoveries. Boston | London | Los Angeles | New York | San Diego | San Francisco | Stamford | Washington | www.mintz.com Sponsors & Organizers 29 8th Annual Massachusetts Life Sciences Innovation Day Conference Supporters Lathrop & Gage is proud to support Massachusetts Life Sciences Innovation Day We salute this opportunity for the science and business communities to connect and collaborate. CA LIFOR NI A | COLOR A DO | ILLINOIS | K A NSAS M ASSACHUSETTS | MISSOU R I | N EW YOR K ( 8 57 ) 3 0 0 - 4 0 0 0 | L AT H RO P G AG E .C O M The choice of a lawyer is an important decision and should not be based solely upon advertisements. For more information, contact Giulio DeConti at (857) 300-4000. www.massglobalpartners.com 30 Sponsors & Organizers June 2, 2015 Harvard Club of Boston Organizer The Massachusetts Technology Transfer Center is funded by the Commonwealth of Massachusetts. Its goal is to support technology transfer activities from public and private research institutions to companies in Massachusetts. To achieve this goal, the Center works with technology transfer offices at Massachusetts research institutions; faculty, researchers, and students who have commercially promising ideas; and companies across the Commonwealth. _______________________________________________________________________________ The Center: • facilitates and accelerates technology transfer between research institutions and Massachusetts companies; • promotes collaboration between research institutions and the Commonwealth’s technology industry; • assists in the growth of Massachusetts companies, including startups, by enhancing technological leadership; and • supports regional and statewide economic development priorities. _______________________________________________________________________________ The Center supports the commercialization of research technologies through a variety of programs: The Center provides mentoring to researchers who believe they have a technology that could serve as the basis of a new company. The process includes the development of a business presentation for an expert board of external reviewers. Commercialization and Entrepreneurial Education seminars and workshops enable researchers to understand the process of commercializing technologies. Expert technology reviews provide opportunities for Massachusetts research institutes to have external industry experts evaluate technologies and give advice regarding their commercial potential. Technology Forums allow investors and potential corporate partners to meet with companies formed around technologies developed in Massachusetts research institutes. www.MTTC.org www.MassTechPortal.org MaTTCenter@umassp.edu twitter.com/MassTTC Sponsors & Organizers 31 8th Annual Massachusetts Life Sciences Innovation Day Organizers 32 Sponsors & Organizers June 2, 2015 Harvard Club of Boston We are motivated to leverage what is truly unique about MA “If I stand in the middle of Mass Ave Bridge, and walk 1 mile in either direction, I have everything I need to start a billion dollar life sciences company” The Massachusetts Life Sciences Start-up Initiative (MALSI) is a collaborative group of public and private entities that work with emerging biotech and biomed companies. The prime aim of MALSI is to ensure that every life sciences entrepreneur or researcher who has a commercializable idea has easy and rapid access to the vast network of organizations and individuals who can help them realize their dreams. The Massachusetts Technology Transfer Center, Mass MEDIC, TiE Boston, and MassBio have partnered to present the Massachusetts Life Sciences Innovation Day. In case you have any questions, please contact Massachusetts Technology Transfer Center at mattcenter@umassp.edu Please join our MALSI Group on LinkedIn.com Sponsors & Organizers 33 8th Annual Massachusetts Life Sciences Innovation Day In association with 34 Sponsors & Organizers June 2, 2015 Harvard Club of Boston Poster Presenters Anschel Technology, Inc..................................................................................................................... 40 David Anschel, Founder Aria Neurosciences, Inc...................................................................................................................... 40 Bijan Almassian, President & CEO BeTH.......................................................................................................................................................... 40 Jason Hill, CEO Brigham and Women’s Hospital...................................................................................................... 40 Julian Daich, Research Fellow Harvard Medical School..................................................................................................................... 40 Victor Li, Postdoc fellow Harvard Medical School..................................................................................................................... 41 Nathan Palmer, Researcher Harvard Medical School..................................................................................................................... 41 David Roberson, Graduate Student Harvard University............................................................................................................................... 41 Charles Clarke, Researcher Little Sparrows Technologies........................................................................................................... 41 Donna Brezinski, CEO Massachusetts Eye and Ear Infirmary............................................................................................ 41 Joseph Ciolino, Assistant Professor MIFCOR..................................................................................................................................................... 42 Jernej Godec, Co-founder Sechel Therapeutics, Inc..................................................................................................................... 42 Ephraim Trakhtenberg, Co-founder Strategia Therapeutics, Inc................................................................................................................ 42 Akinori Hishiya, Director Tufts University...................................................................................................................................... 42 Clay Bennett, Assistant Professor University of Massachusetts Medical School............................................................................. 42 Jennifer Broderick, Researcher Poster Presenters 35 8th Annual Massachusetts Life Sciences Innovation Day University of Massachusetts Medical School............................................................................. 43 Marie Didiot, Researcher University of Massachusetts Medical School............................................................................. 43 Neil Marya, Researcher University of Massachusetts Medical School............................................................................. 43 Jie Song, Associate Professor University of Massachusetts Medical School............................................................................. 43 Anton Turanov, Researcher University of Massachusetts Medical School............................................................................. 43 Jianwen Xu, Researcher Wellumina Health, Inc......................................................................................................................... 44 Peter Tarca, CEO Worcester Polytechnic Institute...................................................................................................... 44 Sarah Hernandez, PhD Candidate Wyss Institute for Biologically Inspired Engineering, Harvard University........................ 44 Yevgeny Brudno, Researcher Wyss Institute for Biologically Inspired Engineering, Harvard University........................ 44 Jae-Won Shin, Postdoctoral Fellow 36 Poster Presenters June 2, 2015 Harvard Club of Boston Anschel Technology, Inc Presented by: David Anschel, Founder danschel@yahoo.com Poster Title: SightSaverTM Aria Neurosciences, Inc. Presented by: Bijan Almassian, President & CEO balmassian@arianeurosciences.com Poster Title: Title Novel Disease Modifying Therapy for Alzheimer’s Disease (AD) BeTH Presented by: Jason Hill, CEO jason@bethcare.us Poster Title: BeTH’s Dynamic Prosthetic Liner Reduces Pain for Leg Amputees Brigham and Women’s Hospital Presented by: Julian Daich, Research Fellow julian.daich@bioimag.com Poster Title: Magnetically Functionalized Collagen for the Detection of Enzymatic Activity Harvard Medical School Presented by: Victor Li, Postdoc fellow Victor_li@hms.harvard.edu Poster Title: tion StemCellerant – safe and reliable technology for rapid stem cell differentia- 37 8th Annual Massachusetts Life Sciences Innovation Day Harvard Medical School Presented by: Nathan Palmer, Researcher nathan_palmer@hms.harvard.edu Poster Title: pression A tool for drug response prediction and drug repositioning using gene ex- Harvard Medical School Presented by: David Roberson, Graduate Student dprobers@fas.harvard.edu Poster Title:“Trojan horse” delivery of charged compounds through TRP channels to target multiple diseases: novel compounds to treat pain, itch, and inflammation Harvard University Presented by: Charles Clarke, Researcher chrlesc@hotmail.com Poster Title: Wearable in healthcare Little Sparrows Technologies Presented by: Donna Brezinski, CEO donna@littlesparrowstech.com The Bili-Hut™: Portable, high-intensity phototherapy for home treatment of neonatal jaundice Poster Title: Massachusetts Eye and Ear Infirmary Presented by: Joseph Ciolino, Assistant Professor Joseph_Ciolino@meei.harvard.edu Poster Title: Drug-Eluting Contact Lens 38 Poster Presenters June 2, 2015 Harvard Club of Boston MIFCOR Presented by: Jernej Godec, Co-founder Godec@fas.harvard.edu Poster Title: Developing Novel, Protective Therapeutics for Ischemic Disease Sechel Therapeutics, Inc Presented by: Ephraim Trakhtenberg, Co-founder trakhtenberg@gmail.com Poster Title: Molecular Therapy for Nerve Regeneration: Focus on the Optic Nerve Strategia Therapeutics, Inc. Presented by: Akinori Hishiya, Director akinori.hishiya@strategiatx.com Poster Title: teins TAPBOOST Technology: Enhanced Production for Difficult-to-Produce Pro- Tufts University Presented by: Clay Bennett, Assistant Professor clay.bennett@tufts.edu Poster Title: New Methodology for Stereoselective Complex Carbohydrate Synthesis University of Massachusetts Medical School Presented by: Jennifer Broderick, Researcher jennifer.broderick@umassmed.edu Poster Title:Gene Silencing by Tethering RISC 39 8th Annual Massachusetts Life Sciences Innovation Day University of Massachusetts Medical School Presented by: Marie Didiot, Researcher Marie.didiot@umassmed.edu Exosome-Mediated Delivery of Hydrophobically Modified siRNA for Huntingtin mRNA Poster Title: University of Massachusetts Medical School Presented by: Neil Marya, Researcher Neil.marya@umassmemorial.org Poster Title: The utility of clinical scoring systems in mobile platforms University of Massachusetts Medical School Presented by: Jie Song, Associate Professor Jie.Song@umassmed.edu Poster Title: A high-performance biodegradable polymer/hydroxyapatite composite for versatile skeletal tissue engineering applications University of Massachusetts Medical School Presented by: Anton Turanov, Researcher Anton.Turanov@umassmed.edu Poster Title: eclampsia Development of Therapeutic anti-sFLT1 siRNAs for the Treatment of Pre- University of Massachusetts Medical School Presented by: Jianwen Xu, Researcher Jianwen.Xu@umassmed.edu A versatile hydrogel formulation system combining tunable gelling rate, degradation rate, excellent mechanical properties with unparalleled compatibility with therapeutic additives Poster Title: 40 Poster Presenters June 2, 2015 Harvard Club of Boston Wellumina Health, Inc. Presented by: Peter Tarca, CEO ptarca@wellumina.com Poster Title: Wellumina mHealth Point-of-Care Diagnostic Screening Platform Worcester Polytechnic Institute Presented by: Sarah Hernandez, PhD Candidate sarah.runge@wpi.edu Poster Title: Characterization of Pre-cancer Biomarker Wyss Institute for Biologically Inspired Engineering, Harvard University Presented by: Yevgeny Brudno, Researcher brudno@fas.harvard.edu Poster Title: Refillable Drug Delivery Device Wyss Institute for Biologically Inspired Engineering, Harvard University Presented by: Jae-Won Shin, Postdoctoral Fellow jwshin@seas.harvard.edu Poster Title: Optimizing Cell Delivery By Single-Cell Encapsulation In Microgels 41 8th Annual Massachusetts Life Sciences Innovation Day Innovators’ Marketplace Exhibitors Life Science Products and Services Baren-Boym Product Design....................................................................www.baren-boym.com Boehringer Iingelheim Pharmaceuticals.................................... www.boehringer-ingelheim.com Catapult Product Development........................................................................... www.catpd.com CreaGen Chemistry Incubator ................................................www.creagenchemincubator.com Cummings School of Veterinary Medicine at Tufts University....................... www.cvet.tufts.edu CuriRx, Inc.......................................................................................................... www.curirx.com Fisher Scientific....................................................................................... www.thermofisher.com Integral Biosystems....................................................................... www.integralbiosystems.com Mansfield Bio-Incubator, Inc................................................................................ www.bioinc.org Masy BioServices................................................................................................www.masy.com Mass Innovation Labs, LLC......................................................... www.massinnovationlabs.com MedChem Partners........................................................................ www.medchempartners.com Organix, Inc...............................................................................................www.corganixinc.com Plexus Corp.......................................................................................................www.plexus.com PPD Laboratories............................................................................................... www.cppdi.com qPharmetra............................................................................................. www.cqPharmetra.com Safety Partners, Inc .........................................................................www.safetypartnersinc.com Toxikon Corporation..........................................................................................www.toxikon.com Entrepreneurship Support Massachusetts Life Sciences Center...............................................www.masslifesciences.com Massachusetts Technology Trasfer Center..................................................www.mattcenter.org MassBio........................................................................................................... www.massbio.org MALSI............................................................................. www.linkedin.com/groups?gid=113959 Massachusetts Medical Device Development Center (M2D2)..................... www.uml.edu/m2d2 Harvard Biotechnology Club.................................................................. www.thebiotechclub.org Boston Life Science Networking...................................................... www.bostonlifescience.com 42 Innovator's Marketplace Exhibitors June 2, 2015 Harvard Club of Boston Harvard Alumni Entrepreneurs........................................ www.harvardalumnientrepreneurs.org Lemelson-MIT Program................................................................................. web.mit.edu/invent Life Science Nation .......................................................................... www.lifesciencenation.com MASS-AWIS.................................................................................................www.mass-awis.org Massachusetts Biomedical Initiatives....................................................... www.massbiomed.org Massachusetts Medical Device Development Center (M2D2) .................... www.uml.edu/m2d2 MassMedic................................................................................................www.massmedic.com Massachusetts Technology Leadership Council................................ www.masstechleaders.org Massachusetts Technology Collaborative..................................................... www.masstech.org MassGlobal Partners....................................................................www.massglobalpartners.com MVVF..................................................................................................................... www.mvvf.org North Shore InnoVentures...................................................................................... www.nsiv.org OPEN............................................................................................. www.open-newengland.com TiE.................................................................................................................www.tie-boston.org The Bioscience Network............................................................. www.thebiosciencenetwork.org VentureWell...............................................................................................www.cventurewell.org WEST............................................................................................................... www.westorg.org Funding CIMIT..................................................................................................................... www.cimit.org Mass Medical Angels.........................................................................www.massmedangels.com MassChallenge Inc................................................................................www.masschallenge.org New England Venture Capital Association.............................................www.newenglandvc.org The Capital Network – TCN...............................................................www.thecapitalnetwork.org Professional Services Lathrop & Gage LLP................................................................................. www.lathropgage.com MintzMintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C................................. www.mintz.com Pepper Hamilton LLP..................................................................................www.pepperlaw.com Innovator's Marketplace Exhibitors 43 8th Annual Massachusetts Life Sciences Innovation Day Notes 44 Innovator's Marketplace Exhibitors