pedriatric diseases

PEDRIATRIC DISEASES
3,000
Pediatric cardiac surgeries
per year in France for 1%
of babies have congenital heart defects
80%
Orphan diseases are genetic
and diagnosed in early childhood
10%
children deaths in Europe
still due to infectious pediatric diseases
Pediatric is the first medical
specialty in France, with
a growing academic
consciousness that children
are not just small adults
but need tailored care and
health products.
Yet, pediatric drugs and
medical devices are still
most often derived from
adult lines.
LYON,
IS ONE OF THE
BEST PLACES
FOR CHILD CARE IN
FRANCE & EUROPE
HFME
2nd
Presence of world
childcare hospitals in France
(Hôpital Femme Mère Enfant)
marked 19,69/20 2
France’s 1st
diatrics
Pe
university for health sciences
including all pediatric
specialty trainings
3
rd
French
Region
n.1
in child vaccines (Sanofi Pasteur)3
in Lyon area
Europe’s 1st
integrated institute dedicated
to epilepsies, to be built
in Lyon by 2014
700
Pediatricians
in Rhône-Alpes
260 with an independent
practice1
for pediatrician density 1
1. ALCIMED estimate based on the IDEE foundation and Ordre des Médecins 2012 figures
2. Source: Le Point ranking 2012, http://hopitaux.lepoint.fr/classement-91/pediatrie.ph, 1st and 2nd are Necker and Trousseau Paris hospitals
3. World n°1 in human vaccine and world largest product line in pediatric combination vaccines. Source: Sanofi website
Pediatric’s value chain
in Lyon area
EXPLORATORY
RESEARCH
PRECLINICAL
/ CLINICAL
COMMERCIALIZATION
/ UTILIZATION
Pediatric drugs
Child care services
Pharmaceutical
research
INSERM, UCLB
Medical devices
CHILD CARE
(BABY/CHILD/TEEN)
Pediatric drug production
Sanofi Pasteur, Merck Serono
Industrial services (CROs/CMOs)
Therapeutics application
research
HCL, EPICIME
Eurofins-optimed, PX’Therapeutics (not specific to pediatrics)
Pediatric implants, prothesis and orthopedic devices
Groupe Lépine, Thuasne
Child healthcare services
(Medicine, surgery, emergency)
HFME, IHOP
Electro-medical devices (neonatology, pediatric imaging...)
DTF Medical
Other pediatric segments (hospital furniture, nutrition, baby care...)
Bledina, Tetra Medical, Carina Medical
Education / Training
UCLB, HCL
Networking and regulatory organizations
ANSM, Fondation Mérieux, Fondation APICIL, Fondation IDEE
W
ith a sound presence in the child care
services links of the value chain, Lyon
is developing its activities in pediatric
drugs and medical devices.
• Top level human strengths in pediatrics, with a high
density of pediatricians, an excellent training system and
top level doctors / researchers / teachers.
• Integrated modern infrastructures, whith the 84,000 m²
fully equiped Hôpital Femme Mère Enfant dedicated to
child and mother care inaugurated in 2008.
• The support of a dense scientific and industrial
ecosystem in pharmacy and medical devices.
Psychological, educative and practical
child and family support
HFME, Maison du Petit Monde
W
ith the HFME hospital, Claude Bernard University and INSERM EPICIME,
Lyon hosts high-level public pediatric research and education infrastructures.
•U
niversity Lyon 1 / Claude Bernard: 35,000 students, France's 1st university for health sciences, pediatric medical specialty training
and neonatology, specialty trainings (DU/DIU) in pediatric nephrology, emergencies and pediatric reanimation, pediatric transport,
neonatology, pediatric metabolic diseases…
• INSERN-EPICINE: >50 running studies, within HCL HFME and Louis Pradel hospitals.
•H
ôpital Femme Mère Enfant: opening in 2008, 84,000 m² brand new premises, ranked 3rd pediatric hospital in France in 2012
(mark 19,69/20)1, 452 beds, 300 doctors and surgeons, 1,600 non medical staff 4,000 births per year.
1: Le Point ranking 2012, http://hopitaux.lepoint.fr/classement-91/pediatrie.php
A
mong Lyon’s main life sciences industries, Sanofi and Merck specifically develop
pediatric drugs and Danone is involved in the nutrition aspect of baby health.
•S
anofi Pasteur: No. 1 in human vaccine, with world largest product line in paediatric combination vaccines (Hexaxim, Pentacel…)
• M erck Serono: development of solutions for pediatric endocrinology and Turner syndrome.
•B
lédina (Danone Baby Nutrition): 450 employees in Lyon area, development, production and distribution of nutrition
products for 0-3 years old babies, research activities on child nutrition and related disorders.
• Groupe Lépine: orthopedics, traumatology devices and body constraining means, with babies, children and teenagers product lines.
•T
huasne: a junior product line for orthopedic devices.
•T
etra Medical: design, manufacture and distribution of feeding bottles and other childcare medical devices.
•C
arina Médical: design and manufacturing of medical furnitures, including obstetric chairs and pediatric tables.
•A
dvicenne Pharma: member of Lyonbiopôle, development, production and distribution of pediatric drugs for neurologic and
nephrologic diseases.
H
ealthcare foundations as Fondation Mérieux
or Fondation APICIL support humanitarian actions for child care.
• Foundation Mérieux: strengthening local healthcare capacity in developing countries to reduce the impact of infectious diseases
on vulnerable populations, and primarily on children.
•A
picil: support and funding of research projects on pain treatment, including projects focusing on children pain.
•A
NSM: control of health products dedicated to children, including clinical trials, pediatric investigation plans and market access.
•F
ondation Idée (Epilepsy Institute): 3,1€ million collected, 10 beds in the HFME Lyon hospital at end 2012, 50% epilepsy cases
diagnosed on children or teenagers.
ADERLY - Lyon Area Economic Development Agency
Place de la Bourse - 69289 Lyon Cedex 02 - FRANCE
Tel. 33 (0)4 72 40 57 50 - Fax 33 (0)4 72 40 57 35
aderly@investinlyon.com - www.investinlyon.com
2013 © photo credit Shutterstock
A
few Lyon’s SMEs develop products for child and baby care,
derivated from their “adult” product line.