THRiVE-2 Supervisors
Transcription
THRiVE-2 Supervisors
THRiVE-2 Supervisors Name 1. Kennedy Amone-P’Olak Organisation Gulu University Area of expertise (keywords) Significant publications in area of expertise (list up to five) Educational Psychology 1. Amone-P Olak K, Otim BN, Opio G, Ovuga E, MeiserStedman R. War experiences and psychotic symptoms among former child soldiers in Northern Uganda: the mediating role of post-war hardships – the WAYS Study. South African Journal of Psychology, Published Online first: [24 Oct 2014]. DOI: 10.1177/0081246314556567 2. Amone-P Olak K, Lekhutlile T, Meiser-Stedman R, Ovuga E. Mediators of the relation between war experiences and suicidal ideation among former child soldiers in Northern Uganda: the WAYS study. BMC Psychiatry. 2014 Sep 24;14(1):271. DOI:10.1186/s12888-014-0271-2 3. Amone-P’Olak K, Ovuga E, Croudace TJ, Jones PB, Abbott R. (In Press).The influence of different types of war experiences on depression and anxiety in a Ugandan cohort of war-affected youth: the WAYS study. Social Psychiatry and Psychiatric Epidemiology. Published Online First: [10 April 2014]; 0:1–10. DOI:10.1007/s00127-014-0873-5 4. Amone-P’Olak K, Jones PB, Meiser-Stedman R, Abbott RA, Ayella-Ataro PS, Amone J, Ovuga E. War experiences, general functioning and barriers to care among former child soldiers in Northern Uganda: the WAYS study. J Public Health 2014;0:1–9. DOI:10.1093/pubmed/fdt126 5. Amone-P’Olak K, Stochl J, Ovuga E, Abbott R, MeiserStedman R, Croudace TJ, Jones PB. Postwar environment and long-term mental health problems in former child soldiers in Northern Uganda: the WAYS study. J Epidemiol Community Health 2014; 68(5): 425430. DOI:10.1136/jech-2013-203042 2. Elizabeth Auma Gulu University Opiyo 3. James Okello Gulu University Infectious Diseases and Neglected Tropical Diseases 1. Meyer AC, Kendi CK, Penner JA, Odhiambo N, Otieno B, Omondi E, Opiyo E, Bukusi EA, Cohen CR. The impact of routine cryptococcal antigen screening on survival among HIV-infected individuals with advanced immunosuppression in Kenya. Trop Med Int Health. 2013 Apr;18(4):495-503. 2. Mutika GN, Opiyo E, Robinson AS. Assessing mating performance of male Glossina pallidipes (Diptera: Glossinidae) using a walk-in field cage. Bull Entomol Res. 2001 Aug;91(4):281-8. 3. Bosompem KM, Masake RA, Assoku RK, Opiyo EA, Nantulya VM. Field evaluation of a dot-ELISA for the detection and differentiation of trypanosome species in infected tsetse flies (Glossina spp.). Parasitology. 1996 Feb;112 ( Pt 2):205-11. 4. Wellde BT, Chumo DA, Onyango FK, Reardon MJ, Roberts LM, Njogu AR, Opiyo EA. Trypanosoma vivax: disseminated intravascular coagulation in cattle. Ann Trop Med Parasitol. 1989 Aug;83 Suppl 1:177-83. 5. Wellde BT, Waema D, Chumo DA, Reardon MJ, Oloo F, Njogu AR, Opiyo EA, Mugutu S.Review of tsetse control measures taken in the Lambwe Valley in 1980-1984. Ann Trop Med Parasitol. 1989 Aug;83 Suppl 1:119-25. Child Psychiatry 1. Okello J, De Schryver M, Musisi S, Broekaert E, Derluyn I. Differential roles of childhood adversities and stressful war experiences in the development of mental health symptoms in post-war adolescents in northern Uganda. BMC Psychiatry. 2014 Sep 9;14(1):260. 2. Nakimuli-Mpungu E, Wamala K, Okello J, Alderman S, Odokonyero R, Musisi S, Mojtabai R, Mills EJ. Outcomes, feasibility and acceptability of a group support psychotherapeutic intervention for depressed HIV affected Ugandan adults: a pilot study. J Affect Disord. 2014 Sep;166:144-50 3. Nakimuli-Mpungu E, Wamala K, Okello J, Alderman S, Odokonyero R, Musisi S, Mojtabai R. Developing a culturally sensitive group support intervention for depression among HIV infected and non-infected Ugandan adults: a qualitative study. J Affect Disord. 2014 Jul;163:10-7. doi: 10.1016/j.jad.2014.03.042. Epub 2014 Apr 1. 4. Klasen F, Reissmann S, Voss C, Okello J. The Guiltless Guilty: Trauma-Related Guilt and Psychopathology in Former Ugandan Child Soldiers. Child Psychiatry Hum Dev. 2014 May 16. 5. Okello J, Nakimuli-Mpungu E, Musisi S, Broekaert E, Derluyn I. The association between attachment and mental health symptoms among school-going adolescents in northern Uganda: the moderating role of war-related trauma. PLoS One. 2014 Mar 10;9(3):e88494. 4. Grace AkelloAyebare Gulu University Medical Anthropology 1. Akello., G, K.J. Fisher & Z. Goldstein (2014) Silenced: psychosocial interventions and neglected priorities in wartorn northern Uganda. Innovia 22:5-10. 2. Van den Berg, S., G. Akello & S. Sonpar (2013) The first decade of intervention: facts, figures, trends. Intervention11(1) 52-76. 3. Akello, G.(2012) The importance of the autobiographic self during research among wartime children in northern Uganda. Medische Atropologie 24(2) 289-300. 4. Akello, G., Richters A. & Ovuga E. (2011) Children's management of compliants symptomatic of psychological distress. A critical analysis of the different approaches in northern Uganda. African journal of traumatic stress 1(2) 74-84. 5. Akello, G., Richters, A., Reis R., (2010) Silencing distressed children in the context of war: An analysis of its causes and health consequences. Social Sciences & medicine 71(2): 213-220. 5. Constantine Steven Loum Labongo Gulu University Medical Anthropology 1. Loum, L.S.C. (2014). Caregiving and the experience of health and illness in children living with HIV/AIDS in Gulu district northern Uganda: an ethnographic research narrative. The Patient Experience Journal, Vol. 1(1; 20): 153-162. Available at: http://pxjournal.org/journal/vol1/iss1/20. 2. Olayo, R., Wafula, C., Aseyo, E., Loum, C. And Kaseje D. (2014). A quasi-experimental assessment of the effectiveness of the community health strategy on health outcomes in Kenya. BMC Health Services Research; 14(Suppl 1):S3) doi:10.1186/1472-6963-14-S1-S3 3. Loum, L.S.C. (2013). Understanding the linkages in organizational and human relations: A review of social network analysis. The Qualitative Report, 19(Rev. 1), 1-6. http://www.nova.edu/ssss/QR/QR19/constantine1.pdf.. 4. Loum, L.S.C. (2013). Strategies for data gathering and reporting voices from the field: A review of Applied Ethnography: Guidelines for field research. The Qualitative Report, 18(Rev. 22), 1-7. http://www.nova.edu/ssss/QR/QR18/constantine22.pdf. 5. Loum, L.S.C. (2013). Choices, responsibility, and tradeoffs: A review of designing research in the social sciences. The Qualitative Report, 18(Rev. 13), 1-4. http://www.nova.edu/ssss/QR/QR18/loum13.pdf 6. Emilio Ovuga Gulu University Mental Health 1. Elialilia S. Okello, Catherine Abbo, Wilson W. Muhwezi, 2. 3. 4. 5. 7. Eugene Kinyanda UVRI (MRC Programme) mental health/HIV interface, mental health epidemiology, suicidology Grace Akello, Emilio Ovuga. Mental health literacy among secondary school students in North and Central Uganda: a qualitative study, World Cultural Psychiatry Research Review 2014, 9 (3): 70-80 Yukari C Manabe, James D Campbell, Emilio Ovuga, Samuel Maling, Robert C Bollinger, Nelson Sewankambo; Optimisation of the Medical Education Partnership Initiative to address African health-care challenges; www.thelancet.com/lancetgh Vol 2 July 2014, e392 Sarah Wilker, Iris Kolassa, Dominique de Quervain, Andreas Papassotiropoulos, Anett Pfeiffer, Birke Lingenfelder, Emilio Ovuga, Thomas Elbert, The Role of FKBP5 Genotype in Moderating Long-Term Effectiveness of Exposure-Based Psychotherapy for Posttraumatic Stress Disorder; Translational Psychiatry (2014) 4, e403; doi:10.1038/tp.2014.49 Amone-P Olak K, Otim BN, Opio G, Ovuga E, MeiserStedman R. War experiences and psychotic symptoms among former child soldiers in Northern Uganda: the mediating role of post-war hardships the WAYS Study. South African Journal of Psychology, Published Online first: [24 Oct 2014]. [Epub ahead of print]. DOI: 10.1177/0081246314556567 Amone-P Olak K, Lekhutlile T, Meiser-Stedman R, Ovuga E. Mediators of the relation between war experiences and suicidal ideation among former child soldiers in Northern Uganda: the WAYS study. BMC Psychiatry. 2014 Sep 24;14(1):271. [Epub ahead of print] DOI:10.1186/s12888014-0271-2 1. Kinyanda E, Weiss HA, Mungherera M, Onyango-Mangen P, Ngabirano E, Kajungu R, Kagugube J, Muhwezi W, Muron J, Patel V. Prevalence and risk factors of attempted 2. 3. 4. 5. 8. Janet Seeley UVRI (MRC Programme) social aspects of health, HIV, non-communicable diseases (NCDs), poverty, gender suicide in adult war-affected population of eastern Uganda. Crisis. 2013;34(5):314-23. Kinyanda E, Kizza R, Abbo C, Ndyanabangi S, Levin J. Prevalence and risk factors of depression in childhood and adolescence as seen in four districts of North-Eastern Uganda. BMC Int Health Hum Rights. 2013; 13:19. Kinyanda E, Hoskins S, Nakku J, Nawaz S, Patel V. Prevalence and risk factors of major depressive disorder in HIV/AIDS as seen in semi-urban Entebbe district, Uganda. BMC Psychiatry. 2011; 11:205. Kinyanda E, Wamala D, Musisi S, Hjelmeland H. Suicide in urban Kampala, Uganda: a preliminary exploration. Afr Health Sci. 2011; 11(2):219-27. Maling S, Todd J, Van der Paal L, Grosskurth H, Kinyanda E. HIV-1 seroprevalence and risk factors for HIV infection among first-time psychiatricadmissions in Uganda. AIDS Care. 2011; 23(2):171-8. 1. Kasedde, S., A. M. Doyle, J. A. Seeley and D. Ross (2014). "They are not always a burden: Older people and child fostering in Uganda during the HIV epidemic." Social Science and Medicine 113: 161-168. 2. Mbonye, M., R. Rutakumwa, H. Weiss and J. Seeley (2014). "Alcohol consumption and high risk sexual behaviour among female sex workers in Uganda." African Journal of AIDS Research 13(2): 145-151. 3. Riha, J., A. Karabarinde, G. Ssenyomo, S. Allender, G. Asiki, A. Kamali, E. H. Young, M. S. Sandhu and J. Seeley (2014). "Urbanicity and Lifestyle Risk Factors for Cardiometabolic Diseases in Rural Uganda: A CrossSectional Study." PLoS Medicine 11(7): e1001683. 4. Bernays, S., J. Seeley, T. Rhodes and Z. Mupambireyi (2014). "What am I ‘living’ with? Growing up with HIV in Uganda and Zimbabwe." Sociology of Health and Illness (in press). 5. de Vries, J., A. Abayomi, J. Brandful, K. Littler, E. Madden, P. Marshall, O. Oukem-Boyer and J. Seeley (2014). "A perpetual source of DNA or something really different: ethical issues in the creation of cell lines for African genomics research." BMC Medical Ethics 15(1): 60. 9. Anatoli Kamali UVRI (MRC Programme) HIV epidemiology, NCD epidemiology, Microbicide and vaccine trials 1. Price MA, Wallis CL, Lakhi S, Karita E, Kamali A, Anzala O, Sanders EJ, Bekker L, Twesigye R, Hunter E, Kaleebu P, Kayitenkore K, Allen S, Ruzagira E, Mwangome M, Mutua G, Amornkul PN, Stevens G, Pond S, Schaefer M, Papathanasopoulos M, Stevens W, Gilmour J. Transmitted HIV Type 1 drug resistance among individuals with recent HIV infection in East and Southern Africa. AIDS Research and Human Retroviruses 2011; 27:5-12. 2. Ramjee G, Kamali A, McCormack S: The last decade of microbicide clinical trials in Africa: from hypothesis to facts. AIDS 2010; 24(Suppl 4):S40–S49. 3. McCormack S, Ramjee G, Kamali A, Rees H, Crook AM, Gafos M, Jentsch U, Pool R, Chisembele M, Kapiga S, Mutemwa R, Vallely A, Palanee T, Sookrajh Y, Lacey CJ, Darbyshire J, Grosskurth H, Profy A, Nunn A, Hayes R, Weber J. PRO2000 vaginal gel for prevention of HIV-1 infection (Microbicides Development Programme 301): a phase 3, randomised, double-blind, parallel-group trial. Lancet 2010; 376(9749):1329-1337. 4. Parkes-Ratanshi R, Bufumbo L, Nyanzi-Wakholi B, Levin J, Grosskurth H, Lalloo DG, Kamali A. Barriers to starting ART and how they can be overcome: individual and operational factors associated with early and late start of treatment. Tropical Medicine and International Health 2010 Nov;15(11):1347-1356. 5. Kamali A. What is new in HIV⁄AIDS research in developing countries? Tropical Medicine and International Health 2010; 15(8):975-980. 10. Pala Pietro 11. Jennifer Serwanga UVRI (MRC Programme) UVRI (MRC Programme) Immunology Immunology 1. Pala P, Message S, Johnston S, Openshaw P. Increased aeroallergen-specific IL-4 producing T cells in asthmatic adults. Clinical Experimental Allergy 2002; 32:1739-1744. 2. Pala P, Bjarnason R, Sigurbergsson F, Sigurs N, Openshaw PJM. Enhanced IL-4 responses in children with a history of respiratory syncytial virus bronchiolitis in infancy. European Respiratory Journal 2002; 20:376-382. 3. Pala P, Hussell T, Openshaw P. Flow cytometric Measurement of Intracellular Cytokines: application to immunopathology. Journal of Immunological Methods 2000; 243:107-124. 4. Pala P, Verhoef A, Lamb JR, Openshaw PJM. Single cell analysis of cytokine expression kinetics by human CD4+ T cell clones during activation or tolerance induction. Immunology 2000; 49:1-12. 5. Bruck C, Thiriart C, Fabry L, Francotte M, Pala P, Van Opstal O, Culp J, Rosenberg M, De Wilde M, Heidt P, Heeney J. HIV-1 envelope-elicited neutralizing antibody titres correlate with protection and virus load in chimpanzees. Vaccine 1994; 12:1141-1148. 1. Serwanga J, Mugaba S, Betty A, Pimego E, Walker S, Munderi P, Gilks C, Gotch F, Gorsskurth H, Kaleebu P. CD8 T-Cell Responses before and after Structured Treatment Interruption in Ugandan Adults Who Initiated ART with CD4 T Cells <200 Cell/μL: The DART Trial STI Substudy. AIDS Research and Treatment 2011;2011:875028. 2. Chen H, Xiang ZQ, Li Y, Kurupati RK, Jia B, Bian A, Zhou DM, Hutnick N, Yuan S, Gray C, Serwanga J, Auma B, Kaleebu P, Zhou X, Betts MR, Ertl HC. Adenovirus-based vaccines: comparison of vectors from three species of adenoviridae. Journal of Virology 2010; 84(20):10522-32. 3. Walker LM, Phogat SK, Chan-Hui PY, Wagner D, Phung P, Goss JL, Wrin T, Simek MD, Fling S, Mitcham JL, Lehrman JK, Priddy FH, Olsen OA, Frey SM, Hammond PW, Protocol G Principal Investigators, Kaminsky S, Zamb T, Moyle M, Koff WC, Poignard P, Burton DR. Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target. Science 2009; 326(5950):285-9. 4. Serwanga J, Shafer LA, Pimego E, Auma B, Watera C, Rowland S, Yirrell D, Pala P, Grosskurth H, Whitworth J, Gotch F, Kaleebu. Host HLA B*allele-associated multiclade Gag T-cell recognition correlates with slow HIV-1 disease progression in antiretroviral therapy-naïve Ugandans. Public Library of Science One 2009;4(1):e4188. 5. Ndembi N, Lyagoba F, Nanteza B, Kushemererwa G, Serwanga J, Katongole-Mbidde E, Grosskurth H, Kaleebu P, Uganda HIV Drug Resistance Working Group. Transmitted antiretroviral drug resistance surveillance among newly HIV type 1-diagnosed women attending an antenatal clinic in Entebbe, Uganda. AIDS Research and Human Retroviruses 2008; 24(6):889-895. 1. 12. Margaret Nampijja UVRI (MRC Programme) Neurocognitive development in children Mpairwe H, Ndibazza J, Webb EL, Nampijja M, Muhangi L, Apule B, Lule S, Akurut H, Kizito D, Kakande M, Jones FM, Fitzsimmons CM, Muwanga M, Rodrigues LC, Dunne DW, Elliott AM. Maternal hookworm modifies risk factors for childhood eczema: results from a birth cohort in Uganda. Pediatr Allergy Immunol. 2014; 2. 3. 4. 5. 13. Jacqueline K Lugemwa UVRI (MRC Programme) immunology (5):481-8. Muhangi L, Lule SA, Mpairwe H, Ndibazza J, Kizza M, Nampijja M, Nakazibwe E, Kihembo M, Elliott AM, Webb EL. Maternal HIV infection and other factors associated with growth outcomes of HIV-uninfected infants in Entebbe, Uganda. Public Health Nutr. 2013; 16(9):154857. Nampijja M, Apule B, Lule S, Akurut H, Muhangi L, Webb EL, Lewis C, Elliott AM, Alcock KJ. Effects of maternal worm infections and anthelminthic treatment during pregnancy on infant motor and neurocognitive functioning. J Int Neuropsychol Soc. 2012;18(6):101930. Nampijja M, Apule B, Lule S, Akurut H, Muhangi L, Elliott AM, Alcock KJ.Adaptation of Western measures of cognition for assessing 5-year-old semi-urban Ugandan children. Br J Educ Psychol. 2010; 80(Pt 1):15-30. Elliott AM, Kizza M, Quigley MA, Ndibazza J, Nampijja M, Muhangi L, Morison L, Namujju PB, Muwanga M, Kabatereine N, Whitworth JA. The impact of helminths on the response to immunization and on the incidence of infection and disease in childhood in Uganda: design of a randomized, double-blind, placebo-controlled, factorial trial of deworming interventions delivered in pregnancy and early childhood. Clin Trials. 2007;4(1):42-57. 1. Webb EL, Kyosiimire-Lugemwa J, Kizito D, Nkurunziza P, Lule S, Muhangi L,Muwanga M, Kaleebu P, Elliott AM. The effect of anthelmintic treatment during pregnancy on HIV plasma viral load: results from a randomized, doubleblind,placebo-controlled trial in Uganda. J Acquir Immune Defic Syndr. 2012; 60(3):307-13. 2. Webb EL, Mawa PA, Ndibazza J, Kizito D, Namatovu A, Kyosiimire-Lugemwa J,Nanteza B, Nampijja M, Muhangi L, Woodburn PW, Akurut H, Mpairwe H, Akello M, Lyadda N, Bukusuba J, Kihembo M, Kizza M, Kizindo R, Nabulime J, Ameke C, Namujju PB, Tweyongyere R, Muwanga M, Whitworth JA, Elliott AM. Effect of single-dose anthelmintic treatment during pregnancy on an infant's response to immunisation and on susceptibility to infectious diseases in infancy: a randomised, double-blind, placebo-controlled trial. Lancet. 2011; 377(9759):52-62. 3. Kaleebu P, Nankya IL, Yirrell DL, Shafer LA, KyosiimireLugemwa J, Lule DB,Morgan D, Beddows S, Weber J, Whitworth JA. Relation between chemokine receptor use, disease stage, and HIV-1 subtypes A and D: results from a rural Ugandan cohort. J Acquir Immune Defic Syndr. 2007; 45(1):28-33. 4. Talisuna AO, Kyosiimire-Lugemwa J, Langi P, Mutabingwa TK, Watkins W, Van Marck E, Egwang T, D'Alessandro U. Role of the pfcrt codon 76 mutation as a molecular marker for population-based surveillance of chloroquine (CQ)-resistant Plasmodium falciparum malaria in Ugandan sentinel sites with high CQ resistance. Trans R Soc Trop Med Hyg. 2002; 96(5):551-6. 5. Kyosiimire-Lugemwa J, Nalunkuma-Kazibwe AJ, Mujuzi G, Mulindwa H, Talisuna A, Egwang TG. The Lys-76-Thr mutation in PfCRT and chloroquine resistance in Plasmodium falciparum isolates from Uganda. Trans R Soc Trop Med Hyg. 2002; 96(1):91-5. 14. Rob Newton UVRI (MRC Programme) Cancer epidemiology 1. Waddell KM, Kagame K, Ndamira A, Twinamasiko A, Picton SV, Simmons IG, Revill P, Johnston WT, Newton R. Improving survival of retinoblastoma in Uganda. Br J Ophthalmol. 2015; pii: bjophthalmol-2014-306206. 2. Asiki G, Baisley K, Kamali A, Kaleebu P, Seeley J, Newton R. A prospective study of trends in consumption of cigarettes and alcohol among adults in a rural Ugandan population cohort, 1994-2011. Trop Med Int Health. 2014 Dec 15. doi: 10.1111/tmi.12451. 3. Wakeham K, Johnston WT, Nalwoga A, Webb EL, Mayanja BN, Miley W, Elliott AM, Whitby D, Newton R. Trends in Kaposi's sarcoma-associated Herpesvirus antibodies prior to the development of HIV-associated Kaposi's sarcoma: A nested case-control study. Int J Cancer. 2014;doi: 10.1002/ijc.29329. 4. Waddell KM, Kagame K, Ndamira A, Twinamasiko A, Picton SV, Simmons IG, Johnston WT, Newton R. Clinical features and survival among children with retinoblastoma in Uganda. Br J Ophthalmol. 2014 Sep 12. pii: bjophthalmol-2014-305564. 5. Asiki G, Seeley J, Srey C, Baisley K, Lightfoot T, Archileo K, Agol D, Abaasa A, Wakeham K, Routledge MN, Wild CP, Newton R, Gong YY. A pilot study to evaluate aflatoxin exposure in a rural Ugandan population. Trop Med Int Health. 2014; 19(5):592-9. 15. Jessica Nakiyingi–Miiro UVRI (MRC Programme) Statistics and epidemiology 1. DART Trial Team. Routine versus clinically driven laboratory monitoring of HIV antiretroviral therapy in Africa (DART): a randomization non-inferiority trial. Lancet 2010; 375 (9709):123-131. 2. Shafer LA, Biraro S, Nakiyingi-Miiro J, Kamali A, Ssematimba D, Ouma J, Ojwiya A, Hughes P, van der Paal, L, Whitworth J, Opio A, Grosskurth H. HIV prevalence and incidence are no longer falling in southwest Uganda: evidence from a rural population cohort 1989-2005 AIDS 2008; 22(13):1641-1649. 3. Watera C, Todd J, Mutonyi G, Miiro G, Mpendo J, Hughes P, Nakiyingi-Miiro J, Whitworth J, Grosskurth H. Effects of cotrimoxazole on hematologic parameters in HIV-infected adults in a community-based clinic in Entebbe, Uganda. Journal of Acquired Immune Deficiency Syndrome 2007; 46(3):369-371. 4. Biraro S, Morison L, Nakiyingi-Miiro J, Whitworth JAG, Grosskurth H. The role of vertical transmission and Health Care-related factors in HIV infection of children: A community study in rural Uganda. Journal of Acquired Immune Deficiency Syndrome 2007; 44(2):222-228. 5. Cooke GS, Tosh K, Ramaley PA, Kaleebu P, Zhuang J, Nakiyingi J, Watera C, Gilks CF, French N, Whitworth JA, Hill AV. A Polymorphism that reduces RANTES expression is associated with protection from death in HIV-seropositive Ugandans with advanced disease. The Journal Infectious Diseases 2006; 194:666-669. 16. Sam Biraro UVRI (MRC Programme) HIV epidemiology, NCD epidemiology, HSV epidemiology 1. Kabami J, Turyakira E, Biraro S, Bajunirwe F. Increasing incidence of pregnancy among women receiving HIV care and treatment at a large urban facility in western Uganda. Reprod Health. 2014; 6;11:81. 2. Biraro S, Kamali A, White R, Karabarinde A, Nsiimire Ssendagala J, Grosskurth H, Weiss HA. Effect of HSV-2 on population-level trends in HIV incidence in Uganda between 1990 and 2007. Trop Med Int Health. 2013 Oct;18(10):1257-66. 3. Zhang L, Maher D, Munyagwa M, Kasamba I, Levin J, Biraro S, Grosskurth H. Trends in child mortality: a prospective, population-based cohort study in a rural population in south-west Uganda. Paediatr Int Child Health. 2013; 33(1):23-31. 4. Biraro S, Ruzagira E, Kamali A, Whitworth J, Grosskurth H, Weiss HA. HIV-1 transmission within marriage in rural Uganda: a longitudinal study. PLoS One. 2013;8(2):e55060. 5. Asiki G, Murphy G, Nakiyingi-Miiro J, Seeley J, Nsubuga RN, Karabarinde A, Waswa L, Biraro S, Kasamba I, Pomilla C, Maher D, Young EH, Kamali A, Sandhu MS; GPC team. The general population cohort in rural southwestern Uganda: a platform for communicable and noncommunicable disease studies. Int J Epidemiol. 2013; 42(1):129-41. 17. James Okello Mugisha UVRI (MRC Programme) Gerontology Epidemiology 1. Kuteesa MO, Wright S, Seeley J, Mugisha J, Kinyanda E, Kakembo F, Mwesigwa R, Scholten F. Experiences of HIV-related stigma among HIV-positive older persons in Uganda--a mixed methods analysis. SAHARA J. 2014;11(1):126-37. 2. Mugisha JO, Kuper H, Seeley J. Older people's perception of anemia in rural southwest Uganda. J Aging Health. 2014; 26(2):316-32. 3. Mugisha JO, Baisley K, Asiki G, Seeley J, Kuper H. Prevalence, types, risk factors and clinical correlates of anaemia in older people in a rural Ugandan population. PLoS One. 2013;8(10):e78394. 4. Mayanja BN, Ekoru K, Namugenyi H, Lubega R, Mugisha JO. Patients' worries before starting antiretroviral therapy and their association with treatment adherence and outcomes: a prospective study in rural Uganda, 2004 2009. BMC Res Notes. 2013;6:187. 5. Mugisha J, Scholten F, Owilla S, Naidoo N, Seeley J, Chatterji S, Kowal P,Boerma T. Caregiving responsibilities and burden among older people by HIV status and other determinants in Uganda. AIDS Care. 2013;25(11):1341-8. 18. Josephine Birungi UVRI Entomology, Vector Biology, molecular biology 1. Mulamba C, Riveron JM, Ibrahim SS, Irving H, Barnes KG, Mukwaya LG, Birungi J, Wondji CS. Widespread 2. 3. 4. 5. 19. Godfrey Siu UVRI (MRC Programme) Medical anthropology and sociology (gender, masculinity and health seeking, parenting) pyrethroid and DDT resistance in the major malaria vector Anopheles funestus in East Africa is driven by metabolic resistance mechanisms. PLoS One. 2014;9(10):e110058. Mahamud A, Kamadjeu R, Webeck J, Mbaeyi C, Baranyikwa MT, Birungi J, Nurbile Y, Ehrhardt D, Shukla H, Chatterjee A, Mulugeta A. Effectiveness of oral polio vaccination against paralytic poliomyelitis: a matched case-control study in Somalia. J Infect Dis. 2014;210 Suppl 1:S187-93. Kamadjeu R, Mahamud A, Webeck J, Baranyikwa MT, Chatterjee A, Bile YN, Birungi J, Mbaeyi C, Mulugeta A. Polio outbreak investigation and response in Somalia, 2013. J Infect Dis. 2014 Nov 1;210 Suppl 1:S181-6. Muyanja E, Ssemaganda A, Ngauv P, Cubas R, Perrin H, Srinivasan D, Canderan G,Lawson B, Kopycinski J, Graham AS, Rowe DK, Smith MJ, Isern S, Michael S, Silvestri G, Vanderford TH, Castro E, Pantaleo G, Singer J, Gillmour J, Kiwanuka, Nanvubya A, Schmidt C, Birungi J, Cox J, Haddad EK, Kaleebu P, Fast P, Sekaly RP, Trautmann L. Immune activation alters cellular and humoral responses to yellow fever 17D vaccine. J Clin Invest. 2014 Jul 1;124(7):3147-58. Mulamba C, Irving H, Riveron JM, Mukwaya LG, Birungi J, Wondji CS. Contrasting Plasmodium infection rates and insecticide susceptibility profiles between the sympatric sibling species Anopheles parensis and Anopheles funestus s.s: a potential challenge for malaria vector control in Uganda. Parasit Vectors. 2014;;7:71. 1. Siu GE, Wight D, Seeley J. 'Dented' and 'resuscitated' masculinities: the impact of HIV diagnosis and/or enrolment on antiretroviral treatment on masculine identities in rural eastern Uganda. SAHARA J. 2014;11(1):211-21. 2. Mburu G, Ram M, Siu G, Bitira D, Skovdal M, Holland P. Intersectionality of HIV stigma and masculinity in eastern Uganda: implications for involving men in HIV programmes. BMC Public Health 2014;14:1061. 3. Kawuma R, Bernays S, Siu G, Rhodes T, Seeley J. 'Children will always be children': exploring perceptions and experiences of HIV-positive children who may not take their treatment and why they may not tell. Afr J AIDS Res.2014;13(2):189-95. 4. Siu GE, Seeley J, Wight D. Dividuality, masculine respectability and reputation: how masculinity affects men's uptake of HIV treatment in rural eastern Uganda. Soc Sci Med. 2013;89:45-52. 5. Siu GE, Wight D, Seeley J. How a masculine work ethic and economic circumstances affect uptake of HIV treatment: experiences of men from an artisanal gold mining community in rural eastern Uganda. J Int AIDS Soc. 2012;15 Suppl 1:1-9. 20. Rwamahe Rutakumwa UVRI (MRC Programme) Rural sociology 1. Martin Mbonye, Rwamahe Rutakumwa, Helen Weiss & Janet Seeley. Alcohol consumption and high risk sexual behaviour among female sex workers in Uganda, African Journal of AIDS Research 2014;13:2, 145-151. 2. Rutakumwa, William & Naomi Krogman. Women's Health in Rural Uganda: Problems, Coping Strategies, and Recommendations for Change. Canadian Journal of Nursing Research 2007; 39(3):104-125. 3. Stewart, M., L. Reutter, E. Makwarimba, I. Rootman, D. Williamson, K. Raine, D. Wilson, J. Fast, R. Love, S. McFall, D. Shorten, N. Letourneau, K. Hayward, J. Masuda, & W. Rutakumwa. Determinants of HealthService Use by Low-Income People. Canadian Journal of Nursing Research 2005; 37(3): 104-131. 4. Estabrooks, C.A., W. Rutakumwa, K. O’Leary, J. ProfettoMcGrath, M. Milner, M.J. Levers, & S. Scott-Findlay. Sources of practice knowledge among nurses. Qualitative Health Research 2005; 15(4):460-476. 5. Rutakumwa, William & Naomi Krogman. (2000). Rural Ugandan Women’s Views about their Health and Health Services. WE International 2000: 48/49:28-29. 21. Deogratius Ssemwanga UVRI (MRC Programme) virology 1. Ssemwanga D, Lihana RW, Ugoji C, Abimiku A, Nkengasong J, Dakum P, Ndembi N. Update on HIV-1 Acquired and Transmitted Drug Resistance in Africa. AIDS Rev. 2014;17(1). 2. Redd AD, Ssemwanga D, Vandepitte J, Wendel SK, Ndembi N, Bukenya J, NakubulwaS, Grosskurth H, Parry CM, Martens C, Bruno D, Porcella SF, Quinn TC, Kaleebu P. Rates of HIV-1 superinfection and primary HIV-1 infection are similar in female sex workers in Uganda. AIDS. 2014;28(14):2147-52. 3. Njai HF, Ewings FM, Lyimo E, Foulongne V, Ngerageza D, Mongi A, Ssemwanga D, Andreasen A, Nyombi B, Ao T, Michael D, Urassa M, Todd J, Zaba B, Changalucha J, 4. Hayes R, Kapiga SH. Deciphering the complex distribution of human immunodeficiency virus type 1 subtypes among different cohorts in Northern Tanzania. PLoS One. 2013;8(12):e81848. 5. Ssemwanga D, Nsubuga RN, Mayanja BN, Lyagoba F, Magambo B, Yirrell D, Van der Paal L, Grosskurth H, Kaleebu P. Effect of HIV-1 subtypes on disease progression in rural Uganda: a prospective clinical cohort study. PLoS One. 2013;8(8):e71768. 6. Baalwa J, Wang S, Parrish NF, Decker JM, Keele BF, Learn GH, Yue L, Ruzagira E, Ssemwanga D, Kamali A, Amornkul PN, Price MA, Kappes JC, Karita E, Kaleebu P, Sanders E, Gilmour J, Allen S, Hunter E, Montefiori DC, Haynes BF, Cormier E, Hahn BH, Shaw GM. Molecular identification, cloning and characterization of transmitted/founder HIV-1 subtype A, D and A/D infectiousmolecular clones.Virology 2013;436(1):33-48. KCMUCo 22. Kavishe Reginald. BSc. Educ, MSc, PhD Malaria (drug resistance and genetics) 1. Alifrangis M, Nag S, Schousboe ML, Ishengoma D, Lusingu J, Pota H, Kavishe RA, Pearce R, Ord R, Lynch C, Dejene S, Cox J, Rwakimari J, Minja DT, Lemnge MM, Roper C Independent Origin of Plasmodium falciparum Antifolate Super-Resistance, Uganda, Tanzania, and Ethiopia. Emerg Infect Dis. 2014 Aug;20(8):1280-6. doi: 10.3201/eid2008.131897. 2. Kavishe RA, Paulo P, Kaaya RD, Kalinga A, van Zwetselaar M, Chilongola J, Roper C, Alifrangis M. Surveillance of artemether-lumefantrine associated Plasmodium falciparum multidrug resistance protein-1 gene polymorphisms in Tanzania. Malar J. 2014 Jul 9;13:264. doi: 10.1186/1475-2875-13-264. 3. Matondo SI, Temba GS, Kavishe AA, Kauki JS, Kalinga A, van Zwetselaar M, Reyburn H, Kavishe RA. High levels of sulphadoxine-pyrimethamine resistance Pfdhfr-Pfdhps quintuple mutations: a cross sectional survey of six regions in Tanzania. Malar J. 2014 Apr 21;13:152. doi: 10.1186/1475-2875-13-152. 4. Mohammed A, Ndaro A, Kalinga A, Manjurano A, Mosha JF, Mosha DF, van Zwetselaar M, Koenderink JB, Mosha FW, Alifrangis M, Reyburn H, Roper C, Kavishe RA Trends in chloroquine resistance marker, Pfcrt-K76T mutation ten years after chloroquine withdrawal in Tanzania. Malar J. 2013 Nov 14;12:415. doi: 10.1186/1475-2875-12-415. 5. Protopopoff N, Matowo J, Malima R, Kavishe R, Kaaya R, KCMUCo 23. Prof. F. Mosha BSc. Msc, PhD 1. Malaria (Entomology) and NTDs 2. 3. 4. 5. Wright A, West PA, Kleinschmidt I, Kisinza W, Mosha FW, Rowland M. High level of resistance in the mosquito Anopheles gambiae to pyrethroid insecticides and reduced susceptibility to bendiocarb in north-western Tanzania. Malar J. 2013 May 2;12:149. Doi Matowo J, Jones CM, Kabula B, Ranson H, Steen K, Mosha F, Rowland M, Weetman D. Genetic basis of pyrethroid resistance in a population of Anopheles arabiensis, the primary malaria vector in Lower Moshi, north-eastern Tanzania. Parasit Vectors. 2014 Jun 19;7(1):274. doi: 10.1186/1756-3305-7-274. West PA, Protopopoff N, Wright A, Kivaju Z, Tigererwa R, Mosha FW, Kisinza W, Rowland M, Kleinschmidt I Indoor residual spraying in combination with insecticidetreated nets compared to insecticide-treated nets alone for protection against malaria: a cluster randomised trial in Tanzania. PLoS Med. 2014 Apr 15;11(4):e1001630. doi: 10.1371/journal.pmed.1001630. eCollection 2014 Apr. Kitau J, Oxborough R, Kaye A, Chen-Hussey V, Isaacs E, Matowo J, Kaur H, Magesa SM, Mosha F, Rowland M, Logan J. Laboratory and experimental hut evaluation of a long-lasting insecticide treated blanket for protection against mosquitoes. Parasit Vectors. 2014 Mar 28;7:129. doi: 10.1186/1756-3305-7-129. Mwakitalu ME, Malecela MN, Mosha FW, Simonsen PE. Urban schistosomiasis and soil transmitted helminthiases in young school children in Dar es Salaam and Tanga, Tanzania, after a decade of anthelminthic intervention. Acta Trop. 2014 May;133:35-41. doi: 10.1016/j.actatropica.2014.01.012. Epub 2014 Feb 2. Oxborough RM, Kitau J, Jones R, Feston E, Matowo J, Mosha FW, Rowland MW. Long-lasting control of Anopheles arabiensis by a single spray application of micro-encapsulated pirimiphos-methyl (Actellic® 300 CS). 24. Natacha Protopopoff (Moshi) KCMUCo Malaria - Vector biology KCMUCo 25. Jaffu Chilongola, BVM, MVM, PhD Malaria - Immunology Malar J. 2014 Jan 29;13:37. doi: 10.1186/1475-2875-1337. 1. West PA, Protopopoff N, Wright A, Kivaju Z, Tigererwa R, et al. (2014) Indoor residual spraying in combination with insecticide-treated nets compared to insecticide-treated nets alone for protection against malaria: a cluster randomised trial in Tanzania. PLoS Med 11: e1001630. 2. West PA, Protopopoff N, Rowland M, Cumming E, Rand A, et al. (2013) Malaria risk factors in North West Tanzania: the effect of spraying, nets and wealth. PLoS One 8: e65787. 3. Protopopoff N, Matowo J, Malima R, Kavishe R, Kaaya R, et al. (2013) High level of resistance in the mosquito Anopheles gambiae to pyrethroid insecticides and reduced susceptibility to bendiocarb in north-western Tanzania. Malar J 12: 149. 4. West PA, Protopopoff N, Rowland MW, Kirby MJ, Oxborough RM, et al. (2012) Evaluation of a national universal coverage campaign of long-lasting insecticidal nets in a rural district in north-west Tanzania. Malar J 11: 273. 5. Kilian A, Byamukama W, Pigeon O, Gimnig J, Atieli F, et al. (2011) Evidence for a useful life of more than three years for a polyester-based long-lasting insecticidal mosquito net in Western Uganda. Malar J 10: 299. 1. Kavishe RA, Paulo P, Kaaya RD, Kalinga A, van Zwetselaar M, Chilongola J, Roper C, Alifrangis M. Surveillance of artemether-lumefantrine associated Plasmodium falciparum multidrug resistance protein-1 gene polymorphisms in Tanzania. Malar J. 2014 Jul 9;13:264. doi: 10.1186/1475-2875-13-264. 2. Mosha D, Chilongola J, Ndeserua R, Mwingira F, Genton B. Effectiveness of intermittent preventive treatment with sulfadoxine-pyrimethamine during pregnancy on placental malaria, maternal anaemia and birthweight in areas with high and low malaria transmission intensity in Tanzania. Trop Med Int Health. 2014 Sep;19(9):1048-56. doi: 10.1111/tmi.12349. Epub 2014 Jun 26. 3. Beshir KB, Sutherland CJ, Sawa P, Drakeley CJ, Okell L, Mweresa CK, Omar SA, Shekalaghe SA, Kaur H, Ndaro A, Chilongola J, Schallig HD, Sauerwein RW, Hallett RL, Bousema T. Residual Plasmodium falciparum parasitemia in Kenyan children after artemisinin-combination therapy is associated with increased transmission to mosquitoes and parasite recurrence. J Infect Dis. 2013 Dec 15;208(12):2017-24. doi: 10.1093/infdis/jit431. Epub 2013 Aug 14. 4. Mwanziva CE, Kitau J, Tungu PK, Mweya CN, Mkali H, Ndege CM, Sangas A, Mtabho C, Lukwaro C, Azizi S, Myamba J, Chilongola J, Magesa SM, Shekalaghe S, Mosha FW. Transmission intensity and malaria vector population structure in Magugu, Babati District in Northern Tanzania. Tanzan J Health Res. 2011 Jan;13(1):54-61. 5. Mbugi EV, Meijerink M, Veenemans J, Jeurink PV, McCall M, Olomi RM, Shao JF, Chilongola JO, Verhoef H, Savelkoul HF. Effect of nutrient deficiencies on in vitro Th1 and Th2 cytokine response of peripheral blood mononuclear cells to Plasmodium falciparum infection. 26. Dominic Mosha KCMUCo MD, MPH, PhD Malaria in pregnancy, pharmacovigilance 27. Matthew Kirby (Moshi) malaria control, vector biology KCMUCo 1. Mosha D, Mazuguni F, Mrema S, Abdulla S, Genton B. Medication exposure during pregnancy: a pilot pharmacovigilance system using health and demographic surveillance platform. BMC Pregnancy Childbirth. 2014 Sep 15;14:322. doi: 10.1186/1471-2393-14-322. 2. Mosha D, Chilongola J, Ndeserua R, Mwingira F, Genton B. Effectiveness of intermittent preventive treatment with sulfadoxine-pyrimethamine during pregnancy on placental malaria, maternal anaemia and birthweight in areas with high and low malaria transmission intensity in Tanzania. Trop Med Int Health. 2014 Sep;19(9):1048-56. doi: 10.1111/tmi.12349. Epub 2014 Jun 26. 3. Mosha D, Mazuguni F, Mrema S, Sevene E, Abdulla S, Genton B. Safety of artemether-lumefantrine exposure in first trimester of pregnancy: an observational cohort. Malar J. 2014 May 27;13:197. doi: 10.1186/1475-287513-197. 4. Mosha D, Guidi M, Mwingira F, Abdulla S, Mercier T, Decosterd LA, Csajka C, Genton B. Population pharmacokinetics and clinical response for artemetherlumefantrine in pregnant and nonpregnant women with uncomplicated Plasmodium falciparum malaria in Tanzania. Antimicrob Agents Chemother. 2014 Aug;58(8):4583-92. doi: 10.1128/AAC.02595-14. Epub 2014 May 27. 5. Exavery A, Mrema S, Shamte A, Bietsch K, Mosha D, Mbaruku G, Masanja H. Levels and correlates of nonadherence to WHO recommended inter-birth intervals in Rufiji, Tanzania. BMC Pregnancy Childbirth. 2012 Dec 13;12:152. doi: 10.1186/1471-2393-12-152 1. Z.P.Stewart, R.M.Oxborough, P.K.Tungu, M.J.Kirby, M.W.Rowland & S.R.Irish. 2013. Indoor application of Attractive Toxic Sugar Bait (ATSB) in combination with mosquito nets for control of pyrethroid-resistant 28. Prof. Nyindo Mramba, BVM, MSc, PhD KCMUCo Malaria, Curriculum development mosquitoes. PLoS ONE 8 (12): e84168 2. P.West, N.Protopopoff, M.Rowland, E.Cumming, A.Rand, C.Drakeley, L.A.Wright, Z.Kivaju, M.J.Kirby, F.W.Mosha, W.Kisinza & I.Kleinschmidt. 2013. Malaria risk factors in North West Tanzania: The effect of spraying, nets and wealth. PLoS ONE, 8(6):e65787. 3. M.J.Kirby 2013. House screening. Chapter 7, p117-143. In: Biological and Environmental Control of Disease Vectors, edited by M.M.Cameron and L.M.Lorenz. CABI Publishing, Wallingford, U.K 4. P.Winskill, M.Rowland, G.Mtove, R.C.Malima & M.J.Kirby. 2011. Malaria risk factors in North East Tanzania. Malaria Journal, 10:98. 5. M.J.Kirby, P.Bah, C.Jones, A.H.Kelly, M.Jasseh & S.W.Lindsay. 2010. Social acceptability and durability of two different house screening interventions against exposure to malaria vectors, Plasmodium falciparum infection and anaemia in children in The Gambia, West Africa. American Journal of Tropical Medicine and Hygiene, 83, 965-972 1. Lisasi E, Kulanga A, Muiruri C, Killewo L, Fadhili N, Mimano L, Kapanda G, Tibyampansha D, Ibrahim G, Nyindo M, Mteta K, Kessi E, Ntabaye M, Bartlett J. Modernizing and transforming medical education at the Kilimanjaro Christian medical University College. Acad Med. 2014 Aug;89(8 Suppl):S60-4. doi: 10.1097/ACM.0000000000000327. 2. Nyindo M, Kitau J, Lisasi E, Kapanda G, Matowo J, Francis P, Bartlett J. Introduction of team-based learning (TBL) at Kilimanjaro Christian Medical University College: experience with the ectoparasites module. Med Teach. 2014 Apr;36(4):308-13. doi: 10.3109/0142159X.2013.876490. Epub 2014 Feb 3. 3. Mukama LJ, Moran A, Nyindo M, Philemon R, Msuya L. 4. 5. KCMUCo 29. Prof. Gibson Kibiki, MB ChV, MMED, PhD 1. TB, Infectious Diseases 2. Improved glycemic control and acute complications among children with type 1 diabetes mellitus in Moshi, Tanzania. Pediatr Diabetes. 2013 May;14(3):211-6. doi: 10.1111/pedi.12005. Epub 2013 Jan 25. Kweka EJ, Zhou G, Munga S, Lee MC, Atieli HE, Nyindo M, Githeko AK, Yan G. Anopheline larval habitats seasonality and species distribution: a prerequisite for effective targeted larval habitats control programmes. PLoS One. 2012;7(12):e52084. doi:10.1371/journal.pone.0052084. Epub 2012 Dec 18. Kweka EJ, Zhou G, Beilhe LB, Dixit A, Afrane Y, Gilbreath TM 3rd, Munga S, Nyindo M, Githeko AK, Yan G. Effects of co-habitation between Anopheles gambiae s.s. and Culex quinquefasciatus aquatic stages on life history traits. Parasit Vectors. 2012 Feb 9;5:33. doi: 10.1186/1756 Liu J, Kabir F, Manneh J, Lertsethtakarn P, Begum S, Gratz J, Becker SM, Operario DJ, Taniuchi M, Janaki L, Platts-Mills JA, Haverstick DM, Kabir M, Sobuz SU, Nakjarung K, Sakpaisal P, Silapong S, Bodhidatta L, Qureshi S, Kalam A, Saidi Q, Swai N, Mujaga B, Maro A, Kwambana B, Dione M, Antonio M, Kibiki G, Mason CJ, Haque R, Iqbal N, Zaidi AK, Houpt ER (2014). Development and assessment of molecular diagnostic tests for 15 enteropathogens causing childhood diarrhoea: a multicentre study. Lancet Infect Dis. 2014 Aug;14(8):716-24. doi: 10.1016/S1473-3099(14)70808-4. Epub 2014 JulReddy EA, Njau BN, Morpeth SC, Lancaster KE, Tribble AC, Maro VP, Msuya LJ, Morrissey AB, Kibiki GS, Thielman NM, Cunningham CK, Schimana W, Shao JF, Chow SC, Stout JE, Crump JA, Bartlett JA, Hamilton CD (2014). A randomized controlled trial of standard versus intensified tuberculosis diagnostics on treatment decisions by physicians in Northern Tanzania. BMC Infect Dis. 2014 Feb 20;14:89. doi: 10.1186/1471-233414-89. 3. Mosha JF, Sturrock HJ, Greenwood B, Sutherland CJ, Gadalla NB, Atwal S, Hemelaar S, Brown JM, Drakeley C, Kibiki G, Bousema T, Chandramohan D, Gosling RD (2014). Hot spot or not: a comparison of spatial statistical methods to predict prospective malaria infections. Malar J. 2014 Feb 11;13:53. doi: 10.1186/1475-2875-13-53. 4. Mpagama SG, Nduliso N, Stroup S, Kumburu H, Peloquin CA, Grazt J, Houpt ER, Kibiki GS, Heysell SK (2014). Plasma drug activity in patients on treatment for multidrug-resistant tuberculosis. Antimicrob Agents Chemother. 2014;58(2):782-8. doi: 10.1128/AAC.0154913. Epub 2013 Nov 18. 5. Semvua HH, Kibiki GS, Kisanga ER, Boeree MJ, Burger DM, Aarnoutse R (2014). Pharmacological interactions between rifampicin and antiretroviral drugs: challenges and research priorities for resource-limited settings. Ther Drug Monit. 2014 Jun 17. [Epub ahead of print] KCMUCo 30. Semvua Hadija, B.Pharm, Msc. PhD TB-HIV, Pharmacokinetics, Clinical trials. 1. Semvua HH, Kibiki GS, Kisanga ER, Boeree MJ, Burger DM, Aarnoutse R. Friedrich SO, Rachow A, Saathoff E, Singh K, Mangu CD, Dawson R, Phillips PP, Venter A, Bateson A, Boehme CC, Heinrich N, Hunt RD, Boeree MJ, Zumla A, McHugh TD, Gillespie SH, Diacon AH, Hoelscher M; Pan African Consortium for the Evaluation of Anti-tuberculosis Antibiotics (PanACEA). Assessment of the sensitivity and specificity of Xpert MTB/RIF assay as an early sputum biomarker of response to tuberculosis treatment. Lancet Respir Med. 2013 Aug;1(6):462-70. doi: 10.1016/S2213-2600(13)70119-X. Epub 2013 Jul 1. 2. Tostmann A, Mtabho CM, Semvua HH, van den Boogaard J, Kibiki GS, Boeree MJ, Aarnoutse RE. Pharmacokinetics of first-line tuberculosis drugs in Tanzanian patients. Antimicrob Agents 3. Kayigire XA, Friedrich SO, Venter A, Dawson R, Gillespie SH, Boeree MJ, Heinrich N, Hoelscher M, Diacon AH; Pan African Consortium for the Evaluation of Anti-tuberculosis Antibiotic Direct comparison of Xpert MTB/RIF assay with liquid and solid mycobacterial culture for quantification of early bactericidal activity. J Clin Microbiol. 2013 Jun;51(6):1894-8. doi: 10.1128/JCM.03290-12. Epub 2013 Apr 17. 4. Semvua HH, Mtabho CM, Fillekes Q, van den Boogaard J, Kisonga RM, Mleoh L, Ndaro A, Kisanga ER, van der Ven A, Aarnoutse RE, Kibiki GS, Boeree MJ, Burger DM. Efavirenz, tenofovir and emtricitabine combined with firstline tuberculosis treatment in tuberculosis-HIV-coinfected Tanzanian patients: a pharmacokinetic and safety study. Antivir Ther. 2013;18(1):105-13. doi: 10.3851/IMP2413. Epub 2012 Oct 5. Semvua HH, Kibiki GS, Kisanga ER, Boeree MJ, Burger DM, Aarnoute R. Pharmacological interactions between rifampicin and antiretroviral drugs: challenges and research priorities for resource-limited settings. Ther Drug Monit. 2014 Jun 17. [Epub ahead of print] 31. Stela Mpagama MD, MSc, PhD KCMUCo TB ( MDR – TB) 32. Habib Ramadhani Omari MD, MHS, MPH, PhD KCMUCo TB – HIV Mpagama SG, Ndusilo N, Stroup S, Kumburu H, Peloquin CA, Gratz J, Houpt ER, Kibiki GS, Heysell SK. Plasma drug activity in patients on treatment for multidrug-resistant tuberculosis. Antimicrob Agents Chemother. 2014;58(2):7828. doi: 10.1128/AAC.01549-13. Epub 2013 Nov 18 Mpagama SG, Houpt ER, Stroup S, Kumburu H, Gratz J, Kibiki GS, Heysell SK. Application of quantitative second-line drug susceptibility testing at a multidrug-resistant tuberculosis hospital in Tanzania. BMC Infect Dis. 2013 Sep 14;13:432. doi: 10.1186/1471-2334-13-432. Mpagama SG, Heysell SK, Ndusilo ND, Kumburu HH, Lekule IA, Kisonga RM, Gratz J, Boeree MJ, Houpt ER, Kibiki GS. Diagnosis and interim treatment outcomes from the first cohort of multidrug-resistant tuberculosis patients in Tanzania. PLoS One. 2013 May 13;8(5):e62034. doi: 10.1371/journal.pone.0062034. Print 2013. Mpagama SG, Mtabho C, Mwaigwisya S, Mleoh LJ, Boer IM, Heysell SK, Houpt ER, Kibiki GS. Comparison of overnight pooled and standard sputum collection method for patients with suspected pulmonary tuberculosis in northern Tanzania. Tuberc Res Treat. 2012;2012:128057. doi: 10.1155/2012/128057. Epub 2012 Jan 19. Heysell SK, Mtabho C, Mpagama S, Mwaigwisya S, Pholwat S, Ndusilo N, Gratz J, Aarnoutse RE, Kibiki GS, Houpt ER. Plasma drug activity assay for treatment optimization in tuberculosis patients. Antimicrob Agents Chemother. 2011 Dec;55(12):5819-25. doi: 10.1128/AAC.05561-11. Epub 2011 Oct 3 1. Fiorillo SP, Diefenthal HC, Goodman PC, Ramadhani HO, Njau BN, Morrissey AB, Maro VP, Saganda W, Kinabo GD, Mwako MS, Bartlett JA, Crump JA. Chest radiography for predicting the cause of febrile illness among in patients in Moshi, Tanzania.Clin Radiol. 2013 Oct;68(10):1039-46 KCMUCo 33. Kisanga Elton, B. Pharm, MSc. PhD HIV, PMTCT, Pharmacolodynamics / Kinetics 2. Clifton DC, Ramadhani HO, Msuya LJ, Njau BN, Kinabo GD, Buchanan AM, Crump JA. Predicting mortality for paediatric inpatients where malaria is uncommon. Arch Dis Child. 2012 Oct;97(10):889-94 3. Lofgren SM, Kirsch EJ, Maro VP, Morrissey AB, Msuya LJ, Kinabo GD, Saganda W, Diefenthal HC, Ramadhani HO, Wheat LJ, Crump JA. Histoplasmosis among hospitalized febrile patients in northern Tanzania. Trans R Soc Trop Med Hyg. 2012 Aug;106(8):504-7. 4 Crump, J.A., Tuohy, M.J., Morrissey, A.B., Ramadhani, H.O., Njau, B.N., Maro, V.P., Reller, L.B. & Procop, G.W. 2012, "Performance of Nucleic Acid Amplification following Extraction of 5 Milliliters of Whole Blood for Diagnosis of Mycobacterium tuberculosis Bacteremia", Journal of clinical microbiology, vol. 50, no. 1, pp. 138141 5 Crump JA, Ramadhani HO, Morrissey AB, Saganda W, Mwako MS, Yang LY, Chow SC, Njau BN, Mushi GS, Maro VP, Reller LB, Bartlett JA. Bacteremic disseminated tuberculosis in sub-saharan Africa: a prospective cohort study. Clin Infect Dis. 2012 Jul;55(2):242-50 1. Semvua HH, Kibiki GS, Kisanga ER, Boeree MJ, Burger DM, Aarnoutse R. Pharmacological interactions between rifampicin and antiretroviral drugs: challenges and research priorities for resource-limited settings. Ther Drug Monit. 2014 Jun 17. [Epub ahead of print] 2. Baranyai D, Muro E, Gödtel-Armbrust U, Schirmer MA, Kisanga E, Diczfalusy U, Fillekes Q, Schuurman R, Burger D, Wojnowski L. Reduction of nevirapine-driven HIV mutations by carbamazepine is modulated by CYP3A activity. J Antimicrob Chemother. 2014 Jul;69(7):1933-7. doi: 10.1093/jac/dku086. Epub 2014 Apr 2. 3. George L, Muro EP, Ndaro A, Dolmans W, Burger DM, 4. 5. 1. KCMUCo 34. Eva Muro, B. Pharm, MSc. PhD HIV, PMTCT, Clinical trails 2. 3. Kisanga ER. Nevirapine concentrations in saliva measured by thin layer chromatography and self-reported adherence in patients on antiretroviral therapy at Kilimanjaro Christian medical centre, Tanzania. Ther Drug Monit. 2014 Jun;36(3):366-70. doi: 10.1097/FTD.0000000000000005. Fillekes Q, Muro EP, Chunda C, Aitken S, Kisanga ER, Kankasa C, Thomason MJ, Gibb DM, Walker AS, Burger DM. Effect of 7 days of phenytoin on the pharmacokinetics of and the development of resistance to single-dose nevirapine for perinatal HIV prevention: a randomized pilot trial. J Antimicrob Chemother. 2013 Nov;68(11):2609-15. doi: 10.1093/jac/dkt246. Epub 2013 Jul 17. Gwimile JJ, Shekalaghe SA, Kapanda GN, Kisanga ER. Antibiotic prescribing practice in management of cough and/or diarrhoea in Moshi Municipality, Northern Tanzania: cross-sectional descriptive study. Pan Afr Med J. 2012;12:103. Dorothea Baranyai, Eva Muro, Ute Gödtel-Armbrust, Markus A Schirmer, Elton Kisanga, Ulf Diczfalusy, Quirine Fillekes, Rob Schuurman, David Burger, Leszek Wojnowski.,Reduction of nevirapine-driven HIV mutations by carbamazepine is modulated by CYP3A activity. Journal of Antimicrobial Chemotherapy. 2014 Jul; 69(7):1933-7 George L, Muro EP, Ndaro A, Dolmans W, Burger DM, Kisanga ER.Nevirapine Concentrations in Saliva Measured by Thin Layer Chromatography and SelfReported Adherence in Patients on Antiretroviral Therapy at Kilimanjaro Christian Medical Centre, Tanzania. Ther Drug Monit. 2014 June; 36(3):366–370 Quirine Fillekes, Eva Muro, Catherine Chunda, Margaret Thomason, Susan Aitken, Elton Kisanga, Chipepo Kankasa, Diana Gibb, A. Sarah Walker, David Burger, Effect of Seven Days Phenytoin on Pharmacokinetics of and Resistance to Single-Dose Nevirapine for Perinatal HIV Prevention: a Randomized Pilot Study. Journal of Antimicrobial Chemotherapy 2013; 68(11):2609–1 4. Eva P. Muro, Quirine Fillekes,Elton R. Kisanga, Rafaëlla L’homme, Susan C. Aitken, Godfrey Mariki,k Andre J. A. M. Van der Ven, Wil Dolmans, Rob Schuurman, A. Sarah WalkerDiana M. Gibb, David M. Burger, Intrapartum Single-Dose Carbamazepine Reduces Nevirapine Levels Faster and May Decrease Resistance After a Single Dose of Nevirapine for Perinatal HIV Prevention. J Acquir Immune Defic Syndr 2012;59:266–273 5. Rafae¨ lla F. A. L’homme, Eva P. Muro, Jacqueline A. H. Droste, Liselotte R. Wolters, Noor W. J. van EwijkBeneken Kolmer, Werner Schimana, David M. Burger. Therapeutic Drug Monitoring of Nevirapine in ResourceLimited Settings., Clinical Infectious Diseases 2008; 47:1339–44 KCMUCo 35. Ireen Kiwelu, BSc. MSc, MPhil, PhD HIV (Molecular characterization of HIV-1 viruses and drug resistance mutations) 1. Ireen E. Kiwelu, Vladmir Novitsky, Elimsaada Kituma, Lauren Margolin, Jeannie Baca, Rachel Manongi, Noel Sam, John Shao, Mary F. McLane, Saidi H. Kapiga and Max Essex. HIV-1 pol divesity among female bar and hotel workers in Northern Tanzania. PLOS ONE 2014; Jul 08; 9 (7):e102258 2. Ao TT, Sam N, Kiwelu I, Mahal A, Subramanian SV, Wyshak G, Kapiga S. Risk factors of alcohol problem drinking among bar/hotel workers in Moshi, Tanzania: a multi-level analysis. AIDS Behav. 2011 Feb: 15 (2):330-9 3. Ireen E. Kiwelu, Vladmir Novitsky, Lauren Margolin, Jeannie Baca, Rachel Manongi, Noel Sam, John Shao, Mary F. McLane, Saidi H. Kapiga and Max Essex. HIV1 subtypes and recombinants in Northern Tanzania: distribution of viral quasispecies. PLoS ONE 2012; 7, e47605. 4. Ireen E. Kiwelu, Vladmir Novitsky, Lauren Margolin, Jeannie Baca, Rachel Manongi, Noel Sam, John Shao, Mary F. McLane, Saidi H. Kapiga and Max Essex. Frequent intra-subtype recombination among HIV-1 circulating in Tanzania. PLoS ONE 2013; 8, e7113Nel AM, Coplan P, van de Wijgert JH, Kapiga SH, von Mollendorf C, Geubbels E, Vyankandondera J, Rees HV, Masenga G, Kiwelu I, Moyes J, Smythe SC. Safety, tolerability, and systemic absorption of dapivirine vaginal microbicide gel in healthy, HIV-negative women. AIDS. 2009 Jul 31;23(12):1531-8. doi: 10.1097/QAD.0b013e32832c413d. 36. Kinabo Grace, MD, M.MED, PhD KCMUCo HIV, Paediatric Infectious Diseases. 1. Grace D. Kinabo, Mirte Sprengers, Levina J. Msuya, Aisa M. Shayo, MD, Henri van Asten, Wil M.V. olmans, Andre J.A.M. van der Ven, and Adilia Warris, Prevalence of Lipodystrophy in HIV-infected Children in Tanzania on Highly Active Antiretroviral Therapy Pediatr Infect Dis J 2013;32: 39–44 2. G. D. Kinabo, A. van der Ven, L. J. Msuya, A. M. Shayo, W. Schimana1, A. Ndaro3, H. A. G. H. van Asten4,,W. M. V. Dolmans4,, A. Warris5,6 and P. W. M. Hermans, Dynamics of nasopharyngeal bacterial colonisation in HIV-exposed young infants in Tanzania Tropical Medicine and International Health doi:10.1111/tmi.12057volume 18 no 3 pp 286–295 march 2013 3. John ACrump,Habib Ramadhani, Anne Morrissey, Levina Msuya, Lan-Yang, Schein-Chung, Susan Morpreth, Hugh Reyburn, Boniface Njau, Andrea Shaw, Helmet Diefental, John Bartlett, John Shao, Werner Schimana, Collen Cunningham and Grace Kinabo. 4. 5. 37. Baltazar Nyombi DiP MLT,M Phil, PhD KCMUCo HIV (Molecular characterization of HIV-1 viruses and drug resistance mutations) 1. 2. Invasive bacterial and fungal infections among hospitalized HIV- infected and HIV-uninfected children and infants in northern Tanzania. Tropical Medicine and International Health: doi 10.111/j 1365-3156.2011 Holly M.Bigs, Rebecca Leste, Behzad Nadjjm George Mtove, Jim E Todd, Grace Kinabo, Rune Philemon, Ben Amos, Anne B.. Morissey, Hugh Reyburn, and John A Crump Invasive Salmonella Infections in Areas of High and Low Malaria Transmission Intensity in Tanzania Clin Infect Dis. (2013) doi: 10.1093/cid/cit798 Malavika Prabhu,1 William L. Nicholson,2 Aubree J. Roche,2 Gilbert J. Kersh,2 Kelly A. Fitzpatrick,Lindsay D. Oliver, Robert F. Massung, Anne B. Morrissey,1 John A. Bartlett,1,3 Jecinta J. Onyango,Venance P. Maro, Grace D. Kinabo,4,5 Wilbrod Saganda,6 and John A. Crump Q Fever, Spotted Fever Group, and Typhus Group Rickettsioses Among Hospitalized Febrile Patients in Northern Tanzania Clinical Infectious Diseases 2011;53(4):e8–e15 Tann C, Nakakeeto M, Hagmann C, Webb E, Nyombi N, Harvey-Jones K, Namiiro F, Burgoine K, Elliott A, Kurinczuk J, Robertson Nj, Cowan F. 8.10 Cranial ultrasound findings suggest that the injury pathway may begin many hours before delivery in encephalopathic infants in Uganda. Arch Dis Child Fetal Neonatal Ed. 2014 Jun;99 Suppl 1:A14-5. doi: 10.1136/archdischild2014-306576.39. Tann CJ, Nkurunziza P, Nakakeeto M, Oweka J, Kurinczuk JJ, Were J, Nyombi N, Hughes P, Willey BA, Elliott AM, Robertson NJ, Klein N, Harris KA. Prevalence of bloodstream pathogens is higher in neonatal encephalopathy cases vs. controls using a novel panel of real-time PCR assays. PLoS One. 2014 May 16;9(5):e97259. doi: 10.1371/journal.pone.0097259. 38. Levina Msuya MD, M MED, MSc in Endocrinology KCMUCo HIV in children and NCDs eCollection 2014. 3. Shao ER, Kifaro EG, Chilumba IB, Nyombi BM, Moyo S, Gaseitsiwe S, Musonda R, Johannessen A, Kibiki G, Essex M. HIV-1 drug mutations in children from northern Tanzania. J Antimicrob Chemother. 2014 Jul;69(7):192832. doi: 10.1093/jac/dku087. Epub 2014 Apr 11. 4. Buchanan AM, Dow DE, Massambu CG, Nyombi B, Shayo A, Musoke R, Feng S, Bartlett JA, Cunningham CK, Schimana W. Progress in the prevention of mother to child transmission of HIV in three regions of Tanzania: a retrospective analysis. PLoS One. 2014 Feb 13;9(2):e88679. doi: 10.1371/journal.pone.0088679. eCollection 2014. 5. Njai HF, Ewings FM, Lyimo E, Foulongne V, Ngerageza D, Mongi A, Ssemwanga D, Andreasen A, Nyombi B, Ao T, Michael D, Urassa M, Todd J, Zaba B, Changalucha J, Hayes R, Kapiga SH. Deciphering the complex distribution of human immunodeficiency virus type 1 subtypes among different cohorts in Northern Tanzania. PLoS One. 2013 Dec 11;8(12):e81848. doi: 10.1371/journal.pone.0081848. eCollection 2013. 1. Mukama LJ, Moran A, Nyindo M, Philemon R, Msuya L. Improved glycemic control and acute complications among children with type 1 diabetes mellitus in Moshi, Tanzania. Pediatr Diabetes. 2013 May;14(3):211-6. doi: 10.1111/pedi.12005. Epub 2013 Jan 25. 2. Neuhann HF, Warter-Neuhann C, Lyaruu I, Msuya L. Diabetes care in Kilimanjaro region: clinical presentation and problems of patients of the diabetes clinic at the regional referral hospital-an inventory before structured intervention. Diabet Med. 2002 Jun;19(6):509-13. 3. Nsheha AH, Dow DE, Kapanda GE, Hamel BC, Msuya LJ. Adherence to antiretroviral therapy among HIVinfected children receiving care at Kilimanjaro Christian 4. 5. 39. Manongi Rachel. MD, MPhil. PhD KCMUCo HIV /Neonatal Health / Health systems 1. 2. 3. Medical Centre (KCMC), Northern Tanzania: A crosssectional analytical study. Pan Afr Med J. 2014 Mar 28;17:238. doi: 10.11604/pamj.2014.17.238.2280. eCollection 2014. Mumburi LP, Hamel BC, Philemon RN, Kapanda GN, Msuya LJ. Factors associated with HIV-status disclosure to HIV-infected children receiving care at Kilimanjaro Christian Medical Centre in Moshi, Tanzania. Pan Afr Med J. 2014 May 15;18:50. doi: 10.11604/pamj.2014.18.50.2307. eCollection 2014. Gray KD, Cunningham CK, Clifton DC, Afwamba IA, Mushi GS, Msuya LJ, Crump JA, Buchanan AM. Prevalence of mycobacteremia among HIV-infected infants and children in northern Tanzania. Pediatr Infect Dis J. 2013 Jul;32(7):754-6. doi: 10.1097/INF.0b013e318286957f. Corneli AL, Deese J, Wang M, Taylor D, Ahmed K, Agot K, Lombaard J, Manongi R, Kapiga S, Kashuba A, Van Damme L; FEM-PrEP Study Group. FEM-PrEP: adherence patterns and factors associated with adherence to a daily oral study product for pre-exposure prophylaxis. J Acquir Immune Defic Syndr. 2014 Jul 1;66(3):324-31. doi: 10.1097/QAI.0000000000000158 Manongi R, Mushi D, Kessy J, Salome S, Njau B. Does training on performance based financing make a difference in performance and quality of health care delivery? Health care provider's perspective in Rungwe Tanzania. BMC Health Serv Res. 2014 Apr 4;14:154. doi: 10.1186/1472-6963-14-154. Mbwele B, Ide N, Mrema J, Ward Sarah A, Melnick J, Manongi R. Learning from health care workers' opinions for improving quality of neonatal health care in kilimanjaro region, northeast Tanzania. Ann Med Health Sci Res. 2014 Jan;4(1):105-14. doi: 10.4103/2141- 40. Jim Todd (Moshi) KCMUCo epidemiology and control of HIV and STI, biostatistics and research methodology 9248.126614. 4. Mujugira A, Magaret AS, Celum C, Baeten JM, Lingappa JR, Morrow RA, Fife KH, Delany-Moretlwe S, de Bruyn G, Bukusi EA, Karita E, Kapiga S, Corey L, Wald A; Partners in Prevention HSV/HIV Transmission Study TeamDaily acyclovir to decrease herpes simplex virus type 2 (HSV-2) transmission from HSV-2/HIV-1 coinfected persons: a randomized controlled trial. J Infect Dis. 2013 Nov 1;208(9):1366-74. doi: 10.1093/infdis/jit333. Epub 2013 Jul 30. 5. Mbwele B, Ide NL, Reddy E, Ward SA, Melnick JA, Masokoto FA, Manongi R. Quality of neonatal healthcare in Kilimanjaro region, northeast Tanzania: learning from mothers' experiences. BMC Pediatr. 2013 May 3;13:68. doi: 10.1186/1471-2431-13-68. 1. Mwendo EM, Mtuy TB, Renju J, Rutherford GW, Nondi J, Sichalwe AW, Todd J. Effectiveness of prevention of mother-to-child HIV transmission programmes in Kilimanjaro region, northern Tanzania. Trop Med Int Health. 2014 Mar;19(3):267-74 2. Todd J, Heyderman RS, Musoke P, Peto T. When enough is enough: how the decision was made to stop the FEAST trial: data and safety monitoring in an African trial of Fluid Expansion As Supportive Therapy (FEAST) for critically ill children. Trials. 2013 Mar 26;14:85. PMID:23531379 3. Todd J, Riedner G, Maboko L, et al. Effect of genital herpes on cervicovaginal HIV shedding in women coinfected with HIV AND HSV-2 in Tanzania. PLoS One. 2013;8(3):e59037. PMID:23516595 4. Todd J, Wringe A, Floyd S, Zaba B. Antiretroviral therapy in sub-Saharan Africa: evidence about need, uptake and impact from community-based cohort studies. Trop Med Int Health. 2012 Aug;17(8):e1-2. PMID:22943373 5. Todd J, Glynn JR, Marston M, et al. Time from HIV KCMUCo 41. Prof. F. Mosha BSc. Msc, PhD Malaria (Entomology) and NTDs seroconversion to death: a collaborative analysis of eight studies in six low and middle-income countries before highly active antiretroviral therapy. AIDS 2007 Nov; 21(Suppl 6):S55-S63. 1. Matowo J, Jones CM, Kabula B, Ranson H, Steen K, Mosha F, Rowland M, Weetman D. Genetic basis of pyrethroid resistance in a population of Anopheles arabiensis, the primary malaria vector in Lower Moshi, north-eastern Tanzania. Parasit Vectors. 2014 Jun 19;7(1):274. doi: 10.1186/1756-3305-7-274. 2. West PA, Protopopoff N, Wright A, Kivaju Z, Tigererwa R, Mosha FW, Kisinza W, Rowland M, Kleinschmidt I Indoor residual spraying in combination with insecticidetreated nets compared to insecticide-treated nets alone for protection against malaria: a cluster randomised trial in Tanzania. PLoS Med. 2014 Apr 15;11(4):e1001630. doi: 10.1371/journal.pmed.1001630. eCollection 2014 Apr. 3. Kitau J, Oxborough R, Kaye A, Chen-Hussey V, Isaacs E, Matowo J, Kaur H, Magesa SM, Mosha F, Rowland M, Logan J. Laboratory and experimental hut evaluation of a long-lasting insecticide treated blanket for protection against mosquitoes. Parasit Vectors. 2014 Mar 28;7:129. doi: 10.1186/1756-3305-7-129. 4. Mwakitalu ME, Malecela MN, Mosha FW, Simonsen PE. Urban schistosomiasis and soil transmitted helminthiases in young school children in Dar es Salaam and Tanga, Tanzania, after a decade of anthelminthic intervention. Acta Trop. 2014 May;133:35-41. doi: 10.1016/j.actatropica.2014.01.012. Epub 2014 Feb 2. 5. Oxborough RM, Kitau J, Jones R, Feston E, Matowo J, Mosha FW, Rowland MW. Long-lasting control of Anopheles arabiensis by a single spray application of micro-encapsulated pirimiphos-methyl (Actellic® 300 CS). Malar J. 2014 Jan 29;13:37. doi: 10.1186/1475-2875-13- 42. Mushi Declare, BA, Ma, PhD KCMUCo NCDs (Dementia), Social Studies 43. Levina Msuya MD, M MED, MSc in Endocrinology KCMUCo NCDs (Diabetes in children/ HIV) 37. 1. Manongi R, Mushi D, Kessy J, Salome S, Njau B. Does training on performance based financing make a difference in performance and quality of health care delivery? Health care provider's perspective in Rungwe Tanzania. BMC Health Serv Res. 2014 Apr 4;14:154. doi: 10.1186/1472-6963-14-154. 2. Mushi D, Rongai A, Paddick SM, Dotchin C, Mtuya C, Walker R. Social representation and practices related to dementia in Hai District of Tanzania. BMC Public Health. 2014 Mar 19;14:260. doi: 10.1186/1471-2458-14-260. 3. Marwa B, Njau B, Kessy J, Mushi D. Feasibility of introducing compulsory community health fund in low resource countries: views from the communities in Liwale district of Tanzania. BMC Health Serv Res. 2013 Aug 8;13:298. doi: 10.1186/1472-6963-13-298. 4. Lyimo RA, de Bruin M, van den Boogaard J, Hospers HJ, van der Ven A, Mushi D. Determinants of antiretroviral therapy adherence in northern Tanzania: a comprehensive picture from the patient perspective. BMC Public Health. 2012 Aug 30;12:716. doi: 10.1186/1471-2458-12-716. 5. Lyimo RA, van den Boogaard J, Msoka E, Hospers HJ, van der Ven A, Mushi D, de Bruin M. Measuring adherence to antiretroviral therapy in northern Tanzania: feasibility and acceptability of the Medication Event Monitoring System. BMC Public Health. 2011 Feb 9;11:92. doi: 10.1186/1471-2458-11-92. 1. Mukama LJ, Moran A, Nyindo M, Philemon R, Msuya L. Improved glycemic control and acute complications among children with type 1 diabetes mellitus in Moshi, Tanzania. Pediatr Diabetes. 2013 May;14(3):211-6. doi: 10.1111/pedi.12005. Epub 2013 Jan 25. 2. Neuhann HF, Warter-Neuhann C, Lyaruu I, Msuya L. 44. Jenny Renju (Moshi) KCMUCo implementation research, reproductive health, NCDs and health systems Diabetes care in Kilimanjaro region: clinical presentation and problems of patients of the diabetes clinic at the regional referral hospital-an inventory before structured intervention. Diabet Med. 2002 Jun;19(6):509-13. 3. Nsheha AH, Dow DE, Kapanda GE, Hamel BC, Msuya LJ. 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Ueno E, Adegoke AA, Masenga G, Fimbo J, Msuya SE. Skilled Birth Attendants in Tanzania: A Descriptive Diploma in RH 2. 3. 4. 5. 49. Manongi Rachel. MD, MPhil. PhD KCMUCo Neonatal Health /HIV / Health systems 1. 2. Study of Cadres and Emergency Obstetric Care Signal Functions Performed. Matern Child Health J. 2014 May 4. [Epub ahead of print] Watt MH, Wilson SM, Joseph M, Masenga G, MacFarlane JC, Oneko O, Sikkema KJ. Religious coping among women with obstetric fistula in Tanzania. Glob Public Health. 2014;9(5):516-27. doi: 10.1080/17441692.2014.903988. Epub 2014 Apr 15. Mahande MJ, Daltveit AK, Mmbaga BT, Masenga G, Obure J, Manongi R, Lie RT. Recurrence of preeclampsia in northern Tanzania: a registry-based cohort study. PLoS One. 2013 Nov 1;8(11):e79116. doi: 10.1371/journal.pone.0079116. eCollection 2013. Montgomery ET, van der Straten A, Cheng H, Wegner L, Masenga G, von Mollendorf C, Bekker L, Ganesh S, Young K, Romano J, Nel A, Woodsong C. 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Heiner Grosskurth National Institute for Medical Research/Mwanza Intervention Trials Unit IDs (HIV and other STIs) and NCDs (e.g. CVD, diabetes) 5. Peck R, Mghamba J, Vanobberghen F, Kavishe B, Rugarabamu V, Smeeth L, Hayes R, Grosskurth H, Kapiga S. Preparedness of Tanzanian health facilities for outpatient primary care of hypertension and diabetes: a cross-sectional survey. Lancet Glob Health 2014;2(5):e285-e292. 1. Woodd S, Grosskurth H, Levin J, Amuron B, Namara G, Coutinho A, Jaffar S: Home-based versus clinic-based care for patients starting antiretroviral therapy with low CD4 counts in Uganda: findings from a clusterrandomised trial. AIDS. 2014;28(4):569-76. doi: 10.1097/ PMID: 24468997 2. Munderi P, Grosskurth H, Droti B, Ross DA. What are the essential components of HIV treatment and care services in low and middle-income countries? An overview by settings and levels of the health care system AIDS 2012 Dec;26 Suppl 2:S97-S103. doi: 10.1097/QAD.0b013e32835bdde6. 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George PrayGod National Institute for Medical Research/Mwanza Intervention Trials Unit IDs (TB and HIV) and NCDs, (diabetes mellitus, and other chronic noncommunicable diseases) 1. Immune Defic Syndr. 2013 Jan 1;62(1):119-26. doi: 10.1097/QAI.0b013e3182777167. PMID: 23075920 Walker J, Holm Hansen C, Martin P, Symeonides S, Ramessur R, Murray G, Sharpe M. 2014, " Prevalence, associations and adequacy of treatment of major depression in 21,151 cancer outpatients: a cross-sectional analysis of routinely collected clinical data", Lancet Psychiatry, 2014 Aug 28. DOI: 10.1016/S22150366(14)70313-X. Sharpe M, Walker J, Holm Hansen C, Martin P, Symeonides S, Gourley C, Wall L, Weller D, Murray G. 2014, "Integrated collaborative care for comorbid major depression in cancer patients (SMaRT Oncology-2): a multicentre randomised controlled effectiveness trial", The Lancet, 2014 Aug 28. DOI: doi:10.1016/S01406736(14)61231-9. Holm Hansen C, Walker J, Thekkumpurath P, Kleiboer A, Beale C, Sawhney A, Murray G, Sharpe M. 2013, 4. “Screening medical patients for distress and depression: does measurement in the clinic prior to the consultation overestimate distress measured at home?”, Psychological Medicine, vol. 43, pp. 2121–2128 Holm Hansen C, Weir C, Warner P, Critchley H. 2013, “An integrated approach to the development of a Bayesian response-adaptive dose-finding study using SAS and WinBUGS”, Trials, vol. 14 (Suppl 1):O74. Holm Hansen C, Murray G, Sharpe M. 2013, “Using evidence from observational healthcare data to inform a trial design”, Trials, vol. 14 (Suppl 1):O1. Jeremiah K, Denti P, Chigutsa E, Faurholt-Jepsen D, PrayGod G, Range N, Castel S, Wiesner L, Hagen CM, Christiansen M, Changalucha J, McIlleron H, Friis H, Andersen AB: Nutritional supplementation increases rifampin exposure among tuberculosis patients coinfected 2. 3. 4. 5. 76. Kidola Jeremiah National Institute for Medical Research/Mwanza IDs (TB and HIV) and NCDs (Diabetes). 1. with HIV. Antimicrob Agents Chemother 2014;58:34683474. Faurholt-Jepsen D, Range N, PrayGod G, Jeremiah K, Faurholt-Jepsen M, Aabye MG, Changalucha J, Christensen DL, Grewal HM, Martinussen T, Krarup H, Witte DR, Andersen AB, Friis H: Diabetes is a strong predictor of mortality during tuberculosis treatment: A prospective cohort study among tuberculosis patients from Mwanza, Tanzania. Trop Med Int Health 2013;18:822-829. PrayGod G, Range N, Faurholt-Jepsen D, Jeremiah K, Faurholt-Jepsen M, Aabye MG, Jensen L, Jensen AV, Grewal HM, Magnussen P, Changalucha J, Andersen AB, Friis H: The effect of energy-protein supplementation on weight, body composition and handgrip strength among pulmonary tuberculosis hiv-co-infected patients: Randomised controlled trial in Mwanza, Tanzania. Br J Nutr 2012;107:263-271. 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Increased level of acute phase reactants in patients infected with modern Mycobacterium tuberculosis genotypes in Mwanza, Tanzania.BMC Infect Dis. 2014 Jun 5;14:309. doi: 10.1186/1471-2334-14-309. Jeremiah K, Denti P, Chigutsa E, Faurholt-Jepsen D, PrayGod G, Range N, Castel S, Wiesner L, Hagen CM, Christiansen M, Changalucha J, McIlleron H, Friis H, Andersen AB. Nutritional Supplementation Increases Rifampin Exposure among Tuberculosis Patients Coinfected with HIV.Antimicrob Agents Chemother. 2014 Jun;58(6):3468-74. doi: 10.1128/AAC.02307-13. Epub 2014 Apr 7. Faurholt-Jepsen D, Aabye MG, Jensen AV, Range N, Praygod G, Jeremiah K, Changalucha J, Faurholt-Jepsen M, Jensen L, Jensen SM, Krarup H, Ravn P, Friis H, Andersen AB. Diabetes is associated with lower tuberculosis antigen-specific interferon gamma release in Tanzanian tuberculosis patients and non-tuberculosis controls.Scand J Infect Dis. 2014 May;46(5):384-91. doi: 10.3109/00365548.2014.885657. Epub 2014 Mar 12. Chantler T, Cheah PY, Miiro G, Hantrakum V, Nanvubya A, Ayuo E, Kivaya E, Kidola J, Kaleebu P, Parker M, Njuguna P, Ashley E, Guerin PJ, Lang T. International health research monitoring: exploring a scientific and a cooperative approach using participatory action research.BMJ Open. 2014 Feb 17;4(2):e004104. doi: 10.1136/bmjopen-2013 Faurholt-Jepsen D, Range N, Praygod G, Jeremiah K, Faurholt-Jepsen M, Aabye MG, Changalucha J, Ritz C, Christensen DL, Jørgensen ME, Andersen AB, Friis H. The association between conventional risk factors and diabetes is weak among urban Tanzanians. Diabetes Care. 2014 Jan;37(1):e5-6. doi: 10.2337/dc13-1905 77. Safari Kinung’hi National Institute for Medical Research/Mwanza Intervention Trials Unit NTDs (Schistosomiasis and other neglected tropical diseases) and IDS (malaria and HIV) 1. Sarah Pedersen., Amanda Wilkinson., Aura Andreasen., David Warhurst., Safari Kinung’hi., Mark Urassa., Denna Michael., John Chamgalucha., Jim Todd., Joann M McDermid (2014). Cryptosporidium Prevalence and Risk Factors among Mothers and their Infants 0 to 6 Months in Rural and Semi-Rural Northwest Tanzania: A Prospective Cohort Study. PLOS Neglected Tropical Diseases. In press. 2. Teckla Angelo., Francis Shahada., Ayubu Kassuku., Humphrey Mazigo., Curtis Kariuki., Anouk Gouvras., David Rollinson., Safari Kinung’hi (2014). Population Abundance and Disease Transmission Potential of Snail intermediate hosts of Human Schistosomiasis in Fishing Communities of Mwanza region, North-western, Tanzania. International Journal of science and Research. Volume 3 Issue 8, August 2014, 1230-1236. 3. Safari M. Kinung’hi., Pascal Magnussen., Godfrey M. Kaatano., Coleman Kishamawe., Birgitte J. Vennervald (2014). Malaria and Helminth Co-Infections in School and Preschool Children: A Cross-Sectional Study in Magu District, North-Western Tanzania. PLoS ONE 9 (1): e86510. 4. Mashauri, Fabian; Kinung’hi, Safari; Kaatano, Godfrey; Magesa, Stephen; Kishamawe, Coleman; Mwanga, Joseph; Nnko, Soori; Malima, Robert; Mero, Chacha; Mboera, Leonard (2013). Impact of indoor residual spraying of lambdacyhalothrin on malaria prevalence and anemia in an epidemic-prone district of Muleba, NorthWestern Tanzania. Am. J. Trop. Med. Hyg. 88 (5), 841849. 5. Humphrey D. Mazigo., Fred Nuwaha., Safari M. Kinung’hi., Domenica Morona., Jorg Heukelbach., David W. Dunne (2013). Epidemiology and interactions of Human Immunodeficiency Virus-1 Schistosoma mansoni in Sub-Saharan Africa. Infectious Diseases of Poverty, 2013, 2:2. 78. Alfaxard Manjurano National Institute for Medical Research/Mwanza Intervention Trials Unit IDs (malaria) 1. Saguti, F, Balthazary, S, Manjurano, A, Max, R, Tenu, F, Francis, F, Shekalaghe, SA and Kavishe, RA, ' Relationship between alpha+-thalassaemia and glutathione-S-transferases polymorphisms in children with severe malaria in Tanzania ', Tanzania Journal of Health Research , 15(2) 2013. 2. Sawa, P, Shekalaghe, SA, Drakeley, CJ, Sutherland, CJ, Mweresa, CK, Baidjoe, AY, Manjurano, A, Kavishe, RA, Beshir, KB, Yussuf, RU, Omar,SA, Hermsen, CC, Okell, L, Schallig, HDFH, Sauerwein, RW, Hallett, RL, Bousema, T, ' Malaria transmission after artemetherlumefantrine and dihydroartemisinin-piperaquine: a randomized trial', J Infect Dis,2013; 207(11): 1637-1645. 3. Manjurano A, Clark TG, Nadjm B, Mtove G, Wangai H, Sepulveda N, Campino SG, Maxwell CC, Olomi R, Rockett KR, Jeffreys A, MalariaGen consortium, Riley EM, Reyburn H, Drakeley C, ' Candidate human genetic polymorphisms and severe malaria in a Tanzanian population', PLos One, 7 (2012), e47463. 4. Manjurano A, Okell L, Lukindo T, Reyburn H, Olomi R, Roper C, Clark TG, Joseph S, Riley E and Drakeley C, 'Association of submicroscopic malaria parasites carriage with transmission intensity in Northeastern Tanzania', Malaria Journal, 10:370 (2011). 5. Mtove G , Hendriksen I, Amos B, Mrema H, Mandia V, Manjurano A, Muro F, Sykes A, Hildenwall H, Whitty CJM and Reyburn H, 'Antimalarial treatment directed by rapid diagnostic test results in children living in a malariaendemic area of Tanzania', Malaria Journal, 10:290 (2011). 79. Jackline Mosha National Institute for Medical Research/Mwanza Intervention Trials Unit IDs (malaria) and Reproductive health 80. Mark S. Urassa National Institute for Medical Research/Mwanza IDs (HIV) and Reproductive health 1. Mosha JF, Sturrock HJ, Greenwood B, Sutherland CJ, Gadalla NB, Atwal S, Hemelaar S, Brown JM, Drakeley C, Kibiki G, Bousema T, Chandramohan D, Gosling RD. “Hot spot or not: a comparison of spatial statistical methods to predict prospective malaria infections.” Malar J. 2014 Feb 11;13(1):53. doi: 10.1186/1475-2875-13-53. PMID: 24517452 2. Mosha JF, Sturrock HJ, Greenhouse B, Greenwood B, Sutherland CJ, Gadalla N, Atwal S, Drakeley C, Kibiki G, Bousema T, Chandramohan D, Gosling R. “Epidemiology of subpatent Plasmodium falciparum infection: implications for detection of hotspots with imperfect diagnostics.” Malar J. 2013 Jul 1;12:221. doi: 10.1186/1475-2875-12-221 3. Sweeney S, Mosha JF, Terris-Prestholt F, Sollis KA, Kelly H, Changalucha J, Peeling RW. “The costs of accessible quality assured syphilis diagnostics: informing quality systems for rapid syphilis tests in a Tanzanian setting.” Health Policy Plan. 2013 Jul 27 4. Mohammed A, Ndaro A, Kalinga A, Manjurano A, Mosha JF, Mosha DF, van Zwetselaar M, Koenderink JB, Mosha FW, Alifrangis M, Reyburn H, Roper C, Kavishe RA. “Trends in chloroquine resistance marker, Pfcrt-K76T mutation ten years after chloroquine withdrawal in Tanzania.” Malar J. 2013 Nov 14;12:415. doi: 10.1186/1475-2875-12-415. 5. Gosling RD, Okell L, Mosha J, Chandramohan D. “The role of antimalarial treatment in the elimination of malaria.” Clin Microbiol Infect. 2011 Nov;17(11):1617-23. doi: 10.1111/j.1469-0691.2011.03660.x. Epub 2011 Sep 26. Review. 1. Pieter W Smit, Thomas van der Vlis, David Mabey, John Changalucha, Julius Mngara, Benjamin D Clark, Aura Andreasen, Jim Todd, Mark Urassa, Basia Zaba and Intervention Trials Unit 2. 3. 4. 5. 81. Joseph R. Mwanga National Institute for Medical Research/Mwanza Intervention Trials Unit NTDs (Schistosomiasis) and IDs (HIV and malaria) and Reproductive health 1. 2. Rosanna W Peeling. The development and validation of dried blood spots for external quality assurance of syphilis serology. BMC Infectious Diseases 2013, 13:102 doi:10.1186/1471-2334-13-102. Raphael Isingo, Alison Wringe, Jim Todd, Mark Urassa, Doris Mbata, Griter Maiseli, Rose Manyalla, John Changalucha, Julius Mngara, Ester Mwinuka, Basia Zaba. Trends in the uptake of voluntary counseling and testing for HIV in rural Tanzania in the context of the scale up of antiretroviral therapy. TM&IH Volume 17, Issue 8, pages e15–e25, August 2012 Busza J, Zaba B, Urassa M. The “Seeded” Focus Group: A strategy to recruit HIV+ community members into treatment research. Sex Transm Infect 2009;85 212-215 Lopman B, Cook A, Smith J, Chawira G, Urassa M, Kumogola Y, Isingo R, Ihekweazu C, Ruwende J, Ndege M, Gregson S, Zaba B, Boerma T.Verbal autopsy can consistently measure AIDS mortality: a validation study in Tanzania and Zimbabwe. J Epidemiol Community Health. 2010 Apr;64(4):330-4. Epub 2009 Oct 23. Keogh SC, Urassa M, Kumogola Y, Mngara J, Zaba B. Reproductive behaviour and HIV status of antenatal clients in northern Tanzania: opportunities for family planning and preventing mother-to-child transmission integration. AIDS. 2009 Nov;23 Suppl 1:S27-35 Mwanga JR, Lwambo NJS, Rumisha SF, Vounatsou P, Utzinger J. Dynamics of people’s socio-economic status in the face of schistosomiasis control intervention in Ukerewe district, Tanzania. Acta Tropica 128 (2013) 399406. Fabian M. Mashauri, Safari M. Kinunghi,’ Godfrey M Kaatano, Stephen M. Magesa, Colman Kishamawe, Joseph R Mwanga, Soori E Nnko, Robert C. Malima, Chacha N. Mero, and Leonard E. G. Mboera. Impact of 3. 4. 5. 82. Fabian Mashauri National Institute for Medical Research/Mwanza Intervention Trials Unit IDs (Malaria) 1. 2. indoor residual spraying of lambdacyhalothrin on malaria prevalence and anemia in an epidemic-prone district of Muleba, north-western Tanzania. Am. J. Trop. Med. Hyg. 88 (5), 2013, pp. 841-849 doi:10.4269/ajtmh.12-0412. Mosha FF, Wambura M, Mwanga JR, Mosha JF, Mshana G, and Changalucha J. Readiness of health facilities to deliver safe male circumcision services in Tanzania: a descriptive study. Health Care in Low-resource Settings 2013; 1e9: 34-39. Safari M. Kinunghi’, Fabian Mashauri, Joseph R Mwanga, Soori E Nnko, Godfrey M Kaatano, Robert Malima, Colman Kishamawe, Stephen Magesa and Leonard E G Mboera. Knowledge, attitudes and practices about malaria among communities in an epidemic prone district of Muleba, North-western Tanzania. BMC Public Health 2010; 10: 395. Gerry Mshana, Mwita Wambura, Joseph Mwanga, Jacklin Mosha, Frank Mosha and John Changalucha. ‘Traditional Male Circumcision Practices among the Kurya of Northeastern Tanzania and Implications for National Programme.’ AIDS Care 2011; 23 (9) 1111-1116. Fabian M. Mashauri, Safari M. Kinung’hi, Godfrey M. Kaatano, Stephen M. Magesa, Coleman Kishamawe, Joseph R. Mwanga, Soori E. 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Periodontal conditions, low birth weight and preterm birth among postpartum mothers in two tertiary health facilities in Uganda.BMC Oral Health. 2014 Apr 28;14:42. 2. Wandera M, Astrøm AN, Okullo I, Tumwine JK. Determinants of periodontal health in pregnant women and association with infants' anthropometric status: a prospective cohort study from Eastern Uganda.BMC Pregnancy Childbirth. 2012 Sep 5;12:90. 3. Rwenyonyi CM, Kutesa A, Muwazi L, Okullo I, Kasangaki A, Kekitinwa A. Oral Manifestations in HIV/AIDS-Infected Children.Eur J Dent. 2011 Jul;5(3):291-8. 4. Mbalinda SN, Plover CM, Burnham G, Kaye D, Mwanika A, Oria H, Okullo I, Muhwezi W, Groves S. Assessing community perspectives of the community based education and service model at Makerere University, Uganda: a qualitative evaluation.BMC Int Health Hum Rights. 2011 Mar 9;11 Suppl 1:S6. 5. Mwanika A, Okullo I, Kaye DK, Muhwezi W, Atuyambe L, Nabirye RC, Groves S, Mbalinda S, Burnham G, Chang LW, Oria H, Sewankambo N. 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Prediction of width of un-erupted incisors, canines and premolars in a Ugandan population: a cross sectional study.BMC Oral Health. 2012 Jul 23;12:23. 4. Rwenyonyi CM, Kutesa A, Muwazi L, Okullo I, Kasangaki A, Kekitinwa A. Oral Manifestations in HIV/AIDS-Infected Children.Eur J Dent. 2011 Jul;5(3):291-8. 1. Munabi IG, Buwembo W, Kitara DL, Ochieng J, Nabirye RC, Mwaka ES. Musculoskeletal disorders among nursing staff: a comparison of five hospitals in Uganda. Pan Afr Med J. 2014 Jan 31;17:81. 2. Njie-Carr V, Kalengé S, Kelley J, Wilson A, Muliira JK, Nabirye RC, Glass N, Bollinger R, Alamo-Talisuna S, Chang LW. Research capacity-building program for clinicians and staff at a community-based HIV clinic in Uganda: A pre/post evaluation. J Assoc Nurses AIDS Care. 2012 Sep-Oct;23(5):431-41. 3. Nabirye RC, Brown KC, Pryor ER, Maples EH. Occupational stress, job satisfaction and job performance among hospital nurses in Kampala, Uganda. J Nurs Manag. 2011 Sep;19(6):760-8. 4. Mwanika A, Okullo I, Kaye DK, Muhwezi W, Atuyambe L, Nabirye RC, Groves S, Mbalinda S, Burnham G, Chang LW, Oria H, Sewankambo N. Perception and valuations of community-based education and service by alumni at Makerere University College of Health Sciences. BMC Int Health Hum Rights. 2011 Mar 9;11 Suppl 1:S5. 5. Kaye D, Mwanika A, Burnham G, Chang LW, Mbalinda 138. Robert Odoi Adome MakCHS NCDs, HS 1. 2. 3. 4. 5. 139. Joan Nakayaga Kalyango MakCHS IDs-Malaria 1. SN, Okullo I, Nabirye RC, Muhwezi W, Oria H, Kijjambu S, Atuyambe L, Aryeija W. The organization and implementation of community-based education programs for health worker training institutions in Uganda. BMC Int Health Hum Rights. 2011 Mar 9;11 Suppl 1:S4. MacDonald NE, Bortolussi R, Kabakyenga J, Pemba S, Estambale B, Kollmann KH, Odoi Adome R, Appleton M.MicroResearch: Finding sustainable local health solutions in East Africa through small local research studies. J Epidem iol Glob Health. 2014 Sep;4(3):185-93 Okello E, Beaton A, Mondo CK, Kruszka P, Kiwanuka N, Odoi-Adome R, Freers J. Rheumatic heart disease in Uganda: the association between MHC class II HLA DR alleles and disease: a case control study.BMC Cardiovasc Disord. 2014 Feb 28;14:28. Okello E, Wanzhu Z, Musoke C, Twalib A, Kakande B, Lwabi P, Wilson NB, Mondo CK, Odoi-Adome R, Freers J. Cardiovascular complications in newly diagnosed rheumatic heart disease patients at Mulago Hospital, Uganda.Cardiovasc J Afr. 2013 Apr;24(3):80-5. Okello E, Kakande B, Sebatta E, Kayima J, Kuteesa M, Mutatina B, Nyakoojo W, Lwabi P, Mondo CK, OdoiAdome R, Juergen F. Socioeconomic and environmental risk factors among rheumatic heart disease patients in Uganda.PLoS One. 2012;7(8):e43917. Wiens MO, MacLeod S, Musiime V, Ssenyonga M, Kizza R, Bakeera-Kitaka S, Odoi-Adome R, Ssali F. Paediatr Drugs. 2012 Oct 1;14(5):331-5. Adherence to antiretroviral therapy in HIV-positive adolescents in Uganda assessed by multiple methods: a prospective cohort study. Kalyango JN, Rutebemberwa E, Karamagi C, Mworozi E, Ssali S, Alfven T, Peterson S. High adherence to antimalarials and antibiotics under integrated community 140. Annette Nakimuli MakCHS M/RH case management of illness in children less than five years in eastern Uganda. PLoS One. 2013;8(3):e60481. 2. Kalyango JN, Lindstrand A, Rutebemberwa E, Ssali S, Kadobera D, Karamagi C, Peterson S, Alfven T. Increased use of community medicine distributors and rational use of drugs in children less than five years of age in Uganda caused by integrated community case management of fever. Am J Trop Med Hyg. 2012 Nov;87(5 Suppl):36-45 3. Kalyango JN, Alfven T, Peterson S, Mugenyi K, Karamagi C, Rutebemberwa E Integrated community case management of malaria and pneumonia increases prompt and appropriate treatment for pneumonia symptoms in children under five years in Eastern Uganda. Malar J. 2013 Sep 22;12:340. doi: 10.1186/1475-2875-12-340. 4. Ochola E, Ocama P, Orach CG, Nankinga ZK, Kalyango JN, McFarland W, Karamagi C. High burden of hepatitis B infection in Northern Uganda: results of a population-based survey. BMC Public Health. 2013 Aug 7;13:727. doi: 10.1186/1471-2458-13-727. 5. Buregyeya E, Nuwaha F, Verver S, Criel B, Colebunders R, Wanyenze R, Kalyango JN, Katamba A, Mitchell EM. Implementation of tuberculosis infection control in health facilities in Mukono and Wakiso districts, Uganda. BMC Infect Dis. 2013 Aug 1;13:360. doi: 10.1186/1471-233413-360. 1. Kaye DK, Kakaire O, Nakimuli A, Mbalinda SN, Osinde MO, Kakande N. 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Payne BA, Hutcheon JA, Ansermino JM, Hall DR, Bhutta ZA, Bhutta SZ, Biryabarema C, Grobman WA, Groen H, Haniff F, Li J, Magee LA, Merialdi M, Nakimuli A, Qu Z, Sikandar R, Sass N, Sawchuck D, Steyn DW, Widmer M, Zhou J, von Dadelszen P; miniPIERS Study Working Group. A risk prediction model for the assessment and triage of women with hypertensive disorders of pregnancy in low-resourced settings: the miniPIERS (Pre-eclampsia Integrated Estimate of RiSk) multi-country prospective cohort study.PLoS Med. 2014 Jan;11(1):e1001589. Nakimuli A, Elliott AM, Kaleebu P, Moffett A, Mirembe F. Hypertension persisting after pre-eclampsia: a prospective cohort study at Mulago Hospital, Uganda.PLoS One. 2013 Dec 31;8(12):e85273. Beaton A, Okello E, Aliku T, Lubega S, Lwabi P, Mondo C, McCarter R, Sable C. Latent rheumatic heart disease: outcomes 2 years after echocardiographic detection.Pediatr Cardiol. 2014 Oct;35(7):1259-67. 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A descriptive analysis of the institutional frameworks for disaster management in Uganda: structures, functions and gaps. East Afr J Public Health. 2013 Jun;10(2):46975. 143. Fred Kironde 144. Jackson Oryem MakCHS NCDs-Malaria MakCHS NTDs-Oncology 5. Orach CG, Mayega RW, Woboya V, Bazeyo William. Performance of district disaster management teams after undergoing an operational level planners' training in Uganda. East Afr J Public Health. 2013 Jun;10(2):459-68. 1. Bwayo D, Kaddumukasa M, Ddungu H, Kironde F. Prevalence of glucose-6-phosphate dehydrogenase deficiency and its association with Plasmodium falciparum infection among children in Iganga distric in Uganda. BMC Res Notes. 2014 Jun 18;7:372. doi: 10.1186/1756-05007-372. 2. Kiwuwa MS, Byarugaba J, Wahlgren M, Kironde F. 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Orem J, Sandin S, Weibull CE, Odida M, Wabinga H, Mbidde E, Wabwire-Mangen F, Meijer CJ, Middeldorp JM, Weiderpass E.Agreement between diagnoses of childhood lymphoma assigned in Uganda and by an international reference laboratory. Clin Epidemiol. 2012;4:339-47. doi: 10.2147/CLEP.S35671. Epub 2012 Dec 14. 5. Okuku F, Omoding A, Walusansa V, Origa M, Mutungi G, Orem J. Infection-related cancers in sub-saharan Africa: a paradigm for cancer prevention and control. Oncology. 2013;84(2):75-80. doi: 10.1159/000343151. Epub 2012 Oct 31 1. Kiwuwa MS, Ribacke U, Moll K, Byarugaba J, Lundblom K, Färnert A, Fred K, Wahlgren M. Genetic diversity of Plasmodium falciparum infections in mild and severe malaria of children from Kampala, Uganda. Parasitol Res. 2013 Apr;112(4):1691-700. doi: 10.1007/s00436-013-3325-3. 2. Angeletti D, Kiwuwa MS, Byarugaba J, Kironde F, Wahlgren M. Elevated levels of high-mobility group box-1 146. 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Healthcare Design: Simulation in Healthcare, Systems modelling, Complex systems, Systems approach, Systems thinking, Service Design 1. 2. 3. 4. 5. 191. Prof Andrew Lever Professor of Infectious Infectious Diseases/HIV. Retrovirus and rotavirus 1. the Disease Vector Aedes aegypti onto a Genetic Linkage Map Allows Mapping of Genes Affecting Disease Transmission. PLoS Neglected Tropical Diseases. 8: e2652 [PDF] Gracey, F and Komashie, A and Malley, D (2012) Models, Simulations and Metacognition: Reflections on Interactions between Systems Engineering and Neuropsychology in Brain Injury Rehabilitation. BRAIN INJURY, 26. pp. 619-620. ISSN 0269-9052 KOMASHIE, A., Jun, T., Dodds, S., Rayner, H., Thane, S., Mitchell-Baker, A.and Clarkson, P. J. (2011) 'SICK SYSTEMS: Towards a generic conceptual representation of healthcare systems' Proceedings of the 18th International Conference on Engineering Design (ICED11), Vol. 4 (pp. 430440). Mousavi, A., KOMASHIE, A., and Tavakoli, S. (2011) 'SIMULATION-BASED REAL-TIME PERFORMANCE MONITORING (SIMMON): A PLATFORM FOR MANUFACTURING AND HEALTHCARE SYSTEMS', in Proc. 43rd Winter Simulation Conference, 2011, Arizona, USA.(S. Jain, R. R. Creasey, J. Himmelspach, K. P. White, & M. Fu, Eds.). Komashie, A and Mousavi, A and Gore, J (2008) Using Discrete Event Simulation (DES) to manage theatre operations in healthcare: An audit-based case study.Proceedings - UKSim 10th International Conference on Computer Modelling and Simulation, EUROSIM/UKSim2008. pp. 360-365. Komashie, A and Mousavi, A and Gore, J (2007) Quality management in healthcare and industry: A comparative review and emerging themes. Journal of Management History, 13. pp. 359-370. Current perspectives on RNA secondary structure probing. Kenyon J, Prestwood L, Lever A. Biochem Soc Diseases, Dept of Medicine 192. Prof Nick Mascie-Taylor molecular biology: HIV, Rotavirus, Molecular biology, Structural biology, RNA packaging, RNA structure, Pathogen biology and evolution, Virology NCD. Nutrition, Disease, Professor of Human Population Growth and Poverty in Biology and Health; Developing Countries Deputy Head, Dept of Biological Anthropology Trans. 2014 Aug 1 2. Targeting RNA-protein interactions within the human immunodeficiency virus type 1 lifecycle.Bell NM, L'Hernault A, Murat P, Richards JE, Lever AM, Balasubramanian S. Biochemistry. 2013 Dec 23 3. World AIDS Day: together we will stop HIV transmission and conquer AIDS. Wainberg MA, Lever A. Retrovirology. 2013 Nov 15 4. Further characterisation of rotavirus cores: Ss(+)RNAs can be packaged in vitro but packaging lacks sequence specificity. Desselberger U, Richards J, Tchertanov L, Lepault J, Lever A, Burrone O, Cohen J. Virus Res. 2013 Dec 26 5. Experimental pathways towards developing a rotavirus reverse genetics system: synthetic full length rotavirus ssRNAs are neither infectious nor translated in permissive cells. Richards JE, Desselberger U, Lever AM.PLoS One. 2013 Sep 3 1. Krzyżanowska M & Mascie-Taylor CGN (2014) Educational and social class assortative mating in fertile British couples. Annals of Human Biology 2. Basu Mallick C, Iliescu FM, Möls M, Hill S, Tamang R, Chaubey G, Goto R, Ho SY, Gallego Romero I, Crivellaro F, Hudjashov G, Rai N, Metspalu M, Mascie-Taylor CGN, Pitchappan R, Singh L, Mirazon-Lahr M, Thangaraj K, Villems R & Kivisild (2013) The light skin allele of SLC24A5 in South Asians and Europeans shares identity by descent. PLoS Genetics. 9(11):e1003912. 3. Rohner F, Northrop-Clewes C, Tschannen AB, Bosso PE, Kouassi-Gohou V, Erhardt JG, Bui M, Zimmermann MB &Mascie-Taylor CGN (2013) Prevalence and public health relevance of micronutrient deficiencies and undernutrition in pre-school children and women of reproductive age in Côte d'Ivoire, West Africa. Public 193. Dr TJ McKinley Research Associate in Statistics, Cambridge Infectious Diseases Consortium, Dept of Veterinary Medicine Infectious Disease/Cross-cutting. Statistical Methodology For Studying Infectious Diseases: Statistical modelling, Bayesian methods, MCMC, Influenza, Salmonellosis 194. Dr Richard Meiser-Stedman MRC Clinician Scientist Fellow, MRC Cognition & Brain Sciences Unit Mental Health. PostTraumatic Stress Disorder : anxiety, trauma, children, adolescents, genetic and psychophysiological factors Health Nutrition. 4:1-13. 4. Krzyżanowska M & Mascie-Taylor CGN (2013) Biosocial correlates of intergenerational social mobility in a British cohort. Journal of Biosocial Science, 45(4):481-96. 5. Mascie-Taylor CGN (2012) Is Bangladesh going through an epidemiological and nutritional transition?, Collegium antropologicum, 36(4):1155-9. 1. The demography of free‐roaming dog populations and applications to disease and population controlMK M orters, TJ McKinley, O Restif, AJK Conlan, S Cleaveland, Journal of Applied Ecology 2014 2. Simulation-based Bayesian inference for epidemic models TJ McKinley, JV Ross, R Deardon, AR Cook Computational Statistics & Data Analysis 2014 3. Achieving population-level immunity in rabies to freeroaming dogs in Africa and Asia MK Morters, TJ McKinley, DL Horton, S Cleaveland, JP Schoeman, PLOS 2014 4. Bayesian Model Choice in Cumulative Link Ordinal Regression Models TJ McKinley, M Morters, JLN Wood 2014 5. Nested sampling for bayesian model comparison in the context of salmonella disease dynamics R Dybowski, TJ McKinley, P Mastroeni, O Restif PloS one 8 (12), e82317 2013 1. Amone-P’Olak, K., Stochl, J., Ovuga, E., Abbott, R., Meiser-Stedman, R., Croudace, T.J., & Jones, P.B. (2014). Post-war Environment and Long-Term Mental Health Problems in Former Child Soldiers in Northern Uganda: The WAYS Study. Journal of Epidemiology & Community Health. 2. Amone-P’Olak, K., Jones, P.B., Meiser-Stedman, R., Abbott, R., Ayella-ataro, P., & Ovuga, E. (2014) War experiences, General Functioning, and Barriers to Care 3. 4. 5. 195. Dr Gos Micklem Director, Cambridge Computational Biology Institute, Dept of Applied Mathematics and Theoretical Physics; Dept of Genetics Cross-cutting. Bioinformatics; Genomics; Synthetic Biology: 1. 2. 3. 4. among Former Child Soldiers in Northern Uganda: The WAYS Study. Journal of Public Health. Meiser-Stedman, R., Shepperd, A., Glucksman, E., Dalgleish, T., Yule, W., & Smith, P. (2014). Thought control strategies and rumination in youth with acute stress disorder and posttraumatic stress disorder following single-event trauma. Journal of Child and Adolescent Psychopharmacology, 24, 47-51. Open Access pdf Amone-P’Olak, K., Jones, P.B., Abbott, R., MeiserStedman, R., Ovuga, E., & Croudace, T.J. (2013). Cohort profile: mental health following extreme trauma in a northern Ugandan cohort of War-Affected Youth Study (The WAYS Study). SpringerPlus, 2, 1-11. pdf Nixon, R.D.V., Meiser-Stedman, R., Dalgleish, T., Yule, W., Clark, D.M., Perrin, S., & Smith, P. (2013). The Child PTSD Symptom Scale: An update and replication of its psychometric properties.Psychological Assessment, 25, 1025-1031. esyN: Network Building, Sharing and Publishing. Bean DM, Heimbach J, Ficorella L, Micklem G, Oliver SG, Favrin G. PLoS One. 2014 Sep 2;9(9):e106035. doi: 10.1371/journal.pone.0106035. eCollection 2014. InterMine: extensive web services for modern biology. Kalderimis A, Lyne R, Butano D, Contrino S, Lyne M, Heimbach J, Hu F, Smith R, Stěpán R, Sullivan J, Micklem G. Nucleic Acids Res. 2014 Jul;42(Web Server issue):W468-72. doi: 10.1093/nar/gku301. Epub 2014 Apr 21 Identification of microRNAs in the coral Stylophora pistillata. Liew YJ, Aranda M, Carr A, Baumgarten S, Zoccola D, Tambutté S, Allemand D, Micklem G, Voolstra CR. PLoS One. 2014 Mar 21;9(3):e91101. doi: 10.1371/journal.pone.0091101. eCollection 2014 BioJS DAGViewer: A reusable JavaScript component 5. 196. Prof Ashley Moffett Professor of Reproductive Immunology, Dept of Pathology Maternal health. Immune Systems & Regulation Of Placentation: Preeclampsia, Still-birth, Recurrent miscarriage and Poor fetal growth 1. 2. 3. 4. 5. 197. Dr Sergey Nejentsev Royal Society Research Fellow, Dept of Medicine Infectious Disease/TB. Genetics of Infection (TB): Tuberculosis, 1. for displaying directed graphs. Kalderimis A, Stepan R, Sullivan J, Lyne R, Lyne M, Micklem G. F1000Res. 2014 Feb 13;3:51. doi: 10.12688/f1000research.3-51.v1. eCollection 2014 Integrating microRNA and mRNA expression profiling in Symbiodinium microadriaticum, a dinoflagellate symbiont of reef-building corals. Baumgarten S, Bayer T, Aranda M, Liew YJ, Carr A, Micklem G, Voolstra CR. BMC Genomics. 2013 Oct 12;14:704.doi: 10.1186/1471-216414-704. Hiby SE, Apps R, Chazara O, Farrell LE, Magnus P, Trogstad L, Gjessing HK, Carrington M, Moffett A. (2014) Maternal KIR in combination with paternal HLA-C2 regulate human birth weight. J Immunol. 192(11):5069-73. Moffett A, Colucci F. (2014) Uterine NK cells: active regulators at the maternal-fetal interface. J Clin Invest. 124(5):1872-9. Kieckbusch J, Gaynor LM, Moffett A, Colucci F. (2014) MHC-dependent inhibition of uterine NK cells impedes fetal growth and decidual vascular remodelling. Nat Commun 5:3359. Nakimuli A, Chazara O, Byamugisha J, Elliott AM, Kaleebu P, Mirembe F,Moffett A. (2014) Pre-eclampsia, pregnancy and parturition in women of African ancestry. American Journal of Obstetrics and Gynecology 210(6):510-520. Nakimuli A, Elliott AM, Kaleebu P, Moffett A, Mirembe F. (2013) Hypertension persisting after pre-eclampsia: a prospective cohort study at Mulago Hospital, Uganda. PLoS One Dec 31 Angulo I, Vadas O, Garçon F, Banham-Hall E, Plagnol V, Leahy TR, Baxendale H, Coulter T, Curtis J, Wu C, BlakePalmer K, Perisic O, Smyth D, Maes M, Fiddler C, Juss J, Genetic susceptibility, Enterovirus, Host pathogen interaction, Immunity and host defences, Immunogenetics, Innate immunity 2. 3. 4. 198. Dr Michelle Oyen Lecturer in Mechanics of Biological Materials, Dept of Engineering Maternal health. Engineering Factors In Premature Birth: Biomedical engineering, mechanics of connective 1. Cilliers D, Markelj G, Chandra A, Farmer G, Kielkowska A, Clark J, Kracker S, Debré M, Picard C, Pellier I, Jabado N, Morris JA, Barcenas-Morales G, Fischer A, Stephens L, Hawkins P, Barrett JC, Abinun M, Clatworthy M, Durandy A, Doffinger R, Chilvers E, Cant AJ, Kumararatne D, Okkenhaug K, Williams RL, Condliffe A*, Nejentsev S*. Phosphoinositide 3-Kinase δ Gene Mutation Predisposes to Respiratory Infection and Airway Damage. Science. 2013 Oct 17. *shared senior authors Burns SO, Zenner, HL, Plagnol, V, Curtis, J, Mok, K, Eisenhut, M, Kumararatne, D, Doffinger, R, Thrasher, AJ, _Nejentsev, S: LRBA gene deletion in a patient presenting with autoimmunity without hypogammaglobulinemia. J Allergy Clin Immunol, 2012; 130:1428-32. Plagnol V, Curtis J, Epstein M, Mok K, Stebbings E, Grigoriadou S, Wood NW, Hambleton S, Burns SO, Thrasher A, Kumararatne D, Doffinger R, Nejentsev S: A robust model for read count data in exome sequencing experiments and implications for copy number variant calling. Bioinformatics 28:2747-54, 2012 Thye T, Owusu-Dabo E, Vannberg FO, van Crevel R, Curtis J, Sahiratmadja E, Balabanova Y, Ehmen C, Muntau B, Ruge G, Sievertsen J, Gyapong J, Nikolayevskyy V, Hill PC, Sirugo G, Drobniewsk F, van de Vosse E, Newport M, Alisjahbana B, Nejentsev S, Ottenhoff THM, Hill AVS, Horstmann RD, Meyer CG: Common variants at 11p13 are associated with susceptibility to tuberculosis. Nat Genet 44:257-9, 2012 Yao, W and Yoshida, K and Fernandez, M and Vink, J and Wapner, RJ and Ananth, CV and Oyen, ML and Myers, KM (2014) Measuring the compressive viscoelastic mechanical properties of human cervical tissue using indentation. J Mech Behav Biomed Mater, tissues, injury, premature birth, arthritis, biomimetics 34. pp. 18-26. 2. Tonsomboon, K and Koh, CT and Oyen, ML (2014) Time- 3. 4. 5. 199. Prof Julian Parkhill Head of Pathogen Genomics, Wellcome Trust Sanger Institute Infectious Diseases/cross-cutting. Genomics Of Bacterial Pathogens: Genome, sequencing, Bioinformatics, Genetics, Molecular Biology, HostPathogen Interaction, Pathogen Evolution, Infection, Epidemiology, Pathogenesis, Bioinformatics, Bacteriology, Genomics, Typhoid Fever, 1. 2. 3. dependent fracture toughness of cornea. J Mech Behav Biomed Mater, 34. pp. 116-123. Abernathy, MR and Hough, J and Martin, IW and Rowan, S and Oyen, M and Linn, C and Faller, JE (2014) Investigation of the Young's modulus and thermal expansion of amorphous titania-doped tantala films. Appl Opt, 53. pp. 3196-3202. ISSN 1559-128X Liu, K-K and Oyen, ML (2014) Nanobiomechanics of living materials Introduction. INTERFACE FOCUS, 4. ISSN 2042-8898 Caliari, SR and Mozdzen, LC and Armitage, O and Oyen, ML and Harley, BA (2014)Award Winner in the Young Investigator Category, 2014 Society for Biomaterials Annual Meeting and Exposition, Denver, Colorado, April 16-19, 2014: Periodically perforated core-shell collagen biomaterials balance cell infiltration, bioactivity, and mechanical properties. J Biomed Mater Res A, 102. pp. 917-927 Out-of-Africa migration and Neolithic coexpansion of Mycobacterium tuberculosis with modern humans. Comas I, Coscolla M, Luo T, Borrell S, Holt KE, KatoMaeda M, Parkhill J, Malla B, Berg S, Thwaites G, Yeboah-Manu D,Bothamley G, Mei J, Wei L, Bentley S, Harris SR, Niemann S, Diel R, Aseffa A, Gao Q, Young D and Gagneux S Nature genetics 2013;45;10;1176-82 PUBMED:23995134; PMC: 3800747; DOI: 10.1038/ng.2744 What has high-throughput sequencing ever done for us? Parkhill J Nature reviews. Microbiology 2013;11;10;664-5 PUBMED: 23979431; DOI: 10.1038/nrmicro3112 Distinguishable epidemics of multidrug-resistant Staphylococcus aureus, Shigellosis, Burkholderia pseudomallei, Tuberculosis, Diphtheria, Salmonella, Campylobacter Pertussis 200. Dr Emma Pitchforth Research Leader, RAND Europe; Visiting Senior Research Fellow, IPH, University of Cambridge; Visiting Senior Fellow, London School of Economics and Political Science Heath services research. Health Services Research: Mixed methods research, Qualitative research, Hospital ethnography, Maternal- neonatal and child health, Quality of care, Global health, Globalization and health, Salmonella Typhimurium DT104 in different hosts. Mather AE, Reid SW, Maskell DJ, Parkhill J, Fookes MC, Harris SR, Brown DJ, Coia JE, Mulvey MR, Gilmour MW,Petrovska L, de Pinna E, Kuroda M, Akiba M, Izumiya H, Connor TR, Suchard MA, Lemey P, Mellor DJ, Haydon DT andThomson NR Science (New York, N.Y.) 2013;341;6153;1514-7 PUBMED: 24030491; PMC: 4012302; DOI: 10.1126/science.1240578 4. Rapid bacterial whole-genome sequencing to enhance diagnostic and public health microbiology. Reuter S, Ellington MJ, Cartwright EJ, Köser CU, Török ME, Gouliouris T, Harris SR, Brown NM, Holden MT, Quail M,Parkhill J, Smith GP, Bentley SD and Peacock SJ JAMA internal medicine 2013;173;15;1397-404PUBMED: 23857503; PMC: 4001082; DOI: 10.1001/jamainternmed.2013.7734 5. Whole-genome sequencing for rapid susceptibility testing of M. tuberculosis.Köser CU, Bryant JM, Becq J, Török ME, Ellington MJ, Marti-Renom MA, Carmichael AJ, Parkhill J, Smith GP andPeacock SJ The New England journal of medicine 2013;369;3;290-2 PUBMED: 23863072; PMC: 3836233; DOI: 10.1056/NEJMc1215305 1. Multicentre cluster randomised controlled trial evaluating implementation of a fire prevention Injury Prevention Briefing in children’s centres: study protocol Deave, Toity, Towner, Elizabeth, McColl, Elaine, Reading, Richard, Sutton, Alex, Coupland, Carol, Cooper, Nicola, Stewart, Jane, Hayes, Mike, Pitchforth, Emma, Watson, Michael and Kendrick, Denise (2014) Multicentre cluster randomised controlled trial evaluating implementation of a fire prevention Injury Prevention Briefing in children’s centres: study protocol. BMC Public Health, 14 (1). p. 69. Emergency care 2. 3. 4. 5. 201. Dr Julian Rayner Group Leader, Malaria Programme, Wellcome Trust Sanger Institute Malaria. Host-Parasite Interactions At The Molecular Level In Malaria: Malaria, Plasmodium falciparum, Host-parasite interactions, Parasite motility, Red blood cell invasion, Genetic diversity 1. 2. 3. ISSN 1471-2458 Recent RAND publications Ellen Nolte, Emma Pitchforth, Celine Miani, Sheena Mc Hugh. The changing hospital landscape: An exploration of international experiences (Aug 5, 2014) Report Daniel Schweppenstedde, Saba Hinrichs, Uzor Ogbu, Eric C. Schneider, Dionne S. Kringos, Niek S. Klazinga, Judith Healy, Lauri Vuorenkoski, Reinhard Busse, Benoit Guerin, Emma Pitchforth, Ellen Nolte. Regulating quality and safety of health and social care: International experiences (Feb 7, 2014) Report Mark W. Friedberg, Kristin R. Van Busum, Peggy G. Chen, Frances Aunon, Chau Pham, John Caloyeras, Soeren Mattke, Emma Pitchforth, Denise D. Quigley, Robert H. Brook, F. Jay Crosson, Michael Tutty. Factors Affecting Physician Professional Satisfaction (Oct 11, 2013) Research Brief Mark W. Friedberg, Peggy G. Chen, Kristin R. Van Busum, Frances Aunon, Chau Pham, John Caloyeras, Soeren Mattke, Emma Pitchforth, Denise D. Quigley, Robert H. Brook, F. Jay Crosson, Michael Tutty. Factors Affecting Physician Professional Satisfaction and Their Implications for Patient Care, Health Systems, and Health Policy (Oct 8, 2013) Report Quantitation of malaria parasite-erythrocyte cell-cell interactions using optical tweezers. Crick AJ, Theron M, Tiffert T, Lew VL, Cicuta P, Rayner JC. Biophys J. 2014 Aug 19 New antigens for a multicomponent blood-stage malaria vaccine. Osier FH, Mackinnon MJ, Crosnier C, Fegan G, Kamuyu G, Wanaguru M, Ogada E, McDade B, Rayner JC, Wright GJ, Marsh K. Sci Transl Med. 2014 Jul 30 Plasmodium falciparum erythrocyte invasion: combining 4. 5. 202. Dr Mark Reacher Consultant Epidemiologist at the Health Protection Agency and affiliated Lecturer, University of Cambridge Dept of Public Health & Primary Care Malaria/ infectious diseases, Cross-cutting. Infection Malaria, Infectious diseases, cross-cutting. Epidemiology: Infection Surveillance, Epidemiology, Health Protection, Public Health, Enteric viral infections, Cryptosporidiosis, Antibiotic resistance, Immunisation, Malaria, Epidemiology training 1. 2. 3. 4. 5. function with immune evasion. Wright GJ, Rayner JC. PLoS Pathog. 2014 Mar 20 Towards a comprehensive Plasmodium falciparum merozoite cell surface and secreted recombinant protein library. Zenonos ZA, Rayner JC, Wright GJ. Malar J. 2014 Mar 12 A member of the Plasmodium falciparum PHIST family binds to the erythrocyte cytoskeleton component band 4.1. Parish LA, Mai DW, Jones ML, Kitson EL, Rayner JC. Malar J. 2013 May 1 Outbreak of mumps in a school setting, United Kingdom, 2013. Aasheim ET, Inns T, Trindall A, Emmett L, Brown KE, Williams CJ, Reacher M. Hum Vaccin Immunother. 2014 Jun 19 Incidence and risk factors for drug intolerance and association with incomplete treatment for tuberculosis: analysis of national case registers for England, Wales and Northern Ireland, 2001-2010. Smith C, Abubakar I, Thomas HL, Anderson L, Lipman M, Reacher M. Thorax. 2014 Oct Evaluation of community-based trichiasis surgery in Northwest Ethiopia. Pearson K, Habte D, Zerihun M, King JD, Gebre T, Emerson PM, Reacher MH, Ngondi JM. Ethiop J Health Sci. 2013 Jul Programme to vaccinate poultry workers against seasonal influenza: options for delivery in the East of England. Vivancos R, Reacher M, Cosford P; East of England Poultry Workers Seasonal Influenza Vaccination Group. Zoonoses Public Health. 2011 Feb Personal protective equipment and risk for avian influenza (H7N3). Morgan O, Kuhne M, Nair P, Verlander NQ, Preece R, McDougal M, Zambon M, Reacher M. Emerg Infect Dis. 2009 Jan 203. Reid Dr Alice Cambridge Group for the History of Population and Social Structure, Dept of Geography IMaternal health etc. Demography: Mortality, Fertility, Population, Census, Midwives, Health visitors, Infant feeding, Social structure 1. Alice Reid, Eilidh Garrett & Simon Szreter (forthcoming 2. 3. 4. 5. 204. Dr Olivier Restif Royal Society Research Fellow, Dept of Veterinary Medicine Infectious Diseases/cross-cutting. Infectious Disease Dynamics & Mathematical Models: mathematical modelling, population dynamics, evolution, bacterial infection 1. 2. 3. 2014), 'Residential mobility and child mortality in early twentieth century Belfast', in New approaches of death in the cities during the health transition, Diego Ramiro, Michel Oris, Lucia Pozzi (eds), Springer. Allen Kabagenyi , Larissa Jennings, Alice Reid, Gorette Nalwadda, James Ntozi, Lynn Atuyambe (2014), 'Barriers to male involvement in contraceptive uptake and reproductive health services: a qualitative study of men and women's perceptions in two rural districts in Uganda', Reproductive Health 11:21, DOI:10.1186/1742-4755-11-21. Alice Reid & Eilidh Garrett (2012), 'Doctors and the causes of neonatal death in nineteenth century Scotland', Annales de Demographie Historique 2012(1):149-179. Alice Reid (2012), 'Mrs Killer and Dr Crook: birth attendants and birth outcomes in early twentieth century Derbyshire', Medical History, 56(4): 511-530. DOI: 10.1017/mdh.2012.30. Link to paper. Eilidh Garrett, Alice Reid & Simon Szreter (2012), 'Fertility and child mortality in a household setting: comparative perspectives from UK censuses, 18611921', Popolazione e Storia, 2010(2) 59-82. The effects of vaccination and immunity on bacterial infection dynamics in vivo. Coward C, Restif O, Dybowski R, Grant AJ, Maskell DJ, Mastroeni P. PLoS Pathog. 2014 Sep 1 Spread and Transmission of Bacterial Pathogens in Experimental Populations of the Nematode Caenorhabditis elegans. Diaz SA, Restif O. Appl Environ Microbiol. 2014 Sep Nested sampling for Bayesian model comparison in the context of Salmonella disease dynamics. Dybowski R, 4. 5. 205. Prof Martin Roland Professor of Health Services Research, Institute of Public Health NCD/Health Systems. Health Services Research & Quality Of Care, Primary Care 1. 2. 3. 4. 5. 206. Prof Derek Smith Professor of Infectious Disease Informatics, Dept of Zoology Malaria & NTDs. Antigenic Variation In Malaria & Dengue Fever: influenza, antigenic, immunisation, 1. McKinley TJ, Mastroeni P, Restif O. PLoS One. 2013 Dec 20 Modelling the dynamics of an experimental host-pathogen microcosm within a hierarchical Bayesian framework. Lunn D, Goudie RJ, Wei C, Kaltz O, Restif O. PLoS One. 2013 Aug 2 Demography of straw-colored fruit bats in Ghana. Hayman DT, McCrea R, Restif O, Suu-Ire R, Fooks AR, Wood JL, Cunningham AA, Rowcliffe JM. J Mammal. 2012 Oct Langenberg, C. et al., 2014. Gene-lifestyle interaction and type 2 diabetes: the EPIC interact case-cohort study. PLoS medicine, 11(5), p.e1001647. (Download) Roland, M. & Nolte, E., 2014. The future shape of primary care. The British Journal of General Practice: The Journal of the Royal College of General Practitioners, 64(619), pp.63–64. (Download) Burt, J. et al., 2014. Assessing communication quality of consultations in primary care: initial reliability of the Global Consultation Rating Scale, based on the CalgaryCambridge Guide to the Medical Interview. BMJ open, 4(3), p.e004339. (Download) Ahmed, F., Burt, J. & Roland, M., 2014. Measuring Patient Experience: Concepts and Methods. The Patient. (Download) Roland, M. & Campbell, S., 2014. Successes and failures of pay for performance in the United Kingdom. The New England Journal of Medicine, 370(20), pp.1944– 1949. (Download) Koel, BF; Burke, DF; Bestebroer, TM; van der Vliet, S; Zondag, GCM; Vervaet, G; Skepner, E; Lewis, NS; Spronken, MIJ; Russell, CA; Eropkin, MY; Hurt, AC; Barr, IG; de Jong, JC; Rimmelzwaan, GF; Osterhaus, ADME; Fouchier, RAM; Smith, DJ. Substitutions near the immunization, pathogen evolution, Epidemiology and mathematical modelling, Virology 2. 3. 4. 5. receptor binding site determine major antigenic change during influenza virus evolution. Science. (In Press, Oct 2013). Colin A. Russell, Judith M. Fonville, André E. X. Brown, David F. Burke, David L. Smith, Sarah L. James, Sander Herfst, Sander van Boheemen, Martin Linster, Eefje J. Schrauwen, Leah Katzelnick, Ana Mosterín, Thijs Kuiken, Eileen Maher, Gabriele Neumann, Albert D. M. E. Osterhaus, Yoshihiro Kawaoka, Ron A. M. Fouchier, and Derek J. Smith. 2012. The Potential for Respiratory Droplet-Transmissible A/H5N1 Influenza Virus to Evolve in a Mammalian Host. Science 336 (6088):1541-1547 Airborne transmission of influenza A/H5N1 virus between ferrets. Herfst S, Schrauwen EJ, Linster M, Chutinimitkul S, de Wit E, Munster VJ, Sorrell EM, Bestebroer TM, Burke DF, Smith DJ, Rimmelzwaan GF, Osterhaus AD, Fouchier RA. Science.22;336(6088):1534-41. Garten RJ, Davis CT, Russell CA, Shu B, Lindstrom S, Balish A, Sessions WM, Xu X, Skepner E, Deyde V, Okomo-Adhiambo M, Gubareva L, Barnes J, Smith CB, Emery SL, Hillman MJ, Rivailler P, Smagala J, de Graaf M, Burke DF, Fouchier RA, Pappas C, Alpuche-Aranda CM, López-Gatell H, Olivera H, López I, Myers CA, Faix D, Blair PJ, Yu C, Keene KM, Dotson PD Jr, Boxrud D, Sambol AR, Abid SH, St George K, Bannerman T, Moore AL, Stringer DJ, Blevins P, Demmler-Harrison GJ, Ginsberg M, Kriner P, Waterman S, Smole S, Guevara HF, Belongia EA, Clark PA, Beatrice ST, Donis R, Katz J, Finelli L, Bridges CB, Shaw M, Jernigan DB, Uyeki TM, Smith DJ, Klimov AI, Cox NJ. 2009. 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The PRIME trial protocol: evaluating the impact of an intervention implemented in public health centres on management of malaria and health outcomes of children using a cluster-randomised design in Tororo, Uganda. Implement Sci 8(1): 114. 4. Mpimbaza A, Filler S, Katureebe A, Kinara S, Nzabandora E, Quick L, Ratcliffe A, Wabwire-Mangen F, Chandramohan D, Staedke SG (2011) Validity of verbal autopsy (VA) procedures for determining malaria deaths in different epidemiological settings in Uganda. PLoS ONE 6(10): e2689 224. Helen Weiss LSHTM epidemiology, randomised controlled trials, HIV, mental health 5. Staedke SG, Mwebaza N, Kamya MR, Clark TD, Dorsey G, Rosenthal PJ, Whitty CJ (2009) Home management of malaria with artemether-lumefantrine compared with standard care in urban Ugandan children: a randomised controlled trial. Lancet 373: 1623-1631. 1. Francis JM, Grosskurth H, Changlucha J, Kapiga SH, Weiss HA. The prevalence of alcohol use among young people in Eastern Africa: Systematic review and metaanalysis. Trop Med Int Health. 2014 Jan 31. doi: 10.1111/tmi.12267 2. Chatterjee S, Naik S, John S, Dabholkar H, Balaji M, Koschosrke M, Varghese M, Rangaswamy T, Weiss HA, Williams P, Patel V, Thornicroft G. Effectiveness of a community-based intervention for people with schizophrenia and their caregivers in India: The COPSI randomised controlled trial. Lancet. 2014 Apr 19;383(9926):1385-94. doi: 10.1016/S01406736(13)62629-X. Epub 2014 Mar 5. 3. Patel V, Weiss HA, Chowdhary N, Naik S, Pednekar S, Chatterjee S, De Silva M, Bhat B, Araya R, King M, Simon G, Verdeli H, Kirkwood BR. The effectiveness of a lay health worker led intervention for depressive and anxiety disorders in primary care: the Manas cluster randomized controlled trial in Goa, India. Lancet Dec 18;376(9758):2086-95. Epub 2010 Dec 13. 4. Vandepitte J, Bukenya J, Weiss HA, Nakubulwa S, Francis SC, Hughes P, Hayes RJ, Grosskurth H. HIV and Other Sexually Transmitted Infections in a Cohort of Women Involved in High-Risk Sexual Behavior in Kampala, Uganda. Sexually Transmitted Diseases. 38(4):316-323, April 2011. 5. Vandepitte J, Weiss HA, Bukenya J, Nakubulwa S, Mayanja Y, Matovu G, Kyakuwa N, Hughes P, Hayes R, Grosskurth H. Alcohol Use, Mycoplasma genitalium, and 225. Suzanne Filteau LSHTM nutrition and infectious diseases 1. 2. 3. 4. 5. 226. Taane Clark LSHTM genomic epidemiology of infectious disease (TB & malaria) 1. Other STIs Associated With HIV Incidence Among Women at High Risk in Kampala, Uganda. J Acquir Immune Defic Syndr. 2013 Jan 1;62(1):119-26. doi: 10.1097/QAI.0b013e3182777167. Salasibew MM, Filteau S, Marchant T. Measurement of breastfeeding initiation: Ethiopian mothers' perception about survey questions assessing early initiation of breastfeeding. Int Breastfeeding J 2014; DOI: 10.1186/1746-4358-9-13; http://www.internationalbreastfeedingjournal.com/content/ 9/1/13 Rehman AM, Woodd S, Chisenga M, Siame J, Sampson G, PrayGod G, Koethe JR, Kelly P, Filteau S. Appetite testing in HIV-infected African adults recovering from malnutrition and given antiretroviral therapy (ART). Pub Health Nutr, in press. Sanz-Ramos M, Manno D, Kapambwe M, Ndumba I, Musonda KG, Bates M J, Siame J, Monze M, Filteau S, Gompels UA, and CIGNIS study team. Reduced Poliovirus Vaccine Neutralising-Antibody titres in Infants with Maternal HIV- exposure. Vaccine 2013; 31: 2042-2049. Trilok Kumar G, Sachdev HPS, Chellani H, Rehman AM, Singh V, Arora H, Filteau S. Effect of weekly vitamin D supplements to Indian low birth weight term infants on mortality, morbidity, and growth in the first 6 months of life: a randomised controlled trial. BMJ 2011; 342:d2975. Chilenje Infant Growth Nutrition and Infection (CIGNIS) Study Team (2010) Micronutrient fortification to improve growth and health of maternally HIV-unexposed and exposed Zambian infants: a randomised controlled trial. PLoS One 5(6), e11165, published online 2010 June 17 Coll F, McNerney R, Guerra-Assunção JA, Glynn JR, Perdigão J, Viveiros M, Portugal I, Pain A, Martin N, Clark TG. A robust SNP barcode for typing Mycobacterium 2. 3. 4. 5. 227. Philippe Mayaud LSHTM Clinical epidemiology; clinical trials, HIV, human papillomavirus (HPV) 1. 2. tuberculosis complex strains. Nature Comm. 2014 (in press) Malaria Genomic Epidemiology Network (TG Clark, Senior statistical author). Re-evaluation of genetic associations with severe malaria in 12,000 cases and 17,000 controls. Nature Genetics 2014 (in press) Preston MD, Campino S, Assefa SA, …., Sutherland CJ, Roper C, Clark TG. A barcode of organellar genome polymorphisms identifies the geographic origin of Plasmodium falciparum strains. Nature Commun. 2014 Jun 13;5:4052. doi: 10.1038/ncomms5052. Kafsack BFC, Rovira-Graells N, Clark TG, Crowley VM, Campino SG, Williams AE, Drought LG, Kwiatkowski DP, Baker DA, Cortés A, Llinás M. A transcriptional switch underlies commitment to sexual development in malaria parasites. Nature. 2014 Feb 23. doi: 10.1038/nature12920. Preston MD, Assefa S, Ocholla H, Sutherland CJ, Borrmann S, Nzila A, Michon P, Hien TT, Bousema T, Drakeley CJ, Zongo I, Ouedraogo JB, Djimde AA, Doumbo OK, Nosten F, Fairhurst RM, Conway DJ, Roper C, Clark TG. PlasmoView: A web-based resource to visualise global Plasmodium falciparum genomic variation. J Infect Dis. 2013 Dec 12. Chico M, Mayaud P, Ariti C, Ronsmans C, Mabey D, Chandramohan D. A systematic review and meta-analysis of malaria and sexually transmitted and reproductive tract infections (STI/RTI) in pregnancy in sub-Saharan Africa: Opportunities for antenatal intervention. Journal of the American Medical Association (JAMA) 2012, May 16; 307(19):2079-86. Watson-Jones D, Baisley K, Ponsiano R, Lemme F, Remes P, Ross D, Kapiga S, Mayaud P, de Sanjosé S, Wight D, Changalucha J, Hayes R. Human Papillomavirus 3. 4. 5. 228. Paul Milligan LSHTM Vaccines, malaria, epidemiology and control, medical statistics 1. 2. vaccination in Tanzanian schoolgirls: cluster-randomised trial comparing two vaccine delivery strategies. Journal of Infectious Diseases 2012; ep 1; 206(5):678-86. Sow PS, Watson-Jones D, Kiviat N, Changalucha J, Diallo Mbaye K, Brown J, Bousso K, Kavishe B, Andreasen A, Toure M, Kapiga S, Mayaud P, Hayes R, Lebacq M, Herazeh M, Thomas F, Descamps D. Safety and Immunogenicity of Human Papillomavirus-16/18 AS04Adjuvanted Vaccine: A Randomized Trial in 10-25-YearOld HIV-Seronegative African Girls and Young Women. Journal of Infectious Diseases 2013 Jun; 207(11):175363. Ngou J, Magooa MP, Gilham C, Djigma F, Didelot MN, Kelly H, Yonli A, Sawadogo B, Lewis DA, DelanyMoretlwe S, Mayaud P, Segondy M for the HARP Study Group. Comparison of CareHPV and Hybrid Capture 2 Assays for Detection of High-Risk HPV DNA in Cervical Samples from HIV1-Infected African Women. Journal of Clinical Microbiology 2013 Dec; 51(12):4240-2. Low AJ, Konate I, Nagot N, Weiss HA, Kania D, Vickerman P, Segondy M, Mabey D, Pillay D, Meda N, van de Perre P, Mayaud P. Cervico-vaginal HIV-1 shedding in women taking antiretroviral therapy in Burkina Faso: A longitudinal study. Journal of Acquired Immune Deficiency Syndrome (JAIDS) 2014; 90(2):100-3. Effect of intermittent preventive treatment for malaria during infancy on serological responses to measles and other vaccines used in the Expanded Programme on Immunization: results from five randomised controlled trials. (2012). Crawley J., Sismanidis C., Goodman T., Milligan P. Lancet 380(9846):1001-10 Two Strategies for the Delivery of IPTc in an Area of Seasonal Malaria Transmission in The Gambia: A Randomised Controlled Trial (2011) Bojang K.A., Akor F., 3. 4. 5. 229. Stephen Lawn LSHTM Clinical studies in TB & HIV, diagnostics 1. 2. Conteh L., Webb E., Bittaye O., Conway D.J., Jasseh M., Wiseman V., Milligan P.J., Greenwood B. PLoS Med 2011; 8(2):e1000409 New Malaria-Control Policies and Child Mortality in Senegal: Reaching Millennium Development Goal (2012) Jean-François Trape, Claire Sauvage, Ousmane Ndiaye, Laëtitia Douillot, Adama Marra, Aldiouma Diallo, Badara Cisse, Brian Greenwood, Paul Milligan, Cheikh Sokhna and Jean-François Molez. J Infect Dis. (2012) 205 (4): 672-679. Analysis of partial and complete protection in malaria cohort studies (2013) Matthew E Cairns, Kwaku Poku Asante, Seth Owusu-Agyei, Daniel Chandramohan, Brian M Greenwood, and Paul J Milligan. Malaria Journal 12:355 Haplotype Analyses of Haemoglobin C and Haemoglobin S and the Dynamics of the Evolutionary Response to Malaria in Kassena-Nankana District of Ghana (2012). Anita Ghansah, Kirk A. Rockett, Taane G. Clark, Michael D. Wilson, Kwadwo A. Koram, Abraham R. Oduro, Lucas Amenga-Etego, Thomas Anyorigiya, Abraham Hodgson, Paul Milligan, William O. Rogers, Dominic P. Kwiatkowski. PLoS ONE 7(4): e34565. doi:10.1371/journal.pone.0034565 Lawn SD, Kerkhoff AD, Vogt M, Wood R. Diagnostic accuracy of a low-cost, urine antigen, point-of-care assay for screening for HIV-associated tuberculosis prior to antiretroviral therapy: a descriptive study. Lancet Infect Dis 2012; 12: 201-209. Lawn SD, Brooks SV, Kranzer K, Nicol M, Whitelaw A, Vogt M, Bekker LG, Wood R. Screening for HIVassociated tuberculosis and rifampicin resistance prior to antiretroviral therapy using Xpert MTB/RIF assay: a prospective study. PLoS Med 2011; 8: e1001067. 230. David Moore LSHTM MDRTB transmission and management, diagnostics, TB control 3. Kranzer K, Houben R, Glynn JR, Bekker LG, Wood R, Lawn SD. Yield of HIV-associated tuberculosis during intensified case finding in resource-limited settings: systematic review and meta-analysis. Lancet Infect Dis 2010; 10:93-102. 4. Lawn SD, Kerkhoff AD, Vogt M, Ghebrekristos Y, Whitelaw A, Wood R. Characteristics and early outcomes of patients with Xpert MTB/RIF-negative pulmonary tuberculosis diagnosed during screening prior to antiretroviral therapy. Clin Infect Dis 2012; 54: 1071-1079. 5. Lawn SD, Mwaba P, Bates M, Piatek A, Alexander H, Marais BJ, Cuevas LE, Mchugh TD, Zijenah L, Kapata N, Abubakar I, McNerney R, Hoelscher M, Memish Z, Migliori GB, Hafner R, Kim P, Maeurer M, Schito M, Zumla A. Advances in tuberculosis diagnostics: the Xpert MTB/RIF assay and future prospects for a point-of-care test. Lancet Infect Dis 2013; 13: 349-361. 1. Sheen P, Couvin D, Grandjean L, Zimic M, Dominguez M, Luna G, Gilman RH, Rastogi N, Moore DAJ. Genetic diversity of Mycobacterium tuberculosis in Peru and exploration of phylogenetic associations with drug resistance. PLoS One 2013; 8 (6): e65873 2. Fitzwater SP, Sechler GA, Jave O, Coronel J, Mendoza A, Gilman RH, Friedland JS, Moore DAJ. Second‐line anti‐TB drug concentrations for susceptibility testing in MODS assay. Eur Resp J 2013; 41:1-9 3. Requena-Mendez A, Davies G, Ardrey A, Jave O, LopezRomero SL, Ward SA, Moore DA. Pharmacokinetics of rifampin in Peruvian tuberculosis patients with and without comorbid diabetes or HIV. Antimicrob Agents Chemother 2012;56(5):2357-63. 4. Grandjean L, Crossa A, Gilman RH, Herrera C, Bonilla C, Jave O, Cabrera JL, Martin L, Escombe AR, Moore DA. Tuberculosis in household contacts of MDRTB patients. 231. Anthony Scott LSHTM Epidemiology of invasive bacterial infections, Vaccine evaluations, Pneumonia in childhood Int J Tuberc Lung Dis 2011;15:1164-9 5. Reddy KP, Brady MF, Gilman RH, Coronel J, Navincopa M, Ticona E, Chavez G, Sanchez E, Rojas C, Solari L, Valencia J, Pinedo Y, Benites C, Friedland JS, Moore DA. MODS assay for tuberculosis screening before isoniazid preventive therapy in HIV-infected persons. Clin Infect Dis 2010;50(7):988-96. 1. Hammitt LL, Akech DO, Morpeth SC, Karani A, Kihuha N, Nyongesa S, Bwanaali T, Mumbo E, Kamau T, Sharif SK, Scott JAG. Population effect of 10-valent pneumococcal conjugate vaccine on nasopharyngeal carriage of Streptococcus pneumoniae and non-typeable Haemophilus influenzae in Kilifi, Kenya: findings from cross-sectional carriage studies. Lancet Global Health 2014;2(7):e397-405 2. Etyang AO, Munge K, Bunyasi E, Matata L, Ndila C, Kapesa S, Owiti M, Khandwalla I, Brent AJ, Tsofa B, Kabibu P, Morpeth SC, Bauni E, Otiende M, Ojal J, Ayieko P, Knoll MD, Smeeth L, Williams TN, Griffiths UK, Scott JAG. The Burden of Disease Among Hospitalized Adults in Coastal Kenya: Data from Linked Clinical and Demographic Surveillance Systems. Lancet Global Health 2014;2(4):e216-e224 3. Anderson ST, Kaforou M, Brent AJ, Wright VJ, Banwell CM, Chagaluka G, Crampin, AC, Dockrell HM, French N, Hamilton M, Hibberd ML, Kern F, Langford PR, Ling L, Mlotha R, Ottenhoff THM, Pienaar, S, Pillay V, Scott JAG, Twahir H, Wilkinson RJ, Coin LJ, Heyderman RS, Levin M, Eley B, the ILULU consortium and KIDS TB Study Group. Diagnosis of childhood TB in High TB/HIV burden African countries by host RNA expression. N Engl J Med 2014; 370(18):1712-23 4. Feikin DR, Scott JAG, Gessner BD. Using vaccines as probes to define disease burden. Lancet 2014;383:1762- 232. Shabbar Jaffar LSHTM Epidemiology and control of HIV and NCDs, Clinical trials 70 5. Nair H, Simoes EA, Rudan I, Gessner BD, AzzizBaumgartner E, Zhang JS, Feikin DR, Mackenzie GA, Moisi JC, Roca A, Baggett HC, Zaman SM, Singleton RJ, Lucero MG, Chandran A, Gentile A, Cohen C, Krishnan A, Bhutta ZA, Arguedas A, Clara AW, Andrade AL, Ope M, Ruvinsky RO, Hortal M, McCracken JP, Madhi SA, Bruce N, Qazi SA, Morris SS, El Arifeen S, Weber MW, Scott JA, Brooks WA, Breiman RF, and Campbell H. Global and regional burden of hospital admissions for severe acute lower respiratory infections in young children in 2010: a systematic analysis. Lancet 2013:381;1380-90 1. Lazarus J, Jaffar, S. Health service delivery models for the provision of antiretroviral therapy in sub-Saharan Africa: a systematic review. In press, Trop Med Int Health 2014 Jul 28. doi: 10.1111/tmi.12366. 2. Joseph N, Tihana Bicanic, Angela Loyse, Daniel Namarika, Arthur Jackson, Jesse C Nussbaum, Nicky Longley, Conrad Muzoora, Jacob Phulusa, Kabanda Taseera, Creto Kanyembe, Douglas Wilson, Mina C Hosseinipour, Anne-Marie E Brouwer, Direk Limmathurotsakul, Nicholas White, Charles van der Horst, Robin Wood, Graeme Meintjes, John Bradley, Shabbar Jaffar and Thomas Harrison. Determinants of Mortality in a Combined Cohort of 501 Patients with HIV-associated Cryptococcal Meningitis: Implications for Improving Outcomes. Clin Infect Dis 2014; 58: 736-745 3. Woodd SL, Grosskurth H, Levin J, Amuron B, Namara G, Birunghi J, Coutinho A, Jaffar S. Home-based versus clinic-based care for patients starting antiretroviral therapy with low CD4 counts in Uganda: findings from a clusterrandomised trial. AIDS 2014, 28: 569-76. 4. MbonyeM, Seeley J, Ssembajja F, Birungi J, Jaffar S. Adherence to antiretroviral therapy in Jinja, Uganda: a six- 233. Laura Rodrigues LSHTM Epidemiology, immunoepidemiology, statistics, TB, NCDs year follow-up study. PLOS ONE 2013; 8(10): e78243 5. 5. Atun R, Jaffar S, Nishtar S, Knaul FM, Barreto ML, Nyirenda M, Banatvala N, Piot P. Improving responsiveness of health systems to non-communicable diseases. Lancet. 2013; 381: 690-7. 1. Araújo, GS; Pereira, SM; Santos, DN; Marinho, JM; Rodrigues, LC; Barreto, ML; (2014) Common mental disorders associated with tuberculosis: a matched casecontrol study. PLoS One, 9 (6). e99551. ISSN 1932-6203 DOI: 10.1371/journal.pone.0099551 2. Barreto, ML; Pilger, D; Pereira, SM; Genser, B; Cruz, AA; Cunha, SS; Sant'Anna, C; Hijjar, MA; Ichihara, MY; Rodrigues, LC; (2014) Causes of variation in BCG vaccine efficacy: Examining evidence from the BCG REVAC cluster randomized trial to explore the masking and the blocking hypotheses. Vaccine. ISSN 0264-410X DOI: 10.1016/j.vaccine.2014.05.042 3. Cartaxo, CG; Rodrigues, LC; Braga, CP; Ximenes, RA; (2014) Measuring the accuracy of a point system to diagnose tuberculosis in children with a negative smear or with no smear or culture. Journal of epidemiology and global health, 4 (1). pp. 29-34. ISSN 2210-6006 DOI: 10.1016/j.jegh.2013.10.002 4. Endara, PF; Cooper, PJ; Plattsmills, TAE; Workman, LJ; Vaca, M; Chico, M; Barreto, ML; Rodrigues, L; (2014) Urban Residence Modifies The Association Between Atopy and Wheeze. The Journal of allergy and clinical immunology, 133 (2). AB14-AB14. ISSN 0091-6749 5. Ichihara, MY; Rodrigues, LC; Teles Santos, CA; Teixeira, MD; De Jesus, SR; Alvim De Matos, SM; Gagliardi Leite, JP; Barreto, ML; (2014) Effectiveness of rotavirus vaccine against hospitalized rotavirus diarrhea: A case-control study. Vaccine. ISSN 0264-410X DOI: 10.1016/j.vaccine.2014.01.007 234. Diana Lockwood LSHTM leprosy, leishmaniaiss, skin diseases, clinical trials 1. The INFIR cohort: analysis of histological and immunological features at baseline. Diana NJ Lockwood, Lavanya Suneetha, Karuna Devi Sagili, Meher Vani Chaduvula, Ismail Mohd, Wim van Brakel B, Peter Nicholls, Sujai Suneetha. PLoS Negl Trop Dis 2011 Dec;5(12):e1327. Epub 2011 Dec 13. This study showed that up regulatory cytokines are present in Leprosy Type 1 reactions 2. Early Diagnosis of Neuropathy in Leprosy-Comparing Diagnostic Tests in a Large Prospective Study (the INFIR Cohort Study). Van Brakel WH, Nicholls PG, Wilder-Smith EP, Das L, Barkataki P and Lockwood DN; on behalf of the INFIR Study Group. PLoS Negl Trop Dis 2008 2(4):e212. This finding from a prospective cohort study showed that temperature sensation is the first modality to be affected in leprosy neuropathy 3. A phase two randomised controlled double blind trial of high dose intravenous methylprednisolone and oral prednisolone versus intravenous Normal saline and oral prednisolone in individuals with leprosy Type 1 reactions and /or nerve function impairment. Walker SL, Nicholls PG, Dhakal S, Hawksworth RA, Mahat K, Lockwood DNJ. PLoS Negl Trop Dis. 2011 Apr 12;5(4):e1041. This RCT showed that giving 3 days of IV methylprednisolone at the start of reaction treatment was not effective. It is an important negative finding. 4. Monitoring Toxicity Associated with Parenteral Sodium Stibogluconate in the Day-Case Management of Returned Travellers with New World Cutaneous Leishmaniasis. Wise. E, Armstrong M, Watson J Lockwood DN PLoS Negl Trop Dis June 2012 6(6):e1688. This UK based study showed that Imported Cutaneous leishamnasis can be safey treated in the outpatients and has minimal toxicity. 235. Mark Rowland LSHTM Malaria vector control, community randomised trials 5. Investigation of neuropathic pain (NP) in treated leprosy patient in Ethiopia, a cross-sectional study. Haroun OM, Hietaharju A, Bizuneh E, Tesfaye F, Brandsma W, Haanpää M, Rice AS Lockwood DNJ Pain. 2012 Aug; 153(8):1620-4. This was the first study in Africa using standardised tools to measure neuropathic pain and show that 15% of treated leprosy patients have neuropathic pain. 1. West PA, Protopopoff N, Wright A, Kivaju Z, Tigererwa R, Mosha F, Kisinza W, Rowland M, Kleinschmidt I. (2014). Indoor residual spraying in combination with insecticidetreated nets compared to insecticide-treated nets alone for protection against malaria: a cluster randomised trial in Tanzania. PLoS Med 11(4): e1001630. 2. Ngufor C, N’Guessan R, Fagbohoun J, Odjo A, Malone D, Akogbeto M, Rowland M. (2014) Olyset Duo (a pyriproxyfen and permethrin mixture net): an experimental hut trial against pyrethroid resistant Anopheles gambiae and Culex quinquefasciatus in Southern Benin. PLoS ONE 9(4): e93603. 3. N'Guessan R, Ngufor C, Kudom AA, Boko P, Odjo A, Malone D, Rowland M. (2014). Mosquito nets treated with a mixture of chlorfenapyr and alphacypermethrin control pyrethroid resistant Anopheles gambiae and Culex quinquefasciatus Mosquitoes in West Africa. PLoS One. 9(2): e87710. 4. Guidelines for laboratory and field-testing of long-lasting insecticidal nets. WHO/HTM/NTD/WHOPES/2013.3. WHO, Geneva. 5. Rowland M, Boko P, Odjo A, Asidi A, Akogbeto M, et al. (2013) A new long-lasting indoor residual formulation of the organophosphate insecticide pirimiphos methyl for prolonged control of pyrethroid-resistant mosquitoes: an experimental hut trial in Benin. PLoS ONE 8, e69516. 236. Liam Smeeth LSHTM NCDs, genomics, use of electronic health records, primary care 237. Helen Weiss LSHTM epidemiology, randomised controlled trials, HIV, mental health 1. Bhaskaran K, Douglas I, Forbes H, dos-Santos-Silva I, Leon D, Smeeth L. Body mass index and risk of 22 specific cancers: a population-based cohort study of 5.2 million UK adults. Lancet 2014 pii: S0140-6736(14)608928. 2. H3Africa Consortium. Research capacity. Enabling the genomic revolution in Africa. Science. 2014 Jun 20;344(6190):1346-8. 3. Rapsomaniki E, Tiommis A, George J, Pujades-Rodriguez M, Shah AD, Denaxas S, White IR, Caulfield MJ, Deanfield JE, Smeeth L, Williams B, Hingorani A, Hemingway H. Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1.25 million people. Lancet 2014;383:1899-911. 4. Peck R, Mghamba J, Vanobberghen F, Kavishe B, Rugarabamu V, Smeeth L, Hayes R, Grosskurth H, Kapiga S. Preparedness of Tanzanian health facilities for outpatient primary care of hypertension and diabetes: a cross-sectional survey. Lancet Glob Health 2014;2:e285e292. 5. Etyang AO, Munge K, Bunyasi EW, Matata L, Ndila C, Kapesa S, Owiti M, Khandwalla I, Brent AJ, Tsofa B, Kabibu P, Morpeth S, Bauni E, Otiende M, Ojal J, Ayieko P, Knoll MD, Smeeth L, Williams TN, Griffiths UK, Scott JA. Burden of disease in adults admitted to hospital in rural region of coastal Kenya: an analysis of data from linked clinical and demographic surveillance systems. Lancet Glob Health 2014;2:e216-24. 1. Francis JM, Grosskurth H, Changlucha J, Kapiga SH, Weiss HA. The prevalence of alcohol use among young people in Eastern Africa: Systematic review and metaanalysis. Trop Med Int Health. 2014 Jan 31. doi: 10.1111/tmi.12267 238. Suzanne Filteau LSHTM nutrition and infectious diseases 2. Chatterjee S, Naik S, John S, Dabholkar H, Balaji M, Koschosrke M, Varghese M, Rangaswamy T, Weiss HA, Williams P, Patel V, Thornicroft G. Effectiveness of a community-based intervention for people with schizophrenia and their caregivers in India: The COPSI randomised controlled trial. Lancet. 2014 Apr 19;383(9926):1385-94. doi: 10.1016/S01406736(13)62629-X. Epub 2014 Mar 5. 3. Patel V, Weiss HA, Chowdhary N, Naik S, Pednekar S, Chatterjee S, De Silva M, Bhat B, Araya R, King M, Simon G, Verdeli H, Kirkwood BR. The effectiveness of a lay health worker led intervention for depressive and anxiety disorders in primary care: the Manas cluster randomized controlled trial in Goa, India. Lancet Dec 18;376(9758):2086-95. Epub 2010 Dec 13. 4. Vandepitte J, Bukenya J, Weiss HA, Nakubulwa S, Francis SC, Hughes P, Hayes RJ, Grosskurth H. HIV and Other Sexually Transmitted Infections in a Cohort of Women Involved in High-Risk Sexual Behavior in Kampala, Uganda. Sexually Transmitted Diseases. 38(4):316-323, April 2011. 5. Vandepitte J, Weiss HA, Bukenya J, Nakubulwa S, Mayanja Y, Matovu G, Kyakuwa N, Hughes P, Hayes R, Grosskurth H. Alcohol Use, Mycoplasma genitalium, and Other STIs Associated With HIV Incidence Among Women at High Risk in Kampala, Uganda. 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